Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002008-TA|BGIBMGA002008-PA|IPR002110|Ankyrin
(589 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 227 1e-58
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 227 1e-58
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 227 1e-58
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 227 1e-58
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 227 1e-58
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 227 1e-58
AF312028-1|AAG60045.1| 782|Homo sapiens myosin binding subunit ... 221 6e-57
AB209452-1|BAD92689.1| 736|Homo sapiens protein phosphatase 1, ... 221 6e-57
BC110907-1|AAI10908.1| 515|Homo sapiens PPP1R12B protein protein. 213 1e-54
BC034430-1|AAH34430.1| 386|Homo sapiens PPP1R12B protein protein. 213 1e-54
AL589762-3|CAH73375.1| 982|Homo sapiens protein phosphatase 1, ... 213 1e-54
AL589762-2|CAH73374.1| 386|Homo sapiens protein phosphatase 1, ... 213 1e-54
AL356953-9|CAI15935.1| 982|Homo sapiens protein phosphatase 1, ... 213 1e-54
AL356953-8|CAI15934.1| 386|Homo sapiens protein phosphatase 1, ... 213 1e-54
AF324892-1|AAK00336.1| 982|Homo sapiens myosin phosphatase targ... 213 1e-54
AF324888-1|AAK00337.1| 982|Homo sapiens myosin phosphatase targ... 213 1e-54
AB003062-1|BAA28376.1| 982|Homo sapiens myosin phosphatase targ... 213 1e-54
BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1, ... 142 4e-33
AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1, ... 142 4e-33
AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1, ... 142 4e-33
AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP ... 142 4e-33
AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein. 142 4e-33
BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1, ... 140 1e-32
BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1, ... 140 1e-32
BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1, ... 140 1e-32
BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1, ... 140 1e-32
AL390918-2|CAI15822.1| 940|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL390918-1|CAI15821.1| 1858|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL353143-2|CAH73222.1| 940|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL353143-1|CAH73221.1| 1858|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL161431-1|CAI15548.1| 1858|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL157771-2|CAI16367.1| 940|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL157771-1|CAI16366.1| 1858|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL136132-2|CAH70520.1| 940|Homo sapiens protein ( Human DNA seq... 116 3e-25
AL136132-1|CAH70519.1| 1858|Homo sapiens protein ( Human DNA seq... 116 3e-25
AK127806-1|BAC87143.1| 935|Homo sapiens protein ( Homo sapiens ... 116 3e-25
AB020672-1|BAA74888.2| 1900|Homo sapiens KIAA0865 protein protein. 116 3e-25
AK027086-1|BAB15651.1| 602|Homo sapiens protein ( Homo sapiens ... 110 1e-23
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 102 4e-21
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 102 4e-21
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 102 4e-21
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 102 4e-21
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 102 4e-21
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 102 4e-21
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 102 4e-21
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 101 9e-21
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 101 9e-21
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 101 9e-21
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 101 9e-21
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 98 7e-20
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 98 7e-20
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 98 7e-20
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 98 7e-20
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 98 7e-20
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 98 7e-20
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 98 7e-20
AL121889-2|CAM27345.1| 467|Homo sapiens protein phosphatase 1, ... 93 2e-18
AL031657-2|CAM28212.1| 467|Homo sapiens protein phosphatase 1, ... 93 2e-18
AB177855-1|BAD66833.1| 467|Homo sapiens KIAA0823 splice variant... 93 2e-18
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 92 4e-18
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 92 4e-18
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 92 4e-18
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 92 4e-18
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 92 4e-18
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 92 6e-18
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 92 6e-18
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 92 6e-18
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 92 6e-18
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 90 2e-17
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 89 3e-17
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 89 3e-17
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 89 3e-17
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 88 7e-17
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 86 4e-16
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 86 4e-16
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 86 4e-16
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 84 1e-15
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 84 1e-15
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 84 1e-15
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 84 1e-15
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 81 8e-15
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 81 8e-15
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 81 8e-15
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 81 8e-15
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 81 8e-15
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 77 2e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 77 2e-13
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 77 2e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 77 2e-13
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 77 2e-13
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 77 2e-13
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 77 2e-13
BC112094-1|AAI12095.1| 154|Homo sapiens dysferlin interacting p... 76 3e-13
BC093707-1|AAH93707.1| 154|Homo sapiens dysferlin interacting p... 76 3e-13
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 76 3e-13
AF434846-1|AAO67357.1| 154|Homo sapiens dysferlin-interacting p... 76 3e-13
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 76 4e-13
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 75 5e-13
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 75 5e-13
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 75 5e-13
BC071166-1|AAH71166.1| 142|Homo sapiens PPP1R12B protein protein. 75 7e-13
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 74 1e-12
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 74 2e-12
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 74 2e-12
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 74 2e-12
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 74 2e-12
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 74 2e-12
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 74 2e-12
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 74 2e-12
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AF392450-1|AAL40663.1| 950|Homo sapiens oxysterol-binding prote... 74 2e-12
AF323726-1|AAG53407.2| 927|Homo sapiens OSBP-related protein 1 ... 74 2e-12
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 74 2e-12
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 73 3e-12
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 71 9e-12
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 71 9e-12
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 71 9e-12
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 71 1e-11
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 71 1e-11
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 71 2e-11
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 70 2e-11
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 70 2e-11
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 70 2e-11
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 70 2e-11
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 70 2e-11
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 70 3e-11
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 70 3e-11
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 70 3e-11
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 70 3e-11
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 70 3e-11
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 70 3e-11
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 70 3e-11
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 70 3e-11
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 70 3e-11
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 70 3e-11
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 70 3e-11
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 69 6e-11
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 68 8e-11
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 68 8e-11
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 68 8e-11
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 68 8e-11
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 68 8e-11
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 68 8e-11
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 68 8e-11
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 68 8e-11
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 68 8e-11
DQ224339-1|ABB02425.1| 618|Homo sapiens Ikappa B-zeta variant 3... 68 1e-10
BC060800-1|AAH60800.1| 718|Homo sapiens nuclear factor of kappa... 68 1e-10
AF548362-1|AAN40698.1| 618|Homo sapiens MAIL-S protein. 68 1e-10
AB037925-1|BAB40337.1| 718|Homo sapiens MAIL protein. 68 1e-10
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 67 1e-10
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 67 1e-10
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 67 1e-10
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 67 1e-10
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 67 1e-10
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 67 1e-10
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 67 2e-10
AK091782-1|BAC03746.1| 596|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 67 2e-10
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 66 2e-10
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 66 2e-10
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 66 3e-10
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 66 3e-10
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 66 3e-10
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 66 3e-10
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 66 3e-10
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 66 3e-10
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 66 4e-10
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 66 4e-10
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 66 4e-10
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 66 4e-10
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 66 4e-10
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 66 4e-10
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 66 4e-10
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 66 4e-10
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 66 4e-10
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 66 4e-10
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 66 4e-10
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 66 4e-10
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 66 4e-10
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 66 4e-10
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 66 4e-10
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 66 4e-10
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 66 4e-10
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 66 4e-10
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 66 4e-10
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 66 4e-10
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 66 4e-10
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 66 4e-10
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 66 4e-10
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 66 4e-10
AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens ... 65 6e-10
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 65 8e-10
AL137618-1|CAB70844.1| 479|Homo sapiens hypothetical protein pr... 65 8e-10
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 65 8e-10
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 65 8e-10
BC008030-1|AAH08030.1| 362|Homo sapiens PPP1R12C protein protein. 64 1e-09
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 64 2e-09
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 64 2e-09
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 64 2e-09
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 64 2e-09
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 64 2e-09
AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 64 2e-09
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 64 2e-09
U58334-1|AAC50557.1| 1005|Homo sapiens Bbp/53BP2 protein. 63 2e-09
U09582-1|AAA21597.1| 529|Homo sapiens p53-binding protein protein. 63 2e-09
BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein pr... 63 2e-09
BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS... 63 2e-09
BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS... 63 2e-09
BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS... 63 2e-09
BC058918-1|AAH58918.1| 1127|Homo sapiens tumor protein p53 bindi... 63 2e-09
BC040247-1|AAH40247.1| 1048|Homo sapiens TP53BP2 protein protein. 63 2e-09
AL390918-3|CAI15823.1| 878|Homo sapiens protein ( Human DNA seq... 63 2e-09
AL353143-3|CAH73223.1| 878|Homo sapiens protein ( Human DNA seq... 63 2e-09
AL136132-3|CAH70521.1| 878|Homo sapiens protein ( Human DNA seq... 63 2e-09
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 63 2e-09
AJ318888-1|CAC83012.1| 1128|Homo sapiens ASPP2 protein protein. 63 2e-09
AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat domain-c... 63 2e-09
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 63 3e-09
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 62 4e-09
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 62 5e-09
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 62 5e-09
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 62 5e-09
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 62 5e-09
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 62 5e-09
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 62 5e-09
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 62 5e-09
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 62 5e-09
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 62 5e-09
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 62 5e-09
BC006505-1|AAH06505.1| 282|Homo sapiens acyl-Coenzyme A binding... 62 7e-09
BC001244-1|AAH01244.1| 252|Homo sapiens ASB9 protein protein. 62 7e-09
AL445469-1|CAH71747.1| 282|Homo sapiens acyl-Coenzyme A binding... 62 7e-09
AL358354-1|CAI15093.1| 282|Homo sapiens acyl-Coenzyme A binding... 62 7e-09
AL139141-2|CAI19365.1| 282|Homo sapiens acyl-Coenzyme A binding... 62 7e-09
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 61 9e-09
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 61 9e-09
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 61 9e-09
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 61 9e-09
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 61 9e-09
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 61 9e-09
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 61 9e-09
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 61 9e-09
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 61 9e-09
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 61 9e-09
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 61 9e-09
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 61 9e-09
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 61 9e-09
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 61 9e-09
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 61 9e-09
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 60 2e-08
BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein. 60 2e-08
BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein. 60 2e-08
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 60 2e-08
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 60 2e-08
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 60 2e-08
AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 60 2e-08
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 60 2e-08
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 60 3e-08
M58603-1|AAA36360.1| 968|Homo sapiens nuclear factor kappa-B DN... 60 3e-08
M55643-1|AAA36361.1| 969|Homo sapiens factor KBF1 protein. 60 3e-08
L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase prot... 60 3e-08
BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L (2',5'-o... 60 3e-08
BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein. 60 3e-08
BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein. 60 3e-08
BC051765-1|AAH51765.1| 969|Homo sapiens nuclear factor of kappa... 60 3e-08
BC033210-1|AAH33210.1| 550|Homo sapiens NFKB1 protein protein. 60 3e-08
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 60 3e-08
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 60 3e-08
AY223820-1|AAO30127.1| 968|Homo sapiens nuclear factor of kappa... 60 3e-08
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 60 3e-08
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 60 3e-08
AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L (2',5'-o... 60 3e-08
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 60 3e-08
AF213884-1|AAF35232.1| 968|Homo sapiens nuclear factor of kappa... 60 3e-08
Z82208-2|CAI42769.1| 1385|Homo sapiens BCL6 co-repressor-like 1 ... 59 4e-08
Z82208-1|CAI42768.1| 1711|Homo sapiens BCL6 co-repressor-like 1 ... 59 4e-08
BC044652-1|AAH44652.1| 395|Homo sapiens BCORL1 protein protein. 59 4e-08
AL136450-4|CAI42885.1| 1385|Homo sapiens BCL6 co-repressor-like ... 59 4e-08
AL136450-3|CAI42884.1| 1711|Homo sapiens BCL6 co-repressor-like ... 59 4e-08
AK124676-1|BAC85922.1| 485|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AK074089-1|BAB84915.1| 1696|Homo sapiens FLJ00160 protein protein. 59 4e-08
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 59 4e-08
BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS... 59 5e-08
AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5 ... 59 5e-08
AK129529-1|BAC85179.1| 185|Homo sapiens protein ( Homo sapiens ... 59 5e-08
AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens ... 59 5e-08
AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens ... 59 5e-08
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 59 5e-08
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 58 7e-08
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 58 7e-08
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 58 7e-08
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 58 7e-08
AK095691-1|BAC04608.1| 863|Homo sapiens protein ( Homo sapiens ... 58 7e-08
Z47748-1|CAB94757.1| 969|Homo sapiens NFKB1 protein. 58 9e-08
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 58 9e-08
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 58 9e-08
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 58 9e-08
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 58 9e-08
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 58 9e-08
BC017798-1|AAH17798.1| 239|Homo sapiens ankyrin repeat domain 4... 58 9e-08
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 58 9e-08
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 58 9e-08
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 58 9e-08
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 58 9e-08
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 58 9e-08
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 58 9e-08
AK000196-1|BAA91003.1| 239|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AF025354-1|AAK60412.1| 239|Homo sapiens fetal globin-inducing f... 58 9e-08
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 58 1e-07
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 58 1e-07
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 57 2e-07
BC114220-1|AAI14221.1| 1703|Homo sapiens BCOR protein protein. 57 2e-07
BC009675-1|AAH09675.2| 361|Homo sapiens BCOR protein protein. 57 2e-07
AY316592-1|AAR08265.1| 1755|Homo sapiens BCL-6 corepressor long ... 57 2e-07
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AK000292-1|BAA91061.1| 211|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 57 2e-07
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 57 2e-07
AF317391-1|AAG41429.1| 1721|Homo sapiens BCL-6 corepressor protein. 57 2e-07
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 57 2e-07
AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens ... 57 2e-07
BX537857-1|CAD97864.1| 306|Homo sapiens hypothetical protein pr... 56 3e-07
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 56 3e-07
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 56 4e-07
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 56 4e-07
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 56 4e-07
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 56 4e-07
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 56 4e-07
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 56 4e-07
BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS... 56 5e-07
BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS... 56 5e-07
AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AJ318887-1|CAC83011.2| 1090|Homo sapiens ASPP1 protein protein. 56 5e-07
AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat domain-c... 56 5e-07
AB018314-1|BAA34491.1| 948|Homo sapiens KIAA0771 protein protein. 56 5e-07
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 55 6e-07
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 55 6e-07
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 55 8e-07
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 55 8e-07
DQ314886-1|ABC40745.1| 828|Homo sapiens protein phosphatase 1, ... 54 1e-06
BC104775-1|AAI04776.1| 332|Homo sapiens ANKRD43 protein protein. 54 1e-06
BC104771-1|AAI04772.1| 332|Homo sapiens ANKRD43 protein protein. 54 1e-06
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 54 1e-06
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 54 1e-06
BC069013-1|AAH69013.1| 457|Homo sapiens ANKRD11 protein protein. 54 1e-06
BC064913-1|AAH64913.1| 828|Homo sapiens protein phosphatase 1, ... 54 1e-06
BC032298-1|AAH32298.1| 828|Homo sapiens protein phosphatase 1, ... 54 1e-06
BC020589-1|AAH20589.1| 267|Homo sapiens PPP1R13L protein protein. 54 1e-06
BC001475-1|AAH01475.1| 382|Homo sapiens PPP1R13L protein protein. 54 1e-06
AY869712-1|AAW51146.1| 827|Homo sapiens NFkB interacting protei... 54 1e-06
AY533563-1|AAS45544.1| 2663|Homo sapiens ankyrin repeat-containi... 54 1e-06
AY373756-1|AAR25661.1| 2664|Homo sapiens ankyrin repeat-containi... 54 1e-06
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 54 1e-06
AJ888472-1|CAI60219.1| 828|Homo sapiens inhibitor of apoptosis ... 54 1e-06
AF121775-1|AAF24125.1| 366|Homo sapiens nasopharyngeal carcinom... 54 1e-06
AF078037-1|AAD27005.1| 351|Homo sapiens RelA associated inhibit... 54 1e-06
AF078036-1|AAD27004.1| 351|Homo sapiens RelA associated inhibit... 54 1e-06
AB209186-1|BAD92423.1| 439|Homo sapiens ankyrin repeat domain 1... 54 1e-06
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 54 1e-06
Z97630-4|CAB63057.1| 300|Homo sapiens protein ( Human DNA seque... 54 1e-06
CR456471-1|CAG30357.1| 300|Homo sapiens dJ466N1.4 protein. 54 1e-06
BC104946-1|AAI04947.1| 309|Homo sapiens ankyrin repeat and SOCS... 54 1e-06
BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein. 54 1e-06
BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein. 54 1e-06
BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein. 54 1e-06
BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein. 54 1e-06
BC093883-1|AAH93883.1| 309|Homo sapiens ankyrin repeat and SOCS... 54 1e-06
BC069555-1|AAH69555.1| 309|Homo sapiens ankyrin repeat and SOCS... 54 1e-06
BC069436-1|AAH69436.1| 309|Homo sapiens ankyrin repeat and SOCS... 54 1e-06
BC066909-1|AAH66909.1| 300|Homo sapiens ankyrin repeat domain 5... 54 1e-06
BC014641-1|AAH14641.1| 300|Homo sapiens ankyrin repeat domain 5... 54 1e-06
AL356317-1|CAI39932.1| 309|Homo sapiens ankyrin repeat and SOCS... 54 1e-06
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AF403030-1|AAL57349.1| 308|Homo sapiens ankyrin repeat domain-c... 54 1e-06
U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING dom... 54 2e-06
BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING d... 54 2e-06
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 54 2e-06
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 54 2e-06
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 54 2e-06
AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING d... 54 2e-06
AF038042-1|AAB99978.1| 777|Homo sapiens BRCA1-associated RING d... 54 2e-06
AC016708-1|AAX93130.1| 777|Homo sapiens unknown protein. 54 2e-06
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 53 2e-06
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 53 3e-06
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 53 3e-06
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 53 3e-06
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 53 3e-06
D30758-1|BAA06418.2| 796|Homo sapiens KIAA0050 protein. 53 3e-06
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 53 3e-06
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 53 3e-06
BT009788-1|AAP88790.1| 740|Homo sapiens centaurin, beta 1 protein. 53 3e-06
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 53 3e-06
BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING d... 53 3e-06
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 53 3e-06
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 53 3e-06
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 53 3e-06
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 53 3e-06
BC018543-1|AAH18543.1| 740|Homo sapiens centaurin, beta 1 protein. 53 3e-06
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 53 3e-06
BC012917-1|AAH12917.1| 313|Homo sapiens ankyrin repeat, family ... 53 3e-06
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 53 3e-06
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 53 3e-06
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 53 3e-06
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 53 3e-06
AK096896-1|BAC04888.1| 318|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AK022876-1|BAB14288.1| 313|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 53 3e-06
AF314032-1|AAK01621.1| 313|Homo sapiens ankyrin-repeat family A... 53 3e-06
AF251051-1|AAK34941.1| 313|Homo sapiens ankyrin protein. 53 3e-06
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 53 3e-06
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 53 3e-06
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 53 3e-06
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 53 3e-06
U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma ... 52 4e-06
M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein. 52 4e-06
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 52 4e-06
BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3 p... 52 4e-06
AY337578-1|AAQ17469.1| 233|Homo sapiens ankyrin repeat and SOCS... 52 4e-06
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 52 4e-06
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 52 4e-06
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 52 4e-06
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 52 4e-06
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 52 4e-06
AB024494-1|BAC22089.1| 633|Homo sapiens huntingtin interacting ... 52 4e-06
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 52 6e-06
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 52 6e-06
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 52 6e-06
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AK027869-1|BAB55419.1| 773|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 52 6e-06
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 52 6e-06
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 52 8e-06
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 52 8e-06
BC060843-1|AAH60843.1| 228|Homo sapiens ANKRD46 protein protein. 52 8e-06
BC050396-1|AAH50396.1| 232|Homo sapiens ANKRD46 protein protein. 52 8e-06
BC020817-1|AAH20817.2| 303|Homo sapiens ANKRD2 protein protein. 52 8e-06
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 52 8e-06
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 52 8e-06
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 52 8e-06
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 52 8e-06
AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 52 8e-06
AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 52 8e-06
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 52 8e-06
AL359388-5|CAI14193.1| 300|Homo sapiens ankyrin repeat domain 2... 52 8e-06
AL355315-10|CAI15462.1| 300|Homo sapiens ankyrin repeat domain ... 52 8e-06
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 52 8e-06
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 52 8e-06
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 52 8e-06
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 52 8e-06
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 52 8e-06
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 52 8e-06
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 52 8e-06
AB077205-1|BAD23947.1| 228|Homo sapiens ankyrin repeat small pr... 52 8e-06
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 52 8e-06
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 52 8e-06
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 52 8e-06
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 52 8e-06
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 51 1e-05
CR769776-11|CAI95383.1| 823|Homo sapiens ankyrin repeat domain ... 51 1e-05
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 51 1e-05
BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 2... 51 1e-05
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 51 1e-05
AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 2... 51 1e-05
AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 2... 51 1e-05
AK125596-1|BAC86214.1| 235|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 51 1e-05
BC127726-1|AAI27727.1| 165|Homo sapiens MGC26718 protein protein. 50 2e-05
BC022023-1|AAH22023.1| 117|Homo sapiens similar to ankyrin repe... 50 2e-05
AL807776-2|CAH69986.2| 584|Homo sapiens ankyrin repeat and ster... 50 2e-05
AL353782-3|CAH71296.2| 584|Homo sapiens ankyrin repeat and ster... 50 2e-05
U16258-1|AAA85819.1| 481|Homo sapiens I kappa BR protein. 50 2e-05
BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa... 50 2e-05
AJ249601-1|CAB63467.1| 559|Homo sapiens IkappaBR protein. 50 2e-05
AB209126-1|BAD92363.1| 897|Homo sapiens I-kappa-B-related prote... 50 2e-05
BC126188-1|AAI26189.1| 475|Homo sapiens ankyrin repeat, SAM and... 50 3e-05
BC126186-1|AAI26187.1| 475|Homo sapiens ankyrin repeat, SAM and... 50 3e-05
BC034963-1|AAH34963.1| 393|Homo sapiens ASZ1 protein protein. 50 3e-05
AK093445-1|BAC04167.1| 475|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AK092782-1|BAC03975.1| 206|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AF461259-1|AAL68815.1| 475|Homo sapiens GASZ protein. 50 3e-05
BX649567-2|CAH71137.1| 823|Homo sapiens ankyrin repeat domain 2... 49 4e-05
AK098736-1|BAC05399.1| 181|Homo sapiens protein ( Homo sapiens ... 49 4e-05
AK092706-1|BAC03953.1| 575|Homo sapiens protein ( Homo sapiens ... 49 4e-05
>D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target
subunit 1 protein.
Length = 1030
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/194 (30%), Positives = 88/194 (45%), Gaps = 32/194 (16%)
Query: 281 DEAPSWRRSASFRNRQQDSATRIKASSCPSIPPLPQSTLAAIELQKKALEPNN------- 333
+E ++ +S SF RQ D + +SS PS P T AA LQK L +
Sbjct: 544 NEGSTYHKSCSFGRRQDD----LISSSVPSTTSTPTVTSAA-GLQKSLLSSTSTTTKITT 598
Query: 334 -SENANTNEDVQTRISPAERRDKEN----------------NARIALXXXXXXXXXXXXX 376
S +A T R+ + +KE NA +
Sbjct: 599 GSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSS 658
Query: 377 QAPVR---RSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNG 433
VR RS++ PVRDEESE+QRKA +++ R++RRSTQGVTL +++ AE+ + + S
Sbjct: 659 TTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTR 718
Query: 434 TTESSTPTNVKKDE 447
T E K+++
Sbjct: 719 TREQENEEKEKEEK 732
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein.
Length = 1030
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/194 (30%), Positives = 88/194 (45%), Gaps = 32/194 (16%)
Query: 281 DEAPSWRRSASFRNRQQDSATRIKASSCPSIPPLPQSTLAAIELQKKALEPNN------- 333
+E ++ +S SF RQ D + +SS PS P T AA LQK L +
Sbjct: 544 NEGSTYHKSCSFGRRQDD----LISSSVPSTTSTPTVTSAA-GLQKSLLSSTSTTTKITT 598
Query: 334 -SENANTNEDVQTRISPAERRDKEN----------------NARIALXXXXXXXXXXXXX 376
S +A T R+ + +KE NA +
Sbjct: 599 GSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSS 658
Query: 377 QAPVR---RSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNG 433
VR RS++ PVRDEESE+QRKA +++ R++RRSTQGVTL +++ AE+ + + S
Sbjct: 659 TTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTR 718
Query: 434 TTESSTPTNVKKDE 447
T E K+++
Sbjct: 719 TREQENEEKEKEEK 732
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein.
Length = 730
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 73.3 bits (172), Expect = 2e-12
Identities = 60/192 (31%), Positives = 86/192 (44%), Gaps = 32/192 (16%)
Query: 281 DEAPSWRRSASFRNRQQDSATRIKASSCPSIPPLPQSTLAAIELQKKALEPNN------- 333
+E ++ +S SF RQ D + +SS PS P T AA LQK L +
Sbjct: 544 NEGSTYHKSCSFGRRQDD----LISSSVPSTTSTPTVTSAA-GLQKSLLSSTSTTTKITT 598
Query: 334 -SENANTNEDVQTRISPAERRDKEN----------------NARIALXXXXXXXXXXXXX 376
S +A T R+ + +KE NA +
Sbjct: 599 GSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTVGTVSS 658
Query: 377 QAPVR---RSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNG 433
VR RS++ PVRDEESE+QRKA +++ R++RRSTQGVTL +++ AE+ + + S
Sbjct: 659 TTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTR 718
Query: 434 TTESSTPTNVKK 445
T E KK
Sbjct: 719 TREQENEEKKKK 730
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein.
Length = 692
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 68.1 bits (159), Expect = 8e-11
Identities = 31/64 (48%), Positives = 45/64 (70%)
Query: 382 RSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNGTTESSTPT 441
RS++ PVRDEESE+QRKA +++ R++RRSTQGVTL +++ AE+ + + S T E
Sbjct: 608 RSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQKKKK 667
Query: 442 NVKK 445
KK
Sbjct: 668 KKKK 671
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase target
subunit 1 variant 2 protein.
Length = 974
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 67.3 bits (157), Expect = 1e-10
Identities = 30/67 (44%), Positives = 47/67 (70%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNGTTESSTP 440
RRS++ PVRDEESE+QRKA +++ ++RRSTQGVTL +++ AE+ + + S T E
Sbjct: 610 RRSYLTPVRDEESESQRKARSRQAGQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENE 669
Query: 441 TNVKKDE 447
K+++
Sbjct: 670 EKEKEEK 676
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase target
subunit 1 variant protein.
Length = 995
Score = 227 bits (554), Expect = 1e-58
Identities = 109/222 (49%), Positives = 149/222 (67%), Gaps = 2/222 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACIDDN+DMV+FLV +GA++N+ DNEGW PLHA ASCG++ IA +L+ GA V AVN +G
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEG 139
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+ P+DIAE +AM +LLQ ++ +GVD E +R E ++ DAR+W G++ +VR K+G
Sbjct: 140 DTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSG 199
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
GT LHVAAAKGY +V K L++ D + DY+GWTPLHAAA WG++EA +L+ D
Sbjct: 200 GTALHVAAAKGYTEVLKLLIQ-AGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
+ N GQT D+ D I +LEE K + + K SP
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSP 300
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/194 (30%), Positives = 88/194 (45%), Gaps = 32/194 (16%)
Query: 281 DEAPSWRRSASFRNRQQDSATRIKASSCPSIPPLPQSTLAAIELQKKALEPNN------- 333
+E ++ +S SF RQ D + +SS PS P T AA LQK L +
Sbjct: 544 NEGSTYHKSCSFGRRQDD----LISSSVPSTTSTPTVTSAA-GLQKSLLSSTSTTTKITT 598
Query: 334 -SENANTNEDVQTRISPAERRDKEN----------------NARIALXXXXXXXXXXXXX 376
S +A T R+ + +KE NA +
Sbjct: 599 GSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSS 658
Query: 377 QAPVR---RSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLVKKKSSNG 433
VR RS++ PVRDEESE+QRKA +++ R++RRSTQGVTL +++ AE+ + + S
Sbjct: 659 TTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTR 718
Query: 434 TTESSTPTNVKKDE 447
T E K+++
Sbjct: 719 TREQENEEKEKEEK 732
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+GA++ +
Sbjct: 45 LAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDN 104
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G +P+ A S D+ + +I + G + N+E DT + A E A+ ++ ++
Sbjct: 105 EGWIPLHAAASCGYLDIAEFLIGQ-GAHV-GAVNSEGDTPLDIAEEEAMEELLQ-NEVNR 161
Query: 121 GGTPLHVAAAKG---YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G + A + + A+ L + + G T LH AA G E LL++
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQA 221
Query: 178 GADPHLKNYSGQTCL 192
G D ++K+Y G T L
Sbjct: 222 GYDVNIKDYDGWTPL 236
>AF312028-1|AAG60045.1| 782|Homo sapiens myosin binding subunit 85
protein.
Length = 782
Score = 221 bits (540), Expect = 6e-57
Identities = 110/208 (52%), Positives = 141/208 (67%), Gaps = 2/208 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NL++V FLV GA VN+ DNEGWTPLH ASCG++ IARYLL GA++AAVN DG
Sbjct: 108 ACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDG 167
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+LP+D+AESDAM LL+ I +GVD E ++ AE + L+ D R W G + E R +TG
Sbjct: 168 DLPLDLAESDAMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTG 227
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
+ LHVAAAKGYI+V + LL+ DP+ D +GWTPLHAAA WG ++A LL + G
Sbjct: 228 ASALHVAAAKGYIEVMRLLLQ-AGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALK 209
++GQ DL D + S LEE A K
Sbjct: 287 DSLTHAGQRPCDLADEEVLSLLEELARK 314
Score = 64.9 bits (151), Expect = 8e-10
Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLV-KKKSSNGTTESST 439
RRS+ PVRDEESE+QRKA ++ +R++RRSTQGVTL ++K AE+ K S +S
Sbjct: 530 RRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLD 589
Query: 440 PTNVKKDETPTPATTDNGSFELEDAGRASPRSGAA 474
P+ ++ P +D+ + E P AA
Sbjct: 590 PS--RRPRVPGVENSDSPAQRAEAPDGQGPGPQAA 622
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G + LH + + R+L+E GA V + +G P+ +A S D+ + ++ G
Sbjct: 100 DGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSH-GA 158
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLED--C- 144
+ + N++ D + A A+ G ++ + G + V AAK + + LL D C
Sbjct: 159 NI-AAVNSDGDLPLDLAESDAMEGLLKAEIARRG---VDVEAAKRAEE--ELLLHDTRCW 212
Query: 145 ---NADPDC-VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
A P+ G + LH AA G E LLL+ G DP L++ G T L
Sbjct: 213 LNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPL 264
>AB209452-1|BAD92689.1| 736|Homo sapiens protein phosphatase 1,
regulatory subunit 12C variant protein.
Length = 736
Score = 221 bits (540), Expect = 6e-57
Identities = 110/208 (52%), Positives = 141/208 (67%), Gaps = 2/208 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NL++V FLV GA VN+ DNEGWTPLH ASCG++ IARYLL GA++AAVN DG
Sbjct: 64 ACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDG 123
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTG 121
+LP+D+AESDAM LL+ I +GVD E ++ AE + L+ D R W G + E R +TG
Sbjct: 124 DLPLDLAESDAMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTG 183
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
+ LHVAAAKGYI+V + LL+ DP+ D +GWTPLHAAA WG ++A LL + G
Sbjct: 184 ASALHVAAAKGYIEVMRLLLQ-AGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 242
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALK 209
++GQ DL D + S LEE A K
Sbjct: 243 DSLTHAGQRPCDLADEEVLSLLEELARK 270
Score = 64.5 bits (150), Expect = 1e-09
Identities = 40/107 (37%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLV-KKKSSNGTTESST 439
RRS+ PVRDEESE+QRKA ++ +R++RRSTQGVTL ++K AE+ K S +S
Sbjct: 485 RRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLD 544
Query: 440 PTNVKKDETPTPATTDN-GSFELEDAGRASPRSGAAEATVTLPLRRP 485
P+ ++ P +D+ E D P++ V R P
Sbjct: 545 PS--RRPRVPGVENSDSPAQREAPDGQGPGPQAAREHRKVGKEWRGP 589
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G + LH + + R+L+E GA V + +G P+ +A S D+ + ++ G
Sbjct: 56 DGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSH-GA 114
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLED--C- 144
+ + N++ D + A A+ G ++ + G + V AAK + + LL D C
Sbjct: 115 NI-AAVNSDGDLPLDLAESDAMEGLLKAEIARRG---VDVEAAKRAEE--ELLLHDTRCW 168
Query: 145 ---NADPDC-VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
A P+ G + LH AA G E LLL+ G DP L++ G T L
Sbjct: 169 LNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPL 220
>BC110907-1|AAI10908.1| 515|Homo sapiens PPP1R12B protein protein.
Length = 515
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>BC034430-1|AAH34430.1| 386|Homo sapiens PPP1R12B protein protein.
Length = 386
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AL589762-3|CAH73375.1| 982|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 12B protein.
Length = 982
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 60.9 bits (141), Expect = 1e-08
Identities = 26/44 (59%), Positives = 38/44 (86%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQ 424
RRS++ PVRDEE+E+ RKA +++ R+TRRSTQGVTL +++ AE+
Sbjct: 616 RRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAER 659
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AL589762-2|CAH73374.1| 386|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 12B protein.
Length = 386
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AL356953-9|CAI15935.1| 982|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 12B protein.
Length = 982
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 60.9 bits (141), Expect = 1e-08
Identities = 26/44 (59%), Positives = 38/44 (86%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQ 424
RRS++ PVRDEE+E+ RKA +++ R+TRRSTQGVTL +++ AE+
Sbjct: 616 RRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAER 659
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AL356953-8|CAI15934.1| 386|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 12B protein.
Length = 386
Score = 213 bits (521), Expect = 1e-54
Identities = 102/203 (50%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++GVD E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 50.8 bits (116), Expect = 1e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGVDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AF324892-1|AAK00336.1| 982|Homo sapiens myosin phosphatase target
subunit 2 protein.
Length = 982
Score = 213 bits (520), Expect = 1e-54
Identities = 101/203 (49%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++G+D E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 60.9 bits (141), Expect = 1e-08
Identities = 26/44 (59%), Positives = 38/44 (86%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQ 424
RRS++ PVRDEE+E+ RKA +++ R+TRRSTQGVTL +++ AE+
Sbjct: 616 RRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAER 659
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AF324888-1|AAK00337.1| 982|Homo sapiens myosin phosphatase target
subunit 2 protein.
Length = 982
Score = 213 bits (520), Expect = 1e-54
Identities = 101/203 (49%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++G+D E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 60.9 bits (141), Expect = 1e-08
Identities = 26/44 (59%), Positives = 38/44 (86%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQ 424
RRS++ PVRDEE+E+ RKA +++ R+TRRSTQGVTL +++ AE+
Sbjct: 616 RRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAER 659
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>AB003062-1|BAA28376.1| 982|Homo sapiens myosin phosphatase
targeting/regulatory subunit protein.
Length = 982
Score = 213 bits (520), Expect = 1e-54
Identities = 101/203 (49%), Positives = 139/203 (68%), Gaps = 2/203 (0%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA Y + GA V VN +G
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEG 157
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTG 121
E+P D+AE AM DLL + + ++G+D E+SR E ++ DAR+W G +E VR ++G
Sbjct: 158 EVPSDLAEEPAMKDLLLEQVKKQGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSG 217
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LHVAAAKGY +V + L++ + + DY+GWTPLHAAA WG KEA ++L + D
Sbjct: 218 ATALHVAAAKGYSEVLRLLIQ-AGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 182 HLKNYSGQTCLDLVDPSISSWLE 204
++N GQT D+ D + LE
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLE 299
Score = 60.9 bits (141), Expect = 1e-08
Identities = 26/44 (59%), Positives = 38/44 (86%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQ 424
RRS++ PVRDEE+E+ RKA +++ R+TRRSTQGVTL +++ AE+
Sbjct: 616 RRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAER 659
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/195 (24%), Positives = 84/195 (43%), Gaps = 6/195 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+G P+ A S ++ + I+ + EV SD E + + +K
Sbjct: 123 EGWTPLHAAASCGYLNIAEYFINHGASVGIVNSEGEVP---SDLAEEPAMKDLLLEQVKK 179
Query: 121 GGTPLHVA---AAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
G L + + + A+ L + G T LH AA G E LL++
Sbjct: 180 QGIDLEQSRKEEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQA 239
Query: 178 GADPHLKNYSGQTCL 192
G + ++++Y G T L
Sbjct: 240 GYELNVQDYDGWTPL 254
>BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 142 bits (343), Expect = 4e-33
Identities = 76/197 (38%), Positives = 116/197 (58%), Gaps = 6/197 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 109 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 168
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGY-VEVRDLK 119
+P D+ E + D+++ + +G+ EK R A +++D G ++ D +
Sbjct: 169 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQ 228
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G T LH+A A GY+ A+ LL D D D++GW PLHAAA WGQ + A LL+ GA
Sbjct: 229 -GATLLHIAGANGYLRAAELLL-DHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGA 286
Query: 180 DPHLKNYSGQTCLDLVD 196
+ + +DL +
Sbjct: 287 SLSARTSMDEMPIDLCE 303
Score = 52.0 bits (119), Expect = 6e-06
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
L E L+ HG V+ D +GW PLHA A G + +A L+ GA ++A E+P+D+
Sbjct: 242 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDL 301
Query: 69 AESDAMADLL 78
E + LL
Sbjct: 302 CEEEEFKVLL 311
>AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 142 bits (343), Expect = 4e-33
Identities = 76/197 (38%), Positives = 116/197 (58%), Gaps = 6/197 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 109 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 168
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGY-VEVRDLK 119
+P D+ E + D+++ + +G+ EK R A +++D G ++ D +
Sbjct: 169 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQ 228
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G T LH+A A GY+ A+ LL D D D++GW PLHAAA WGQ + A LL+ GA
Sbjct: 229 -GATLLHIAGANGYLRAAELLL-DHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGA 286
Query: 180 DPHLKNYSGQTCLDLVD 196
+ + +DL +
Sbjct: 287 SLSARTSMDEMPIDLCE 303
Score = 52.0 bits (119), Expect = 6e-06
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
L E L+ HG V+ D +GW PLHA A G + +A L+ GA ++A E+P+D+
Sbjct: 242 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDL 301
Query: 69 AESDAMADLL 78
E + LL
Sbjct: 302 CEEEEFKVLL 311
>AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 142 bits (343), Expect = 4e-33
Identities = 76/197 (38%), Positives = 116/197 (58%), Gaps = 6/197 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 109 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 168
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGY-VEVRDLK 119
+P D+ E + D+++ + +G+ EK R A +++D G ++ D +
Sbjct: 169 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQ 228
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G T LH+A A GY+ A+ LL D D D++GW PLHAAA WGQ + A LL+ GA
Sbjct: 229 -GATLLHIAGANGYLRAAELLL-DHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGA 286
Query: 180 DPHLKNYSGQTCLDLVD 196
+ + +DL +
Sbjct: 287 SLSARTSMDEMPIDLCE 303
Score = 52.0 bits (119), Expect = 6e-06
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
L E L+ HG V+ D +GW PLHA A G + +A L+ GA ++A E+P+D+
Sbjct: 242 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDL 301
Query: 69 AESDAMADLL 78
E + LL
Sbjct: 302 CEEEEFKVLL 311
>AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP
protein.
Length = 567
Score = 142 bits (343), Expect = 4e-33
Identities = 76/197 (38%), Positives = 116/197 (58%), Gaps = 6/197 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 109 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 168
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGY-VEVRDLK 119
+P D+ E + D+++ + +G+ EK R A +++D G ++ D +
Sbjct: 169 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQ 228
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G T LH+A A GY+ A+ LL D D D++GW PLHAAA WGQ + A LL+ GA
Sbjct: 229 -GATLLHIAGANGYLRAAELLL-DHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGA 286
Query: 180 DPHLKNYSGQTCLDLVD 196
+ + +DL +
Sbjct: 287 SLSARTSMDEMPIDLCE 303
Score = 52.0 bits (119), Expect = 6e-06
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
L E L+ HG V+ D +GW PLHA A G + +A L+ GA ++A E+P+D+
Sbjct: 242 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDL 301
Query: 69 AESDAMADLL 78
E + LL
Sbjct: 302 CEEEEFKVLL 311
>AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein.
Length = 578
Score = 142 bits (343), Expect = 4e-33
Identities = 76/197 (38%), Positives = 116/197 (58%), Gaps = 6/197 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 120 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 179
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGY-VEVRDLK 119
+P D+ E + D+++ + +G+ EK R A +++D G ++ D +
Sbjct: 180 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQ 239
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G T LH+A A GY+ A+ LL D D D++GW PLHAAA WGQ + A LL+ GA
Sbjct: 240 -GATLLHIAGANGYLRAAELLL-DHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGA 297
Query: 180 DPHLKNYSGQTCLDLVD 196
+ + +DL +
Sbjct: 298 SLSARTSMDEMPIDLCE 314
Score = 52.0 bits (119), Expect = 6e-06
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
L E L+ HG V+ D +GW PLHA A G + +A L+ GA ++A E+P+D+
Sbjct: 253 LRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDL 312
Query: 69 AESDAMADLL 78
E + LL
Sbjct: 313 CEEEEFKVLL 322
>BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 140 bits (340), Expect = 1e-32
Identities = 84/224 (37%), Positives = 120/224 (53%), Gaps = 7/224 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CIDD +MV+ L+ GA++N D+E WTPLHA A+CG + + L+ SGA++ AVN DG
Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGN 171
Query: 64 LPVDIAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+P D+ + + D L+ + ++G+ E +R ++ D R G L
Sbjct: 172 MPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDH 231
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LHVAAA G+ + A LLE A D +GW PLHAAA WGQ LL+ GAD
Sbjct: 232 GATLLHVAAANGFSEAAALLLEH-RASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGAD 290
Query: 181 PHLKNYSGQTCLDLV-DPSISSWLEEAALK--APRRVNNNKRKL 221
+ K+ +T LD+ D + + L E K A R + +R L
Sbjct: 291 LNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSL 334
>BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 140 bits (340), Expect = 1e-32
Identities = 84/224 (37%), Positives = 120/224 (53%), Gaps = 7/224 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CIDD +MV+ L+ GA++N D+E WTPLHA A+CG + + L+ SGA++ AVN DG
Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGN 171
Query: 64 LPVDIAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+P D+ + + D L+ + ++G+ E +R ++ D R G L
Sbjct: 172 MPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDH 231
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LHVAAA G+ + A LLE A D +GW PLHAAA WGQ LL+ GAD
Sbjct: 232 GATLLHVAAANGFSEAAALLLEH-RASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGAD 290
Query: 181 PHLKNYSGQTCLDLV-DPSISSWLEEAALK--APRRVNNNKRKL 221
+ K+ +T LD+ D + + L E K A R + +R L
Sbjct: 291 LNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSL 334
>BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 140 bits (340), Expect = 1e-32
Identities = 84/224 (37%), Positives = 120/224 (53%), Gaps = 7/224 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CIDD +MV+ L+ GA++N D+E WTPLHA A+CG + + L+ SGA++ AVN DG
Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGN 171
Query: 64 LPVDIAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+P D+ + + D L+ + ++G+ E +R ++ D R G L
Sbjct: 172 MPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDH 231
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LHVAAA G+ + A LLE A D +GW PLHAAA WGQ LL+ GAD
Sbjct: 232 GATLLHVAAANGFSEAAALLLEH-RASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGAD 290
Query: 181 PHLKNYSGQTCLDLV-DPSISSWLEEAALK--APRRVNNNKRKL 221
+ K+ +T LD+ D + + L E K A R + +R L
Sbjct: 291 LNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSL 334
>BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 140 bits (340), Expect = 1e-32
Identities = 84/224 (37%), Positives = 120/224 (53%), Gaps = 7/224 (3%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CIDD +MV+ L+ GA++N D+E WTPLHA A+CG + + L+ SGA++ AVN DG
Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGN 171
Query: 64 LPVDIAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+P D+ + + D L+ + ++G+ E +R ++ D R G L
Sbjct: 172 MPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDH 231
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LHVAAA G+ + A LLE A D +GW PLHAAA WGQ LL+ GAD
Sbjct: 232 GATLLHVAAANGFSEAAALLLEH-RASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGAD 290
Query: 181 PHLKNYSGQTCLDLV-DPSISSWLEEAALK--APRRVNNNKRKL 221
+ K+ +T LD+ D + + L E K A R + +R L
Sbjct: 291 LNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSL 334
>AL390918-2|CAI15822.1| 940|Homo sapiens protein ( Human DNA
sequence from clone RP11-569E4 on chromosome 13. ).
Length = 940
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL390918-1|CAI15821.1| 1858|Homo sapiens protein ( Human DNA
sequence from clone RP11-569E4 on chromosome 13. ).
Length = 1858
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL353143-2|CAH73222.1| 940|Homo sapiens protein ( Human DNA
sequence from clone RP11-383F12 on chromosome 13. ).
Length = 940
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL353143-1|CAH73221.1| 1858|Homo sapiens protein ( Human DNA
sequence from clone RP11-383F12 on chromosome 13. ).
Length = 1858
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL161431-1|CAI15548.1| 1858|Homo sapiens protein ( Human DNA
sequence from clone RP11-54H7 on chromosome 13. ).
Length = 1858
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL157771-2|CAI16367.1| 940|Homo sapiens protein ( Human DNA
sequence from clone RP11-67J18 on chromosome 13. ).
Length = 940
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL157771-1|CAI16366.1| 1858|Homo sapiens protein ( Human DNA
sequence from clone RP11-67J18 on chromosome 13. ).
Length = 1858
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL136132-2|CAH70520.1| 940|Homo sapiens protein ( Human DNA
sequence from clone RP11-141M24 on chromosome
13q33.1-34. ).
Length = 940
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AL136132-1|CAH70519.1| 1858|Homo sapiens protein ( Human DNA
sequence from clone RP11-141M24 on chromosome
13q33.1-34. ).
Length = 1858
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 104 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 163
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 164 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 223
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 224 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 282
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 283 LVNCNEEKASDI---AASEFIEEMLLKA 307
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 229 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 288
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 289 EKASDIAASEFIEEMLLK 306
>AK127806-1|BAC87143.1| 935|Homo sapiens protein ( Homo sapiens
cDNA FLJ45907 fis, clone OCBBF3027969, weakly similar
to Homo sapiens myosin IIIA (MYO3A). ).
Length = 935
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 126 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 185
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 186 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 245
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 246 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 304
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 305 LVNCNEEKASDI---AASEFIEEMLLKA 329
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 251 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 310
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 311 EKASDIAASEFIEEMLLK 328
>AB020672-1|BAA74888.2| 1900|Homo sapiens KIAA0865 protein protein.
Length = 1900
Score = 116 bits (278), Expect = 3e-25
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 8/208 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + E L+ G +VN D + WTP+H +C I L+ +GA+V + +G +P+
Sbjct: 146 DNAFIAEILIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPL 205
Query: 67 DIA-ESDAMADLLQKVIDEKGVDCEKSRNAEVD---TLMSDAREWALHGYVEVRDLKTGG 122
D A E + +L +DE GVD R ++ ++++D + + G G
Sbjct: 206 DYAVEGTESSSILLTYLDENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGV 265
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PH
Sbjct: 266 TLLHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPH 324
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKA 210
L N + + D+ + S ++EE LKA
Sbjct: 325 LVNCNEEKASDI---AASEFIEEMLLKA 349
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 271 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 330
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 331 EKASDIAASEFIEEMLLK 348
>AK027086-1|BAB15651.1| 602|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23433 fis, clone HRC12009. ).
Length = 602
Score = 110 bits (265), Expect = 1e-23
Identities = 61/137 (44%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Query: 74 MADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV-EVRDLKTGGTPLHVAAAKG 132
M LL+ I +GVD E ++ AE + L+ D R W G + E R +TG + LHVAAAKG
Sbjct: 1 MEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKG 60
Query: 133 YIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
YI+V + LL+ DP+ D +GWTPLHAAA WG ++A LL + G ++GQ
Sbjct: 61 YIEVMRLLLQ-AGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPC 119
Query: 193 DLVDPSISSWLEEAALK 209
DL D + S LEE A K
Sbjct: 120 DLADEEVLSLLEELARK 136
Score = 64.5 bits (150), Expect = 1e-09
Identities = 40/107 (37%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLV-KKKSSNGTTESST 439
RRS+ PVRDEESE+QRKA ++ +R++RRSTQGVTL ++K AE+ K S +S
Sbjct: 351 RRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLD 410
Query: 440 PTNVKKDETPTPATTDN-GSFELEDAGRASPRSGAAEATVTLPLRRP 485
P+ ++ P +D+ E D P++ V R P
Sbjct: 411 PS--RRPRVPGVENSDSPAQREAPDGQGPGPQAAREHRKVGKEWRGP 455
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
++++ L+ G D D +GWTPLHA A G R L E G + ++ + G+ P D+
Sbjct: 62 IEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDL 121
Query: 69 AESDAMADLLQKV 81
A+ + ++ LL+++
Sbjct: 122 ADEEVLS-LLEEL 133
Score = 32.3 bits (70), Expect = 4.9
Identities = 18/63 (28%), Positives = 30/63 (47%)
Query: 24 RGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVID 83
R G + LH A+ G+I + R LL++G D + DG P+ A + D + + +
Sbjct: 44 RHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAE 103
Query: 84 EKG 86
G
Sbjct: 104 HGG 106
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase 2
protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 664 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 723
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 724 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 783
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 784 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 842
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 843 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 897
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 197 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 256
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 257 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 316
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 317 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 375
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 376 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 416
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 513 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 572
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 573 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 631
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 632 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 682
Score = 74.9 bits (176), Expect = 7e-13
Identities = 67/234 (28%), Positives = 106/234 (45%), Gaps = 31/234 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 350 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 409
Query: 62 GELPVDIAESDAMAD---------LLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALH- 110
+ +D+A + + + L+ E V +K + E+ S E ALH
Sbjct: 410 NKSAIDLAPTPQLKERLAYEFQRPLVAAXAREADVTRIKKHLSLEMVIQASQTHETALHC 469
Query: 111 ----GYVEVRD-----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCV 151
Y + + L+ G TPLHVA+ K + DV + +++ A + +
Sbjct: 470 AAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKH-EAKVNAL 528
Query: 152 DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEE 205
D G T LH AA G + LLL +G DP++ + G T L + + ++ L+E
Sbjct: 529 DNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQE 582
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 636 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 695
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 696 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 749
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 750 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 807
Query: 185 NYSG 188
+ G
Sbjct: 808 DKGG 811
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 172 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 230
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 231 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 272
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 544 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 597
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 598 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 656
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 657 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 715
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 716 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 766
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 172 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 231
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 232 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 285
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 286 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 341
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 160 TPLHFAAXFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 218
Query: 183 LKN 185
++
Sbjct: 219 ARD 221
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 131 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDD 189
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 190 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 225
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 226 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 264
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 102 bits (244), Expect = 4e-21
Identities = 83/235 (35%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 565 NACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD 624
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCEKSRNAEVDTL- 100
G P+D + + D + DLL +K+ V+C ++ L
Sbjct: 625 GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLH 684
Query: 101 ------MSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
+ E+ L +V GG PLH AA+ G++DVA L++ NA + D
Sbjct: 685 LAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIK-YNACVNATDK 743
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+TPLH AA G+ + ALLL GADP LKN GQT LDLV S L AA+
Sbjct: 744 WAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM 798
Score = 85.0 bits (201), Expect = 7e-16
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ HGAD N DN +TPLH A G I + LL+ GA+ N D
Sbjct: 97 NACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTD 156
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 157 GRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLH 216
Query: 111 ---GYVEVRD----LKTGG----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY V+ L+ G PLH A + G+ +V + L++ A + +D
Sbjct: 217 LAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKH-GACVNAMDL 275
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL +GADP L N ++ +DL
Sbjct: 276 WQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDL 316
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE +V H A VN DN G T LH A CG + R LL G D ++ G + +
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG 473
Query: 70 ESDAMADLLQKVIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLK-TGGTPLHV 127
++ + LLQ+ I + ++ A + ++ V RD++ TPLH
Sbjct: 474 -NENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHF 532
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
AA + V + LL+ AD D G PLH A +G E A LL+K GA
Sbjct: 533 AAGYNRVSVVEYLLQH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGA 583
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L++ GA V + P+
Sbjct: 537 NRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPL 596
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + ++ G +++DL G L
Sbjct: 597 HEAAAKGKYEIC-KLLLQHGADPTK-KNRDGNTPLDLVKD----GDTDIQDLLRGDAALL 650
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + K L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 651 DAAKKGCLARVKKLSSPDNV--NCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQ 708
Query: 185 NYSG 188
+ G
Sbjct: 709 DKGG 712
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/102 (39%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 103 DAREWALHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
D E+ L V+ GG PLH A + G+ +V LL ADP+ D +TPLH
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNARDNWNYTPLHE 130
Query: 162 AALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL 203
AA+ G+ + +LL+ GA+P ++N G+T LDL DPS + L
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVL 172
Score = 61.3 bits (142), Expect = 9e-09
Identities = 69/231 (29%), Positives = 108/231 (46%), Gaps = 22/231 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L L+++G D N +G+T L G ++ + LL+ G + D +L ++
Sbjct: 445 HLQTCRLLLSYGCDPNIISLQGFTALQM----GNENVQQ-LLQEGISLGNSEADRQL-LE 498
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDLKT 120
A++ + + ++K+ + V+C + L A E+ L +V
Sbjct: 499 AAKAGDV-ETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK 557
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
GG PLH A + G+ +VA+ L++ A + D +TPLH AA G+ E LLL+ GA
Sbjct: 558 GGLVPLHNACSYGHYEVAELLVKH-GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGA 616
Query: 180 DPHLKNYSGQTCLDLV---DPSISSWLE-EAAL--KAPRRVNNNKRKLSPP 224
DP KN G T LDLV D I L +AAL A + +KLS P
Sbjct: 617 DPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 11/195 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH AS + + LL GAD +N
Sbjct: 250 NACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCH 309
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVD-CEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
+ +D+A + + + L + KG + +R A+V + + +L V + +T
Sbjct: 310 NKSAIDLAPTPQLKERL--AYEFKGHSLLQAAREADVTRI---KKHLSLE-MVNFKHPQT 363
Query: 121 GGTPLHVAAAKGY---IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH AAA Y + + LL A+ + E TPLH A+ + +++K
Sbjct: 364 HETALHCAAASPYPKRKQICELLLRK-GANINEKTKEFLTPLHVASEKAHNDVVEVVVKH 422
Query: 178 GADPHLKNYSGQTCL 192
A + + GQT L
Sbjct: 423 EAKVNALDNLGQTSL 437
Score = 56.0 bits (129), Expect = 4e-07
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLHVA+ K + DV + +++ A + +D G T LH AA G + LLL +G DP+
Sbjct: 402 TPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPN 460
Query: 183 LKNYSGQTCLDLVDPSISSWLEE 205
+ + G T L + + ++ L+E
Sbjct: 461 IISLQGFTALQMGNENVQQLLQE 483
Score = 55.2 bits (127), Expect = 6e-07
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE+L+ +GA+V D+ G PLH S G + LL GAD A + P+ A
Sbjct: 72 DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEA 131
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G + RN + T + A A V + K L +A
Sbjct: 132 AIKGKIDVC-IVLLQHGAE-PTIRNTDGRTALDLADPSA--KAVLTGEYKK--DELLESA 185
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
G + LL N + D TPLH AA + + + LLL+ GAD H K+
Sbjct: 186 RSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKD 241
Score = 48.0 bits (109), Expect = 9e-05
Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G DV + LL++ A+ D G PLH A +G E LLL+ GADP+
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 183 LKN 185
++
Sbjct: 119 ARD 121
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/162 (32%), Positives = 73/162 (45%), Gaps = 30/162 (18%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAVNY 60
AC + +++ V+ LVT VN D G TPLH A G + YLL++GA+V A +
Sbjct: 31 ACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDD 89
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G +P+ A S A+++ ++ G D N W Y
Sbjct: 90 GGLIPLHNACSFGHAEVVNLLL-RHGADPNARDN------------W---NY-------- 125
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ A+P + +G T L A
Sbjct: 126 --TPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGRTALDLA 164
>BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
protein.
Length = 1327
Score = 101 bits (241), Expect = 9e-21
Identities = 78/221 (35%), Positives = 110/221 (49%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 723 NACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRD 782
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCE--KSRNAEVDT 99
G P+D + E D + DLL QK+ + ++C + RN+
Sbjct: 783 GNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLH 842
Query: 100 LMS-----DAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
L + + E+ L +V GG PLH AA+ G++D+A L++ N + D
Sbjct: 843 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK-YNTCVNATDK 901
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA G+ + ALLL GADP +KN GQT LDL
Sbjct: 902 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 942
Score = 87.4 bits (207), Expect = 1e-16
Identities = 73/221 (33%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ GAD N DN +TPLH A G I + LL+ GAD N D
Sbjct: 255 NACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTD 314
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G+ +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 315 GKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLH 374
Query: 111 ---GYVEVRDL--------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY VR + K G PLH A + G+ +V + LL+ A + +D
Sbjct: 375 LAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH-GACVNAMDL 433
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL GADP L N G++ +D+
Sbjct: 434 WQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 474
Score = 75.8 bits (178), Expect = 4e-13
Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 32/236 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E L+ HGA VN D +TPLH AS + + LL GAD VN
Sbjct: 408 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCH 467
Query: 62 GELPVDIAESDAMAD----------LLQKVIDEKGVDCEKSRNAEVDTLMS-DAREWALH 110
G+ VD+A + + + LLQ + +K+ E+ + E ALH
Sbjct: 468 GKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALH 527
Query: 111 GYV--------EVRDL------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
V +V +L K TPLHVAA + + DV + L + A +
Sbjct: 528 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH-GAKMNA 586
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
+D G T LH AAL G + LLL +G+DP + + G T + + ++ L E+
Sbjct: 587 LDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSES 642
Score = 72.9 bits (171), Expect = 3e-12
Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L+ GA V + P+
Sbjct: 695 NRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPL 754
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + +E G +++DL G L
Sbjct: 755 HEAAAKGKYEIC-KLLLKHGADPTK-KNRDGNTPLDLVKE----GDTDIQDLLRGDAALL 808
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + + L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 809 DAAKKGCLARVQKLCTPENI--NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 866
Query: 185 NYSG 188
+ G
Sbjct: 867 DKGG 870
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/176 (31%), Positives = 83/176 (47%), Gaps = 12/176 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D++E L HGA +N D G T LH A G + R LL G+D + ++ G +
Sbjct: 572 DVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG 631
Query: 70 ESDAMADLLQK--VIDEKGVD---CEKSRNAEVDTLMSDAREWALHGYVEVRDLK-TGGT 123
++A+ +L + I VD E S+ +++T+ ++ V RDL+ T
Sbjct: 632 -NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETV----KQLCSSQNVNCRDLEGRHST 686
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
PLH AA + V + LL AD D G PLH A +G E A LL++ GA
Sbjct: 687 PLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGA 741
Score = 68.9 bits (161), Expect = 5e-11
Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V RD G PLH A + G+ +V LL ADP+ D +TPLH AA+ G+ +
Sbjct: 242 VHARD-DGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHEAAIKGKIDVCI 299
Query: 173 LLLKFGADPHLKNYSGQTCLDLVDPSISSWL-----EEAALKAPRRVNNNK 218
+LL+ GADP+++N G++ LDL DPS + L ++ L+A R N K
Sbjct: 300 VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEK 350
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 106 EWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAAL 164
E+ LH +V GG PLH A + G+ +VA+ L+ A + D +TPLH AA
Sbjct: 701 EYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH-GASVNVADLWKFTPLHEAAA 759
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
G+ E LLLK GADP KN G T LDLV
Sbjct: 760 KGKYEICKLLLKHGADPTKKNRDGNTPLDLV 790
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 6/179 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE L+ GA+V+ D+ G PLH S G + LL GAD A + P+ A
Sbjct: 230 DVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEA 289
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G D RN + + + A A V + K L AA
Sbjct: 290 AIKGKIDVC-IVLLQHGAD-PNIRNTDGKSALDLADPSA--KAVLTGEYKK--DELLEAA 343
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSG 188
G + LL N + D TPLH AA + + LLL+ GAD H K+ G
Sbjct: 344 RSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGG 402
Score = 48.8 bits (111), Expect = 5e-05
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++D+ L+ + VN D +TPLH A G + LL GAD N +G+ P+D
Sbjct: 882 HVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLD 941
Query: 68 IAESDAMADLL 78
+A +D + LL
Sbjct: 942 LATADDIRALL 952
Score = 46.0 bits (104), Expect = 4e-04
Identities = 50/184 (27%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ E L+ GA+VN + + TPLH A + L + GA + A++ G+ + A
Sbjct: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA- 598
Query: 71 SDAMADLLQ--KVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A+A LQ +++ G D + + ++A + L +R L
Sbjct: 599 --ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLE 656
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A G ++ K L N + C D EG TPLH AA + + LL GAD H K
Sbjct: 657 ASKA-GDLETVKQLCSSQNVN--CRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 713
Query: 185 NYSG 188
+ G
Sbjct: 714 DKGG 717
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
+PLH AA G DV + LL+ A+ D G PLH A +G E +LLL GADP+
Sbjct: 218 SPLHFAAGFGRKDVVEHLLQ-MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
Query: 183 LKN 185
++
Sbjct: 277 ARD 279
Score = 39.9 bits (89), Expect = 0.025
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 30/164 (18%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAV 58
+ AC + ++ V+ LV A+VN D G +PLH A G + +LL+ GA+V A
Sbjct: 187 LEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHAR 245
Query: 59 NYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ G +P+ A S A+++ ++ + G D N W Y
Sbjct: 246 DDGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDN------------W---NY------ 283
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ ADP+ + +G + L A
Sbjct: 284 ----TPLHEAAIKGKIDVCIVLLQH-GADPNIRNTDGKSALDLA 322
Score = 33.1 bits (72), Expect = 2.8
Identities = 18/61 (29%), Positives = 31/61 (50%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A G + K L++ N + + +PLH AA +G+K+ LL+ GA+ H ++
Sbjct: 189 ACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDG 248
Query: 188 G 188
G
Sbjct: 249 G 249
>AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1094
Score = 101 bits (241), Expect = 9e-21
Identities = 78/221 (35%), Positives = 110/221 (49%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 490 NACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRD 549
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCE--KSRNAEVDT 99
G P+D + E D + DLL QK+ + ++C + RN+
Sbjct: 550 GNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLH 609
Query: 100 LMS-----DAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
L + + E+ L +V GG PLH AA+ G++D+A L++ N + D
Sbjct: 610 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK-YNTCVNATDK 668
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA G+ + ALLL GADP +KN GQT LDL
Sbjct: 669 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 709
Score = 87.4 bits (207), Expect = 1e-16
Identities = 73/221 (33%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ GAD N DN +TPLH A G I + LL+ GAD N D
Sbjct: 22 NACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTD 81
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G+ +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 82 GKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLH 141
Query: 111 ---GYVEVRDL--------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY VR + K G PLH A + G+ +V + LL+ A + +D
Sbjct: 142 LAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH-GACVNAMDL 200
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL GADP L N G++ +D+
Sbjct: 201 WQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 241
Score = 75.8 bits (178), Expect = 4e-13
Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 32/236 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E L+ HGA VN D +TPLH AS + + LL GAD VN
Sbjct: 175 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCH 234
Query: 62 GELPVDIAESDAMAD----------LLQKVIDEKGVDCEKSRNAEVDTLMS-DAREWALH 110
G+ VD+A + + + LLQ + +K+ E+ + E ALH
Sbjct: 235 GKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALH 294
Query: 111 GYV--------EVRDL------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
V +V +L K TPLHVAA + + DV + L + A +
Sbjct: 295 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH-GAKMNA 353
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
+D G T LH AAL G + LLL +G+DP + + G T + + ++ L E+
Sbjct: 354 LDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSES 409
Score = 72.9 bits (171), Expect = 3e-12
Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L+ GA V + P+
Sbjct: 462 NRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPL 521
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + +E G +++DL G L
Sbjct: 522 HEAAAKGKYEIC-KLLLKHGADPTK-KNRDGNTPLDLVKE----GDTDIQDLLKGDAALL 575
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + + L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 576 DAAKKGCLARVQKLCTPENI--NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 633
Query: 185 NYSG 188
+ G
Sbjct: 634 DKGG 637
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/176 (31%), Positives = 83/176 (47%), Gaps = 12/176 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D++E L HGA +N D G T LH A G + R LL G+D + ++ G +
Sbjct: 339 DVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG 398
Query: 70 ESDAMADLLQK--VIDEKGVD---CEKSRNAEVDTLMSDAREWALHGYVEVRDLK-TGGT 123
++A+ +L + I VD E S+ +++T+ ++ V RDL+ T
Sbjct: 399 -NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETV----KQLCSSQNVNCRDLEGRHST 453
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
PLH AA + V + LL AD D G PLH A +G E A LL++ GA
Sbjct: 454 PLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGA 508
Score = 68.9 bits (161), Expect = 5e-11
Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V RD G PLH A + G+ +V LL ADP+ D +TPLH AA+ G+ +
Sbjct: 9 VHARD-DGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHEAAIKGKIDVCI 66
Query: 173 LLLKFGADPHLKNYSGQTCLDLVDPSISSWL-----EEAALKAPRRVNNNK 218
+LL+ GADP+++N G++ LDL DPS + L ++ L+A R N K
Sbjct: 67 VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEK 117
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 106 EWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAAL 164
E+ LH +V GG PLH A + G+ +VA+ L+ A + D +TPLH AA
Sbjct: 468 EYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH-GASVNVADLWKFTPLHEAAA 526
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
G+ E LLLK GADP KN G T LDLV
Sbjct: 527 KGKYEICKLLLKHGADPTKKNRDGNTPLDLV 557
Score = 48.8 bits (111), Expect = 5e-05
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++D+ L+ + VN D +TPLH A G + LL GAD N +G+ P+D
Sbjct: 649 HVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLD 708
Query: 68 IAESDAMADLL 78
+A +D + LL
Sbjct: 709 LATADDIRALL 719
Score = 48.4 bits (110), Expect = 7e-05
Identities = 52/174 (29%), Positives = 72/174 (41%), Gaps = 6/174 (3%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ GA+V+ D+ G PLH S G + LL GAD A + P+ A
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK 61
Query: 75 ADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYI 134
D+ V+ + G D RN + + + A A V + K L AA G
Sbjct: 62 IDVCI-VLLQHGAD-PNIRNTDGKSALDLADPSAKA--VLTGEYKKD--ELLEAARSGNE 115
Query: 135 DVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSG 188
+ LL N + D TPLH AA + + LLL+ GAD H K+ G
Sbjct: 116 EKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGG 169
Score = 46.0 bits (104), Expect = 4e-04
Identities = 50/184 (27%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ E L+ GA+VN + + TPLH A + L + GA + A++ G+ + A
Sbjct: 307 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA- 365
Query: 71 SDAMADLLQ--KVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A+A LQ +++ G D + + ++A + L +R L
Sbjct: 366 --ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLE 423
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A G ++ K L N + C D EG TPLH AA + + LL GAD H K
Sbjct: 424 ASKA-GDLETVKQLCSSQNVN--CRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 480
Query: 185 NYSG 188
+ G
Sbjct: 481 DKGG 484
>AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 101 bits (241), Expect = 9e-21
Identities = 78/221 (35%), Positives = 110/221 (49%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 723 NACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRD 782
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCE--KSRNAEVDT 99
G P+D + E D + DLL QK+ + ++C + RN+
Sbjct: 783 GNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLH 842
Query: 100 LMS-----DAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
L + + E+ L +V GG PLH AA+ G++D+A L++ N + D
Sbjct: 843 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK-YNTCVNATDK 901
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA G+ + ALLL GADP +KN GQT LDL
Sbjct: 902 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 942
Score = 87.4 bits (207), Expect = 1e-16
Identities = 73/221 (33%), Positives = 108/221 (48%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++V L+ GAD N DN +TPLH A G I + LL+ GAD N D
Sbjct: 255 NACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTD 314
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH 110
G+ +D+A+ A A L + ++ ++ +S N E V+ SD R+ LH
Sbjct: 315 GKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLH 374
Query: 111 ---GYVEVRDL--------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
GY VR + K G PLH A + G+ +V + LL+ A + +D
Sbjct: 375 LAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKH-GACVNAMDL 433
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA + E +LLL GADP L N G++ +D+
Sbjct: 434 WQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 474
Score = 75.8 bits (178), Expect = 4e-13
Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 32/236 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E L+ HGA VN D +TPLH AS + + LL GAD VN
Sbjct: 408 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCH 467
Query: 62 GELPVDIAESDAMAD----------LLQKVIDEKGVDCEKSRNAEVDTLMS-DAREWALH 110
G+ VD+A + + + LLQ + +K+ E+ + E ALH
Sbjct: 468 GKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALH 527
Query: 111 GYV--------EVRDL------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
V +V +L K TPLHVAA + + DV + L + A +
Sbjct: 528 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH-GAKMNA 586
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
+D G T LH AAL G + LLL +G+DP + + G T + + ++ L E+
Sbjct: 587 LDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSES 642
Score = 72.9 bits (171), Expect = 3e-12
Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L+ GA V + P+
Sbjct: 695 NRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPL 754
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + +E G +++DL G L
Sbjct: 755 HEAAAKGKYEIC-KLLLKHGADPTK-KNRDGNTPLDLVKE----GDTDIQDLLKGDAALL 808
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + + L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 809 DAAKKGCLARVQKLCTPENI--NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 866
Query: 185 NYSG 188
+ G
Sbjct: 867 DKGG 870
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/176 (31%), Positives = 83/176 (47%), Gaps = 12/176 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D++E L HGA +N D G T LH A G + R LL G+D + ++ G +
Sbjct: 572 DVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG 631
Query: 70 ESDAMADLLQK--VIDEKGVD---CEKSRNAEVDTLMSDAREWALHGYVEVRDLK-TGGT 123
++A+ +L + I VD E S+ +++T+ ++ V RDL+ T
Sbjct: 632 -NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETV----KQLCSSQNVNCRDLEGRHST 686
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
PLH AA + V + LL AD D G PLH A +G E A LL++ GA
Sbjct: 687 PLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGA 741
Score = 68.9 bits (161), Expect = 5e-11
Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 7/111 (6%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V RD G PLH A + G+ +V LL ADP+ D +TPLH AA+ G+ +
Sbjct: 242 VHARD-DGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHEAAIKGKIDVCI 299
Query: 173 LLLKFGADPHLKNYSGQTCLDLVDPSISSWL-----EEAALKAPRRVNNNK 218
+LL+ GADP+++N G++ LDL DPS + L ++ L+A R N K
Sbjct: 300 VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEK 350
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 106 EWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAAL 164
E+ LH +V GG PLH A + G+ +VA+ L+ A + D +TPLH AA
Sbjct: 701 EYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH-GASVNVADLWKFTPLHEAAA 759
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
G+ E LLLK GADP KN G T LDLV
Sbjct: 760 KGKYEICKLLLKHGADPTKKNRDGNTPLDLV 790
Score = 54.4 bits (125), Expect = 1e-06
Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 6/179 (3%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE L+ GA+V+ D+ G PLH S G + LL GAD A + P+ A
Sbjct: 230 DVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEA 289
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D+ V+ + G D RN + + + A A V + K L AA
Sbjct: 290 AIKGKIDVC-IVLLQHGAD-PNIRNTDGKSALDLADPSA--KAVLTGEYKK--DELLEAA 343
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSG 188
G + LL N + D TPLH AA + + LLL+ GAD H K+ G
Sbjct: 344 RSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGG 402
Score = 48.8 bits (111), Expect = 5e-05
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++D+ L+ + VN D +TPLH A G + LL GAD N +G+ P+D
Sbjct: 882 HVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLD 941
Query: 68 IAESDAMADLL 78
+A +D + LL
Sbjct: 942 LATADDIRALL 952
Score = 46.0 bits (104), Expect = 4e-04
Identities = 50/184 (27%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ E L+ GA+VN + + TPLH A + L + GA + A++ G+ + A
Sbjct: 540 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA- 598
Query: 71 SDAMADLLQ--KVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A+A LQ +++ G D + + ++A + L +R L
Sbjct: 599 --ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLE 656
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A G ++ K L N + C D EG TPLH AA + + LL GAD H K
Sbjct: 657 ASKA-GDLETVKQLCSSQNVN--CRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 713
Query: 185 NYSG 188
+ G
Sbjct: 714 DKGG 717
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
+PLH AA G DV + LL+ A+ D G PLH A +G E +LLL GADP+
Sbjct: 218 SPLHFAAGFGRKDVVEHLLQ-MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
Query: 183 LKN 185
++
Sbjct: 277 ARD 279
Score = 39.9 bits (89), Expect = 0.025
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 30/164 (18%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGW--TPLHATASCGFISIARYLLESGADVAAV 58
+ AC + ++ V+ LV A+VN D G +PLH A G + +LL+ GA+V A
Sbjct: 187 LEACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHAR 245
Query: 59 NYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ G +P+ A S A+++ ++ + G D N W Y
Sbjct: 246 DDGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDN------------W---NY------ 283
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
TPLH AA KG IDV LL+ ADP+ + +G + L A
Sbjct: 284 ----TPLHEAAIKGKIDVCIVLLQH-GADPNIRNTDGKSALDLA 322
Score = 33.1 bits (72), Expect = 2.8
Identities = 18/61 (29%), Positives = 31/61 (50%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A G + K L++ N + + +PLH AA +G+K+ LL+ GA+ H ++
Sbjct: 189 ACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDG 248
Query: 188 G 188
G
Sbjct: 249 G 249
>AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
variant protein.
Length = 1055
Score = 101 bits (241), Expect = 9e-21
Identities = 78/221 (35%), Positives = 110/221 (49%), Gaps = 29/221 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E LV HGA VN D +TPLH A+ G I + LL+ GAD N D
Sbjct: 451 NACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRD 510
Query: 62 GELPVD-IAESDA-MADLL------------------QKVIDEKGVDCE--KSRNAEVDT 99
G P+D + E D + DLL QK+ + ++C + RN+
Sbjct: 511 GNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLH 570
Query: 100 LMS-----DAREWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDY 153
L + + E+ L +V GG PLH AA+ G++D+A L++ N + D
Sbjct: 571 LAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIK-YNTCVNATDK 629
Query: 154 EGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+TPLH AA G+ + ALLL GADP +KN GQT LDL
Sbjct: 630 WAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 670
Score = 77.4 bits (182), Expect = 1e-13
Identities = 68/203 (33%), Positives = 98/203 (48%), Gaps = 29/203 (14%)
Query: 20 ADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQ 79
AD N DN +TPLH A G I + LL+ GAD N DG+ +D+A+ A A L
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTG 60
Query: 80 KVIDEKGVDCEKSRNAE----------VDTLMSDARE-WALH---GYVEVRDL------- 118
+ ++ ++ +S N E V+ SD R+ LH GY VR +
Sbjct: 61 EYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHG 120
Query: 119 -------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G PLH A + G+ +V + LL+ A + +D +TPLH AA + E
Sbjct: 121 ADVHAKDKGGLVPLHNACSYGHYEVTELLLKH-GACVNAMDLWQFTPLHEAASKNRVEVC 179
Query: 172 ALLLKFGADPHLKNYSGQTCLDL 194
+LLL GADP L N G++ +D+
Sbjct: 180 SLLLSHGADPTLVNCHGKSAVDM 202
Score = 75.8 bits (178), Expect = 4e-13
Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 32/236 (13%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+AC + ++ E L+ HGA VN D +TPLH AS + + LL GAD VN
Sbjct: 136 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCH 195
Query: 62 GELPVDIAESDAMAD----------LLQKVIDEKGVDCEKSRNAEVDTLMS-DAREWALH 110
G+ VD+A + + + LLQ + +K+ E+ + E ALH
Sbjct: 196 GKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALH 255
Query: 111 GYV--------EVRDL------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
V +V +L K TPLHVAA + + DV + L + A +
Sbjct: 256 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH-GAKMNA 314
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
+D G T LH AAL G + LLL +G+DP + + G T + + ++ L E+
Sbjct: 315 LDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSES 370
Score = 72.9 bits (171), Expect = 3e-12
Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 10/184 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+ + +VE+L+ HGADV+ D G PLH S G +A L+ GA V + P+
Sbjct: 423 NRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPL 482
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A + ++ K++ + G D K +N + +T + +E G +++DL G L
Sbjct: 483 HEAAAKGKYEIC-KLLLKHGADPTK-KNRDGNTPLDLVKE----GDTDIQDLLRGDAALL 536
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEG--WTPLHAAALWGQKEAAALLLKFGADPHLK 184
AA KG + + L N +C D +G TPLH AA + E A LL+ GAD + +
Sbjct: 537 DAAKKGCLARVQKLCTPENI--NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 594
Query: 185 NYSG 188
+ G
Sbjct: 595 DKGG 598
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/176 (31%), Positives = 83/176 (47%), Gaps = 12/176 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D++E L HGA +N D G T LH A G + R LL G+D + ++ G +
Sbjct: 300 DVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMG 359
Query: 70 ESDAMADLLQK--VIDEKGVD---CEKSRNAEVDTLMSDAREWALHGYVEVRDLK-TGGT 123
++A+ +L + I VD E S+ +++T+ ++ V RDL+ T
Sbjct: 360 -NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETV----KQLCSSQNVNCRDLEGRHST 414
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
PLH AA + V + LL AD D G PLH A +G E A LL++ GA
Sbjct: 415 PLHFAAGYNRVSVVEYLLHH-GADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGA 469
Score = 64.9 bits (151), Expect = 8e-10
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 106 EWALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAAL 164
E+ LH +V GG PLH A + G+ +VA+ L+ A + D +TPLH AA
Sbjct: 429 EYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRH-GASVNVADLWKFTPLHEAAA 487
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
G+ E LLLK GADP KN G T LDLV
Sbjct: 488 KGKYEICKLLLKHGADPTKKNRDGNTPLDLV 518
Score = 58.8 bits (136), Expect = 5e-08
Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Query: 146 ADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWL-- 203
ADP+ D +TPLH AA+ G+ + +LL+ GADP+++N G++ LDL DPS + L
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTG 60
Query: 204 ---EEAALKAPRRVNNNK 218
++ L+A R N K
Sbjct: 61 EYKKDELLEAARSGNEEK 78
Score = 48.8 bits (111), Expect = 5e-05
Identities = 24/71 (33%), Positives = 37/71 (52%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++D+ L+ + VN D +TPLH A G + LL GAD N +G+ P+D
Sbjct: 610 HVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLD 669
Query: 68 IAESDAMADLL 78
+A +D + LL
Sbjct: 670 LATADDIRALL 680
Score = 46.0 bits (104), Expect = 4e-04
Identities = 50/184 (27%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ E L+ GA+VN + + TPLH A + L + GA + A++ G+ + A
Sbjct: 268 VTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRA- 326
Query: 71 SDAMADLLQ--KVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
A+A LQ +++ G D + + ++A + L +R L
Sbjct: 327 --ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLE 384
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A G ++ K L N + C D EG TPLH AA + + LL GAD H K
Sbjct: 385 ASKA-GDLETVKQLCSSQNVN--CRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 441
Query: 185 NYSG 188
+ G
Sbjct: 442 DKGG 445
Score = 41.5 bits (93), Expect = 0.008
Identities = 20/49 (40%), Positives = 28/49 (57%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
+V+ L+ HGADV+ D G PLH S G + LL+ GA V A++
Sbjct: 112 IVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 160
Score = 32.3 bits (70), Expect = 4.9
Identities = 17/56 (30%), Positives = 27/56 (48%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
++ L + + D TPLH A + I + LL+ GADV A + G +P+
Sbjct: 79 LMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPL 134
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 66 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 125
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 126 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 184
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 185 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 243
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 244 SPHAAAKNGYTPLHI 258
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 28 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 87
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 88 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 146
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 147 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 205
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 206 LQKSASPDAAGKSGLTPL 223
Score = 71.7 bits (168), Expect = 7e-12
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 230 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 289
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH---------GYVEVRD 117
+A + D++ ++ + + S + + L A+E ++ +V+ +
Sbjct: 290 HLAAQEGHVDMVSLLLG-RNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ- 347
Query: 118 LKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K G TPLHV G I + LL+ +A + G+TPLH AA G +LL+
Sbjct: 348 TKMGYTPLHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 406
Query: 178 GADPHLKNYSGQTCLDL 194
A P+ +G T L +
Sbjct: 407 NASPNELTVNGNTALGI 423
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 75 ADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGTPLHV 127
+++ +++ + V E + + + ++ + + +V K TPLH+
Sbjct: 67 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 126
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
+A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 127 SARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKK 185
Query: 188 GQTCL 192
G T L
Sbjct: 186 GFTPL 190
Score = 51.6 bits (118), Expect = 8e-06
Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 21 GFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 79
Query: 181 PHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 80 PNTTNVRGETALHM 93
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 325 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 384
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 385 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 434
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 9/146 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++DMV L+ A+VN + G TPLH A +++A L+ GA V A G
Sbjct: 292 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 351
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEV 115
P+ + ++ ++ K++N L A++ H
Sbjct: 352 YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG-YTPLHQAAQQGHTHIINVLLQNNASP 410
Query: 116 RDLK-TGGTPLHVAAAKGYIDVAKTL 140
+L G T L +A GYI V TL
Sbjct: 411 NELTVNGNTALGIARRLGYISVVDTL 436
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 504
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 505 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 563
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 622
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 623 SPHAAAKNGYTPLHI 637
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 466
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 467 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 525
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 585 LQKSASPDAAGKSGLTPL 602
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/226 (29%), Positives = 102/226 (45%), Gaps = 7/226 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LVT+GA+VN G+TPL+ A + + ++LL++GA + DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDL 118
P+ +A ++ +++ + + D + AL +V +
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV-ES 232
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K+G TPLH+AA G I+VA TLL + A D TPLH A+ G LLL G
Sbjct: 233 KSGFTPLHIAAHYGNINVA-TLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 179 ADPHLKNYSGQTCLDLVDPSISSWLEEAAL-KAPRRVNNNKRKLSP 223
A K G T L S + E L +A ++ K LSP
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Score = 71.7 bits (168), Expect = 7e-12
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 609 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 668
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH---------GYVEVRD 117
+A + D++ ++ + + S + + L A+E ++ +V+ +
Sbjct: 669 HLAAQEGHVDMVSLLLG-RNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ- 726
Query: 118 LKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K G TPLHV G I + LL+ +A + G+TPLH AA G +LL+
Sbjct: 727 TKMGYTPLHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 785
Query: 178 GADPHLKNYSGQTCLDL 194
A P+ +G T L +
Sbjct: 786 NASPNELTVNGNTALGI 802
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/195 (27%), Positives = 84/195 (43%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ GA ++ +G TPLH A G + LL+ A + + +G P+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT------- 120
+A + +Q ++ + V + N + L A + D K
Sbjct: 340 MATQGDHLNCVQLLL-QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKAL 398
Query: 121 -GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 180 DPHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 458 SPNTTNVRGETALHM 472
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 27/188 (14%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+L+ V+ L+ H V+ N+ T LH A CG +A+ LL+ A+ A +G P+
Sbjct: 345 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL 404
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ HG ++G TP+H
Sbjct: 405 HIA-------------------CKKNRIKVMELLLK-------HGASIQAVTESGLTPIH 438
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
VAA G++++ L+ A P+ + G T LH AA GQ E L++ GA K
Sbjct: 439 VAAFMGHVNIVSQLMHH-GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 187 SGQTCLDL 194
QT L +
Sbjct: 498 DDQTPLHI 505
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 8/189 (4%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ + L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAA 441
Query: 71 SDAMADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGT 123
+++ +++ + V E + + + ++ + + +V K T
Sbjct: 442 FMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH++A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 502 PLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560
Query: 184 KNYSGQTCL 192
G T L
Sbjct: 561 TTKKGFTPL 569
Score = 55.6 bits (128), Expect = 5e-07
Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 12/185 (6%)
Query: 18 HGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADL 77
+ ADV G+TPLH A G I++A LL A V + P+ +A A++
Sbjct: 226 NNADVE--SKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 78 LQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD-LKTGGTPLHVAA 129
++ ++D +G + + L AR E L + K G +PLH+A
Sbjct: 284 VKLLLD-RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+++ + LL+ N D V + T LH AA G + A +LL A+P+ K +G
Sbjct: 343 QGDHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Query: 190 TCLDL 194
T L +
Sbjct: 402 TPLHI 406
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/177 (24%), Positives = 82/177 (46%), Gaps = 4/177 (2%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++++V L+ A+V+ +G T LH + G + + L+ +GA+V A + +G P
Sbjct: 84 EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTP 143
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRN--AEVDTLMSDAREWALHGYVEVRDLKTGGT 123
+ +A + ++++ ++D + + + + + + +E
Sbjct: 144 LYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRL 203
Query: 124 P-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
P LH+AA K A LL++ N + D G+TPLH AA +G A LLL A
Sbjct: 204 PALHIAARKDDTKAAALLLQNDN-NADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 14/187 (7%)
Query: 16 VTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
+ +G D+N + G LH + G + + LL+ A+V A G + IA A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL--------HGYVEVRDLKTGGTPLHV 127
+++ KV+ G + L A+E L +G + + G TPL V
Sbjct: 121 EVV-KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAV 179
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A +G+ V LLE+ D LH AA +AAALLL+ + +++ S
Sbjct: 180 ALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKS 234
Query: 188 GQTCLDL 194
G T L +
Sbjct: 235 GFTPLHI 241
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 704 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 763
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 764 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 813
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 9/146 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++DMV L+ A+VN + G TPLH A +++A L+ GA V A G
Sbjct: 671 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 730
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEV 115
P+ + ++ ++ K++N L A++ H
Sbjct: 731 YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG-YTPLHQAAQQGHTHIINVLLQNNASP 789
Query: 116 RDLK-TGGTPLHVAAAKGYIDVAKTL 140
+L G T L +A GYI V TL
Sbjct: 790 NELTVNGNTALGIARRLGYISVVDTL 815
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 504
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 505 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 563
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 622
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 623 SPHAAAKNGYTPLHI 637
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 466
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 467 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 525
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 585 LQKSASPDAAGKSGLTPL 602
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/226 (29%), Positives = 102/226 (45%), Gaps = 7/226 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LVT+GA+VN G+TPL+ A + + ++LL++GA + DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDL 118
P+ +A ++ +++ + + D + AL +V +
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV-ES 232
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K+G TPLH+AA G I+VA TLL + A D TPLH A+ G LLL G
Sbjct: 233 KSGFTPLHIAAHYGNINVA-TLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 179 ADPHLKNYSGQTCLDLVDPSISSWLEEAAL-KAPRRVNNNKRKLSP 223
A K G T L S + E L +A ++ K LSP
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Score = 71.7 bits (168), Expect = 7e-12
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 609 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 668
Query: 67 DIAESDAMADLLQKVIDEKG--VDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP 124
+A + D++ ++ A + ++ A G K G TP
Sbjct: 669 HLAAQEGHVDMVSLLLGRNANVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 728
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHV G I + LL+ +A + G+TPLH AA G +LL+ A P+
Sbjct: 729 LHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 787
Query: 185 NYSGQTCLDL 194
+G T L +
Sbjct: 788 TVNGNTALGI 797
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/195 (27%), Positives = 84/195 (43%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ GA ++ +G TPLH A G + LL+ A + + +G P+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT------- 120
+A + +Q ++ + V + N + L A + D K
Sbjct: 340 MATQGDHLNCVQLLL-QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKAL 398
Query: 121 -GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 180 DPHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 458 SPNTTNVRGETALHM 472
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 27/188 (14%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+L+ V+ L+ H V+ N+ T LH A CG +A+ LL+ A+ A +G P+
Sbjct: 345 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL 404
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ HG ++G TP+H
Sbjct: 405 HIA-------------------CKKNRIKVMELLLK-------HGASIQAVTESGLTPIH 438
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
VAA G++++ L+ A P+ + G T LH AA GQ E L++ GA K
Sbjct: 439 VAAFMGHVNIVSQLMHH-GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 187 SGQTCLDL 194
QT L +
Sbjct: 498 DDQTPLHI 505
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 8/189 (4%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ + L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAA 441
Query: 71 SDAMADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGT 123
+++ +++ + V E + + + ++ + + +V K T
Sbjct: 442 FMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH++A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 502 PLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560
Query: 184 KNYSGQTCL 192
G T L
Sbjct: 561 TTKKGFTPL 569
Score = 55.6 bits (128), Expect = 5e-07
Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 12/185 (6%)
Query: 18 HGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADL 77
+ ADV G+TPLH A G I++A LL A V + P+ +A A++
Sbjct: 226 NNADVE--SKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 78 LQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD-LKTGGTPLHVAA 129
++ ++D +G + + L AR E L + K G +PLH+A
Sbjct: 284 VKLLLD-RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+++ + LL+ N D V + T LH AA G + A +LL A+P+ K +G
Sbjct: 343 QGDHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Query: 190 TCLDL 194
T L +
Sbjct: 402 TPLHI 406
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/177 (24%), Positives = 82/177 (46%), Gaps = 4/177 (2%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++++V L+ A+V+ +G T LH + G + + L+ +GA+V A + +G P
Sbjct: 84 EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTP 143
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRN--AEVDTLMSDAREWALHGYVEVRDLKTGGT 123
+ +A + ++++ ++D + + + + + + +E
Sbjct: 144 LYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRL 203
Query: 124 P-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
P LH+AA K A LL++ N + D G+TPLH AA +G A LLL A
Sbjct: 204 PALHIAARKDDTKAAALLLQNDN-NADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 14/187 (7%)
Query: 16 VTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
+ +G D+N + G LH + G + + LL+ A+V A G + IA A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL--------HGYVEVRDLKTGGTPLHV 127
+++ KV+ G + L A+E L +G + + G TPL V
Sbjct: 121 EVV-KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAV 179
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A +G+ V LLE+ D LH AA +AAALLL+ + +++ S
Sbjct: 180 ALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKS 234
Query: 188 GQTCLDL 194
G T L +
Sbjct: 235 GFTPLHI 241
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 758
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 759 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 808
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 60 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 119
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 120 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 178
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 179 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 237
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 238 SPHAAAKNGYTPLHI 252
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 22 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 81
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 82 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 140
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 141 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 199
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 200 LQKSASPDAAGKSGLTPL 217
Score = 71.7 bits (168), Expect = 7e-12
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 224 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 283
Query: 67 DIAESDAMADLLQKVIDEKG--VDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP 124
+A + D++ ++ A + ++ A G K G TP
Sbjct: 284 HLAAQEGHVDMVSLLLGRNANVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 343
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHV G I + LL+ +A + G+TPLH AA G +LL+ A P+
Sbjct: 344 LHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 402
Query: 185 NYSGQTCLDL 194
+G T L +
Sbjct: 403 TVNGNTALGI 412
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 75 ADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGTPLHV 127
+++ +++ + V E + + + ++ + + +V K TPLH+
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
+A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 121 SARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKK 179
Query: 188 GQTCL 192
G T L
Sbjct: 180 GFTPL 184
Score = 51.6 bits (118), Expect = 8e-06
Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 15 GFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 181 PHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 74 PNTTNVRGETALHM 87
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 314 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 373
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 374 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 423
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 504
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 505 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 563
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 622
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 623 SPHAAAKNGYTPLHI 637
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 466
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 467 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 525
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 585 LQKSASPDAAGKSGLTPL 602
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/226 (29%), Positives = 102/226 (45%), Gaps = 7/226 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LVT+GA+VN G+TPL+ A + + ++LL++GA + DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDL 118
P+ +A ++ +++ + + D + AL +V +
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV-ES 232
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K+G TPLH+AA G I+VA TLL + A D TPLH A+ G LLL G
Sbjct: 233 KSGFTPLHIAAHYGNINVA-TLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 179 ADPHLKNYSGQTCLDLVDPSISSWLEEAAL-KAPRRVNNNKRKLSP 223
A K G T L S + E L +A ++ K LSP
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Score = 71.7 bits (168), Expect = 7e-12
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 609 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 668
Query: 67 DIAESDAMADLLQKVIDEKG--VDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP 124
+A + D++ ++ A + ++ A G K G TP
Sbjct: 669 HLAAQEGHVDMVSLLLGRNANVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 728
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHV G I + LL+ +A + G+TPLH AA G +LL+ A P+
Sbjct: 729 LHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 787
Query: 185 NYSGQTCLDL 194
+G T L +
Sbjct: 788 TVNGNTALGI 797
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/195 (27%), Positives = 84/195 (43%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ GA ++ +G TPLH A G + LL+ A + + +G P+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT------- 120
+A + +Q ++ + V + N + L A + D K
Sbjct: 340 MATQGDHLNCVQLLL-QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKAL 398
Query: 121 -GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 180 DPHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 458 SPNTTNVRGETALHM 472
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 27/188 (14%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+L+ V+ L+ H V+ N+ T LH A CG +A+ LL+ A+ A +G P+
Sbjct: 345 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL 404
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ HG ++G TP+H
Sbjct: 405 HIA-------------------CKKNRIKVMELLLK-------HGASIQAVTESGLTPIH 438
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
VAA G++++ L+ A P+ + G T LH AA GQ E L++ GA K
Sbjct: 439 VAAFMGHVNIVSQLMHH-GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 187 SGQTCLDL 194
QT L +
Sbjct: 498 DDQTPLHI 505
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 8/189 (4%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ + L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAA 441
Query: 71 SDAMADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGT 123
+++ +++ + V E + + + ++ + + +V K T
Sbjct: 442 FMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH++A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 502 PLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560
Query: 184 KNYSGQTCL 192
G T L
Sbjct: 561 TTKKGFTPL 569
Score = 55.6 bits (128), Expect = 5e-07
Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 12/185 (6%)
Query: 18 HGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADL 77
+ ADV G+TPLH A G I++A LL A V + P+ +A A++
Sbjct: 226 NNADVE--SKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 78 LQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD-LKTGGTPLHVAA 129
++ ++D +G + + L AR E L + K G +PLH+A
Sbjct: 284 VKLLLD-RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+++ + LL+ N D V + T LH AA G + A +LL A+P+ K +G
Sbjct: 343 QGDHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Query: 190 TCLDL 194
T L +
Sbjct: 402 TPLHI 406
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/177 (24%), Positives = 82/177 (46%), Gaps = 4/177 (2%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++++V L+ A+V+ +G T LH + G + + L+ +GA+V A + +G P
Sbjct: 84 EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTP 143
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRN--AEVDTLMSDAREWALHGYVEVRDLKTGGT 123
+ +A + ++++ ++D + + + + + + +E
Sbjct: 144 LYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRL 203
Query: 124 P-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
P LH+AA K A LL++ N + D G+TPLH AA +G A LLL A
Sbjct: 204 PALHIAARKDDTKAAALLLQNDN-NADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 14/187 (7%)
Query: 16 VTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
+ +G D+N + G LH + G + + LL+ A+V A G + IA A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL--------HGYVEVRDLKTGGTPLHV 127
+++ KV+ G + L A+E L +G + + G TPL V
Sbjct: 121 EVV-KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAV 179
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A +G+ V LLE+ D LH AA +AAALLL+ + +++ S
Sbjct: 180 ALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKS 234
Query: 188 GQTCLDL 194
G T L +
Sbjct: 235 GFTPLHI 241
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 758
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 759 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 808
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 60 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 119
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 120 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 178
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 179 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 237
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 238 SPHAAAKNGYTPLHI 252
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 22 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 81
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 82 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 140
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 141 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 199
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 200 LQKSASPDAAGKSGLTPL 217
Score = 71.7 bits (168), Expect = 7e-12
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 224 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 283
Query: 67 DIAESDAMADLLQKVIDEKG--VDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP 124
+A + D++ ++ A + ++ A G K G TP
Sbjct: 284 HLAAQEGHVDMVSLLLGRNANVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 343
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHV G I + LL+ +A + G+TPLH AA G +LL+ A P+
Sbjct: 344 LHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 402
Query: 185 NYSGQTCLDL 194
+G T L +
Sbjct: 403 TVNGNTALGI 412
Score = 67.3 bits (157), Expect = 1e-10
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 75 ADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGTPLHV 127
+++ +++ + V E + + + ++ + + +V K TPLH+
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHI 120
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
+A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 121 SARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKK 179
Query: 188 GQTCL 192
G T L
Sbjct: 180 GFTPL 184
Score = 51.6 bits (118), Expect = 8e-06
Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 15 GFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 181 PHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 74 PNTTNVRGETALHM 87
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 314 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 373
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 374 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 423
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 98.3 bits (234), Expect = 7e-20
Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V L+ HGA N + G T LH A G + RYL++ GA V A D + P+
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 504
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLK 119
I+ AD++Q+++ ++G + + L ARE + L HG K
Sbjct: 505 ISARLGKADIVQQLL-QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTK 563
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G ++VA LL+ +A PD G TPLH AA + ++ A LLL GA
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 622
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 623 SPHAAAKNGYTPLHI 637
Score = 89.0 bits (211), Expect = 4e-17
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E L+ HGA + G TP+H A G ++I L+ GA N G
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 466
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWALHGYVE 114
E + +A A++++ ++ + G E + L AR + G
Sbjct: 467 ETALHMAARSGQAEVVRYLVQD-GAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 525
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+G TPLH++A +G+ DVA LL D A +G+TPLH AA +G+ E A LL
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLL-DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P SG T L
Sbjct: 585 LQKSASPDAAGKSGLTPL 602
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/226 (29%), Positives = 102/226 (45%), Gaps = 7/226 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LVT+GA+VN G+TPL+ A + + ++LL++GA + DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDL 118
P+ +A ++ +++ + + D + AL +V +
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV-ES 232
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K+G TPLH+AA G I+VA TLL + A D TPLH A+ G LLL G
Sbjct: 233 KSGFTPLHIAAHYGNINVA-TLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 179 ADPHLKNYSGQTCLDLVDPSISSWLEEAAL-KAPRRVNNNKRKLSP 223
A K G T L S + E L +A ++ K LSP
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSP 337
Score = 71.7 bits (168), Expect = 7e-12
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 3/190 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 609 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 668
Query: 67 DIAESDAMADLLQKVIDEKG--VDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP 124
+A + D++ ++ A + ++ A G K G TP
Sbjct: 669 HLAAQEGHVDMVSLLLGRNANVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 728
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHV G I + LL+ +A + G+TPLH AA G +LL+ A P+
Sbjct: 729 LHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 787
Query: 185 NYSGQTCLDL 194
+G T L +
Sbjct: 788 TVNGNTALGI 797
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/195 (27%), Positives = 84/195 (43%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ GA ++ +G TPLH A G + LL+ A + + +G P+
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT------- 120
+A + +Q ++ + V + N + L A + D K
Sbjct: 340 MATQGDHLNCVQLLL-QHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKAL 398
Query: 121 -GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + LL+ A V G TP+H AA G + L+ GA
Sbjct: 399 NGFTPLHIACKKNRIKVMELLLKH-GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 180 DPHLKNYSGQTCLDL 194
P+ N G+T L +
Sbjct: 458 SPNTTNVRGETALHM 472
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 27/188 (14%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+L+ V+ L+ H V+ N+ T LH A CG +A+ LL+ A+ A +G P+
Sbjct: 345 DHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL 404
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ HG ++G TP+H
Sbjct: 405 HIA-------------------CKKNRIKVMELLLK-------HGASIQAVTESGLTPIH 438
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
VAA G++++ L+ A P+ + G T LH AA GQ E L++ GA K
Sbjct: 439 VAAFMGHVNIVSQLMHH-GASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 187 SGQTCLDL 194
QT L +
Sbjct: 498 DDQTPLHI 505
Score = 67.7 bits (158), Expect = 1e-10
Identities = 49/189 (25%), Positives = 85/189 (44%), Gaps = 8/189 (4%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+ + L+ A+ N G+TPLH I + LL+ GA + AV G P+ +A
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAA 441
Query: 71 SDAMADLLQKVI------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DLKTGGT 123
+++ +++ + V E + + + ++ + + +V K T
Sbjct: 442 FMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH++A G D+ + LL+ A P+ G+TPLH +A G ++ AA LL GA +
Sbjct: 502 PLHISARLGKADIVQQLLQQ-GASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSI 560
Query: 184 KNYSGQTCL 192
G T L
Sbjct: 561 TTKKGFTPL 569
Score = 55.6 bits (128), Expect = 5e-07
Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 12/185 (6%)
Query: 18 HGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADL 77
+ ADV G+TPLH A G I++A LL A V + P+ +A A++
Sbjct: 226 NNADVE--SKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 78 LQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD-LKTGGTPLHVAA 129
++ ++D +G + + L AR E L + K G +PLH+A
Sbjct: 284 VKLLLD-RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+++ + LL+ N D V + T LH AA G + A +LL A+P+ K +G
Sbjct: 343 QGDHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Query: 190 TCLDL 194
T L +
Sbjct: 402 TPLHI 406
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/177 (24%), Positives = 82/177 (46%), Gaps = 4/177 (2%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++++V L+ A+V+ +G T LH + G + + L+ +GA+V A + +G P
Sbjct: 84 EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTP 143
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRN--AEVDTLMSDAREWALHGYVEVRDLKTGGT 123
+ +A + ++++ ++D + + + + + + +E
Sbjct: 144 LYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRL 203
Query: 124 P-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
P LH+AA K A LL++ N + D G+TPLH AA +G A LLL A
Sbjct: 204 PALHIAARKDDTKAAALLLQNDN-NADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 14/187 (7%)
Query: 16 VTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
+ +G D+N + G LH + G + + LL+ A+V A G + IA A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL--------HGYVEVRDLKTGGTPLHV 127
+++ KV+ G + L A+E L +G + + G TPL V
Sbjct: 121 EVV-KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAV 179
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
A +G+ V LLE+ D LH AA +AAALLL+ + +++ S
Sbjct: 180 ALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKS 234
Query: 188 GQTCLDL 194
G T L +
Sbjct: 235 GFTPLHI 241
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 758
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 759 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 808
>AL121889-2|CAM27345.1| 467|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 467
Score = 93.1 bits (221), Expect = 2e-18
Identities = 40/94 (42%), Positives = 63/94 (67%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 51 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 110
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEV 97
+P D+ E + D+++ + +G+ EK V
Sbjct: 111 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRV 144
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH + ++ K LL A+ + D E WTPLHAAA G +L+++GAD
Sbjct: 43 GLTALHQCCIDNFEEIVKLLLSH-GANVNAKDNELWTPLHAAATCGHINLVKILVQYGAD 101
Query: 181 PHLKNYSGQTCLDLVD 196
N G DL +
Sbjct: 102 LLAVNSDGNMPYDLCE 117
>AL031657-2|CAM28212.1| 467|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 467
Score = 93.1 bits (221), Expect = 2e-18
Identities = 40/94 (42%), Positives = 63/94 (67%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 51 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 110
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEV 97
+P D+ E + D+++ + +G+ EK V
Sbjct: 111 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRV 144
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH + ++ K LL A+ + D E WTPLHAAA G +L+++GAD
Sbjct: 43 GLTALHQCCIDNFEEIVKLLLSH-GANVNAKDNELWTPLHAAATCGHINLVKILVQYGAD 101
Query: 181 PHLKNYSGQTCLDLVD 196
N G DL +
Sbjct: 102 LLAVNSDGNMPYDLCE 117
>AB177855-1|BAD66833.1| 467|Homo sapiens KIAA0823 splice variant 1
protein.
Length = 467
Score = 93.1 bits (221), Expect = 2e-18
Identities = 40/94 (42%), Positives = 63/94 (67%)
Query: 4 CIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
CID+ ++V+ L++HGA+VN DNE WTPLHA A+CG I++ + L++ GAD+ AVN DG
Sbjct: 51 CIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN 110
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEV 97
+P D+ E + D+++ + +G+ EK V
Sbjct: 111 MPYDLCEDEPTLDVIETCMAYQGITQEKINEMRV 144
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH + ++ K LL A+ + D E WTPLHAAA G +L+++GAD
Sbjct: 43 GLTALHQCCIDNFEEIVKLLLSH-GANVNAKDNELWTPLHAAATCGHINLVKILVQYGAD 101
Query: 181 PHLKNYSGQTCLDLVD 196
N G DL +
Sbjct: 102 LLAVNSDGNMPYDLCE 117
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 92.3 bits (219), Expect = 4e-18
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 9/195 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V+ LV+HGA+V D + +TPLHA AS G IS+ +YLL+ G D+ N G P+
Sbjct: 218 HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 277
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN-------AEVDTLMSDAREWALHGYVEVR-DLK 119
+A + ++ ++ID + +K+ A T + E + +V K
Sbjct: 278 VACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 337
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+ A G ++T+++ A DC D G TPLH AA +G + L+ GA
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 180 DPHLKNYSGQTCLDL 194
D + G L L
Sbjct: 397 DTAKRGIHGMFPLHL 411
Score = 74.5 bits (175), Expect = 9e-13
Identities = 74/251 (29%), Positives = 108/251 (43%), Gaps = 9/251 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ GA VN+ + +G+TPLH A AS L+ +GADV + D
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKD 338
Query: 62 GELPVDIAESDAMADLLQKVIDEKGV-DCE-KSRNAEVDTLMSDAREWALHGYV-EVRDL 118
G+ P+ + Q +I V DCE K+ N + E ++ + D
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA G+ D + LL D D D G T LHAAA G E LL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSS-GFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
L GAD + K+ G++ L + + A + + VN+ + P H D +
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 517
Query: 235 IKGQAEKIVND 245
K + ND
Sbjct: 518 GKCLEYLLRND 528
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 9/192 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
+ +V++L+ G D+N + G TPLH G + L++ GA V N G P+
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHF 311
Query: 69 AESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLM-------SDAREWALHGYVEVRDLKT 120
A + L +++ G D KS++ + M S ++ G V + K
Sbjct: 312 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 371
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+AA G+ + TL+ AD G PLH AAL G + LL G D
Sbjct: 372 GNTPLHIAARYGHELLINTLITS-GADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFD 430
Query: 181 PHLKNYSGQTCL 192
+ G+TCL
Sbjct: 431 IDTPDDFGRTCL 442
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+MV+ L++ GA++N D + +H A G I + + L+ GA+V + P+ A
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 246
Query: 70 ESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALH-----GYVEVRDLKTG 121
S M +++ ++D GVD + N + + ++ ++ G + + + G
Sbjct: 247 ASSGMISVVKYLLD-LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLH AAA + + LL AD + +G TPLH AL G+ + +++ GA
Sbjct: 306 FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 365
Query: 182 HLKNYSGQTCLDL 194
++ +G T L +
Sbjct: 366 DCEDKNGNTPLHI 378
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + D V L+ DVN DNE TPLHA A G I L+ SGA V A +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDS 105
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q ++ + +N + ++ A + L
Sbjct: 106 KWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN 165
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G+ ++ K LL A+ + D + +H AA G E
Sbjct: 166 VNVSD-RAGRTALHHAAFSGHGEMVKLLLSR-GANINAFDKKDRRAIHWAAYMGHIEVVK 223
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ T L
Sbjct: 224 LLVSHGAEVTCKDKKSYTPL 243
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
++ L+T GAD + G PLH A GF R LL SG D+ + G + A
Sbjct: 387 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 446
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGY-VEVRDL-KTGG 122
+ + L +++ G D K L A +AL G V DL + G
Sbjct: 447 AGGNLECLNLLLN-TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGC 505
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH AA L +A+P D +G+ +H +A +G + L+
Sbjct: 506 TPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLI 557
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D L++ G D++ D+ G T LHA A+ G + LL +GAD + G P+ A
Sbjct: 419 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYA 478
Query: 70 ESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVE--VRDL 118
++ L ++ DE+G C A E+ L +RD
Sbjct: 479 AANCNYQCLFALVGSGASVNDLDERG--CTPLHYAATSDTDGKCLEYLLRNDANPGIRD- 535
Query: 119 KTGGTPLHVAAAKGY-----IDVAKT----LLEDCNAD--PDCVDYEGWTPLHAAALWGQ 167
K G +H +AA G+ + ++T L+E D D + +PLH AA G
Sbjct: 536 KQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGH 595
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDL 194
+A +L++ D ++N SG+T LDL
Sbjct: 596 HQALEVLVQSLLDLDVRNSSGRTPLDL 622
Score = 49.2 bits (112), Expect = 4e-05
Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 17 THGADV-NRGDNEGW-TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
T G D+ + DN +PLH A G L++S D+ N G P+D+A
Sbjct: 569 TSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGH 628
Query: 75 ADLLQKVIDEKGVDCEKS---RNAEVDTLMSDAREWALH---GYVEVR---DLKTGG--T 123
+ + +I++ K + + ++ L G E + D++ G T
Sbjct: 629 VECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQT 688
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PL ++ G+ D +LL A+ D D G T LH A+ G +E LL+ GA L
Sbjct: 689 PLMLSVLNGHTDCVYSLLNK-GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLL 747
Query: 184 KNYSGQTCLDL 194
++ G+T + L
Sbjct: 748 RDSRGRTPIHL 758
Score = 48.8 bits (111), Expect = 5e-05
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A NL+ + L+ GAD N+ D G +PLH A A+C + + L+ SGA V ++
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA-LVGSGASVNDLDE 502
Query: 61 DGELPVD-IAESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSD--AREWA 108
G P+ A SD L+ ++ D++G + A L A E
Sbjct: 503 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETP 562
Query: 109 LHGYVEV--------RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLH 160
L +E D + +PLH+AA G+ + L++ D D + G TPL
Sbjct: 563 LDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGRTPLD 621
Query: 161 AAALWGQKEAAALLLKFGADPHLKNY 186
AA G E +L+ GA +K+Y
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDY 647
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ + L+ A + D + TPLH A +EA +LLK AD +
Sbjct: 76 TPLHAAAYLGDAEIIELLILS-GARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
++ + QT L + + + EA + VN + R
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Score = 41.1 bits (92), Expect = 0.011
Identities = 19/48 (39%), Positives = 29/48 (60%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA 57
+ V+ L+ HGA D+ G TP+H +A+CG I + LL+S A + A
Sbjct: 733 ECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 780
Score = 36.3 bits (80), Expect = 0.30
Identities = 27/80 (33%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + D E TPLHAAA G E LL+ GA + K+ T L S S +
Sbjct: 66 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 125
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
LK VN + P H
Sbjct: 126 LLKHSADVNARDKNWQTPLH 145
Score = 33.5 bits (73), Expect = 2.1
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 11/151 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNY- 60
A +++ V+ L+ GA + D TP+HA A+ G R L+ + AV+
Sbjct: 623 AAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQ 682
Query: 61 --DGELPVDIAESDAMADLLQKVIDE-KGVDCEKS--RNAEVDTLMSDAREW--AL--HG 111
+G+ P+ ++ + D + ++++ VD + R A ++ E AL HG
Sbjct: 683 DGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHG 742
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
+ G TP+H++AA G+I V LL+
Sbjct: 743 AKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 773
Score = 32.3 bits (70), Expect = 4.9
Identities = 20/69 (28%), Positives = 32/69 (46%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + ++ + D V L+ GA+V+ D G T LH A G LL+ GA +
Sbjct: 691 MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDS 750
Query: 61 DGELPVDIA 69
G P+ ++
Sbjct: 751 RGRTPIHLS 759
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 92.3 bits (219), Expect = 4e-18
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 9/195 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V+ LV+HGA+V D + +TPLHA AS G IS+ +YLL+ G D+ N G P+
Sbjct: 215 HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 274
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN-------AEVDTLMSDAREWALHGYVEVR-DLK 119
+A + ++ ++ID + +K+ A T + E + +V K
Sbjct: 275 VACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 334
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+ A G ++T+++ A DC D G TPLH AA +G + L+ GA
Sbjct: 335 DGKTPLHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 393
Query: 180 DPHLKNYSGQTCLDL 194
D + G L L
Sbjct: 394 DTAKRGIHGMFPLHL 408
Score = 74.5 bits (175), Expect = 9e-13
Identities = 74/251 (29%), Positives = 108/251 (43%), Gaps = 9/251 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ GA VN+ + +G+TPLH A AS L+ +GADV + D
Sbjct: 276 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKD 335
Query: 62 GELPVDIAESDAMADLLQKVIDEKGV-DCE-KSRNAEVDTLMSDAREWALHGYV-EVRDL 118
G+ P+ + Q +I V DCE K+ N + E ++ + D
Sbjct: 336 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 395
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA G+ D + LL D D D G T LHAAA G E LL
Sbjct: 396 AKRGIHGMFPLHLAALSGFSDCCRKLLSS-GFDIDTPDDFGRTCLHAAAAGGNLECLNLL 454
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
L GAD + K+ G++ L + + A + + VN+ + P H D +
Sbjct: 455 LNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 514
Query: 235 IKGQAEKIVND 245
K + ND
Sbjct: 515 GKCLEYLLRND 525
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 9/192 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
+ +V++L+ G D+N + G TPLH G + L++ GA V N G P+
Sbjct: 249 ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHF 308
Query: 69 AESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLM-------SDAREWALHGYVEVRDLKT 120
A + L +++ G D KS++ + M S ++ G V + K
Sbjct: 309 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 368
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+AA G+ + TL+ AD G PLH AAL G + LL G D
Sbjct: 369 GNTPLHIAARYGHELLINTLITS-GADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFD 427
Query: 181 PHLKNYSGQTCL 192
+ G+TCL
Sbjct: 428 IDTPDDFGRTCL 439
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+MV+ L++ GA++N D + +H A G I + + L+ GA+V + P+ A
Sbjct: 184 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 243
Query: 70 ESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALH-----GYVEVRDLKTG 121
S M +++ ++D GVD + N + + ++ ++ G + + + G
Sbjct: 244 ASSGMISVVKYLLD-LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKG 302
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLH AAA + + LL AD + +G TPLH AL G+ + +++ GA
Sbjct: 303 FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 362
Query: 182 HLKNYSGQTCLDL 194
++ +G T L +
Sbjct: 363 DCEDKNGNTPLHI 375
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + D V L+ DVN DNE TPLHA A G I L+ SGA V A +
Sbjct: 43 VQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDS 102
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q ++ + +N + ++ A + L
Sbjct: 103 KWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN 162
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G+ ++ K LL A+ + D + +H AA G E
Sbjct: 163 VNVSD-RAGRTALHHAAFSGHGEMVKLLLSR-GANINAFDKKDRRAIHWAAYMGHIEVVK 220
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ T L
Sbjct: 221 LLVSHGAEVTCKDKKSYTPL 240
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
++ L+T GAD + G PLH A GF R LL SG D+ + G + A
Sbjct: 384 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 443
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGY-VEVRDL-KTGG 122
+ + L +++ G D K L A +AL G V DL + G
Sbjct: 444 AGGNLECLNLLLN-TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGC 502
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH AA L +A+P D +G+ +H +A +G + L+
Sbjct: 503 TPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLI 554
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D L++ G D++ D+ G T LHA A+ G + LL +GAD + G P+ A
Sbjct: 416 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYA 475
Query: 70 ESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVE--VRDL 118
++ L ++ DE+G C A E+ L +RD
Sbjct: 476 AANCNYQCLFALVGSGASVNDLDERG--CTPLHYAATSDTDGKCLEYLLRNDANPGIRD- 532
Query: 119 KTGGTPLHVAAAKGY-----IDVAKT----LLEDCNAD--PDCVDYEGWTPLHAAALWGQ 167
K G +H +AA G+ + ++T L+E D D + +PLH AA G
Sbjct: 533 KQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGH 592
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDL 194
+A +L++ D ++N SG+T LDL
Sbjct: 593 HQALEVLVQSLLDLDVRNSSGRTPLDL 619
Score = 49.2 bits (112), Expect = 4e-05
Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 17 THGADV-NRGDNEGW-TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
T G D+ + DN +PLH A G L++S D+ N G P+D+A
Sbjct: 566 TSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGH 625
Query: 75 ADLLQKVIDEKGVDCEKS---RNAEVDTLMSDAREWALH---GYVEVR---DLKTGG--T 123
+ + +I++ K + + ++ L G E + D++ G T
Sbjct: 626 VECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQT 685
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PL ++ G+ D +LL A+ D D G T LH A+ G +E LL+ GA L
Sbjct: 686 PLMLSVLNGHTDCVYSLLNK-GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLL 744
Query: 184 KNYSGQTCLDL 194
++ G+T + L
Sbjct: 745 RDSRGRTPIHL 755
Score = 48.8 bits (111), Expect = 5e-05
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A NL+ + L+ GAD N+ D G +PLH A A+C + + L+ SGA V ++
Sbjct: 441 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA-LVGSGASVNDLDE 499
Query: 61 DGELPVD-IAESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSD--AREWA 108
G P+ A SD L+ ++ D++G + A L A E
Sbjct: 500 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETP 559
Query: 109 LHGYVEV--------RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLH 160
L +E D + +PLH+AA G+ + L++ D D + G TPL
Sbjct: 560 LDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGRTPLD 618
Query: 161 AAALWGQKEAAALLLKFGADPHLKNY 186
AA G E +L+ GA +K+Y
Sbjct: 619 LAAFKGHVECVDVLINQGASILVKDY 644
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ + L+ A + D + TPLH A +EA +LLK AD +
Sbjct: 73 TPLHAAAYLGDAEIIELLILS-GARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 131
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
++ + QT L + + + EA + VN + R
Sbjct: 132 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 168
Score = 41.1 bits (92), Expect = 0.011
Identities = 19/48 (39%), Positives = 29/48 (60%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA 57
+ V+ L+ HGA D+ G TP+H +A+CG I + LL+S A + A
Sbjct: 730 ECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 777
Score = 36.3 bits (80), Expect = 0.30
Identities = 27/80 (33%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + D E TPLHAAA G E LL+ GA + K+ T L S S +
Sbjct: 63 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 122
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
LK VN + P H
Sbjct: 123 LLKHSADVNARDKNWQTPLH 142
Score = 33.5 bits (73), Expect = 2.1
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 11/151 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNY- 60
A +++ V+ L+ GA + D TP+HA A+ G R L+ + AV+
Sbjct: 620 AAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQ 679
Query: 61 --DGELPVDIAESDAMADLLQKVIDE-KGVDCEKS--RNAEVDTLMSDAREW--AL--HG 111
+G+ P+ ++ + D + ++++ VD + R A ++ E AL HG
Sbjct: 680 DGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHG 739
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
+ G TP+H++AA G+I V LL+
Sbjct: 740 AKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 770
Score = 32.3 bits (70), Expect = 4.9
Identities = 20/69 (28%), Positives = 32/69 (46%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + ++ + D V L+ GA+V+ D G T LH A G LL+ GA +
Sbjct: 688 MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDS 747
Query: 61 DGELPVDIA 69
G P+ ++
Sbjct: 748 RGRTPIHLS 756
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 92.3 bits (219), Expect = 4e-18
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 9/195 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V+ LV+HGA+V D + +TPLHA AS G IS+ +YLL+ G D+ N G P+
Sbjct: 218 HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 277
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN-------AEVDTLMSDAREWALHGYVEVR-DLK 119
+A + ++ ++ID + +K+ A T + E + +V K
Sbjct: 278 VACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 337
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+ A G ++T+++ A DC D G TPLH AA +G + L+ GA
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 180 DPHLKNYSGQTCLDL 194
D + G L L
Sbjct: 397 DTAKRGIHGMFPLHL 411
Score = 74.5 bits (175), Expect = 9e-13
Identities = 74/251 (29%), Positives = 108/251 (43%), Gaps = 9/251 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ GA VN+ + +G+TPLH A AS L+ +GADV + D
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKD 338
Query: 62 GELPVDIAESDAMADLLQKVIDEKGV-DCE-KSRNAEVDTLMSDAREWALHGYV-EVRDL 118
G+ P+ + Q +I V DCE K+ N + E ++ + D
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA G+ D + LL D D D G T LHAAA G E LL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSS-GFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
L GAD + K+ G++ L + + A + + VN+ + P H D +
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 517
Query: 235 IKGQAEKIVND 245
K + ND
Sbjct: 518 GKCLEYLLRND 528
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 9/192 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
+ +V++L+ G D+N + G TPLH G + L++ GA V N G P+
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHF 311
Query: 69 AESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLM-------SDAREWALHGYVEVRDLKT 120
A + L +++ G D KS++ + M S ++ G V + K
Sbjct: 312 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 371
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+AA G+ + TL+ AD G PLH AAL G + LL G D
Sbjct: 372 GNTPLHIAARYGHELLINTLITS-GADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFD 430
Query: 181 PHLKNYSGQTCL 192
+ G+TCL
Sbjct: 431 IDTPDDFGRTCL 442
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+MV+ L++ GA++N D + +H A G I + + L+ GA+V + P+ A
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 246
Query: 70 ESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALH-----GYVEVRDLKTG 121
S M +++ ++D GVD + N + + ++ ++ G + + + G
Sbjct: 247 ASSGMISVVKYLLD-LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLH AAA + + LL AD + +G TPLH AL G+ + +++ GA
Sbjct: 306 FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 365
Query: 182 HLKNYSGQTCLDL 194
++ +G T L +
Sbjct: 366 DCEDKNGNTPLHI 378
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + D V L+ DVN DNE TPLHA A G I L+ SGA V A +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDS 105
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q ++ + +N + ++ A + L
Sbjct: 106 KWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN 165
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G+ ++ K LL A+ + D + +H AA G E
Sbjct: 166 VNVSD-RAGRTALHHAAFSGHGEMVKLLLSR-GANINAFDKKDRRAIHWAAYMGHIEVVK 223
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ T L
Sbjct: 224 LLVSHGAEVTCKDKKSYTPL 243
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
++ L+T GAD + G PLH A GF R LL SG D+ + G + A
Sbjct: 387 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 446
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGY-VEVRDL-KTGG 122
+ + L +++ G D K L A +AL G V DL + G
Sbjct: 447 AGGNLECLNLLLN-TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGC 505
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH AA L +A+P D +G+ +H +A +G + L+
Sbjct: 506 TPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLI 557
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D L++ G D++ D+ G T LHA A+ G + LL +GAD + G P+ A
Sbjct: 419 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYA 478
Query: 70 ESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVE--VRDL 118
++ L ++ DE+G C A E+ L +RD
Sbjct: 479 AANCNYQCLFALVGSGASVNDLDERG--CTPLHYAATSDTDGKCLEYLLRNDANPGIRD- 535
Query: 119 KTGGTPLHVAAAKGY-----IDVAKT----LLEDCNAD--PDCVDYEGWTPLHAAALWGQ 167
K G +H +AA G+ + ++T L+E D D + +PLH AA G
Sbjct: 536 KQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGH 595
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDL 194
+A +L++ D ++N SG+T LDL
Sbjct: 596 HQALEVLVQSLLDLDVRNSSGRTPLDL 622
Score = 49.2 bits (112), Expect = 4e-05
Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 17 THGADV-NRGDNEGW-TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
T G D+ + DN +PLH A G L++S D+ N G P+D+A
Sbjct: 569 TSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGH 628
Query: 75 ADLLQKVIDEKGVDCEKS---RNAEVDTLMSDAREWALH---GYVEVR---DLKTGG--T 123
+ + +I++ K + + ++ L G E + D++ G T
Sbjct: 629 VECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQT 688
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PL ++ G+ D +LL A+ D D G T LH A+ G +E LL+ GA L
Sbjct: 689 PLMLSVLNGHTDCVYSLLNK-GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLL 747
Query: 184 KNYSGQTCLDL 194
++ G+T + L
Sbjct: 748 RDSRGRTPIHL 758
Score = 48.8 bits (111), Expect = 5e-05
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A NL+ + L+ GAD N+ D G +PLH A A+C + + L+ SGA V ++
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA-LVGSGASVNDLDE 502
Query: 61 DGELPVD-IAESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSD--AREWA 108
G P+ A SD L+ ++ D++G + A L A E
Sbjct: 503 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETP 562
Query: 109 LHGYVEV--------RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLH 160
L +E D + +PLH+AA G+ + L++ D D + G TPL
Sbjct: 563 LDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGRTPLD 621
Query: 161 AAALWGQKEAAALLLKFGADPHLKNY 186
AA G E +L+ GA +K+Y
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDY 647
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ + L+ A + D + TPLH A +EA +LLK AD +
Sbjct: 76 TPLHAAAYLGDAEIIELLILS-GARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
++ + QT L + + + EA + VN + R
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Score = 41.1 bits (92), Expect = 0.011
Identities = 19/48 (39%), Positives = 29/48 (60%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA 57
+ V+ L+ HGA D+ G TP+H +A+CG I + LL+S A + A
Sbjct: 733 ECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDA 780
Score = 36.3 bits (80), Expect = 0.30
Identities = 27/80 (33%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + D E TPLHAAA G E LL+ GA + K+ T L S S +
Sbjct: 66 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 125
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
LK VN + P H
Sbjct: 126 LLKHSADVNARDKNWQTPLH 145
Score = 33.5 bits (73), Expect = 2.1
Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 11/151 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNY- 60
A +++ V+ L+ GA + D TP+HA A+ G R L+ + AV+
Sbjct: 623 AAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQ 682
Query: 61 --DGELPVDIAESDAMADLLQKVIDE-KGVDCEKS--RNAEVDTLMSDAREW--AL--HG 111
+G+ P+ ++ + D + ++++ VD + R A ++ E AL HG
Sbjct: 683 DGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHG 742
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
+ G TP+H++AA G+I V LL+
Sbjct: 743 AKCLLRDSRGRTPIHLSAACGHIGVLGALLQ 773
Score = 32.3 bits (70), Expect = 4.9
Identities = 20/69 (28%), Positives = 32/69 (46%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + ++ + D V L+ GA+V+ D G T LH A G LL+ GA +
Sbjct: 691 MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDS 750
Query: 61 DGELPVDIA 69
G P+ ++
Sbjct: 751 RGRTPIHLS 759
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 92.3 bits (219), Expect = 4e-18
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 9/195 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V+ LV+HGA+V D + +TPLHA AS G IS+ +YLL+ G D+ N G P+
Sbjct: 218 HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 277
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN-------AEVDTLMSDAREWALHGYVEVR-DLK 119
+A + ++ ++ID + +K+ A T + E + +V K
Sbjct: 278 VACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 337
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+ A G ++T+++ A DC D G TPLH AA +G + L+ GA
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 180 DPHLKNYSGQTCLDL 194
D + G L L
Sbjct: 397 DTAKRGIHGMFPLHL 411
Score = 74.5 bits (175), Expect = 9e-13
Identities = 74/251 (29%), Positives = 108/251 (43%), Gaps = 9/251 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ GA VN+ + +G+TPLH A AS L+ +GADV + D
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKD 338
Query: 62 GELPVDIAESDAMADLLQKVIDEKGV-DCE-KSRNAEVDTLMSDAREWALHGYV-EVRDL 118
G+ P+ + Q +I V DCE K+ N + E ++ + D
Sbjct: 339 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 398
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA G+ D + LL D D D G T LHAAA G E LL
Sbjct: 399 AKRGIHGMFPLHLAALSGFSDCCRKLLSS-GFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
L GAD + K+ G++ L + + A + + VN+ + P H D +
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 517
Query: 235 IKGQAEKIVND 245
K + ND
Sbjct: 518 GKCLEYLLRND 528
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 9/192 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
+ +V++L+ G D+N + G TPLH G + L++ GA V N G P+
Sbjct: 252 ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHF 311
Query: 69 AESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLM-------SDAREWALHGYVEVRDLKT 120
A + L +++ G D KS++ + M S ++ G V + K
Sbjct: 312 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 371
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+AA G+ + TL+ AD G PLH AAL G + LL G D
Sbjct: 372 GNTPLHIAARYGHELLINTLITS-GADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFD 430
Query: 181 PHLKNYSGQTCL 192
+ G+TCL
Sbjct: 431 IDTPDDFGRTCL 442
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+MV+ L++ GA++N D + +H A G I + + L+ GA+V + P+ A
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 246
Query: 70 ESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALH-----GYVEVRDLKTG 121
S M +++ ++D GVD + N + + ++ ++ G + + + G
Sbjct: 247 ASSGMISVVKYLLD-LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLH AAA + + LL AD + +G TPLH AL G+ + +++ GA
Sbjct: 306 FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 365
Query: 182 HLKNYSGQTCLDL 194
++ +G T L +
Sbjct: 366 DCEDKNGNTPLHI 378
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + D V L+ DVN DNE TPLHA A G I L+ SGA V A +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDS 105
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q ++ + +N + ++ A + L
Sbjct: 106 KWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN 165
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G+ ++ K LL A+ + D + +H AA G E
Sbjct: 166 VNVSD-RAGRTALHHAAFSGHGEMVKLLLSR-GANINAFDKKDRRAIHWAAYMGHIEVVK 223
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ T L
Sbjct: 224 LLVSHGAEVTCKDKKSYTPL 243
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
++ L+T GAD + G PLH A GF R LL SG D+ + G + A
Sbjct: 387 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 446
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGY-VEVRDL-KTGG 122
+ + L +++ G D K L A +AL G V DL + G
Sbjct: 447 AGGNLECLNLLLN-TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGC 505
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH AA L +A+P D +G+ +H +A +G + L+
Sbjct: 506 TPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLI 557
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/207 (28%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D L++ G D++ D+ G T LHA A+ G + LL +GAD + G P+ A
Sbjct: 419 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYA 478
Query: 70 ESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVE--VRDL 118
++ L ++ DE+G C A E+ L VRD
Sbjct: 479 AANCNYQCLFALVGSGASVNDLDERG--CTPLHYAATSDTDGKCLEYLLRNDANPGVRD- 535
Query: 119 KTGGTPLHVAAAKGY-----IDVAKT----LLEDCNAD--PDCVDYEGWTPLHAAALWGQ 167
K G +H +AA G+ + ++T L+E D D + +PLH AA G
Sbjct: 536 KQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGH 595
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDL 194
+A +L++ D ++N SG+T LDL
Sbjct: 596 HQALEVLVQSLLDLDVRNSSGRTPLDL 622
Score = 48.8 bits (111), Expect = 5e-05
Identities = 59/206 (28%), Positives = 91/206 (44%), Gaps = 23/206 (11%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A NL+ + L+ GAD N+ D G +PLH A A+C + + L+ SGA V ++
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA-LVGSGASVNDLDE 502
Query: 61 DGELPVD-IAESDAMADLLQKVI---DEKGVDCEKSRNAEVDT--------LMSDAREWA 108
G P+ A SD L+ ++ GV ++ NA + L A E
Sbjct: 503 RGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETP 562
Query: 109 LHGYVEV--------RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLH 160
L +E D + +PLH+AA G+ + L++ D D + G TPL
Sbjct: 563 LDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGRTPLD 621
Query: 161 AAALWGQKEAAALLLKFGADPHLKNY 186
AA G E +L+ GA +K+Y
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDY 647
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ + L+ A + D + TPLH A +EA +LLK AD +
Sbjct: 76 TPLHAAAYLGDAEIIELLILS-GARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
++ + QT L + + + EA + VN + R
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 171
Score = 40.7 bits (91), Expect = 0.014
Identities = 56/194 (28%), Positives = 77/194 (39%), Gaps = 22/194 (11%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFIS-IARYLLESGADVAAVNYD 61
A + N + LV GA VN D G TPLH A+ YLL + A+ +
Sbjct: 478 AAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQ 537
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-------ALHGY-- 112
G V + + LQ + E +D + SD R A HG+
Sbjct: 538 GYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQ 597
Query: 113 ---VEVRDL-------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDY-EGWTPLHA 161
V V+ L +G TPL +AA KG+++ L+ A DY TP+HA
Sbjct: 598 ALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQ-GASILVKDYILKRTPIHA 656
Query: 162 AALWGQKEAAALLL 175
AA G E LL+
Sbjct: 657 AATNGHSECLRLLI 670
Score = 36.3 bits (80), Expect = 0.30
Identities = 27/80 (33%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + D E TPLHAAA G E LL+ GA + K+ T L S S +
Sbjct: 66 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 125
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
LK VN + P H
Sbjct: 126 LLKHSADVNARDKNWQTPLH 145
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 92.3 bits (219), Expect = 4e-18
Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 9/195 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++V+ LV+HGA+V D + +TPLHA AS G IS+ +YLL+ G D+ N G P+
Sbjct: 191 HIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 250
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN-------AEVDTLMSDAREWALHGYVEVR-DLK 119
+A + ++ ++ID + +K+ A T + E + +V K
Sbjct: 251 VACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSK 310
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+ A G ++T+++ A DC D G TPLH AA +G + L+ GA
Sbjct: 311 DGKTPLHMTALHGRFSRSQTIIQS-GAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 369
Query: 180 DPHLKNYSGQTCLDL 194
D + G L L
Sbjct: 370 DTAKRGIHGMFPLHL 384
Score = 74.5 bits (175), Expect = 9e-13
Identities = 74/251 (29%), Positives = 108/251 (43%), Gaps = 9/251 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ GA VN+ + +G+TPLH A AS L+ +GADV + D
Sbjct: 252 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKD 311
Query: 62 GELPVDIAESDAMADLLQKVIDEKGV-DCE-KSRNAEVDTLMSDAREWALHGYV-EVRDL 118
G+ P+ + Q +I V DCE K+ N + E ++ + D
Sbjct: 312 GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADT 371
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA G+ D + LL D D D G T LHAAA G E LL
Sbjct: 372 AKRGIHGMFPLHLAALSGFSDCCRKLLSS-GFDIDTPDDFGRTCLHAAAAGGNLECLNLL 430
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
L GAD + K+ G++ L + + A + + VN+ + P H D +
Sbjct: 431 LNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 490
Query: 235 IKGQAEKIVND 245
K + ND
Sbjct: 491 GKCLEYLLRND 501
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 9/192 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
+ +V++L+ G D+N + G TPLH G + L++ GA V N G P+
Sbjct: 225 ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHF 284
Query: 69 AESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLM-------SDAREWALHGYVEVRDLKT 120
A + L +++ G D KS++ + M S ++ G V + K
Sbjct: 285 AAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN 344
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+AA G+ + TL+ AD G PLH AAL G + LL G D
Sbjct: 345 GNTPLHIAARYGHELLINTLITS-GADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFD 403
Query: 181 PHLKNYSGQTCL 192
+ G+TCL
Sbjct: 404 IDTPDDFGRTCL 415
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+MV+ L++ GA++N D + +H A G I + + L+ GA+V + P+ A
Sbjct: 160 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAA 219
Query: 70 ESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALH-----GYVEVRDLKTG 121
S M +++ ++D GVD + N + + ++ ++ G + + + G
Sbjct: 220 ASSGMISVVKYLLD-LGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKG 278
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLH AAA + + LL AD + +G TPLH AL G+ + +++ GA
Sbjct: 279 FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 338
Query: 182 HLKNYSGQTCLDL 194
++ +G T L +
Sbjct: 339 DCEDKNGNTPLHI 351
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + D V L+ DVN DNE TPLHA A G I L+ SGA V A +
Sbjct: 19 VQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDS 78
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q ++ + +N + ++ A + L
Sbjct: 79 KWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSN 138
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G+ ++ K LL A+ + D + +H AA G E
Sbjct: 139 VNVSD-RAGRTALHHAAFSGHGEMVKLLLSR-GANINAFDKKDRRAIHWAAYMGHIEVVK 196
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ T L
Sbjct: 197 LLVSHGAEVTCKDKKSYTPL 216
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/174 (30%), Positives = 79/174 (45%), Gaps = 14/174 (8%)
Query: 3 ACIDDNLDMVEFLV-THGAD-VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
A I+DN E L+ T GA VN D++G TPLHA A + + LL A V +V+
Sbjct: 801 AVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS 860
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDC---EKSRNAEVDTLMSDAREWALHGYVEV-- 115
G+ P+ +A + + ++ ++ + + S+N + S E + +E
Sbjct: 861 TGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKIT 920
Query: 116 -RDLKTG-----GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAA 163
R+L TPLHVAA G V + LL A VD G+TP A A
Sbjct: 921 DRNLINATNAALQTPLHVAARNGLTMVVQELLGK-GASVLAVDENGYTPALACA 973
Score = 52.0 bits (119), Expect = 6e-06
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + ++ + D V L+ GA+V+ D G T LH A G LL+ GA +
Sbjct: 664 MLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDS 723
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-GYVEVRDL- 118
G P+ ++ + +L ++ + + A D A WA + G+ +L
Sbjct: 724 RGRTPIHLSAACGHIGVLGALL--QSAASMDANPATADNHGYTALHWACYNGHETCVELL 781
Query: 119 -------KTGG---TPLHVAAAKGYIDVAKTLLEDCNAD-PDCVDYEGWTPLHAAALWGQ 167
KT G +PLH A A+ L++ A + D +G TPLHAAA
Sbjct: 782 LEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDH 841
Query: 168 KEAAALLLKFGADPHLKNYSGQTCL 192
E LLL A + + +G+T L
Sbjct: 842 VECLQLLLSHNAQVNSVDSTGKTPL 866
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/172 (27%), Positives = 71/172 (41%), Gaps = 9/172 (5%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
++ L+T GAD + G PLH A GF R LL SG D+ + G + A
Sbjct: 360 LINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAA 419
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGY-VEVRDL-KTGG 122
+ + L +++ G D K L A +AL G V DL + G
Sbjct: 420 AGGNLECLNLLLN-TGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGC 478
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH AA L +A+P D +G+ +H +A +G + L+
Sbjct: 479 TPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLI 530
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 25/207 (12%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D L++ G D++ D+ G T LHA A+ G + LL +GAD + G P+ A
Sbjct: 392 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYA 451
Query: 70 ESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSDAREWALHGYVE--VRDL 118
++ L ++ DE+G C A E+ L +RD
Sbjct: 452 AANCNYQCLFALVGSGASVNDLDERG--CTPLHYAATSDTDGKCLEYLLRNDANPGIRD- 508
Query: 119 KTGGTPLHVAAAKGY-----IDVAKT----LLEDCNAD--PDCVDYEGWTPLHAAALWGQ 167
K G +H +AA G+ + ++T L+E D D + +PLH AA G
Sbjct: 509 KQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGH 568
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDL 194
+A +L++ D ++N SG+T LDL
Sbjct: 569 HQALEVLVQSLLDLDVRNSSGRTPLDL 595
Score = 49.2 bits (112), Expect = 4e-05
Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 17 THGADV-NRGDNEGW-TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
T G D+ + DN +PLH A G L++S D+ N G P+D+A
Sbjct: 542 TSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGH 601
Query: 75 ADLLQKVIDEKGVDCEKS---RNAEVDTLMSDAREWALH---GYVEVR---DLKTGG--T 123
+ + +I++ K + + ++ L G E + D++ G T
Sbjct: 602 VECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQT 661
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PL ++ G+ D +LL A+ D D G T LH A+ G +E LL+ GA L
Sbjct: 662 PLMLSVLNGHTDCVYSLLNK-GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLL 720
Query: 184 KNYSGQTCLDL 194
++ G+T + L
Sbjct: 721 RDSRGRTPIHL 731
Score = 48.8 bits (111), Expect = 5e-05
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A NL+ + L+ GAD N+ D G +PLH A A+C + + L+ SGA V ++
Sbjct: 417 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA-LVGSGASVNDLDE 475
Query: 61 DGELPVD-IAESDAMADLLQKVI---------DEKGVDCEKSRNAEVDTLMSD--AREWA 108
G P+ A SD L+ ++ D++G + A L A E
Sbjct: 476 RGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETP 535
Query: 109 LHGYVEV--------RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLH 160
L +E D + +PLH+AA G+ + L++ D D + G TPL
Sbjct: 536 LDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL-LDLDVRNSSGRTPLD 594
Query: 161 AAALWGQKEAAALLLKFGADPHLKNY 186
AA G E +L+ GA +K+Y
Sbjct: 595 LAAFKGHVECVDVLINQGASILVKDY 620
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ + L+ A + D + TPLH A +EA +LLK AD +
Sbjct: 49 TPLHAAAYLGDAEIIELLILS-GARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 107
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
++ + QT L + + + EA + VN + R
Sbjct: 108 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDR 144
Score = 37.5 bits (83), Expect = 0.13
Identities = 42/169 (24%), Positives = 70/169 (41%), Gaps = 10/169 (5%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA---ESDAMADLLQKVI 82
DN G+T LH G + LLE + P+ A +++ A++L +
Sbjct: 759 DNHGYTALHWACYNGHETCVELLLEQEV-FQKTEGNAFSPLHCAVINDNEGAAEMLIDTL 817
Query: 83 DEKGVDCEKSR-----NAEVDTLMSDAREWALHGYVEVRDL-KTGGTPLHVAAAKGYIDV 136
V+ S+ +A T + + L +V + TG TPL +AA G +
Sbjct: 818 GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT 877
Query: 137 AKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
+ L+ +A+ D T LH A G + +A L+L+ D +L N
Sbjct: 878 VEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLIN 926
Score = 36.3 bits (80), Expect = 0.30
Identities = 27/80 (33%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + D E TPLHAAA G E LL+ GA + K+ T L S S +
Sbjct: 39 DVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV 98
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
LK VN + P H
Sbjct: 99 LLKHSADVNARDKNWQTPLH 118
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA 53
+A D+++ ++ L++H A VN D+ G TPL A G + L+ S +
Sbjct: 835 AAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSAS 886
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 91.9 bits (218), Expect = 6e-18
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+V L+ HGA+V D +G+TPLHA AS G I++ ++LL G ++ +N G +
Sbjct: 185 HLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALH 244
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN--------AEVDTLMSDAREWALHGYVEVR-DL 118
IA + ++ ++ID G + + N A T + E ++ +V
Sbjct: 245 IACYNGQDAVVNELID-YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQS 303
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G +PLH+ A G ++TL+++ + DCVD +G TPLH AA +G + L+ G
Sbjct: 304 KDGKSPLHMTAVHGRFTRSQTLIQN-GGEIDCVDKDGNTPLHVAARYGHELLINTLITSG 362
Query: 179 AD 180
AD
Sbjct: 363 AD 364
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 18/197 (9%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++E L+ GA VN DN TPLH + + L++ ADV A + + + P+ +A
Sbjct: 55 EIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVA 114
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL----------- 118
++ + +I R T + A AL+G+VE+ +L
Sbjct: 115 AANKAVKCAEVIIPLLSSVNVSDRGGR--TALHHA---ALNGHVEMVNLLLAKGANINAF 169
Query: 119 -KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K LH AA G++DV LL + A+ C D +G+TPLHAAA GQ LL
Sbjct: 170 DKKDRRALHWAAYMGHLDVV-ALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNL 228
Query: 178 GADPHLKNYSGQTCLDL 194
G + N G T L +
Sbjct: 229 GVEIDEINVYGNTALHI 245
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/198 (23%), Positives = 94/198 (47%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ +++MV L+ GA++N D + LH A G + + L+ GA+V + G
Sbjct: 147 AALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG 206
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALHGYVEV---- 115
P+ A S+ ++++ +++ GV+ ++ N + + ++ ++ ++
Sbjct: 207 YTPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANV 265
Query: 116 -RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ G TPLH AAA + + LL + AD + +G +PLH A+ G+ + L
Sbjct: 266 NQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTL 325
Query: 175 LKFGADPHLKNYSGQTCL 192
++ G + + G T L
Sbjct: 326 IQNGGEIDCVDKDGNTPL 343
Score = 58.4 bits (135), Expect = 7e-08
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + + L+ DVN D+E TPLH A G I L+ SGA V A +
Sbjct: 13 VQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDN 72
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q +I + +N + ++ A + L
Sbjct: 73 MWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSS 132
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G++++ LL A+ + D + LH AA G + A
Sbjct: 133 VNVSD-RGGRTALHHAALNGHVEMVNLLLAK-GANINAFDKKDRRALHWAAYMGHLDVVA 190
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ G T L
Sbjct: 191 LLINHGAEVTCKDKKGYTPL 210
Score = 35.1 bits (77), Expect = 0.70
Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 1/107 (0%)
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T PL A G + + L+ D + +D E TPLH AA G E LL+ GA
Sbjct: 7 TDQPPLVQAIFSGDPEEIRMLIHKTE-DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
+ K+ T L S S + +K VN + P H
Sbjct: 66 RVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLH 112
Score = 34.7 bits (76), Expect = 0.93
Identities = 16/42 (38%), Positives = 24/42 (57%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVA 56
L+ +G +++ D +G TPLH A G + L+ SGAD A
Sbjct: 325 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTA 366
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 91.9 bits (218), Expect = 6e-18
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+V L+ HGA+V D +G+TPLHA AS G I++ ++LL G ++ +N G +
Sbjct: 124 HLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALH 183
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN--------AEVDTLMSDAREWALHGYVEVR-DL 118
IA + ++ ++ID G + + N A T + E ++ +V
Sbjct: 184 IACYNGQDAVVNELID-YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQS 242
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G +PLH+ A G ++TL+++ + DCVD +G TPLH AA +G + L+ G
Sbjct: 243 KDGKSPLHMTAVHGRFTRSQTLIQN-GGEIDCVDKDGNTPLHVAARYGHELLINTLITSG 301
Query: 179 AD 180
AD
Sbjct: 302 AD 303
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/198 (23%), Positives = 94/198 (47%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ +++MV L+ GA++N D + LH A G + + L+ GA+V + G
Sbjct: 86 AALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG 145
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALHGYVEV---- 115
P+ A S+ ++++ +++ GV+ ++ N + + ++ ++ ++
Sbjct: 146 YTPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANV 204
Query: 116 -RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ G TPLH AAA + + LL + AD + +G +PLH A+ G+ + L
Sbjct: 205 NQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTL 264
Query: 175 LKFGADPHLKNYSGQTCL 192
++ G + + G T L
Sbjct: 265 IQNGGEIDCVDKDGNTPL 282
Score = 62.5 bits (145), Expect = 4e-09
Identities = 56/190 (29%), Positives = 81/190 (42%), Gaps = 8/190 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+ V+ L+ H ADVN D TPLH A+ + A ++ + V + G + A
Sbjct: 27 EAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHA 86
Query: 70 ESDAMAD----LLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKTGG 122
+ + LL K + D + R M AL HG K G
Sbjct: 87 ALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGY 146
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA+ G I+V K LL + + D ++ G T LH A GQ L+ +GA+ +
Sbjct: 147 TPLHAAASNGQINVVKHLL-NLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVN 205
Query: 183 LKNYSGQTCL 192
N +G T L
Sbjct: 206 QPNNNGFTPL 215
Score = 61.7 bits (143), Expect = 7e-09
Identities = 56/188 (29%), Positives = 82/188 (43%), Gaps = 18/188 (9%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
GA VN DN TPLH + + L++ ADV A + + + P+ +A ++
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCA 62
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL------------KTGGTPLH 126
+ +I R T + A AL+G+VE+ +L K LH
Sbjct: 63 EVIIPLLSSVNVSDRGGR--TALHHA---ALNGHVEMVNLLLAKGANINAFDKKDRRALH 117
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
AA G++DV L+ A+ C D +G+TPLHAAA GQ LL G + N
Sbjct: 118 WAAYMGHLDVVALLINH-GAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINV 176
Query: 187 SGQTCLDL 194
G T L +
Sbjct: 177 YGNTALHI 184
Score = 34.7 bits (76), Expect = 0.93
Identities = 16/42 (38%), Positives = 24/42 (57%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVA 56
L+ +G +++ D +G TPLH A G + L+ SGAD A
Sbjct: 264 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTA 305
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 91.9 bits (218), Expect = 6e-18
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+V L+ HGA+V D +G+TPLHA AS G I++ ++LL G ++ +N G +
Sbjct: 185 HLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALH 244
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN--------AEVDTLMSDAREWALHGYVEVR-DL 118
IA + ++ ++ID G + + N A T + E ++ +V
Sbjct: 245 IACYNGQDAVVNELID-YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQS 303
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G +PLH+ A G ++TL+++ + DCVD +G TPLH AA +G + L+ G
Sbjct: 304 KDGKSPLHMTAVHGRFTRSQTLIQN-GGEIDCVDKDGNTPLHVAARYGHELLINTLITSG 362
Query: 179 AD 180
AD
Sbjct: 363 AD 364
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ +GA+VN+ +N G+TPLH A AS L+ +GADV + D
Sbjct: 246 ACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKD 305
Query: 62 GELPVDIAESDAMADLLQKVIDEKG-VDC-EKSRNAEVDTLMSDAREWALHGYVEV-RDL 118
G+ P+ + Q +I G +DC +K N + E ++ + D
Sbjct: 306 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 365
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA + D + LL + D D G T LHAAA G E LL
Sbjct: 366 AKCGIHSMFPLHLAALNAHSDCCRKLLSS-GFEIDTPDKFGRTCLHAAAAGGNVECIKLL 424
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD H K+ G+T L
Sbjct: 425 QSSGADFHKKDKCGRTPL 442
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 18/197 (9%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++E L+ GA VN DN TPLH + + L++ ADV A + + + P+ +A
Sbjct: 55 EIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVA 114
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL----------- 118
++ + +I R T + A AL+G+VE+ +L
Sbjct: 115 AANKAVKCAEVIIPLLSSVNVSDRGGR--TALHHA---ALNGHVEMVNLLLAKGANINAF 169
Query: 119 -KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K LH AA G++DV LL + A+ C D +G+TPLHAAA GQ LL
Sbjct: 170 DKKDRRALHWAAYMGHLDVV-ALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNL 228
Query: 178 GADPHLKNYSGQTCLDL 194
G + N G T L +
Sbjct: 229 GVEIDEINVYGNTALHI 245
Score = 67.3 bits (157), Expect = 1e-10
Identities = 59/190 (31%), Positives = 90/190 (47%), Gaps = 12/190 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
+E LV +GADVN +G +PLH TA G + ++ L+++G ++ V+ DG P+ +A
Sbjct: 289 LELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAAR 348
Query: 72 DAMADLLQKVIDEKGVDCEKS--------RNAEVDTLMSDAREWALHGY-VEVRDLKTGG 122
+LL + G D K A ++ R+ G+ ++ D K G
Sbjct: 349 YGH-ELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPD-KFGR 406
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH AAA G ++ K LL+ AD D G TPLH AA L+ GA+ +
Sbjct: 407 TCLHAAAAGGNVECIK-LLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVN 465
Query: 183 LKNYSGQTCL 192
+ G+T L
Sbjct: 466 ETDDWGRTAL 475
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/198 (23%), Positives = 94/198 (47%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ +++MV L+ GA++N D + LH A G + + L+ GA+V + G
Sbjct: 147 AALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG 206
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALHGYVEV---- 115
P+ A S+ ++++ +++ GV+ ++ N + + ++ ++ ++
Sbjct: 207 YTPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANV 265
Query: 116 -RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ G TPLH AAA + + LL + AD + +G +PLH A+ G+ + L
Sbjct: 266 NQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTL 325
Query: 175 LKFGADPHLKNYSGQTCL 192
++ G + + G T L
Sbjct: 326 IQNGGEIDCVDKDGNTPL 343
Score = 58.4 bits (135), Expect = 7e-08
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A + + + L+ DVN D+E TPLH A G I L+ SGA V A +
Sbjct: 13 VQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDN 72
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGY 112
P+ A + + +Q +I + +N + ++ A + L
Sbjct: 73 MWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSS 132
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V D + G T LH AA G++++ LL A+ + D + LH AA G + A
Sbjct: 133 VNVSD-RGGRTALHHAALNGHVEMVNLLLAK-GANINAFDKKDRRALHWAAYMGHLDVVA 190
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL+ GA+ K+ G T L
Sbjct: 191 LLINHGAEVTCKDKKGYTPL 210
Score = 58.0 bits (134), Expect = 9e-08
Identities = 53/200 (26%), Positives = 89/200 (44%), Gaps = 11/200 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + +++V+ L+ G +++ + G T LH G ++ L++ GA+V N +
Sbjct: 212 AAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNN 271
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLMSD-----AREWAL---HGY 112
G P+ A + L +++ G D +S++ + M+ R L G
Sbjct: 272 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 331
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
++ D K G TPLHVAA G+ + TL+ AD PLH AAL +
Sbjct: 332 IDCVD-KDGNTPLHVAARYGHELLINTLITS-GADTAKCGIHSMFPLHLAALNAHSDCCR 389
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL G + + G+TCL
Sbjct: 390 KLLSSGFEIDTPDKFGRTCL 409
Score = 37.9 bits (84), Expect = 0.099
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 23/187 (12%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D L++ G +++ D G T LHA A+ G + + L SGAD + G
Sbjct: 379 AALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCG 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A ++ ++ ++ + A V+ D ALH Y D+
Sbjct: 439 RTPLHYAAANCHFHCIETLV---------TTGANVNE-TDDWGRTALH-YAAASDMDRNK 487
Query: 123 TPLHVAAAKG-YIDVAKTLLED----C-------NADPDCVDYEGWTPLHAAALWGQKEA 170
T L A ++ A+ L E C +A+P D EG+ +H AA +G ++
Sbjct: 488 TILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQC 547
Query: 171 AALLLKF 177
L+ F
Sbjct: 548 LELVSCF 554
Score = 37.5 bits (83), Expect = 0.13
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A N++ ++ L + GAD ++ D G TPLH A A+C F I L+ +GA+V +
Sbjct: 411 AAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCI-ETLVTTGANVNETDD 469
Query: 61 DGELPVDIAESDAMADLLQKVI---DEKGVDCEKSRNAEVDTLMSDAREWALHGYV--EV 115
G + A + M D + ++ + + E++R + + + E+ L +
Sbjct: 470 WGRTALHYAAASDM-DRNKTILGNAHDNSEELERARELK-EKEATLCLEFLLQNDANPSI 527
Query: 116 RDLKTGGTPLHVAAAKGY 133
RD K G +H AAA G+
Sbjct: 528 RD-KEGYNSIHYAAAYGH 544
Score = 35.1 bits (77), Expect = 0.70
Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 1/107 (0%)
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T PL A G + + L+ D + +D E TPLH AA G E LL+ GA
Sbjct: 7 TDQPPLVQAIFSGDPEEIRMLIHKTE-DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
+ K+ T L S S + +K VN + P H
Sbjct: 66 RVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLH 112
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 91.9 bits (218), Expect = 6e-18
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+V L+ HGA+V D +G+TPLHA AS G I++ ++LL G ++ +N G +
Sbjct: 160 HLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALH 219
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN--------AEVDTLMSDAREWALHGYVEVR-DL 118
IA + ++ ++ID G + + N A T + E ++ +V
Sbjct: 220 IACYNGQDAVVNELID-YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQS 278
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G +PLH+ A G ++TL+++ + DCVD +G TPLH AA +G + L+ G
Sbjct: 279 KDGKSPLHMTAVHGRFTRSQTLIQN-GGEIDCVDKDGNTPLHVAARYGHELLINTLITSG 337
Query: 179 AD 180
AD
Sbjct: 338 AD 339
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ +GA+VN+ +N G+TPLH A AS L+ +GADV + D
Sbjct: 221 ACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKD 280
Query: 62 GELPVDIAESDAMADLLQKVIDEKG-VDC-EKSRNAEVDTLMSDAREWALHGYVEV-RDL 118
G+ P+ + Q +I G +DC +K N + E ++ + D
Sbjct: 281 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADT 340
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA + D + LL + D D G T LHAAA G E LL
Sbjct: 341 AKCGIHSMFPLHLAALNAHSDCCRKLLSS-GFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD H K+ G+T L
Sbjct: 400 QSSGADFHKKDKCGRTPL 417
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 18/197 (9%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++E L+ GA VN DN TPLH + + L++ ADV A + + + P+ +A
Sbjct: 30 EIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVA 89
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL----------- 118
++ + +I R T + A AL+G+VE+ +L
Sbjct: 90 AANKAVKCAEVIIPLLSSVNVSDRGGR--TALHHA---ALNGHVEMVNLLLAKGANINAF 144
Query: 119 -KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K LH AA G++DV LL + A+ C D +G+TPLHAAA GQ LL
Sbjct: 145 DKKDRRALHWAAYMGHLDVV-ALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNL 203
Query: 178 GADPHLKNYSGQTCLDL 194
G + N G T L +
Sbjct: 204 GVEIDEINVYGNTALHI 220
Score = 67.3 bits (157), Expect = 1e-10
Identities = 59/190 (31%), Positives = 90/190 (47%), Gaps = 12/190 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
+E LV +GADVN +G +PLH TA G + ++ L+++G ++ V+ DG P+ +A
Sbjct: 264 LELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAAR 323
Query: 72 DAMADLLQKVIDEKGVDCEKS--------RNAEVDTLMSDAREWALHGY-VEVRDLKTGG 122
+LL + G D K A ++ R+ G+ ++ D K G
Sbjct: 324 YGH-ELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPD-KFGR 381
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T LH AAA G ++ K LL+ AD D G TPLH AA L+ GA+ +
Sbjct: 382 TCLHAAAAGGNVECIK-LLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVN 440
Query: 183 LKNYSGQTCL 192
+ G+T L
Sbjct: 441 ETDDWGRTAL 450
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/198 (23%), Positives = 94/198 (47%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ +++MV L+ GA++N D + LH A G + + L+ GA+V + G
Sbjct: 122 AALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG 181
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALHGYVEV---- 115
P+ A S+ ++++ +++ GV+ ++ N + + ++ ++ ++
Sbjct: 182 YTPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANV 240
Query: 116 -RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ G TPLH AAA + + LL + AD + +G +PLH A+ G+ + L
Sbjct: 241 NQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTL 300
Query: 175 LKFGADPHLKNYSGQTCL 192
++ G + + G T L
Sbjct: 301 IQNGGEIDCVDKDGNTPL 318
Score = 58.0 bits (134), Expect = 9e-08
Identities = 53/200 (26%), Positives = 89/200 (44%), Gaps = 11/200 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + +++V+ L+ G +++ + G T LH G ++ L++ GA+V N +
Sbjct: 187 AAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNN 246
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLMSD-----AREWAL---HGY 112
G P+ A + L +++ G D +S++ + M+ R L G
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
++ D K G TPLHVAA G+ + TL+ AD PLH AAL +
Sbjct: 307 IDCVD-KDGNTPLHVAARYGHELLINTLITS-GADTAKCGIHSMFPLHLAALNAHSDCCR 364
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL G + + G+TCL
Sbjct: 365 KLLSSGFEIDTPDKFGRTCL 384
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ DVN D+E TPLH A G I L+ SGA V A + P+ A +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 75 ADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGYVEVRDLKTGGTPLH 126
+ +Q +I + +N + ++ A + L V V D + G T LH
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSD-RGGRTALH 120
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
AA G++++ LL A+ + D + LH AA G + ALL+ GA+ K+
Sbjct: 121 HAALNGHVEMVNLLLAK-GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDK 179
Query: 187 SGQTCL 192
G T L
Sbjct: 180 KGYTPL 185
Score = 37.5 bits (83), Expect = 0.13
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 10/138 (7%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A N++ ++ L + GAD ++ D G TPLH A A+C F I L+ +GA+V +
Sbjct: 386 AAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCI-ETLVTTGANVNETDD 444
Query: 61 DGELPVDIAESDAMADLLQKVI---DEKGVDCEKSRNAEVDTLMSDAREWALHGYV--EV 115
G + A + M D + ++ + + E++R + + + E+ L +
Sbjct: 445 WGRTALHYAAASDM-DRNKTILGNAHDNSEELERARELK-EKEATLCLEFLLQNDANPSI 502
Query: 116 RDLKTGGTPLHVAAAKGY 133
RD K G +H AAA G+
Sbjct: 503 RD-KEGYNSIHYAAAYGH 519
Score = 37.1 bits (82), Expect = 0.17
Identities = 45/183 (24%), Positives = 77/183 (42%), Gaps = 23/183 (12%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D L++ G +++ D G T LHA A+ G + + L SGAD + G
Sbjct: 354 AALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCG 413
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A ++ ++ ++ + A V+ D ALH Y D+
Sbjct: 414 RTPLHYAAANCHFHCIETLV---------TTGANVNE-TDDWGRTALH-YAAASDMDRNK 462
Query: 123 TPLHVAAAKG-YIDVAKTLLED----C-------NADPDCVDYEGWTPLHAAALWGQKEA 170
T L A ++ A+ L E C +A+P D EG+ +H AA +G ++
Sbjct: 463 TILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQC 522
Query: 171 AAL 173
L
Sbjct: 523 LEL 525
Score = 34.7 bits (76), Expect = 0.93
Identities = 25/80 (31%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + +D E TPLH AA G E LL+ GA + K+ T L S S +
Sbjct: 8 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV 67
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
+K VN + P H
Sbjct: 68 LIKHSADVNARDKNWQTPLH 87
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 90.2 bits (214), Expect = 2e-17
Identities = 59/182 (32%), Positives = 95/182 (52%), Gaps = 11/182 (6%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+V L+ HGA+V D +G+TPLHA AS G I++ ++LL G ++ +N G +
Sbjct: 160 HLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALH 219
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRN--------AEVDTLMSDAREWALHGYVEVR-DL 118
IA + ++ ++ID G + + N A T + E ++ +V
Sbjct: 220 IACYNGQDAVVNELID-YGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQS 278
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G +PLH+ A G ++TL+++ + DCVD +G TPLH AA +G + L G
Sbjct: 279 KDGKSPLHMTAVHGRFTRSQTLIQN-GGEIDCVDKDGNTPLHVAARYGHELLINTLRTSG 337
Query: 179 AD 180
AD
Sbjct: 338 AD 339
Score = 76.6 bits (180), Expect = 2e-13
Identities = 64/198 (32%), Positives = 90/198 (45%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNYD 61
AC + +V L+ +GA+VN+ +N G+TPLH A AS L+ +GADV + D
Sbjct: 221 ACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKD 280
Query: 62 GELPVDIAESDAMADLLQKVIDEKG-VDC-EKSRNAEVDTLMSDAREWALHGY-VEVRDL 118
G+ P+ + Q +I G +DC +K N + E ++ D
Sbjct: 281 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADT 340
Query: 119 KTGGT----PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
G PLH+AA + D + LL + D D G T LHAAA G E LL
Sbjct: 341 AKCGIHSMFPLHLAALNAHSDCCRKLLSS-GFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD H K+ G+T L
Sbjct: 400 QSSGADFHKKDKCGRTPL 417
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 18/197 (9%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++E L+ GA VN DN TPLH + + L++ ADV A + + + P+ +A
Sbjct: 30 EIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVA 89
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL----------- 118
++ + +I R T + A AL+G+VE+ +L
Sbjct: 90 AANKAVKCAEVIIPLLSSVNVSDRGGR--TALHHA---ALNGHVEMVNLLLAKGANINAF 144
Query: 119 -KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K LH AA G++DV LL + A+ C D +G+TPLHAAA GQ LL
Sbjct: 145 DKKDRRALHWAAYMGHLDVV-ALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNL 203
Query: 178 GADPHLKNYSGQTCLDL 194
G + N G T L +
Sbjct: 204 GVEIDEINVYGNTALHI 220
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/198 (23%), Positives = 94/198 (47%), Gaps = 9/198 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ +++MV L+ GA++N D + LH A G + + L+ GA+V + G
Sbjct: 122 AALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG 181
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR---NAEVDTLMSDAREWALHGYVEV---- 115
P+ A S+ ++++ +++ GV+ ++ N + + ++ ++ ++
Sbjct: 182 YTPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANV 240
Query: 116 -RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ G TPLH AAA + + LL + AD + +G +PLH A+ G+ + L
Sbjct: 241 NQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTL 300
Query: 175 LKFGADPHLKNYSGQTCL 192
++ G + + G T L
Sbjct: 301 IQNGGEIDCVDKDGNTPL 318
Score = 60.9 bits (141), Expect = 1e-08
Identities = 58/200 (29%), Positives = 98/200 (49%), Gaps = 11/200 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLH-ATASCGFISIARYLLESGADVAAVNY 60
+A N++ ++ L + GAD ++ D G TPLH A A+C F I L+ +GA+V +
Sbjct: 386 AAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCI-ETLVTTGANVNETDD 444
Query: 61 DGELPVDIAESDAMADLLQKVI---DEKGVDCEKSRNAEVDTLMSDAREWALHGYV--EV 115
G + A + M D + ++ + + E++R + + + E+ L +
Sbjct: 445 WGRTALHYAAASDM-DRNKTILGNAHDNSEELERARELK-EKEATLCLEFLLQNDANPSI 502
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW-TPLHAAALWGQKEAAALL 174
RD K G +H AAA G+ + LLE N+ + D +PLH AA G +A +L
Sbjct: 503 RD-KEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVL 561
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ D +++ G+T LDL
Sbjct: 562 LQSLVDLDIRDEKGRTALDL 581
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ DVN D+E TPLH A G I L+ SGA V A + P+ A +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 75 ADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA--------LHGYVEVRDLKTGGTPLH 126
+ +Q +I + +N + ++ A + L V V D + G T LH
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSD-RGGRTALH 120
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
AA G++++ LL A+ + D + LH AA G + ALL+ GA+ K+
Sbjct: 121 HAALNGHVEMVNLLLAK-GANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDK 179
Query: 187 SGQTCL 192
G T L
Sbjct: 180 KGYTPL 185
Score = 56.8 bits (131), Expect = 2e-07
Identities = 52/200 (26%), Positives = 88/200 (44%), Gaps = 11/200 (5%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + +++V+ L+ G +++ + G T LH G ++ L++ GA+V N +
Sbjct: 187 AAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNN 246
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCE-KSRNAEVDTLMSD-----AREWAL---HGY 112
G P+ A + L +++ G D +S++ + M+ R L G
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
++ D K G TPLHVAA G+ ++ L AD PLH AAL +
Sbjct: 307 IDCVD-KDGNTPLHVAARYGH-ELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCR 364
Query: 173 LLLKFGADPHLKNYSGQTCL 192
LL G + + G+TCL
Sbjct: 365 KLLSSGFEIDTPDKFGRTCL 384
Score = 51.6 bits (118), Expect = 8e-06
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 18/196 (9%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLE---SG---ADVAAVNYDGELP 65
+EFL+ + A+ + D EG+ +H A+ G LLE SG +D A L
Sbjct: 490 LEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLA 549
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE------VRDLK 119
A+ LLQ ++D D EK R A +D + + V+D
Sbjct: 550 AYNGHHQALEVLLQSLVDLDIRD-EKGRTA-LDLAAFKGHTECVEALINPGASIFVKDNV 607
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDY---EGWTPLHAAALWGQKEAAALLLK 176
T TPLH + G+ + LLE + +P+ VD +G TPL A +G +A +LLL+
Sbjct: 608 TKRTPLHASVINGHTLCLRLLLEIAD-NPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLE 666
Query: 177 FGADPHLKNYSGQTCL 192
A+ + G T L
Sbjct: 667 KEANVDTVDILGCTAL 682
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V+V+D K G TPL +A A G+ID LLE A+ D VD G T LH + G +E
Sbjct: 638 VDVKDAK-GQTPLMLAVAYGHIDAVSLLLEK-EANVDTVDILGCTALHRGIMTGHEECVQ 695
Query: 173 LLLKFGADPHLKNYSGQTCLDLVDP-SISSWLEE 205
+LL+ K+ G+T L ++WL E
Sbjct: 696 MLLEQEVSILCKDSRGRTPLHYAAARGHATWLSE 729
Score = 49.6 bits (113), Expect = 3e-05
Identities = 56/204 (27%), Positives = 85/204 (41%), Gaps = 14/204 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A ++D V L+ A+V+ D G T LH G + LLE + +
Sbjct: 650 MLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDS 709
Query: 61 DGELPVDIAESDA----MADLLQKVIDEKGVDCEKSRNAEVDTL---MSDAREWALHGYV 113
G P+ A + +++LLQ + E+ DC N L + E + +
Sbjct: 710 RGRTPLHYAAARGHATWLSELLQMALSEE--DCCFKDNQGYTPLHWACYNGNENCIEVLL 767
Query: 114 EVRDLK--TGG--TPLHVAAAKGYIDVAKTLLEDCNAD-PDCVDYEGWTPLHAAALWGQK 168
E + + G TPLH A + + A LL ++ C D +G TPL AAA
Sbjct: 768 EQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHV 827
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E LLL+ A + + SG+T L
Sbjct: 828 ECLQLLLRHSAPVNAVDNSGKTAL 851
Score = 40.7 bits (91), Expect = 0.014
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 23/186 (12%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D L++ G +++ D G T LHA A+ G + + L SGAD + G
Sbjct: 354 AALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCG 413
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A ++ ++ ++ + A V+ D ALH Y D+
Sbjct: 414 RTPLHYAAANCHFHCIETLV---------TTGANVNE-TDDWGRTALH-YAAASDMDRNK 462
Query: 123 TPLHVAAAKG-YIDVAKTLLED----C-------NADPDCVDYEGWTPLHAAALWGQKEA 170
T L A ++ A+ L E C +A+P D EG+ +H AA +G ++
Sbjct: 463 TILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQC 522
Query: 171 AALLLK 176
LLL+
Sbjct: 523 LELLLE 528
Score = 37.9 bits (84), Expect = 0.099
Identities = 48/169 (28%), Positives = 64/169 (37%), Gaps = 10/169 (5%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA---ESDAMADLLQKVI 82
DN+G+TPLH G + LLE + + P+ A + A LL I
Sbjct: 744 DNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIG-NPFTPLHCAIINDHGNCASLLLGAI 802
Query: 83 DEKGVDC--EKSRNAEVDTLMSDAREWA---LHGYVEVRDLKTGG-TPLHVAAAKGYIDV 136
D V C +K R +D E L V + G T L +AA G
Sbjct: 803 DSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGA 862
Query: 137 AKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
L+ AD D + TPLH A G ++ A L+L D L N
Sbjct: 863 VDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLIN 911
Score = 34.7 bits (76), Expect = 0.93
Identities = 25/80 (31%), Positives = 33/80 (41%)
Query: 147 DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEA 206
D + +D E TPLH AA G E LL+ GA + K+ T L S S +
Sbjct: 8 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV 67
Query: 207 ALKAPRRVNNNKRKLSPPRH 226
+K VN + P H
Sbjct: 68 LIKHSADVNARDKNWQTPLH 87
Score = 34.7 bits (76), Expect = 0.93
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESG-ADVAAVNY 60
+A D+++ ++ L+ H A VN DN G T L A G L+ S AD+ +
Sbjct: 820 AAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDK 879
Query: 61 DGELPVDIAESDAMADLLQKVIDE 84
D P+ +A S ++D+
Sbjct: 880 DLNTPLHLACSKGHEKCALLILDK 903
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 89.4 bits (212), Expect = 3e-17
Identities = 66/204 (32%), Positives = 95/204 (46%), Gaps = 18/204 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A D D+ L+ HGAD NR D +GW PLH A G AR LL+ GA V A +G
Sbjct: 402 AAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREG 461
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG- 121
P+ +A + ++ + ++ + AE T + A A G+V + L T
Sbjct: 462 WTPLHLAAQNNFENVARLLVSRQA--DPNLHEAEGKTPLHVA---AYFGHVSLVKLLTSQ 516
Query: 122 -----------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEA 170
TPLH+A +G + + LL+ A PD +D G+ PLH AA G+
Sbjct: 517 GAELDAQQRNLRTPLHLAVERGKVRAIQHLLKS-GAVPDALDQSGYGPLHTAAARGKYLI 575
Query: 171 AALLLKFGADPHLKNYSGQTCLDL 194
+LL++GA L + G T L L
Sbjct: 576 CKMLLRYGASLELPTHQGWTPLHL 599
Score = 83.4 bits (197), Expect = 2e-15
Identities = 59/192 (30%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ LV+ AD N + EG TPLH A G +S+ + L GA++ A + P+ +A
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Query: 70 ESDAMADLLQKVIDEKGVD--CEKSRNAEVDTLMSDAREWA---LHGYVEVRDLKT--GG 122
+Q ++ V ++S + T + + L Y +L T G
Sbjct: 535 VERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGW 594
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA KG++++ LL + +A+ + WTPLH AA G++ + LL+ GADP+
Sbjct: 595 TPLHLAAYKGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPN 653
Query: 183 LKNYSGQTCLDL 194
SG T L L
Sbjct: 654 AAEQSGWTPLHL 665
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/191 (28%), Positives = 85/191 (44%), Gaps = 10/191 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++ +V+ L + GA+++ TPLH G + ++LL+SGA A++ G P+
Sbjct: 506 HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLH 565
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEVRDL-K 119
A + L+ K++ G E + L A + L + + L
Sbjct: 566 TAAARGKY-LICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGA 624
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLH+AA G V LL+ C ADP+ + GWTPLH A + LL+ A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQ-CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHA 683
Query: 180 DPHLKNYSGQT 190
+ H +N G T
Sbjct: 684 NVHARNKVGWT 694
Score = 62.5 bits (145), Expect = 4e-09
Identities = 55/171 (32%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVI----DEKG 86
TPLH + G + R LL DV G P+ IA D DL ++ D
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 87 VDCEKSRNAEVDTLMSD---AREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLED 143
VD + D AR HG + G TPLH+AA + +VA+ LL
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVAR-LLVS 482
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
ADP+ + EG TPLH AA +G LL GA+ + + +T L L
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHL 533
Score = 58.0 bits (134), Expect = 9e-08
Identities = 55/188 (29%), Positives = 78/188 (41%), Gaps = 8/188 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+++ V L+ H DV+ G+TPL A + LL GAD V+ DG P+
Sbjct: 374 SVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLH 433
Query: 68 IAESDAMADLLQKVIDEKG-VDCEKSRN------AEVDTLMSDAREWALHGYVEVRDLKT 120
A + + ++D VD ++ A + + AR
Sbjct: 434 FAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAE 493
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVAA G++ + K LL A+ D TPLH A G+ A LLK GA
Sbjct: 494 GKTPLHVAAYFGHVSLVK-LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAV 552
Query: 181 PHLKNYSG 188
P + SG
Sbjct: 553 PDALDQSG 560
Score = 48.0 bits (109), Expect = 9e-05
Identities = 49/191 (25%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
++ L+ GA + D G+ PLH A+ G I + LL GA + + G P+ +A
Sbjct: 543 IQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 72 DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR---EWALHGYVEV-----RDLKTGGT 123
+++ ++ E + L AR E + ++ ++G T
Sbjct: 603 KGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWT 661
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH+A + LLE +A+ + GWTP H AAL G +L++ GA L
Sbjct: 662 PLHLAVQRSTFLSVINLLEH-HANVHARNKVGWTPAHLAALKGNTAILKVLVEAGA--QL 718
Query: 184 KNYSGQTCLDL 194
G +C L
Sbjct: 719 DVQDGVSCTPL 729
Score = 45.6 bits (103), Expect = 5e-04
Identities = 51/186 (27%), Positives = 74/186 (39%), Gaps = 29/186 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +L+++ L A++ WTPLH A G ++ LL+ GAD A G
Sbjct: 600 AAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSG 659
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A ++S V L+ H V R+ K G
Sbjct: 660 WTPLHLA-------------------VQRSTFLSVINLLEH------HANVHARN-KVGW 693
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TP H+AA KG + K L+E A D D TPL AL +K+ L+ G +P
Sbjct: 694 TPAHLAALKGNTAILKVLVE-AGAQLDVQDGVSCTPLQ-LALRSRKQGIMSFLE-GKEPS 750
Query: 183 LKNYSG 188
+ G
Sbjct: 751 VATLGG 756
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 89.4 bits (212), Expect = 3e-17
Identities = 66/204 (32%), Positives = 95/204 (46%), Gaps = 18/204 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A D D+ L+ HGAD NR D +GW PLH A G AR LL+ GA V A +G
Sbjct: 402 AAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREG 461
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG- 121
P+ +A + ++ + ++ + AE T + A A G+V + L T
Sbjct: 462 WTPLHLAAQNNFENVARLLVSRQA--DPNLHEAEGKTPLHVA---AYFGHVSLVKLLTSQ 516
Query: 122 -----------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEA 170
TPLH+A +G + + LL+ A PD +D G+ PLH AA G+
Sbjct: 517 GAELDAQQRNLRTPLHLAVERGKVRAIQHLLKS-GAVPDALDQSGYGPLHTAAARGKYLI 575
Query: 171 AALLLKFGADPHLKNYSGQTCLDL 194
+LL++GA L + G T L L
Sbjct: 576 CKMLLRYGASLELPTHQGWTPLHL 599
Score = 83.4 bits (197), Expect = 2e-15
Identities = 59/192 (30%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ LV+ AD N + EG TPLH A G +S+ + L GA++ A + P+ +A
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Query: 70 ESDAMADLLQKVIDEKGVD--CEKSRNAEVDTLMSDAREWA---LHGYVEVRDLKT--GG 122
+Q ++ V ++S + T + + L Y +L T G
Sbjct: 535 VERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGW 594
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA KG++++ LL + +A+ + WTPLH AA G++ + LL+ GADP+
Sbjct: 595 TPLHLAAYKGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPN 653
Query: 183 LKNYSGQTCLDL 194
SG T L L
Sbjct: 654 AAEQSGWTPLHL 665
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/191 (28%), Positives = 85/191 (44%), Gaps = 10/191 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++ +V+ L + GA+++ TPLH G + ++LL+SGA A++ G P+
Sbjct: 506 HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLH 565
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEVRDL-K 119
A + L+ K++ G E + L A + L + + L
Sbjct: 566 TAAARGKY-LICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGA 624
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLH+AA G V LL+ C ADP+ + GWTPLH A + LL+ A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQ-CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHA 683
Query: 180 DPHLKNYSGQT 190
+ H +N G T
Sbjct: 684 NVHARNKVGWT 694
Score = 62.5 bits (145), Expect = 4e-09
Identities = 55/171 (32%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVI----DEKG 86
TPLH + G + R LL DV G P+ IA D DL ++ D
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 87 VDCEKSRNAEVDTLMSD---AREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLED 143
VD + D AR HG + G TPLH+AA + +VA+ LL
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVAR-LLVS 482
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
ADP+ + EG TPLH AA +G LL GA+ + + +T L L
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHL 533
Score = 58.0 bits (134), Expect = 9e-08
Identities = 55/188 (29%), Positives = 78/188 (41%), Gaps = 8/188 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+++ V L+ H DV+ G+TPL A + LL GAD V+ DG P+
Sbjct: 374 SVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLH 433
Query: 68 IAESDAMADLLQKVIDEKG-VDCEKSRN------AEVDTLMSDAREWALHGYVEVRDLKT 120
A + + ++D VD ++ A + + AR
Sbjct: 434 FAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAE 493
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVAA G++ + K LL A+ D TPLH A G+ A LLK GA
Sbjct: 494 GKTPLHVAAYFGHVSLVK-LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAV 552
Query: 181 PHLKNYSG 188
P + SG
Sbjct: 553 PDALDQSG 560
Score = 48.0 bits (109), Expect = 9e-05
Identities = 49/191 (25%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
++ L+ GA + D G+ PLH A+ G I + LL GA + + G P+ +A
Sbjct: 543 IQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 72 DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR---EWALHGYVEV-----RDLKTGGT 123
+++ ++ E + L AR E + ++ ++G T
Sbjct: 603 KGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWT 661
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH+A + LLE +A+ + GWTP H AAL G +L++ GA L
Sbjct: 662 PLHLAVQRSTFLSVINLLEH-HANVHARNKVGWTPAHLAALKGNTAILKVLVEAGA--QL 718
Query: 184 KNYSGQTCLDL 194
G +C L
Sbjct: 719 DVQDGVSCTPL 729
Score = 45.6 bits (103), Expect = 5e-04
Identities = 51/186 (27%), Positives = 74/186 (39%), Gaps = 29/186 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +L+++ L A++ WTPLH A G ++ LL+ GAD A G
Sbjct: 600 AAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSG 659
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A ++S V L+ H V R+ K G
Sbjct: 660 WTPLHLA-------------------VQRSTFLSVINLLEH------HANVHARN-KVGW 693
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TP H+AA KG + K L+E A D D TPL AL +K+ L+ G +P
Sbjct: 694 TPAHLAALKGNTAILKVLVE-AGAQLDVQDGVSCTPLQ-LALRSRKQGIMSFLE-GKEPS 750
Query: 183 LKNYSG 188
+ G
Sbjct: 751 VATLGG 756
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 89.4 bits (212), Expect = 3e-17
Identities = 66/204 (32%), Positives = 95/204 (46%), Gaps = 18/204 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A D D+ L+ HGAD NR D +GW PLH A G AR LL+ GA V A +G
Sbjct: 402 AAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREG 461
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG- 121
P+ +A + ++ + ++ + AE T + A A G+V + L T
Sbjct: 462 WTPLHLAAQNNFENVARLLVSRQA--DPNLHEAEGKTPLHVA---AYFGHVSLVKLLTSQ 516
Query: 122 -----------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEA 170
TPLH+A +G + + LL+ A PD +D G+ PLH AA G+
Sbjct: 517 GAELDAQQRNLRTPLHLAVERGKVRAIQHLLKS-GAVPDALDQSGYGPLHTAAARGKYLI 575
Query: 171 AALLLKFGADPHLKNYSGQTCLDL 194
+LL++GA L + G T L L
Sbjct: 576 CKMLLRYGASLELPTHQGWTPLHL 599
Score = 83.4 bits (197), Expect = 2e-15
Identities = 59/192 (30%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ LV+ AD N + EG TPLH A G +S+ + L GA++ A + P+ +A
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Query: 70 ESDAMADLLQKVIDEKGVD--CEKSRNAEVDTLMSDAREWA---LHGYVEVRDLKT--GG 122
+Q ++ V ++S + T + + L Y +L T G
Sbjct: 535 VERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGW 594
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA KG++++ LL + +A+ + WTPLH AA G++ + LL+ GADP+
Sbjct: 595 TPLHLAAYKGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPN 653
Query: 183 LKNYSGQTCLDL 194
SG T L L
Sbjct: 654 AAEQSGWTPLHL 665
Score = 64.1 bits (149), Expect = 1e-09
Identities = 54/191 (28%), Positives = 85/191 (44%), Gaps = 10/191 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++ +V+ L + GA+++ TPLH G + ++LL+SGA A++ G P+
Sbjct: 506 HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLH 565
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEVRDL-K 119
A + L+ K++ G E + L A + L + + L
Sbjct: 566 TAAARGKY-LICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGA 624
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLH+AA G V LL+ C ADP+ + GWTPLH A + LL+ A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQ-CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHA 683
Query: 180 DPHLKNYSGQT 190
+ H +N G T
Sbjct: 684 NVHARNKVGWT 694
Score = 62.5 bits (145), Expect = 4e-09
Identities = 55/171 (32%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVI----DEKG 86
TPLH + G + R LL DV G P+ IA D DL ++ D
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 87 VDCEKSRNAEVDTLMSD---AREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLED 143
VD + D AR HG + G TPLH+AA + +VA+ LL
Sbjct: 424 VDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVAR-LLVS 482
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
ADP+ + EG TPLH AA +G LL GA+ + + +T L L
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHL 533
Score = 58.0 bits (134), Expect = 9e-08
Identities = 55/188 (29%), Positives = 78/188 (41%), Gaps = 8/188 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+++ V L+ H DV+ G+TPL A + LL GAD V+ DG P+
Sbjct: 374 SVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLH 433
Query: 68 IAESDAMADLLQKVIDEKG-VDCEKSRN------AEVDTLMSDAREWALHGYVEVRDLKT 120
A + + ++D VD ++ A + + AR
Sbjct: 434 FAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAE 493
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVAA G++ + K LL A+ D TPLH A G+ A LLK GA
Sbjct: 494 GKTPLHVAAYFGHVSLVK-LLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAV 552
Query: 181 PHLKNYSG 188
P + SG
Sbjct: 553 PDALDQSG 560
Score = 48.0 bits (109), Expect = 9e-05
Identities = 49/191 (25%), Positives = 80/191 (41%), Gaps = 12/191 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
++ L+ GA + D G+ PLH A+ G I + LL GA + + G P+ +A
Sbjct: 543 IQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 72 DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR---EWALHGYVEV-----RDLKTGGT 123
+++ ++ E + L AR E + ++ ++G T
Sbjct: 603 KGHLEIIH-LLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWT 661
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH+A + LLE +A+ + GWTP H AAL G +L++ GA L
Sbjct: 662 PLHLAVQRSTFLSVINLLEH-HANVHARNKVGWTPAHLAALKGNTAILKVLVEAGA--QL 718
Query: 184 KNYSGQTCLDL 194
G +C L
Sbjct: 719 DVQDGVSCTPL 729
Score = 45.6 bits (103), Expect = 5e-04
Identities = 51/186 (27%), Positives = 74/186 (39%), Gaps = 29/186 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +L+++ L A++ WTPLH A G ++ LL+ GAD A G
Sbjct: 600 AAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSG 659
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A ++S V L+ H V R+ K G
Sbjct: 660 WTPLHLA-------------------VQRSTFLSVINLLEH------HANVHARN-KVGW 693
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TP H+AA KG + K L+E A D D TPL AL +K+ L+ G +P
Sbjct: 694 TPAHLAALKGNTAILKVLVE-AGAQLDVQDGVSCTPLQ-LALRSRKQGIMSFLE-GKEPS 750
Query: 183 LKNYSG 188
+ G
Sbjct: 751 VATLGG 756
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 88.2 bits (209), Expect = 7e-17
Identities = 62/174 (35%), Positives = 87/174 (50%), Gaps = 10/174 (5%)
Query: 29 GWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVD 88
G T LH A G + RYL++ GA V A D + P+ I+ AD++Q+++ ++G
Sbjct: 10 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL-QQGAS 68
Query: 89 CEKSRNAEVDTLMSDARE-------WAL-HGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+ + L ARE + L HG K G TPLHVAA G ++VA L
Sbjct: 69 PNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 128
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L+ +A PD G TPLH AA + ++ A LLL GA PH +G T L +
Sbjct: 129 LQK-SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHI 181
Score = 81.8 bits (193), Expect = 6e-15
Identities = 59/192 (30%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+V+ L+ GA N G+TPLH +A G +A +LL+ GA ++ G P+ +A
Sbjct: 57 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 116
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS---DAREWAL----HGYVEVRDLKTGG 122
++ ++ + ++ ++ D ++ AL G K G
Sbjct: 117 AKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 176
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA K +D+A TLLE AD + V +G +H AA G + +LLL A+ +
Sbjct: 177 TPLHIAAKKNQMDIATTLLE-YGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVN 235
Query: 183 LKNYSGQTCLDL 194
L N SG T L L
Sbjct: 236 LSNKSGLTPLHL 247
Score = 71.7 bits (168), Expect = 7e-12
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LLE GAD AV G V
Sbjct: 153 DNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 212
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH---------GYVEVRD 117
+A + D++ ++ + + S + + L A+E ++ +V+ +
Sbjct: 213 HLAAQEGHVDMVSLLLG-RNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ- 270
Query: 118 LKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF 177
K G TPLHV G I + LL+ +A + G+TPLH AA G +LL+
Sbjct: 271 TKMGYTPLHVGCHYGNIKIVNFLLQH-SAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 329
Query: 178 GADPHLKNYSGQTCLDL 194
A P+ +G T L +
Sbjct: 330 NASPNELTVNGNTALGI 346
Score = 47.2 bits (107), Expect = 2e-04
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ E LV GA V+ G+TPLH G I I +LL+ A V A +G
Sbjct: 248 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG 307
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ ++ E + N +T + AR GY+ V D
Sbjct: 308 YTPLHQAAQQGHTHIINVLLQNNASPNELTVNG--NTALGIARRL---GYISVVD 357
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 9/146 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++DMV L+ A+VN + G TPLH A +++A L+ GA V A G
Sbjct: 215 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 274
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-------GYVEV 115
P+ + ++ ++ K++N L A++ H
Sbjct: 275 YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNG-YTPLHQAAQQGHTHIINVLLQNNASP 333
Query: 116 RDLK-TGGTPLHVAAAKGYIDVAKTL 140
+L G T L +A GYI V TL
Sbjct: 334 NELTVNGNTALGIARRLGYISVVDTL 359
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 85.8 bits (203), Expect = 4e-16
Identities = 59/192 (30%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V+ L+ H A + G+TPLH +A G + +A LLE+GA + G P+ +A
Sbjct: 511 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA 570
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS---DAREWAL----HGYVEVRDLKTGG 122
D+ + ++ + +N ++ D ++ AL G K G
Sbjct: 571 AKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA K + +A TLL + A+ + V +G TPLH A+ G + LLL GA+ H
Sbjct: 631 TPLHIAAKKNQMQIASTLL-NYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH 689
Query: 183 LKNYSGQTCLDL 194
+ SG T L L
Sbjct: 690 MSTKSGLTSLHL 701
Score = 82.2 bits (194), Expect = 5e-15
Identities = 64/195 (32%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L++V L+ +GA + + G T LH A G + + R LL +GA V A + + P+
Sbjct: 443 HLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 502
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH--------GYVEVRDLK 119
IA +++Q ++ + N +S ARE + G K
Sbjct: 503 IASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGAAHSLATK 561
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G +DVAK LL+ A D G TPLH AA + ++ A LLL+ GA
Sbjct: 562 KGFTPLHVAAKYGSLDVAKLLLQR-RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGA 620
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 621 SPHATAKNGYTPLHI 635
Score = 79.4 bits (187), Expect = 3e-14
Identities = 64/203 (31%), Positives = 94/203 (46%), Gaps = 16/203 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LV GA++N G+TPL+ A I + +YLLE+GA+ + DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163
Query: 63 ELPVDIA----ESDAMADLLQKVIDEKG--------VDCEKSRNAEVDTLMSDAREWALH 110
P+ +A + A+A LL+ D KG + K L+ + +
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN--DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQ 221
Query: 111 GYVEV-RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
+ V R ++G TPLH+AA G ++VA TLL + A D G TPLH A+ G
Sbjct: 222 SKMMVNRTTESGFTPLHIAAHYGNVNVA-TLLLNRGAAVDFTARNGITPLHVASKRGNTN 280
Query: 170 AAALLLKFGADPHLKNYSGQTCL 192
LLL G K G T L
Sbjct: 281 MVKLLLDRGGQIDAKTRDGLTPL 303
Score = 78.6 bits (185), Expect = 6e-14
Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 8/197 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E LV +GA + G TP+H A G ++I LL++GA N G
Sbjct: 405 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 464
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE-----VDTLMSDAREWALHGYVEVRD 117
E + +A ++++ ++ + ++R + L L ++ D
Sbjct: 465 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD 524
Query: 118 LKT--GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
T G TPLH++A +G +DVA LLE A +G+TPLH AA +G + A LLL
Sbjct: 525 AATTNGYTPLHISAREGQVDVASVLLE-AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583
Query: 176 KFGADPHLKNYSGQTCL 192
+ A +G T L
Sbjct: 584 QRRAAADSAGKNGLTPL 600
Score = 77.8 bits (183), Expect = 1e-13
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 10/194 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LL GA+ V G P+
Sbjct: 607 DNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL 666
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRDL 118
+A + D++ ++D KG + S + + +L A+E HG +
Sbjct: 667 HLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHT 725
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G TPL VA G + + LL+ A+ + G+TPLH AA G +LL+ G
Sbjct: 726 KLGYTPLIVACHYGNVKMVNFLLKQ-GANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Query: 179 ADPHLKNYSGQTCL 192
A P+ +G T L
Sbjct: 785 AKPNATTANGNTAL 798
Score = 75.8 bits (178), Expect = 4e-13
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 10/232 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ G ++ +G TPLH A G + LLE GA + A +G P+
Sbjct: 278 NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH 337
Query: 68 IAESDAMADLLQKVIDEKG----VDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDLK 119
+A + ++ ++ K V + V R L R L
Sbjct: 338 MAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN 397
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + L++ A + G TP+H AA G LLL+ GA
Sbjct: 398 -GFTPLHIACKKNRIKVMELLVK-YGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P + N G+T L + + + L+ V+ R+ P H R+
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 507
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 10/181 (5%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
VNR G+TPLH A G +++A LL GA V +G P+ +A ++++ +
Sbjct: 226 VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLL 285
Query: 82 IDEKGVDCEKSRNAEVDTLMSDAR-------EWALH-GYVEVRDLKTGGTPLHVAAAKGY 133
+D G K+R+ + L AR E L G + K G +PLH+AA +
Sbjct: 286 LDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 344
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
++ K LL+ A D V + T LH AA G LLL A+P+ + +G T L
Sbjct: 345 VECVKHLLQH-KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLH 403
Query: 194 L 194
+
Sbjct: 404 I 404
Score = 63.7 bits (148), Expect = 2e-09
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 8/190 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+++ L+ GA V+ G TPLH + G ++ + LL+ G + A DG P+
Sbjct: 245 NVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKTG 121
A +++ +++ +++N M+ + + L V D+
Sbjct: 305 CAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLD 364
Query: 122 G-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
T LHVAA G+ V K LL D A+P+ G+TPLH A + + LL+K+GA
Sbjct: 365 YLTALHVAAHCGHYRVTKLLL-DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGAS 423
Query: 181 PHLKNYSGQT 190
SG T
Sbjct: 424 IQAITESGLT 433
Score = 59.3 bits (137), Expect = 4e-08
Identities = 51/173 (29%), Positives = 81/173 (46%), Gaps = 27/173 (15%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+++ V+ L+ H A V+ + T LH A CG + + LL+ A+ A +G P+
Sbjct: 343 DHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPL 402
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ +G ++G TP+H
Sbjct: 403 HIA-------------------CKKNRIKVMELLVK-------YGASIQAITESGLTPIH 436
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
VAA G++++ LL++ A PD + G T LH AA GQ E LL+ GA
Sbjct: 437 VAAFMGHLNIVLLLLQN-GASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+ + L+ A + G TPLH A +A LLE GA A +G P+
Sbjct: 575 SLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH 634
Query: 68 IA----ESDAMADLLQ-----KVIDEKGVD----CEKSRNAEVDTLMSDAREWALHGYVE 114
IA + + LL ++ ++GV + + ++ TL+ D + +H
Sbjct: 635 IAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD-KGANIH---- 689
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
K+G T LH+AA + ++VA L + AD D G+TPL A +G + L
Sbjct: 690 -MSTKSGLTSLHLAAQEDKVNVADILTKH-GADQDAHTKLGYTPLIVACHYGNVKMVNFL 747
Query: 175 LKFGADPHLKNYSGQTCL 192
LK GA+ + K +G T L
Sbjct: 748 LKQGANVNAKTKNGYTPL 765
Score = 55.6 bits (128), Expect = 5e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 27/169 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
NLD V + G D+N + G LH A G + + + LL G+ V + G +
Sbjct: 43 NLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALH 102
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
IA A+++ KV+ ++G + NA+ + G TPL++
Sbjct: 103 IASLAGQAEVV-KVLVKEGANI----NAQ---------------------SQNGFTPLYM 136
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
AA + +IDV K LLE+ A+ +G+TPL A G +A A+LL+
Sbjct: 137 AAQENHIDVVKYLLEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLE 184
Score = 55.2 bits (127), Expect = 6e-07
Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 12/235 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++ +V+ L+ G+ V+ +G T LH + G + + L++ GA++ A + +G
Sbjct: 71 AAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNG 130
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A + D++ K + E G + + L ++ + + T G
Sbjct: 131 FTPLYMAAQENHIDVV-KYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKG 189
Query: 123 ----TPLHVAAAKGYIDVAKTLLE-DCNADPDC------VDYEGWTPLHAAALWGQKEAA 171
LH+AA K A LL+ D NAD G+TPLH AA +G A
Sbjct: 190 KVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVA 249
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
LLL GA +G T L + ++ + + L +++ R P H
Sbjct: 250 TLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N+ MV FL+ GA+VN G+TPLH A G I LL+ GA A +G
Sbjct: 735 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANG 794
Query: 63 ELPVDIAES---DAMADLLQKVIDE 84
+ IA+ ++ D L+ V +E
Sbjct: 795 NTALAIAKRLGYISVVDTLKVVTEE 819
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ + L HGAD + G+TPL G + + +LL+ GA+V A +G
Sbjct: 702 AAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNG 761
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ V+ + G + A +T ++ A+ GY+ V D
Sbjct: 762 YTPLHQAAQQGHTHII-NVLLQHGAK-PNATTANGNTALAIAKRL---GYISVVD 811
Score = 37.5 bits (83), Expect = 0.13
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 9/143 (6%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ + DMV L+ GA+++ G T LH A +++A L + GAD A G P
Sbjct: 672 EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTP 731
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRD 117
+ +A ++ ++ + K++N L A++ HG
Sbjct: 732 LIVACHYGNVKMVNFLLKQGANVNAKTKNG-YTPLHQAAQQGHTHIINVLLQHGAKPNAT 790
Query: 118 LKTGGTPLHVAAAKGYIDVAKTL 140
G T L +A GYI V TL
Sbjct: 791 TANGNTALAIAKRLGYISVVDTL 813
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 85.8 bits (203), Expect = 4e-16
Identities = 59/192 (30%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V+ L+ H A + G+TPLH +A G + +A LLE+GA + G P+ +A
Sbjct: 511 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA 570
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS---DAREWAL----HGYVEVRDLKTGG 122
D+ + ++ + +N ++ D ++ AL G K G
Sbjct: 571 AKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA K + +A TLL + A+ + V +G TPLH A+ G + LLL GA+ H
Sbjct: 631 TPLHIAAKKNQMQIASTLL-NYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH 689
Query: 183 LKNYSGQTCLDL 194
+ SG T L L
Sbjct: 690 MSTKSGLTSLHL 701
Score = 82.2 bits (194), Expect = 5e-15
Identities = 64/195 (32%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L++V L+ +GA + + G T LH A G + + R LL +GA V A + + P+
Sbjct: 443 HLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 502
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH--------GYVEVRDLK 119
IA +++Q ++ + N +S ARE + G K
Sbjct: 503 IASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGAAHSLATK 561
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G +DVAK LL+ A D G TPLH AA + ++ A LLL+ GA
Sbjct: 562 KGFTPLHVAAKYGSLDVAKLLLQR-RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGA 620
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 621 SPHATAKNGYTPLHI 635
Score = 79.4 bits (187), Expect = 3e-14
Identities = 64/203 (31%), Positives = 94/203 (46%), Gaps = 16/203 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LV GA++N G+TPL+ A I + +YLLE+GA+ + DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163
Query: 63 ELPVDIA----ESDAMADLLQKVIDEKG--------VDCEKSRNAEVDTLMSDAREWALH 110
P+ +A + A+A LL+ D KG + K L+ + +
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN--DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQ 221
Query: 111 GYVEV-RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
+ V R ++G TPLH+AA G ++VA TLL + A D G TPLH A+ G
Sbjct: 222 SKMMVNRTTESGFTPLHIAAHYGNVNVA-TLLLNRGAAVDFTARNGITPLHVASKRGNTN 280
Query: 170 AAALLLKFGADPHLKNYSGQTCL 192
LLL G K G T L
Sbjct: 281 MVKLLLDRGGQIDAKTRDGLTPL 303
Score = 78.6 bits (185), Expect = 6e-14
Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 8/197 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E LV +GA + G TP+H A G ++I LL++GA N G
Sbjct: 405 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 464
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE-----VDTLMSDAREWALHGYVEVRD 117
E + +A ++++ ++ + ++R + L L ++ D
Sbjct: 465 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD 524
Query: 118 LKT--GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
T G TPLH++A +G +DVA LLE A +G+TPLH AA +G + A LLL
Sbjct: 525 AATTNGYTPLHISAREGQVDVASVLLE-AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583
Query: 176 KFGADPHLKNYSGQTCL 192
+ A +G T L
Sbjct: 584 QRRAAADSAGKNGLTPL 600
Score = 77.8 bits (183), Expect = 1e-13
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 10/194 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LL GA+ V G P+
Sbjct: 607 DNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL 666
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRDL 118
+A + D++ ++D KG + S + + +L A+E HG +
Sbjct: 667 HLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHT 725
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G TPL VA G + + LL+ A+ + G+TPLH AA G +LL+ G
Sbjct: 726 KLGYTPLIVACHYGNVKMVNFLLKQ-GANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 784
Query: 179 ADPHLKNYSGQTCL 192
A P+ +G T L
Sbjct: 785 AKPNATTANGNTAL 798
Score = 75.8 bits (178), Expect = 4e-13
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 10/232 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ G ++ +G TPLH A G + LLE GA + A +G P+
Sbjct: 278 NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH 337
Query: 68 IAESDAMADLLQKVIDEKG----VDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDLK 119
+A + ++ ++ K V + V R L R L
Sbjct: 338 MAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN 397
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + L++ A + G TP+H AA G LLL+ GA
Sbjct: 398 -GFTPLHIACKKNRIKVMELLVK-YGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P + N G+T L + + + L+ V+ R+ P H R+
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 507
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 10/181 (5%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
VNR G+TPLH A G +++A LL GA V +G P+ +A ++++ +
Sbjct: 226 VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLL 285
Query: 82 IDEKGVDCEKSRNAEVDTLMSDAR-------EWALH-GYVEVRDLKTGGTPLHVAAAKGY 133
+D G K+R+ + L AR E L G + K G +PLH+AA +
Sbjct: 286 LDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 344
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
++ K LL+ A D V + T LH AA G LLL A+P+ + +G T L
Sbjct: 345 VECVKHLLQH-KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLH 403
Query: 194 L 194
+
Sbjct: 404 I 404
Score = 63.7 bits (148), Expect = 2e-09
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 8/190 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+++ L+ GA V+ G TPLH + G ++ + LL+ G + A DG P+
Sbjct: 245 NVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKTG 121
A +++ +++ +++N M+ + + L V D+
Sbjct: 305 CAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLD 364
Query: 122 G-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
T LHVAA G+ V K LL D A+P+ G+TPLH A + + LL+K+GA
Sbjct: 365 YLTALHVAAHCGHYRVTKLLL-DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGAS 423
Query: 181 PHLKNYSGQT 190
SG T
Sbjct: 424 IQAITESGLT 433
Score = 59.3 bits (137), Expect = 4e-08
Identities = 51/173 (29%), Positives = 81/173 (46%), Gaps = 27/173 (15%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+++ V+ L+ H A V+ + T LH A CG + + LL+ A+ A +G P+
Sbjct: 343 DHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPL 402
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ +G ++G TP+H
Sbjct: 403 HIA-------------------CKKNRIKVMELLVK-------YGASIQAITESGLTPIH 436
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
VAA G++++ LL++ A PD + G T LH AA GQ E LL+ GA
Sbjct: 437 VAAFMGHLNIVLLLLQN-GASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+ + L+ A + G TPLH A +A LLE GA A +G P+
Sbjct: 575 SLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH 634
Query: 68 IA----ESDAMADLLQ-----KVIDEKGVD----CEKSRNAEVDTLMSDAREWALHGYVE 114
IA + + LL ++ ++GV + + ++ TL+ D + +H
Sbjct: 635 IAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD-KGANIH---- 689
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
K+G T LH+AA + ++VA L + AD D G+TPL A +G + L
Sbjct: 690 -MSTKSGLTSLHLAAQEDKVNVADILTKH-GADQDAHTKLGYTPLIVACHYGNVKMVNFL 747
Query: 175 LKFGADPHLKNYSGQTCL 192
LK GA+ + K +G T L
Sbjct: 748 LKQGANVNAKTKNGYTPL 765
Score = 55.6 bits (128), Expect = 5e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 27/169 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
NLD V + G D+N + G LH A G + + + LL G+ V + G +
Sbjct: 43 NLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALH 102
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
IA A+++ KV+ ++G + NA+ + G TPL++
Sbjct: 103 IASLAGQAEVV-KVLVKEGANI----NAQ---------------------SQNGFTPLYM 136
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
AA + +IDV K LLE+ A+ +G+TPL A G +A A+LL+
Sbjct: 137 AAQENHIDVVKYLLEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLE 184
Score = 55.2 bits (127), Expect = 6e-07
Identities = 57/235 (24%), Positives = 100/235 (42%), Gaps = 12/235 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++ +V+ L+ G+ V+ +G T LH + G + + L++ GA++ A + +G
Sbjct: 71 AAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNG 130
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A + D++ K + E G + + L ++ + + T G
Sbjct: 131 FTPLYMAAQENHIDVV-KYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKG 189
Query: 123 ----TPLHVAAAKGYIDVAKTLLE-DCNADPDC------VDYEGWTPLHAAALWGQKEAA 171
LH+AA K A LL+ D NAD G+TPLH AA +G A
Sbjct: 190 KVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVA 249
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
LLL GA +G T L + ++ + + L +++ R P H
Sbjct: 250 TLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N+ MV FL+ GA+VN G+TPLH A G I LL+ GA A +G
Sbjct: 735 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANG 794
Query: 63 ELPVDIAES---DAMADLLQKVIDE 84
+ IA+ ++ D L+ V +E
Sbjct: 795 NTALAIAKRLGYISVVDTLKVVTEE 819
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ + L HGAD + G+TPL G + + +LL+ GA+V A +G
Sbjct: 702 AAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNG 761
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ V+ + G + A +T ++ A+ GY+ V D
Sbjct: 762 YTPLHQAAQQGHTHII-NVLLQHGAK-PNATTANGNTALAIAKRL---GYISVVD 811
Score = 37.5 bits (83), Expect = 0.13
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 9/143 (6%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ + DMV L+ GA+++ G T LH A +++A L + GAD A G P
Sbjct: 672 EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTP 731
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRD 117
+ +A ++ ++ + K++N L A++ HG
Sbjct: 732 LIVACHYGNVKMVNFLLKQGANVNAKTKNG-YTPLHQAAQQGHTHIINVLLQHGAKPNAT 790
Query: 118 LKTGGTPLHVAAAKGYIDVAKTL 140
G T L +A GYI V TL
Sbjct: 791 TANGNTALAIAKRLGYISVVDTL 813
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 85.8 bits (203), Expect = 4e-16
Identities = 59/192 (30%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V+ L+ H A + G+TPLH +A G + +A LLE+GA + G P+ +A
Sbjct: 490 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA 549
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS---DAREWAL----HGYVEVRDLKTGG 122
D+ + ++ + +N ++ D ++ AL G K G
Sbjct: 550 AKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 609
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH+AA K + +A TLL + A+ + V +G TPLH A+ G + LLL GA+ H
Sbjct: 610 TPLHIAAKKNQMQIASTLL-NYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIH 668
Query: 183 LKNYSGQTCLDL 194
+ SG T L L
Sbjct: 669 MSTKSGLTSLHL 680
Score = 82.2 bits (194), Expect = 5e-15
Identities = 64/195 (32%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L++V L+ +GA + + G T LH A G + + R LL +GA V A + + P+
Sbjct: 422 HLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 481
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH--------GYVEVRDLK 119
IA +++Q ++ + N +S ARE + G K
Sbjct: 482 IASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGAAHSLATK 540
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVAA G +DVAK LL+ A D G TPLH AA + ++ A LLL+ GA
Sbjct: 541 KGFTPLHVAAKYGSLDVAKLLLQR-RAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGA 599
Query: 180 DPHLKNYSGQTCLDL 194
PH +G T L +
Sbjct: 600 SPHATAKNGYTPLHI 614
Score = 79.8 bits (188), Expect = 2e-14
Identities = 64/203 (31%), Positives = 94/203 (46%), Gaps = 16/203 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++V+ LV GA++N G+TPL+ A I + +YLLE+GA+ + DG
Sbjct: 83 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 142
Query: 63 ELPVDIA----ESDAMADLLQKVIDEKG--------VDCEKSRNAEVDTLMSDAREWALH 110
P+ +A + A+A LL+ D KG + K L+ + +
Sbjct: 143 FTPLAVALQQGHNQAVAILLEN--DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADIQ 200
Query: 111 GYVEV-RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
+ V R ++G TPLH+AA G ++VA TLL + A D G TPLH A+ G
Sbjct: 201 SKMMVNRTTESGFTPLHIAAHYGNVNVA-TLLLNRGAAVDFTARNGITPLHVASKRGNTN 259
Query: 170 AAALLLKFGADPHLKNYSGQTCL 192
LLL G K G T L
Sbjct: 260 MVKLLLDRGGQIDAKTRDGLTPL 282
Score = 78.6 bits (185), Expect = 6e-14
Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 8/197 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + ++E LV +GA + G TP+H A G ++I LL++GA N G
Sbjct: 384 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 443
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE-----VDTLMSDAREWALHGYVEVRD 117
E + +A ++++ ++ + ++R + L L ++ D
Sbjct: 444 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPD 503
Query: 118 LKT--GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
T G TPLH++A +G +DVA LLE A +G+TPLH AA +G + A LLL
Sbjct: 504 AATTNGYTPLHISAREGQVDVASVLLE-AGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 562
Query: 176 KFGADPHLKNYSGQTCL 192
+ A +G T L
Sbjct: 563 QRRAAADSAGKNGLTPL 579
Score = 77.8 bits (183), Expect = 1e-13
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 10/194 (5%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
DN + L+ GA + G+TPLH A + IA LL GA+ V G P+
Sbjct: 586 DNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL 645
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRDL 118
+A + D++ ++D KG + S + + +L A+E HG +
Sbjct: 646 HLASQEGHTDMVTLLLD-KGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHT 704
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G TPL VA G + + LL+ A+ + G+TPLH AA G +LL+ G
Sbjct: 705 KLGYTPLIVACHYGNVKMVNFLLKQ-GANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHG 763
Query: 179 ADPHLKNYSGQTCL 192
A P+ +G T L
Sbjct: 764 AKPNATTANGNTAL 777
Score = 75.8 bits (178), Expect = 4e-13
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 10/232 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N +MV+ L+ G ++ +G TPLH A G + LLE GA + A +G P+
Sbjct: 257 NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH 316
Query: 68 IAESDAMADLLQKVIDEKG----VDCEKSRNAEVDTLMSDAREWAL----HGYVEVRDLK 119
+A + ++ ++ K V + V R L R L
Sbjct: 317 MAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALN 376
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+A K I V + L++ A + G TP+H AA G LLL+ GA
Sbjct: 377 -GFTPLHIACKKNRIKVMELLVK-YGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 434
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P + N G+T L + + + L+ V+ R+ P H R+
Sbjct: 435 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 486
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/181 (30%), Positives = 85/181 (46%), Gaps = 10/181 (5%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
VNR G+TPLH A G +++A LL GA V +G P+ +A ++++ +
Sbjct: 205 VNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLL 264
Query: 82 IDEKGVDCEKSRNAEVDTLMSDAR-------EWALH-GYVEVRDLKTGGTPLHVAAAKGY 133
+D G K+R+ + L AR E L G + K G +PLH+AA +
Sbjct: 265 LDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 323
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
++ K LL+ A D V + T LH AA G LLL A+P+ + +G T L
Sbjct: 324 VECVKHLLQH-KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLH 382
Query: 194 L 194
+
Sbjct: 383 I 383
Score = 63.7 bits (148), Expect = 2e-09
Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 8/190 (4%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+++ L+ GA V+ G TPLH + G ++ + LL+ G + A DG P+
Sbjct: 224 NVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 283
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKTG 121
A +++ +++ +++N M+ + + L V D+
Sbjct: 284 CAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLD 343
Query: 122 G-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
T LHVAA G+ V K LL D A+P+ G+TPLH A + + LL+K+GA
Sbjct: 344 YLTALHVAAHCGHYRVTKLLL-DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGAS 402
Query: 181 PHLKNYSGQT 190
SG T
Sbjct: 403 IQAITESGLT 412
Score = 59.3 bits (137), Expect = 4e-08
Identities = 51/173 (29%), Positives = 81/173 (46%), Gaps = 27/173 (15%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+++ V+ L+ H A V+ + T LH A CG + + LL+ A+ A +G P+
Sbjct: 322 DHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPL 381
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
IA C+K+R ++ L+ +G ++G TP+H
Sbjct: 382 HIA-------------------CKKNRIKVMELLVK-------YGASIQAITESGLTPIH 415
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
VAA G++++ LL++ A PD + G T LH AA GQ E LL+ GA
Sbjct: 416 VAAFMGHLNIVLLLLQN-GASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 467
Score = 58.8 bits (136), Expect = 5e-08
Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 20/198 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+LD+ + L+ A + G TPLH A +A LLE GA A +G P+
Sbjct: 554 SLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH 613
Query: 68 IA----ESDAMADLLQ-----KVIDEKGVD----CEKSRNAEVDTLMSDAREWALHGYVE 114
IA + + LL ++ ++GV + + ++ TL+ D + +H
Sbjct: 614 IAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLD-KGANIH---- 668
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
K+G T LH+AA + ++VA L + AD D G+TPL A +G + L
Sbjct: 669 -MSTKSGLTSLHLAAQEDKVNVADILTKH-GADQDAHTKLGYTPLIVACHYGNVKMVNFL 726
Query: 175 LKFGADPHLKNYSGQTCL 192
LK GA+ + K +G T L
Sbjct: 727 LKQGANVNAKTKNGYTPL 744
Score = 55.6 bits (128), Expect = 5e-07
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 27/169 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
NLD V + G D+N + G LH A G + + + LL G+ V + G +
Sbjct: 22 NLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALH 81
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
IA A+++ KV+ ++G + NA+ + G TPL++
Sbjct: 82 IASLAGQAEVV-KVLVKEGANI----NAQ---------------------SQNGFTPLYM 115
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
AA + +IDV K LLE+ A+ +G+TPL A G +A A+LL+
Sbjct: 116 AAQENHIDVVKYLLEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLE 163
Score = 54.8 bits (126), Expect = 8e-07
Identities = 57/235 (24%), Positives = 101/235 (42%), Gaps = 12/235 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++ +V+ L+ G+ V+ +G T LH + G + + L++ GA++ A + +G
Sbjct: 50 AAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNG 109
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A + D++ K + E G + + L ++ + + T G
Sbjct: 110 FTPLYMAAQENHIDVV-KYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKG 168
Query: 123 ----TPLHVAAAKGYIDVAKTLLE-DCNAD------PDCVDYEGWTPLHAAALWGQKEAA 171
LH+AA K A LL+ D NAD + G+TPLH AA +G A
Sbjct: 169 KVRLPALHIAARKDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVA 228
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
LLL GA +G T L + ++ + + L +++ R P H
Sbjct: 229 TLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 283
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N+ MV FL+ GA+VN G+TPLH A G I LL+ GA A +G
Sbjct: 714 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANG 773
Query: 63 ELPVDIAES---DAMADLLQKVIDE 84
+ IA+ ++ D L+ V +E
Sbjct: 774 NTALAIAKRLGYISVVDTLKVVTEE 798
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A +D +++ + L HGAD + G+TPL G + + +LL+ GA+V A +G
Sbjct: 681 AAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNG 740
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD 117
P+ A ++ V+ + G + A +T ++ A+ GY+ V D
Sbjct: 741 YTPLHQAAQQGHTHII-NVLLQHGAK-PNATTANGNTALAIAKRL---GYISVVD 790
Score = 37.5 bits (83), Expect = 0.13
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 9/143 (6%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ + DMV L+ GA+++ G T LH A +++A L + GAD A G P
Sbjct: 651 EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTP 710
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WALHGYVEVRD 117
+ +A ++ ++ + K++N L A++ HG
Sbjct: 711 LIVACHYGNVKMVNFLLKQGANVNAKTKNG-YTPLHQAAQQGHTHIINVLLQHGAKPNAT 769
Query: 118 LKTGGTPLHVAAAKGYIDVAKTL 140
G T L +A GYI V TL
Sbjct: 770 TANGNTALAIAKRLGYISVVDTL 792
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/184 (32%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D+VE L +HGADVN D +G L+ A +++A Y LE+GA+V A + +G
Sbjct: 771 AALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEG 830
Query: 63 ELPVDIAESDAMADLLQKVI----DEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEV 115
+ ++ +++Q +I D D EK + + L HG V
Sbjct: 831 RTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 890
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G T L +AA +G+IDV + LLE ADP+ D G T + AA G + LL
Sbjct: 891 HTCNQGATALCIAAQEGHIDVVQVLLEH-GADPNHADQFGRTAMRVAAKNGHSQIIKLLE 949
Query: 176 KFGA 179
K+GA
Sbjct: 950 KYGA 953
Score = 78.2 bits (184), Expect = 8e-14
Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ GADV+ DN G TPL A AS G S+ LL GA V +++ +G
Sbjct: 606 AAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEG 665
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-------ALHGYVEV 115
+ IA + ++++ ++D +G+D +A L A E +
Sbjct: 666 RTVLSIASAQGNVEVVRTLLD-RGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 724
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
++ G P +A+ +G+ D + LLE+ ++ D Y+G L AAL G ++ LL
Sbjct: 725 NEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELL 783
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD + K+ G+ L
Sbjct: 784 FSHGADVNCKDADGRPTL 801
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/185 (35%), Positives = 85/185 (45%), Gaps = 22/185 (11%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+V L+ HGA+VN+ DNEG T L A A G I +LL+ GA+V + DG + +A
Sbjct: 509 DIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVA 568
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
A + +D R AEVD D G TPL VAA
Sbjct: 569 ALCVPASKGHASVVSLLID----RGAEVDHCDKD-----------------GMTPLLVAA 607
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+G++DV LLE AD D D G TPL AAA G LL +GA + G+
Sbjct: 608 YEGHVDVVDLLLEG-GADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR 666
Query: 190 TCLDL 194
T L +
Sbjct: 667 TVLSI 671
Score = 75.4 bits (177), Expect = 5e-13
Identities = 53/185 (28%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A N+++V L+ G D N D+ GWTPLH A G I L+E GA ++ DG
Sbjct: 672 ASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDG 731
Query: 63 ELPVDIAESDAMADLLQKV------IDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR 116
+P +A + D +Q + ID++G D + D E +V
Sbjct: 732 RIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVN 791
Query: 117 DLKTGGTP-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G P L++ A + + +A+ LE+ A+ + D EG T LH + G E +L+
Sbjct: 792 CKDADGRPTLYILALENQLTMAEYFLEN-GANVEASDAEGRTALHVSCWQGHMEMVQVLI 850
Query: 176 KFGAD 180
+ AD
Sbjct: 851 AYHAD 855
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/195 (28%), Positives = 84/195 (43%), Gaps = 14/195 (7%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D + L+ +GA VN+ D+ G T L A G + + L+ GAD+ + G P+ +A
Sbjct: 377 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 436
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG-------- 121
++ +I G + + L S A W H V L G
Sbjct: 437 ARQGHTKVVNCLIG-CGANINHTDQDGWTALRSAA--WGGHTEVVSALLYAGVKVDCADA 493
Query: 122 --GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L AA G+ D+ LL+ A+ + D EG T L AAA G +E LL GA
Sbjct: 494 DSRTALRAAAWGGHEDIVLNLLQH-GAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGA 552
Query: 180 DPHLKNYSGQTCLDL 194
+ + ++ G+T L +
Sbjct: 553 EVNHEDVDGRTALSV 567
Score = 51.2 bits (117), Expect = 1e-05
Identities = 49/199 (24%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++A + +V L+ GA V+ D+EG T L ++ G + + R LL+ G D +
Sbjct: 637 LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD 696
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVE 114
G P+ +A + + + +I++ E + + +++ D + L
Sbjct: 697 AGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSN 756
Query: 115 VRDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G L VAA +G+ D+ + LL AD +C D +G L+ AL Q A
Sbjct: 757 IDQRGYDGRNALRVAALEGHRDIVE-LLFSHGADVNCKDADGRPTLYILALENQLTMAEY 815
Query: 174 LLKFGADPHLKNYSGQTCL 192
L+ GA+ + G+T L
Sbjct: 816 FLENGANVEASDAEGRTAL 834
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
SA ++ +V+ L+ HGA V+ N+G T L A G I + + LLE GAD +
Sbjct: 869 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 928
Query: 62 GELPVDIAESDAMADLLQKVIDEKG 86
G + +A + + ++ K++++ G
Sbjct: 929 GRTAMRVAAKNGHSQII-KLLEKYG 952
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ HGAD N D G T + A G I + L + GA +++N
Sbjct: 903 AAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA--SSLNGCS 960
Query: 63 ELPVDIAESDAMADLLQKV 81
PV E + L KV
Sbjct: 961 PSPVHTMEQKPLQSLSSKV 979
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/184 (32%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D+VE L +HGADVN D +G L+ A +++A Y LE+GA+V A + +G
Sbjct: 234 AALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEG 293
Query: 63 ELPVDIAESDAMADLLQKVI----DEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEV 115
+ ++ +++Q +I D D EK + + L HG V
Sbjct: 294 RTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 353
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G T L +AA +G+IDV + LLE ADP+ D G T + AA G + LL
Sbjct: 354 HTCNQGATALCIAAQEGHIDVVQVLLEH-GADPNHADQFGRTAMRVAAKNGHSQIIKLLE 412
Query: 176 KFGA 179
K+GA
Sbjct: 413 KYGA 416
Score = 78.2 bits (184), Expect = 8e-14
Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ GADV+ DN G TPL A AS G S+ LL GA V +++ +G
Sbjct: 69 AAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEG 128
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-------ALHGYVEV 115
+ IA + ++++ ++D +G+D +A L A E +
Sbjct: 129 RTVLSIASAQGNVEVVRTLLD-RGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 187
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
++ G P +A+ +G+ D + LLE+ ++ D Y+G L AAL G ++ LL
Sbjct: 188 NEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELL 246
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD + K+ G+ L
Sbjct: 247 FSHGADVNCKDADGRPTL 264
Score = 76.2 bits (179), Expect = 3e-13
Identities = 58/183 (31%), Positives = 91/183 (49%), Gaps = 15/183 (8%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASC-----GFISIARYLLESGADVAAVNYDGEL 64
++VE L+ HGA+VN D +G T L A C G S+ L++ GA+V + DG
Sbjct: 5 EIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMT 64
Query: 65 PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD 117
P+ +A + D++ ++ E G D + + N L++ A L V
Sbjct: 65 PLLVAAYEGHVDVVDLLL-EGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDS 123
Query: 118 LKT-GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
+ + G T L +A+A+G ++V +TLL D D + D GWTPLH AA G + L++
Sbjct: 124 IDSEGRTVLSIASAQGNVEVVRTLL-DRGLDENHRDDAGWTPLHMAAFEGHRLICEALIE 182
Query: 177 FGA 179
GA
Sbjct: 183 QGA 185
Score = 75.4 bits (177), Expect = 5e-13
Identities = 53/185 (28%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A N+++V L+ G D N D+ GWTPLH A G I L+E GA ++ DG
Sbjct: 135 ASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDG 194
Query: 63 ELPVDIAESDAMADLLQKV------IDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR 116
+P +A + D +Q + ID++G D + D E +V
Sbjct: 195 RIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVN 254
Query: 117 DLKTGGTP-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G P L++ A + + +A+ LE+ A+ + D EG T LH + G E +L+
Sbjct: 255 CKDADGRPTLYILALENQLTMAEYFLEN-GANVEASDAEGRTALHVSCWQGHMEMVQVLI 313
Query: 176 KFGAD 180
+ AD
Sbjct: 314 AYHAD 318
Score = 51.2 bits (117), Expect = 1e-05
Identities = 49/199 (24%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++A + +V L+ GA V+ D+EG T L ++ G + + R LL+ G D +
Sbjct: 100 LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD 159
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVE 114
G P+ +A + + + +I++ E + + +++ D + L
Sbjct: 160 AGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSN 219
Query: 115 VRDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G L VAA +G+ D+ + LL AD +C D +G L+ AL Q A
Sbjct: 220 IDQRGYDGRNALRVAALEGHRDIVE-LLFSHGADVNCKDADGRPTLYILALENQLTMAEY 278
Query: 174 LLKFGADPHLKNYSGQTCL 192
L+ GA+ + G+T L
Sbjct: 279 FLENGANVEASDAEGRTAL 297
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/76 (43%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
K G TPL VAA +G++DV LLE AD D D G TPL AAA G LL +G
Sbjct: 60 KDGMTPLLVAAYEGHVDVVDLLLEG-GADVDHTDNNGRTPLLAAASMGHASVVNTLLFWG 118
Query: 179 ADPHLKNYSGQTCLDL 194
A + G+T L +
Sbjct: 119 AAVDSIDSEGRTVLSI 134
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
SA ++ +V+ L+ HGA V+ N+G T L A G I + + LLE GAD +
Sbjct: 332 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 391
Query: 62 GELPVDIAESDAMADLLQKVIDEKG 86
G + +A + + ++ K++++ G
Sbjct: 392 GRTAMRVAAKNGHSQII-KLLEKYG 415
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ HGAD N D G T + A G I + L + GA +++N
Sbjct: 366 AAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA--SSLNGCS 423
Query: 63 ELPVDIAESDAMADLLQKV 81
PV E + L KV
Sbjct: 424 PSPVHTMEQKPLQSLSSKV 442
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens cDNA
FLJ45589 fis, clone BRTHA3014547, weakly similar to
Ankyrin 1. ).
Length = 1375
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/184 (32%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D+VE L +HGADVN D +G L+ A +++A Y LE+GA+V A + +G
Sbjct: 866 AALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEG 925
Query: 63 ELPVDIAESDAMADLLQKVI----DEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEV 115
+ ++ +++Q +I D D EK + + L HG V
Sbjct: 926 RTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 985
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G T L +AA +G+IDV + LLE ADP+ D G T + AA G + LL
Sbjct: 986 HTCNQGATALCIAAQEGHIDVVQVLLEH-GADPNHADQFGRTAMRVAAKNGHSQIIKLLE 1044
Query: 176 KFGA 179
K+GA
Sbjct: 1045 KYGA 1048
Score = 78.2 bits (184), Expect = 8e-14
Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ GADV+ DN G TPL A AS G S+ LL GA V +++ +G
Sbjct: 701 AAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEG 760
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-------ALHGYVEV 115
+ IA + ++++ ++D +G+D +A L A E +
Sbjct: 761 RTVLSIASAQGNVEVVRTLLD-RGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 819
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
++ G P +A+ +G+ D + LLE+ ++ D Y+G L AAL G ++ LL
Sbjct: 820 NEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELL 878
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD + K+ G+ L
Sbjct: 879 FSHGADVNCKDADGRPTL 896
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/185 (35%), Positives = 85/185 (45%), Gaps = 22/185 (11%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+V L+ HGA+VN+ DNEG T L A A G I +LL+ GA+V + DG + +A
Sbjct: 604 DIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVA 663
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
A + +D R AEVD D G TPL VAA
Sbjct: 664 ALCVPASKGHASVVSLLID----RGAEVDHCDKD-----------------GMTPLLVAA 702
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+G++DV LLE AD D D G TPL AAA G LL +GA + G+
Sbjct: 703 YEGHVDVVDLLLEG-GADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR 761
Query: 190 TCLDL 194
T L +
Sbjct: 762 TVLSI 766
Score = 75.4 bits (177), Expect = 5e-13
Identities = 53/185 (28%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A N+++V L+ G D N D+ GWTPLH A G I L+E GA ++ DG
Sbjct: 767 ASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDG 826
Query: 63 ELPVDIAESDAMADLLQKV------IDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR 116
+P +A + D +Q + ID++G D + D E +V
Sbjct: 827 RIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVN 886
Query: 117 DLKTGGTP-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G P L++ A + + +A+ LE+ A+ + D EG T LH + G E +L+
Sbjct: 887 CKDADGRPTLYILALENQLTMAEYFLEN-GANVEASDAEGRTALHVSCWQGHMEMVQVLI 945
Query: 176 KFGAD 180
+ AD
Sbjct: 946 AYHAD 950
Score = 55.6 bits (128), Expect = 5e-07
Identities = 55/195 (28%), Positives = 83/195 (42%), Gaps = 14/195 (7%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D + L+ +GA VN+ D+ G T L A G + + L+ GAD+ + G P+ +A
Sbjct: 472 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 531
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG-------- 121
++ +I G + + L S A W H V L G
Sbjct: 532 ARQGHTKVVNCLIG-CGANINHTDQDGWTALRSAA--WGGHTEVVSALLYAGVKVDCADA 588
Query: 122 --GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L AA G D+ LL+ A+ + D EG T L AAA G +E LL GA
Sbjct: 589 DSRTALRAAAWGGREDIVLNLLQH-GAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGA 647
Query: 180 DPHLKNYSGQTCLDL 194
+ + ++ G+T L +
Sbjct: 648 EVNHEDVDGRTALSV 662
Score = 51.2 bits (117), Expect = 1e-05
Identities = 49/199 (24%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++A + +V L+ GA V+ D+EG T L ++ G + + R LL+ G D +
Sbjct: 732 LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD 791
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVE 114
G P+ +A + + + +I++ E + + +++ D + L
Sbjct: 792 AGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSN 851
Query: 115 VRDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G L VAA +G+ D+ + LL AD +C D +G L+ AL Q A
Sbjct: 852 IDQRGYDGRNALRVAALEGHRDIVE-LLFSHGADVNCKDADGRPTLYILALENQLTMAEY 910
Query: 174 LLKFGADPHLKNYSGQTCL 192
L+ GA+ + G+T L
Sbjct: 911 FLENGANVEASDAEGRTAL 929
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
SA ++ +V+ L+ HGA V+ N+G T L A G I + + LLE GAD +
Sbjct: 964 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 1023
Query: 62 GELPVDIAESDAMADLLQKVIDEKG 86
G + +A + + ++ K++++ G
Sbjct: 1024 GRTAMRVAAKNGHSQII-KLLEKYG 1047
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ HGAD N D G T + A G I + L + GA +++N
Sbjct: 998 AAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA--SSLNGCS 1055
Query: 63 ELPVDIAESDAMADLLQKV 81
PV E + L KV
Sbjct: 1056 PSPVHTMEQKPLQSLSSKV 1074
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/184 (32%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ + D+VE L +HGADVN D +G L+ A +++A Y LE+GA+V A + +G
Sbjct: 580 AALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEG 639
Query: 63 ELPVDIAESDAMADLLQKVI----DEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEV 115
+ ++ +++Q +I D D EK + + L HG V
Sbjct: 640 RTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVD 699
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G T L +AA +G+IDV + LLE ADP+ D G T + AA G + LL
Sbjct: 700 HTCNQGATALCIAAQEGHIDVVQVLLEH-GADPNHADQFGRTAMRVAAKNGHSQIIKLLE 758
Query: 176 KFGA 179
K+GA
Sbjct: 759 KYGA 762
Score = 78.2 bits (184), Expect = 8e-14
Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ GADV+ DN G TPL A AS G S+ LL GA V +++ +G
Sbjct: 415 AAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEG 474
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-------ALHGYVEV 115
+ IA + ++++ ++D +G+D +A L A E +
Sbjct: 475 RTVLSIASAQGNVEVVRTLLD-RGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGART 533
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
++ G P +A+ +G+ D + LLE+ ++ D Y+G L AAL G ++ LL
Sbjct: 534 NEIDNDGRIPFILASQEGHYDCVQILLEN-KSNIDQRGYDGRNALRVAALEGHRDIVELL 592
Query: 175 LKFGADPHLKNYSGQTCL 192
GAD + K+ G+ L
Sbjct: 593 FSHGADVNCKDADGRPTL 610
Score = 77.0 bits (181), Expect = 2e-13
Identities = 66/185 (35%), Positives = 85/185 (45%), Gaps = 22/185 (11%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+V L+ HGA+VN+ DNEG T L A A G I +LL+ GA+V + DG + +A
Sbjct: 318 DIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVA 377
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
A + +D R AEVD D G TPL VAA
Sbjct: 378 ALCVPASKGHASVVSLLID----RGAEVDHCDKD-----------------GMTPLLVAA 416
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+G++DV LLE AD D D G TPL AAA G LL +GA + G+
Sbjct: 417 YEGHVDVVDLLLEG-GADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR 475
Query: 190 TCLDL 194
T L +
Sbjct: 476 TVLSI 480
Score = 75.4 bits (177), Expect = 5e-13
Identities = 53/185 (28%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A N+++V L+ G D N D+ GWTPLH A G I L+E GA ++ DG
Sbjct: 481 ASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDG 540
Query: 63 ELPVDIAESDAMADLLQKV------IDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR 116
+P +A + D +Q + ID++G D + D E +V
Sbjct: 541 RIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVN 600
Query: 117 DLKTGGTP-LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
G P L++ A + + +A+ LE+ A+ + D EG T LH + G E +L+
Sbjct: 601 CKDADGRPTLYILALENQLTMAEYFLEN-GANVEASDAEGRTALHVSCWQGHMEMVQVLI 659
Query: 176 KFGAD 180
+ AD
Sbjct: 660 AYHAD 664
Score = 56.8 bits (131), Expect = 2e-07
Identities = 55/195 (28%), Positives = 84/195 (43%), Gaps = 14/195 (7%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D + L+ +GA VN+ D+ G T L A G + + L+ GAD+ + G P+ +A
Sbjct: 186 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 245
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG-------- 121
++ +I G + + L S A W H V L G
Sbjct: 246 ARQGHTKVVNCLIG-CGANINHTDQDGWTALRSAA--WGGHTEVVSALLYAGVKVDCADA 302
Query: 122 --GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L AA G+ D+ LL+ A+ + D EG T L AAA G +E LL GA
Sbjct: 303 DSRTVLRAAAWGGHEDIVLNLLQH-GAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGA 361
Query: 180 DPHLKNYSGQTCLDL 194
+ + ++ G+T L +
Sbjct: 362 EVNHEDVDGRTALSV 376
Score = 51.2 bits (117), Expect = 1e-05
Identities = 49/199 (24%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++A + +V L+ GA V+ D+EG T L ++ G + + R LL+ G D +
Sbjct: 446 LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDD 505
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVE 114
G P+ +A + + + +I++ E + + +++ D + L
Sbjct: 506 AGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSN 565
Query: 115 VRDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G L VAA +G+ D+ + LL AD +C D +G L+ AL Q A
Sbjct: 566 IDQRGYDGRNALRVAALEGHRDIVE-LLFSHGADVNCKDADGRPTLYILALENQLTMAEY 624
Query: 174 LLKFGADPHLKNYSGQTCL 192
L+ GA+ + G+T L
Sbjct: 625 FLENGANVEASDAEGRTAL 643
Score = 42.7 bits (96), Expect = 0.003
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
SA ++ +V+ L+ HGA V+ N+G T L A G I + + LLE GAD +
Sbjct: 678 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 737
Query: 62 GELPVDIAESDAMADLLQKVIDEKG 86
G + +A + + ++ K++++ G
Sbjct: 738 GRTAMRVAAKNGHSQII-KLLEKYG 761
Score = 39.9 bits (89), Expect = 0.025
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + ++D+V+ L+ HGAD N D G T + A G I + L + GA +++N
Sbjct: 712 AAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGA--SSLNGCS 769
Query: 63 ELPVDIAESDAMADLLQKV 81
PV E + L KV
Sbjct: 770 PSPVHTMEQKPLQSLSSKV 788
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 81.4 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +++ ++E L+ GA ++ G TPLH + G + I + LL+ GA N
Sbjct: 378 ACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 437
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
E P+ +A ++ + ++ K K+++ + L AR + L
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQT-PLHCAARIGHTNMVKLLLENNANP 496
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
T G TPLH+AA +G+++ LLE A C+ +G+TPLH AA +G+ A LL
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEK-EASQACMTKKGFTPLHVAAKYGKVRVAELL 555
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P+ +G T L
Sbjct: 556 LERDAHPNAAGKNGLTPL 573
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NLD+V+ L+ G + G+TPLH A + +AR LL+ G A + G P+
Sbjct: 580 NNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 67 DIAESDAMADLLQKVIDEK--GVDCEKSRNAEVDTLMSD-----AREWALHGYVEVRDLK 119
+A + A+++ ++ ++ G KS + + + A HG + +
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTR 699
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVA+ G I + K LL+ AD + G++PLH AA G + LLLK GA
Sbjct: 700 MGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Query: 180 DPHLKNYSGQTCL 192
P+ + G T L
Sbjct: 759 SPNEVSSDGTTPL 771
Score = 75.8 bits (178), Expect = 4e-13
Identities = 67/231 (29%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NL++ + L+ GA VN G TPLH + G + + R LL+ GA + D P+
Sbjct: 217 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKT 120
A + + + ++D K++N M+ D L E+ D+
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL 336
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLHVAA G+ VAK LL D A P+ G+TPLH A LLLK GA
Sbjct: 337 DHLTPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA 395
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
SG T L + + + L+ N + K+ P H R
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 446
Score = 74.9 bits (176), Expect = 7e-13
Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ MV L+ GA + + TPLH A G + I+ LL+ GA + A +G P+
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 310
Query: 68 IAES----DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKT 120
+A D + LLQ + + + V R + G
Sbjct: 311 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K ++ V + LL+ A D V G TPLH A+ G LL+ GA
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKT-GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P++ N +T L + + + + + L+ +VN + P H RI
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 68.1 bits (159), Expect = 8e-11
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 18/200 (9%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+LD V L+ + A+++ + TPLH A CG +A+ LL+ GA + +G P+
Sbjct: 316 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 375
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTGG--- 122
IA +++ ++ + G S +A ++ ++ + G++ V++L G
Sbjct: 376 HIACKKNHVRVMELLL-KTGA----SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 123 --------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH+AA G+ +VAK LL++ A + + TPLH AA G LL
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQN-KAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ A+P+L +G T L +
Sbjct: 490 LENNANPNLATTAGHTPLHI 509
Score = 67.7 bits (158), Expect = 1e-10
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V LV +GA+VN +G+TPL+ A + + ++LLE+GA+ DG P+ +A
Sbjct: 92 EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DL--KTGGTPLH 126
+++ +I+ + + D R A+ + D+ KTG TPLH
Sbjct: 152 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 211
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+AA ++VA+ LL + A + G TPLH A+ G LLL GA K
Sbjct: 212 IAAHYENLNVAQLLL-NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/168 (31%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G+TPLH A G + +A LLE A A +G P+ +A D+++ ++ G
Sbjct: 535 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG- 593
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNAD 147
A +GY TPLH+AA + ++VA++LL+
Sbjct: 594 ---------------SPHSPAWNGY----------TPLHIAAKQNQVEVARSLLQ-YGGS 627
Query: 148 PDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +G TPLH AA G E ALLL A+ +L N SG T L LV
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLV 675
Score = 55.2 bits (127), Expect = 6e-07
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ +V+FL+ H ADVN G++PLH A G I LL++GA V+ DG P+
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 772
Query: 68 IAES---DAMADLLQKVIDE 84
IA+ ++ D+L+ V DE
Sbjct: 773 IAKRLGYISVTDVLKVVTDE 792
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA--------- 53
A +++L++V+FL+ +GA+ N +G+TPL G ++ +L+ G
Sbjct: 118 AAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPAL 177
Query: 54 DVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV 113
+AA N D + ++D D+L K N V L+ + G
Sbjct: 178 HIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN------RGAS 231
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G TPLH+A+ +G + + + LL D A + + TPLH AA G + +
Sbjct: 232 VNFTPQNGITPLHIASRRGNVIMVRLLL-DRGAQIETKTKDELTPLHCAARNGHVRISEI 290
Query: 174 LLKFGADPHLKNYSG 188
LL GA K +G
Sbjct: 291 LLDHGAPIQAKTKNG 305
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 6/171 (3%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G T LH A G + R L+ GA+V A + G P+ +A + +++ K + E G
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV-KFLLENGA 135
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT----PLHVAAAKGYIDVAKTLLED 143
+ + L ++ + + + T G LH+AA A LL++
Sbjct: 136 NQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQN 195
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+ +PD + G+TPLH AA + A LLL GA + +G T L +
Sbjct: 196 -DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + +MV L++ A+ N G+ G TPLH A G + +A L++ G V A G
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG 701
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A L++ ++ + A+V+ K G
Sbjct: 702 YTPLHVASHYGNIKLVKFLLQHQ---------ADVNA-----------------KTKLGY 735
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
+PLH AA +G+ D+ LL++ A P+ V +G TPL A G
Sbjct: 736 SPLHQAAQQGHTDIVTLLLKN-GASPNEVSSDGTTPLAIAKRLG 778
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++ + + L+ HG V+ G+TPLH + G I + ++LL+ ADV A G P
Sbjct: 678 EGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP 737
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ A D++ ++ E S ++ T ++ A+ GY+ V D+
Sbjct: 738 LHQAAQQGHTDIVTLLLKNGASPNEVS--SDGTTPLAIAKRL---GYISVTDV 785
Score = 31.9 bits (69), Expect = 6.5
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A NLD + +G D+N + G LH + G + + LL +
Sbjct: 17 LRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTK 76
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G + IA ++++++++ G + L A+E L V+ L
Sbjct: 77 KGNTALHIAALAGQDEVVRELVN-YGANVNAQSQKGFTPLYMAAQENHLE---VVKFLLE 132
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDC-NADPDCVDY--EG---WTPLHAAALWGQKEAAALL 174
G +VA G+ +A L + N ++Y +G LH AA AA+L
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ +P + + +G T L +
Sbjct: 193 LQNDPNPDVLSKTGFTPLHI 212
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 81.4 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +++ ++E L+ GA ++ G TPLH + G + I + LL+ GA N
Sbjct: 378 ACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 437
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
E P+ +A ++ + ++ K K+++ + L AR + L
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQT-PLHCAARIGHTNMVKLLLENNANP 496
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
T G TPLH+AA +G+++ LLE A C+ +G+TPLH AA +G+ A LL
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEK-EASQACMTKKGFTPLHVAAKYGKVRVAELL 555
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P+ +G T L
Sbjct: 556 LERDAHPNAAGKNGLTPL 573
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NLD+V+ L+ G + G+TPLH A + +AR LL+ G A + G P+
Sbjct: 580 NNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 67 DIAESDAMADLLQKVIDEK--GVDCEKSRNAEVDTLMSD-----AREWALHGYVEVRDLK 119
+A + A+++ ++ ++ G KS + + + A HG + +
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTR 699
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVA+ G I + K LL+ AD + G++PLH AA G + LLLK GA
Sbjct: 700 MGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Query: 180 DPHLKNYSGQTCL 192
P+ + G T L
Sbjct: 759 SPNEVSSDGTTPL 771
Score = 75.8 bits (178), Expect = 4e-13
Identities = 67/231 (29%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NL++ + L+ GA VN G TPLH + G + + R LL+ GA + D P+
Sbjct: 217 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKT 120
A + + + ++D K++N M+ D L E+ D+
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL 336
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLHVAA G+ VAK LL D A P+ G+TPLH A LLLK GA
Sbjct: 337 DHLTPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA 395
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
SG T L + + + L+ N + K+ P H R
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 446
Score = 74.9 bits (176), Expect = 7e-13
Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ MV L+ GA + + TPLH A G + I+ LL+ GA + A +G P+
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 310
Query: 68 IAES----DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKT 120
+A D + LLQ + + + V R + G
Sbjct: 311 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K ++ V + LL+ A D V G TPLH A+ G LL+ GA
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKT-GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P++ N +T L + + + + + L+ +VN + P H RI
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 68.1 bits (159), Expect = 8e-11
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 18/200 (9%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+LD V L+ + A+++ + TPLH A CG +A+ LL+ GA + +G P+
Sbjct: 316 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 375
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTGG--- 122
IA +++ ++ + G S +A ++ ++ + G++ V++L G
Sbjct: 376 HIACKKNHVRVMELLL-KTGA----SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 123 --------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH+AA G+ +VAK LL++ A + + TPLH AA G LL
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQN-KAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ A+P+L +G T L +
Sbjct: 490 LENNANPNLATTAGHTPLHI 509
Score = 67.7 bits (158), Expect = 1e-10
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V LV +GA+VN +G+TPL+ A + + ++LLE+GA+ DG P+ +A
Sbjct: 92 EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DL--KTGGTPLH 126
+++ +I+ + + D R A+ + D+ KTG TPLH
Sbjct: 152 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 211
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+AA ++VA+ LL + A + G TPLH A+ G LLL GA K
Sbjct: 212 IAAHYENLNVAQLLL-NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/168 (31%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G+TPLH A G + +A LLE A A +G P+ +A D+++ ++ G
Sbjct: 535 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG- 593
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNAD 147
A +GY TPLH+AA + ++VA++LL+
Sbjct: 594 ---------------SPHSPAWNGY----------TPLHIAAKQNQVEVARSLLQ-YGGS 627
Query: 148 PDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +G TPLH AA G E ALLL A+ +L N SG T L LV
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLV 675
Score = 55.2 bits (127), Expect = 6e-07
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ +V+FL+ H ADVN G++PLH A G I LL++GA V+ DG P+
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 772
Query: 68 IAES---DAMADLLQKVIDE 84
IA+ ++ D+L+ V DE
Sbjct: 773 IAKRLGYISVTDVLKVVTDE 792
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA--------- 53
A +++L++V+FL+ +GA+ N +G+TPL G ++ +L+ G
Sbjct: 118 AAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPAL 177
Query: 54 DVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV 113
+AA N D + ++D D+L K N V L+ + G
Sbjct: 178 HIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN------RGAS 231
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G TPLH+A+ +G + + + LL D A + + TPLH AA G + +
Sbjct: 232 VNFTPQNGITPLHIASRRGNVIMVRLLL-DRGAQIETKTKDELTPLHCAARNGHVRISEI 290
Query: 174 LLKFGADPHLKNYSG 188
LL GA K +G
Sbjct: 291 LLDHGAPIQAKTKNG 305
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 6/171 (3%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G T LH A G + R L+ GA+V A + G P+ +A + +++ K + E G
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV-KFLLENGA 135
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT----PLHVAAAKGYIDVAKTLLED 143
+ + L ++ + + + T G LH+AA A LL++
Sbjct: 136 NQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQN 195
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+ +PD + G+TPLH AA + A LLL GA + +G T L +
Sbjct: 196 -DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 245
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + +MV L++ A+ N G+ G TPLH A G + +A L++ G V A G
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG 701
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A L++ ++ + A+V+ K G
Sbjct: 702 YTPLHVASHYGNIKLVKFLLQHQ---------ADVNA-----------------KTKLGY 735
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
+PLH AA +G+ D+ LL++ A P+ V +G TPL A G
Sbjct: 736 SPLHQAAQQGHTDIVTLLLKN-GASPNEVSSDGTTPLAIAKRLG 778
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++ + + L+ HG V+ G+TPLH + G I + ++LL+ ADV A G P
Sbjct: 678 EGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP 737
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ A D++ ++ E S ++ T ++ A+ GY+ V D+
Sbjct: 738 LHQAAQQGHTDIVTLLLKNGASPNEVS--SDGTTPLAIAKRL---GYISVTDV 785
Score = 31.9 bits (69), Expect = 6.5
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A NLD + +G D+N + G LH + G + + LL +
Sbjct: 17 LRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTK 76
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G + IA ++++++++ G + L A+E L V+ L
Sbjct: 77 KGNTALHIAALAGQDEVVRELVN-YGANVNAQSQKGFTPLYMAAQENHLE---VVKFLLE 132
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDC-NADPDCVDY--EG---WTPLHAAALWGQKEAAALL 174
G +VA G+ +A L + N ++Y +G LH AA AA+L
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ +P + + +G T L +
Sbjct: 193 LQNDPNPDVLSKTGFTPLHI 212
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 81.4 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +++ ++E L+ GA ++ G TPLH + G + I + LL+ GA N
Sbjct: 345 ACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 404
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
E P+ +A ++ + ++ K K+++ + L AR + L
Sbjct: 405 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQT-PLHCAARIGHTNMVKLLLENNANP 463
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
T G TPLH+AA +G+++ LLE A C+ +G+TPLH AA +G+ A LL
Sbjct: 464 NLATTAGHTPLHIAAREGHVETVLALLEK-EASQACMTKKGFTPLHVAAKYGKVRVAELL 522
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P+ +G T L
Sbjct: 523 LERDAHPNAAGKNGLTPL 540
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NLD+V+ L+ G + G+TPLH A + +AR LL+ G A + G P+
Sbjct: 547 NNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 606
Query: 67 DIAESDAMADLLQKVIDEK--GVDCEKSRNAEVDTLMSD-----AREWALHGYVEVRDLK 119
+A + A+++ ++ ++ G KS + + + A HG + +
Sbjct: 607 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTR 666
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVA+ G I + K LL+ AD + G++PLH AA G + LLLK GA
Sbjct: 667 MGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 725
Query: 180 DPHLKNYSGQTCL 192
P+ + G T L
Sbjct: 726 SPNEVSSDGTTPL 738
Score = 75.8 bits (178), Expect = 4e-13
Identities = 67/231 (29%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NL++ + L+ GA VN G TPLH + G + + R LL+ GA + D P+
Sbjct: 184 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 243
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKT 120
A + + + ++D K++N M+ D L E+ D+
Sbjct: 244 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL 303
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLHVAA G+ VAK LL D A P+ G+TPLH A LLLK GA
Sbjct: 304 DHLTPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA 362
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
SG T L + + + L+ N + K+ P H R
Sbjct: 363 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 413
Score = 74.9 bits (176), Expect = 7e-13
Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ MV L+ GA + + TPLH A G + I+ LL+ GA + A +G P+
Sbjct: 218 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 277
Query: 68 IAES----DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKT 120
+A D + LLQ + + + V R + G
Sbjct: 278 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 337
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K ++ V + LL+ A D V G TPLH A+ G LL+ GA
Sbjct: 338 GFTPLHIACKKNHVRVMELLLKT-GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 396
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P++ N +T L + + + + + L+ +VN + P H RI
Sbjct: 397 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI 447
Score = 68.1 bits (159), Expect = 8e-11
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 18/200 (9%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+LD V L+ + A+++ + TPLH A CG +A+ LL+ GA + +G P+
Sbjct: 283 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 342
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTGG--- 122
IA +++ ++ + G S +A ++ ++ + G++ V++L G
Sbjct: 343 HIACKKNHVRVMELLL-KTGA----SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 397
Query: 123 --------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH+AA G+ +VAK LL++ A + + TPLH AA G LL
Sbjct: 398 NVSNVKVETPLHMAARAGHTEVAKYLLQN-KAKVNAKAKDDQTPLHCAARIGHTNMVKLL 456
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ A+P+L +G T L +
Sbjct: 457 LENNANPNLATTAGHTPLHI 476
Score = 67.7 bits (158), Expect = 1e-10
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V LV +GA+VN +G+TPL+ A + + ++LLE+GA+ DG P+ +A
Sbjct: 59 EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 118
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DL--KTGGTPLH 126
+++ +I+ + + D R A+ + D+ KTG TPLH
Sbjct: 119 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 178
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+AA ++VA+ LL + A + G TPLH A+ G LLL GA K
Sbjct: 179 IAAHYENLNVAQLLL-NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 235
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/168 (31%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G+TPLH A G + +A LLE A A +G P+ +A D+++ ++ G
Sbjct: 502 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG- 560
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNAD 147
A +GY TPLH+AA + ++VA++LL+
Sbjct: 561 ---------------SPHSPAWNGY----------TPLHIAAKQNQVEVARSLLQ-YGGS 594
Query: 148 PDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +G TPLH AA G E ALLL A+ +L N SG T L LV
Sbjct: 595 ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLV 642
Score = 60.1 bits (139), Expect = 2e-08
Identities = 53/198 (26%), Positives = 88/198 (44%), Gaps = 6/198 (3%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A NLD + +G D+N + +G T LH A G + R L+ GA+V A +
Sbjct: 17 LRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQ 76
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G P+ +A + +++ K + E G + + L ++ + + + T
Sbjct: 77 KGFTPLYMAAQENHLEVV-KFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGT 135
Query: 121 GG----TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
G LH+AA A LL++ + +PD + G+TPLH AA + A LLL
Sbjct: 136 KGKVRLPALHIAARNDDTRTAAVLLQN-DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 194
Query: 177 FGADPHLKNYSGQTCLDL 194
GA + +G T L +
Sbjct: 195 RGASVNFTPQNGITPLHI 212
Score = 55.2 bits (127), Expect = 6e-07
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ +V+FL+ H ADVN G++PLH A G I LL++GA V+ DG P+
Sbjct: 680 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 739
Query: 68 IAES---DAMADLLQKVIDE 84
IA+ ++ D+L+ V DE
Sbjct: 740 IAKRLGYISVTDVLKVVTDE 759
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + +MV L++ A+ N G+ G TPLH A G + +A L++ G V A G
Sbjct: 609 AAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG 668
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A L++ ++ + A+V+ K G
Sbjct: 669 YTPLHVASHYGNIKLVKFLLQHQ---------ADVNA-----------------KTKLGY 702
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
+PLH AA +G+ D+ LL++ A P+ V +G TPL A G
Sbjct: 703 SPLHQAAQQGHTDIVTLLLKN-GASPNEVSSDGTTPLAIAKRLG 745
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++ + + L+ HG V+ G+TPLH + G I + ++LL+ ADV A G P
Sbjct: 645 EGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP 704
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ A D++ ++ E S ++ T ++ A+ GY+ V D+
Sbjct: 705 LHQAAQQGHTDIVTLLLKNGASPNEVS--SDGTTPLAIAKRL---GYISVTDV 752
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 81.4 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +++ ++E L+ GA ++ G TPLH + G + I + LL+ GA N
Sbjct: 378 ACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 437
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
E P+ +A ++ + ++ K K+++ + L AR + L
Sbjct: 438 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQT-PLHCAARIGHTNMVKLLLENNANP 496
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
T G TPLH+AA +G+++ LLE A C+ +G+TPLH AA +G+ A LL
Sbjct: 497 NLATTAGHTPLHIAAREGHVETVLALLEK-EASQACMTKKGFTPLHVAAKYGKVRVAELL 555
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P+ +G T L
Sbjct: 556 LERDAHPNAAGKNGLTPL 573
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NLD+V+ L+ G + G+TPLH A + +AR LL+ G A + G P+
Sbjct: 580 NNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 67 DIAESDAMADLLQKVIDEK--GVDCEKSRNAEVDTLMSD-----AREWALHGYVEVRDLK 119
+A + A+++ ++ ++ G KS + + + A HG + +
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTR 699
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVA+ G I + K LL+ AD + G++PLH AA G + LLLK GA
Sbjct: 700 MGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Query: 180 DPHLKNYSGQTCL 192
P+ + G T L
Sbjct: 759 SPNEVSSDGTTPL 771
Score = 74.9 bits (176), Expect = 7e-13
Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ MV L+ GA + + TPLH A G + I+ LL+ GA + A +G P+
Sbjct: 251 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 310
Query: 68 IAES----DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKT 120
+A D + LLQ + + + V R + G
Sbjct: 311 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K ++ V + LL+ A D V G TPLH A+ G LL+ GA
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKT-GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 429
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P++ N +T L + + + + + L+ +VN + P H RI
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 74.5 bits (175), Expect = 9e-13
Identities = 66/231 (28%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NL++ + L+ G+ VN G TPLH + G + + R LL+ GA + D P+
Sbjct: 217 ENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKT 120
A + + + ++D K++N M+ D L E+ D+
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL 336
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLHVAA G+ VAK LL D A P+ G+TPLH A LLLK GA
Sbjct: 337 DHLTPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA 395
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
SG T L + + + L+ N + K+ P H R
Sbjct: 396 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 446
Score = 68.1 bits (159), Expect = 8e-11
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 18/200 (9%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+LD V L+ + A+++ + TPLH A CG +A+ LL+ GA + +G P+
Sbjct: 316 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 375
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTGG--- 122
IA +++ ++ + G S +A ++ ++ + G++ V++L G
Sbjct: 376 HIACKKNHVRVMELLL-KTGA----SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 123 --------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH+AA G+ +VAK LL++ A + + TPLH AA G LL
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQN-KAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ A+P+L +G T L +
Sbjct: 490 LENNANPNLATTAGHTPLHI 509
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V LV +GA+VN +G+TPL+ A + + ++LLE+GA+ DG P+ +A
Sbjct: 92 EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 151
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DL--KTGGTPLH 126
+++ +I+ + + D R A+ + D+ KTG TPLH
Sbjct: 152 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 211
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+AA ++VA+ LL + + + G TPLH A+ G LLL GA K
Sbjct: 212 IAAHYENLNVAQLLL-NRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/168 (31%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G+TPLH A G + +A LLE A A +G P+ +A D+++ ++ G
Sbjct: 535 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG- 593
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNAD 147
A +GY TPLH+AA + ++VA++LL+
Sbjct: 594 ---------------SPHSPAWNGY----------TPLHIAAKQNQVEVARSLLQ-YGGS 627
Query: 148 PDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +G TPLH AA G E ALLL A+ +L N SG T L LV
Sbjct: 628 ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLV 675
Score = 55.2 bits (127), Expect = 6e-07
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ +V+FL+ H ADVN G++PLH A G I LL++GA V+ DG P+
Sbjct: 713 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 772
Query: 68 IAES---DAMADLLQKVIDE 84
IA+ ++ D+L+ V DE
Sbjct: 773 IAKRLGYISVTDVLKVVTDE 792
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA--------- 53
A +++L++V+FL+ +GA+ N +G+TPL G ++ +L+ G
Sbjct: 118 AAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPAL 177
Query: 54 DVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV 113
+AA N D + ++D D+L K N V L+ + G
Sbjct: 178 HIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN------RGSS 231
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G TPLH+A+ +G + + + LL D A + + TPLH AA G + +
Sbjct: 232 VNFTPQNGITPLHIASRRGNVIMVRLLL-DRGAQIETKTKDELTPLHCAARNGHVRISEI 290
Query: 174 LLKFGADPHLKNYSG 188
LL GA K +G
Sbjct: 291 LLDHGAPIQAKTKNG 305
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + +MV L++ A+ N G+ G TPLH A G + +A L++ G V A G
Sbjct: 642 AAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG 701
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A L++ ++ + A+V+ K G
Sbjct: 702 YTPLHVASHYGNIKLVKFLLQHQ---------ADVNA-----------------KTKLGY 735
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
+PLH AA +G+ D+ LL++ A P+ V +G TPL A G
Sbjct: 736 SPLHQAAQQGHTDIVTLLLKN-GASPNEVSSDGTTPLAIAKRLG 778
Score = 48.4 bits (110), Expect = 7e-05
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 6/171 (3%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G T LH A G + R L+ GA+V A + G P+ +A + +++ K + E G
Sbjct: 77 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV-KFLLENGA 135
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT----PLHVAAAKGYIDVAKTLLED 143
+ + L ++ + + + T G LH+AA A LL++
Sbjct: 136 NQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQN 195
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+ +PD + G+TPLH AA + A LLL G+ + +G T L +
Sbjct: 196 -DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHI 245
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++ + + L+ HG V+ G+TPLH + G I + ++LL+ ADV A G P
Sbjct: 678 EGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP 737
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ A D++ ++ E S ++ T ++ A+ GY+ V D+
Sbjct: 738 LHQAAQQGHTDIVTLLLKNGASPNEVS--SDGTTPLAIAKRL---GYISVTDV 785
Score = 31.9 bits (69), Expect = 6.5
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A NLD + +G D+N + G LH + G + + LL +
Sbjct: 17 LRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTK 76
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G + IA ++++++++ G + L A+E L V+ L
Sbjct: 77 KGNTALHIAALAGQDEVVRELVN-YGANVNAQSQKGFTPLYMAAQENHLE---VVKFLLE 132
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDC-NADPDCVDY--EG---WTPLHAAALWGQKEAAALL 174
G +VA G+ +A L + N ++Y +G LH AA AA+L
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 192
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ +P + + +G T L +
Sbjct: 193 LQNDPNPDVLSKTGFTPLHI 212
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 81.4 bits (192), Expect = 8e-15
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 10/198 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +++ ++E L+ GA ++ G TPLH + G + I + LL+ GA N
Sbjct: 413 ACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 472
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
E P+ +A ++ + ++ K K+++ + L AR + L
Sbjct: 473 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQT-PLHCAARIGHTNMVKLLLENNANP 531
Query: 116 RDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
T G TPLH+AA +G+++ LLE A C+ +G+TPLH AA +G+ A LL
Sbjct: 532 NLATTAGHTPLHIAAREGHVETVLALLEK-EASQACMTKKGFTPLHVAAKYGKVRVAELL 590
Query: 175 LKFGADPHLKNYSGQTCL 192
L+ A P+ +G T L
Sbjct: 591 LERDAHPNAAGKNGLTPL 608
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NLD+V+ L+ G + G+TPLH A + +AR LL+ G A + G P+
Sbjct: 615 NNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 674
Query: 67 DIAESDAMADLLQKVIDEK--GVDCEKSRNAEVDTLMSD-----AREWALHGYVEVRDLK 119
+A + A+++ ++ ++ G KS + + + A HG + +
Sbjct: 675 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTR 734
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLHVA+ G I + K LL+ AD + G++PLH AA G + LLLK GA
Sbjct: 735 MGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 793
Query: 180 DPHLKNYSGQTCL 192
P+ + G T L
Sbjct: 794 SPNEVSSDGTTPL 806
Score = 75.8 bits (178), Expect = 4e-13
Identities = 67/231 (29%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+NL++ + L+ GA VN G TPLH + G + + R LL+ GA + D P+
Sbjct: 252 ENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 311
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMS------DAREWALHGYVEVRDLKT 120
A + + + ++D K++N M+ D L E+ D+
Sbjct: 312 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITL 371
Query: 121 GG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPLHVAA G+ VAK LL D A P+ G+TPLH A LLLK GA
Sbjct: 372 DHLTPLHVAAHCGHHRVAKVLL-DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA 430
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
SG T L + + + L+ N + K+ P H R
Sbjct: 431 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 481
Score = 74.9 bits (176), Expect = 7e-13
Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 8/231 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ MV L+ GA + + TPLH A G + I+ LL+ GA + A +G P+
Sbjct: 286 NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIH 345
Query: 68 IAES----DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL---HGYVEVRDLKT 120
+A D + LLQ + + + V R + G
Sbjct: 346 MAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 405
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A K ++ V + LL+ A D V G TPLH A+ G LL+ GA
Sbjct: 406 GFTPLHIACKKNHVRVMELLLKT-GASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGAS 464
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKRI 231
P++ N +T L + + + + + L+ +VN + P H RI
Sbjct: 465 PNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARI 515
Score = 68.1 bits (159), Expect = 8e-11
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 18/200 (9%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
D+LD V L+ + A+++ + TPLH A CG +A+ LL+ GA + +G P+
Sbjct: 351 DHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPL 410
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLKTGG--- 122
IA +++ ++ + G S +A ++ ++ + G++ V++L G
Sbjct: 411 HIACKKNHVRVMELLL-KTGA----SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 465
Query: 123 --------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TPLH+AA G+ +VAK LL++ A + + TPLH AA G LL
Sbjct: 466 NVSNVKVETPLHMAARAGHTEVAKYLLQN-KAKVNAKAKDDQTPLHCAARIGHTNMVKLL 524
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ A+P+L +G T L +
Sbjct: 525 LENNANPNLATTAGHTPLHI 544
Score = 67.7 bits (158), Expect = 1e-10
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++V LV +GA+VN +G+TPL+ A + + ++LLE+GA+ DG P+ +A
Sbjct: 127 EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVA 186
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVR-DL--KTGGTPLH 126
+++ +I+ + + D R A+ + D+ KTG TPLH
Sbjct: 187 LQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH 246
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+AA ++VA+ LL + A + G TPLH A+ G LLL GA K
Sbjct: 247 IAAHYENLNVAQLLL-NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 303
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/168 (31%), Positives = 77/168 (45%), Gaps = 27/168 (16%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G+TPLH A G + +A LLE A A +G P+ +A D+++ ++ G
Sbjct: 570 KGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGG- 628
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNAD 147
A +GY TPLH+AA + ++VA++LL+
Sbjct: 629 ---------------SPHSPAWNGY----------TPLHIAAKQNQVEVARSLLQ-YGGS 662
Query: 148 PDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +G TPLH AA G E ALLL A+ +L N SG T L LV
Sbjct: 663 ANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLV 710
Score = 55.2 bits (127), Expect = 6e-07
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
N+ +V+FL+ H ADVN G++PLH A G I LL++GA V+ DG P+
Sbjct: 748 NIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLA 807
Query: 68 IAES---DAMADLLQKVIDE 84
IA+ ++ D+L+ V DE
Sbjct: 808 IAKRLGYISVTDVLKVVTDE 827
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA--------- 53
A +++L++V+FL+ +GA+ N +G+TPL G ++ +L+ G
Sbjct: 153 AAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPAL 212
Query: 54 DVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYV 113
+AA N D + ++D D+L K N V L+ + G
Sbjct: 213 HIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN------RGAS 266
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ G TPLH+A+ +G + + + LL D A + + TPLH AA G + +
Sbjct: 267 VNFTPQNGITPLHIASRRGNVIMVRLLL-DRGAQIETKTKDELTPLHCAARNGHVRISEI 325
Query: 174 LLKFGADPHLKNYSG 188
LL GA K +G
Sbjct: 326 LLDHGAPIQAKTKNG 340
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 6/171 (3%)
Query: 28 EGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGV 87
+G T LH A G + R L+ GA+V A + G P+ +A + +++ K + E G
Sbjct: 112 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV-KFLLENGA 170
Query: 88 DCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT----PLHVAAAKGYIDVAKTLLED 143
+ + L ++ + + + T G LH+AA A LL++
Sbjct: 171 NQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQN 230
Query: 144 CNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
+ +PD + G+TPLH AA + A LLL GA + +G T L +
Sbjct: 231 -DPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHI 280
Score = 48.8 bits (111), Expect = 5e-05
Identities = 45/164 (27%), Positives = 73/164 (44%), Gaps = 27/164 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + +MV L++ A+ N G+ G TPLH A G + +A L++ G V A G
Sbjct: 677 AAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG 736
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ +A L++ ++ + A+V+ K G
Sbjct: 737 YTPLHVASHYGNIKLVKFLLQHQ---------ADVNA-----------------KTKLGY 770
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
+PLH AA +G+ D+ LL++ A P+ V +G TPL A G
Sbjct: 771 SPLHQAAQQGHTDIVTLLLKN-GASPNEVSSDGTTPLAIAKRLG 813
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 6 DDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELP 65
+ ++ + + L+ HG V+ G+TPLH + G I + ++LL+ ADV A G P
Sbjct: 713 EGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP 772
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
+ A D++ ++ E S ++ T ++ A+ GY+ V D+
Sbjct: 773 LHQAAQQGHTDIVTLLLKNGASPNEVS--SDGTTPLAIAKRL---GYISVTDV 820
Score = 31.9 bits (69), Expect = 6.5
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 10/200 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ A NLD + +G D+N + G LH + G + + LL +
Sbjct: 52 LRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTK 111
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
G + IA ++++++++ G + L A+E L V+ L
Sbjct: 112 KGNTALHIAALAGQDEVVRELVN-YGANVNAQSQKGFTPLYMAAQENHLE---VVKFLLE 167
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDC-NADPDCVDY--EG---WTPLHAAALWGQKEAAALL 174
G +VA G+ +A L + N ++Y +G LH AA AA+L
Sbjct: 168 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVL 227
Query: 175 LKFGADPHLKNYSGQTCLDL 194
L+ +P + + +G T L +
Sbjct: 228 LQNDPNPDVLSKTGFTPLHI 247
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 459 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 518
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 519 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 576
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 577 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 635
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 636 VEALTTDGKTAEDL 649
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 414 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 447
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 448 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 506
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 507 KNREGETPL 515
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 584 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 643
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 644 KTAEDLARSE 653
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 459 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 518
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 519 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 576
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 577 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 635
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 636 VEALTTDGKTAEDL 649
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 414 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 447
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 448 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 506
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 507 KNREGETPL 515
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 584 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 643
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 644 KTAEDLARSE 653
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 77.0 bits (181), Expect = 2e-13
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 534 VVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVAC 593
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 594 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 650
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 651 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 709
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 710 GKEAMTSDGYTALHL 724
Score = 55.2 bits (127), Expect = 6e-07
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 592 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 651
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 652 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 685
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A + + +G+T LH AA G LL++ AD
Sbjct: 686 QTPLHVAAETGHTSTARLLLHR-GAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADV 744
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 745 LARGPLNQTALHL 757
Score = 50.8 bits (116), Expect = 1e-05
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
Query: 8 NLDMVEFLVTH-GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+L +V+ L G VN +G TPLH A G +AR L++ +DV + + P+
Sbjct: 630 HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPL 689
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHG----YVEVRDLKTGG 122
+A + ++ +G E + L AR L E D+ G
Sbjct: 690 HVAAETGHTSTARLLL-HRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 748
Query: 123 ----TPLHVAAAKGYIDVAKTLLEDCNADP-DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH+AAA G+ +V + L+ +AD D D +G + LH AA + LL+
Sbjct: 749 PLNQTALHLAAAHGHSEVVEELV---SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRH 805
Query: 178 GADPHLKNYSGQ 189
GA +L++ Q
Sbjct: 806 GAHINLQSLKFQ 817
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 27/164 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + +++
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
++ K S NA+ D +W T LH AA G + L
Sbjct: 538 LLARK-----ISVNAK------DEDQW---------------TALHFAAQNGDESSTRLL 571
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LE NA + VD+EG TP+H A GQ+ +LL+ G D L+
Sbjct: 572 LEK-NASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ 614
Score = 41.5 bits (93), Expect = 0.008
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 428 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 486
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 487 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLAR-KISV 545
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G+T
Sbjct: 546 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 587
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 459 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 518
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 519 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 576
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 577 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 635
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 636 VEALTTDGKTAEDL 649
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 414 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 447
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 448 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 506
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 507 KNREGETPL 515
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 584 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 643
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 644 KTAEDLARSE 653
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 459 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 518
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 519 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 576
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 577 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 635
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 636 VEALTTDGKTAEDL 649
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 414 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 447
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 448 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 506
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 507 KNREGETPL 515
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 584 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 643
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 644 KTAEDLARSE 653
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 459 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 518
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 519 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 576
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 577 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 635
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 636 VEALTTDGKTAEDL 649
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 414 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 447
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 448 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 506
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 507 KNREGETPL 515
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 584 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 643
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 644 KTAEDLARSE 653
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/194 (30%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G+ S+A+ L E+G +V N +GE P+ A
Sbjct: 462 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTA 521
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 522 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 579
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 580 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 638
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 639 VEALTTDGKTAEDL 652
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 29/189 (15%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 357 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 416
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGT 123
V A D L+ + + K C ++V+D K+G
Sbjct: 417 NAVYWAARHGHVDTLKFLSENK---CP----------------------LDVKD-KSGEM 450
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++
Sbjct: 451 ALHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNI 509
Query: 184 KNYSGQTCL 192
KN G+T L
Sbjct: 510 KNREGETPL 518
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 587 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 646
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 647 KTAEDLARSE 656
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 76.6 bits (180), Expect = 2e-13
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 486 VVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVAC 545
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 546 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 602
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 662 GKEAVTSDGYTALHL 676
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/193 (29%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 544 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 603
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 604 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 637
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A + V +G+T LH AA G LL++ AD
Sbjct: 638 QTPLHVAAETGHTSTARLLLHR-GAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV 696
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 697 LARGPLNQTALHL 709
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
Query: 8 NLDMVEFLVTH-GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+L +V+ L G VN +G TPLH A G +AR L++ +DV + + P+
Sbjct: 582 HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPL 641
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHG----YVEVRDLKTGG 122
+A + ++ +G E + L AR L E D+ G
Sbjct: 642 HVAAETGHTSTARLLL-HRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 700
Query: 123 ----TPLHVAAAKGYIDVAKTLLEDCNADP-DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH+AAA G+ +V + L+ +AD D D +G + LH AA + LL+
Sbjct: 701 PLNQTALHLAAAHGHSEVVEELV---SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRH 757
Query: 178 GADPHLKNYSGQ 189
GA +L++ Q
Sbjct: 758 GAHINLQSLKFQ 769
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 27/164 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + +++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
++ K S NA+ D +W T LH AA G + L
Sbjct: 490 LLARK-----ISVNAK------DEDQW---------------TALHFAAQNGDESSTRLL 523
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LE NA + VD+EG TP+H A GQ+ +LL+ G D L+
Sbjct: 524 LEK-NASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ 566
Score = 41.5 bits (93), Expect = 0.008
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 380 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 438
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 439 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLAR-KISV 497
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G+T
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 76.6 bits (180), Expect = 2e-13
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 486 VVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVAC 545
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 546 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 602
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 662 GKEAVTSDGYTALHL 676
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/193 (29%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 544 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 603
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 604 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 637
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A + V +G+T LH AA G LL++ AD
Sbjct: 638 QTPLHVAAETGHTSTARLLLHR-GAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV 696
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 697 LARGPLNQTALHL 709
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
Query: 8 NLDMVEFLVTH-GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+L +V+ L G VN +G TPLH A G +AR L++ +DV + + P+
Sbjct: 582 HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPL 641
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHG----YVEVRDLKTGG 122
+A + ++ +G E + L AR L E D+ G
Sbjct: 642 HVAAETGHTSTARLLL-HRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 700
Query: 123 ----TPLHVAAAKGYIDVAKTLLEDCNADP-DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH+AAA G+ +V + L+ +AD D D +G + LH AA + LL+
Sbjct: 701 PLNQTALHLAAAHGHSEVVEELV---SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRH 757
Query: 178 GADPHLKNYSGQ 189
GA +L++ Q
Sbjct: 758 GAHINLQSLKFQ 769
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 27/164 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + +++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
++ K S NA+ D +W T LH AA G + L
Sbjct: 490 LLARK-----ISVNAK------DEDQW---------------TALHFAAQNGDESSTRLL 523
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LE NA + VD+EG TP+H A GQ+ +LL+ G D L+
Sbjct: 524 LEK-NASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ 566
Score = 41.5 bits (93), Expect = 0.008
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 380 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 438
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 439 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLAR-KISV 497
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G+T
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 76.6 bits (180), Expect = 2e-13
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 486 VVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVAC 545
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 546 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 602
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 662 GKEAVTSDGYTALHL 676
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/193 (29%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 544 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 603
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 604 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 637
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A + V +G+T LH AA G LL++ AD
Sbjct: 638 QTPLHVAAETGHTSTARLLLHR-GAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV 696
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 697 LARGPLNQTALHL 709
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
Query: 8 NLDMVEFLVTH-GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+L +V+ L G VN +G TPLH A G +AR L++ +DV + + P+
Sbjct: 582 HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPL 641
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHG----YVEVRDLKTGG 122
+A + ++ +G E + L AR L E D+ G
Sbjct: 642 HVAAETGHTSTARLLL-HRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 700
Query: 123 ----TPLHVAAAKGYIDVAKTLLEDCNADP-DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH+AAA G+ +V + L+ +AD D D +G + LH AA + LL+
Sbjct: 701 PLNQTALHLAAAHGHSEVVEELV---SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRH 757
Query: 178 GADPHLKNYSGQ 189
GA +L++ Q
Sbjct: 758 GAHINLQSLKFQ 769
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 27/164 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + +++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
++ K S NA+ D +W T LH AA G + L
Sbjct: 490 LLARK-----ISVNAK------DEDQW---------------TALHFAAQNGDESSTRLL 523
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LE NA + VD+EG TP+H A GQ+ +LL+ G D L+
Sbjct: 524 LEK-NASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ 566
Score = 41.5 bits (93), Expect = 0.008
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 380 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 438
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 439 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLAR-KISV 497
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G+T
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
>BC112094-1|AAI12095.1| 154|Homo sapiens dysferlin interacting
protein 1 (toonin) protein.
Length = 154
Score = 76.2 bits (179), Expect = 3e-13
Identities = 34/70 (48%), Positives = 46/70 (65%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + NL+ V+ LV +GAD+++ D GWTPLH S G+ IARYL+ GAD A N DG
Sbjct: 71 AVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
Query: 63 ELPVDIAESD 72
+LP D+ + D
Sbjct: 131 DLPSDLIDPD 140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
+G LH A G ++ K L++ AD D GWTPLH A G + A L+ GA
Sbjct: 63 SGLAALHEAVLSGNLECVKLLVK-YGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLE 204
D N G DL+DP +E
Sbjct: 122 DRDATNDDGDLPSDLIDPDYKELVE 146
Score = 34.7 bits (76), Expect = 0.93
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTP 158
+ RD + G TPLH+A + GY D+A+ L+ AD D + +G P
Sbjct: 90 IHQRD-EAGWTPLHIACSDGYPDIARYLI-SLGADRDATNDDGDLP 133
>BC093707-1|AAH93707.1| 154|Homo sapiens dysferlin interacting
protein 1 (toonin) protein.
Length = 154
Score = 76.2 bits (179), Expect = 3e-13
Identities = 34/70 (48%), Positives = 46/70 (65%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + NL+ V+ LV +GAD+++ D GWTPLH S G+ IARYL+ GAD A N DG
Sbjct: 71 AVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
Query: 63 ELPVDIAESD 72
+LP D+ + D
Sbjct: 131 DLPSDLIDPD 140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
+G LH A G ++ K L++ AD D GWTPLH A G + A L+ GA
Sbjct: 63 SGLAALHEAVLSGNLECVKLLVK-YGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLE 204
D N G DL+DP +E
Sbjct: 122 DRDATNDDGDLPSDLIDPDYKELVE 146
Score = 34.7 bits (76), Expect = 0.93
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTP 158
+ RD + G TPLH+A + GY D+A+ L+ AD D + +G P
Sbjct: 90 IHQRD-EAGWTPLHIACSDGYPDIARYLI-SLGADRDATNDDGDLP 133
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 486 VVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVAC 545
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 546 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 602
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 662 GKKAVTSDGYTALHL 676
Score = 55.2 bits (127), Expect = 6e-07
Identities = 56/193 (29%), Positives = 77/193 (39%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 544 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 603
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 604 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 637
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A V +G+T LH AA G LL++ AD
Sbjct: 638 QTPLHVAAETGHTSTARLLLHR-GAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADV 696
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 697 LARGPLNQTALHL 709
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/164 (28%), Positives = 71/164 (43%), Gaps = 27/164 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + +++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
++ K S NA+ D +W T LH AA G + L
Sbjct: 490 LLARK-----ISVNAK------DEDQW---------------TALHFAAQNGDESSTRLL 523
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LE NA + VD+EG TP+H A GQ+ +LL+ G D L+
Sbjct: 524 LEK-NASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ 566
Score = 41.5 bits (93), Expect = 0.008
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 380 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 438
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 439 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLAR-KISV 497
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G+T
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/74 (22%), Positives = 38/74 (51%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L+ GA ++G+T LH A G ++ + L+E ADV A + + +A +
Sbjct: 656 LLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGH 715
Query: 75 ADLLQKVIDEKGVD 88
++++++++ +D
Sbjct: 716 SEVVEELVSADVID 729
>AF434846-1|AAO67357.1| 154|Homo sapiens dysferlin-interacting
protein 1 protein.
Length = 154
Score = 76.2 bits (179), Expect = 3e-13
Identities = 34/70 (48%), Positives = 46/70 (65%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + NL+ V+ LV +GAD+++ D GWTPLH S G+ IARYL+ GAD A N DG
Sbjct: 71 AVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRDATNDDG 130
Query: 63 ELPVDIAESD 72
+LP D+ + D
Sbjct: 131 DLPSDLIDPD 140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
+G LH A G ++ K L++ AD D GWTPLH A G + A L+ GA
Sbjct: 63 SGLAALHEAVLSGNLECVKLLVK-YGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121
Query: 180 DPHLKNYSGQTCLDLVDPSISSWLE 204
D N G DL+DP +E
Sbjct: 122 DRDATNDDGDLPSDLIDPDYKELVE 146
Score = 34.7 bits (76), Expect = 0.93
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTP 158
+ RD + G TPLH+A + GY D+A+ L+ AD D + +G P
Sbjct: 90 IHQRD-EAGWTPLHIACSDGYPDIARYLI-SLGADRDATNDDGDLP 133
>AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protein 1
protein.
Length = 1431
Score = 75.8 bits (178), Expect = 4e-13
Identities = 66/208 (31%), Positives = 99/208 (47%), Gaps = 17/208 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A ++ N +++ L+ A V+ DN+G PLH A G + +L++G+ V + +G
Sbjct: 56 AALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEG 115
Query: 63 ELPVDIAES----DAMADLLQK-----VIDEKG-----VDCEKSRNAEVDTLMSDAREWA 108
+P+ +A D LLQ ++D G + CE R V L+S A
Sbjct: 116 HIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAA 175
Query: 109 LHGYVEVRDLKTGGT-PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
L GT PLH+AA G+ID+ + LL+ D + G T LH AAL G+
Sbjct: 176 LLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQ-AGIDINRQTKSG-TALHEAALCGK 233
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
E LLL G + H++N QT LD+V
Sbjct: 234 TEVVRLLLDSGINAHVRNTYSQTALDIV 261
Score = 43.2 bits (97), Expect = 0.003
Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 24/191 (12%)
Query: 17 THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMAD 76
T +VN D +G++ LH A G + LLE+ A V + G P+ A +
Sbjct: 37 TKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKE 96
Query: 77 LLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL------------KTGGTP 124
++ V+ S + ++ A HG+ +V ++ +G TP
Sbjct: 97 PMKLVLKAGSAVNIPSDEGHIPLHLA-----AQHGHYDVSEMLLQHQSNPCMVDNSGKTP 151
Query: 125 LHVAAAKGYIDVAKTLLED--CNA--DP---DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
L +A G + V + LL C A +P D D G +PLH AA G + LLL+
Sbjct: 152 LDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQA 211
Query: 178 GADPHLKNYSG 188
G D + + SG
Sbjct: 212 GIDINRQTKSG 222
>BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protein 2
protein.
Length = 1202
Score = 75.4 bits (177), Expect = 5e-13
Identities = 60/214 (28%), Positives = 104/214 (48%), Gaps = 17/214 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + +L+++ L+ A V+ D+ G PLH A G + R LL + A V A + DG
Sbjct: 56 AALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDG 115
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDC--EKSRNAEVDTLMSDAR----EWALHGYVEVR 116
++P+ +A ++ + ++ + C K++ +D R + L+ ++ V
Sbjct: 116 QIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVA 175
Query: 117 DLKTGG---------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
L+ TPLH+AA G+ +V + LL + + G T LH AAL+G+
Sbjct: 176 LLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLR-AGIEINRQTKTG-TALHEAALYGK 233
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDPSISS 201
E LLL+ G D +++N QT LD+V+ +S
Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTS 267
Score = 40.7 bits (91), Expect = 0.014
Identities = 28/74 (37%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G + LH AA G +++ LLE A D D G PLH AA G+ E LLL+ A
Sbjct: 49 GFSALHHAALGGSLELIALLLE-AQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA 107
Query: 181 PHLKNYSGQTCLDL 194
+ + GQ L L
Sbjct: 108 VNAASLDGQIPLHL 121
Score = 35.5 bits (78), Expect = 0.53
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++NR G T LH A G + R LLE G DV N + +DI
Sbjct: 203 EVIRQLLRAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIV 261
Query: 70 E----SDAMADLLQKVIDEKGV 87
S A ++ Q + + G+
Sbjct: 262 NQFTTSQASREIKQLLREASGI 283
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 75.4 bits (177), Expect = 5e-13
Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+ + L + G++ N D E TPLH A G S+A+ L E+G +V N +GE P+ A
Sbjct: 13 DVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTA 72
Query: 70 ESDAMADLLQKVIDEKGVD---CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKT 120
+ D+++ + E G D C+K + + M + G +V+ +D +
Sbjct: 73 SARGYHDIVE-CLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RH 130
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLHVA G + + L E N + D + G TPLH AA G + L GA
Sbjct: 131 GNTPLHVACKDGNMPIVVALCE-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGAS 189
Query: 181 PHLKNYSGQTCLDL 194
G+T DL
Sbjct: 190 VEALTTDGKTAEDL 203
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 138 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 197
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 198 KTAEDLARSE 207
Score = 49.2 bits (112), Expect = 4e-05
Identities = 29/68 (42%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LHVAA G+ DVA+ LL ++P+ D E TPLH AA G A L + G + ++K
Sbjct: 3 LHVAARYGHADVAQ-LLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIK 61
Query: 185 NYSGQTCL 192
N G+T L
Sbjct: 62 NREGETPL 69
>AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protein 2
protein.
Length = 1202
Score = 75.4 bits (177), Expect = 5e-13
Identities = 60/214 (28%), Positives = 104/214 (48%), Gaps = 17/214 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + +L+++ L+ A V+ D+ G PLH A G + R LL + A V A + DG
Sbjct: 56 AALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDG 115
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDC--EKSRNAEVDTLMSDAR----EWALHGYVEVR 116
++P+ +A ++ + ++ + C K++ +D R + L+ ++ V
Sbjct: 116 QIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVA 175
Query: 117 DLKTGG---------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
L+ TPLH+AA G+ +V + LL + + G T LH AAL+G+
Sbjct: 176 LLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLR-AGIEINRQTKTG-TALHEAALYGK 233
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDPSISS 201
E LLL+ G D +++N QT LD+V+ +S
Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTS 267
Score = 40.7 bits (91), Expect = 0.014
Identities = 28/74 (37%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G + LH AA G +++ LLE A D D G PLH AA G+ E LLL+ A
Sbjct: 49 GFSALHHAALGGSLELIALLLE-AQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAA 107
Query: 181 PHLKNYSGQTCLDL 194
+ + GQ L L
Sbjct: 108 VNAASLDGQIPLHL 121
Score = 35.5 bits (78), Expect = 0.53
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++NR G T LH A G + R LLE G DV N + +DI
Sbjct: 203 EVIRQLLRAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIV 261
Query: 70 E----SDAMADLLQKVIDEKGV 87
S A ++ Q + + G+
Sbjct: 262 NQFTTSQASREIKQLLREASGI 283
>BC071166-1|AAH71166.1| 142|Homo sapiens PPP1R12B protein protein.
Length = 142
Score = 74.9 bits (176), Expect = 7e-13
Identities = 31/43 (72%), Positives = 39/43 (90%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIA 45
ACID+NLDMV+FLV + A+VN+ DNEGWTPLHA ASCG+++IA
Sbjct: 98 ACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIA 140
Score = 40.3 bits (90), Expect = 0.019
Identities = 21/71 (29%), Positives = 38/71 (53%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++AC + D V L+ GAD+N + +G T LH + + ++L+E+ A+V +
Sbjct: 63 LAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDN 122
Query: 61 DGELPVDIAES 71
+G P+ A S
Sbjct: 123 EGWTPLHAAAS 133
Score = 39.9 bits (89), Expect = 0.025
Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G T LH A +D+ K L+E+ A+ + D EGWTPLHAAA G
Sbjct: 91 GLTALHQACIDENLDMVKFLVEN-RANVNQQDNEGWTPLHAAASCG 135
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 74.1 bits (174), Expect = 1e-12
Identities = 61/195 (31%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+VE L+ VN D + WT LH A G S R LLE A V V+++G P+ +A
Sbjct: 486 VVERLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVAC 545
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-----------GYVEVRDLK 119
+++ +++ +GVD S + L W H G
Sbjct: 546 QHGQENIV-RILLRRGVDV--SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL 602
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G TPLH+AA +G+ VA+ L++ C +D + TPLH AA G A LLL GA
Sbjct: 603 DGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGA 661
Query: 180 DPHLKNYSGQTCLDL 194
G T L L
Sbjct: 662 GKEAVTSDGYTALHL 676
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/193 (29%), Positives = 78/193 (40%), Gaps = 28/193 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLL-ESGADVAAVNYD 61
AC ++V L+ G DV+ + W PLH A G + I + L + G V A D
Sbjct: 544 ACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLD 603
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G P+ +A + + +ID L SD +L
Sbjct: 604 GRTPLHLAAQRGHYRVARILID----------------LCSDVNVCSL----------LA 637
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPLHVAA G+ A+ LL A + V +G+T LH AA G LL++ AD
Sbjct: 638 QTPLHVAAETGHTSTARLLLHR-GAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV 696
Query: 182 HLKNYSGQTCLDL 194
+ QT L L
Sbjct: 697 LARGPLNQTALHL 709
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 14/192 (7%)
Query: 8 NLDMVEFLVTH-GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+L +V+ L G VN +G TPLH A G +AR L++ +DV + + P+
Sbjct: 582 HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPL 641
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHG----YVEVRDLKTGG 122
+A + ++ +G E + L AR L E D+ G
Sbjct: 642 HVAAETGHTSTARLLL-HRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 700
Query: 123 ----TPLHVAAAKGYIDVAKTLLEDCNADP-DCVDYEGWTPLHAAALWGQKEAAALLLKF 177
T LH+AAA G+ +V + L+ +AD D D +G + LH AA + LL+
Sbjct: 701 PLNQTALHLAAAHGHSEVVEELV---SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRH 757
Query: 178 GADPHLKNYSGQ 189
GA +L++ Q
Sbjct: 758 GAHINLQSLKFQ 769
Score = 42.7 bits (96), Expect = 0.003
Identities = 43/182 (23%), Positives = 73/182 (40%), Gaps = 9/182 (4%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
DV+ + G + LH G A++LL + A+ N G P+ +A + ++++
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVER 489
Query: 81 V------IDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG-TPLHVAAAKGY 133
+ ++ K D + + + L V ++ G TP+HVA G
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQ 549
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKF-GADPHLKNYSGQTCL 192
++ + LL D + W PLH AA G LL K G + + G+T L
Sbjct: 550 ENIVRILLRR-GVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPL 608
Query: 193 DL 194
L
Sbjct: 609 HL 610
Score = 40.3 bits (90), Expect = 0.019
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 8/162 (4%)
Query: 35 ATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
A +S G +S++ S +D+ + + VD S + L+ K++ + VD
Sbjct: 380 AFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLM-KILQPQDVDLALDSG 438
Query: 95 AE-----VDTLMSDAREWALHGYVEVR-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP 148
A V+ + +W L + G TPLH+A + V + LL
Sbjct: 439 ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLAR-KISV 497
Query: 149 DCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
+ D + WT LH AA G + + LLL+ A + ++ G T
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLT 539
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 595
>BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein.
Length = 581
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 34.7 bits (76), Expect = 0.93
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASC-GFISIARYLLESGADV 55
M A + + +MV L+ GA++N E A C GF +A +L+++GAD+
Sbjct: 476 MEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI 531
Score = 33.9 bits (74), Expect = 1.6
Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA 57
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINA 499
Score = 33.1 bits (72), Expect = 2.8
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++ +FL+ GAD+ G + TPL + G + + +YLL SG +Y G
Sbjct: 512 ACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLLASGQAGGHEDYFG 568
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 595
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 595
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 616
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 301 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 360
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 361 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 415
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 416 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 474
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 475 MVALLLAQGAN 485
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 368 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 427
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 428 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 486
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 487 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 542
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 543 LLASGANVHATTATGDTAL 561
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 266 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 325
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 326 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 385
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 386 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 443
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 444 ALLIERGANLEEVNDEGYTPL 464
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 234 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 293
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 294 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 348
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 349 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 407
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 408 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 452
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 201 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 260
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 261 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 294
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 295 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 351
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 433 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 491
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 492 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 550
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 551 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 584
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 595
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 326 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 385
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 386 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 440
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 441 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 499
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 500 MVALLLAQGAN 510
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 393 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 452
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 453 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 511
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 512 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 567
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 568 LLASGANVHATTATGDTAL 586
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 291 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 350
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 351 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 410
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 411 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 468
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 469 ALLIERGANLEEVNDEGYTPL 489
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 1162 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1221
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 1222 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 1276
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 1277 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 1334
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 1335 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1394
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 1395 LMSAFRKGHVKVVQYLVKEVN 1415
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/191 (27%), Positives = 89/191 (46%), Gaps = 12/191 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++ +FL+ GAD+ G + TPL + G + + +YLL SGA+V A G
Sbjct: 526 ACCGGFSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATG 582
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D +K ++ T++ + + A H + + + G
Sbjct: 583 DTALTYACENGHTDVAD-VLLQAGADLDKQE--DMKTIL-EGIDPAKH---QEHESEGGR 635
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA G++ + L+ + N + + + T + A G LLL GADP
Sbjct: 636 TPLMKAARAGHLCTVQFLISKGANVNRATANNDH-TVVSLACAGGHLAVVELLLAHGADP 694
Query: 182 HLKNYSGQTCL 192
+ G T L
Sbjct: 695 THRLKDGSTML 705
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 259 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 318
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 319 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 373
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 374 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 432
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 433 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 477
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 1095 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 1154
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 1155 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 1209
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 1210 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 1268
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 1269 RAEVVSLLLDRKANVEHRAKTGLTPL 1294
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 226 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 285
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 286 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 319
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 320 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 376
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 1114 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 1172
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 1173 LLLARGANKEHRNVSDYTPLSL 1194
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 458 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 516
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 517 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 575
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 576 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 609
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV 58
AC +L +VE L+ HGAD +G T L A G ++ YLL+ +V +V
Sbjct: 675 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSV 730
Score = 33.9 bits (74), Expect = 1.6
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGD-NEGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A +L V+FL++ GA+VNR N T + + G +++ LL GAD
Sbjct: 639 MKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL 698
Query: 60 YDGELPVDIAESDAMADLLQKVID 83
DG + A +++ ++D
Sbjct: 699 KDGSTMLIEAAKGGHTNVVSYLLD 722
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 120 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 179
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 180 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 234
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 235 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 293
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 294 MVALLLAQGAN 304
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 187 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 246
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 247 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 305
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 306 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 361
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 362 LLASGANVHATTATGDTAL 380
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 85 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 144
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 145 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 204
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 205 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 262
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 263 ALLIERGANLEEVNDEGYTPL 283
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 53 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 112
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 113 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 167
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 168 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 226
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 227 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 271
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 20 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 79
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 80 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 113
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 114 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 170
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 252 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 310
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 311 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 369
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 370 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 403
>AF392450-1|AAL40663.1| 950|Homo sapiens oxysterol-binding
protein-like protein OSBPL1B protein.
Length = 950
Score = 73.7 bits (173), Expect = 2e-12
Identities = 58/181 (32%), Positives = 87/181 (48%), Gaps = 6/181 (3%)
Query: 20 ADVN-RG---DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
AD+N +G N GWTPLH G + + LL++GA+V +N G+ P+ A
Sbjct: 35 ADINCKGRSKSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRK 94
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-ALHGYVEVRDLKTGGTPLHVAAAKGYI 134
+L+ +++ + + + ++ A E ++ VE + L AA +G
Sbjct: 95 ELVMLLLEYNADTTIVNGSGQTAKEVTHAEEIRSMLEAVERTQQRKLEELLLAAAREGKT 154
Query: 135 DVAKTLLEDCNA-DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
LL N D +C D G TPLH AA K+ A LL+ GADP+LKN + Q LD
Sbjct: 155 TELTALLNRPNPPDVNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLD 214
Query: 194 L 194
L
Sbjct: 215 L 215
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A G+ V + LL+ A+ + ++ G TPLH AA G+KE LLL++ AD
Sbjct: 48 GWTPLHLACYFGHRQVVQDLLK-AGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNAD 106
Query: 181 PHLKNYSGQTCLDLVD-PSISSWLEEAALKAPRRV 214
+ N SGQT ++ I S LE R++
Sbjct: 107 TTIVNGSGQTAKEVTHAEEIRSMLEAVERTQQRKL 141
Score = 52.4 bits (120), Expect = 4e-06
Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 18/170 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +V+ L+ GA+VN ++ G TPLH A G + LLE AD VN G
Sbjct: 55 ACYFGHRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTIVNGSG 114
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGYVEVR 116
+ ++ ++ + +L+ V+ + R E + L++ ARE AL
Sbjct: 115 QTAKEVTHAEEIRSMLE------AVERTQQRKLE-ELLLAAAREGKTTELTALLNRPNPP 167
Query: 117 DL----KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
D+ + G TPLH AA + + A LL ADP+ + PL A
Sbjct: 168 DVNCSDQLGNTPLHCAAYRAHKQCALKLLRS-GADPNLKNKNDQKPLDLA 216
Score = 39.9 bits (89), Expect = 0.025
Identities = 23/58 (39%), Positives = 29/58 (50%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
DVN D G TPLH A A LL SGAD N + + P+D+A+ M +L
Sbjct: 168 DVNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLDLAQGAEMKHIL 225
>AF323726-1|AAG53407.2| 927|Homo sapiens OSBP-related protein 1
protein.
Length = 927
Score = 73.7 bits (173), Expect = 2e-12
Identities = 58/181 (32%), Positives = 87/181 (48%), Gaps = 6/181 (3%)
Query: 20 ADVN-RG---DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
AD+N +G N GWTPLH G + + LL++GA+V +N G+ P+ A
Sbjct: 35 ADINCKGRSKSNLGWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRK 94
Query: 76 DLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW-ALHGYVEVRDLKTGGTPLHVAAAKGYI 134
+L+ +++ + + + ++ A E ++ VE + L AA +G
Sbjct: 95 ELVMLLLEYNADTTIVNGSGQTAKEVTHAEEIRSMLEAVERTQQRKLEELLLAAAREGKT 154
Query: 135 DVAKTLLEDCNA-DPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
LL N D +C D G TPLH AA K+ A LL+ GADP+LKN + Q LD
Sbjct: 155 TELTALLNRPNPPDVNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLD 214
Query: 194 L 194
L
Sbjct: 215 L 215
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPLH+A G+ V + LL+ A+ + ++ G TPLH AA G+KE LLL++ AD
Sbjct: 48 GWTPLHLACYFGHRQVVQDLLK-AGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNAD 106
Query: 181 PHLKNYSGQTCLDLVD-PSISSWLEEAALKAPRRV 214
+ N SGQT ++ I S LE R++
Sbjct: 107 TTIVNGSGQTAKEVTHAEEIRSMLEAVERTQQRKL 141
Score = 52.4 bits (120), Expect = 4e-06
Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 18/170 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +V+ L+ GA+VN ++ G TPLH A G + LLE AD VN G
Sbjct: 55 ACYFGHRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTIVNGSG 114
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE------WALHGYVEVR 116
+ ++ ++ + +L+ V+ + R E + L++ ARE AL
Sbjct: 115 QTAKEVTHAEEIRSMLE------AVERTQQRKLE-ELLLAAAREGKTTELTALLNRPNPP 167
Query: 117 DL----KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAA 162
D+ + G TPLH AA + + A LL ADP+ + PL A
Sbjct: 168 DVNCSDQLGNTPLHCAAYRAHKQCALKLLRS-GADPNLKNKNDQKPLDLA 216
Score = 39.9 bits (89), Expect = 0.025
Identities = 23/58 (39%), Positives = 29/58 (50%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
DVN D G TPLH A A LL SGAD N + + P+D+A+ M +L
Sbjct: 168 DVNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLDLAQGAEMKHIL 225
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 73.7 bits (173), Expect = 2e-12
Identities = 62/191 (32%), Positives = 101/191 (52%), Gaps = 19/191 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAA-VNYD 61
AC +D+V+ L+ GA++ + G TPL AS G + +AR LL+ GA + N
Sbjct: 312 ACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF 371
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
E + +A D+++ ++ E G D ++ + E+ T + +A + G+VEV R L
Sbjct: 372 KESALTLACYKGHLDMVRFLL-EAGAD-QEHKTDEMHTALMEA---CMDGHVEVARLLLD 426
Query: 121 GG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKE 169
G +PL +AA G++++A L+E A+ + V+ EG+TPL AA G +E
Sbjct: 427 SGAQVNMPADSFESPLTLAACGGHVELAALLIER-GANLEEVNDEGYTPLMEAAREGHEE 485
Query: 170 AAALLLKFGAD 180
ALLL GA+
Sbjct: 486 MVALLLAQGAN 496
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 39.5 bits (88), Expect = 0.033
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
TG T L A G+ DVA LL+ AD D
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLD 595
>AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein.
Length = 1249
Score = 72.9 bits (171), Expect = 3e-12
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 12/203 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+V L+ + A N DN+G+ P+H A G + I + L+ G + V N
Sbjct: 66 AALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQN 125
Query: 60 YDGELPVDIA----ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--EWALHGYV 113
+ E + A S+ +A LL+++ D + + ++ L R + + +
Sbjct: 126 NENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIISAHP 185
Query: 114 EVRDLKT-GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+ T TPLH+AA G+ V + LLE D C +G + LH AAL+G+ +
Sbjct: 186 NLMSCNTRKHTPLHLAARNGHKAVVQVLLE-AGMDVSCQTEKG-SALHEAALFGKVDVVR 243
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
+LL+ G D ++K+ G+T LD++
Sbjct: 244 VLLETGIDANIKDSLGRTVLDIL 266
Score = 45.6 bits (103), Expect = 5e-04
Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 19/187 (10%)
Query: 16 VTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMA 75
+ G +VN D+ G+T LH A G I LL+ A + G P+ +A
Sbjct: 46 IWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDV 105
Query: 76 DLLQKVIDEKGVDCEK--SRNAEVDTLMSDAREWALHGYVEV----------RDLKTGGT 123
+++ K++ G + +N E +T + A ++ V V R+ K T
Sbjct: 106 EIV-KILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKL-ET 163
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PL +AA G + V K ++ +A P+ + + TPLH AA G K +LL+ G D
Sbjct: 164 PLDLAALYGRLRVVKMII---SAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDV 220
Query: 182 HLKNYSG 188
+ G
Sbjct: 221 SCQTEKG 227
Score = 31.9 bits (69), Expect = 6.5
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+V+ L+ G DV+ +G + LH A G + + R LLE+G D + G +DI +
Sbjct: 209 VVQVLLEAGMDVSCQTEKG-SALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILK 267
Query: 71 SDAMADLLQ 79
LQ
Sbjct: 268 EHPSQKSLQ 276
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 71.3 bits (167), Expect = 9e-12
Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 10/224 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
LD ++FLV G D N D EG T LH A G +++ + L++ G D+ N +G +
Sbjct: 78 LDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHS 137
Query: 69 AESDAMADLLQKVIDEKG-VDCEKSRNAEVDTLMS-----DAREWALH--GYVEVRDLKT 120
A + D +Q ++ V+ +N + D +H G V D +
Sbjct: 138 AAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQ- 196
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLH+A + + + L+ ++D + VD TPLH AA ++ A +LL G D
Sbjct: 197 GASPLHLAVRHNFPALVRLLINS-DSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 255
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
+L++ G+T L + S L + +KA R K S P
Sbjct: 256 LNLRDEQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDP 299
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 29/187 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD--GELP 65
+L +++ LV GA ++ +G T LH A G + + +++E DVA + D G
Sbjct: 9 HLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTA 68
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPL 125
A D L ++ G C+ + V+D K G T L
Sbjct: 69 FHRAAEHGQLDALDFLV---GSGCDHN----------------------VKD-KEGNTAL 102
Query: 126 HVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
H+AA +G++ V + L+ D D + + EG T LH+AA + LLL+ G+ +
Sbjct: 103 HLAAGRGHMAVLQRLV-DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALT 161
Query: 186 YSGQTCL 192
+CL
Sbjct: 162 QKNLSCL 168
Score = 42.3 bits (95), Expect = 0.005
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + D+ L+ G N D++G +PLH F ++ R L+ S +DV AV+
Sbjct: 171 AALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQ 230
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ P+ +A A D+ ++ GVD
Sbjct: 231 QTPLHLAAEHAWQDIADMLL-IAGVD 255
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 71.3 bits (167), Expect = 9e-12
Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 10/224 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
LD ++FLV G D N D EG T LH A G +++ + L++ G D+ N +G +
Sbjct: 81 LDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHS 140
Query: 69 AESDAMADLLQKVIDEKG-VDCEKSRNAEVDTLMS-----DAREWALH--GYVEVRDLKT 120
A + D +Q ++ V+ +N + D +H G V D +
Sbjct: 141 AAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQ- 199
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLH+A + + + L+ ++D + VD TPLH AA ++ A +LL G D
Sbjct: 200 GASPLHLAVRHNFPALVRLLINS-DSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
+L++ G+T L + S L + +KA R K S P
Sbjct: 259 LNLRDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDP 302
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 29/187 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD--GELP 65
+L +++ LV GA ++ +G T LH A G + + +++E DVA + D G
Sbjct: 12 HLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTA 71
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPL 125
A D L ++ G C+ + V+D K G T L
Sbjct: 72 FHRAAEHGQLDALDFLV---GSGCDHN----------------------VKD-KEGNTAL 105
Query: 126 HVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
H+AA +G++ V + L+ D D + + EG T LH+AA + LLL+ G+ +
Sbjct: 106 HLAAGRGHMAVLQRLV-DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALT 164
Query: 186 YSGQTCL 192
+CL
Sbjct: 165 QKNLSCL 171
Score = 42.3 bits (95), Expect = 0.005
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + D+ L+ G N D++G +PLH F ++ R L+ S +DV AV+
Sbjct: 174 AALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQ 233
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ P+ +A A D+ ++ GVD
Sbjct: 234 QTPLHLAAEHAWQDIADMLL-IAGVD 258
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 71.3 bits (167), Expect = 9e-12
Identities = 63/224 (28%), Positives = 102/224 (45%), Gaps = 10/224 (4%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
LD ++FLV G D N D EG T LH A G +++ + L++ G D+ N +G +
Sbjct: 81 LDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHS 140
Query: 69 AESDAMADLLQKVIDEKG-VDCEKSRNAEVDTLMS-----DAREWALH--GYVEVRDLKT 120
A + D +Q ++ V+ +N + D +H G V D +
Sbjct: 141 AAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQ- 199
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLH+A + + + L+ ++D + VD TPLH AA ++ A +LL G D
Sbjct: 200 GASPLHLAVRHNFPALVRLLINS-DSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 181 PHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
+L++ G+T L + S L + +KA R K S P
Sbjct: 259 LNLRDEQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDP 302
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 29/187 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD--GELP 65
+L +++ LV GA ++ +G T LH A G + + +++E DVA + D G
Sbjct: 12 HLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTA 71
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPL 125
A D L ++ G C+ + V+D K G T L
Sbjct: 72 FHRAAEHGQLDALDFLV---GSGCDHN----------------------VKD-KEGNTAL 105
Query: 126 HVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
H+AA +G++ V + L+ D D + + EG T LH+AA + LLL+ G+ +
Sbjct: 106 HLAAGRGHMAVLQRLV-DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALT 164
Query: 186 YSGQTCL 192
+CL
Sbjct: 165 QKNLSCL 171
Score = 42.3 bits (95), Expect = 0.005
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + D+ L+ G N D++G +PLH F ++ R L+ S +DV AV+
Sbjct: 174 AALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQ 233
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ P+ +A A D+ ++ GVD
Sbjct: 234 QTPLHLAAEHAWQDIADMLL-IAGVD 258
>BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 27
(VPS9 domain) protein.
Length = 1050
Score = 70.9 bits (166), Expect = 1e-11
Identities = 66/214 (30%), Positives = 95/214 (44%), Gaps = 33/214 (15%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEK 85
D+ G TPLH A CG S+ L+ GA V A +Y G P+ +A
Sbjct: 460 DDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLA---------------- 503
Query: 86 GVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLL---- 141
C+K + V L+ + A EV+D G TPLH+A G+ D K L+
Sbjct: 504 ---CQKGYQS-VTLLLLHYKASA-----EVQD-NNGNTPLHLACTYGHEDCVKALVYYDV 553
Query: 142 EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD-LVDPSIS 200
E C D + +G TPLH AA WG + LL+ GA ++N +T L ++ I
Sbjct: 554 ESCRLDIG--NEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKIL 611
Query: 201 SWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
S +E L RR +++ + P+ V I E
Sbjct: 612 SVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQE 645
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/69 (44%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH+A +G+ V K LL D NA P+ D G TPL A G E ALLL+ GA +
Sbjct: 780 PLHLACQQGHFQVVKCLL-DSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINA 838
Query: 184 KNYSGQTCL 192
N G T L
Sbjct: 839 SNNKGNTAL 847
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ HGA +N +N+G T LH + + LL GA V +N
Sbjct: 817 ACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQ 876
Query: 63 ELPVDIAESDA-MADLLQKV 81
VD AE ++ + +LLQ V
Sbjct: 877 RTAVDCAEQNSKIMELLQVV 896
Score = 41.1 bits (92), Expect = 0.011
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLHVAA G D+ LL+ A+ + + PLH A G + LL A
Sbjct: 744 GSSPLHVAALHGRADLIPLLLKH-GANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAK 802
Query: 181 PHLKNYSGQTCL 192
P+ K+ SG T L
Sbjct: 803 PNKKDLSGNTPL 814
Score = 38.7 bits (86), Expect = 0.057
Identities = 45/178 (25%), Positives = 75/178 (42%), Gaps = 27/178 (15%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G VN +G +PLH A G + LL+ GA+ A N D +P+ +A ++
Sbjct: 734 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVV 793
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAK 138
+ ++D NA+ + +DL +G TPL A + G+ ++
Sbjct: 794 KCLLDS---------NAKPNK----------------KDL-SGNTPLIYACSGGHHELVA 827
Query: 139 TLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVD 196
LL+ A + + +G T LH A + LLL GA + N +T +D +
Sbjct: 828 LLLQH-GASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAE 884
Score = 36.7 bits (81), Expect = 0.23
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + D++ L+ HGA+ + + PLH G + + LL+S A + G
Sbjct: 751 AALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSG 810
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
P+ A S +L+ ++ + G S N
Sbjct: 811 NTPLIYACSGGHHELVALLL-QHGASINASNN 841
Score = 35.9 bits (79), Expect = 0.40
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNR---GDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
AC + D V+ LV + + R G+ +G TPLH A G+ + LL++GA N
Sbjct: 536 ACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQN 595
Query: 60 YDGELPVDIAESDAMADLLQ 79
E P+ A + + +++
Sbjct: 596 RLKETPLKCALNSKILSVME 615
Score = 33.9 bits (74), Expect = 1.6
Identities = 20/60 (33%), Positives = 28/60 (46%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +V+ L+ A N+ D G TPL S G + LL+ GA + A N G
Sbjct: 784 ACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKG 843
>AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein.
Length = 1060
Score = 70.9 bits (166), Expect = 1e-11
Identities = 66/214 (30%), Positives = 95/214 (44%), Gaps = 33/214 (15%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEK 85
D+ G TPLH A CG S+ L+ GA V A +Y G P+ +A
Sbjct: 470 DDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLA---------------- 513
Query: 86 GVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLL---- 141
C+K + V L+ + A EV+D G TPLH+A G+ D K L+
Sbjct: 514 ---CQKGYQS-VTLLLLHYKASA-----EVQD-NNGNTPLHLACTYGHEDCVKALVYYDV 563
Query: 142 EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD-LVDPSIS 200
E C D + +G TPLH AA WG + LL+ GA ++N +T L ++ I
Sbjct: 564 ESCRLDIG--NEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKIL 621
Query: 201 SWLEEAALKAPRRVNNNKRKLSPPRHEVKRIDIE 234
S +E L RR +++ + P+ V I E
Sbjct: 622 SVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQE 655
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/69 (44%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 124 PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHL 183
PLH+A +G+ V K LL D NA P+ D G TPL A G E ALLL+ GA +
Sbjct: 790 PLHLACQQGHFQVVKCLL-DSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINA 848
Query: 184 KNYSGQTCL 192
N G T L
Sbjct: 849 SNNKGNTAL 857
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ HGA +N +N+G T LH + + LL GA V +N
Sbjct: 827 ACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQ 886
Query: 63 ELPVDIAESDA-MADLLQKV 81
VD AE ++ + +LLQ V
Sbjct: 887 RTAVDCAEQNSKIMELLQVV 906
Score = 41.1 bits (92), Expect = 0.011
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLHVAA G D+ LL+ A+ + + PLH A G + LL A
Sbjct: 754 GSSPLHVAALHGRADLIPLLLKH-GANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAK 812
Query: 181 PHLKNYSGQTCL 192
P+ K+ SG T L
Sbjct: 813 PNKKDLSGNTPL 824
Score = 38.7 bits (86), Expect = 0.057
Identities = 45/178 (25%), Positives = 75/178 (42%), Gaps = 27/178 (15%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G VN +G +PLH A G + LL+ GA+ A N D +P+ +A ++
Sbjct: 744 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVV 803
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAK 138
+ ++D NA+ + +DL +G TPL A + G+ ++
Sbjct: 804 KCLLDS---------NAKPNK----------------KDL-SGNTPLIYACSGGHHELVA 837
Query: 139 TLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVD 196
LL+ A + + +G T LH A + LLL GA + N +T +D +
Sbjct: 838 LLLQH-GASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAE 894
Score = 36.7 bits (81), Expect = 0.23
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + D++ L+ HGA+ + + PLH G + + LL+S A + G
Sbjct: 761 AALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSG 820
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRN 94
P+ A S +L+ ++ + G S N
Sbjct: 821 NTPLIYACSGGHHELVALLL-QHGASINASNN 851
Score = 35.9 bits (79), Expect = 0.40
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNR---GDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
AC + D V+ LV + + R G+ +G TPLH A G+ + LL++GA N
Sbjct: 546 ACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQN 605
Query: 60 YDGELPVDIAESDAMADLLQ 79
E P+ A + + +++
Sbjct: 606 RLKETPLKCALNSKILSVME 625
Score = 33.9 bits (74), Expect = 1.6
Identities = 20/60 (33%), Positives = 28/60 (46%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +V+ L+ A N+ D G TPL S G + LL+ GA + A N G
Sbjct: 794 ACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKG 853
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 70.5 bits (165), Expect = 2e-11
Identities = 70/235 (29%), Positives = 116/235 (49%), Gaps = 21/235 (8%)
Query: 10 DMVEFLVTHGAD-VNRGDNEGWTPLHATASCGFISIARYLLESG--ADVAAV-NYDGELP 65
+ VE L HGA + + WTPLHA A+ G L++SG AD+ V + G+ P
Sbjct: 61 ECVEVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTP 120
Query: 66 VDIAESDAMADLLQKVIDEKGVDCE----KSRNAEVDTLMSDAREW--AL---HGYVEVR 116
+ +A + D + ++ EKG + + R A ++ + AL +V R
Sbjct: 121 LMLAIMNGHVDCVHLLL-EKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCR 179
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDC-NADP-DC-VDYEGWTPLHAAALWGQKEAAAL 173
D K G TP+H+A+A G+ V +TLL+ + DP D VDY G++P+H A+ G ++ L
Sbjct: 180 DFK-GRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLEL 238
Query: 174 LLKFGADPHLKN--YSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH 226
LL+ +L+ ++ C + + ++ + AL A + VN+ K P H
Sbjct: 239 LLEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGA-KIVNSRDTKGRTPLH 292
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 15/205 (7%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A ++ ++D V L+ G+ + D G T LH A G LL+ A V ++
Sbjct: 122 MLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDF 181
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALH-GYVEVRDLK 119
G P+ +A + +L+ ++ + +A VD WA + G+ + +L
Sbjct: 182 KGRTPIHLASACGHTAVLRTLL--QAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELL 239
Query: 120 T---------GG--TPLHVAAAKGYIDVAKTLLEDCNAD-PDCVDYEGWTPLHAAALWGQ 167
G TPLH A + LL A + D +G TPLHAAA
Sbjct: 240 LEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADN 299
Query: 168 KEAAALLLKFGADPHLKNYSGQTCL 192
+LL+ A+ + +++G+T L
Sbjct: 300 VSGLRMLLQHQAEVNATDHTGRTAL 324
Score = 50.0 bits (114), Expect = 2e-05
Identities = 47/153 (30%), Positives = 67/153 (43%), Gaps = 12/153 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
VN D +G TPLHA A +S R LL+ A+V A ++ G + A + ++ +
Sbjct: 280 VNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFL 339
Query: 82 IDEKGVD---CEKSRNAEVDTLMSDARE-WALHGYVEVRDL----KTGGT---PLHVAAA 130
+ D ++++N + S E AL E +DL T PLH+AA
Sbjct: 340 LYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAAR 399
Query: 131 KGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAA 163
G V + LL A VD EG TP A A
Sbjct: 400 NGLASVVQALLSH-GATVLAVDEEGHTPALACA 431
Score = 36.3 bits (80), Expect = 0.30
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
+PLH+AA G+ + KTL E + D D++G T L A G E +L GA
Sbjct: 16 SPLHLAAYNGHCEALKTLAETL-VNLDVRDHKGRTALFLATERGSTECVEVLTAHGASAL 74
Query: 183 LK 184
+K
Sbjct: 75 IK 76
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 27/192 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++VEFL+ G VN D+ GW+PLH AS G I + LL GA V AVN +G
Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A S ++ ++ E G + DA++ + E
Sbjct: 107 CTPLHYAASKNRHEIAVMLL-EGGAN-------------PDAKD-----HYE-------A 140
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T +H AAAKG + + LL A + D EG TPLH A + E A LL+ GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
Query: 183 LKNYSGQTCLDL 194
++N +T L +
Sbjct: 200 IENKEEKTPLQV 211
Score = 51.6 bits (118), Expect = 8e-06
Identities = 53/185 (28%), Positives = 82/185 (44%), Gaps = 27/185 (14%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ E ++ + R D + T LH S G I +LL+ G V + G P+ IA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
S A D + K + KG A+V+ + + G TPLH AA
Sbjct: 81 AS-AGRDEIVKALLGKG--------AQVNAVN-----------------QNGCTPLHYAA 114
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+K ++A LLE A+PD D+ T +H AA G + +LL + A ++++ G
Sbjct: 115 SKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
Query: 190 TCLDL 194
T L L
Sbjct: 174 TPLHL 178
Score = 41.5 bits (93), Expect = 0.008
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A NL M+ L+ + A N D EG TPLH + A+ L+ GA + N +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 63 ELPVDIAESDAMADLLQKVID 83
+ P+ +A+ + +L+++++
Sbjct: 206 KTPLQVAKG-GLGLILKRMVE 225
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 70.1 bits (164), Expect = 2e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 58.0 bits (134), Expect = 9e-08
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.9 bits (84), Expect = 0.099
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 27/192 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++VEFL+ G VN D+ GW+PLH AS G I + LL GA V AVN +G
Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A S ++ ++ E G + DA++ + E
Sbjct: 107 CTPLHYAASKNRHEIAVMLL-EGGAN-------------PDAKD-----HYE-------A 140
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T +H AAAKG + + LL A + D EG TPLH A + E A LL+ GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
Query: 183 LKNYSGQTCLDL 194
++N +T L +
Sbjct: 200 IENKEEKTPLQV 211
Score = 51.6 bits (118), Expect = 8e-06
Identities = 53/185 (28%), Positives = 82/185 (44%), Gaps = 27/185 (14%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ E ++ + R D + T LH S G I +LL+ G V + G P+ IA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
S A D + K + KG A+V+ + + G TPLH AA
Sbjct: 81 AS-AGRDEIVKALLGKG--------AQVNAVN-----------------QNGCTPLHYAA 114
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+K ++A LLE A+PD D+ T +H AA G + +LL + A ++++ G
Sbjct: 115 SKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
Query: 190 TCLDL 194
T L L
Sbjct: 174 TPLHL 178
Score = 41.5 bits (93), Expect = 0.008
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A NL M+ L+ + A N D EG TPLH + A+ L+ GA + N +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 63 ELPVDIAESDAMADLLQKVID 83
+ P+ +A+ + +L+++++
Sbjct: 206 KTPLQVAKG-GLGLILKRMVE 225
>AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 27/192 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++VEFL+ G VN D+ GW+PLH AS G I + LL GA V AVN +G
Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A S ++ ++ E G + DA++ + E
Sbjct: 107 CTPLHYAASKNRHEIAVMLL-EGGAN-------------PDAKD-----HYE-------A 140
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T +H AAAKG + + LL A + D EG TPLH A + E A LL+ GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
Query: 183 LKNYSGQTCLDL 194
++N +T L +
Sbjct: 200 IENKEEKTPLQV 211
Score = 51.6 bits (118), Expect = 8e-06
Identities = 53/185 (28%), Positives = 82/185 (44%), Gaps = 27/185 (14%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ E ++ + R D + T LH S G I +LL+ G V + G P+ IA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
S A D + K + KG A+V+ + + G TPLH AA
Sbjct: 81 AS-AGRDEIVKALLGKG--------AQVNAVN-----------------QNGCTPLHYAA 114
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+K ++A LLE A+PD D+ T +H AA G + +LL + A ++++ G
Sbjct: 115 SKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
Query: 190 TCLDL 194
T L L
Sbjct: 174 TPLHL 178
Score = 41.5 bits (93), Expect = 0.008
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A NL M+ L+ + A N D EG TPLH + A+ L+ GA + N +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 63 ELPVDIAESDAMADLLQKVID 83
+ P+ +A+ + +L+++++
Sbjct: 206 KTPLQVAKG-GLGLILKRMVE 225
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 27/192 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++VEFL+ G VN D+ GW+PLH AS G I + LL GA V AVN +G
Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A S ++ ++ E G + DA++ + E
Sbjct: 107 CTPLHYAASKNRHEIAVMLL-EGGAN-------------PDAKD-----HYE-------A 140
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T +H AAAKG + + LL A + D EG TPLH A + E A LL+ GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
Query: 183 LKNYSGQTCLDL 194
++N +T L +
Sbjct: 200 IENKEEKTPLQV 211
Score = 51.6 bits (118), Expect = 8e-06
Identities = 53/185 (28%), Positives = 82/185 (44%), Gaps = 27/185 (14%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ E ++ + R D + T LH S G I +LL+ G V + G P+ IA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
S A D + K + KG A+V+ + + G TPLH AA
Sbjct: 81 AS-AGRDEIVKALLGKG--------AQVNAVN-----------------QNGCTPLHYAA 114
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+K ++A LLE A+PD D+ T +H AA G + +LL + A ++++ G
Sbjct: 115 SKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
Query: 190 TCLDL 194
T L L
Sbjct: 174 TPLHL 178
Score = 41.5 bits (93), Expect = 0.008
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A NL M+ L+ + A N D EG TPLH + A+ L+ GA + N +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 63 ELPVDIAESDAMADLLQKVID 83
+ P+ +A+ + +L+++++
Sbjct: 206 KTPLQVAKG-GLGLILKRMVE 225
>BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein.
Length = 725
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein.
Length = 895
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein
alternative isoform protein.
Length = 895
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 559
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 560 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 618
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 619 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 662
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog
protein.
Length = 1013
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 297 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 356
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 357 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 390
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 391 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 449
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP-------PRHEVKRIDIEIKGQAEKIVNDXXX 248
+I L+ AA P ++ NN+ + +P RHEV + +E + + D
Sbjct: 450 LDAIKLLLDFAAF--PNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAA 507
Query: 249 XXXXXXXXXXXXXXGRAPSPESTEMAEQQAQNDEAPSWRRSASFRNRQQDSATRIKASSC 308
++ M +Q + D A R + R + R SC
Sbjct: 508 FKIQAVYKGYKVRKA-FRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSC 566
Query: 309 -PSIPPLPQSTLAAIELQKKA--LEPNNSENANTNEDVQTRISP 349
P P ST Q +A +P A E +R SP
Sbjct: 567 RPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSP 610
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 311 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 370
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 371 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 404
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 405 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 463
Query: 182 H 182
+
Sbjct: 464 N 464
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 108 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 167
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 168 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 222
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 223 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 281
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 282 SDDVLRTMLSLKSD 295
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 162 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 220
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 221 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 280
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 281 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 329
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 378 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 437
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 438 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 471
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 1 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 60
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 61 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 120
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 121 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 179
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 180 GNVTVVDVLTSY 191
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 205 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 264
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 265 DSDLEGRT 272
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 31 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 86
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/192 (32%), Positives = 90/192 (46%), Gaps = 27/192 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++VEFL+ G VN D+ GW+PLH AS G I + LL GA V AVN +G
Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNG 106
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
P+ A S ++ ++ E G + DA++ + E
Sbjct: 107 CTPLHYAASKNRHEIAVMLL-EGGAN-------------PDAKD-----HYE-------A 140
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
T +H AAAKG + + LL A + D EG TPLH A + E A LL+ G +
Sbjct: 141 TAMHRAAAKGNLKMIHILLY-YKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIY 199
Query: 183 LKNYSGQTCLDL 194
++N +T L +
Sbjct: 200 IENKEEKTPLQV 211
Score = 51.6 bits (118), Expect = 8e-06
Identities = 53/185 (28%), Positives = 82/185 (44%), Gaps = 27/185 (14%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
++ E ++ + R D + T LH S G I +LL+ G V + G P+ IA
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
S A D + K + KG A+V+ + + G TPLH AA
Sbjct: 81 AS-AGRDEIVKALLGKG--------AQVNAVN-----------------QNGCTPLHYAA 114
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
+K ++A LLE A+PD D+ T +H AA G + +LL + A ++++ G
Sbjct: 115 SKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN 173
Query: 190 TCLDL 194
T L L
Sbjct: 174 TPLHL 178
Score = 39.9 bits (89), Expect = 0.025
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A NL M+ L+ + A N D EG TPLH + A+ L+ G + N +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYIENKEE 205
Query: 63 ELPVDIAESDAMADLLQKVID 83
+ P+ +A+ + +L+++++
Sbjct: 206 KTPLQVAKG-GLGLILKRMVE 225
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 133 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 192
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 193 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 247
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 248 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 305
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 306 TDVVQILLAAGTDVNIKDNHGLTALDTV 333
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 116 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 175
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 176 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 235
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 236 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 292
Query: 187 SG 188
G
Sbjct: 293 MG 294
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 87 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 146
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 147 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 201
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 259
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 260 TDVVQILLAAGTDVNIKDNHGLTALDTV 287
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 190 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 246
Query: 187 SG 188
G
Sbjct: 247 MG 248
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 87 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 146
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 147 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 201
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 259
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 260 TDVVQILLAAGTDVNIKDNHGLTALDTV 287
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 190 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 246
Query: 187 SG 188
G
Sbjct: 247 MG 248
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 87 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 146
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 147 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 201
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 259
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 260 TDVVQILLAAGTDVNIKDNHGLTALDTV 287
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 190 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 246
Query: 187 SG 188
G
Sbjct: 247 MG 248
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 87 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 146
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 147 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 201
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 259
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 260 TDVVQILLAAGTDVNIKDNHGLTALDTV 287
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 190 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 246
Query: 187 SG 188
G
Sbjct: 247 MG 248
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 68.1 bits (159), Expect = 8e-11
Identities = 62/208 (29%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV---N 59
A ++ + D+VE L+ + A N D++G PLH A G I R L+ G V N
Sbjct: 87 AALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQN 146
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
D E + A ++++ +++E + RN + +T + A AL+G +EV +
Sbjct: 147 NDNETALHCAAQYGHTEVVKVLLEE--LTDPTMRNNKFETPLDLA---ALYGRLEVVKML 201
Query: 120 TGG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
TPLH+AA G+ V + LL D D + E + LH AAL+G+
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLL-DAGMDSN-YQTEMGSALHEAALFGK 259
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLV 195
+ +LL G D ++K+ G T LD V
Sbjct: 260 TDVVQILLAAGTDVNIKDNHGLTALDTV 287
Score = 50.8 bits (116), Expect = 1e-05
Identities = 51/182 (28%), Positives = 82/182 (45%), Gaps = 15/182 (8%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G +VN D+ G+TPLH A G + LL + A + G P+ +A A ++
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 79 QKVIDEKGVDCE-KSRNAEVDTLMSDAREWALHGYVEV--RDL-------KTGGTPLHVA 128
+ +I + +N + +T + A ++ V+V +L TPL +A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 129 AAKGYIDVAKTLLEDCNADPDCV--DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
A G ++V K LL NA P+ + + + TPLH AA G K +LL G D + +
Sbjct: 190 ALYGRLEVVKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTE 246
Query: 187 SG 188
G
Sbjct: 247 MG 248
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 1129 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1188
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 1189 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 1244 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 1301
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 1302 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1361
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 1362 LMSAFRKGHVKVVQYLVKEVN 1382
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 1062 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 1121
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 1122 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 1176
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 1177 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 1235
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 1236 RAEVVSLLLDRKANVEHRAKTGLTPL 1261
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 47.2 bits (107), Expect = 2e-04
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 9/186 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TG T L A G+ DVA LL+ AD + G TPL AA G L
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLEHESEGGRTPLMKAARAGHLCTVQFL 620
Query: 175 LKFGAD 180
+ GA+
Sbjct: 621 ISKGAN 626
Score = 43.2 bits (97), Expect = 0.003
Identities = 52/206 (25%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCG-FISIARYLLESGADVAAVN 59
M A + + +MV L+ GA++N E A CG F +A +L+++GAD+
Sbjct: 476 MEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---E 532
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL- 118
P+ A + +L++ ++ G + + A DT ++ A E +G+ +V D+
Sbjct: 533 LGCSTPLMEASQEGHLELVKYLL-ASGANVHAT-TATGDTALTYACE---NGHTDVADVL 587
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWG 166
+ G TPL AA G++ + L+ + N + + + T + A G
Sbjct: 588 LQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDH-TVVSLACAGG 646
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
LLL GADP + G T L
Sbjct: 647 HLAVVELLLAHGADPTHRLKDGSTML 672
Score = 42.3 bits (95), Expect = 0.005
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 540 MEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 599
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDA--------REWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 600 GGRTPLMKAARAGHLCTVQFLI-SKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHG 658
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ +V LL+
Sbjct: 659 ADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 689
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 1081 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 1139
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 1140 LLLARGANKEHRNVSDYTPLSL 1161
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV 58
AC +L +VE L+ HGAD +G T L A G ++ YLL+ +V +V
Sbjct: 642 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSV 697
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 68.1 bits (159), Expect = 8e-11
Identities = 61/199 (30%), Positives = 88/199 (44%), Gaps = 14/199 (7%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC +LDMV FL+ GAD +E T L G + +AR LL+SGA V
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSF 438
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREW---------ALHGYV 113
E P+ +A +L +I E+G + E+ + LM ARE A +
Sbjct: 439 ESPLTLAACGGHVELAALLI-ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANI 497
Query: 114 EVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAAL 173
+ +T T L +A G+ +VA L++ AD ++ TPL A+ G E
Sbjct: 498 NAQTEETQETALTLACCGGFSEVADFLIK-AGAD---IELGCSTPLMEASQEGHLELVKY 553
Query: 174 LLKFGADPHLKNYSGQTCL 192
LL GA+ H +G T L
Sbjct: 554 LLASGANVHATTATGDTAL 572
Score = 62.9 bits (146), Expect = 3e-09
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A LD+V+ L+ H ADVN G T L + GF+ I + LL GA++ N
Sbjct: 277 MAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNE 336
Query: 61 DGELPVDIAESDAMADLLQKVIDE-KGVDCEKSRNAEVDTLMS------DAREWALHGYV 113
+G P+ A S ++ + ++D G++ + E ++ D + L
Sbjct: 337 NGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGA 396
Query: 114 EVRDLKTG--GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
+ ++ KT T L A G+++VA+ LL D A + +PL AA G E A
Sbjct: 397 D-QEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHVELA 454
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
ALL++ GA+ N G T L
Sbjct: 455 ALLIERGANLEEVNDEGYTPL 475
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 1129 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1188
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 1189 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 1244 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 1301
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 1302 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1361
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 1362 LMSAFRKGHVKVVQYLVKEVN 1382
Score = 56.0 bits (129), Expect = 4e-07
Identities = 68/227 (29%), Positives = 105/227 (46%), Gaps = 22/227 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADV-NRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
AC ++ + L+ A+V +RG+ TPL A +S G++ I + LL ADV + +
Sbjct: 245 ACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSAT 304
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-RDLKT 120
G + A + D++ KV+ +G + E N T + +A A G+VEV R L
Sbjct: 305 GNTALTYACAGGFVDIV-KVLLNEGANIE-DHNENGHTPLMEA---ASAGHVEVARVLLD 359
Query: 121 GG------------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G + L +A KG++D+ + LLE AD + E T L A + G
Sbjct: 360 HGAGINTHSNEFKESALTLACYKGHLDMVRFLLE-AGADQEHKTDEMHTALMEACMDGHV 418
Query: 169 EAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
E A LLL GA ++ S ++ L L + +E AAL R N
Sbjct: 419 EVARLLLDSGAQVNMPADSFESPLTLA--ACGGHVELAALLIERGAN 463
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 1062 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 1121
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 1122 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 1176
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 1177 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 1235
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 1236 RAEVVSLLLDRKANVEHRAKTGLTPL 1261
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/178 (28%), Positives = 80/178 (44%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A S D+++ ++ +A+V++ + TG
Sbjct: 272 DITPLMAASSGGYLDIVKLLL---------LHDADVNSQSA-----------------TG 305
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A G++D+ K LL + A+ + + G TPL AA G E A +LL GA
Sbjct: 306 NTALTYACAGGFVDIVKVLLNE-GANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA 362
Score = 47.2 bits (107), Expect = 2e-04
Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 9/186 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV-AAVN 59
++AC ++++ L+ GA++ ++EG+TPL A G + LL GA++ A
Sbjct: 444 LAAC-GGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTE 502
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR----EWALHGYVEV 115
E + +A +++ +I + G D E + + + ++ L V
Sbjct: 503 ETQETALTLACCGGFSEVADFLI-KAGADIELGCSTPLMEASQEGHLELVKYLLASGANV 561
Query: 116 R-DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
TG T L A G+ DVA LL+ AD + G TPL AA G L
Sbjct: 562 HATTATGDTALTYACENGHTDVADVLLQ-AGADLEHESEGGRTPLMKAARAGHLCTVQFL 620
Query: 175 LKFGAD 180
+ GA+
Sbjct: 621 ISKGAN 626
Score = 43.2 bits (97), Expect = 0.003
Identities = 52/206 (25%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCG-FISIARYLLESGADVAAVN 59
M A + + +MV L+ GA++N E A CG F +A +L+++GAD+
Sbjct: 476 MEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---E 532
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL- 118
P+ A + +L++ ++ G + + A DT ++ A E +G+ +V D+
Sbjct: 533 LGCSTPLMEASQEGHLELVKYLL-ASGANVHAT-TATGDTALTYACE---NGHTDVADVL 587
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWG 166
+ G TPL AA G++ + L+ + N + + + T + A G
Sbjct: 588 LQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDH-TVVSLACAGG 646
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
LLL GADP + G T L
Sbjct: 647 HLAVVELLLAHGADPTHRLKDGSTML 672
Score = 42.3 bits (95), Expect = 0.005
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 540 MEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 599
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDA--------REWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 600 GGRTPLMKAARAGHLCTVQFLI-SKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHG 658
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ +V LL+
Sbjct: 659 ADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 689
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 1081 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 1139
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 1140 LLLARGANKEHRNVSDYTPLSL 1161
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV 58
AC +L +VE L+ HGAD +G T L A G ++ YLL+ +V +V
Sbjct: 642 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSV 697
>AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein.
Length = 1124
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/191 (28%), Positives = 92/191 (48%), Gaps = 17/191 (8%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEK 85
D+ G PLH A G + R LL + A V A + DG++P+ +A ++ + ++ +
Sbjct: 1 DSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQ 60
Query: 86 GVDC--EKSRNAEVDTLMSDAR----EWALHGYVEVRDLKTGG---------TPLHVAAA 130
C K++ +D R + L+ ++ V L+ TPLH+AA
Sbjct: 61 SNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAK 120
Query: 131 KGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT 190
G+ +V + LL + + G T LH AAL+G+ E LLL+ G D +++N QT
Sbjct: 121 NGHREVIRQLLR-AGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQT 178
Query: 191 CLDLVDPSISS 201
LD+V+ +S
Sbjct: 179 ALDIVNQFTTS 189
Score = 35.5 bits (78), Expect = 0.53
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++NR G T LH A G + R LLE G DV N + +DI
Sbjct: 125 EVIRQLLRAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIV 183
Query: 70 E----SDAMADLLQKVIDEKGV 87
S A ++ Q + + G+
Sbjct: 184 NQFTTSQASREIKQLLREASGI 205
>DQ224339-1|ABB02425.1| 618|Homo sapiens Ikappa B-zeta variant 3
protein.
Length = 618
Score = 67.7 bits (158), Expect = 1e-10
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA-------DVAAVNYDGE 63
+V+ LV GA VN D G TPLH A G + + ++ GA D+ A NYDG
Sbjct: 395 IVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQ-AIQKGAVGSNQFVDLEATNYDGL 453
Query: 64 LPVDIA--ESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A +A+ LQ+ + ++ + VDT+ + A VE +D
Sbjct: 454 TPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAA---VEAKDR 510
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLE--DCNADPDCVDYEGWTPLHAAA----LWGQKEAAA 172
K+G T LH+AA + +++ + LE C + + Y G T LH AA Q +A
Sbjct: 511 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR 570
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
LL++ GADP +N + + LV
Sbjct: 571 LLMRKGADPSTRNLENEQPVHLV 593
>BC060800-1|AAH60800.1| 718|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor, z
protein.
Length = 718
Score = 67.7 bits (158), Expect = 1e-10
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA-------DVAAVNYDGE 63
+V+ LV GA VN D G TPLH A G + + ++ GA D+ A NYDG
Sbjct: 495 IVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQ-AIQKGAVGSNQFVDLEATNYDGL 553
Query: 64 LPVDIA--ESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A +A+ LQ+ + ++ + VDT+ + A VE +D
Sbjct: 554 TPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAA---VEAKDR 610
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLE--DCNADPDCVDYEGWTPLHAAA----LWGQKEAAA 172
K+G T LH+AA + +++ + LE C + + Y G T LH AA Q +A
Sbjct: 611 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR 670
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
LL++ GADP +N + + LV
Sbjct: 671 LLMRKGADPSTRNLENEQPVHLV 693
>AF548362-1|AAN40698.1| 618|Homo sapiens MAIL-S protein.
Length = 618
Score = 67.7 bits (158), Expect = 1e-10
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA-------DVAAVNYDGE 63
+V+ LV GA VN D G TPLH A G + + ++ GA D+ A NYDG
Sbjct: 395 IVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQ-AIQKGAVGSNQFVDLEATNYDGL 453
Query: 64 LPVDIA--ESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A +A+ LQ+ + ++ + VDT+ + A VE +D
Sbjct: 454 TPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAA---VEAKDR 510
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLE--DCNADPDCVDYEGWTPLHAAA----LWGQKEAAA 172
K+G T LH+AA + +++ + LE C + + Y G T LH AA Q +A
Sbjct: 511 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR 570
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
LL++ GADP +N + + LV
Sbjct: 571 LLMRKGADPSTRNLENEQPVHLV 593
>AB037925-1|BAB40337.1| 718|Homo sapiens MAIL protein.
Length = 718
Score = 67.7 bits (158), Expect = 1e-10
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA-------DVAAVNYDGE 63
+V+ LV GA VN D G TPLH A G + + ++ GA D+ A NYDG
Sbjct: 495 IVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQ-AIQKGAVGSNQFVDLEATNYDGL 553
Query: 64 LPVDIA--ESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A +A+ LQ+ + ++ + VDT+ + A VE +D
Sbjct: 554 TPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAA---VEAKDR 610
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLE--DCNADPDCVDYEGWTPLHAAA----LWGQKEAAA 172
K+G T LH+AA + +++ + LE C + + Y G T LH AA Q +A
Sbjct: 611 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR 670
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
LL++ GADP +N + + LV
Sbjct: 671 LLMRKGADPSTRNLENEQPVHLV 693
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M AC+D ++++ L+ GA VN + +PL A G + +A L+E GA + VN
Sbjct: 439 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 498
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD--L 118
+G P+ A + +++ ++ + G + +T ++ A G++EV D +
Sbjct: 499 EGYTPLMEAAREGHEEMVALLLGQ-GANINAQTEETQETALTLA---CCGGFLEVADFLI 554
Query: 119 KTG-------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G TPL AA +G++++ K LL A+ G T L A G + A
Sbjct: 555 KAGADIELGCSTPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVA 613
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
+LL+ GAD ++ G+T L
Sbjct: 614 DVLLQAGADLEHESEGGRTPL 634
Score = 61.7 bits (143), Expect = 7e-09
Identities = 60/204 (29%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A ++ +V+ L+ H ADVN + G T L + G++ + + LLESGA + N
Sbjct: 306 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 365
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLK 119
+G P+ A S ++ + ++ E G N ++ ++ A G++E VR L
Sbjct: 366 NGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLA---CYKGHLEMVRFLL 421
Query: 120 TGG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G T L A G+++VA+ LL D A + +PL AA G
Sbjct: 422 EAGADQEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHV 480
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E AALL++ GA N G T L
Sbjct: 481 ELAALLIERGASLEEVNDEGYTPL 504
Score = 49.2 bits (112), Expect = 4e-05
Identities = 52/178 (29%), Positives = 77/178 (43%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A + +++ ++ K A+V+ S TG
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHK---------ADVNAQSS-----------------TG 334
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A GY+DV K LLE A + + G TPL A G E A LLL+ GA
Sbjct: 335 NTALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGA 391
Score = 46.4 bits (105), Expect = 3e-04
Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC L++ +FL+ GAD+ G + TPL A G + + +YLL +GA+V A G
Sbjct: 541 ACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATG 597
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D E + + G
Sbjct: 598 DTALTYACENGHTDVAD-VLLQAGADLE-------------------------HESEGGR 631
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA G++ + L+ + N + + + T L A G LLL GADP
Sbjct: 632 TPLMKAARAGHVCTVQFLISKGANVNRTTANNDH-TVLSLACAGGHLAVVELLLAHGADP 690
Query: 182 HLKNYSGQTCL 192
+ G T L
Sbjct: 691 THRLKDGSTML 701
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 569 MEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 628
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 629 GGRTPLMKAARAGHVCTVQFLIS-KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 687
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ V LL+
Sbjct: 688 ADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 718
>BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin
protein.
Length = 604
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/208 (30%), Positives = 96/208 (46%), Gaps = 34/208 (16%)
Query: 21 DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQK 80
D+N D G T LHA A G +S + LLE+ A V A + P+ A D++Q
Sbjct: 349 DINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQT 408
Query: 81 VIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTL 140
+I KG A VD + D G + LH AA G DV + L
Sbjct: 409 LI--KG-------GARVDLVDQD-----------------GHSLLHWAALGGNADVCQIL 442
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQT-----CLDLV 195
+E+ +P+ DY G TPL AA G A+L++ ADP++++ G+T C +
Sbjct: 443 IEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGY 501
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSP 223
+I L+ AA P ++ NN+ + +P
Sbjct: 502 LDAIKLLLDFAAF--PNQMENNEERYTP 527
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 27/181 (14%)
Query: 2 SACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
+A + ++ V+ L+ + A V+ D TPL G + + L++ GA V V+ D
Sbjct: 363 AAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQD 422
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
G + A AD+ Q +I+ K + + +++A G
Sbjct: 423 GHSLLHWAALGGNADVCQILIENK--------------INPNVQDYA------------G 456
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA GYI+ L+E+ NADP+ D EG T LH + G +A LLL F A P
Sbjct: 457 RTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFP 515
Query: 182 H 182
+
Sbjct: 516 N 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 26/194 (13%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASC---GFISIARYLLESGADVAAVN---Y 60
+N + V+ L+ H +++ D EG PLH A+ + R +L++ + +N Y
Sbjct: 160 NNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDY 219
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
+G P+ A +D ++ + E D L WA L G+ ++ L
Sbjct: 220 EGRTPLHFAVADGNVTVVDVL-----TSYESCNITSYDNLFRTPLHWAALLGHAQIVHLL 274
Query: 119 ------------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
G TPLH AA + + K L+ + D D EG T AA G
Sbjct: 275 LERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS-DLEGRTSFMWAAGKG 333
Query: 167 QKEAAALLLKFGAD 180
+ +L +D
Sbjct: 334 SDDVLRTMLSLKSD 347
Score = 38.7 bits (86), Expect = 0.057
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 12/169 (7%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG--ELPVDIAESDAMADLLQ 79
+N D EG TPLH + G +++ +L S +YD P+ A A ++
Sbjct: 214 LNWQDYEGRTPLHFAVADGNVTVVD-VLTSYESCNITSYDNLFRTPLHWAALLGHAQIVH 272
Query: 80 KVID--EKGVDCEKSRNAEV------DTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+++ + G S+ A + + H V+ G T AA K
Sbjct: 273 LLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGK 332
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
G DV +T+L + D + D G T LHAAAL G LLL+ A
Sbjct: 333 GSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNA 381
Score = 37.5 bits (83), Expect = 0.13
Identities = 22/94 (23%), Positives = 43/94 (45%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N D+ + L+ + + N D G TPL A G+I+ L+E+ AD + +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAE 96
+ + ++ D ++ ++D + N E
Sbjct: 490 RTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEE 523
Score = 36.7 bits (81), Expect = 0.23
Identities = 49/192 (25%), Positives = 76/192 (39%), Gaps = 16/192 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M + D LD + L+ GADVN+ D+ T LH A G + LL A+ +
Sbjct: 53 MYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDL 112
Query: 61 DGELPVDIA---ESDAMADLLQKVIDEKGVDC-EKSRNAEV--DTLMSDAREWAL----H 110
+ P+ + S LL K + VD +K++ + ++ L
Sbjct: 113 EEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHD 172
Query: 111 GYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADP-----DCVDYEGWTPLHAAALW 165
+ + D++ G PLH AA T+ +A P + DYEG TPLH A
Sbjct: 173 SNIGIPDVE-GKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 231
Query: 166 GQKEAAALLLKF 177
G +L +
Sbjct: 232 GNVTVVDVLTSY 243
Score = 35.5 bits (78), Expect = 0.53
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G+ + LLE + D +G TPLH AA E + LK +
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKD 316
Query: 183 LKNYSGQT 190
+ G+T
Sbjct: 317 DSDLEGRT 324
Score = 34.7 bits (76), Expect = 0.93
Identities = 24/70 (34%), Positives = 34/70 (48%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+H AA G + L+ +A D D G TPL L + + A LLK GAD +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 185 NYSGQTCLDL 194
++S +T L L
Sbjct: 78 DHSQRTALHL 87
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/57 (42%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T LH+AA KG K LL A+ D E TPLH + ALLLKF A
Sbjct: 83 TALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA 138
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M AC+D ++++ L+ GA VN + +PL A G + +A L+E GA + VN
Sbjct: 259 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 318
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD--L 118
+G P+ A + +++ ++ + G + +T ++ A G++EV D +
Sbjct: 319 EGYTPLMEAAREGHEEMVALLLGQ-GANINAQTEETQETALTLA---CCGGFLEVADFLI 374
Query: 119 KTG-------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G TPL AA +G++++ K LL A+ G T L A G + A
Sbjct: 375 KAGADIELGCSTPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVA 433
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
+LL+ GAD ++ G+T L
Sbjct: 434 DVLLQAGADLEHESEGGRTPL 454
Score = 61.7 bits (143), Expect = 7e-09
Identities = 60/204 (29%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A ++ +V+ L+ H ADVN + G T L + G++ + + LLESGA + N
Sbjct: 126 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 185
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLK 119
+G P+ A S ++ + ++ E G N ++ ++ A G++E VR L
Sbjct: 186 NGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLA---CYKGHLEMVRFLL 241
Query: 120 TGG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G T L A G+++VA+ LL D A + +PL AA G
Sbjct: 242 EAGADQEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHV 300
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E AALL++ GA N G T L
Sbjct: 301 ELAALLIERGASLEEVNDEGYTPL 324
Score = 49.2 bits (112), Expect = 4e-05
Identities = 52/178 (29%), Positives = 77/178 (43%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 61 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 120
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A + +++ ++ K A+V+ S TG
Sbjct: 121 DITPLMAAANGGHVKIVKLLLAHK---------ADVNAQSS-----------------TG 154
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A GY+DV K LLE A + + G TPL A G E A LLL+ GA
Sbjct: 155 NTALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGA 211
Score = 46.4 bits (105), Expect = 3e-04
Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC L++ +FL+ GAD+ G + TPL A G + + +YLL +GA+V A G
Sbjct: 361 ACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATG 417
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D E + + G
Sbjct: 418 DTALTYACENGHTDVAD-VLLQAGADLE-------------------------HESEGGR 451
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA G++ + L+ + N + + + T L A G LLL GADP
Sbjct: 452 TPLMKAARAGHVCTVQFLISKGANVNRTTANNDH-TVLSLACAGGHLAVVELLLAHGADP 510
Query: 182 HLKNYSGQTCL 192
+ G T L
Sbjct: 511 THRLKDGSTML 521
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 389 MEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 448
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 449 GGRTPLMKAARAGHVCTVQFLIS-KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 507
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ V LL+
Sbjct: 508 ADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 538
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M AC+D ++++ L+ GA VN + +PL A G + +A L+E GA + VN
Sbjct: 439 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 498
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD--L 118
+G P+ A + +++ ++ + G + +T ++ A G++EV D +
Sbjct: 499 EGYTPLMEAAREGHEEMVALLLGQ-GANINAQTEETQETALTLA---CCGGFLEVADFLI 554
Query: 119 KTG-------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G TPL AA +G++++ K LL A+ G T L A G + A
Sbjct: 555 KAGADIELGCSTPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVA 613
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
+LL+ GAD ++ G+T L
Sbjct: 614 DVLLQAGADLEHESEGGRTPL 634
Score = 61.7 bits (143), Expect = 7e-09
Identities = 60/204 (29%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A ++ +V+ L+ H ADVN + G T L + G++ + + LLESGA + N
Sbjct: 306 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 365
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLK 119
+G P+ A S ++ + ++ E G N ++ ++ A G++E VR L
Sbjct: 366 NGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLA---CYKGHLEMVRFLL 421
Query: 120 TGG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G T L A G+++VA+ LL D A + +PL AA G
Sbjct: 422 EAGADQEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHV 480
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E AALL++ GA N G T L
Sbjct: 481 ELAALLIERGASLEEVNDEGYTPL 504
Score = 61.3 bits (142), Expect = 9e-09
Identities = 64/208 (30%), Positives = 97/208 (46%), Gaps = 25/208 (12%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++VE L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 1157 ACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1216
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 1217 LGISPLMLAAMNGHTAAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRTEVVSLL 1271
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 1272 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 1329
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCL 192
G + LL+ GA ++N G T L
Sbjct: 1330 KGHYKFCELLIGRGAHIDVRNKKGNTPL 1357
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/206 (27%), Positives = 99/206 (48%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V+ L+ GA + D +G+TPL A+ G + + LL++GAD+ A +
Sbjct: 1090 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 1149
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S ++++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 1150 KDTPLSLACSGGRQEVVELLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 1204
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G+ K LL D +D + ++ T L A G
Sbjct: 1205 AGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLL-DMGSDINAQIETNRNTALTLACFQG 1263
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 1264 RTEVVSLLLDRKANVEHRAKTGLTPL 1289
Score = 56.0 bits (129), Expect = 4e-07
Identities = 52/174 (29%), Positives = 75/174 (43%), Gaps = 25/174 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V L+ A+V G TPL AS G+ + R LL+ GADV A
Sbjct: 1259 ACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAP---- 1314
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
PV + A+ + +K + L+ +++VR+ K G
Sbjct: 1315 --PVPSSRDTALT-----------IAADKGHYKFCELLIGRG------AHIDVRN-KKGN 1354
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
TPL +AA G++DV + LL AD D D TPL AA G + L+K
Sbjct: 1355 TPLWLAANGGHLDVVQ-LLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1407
Score = 49.2 bits (112), Expect = 4e-05
Identities = 52/178 (29%), Positives = 77/178 (43%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A + +++ ++ K A+V+ S TG
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHK---------ADVNAQSS-----------------TG 334
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A GY+DV K LLE A + + G TPL A G E A LLL+ GA
Sbjct: 335 NTALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGA 391
Score = 46.4 bits (105), Expect = 3e-04
Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC L++ +FL+ GAD+ G + TPL A G + + +YLL +GA+V A G
Sbjct: 541 ACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATG 597
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D E + + G
Sbjct: 598 DTALTYACENGHTDVAD-VLLQAGADLE-------------------------HESEGGR 631
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA G++ + L+ + N + + + T L A G LLL GADP
Sbjct: 632 TPLMKAARAGHVCTVQFLISKGANVNRTTANNDH-TVLSLACAGGHLAVVELLLAHGADP 690
Query: 182 HLKNYSGQTCL 192
+ G T L
Sbjct: 691 THRLKDGSTML 701
Score = 42.7 bits (96), Expect = 0.003
Identities = 32/83 (38%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW-TPLHAAALWGQKEAA 171
+E RD K G TPL +AA G++ V + LL++ AD + TPL A G++E
Sbjct: 1109 IEHRD-KKGFTPLILAATAGHVGVVEILLDN-GADIEAQSERTKDTPLSLACSGGRQEVV 1166
Query: 172 ALLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 1167 ELLLARGANKEHRNVSDYTPLSL 1189
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 569 MEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 628
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 629 GGRTPLMKAARAGHVCTVQFLIS-KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 687
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ V LL+
Sbjct: 688 ADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 718
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined
breast cancer antigen NY-BR-16 protein.
Length = 1188
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M AC+D ++++ L+ GA VN + +PL A G + +A L+E GA + VN
Sbjct: 439 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 498
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD--L 118
+G P+ A + +++ ++ + G + +T ++ A G++EV D +
Sbjct: 499 EGYTPLMEAAREGHEEMVALLLGQ-GANINAQTEETQETALTLA---CCGGFLEVADFLI 554
Query: 119 KTG-------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G TPL AA +G++++ K LL A+ G T L A G + A
Sbjct: 555 KAGADIELGCSTPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVA 613
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
+LL+ GAD ++ G+T L
Sbjct: 614 DVLLQAGADLEHESEGGRTPL 634
Score = 61.7 bits (143), Expect = 7e-09
Identities = 60/204 (29%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A ++ +V+ L+ H ADVN + G T L + G++ + + LLESGA + N
Sbjct: 306 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 365
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLK 119
+G P+ A S ++ + ++ E G N ++ ++ A G++E VR L
Sbjct: 366 NGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLA---CYKGHLEMVRFLL 421
Query: 120 TGG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G T L A G+++VA+ LL D A + +PL AA G
Sbjct: 422 EAGADQEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHV 480
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E AALL++ GA N G T L
Sbjct: 481 ELAALLIERGASLEEVNDEGYTPL 504
Score = 49.2 bits (112), Expect = 4e-05
Identities = 52/178 (29%), Positives = 77/178 (43%), Gaps = 28/178 (15%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 63 EL-PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTG 121
++ P+ A + +++ ++ K A+V+ S TG
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHK---------ADVNAQSS-----------------TG 334
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A GY+DV K LLE A + + G TPL A G E A LLL+ GA
Sbjct: 335 NTALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGA 391
Score = 48.0 bits (109), Expect = 9e-05
Identities = 61/236 (25%), Positives = 97/236 (41%), Gaps = 41/236 (17%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC L++ +FL+ GAD+ G + TPL A G + + +YLL +GA+V A G
Sbjct: 541 ACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATG 597
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D E + + G
Sbjct: 598 DTALTYACENGHTDVAD-VLLQAGADLE-------------------------HESEGGR 631
Query: 123 TPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAALWGQKEAAA-LLLKFG 178
TPL AA G++ + L+ +C ++P + T L A A G A LLL G
Sbjct: 632 TPLMKAARAGHVCTVQFLISKGAECESEPQLI----MTILSALACAGGHLAVVELLLAHG 687
Query: 179 ADPHLKNYSGQTCLDLV----DPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
ADP + G T L S+ +L + + +L+PP H++ R
Sbjct: 688 ADPTHRLKDGSTMLIEAPKGGHTSVGCYLLDYPNNLLSAPPPDVTQLTPPSHDLNR 743
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 14/201 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M AC+D ++++ L+ GA VN + +PL A G + +A L+E GA + VN
Sbjct: 323 MEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVND 382
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRD--L 118
+G P+ A + +++ ++ + G + +T ++ A G++EV D +
Sbjct: 383 EGYTPLMEAAREGHEEMVALLLGQ-GANINAQTEETQETALTLA---CCGGFLEVADFLI 438
Query: 119 KTG-------GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
K G TPL AA +G++++ K LL A+ G T L A G + A
Sbjct: 439 KAGADIELGCSTPLMEAAQEGHLELVKYLLA-AGANVHATTATGDTALTYACENGHTDVA 497
Query: 172 ALLLKFGADPHLKNYSGQTCL 192
+LL+ GAD ++ G+T L
Sbjct: 498 DVLLQAGADLEHESEGGRTPL 518
Score = 61.7 bits (143), Expect = 7e-09
Identities = 60/204 (29%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+A ++ +V+ L+ H ADVN + G T L + G++ + + LLESGA + N
Sbjct: 190 MAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNE 249
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRDLK 119
+G P+ A S ++ + ++ E G N ++ ++ A G++E VR L
Sbjct: 250 NGHTPLMEAGSAGHVEVARLLL-ENGAGINTHSNEFKESALTLA---CYKGHLEMVRFLL 305
Query: 120 TGG-----------TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQK 168
G T L A G+++VA+ LL D A + +PL AA G
Sbjct: 306 EAGADQEHKTDEMHTALMEACMDGHVEVARLLL-DSGAQVNMPADSFESPLTLAACGGHV 364
Query: 169 EAAALLLKFGADPHLKNYSGQTCL 192
E AALL++ GA N G T L
Sbjct: 365 ELAALLIERGASLEEVNDEGYTPL 388
Score = 61.3 bits (142), Expect = 9e-09
Identities = 64/208 (30%), Positives = 97/208 (46%), Gaps = 25/208 (12%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++VE L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 1040 ACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 1099
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 1100 LGISPLMLAAMNGHTAAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRTEVVSLL 1154
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 1155 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 1212
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCL 192
G + LL+ GA ++N G T L
Sbjct: 1213 KGHYKFCELLIGRGAHIDVRNKKGNTPL 1240
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/206 (27%), Positives = 99/206 (48%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V+ L+ GA + D +G+TPL A+ G + + LL++GAD+ A +
Sbjct: 973 ACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERT 1032
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S ++++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 1033 KDTPLSLACSGGRQEVVELLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 1087
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G+ K LL D +D + ++ T L A G
Sbjct: 1088 AGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLL-DMGSDINAQIETNRNTALTLACFQG 1146
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 1147 RTEVVSLLLDRKANVEHRAKTGLTPL 1172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 52/174 (29%), Positives = 75/174 (43%), Gaps = 25/174 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V L+ A+V G TPL AS G+ + R LL+ GADV A
Sbjct: 1142 ACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAP---- 1197
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
PV + A+ + +K + L+ +++VR+ K G
Sbjct: 1198 --PVPSSRDTALT-----------IAADKGHYKFCELLIGRG------AHIDVRN-KKGN 1237
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
TPL +AA G++DV + LL AD D D TPL AA G + L+K
Sbjct: 1238 TPLWLAANGGHLDVVQ-LLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1290
Score = 48.0 bits (109), Expect = 9e-05
Identities = 51/177 (28%), Positives = 76/177 (42%), Gaps = 26/177 (14%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + +++ V L+ G VN EG + L S G+ +A+ LL A+V G
Sbjct: 125 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 184
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
++ +A ++ + K++ + A+V+ S TG
Sbjct: 185 DITSLMAAANGGHVKIVKLL--------LAHKADVNAQSS-----------------TGN 219
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
T L A A GY+DV K LLE A + + G TPL A G E A LLL+ GA
Sbjct: 220 TALTYACAGGYVDVVKVLLES-GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGA 275
Score = 46.4 bits (105), Expect = 3e-04
Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC L++ +FL+ GAD+ G + TPL A G + + +YLL +GA+V A G
Sbjct: 425 ACCGGFLEVADFLIKAGADIELGCS---TPLMEAAQEGHLELVKYLLAAGANVHATTATG 481
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ + A + D+ V+ + G D E + + G
Sbjct: 482 DTALTYACENGHTDVAD-VLLQAGADLE-------------------------HESEGGR 515
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
TPL AA G++ + L+ + N + + + T L A G LLL GADP
Sbjct: 516 TPLMKAARAGHVCTVQFLISKGANVNRTTANNDH-TVLSLACAGGHLAVVELLLAHGADP 574
Query: 182 HLKNYSGQTCL 192
+ G T L
Sbjct: 575 THRLKDGSTML 585
Score = 42.7 bits (96), Expect = 0.003
Identities = 32/83 (38%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW-TPLHAAALWGQKEAA 171
+E RD K G TPL +AA G++ V + LL++ AD + TPL A G++E
Sbjct: 992 IEHRD-KKGFTPLILAATAGHVGVVEILLDN-GADIEAQSERTKDTPLSLACSGGRQEVV 1049
Query: 172 ALLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 1050 ELLLARGANKEHRNVSDYTPLSL 1072
Score = 41.5 bits (93), Expect = 0.008
Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 10/151 (6%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+ +
Sbjct: 453 MEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESE 512
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR--------EWAL-HG 111
G P+ A +Q +I KG + ++ T++S A E L HG
Sbjct: 513 GGRTPLMKAARAGHVCTVQFLIS-KGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHG 571
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLE 142
LK G T L AA G+ V LL+
Sbjct: 572 ADPTHRLKDGSTMLIEAAKGGHTSVVCYLLD 602
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 66.9 bits (156), Expect = 2e-10
Identities = 54/173 (31%), Positives = 80/173 (46%), Gaps = 12/173 (6%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVD-- 88
TPLH A G+ S+A+ L E+G +V N +GE P+ A + D+++ + E G D
Sbjct: 481 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVE-CLAEHGADLN 539
Query: 89 -CEKSRNAEVDTL-----MSDAREWALHG-YVEVRDLKTGGTPLHVAAAKGYIDVAKTLL 141
C+K + + M + G +V+ +D + G TPLHVA G + + L
Sbjct: 540 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQD-RHGNTPLHVACKDGNMPIVVALC 598
Query: 142 EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
E N + D + G TPLH AA G + L GA G+T DL
Sbjct: 599 E-ANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDL 650
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/200 (28%), Positives = 87/200 (43%), Gaps = 13/200 (6%)
Query: 6 DDNLDMVEFLV--THGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE 63
DDN+ ++ L+ DVN+ + G PL A CG I I + L++ G+ + + G
Sbjct: 354 DDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGS 413
Query: 64 LPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLM------SDARE--WALHGYVEV 115
V A D L+ + + K K ++ E+ + +D + A + +
Sbjct: 414 NAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPI 473
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
K TPLH AA GY VAK L E CN + + EG TPL A+ G + L
Sbjct: 474 SRTKEEETPLHCAAWHGYYSVAKALCEAGCNV--NIKNREGETPLLTASARGYHDIVECL 531
Query: 175 LKFGADPHLKNYSGQTCLDL 194
+ GAD + + G L L
Sbjct: 532 AEHGADLNACDKDGHIALHL 551
Score = 50.4 bits (115), Expect = 2e-05
Identities = 25/70 (35%), Positives = 38/70 (54%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D N+ +V L +++ + G TPLH A+ G + + RYL GA V A+ DG
Sbjct: 585 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 644
Query: 63 ELPVDIAESD 72
+ D+A S+
Sbjct: 645 KTAEDLARSE 654
Score = 45.6 bits (103), Expect = 5e-04
Identities = 45/173 (26%), Positives = 68/173 (39%), Gaps = 27/173 (15%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
D+VE L HGAD+N D +G LH + + + LL G V + G P+ +A
Sbjct: 526 DIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA 585
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAA 129
D ++ + CE + N ++ K G TPLH+AA
Sbjct: 586 CKDGNMPIVVAL-------CEANCNLDISN-------------------KYGRTPLHLAA 619
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
G +DV + L A + + +G T A + A LL + D H
Sbjct: 620 NNGILDVVRYLCL-MGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTH 671
>AK091782-1|BAC03746.1| 596|Homo sapiens protein ( Homo sapiens
cDNA FLJ34463 fis, clone HLUNG2003042, moderately
similar to Mus musculus mRNA for MAIL. ).
Length = 596
Score = 66.9 bits (156), Expect = 2e-10
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGA-------DVAAVNYDGE 63
+V+ LV GA VN D G TPLH A G + + ++ GA D+ A NYDG
Sbjct: 373 IVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQ-AIQKGAVGSNQFVDLEATNYDGL 431
Query: 64 LPVDIA--ESDAMADLLQKVIDEKGVDCEK---SRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A +A+ LQ+ + ++ + VDT+ + A VE +D
Sbjct: 432 TPLHCAVIAHNAVFHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAA---VEAKDR 488
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLE--DCNADPDCVDYEGWTPLHAAA----LWGQKEAAA 172
K+G T LH+AA + +++ + LE C + + Y G T LH AA Q +A
Sbjct: 489 KSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVR 548
Query: 173 LLLKFGADPHLKNYSGQTCLDLV 195
LL++ GADP +N + + LV
Sbjct: 549 LLMRKGADPSTRNLENEQPVHLV 571
>AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated
transcript 8 BAT8 isoform a variant protein.
Length = 1031
Score = 66.9 bits (156), Expect = 2e-10
Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 21/203 (10%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESG-ADVAAVN 59
M A ++++L++ ++V G V + +G T LH A G + + LL +G DV A +
Sbjct: 537 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQD 596
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
G P+ A ++++ ++ +R A+V TL + E R ++
Sbjct: 597 SGGWTPIIWAAEHKHIEVIRMLL---------TRGADV-TLTDNVSE---------RLVE 637
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
LH A+ G +A+ LL + D V+Y G TPLH AA + L L GA
Sbjct: 638 EENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGA 696
Query: 180 DPHLKNYSGQTCLDLVDPSISSW 202
+P L+N G T DL W
Sbjct: 697 NPELRNKEGDTAWDLTPERSDVW 719
Score = 48.8 bits (111), Expect = 5e-05
Identities = 52/181 (28%), Positives = 78/181 (43%), Gaps = 20/181 (11%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 501 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 558
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 559 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 618
Query: 141 LEDCNADPDCVD-------YEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLD 193
L AD D E LH A+ G A +LL D H NY G T L
Sbjct: 619 LTR-GADVTLTDNVSERLVEEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLH 677
Query: 194 L 194
+
Sbjct: 678 I 678
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 495 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 553
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 554 RGGCVYSKEEDGSTCL 569
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 10/182 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N +++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G
Sbjct: 82 ATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAG 141
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
+ +A ++ + +V+ G + NA L AR L + V
Sbjct: 142 NTALHLACQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 116 RDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ + G T LHVAAA + VAK LLE AD V+ G TPL A E A LL
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLL 259
Query: 175 LK 176
K
Sbjct: 260 TK 261
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE-----LPVDIA 69
L+ GA V G TPLH A+ G + + + LL++G D+ V DG+ +
Sbjct: 29 LINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDL-DVQDDGDQTALHRATVVG 86
Query: 70 ESDAMADLLQK--VIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
++ +A L+ + +D + D + A A+ G + K G T LH
Sbjct: 87 NTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALH 146
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
+A + + LL + D + G T LH AA + LLL H KN
Sbjct: 147 LACQNSHSQSTRVLLL-AGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 187 SGQTCL 192
+G T L
Sbjct: 206 AGDTAL 211
Score = 43.2 bits (97), Expect = 0.003
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LH A G ++ L+ E C D D +G T LH A+ G ++A LL+K GA+
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLIKAGANV 134
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
KN +G T L L + S L A R +
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRAD 168
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 10/182 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N +++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G
Sbjct: 82 ATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAG 141
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
+ +A ++ + +V+ G + NA L AR L + V
Sbjct: 142 NTALHLACQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 116 RDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ + G T LHVAAA + VAK LLE AD V+ G TPL A E A LL
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLL 259
Query: 175 LK 176
K
Sbjct: 260 TK 261
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE-----LPVDIA 69
L+ GA V G TPLH A+ G + + + LL++G D+ V DG+ +
Sbjct: 29 LINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDL-DVQDDGDQTALHRATVVG 86
Query: 70 ESDAMADLLQK--VIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
++ +A L+ + +D + D + A A+ G + K G T LH
Sbjct: 87 NTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALH 146
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
+A + + LL + D + G T LH AA + LLL H KN
Sbjct: 147 LACQNSHSQSTRVLLL-AGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 187 SGQTCL 192
+G T L
Sbjct: 206 AGDTAL 211
Score = 43.2 bits (97), Expect = 0.003
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LH A G ++ L+ E C D D +G T LH A+ G ++A LL+K GA+
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLIKAGANV 134
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
KN +G T L L + S L A R +
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRAD 168
>DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein.
Length = 871
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+V FL+ GA VN ++ GW+ L A G +S+A LL+ GADV A N G + +A
Sbjct: 93 LVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVAS 152
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAA 130
++ K++ E G A VD + L G RD T L A
Sbjct: 153 RGGHLGVV-KLLLEAG--------AFVDHHHPSGEQLGLGG---SRDEPLDITALMAAIQ 200
Query: 131 KGYIDVAKTLLEDCNADPD-CVDYEGWTPLHAAALWGQKEAAALLLKFGADPH----LKN 185
G+ V + L+E ADP+ GW+PL AAL G+ A L++ GA+P L+
Sbjct: 201 HGHEAVVRLLME-WGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEK 259
Query: 186 YSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
+ + LD + +L+ P+ +R
Sbjct: 260 TAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRR 293
Score = 61.7 bits (143), Expect = 7e-09
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 14/197 (7%)
Query: 11 MVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGAD---VAAVNYDG-ELP 65
+V L+ GAD N GW+PL A G + +A+ L+E GA+ ++ + E+
Sbjct: 206 VVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEKTAFEVA 265
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDA-----REWALHGYVEVRDLK- 119
+D D + D L + + E+ R ++ + +E A V +
Sbjct: 266 LDCKHRD-LVDYLDPLTTVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPSHVNLVNG 324
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVD-YEGWTPLHAAALWGQKEAAALLLKFG 178
G TPL +AA G + + + L+E +AD D D GWT L A G KE LL G
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVER-HADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQG 383
Query: 179 ADPHLKNYSGQTCLDLV 195
AD L+ +G T DLV
Sbjct: 384 ADVTLRAKNGYTAFDLV 400
Score = 41.9 bits (94), Expect = 0.006
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDN-EGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A + L +V+ LV ADV++ D+ GWT L G I +YLL GADV
Sbjct: 331 MLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Query: 60 YDGELPVDI 68
+G D+
Sbjct: 391 KNGYTAFDL 399
Score = 39.9 bits (89), Expect = 0.025
Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A ++ + L+ HGADVN + G + L + G + + + LLE+GA V +
Sbjct: 116 MQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHP 175
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
GE D D+ + + A V LM EW R +
Sbjct: 176 SGEQLGLGGSRDEPLDITALM-----AAIQHGHEAVVRLLM----EWGADPNHAARTV-- 224
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
G +PL +AA G + VA+ L+E A+PD
Sbjct: 225 GWSPLMLAALTGRLGVAQQLVEK-GANPD 252
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 10/182 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N +++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G
Sbjct: 82 ATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAG 141
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
+ +A ++ + +V+ G + NA L AR L + V
Sbjct: 142 NTALHLACQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 200
Query: 116 RDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ + G T LHVAAA + VAK LLE AD V+ G TPL A E A LL
Sbjct: 201 HEKNQAGDTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLL 259
Query: 175 LK 176
K
Sbjct: 260 TK 261
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE-----LPVDIA 69
L+ GA V G TPLH A+ G + + + LL++G D+ V DG+ +
Sbjct: 29 LINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDL-DVQDDGDQTALHRATVVG 86
Query: 70 ESDAMADLLQK--VIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
++ +A L+ + +D + D + A A+ G + K G T LH
Sbjct: 87 NTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALH 146
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
+A + + LL + D + G T LH AA + LLL H KN
Sbjct: 147 LACQNSHSQSTRVLLL-AGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 187 SGQTCL 192
+G T L
Sbjct: 206 AGDTAL 211
Score = 42.7 bits (96), Expect = 0.003
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LH A G ++ L+ E C D D +G T LH A+ G ++A LL+K GA+
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLVKAGANV 134
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
KN +G T L L + S L A R +
Sbjct: 135 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRAD 168
>BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 29
protein.
Length = 301
Score = 66.1 bits (154), Expect = 3e-10
Identities = 60/188 (31%), Positives = 90/188 (47%), Gaps = 30/188 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++ +VE L+ HGA+++ +G T L A G++ + R LL SGA V DG P+
Sbjct: 124 HMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLW 183
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
IA ++++ +V+ +G D + +RN G T L
Sbjct: 184 IASQMGHSEVV-RVMLLRGADRDAARN-------------------------DGTTALLK 217
Query: 128 AAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
AA KGY DV K LL+ P + G + LHAA L G + ALLL+ GADP L+N
Sbjct: 218 AANKGYNDVIKELLK---FSPTLGILKNGTSALHAAVLSGNIKTVALLLEAGADPSLRNK 274
Query: 187 SGQTCLDL 194
+ + +L
Sbjct: 275 ANELPAEL 282
Score = 53.6 bits (123), Expect = 2e-06
Identities = 54/194 (27%), Positives = 80/194 (41%), Gaps = 11/194 (5%)
Query: 8 NLDMVEFLVTHG-ADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
NL +++ L+ G DV+ D+ G T L A G I R L+ GAD+ G +
Sbjct: 24 NLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRESGTTAL 83
Query: 67 DIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRD-L 118
A D++ + + G E E L++ ++ E L + D L
Sbjct: 84 FFAAQQGHNDVV-RFLFGFGASTEFRTKDEGTALLAASQYGHMQVVETLLKHGANIHDQL 142
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
G T L +AA GY+DV + LL A + +G PL A+ G E ++L G
Sbjct: 143 YDGATALFLAAQGGYLDVIRLLLAS-GAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRG 201
Query: 179 ADPHLKNYSGQTCL 192
AD G T L
Sbjct: 202 ADRDAARNDGTTAL 215
Score = 40.3 bits (90), Expect = 0.019
Identities = 25/65 (38%), Positives = 32/65 (49%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
AA +G + + K LL D DC D G T L AA G + L+ GAD +L+ S
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78
Query: 188 GQTCL 192
G T L
Sbjct: 79 GTTAL 83
Score = 35.5 bits (78), Expect = 0.53
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 29 GWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQ 79
G + LHA G I LLE+GAD + N ELP ++ +++ + LL+
Sbjct: 243 GTSALHAAVLSGNIKTVALLLEAGADPSLRNKANELPAELTKNERILRLLR 293
>AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+V FL+ GA VN ++ GW+ L A G +S+A LL+ GADV A N G + +A
Sbjct: 93 LVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVAS 152
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAA 130
++ K++ E G A VD + L G RD T L A
Sbjct: 153 RGGHLGVV-KLLLEAG--------AFVDHHHPSGEQLGLGG---SRDEPLDITALMAAIQ 200
Query: 131 KGYIDVAKTLLEDCNADPD-CVDYEGWTPLHAAALWGQKEAAALLLKFGADPH----LKN 185
G+ V + L+E ADP+ GW+PL AAL G+ A L++ GA+P L+
Sbjct: 201 HGHEAVVRLLME-WGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEK 259
Query: 186 YSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
+ + LD + +L+ P+ +R
Sbjct: 260 TAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRR 293
Score = 61.7 bits (143), Expect = 7e-09
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 14/197 (7%)
Query: 11 MVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGAD---VAAVNYDG-ELP 65
+V L+ GAD N GW+PL A G + +A+ L+E GA+ ++ + E+
Sbjct: 206 VVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEKTAFEVA 265
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDA-----REWALHGYVEVRDLK- 119
+D D + D L + + E+ R ++ + +E A V +
Sbjct: 266 LDCKHRD-LVDYLDPLTTVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPSHVNLVNG 324
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVD-YEGWTPLHAAALWGQKEAAALLLKFG 178
G TPL +AA G + + + L+E +AD D D GWT L A G KE LL G
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVER-HADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQG 383
Query: 179 ADPHLKNYSGQTCLDLV 195
AD L+ +G T DLV
Sbjct: 384 ADVTLRAKNGYTAFDLV 400
Score = 41.9 bits (94), Expect = 0.006
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDN-EGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A + L +V+ LV ADV++ D+ GWT L G I +YLL GADV
Sbjct: 331 MLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Query: 60 YDGELPVDI 68
+G D+
Sbjct: 391 KNGYTAFDL 399
Score = 39.9 bits (89), Expect = 0.025
Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A ++ + L+ HGADVN + G + L + G + + + LLE+GA V +
Sbjct: 116 MQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHP 175
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
GE D D+ + + A V LM EW R +
Sbjct: 176 SGEQLGLGGSRDEPLDITALM-----AAIQHGHEAVVRLLM----EWGADPNHAARTV-- 224
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
G +PL +AA G + VA+ L+E A+PD
Sbjct: 225 GWSPLMLAALTGRLGVAQQLVEK-GANPD 252
>AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/214 (29%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 11 MVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAE 70
+V FL+ GA VN ++ GW+ L A G +S+A LL+ GADV A N G + +A
Sbjct: 93 LVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVAS 152
Query: 71 SDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAA 130
++ K++ E G A VD + L G RD T L A
Sbjct: 153 RGGHLGVV-KLLLEAG--------AFVDHHHPSGEQLGLGG---SRDEPLDITALMAAIQ 200
Query: 131 KGYIDVAKTLLEDCNADPD-CVDYEGWTPLHAAALWGQKEAAALLLKFGADPH----LKN 185
G+ V + L+E ADP+ GW+PL AAL G+ A L++ GA+P L+
Sbjct: 201 HGHEAVVRLLME-WGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEK 259
Query: 186 YSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKR 219
+ + LD + +L+ P+ +R
Sbjct: 260 TAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRR 293
Score = 61.7 bits (143), Expect = 7e-09
Identities = 59/197 (29%), Positives = 89/197 (45%), Gaps = 14/197 (7%)
Query: 11 MVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGAD---VAAVNYDG-ELP 65
+V L+ GAD N GW+PL A G + +A+ L+E GA+ ++ + E+
Sbjct: 206 VVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSVLEKTAFEVA 265
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDA-----REWALHGYVEVRDLK- 119
+D D + D L + + E+ R ++ + +E A V +
Sbjct: 266 LDCKHRD-LVDYLDPLTTVRPKTDEEKRRPDIFHALKMGNFQLVKEIADEDPSHVNLVNG 324
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVD-YEGWTPLHAAALWGQKEAAALLLKFG 178
G TPL +AA G + + + L+E +AD D D GWT L A G KE LL G
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVER-HADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQG 383
Query: 179 ADPHLKNYSGQTCLDLV 195
AD L+ +G T DLV
Sbjct: 384 ADVTLRAKNGYTAFDLV 400
Score = 41.9 bits (94), Expect = 0.006
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDN-EGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A + L +V+ LV ADV++ D+ GWT L G I +YLL GADV
Sbjct: 331 MLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Query: 60 YDGELPVDI 68
+G D+
Sbjct: 391 KNGYTAFDL 399
Score = 39.9 bits (89), Expect = 0.025
Identities = 42/149 (28%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A ++ + L+ HGADVN + G + L + G + + + LLE+GA V +
Sbjct: 116 MQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHP 175
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKT 120
GE D D+ + + A V LM EW R +
Sbjct: 176 SGEQLGLGGSRDEPLDITALM-----AAIQHGHEAVVRLLM----EWGADPNHAARTV-- 224
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPD 149
G +PL +AA G + VA+ L+E A+PD
Sbjct: 225 GWSPLMLAALTGRLGVAQQLVEK-GANPD 252
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 10/182 (5%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + N +++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G
Sbjct: 83 ATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAG 142
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEV 115
+ +A ++ + +V+ G + NA L AR L + V
Sbjct: 143 NTALHLACQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSV 201
Query: 116 RDL-KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ + G T LHVAAA + VAK LLE AD V+ G TPL A E A LL
Sbjct: 202 HEKNQAGDTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLL 260
Query: 175 LK 176
K
Sbjct: 261 TK 262
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 11/186 (5%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGE-----LPVDIA 69
L+ GA V G TPLH A+ G + + + LL++G D+ V DG+ +
Sbjct: 30 LINKGARV-AVTKHGRTPLHLAANKGHLPVVQILLKAGCDL-DVQDDGDQTALHRATVVG 87
Query: 70 ESDAMADLLQK--VIDEKGVDCEKS-RNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLH 126
++ +A L+ + +D + D + A A+ G + K G T LH
Sbjct: 88 NTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALH 147
Query: 127 VAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNY 186
+A + + LL + D + G T LH AA + LLL H KN
Sbjct: 148 LACQNSHSQSTRVLLL-AGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQ 206
Query: 187 SGQTCL 192
+G T L
Sbjct: 207 AGDTAL 212
Score = 42.7 bits (96), Expect = 0.003
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 123 TPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
T LH A G ++ L+ E C D D +G T LH A+ G ++A LL+K GA+
Sbjct: 78 TALHRATVVGNTEIIAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLVKAGANV 135
Query: 182 HLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN 215
KN +G T L L + S L A R +
Sbjct: 136 LAKNKAGNTALHLACQNSHSQSTRVLLLAGSRAD 169
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 488 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 547
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 548 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 602
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 603 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 661
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 662 LSRGANPELRNKEGDTAWDLTPERSDVW 689
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 535
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 536 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 595
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 596 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 648
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 472 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 530
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 531 RGGCVYSKEEDGSTCL 546
>DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein.
Length = 593
Score = 65.7 bits (153), Expect = 4e-10
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 13/196 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
++ ++ G D + D W P+H A G + + L++ G + V+Y+G LPV +A
Sbjct: 233 LQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAM 292
Query: 72 DAMADLLQKVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVE-----------VRDL 118
+ + ++ + K+ N + ++ A+ + ++ + D
Sbjct: 293 EGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQ 352
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
+T P HVAA KG + + K L+ED + + G TP+H AA G E L+K G
Sbjct: 353 ETLAFPGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMG 412
Query: 179 ADPHLKNYSGQTCLDL 194
AD ++ N +G+ D+
Sbjct: 413 ADSNITNKAGERPSDV 428
Score = 51.6 bits (118), Expect = 8e-06
Identities = 52/192 (27%), Positives = 86/192 (44%), Gaps = 33/192 (17%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L+ + +L+ HGAD+ GWT H A G + + L+ +GA++ A + G P+
Sbjct: 163 SLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLH 222
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
+A + + LQ ++ + VD ++D REW P+H
Sbjct: 223 LAATHGHSFTLQIML-----------RSGVDPSVTDKREW---------------RPVHY 256
Query: 128 AAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK--FGADPHLK 184
AA G + + L++ C+ + VDY G P+H AA+ G L+ A LK
Sbjct: 257 AAFHGRLGCLQLLVKWGCSIED--VDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLK 314
Query: 185 --NYSGQTCLDL 194
N +G+ LDL
Sbjct: 315 AFNDNGENVLDL 326
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 5/118 (4%)
Query: 3 ACIDDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A +L M++ LV G ++N + G TP+H A G I ++L++ GAD N
Sbjct: 362 AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKA 421
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
GE P D+A+ A ++ + + + D + E+D +D + + HG D K
Sbjct: 422 GERPSDVAKRFAHLAAVKLLEELQKYDIDDEN--EIDE--NDVKYFIRHGVEGSTDAK 475
Score = 37.9 bits (84), Expect = 0.099
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ LL AD V GWT H AA+ GQ L+ GA+
Sbjct: 153 TPLHWAAHSGSLECLHWLLWH-GADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLT 211
Query: 183 LKNYSGQTCLDL 194
++ G T L L
Sbjct: 212 AQDDRGCTPLHL 223
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 409 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 468
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 469 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 523
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 524 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 582
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 583 LSRGANPELRNKEGDTAWDLTPERSDVW 610
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 399 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 456
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 457 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 516
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 517 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 569
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 393 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 451
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 452 RGGCVYSKEEDGSTCL 467
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 375 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 434
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 435 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 489
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 490 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 548
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 549 LSRGANPELRNKEGDTAWDLTPERSDVW 576
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 365 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 422
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 423 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 482
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 483 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 535
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 359 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 417
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 418 RGGCVYSKEEDGSTCL 433
>BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 297
Score = 65.7 bits (153), Expect = 4e-10
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 22/216 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 14 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 73
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WAL-HGYVEV-RD 117
A +++ ++ VD +L S ++ WA H ++EV R
Sbjct: 74 HAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAEHKHIEVIRM 133
Query: 118 LKTGGTP-----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
L T G LH A+ G +A+ LL + D V+Y G TPLH AA
Sbjct: 134 LLTRGADVTLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARES 192
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSW 202
+ L L GA+P L+N G T DL W
Sbjct: 193 YHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVW 228
Score = 47.6 bits (108), Expect = 1e-04
Identities = 48/181 (26%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 4 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 61
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDV-AKTLLEDCNADPD 149
S+ + T LH ++ +L+ + + + G +DV A+ L +
Sbjct: 62 YSKEEDGST--------CLHHAAKIGNLEM----VSLLLSTGQVDVNAQGQLPPPSLPSH 109
Query: 150 CVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALK 209
D GWTP+ AA E +LL GAD L + CL + S+ + E L
Sbjct: 110 PQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 169
Query: 210 A 210
A
Sbjct: 170 A 170
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 685 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 744
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 745 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 799
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 800 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 858
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 859 LSRGANPELRNKEGDTAWDLTPERSDVW 886
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 675 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 732
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 733 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 792
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 793 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 845
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 669 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 727
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 728 RGGCVYSKEEDGSTCL 743
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 488 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 547
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 548 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 602
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 603 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 661
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 662 LSRGANPELRNKEGDTAWDLTPERSDVW 689
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 535
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 536 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 595
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 596 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 648
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 472 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 530
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 531 RGGCVYSKEEDGSTCL 546
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 696 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 755
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 756 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 810
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 811 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 869
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 870 LSRGANPELRNKEGDTAWDLTPERSDVW 897
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 686 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 743
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 744 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 803
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 804 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 856
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 680 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 738
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 739 RGGCVYSKEEDGSTCL 754
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 530 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 589
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 590 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 644
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 645 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 703
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 704 LSRGANPELRNKEGDTAWDLTPERSDVW 731
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 520 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 577
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 578 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 637
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 638 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 690
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 514 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 572
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 573 RGGCVYSKEEDGSTCL 588
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 488 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 547
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 548 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 602
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 603 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 661
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 662 LSRGANPELRNKEGDTAWDLTPERSDVW 689
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 535
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 536 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 595
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 596 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 648
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 472 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 530
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 531 RGGCVYSKEEDGSTCL 546
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1210
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 697 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 756
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 757 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 811
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 812 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 870
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 871 LSRGANPELRNKEGDTAWDLTPERSDVW 898
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 744
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 745 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 805 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 857
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 681 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 739
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 740 RGGCVYSKEEDGSTCL 755
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1176
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 663 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 722
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 723 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 777
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 778 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 836
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 837 LSRGANPELRNKEGDTAWDLTPERSDVW 864
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 710
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 711 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 770
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 771 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 823
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 647 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 705
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 706 RGGCVYSKEEDGSTCL 721
>AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 697 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 756
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 757 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 811
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 812 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 870
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 871 LSRGANPELRNKEGDTAWDLTPERSDVW 898
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 744
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 745 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 805 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 857
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 681 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 739
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 740 RGGCVYSKEEDGSTCL 755
>AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 663 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 722
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 723 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 777
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 778 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 836
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 837 LSRGANPELRNKEGDTAWDLTPERSDVW 864
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 710
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 711 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 770
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 771 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 823
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 647 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 705
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 706 RGGCVYSKEEDGSTCL 721
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 754 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 813
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 814 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 868
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 869 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 927
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 928 LSRGANPELRNKEGDTAWDLTPERSDVW 955
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 801
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 802 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 861
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 862 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 914
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 738 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 796
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 797 RGGCVYSKEEDGSTCL 812
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 720 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 779
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 780 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 834
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 835 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 893
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 894 LSRGANPELRNKEGDTAWDLTPERSDVW 921
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 767
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 768 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 827
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 828 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 880
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 704 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 762
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 763 RGGCVYSKEEDGSTCL 778
>AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 297
Score = 65.7 bits (153), Expect = 4e-10
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 22/216 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 14 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 73
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WAL-HGYVEV-RD 117
A +++ ++ VD +L S ++ WA H ++EV R
Sbjct: 74 HAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAEHKHIEVIRM 133
Query: 118 LKTGGTP-----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
L T G LH A+ G +A+ LL + D V+Y G TPLH AA
Sbjct: 134 LLTRGADVTLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARES 192
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSW 202
+ L L GA+P L+N G T DL W
Sbjct: 193 YHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVW 228
Score = 47.6 bits (108), Expect = 1e-04
Identities = 48/181 (26%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 4 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 61
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDV-AKTLLEDCNADPD 149
S+ + T LH ++ +L+ + + + G +DV A+ L +
Sbjct: 62 YSKEEDGST--------CLHHAAKIGNLEM----VSLLLSTGQVDVNAQGQLPPPSLPSH 109
Query: 150 CVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALK 209
D GWTP+ AA E +LL GAD L + CL + S+ + E L
Sbjct: 110 PQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 169
Query: 210 A 210
A
Sbjct: 170 A 170
>AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 663 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 722
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 723 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 777
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 778 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 836
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 837 LSRGANPELRNKEGDTAWDLTPERSDVW 864
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 710
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 711 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 770
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 771 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 823
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 647 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 705
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 706 RGGCVYSKEEDGSTCL 721
>AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 697 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 756
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 757 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 811
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 812 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 870
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 871 LSRGANPELRNKEGDTAWDLTPERSDVW 898
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 744
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 745 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 805 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 857
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 681 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 739
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 740 RGGCVYSKEEDGSTCL 755
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 754 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 813
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 814 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 868
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 869 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 927
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 928 LSRGANPELRNKEGDTAWDLTPERSDVW 955
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 801
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 802 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 861
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 862 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 914
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 738 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 796
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 797 RGGCVYSKEEDGSTCL 812
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 720 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 779
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 780 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 834
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 835 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 893
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 894 LSRGANPELRNKEGDTAWDLTPERSDVW 921
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 767
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 768 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 827
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 828 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 880
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 704 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 762
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 763 RGGCVYSKEEDGSTCL 778
>AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 297
Score = 65.7 bits (153), Expect = 4e-10
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 22/216 (10%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 14 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 73
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE--------WAL-HGYVEV-RD 117
A +++ ++ VD +L S ++ WA H ++EV R
Sbjct: 74 HAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAEHKHIEVIRM 133
Query: 118 LKTGGTP-----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
L T G LH A+ G +A+ LL + D V+Y G TPLH AA
Sbjct: 134 LLTRGADVTLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARES 192
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSW 202
+ L L GA+P L+N G T DL W
Sbjct: 193 YHDCVLLFLSRGANPELRNKEGDTAWDLTPERSDVW 228
Score = 47.6 bits (108), Expect = 1e-04
Identities = 48/181 (26%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 4 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 61
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDV-AKTLLEDCNADPD 149
S+ + T LH ++ +L+ + + + G +DV A+ L +
Sbjct: 62 YSKEEDGST--------CLHHAAKIGNLEM----VSLLLSTGQVDVNAQGQLPPPSLPSH 109
Query: 150 CVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALK 209
D GWTP+ AA E +LL GAD L + CL + S+ + E L
Sbjct: 110 PQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLN 169
Query: 210 A 210
A
Sbjct: 170 A 170
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 697 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 756
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 757 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 811
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 812 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 870
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 871 LSRGANPELRNKEGDTAWDLTPERSDVW 898
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 744
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 745 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 805 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 857
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 681 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 739
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 740 RGGCVYSKEEDGSTCL 755
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
++++ L+ GA++N D + TPL + +ARY+++ G V + DG +
Sbjct: 488 SVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLH 547
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWAL-HGYVEV-RDLKTGGTP- 124
A +++ ++ VD + ++ WA H ++EV R L T G
Sbjct: 548 HAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPII-----WAAEHKHIEVIRMLLTRGADV 602
Query: 125 ----------LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
LH A+ G +A+ LL + D V+Y G TPLH AA + L
Sbjct: 603 TLTDNEENICLHWASFTGSAAIAEVLL-NARCDLHAVNYHGDTPLHIAARESYHDCVLLF 661
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSW 202
L GA+P L+N G T DL W
Sbjct: 662 LSRGANPELRNKEGDTAWDLTPERSDVW 689
Score = 58.0 bits (134), Expect = 9e-08
Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
TPLHA A G + I LL++GA++ AV+ P+ A + ++ + ++ G C
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGG--CV 535
Query: 91 KSRNAEVDTLMSDARE---------WALHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTL 140
S+ + T + A + G V+V +GG TP+ AA +I+V + L
Sbjct: 536 YSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 595
Query: 141 LEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
L AD D E LH A+ G A +LL D H NY G T L +
Sbjct: 596 LTR-GADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHI 648
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D ++ TPLH AA KG +++ LL+ A+ + VD + TPL A + E A +++
Sbjct: 472 DQQSKRTPLHAAAQKGSVEICHVLLQ-AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 530
Query: 177 FGADPHLKNYSGQTCL 192
G + K G TCL
Sbjct: 531 RGGCVYSKEEDGSTCL 546
>AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens
cDNA FLJ37874 fis, clone BRSSN2018731, weakly similar to
ANKYRIN 1. ).
Length = 389
Score = 65.3 bits (152), Expect = 6e-10
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 13/196 (6%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
++ ++ G D + D W P+H A G + + L++ G + V+Y+G LPV +A
Sbjct: 114 LQIMLRSGVDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCGIEDVDYNGNLPVHLAAM 173
Query: 72 DAMADLLQKVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVE-----------VRDL 118
+ + ++ + K+ N + ++ A+ + ++ + D
Sbjct: 174 EGHLHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQ 233
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFG 178
+T P HVAA KG + + K L+ED + + G TP+H AA G E L+K G
Sbjct: 234 ETLAFPGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMG 293
Query: 179 ADPHLKNYSGQTCLDL 194
AD ++ N +G+ D+
Sbjct: 294 ADSNITNKAGERPSDV 309
Score = 48.8 bits (111), Expect = 5e-05
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 33/188 (17%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAES 71
+ +L+ HGAD+ GWT H A G + + L+ +GA++ A + G P+ +A +
Sbjct: 48 LHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLHLAAT 107
Query: 72 DAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAK 131
+ LQ ++ + VD ++D REW P+H AA
Sbjct: 108 HGHSFTLQIML-----------RSGVDPSVTDKREW---------------RPVHYAAFH 141
Query: 132 GYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK--FGADPHLK--NY 186
G + + L++ C + VDY G P+H AA+ G L+ A LK N
Sbjct: 142 GRLGCLQLLVKWGCGIED--VDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFND 199
Query: 187 SGQTCLDL 194
+G+ LDL
Sbjct: 200 NGENVLDL 207
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 5/118 (4%)
Query: 3 ACIDDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A +L M++ LV G ++N + G TP+H A G I ++L++ GAD N
Sbjct: 243 AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKA 302
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
GE P D+A+ A ++ + + + D + E+D +D + + HG D K
Sbjct: 303 GERPSDVAKRFAHLAAVKLLEELQKYDIDDEN--EIDE--NDVKYFIRHGVEGSTDAK 356
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 64.9 bits (151), Expect = 8e-10
Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 12/191 (6%)
Query: 6 DDNLDMVEFLVTHGADVN-RGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGEL 64
D + ++ L+ GA + R D G T LH A A+ LL++GAD A ++ G
Sbjct: 1815 DTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRT 1874
Query: 65 PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-----RDL- 118
P+ A + + Q +I + D + +R A+ T + A A+ G VE D+
Sbjct: 1875 PLHTAVTADAQGVFQILIRNRSTDLD-ARMADGSTALILAARLAVEGMVEELIASHADVN 1933
Query: 119 ---KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
+ G + LH AAA ++ LL++ A+ D D + TPL AA G EAA LLL
Sbjct: 1934 AVDELGKSALHWAAAVNNVEATLALLKN-GANKDMQDSKEETPLFLAAREGSYEAAKLLL 1992
Query: 176 KFGADPHLKNY 186
A+ + ++
Sbjct: 1993 DHFANREITDH 2003
Score = 35.1 bits (77), Expect = 0.70
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 152 DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D G T LH AA + + +AA LL GAD + +++SG+T L
Sbjct: 1836 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPL 1876
Score = 32.7 bits (71), Expect = 3.7
Identities = 20/78 (25%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+N++ L+ +GA+ + D++ TPL A G A+ LL+ A+ ++ LP
Sbjct: 1950 NNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPR 2009
Query: 67 DIAESDAMADLLQKVIDE 84
D+A+ D++ +++D+
Sbjct: 2010 DVAQERLHQDIV-RLLDQ 2026
>AL137618-1|CAB70844.1| 479|Homo sapiens hypothetical protein
protein.
Length = 479
Score = 64.9 bits (151), Expect = 8e-10
Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 3/95 (3%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLV-KKKSSNGTTESST 439
RRS+ PVRDEESE+QRKA ++ +R++RRSTQGVTL ++K AE+ K S +S
Sbjct: 227 RRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLD 286
Query: 440 PTNVKKDETPTPATTDNGSFELEDAGRASPRSGAA 474
P+ ++ P +D+ + E P AA
Sbjct: 287 PS--RRPRVPGVENSDSPAQRAEAPDGQGPGPQAA 319
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 64.9 bits (151), Expect = 8e-10
Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 12/191 (6%)
Query: 6 DDNLDMVEFLVTHGADVN-RGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGEL 64
D + ++ L+ GA + R D G T LH A A+ LL++GAD A ++ G
Sbjct: 1815 DTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRT 1874
Query: 65 PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-----RDL- 118
P+ A + + Q +I + D + +R A+ T + A A+ G VE D+
Sbjct: 1875 PLHTAVTADAQGVFQILIRNRSTDLD-ARMADGSTALILAARLAVEGMVEELIASHADVN 1933
Query: 119 ---KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
+ G + LH AAA ++ LL++ A+ D D + TPL AA G EAA LLL
Sbjct: 1934 AVDELGKSALHWAAAVNNVEATLALLKN-GANKDMQDSKEETPLFLAAREGSYEAAKLLL 1992
Query: 176 KFGADPHLKNY 186
A+ + ++
Sbjct: 1993 DHFANREITDH 2003
Score = 35.1 bits (77), Expect = 0.70
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 152 DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D G T LH AA + + +AA LL GAD + +++SG+T L
Sbjct: 1836 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPL 1876
Score = 32.7 bits (71), Expect = 3.7
Identities = 20/78 (25%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+N++ L+ +GA+ + D++ TPL A G A+ LL+ A+ ++ LP
Sbjct: 1950 NNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPR 2009
Query: 67 DIAESDAMADLLQKVIDE 84
D+A+ D++ +++D+
Sbjct: 2010 DVAQERLHQDIV-RLLDQ 2026
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 64.9 bits (151), Expect = 8e-10
Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 12/191 (6%)
Query: 6 DDNLDMVEFLVTHGADVN-RGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGEL 64
D + ++ L+ GA + R D G T LH A A+ LL++GAD A ++ G
Sbjct: 1775 DTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRT 1834
Query: 65 PVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-----RDL- 118
P+ A + + Q +I + D + +R A+ T + A A+ G VE D+
Sbjct: 1835 PLHTAVTADAQGVFQILIRNRSTDLD-ARMADGSTALILAARLAVEGMVEELIASHADVN 1893
Query: 119 ---KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
+ G + LH AAA ++ LL++ A+ D D + TPL AA G EAA LLL
Sbjct: 1894 AVDELGKSALHWAAAVNNVEATLALLKN-GANKDMQDSKEETPLFLAAREGSYEAAKLLL 1952
Query: 176 KFGADPHLKNY 186
A+ + ++
Sbjct: 1953 DHFANREITDH 1963
Score = 35.1 bits (77), Expect = 0.70
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 152 DYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D G T LH AA + + +AA LL GAD + +++SG+T L
Sbjct: 1796 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPL 1836
Score = 32.7 bits (71), Expect = 3.7
Identities = 20/78 (25%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
+N++ L+ +GA+ + D++ TPL A G A+ LL+ A+ ++ LP
Sbjct: 1910 NNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPR 1969
Query: 67 DIAESDAMADLLQKVIDE 84
D+A+ D++ +++D+
Sbjct: 1970 DVAQERLHQDIV-RLLDQ 1986
>BC008030-1|AAH08030.1| 362|Homo sapiens PPP1R12C protein protein.
Length = 362
Score = 64.5 bits (150), Expect = 1e-09
Identities = 40/107 (37%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 381 RRSFVPPVRDEESETQRKAHAKRVRETRRSTQGVTLDEIKSAEQLV-KKKSSNGTTESST 439
RRS+ PVRDEESE+QRKA ++ +R++RRSTQGVTL ++K AE+ K S +S
Sbjct: 111 RRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLD 170
Query: 440 PTNVKKDETPTPATTDN-GSFELEDAGRASPRSGAAEATVTLPLRRP 485
P+ ++ P +D+ E D P++ V R P
Sbjct: 171 PS--RRPRVPGVENSDSPAQREAPDGQGPGPQAAREHRKVGKEWRGP 215
>BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS
box-containing 2 protein.
Length = 587
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/181 (28%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N + V+ LV H AD N N GWT LH + S + + + L+ GA V + N G
Sbjct: 164 ACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG 223
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWAL-HGYVE 114
P+ +A + L + + + G D + L + E+ L G
Sbjct: 224 ITPLFVAAQSGQLEAL-RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ K G PLH+A+ KG + + LL + + G +PLH AA E L
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR--IRRSGVSPLHLAAERNHDEVLEAL 340
Query: 175 L 175
L
Sbjct: 341 L 341
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/188 (22%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLES-GADVAAVN 59
+ A D + + ++ ++ G ++ + EGW PLH A G + + L + +
Sbjct: 62 IKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRT 121
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-------LHGY 112
E V +A D L ++ +++ E + R+ A H
Sbjct: 122 LQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNA 181
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
G T LH + ++ ++V + L+ A + + G TPL AA GQ EA
Sbjct: 182 DTNHRCNRGWTALHESVSRNDLEVMQILVSG-GAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 173 LLLKFGAD 180
L K+GAD
Sbjct: 241 FLAKYGAD 248
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Query: 108 ALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
A G ++ R L+ T +++A +G++D +LL+ A+PD + TPL+ A
Sbjct: 112 AYPGTIDQRTLQEE-TAVYLATCRGHLDCLLSLLQ-AGAEPDISNKSRETPLYKACERKN 169
Query: 168 KEAAALLLKFGADPHLKNYSGQTCL 192
EA +L++ AD + + G T L
Sbjct: 170 AEAVKILVQHNADTNHRCNRGWTAL 194
>BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/83 (37%), Positives = 47/83 (56%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+AC N+D+V+FL+ GA+VN DN WTPLH G I L+ESGA + A +
Sbjct: 530 MTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASI 589
Query: 61 DGELPVDIAESDAMADLLQKVID 83
+ P++ A D ++ ++D
Sbjct: 590 NNSTPLNRAIESCRLDTVKYLLD 612
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/57 (47%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPL A A G IDV K LLE A+ + D WTPLH A GQ++ LL++ GA
Sbjct: 527 TPLMTACASGNIDVVKFLLEK-GANVNATDNFLWTPLHFACHAGQQDIVELLVESGA 582
Score = 45.2 bits (102), Expect = 7e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +++V ++ G +VN DN+ H A GF I + L DV ++
Sbjct: 190 MEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISI 249
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE 106
+G P+ A AD K I ++G D K +N + T + A+E
Sbjct: 250 NGNTPLHYAAMGGFADCC-KYIAQRGCDL-KWKNLDHKTPRAVAKE 293
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLH--ATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+E L AD+ DNEG L + A LE GADV Y+G+ P+ +
Sbjct: 97 MEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGK-PIFLR 155
Query: 70 ESDAMADLLQKVID--EKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRD-LKTGGT-- 123
+ D+ + EKG + ++ T + +A G VE VR L+ GG
Sbjct: 156 ACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASR---EGVVEIVRGILERGGEVN 212
Query: 124 --------PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
H AA G+ D+ K LL N D + G TPLH AA+ G + +
Sbjct: 213 AFDNDRHHAAHFAAKGGFFDILK-LLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIA 271
Query: 176 KFGADPHLKNYSGQT 190
+ G D KN +T
Sbjct: 272 QRGCDLKWKNLDHKT 286
Score = 39.5 bits (88), Expect = 0.033
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 5/106 (4%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH A G D+ + L+E A D TPL+ A + + LL GA
Sbjct: 560 TPLHFACHAGQQDIVELLVES-GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQ 618
Query: 183 LKNYSGQTCLDL----VDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
L+N G + +D+ D I ++E P+ N K K P
Sbjct: 619 LENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTP 664
Score = 39.5 bits (88), Expect = 0.033
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D+VE LV GA ++ TPL+ + +YLL+ GA N G
Sbjct: 565 ACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKG 624
Query: 63 ELPVDIAESDA---MADLLQKVID 83
+D+A++ A + DL+++ +D
Sbjct: 625 HSAMDVAKAYADYRIIDLIKEKLD 648
Score = 38.7 bits (86), Expect = 0.057
Identities = 48/206 (23%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + +++DMV FL+ GA + D G TP A G L ++ AD+ V+ +G
Sbjct: 55 ASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEG 114
Query: 63 E-------LPVD------IAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDARE 106
+ LP + + AD+ + K + CE + + + D ++ +
Sbjct: 115 KGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVK-DVCLTFLEK 173
Query: 107 WALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
A + + TG T L A+ +G +++ + +LE + + D + H AA G
Sbjct: 174 GANPNAI---NSSTGRTALMEASREGVVEIVRGILER-GGEVNAFDNDRHHAAHFAAKGG 229
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ LL + D L + +G T L
Sbjct: 230 FFDILKLLFAYNGDVGLISINGNTPL 255
Score = 36.3 bits (80), Expect = 0.30
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G + LH+A+ ID+ LL D A PD D G TP AA G + + +L K AD
Sbjct: 48 GLSALHLASVSNDIDMVSFLL-DLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKAD 106
Query: 181 PHLKNYSGQTCL 192
+ + G+ L
Sbjct: 107 MTIVDNEGKGVL 118
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/65 (29%), Positives = 33/65 (50%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G V+ DN TPL + G I + ++LLE GA+V A + P+ A D++
Sbjct: 515 GIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIV 574
Query: 79 QKVID 83
+ +++
Sbjct: 575 ELLVE 579
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 63.7 bits (148), Expect = 2e-09
Identities = 55/175 (31%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G + +A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDL-KTG 121
++ + +V+ G + NA L AR L + V + + G
Sbjct: 62 CQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
T LHVAAA + VAK LLE AD V+ G TPL A E A LL K
Sbjct: 121 DTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLLTK 174
Score = 44.0 bits (99), Expect = 0.002
Identities = 21/63 (33%), Positives = 35/63 (55%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
++L ++ L+T V+ + G T LH A+ +A+ LLE+GAD VN G+ P+
Sbjct: 98 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 157
Query: 67 DIA 69
+ A
Sbjct: 158 ETA 160
Score = 41.5 bits (93), Expect = 0.008
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
R K G T LH A+ G+ AK L++ A+ + G T LH A ++ +LL
Sbjct: 16 RQDKDGNTALHEASWHGFSQSAKLLIK-AGANVLAKNKAGNTALHLACQNSHSQSTRVLL 74
Query: 176 KFGADPHLKNYSGQTCL 192
G+ LKN +G TCL
Sbjct: 75 LAGSRADLKNNAGDTCL 91
Score = 38.3 bits (85), Expect = 0.075
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 136 VAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+A + E C D D +G T LH A+ G ++A LL+K GA+ KN +G T L L
Sbjct: 4 IAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 196 DPSISSWLEEAALKAPRRVN 215
+ S L A R +
Sbjct: 62 CQNSHSQSTRVLLLAGSRAD 81
Score = 33.5 bits (73), Expect = 2.1
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + L+ G+ + +N G T LH A +SI R LL + V N G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNA 95
+ + +A + + K++ E G D NA
Sbjct: 121 DTALHVAAA-LNHKKVAKILLEAGADTTIVNNA 152
>AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/83 (37%), Positives = 47/83 (56%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+AC N+D+V+FL+ GA+VN DN WTPLH G I L+ESGA + A +
Sbjct: 530 MTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASI 589
Query: 61 DGELPVDIAESDAMADLLQKVID 83
+ P++ A D ++ ++D
Sbjct: 590 NNSTPLNRAIESCRLDTVKYLLD 612
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/57 (47%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPL A A G IDV K LLE A+ + D WTPLH A GQ++ LL++ GA
Sbjct: 527 TPLMTACASGNIDVVKFLLEK-GANVNATDNFLWTPLHFACHAGQQDIVELLVESGA 582
Score = 45.2 bits (102), Expect = 7e-04
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M A + +++V ++ G +VN DN+ H A GF I + L DV ++
Sbjct: 190 MEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISI 249
Query: 61 DGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDARE 106
+G P+ A AD K I ++G D K +N + T + A+E
Sbjct: 250 NGNTPLHYAAMGGFADCC-KYIAQRGCDL-KWKNLDHKTPRAVAKE 293
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLH--ATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+E L AD+ DNEG L + A LE GADV Y+G+ P+ +
Sbjct: 97 MEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGK-PIFLR 155
Query: 70 ESDAMADLLQKVID--EKGVDCEKSRNAEVDTLMSDAREWALHGYVE-VRD-LKTGGT-- 123
+ D+ + EKG + ++ T + +A G VE VR L+ GG
Sbjct: 156 ACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASR---EGVVEIVRGILERGGEVN 212
Query: 124 --------PLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
H AA G+ D+ K LL N D + G TPLH AA+ G + +
Sbjct: 213 AFDNDRHHAAHFAAKGGFFDILK-LLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIA 271
Query: 176 KFGADPHLKNYSGQT 190
+ G D KN +T
Sbjct: 272 QRGCDLKWKNLDHKT 286
Score = 39.5 bits (88), Expect = 0.033
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 5/106 (4%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH A G D+ + L+E A D TPL+ A + + LL GA
Sbjct: 560 TPLHFACHAGQQDIVELLVES-GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQ 618
Query: 183 LKNYSGQTCLDL----VDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
L+N G + +D+ D I ++E P+ N K K P
Sbjct: 619 LENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTP 664
Score = 39.5 bits (88), Expect = 0.033
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D+VE LV GA ++ TPL+ + +YLL+ GA N G
Sbjct: 565 ACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKG 624
Query: 63 ELPVDIAESDA---MADLLQKVID 83
+D+A++ A + DL+++ +D
Sbjct: 625 HSAMDVAKAYADYRIIDLIKEKLD 648
Score = 38.7 bits (86), Expect = 0.057
Identities = 48/206 (23%), Positives = 87/206 (42%), Gaps = 21/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + +++DMV FL+ GA + D G TP A G L ++ AD+ V+ +G
Sbjct: 55 ASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEG 114
Query: 63 E-------LPVD------IAESDAMADLLQKVIDEKGV---DCEKSRNAEVDTLMSDARE 106
+ LP + + AD+ + K + CE + + + D ++ +
Sbjct: 115 KGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVK-DVCLTFLEK 173
Query: 107 WALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWG 166
A + + TG T L A+ +G +++ + +LE + + D + H AA G
Sbjct: 174 GANPNAI---NSSTGRTALMEASREGVVEIVRGILER-GGEVNAFDNDRHHAAHFAAKGG 229
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ LL + D L + +G T L
Sbjct: 230 FFDILKLLFAYNGDVGLISINGNTPL 255
Score = 36.3 bits (80), Expect = 0.30
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G + LH+A+ ID+ LL D A PD D G TP AA G + + +L K AD
Sbjct: 48 GLSALHLASVSNDIDMVSFLL-DLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKAD 106
Query: 181 PHLKNYSGQTCL 192
+ + G+ L
Sbjct: 107 MTIVDNEGKGVL 118
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/65 (29%), Positives = 33/65 (50%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G V+ DN TPL + G I + ++LLE GA+V A + P+ A D++
Sbjct: 515 GIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIV 574
Query: 79 QKVID 83
+ +++
Sbjct: 575 ELLVE 579
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 63.7 bits (148), Expect = 2e-09
Identities = 55/175 (31%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G + +A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDL-KTG 121
++ + +V+ G + NA L AR L + V + + G
Sbjct: 62 CQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
T LHVAAA + VAK LLE AD V+ G TPL A E A LL K
Sbjct: 121 DTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLLTK 174
Score = 44.0 bits (99), Expect = 0.002
Identities = 21/63 (33%), Positives = 35/63 (55%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
++L ++ L+T V+ + G T LH A+ +A+ LLE+GAD VN G+ P+
Sbjct: 98 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 157
Query: 67 DIA 69
+ A
Sbjct: 158 ETA 160
Score = 41.5 bits (93), Expect = 0.008
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
R K G T LH A+ G+ AK L++ A+ + G T LH A ++ +LL
Sbjct: 16 RQDKDGNTALHEASWHGFSQSAKLLIK-AGANVLAKNKAGNTALHLACQNSHSQSTRVLL 74
Query: 176 KFGADPHLKNYSGQTCL 192
G+ LKN +G TCL
Sbjct: 75 LAGSRADLKNNAGDTCL 91
Score = 38.3 bits (85), Expect = 0.075
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 136 VAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+A + E C D D +G T LH A+ G ++A LL+K GA+ KN +G T L L
Sbjct: 4 IAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 196 DPSISSWLEEAALKAPRRVN 215
+ S L A R +
Sbjct: 62 CQNSHSQSTRVLLLAGSRAD 81
Score = 33.5 bits (73), Expect = 2.1
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + L+ G+ + +N G T LH A +SI R LL + V N G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNA 95
+ + +A + + K++ E G D NA
Sbjct: 121 DTALHVAAA-LNHKKVAKILLEAGADTTIVNNA 152
>AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21669 fis, clone COL08988. ).
Length = 416
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/83 (37%), Positives = 47/83 (56%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
M+AC N+D+V+FL+ GA+VN DN WTPLH G I L+ESGA + A +
Sbjct: 170 MTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASI 229
Query: 61 DGELPVDIAESDAMADLLQKVID 83
+ P++ A D ++ ++D
Sbjct: 230 NNSTPLNRAIESCRLDTVKYLLD 252
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/57 (47%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
TPL A A G IDV K LLE A+ + D WTPLH A GQ++ LL++ GA
Sbjct: 167 TPLMTACASGNIDVVKFLLEK-GANVNATDNFLWTPLHFACHAGQQDIVELLVESGA 222
Score = 39.5 bits (88), Expect = 0.033
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 5/106 (4%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH A G D+ + L+E A D TPL+ A + + LL GA
Sbjct: 200 TPLHFACHAGQQDIVELLVES-GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQ 258
Query: 183 LKNYSGQTCLDL----VDPSISSWLEEAALKAPRRVNNNKRKLSPP 224
L+N G + +D+ D I ++E P+ N K K P
Sbjct: 259 LENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTP 304
Score = 39.5 bits (88), Expect = 0.033
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC D+VE LV GA ++ TPL+ + +YLL+ GA N G
Sbjct: 205 ACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKG 264
Query: 63 ELPVDIAESDA---MADLLQKVID 83
+D+A++ A + DL+++ +D
Sbjct: 265 HSAMDVAKAYADYRIIDLIKEKLD 288
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/65 (29%), Positives = 33/65 (50%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
G V+ DN TPL + G I + ++LLE GA+V A + P+ A D++
Sbjct: 155 GIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIV 214
Query: 79 QKVID 83
+ +++
Sbjct: 215 ELLVE 219
>AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/181 (28%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N + V+ LV H AD N N GWT LH + S + + + L+ GA V + N G
Sbjct: 164 ACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG 223
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWAL-HGYVE 114
P+ +A + L + + + G D + L + E+ L G
Sbjct: 224 ITPLFVAAQSGQLEAL-RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ K G PLH+A+ KG + + LL + + G +PLH AA E L
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR--IRRSGVSPLHLAAERNHDEVLEAL 340
Query: 175 L 175
L
Sbjct: 341 L 341
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/188 (22%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLES-GADVAAVN 59
+ A D + + ++ ++ G ++ + EGW PLH A G + + L + +
Sbjct: 62 IKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRT 121
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-------LHGY 112
E V +A D L ++ +++ E + R+ A H
Sbjct: 122 LQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNA 181
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
G T LH + ++ ++V + L+ A + + G TPL AA GQ EA
Sbjct: 182 DTNHRCNRGWTALHESVSRNDLEVMQILVSG-GAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 173 LLLKFGAD 180
L K+GAD
Sbjct: 241 FLAKYGAD 248
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Query: 108 ALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
A G ++ R L+ T +++A +G++D +LL+ A+PD + TPL+ A
Sbjct: 112 AYPGTIDQRTLQEE-TAVYLATCRGHLDCLLSLLQ-AGAEPDISNKSRETPLYKACERKN 169
Query: 168 KEAAALLLKFGADPHLKNYSGQTCL 192
EA +L++ AD + + G T L
Sbjct: 170 AEAVKILVQHNADTNHRCNRGWTAL 194
>AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteining
protein with a SOCS box-2 protein.
Length = 587
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/181 (28%), Positives = 76/181 (41%), Gaps = 11/181 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC N + V+ LV H AD N N GWT LH + S + + + L+ GA V + N G
Sbjct: 164 ACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG 223
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWAL-HGYVE 114
P+ +A + L + + + G D + L + E+ L G
Sbjct: 224 ITPLFVAAQSGQLEAL-RFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADA 282
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALL 174
+ K G PLH+A+ KG + + LL + + G +PLH AA E L
Sbjct: 283 NKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR--IRRSGVSPLHLAAERNHDEVLEAL 340
Query: 175 L 175
L
Sbjct: 341 L 341
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/188 (22%), Positives = 75/188 (39%), Gaps = 9/188 (4%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLES-GADVAAVN 59
+ A D + + ++ ++ G ++ + EGW PLH A G + + L + +
Sbjct: 62 IKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRT 121
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-------LHGY 112
E V +A D L ++ +++ E + R+ A H
Sbjct: 122 LQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNA 181
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
G T LH + ++ ++V + L+ A + + G TPL AA GQ EA
Sbjct: 182 DTNHRCNRGWTALHESVSRNDLEVMQILVSG-GAKVESKNAYGITPLFVAAQSGQLEALR 240
Query: 173 LLLKFGAD 180
L K+GAD
Sbjct: 241 FLAKYGAD 248
Score = 37.1 bits (82), Expect = 0.17
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Query: 108 ALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
A G ++ R L+ T +++A +G++D +LL+ A+PD + TPL+ A
Sbjct: 112 AYPGTIDQRTLQEE-TAVYLATCRGHLDCLLSLLQ-AGAEPDISNKSRETPLYKACERKN 169
Query: 168 KEAAALLLKFGADPHLKNYSGQTCL 192
EA +L++ AD + + G T L
Sbjct: 170 AEAVKILVQHNADTNHRCNRGWTAL 194
>U58334-1|AAC50557.1| 1005|Homo sapiens Bbp/53BP2 protein.
Length = 1005
Score = 63.3 bits (147), Expect = 2e-09
Identities = 25/51 (49%), Positives = 37/51 (72%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++V+FLV G +VN D++GWTPLH ASC + + ++L+ESGA V A+ Y
Sbjct: 850 EIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
Score = 43.6 bits (98), Expect = 0.002
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH A G+ ++ K L++ + + D +GWTPLH AA + L++ GA
Sbjct: 836 GITALHNAVCAGHTEIVKFLVQ-FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
Query: 181 PHLKNYSG-QTCLD 193
YS QT D
Sbjct: 895 VFAMTYSDMQTAAD 908
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ + ++ D+V+ ++ D + ++EG T LH G I ++L++ G +V A +
Sbjct: 808 LDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 867
Query: 61 DGELPVDIAES 71
DG P+ A S
Sbjct: 868 DGWTPLHCAAS 878
Score = 31.9 bits (69), Expect = 6.5
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
++ +G D+ + ++ + + DP + EG T LH A G E L++FG + + +
Sbjct: 810 SSLEGEFDLVQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSD 868
Query: 188 GQTCL 192
G T L
Sbjct: 869 GWTPL 873
>U09582-1|AAA21597.1| 529|Homo sapiens p53-binding protein protein.
Length = 529
Score = 63.3 bits (147), Expect = 2e-09
Identities = 25/51 (49%), Positives = 37/51 (72%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++V+FLV G +VN D++GWTPLH ASC + + ++L+ESGA V A+ Y
Sbjct: 374 EIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 424
Score = 43.6 bits (98), Expect = 0.002
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH A G+ ++ K L++ + + D +GWTPLH AA + L++ GA
Sbjct: 360 GITALHNAVCAGHTEIVKFLVQ-FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 418
Query: 181 PHLKNYSG-QTCLD 193
YS QT D
Sbjct: 419 VFAMTYSDMQTAAD 432
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ + ++ D+V+ ++ D + ++EG T LH G I ++L++ G +V A +
Sbjct: 332 LDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 391
Query: 61 DGELPVDIAES 71
DG P+ A S
Sbjct: 392 DGWTPLHCAAS 402
Score = 31.9 bits (69), Expect = 6.5
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
++ +G D+ + ++ + + DP + EG T LH A G E L++FG + + +
Sbjct: 334 SSLEGEFDLVQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSD 392
Query: 188 GQTCL 192
G T L
Sbjct: 393 GWTPL 397
>BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein
protein.
Length = 302
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/214 (29%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A L ++ L+ G +VN + LH G ++ A+ LLE+GA V V G
Sbjct: 51 AAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHG 110
Query: 63 ELPVDIAESDAMADLLQKVID-----EKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-R 116
P+ A A + +++ + V + V + E L V +
Sbjct: 111 ATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDH 170
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALL 174
++ GTPL+VA +D K LLE A VD+ W TPLHAAA E LL
Sbjct: 171 EVPQLGTPLYVACTYQRVDCVKKLLE-LGAS---VDHGQWLDTPLHAAARQSNVEVIHLL 226
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+GA+ +N G++ LDL P S +E+A L
Sbjct: 227 TDYGANLKRRNAQGKSALDLAAPKSS--VEQALL 258
Score = 34.7 bits (76), Expect = 0.93
Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 1/114 (0%)
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
D + +PLH AAA+G + KTL+ + + V + LH A L G A LL+
Sbjct: 40 DCRADRSPLHEAAAQGRLLALKTLIAQ-GVNVNLVTINRVSSLHEACLGGHVACAKALLE 98
Query: 177 FGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
GA + G T L S S+ L+ + SP VKR
Sbjct: 99 NGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKR 152
>BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing 11 protein.
Length = 323
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/214 (29%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A L ++ L+ G +VN + LH G ++ A+ LLE+GA V V G
Sbjct: 72 AAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHG 131
Query: 63 ELPVDIAESDAMADLLQKVID-----EKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-R 116
P+ A A + +++ + V + V + E L V +
Sbjct: 132 ATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDH 191
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALL 174
++ GTPL+VA +D K LLE A VD+ W TPLHAAA E LL
Sbjct: 192 EVPQLGTPLYVACTYQRVDCVKKLLE-LGAS---VDHGQWLDTPLHAAARQSNVEVIHLL 247
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+GA+ +N G++ LDL P S +E+A L
Sbjct: 248 TDYGANLKRRNAQGKSALDLAAPKSS--VEQALL 279
Score = 34.3 bits (75), Expect = 1.2
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
Y + D +PLH AAA+G + KTL+ + + V + LH A L G A
Sbjct: 56 YGGISDCWADRSPLHEAAAQGRLLALKTLIAQ-GVNVNLVTINRVSSLHEACLGGHVACA 114
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
LL+ GA + G T L S S+ L+ + SP VKR
Sbjct: 115 KALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKR 173
>BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing 11 protein.
Length = 323
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/214 (29%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A L ++ L+ G +VN + LH G ++ A+ LLE+GA V V G
Sbjct: 72 AAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHG 131
Query: 63 ELPVDIAESDAMADLLQKVID-----EKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-R 116
P+ A A + +++ + V + V + E L V +
Sbjct: 132 ATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDH 191
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALL 174
++ GTPL+VA +D K LLE A VD+ W TPLHAAA E LL
Sbjct: 192 EVPQLGTPLYVACTYQRVDCVKKLLE-LGAS---VDHGQWLDTPLHAAARQSNVEVIHLL 247
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+GA+ +N G++ LDL P S +E+A L
Sbjct: 248 TDYGANLKRRNAQGKSALDLAAPKSS--VEQALL 279
Score = 34.3 bits (75), Expect = 1.2
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
Y + D +PLH AAA+G + KTL+ + + V + LH A L G A
Sbjct: 56 YGGISDCWADRSPLHEAAAQGRLLALKTLIAQ-GVNVNLVTINRVSSLHEACLGGHVACA 114
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
LL+ GA + G T L S S+ L+ + SP VKR
Sbjct: 115 KALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKR 173
>BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing protein 11 protein.
Length = 323
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/214 (29%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A L ++ L+ G +VN + LH G ++ A+ LLE+GA V V G
Sbjct: 72 AAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHG 131
Query: 63 ELPVDIAESDAMADLLQKVID-----EKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-R 116
P+ A A + +++ + V + V + E L V +
Sbjct: 132 ATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDH 191
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALL 174
++ GTPL+VA +D K LLE A VD+ W TPLHAAA E LL
Sbjct: 192 EVPQLGTPLYVACTYQRVDCVKKLLE-LGAS---VDHGQWLDTPLHAAARQSNVEVIHLL 247
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+GA+ +N G++ LDL P S +E+A L
Sbjct: 248 TDYGANLKRRNAQGKSALDLAAPKSS--VEQALL 279
Score = 34.3 bits (75), Expect = 1.2
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
Y + D +PLH AAA+G + KTL+ + + V + LH A L G A
Sbjct: 56 YGGISDCWADRSPLHEAAAQGRLLALKTLIAQ-GVNVNLVTINRVSSLHEACLGGHVACA 114
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
LL+ GA + G T L S S+ L+ + SP VKR
Sbjct: 115 KALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKR 173
>BC058918-1|AAH58918.1| 1127|Homo sapiens tumor protein p53 binding
protein, 2 protein.
Length = 1127
Score = 63.3 bits (147), Expect = 2e-09
Identities = 25/51 (49%), Positives = 37/51 (72%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++V+FLV G +VN D++GWTPLH ASC + + ++L+ESGA V A+ Y
Sbjct: 972 EIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1022
Score = 43.6 bits (98), Expect = 0.002
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH A G+ ++ K L++ + + D +GWTPLH AA + L++ GA
Sbjct: 958 GITALHNAVCAGHTEIVKFLVQ-FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1016
Query: 181 PHLKNYSG-QTCLD 193
YS QT D
Sbjct: 1017 VFAMTYSDMQTAAD 1030
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ + ++ D+V+ ++ D + ++EG T LH G I ++L++ G +V A +
Sbjct: 930 LDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 989
Query: 61 DGELPVDIAES 71
DG P+ A S
Sbjct: 990 DGWTPLHCAAS 1000
Score = 31.9 bits (69), Expect = 6.5
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
++ +G D+ + ++ + + DP + EG T LH A G E L++FG + + +
Sbjct: 932 SSLEGEFDLVQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSD 990
Query: 188 GQTCL 192
G T L
Sbjct: 991 GWTPL 995
>BC040247-1|AAH40247.1| 1048|Homo sapiens TP53BP2 protein protein.
Length = 1048
Score = 63.3 bits (147), Expect = 2e-09
Identities = 25/51 (49%), Positives = 37/51 (72%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++V+FLV G +VN D++GWTPLH ASC + + ++L+ESGA V A+ Y
Sbjct: 893 EIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 943
Score = 43.6 bits (98), Expect = 0.002
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH A G+ ++ K L++ + + D +GWTPLH AA + L++ GA
Sbjct: 879 GITALHNAVCAGHTEIVKFLVQ-FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 937
Query: 181 PHLKNYSG-QTCLD 193
YS QT D
Sbjct: 938 VFAMTYSDMQTAAD 951
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ + ++ D+V+ ++ D + ++EG T LH G I ++L++ G +V A +
Sbjct: 851 LDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 910
Query: 61 DGELPVDIAES 71
DG P+ A S
Sbjct: 911 DGWTPLHCAAS 921
Score = 31.9 bits (69), Expect = 6.5
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
++ +G D+ + ++ + + DP + EG T LH A G E L++FG + + +
Sbjct: 853 SSLEGEFDLVQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSD 911
Query: 188 GQTCL 192
G T L
Sbjct: 912 GWTPL 916
>AL390918-3|CAI15823.1| 878|Homo sapiens protein ( Human DNA
sequence from clone RP11-569E4 on chromosome 13. ).
Length = 878
Score = 63.3 bits (147), Expect = 2e-09
Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PHL
Sbjct: 14 LHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLV 72
Query: 185 NYSGQTCLDLVDPSISSWLEEAALKA 210
N + + D+ + S ++EE LKA
Sbjct: 73 NCNEEKASDI---AASEFIEEMLLKA 95
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 17 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 76
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 77 EKASDIAASEFIEEMLLK 94
>AL353143-3|CAH73223.1| 878|Homo sapiens protein ( Human DNA
sequence from clone RP11-383F12 on chromosome 13. ).
Length = 878
Score = 63.3 bits (147), Expect = 2e-09
Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PHL
Sbjct: 14 LHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLV 72
Query: 185 NYSGQTCLDLVDPSISSWLEEAALKA 210
N + + D+ + S ++EE LKA
Sbjct: 73 NCNEEKASDI---AASEFIEEMLLKA 95
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 17 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 76
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 77 EKASDIAASEFIEEMLLK 94
>AL136132-3|CAH70521.1| 878|Homo sapiens protein ( Human DNA
sequence from clone RP11-141M24 on chromosome
13q33.1-34. ).
Length = 878
Score = 63.3 bits (147), Expect = 2e-09
Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
LH+A A GY +V +LE D + VD + WTPLH AA +GQ LLL A+PHL
Sbjct: 14 LHMACASGYKEVVSLILEH-GGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLV 72
Query: 185 NYSGQTCLDLVDPSISSWLEEAALKA 210
N + + D+ + S ++EE LKA
Sbjct: 73 NCNEEKASDI---AASEFIEEMLLKA 95
Score = 53.6 bits (123), Expect = 2e-06
Identities = 27/78 (34%), Positives = 43/78 (55%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC ++V ++ HG D+N D++ WTPLH A G ++ + LL A+ VN +
Sbjct: 17 ACASGYKEVVSLILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNE 76
Query: 63 ELPVDIAESDAMADLLQK 80
E DIA S+ + ++L K
Sbjct: 77 EKASDIAASEFIEEMLLK 94
>AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein
protein.
Length = 641
Score = 63.3 bits (147), Expect = 2e-09
Identities = 55/175 (31%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIA 69
+++ L+ G ++R D +G T LH + GF A+ L+++GA+V A N G + +A
Sbjct: 3 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLA 62
Query: 70 ESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAR-------EWALHGYVEVRDL-KTG 121
++ + +V+ G + NA L AR L + V + + G
Sbjct: 63 CQNSHSQ-STRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 121
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK 176
T LHVAAA + VAK LLE AD V+ G TPL A E A LL K
Sbjct: 122 DTALHVAAALNHKKVAKILLE-AGADTTIVNNAGQTPLETARYHNNPEVALLLTK 175
Score = 44.0 bits (99), Expect = 0.002
Identities = 21/63 (33%), Positives = 35/63 (55%)
Query: 7 DNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPV 66
++L ++ L+T V+ + G T LH A+ +A+ LLE+GAD VN G+ P+
Sbjct: 99 NHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 158
Query: 67 DIA 69
+ A
Sbjct: 159 ETA 161
Score = 41.1 bits (92), Expect = 0.011
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Query: 116 RDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLL 175
R K G T LH A+ G+ AK L++ A+ + G T LH A ++ +LL
Sbjct: 17 RQDKDGNTALHEASWHGFSQSAKLLVK-AGANVLAKNKAGNTALHLACQNSHSQSTRVLL 75
Query: 176 KFGADPHLKNYSGQTCL 192
G+ LKN +G TCL
Sbjct: 76 LAGSRADLKNNAGDTCL 92
Score = 37.9 bits (84), Expect = 0.099
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 136 VAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
+A + E C D D +G T LH A+ G ++A LL+K GA+ KN +G T L L
Sbjct: 5 IAALIHEGCALDRQ--DKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLA 62
Query: 196 DPSISSWLEEAALKAPRRVN 215
+ S L A R +
Sbjct: 63 CQNSHSQSTRVLLLAGSRAD 82
Score = 33.5 bits (73), Expect = 2.1
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + L+ G+ + +N G T LH A +SI R LL + V N G
Sbjct: 62 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 121
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNA 95
+ + +A + + K++ E G D NA
Sbjct: 122 DTALHVAAA-LNHKKVAKILLEAGADTTIVNNA 153
>AJ318888-1|CAC83012.1| 1128|Homo sapiens ASPP2 protein protein.
Length = 1128
Score = 63.3 bits (147), Expect = 2e-09
Identities = 25/51 (49%), Positives = 37/51 (72%)
Query: 10 DMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
++V+FLV G +VN D++GWTPLH ASC + + ++L+ESGA V A+ Y
Sbjct: 973 EIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1023
Score = 43.6 bits (98), Expect = 0.002
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G T LH A G+ ++ K L++ + + D +GWTPLH AA + L++ GA
Sbjct: 959 GITALHNAVCAGHTEIVKFLVQ-FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 1017
Query: 181 PHLKNYSG-QTCLD 193
YS QT D
Sbjct: 1018 VFAMTYSDMQTAAD 1031
Score = 39.9 bits (89), Expect = 0.025
Identities = 19/71 (26%), Positives = 37/71 (52%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNY 60
+ + ++ D+V+ ++ D + ++EG T LH G I ++L++ G +V A +
Sbjct: 931 LDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADS 990
Query: 61 DGELPVDIAES 71
DG P+ A S
Sbjct: 991 DGWTPLHCAAS 1001
Score = 31.9 bits (69), Expect = 6.5
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 128 AAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYS 187
++ +G D+ + ++ + + DP + EG T LH A G E L++FG + + +
Sbjct: 933 SSLEGEFDLVQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSD 991
Query: 188 GQTCL 192
G T L
Sbjct: 992 GWTPL 996
>AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat
domain-containing SOCS box protein ASB11 protein.
Length = 323
Score = 63.3 bits (147), Expect = 2e-09
Identities = 63/214 (29%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A L ++ L+ G +VN + LH G ++ A+ LLE+GA V V G
Sbjct: 72 AAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHG 131
Query: 63 ELPVDIAESDAMADLLQKVID-----EKGVDCEKSRNAEVDTLMSDAREWALHGYVEV-R 116
P+ A A + +++ + V + V + E L V +
Sbjct: 132 ATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDH 191
Query: 117 DLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGW--TPLHAAALWGQKEAAALL 174
++ GTPL+VA +D K LLE A VD+ W TPLHAAA E LL
Sbjct: 192 EVPQLGTPLYVACTYQRVDCVKKLLE-LGAS---VDHGQWLDTPLHAAARQSNVEVIHLL 247
Query: 175 LKFGADPHLKNYSGQTCLDLVDPSISSWLEEAAL 208
+GA+ +N G++ LDL P S +E+A L
Sbjct: 248 TDYGANLKRRNAQGKSALDLAAPKSS--VEQALL 279
Score = 34.3 bits (75), Expect = 1.2
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 1/119 (0%)
Query: 112 YVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAA 171
Y + D +PLH AAA+G + KTL+ + + V + LH A L G A
Sbjct: 56 YGGISDCWADRSPLHEAAAQGRLLALKTLIAQ-GVNVNLVTINRVSSLHEACLGGHVACA 114
Query: 172 ALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRHEVKR 230
LL+ GA + G T L S S+ L+ + SP VKR
Sbjct: 115 KALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKR 173
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/185 (28%), Positives = 87/185 (47%), Gaps = 10/185 (5%)
Query: 9 LDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDI 68
LD ++FLV G D N D EG T LH A G +++ + L++ G D+ N +G +
Sbjct: 81 LDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHS 140
Query: 69 AESDAMADLLQKVIDEKG-VDCEKSRNAEVDTLMS-----DAREWALH--GYVEVRDLKT 120
A + D +Q ++ V+ +N + D +H G V D +
Sbjct: 141 AAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQ- 199
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G +PLH+A + + + L+ ++D + VD TPLH AA ++ A +LL G D
Sbjct: 200 GASPLHLAVRHNFPALVRLLINS-DSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 181 PHLKN 185
+L++
Sbjct: 259 LNLRD 263
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 29/187 (15%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD--GELP 65
+L +++ LV GA ++ +G T LH A G + + +++E DVA + D G
Sbjct: 12 HLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTA 71
Query: 66 VDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPL 125
A D L ++ G C+ + V+D K G T L
Sbjct: 72 FHRAAEHGQLDALDFLV---GSGCDHN----------------------VKD-KEGNTAL 105
Query: 126 HVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKN 185
H+AA +G++ V + L+ D D + + EG T LH+AA + LLL+ G+ +
Sbjct: 106 HLAAGRGHMAVLQRLV-DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALT 164
Query: 186 YSGQTCL 192
+CL
Sbjct: 165 QKNLSCL 171
Score = 48.8 bits (111), Expect = 5e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 16/209 (7%)
Query: 26 DNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEK 85
D G T H A G + +L+ SG D + +G + +A +LQ+++D
Sbjct: 65 DKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDI- 123
Query: 86 GVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTP----------LHVAAAKGYID 135
G+D E+ +NAE T + A + V++ L+ G T LH AA G D
Sbjct: 124 GLDLEE-QNAEGLTALHSAAGGSHPDCVQLL-LRAGSTVNALTQKNLSCLHYAALSGSED 181
Query: 136 VAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDLV 195
V++ L+ + VD++G +PLH A LL+ +D + + QT L L
Sbjct: 182 VSRVLIH-AGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Query: 196 DPSISSWLEEAALKAPRRVNNNKRKLSPP 224
+ +W + A + V+ N R P
Sbjct: 241 --AEHAWQDIADMLLIAGVDLNLRDKDHP 267
Score = 42.3 bits (95), Expect = 0.005
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A + + D+ L+ G N D++G +PLH F ++ R L+ S +DV AV+
Sbjct: 174 AALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQ 233
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ P+ +A A D+ ++ GVD
Sbjct: 234 QTPLHLAAEHAWQDIADMLL-IAGVD 258
>EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat
protein transcript variant 2 protein.
Length = 782
Score = 62.5 bits (145), Expect = 4e-09
Identities = 48/193 (24%), Positives = 87/193 (45%), Gaps = 13/193 (6%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
++ D + D W P+H A G + + L++ G + V+Y+G LPV +A +
Sbjct: 409 IMLRSGDPSVTDKREWRPVHYAAFHGRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGH 468
Query: 75 ADLLQKVIDEKGVDCE--KSRNAEVDTLMSDAREWALHGYVE-----------VRDLKTG 121
+ ++ + K+ N + ++ A+ + ++ + D +T
Sbjct: 469 LHCFKFLVSRMSSATQVLKAFNDNGENVLDLAQRFFKQNILQFIQGAEYEGKDLEDQETL 528
Query: 122 GTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
P HVAA KG + + K L+ED + + G TP+H AA G E L+K GAD
Sbjct: 529 AFPGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADS 588
Query: 182 HLKNYSGQTCLDL 194
++ N +G+ D+
Sbjct: 589 NITNKAGERPSDV 601
Score = 48.4 bits (110), Expect = 7e-05
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 34/192 (17%)
Query: 8 NLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVD 67
+L+ + +L+ HGAD+ GWT H A G + + L+ +GA++ A + G P+
Sbjct: 337 SLECLHWLLWHGADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLTAQDDRGCTPLH 396
Query: 68 IAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHV 127
+A + + LQ ++ G D ++D REW P+H
Sbjct: 397 LAATHGHSFTLQ-IMLRSG-----------DPSVTDKREW---------------RPVHY 429
Query: 128 AAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLK--FGADPHLK 184
AA G + + L++ C+ + VDY G P+H AA+ G L+ A LK
Sbjct: 430 AAFHGRLGCLQLLVKWGCSIED--VDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLK 487
Query: 185 --NYSGQTCLDL 194
N +G+ LDL
Sbjct: 488 AFNDNGENVLDL 499
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 5/118 (4%)
Query: 3 ACIDDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A +L M++ LV G ++N + G TP+H A G I ++L++ GAD N
Sbjct: 535 AAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNITNKA 594
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
GE P D+A+ A ++ + + + D + E+D +D + + HG D K
Sbjct: 595 GERPSDVAKRFAHLAAVKLLEELQKYDIDDEN--EIDE--NDVKYFIRHGVEGSTDAK 648
Score = 39.5 bits (88), Expect = 0.033
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 123 TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPH 182
TPLH AA G ++ LL AD V GWT H AA+ GQ L+ GA+
Sbjct: 327 TPLHWAAHSGSLECLHWLLWH-GADITHVTTRGWTASHIAAIRGQDACVQALIMNGANLT 385
Query: 183 LKNYSGQTCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSP 223
++ G T L L S+ + L++ +KR+ P
Sbjct: 386 AQDDRGCTPLHLAATHGHSFTLQIMLRSGDPSVTDKREWRP 426
>BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing 7 protein.
Length = 274
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
+N N+GWTPLH A G S R LLE A+V ++ G P+ +A + ++ +
Sbjct: 110 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169
Query: 82 IDEK-GVDCEKS---RNAEVDTLMSDAREWALHGY-VEVRDLKTGGTPLHVAAAKGYIDV 136
+D +D + R A + + S R + G + L+ G TPLH++A + +
Sbjct: 170 LDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLC 229
Query: 137 AKTLLEDCNADPDCVDYEGWTPL 159
A+ +L + AD + +YEG TPL
Sbjct: 230 AR-MLYNYGADTNTRNYEGQTPL 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADP-DCVDYEGWTPLHAAALWGQKEAAA 172
V+DL G T LH AA G +A+ +LE + +D + +GWTPLH AA +G+
Sbjct: 75 VKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVR 134
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL+F A+ + G T L L
Sbjct: 135 LLLEFKAEVDPLSDKGTTPLQL 156
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A I N + GAD N G E G TPLH +A + AR L GAD NY+
Sbjct: 187 AVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYE 246
Query: 62 GELPVDIAES 71
G+ P+ ++ S
Sbjct: 247 GQTPLAVSIS 256
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A A G + + +LE P+ D GWT LH +A G++ + L+ GADP +K
Sbjct: 18 IQAAVAAGDVHTVRKMLEQ-GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVK 76
Query: 185 NYSG 188
+ G
Sbjct: 77 DLIG 80
Score = 36.7 bits (81), Expect = 0.23
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YDGELPVDIAE 70
V ++ G N D GWT LH +A+ G R LE GAD + G + A
Sbjct: 30 VRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAA 89
Query: 71 SDAMADLLQKVID-EKGVDCEKSRNAEVDTLMSDAREWALHGYV--------EVRDLK-T 120
A + + +++ E D +++ + T + A + +V EV L
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPL +A + K LL D NA+ +D + L A + + L+ GAD
Sbjct: 150 GTTPLQLAIIRERSSCVKILL-DHNAN---IDIQNGFLLRYAVIKSNHSYCRMFLQRGAD 205
Query: 181 PHL-KNYSGQTCLDL 194
+L + GQT L L
Sbjct: 206 TNLGRLEDGQTPLHL 220
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 62.1 bits (144), Expect = 5e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 13/233 (5%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
GA + D+EG T H A+ G + R ++ G DV A + G + +A ++ + +
Sbjct: 43 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 102
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGY---------VEVRDLKTGGTPLHVAA 129
+K++ K E ++ L A + L + ++DL G PL +A
Sbjct: 103 RKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLD-GNIPLLLAV 160
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
G+ ++ LL D AD + + G T L A G A L+K GAD +L + G
Sbjct: 161 QNGHSEICHFLL-DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGY 219
Query: 190 TCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH-EVKRIDIEIKGQAEK 241
L S ++ ++ L + + K P +H +V +I E G +K
Sbjct: 220 NALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKK 272
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 62.1 bits (144), Expect = 5e-09
Identities = 52/169 (30%), Positives = 80/169 (47%), Gaps = 9/169 (5%)
Query: 33 LHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKG-VD-CE 90
LH A+CG + LL+ GA+ + G P+ +A + + K+++ V+ C
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 91 KSRNAEVDTLMSDAREWALHGYVE-VRDLKT----GGTPLHVAAAKGYIDVAKTLLEDCN 145
+ L + R LH V+ V D+ G T LHVA G+ + LL D
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL-DSG 187
Query: 146 ADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
AD + + G TPL+ A GQ++ A +LL GA +L + +G T LDL
Sbjct: 188 ADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVTPLDL 235
Score = 42.7 bits (96), Expect = 0.003
Identities = 24/75 (32%), Positives = 36/75 (48%)
Query: 5 IDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGEL 64
++ +++ LV H +DV+ D G T LH G + + LL+SGAD+ N G
Sbjct: 140 VNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGAT 199
Query: 65 PVDIAESDAMADLLQ 79
P+ A S D Q
Sbjct: 200 PLYFACSHGQRDTAQ 214
Score = 37.1 bits (82), Expect = 0.17
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + + V+ L+ GAD+NR + G TPL+ S G A+ LL GA + +G
Sbjct: 171 ACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLP-DKNG 229
Query: 63 ELPVDIAESDAMADLLQKVI 82
P+D+ + + +I
Sbjct: 230 VTPLDLCVQGGYGETCEVLI 249
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 62.1 bits (144), Expect = 5e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 13/233 (5%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
GA + D+EG T H A+ G + R ++ G DV A + G + +A ++ + +
Sbjct: 46 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 105
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGY---------VEVRDLKTGGTPLHVAA 129
+K++ K E ++ L A + L + ++DL G PL +A
Sbjct: 106 RKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLD-GNIPLLLAV 163
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
G+ ++ LL D AD + + G T L A G A L+K GAD +L + G
Sbjct: 164 QNGHSEICHFLL-DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGY 222
Query: 190 TCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH-EVKRIDIEIKGQAEK 241
L S ++ ++ L + + K P +H +V +I E G +K
Sbjct: 223 NALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKK 275
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 623 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 682
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 683 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 737
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 738 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 795
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 796 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 855
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 856 LMSAFRKGHVKVVQYLVKEVN 876
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 556 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 615
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 616 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 670
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 671 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 729
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 730 RAEVVSLLLDRKANVEHRAKTGLTPL 755
Score = 50.0 bits (114), Expect = 2e-05
Identities = 48/175 (27%), Positives = 81/175 (46%), Gaps = 12/175 (6%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
GAD+ G + TPL + G + + +YLL SGA+V A G+ + A + D+
Sbjct: 3 GADIELGCS---TPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVA 59
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAK 138
V+ + G D +K ++ T++ + + A H + + + G TPL AA G++ +
Sbjct: 60 D-VLLQAGADLDKQE--DMKTIL-EGIDPAKH---QEHESEGGRTPLMKAARAGHLCTVQ 112
Query: 139 TLL-EDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
L+ + N + + + T + A G LLL GADP + G T L
Sbjct: 113 FLISKGANVNRATANND-HTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 166
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 575 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 633
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 634 LLLARGANKEHRNVSDYTPLSL 655
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV 58
AC +L +VE L+ HGAD +G T L A G ++ YLL+ +V +V
Sbjct: 136 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSV 191
Score = 34.3 bits (75), Expect = 1.2
Identities = 18/55 (32%), Positives = 31/55 (56%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV 55
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+
Sbjct: 15 MEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 69
Score = 33.9 bits (74), Expect = 1.6
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGD-NEGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A +L V+FL++ GA+VNR N T + + G +++ LL GAD
Sbjct: 100 MKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL 159
Query: 60 YDGELPVDIAESDAMADLLQKVID 83
DG + A +++ ++D
Sbjct: 160 KDGSTMLIEAAKGGHTNVVSYLLD 183
>AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
+N N+GWTPLH A G S R LLE A+V ++ G P+ +A + ++ +
Sbjct: 110 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKIL 169
Query: 82 IDEK-GVDCEKS---RNAEVDTLMSDAREWALHGY-VEVRDLKTGGTPLHVAAAKGYIDV 136
+D +D + R A + + S R + G + L+ G TPLH++A + +
Sbjct: 170 LDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLC 229
Query: 137 AKTLLEDCNADPDCVDYEGWTPL 159
A+ +L + AD + +YEG TPL
Sbjct: 230 AR-MLYNYGADTNTRNYEGQTPL 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADP-DCVDYEGWTPLHAAALWGQKEAAA 172
V+DL G T LH AA G +A+ +LE + +D + +GWTPLH AA +G+
Sbjct: 75 VKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVR 134
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL+F A+ + G T L L
Sbjct: 135 LLLEFKAEVDPLSDKGTTPLQL 156
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A I N + GAD N G E G TPLH +A + AR L GAD NY+
Sbjct: 187 AVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYE 246
Query: 62 GELPVDIAES 71
G+ P+ ++ S
Sbjct: 247 GQTPLAVSIS 256
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A A G + + +LE P+ D GWT LH +A G++ + L+ GADP +K
Sbjct: 18 IQAAVAAGDVHTVRKMLEQ-GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVK 76
Query: 185 NYSG 188
+ G
Sbjct: 77 DLIG 80
Score = 36.7 bits (81), Expect = 0.23
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YDGELPVDIAE 70
V ++ G N D GWT LH +A+ G R LE GAD + G + A
Sbjct: 30 VRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAA 89
Query: 71 SDAMADLLQKVID-EKGVDCEKSRNAEVDTLMSDAREWALHGYV--------EVRDLK-T 120
A + + +++ E D +++ + T + A + +V EV L
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPL +A + K LL D NA+ +D + L A + + L+ GAD
Sbjct: 150 GTTPLQLAIIREKSSCVKILL-DHNAN---IDIQNGFLLRYAVIKSNHSYCRMFLQRGAD 205
Query: 181 PHL-KNYSGQTCLDL 194
+L + GQT L L
Sbjct: 206 TNLGRLEDGQTPLHL 220
>AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
+N N+GWTPLH A G S R LLE A+V ++ G P+ +A + ++ +
Sbjct: 110 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKIL 169
Query: 82 IDEK-GVDCEKS---RNAEVDTLMSDAREWALHGY-VEVRDLKTGGTPLHVAAAKGYIDV 136
+D +D + R A + + S R + G + L+ G TPLH++A + +
Sbjct: 170 LDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLC 229
Query: 137 AKTLLEDCNADPDCVDYEGWTPL 159
A+ +L + AD + +YEG TPL
Sbjct: 230 AR-MLYNYGADTNTRNYEGQTPL 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADP-DCVDYEGWTPLHAAALWGQKEAAA 172
V+DL G T LH AA G +A+ +LE + +D + +GWTPLH AA +G+
Sbjct: 75 VKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVR 134
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL+F A+ + G T L L
Sbjct: 135 LLLEFKAEVDPLSDKGTTPLQL 156
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A I N + GAD N G E G TPLH +A + AR L GAD NY+
Sbjct: 187 AVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYE 246
Query: 62 GELPVDIAES 71
G+ P+ ++ S
Sbjct: 247 GQTPLAVSIS 256
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A A G + + +LE P+ D GWT LH +A G++ + L+ GADP +K
Sbjct: 18 IQAAVAAGDVHTVRKMLEQ-GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVK 76
Query: 185 NYSG 188
+ G
Sbjct: 77 DLIG 80
Score = 36.7 bits (81), Expect = 0.23
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YDGELPVDIAE 70
V ++ G N D GWT LH +A+ G R LE GAD + G + A
Sbjct: 30 VRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAA 89
Query: 71 SDAMADLLQKVID-EKGVDCEKSRNAEVDTLMSDAREWALHGYV--------EVRDLK-T 120
A + + +++ E D +++ + T + A + +V EV L
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPL +A + K LL D NA+ +D + L A + + L+ GAD
Sbjct: 150 GTTPLQLAIIREKSSCVKILL-DHNAN---IDIQNGFLLRYAVIKSNHSYCRMFLQRGAD 205
Query: 181 PHL-KNYSGQTCLDL 194
+L + GQT L L
Sbjct: 206 TNLGRLEDGQTPLHL 220
>AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22551 fis, clone HSI00804. ).
Length = 274
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
+N N+GWTPLH A G S R LLE A+V ++ G P+ +A + ++ +
Sbjct: 110 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKIL 169
Query: 82 IDEK-GVDCEKS---RNAEVDTLMSDAREWALHGY-VEVRDLKTGGTPLHVAAAKGYIDV 136
+D +D + R A + + S R + G + L+ G TPLH++A + +
Sbjct: 170 LDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLC 229
Query: 137 AKTLLEDCNADPDCVDYEGWTPL 159
A+ +L + AD + +YEG TPL
Sbjct: 230 AR-MLYNYGADTNTRNYEGQTPL 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADP-DCVDYEGWTPLHAAALWGQKEAAA 172
V+DL G T LH AA G +A+ +LE + +D + +GWTPLH AA +G+
Sbjct: 75 VKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVR 134
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL+F A+ + G T L L
Sbjct: 135 LLLEFKAEVDPLSDKGTTPLQL 156
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A I N + GAD N G E G TPLH +A + AR L GAD NY+
Sbjct: 187 AVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYE 246
Query: 62 GELPVDIAES 71
G+ P+ ++ S
Sbjct: 247 GQTPLAVSIS 256
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A A G + + +LE P+ D GWT LH +A G++ + L+ GADP +K
Sbjct: 18 IQAAVAAGDVHTVRKMLEQ-GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVK 76
Query: 185 NYSG 188
+ G
Sbjct: 77 DLIG 80
Score = 36.7 bits (81), Expect = 0.23
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YDGELPVDIAE 70
V ++ G N D GWT LH +A+ G R LE GAD + G + A
Sbjct: 30 VRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAA 89
Query: 71 SDAMADLLQKVID-EKGVDCEKSRNAEVDTLMSDAREWALHGYV--------EVRDLK-T 120
A + + +++ E D +++ + T + A + +V EV L
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPL +A + K LL D NA+ +D + L A + + L+ GAD
Sbjct: 150 GTTPLQLAIIREKSSCVKILL-DHNAN---IDIQNGFLLRYAVIKSNHSYCRMFLQRGAD 205
Query: 181 PHL-KNYSGQTCLDL 194
+L + GQT L L
Sbjct: 206 TNLGRLEDGQTPLHL 220
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 340 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 399
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 400 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 454
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 455 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 512
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 513 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 572
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 573 LMSAFRKGHVKVVQYLVKEVN 593
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 273 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 332
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 333 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 387
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 388 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 446
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 447 RAEVVSLLLDRKANVEHRAKTGLTPL 472
Score = 43.6 bits (98), Expect = 0.002
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 9/154 (5%)
Query: 40 GFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDT 99
G + + +YLL SGA+V A G+ + A + D+ V+ + G D +K ++ T
Sbjct: 7 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVAD-VLLQAGADLDKQE--DMKT 63
Query: 100 LMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLL-EDCNADPDCVDYEGWTP 158
++ + + A H + + + G TPL AA G++ + L+ + N + + + T
Sbjct: 64 IL-EGIDPAKH---QEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANND-HTV 118
Query: 159 LHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
+ A G LLL GADP + G T L
Sbjct: 119 VSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 152
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 292 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 350
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 351 LLLARGANKEHRNVSDYTPLSL 372
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAV 58
AC +L +VE L+ HGAD +G T L A G ++ YLL+ +V +V
Sbjct: 122 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSV 177
Score = 34.3 bits (75), Expect = 1.2
Identities = 18/55 (32%), Positives = 31/55 (56%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADV 55
M A + +L++V++L+ GA+V+ G T L G +A LL++GAD+
Sbjct: 1 MEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 55
Score = 33.9 bits (74), Expect = 1.6
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGD-NEGWTPLHATASCGFISIARYLLESGADVAAVN 59
M A +L V+FL++ GA+VNR N T + + G +++ LL GAD
Sbjct: 86 MKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRL 145
Query: 60 YDGELPVDIAESDAMADLLQKVID 83
DG + A +++ ++D
Sbjct: 146 KDGSTMLIEAAKGGHTNVVSYLLD 169
>AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containing
SOCS box protein 7 protein.
Length = 318
Score = 62.1 bits (144), Expect = 5e-09
Identities = 44/143 (30%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 22 VNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKV 81
+N N+GWTPLH A G S R LLE A+V ++ G P+ +A + ++ +
Sbjct: 110 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL 169
Query: 82 IDEK-GVDCEKS---RNAEVDTLMSDAREWALHGY-VEVRDLKTGGTPLHVAAAKGYIDV 136
+D +D + R A + + S R + G + L+ G TPLH++A + +
Sbjct: 170 LDHNANIDIQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLC 229
Query: 137 AKTLLEDCNADPDCVDYEGWTPL 159
A+ +L + AD + +YEG TPL
Sbjct: 230 AR-MLYNYGADTNTRNYEGQTPL 251
Score = 50.4 bits (115), Expect = 2e-05
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 115 VRDLKTGGTPLHVAAAKGYIDVAKTLLE-DCNADP-DCVDYEGWTPLHAAALWGQKEAAA 172
V+DL G T LH AA G +A+ +LE + +D + +GWTPLH AA +G+
Sbjct: 75 VKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVR 134
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL+F A+ + G T L L
Sbjct: 135 LLLEFKAEVDPLSDKGTTPLQL 156
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/70 (37%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNE-GWTPLHATASCGFISIARYLLESGADVAAVNYD 61
A I N + GAD N G E G TPLH +A + AR L GAD NY+
Sbjct: 187 AVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYE 246
Query: 62 GELPVDIAES 71
G+ P+ ++ S
Sbjct: 247 GQTPLAVSIS 256
Score = 41.1 bits (92), Expect = 0.011
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 125 LHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLK 184
+ A A G + + +LE P+ D GWT LH +A G++ + L+ GADP +K
Sbjct: 18 IQAAVAAGDVHTVRKMLEQ-GYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVK 76
Query: 185 NYSG 188
+ G
Sbjct: 77 DLIG 80
Score = 36.7 bits (81), Expect = 0.23
Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 12 VEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YDGELPVDIAE 70
V ++ G N D GWT LH +A+ G R LE GAD + G + A
Sbjct: 30 VRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAA 89
Query: 71 SDAMADLLQKVID-EKGVDCEKSRNAEVDTLMSDAREWALHGYV--------EVRDLK-T 120
A + + +++ E D +++ + T + A + +V EV L
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 121 GGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGAD 180
G TPL +A + K LL D NA+ +D + L A + + L+ GAD
Sbjct: 150 GTTPLQLAIIRERSSCVKILL-DHNAN---IDIQNGFLLRYAVIKSNHSYCRMFLQRGAD 205
Query: 181 PHL-KNYSGQTCLDL 194
+L + GQT L L
Sbjct: 206 TNLGRLEDGQTPLHL 220
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 62.1 bits (144), Expect = 5e-09
Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 26/261 (9%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYD- 61
AC ++V+ L+ GA+ + +TPL AS G+++I + LL +GA++ +
Sbjct: 206 ACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSK 265
Query: 62 -GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWA-LHGYVEVRDL- 118
G P+ +A + ++ ++D G D NA+++T + A A G EV L
Sbjct: 266 LGISPLMLAAMNGHVPAVKLLLD-MGSDI----NAQIETNRNTALTLACFQGRAEVVSLL 320
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLE---DCNADPDCVDYEGWTPLHAAAL 164
KTG TPL AA+ GY +V + LL+ D NA P V T L AA
Sbjct: 321 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPP--VPSSRDTALTIAAD 378
Query: 165 WGQKEAAALLLKFGADPHLKNYSGQTCLDLVDPSISSWLEEAALKAPRRVN-NNKRKLSP 223
G + LL+ GA ++N G T L L + + ++A V+ + RK++P
Sbjct: 379 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 438
Query: 224 PRHEVKRIDIEIKGQAEKIVN 244
++ +++ K VN
Sbjct: 439 LMSAFRKGHVKVVQYLVKEVN 459
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 22/206 (10%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN-YD 61
AC + ++V L+ A + D +G+TPL A+ G + + LL+ G D+ A +
Sbjct: 139 ACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERT 198
Query: 62 GELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDL--- 118
+ P+ +A S +++ ++ +G + ++ RN T +S A A GYV + +
Sbjct: 199 KDTPLSLACSGGRQEVVDLLL-ARGAN-KEHRNVSDYTPLSLA---ASGGYVNIIKILLN 253
Query: 119 -----------KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC-VDYEGWTPLHAAALWG 166
K G +PL +AA G++ K LL D +D + ++ T L A G
Sbjct: 254 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLL-DMGSDINAQIETNRNTALTLACFQG 312
Query: 167 QKEAAALLLKFGADPHLKNYSGQTCL 192
+ E +LLL A+ + +G T L
Sbjct: 313 RAEVVSLLLDRKANVEHRAKTGLTPL 338
Score = 41.1 bits (92), Expect = 0.011
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
+E RD K G TPL +AA G++ V + LL+ + TPL A G++E
Sbjct: 158 IEHRD-KKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVD 216
Query: 173 LLLKFGADPHLKNYSGQTCLDL 194
LLL GA+ +N S T L L
Sbjct: 217 LLLARGANKEHRNVSDYTPLSL 238
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 62.1 bits (144), Expect = 5e-09
Identities = 58/233 (24%), Positives = 99/233 (42%), Gaps = 13/233 (5%)
Query: 19 GADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLL 78
GA + D+EG T H A+ G + R ++ G DV A + G + +A ++ + +
Sbjct: 52 GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 111
Query: 79 QKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGY---------VEVRDLKTGGTPLHVAA 129
+K++ K E ++ L A + L + ++DL G PL +A
Sbjct: 112 RKLLQSK-CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLD-GNIPLLLAV 169
Query: 130 AKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQ 189
G+ ++ LL D AD + + G T L A G A L+K GAD +L + G
Sbjct: 170 QNGHSEICHFLL-DHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGY 228
Query: 190 TCLDLVDPSISSWLEEAALKAPRRVNNNKRKLSPPRH-EVKRIDIEIKGQAEK 241
L S ++ ++ L + + K P +H +V +I E G +K
Sbjct: 229 NALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKK 281
>BC006505-1|AAH06505.1| 282|Homo sapiens acyl-Coenzyme A binding
domain containing 6 protein.
Length = 282
Score = 61.7 bits (143), Expect = 7e-09
Identities = 30/78 (38%), Positives = 46/78 (58%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ H AD+N DNEG T LH ++C F+ I LL+SGAD + DG
Sbjct: 199 ACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
Query: 63 ELPVDIAESDAMADLLQK 80
LP ++ ++ +LQ+
Sbjct: 259 CLPEEVTGCKTVSLVLQR 276
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V+D + G LH A +G+ ++ LL+ AD +C D EG T LH A+ +
Sbjct: 185 VNVKD-EEGRALLHWACDRGHKELVTVLLQH-RADINCQDNEGQTALHYASACEFLDIVE 242
Query: 173 LLLKFGADPHLKNYSG 188
LLL+ GADP L++ G
Sbjct: 243 LLLQSGADPTLRDQDG 258
Score = 35.9 bits (79), Expect = 0.40
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 4 CIDDNLDMV-EFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
C ++N+D + + + + DVN D EG LH G + LL+ AD+ + +G
Sbjct: 166 CRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEG 225
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ + A + D+++ ++ + G D
Sbjct: 226 QTALHYASACEFLDIVELLL-QSGAD 250
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
ID ++ N D + D EG LH A G KE +LL+ AD + ++ GQT L
Sbjct: 171 IDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229
>BC001244-1|AAH01244.1| 252|Homo sapiens ASB9 protein protein.
Length = 252
Score = 61.7 bits (143), Expect = 7e-09
Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 6/183 (3%)
Query: 15 LVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAM 74
L++ G VN + +PLH G +S + LL+ GA V V D P+ A
Sbjct: 55 LISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGS 114
Query: 75 ADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYI 134
D + ++ + G + +++ + + +A A G ++ + + GTPL++A
Sbjct: 115 WDCVNLLL-QHGASVQPE--SDLASPIHEAARRAYGGNIDHK-ISHLGTPLYLACENQQR 170
Query: 135 DVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCLDL 194
K LLE AD + + +PLHA A +E A LL+ FGAD KN G+ ++L
Sbjct: 171 ACVKKLLES-GADVNQGKGQD-SPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 228
Query: 195 VDP 197
V P
Sbjct: 229 VPP 231
Score = 49.2 bits (112), Expect = 4e-05
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + V+ L+ GADVN+G + +PLHA A +A L++ GAD A N +G
Sbjct: 164 ACENQQRACVKKLLESGADVNQGKGQD-SPLHAVARTASEELACLLMDFGADTQAKNAEG 222
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSR 93
+ PV++ + + L Q ++ +G K +
Sbjct: 223 KRPVELVPPE--SPLAQLFLEREGASLPKPK 251
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/161 (27%), Positives = 63/161 (39%), Gaps = 14/161 (8%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC+ +L V+ L+ HGA VN + TPL G LL+ GA V + D
Sbjct: 76 ACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPES-DL 134
Query: 63 ELPVDIAESDAMADLLQKVIDEKG----VDCEKSRNAEVDTLMSDAREWALHGYVEVRDL 118
P+ A A + I G + CE + A V L+ +V
Sbjct: 135 ASPIHEAARRAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG--------ADVNQG 186
Query: 119 KTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPL 159
K +PLH A ++A LL D AD + EG P+
Sbjct: 187 KGQDSPLHAVARTASEELA-CLLMDFGADTQAKNAEGKRPV 226
>AL445469-1|CAH71747.1| 282|Homo sapiens acyl-Coenzyme A binding
domain containing 6 protein.
Length = 282
Score = 61.7 bits (143), Expect = 7e-09
Identities = 30/78 (38%), Positives = 46/78 (58%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ H AD+N DNEG T LH ++C F+ I LL+SGAD + DG
Sbjct: 199 ACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
Query: 63 ELPVDIAESDAMADLLQK 80
LP ++ ++ +LQ+
Sbjct: 259 CLPEEVTGCKTVSLVLQR 276
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V+D + G LH A +G+ ++ LL+ AD +C D EG T LH A+ +
Sbjct: 185 VNVKD-EEGRALLHWACDRGHKELVTVLLQH-RADINCQDNEGQTALHYASACEFLDIVE 242
Query: 173 LLLKFGADPHLKNYSG 188
LLL+ GADP L++ G
Sbjct: 243 LLLQSGADPTLRDQDG 258
Score = 35.9 bits (79), Expect = 0.40
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 4 CIDDNLDMV-EFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
C ++N+D + + + + DVN D EG LH G + LL+ AD+ + +G
Sbjct: 166 CRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEG 225
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ + A + D+++ ++ + G D
Sbjct: 226 QTALHYASACEFLDIVELLL-QSGAD 250
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
ID ++ N D + D EG LH A G KE +LL+ AD + ++ GQT L
Sbjct: 171 IDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229
>AL358354-1|CAI15093.1| 282|Homo sapiens acyl-Coenzyme A binding
domain containing 6 protein.
Length = 282
Score = 61.7 bits (143), Expect = 7e-09
Identities = 30/78 (38%), Positives = 46/78 (58%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ H AD+N DNEG T LH ++C F+ I LL+SGAD + DG
Sbjct: 199 ACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
Query: 63 ELPVDIAESDAMADLLQK 80
LP ++ ++ +LQ+
Sbjct: 259 CLPEEVTGCKTVSLVLQR 276
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V+D + G LH A +G+ ++ LL+ AD +C D EG T LH A+ +
Sbjct: 185 VNVKD-EEGRALLHWACDRGHKELVTVLLQH-RADINCQDNEGQTALHYASACEFLDIVE 242
Query: 173 LLLKFGADPHLKNYSG 188
LLL+ GADP L++ G
Sbjct: 243 LLLQSGADPTLRDQDG 258
Score = 35.9 bits (79), Expect = 0.40
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 4 CIDDNLDMV-EFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
C ++N+D + + + + DVN D EG LH G + LL+ AD+ + +G
Sbjct: 166 CRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEG 225
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ + A + D+++ ++ + G D
Sbjct: 226 QTALHYASACEFLDIVELLL-QSGAD 250
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
ID ++ N D + D EG LH A G KE +LL+ AD + ++ GQT L
Sbjct: 171 IDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229
>AL139141-2|CAI19365.1| 282|Homo sapiens acyl-Coenzyme A binding
domain containing 6 protein.
Length = 282
Score = 61.7 bits (143), Expect = 7e-09
Identities = 30/78 (38%), Positives = 46/78 (58%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
AC + ++V L+ H AD+N DNEG T LH ++C F+ I LL+SGAD + DG
Sbjct: 199 ACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDG 258
Query: 63 ELPVDIAESDAMADLLQK 80
LP ++ ++ +LQ+
Sbjct: 259 CLPEEVTGCKTVSLVLQR 276
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 113 VEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAA 172
V V+D + G LH A +G+ ++ LL+ AD +C D EG T LH A+ +
Sbjct: 185 VNVKD-EEGRALLHWACDRGHKELVTVLLQH-RADINCQDNEGQTALHYASACEFLDIVE 242
Query: 173 LLLKFGADPHLKNYSG 188
LLL+ GADP L++ G
Sbjct: 243 LLLQSGADPTLRDQDG 258
Score = 35.9 bits (79), Expect = 0.40
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 4 CIDDNLDMV-EFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
C ++N+D + + + + DVN D EG LH G + LL+ AD+ + +G
Sbjct: 166 CRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEG 225
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVD 88
+ + A + D+++ ++ + G D
Sbjct: 226 QTALHYASACEFLDIVELLL-QSGAD 250
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 134 IDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
ID ++ N D + D EG LH A G KE +LL+ AD + ++ GQT L
Sbjct: 171 IDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTAL 229
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 200
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 201 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 236
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 237 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 296
Query: 182 HL 183
L
Sbjct: 297 SL 298
Score = 58.4 bits (135), Expect = 7e-08
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +++ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 179
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 234
Score = 44.8 bits (101), Expect = 9e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 82 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADIQQVGYGGLTALHI 140
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQD 164
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 311 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 370
Query: 60 YD 61
D
Sbjct: 371 CD 372
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 200
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 201 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 236
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 237 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 296
Query: 182 HL 183
L
Sbjct: 297 SL 298
Score = 58.4 bits (135), Expect = 7e-08
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +++ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 179
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 234
Score = 44.8 bits (101), Expect = 9e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 82 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADIQQVGYGGLTALHI 140
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQD 164
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 311 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 370
Query: 60 YD 61
D
Sbjct: 371 CD 372
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 200
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 201 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 236
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 237 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 296
Query: 182 HL 183
L
Sbjct: 297 SL 298
Score = 58.4 bits (135), Expect = 7e-08
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +++ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 179
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 234
Score = 44.8 bits (101), Expect = 9e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 82 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADIQQVGYGGLTALHI 140
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQD 164
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 311 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 370
Query: 60 YD 61
D
Sbjct: 371 CD 372
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 200
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 201 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 236
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 237 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 296
Query: 182 HL 183
L
Sbjct: 297 SL 298
Score = 58.4 bits (135), Expect = 7e-08
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +++ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 179
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 234
Score = 44.8 bits (101), Expect = 9e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 82 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADIQQVGYGGLTALHI 140
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQD 164
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 311 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 370
Query: 60 YD 61
D
Sbjct: 371 CD 372
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 242 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 301
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 302 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 337
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 338 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 397
Query: 182 HL 183
L
Sbjct: 398 SL 399
Score = 58.8 bits (136), Expect = 5e-08
Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +V+ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 222 LHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 280
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 281 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 335
Score = 45.2 bits (102), Expect = 7e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 183 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADVQQVGYGGLTALHI 241
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 242 ATIAGHLEAADVLLQHGANVNIQD 265
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 412 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 471
Query: 60 YD 61
D
Sbjct: 472 CD 473
>BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein.
Length = 716
Score = 61.3 bits (142), Expect = 9e-09
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 28/203 (13%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESG-ADVAAVN 59
M A +++L+ V++L+ GA V+ D EG T LH A G + +YLL +G DV +
Sbjct: 229 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQD 288
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
G P+ A DL+ K++ KG D + +RD
Sbjct: 289 DGGWTPMIWATEYKHVDLV-KLLLSKGSD------------------------INIRD-N 322
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
LH AA G +D+A+ LL D V+ G +PLH AA + + L L +
Sbjct: 323 EENICLHWAAFSGCVDIAEILLA-AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDS 381
Query: 180 DPHLKNYSGQTCLDLVDPSISSW 202
D LKN G+T L + W
Sbjct: 382 DVTLKNKEGETPLQCASLNSQVW 404
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 26/162 (16%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
+PLHA A G + I L+++GA++ + D P+ E
Sbjct: 193 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPL----------------------ME 230
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
+ N ++ + + AL V+ +D + G T LH+AA KG+ +V + LL + D +C
Sbjct: 231 AAENNHLEAVKYLIKAGAL---VDPKDAE-GSTCLHLAAKKGHYEVVQYLLSNGQMDVNC 286
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D GWTP+ A + + LLL G+D ++++ CL
Sbjct: 287 QDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICL 328
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 61.3 bits (142), Expect = 9e-09
Identities = 51/182 (28%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 3 ACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVNYDG 62
A I +L+ + L+ HGA+VN D +TPLH A G + R LL+ GADV G
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVG 200
Query: 63 ELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLKTGG 122
+ P+ +A + ++ + +++E ++ D D + H
Sbjct: 201 DRPLHLASAKGFLNIAKLLMEE---------GSKADVNAQDNED---H------------ 236
Query: 123 TPLHVAAAKGYIDVAKTLLE-DCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGADP 181
PLH + G+ D+ K LL+ D P V+ G TPLH A G+ E A +++
Sbjct: 237 VPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTE 296
Query: 182 HL 183
L
Sbjct: 297 SL 298
Score = 58.4 bits (135), Expect = 7e-08
Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 6/115 (5%)
Query: 109 LHGYVEVRDLKTGG-TPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQ 167
LH +++ + GG T LH+A G+++ A LL+ A+ + D +TPLH AA +G
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQH-GANVNIQDAVFFTPLHIAAYYGH 179
Query: 168 KEAAALLLKFGADPHLKNYSGQTCLDLVDP----SISSWLEEAALKAPRRVNNNK 218
++ LLLKFGAD ++ G L L +I+ L E KA +N+
Sbjct: 180 EQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNE 234
Score = 44.8 bits (101), Expect = 9e-04
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 102 SDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHA 161
S R L G R + G T LH+A K ++ +LL AD V Y G T LH
Sbjct: 82 SHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHS-GADIQQVGYGGLTALHI 140
Query: 162 AALWGQKEAAALLLKFGADPHLKN 185
A + G EAA +LL+ GA+ ++++
Sbjct: 141 ATIAGHLEAADVLLQHGANVNIQD 164
Score = 39.1 bits (87), Expect = 0.043
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 2 SACI-DDNLDMVEFLVTHGA-DVNRGDNEGWTPLHATASCGFISIARYLLESGADVAAVN 59
SAC ++D+V+FL+ ++N +G T LH+ G I + ++LL++GAD+ V
Sbjct: 311 SACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVA 370
Query: 60 YD 61
D
Sbjct: 371 CD 372
>AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone
methyltransferase 1 protein.
Length = 1267
Score = 61.3 bits (142), Expect = 9e-09
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 28/203 (13%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESG-ADVAAVN 59
M A +++L+ V++L+ GA V+ D EG T LH A G + +YLL +G DV +
Sbjct: 780 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQD 839
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
G P+ A DL+ K++ KG D + +RD
Sbjct: 840 DGGWTPMIWATEYKHVDLV-KLLLSKGSD------------------------INIRD-N 873
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
LH AA G +D+A+ LL D V+ G +PLH AA + + L L +
Sbjct: 874 EENICLHWAAFSGCVDIAEILLA-AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDS 932
Query: 180 DPHLKNYSGQTCLDLVDPSISSW 202
D LKN G+T L + W
Sbjct: 933 DVTLKNKEGETPLQCASLNSQVW 955
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 26/162 (16%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
+PLHA A G + I L+++GA++ + D P+ E
Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPL----------------------ME 781
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
+ N ++ + + AL V+ +D + G T LH+AA KG+ +V + LL + D +C
Sbjct: 782 AAENNHLEAVKYLIKAGAL---VDPKDAE-GSTCLHLAAKKGHYEVVQYLLSNGQMDVNC 837
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D GWTP+ A + + LLL G+D ++++ CL
Sbjct: 838 QDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICL 879
>AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 61.3 bits (142), Expect = 9e-09
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 28/203 (13%)
Query: 1 MSACIDDNLDMVEFLVTHGADVNRGDNEGWTPLHATASCGFISIARYLLESG-ADVAAVN 59
M A +++L+ V++L+ GA V+ D EG T LH A G + +YLL +G DV +
Sbjct: 780 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQD 839
Query: 60 YDGELPVDIAESDAMADLLQKVIDEKGVDCEKSRNAEVDTLMSDAREWALHGYVEVRDLK 119
G P+ A DL+ K++ KG D + +RD
Sbjct: 840 DGGWTPMIWATEYKHVDLV-KLLLSKGSD------------------------INIRD-N 873
Query: 120 TGGTPLHVAAAKGYIDVAKTLLEDCNADPDCVDYEGWTPLHAAALWGQKEAAALLLKFGA 179
LH AA G +D+A+ LL D V+ G +PLH AA + + L L +
Sbjct: 874 EENICLHWAAFSGCVDIAEILLA-AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDS 932
Query: 180 DPHLKNYSGQTCLDLVDPSISSW 202
D LKN G+T L + W
Sbjct: 933 DVTLKNKEGETPLQCASLNSQVW 955
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 26/162 (16%)
Query: 31 TPLHATASCGFISIARYLLESGADVAAVNYDGELPVDIAESDAMADLLQKVIDEKGVDCE 90
+PLHA A G + I L+++GA++ + D P+ E
Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPL----------------------ME 781
Query: 91 KSRNAEVDTLMSDAREWALHGYVEVRDLKTGGTPLHVAAAKGYIDVAKTLLEDCNADPDC 150
+ N ++ + + AL V+ +D + G T LH+AA KG+ +V + LL + D +C
Sbjct: 782 AAENNHLEAVKYLIKAGAL---VDPKDAE-GSTCLHLAAKKGHYEVVQYLLSNGQMDVNC 837
Query: 151 VDYEGWTPLHAAALWGQKEAAALLLKFGADPHLKNYSGQTCL 192
D GWTP+ A + + LLL G+D ++++ CL
Sbjct: 838 QDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICL 879
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.127 0.362
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,864,352
Number of Sequences: 224733
Number of extensions: 2858075
Number of successful extensions: 17879
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 925
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 7815
Number of HSP's gapped (non-prelim): 5980
length of query: 589
length of database: 73,234,838
effective HSP length: 94
effective length of query: 495
effective length of database: 52,109,936
effective search space: 25794418320
effective search space used: 25794418320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 68 (31.5 bits)
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