Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002004-TA|BGIBMGA002004-PA|IPR003439|ABC transporter
related, IPR003593|AAA ATPase
(622 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette, s... 863 0.0
BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette, s... 863 0.0
AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC tran... 863 0.0
AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC tran... 863 0.0
AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein. 863 0.0
AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein. 863 0.0
AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein. 858 0.0
BC051884-1|AAH51884.2| 709|Homo sapiens ATP-binding cassette, s... 429 e-119
BC051754-1|AAH51754.1| 709|Homo sapiens ATP-binding cassette, s... 429 e-119
BC009253-1|AAH09253.1| 709|Homo sapiens ATP-binding cassette, s... 429 e-119
AK002060-1|BAA92063.1| 709|Homo sapiens protein ( Homo sapiens ... 429 e-119
AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens ... 425 e-118
BX248518-7|CAM26017.1| 845|Homo sapiens ATP-binding cassette su... 402 e-111
BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette su... 402 e-111
BX119957-3|CAM25907.1| 845|Homo sapiens ATP-binding cassette su... 402 e-111
BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette su... 402 e-111
BX000357-8|CAI18563.1| 845|Homo sapiens ATP-binding cassette, s... 402 e-111
BX000357-6|CAI18562.1| 807|Homo sapiens ATP-binding cassette, s... 402 e-111
BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette, s... 402 e-111
BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette, s... 402 e-111
BA000025-75|BAB63325.1| 807|Homo sapiens TNFalpha-inducible ATP... 402 e-111
AL662825-8|CAI17836.1| 807|Homo sapiens ATP-binding cassette, s... 402 e-111
AL662825-7|CAI17837.1| 845|Homo sapiens ATP-binding cassette, s... 402 e-111
AL662800-8|CAI18158.1| 845|Homo sapiens ATP-binding cassette, s... 402 e-111
AL662800-7|CAI18159.1| 807|Homo sapiens ATP-binding cassette, s... 402 e-111
AF027302-1|AAC70891.1| 807|Homo sapiens TNF-alpha stimulated AB... 402 e-111
AB209564-1|BAD92801.1| 593|Homo sapiens ATP-binding cassette, s... 402 e-111
AB202093-1|BAE78612.1| 807|Homo sapiens ATP-binding cassette, s... 402 e-111
AB103602-1|BAF31263.1| 807|Homo sapiens ABC50 protein protein. 402 e-111
AB088096-1|BAC54928.1| 807|Homo sapiens ATP-binding cassette, s... 402 e-111
AK024758-1|BAB14989.1| 390|Homo sapiens protein ( Homo sapiens ... 326 1e-88
BX248518-8|CAM26018.1| 238|Homo sapiens ATP-binding cassette su... 107 1e-22
BX119957-4|CAM25908.1| 238|Homo sapiens ATP-binding cassette su... 107 1e-22
BX000357-7|CAM25770.1| 238|Homo sapiens ATP-binding cassette, s... 107 1e-22
AL662825-6|CAM25037.1| 238|Homo sapiens ATP-binding cassette, s... 107 1e-22
AL662800-6|CAI18157.2| 238|Homo sapiens ATP-binding cassette, s... 107 1e-22
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein. 60 3e-08
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein. 60 3e-08
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s... 60 3e-08
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s... 60 3e-08
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein. 60 3e-08
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr... 60 3e-08
AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens ... 57 2e-07
BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette, s... 56 3e-07
AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette, s... 56 3e-07
AK172794-1|BAD18770.1| 433|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein. 56 3e-07
AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette pr... 55 7e-07
AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5... 55 9e-07
AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens ... 55 9e-07
AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein. 55 9e-07
X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA) p... 54 1e-06
EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette, s... 54 1e-06
BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette, s... 54 1e-06
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ... 54 2e-06
AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding casset... 54 2e-06
BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette, s... 52 5e-06
BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette, s... 52 5e-06
AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5 pr... 52 5e-06
AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein. 52 5e-06
AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein. 52 5e-06
AF319622-1|AAN76500.1| 681|Homo sapiens P-glycoprotein protein. 52 5e-06
X87344-5|CAA60785.1| 748|Homo sapiens TAP1 protein. 52 6e-06
X66401-2|CAA47025.1| 748|Homo sapiens ABC-transporter protein. 52 6e-06
X57522-1|CAA40741.1| 808|Homo sapiens peptide transporter protein. 52 6e-06
L21208-1|AAC12906.1| 748|Homo sapiens peptide transporter protein. 52 6e-06
L21204-1|AAC12902.1| 748|Homo sapiens peptide transporter protein. 52 6e-06
BX088556-4|CAM26263.1| 808|Homo sapiens transporter 1 ATP-bindi... 52 6e-06
BC014081-1|AAH14081.1| 808|Homo sapiens transporter 1, ATP-bind... 52 6e-06
AL935043-6|CAI18626.1| 808|Homo sapiens transporter 1, ATP-bind... 52 6e-06
AL671681-12|CAI17714.1| 808|Homo sapiens transporter 1, ATP-bin... 52 6e-06
AL669918-8|CAI18140.1| 808|Homo sapiens transporter 1, ATP-bind... 52 6e-06
U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette prot... 52 8e-06
AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant p... 52 8e-06
L21206-1|AAC12904.1| 748|Homo sapiens peptide transporter protein. 51 1e-05
L21205-1|AAC12903.1| 748|Homo sapiens peptide transporter protein. 51 1e-05
AY523971-1|AAS55412.1| 748|Homo sapiens TAP1 protein. 51 1e-05
AY523970-1|AAS55411.1| 748|Homo sapiens TAP1 protein. 51 1e-05
AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2 p... 50 2e-05
BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein. 50 2e-05
AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette tr... 50 2e-05
AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug resistance-as... 50 2e-05
AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette, s... 50 2e-05
AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette, s... 50 2e-05
AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette, s... 50 2e-05
AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette pr... 50 2e-05
AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B ... 50 2e-05
AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B ... 50 2e-05
L21207-1|AAC12905.1| 748|Homo sapiens peptide transporter protein. 50 3e-05
BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette, s... 50 3e-05
BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein. 50 3e-05
AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein. 50 3e-05
AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette, ... 50 3e-05
AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette, ... 50 3e-05
AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein pr... 50 3e-05
AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette, s... 50 3e-05
AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2 p... 50 3e-05
AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette su... 50 3e-05
AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette pr... 50 3e-05
AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein. 50 3e-05
Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein. 49 6e-05
U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette tran... 49 6e-05
AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter pro... 49 6e-05
AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein p... 49 6e-05
AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subf... 48 7e-05
AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette tr... 48 7e-05
AL359813-2|CAI23217.1| 1492|Homo sapiens ATP-binding cassette, s... 48 7e-05
AK000002-1|BAA92227.1| 1513|Homo sapiens FLJ00002 protein protein. 48 7e-05
AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette tr... 48 7e-05
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 48 1e-04
AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 48 1e-04
AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette tr... 48 1e-04
M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis transmemb... 47 2e-04
M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic fi... 47 2e-04
DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
AY032599-1|AAK39642.1| 1463|Homo sapiens multidrug resistance-as... 47 2e-04
AK074738-1|BAC11171.1| 472|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF216494-1|AAF89993.1| 766|Homo sapiens ATP-binding cassette pr... 47 2e-04
AF061324-1|AAC16058.1| 1549|Homo sapiens sulfonylurea receptor 2... 47 2e-04
AF061323-1|AAC16057.1| 1549|Homo sapiens sulfonylurea receptor 2... 47 2e-04
AB177852-1|BAD66830.1| 796|Homo sapiens KIAA1520 splice variant... 47 2e-04
AB045381-1|BAA97989.2| 766|Homo sapiens TAPL protein. 47 2e-04
AB040953-1|BAA96044.2| 810|Homo sapiens KIAA1520 protein protein. 47 2e-04
DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis transme... 47 2e-04
AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette su... 47 2e-04
AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette su... 47 2e-04
AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A1... 47 2e-04
AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette su... 47 2e-04
AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette su... 47 2e-04
AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6 p... 47 2e-04
AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6 p... 47 2e-04
AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein. 47 2e-04
BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein. 46 3e-04
BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein. 46 3e-04
BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein. 46 3e-04
BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette, s... 46 3e-04
AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6... 46 3e-04
AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens ... 46 3e-04
AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat pr... 46 3e-04
AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette ha... 46 3e-04
AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter prot... 46 3e-04
AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein. 46 3e-04
AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC trans... 46 3e-04
X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein. 46 4e-04
U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein. 46 4e-04
DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette, s... 46 4e-04
BC141836-1|AAI41837.1| 693|Homo sapiens Unknown (protein for MG... 46 4e-04
AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9... 46 4e-04
AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein p... 46 4e-04
AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane ... 46 4e-04
BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein. 46 5e-04
BC064384-1|AAH64384.1| 769|Homo sapiens ABCB9 protein protein. 46 5e-04
AB112583-1|BAC98410.1| 681|Homo sapiens TAP-Like isoform 12C pr... 46 5e-04
AB112582-1|BAC98409.1| 683|Homo sapiens TAP-Like isoform 12B pr... 46 5e-04
AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein. 46 5e-04
AB209084-1|BAD92321.1| 1011|Homo sapiens Sulfonylurea receptor 1... 45 7e-04
X91249-1|CAA62631.1| 674|Homo sapiens white protein. 45 0.001
U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein. 45 0.001
BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette, s... 45 0.001
AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette tr... 45 0.001
AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog (... 45 0.001
AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens ... 45 0.001
AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette tr... 45 0.001
AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette tr... 45 0.001
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 45 0.001
AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein. 45 0.001
AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein. 45 0.001
U63455-1|AAB36700.1| 1581|Homo sapiens sulfonylurea receptor pro... 44 0.001
U63421-1|AAB36699.1| 1581|Homo sapiens sulfonylurea receptor pro... 44 0.001
L78243-2|AAB02418.1| 1582|Homo sapiens SUR1 protein. 44 0.001
L78243-1|AAB02417.1| 1581|Homo sapiens SUR1 protein. 44 0.001
L78207-1|AAB02278.1| 1581|Homo sapiens sulfonylurea receptor pro... 44 0.001
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 44 0.001
AF087138-1|AAC36724.1| 1581|Homo sapiens sulfonylurea receptor 1... 44 0.001
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 44 0.001
Z31348-1|CAA83230.1| 745|Homo sapiens adrenoleukodystropy protein. 44 0.002
Z21876-1|CAA79922.1| 745|Homo sapiens ALD protein (ALDP) protein. 44 0.002
X58528-1|CAA41416.1| 659|Homo sapiens 70kDa peroxisomal membran... 44 0.002
BC025358-1|AAH25358.1| 745|Homo sapiens ATP-binding cassette, s... 44 0.002
BC015541-1|AAH15541.1| 745|Homo sapiens ATP-binding cassette, s... 44 0.002
AK223300-1|BAD97020.1| 703|Homo sapiens transporter 2, ATP-bind... 44 0.002
AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens ... 44 0.002
Z22935-1|CAA80522.1| 703|Homo sapiens TAP2B protein. 43 0.003
X87344-8|CAA60788.1| 686|Homo sapiens TAP2 protein. 43 0.003
X66401-4|CAA47027.1| 686|Homo sapiens TAP2 protein. 43 0.003
U18236-1|AAA84437.2| 131|Homo sapiens ATP-binding cassette prot... 43 0.003
M74447-1|AAA59841.1| 703|Homo sapiens PSF-2 protein. 43 0.003
BX682530-4|CAI41935.1| 703|Homo sapiens transporter 2 ATP-bindi... 43 0.003
BT009906-1|AAP88908.1| 686|Homo sapiens transporter 2, ATP-bind... 43 0.003
BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette, s... 43 0.003
AL935043-2|CAI18622.1| 686|Homo sapiens transporter 2, ATP-bind... 43 0.003
AL671681-8|CAI17711.1| 686|Homo sapiens transporter 2, ATP-bind... 43 0.003
AL669918-4|CAI18137.1| 686|Homo sapiens transporter 2, ATP-bind... 43 0.003
AK222823-1|BAD96543.1| 703|Homo sapiens transporter 2, ATP-bind... 43 0.003
AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein. 43 0.003
AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein. 43 0.003
AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein. 43 0.003
AF176984-1|AAD50509.1| 372|Homo sapiens TAP2 protein protein. 43 0.003
AF136750-1|AAD23601.1| 483|Homo sapiens TAP2 protein protein. 43 0.003
AF100418-1|AAD23381.1| 483|Homo sapiens TAP2 protein protein. 43 0.003
AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein. 43 0.003
AB208953-1|BAD92190.1| 704|Homo sapiens transporter 2, ATP-bind... 43 0.003
M81182-1|AAA60128.1| 659|Homo sapiens 70kDa peroxisomal membran... 43 0.004
BC068509-1|AAH68509.1| 549|Homo sapiens ABCD3 protein protein. 43 0.004
AL138758-1|CAC15960.2| 659|Homo sapiens ATP-binding cassette, s... 43 0.004
AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens ... 43 0.004
AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens ... 43 0.004
Z22936-1|CAA80523.1| 686|Homo sapiens TAP2E protein. 42 0.005
U07844-1|AAA79901.1| 622|Homo sapiens ABC transport protein pro... 42 0.005
DQ388136-1|ABD72199.1| 1321|Homo sapiens cystic fibrosis transme... 42 0.005
DQ356257-1|ABC87053.1| 1480|Homo sapiens cystic fibrosis transme... 42 0.005
BX682530-5|CAI41936.1| 653|Homo sapiens transporter 2 ATP-bindi... 42 0.005
BX296564-5|CAI41937.1| 653|Homo sapiens transporter 2 ATP-bindi... 42 0.005
BX248518-5|CAM26015.1| 340|Homo sapiens ATP-binding cassette su... 42 0.005
BX119957-1|CAM25905.1| 340|Homo sapiens ATP-binding cassette su... 42 0.005
BX000357-5|CAI18561.2| 340|Homo sapiens ATP-binding cassette, s... 42 0.005
AL935043-1|CAI18621.1| 653|Homo sapiens transporter 2, ATP-bind... 42 0.005
AL671681-7|CAI17710.1| 653|Homo sapiens transporter 2, ATP-bind... 42 0.005
AL669918-3|CAI18136.1| 653|Homo sapiens transporter 2, ATP-bind... 42 0.005
AL662825-5|CAI17835.2| 340|Homo sapiens ATP-binding cassette, s... 42 0.005
AL662800-5|CAI18156.2| 340|Homo sapiens ATP-binding cassette, s... 42 0.005
AF105151-1|AAD12059.1| 653|Homo sapiens Tap2 transporter isofor... 42 0.005
AF078671-1|AAD31384.1| 653|Homo sapiens transporter 2 isoform p... 42 0.005
AB073779-1|BAB71769.1| 703|Homo sapiens ABC-transporter protein. 42 0.005
BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein. 42 0.007
AY196326-1|AAO40749.1| 930|Homo sapiens truncated ABCC12 protei... 42 0.007
AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette tr... 42 0.007
AL833963-1|CAD38811.1| 453|Homo sapiens hypothetical protein pr... 42 0.007
AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette pr... 42 0.007
AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette pr... 42 0.007
AF395909-1|AAL79529.1| 935|Homo sapiens ATP-binding cassette pr... 42 0.007
AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette pr... 42 0.007
BT009918-1|AAP88920.1| 753|Homo sapiens ATP-binding cassette, s... 42 0.009
BC006323-1|AAH06323.1| 753|Homo sapiens ATP-binding cassette, s... 42 0.009
AL360179-2|CAH70565.1| 752|Homo sapiens ATP-binding cassette, s... 42 0.009
AL360179-1|CAH70564.1| 753|Homo sapiens ATP-binding cassette, s... 42 0.009
AL359545-2|CAI41573.1| 752|Homo sapiens ATP-binding cassette, s... 42 0.009
AL359545-1|CAI41574.1| 753|Homo sapiens ATP-binding cassette, s... 42 0.009
AF241887-1|AAK20173.1| 752|Homo sapiens ATP binding cassette 7 ... 42 0.009
AF133659-1|AAD33045.1| 752|Homo sapiens ATP-binding cassette 7 ... 42 0.009
AB005289-1|BAA28861.1| 752|Homo sapiens ABC transporter 7 prote... 42 0.009
X83467-1|CAA58470.1| 660|Homo sapiens 70kD peroxisomal integral... 41 0.011
L05628-1|AAB46616.1| 1531|Homo sapiens multidrug resistance-asso... 41 0.011
EF419769-1|ABN79590.1| 1531|Homo sapiens ATP-binding cassette, s... 41 0.011
AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette, s... 41 0.011
AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette, s... 41 0.011
AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein. 41 0.011
AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette tr... 41 0.011
AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member ... 41 0.011
AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7 p... 41 0.011
AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1 ... 41 0.011
AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette tr... 41 0.011
AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein. 41 0.011
AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transpor... 41 0.011
AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding tr... 41 0.011
AF078777-1|AAD47141.1| 748|Homo sapiens ABC transporter protein. 41 0.011
AF022853-2|AAB83983.1| 1450|Homo sapiens multidrug resistance pr... 41 0.011
AF022853-1|AAB83979.1| 1515|Homo sapiens multidrug resistance pr... 41 0.011
AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein. 41 0.011
AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein. 41 0.011
BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette, s... 41 0.015
AY848832-1|AAW33659.1| 418|Homo sapiens cystic fibrosis transme... 40 0.020
AY848831-1|AAW33658.1| 405|Homo sapiens cystic fibrosis transme... 40 0.020
AY848829-1|AAW33656.1| 258|Homo sapiens cystic fibrosis transme... 40 0.020
AC000061-1|AAB46340.2| 484|Homo sapiens unknown protein. 40 0.020
X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug res... 40 0.026
U83661-1|AAB71758.2| 1437|Homo sapiens multidrug resistance prot... 40 0.026
U83659-1|AAB71756.1| 485|Homo sapiens multidrug resistance-asso... 40 0.026
U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific... 40 0.026
U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific... 40 0.026
AY196484-1|AAO49801.1| 1394|Homo sapiens ATP-binding cassette C5... 40 0.026
AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette, s... 40 0.026
AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette, s... 40 0.026
AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance pr... 40 0.026
AF146074-1|AAD37716.1| 1437|Homo sapiens ABC protein protein. 40 0.026
AF104942-1|AAD04169.1| 1437|Homo sapiens ABC transporter MOAT-C ... 40 0.026
AC003026-1|AAC05808.1| 691|Homo sapiens Multiple drug resistanc... 40 0.026
AB209454-1|BAD92691.1| 1430|Homo sapiens Multidrug resistance-as... 40 0.026
AB209120-1|BAD92357.1| 1439|Homo sapiens ATP-binding cassette, s... 40 0.026
AB209103-1|BAD92340.1| 799|Homo sapiens ATP-binding cassette C5... 40 0.026
AB019002-1|BAA76608.1| 1437|Homo sapiens MRP5 protein. 40 0.026
AB005659-1|BAA22887.1| 946|Homo sapiens SMRP protein. 40 0.026
U07197-1|AAB60321.1| 45|Homo sapiens TAP1 protein. 40 0.035
AY851364-1|AAW31629.1| 131|Homo sapiens ABCB5alpha protein. 40 0.035
AJ294545-1|CAC69553.1| 1514|Homo sapiens multidrug resistance as... 40 0.035
U16763-1|AAA89080.1| 44|Homo sapiens TAP1 protein. 39 0.046
BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein pr... 39 0.046
BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette, s... 39 0.046
AY040219-1|AAK76739.1| 1382|Homo sapiens ATP-binding cassette tr... 39 0.046
AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein. 39 0.046
AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein. 39 0.046
AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family A... 39 0.046
AF492485-1|AAM11658.1| 45|Homo sapiens TAP1 protein. 39 0.046
AF411579-1|AAL99902.1| 1344|Homo sapiens ATP-binding cassette pr... 39 0.046
AF367202-1|AAK58869.1| 1382|Homo sapiens ATP-binding cassette pr... 39 0.046
AF083552-1|AAC34668.1| 1527|Homo sapiens canalicular multispecif... 39 0.046
AF022853-4|AAB83981.1| 1456|Homo sapiens multidrug resistance pr... 39 0.046
Y17151-1|CAA76658.2| 1527|Homo sapiens multidrug resistance prot... 39 0.061
U91318-3|AAC15785.1| 848|Homo sapiens Gene product with similar... 39 0.061
AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens ... 39 0.061
AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic ... 39 0.061
AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding tr... 39 0.061
AF154001-1|AAD38185.1| 285|Homo sapiens MRP3s1 protein protein. 39 0.061
AF104943-1|AAD04170.1| 1527|Homo sapiens ABC transporter MOAT-D ... 39 0.061
AF085690-1|AAD02845.1| 1527|Homo sapiens multidrug resistance-as... 39 0.061
AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein. 39 0.061
AF009670-1|AAD01430.1| 1528|Homo sapiens MRP3 protein. 39 0.061
AB208954-1|BAD92191.1| 1533|Homo sapiens ATP-binding cassette, s... 39 0.061
AB010887-1|BAA28146.1| 1527|Homo sapiens multidrug resistance-as... 39 0.061
DQ148409-1|AAZ38723.1| 599|Homo sapiens ATP-binding cassette, s... 38 0.11
BT009779-1|AAP88781.1| 599|Homo sapiens ATP-binding cassette, s... 38 0.11
BC016283-1|AAH16283.1| 599|Homo sapiens ATP-binding cassette, s... 38 0.11
AB062293-1|BAB93476.1| 599|Homo sapiens ATP-binding cassette su... 38 0.11
X76388-1|CAA53972.1| 599|Homo sapiens RNase L inhibitor protein. 37 0.19
BC104903-1|AAI04904.1| 740|Homo sapiens ATP-binding cassette, s... 37 0.24
BC104901-1|AAI04902.1| 740|Homo sapiens ATP-binding cassette, s... 37 0.24
AY421738-1|AAR07958.1| 240|Homo sapiens mutant adrenoleukodystr... 37 0.24
AL080207-1|CAB45776.1| 196|Homo sapiens hypothetical protein pr... 37 0.24
AJ000327-1|CAA03994.1| 740|Homo sapiens adrenoleukodystrophy re... 37 0.24
AF119831-1|AAD30439.1| 740|Homo sapiens adrenoleukodystrophy-re... 37 0.24
AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant... 37 0.24
AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens ... 36 0.32
AF352582-1|AAK19755.1| 1382|Homo sapiens ATP-binding cassette tr... 36 0.32
AF085691-1|AAD02846.1| 1238|Homo sapiens multidrug resistance-as... 36 0.32
AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein. 36 0.32
L10287-1|AAA58649.1| 129|Homo sapiens TAP2 protein. 36 0.43
L09191-1|AAA58648.1| 129|Homo sapiens TAP2 protein. 36 0.43
AC069137-4|AAY24100.1| 451|Homo sapiens unknown protein. 36 0.43
X57521-1|CAA40740.1| 430|Homo sapiens Y3 protein. 36 0.56
DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette, s... 36 0.56
BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein. 36 0.56
BC024103-1|AAH24103.1| 282|Homo sapiens ABCC10 protein protein. 36 0.56
BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette, s... 36 0.56
AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette su... 36 0.56
AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding cass... 36 0.56
AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette su... 36 0.56
AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2 p... 36 0.56
AL359813-4|CAI23219.1| 172|Homo sapiens ATP-binding cassette, s... 36 0.56
AL133613-1|CAB63742.1| 700|Homo sapiens hypothetical protein pr... 36 0.56
AK024446-1|BAB15736.1| 706|Homo sapiens FLJ00036 protein protein. 36 0.56
AJ278917-1|CAC07210.1| 109|Homo sapiens putative ATP-binding ca... 36 0.56
AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette pr... 36 0.56
AF320293-1|AAG40003.1| 651|Homo sapiens ABCG5 protein. 36 0.56
AF312715-1|AAG53099.1| 651|Homo sapiens sterolin protein. 36 0.56
AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistanc... 36 0.56
AC108476-1|AAY24010.1| 549|Homo sapiens unknown protein. 36 0.56
AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein. 36 0.56
AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistanc... 36 0.56
AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette su... 36 0.56
AY289766-1|AAP44087.1| 655|Homo sapiens ABC transporter protein. 35 0.99
AF103796-1|AAD09188.1| 655|Homo sapiens placenta-specific ATP-b... 35 0.99
AF022853-5|AAB83982.1| 1400|Homo sapiens multidrug resistance pr... 35 0.99
AF022853-3|AAB83980.1| 1459|Homo sapiens multidrug resistance pr... 35 0.99
BC017348-1|AAH17348.1| 596|Homo sapiens ABCB9 protein protein. 34 1.3
AB012959-1|BAA88711.1| 63|Homo sapiens sister p-glycoprotein p... 34 1.7
AL359813-5|CAI23220.1| 157|Homo sapiens ATP-binding cassette, s... 33 2.3
AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein pr... 33 2.3
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 33 3.0
M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal sy... 33 4.0
BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndr... 33 4.0
BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndr... 33 4.0
AY849794-1|AAW33782.1| 159|Homo sapiens cystic fibrosis transme... 33 4.0
AY848830-1|AAW33657.1| 241|Homo sapiens cystic fibrosis transme... 33 4.0
AY848828-1|AAW33655.1| 159|Homo sapiens cystic fibrosis transme... 33 4.0
AY490254-1|AAR99172.1| 164|Homo sapiens P-glycoprotein protein. 33 4.0
AY421737-1|AAR07957.1| 240|Homo sapiens mutant adrenoleukodystr... 33 4.0
AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndr... 33 4.0
AL138745-4|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndr... 33 4.0
AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndr... 33 4.0
AJ575045-1|CAE00759.1| 58|Homo sapiens cystic fibrosis transme... 33 4.0
AJ575044-1|CAE00758.1| 58|Homo sapiens cystic fibrosis transme... 33 4.0
AJ575043-1|CAE00757.1| 58|Homo sapiens cystic fibrosis transme... 33 4.0
AJ575042-1|CAE00756.1| 58|Homo sapiens cystic fibrosis transme... 33 4.0
AJ575041-1|CAE00755.2| 58|Homo sapiens cystic fibrosis transme... 33 4.0
AF356348-1|AAL35305.1| 103|Homo sapiens breast cancer resistanc... 33 4.0
X74987-1|CAA52920.1| 402|Homo sapiens endoribonuclease protein. 32 5.3
U91318-1|AAC15784.1| 401|Homo sapiens Multiple drug resistance ... 32 5.3
BC001636-1|AAH01636.1| 316|Homo sapiens Unknown (protein for IM... 32 5.3
AB208839-1|BAD92076.1| 403|Homo sapiens ATP-binding cassette, s... 32 5.3
X95715-1|CAA65019.1| 453|Homo sapiens anthracycline resistance ... 32 7.0
U83660-1|AAB71757.1| 162|Homo sapiens multidrug resistance-asso... 31 9.2
BC086308-1|AAH86308.1| 835|Homo sapiens NBPF8 protein protein. 31 9.2
>BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC
transporter 1 protein.
Length = 623
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC
transporter 2 protein.
Length = 623
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein.
Length = 623
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein.
Length = 634
Score = 863 bits (2136), Expect = 0.0
Identities = 397/545 (72%), Positives = 461/545 (84%), Gaps = 2/545 (0%)
Query: 68 ARSCTGSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLA 127
AR+ TG LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+
Sbjct: 70 ARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLS 129
Query: 128 ALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQE 187
A+G+REVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E
Sbjct: 130 AIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECE 187
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
+LM++Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P
Sbjct: 188 KLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRP 247
Query: 248 HLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYT 307
+LLLDEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYT
Sbjct: 248 FMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYT 307
Query: 308 GNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMV 367
GNY+ +V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+
Sbjct: 308 GNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMM 367
Query: 368 AQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLA 427
A GLTE+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+A
Sbjct: 368 ASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVA 427
Query: 428 LVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEF 487
LVGPNGAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +
Sbjct: 428 LVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCY 487
Query: 488 PEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHL 547
PE++E+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHL
Sbjct: 488 PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHL 547
Query: 548 DMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
D+ETIDALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKS
Sbjct: 548 DIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKS 607
Query: 608 KILKD 612
K++ +
Sbjct: 608 KLVDE 612
>AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein.
Length = 550
Score = 858 bits (2122), Expect = 0.0
Identities = 394/540 (72%), Positives = 457/540 (84%), Gaps = 2/540 (0%)
Query: 73 GSLAVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRR 132
G LA HP S D+ I N S+TF+G ELL DT LELN GRRYGL+GLNG GKS LL+A+G+R
Sbjct: 2 GVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKR 61
Query: 133 EVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDV 192
EVPIPEHIDI+HLTREMP SDKT L CVMEVD ER LEK AE LAH +D E+LM++
Sbjct: 62 EVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAH--EDAECEKLMEL 119
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+RL++L AD AE RA+ ILHGLGFT MQ+K KDFSGGWRMR+ALARAL+++P +LLL
Sbjct: 120 YERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLL 179
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDLDACVWLEEELK +KRILVL+SHSQDFLNGVCTNI+HM ++LKYYTGNY+
Sbjct: 180 DEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQ 239
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLT 372
+V+TR+EL ENQMK+++WEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTL KM+A GLT
Sbjct: 240 YVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLT 299
Query: 373 EKVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPN 432
E+VV DK L+FYFP CGK+PPPVIMVQNVSF+YT GP IY NLEFGIDLDTR+ALVGPN
Sbjct: 300 ERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPN 359
Query: 433 GAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE 492
GAGKSTLLKLL G+L+P+ GMIRK+SH++IGRY YMMK +PE++E
Sbjct: 360 GAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKE 419
Query: 493 REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETI 552
+EEMRKIIGRYGLTG+QQV P+R LSDGQ+CRV AWLAWQ PH+L LDEPTNHLD+ETI
Sbjct: 420 KEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETI 479
Query: 553 DALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
DALADAIN+F+GGM+LVSHDFRLI QVA EIW+CE T TKW G IL YK+HLKSK++ +
Sbjct: 480 DALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDE 539
>BC051884-1|AAH51884.2| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 429 bits (1056), Expect = e-119
Identities = 220/538 (40%), Positives = 329/538 (61%), Gaps = 10/538 (1%)
Query: 80 RSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
+S D++I NF ++F LL + L GRRYGLVG NG GK++LL L R + +P H
Sbjct: 174 KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAH 233
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYD 194
I + H+ +E+ D ALQ V+E D R L E A++ A + +L ++Y
Sbjct: 234 ISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYA 293
Query: 195 RLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDE 254
+L+++ AD A ARA+ IL GLGFT +MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDE
Sbjct: 294 KLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDE 353
Query: 255 PTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFV 314
PTN LD+ A +WLE L+ + ++++SH ++FLN + T+I+H+ +RL Y G++E F+
Sbjct: 354 PTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFI 413
Query: 315 RTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEK 374
+++ E L NQ ++Y +Q H++ +I RF + +A A Q QSK K L K+ +K
Sbjct: 414 KSKQERLLNQQREYEAQQQYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELKPVDK 472
Query: 375 VVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGA 434
+ +++ + K PP++ + V F Y D I+ L DL++R+ +VG NGA
Sbjct: 473 --ESEVVMKFPDGFEKFSPPILQLDEVDF-YYDPKHVIFSRLSVSADLESRICVVGENGA 529
Query: 435 GKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GKST+LKLL GDL P G+ + +L+IG + + ++FP R E
Sbjct: 530 GKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEE 588
Query: 495 EMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDA 554
E R +GRYG++G + P+ LS GQ+ RV FA + P+ +LDEPTNHLDMETI+A
Sbjct: 589 EYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEA 648
Query: 555 LADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
L A+N+F GG++LVSHD R I V E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 649 LGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 706
>BC051754-1|AAH51754.1| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 429 bits (1056), Expect = e-119
Identities = 220/538 (40%), Positives = 329/538 (61%), Gaps = 10/538 (1%)
Query: 80 RSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
+S D++I NF ++F LL + L GRRYGLVG NG GK++LL L R + +P H
Sbjct: 174 KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAH 233
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYD 194
I + H+ +E+ D ALQ V+E D R L E A++ A + +L ++Y
Sbjct: 234 ISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYA 293
Query: 195 RLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDE 254
+L+++ AD A ARA+ IL GLGFT +MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDE
Sbjct: 294 KLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDE 353
Query: 255 PTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFV 314
PTN LD+ A +WLE L+ + ++++SH ++FLN + T+I+H+ +RL Y G++E F+
Sbjct: 354 PTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFI 413
Query: 315 RTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEK 374
+++ E L NQ ++Y +Q H++ +I RF + +A A Q QSK K L K+ +K
Sbjct: 414 KSKQERLLNQQREYEAQQQYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELKPVDK 472
Query: 375 VVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGA 434
+ +++ + K PP++ + V F Y D I+ L DL++R+ +VG NGA
Sbjct: 473 --ESEVVMKFPDGFEKFSPPILQLDEVDF-YYDPKHVIFSRLSVSADLESRICVVGENGA 529
Query: 435 GKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GKST+LKLL GDL P G+ + +L+IG + + ++FP R E
Sbjct: 530 GKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEE 588
Query: 495 EMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDA 554
E R +GRYG++G + P+ LS GQ+ RV FA + P+ +LDEPTNHLDMETI+A
Sbjct: 589 EYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEA 648
Query: 555 LADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
L A+N+F GG++LVSHD R I V E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 649 LGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 706
>BC009253-1|AAH09253.1| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 429 bits (1056), Expect = e-119
Identities = 220/538 (40%), Positives = 329/538 (61%), Gaps = 10/538 (1%)
Query: 80 RSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
+S D++I NF ++F LL + L GRRYGLVG NG GK++LL L R + +P H
Sbjct: 174 KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAH 233
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYD 194
I + H+ +E+ D ALQ V+E D R L E A++ A + +L ++Y
Sbjct: 234 ISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYA 293
Query: 195 RLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDE 254
+L+++ AD A ARA+ IL GLGFT +MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDE
Sbjct: 294 KLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDE 353
Query: 255 PTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFV 314
PTN LD+ A +WLE L+ + ++++SH ++FLN + T+I+H+ +RL Y G++E F+
Sbjct: 354 PTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFI 413
Query: 315 RTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEK 374
+++ E L NQ ++Y +Q H++ +I RF + +A A Q QSK K L K+ +K
Sbjct: 414 KSKQERLLNQQREYEAQQQYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELKPVDK 472
Query: 375 VVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGA 434
+ +++ + K PP++ + V F Y D I+ L DL++R+ +VG NGA
Sbjct: 473 --ESEVVMKFPDGFEKFSPPILQLDEVDF-YYDPKHVIFSRLSVSADLESRICVVGENGA 529
Query: 435 GKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GKST+LKLL GDL P G+ + +L+IG + + ++FP R E
Sbjct: 530 GKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEE 588
Query: 495 EMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDA 554
E R +GRYG++G + P+ LS GQ+ RV FA + P+ +LDEPTNHLDMETI+A
Sbjct: 589 EYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEA 648
Query: 555 LADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
L A+N+F GG++LVSHD R I V E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 649 LGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 706
>AK002060-1|BAA92063.1| 709|Homo sapiens protein ( Homo sapiens
cDNA FLJ11198 fis, clone PLACE1007697, weakly similar to
GCN20 PROTEIN. ).
Length = 709
Score = 429 bits (1056), Expect = e-119
Identities = 220/538 (40%), Positives = 329/538 (61%), Gaps = 10/538 (1%)
Query: 80 RSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
+S D++I NF ++F LL + L GRRYGLVG NG GK++LL L R + +P H
Sbjct: 174 KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAH 233
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYD 194
I + H+ +E+ D ALQ V+E D R L E A++ A + +L ++Y
Sbjct: 234 ISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYA 293
Query: 195 RLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDE 254
+L+++ AD A ARA+ IL GLGFT +MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDE
Sbjct: 294 KLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDE 353
Query: 255 PTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFV 314
PTN LD+ A +WLE L+ + ++++SH ++FLN + T+I+H+ +RL Y G++E F+
Sbjct: 354 PTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFI 413
Query: 315 RTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEK 374
+++ E L NQ ++Y +Q H++ +I RF + +A A Q QSK K L K+ +K
Sbjct: 414 KSKQERLLNQQREYEAQQQYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELRPVDK 472
Query: 375 VVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGA 434
+ +++ + K PP++ + V F Y D I+ L DL++R+ +VG NGA
Sbjct: 473 --ESEVVMKFPDGFEKFSPPILQLDEVDF-YYDPKHVIFSRLSVSADLESRICVVGENGA 529
Query: 435 GKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GKST+LKLL GDL P G+ + +L+IG + + ++FP R E
Sbjct: 530 GKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEE 588
Query: 495 EMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDA 554
E R +GRYG++G + P+ LS GQ+ RV FA + P+ +LDEPTNHLDMETI+A
Sbjct: 589 EYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEA 648
Query: 555 LADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
L A+N+F GG++LVSHD R I V E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 649 LGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 706
>AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens
cDNA FLJ35096 fis, clone PLACE6006217, weakly similar to
GCN20 PROTEIN. ).
Length = 703
Score = 425 bits (1048), Expect = e-118
Identities = 219/538 (40%), Positives = 328/538 (60%), Gaps = 10/538 (1%)
Query: 80 RSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
+S D++I NF ++F LL + L GRRYGLVG NG GK++LL L R + + H
Sbjct: 168 KSYDVRIENFDVSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVSAH 227
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYD 194
I + H+ +E+ D ALQ V+E D R L E A++ A + +L ++Y
Sbjct: 228 ISLLHVEQEVAGDDTPALQSVLESDSVREDLLRRERELTAQIAAGRAEGSEAAELAEIYA 287
Query: 195 RLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDE 254
+L+++ AD A ARA+ IL GLGFT +MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDE
Sbjct: 288 KLEEIEADKAPARASVILAGLGFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDE 347
Query: 255 PTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFV 314
PTN LD+ A +WLE L+ + ++++SH ++FLN + T+I+H+ +RL Y G++E F+
Sbjct: 348 PTNMLDVRAILWLENYLQTWPSTILVVSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFI 407
Query: 315 RTRMELLENQMKQYNWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEK 374
+++ E L NQ ++Y +Q H++ +I RF + +A A Q QSK K L K+ +K
Sbjct: 408 KSKQERLLNQQREYEAQQQYRQHIQVFIDRFRY-NANRASQVQSKLKMLEKLPELKPVDK 466
Query: 375 VVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGA 434
+ +++ + K PP++ + V F Y D I+ L DL++R+ +VG NGA
Sbjct: 467 --ESEVVMKFPDGFEKFSPPILQLDEVDF-YYDPKHVIFSRLSVSADLESRICVVGENGA 523
Query: 435 GKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GKST+LKLL GDL P G+ + +L+IG + + ++FP R E
Sbjct: 524 GKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEE 582
Query: 495 EMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDA 554
E R +GRYG++G + P+ LS GQ+ RV FA + P+ +LDEPTNHLDMETI+A
Sbjct: 583 EYRHQLGRYGISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEA 642
Query: 555 LADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
L A+N+F GG++LVSHD R I V E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 643 LGRALNNFRGGVILVSHDERFIRLVCRELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 700
>BX248518-7|CAM26017.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>BX119957-3|CAM25907.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>BX000357-8|CAI18563.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>BX000357-6|CAI18562.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>BA000025-75|BAB63325.1| 807|Homo sapiens TNFalpha-inducible
ATP-binding protein protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AL662825-8|CAI17836.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AL662825-7|CAI17837.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>AL662800-8|CAI18158.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 296 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 355
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 356 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 415
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 416 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 475
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 476 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 535
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 536 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 595
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 596 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 654
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 655 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 714
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 715 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 772
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 773 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 828
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 432 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 491
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 492 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 543
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 744 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 803
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 804 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 839
>AL662800-7|CAI18159.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AF027302-1|AAC70891.1| 807|Homo sapiens TNF-alpha stimulated ABC
protein protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AB209564-1|BAD92801.1| 593|Homo sapiens ATP-binding cassette,
sub-family F, member 1 variant protein.
Length = 593
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 44 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 103
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 104 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 163
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 164 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 223
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 224 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 283
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 284 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 343
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 344 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 402
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 403 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 462
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 463 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 520
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 521 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 576
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 180 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 239
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 240 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 291
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 492 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 551
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 552 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 587
>AB202093-1|BAE78612.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AB103602-1|BAF31263.1| 807|Homo sapiens ABC50 protein protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AB088096-1|BAC54928.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 402 bits (991), Expect = e-111
Identities = 215/536 (40%), Positives = 322/536 (60%), Gaps = 12/536 (2%)
Query: 76 AVHPRSRDIKIANFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVP 135
A+ + DIK+ FSI+ +G EL + L + GRRYGLVG NG GK++LL + R +
Sbjct: 258 AMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALS 317
Query: 136 IPEHIDIFHLTREMPASDKTALQCVMEVDEERVKL-EKLAEMLAHCE--DDESQEQLMDV 192
IP +ID+ +E+ A + A+Q V+ D +R+KL E+ + E DD + E+L V
Sbjct: 318 IPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKV 377
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y+ L A AEA+A IL GLGF EMQ + T+ FSGGWRMR++LARAL+++P LL+L
Sbjct: 378 YEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLML 437
Query: 253 DEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEA 312
DEPTNHLDL+A +WL L+ +++ L+++SH Q FL+ VCT+I+H+ +RL YY GNY
Sbjct: 438 DEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMT 497
Query: 313 FVRTRMELLENQMKQYNWEQDQIAHMK--NYIARFGHGSAK--LARQAQSKEKTLAKMVA 368
F + + + +KQY ++ ++ +K + K L R+ Q + +
Sbjct: 498 FKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEES 557
Query: 369 QGLTE--KVVDDKILNFYFPSCGKVPPPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRL 426
Q E K + + F FP + PPV+ + V+F Y P ++KNL+FGID+D+R+
Sbjct: 558 QEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKP-LFKNLDFGIDMDSRI 616
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKE 486
+VGPNG GKSTLL LL G L P+ G +RKN L+IG + Y+ +
Sbjct: 617 CIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRG 676
Query: 487 FPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNH 546
F ++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+
Sbjct: 677 FN--LPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNN 734
Query: 547 LDMETIDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
LD+E+IDAL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 735 LDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 790
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/112 (29%), Positives = 55/112 (49%)
Query: 497 RKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALA 556
R+I+ G Q P ++ S G R RV A + P LL+LDEPTNHLD+ + L
Sbjct: 394 RRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLN 453
Query: 557 DAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKSK 608
+ + + +++VSHD ++ V +I + + G + +K + K
Sbjct: 454 NYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQK 505
Score = 55.6 bits (128), Expect = 5e-07
Identities = 27/96 (28%), Positives = 51/96 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLN 289
SGG + R+ A +P +L+LDEPTN+LD+++ L E + YK ++++SH +
Sbjct: 706 SGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLIT 765
Query: 290 GVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQM 325
+ + ++ + G++E + R +E L M
Sbjct: 766 ETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVM 801
>AK024758-1|BAB14989.1| 390|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21105 fis, clone CAS05114. ).
Length = 390
Score = 326 bits (801), Expect = 1e-88
Identities = 162/392 (41%), Positives = 244/392 (62%), Gaps = 5/392 (1%)
Query: 221 MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVL 280
MQQ+ T++FSGGWRMR+ALARAL+ +P LLLLDEPTN LD+ A +WLE L+ + +++
Sbjct: 1 MQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILV 60
Query: 281 ISHSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQIAHMKN 340
+SH ++FLN + T+I+H+ +RL Y G++E F++++ E L NQ ++Y +Q H++
Sbjct: 61 VSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERLLNQQREYEAQQQYRQHIQV 120
Query: 341 YIARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVVDDKILNFYFPSCGKVPPPVIMVQN 400
+I RF + +A A Q QSK K L K+ +K + +++ + K PP++ +
Sbjct: 121 FIDRFRY-NANRASQVQSKLKMLEKLPELKPVDK--ESEVVMKFPDGFEKFSPPILQLDE 177
Query: 401 VSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHL 460
V F Y D I+ L DL++R+ +VG NGAGKST+LKLL GDL P G+ + +L
Sbjct: 178 VDF-YYDPKHVIFSRLSVSADLESRICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNL 236
Query: 461 RIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDG 520
+IG + + ++FP R EE R +GRYG++G + P+ LS G
Sbjct: 237 KIGYFSQHHVEQLDLNVSAVELLARKFPG-RPEEEYRHQLGRYGISGELAMRPLASLSGG 295
Query: 521 QRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRLINQVA 580
Q+ RV FA + P+ +LDEPTNHLDMETI+AL A+N+F GG++LVSHD R I V
Sbjct: 296 QKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGRALNNFRGGVILVSHDERFIRLVC 355
Query: 581 NEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
E+W+CE G T+ EGG +Y+ L+ + ++
Sbjct: 356 RELWVCEGGGVTRVEGGFDQYRALLQEQFRRE 387
Score = 59.7 bits (138), Expect = 3e-08
Identities = 26/80 (32%), Positives = 45/80 (56%)
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
G + E+ + SGG + R+A A+ P+ +LDEPTNHLD++ L L +++
Sbjct: 279 GISGELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETIEALGRALNNFR 338
Query: 276 RILVLISHSQDFLNGVCTNI 295
++L+SH + F+ VC +
Sbjct: 339 GGVILVSHDERFIRLVCREL 358
>BX248518-8|CAM26018.1| 238|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 238
Score = 107 bits (257), Expect = 1e-22
Identities = 48/109 (44%), Positives = 75/109 (68%)
Query: 494 EEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETID 553
++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+LD+E+ID
Sbjct: 113 QDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESID 172
Query: 554 ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
AL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 173 ALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 221
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 182 DDESQEQLMDVYDRLDDLSA--DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
DD+ +E+ ++ +RL LS + A L G SGG + R+
Sbjct: 89 DDDGEEK--ELMERLKKLSRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVF 146
Query: 240 ARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMS 299
A +P +L+LDEPTN+LD+++ L E + YK ++++SH + + +
Sbjct: 147 AELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 206
Query: 300 KRRLKYYTGNYEAFVRTRMELLENQM 325
++ + G++E + R +E L M
Sbjct: 207 EQSVSQIDGDFEDYKREVLEALGEVM 232
>BX119957-4|CAM25908.1| 238|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 238
Score = 107 bits (257), Expect = 1e-22
Identities = 48/109 (44%), Positives = 75/109 (68%)
Query: 494 EEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETID 553
++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+LD+E+ID
Sbjct: 113 QDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESID 172
Query: 554 ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
AL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 173 ALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 221
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 182 DDESQEQLMDVYDRLDDLSA--DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
DD+ +E+ ++ +RL LS + A L G SGG + R+
Sbjct: 89 DDDGEEK--ELMERLKKLSRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVF 146
Query: 240 ARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMS 299
A +P +L+LDEPTN+LD+++ L E + YK ++++SH + + +
Sbjct: 147 AELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 206
Query: 300 KRRLKYYTGNYEAFVRTRMELLENQM 325
++ + G++E + R +E L M
Sbjct: 207 EQSVSQIDGDFEDYKREVLEALGEVM 232
>BX000357-7|CAM25770.1| 238|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 238
Score = 107 bits (257), Expect = 1e-22
Identities = 48/109 (44%), Positives = 75/109 (68%)
Query: 494 EEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETID 553
++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+LD+E+ID
Sbjct: 113 QDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESID 172
Query: 554 ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
AL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 173 ALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 221
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 182 DDESQEQLMDVYDRLDDLSA--DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
DD+ +E+ ++ +RL LS + A L G SGG + R+
Sbjct: 89 DDDGEEK--ELMERLKKLSRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVF 146
Query: 240 ARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMS 299
A +P +L+LDEPTN+LD+++ L E + YK ++++SH + + +
Sbjct: 147 AELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 206
Query: 300 KRRLKYYTGNYEAFVRTRMELLENQM 325
++ + G++E + R +E L M
Sbjct: 207 EQSVSQIDGDFEDYKREVLEALGEVM 232
>AL662825-6|CAM25037.1| 238|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 238
Score = 107 bits (257), Expect = 1e-22
Identities = 48/109 (44%), Positives = 75/109 (68%)
Query: 494 EEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETID 553
++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+LD+E+ID
Sbjct: 113 QDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESID 172
Query: 554 ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
AL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 173 ALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 221
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 182 DDESQEQLMDVYDRLDDLSA--DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
DD+ +E+ ++ +RL LS + A L G SGG + R+
Sbjct: 89 DDDGEEK--ELMERLKKLSRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVF 146
Query: 240 ARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMS 299
A +P +L+LDEPTN+LD+++ L E + YK ++++SH + + +
Sbjct: 147 AELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 206
Query: 300 KRRLKYYTGNYEAFVRTRMELLENQM 325
++ + G++E + R +E L M
Sbjct: 207 EQSVSQIDGDFEDYKREVLEALGEVM 232
>AL662800-6|CAI18157.2| 238|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 238
Score = 107 bits (257), Expect = 1e-22
Identities = 48/109 (44%), Positives = 75/109 (68%)
Query: 494 EEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETID 553
++ RK +GR+GL + +LS GQ+ RVVFA LA + P +L+LDEPTN+LD+E+ID
Sbjct: 113 QDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESID 172
Query: 554 ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYK 602
AL +AIN++ G +++VSHD RLI + ++W+ E + ++ +G YK
Sbjct: 173 ALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK 221
Score = 57.2 bits (132), Expect = 2e-07
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 182 DDESQEQLMDVYDRLDDLSA--DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
DD+ +E+ ++ +RL LS + A L G SGG + R+
Sbjct: 89 DDDGEEK--ELMERLKKLSRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVF 146
Query: 240 ARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMS 299
A +P +L+LDEPTN+LD+++ L E + YK ++++SH + + +
Sbjct: 147 AELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVE 206
Query: 300 KRRLKYYTGNYEAFVRTRMELLENQM 325
++ + G++E + R +E L M
Sbjct: 207 EQSVSQIDGDFEDYKREVLEALGEVM 232
>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
Length = 1280
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 1109
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 1161
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 1162 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1220
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1221 AREGRTCIVIAH 1232
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 408 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 465
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 466 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 515
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 516 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 575
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 576 ARKGRTTIVIAH 587
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1175 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1234
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1235 STI-QNADLIVVFQNG 1249
Score = 35.1 bits (77), Expect = 0.75
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 367 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALV 426
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 427 GNSGCGKSTTVQLMQRLYDPTEGMV 451
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 530 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 565
>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
Length = 1280
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 1109
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 1161
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 1162 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1220
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1221 AREGRTCIVIAH 1232
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 408 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 465
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 466 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 515
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 516 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 575
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 576 ARKGRTTIVIAH 587
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1175 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1234
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1235 STI-QNADLIVVFQNG 1249
Score = 35.1 bits (77), Expect = 0.75
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 367 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALV 426
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 427 GNSGCGKSTTVQLMQRLYDPTEGMV 451
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 530 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 565
>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 1109
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 1161
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 1162 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1220
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1221 AREGRTCIVIAH 1232
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 408 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 465
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 466 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 515
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 516 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 575
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 576 ARKGRTTIVIAH 587
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1175 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1234
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1235 STI-QNADLIVVFQNG 1249
Score = 35.5 bits (78), Expect = 0.56
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 367 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFNYPSRKEVKILKGLNLKVQSGQTVALV 426
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 427 GNSGCGKSTTVQLMQRLYDPTEGMV 451
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 530 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 565
>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 1052 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 1109
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 1110 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 1161
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 1162 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1220
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1221 AREGRTCIVIAH 1232
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 408 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 465
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 466 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 515
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 516 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 575
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 576 ARKGRTTIVIAH 587
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1175 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1234
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1235 STI-QNADLIVVFQNG 1249
Score = 35.1 bits (77), Expect = 0.75
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 367 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALV 426
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 427 GNSGCGKSTTVQLMQRLYDPTEGMV 451
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 530 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 565
>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
Length = 1279
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 1051 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 1108
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 1109 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 1160
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 1161 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1219
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1220 AREGRTCIVIAH 1231
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 407 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 464
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 465 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 514
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 515 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 574
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 575 ARKGRTTIVIAH 586
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1174 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1233
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1234 STI-QNADLIVVFQNG 1248
Score = 35.1 bits (77), Expect = 0.75
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 366 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALV 425
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 426 GNSGCGKSTTVQLMQRLYDPTEGMV 450
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 529 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 564
>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance protein
1 variant protein.
Length = 1062
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/192 (28%), Positives = 99/192 (51%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E+ + L
Sbjct: 834 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDG--KEIKRLNVQWL 891
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q +++ EA + L
Sbjct: 892 RAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------EEIVRAAKEANIHAFIESL 943
Query: 216 G--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
++ ++ K T+ SGG + RIA+ARAL +PH+LLLDE T+ LD ++ ++E L
Sbjct: 944 PNKYSTKVGDKGTQ-LSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDK 1002
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1003 AREGRTCIVIAH 1014
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P + + +++ +
Sbjct: 190 KILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDG--QDIRTINVRF 247
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + ++ + +D++ EA A + +
Sbjct: 248 LREIIGVVSQEPVLFATTIAENIRYGRENVT----------MDEIEKAVKEANAYDFIMK 297
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL--DACVWLEEEL 271
L + + + SGG + RIA+ARAL P +LLLDE T+ LD +A V + +
Sbjct: 298 LPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK 357
Query: 272 KHYKRILVLISH 283
R ++I+H
Sbjct: 358 ARKGRTTIVIAH 369
Score = 44.0 bits (99), Expect = 0.002
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + PH+LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 957 QLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1016
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1017 STI-QNADLIVVFQNG 1031
Score = 35.1 bits (77), Expect = 0.75
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 374 KVVDDKILNFYFPSCGKVPPPV---IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALV 429
K++D+K + G P + + +NV F Y I K L + +ALV
Sbjct: 149 KIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALV 208
Query: 430 GPNGAGKSTLLKLLYGDLVPSTGMI 454
G +G GKST ++L+ P+ GM+
Sbjct: 209 GNSGCGKSTTVQLMQRLYDPTEGMV 233
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 312 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 347
>AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens
cDNA FLJ31971 fis, clone NT2RP7008137, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 865
Score = 56.8 bits (131), Expect = 2e-07
Identities = 48/200 (24%), Positives = 86/200 (43%), Gaps = 17/200 (8%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G GL+G NG GKS+++ L P + + + E + D +L+C+
Sbjct: 549 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSET-SEDDGSLKCM-------- 599
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+ D + ++ ++Y + +SA + + I HGL KE QK K
Sbjct: 600 ---GYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDL-KEHLQKTVKK 655
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
G + ++ A ++ P + LLDEP+ +D A +W + K+ KR +L +H
Sbjct: 656 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHY 715
Query: 285 QDFLNGVCTNIVHMSKRRLK 304
+ VC + M +L+
Sbjct: 716 MEEAEAVCDRVAIMVSGQLR 735
Score = 49.2 bits (112), Expect = 4e-05
Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 26/222 (11%)
Query: 394 PVIMVQNVSFRYTDSGPWIY---------KNLEFGIDLDTRLALVGPNGAGKSTLLKLLY 444
P IMV N+ Y D ++ K + F + L L+GPNGAGKST++ +L
Sbjct: 511 PSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILV 570
Query: 445 GDLVPSTGMI----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GD+ P++G + + L+ Y + + +
Sbjct: 571 GDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSAS 630
Query: 495 EMRKIIGR--YGLTGRQQV-CPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
+M+++I R +GL ++ + +++L G + ++ FA P + LLDEP+ +D +
Sbjct: 631 DMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 690
Query: 552 ID----ALADAINDFDGGMVLVSHDFRLINQVANEIWICENG 589
A+ A + +L +H V + + I +G
Sbjct: 691 KQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG 732
>BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 56.4 bits (130), Expect = 3e-07
Identities = 58/190 (30%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKTA 156
+ QD L + G LVG +G GKS++L+ L R P I + H R++ +
Sbjct: 509 IFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQL--NPVWL 566
Query: 157 LQCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ V +E + +AE +A+ DD S ++ R+ A+ A A A
Sbjct: 567 RSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI-QRV----AEVANAVAFIRNFPQ 621
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
GF + +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L
Sbjct: 622 GFNTVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 680
Query: 276 --RILVLISH 283
R +++I+H
Sbjct: 681 DGRTVLVIAH 690
Score = 41.1 bits (92), Expect = 0.011
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND-FDGGMVLV-SHDFR 574
LS GQ+ R+ A + P +LLLDE T+ LD E + +A++ DG VLV +H
Sbjct: 634 LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLS 693
Query: 575 LINQVANEIWICENGTTTKW 594
I AN + + + G T++
Sbjct: 694 TIKN-ANMVAVLDQGKITEY 712
Score = 38.7 bits (86), Expect = 0.061
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 399 QNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN 457
+NV F Y I+++ I + ALVGP+G+GKST+L LL P++G I +
Sbjct: 495 KNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLD 554
Query: 458 SH 459
H
Sbjct: 555 GH 556
>AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 56.4 bits (130), Expect = 3e-07
Identities = 58/190 (30%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKTA 156
+ QD L + G LVG +G GKS++L+ L R P I + H R++ +
Sbjct: 509 IFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQL--NPVWL 566
Query: 157 LQCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ V +E + +AE +A+ DD S ++ R+ A+ A A A
Sbjct: 567 RSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI-QRV----AEVANAVAFIRNFPQ 621
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
GF + +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L
Sbjct: 622 GFNTVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 680
Query: 276 --RILVLISH 283
R +++I+H
Sbjct: 681 DGRTVLVIAH 690
Score = 41.1 bits (92), Expect = 0.011
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND-FDGGMVLV-SHDFR 574
LS GQ+ R+ A + P +LLLDE T+ LD E + +A++ DG VLV +H
Sbjct: 634 LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLS 693
Query: 575 LINQVANEIWICENGTTTKW 594
I AN + + + G T++
Sbjct: 694 TIKN-ANMVAVLDQGKITEY 712
Score = 38.7 bits (86), Expect = 0.061
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 399 QNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN 457
+NV F Y I+++ I + ALVGP+G+GKST+L LL P++G I +
Sbjct: 495 KNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLD 554
Query: 458 SH 459
H
Sbjct: 555 GH 556
>AK172794-1|BAD18770.1| 433|Homo sapiens protein ( Homo sapiens
cDNA FLJ23955 fis, clone HEP11276, highly similar to
Homo sapiens ATP-binding cassette, sub-family B
(MDR/TAP), member ).
Length = 433
Score = 56.4 bits (130), Expect = 3e-07
Identities = 58/190 (30%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKTA 156
+ QD L + G LVG +G GKS++L+ L R P I + H R++ +
Sbjct: 204 IFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQL--NPVWL 261
Query: 157 LQCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ V +E + +AE +A+ DD S ++ R+ A+ A A A
Sbjct: 262 RSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI-QRV----AEVANAVAFIRNFPQ 316
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
GF + +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L
Sbjct: 317 GFNTVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 375
Query: 276 --RILVLISH 283
R +++I+H
Sbjct: 376 DGRTVLVIAH 385
Score = 41.1 bits (92), Expect = 0.011
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND-FDGGMVLV-SHDFR 574
LS GQ+ R+ A + P +LLLDE T+ LD E + +A++ DG VLV +H
Sbjct: 329 LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLS 388
Query: 575 LINQVANEIWICENGTTTKW 594
I AN + + + G T++
Sbjct: 389 TIKN-ANMVAVLDQGKITEY 407
Score = 38.7 bits (86), Expect = 0.061
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 399 QNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN 457
+NV F Y I+++ I + ALVGP+G+GKST+L LL P++G I +
Sbjct: 190 KNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLD 249
Query: 458 SH 459
H
Sbjct: 250 GH 251
>AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein.
Length = 738
Score = 56.4 bits (130), Expect = 3e-07
Identities = 58/190 (30%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKTA 156
+ QD L + G LVG +G GKS++L+ L R P I + H R++ +
Sbjct: 509 IFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYNPASGTISLDGHDIRQL--NPVWL 566
Query: 157 LQCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ V +E + +AE +A+ DD S ++ R+ A+ A A A
Sbjct: 567 RSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI-QRV----AEVANAVAFIRNFPQ 621
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
GF + +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L
Sbjct: 622 GFNTVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 680
Query: 276 --RILVLISH 283
R +++I+H
Sbjct: 681 DGRTVLVIAH 690
Score = 41.1 bits (92), Expect = 0.011
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND-FDGGMVLV-SHDFR 574
LS GQ+ R+ A + P +LLLDE T+ LD E + +A++ DG VLV +H
Sbjct: 634 LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLS 693
Query: 575 LINQVANEIWICENGTTTKW 594
I AN + + + G T++
Sbjct: 694 TIKN-ANMVAVLDQGKITEY 712
Score = 38.7 bits (86), Expect = 0.061
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 399 QNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN 457
+NV F Y I+++ I + ALVGP+G+GKST+L LL P++G I +
Sbjct: 495 KNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYNPASGTISLD 554
Query: 458 SH 459
H
Sbjct: 555 GH 556
>AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette protein
protein.
Length = 1642
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/200 (24%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G GL+G NG GKS+++ L P I + + E + D +L+C+
Sbjct: 1326 GEILGLLGPNGAGKSTIINILVGDIEPTSGQIFLGDYSSES-SEDDDSLKCM-------- 1376
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+ D + ++ ++Y + +SA + + I H L KE QK K
Sbjct: 1377 ---GYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDL-KEHLQKTVKK 1432
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
G + ++ A ++ P + LLDEP+ +D A +W + K+ KR +L +H
Sbjct: 1433 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHY 1492
Query: 285 QDFLNGVCTNIVHMSKRRLK 304
+ VC + M +L+
Sbjct: 1493 MEEAEAVCDRVAIMVSGQLR 1512
Score = 47.6 bits (108), Expect = 1e-04
Identities = 57/244 (23%), Positives = 101/244 (41%), Gaps = 31/244 (12%)
Query: 394 PVIMVQNVSFRYTDSGPWIY---------KNLEFGIDLDTRLALVGPNGAGKSTLLKLLY 444
P IMV N+ Y D ++ K + F + L L+GPNGAGKST++ +L
Sbjct: 1288 PSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILV 1347
Query: 445 GDLVPSTGMI----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GD+ P++G I + L+ Y + + +
Sbjct: 1348 GDIEPTSGQIFLGDYSSESSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSAS 1407
Query: 495 EMRKIIGR--YGLTGRQQV-CPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
+M+++I R + L ++ + +++L G + ++ FA P + LLDEP+ +D +
Sbjct: 1408 DMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 1467
Query: 552 ID----ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
A+ A + +L +H V + + I +G + G + HLKS
Sbjct: 1468 KQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG-QLRCIGTV----QHLKS 1522
Query: 608 KILK 611
K K
Sbjct: 1523 KFGK 1526
Score = 39.1 bits (87), Expect = 0.046
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 5/131 (3%)
Query: 160 VMEVDE--ERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGF 217
V E+DE E K+ + L D + E+ + + + + A+ +L L
Sbjct: 545 VSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDM 604
Query: 218 TKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHYK 275
+ ++ K SGG + +++L A+ P +LLLDEPT +D + VW + +
Sbjct: 605 -QTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKAN 663
Query: 276 RILVLISHSQD 286
R+ V +H D
Sbjct: 664 RVTVFSTHFMD 674
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/46 (41%), Positives = 24/46 (52%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSH 459
+NL F I AL+G +G GKSTL+ +L G PS G H
Sbjct: 498 RNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGH 543
>AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5
protein.
Length = 1642
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G GL+G NG GKS+++ L P + + + E + D +L+C+
Sbjct: 1326 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSET-SEDDDSLKCM-------- 1376
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+ D + ++ ++Y + +SA + + I H L KE QK K
Sbjct: 1377 ---GYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDL-KEHLQKTVKK 1432
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
G + ++ A ++ P + LLDEP+ +D A +W + K+ KR +L +H
Sbjct: 1433 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHY 1492
Query: 285 QDFLNGVCTNIVHMSKRRLK 304
+ VC + M +L+
Sbjct: 1493 MEEAEAVCDRVAIMVSGQLR 1512
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 31/244 (12%)
Query: 394 PVIMVQNVSFRYTDSGPWIY---------KNLEFGIDLDTRLALVGPNGAGKSTLLKLLY 444
P IMV N+ Y D ++ K + F + L L+GPNGAGKST++ +L
Sbjct: 1288 PSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILV 1347
Query: 445 GDLVPSTGMI----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GD+ P++G + + L+ Y + + +
Sbjct: 1348 GDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSAS 1407
Query: 495 EMRKIIGR--YGLTGRQQV-CPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
+M+++I R + L ++ + +++L G + ++ FA P + LLDEP+ +D +
Sbjct: 1408 DMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 1467
Query: 552 ID----ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
A+ A + +L +H V + + I +G + G + HLKS
Sbjct: 1468 KQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG-QLRCIGTV----QHLKS 1522
Query: 608 KILK 611
K K
Sbjct: 1523 KFGK 1526
Score = 39.1 bits (87), Expect = 0.046
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 5/131 (3%)
Query: 160 VMEVDE--ERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGF 217
V E+DE E K+ + L D + E+ + + + + A+ +L L
Sbjct: 545 VSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDM 604
Query: 218 TKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHYK 275
+ ++ K SGG + +++L A+ P +LLLDEPT +D + VW + +
Sbjct: 605 -QTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKAN 663
Query: 276 RILVLISHSQD 286
R+ V +H D
Sbjct: 664 RVTVFSTHFMD 674
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/46 (41%), Positives = 24/46 (52%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSH 459
+NL F I AL+G +G GKSTL+ +L G PS G H
Sbjct: 498 RNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGH 543
>AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens
cDNA FLJ25441 fis, clone TST08455. ).
Length = 364
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G GL+G NG GKS+++ L P + + + E + D +L+C+
Sbjct: 48 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSET-SEDDDSLKCM-------- 98
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+ D + ++ ++Y + +SA + + I H L KE QK K
Sbjct: 99 ---GYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDL-KEHLQKTVKK 154
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
G + ++ A ++ P + LLDEP+ +D A +W + K+ KR +L +H
Sbjct: 155 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHY 214
Query: 285 QDFLNGVCTNIVHMSKRRLK 304
+ VC + M +L+
Sbjct: 215 MEEAEAVCDRVAIMVSGQLR 234
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 31/244 (12%)
Query: 394 PVIMVQNVSFRYTDSGPWIY---------KNLEFGIDLDTRLALVGPNGAGKSTLLKLLY 444
P IMV N+ Y D ++ K + F + L L+GPNGAGKST++ +L
Sbjct: 10 PSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILV 69
Query: 445 GDLVPSTGMI----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GD+ P++G + + L+ Y + + +
Sbjct: 70 GDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSAS 129
Query: 495 EMRKIIGR--YGLTGRQQV-CPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
+M+++I R + L ++ + +++L G + ++ FA P + LLDEP+ +D +
Sbjct: 130 DMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 189
Query: 552 ID----ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
A+ A + +L +H V + + I +G + G + HLKS
Sbjct: 190 KQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG-QLRCIGTV----QHLKS 244
Query: 608 KILK 611
K K
Sbjct: 245 KFGK 248
>AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein.
Length = 737
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G GL+G NG GKS+++ L P + + + E + D +L+C+
Sbjct: 421 GEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSET-SEDDDSLKCM-------- 471
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+ D + ++ ++Y + +SA + + I H L KE QK K
Sbjct: 472 ---GYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDL-KEHLQKTVKK 527
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
G + ++ A ++ P + LLDEP+ +D A +W + K+ KR +L +H
Sbjct: 528 LPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHY 587
Query: 285 QDFLNGVCTNIVHMSKRRLK 304
+ VC + M +L+
Sbjct: 588 MEEAEAVCDRVAIMVSGQLR 607
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 31/244 (12%)
Query: 394 PVIMVQNVSFRYTDSGPWIY---------KNLEFGIDLDTRLALVGPNGAGKSTLLKLLY 444
P IMV N+ Y D ++ K + F + L L+GPNGAGKST++ +L
Sbjct: 383 PSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILV 442
Query: 445 GDLVPSTGMI----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRERE 494
GD+ P++G + + L+ Y + + +
Sbjct: 443 GDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSAS 502
Query: 495 EMRKIIGR--YGLTGRQQV-CPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
+M+++I R + L ++ + +++L G + ++ FA P + LLDEP+ +D +
Sbjct: 503 DMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKA 562
Query: 552 ID----ALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGGILKYKDHLKS 607
A+ A + +L +H V + + I +G + G + HLKS
Sbjct: 563 KQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSG-QLRCIGTV----QHLKS 617
Query: 608 KILK 611
K K
Sbjct: 618 KFGK 621
>X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA)
protein.
Length = 431
Score = 54.4 bits (125), Expect = 1e-06
Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 22/198 (11%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDI---FHLTREMPASDK 154
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + F L A K
Sbjct: 196 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAK-K 254
Query: 155 TALQCVME----VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
+Q + V +E + + +AE +A+ ++ Q D++ + A
Sbjct: 255 LNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------DEIVSAAKAANIH 306
Query: 210 NILHGLGFTKEMQ--QKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWL 267
+ L E + K T+ SGG + RIA+ARAL +P +LLLDE T+ LD ++ +
Sbjct: 307 PFIETLPHKYETRVGDKGTQ-LSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVV 365
Query: 268 EEELKHYK--RILVLISH 283
+E L + R ++I+H
Sbjct: 366 QEALDKAREGRTCIVIAH 383
Score = 40.7 bits (91), Expect = 0.015
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + P +LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 326 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 385
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 386 STI-QNADLIVVFQNG 400
>EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 54.4 bits (125), Expect = 1e-06
Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 22/198 (11%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDI---FHLTREMPASDK 154
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + F L A K
Sbjct: 1051 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAK-K 1109
Query: 155 TALQCVME----VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
+Q + V +E + + +AE +A+ ++ Q D++ + A
Sbjct: 1110 LNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------DEIVSAAKAANIH 1161
Query: 210 NILHGLGFTKEMQ--QKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWL 267
+ L E + K T+ SGG + RIA+ARAL +P +LLLDE T+ LD ++ +
Sbjct: 1162 PFIETLPHKYETRVGDKGTQ-LSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVV 1220
Query: 268 EEELKHYK--RILVLISH 283
+E L + R ++I+H
Sbjct: 1221 QEALDKAREGRTCIVIAH 1238
Score = 45.2 bits (102), Expect = 7e-04
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 19/193 (9%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P I+I +++ +
Sbjct: 410 KILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDG--QDIRNFNVNY 467
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + + + +D++ EA A +
Sbjct: 468 LREIIGVVSQEPVLFSTTIAENICYGRGNVT----------MDEIKKAVKEANAYEFIMK 517
Query: 215 LG--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L F + ++ + SGG + RIA+ARAL P +LLLDE T+ LD ++ ++ L
Sbjct: 518 LPQKFDTLVGERGAQ-LSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 273 HYK--RILVLISH 283
+ R ++I+H
Sbjct: 577 KAREGRTTIVIAH 589
Score = 40.7 bits (91), Expect = 0.015
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + P +LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1181 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1240
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1241 STI-QNADLIVVFQNG 1255
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 567
>BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 54.4 bits (125), Expect = 1e-06
Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 22/198 (11%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDI---FHLTREMPASDK 154
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + F L A K
Sbjct: 1051 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAK-K 1109
Query: 155 TALQCVME----VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
+Q + V +E + + +AE +A+ ++ Q D++ + A
Sbjct: 1110 LNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------DEIVSAAKAANIH 1161
Query: 210 NILHGLGFTKEMQ--QKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWL 267
+ L E + K T+ SGG + RIA+ARAL +P +LLLDE T+ LD ++ +
Sbjct: 1162 PFIETLPHKYETRVGDKGTQ-LSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVV 1220
Query: 268 EEELKHYK--RILVLISH 283
+E L + R ++I+H
Sbjct: 1221 QEALDKAREGRTCIVIAH 1238
Score = 45.2 bits (102), Expect = 7e-04
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 19/193 (9%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P I+I +++ +
Sbjct: 410 KILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDG--QDIRNFNVNY 467
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + + + +D++ EA A +
Sbjct: 468 LREIIGVVSQEPVLFSTTIAENICYGRGNVT----------MDEIKKAVKEANAYEFIMK 517
Query: 215 LG--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L F + ++ + SGG + RIA+ARAL P +LLLDE T+ LD ++ ++ L
Sbjct: 518 LPQKFDTLVGERGAQ-LSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 273 HYK--RILVLISH 283
+ R ++I+H
Sbjct: 577 KAREGRTTIVIAH 589
Score = 40.7 bits (91), Expect = 0.015
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + P +LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1181 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1240
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1241 STI-QNADLIVVFQNG 1255
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 567
>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
glycoprotein P (mdr3) mRNA, complete cds. ).
Length = 1279
Score = 53.6 bits (123), Expect = 2e-06
Identities = 54/192 (28%), Positives = 95/192 (49%), Gaps = 17/192 (8%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ LE+ G+ LVG +GCGKS+++ L R P+ + + +E + L
Sbjct: 1051 VLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDG--QEAKKLNVQWL 1108
Query: 158 QCVME-VDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ + V +E + + +AE +A+ ++ Q D++ + A + L
Sbjct: 1109 RAQLGIVSQEPILFDCSIAENIAYGDNSRVVSQ--------DEIVSAAKAANIHPFIETL 1160
Query: 216 GFTKEMQ--QKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
E + K T+ SGG + RIA+ARAL +P +LLLDE T+ LD ++ ++E L
Sbjct: 1161 PHKYETRVGDKGTQ-LSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK 1219
Query: 274 YK--RILVLISH 283
+ R ++I+H
Sbjct: 1220 AREGRTCIVIAH 1231
Score = 45.2 bits (102), Expect = 7e-04
Identities = 49/193 (25%), Positives = 93/193 (48%), Gaps = 19/193 (9%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
++L+ L++ G+ LVG +GCGKS+ + + R P I+I +++ +
Sbjct: 410 KILKGLNLKVQSGQTVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDG--QDIRNFNVNY 467
Query: 157 LQCVMEVDEERVKL--EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L+ ++ V + L +AE + + + + +D++ EA A +
Sbjct: 468 LREIIGVVSQEPVLFSTTIAENICYGRGNVT----------MDEIKKAVKEANAYEFIMK 517
Query: 215 LG--FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L F + ++ + SGG + RIA+ARAL P +LLLDE T+ LD ++ ++ L
Sbjct: 518 LPQKFDTLVGERGAQ-LSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALD 576
Query: 273 HYK--RILVLISH 283
+ R ++I+H
Sbjct: 577 KAREGRTTIVIAH 589
Score = 40.7 bits (91), Expect = 0.015
Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A + P +LLLDE T+ LD E+ + +A++ G ++++H
Sbjct: 1174 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRL 1233
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + +NG
Sbjct: 1234 STI-QNADLIVVFQNG 1248
Score = 34.7 bits (76), Expect = 0.99
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ R+ A + P +LLLDE T+ LD E+
Sbjct: 532 QLSGGQKQRIAIARALVRNPKILLLDEATSALDTES 567
>AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding cassette
protein protein.
Length = 737
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 13/190 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKTA 156
+ QD L + G LVG +G GKS++L+ L R P I + H R++ +
Sbjct: 509 IFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQL--NPVWL 566
Query: 157 LQCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
+ V +E + +AE +A+ DD S ++ L A A N G
Sbjct: 567 RSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRGLKG----QAVAFIRNFPQG- 621
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
F + +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L
Sbjct: 622 -FNTVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 679
Query: 276 --RILVLISH 283
R +++I+H
Sbjct: 680 DGRTVLVIAH 689
Score = 50.8 bits (116), Expect = 1e-05
Identities = 61/218 (27%), Positives = 91/218 (41%), Gaps = 23/218 (10%)
Query: 399 QNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN 457
+NV F Y I+++ I + ALVGP+G+GKST+L LL P++G I +
Sbjct: 495 KNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLD 554
Query: 458 SH-----------LRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIG----- 501
H +IG Y + V E R + G
Sbjct: 555 GHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRGLKGQAVAF 614
Query: 502 -RYGLTGRQQVCPMRQ--LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
R G V + LS GQ+ R+ A + P +LLLDE T+ LD E + +A
Sbjct: 615 IRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEA 674
Query: 559 IND-FDGGMVLV-SHDFRLINQVANEIWICENGTTTKW 594
++ DG VLV +H I AN + + + G T++
Sbjct: 675 LDRLMDGRTVLVIAHRLSTIKN-ANMVAVLDQGKITEY 711
>BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 587 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 645
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 646 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 697
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 698 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 745
Score = 39.9 bits (89), Expect = 0.026
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 42 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 100
Query: 250 LLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
L+LDE T+ LD ++ ++ L+ R ++++H
Sbjct: 101 LILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 710 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 769
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 770 SAI-QNADLIVVLHNG 784
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 79 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
>BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 587 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 645
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 646 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 697
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 698 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 745
Score = 39.9 bits (89), Expect = 0.026
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 42 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 100
Query: 250 LLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
L+LDE T+ LD ++ ++ L+ R ++++H
Sbjct: 101 LILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 710 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 769
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 770 SAI-QNADLIVVLHNG 784
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 79 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
>AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5
protein.
Length = 812
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 587 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 645
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 646 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 697
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 698 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 745
Score = 39.9 bits (89), Expect = 0.026
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 42 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 100
Query: 250 LLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
L+LDE T+ LD ++ ++ L+ R ++++H
Sbjct: 101 LILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 710 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 769
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 770 SAI-QNADLIVVLHNG 784
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 79 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
>AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein.
Length = 812
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 587 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 645
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 646 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 697
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 698 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 745
Score = 39.9 bits (89), Expect = 0.026
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 42 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 100
Query: 250 LLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
L+LDE T+ LD ++ ++ L+ R ++++H
Sbjct: 101 LILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 710 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 769
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 770 SAI-QNADLIVVLHNG 784
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 79 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 136
>AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein.
Length = 832
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 607 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 665
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 666 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 717
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 718 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 765
Score = 39.9 bits (89), Expect = 0.026
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 62 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 120
Query: 250 LLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
L+LDE T+ LD ++ ++ L+ R ++++H
Sbjct: 121 LILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 156
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 730 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 789
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 790 SAI-QNADLIVVLHNG 804
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 99 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEKASKGRTTIVVAH 156
>AF319622-1|AAN76500.1| 681|Homo sapiens P-glycoprotein protein.
Length = 681
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 456 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 514
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + GL
Sbjct: 515 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGLP 566
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 567 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 614
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 579 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 638
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 639 SAI-QNADLIVVLHNG 653
>X87344-5|CAA60785.1| 748|Homo sapiens TAP1 protein.
Length = 748
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>X66401-2|CAA47025.1| 748|Homo sapiens ABC-transporter protein.
Length = 748
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>X57522-1|CAA40741.1| 808|Homo sapiens peptide transporter protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>L21208-1|AAC12906.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>L21204-1|AAC12902.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>BX088556-4|CAM26263.1| 808|Homo sapiens transporter 1 ATP-binding
cassette sub-family B (MDR/TAP) protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>BC014081-1|AAH14081.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family B (MDR/TAP) protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>AL935043-6|CAI18626.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family Bpha protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>AL671681-12|CAI17714.1| 808|Homo sapiens transporter 1,
ATP-binding cassette, sub-family Be, 9 (large
multifunctional pe protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>AL669918-8|CAI18140.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family Bpha protein.
Length = 808
Score = 52.0 bits (119), Expect = 6e-06
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 580 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 637
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 638 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 688
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 689 PQGYDTEVDE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 747
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 748 SPERYSRSVLLIT 760
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 562 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 621
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 622 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 681
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 682 HSFISGLPQGYDTEVDEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 741
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 742 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 784
>U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette protein
protein.
Length = 229
Score = 51.6 bits (118), Expect = 8e-06
Identities = 55/188 (29%), Positives = 86/188 (45%), Gaps = 10/188 (5%)
Query: 100 QDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQC 159
+D L + G LVG +G GKS++L+ L R P I +
Sbjct: 2 KDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDNPSAKPSVWLRSK 61
Query: 160 VMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFT 218
+ V +E + +AE +A+ DD S ++ R+ A+ A A A+ F
Sbjct: 62 IGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI-QRV----AEVANAVASPEFPPR-FN 115
Query: 219 KEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK--R 276
+ +K SGG + RIA+ARAL P +LLLDE T+ LD + ++E L R
Sbjct: 116 TVVGEKGVL-LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGR 174
Query: 277 ILVLISHS 284
+++I+HS
Sbjct: 175 TVLVIAHS 182
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND-FDGGMVLV-SHDFR 574
LS GQ+ R+ A + P +LLLDE T+ LD E + +A++ DG VLV +H
Sbjct: 125 LSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHSLS 184
Query: 575 LINQVANEIWICENGTTTKW 594
I AN + + + G T++
Sbjct: 185 TIKN-ANMVAVLDQGKITEY 203
Score = 38.3 bits (85), Expect = 0.080
Identities = 19/47 (40%), Positives = 28/47 (59%)
Query: 413 YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSH 459
+K+ I + ALVGP+G+GKST+L LL P++G I + H
Sbjct: 1 FKDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGH 47
>AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant
protein.
Length = 776
Score = 51.6 bits (118), Expect = 8e-06
Identities = 59/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 346 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 402
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
KE+ + R + ++ + L G V R LS GQ+ RV
Sbjct: 403 SGTLRSNILFGKEYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 462
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 463 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 521
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 522 ILKDGKMVQ-KG---TYTEFLKSGI 542
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 453 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 511
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 512 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 557
>L21206-1|AAC12904.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 51.2 bits (117), Expect = 1e-05
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVGE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>L21205-1|AAC12903.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 51.2 bits (117), Expect = 1e-05
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVGE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>AY523971-1|AAS55412.1| 748|Homo sapiens TAP1 protein.
Length = 748
Score = 51.2 bits (117), Expect = 1e-05
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVGE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>AY523970-1|AAS55411.1| 748|Homo sapiens TAP1 protein.
Length = 748
Score = 51.2 bits (117), Expect = 1e-05
Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG R +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVGE-AGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDILVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQR V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 50.4 bits (115), Expect = 2e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 2066 GRILAVDRLCLGVRLGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 2109
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 2110 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 2168
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 2169 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 2227
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 2228 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 2265
Score = 36.7 bits (81), Expect = 0.24
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 18/213 (8%)
Query: 393 PPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
P V+ V ++ Y D L + + ++ +G NGAGK+T + +L G P++G
Sbjct: 988 PLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSG 1047
Query: 453 M--------------IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRK 498
IRKN + ++ +K + R EM K
Sbjct: 1048 SATIYGHDIRTEMDEIRKNLGM-CPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK 1106
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
+I L+ ++ ++ LS G + ++ A ++LDEPT +D A+ D
Sbjct: 1107 MIEDLELSNKRHSL-VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDL 1165
Query: 559 INDFDGG--MVLVSHDFRLINQVANEIWICENG 589
I + G ++L +H + + + I I +G
Sbjct: 1166 ILKYKPGRTILLSTHHMDEADLLGDRIAIISHG 1198
Score = 33.9 bits (74), Expect = 1.7
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 187 EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVK 246
E+ + Y RL ++ + ++ L + + + + SGG + ++++A A
Sbjct: 1083 EEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNK-RHSLVQTLSGGMKRKLSVAIAFVGG 1141
Query: 247 PHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
++LDEPT +D A + + + YK R ++L +H D + + I +S +LK
Sbjct: 1142 SRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLK 1201
Score = 31.9 bits (69), Expect = 7.0
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 419 GIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSH 459
G+ L L+G NGAGK++ K+L GD + G N H
Sbjct: 2077 GVRLGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGH 2117
>BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein.
Length = 859
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
>AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette
transporter C4 protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug
resistance-associated protein protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette
protein C4 splice variant A protein.
Length = 1278
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 982 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1041
Query: 444 Y 444
+
Sbjct: 1042 F 1042
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 38.3 bits (85), Expect = 0.080
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1000 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1058
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V ++ + E+L + + +T E
Sbjct: 1059 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQ--LKETIED 1114
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1115 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1167
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1168 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1212
>AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B
isoform protein.
Length = 893
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 19 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 75
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 76 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 135
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 136 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 194
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 195 ILKDGKMVQ-KG---TYTEFLKSGI 215
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 619 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 678
Query: 444 Y 444
+
Sbjct: 679 F 679
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 126 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 184
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 185 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 230
Score = 37.5 bits (83), Expect = 0.14
Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 637 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 695
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V + + E+L + + +T E
Sbjct: 696 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFKEHTDEELWNALQEVQ--LKETIED 751
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 752 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 804
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 805 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 849
>AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B
protein.
Length = 1325
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/205 (28%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRIGRYXXXXXXXX 473
+ L F + LA+VGP GAGKS+LL + G+L PS G++ + H RI Y
Sbjct: 429 QGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLV--SVHGRIA-YVSQQPWVF 485
Query: 474 XXXXXXXXYMMKEFPEVREREEMRKIIGRYGL----TGRQQVCPMR--QLSDGQRCRVVF 527
K++ + R + ++ + L G V R LS GQ+ RV
Sbjct: 486 SGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNL 545
Query: 528 AWLAWQTPHLLLLDEPTNHLDMETIDALAD-AINDF--DGGMVLVSHDFRLINQVANEIW 584
A +Q + LLD+P + +D E L + I + +LV+H + + + A++I
Sbjct: 546 ARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYL-KAASQIL 604
Query: 585 ICENGTTTKWEGGILKYKDHLKSKI 609
I ++G + +G Y + LKS I
Sbjct: 605 ILKDGKMVQ-KG---TYTEFLKSGI 625
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 6/61 (9%)
Query: 390 KVPPP------VIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
K PPP VI+ NV+F Y+ GP + K+L I ++ +VG GAGKS+L+ L
Sbjct: 1029 KRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISAL 1088
Query: 444 Y 444
+
Sbjct: 1089 F 1089
Score = 41.9 bits (94), Expect = 0.007
Identities = 28/109 (25%), Positives = 58/109 (53%), Gaps = 8/109 (7%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE----ELKHYKRILVLISHSQ 285
SGG + R+ LARA+Y + LLD+P + +D + L E ++ H ++I +L++H
Sbjct: 536 SGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILH-EKITILVTHQL 594
Query: 286 DFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
+L ++ + ++ G Y F+++ ++ + +K+ N E +Q
Sbjct: 595 QYLKAASQILILKDGKMVQ--KGTYTEFLKSGID-FGSLLKKDNEESEQ 640
Score = 37.5 bits (83), Expect = 0.14
Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 16/226 (7%)
Query: 88 NFSITFYGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPE-HIDIFHLT 146
NF + G +L+ + + G+VG G GKSSL++AL R P + ID LT
Sbjct: 1047 NFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKI-LT 1105
Query: 147 REMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEA 206
E+ D + + +E V + + E+L + + +T E
Sbjct: 1106 TEIGLHDLRKKMSI--IPQEPVLFTGTMRKNLDPFKEHTDEELWNALQEVQ--LKETIED 1161
Query: 207 RAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVW 266
+ E+ + + +FS G R + LARA+ K +L++DE T ++D
Sbjct: 1162 LPGKM------DTELAESGS-NFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDEL 1214
Query: 267 LEEELKH-YKRILVL-ISHSQDFLNGVCTNIVHMSKRRLKYYTGNY 310
++++++ + VL I+H + + I+ + RLK Y Y
Sbjct: 1215 IQKKIREKFAHCTVLTIAHRLNTIID-SDKIMVLDSGRLKEYDEPY 1259
>L21207-1|AAC12905.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 49.6 bits (113), Expect = 3e-05
Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 20/193 (10%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+LQ L G LVG NG GKS++ A L P + + + +P + L
Sbjct: 520 VLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDG--KPLPQYEHRYL 577
Query: 158 --QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL 215
Q E +V L E +A+ +Q+ M+ +++A ++ A + + GL
Sbjct: 578 HRQVAAVGQEPQVFGRSLQENIAY---GLTQKPTME------EITAAAVKSGAHSFISGL 628
Query: 216 --GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL-- 271
G+ E+ + A SGG + +ALARAL KP +L+LD+ T+ LD ++ + +E+ L
Sbjct: 629 PQGYDTEVGE-AGSQLSGGQQQAVALARALIRKPCVLILDDATSALDANSQLQVEQLLYE 687
Query: 272 --KHYKRILVLIS 282
+ Y R ++LI+
Sbjct: 688 SPERYSRSVLLIT 700
Score = 41.5 bits (93), Expect = 0.009
Identities = 54/226 (23%), Positives = 91/226 (40%), Gaps = 26/226 (11%)
Query: 395 VIMVQNVSFRYTDSGP-WIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
++ Q+VSF Y + + + L F + ALVGPNG+GKST+ LL P+ G
Sbjct: 502 LVQFQDVSFAYPNRPDVLVLQGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQ 561
Query: 454 I-----------RKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
+ + H ++ Y + + P + E G
Sbjct: 562 LLLDGKPLPQYEHRYLHRQVAAVGQEPQVFGRSLQENIAYGLTQKPTMEEITAAAVKSGA 621
Query: 503 YG-LTGRQQVCPMR------QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD----MET 551
+ ++G Q QLS GQ+ V A + P +L+LD+ T+ LD ++
Sbjct: 622 HSFISGLPQGYDTEVGEAGSQLSGGQQQAVALARALIRKPCVLILDDATSALDANSQLQV 681
Query: 552 IDALADAINDFDGGMVLVSHDFRLINQVANEIWICENGTTTKWEGG 597
L ++ + ++L++ L+ Q A+ I E G EGG
Sbjct: 682 EQLLYESPERYSRSVLLITQHLSLVEQ-ADHILFLEGGAIR--EGG 724
>BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/227 (27%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 469 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 526
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 527 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 578
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 579 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 637
Query: 272 KHYK--RILVLISHSQDFLNGV-CTNIVHMSKRRLKYYTGNYEAFVR 315
R +++I+H + G C IV M+ R+ + G +E ++
Sbjct: 638 DRASAGRTVLVIAHRLSTVRGAHC--IVVMADGRV-WEAGTHEELLK 681
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDFR 574
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++++H
Sbjct: 595 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 654
Query: 575 LINQVANEIWICENGTTTKWEGG 597
+ + A+ I + +G WE G
Sbjct: 655 TV-RGAHCIVVMADGRV--WEAG 674
>BC008755-1|AAH08755.1| 867|Homo sapiens ABCA2 protein protein.
Length = 867
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 497 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 540
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 541 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 599
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 600 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 658
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 659 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 696
>AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein.
Length = 812
Score = 49.6 bits (113), Expect = 3e-05
Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 13/169 (7%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L + G+ VG +GCGKS+ + L R P+ + +F + +
Sbjct: 587 ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQV-LFDGVDAKELNVQWLR 645
Query: 158 QCVMEVDEERVKLE-KLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
+ V +E V +AE +A+ ++ LD++ A + + G
Sbjct: 646 SQIAIVPQEPVLFNCSIAENIAYGDNSRVVP--------LDEIKEAANAANIHSFIEGPP 697
Query: 217 --FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA 263
+ ++ K + SGG + R+A+ARAL KP +LLLDE T+ LD D+
Sbjct: 698 EKYNTQVGLKGAQ-LSGGQKQRLAIARALLQKPKILLLDEATSALDNDS 745
Score = 39.5 bits (88), Expect = 0.035
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 197 DDLSADTAEARAANILHGLGFTKEMQQKATK-------DFSGGWRMRIALARALYVKPHL 249
DD++ + E RAA + F E K SGG + RIA+ARAL P +
Sbjct: 42 DDVTDEEME-RAAREANAYDFIMEFPNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKI 100
Query: 250 LLLDEPTNHLDLDA 263
L+LDE T+ LD ++
Sbjct: 101 LILDEATSALDSES 114
Score = 37.9 bits (84), Expect = 0.11
Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS GQ+ R+ A Q P +LLLDE T+ LD ++ + A++ G ++V+H
Sbjct: 710 QLSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDKARTGRTCLVVTHRL 769
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + NG
Sbjct: 770 SAI-QNADLIVVLHNG 784
Score = 36.7 bits (81), Expect = 0.24
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSH 571
Q+S GQ+ R+ A + P +L+LDE T+ LD E+ A+ A+ G ++V+H
Sbjct: 79 QMSGGQKQRIAIARALVRNPKILILDEATSALDSESESAVQAALEKASKGRTTIVVAH 136
>AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 2435
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 2065 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 2108
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 2109 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 2167
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 2168 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 2226
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 2227 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 2264
Score = 36.7 bits (81), Expect = 0.24
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 18/213 (8%)
Query: 393 PPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
P V+ V ++ Y D L + + ++ +G NGAGK+T + +L G P++G
Sbjct: 987 PLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSG 1046
Query: 453 M--------------IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRK 498
IRKN + ++ +K + R EM K
Sbjct: 1047 SATIYGHDIRTEMDEIRKNLGM-CPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK 1105
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
+I L+ ++ ++ LS G + ++ A ++LDEPT +D A+ D
Sbjct: 1106 MIEDLELSNKRHSL-VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDL 1164
Query: 559 INDFDGG--MVLVSHDFRLINQVANEIWICENG 589
I + G ++L +H + + + I I +G
Sbjct: 1165 ILKYKPGRTILLSTHHMDEADLLGDRIAIISHG 1197
Score = 33.9 bits (74), Expect = 1.7
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 187 EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVK 246
E+ + Y RL ++ + ++ L + + + + SGG + ++++A A
Sbjct: 1082 EEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNK-RHSLVQTLSGGMKRKLSVAIAFVGG 1140
Query: 247 PHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
++LDEPT +D A + + + YK R ++L +H D + + I +S +LK
Sbjct: 1141 SRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLK 1200
>AL807752-20|CAI12766.1| 226|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 226
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 19 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 62
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 63 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 121
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 122 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 180
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 181 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 218
>AL162060-1|CAB82398.1| 373|Homo sapiens hypothetical protein
protein.
Length = 373
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 3 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 46
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 47 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 105
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 106 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 164
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 165 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 202
>AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette,
sub-family B, member 8 variant protein.
Length = 718
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/227 (27%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 469 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 526
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 527 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 578
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 579 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 637
Query: 272 KHYK--RILVLISHSQDFLNGV-CTNIVHMSKRRLKYYTGNYEAFVR 315
R +++I+H + G C IV M+ R+ + G +E ++
Sbjct: 638 DRASAGRTVLVIAHRLSTVRGAHC--IVVMADGRV-WEAGTHEELLK 681
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDFR 574
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++++H
Sbjct: 595 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 654
Query: 575 LINQVANEIWICENGTTTKWEGG 597
+ + A+ I + +G WE G
Sbjct: 655 TV-RGAHCIVVMADGRV--WEAG 674
>AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens
cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to
Homo sapiens ATP-binding cassette protein M-ABC1 mRNA.
).
Length = 701
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/227 (27%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 452 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 509
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 510 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 561
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 562 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 620
Query: 272 KHYK--RILVLISHSQDFLNGV-CTNIVHMSKRRLKYYTGNYEAFVR 315
R +++I+H + G C IV M+ R+ + G +E ++
Sbjct: 621 DRASAGRTVLVIAHRLSTVRGAHC--IVVMADGRV-WEAGTHEELLK 664
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDFR 574
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++++H
Sbjct: 578 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 637
Query: 575 LINQVANEIWICENGTTTKWEGG 597
+ + A+ I + +G WE G
Sbjct: 638 TV-RGAHCIVVMADGRV--WEAG 657
>AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens
cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to
ATP-DEPENDENT PERMEASE MDL1. ).
Length = 735
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/227 (27%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 486 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 543
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 544 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 595
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 596 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 654
Query: 272 KHYK--RILVLISHSQDFLNGV-CTNIVHMSKRRLKYYTGNYEAFVR 315
R +++I+H + G C IV M+ R+ + G +E ++
Sbjct: 655 DRASAGRTVLVIAHRLSTVRGAHC--IVVMADGRV-WEAGTHEELLK 698
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDFR 574
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++++H
Sbjct: 612 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 671
Query: 575 LINQVANEIWICENGTTTKWEGG 597
+ + A+ I + +G WE G
Sbjct: 672 TV-RGAHCIVVMADGRV--WEAG 691
>AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 2066 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 2109
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 2110 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 2168
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 2169 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 2227
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 2228 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 2265
Score = 36.7 bits (81), Expect = 0.24
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 18/213 (8%)
Query: 393 PPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
P V+ V ++ Y D L + + ++ +G NGAGK+T + +L G P++G
Sbjct: 988 PLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSG 1047
Query: 453 M--------------IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRK 498
IRKN + ++ +K + R EM K
Sbjct: 1048 SATIYGHDIRTEMDEIRKNLGM-CPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK 1106
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
+I L+ ++ ++ LS G + ++ A ++LDEPT +D A+ D
Sbjct: 1107 MIEDLELSNKRHSL-VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDL 1165
Query: 559 INDFDGG--MVLVSHDFRLINQVANEIWICENG 589
I + G ++L +H + + + I I +G
Sbjct: 1166 ILKYKPGRTILLSTHHMDEADLLGDRIAIISHG 1198
Score = 33.9 bits (74), Expect = 1.7
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 187 EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVK 246
E+ + Y RL ++ + ++ L + + + + SGG + ++++A A
Sbjct: 1083 EEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNK-RHSLVQTLSGGMKRKLSVAIAFVGG 1141
Query: 247 PHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
++LDEPT +D A + + + YK R ++L +H D + + I +S +LK
Sbjct: 1142 SRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLK 1201
>AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette
sub-family A member 2 protein.
Length = 2436
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 2066 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 2109
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 2110 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 2168
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 2169 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 2227
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 2228 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 2265
Score = 36.7 bits (81), Expect = 0.24
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 18/213 (8%)
Query: 393 PPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
P V+ V ++ Y D L + + ++ +G NGAGK+T + +L G P++G
Sbjct: 988 PLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSG 1047
Query: 453 M--------------IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRK 498
IRKN + ++ +K + R EM K
Sbjct: 1048 SATIYGHDIRTEMDEIRKNLGM-CPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK 1106
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
+I L+ ++ ++ LS G + ++ A ++LDEPT +D A+ D
Sbjct: 1107 MIEDLELSNKRHSL-VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDL 1165
Query: 559 INDFDGG--MVLVSHDFRLINQVANEIWICENG 589
I + G ++L +H + + + I I +G
Sbjct: 1166 ILKYKPGRTILLSTHHMDEADLLGDRIAIISHG 1198
Score = 33.9 bits (74), Expect = 1.7
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 187 EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVK 246
E+ + Y RL ++ + ++ L + + + + SGG + ++++A A
Sbjct: 1083 EEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNK-RHSLVQTLSGGMKRKLSVAIAFVGG 1141
Query: 247 PHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
++LDEPT +D A + + + YK R ++L +H D + + I +S +LK
Sbjct: 1142 SRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLK 1201
>AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette
protein M-ABC1 protein.
Length = 718
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/227 (27%), Positives = 110/227 (48%), Gaps = 20/227 (8%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 469 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 526
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 527 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 578
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 579 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 637
Query: 272 KHYK--RILVLISHSQDFLNGV-CTNIVHMSKRRLKYYTGNYEAFVR 315
R +++I+H + G C IV M+ R+ + G +E ++
Sbjct: 638 DRASAGRTVLVIAHRLSTVRGAHC--IVVMADGRV-WEAGTHEELLK 681
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDFR 574
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++++H
Sbjct: 595 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLS 654
Query: 575 LINQVANEIWICENGTTTKWEGG 597
+ + A+ I + +G WE G
Sbjct: 655 TV-RGAHCIVVMADGRV--WEAG 674
>AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.
Length = 1771
Score = 49.6 bits (113), Expect = 3e-05
Identities = 61/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 95 GSELLQDTL-LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASD 153
G L D L L + G +GL+G+NG GK+S L T + +
Sbjct: 1401 GRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKML----------------TGDESTTG 1444
Query: 154 KTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSADTAEARAAN 210
A V +E +++++ C+ D+ + + + +Y RL +S EAR
Sbjct: 1445 GEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKD-EARVVK 1503
Query: 211 -ILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW- 266
L L TK K +SGG + +++ A AL P + LDEPT +D A +W
Sbjct: 1504 WALEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWN 1562
Query: 267 LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
L +L R +VL SHS + +CT + M RL+
Sbjct: 1563 LILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLR 1600
Score = 36.7 bits (81), Expect = 0.24
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 18/213 (8%)
Query: 393 PPVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
P V+ V ++ Y D L + + ++ +G NGAGK+T + +L G P++G
Sbjct: 323 PLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSG 382
Query: 453 M--------------IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRK 498
IRKN + ++ +K + R EM K
Sbjct: 383 SATIYGHDIRTEMDEIRKNLGM-CPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDK 441
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA 558
+I L+ ++ ++ LS G + ++ A ++LDEPT +D A+ D
Sbjct: 442 MIEDLELSNKRHSL-VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDL 500
Query: 559 INDFDGG--MVLVSHDFRLINQVANEIWICENG 589
I + G ++L +H + + + I I +G
Sbjct: 501 ILKYKPGRTILLSTHHMDEADLLGDRIAIISHG 533
Score = 33.9 bits (74), Expect = 1.7
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 187 EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVK 246
E+ + Y RL ++ + ++ L + + + + SGG + ++++A A
Sbjct: 418 EEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNK-RHSLVQTLSGGMKRKLSVAIAFVGG 476
Query: 247 PHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
++LDEPT +D A + + + YK R ++L +H D + + I +S +LK
Sbjct: 477 SRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLK 536
>Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.
Length = 2273
Score = 48.8 bits (111), Expect = 6e-05
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEER- 167
G +GL+G+NG GK++ L D + + + K+ L + EV +
Sbjct: 1965 GECFGLLGVNGAGKTTTFKMLTG---------DTTVTSGDATVAGKSILTNISEVHQNMG 2015
Query: 168 --VKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKA 225
+ + + E+L +E L +Y RL + A+ E A + LG T A
Sbjct: 2016 YCPQFDAIDELLT------GREHLY-LYARLRGVPAEEIEKVANWSIKSLGLTVYADCLA 2068
Query: 226 TKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLIS 282
+SGG + +++ A AL P L+LLDEPT +D A +W + + R +VL S
Sbjct: 2069 GT-YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTS 2127
Query: 283 HSQDFLNGVCTNIVHMSK 300
HS + +CT + M K
Sbjct: 2128 HSMEECEALCTRLAIMVK 2145
Score = 37.1 bits (82), Expect = 0.19
Identities = 29/118 (24%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y +L S + A+ +L G + ++A +D SGG + ++++A A +++L
Sbjct: 1027 YAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEA-QDLSGGMQRKLSVAIAFVGDAKVVIL 1085
Query: 253 DEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLKYYTG 308
DEPT+ +D + + + L Y+ R +++ +H D + + I +++ RL Y +G
Sbjct: 1086 DEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIIAQGRL-YCSG 1142
Score = 32.3 bits (70), Expect = 5.3
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
A +G NGAGK+T L +L G L P++G +
Sbjct: 960 AFLGHNGAGKTTTLSILTGLLPPTSGTV 987
>U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 48.8 bits (111), Expect = 6e-05
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEER- 167
G +GL+G+NG GK++ L D + + + K+ L + EV +
Sbjct: 1965 GECFGLLGVNGAGKTTTFKMLTG---------DTTVTSGDATVAGKSILTNISEVHQNMG 2015
Query: 168 --VKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKA 225
+ + + E+L +E L +Y RL + A+ E A + LG T A
Sbjct: 2016 YCPQFDAIDELLT------GREHLY-LYARLRGVPAEEIEKVANWSIKSLGLTVYADCLA 2068
Query: 226 TKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLIS 282
+SGG + +++ A AL P L+LLDEPT +D A +W + + R +VL S
Sbjct: 2069 GT-YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIRKGRAVVLTS 2127
Query: 283 HSQDFLNGVCTNIVHMSK 300
HS + +CT + M K
Sbjct: 2128 HSMEECEALCTRLAIMVK 2145
Score = 36.3 bits (80), Expect = 0.32
Identities = 29/118 (24%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y +L S + A+ +L G + ++A +D SGG + ++++A A +++L
Sbjct: 1027 YAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEA-QDLSGGMQRKLSVAIAFVGDAKVVIL 1085
Query: 253 DEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLKYYTG 308
DEPT+ +D + + + L Y+ R +++ +H D + I +++ RL Y +G
Sbjct: 1086 DEPTSGVDPYSRRSIWDLLLKYRSGRTIIMPTHHMDEADHQGDRIAIIAQGRL-YCSG 1142
Score = 32.3 bits (70), Expect = 5.3
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
A +G NGAGK+T L +L G L P++G +
Sbjct: 960 AFLGHNGAGKTTTLSILTGLLPPTSGTV 987
>AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter protein.
Length = 2273
Score = 48.8 bits (111), Expect = 6e-05
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEER- 167
G +GL+G+NG GK++ L D + + + K+ L + EV +
Sbjct: 1965 GECFGLLGVNGAGKTTTFKMLTG---------DTTVTSGDATVAGKSILTNISEVHQNMG 2015
Query: 168 --VKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKA 225
+ + + E+L +E L +Y RL + A+ E A + LG T A
Sbjct: 2016 YCPQFDAIDELLT------GREHLY-LYARLRGVPAEEIEKVANWSIKSLGLTVYADCLA 2068
Query: 226 TKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLIS 282
+SGG + +++ A AL P L+LLDEPT +D A +W + + R +VL S
Sbjct: 2069 GT-YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTS 2127
Query: 283 HSQDFLNGVCTNIVHMSK 300
HS + +CT + M K
Sbjct: 2128 HSMEECEALCTRLAIMVK 2145
Score = 37.1 bits (82), Expect = 0.19
Identities = 29/118 (24%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y +L S + A+ +L G + ++A +D SGG + ++++A A +++L
Sbjct: 1027 YAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEA-QDLSGGMQRKLSVAIAFVGDAKVVIL 1085
Query: 253 DEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLKYYTG 308
DEPT+ +D + + + L Y+ R +++ +H D + + I +++ RL Y +G
Sbjct: 1086 DEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIIAQGRL-YCSG 1142
Score = 32.3 bits (70), Expect = 5.3
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
A +G NGAGK+T L +L G L P++G +
Sbjct: 960 AFLGHNGAGKTTTLSILTGLLPPTSGTV 987
>AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein
protein.
Length = 2303
Score = 48.8 bits (111), Expect = 6e-05
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEER- 167
G +GL+G+NG GK++ L D + + + K+ L + EV +
Sbjct: 1995 GECFGLLGVNGAGKTTTFKMLTG---------DTTVTSGDATVAGKSILTNISEVHQNMG 2045
Query: 168 --VKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKA 225
+ + + E+L +E L +Y RL + A+ E A + LG T A
Sbjct: 2046 YCPQFDAIDELLT------GREHLY-LYARLRGVPAEEIEKVANWSIKSLGLTVYADCLA 2098
Query: 226 TKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLIS 282
+SGG + +++ A AL P L+LLDEPT +D A +W + + R +VL S
Sbjct: 2099 GT-YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTS 2157
Query: 283 HSQDFLNGVCTNIVHMSK 300
HS + +CT + M K
Sbjct: 2158 HSMEECEALCTRLAIMVK 2175
Score = 37.1 bits (82), Expect = 0.19
Identities = 29/118 (24%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y +L S + A+ +L G + ++A +D SGG + ++++A A +++L
Sbjct: 1057 YAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEA-QDLSGGMQRKLSVAIAFVGDAKVVIL 1115
Query: 253 DEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLKYYTG 308
DEPT+ +D + + + L Y+ R +++ +H D + + I +++ RL Y +G
Sbjct: 1116 DEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIIAQGRL-YCSG 1172
Score = 32.3 bits (70), Expect = 5.3
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
A +G NGAGK+T L +L G L P++G +
Sbjct: 990 AFLGHNGAGKTTTLSILTGLLPPTSGTV 1017
>AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subfamily
A protein.
Length = 2595
Score = 48.4 bits (110), Expect = 7e-05
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 18/194 (9%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G +GL+G+NG GK+++ L +P +I I + T + D + E+ +
Sbjct: 2283 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAL 2342
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+D + E+ + Y R+ + + +L L + +AT
Sbjct: 2343 ------------DDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP-FKDRATSM 2389
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
S G + +++ A AL KP +LLLDEP++ +D + +W + EE+++ K ++L SHS
Sbjct: 2390 CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQN-KCSVILTSHS 2448
Query: 285 QDFLNGVCTNIVHM 298
+ +CT + M
Sbjct: 2449 MEECEALCTRLAIM 2462
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 18/192 (9%)
Query: 415 NLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--MIRK--------NSHLR-IG 463
N+ GI L+G NGAGK+T+ K+L GD++PS+G +IR +SH +G
Sbjct: 2275 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVG 2334
Query: 464 RYXXXXXXXXXXXXXXXXYM---MKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDG 520
Y + PE +E + K++ R L + S G
Sbjct: 2335 YCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRA-TSMCSYG 2393
Query: 521 QRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND---FDGGMVLVSHDFRLIN 577
+ ++ A P +LLLDEP++ +D ++ L I++ ++L SH
Sbjct: 2394 TKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECE 2453
Query: 578 QVANEIWICENG 589
+ + I NG
Sbjct: 2454 ALCTRLAIMVNG 2465
Score = 31.5 bits (68), Expect = 9.2
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+L+GPNGAGK+T + +L G S G I
Sbjct: 1375 SLLGPNGAGKTTTISMLTGLFGASAGTI 1402
>AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2277
Score = 48.4 bits (110), Expect = 7e-05
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 18/194 (9%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G +GL+G+NG GK+++ L +P +I I + T + D + E+ +
Sbjct: 1965 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAL 2024
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+D + E+ + Y R+ + + +L L + +AT
Sbjct: 2025 ------------DDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP-FKDRATSM 2071
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
S G + +++ A AL KP +LLLDEP++ +D + +W + EE+++ K ++L SHS
Sbjct: 2072 CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQN-KCSVILTSHS 2130
Query: 285 QDFLNGVCTNIVHM 298
+ +CT + M
Sbjct: 2131 MEECEALCTRLAIM 2144
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 18/192 (9%)
Query: 415 NLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--MIRK--------NSHLR-IG 463
N+ GI L+G NGAGK+T+ K+L GD++PS+G +IR +SH +G
Sbjct: 1957 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVG 2016
Query: 464 RYXXXXXXXXXXXXXXXXYM---MKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDG 520
Y + PE +E + K++ R L + S G
Sbjct: 2017 YCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRA-TSMCSYG 2075
Query: 521 QRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND---FDGGMVLVSHDFRLIN 577
+ ++ A P +LLLDEP++ +D ++ L I++ ++L SH
Sbjct: 2076 TKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECE 2135
Query: 578 QVANEIWICENG 589
+ + I NG
Sbjct: 2136 ALCTRLAIMVNG 2147
Score = 31.5 bits (68), Expect = 9.2
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+L+GPNGAGK+T + +L G S G I
Sbjct: 1057 SLLGPNGAGKTTTISMLTGLFGASAGTI 1084
>AL359813-2|CAI23217.1| 1492|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 10 protein.
Length = 1492
Score = 48.4 bits (110), Expect = 7e-05
Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 24/161 (14%)
Query: 104 LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEV 163
LE+ G G+VG GCGKSSLLAA+ + H+ + L++ +
Sbjct: 621 LEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFG----------LAT 670
Query: 164 DEERVKLEKLAEMLAHCEDDESQ--EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEM 221
E ++ + + + + ++Q +++++ DDLS A G E+
Sbjct: 671 QEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPA-----------GDQTEV 719
Query: 222 QQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLD 262
+K SGG R RIALARA+Y + L LLD+P +D D
Sbjct: 720 GEKGVT-LSGGQRARIALARAVYQEKELYLLDDPLAAVDAD 759
Score = 35.5 bits (78), Expect = 0.56
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 399 QNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
Q+V Y P + F + +L +VG G+GKS+LL +L+ L PS+G +
Sbjct: 1249 QDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRV 1304
>AK000002-1|BAA92227.1| 1513|Homo sapiens FLJ00002 protein protein.
Length = 1513
Score = 48.4 bits (110), Expect = 7e-05
Identities = 47/161 (29%), Positives = 75/161 (46%), Gaps = 24/161 (14%)
Query: 104 LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEV 163
LE+ G G+VG GCGKSSLLAA+ + H+ + L++ +
Sbjct: 642 LEVKKGMLVGIVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFG----------LAT 691
Query: 164 DEERVKLEKLAEMLAHCEDDESQ--EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEM 221
E ++ + + + + ++Q +++++ DDLS A G E+
Sbjct: 692 QEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPA-----------GDQTEV 740
Query: 222 QQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLD 262
+K SGG R RIALARA+Y + L LLD+P +D D
Sbjct: 741 GEKGVT-LSGGQRARIALARAVYQEKELYLLDDPLAAVDAD 780
Score = 35.5 bits (78), Expect = 0.56
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 399 QNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
Q+V Y P + F + +L +VG G+GKS+LL +L+ L PS+G +
Sbjct: 1270 QDVVLAYRPGLPNALDGVTFCVQPGEKLGIVGRTGSGKSSLLLVLFRLLEPSSGRV 1325
>AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2347
Score = 48.4 bits (110), Expect = 7e-05
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 18/194 (9%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEERV 168
G +GL+G+NG GK+++ L +P +I I + T + D + E+ +
Sbjct: 2035 GECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDAL 2094
Query: 169 KLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKD 228
+D + E+ + Y R+ + + +L L + +AT
Sbjct: 2095 ------------DDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMP-FKDRATSM 2141
Query: 229 FSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHS 284
S G + +++ A AL KP +LLLDEP++ +D + +W + EE+++ K ++L SHS
Sbjct: 2142 CSYGTKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQN-KCSVILTSHS 2200
Query: 285 QDFLNGVCTNIVHM 298
+ +CT + M
Sbjct: 2201 MEECEALCTRLAIM 2214
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 18/192 (9%)
Query: 415 NLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--MIRK--------NSHLR-IG 463
N+ GI L+G NGAGK+T+ K+L GD++PS+G +IR +SH +G
Sbjct: 2027 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVG 2086
Query: 464 RYXXXXXXXXXXXXXXXXYM---MKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDG 520
Y + PE +E + K++ R L + S G
Sbjct: 2087 YCPQEDALDDLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRA-TSMCSYG 2145
Query: 521 QRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND---FDGGMVLVSHDFRLIN 577
+ ++ A P +LLLDEP++ +D ++ L I++ ++L SH
Sbjct: 2146 TKRKLSTALALIGKPSILLLDEPSSGMDPKSKRHLWKIISEEVQNKCSVILTSHSMEECE 2205
Query: 578 QVANEIWICENG 589
+ + I NG
Sbjct: 2206 ALCTRLAIMVNG 2217
Score = 31.5 bits (68), Expect = 9.2
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+L+GPNGAGK+T + +L G S G I
Sbjct: 1127 SLLGPNGAGKTTTISMLTGLFGASAGTI 1154
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 48.0 bits (109), Expect = 1e-04
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 25/209 (11%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQ 158
+QD L + G +GL+G+NG GKS+ L EV + H P D L
Sbjct: 4737 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG-EVSLTSG----HAIIRTPMGDAVDLS 4791
Query: 159 CVMEVDEERVKLEKLAEMLAHCEDDESQEQLMD------VYDRLDDLSADTAEARAANIL 212
++ +C ++ ++L+ Y L + A +++
Sbjct: 4792 SAGTA----------GVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLI 4841
Query: 213 HGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L K +SGG + +++ A AL KP +LLLDEP++ +D + +L + +
Sbjct: 4842 RRLHLEAHAD-KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIM 4900
Query: 273 HYKR---ILVLISHSQDFLNGVCTNIVHM 298
R VL SHS + +CT + M
Sbjct: 4901 KEVREGCAAVLTSHSMEECEALCTRLAIM 4929
Score = 34.3 bits (75), Expect = 1.3
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 222 QQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK--RILV 279
Q K T+ SGG + +++L A ++LDEPT+ +D + L + L Y+ R ++
Sbjct: 3969 QHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTII 4028
Query: 280 LISHSQDFLNGVCTNIVHMSKRRLK 304
+H D + + + RL+
Sbjct: 4029 FTTHHLDEAEALSDRVAVLQHGRLR 4053
Score = 33.1 bits (72), Expect = 3.0
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 412 IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+ ++L D AL+G NGAGK+T++ +L G P++G I
Sbjct: 3857 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI 3899
Score = 33.1 bits (72), Expect = 3.0
Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 389 GKVPPPVIMVQNVSFRYTDSGPWIY--KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGD 446
G+ ++++ N+S Y I +++ GI L+G NGAGKST K+L G+
Sbjct: 4711 GRTNGDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGE 4770
Query: 447 LVPSTG 452
+ ++G
Sbjct: 4771 VSLTSG 4776
>AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ46673 fis, clone TRACH3009061, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 788
Score = 48.0 bits (109), Expect = 1e-04
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 25/209 (11%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQ 158
+QD L + G +GL+G+NG GKS+ L EV + H P D L
Sbjct: 467 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG-EVSLTSG----HAIIRTPMGDAVDLS 521
Query: 159 CVMEVDEERVKLEKLAEMLAHCEDDESQEQLMD------VYDRLDDLSADTAEARAANIL 212
++ +C ++ ++L+ Y L + A +++
Sbjct: 522 SAGTA----------GVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLI 571
Query: 213 HGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L K +SGG + +++ A AL KP +LLLDEP++ +D + +L + +
Sbjct: 572 RRLHLEAHAD-KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIM 630
Query: 273 HYKR---ILVLISHSQDFLNGVCTNIVHM 298
R VL SHS + +CT + M
Sbjct: 631 KEVREGCAAVLTSHSMEECEALCTRLAIM 659
Score = 33.1 bits (72), Expect = 3.0
Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 389 GKVPPPVIMVQNVSFRYTDSGPWIY--KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGD 446
G+ ++++ N+S Y I +++ GI L+G NGAGKST K+L G+
Sbjct: 441 GRTNGDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGE 500
Query: 447 LVPSTG 452
+ ++G
Sbjct: 501 VSLTSG 506
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 48.0 bits (109), Expect = 1e-04
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 25/209 (11%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQ 158
+QD L + G +GL+G+NG GKS+ L EV + H P D L
Sbjct: 1806 VQDISLGIPKGECFGLLGVNGAGKSTTFKMLNG-EVSLTSG----HAIIRTPMGDAVDLS 1860
Query: 159 CVMEVDEERVKLEKLAEMLAHCEDDESQEQLMD------VYDRLDDLSADTAEARAANIL 212
++ +C ++ ++L+ Y L + A +++
Sbjct: 1861 SAGTA----------GVLIGYCPQQDALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLI 1910
Query: 213 HGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELK 272
L K +SGG + +++ A AL KP +LLLDEP++ +D + +L + +
Sbjct: 1911 RRLHLEAHAD-KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIM 1969
Query: 273 HYKR---ILVLISHSQDFLNGVCTNIVHM 298
R VL SHS + +CT + M
Sbjct: 1970 KEVREGCAAVLTSHSMEECEALCTRLAIM 1998
Score = 34.3 bits (75), Expect = 1.3
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 222 QQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK--RILV 279
Q K T+ SGG + +++L A ++LDEPT+ +D + L + L Y+ R ++
Sbjct: 1037 QHKQTRALSGGLKRKLSLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKYREGRTII 1096
Query: 280 LISHSQDFLNGVCTNIVHMSKRRLK 304
+H D + + + RL+
Sbjct: 1097 FTTHHLDEAEALSDRVAVLQHGRLR 1121
Score = 33.1 bits (72), Expect = 3.0
Identities = 16/43 (37%), Positives = 26/43 (60%)
Query: 412 IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+ ++L D AL+G NGAGK+T++ +L G P++G I
Sbjct: 925 VVQDLSLTFYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTI 967
Score = 33.1 bits (72), Expect = 3.0
Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 389 GKVPPPVIMVQNVSFRYTDSGPWIY--KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGD 446
G+ ++++ N+S Y I +++ GI L+G NGAGKST K+L G+
Sbjct: 1780 GRTNGDILVLYNLSKHYRRFFQNIIAVQDISLGIPKGECFGLLGVNGAGKSTTFKMLNGE 1839
Query: 447 LVPSTG 452
+ ++G
Sbjct: 1840 VSLTSG 1845
>AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 48.0 bits (109), Expect = 1e-04
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 109 GRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEVDEER- 167
G +GL+G+NG GK++ L D + + + K+ L + EV +
Sbjct: 1965 GECFGLLGVNGAGKTTTFKMLTG---------DNTVTSGDATVAGKSILTNISEVHQNMG 2015
Query: 168 --VKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKA 225
+ + + E+L +E L +Y RL + A+ E A + LG T A
Sbjct: 2016 YCPQFDAIDELLT------GREHLY-LYARLRGVPAEEIEKVANWSIKSLGLTVYADCLA 2068
Query: 226 TKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLIS 282
+SGG + +++ A AL P L+LLDEPT +D A +W + + R +VL S
Sbjct: 2069 GT-YSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNVIVSIIREGRAVVLTS 2127
Query: 283 HSQDFLNGVCTNIVHMSK 300
HS + +CT + M K
Sbjct: 2128 HSMEECEALCTRLAIMVK 2145
Score = 37.1 bits (82), Expect = 0.19
Identities = 29/118 (24%), Positives = 61/118 (51%), Gaps = 4/118 (3%)
Query: 193 YDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLL 252
Y +L S + A+ +L G + ++A +D SGG + ++++A A +++L
Sbjct: 1027 YAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEA-QDLSGGMQRKLSVAIAFVGDAKVVIL 1085
Query: 253 DEPTNHLDLDACVWLEEELKHYK--RILVLISHSQDFLNGVCTNIVHMSKRRLKYYTG 308
DEPT+ +D + + + L Y+ R +++ +H D + + I +++ RL Y +G
Sbjct: 1086 DEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIIAQGRL-YCSG 1142
Score = 33.9 bits (74), Expect = 1.7
Identities = 20/61 (32%), Positives = 31/61 (50%)
Query: 394 PVIMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
P + V+N+ + SG L + A +G NGAGK+T L +L G L P++G
Sbjct: 927 PGVCVKNLVKIFEPSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGT 986
Query: 454 I 454
+
Sbjct: 987 V 987
>M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic
fibrosis mRNA, encoding a presumed transmembrane
conductance regulator (CFTR). ).
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 419 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 478
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 479 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 538
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 539 SLARAVYKDADLYLLDSPFGYLDVLT 564
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1194 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1236
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 531 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 562
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1205 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1241
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1329 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1359
>DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 419 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 478
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 479 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 538
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 539 SLARAVYKDADLYLLDSPFGYLDVLT 564
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1194 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1236
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 531 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 562
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1205 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1241
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1329 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1359
>DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>AY032599-1|AAK39642.1| 1463|Homo sapiens multidrug
resistance-associated protein 7 protein.
Length = 1463
Score = 47.2 bits (107), Expect = 2e-04
Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 24/161 (14%)
Query: 104 LELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTALQCVMEV 163
LE+ G G VG GCGKSSLLAA+ + H+ + L++ +
Sbjct: 592 LEVKKGMLVGTVGKVGCGKSSLLAAIAGELHRLRGHVAVRGLSKGFG----------LAT 641
Query: 164 DEERVKLEKLAEMLAHCEDDESQ--EQLMDVYDRLDDLSADTAEARAANILHGLGFTKEM 221
E ++ + + + + ++Q +++++ DDLS A G E+
Sbjct: 642 QEPWIQFATIRDNILFGKTFDAQLYKEVLEACALNDDLSILPA-----------GDQTEV 690
Query: 222 QQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLD 262
+K SGG R RIALARA+Y + L LLD+P +D D
Sbjct: 691 GEKGVT-LSGGQRARIALARAVYQEKELYLLDDPLAAVDAD 730
Score = 34.3 bits (75), Expect = 1.3
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 399 QNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
Q+V Y P + F + ++ +VG G+GKS+LL +L+ L PS+G +
Sbjct: 1220 QDVVLAYRPGLPNALDGVTFCVQPGEKVGIVGRTGSGKSSLLLVLFRLLEPSSGRV 1275
>AK074738-1|BAC11171.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ90257 fis, clone NT2RM4000444, weakly similar to
ANTIGEN PEPTIDE TRANSPORTER 1. ).
Length = 472
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 16/217 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 199 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 258
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 259 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 309
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 310 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 368
Query: 249 LLLLDEPTNHLDLDACVWLEEEL--KHYKRILVLISH 283
+L+LDE T+ LD ++ +++ + K +++I+H
Sbjct: 369 VLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 405
Score = 34.7 bits (76), Expect = 0.99
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIN 560
QLS GQ+ RV A + P +L+LDE T+ LD E+ + AI+
Sbjct: 348 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH 392
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 213 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 258
>AF216494-1|AAF89993.1| 766|Homo sapiens ATP-binding cassette
protein ABCB9 protein.
Length = 766
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 16/217 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 493 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 553 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 603
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 604 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 662
Query: 249 LLLLDEPTNHLDLDACVWLEEEL--KHYKRILVLISH 283
+L+LDE T+ LD ++ +++ + K +++I+H
Sbjct: 663 VLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 699
Score = 34.7 bits (76), Expect = 0.99
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIN 560
QLS GQ+ RV A + P +L+LDE T+ LD E+ + AI+
Sbjct: 642 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH 686
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 507 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
>AF061324-1|AAC16058.1| 1549|Homo sapiens sulfonylurea receptor 2B
protein.
Length = 1549
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 12/211 (5%)
Query: 84 IKIANFSITF-YGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDI 142
IK+ N ++ G L + + + G+ +VG GCGKSSLL A+ + +
Sbjct: 672 IKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHW 731
Query: 143 FHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSAD 202
++ P+ + T + + V L + +E+ + D
Sbjct: 732 SNVNESEPSFEATRSR-----NRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTD 786
Query: 203 TAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLD 262
+ L G E+ ++ + SGG R RI +ARALY +++ LD+P + LD+
Sbjct: 787 ACSLQPDIDLLPFGDQTEIGERGI-NLSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 845
Query: 263 ACVWLEEE-----LKHYKRILVLISHSQDFL 288
L +E L+ KR LVL++H +L
Sbjct: 846 LSDHLMQEGILKFLQDDKRTLVLVTHKLQYL 876
Score = 32.3 bits (70), Expect = 5.3
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L + D +VLV+H
Sbjct: 812 LSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTH 871
Query: 572 DFRLI 576
+ +
Sbjct: 872 KLQYL 876
>AF061323-1|AAC16057.1| 1549|Homo sapiens sulfonylurea receptor 2A
protein.
Length = 1549
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 12/211 (5%)
Query: 84 IKIANFSITF-YGSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDI 142
IK+ N ++ G L + + + G+ +VG GCGKSSLL A+ + +
Sbjct: 672 IKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHW 731
Query: 143 FHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSAD 202
++ P+ + T + + V L + +E+ + D
Sbjct: 732 SNVNESEPSFEATRSR-----NRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTD 786
Query: 203 TAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLD 262
+ L G E+ ++ + SGG R RI +ARALY +++ LD+P + LD+
Sbjct: 787 ACSLQPDIDLLPFGDQTEIGERGI-NLSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 845
Query: 263 ACVWLEEE-----LKHYKRILVLISHSQDFL 288
L +E L+ KR LVL++H +L
Sbjct: 846 LSDHLMQEGILKFLQDDKRTLVLVTHKLQYL 876
Score = 32.3 bits (70), Expect = 5.3
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L + D +VLV+H
Sbjct: 812 LSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTH 871
Query: 572 DFRLI 576
+ +
Sbjct: 872 KLQYL 876
>AB177852-1|BAD66830.1| 796|Homo sapiens KIAA1520 splice variant 1
protein.
Length = 796
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 16/217 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 523 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 582
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 583 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 633
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 634 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 692
Query: 249 LLLLDEPTNHLDLDACVWLEEEL--KHYKRILVLISH 283
+L+LDE T+ LD ++ +++ + K +++I+H
Sbjct: 693 VLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 729
Score = 34.7 bits (76), Expect = 0.99
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIN 560
QLS GQ+ RV A + P +L+LDE T+ LD E+ + AI+
Sbjct: 672 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH 716
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 537 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 582
>AB045381-1|BAA97989.2| 766|Homo sapiens TAPL protein.
Length = 766
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 16/217 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 493 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 553 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 603
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 604 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 662
Query: 249 LLLLDEPTNHLDLDACVWLEEEL--KHYKRILVLISH 283
+L+LDE T+ LD ++ +++ + K +++I+H
Sbjct: 663 VLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 699
Score = 34.7 bits (76), Expect = 0.99
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIN 560
QLS GQ+ RV A + P +L+LDE T+ LD E+ + AI+
Sbjct: 642 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH 686
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 507 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
>AB040953-1|BAA96044.2| 810|Homo sapiens KIAA1520 protein protein.
Length = 810
Score = 47.2 bits (107), Expect = 2e-04
Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 16/217 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 537 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 596
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 597 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 647
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 648 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 706
Query: 249 LLLLDEPTNHLDLDACVWLEEEL--KHYKRILVLISH 283
+L+LDE T+ LD ++ +++ + K +++I+H
Sbjct: 707 VLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAH 743
Score = 34.7 bits (76), Expect = 0.99
Identities = 19/45 (42%), Positives = 27/45 (60%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIN 560
QLS GQ+ RV A + P +L+LDE T+ LD E+ + AI+
Sbjct: 686 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH 730
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 551 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 596
>DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
>DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
>AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 46.8 bits (106), Expect = 2e-04
Identities = 51/210 (24%), Positives = 90/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E LQ ++ G+ ++G NG GKS+LL L V I++ T
Sbjct: 408 EALQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYN----------TQ 457
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R + + + +E L V+ ++ + E I+ L
Sbjct: 458 LSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLR-VFAKIKGIQPKEVEQEVKRIIMELD 516
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK- 275
+ +Q K SGG + ++ L A+ P +LLLDEPT LD + + LK +K
Sbjct: 517 M-QSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLKEHKV 575
Query: 276 -RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
R+++ + D + + V +S +LK
Sbjct: 576 DRLILFSTQFMDEADILADRKVFLSNGKLK 605
Score = 41.9 bits (94), Expect = 0.007
Identities = 53/217 (24%), Positives = 92/217 (42%), Gaps = 23/217 (10%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI-----RKNSHLRIGRYXXX 468
+N+ F + L L+G NGAGKST +K++ G P+ G++ R + +
Sbjct: 1223 RNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKF 1282
Query: 469 XXXXXXXXXXXXXYMMKEFPEVRE------REEMRKIIGRY--GLTGRQQV-CPMRQLSD 519
MKE E+ +E+ I R L ++Q+ P++ LS+
Sbjct: 1283 LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSE 1342
Query: 520 GQRCRVVFAWLAWQTPHLLLLDEPTNHLDME----TIDALADAINDFDGGMVLVSHDFRL 575
G + ++ F P ++LLDEP +D E L + + + G +L +H
Sbjct: 1343 GIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSE 1402
Query: 576 INQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
V + + + +G T + G I HLK+K +D
Sbjct: 1403 AEAVCDRMAMMVSG-TLRCIGSI----QHLKNKFGRD 1434
Score = 37.1 bits (82), Expect = 0.19
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGM----------------IRKNSHLRIGRYXXXXX 470
A++G NGAGKSTLL +L G V + G IRKN ++
Sbjct: 424 AILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGF-CPQFNFQFD 482
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWL 530
+K +E+++II + Q + ++LS GQ+ ++
Sbjct: 483 FLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIA-KKLSGGQKRKLTLGIA 541
Query: 531 AWQTPHLLLLDEPTNHLD 548
P +LLLDEPT LD
Sbjct: 542 ILGDPQVLLLDEPTAGLD 559
>AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 46.8 bits (106), Expect = 2e-04
Identities = 51/210 (24%), Positives = 90/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E LQ ++ G+ ++G NG GKS+LL L V I++ T
Sbjct: 408 EALQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYN----------TQ 457
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R + + + +E L V+ ++ + E I+ L
Sbjct: 458 LSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLR-VFAKIKGIQPKEVEQEVKRIIMELD 516
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK- 275
+ +Q K SGG + ++ L A+ P +LLLDEPT LD + + LK +K
Sbjct: 517 M-QSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLKEHKV 575
Query: 276 -RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
R+++ + D + + V +S +LK
Sbjct: 576 DRLILFSTQFMDEADILADRKVFLSNGKLK 605
Score = 41.9 bits (94), Expect = 0.007
Identities = 53/217 (24%), Positives = 92/217 (42%), Gaps = 23/217 (10%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI-----RKNSHLRIGRYXXX 468
+N+ F + L L+G NGAGKST +K++ G P+ G++ R + +
Sbjct: 1223 RNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKF 1282
Query: 469 XXXXXXXXXXXXXYMMKEFPEVRE------REEMRKIIGRY--GLTGRQQV-CPMRQLSD 519
MKE E+ +E+ I R L ++Q+ P++ LS+
Sbjct: 1283 LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSE 1342
Query: 520 GQRCRVVFAWLAWQTPHLLLLDEPTNHLDME----TIDALADAINDFDGGMVLVSHDFRL 575
G + ++ F P ++LLDEP +D E L + + + G +L +H
Sbjct: 1343 GIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSE 1402
Query: 576 INQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
V + + + +G T + G I HLK+K +D
Sbjct: 1403 AEAVCDRMAMMVSG-TLRCIGSI----QHLKNKFGRD 1434
Score = 37.1 bits (82), Expect = 0.19
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGM----------------IRKNSHLRIGRYXXXXX 470
A++G NGAGKSTLL +L G V + G IRKN ++
Sbjct: 424 AILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGF-CPQFNFQFD 482
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWL 530
+K +E+++II + Q + ++LS GQ+ ++
Sbjct: 483 FLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIA-KKLSGGQKRKLTLGIA 541
Query: 531 AWQTPHLLLLDEPTNHLD 548
P +LLLDEPT LD
Sbjct: 542 ILGDPQVLLLDEPTAGLD 559
>AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A10
protein.
Length = 1543
Score = 46.8 bits (106), Expect = 2e-04
Identities = 51/210 (24%), Positives = 90/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E LQ ++ G+ ++G NG GKS+LL L V I++ T
Sbjct: 408 EALQGIFFDIYEGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYN----------TQ 457
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R + + + +E L V+ ++ + E I+ L
Sbjct: 458 LSEITDMEEIRKNIGFCPQFNFQFDFLTVRENLR-VFAKIKGIQPKEVEQEVKRIIMELD 516
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK- 275
+ +Q K SGG + ++ L A+ P +LLLDEPT LD + + LK +K
Sbjct: 517 M-QSIQDIIAKKLSGGQKRKLTLGIAILGDPQVLLLDEPTAGLDPFSRHRVWSLLKEHKV 575
Query: 276 -RILVLISHSQDFLNGVCTNIVHMSKRRLK 304
R+++ + D + + V +S +LK
Sbjct: 576 DRLILFSTQFMDEADILADRKVFLSNGKLK 605
Score = 41.9 bits (94), Expect = 0.007
Identities = 53/217 (24%), Positives = 92/217 (42%), Gaps = 23/217 (10%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI-----RKNSHLRIGRYXXX 468
+N+ F + L L+G NGAGKST +K++ G P+ G++ R + +
Sbjct: 1223 RNVSFCVKKGEVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKF 1282
Query: 469 XXXXXXXXXXXXXYMMKEFPEVRE------REEMRKIIGRY--GLTGRQQV-CPMRQLSD 519
MKE E+ +E+ I R L ++Q+ P++ LS+
Sbjct: 1283 LGYCPQENSLWPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSE 1342
Query: 520 GQRCRVVFAWLAWQTPHLLLLDEPTNHLDME----TIDALADAINDFDGGMVLVSHDFRL 575
G + ++ F P ++LLDEP +D E L + + + G +L +H
Sbjct: 1343 GIKRKLCFVLSILGNPSVVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSE 1402
Query: 576 INQVANEIWICENGTTTKWEGGILKYKDHLKSKILKD 612
V + + + +G T + G I HLK+K +D
Sbjct: 1403 AEAVCDRMAMMVSG-TLRCIGSI----QHLKNKFGRD 1434
Score = 37.1 bits (82), Expect = 0.19
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGM----------------IRKNSHLRIGRYXXXXX 470
A++G NGAGKSTLL +L G V + G IRKN ++
Sbjct: 424 AILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGF-CPQFNFQFD 482
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWL 530
+K +E+++II + Q + ++LS GQ+ ++
Sbjct: 483 FLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIA-KKLSGGQKRKLTLGIA 541
Query: 531 AWQTPHLLLLDEPTNHLD 548
P +LLLDEPT LD
Sbjct: 542 ILGDPQVLLLDEPTAGLD 559
>AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens
cDNA FLJ23973 fis, clone HEP18305, highly similar to
ATP-binding cassette, sub-family B, member 6,
mitochondrial precursor. ).
Length = 571
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 319 IEFENVHFSYAD-GRETLQDVSFTVMPEQTLALVGPSGAGKSTILRLLFLFYDISSGCIR 377
Score = 37.1 bits (82), Expect = 0.19
Identities = 17/45 (37%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G+ ++ ++ K SGG + R+A+AR + P ++LLDE T+ LD
Sbjct: 444 GYRTQVGERGLK-LSGGEKQRVAIARTILKAPGIILLDEATSALD 487
>AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/211 (25%), Positives = 89/211 (42%), Gaps = 17/211 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG-MIRKNS--HLRIGRYXXXXX 470
+N+ F + + L+G NGAGKST +K++ GD P+ G +I K S +G
Sbjct: 1310 RNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQ 1369
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGR-----QQVCPMRQLSDGQRCRV 525
++ + V+ + +I L Q P++ LS+G + ++
Sbjct: 1370 ENALWPNLTVRQHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKL 1429
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAI----NDFDGGMVLVSHDFRLINQVAN 581
F P ++LLDEP+ +D E + I + + G +L +H V +
Sbjct: 1430 CFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCD 1489
Query: 582 EIWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLKSK KD
Sbjct: 1490 RVAIMVSG-RLRCIGSI----QHLKSKFGKD 1515
Score = 42.7 bits (96), Expect = 0.004
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 388 CGKVPPPVIMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYG 445
CGK I ++N+ Y + K + F I AL+G +GAGK+TLL +L G
Sbjct: 476 CGK---EAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSG 532
Query: 446 DLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE------------- 492
VP++G + +H + R + F V+E
Sbjct: 533 LSVPTSGSVTVYNH-TLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILP 591
Query: 493 ---REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+E+++++ + Q + + LS GQ ++ F P +LLLDEPT LD
Sbjct: 592 HEVEKEVQRVVQELEMENIQDIL-AQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLD 649
Score = 38.3 bits (85), Expect = 0.080
Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 16/181 (8%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + G E L+ + ++ G+ L+G +G GK++LL L VP
Sbjct: 481 IRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS 540
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDL 199
+ +++ T A + + + V+ L + ++ + ++ ++ +
Sbjct: 541 VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL-----------TVKENLRLFAKIKGI 589
Query: 200 SADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHL 259
E ++ L + +Q ++ SGG ++ A+ P +LLLDEPT L
Sbjct: 590 LPHEVEKEVQRVVQELEM-ENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGL 648
Query: 260 D 260
D
Sbjct: 649 D 649
Score = 32.7 bits (71), Expect = 4.0
Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
Q ++VY + L A ++ L +++ K S G + ++ ++ P
Sbjct: 1381 QHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPV-KTLSEGIKRKLCFVLSILGNP 1439
Query: 248 HLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRL 303
++LLDEP+ +D + +W + ++ +R +L +H VC + M RL
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1499
Query: 304 K 304
+
Sbjct: 1500 R 1500
>AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/211 (25%), Positives = 89/211 (42%), Gaps = 17/211 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG-MIRKNS--HLRIGRYXXXXX 470
+N+ F + + L+G NGAGKST +K++ GD P+ G +I K S +G
Sbjct: 1310 RNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQ 1369
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGR-----QQVCPMRQLSDGQRCRV 525
++ + V+ + +I L Q P++ LS+G + ++
Sbjct: 1370 ENALWPNLTVRQHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKL 1429
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAI----NDFDGGMVLVSHDFRLINQVAN 581
F P ++LLDEP+ +D E + I + + G +L +H V +
Sbjct: 1430 CFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCD 1489
Query: 582 EIWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLKSK KD
Sbjct: 1490 RVAIMVSG-RLRCIGSI----QHLKSKFGKD 1515
Score = 42.7 bits (96), Expect = 0.004
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 388 CGKVPPPVIMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYG 445
CGK I ++N+ Y + K + F I AL+G +GAGK+TLL +L G
Sbjct: 476 CGK---EAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSG 532
Query: 446 DLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE------------- 492
VP++G + +H + R + F V+E
Sbjct: 533 LSVPTSGSVTVYNH-TLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILP 591
Query: 493 ---REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+E+++++ + Q + + LS GQ ++ F P +LLLDEPT LD
Sbjct: 592 HEVEKEVQRVVQELEMENIQDIL-AQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLD 649
Score = 38.3 bits (85), Expect = 0.080
Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 16/181 (8%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + G E L+ + ++ G+ L+G +G GK++LL L VP
Sbjct: 481 IRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS 540
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDL 199
+ +++ T A + + + V+ L + ++ + ++ ++ +
Sbjct: 541 VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL-----------TVKENLRLFAKIKGI 589
Query: 200 SADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHL 259
E ++ L + +Q ++ SGG ++ A+ P +LLLDEPT L
Sbjct: 590 LPHEVEKEVQRVVQELEM-ENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGL 648
Query: 260 D 260
D
Sbjct: 649 D 649
Score = 32.7 bits (71), Expect = 4.0
Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
Q ++VY + L A ++ L +++ K S G + ++ ++ P
Sbjct: 1381 QHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPV-KTLSEGIKRKLCFVLSILGNP 1439
Query: 248 HLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRL 303
++LLDEP+ +D + +W + ++ +R +L +H VC + M RL
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1499
Query: 304 K 304
+
Sbjct: 1500 R 1500
>AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 46.8 bits (106), Expect = 2e-04
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GPNGAGKS+ ++++ G P+ G + HL
Sbjct: 1304 RNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 1363
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 1364 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 1422
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 1423 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 1482
Query: 583 IWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLK+K+ KD
Sbjct: 1483 VAIMVSG-RLRCIGSI----QHLKNKLGKD 1507
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/210 (23%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E L+ L ++ G+ ++G +G GKSSLL L VP + I++
Sbjct: 495 EALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKN---------- 544
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R K+ + D + ++ + ++ ++ + E IL L
Sbjct: 545 LSEMQDLEEIR-KITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELD 603
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHY 274
+ +Q K S G + ++ + P +LLLDEPT LD + VW +
Sbjct: 604 M-QNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRA 662
Query: 275 KRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+++ + S D + + V MS RLK
Sbjct: 663 DHVILFSTQSMDEADILADRKVIMSNGRLK 692
Score = 39.9 bits (89), Expect = 0.026
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV Y + K L F I A++G +GAGKS+LL +L G VP+ G
Sbjct: 478 IRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGS 537
Query: 454 I---RKN-SHLR-IGRYXXXXXXXXXXXXXXXXYMMKE----FPEVR------EREEMRK 498
+ KN S ++ + +KE F +++ +E+++
Sbjct: 538 VTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQR 597
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
I+ + Q + LS+GQ+ ++ F P +LLLDEPT LD
Sbjct: 598 ILLELDMQNIQDNL-AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLD 646
>AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 46.8 bits (106), Expect = 2e-04
Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GPNGAGKS+ ++++ G P+ G + HL
Sbjct: 1304 RNISFCVQEGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 1363
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 1364 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 1422
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 1423 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 1482
Query: 583 IWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLK+K+ KD
Sbjct: 1483 VAIMVSG-RLRCIGSI----QHLKNKLGKD 1507
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/210 (23%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E L+ L ++ G+ ++G +G GKSSLL L VP + I++
Sbjct: 495 EALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKN---------- 544
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R K+ + D + ++ + ++ ++ + E IL L
Sbjct: 545 LSEMQDLEEIR-KITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELD 603
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHY 274
+ +Q K S G + ++ + P +LLLDEPT LD + VW +
Sbjct: 604 M-QNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRA 662
Query: 275 KRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+++ + S D + + V MS RLK
Sbjct: 663 DHVILFSTQSMDEADILADRKVIMSNGRLK 692
Score = 39.9 bits (89), Expect = 0.026
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV Y + K L F I A++G +GAGKS+LL +L G VP+ G
Sbjct: 478 IRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGS 537
Query: 454 I---RKN-SHLR-IGRYXXXXXXXXXXXXXXXXYMMKE----FPEVR------EREEMRK 498
+ KN S ++ + +KE F +++ +E+++
Sbjct: 538 VTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQR 597
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
I+ + Q + LS+GQ+ ++ F P +LLLDEPT LD
Sbjct: 598 ILLELDMQNIQDNL-AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLD 646
>AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein.
Length = 996
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHLRI-GRYX- 466
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + + ++
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSGRISFCSQFSW 496
Query: 467 XXXXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGRQQVCPMR-QLSDGQRCRV 525
Y + V + ++ + I ++ + LS GQR R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMET 551
A ++ L LLD P +LD+ T
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLT 582
Score = 37.5 bits (83), Expect = 0.14
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
SGG R RI+LARA+Y L LLD P +LD+
Sbjct: 549 SGGQRARISLARAVYKDADLYLLDSPFGYLDV 580
>BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/210 (23%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E L+ L ++ G+ ++G +G GKSSLL L VP + I++
Sbjct: 495 EALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKN---------- 544
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R K+ + D + ++ + ++ ++ + E IL L
Sbjct: 545 LSEMQDLEEIR-KITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELD 603
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHY 274
+ +Q K S G + ++ + P +LLLDEPT LD + VW +
Sbjct: 604 M-QNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRA 662
Query: 275 KRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+++ + S D + + V MS RLK
Sbjct: 663 DHVILFSTQSMDEADILADRKVIMSNGRLK 692
Score = 41.1 bits (92), Expect = 0.011
Identities = 38/187 (20%), Positives = 80/187 (42%), Gaps = 12/187 (6%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GP+GAGKS+ ++++ G P+ G + HL
Sbjct: 1304 RNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 1363
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 1364 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 1422
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 1423 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 1482
Query: 583 IWICENG 589
+ I +G
Sbjct: 1483 VAIMVSG 1489
Score = 39.9 bits (89), Expect = 0.026
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV Y + K L F I A++G +GAGKS+LL +L G VP+ G
Sbjct: 478 IRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGS 537
Query: 454 I---RKN-SHLR-IGRYXXXXXXXXXXXXXXXXYMMKE----FPEVR------EREEMRK 498
+ KN S ++ + +KE F +++ +E+++
Sbjct: 538 VTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQR 597
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
I+ + Q + LS+GQ+ ++ F P +LLLDEPT LD
Sbjct: 598 ILLELDMQNIQDNL-AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLD 646
>BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/210 (23%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E L+ L ++ G+ ++G +G GKSSLL L VP + I++
Sbjct: 495 EALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKN---------- 544
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R K+ + D + ++ + ++ ++ + E IL L
Sbjct: 545 LSEMQDLEEIR-KITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELD 603
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHY 274
+ +Q K S G + ++ + P +LLLDEPT LD + VW +
Sbjct: 604 M-QNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRA 662
Query: 275 KRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+++ + S D + + V MS RLK
Sbjct: 663 DHVILFSTQSMDEADILADRKVIMSNGRLK 692
Score = 41.1 bits (92), Expect = 0.011
Identities = 38/187 (20%), Positives = 80/187 (42%), Gaps = 12/187 (6%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GP+GAGKS+ ++++ G P+ G + HL
Sbjct: 1304 RNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 1363
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 1364 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 1422
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 1423 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 1482
Query: 583 IWICENG 589
+ I +G
Sbjct: 1483 VAIMVSG 1489
Score = 39.9 bits (89), Expect = 0.026
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV Y + K L F I A++G +GAGKS+LL +L G VP+ G
Sbjct: 478 IRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGS 537
Query: 454 I---RKN-SHLR-IGRYXXXXXXXXXXXXXXXXYMMKE----FPEVR------EREEMRK 498
+ KN S ++ + +KE F +++ +E+++
Sbjct: 538 VTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQR 597
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
I+ + Q + LS+GQ+ ++ F P +LLLDEPT LD
Sbjct: 598 ILLELDMQNIQDNL-AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLD 646
>BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein.
Length = 301
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 49 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 107
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 28 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 87
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 88 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 145
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 146 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 196
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 197 ARTILKAPGIILLDEATSALD 217
>BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 6 protein.
Length = 842
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 590 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 648
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 569 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 628
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 629 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 686
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 687 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 737
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 738 ARTILKAPGIILLDEATSALD 758
>AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6
protein.
Length = 1617
Score = 46.4 bits (105), Expect = 3e-04
Identities = 49/210 (23%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTA 156
E L+ L ++ G+ ++G +G GKSSLL L VP + I++
Sbjct: 495 EALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGSVTIYNKN---------- 544
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
L + +++E R K+ + D + ++ + ++ ++ + E IL L
Sbjct: 545 LSEMQDLEEIR-KITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQRILLELD 603
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVWLEEELKHY 274
+ +Q K S G + ++ + P +LLLDEPT LD + VW +
Sbjct: 604 M-QNIQDNLAKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLDPFSRDQVWSLLRERRA 662
Query: 275 KRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+++ + S D + + V MS RLK
Sbjct: 663 DHVILFSTQSMDEADILADRKVIMSNGRLK 692
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GP+GAGKS+ ++++ G P+ G + HL
Sbjct: 1304 RNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 1363
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 1364 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 1422
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 1423 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 1482
Query: 583 IWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLK+K+ KD
Sbjct: 1483 VAIMVSG-RLRCIGSI----QHLKNKLGKD 1507
Score = 39.9 bits (89), Expect = 0.026
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV Y + K L F I A++G +GAGKS+LL +L G VP+ G
Sbjct: 478 IRIRNVKKEYKGKSGKVEALKGLLFDIYEGQITAILGHSGAGKSSLLNILNGLSVPTEGS 537
Query: 454 I---RKN-SHLR-IGRYXXXXXXXXXXXXXXXXYMMKE----FPEVR------EREEMRK 498
+ KN S ++ + +KE F +++ +E+++
Sbjct: 538 VTIYNKNLSEMQDLEEIRKITGVCPQFNVQFDILTVKENLSLFAKIKGIHLKEVEQEVQR 597
Query: 499 IIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
I+ + Q + LS+GQ+ ++ F P +LLLDEPT LD
Sbjct: 598 ILLELDMQNIQDNL-AKHLSEGQKRKLTFGITILGDPQILLLDEPTTGLD 646
>AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ32464 fis, clone SKNMC1000251, highly similar to
Homo sapiens MT-ABC transporter (MTABC) mRNA. ).
Length = 766
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 514 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 572
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 493 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 552
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 553 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 610
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 611 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 661
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 662 ARTILKAPGIILLDEATSALD 682
>AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat
protein.
Length = 842
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 590 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 648
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 569 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 628
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 629 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 686
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 687 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 737
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 738 ARTILKAPGIILLDEATSALD 758
>AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette
half-transporter protein.
Length = 896
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 644 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 702
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 623 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 682
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 683 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 740
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 741 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 791
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 792 ARTILKAPGIILLDEATSALD 812
>AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter
protein.
Length = 842
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 590 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 648
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 569 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 628
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 629 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 686
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 687 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 737
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 738 ARTILKAPGIILLDEATSALD 758
>AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein.
Length = 511
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 259 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 317
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 238 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 297
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 298 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 355
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 356 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 406
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 407 ARTILKAPGIILLDEATSALD 427
>AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC
transporter 3 protein.
Length = 842
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/60 (45%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIR 455
I +NV F Y D G +++ F + LALVGP+GAGKST+L+LL+ S+G IR
Sbjct: 590 IEFENVHFSYAD-GRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIR 648
Score = 43.2 bits (97), Expect = 0.003
Identities = 47/201 (23%), Positives = 94/201 (46%), Gaps = 14/201 (6%)
Query: 63 KMNSEARSCTGSLAVHPRSRDIKIANFSITFY-GSELLQDTLLELNCGRRYGLVGLNGCG 121
K +E + G+ + + I+ N ++ G E LQD + G+ LVG +G G
Sbjct: 569 KEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAG 628
Query: 122 KSSLLAALGR-REVPIP-EHIDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAH 179
KS++L L R ++ ID +++ AS ++ + V + + + + +A+ + +
Sbjct: 629 KSTILRLLFRFYDISSGCIRIDGQDISQVTQASLRSHIGVVPQ--DTVLFNDTIADNIRY 686
Query: 180 CEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIAL 239
+++ + +A A A + G+ ++ ++ K SGG + R+A+
Sbjct: 687 GRVTAGNDEV--------EAAAQAAGIHDAIMAFPEGYRTQVGERGLK-LSGGEKQRVAI 737
Query: 240 ARALYVKPHLLLLDEPTNHLD 260
AR + P ++LLDE T+ LD
Sbjct: 738 ARTILKAPGIILLDEATSALD 758
>X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.
Length = 1704
Score = 46.0 bits (104), Expect = 4e-04
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 145 LTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSA 201
LT P + A E+ ++ V++ K + + D+ + + + Y +L LS
Sbjct: 579 LTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR 638
Query: 202 DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
+LH +G + ++ + SGG R ++++ AL +L+LDEPT+ +D
Sbjct: 639 QKCPEEVKQMLHIIGLEDKWNSRS-RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDA 697
Query: 262 DA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+ +W + + R +VL +H D + + I M+K L+
Sbjct: 698 ISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQ 742
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 182 DDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALAR 241
D + +++ +Y RL + A N L GL + K + +SGG + +++
Sbjct: 1469 DHMTGREMLVMYARLRGIPERHIGACVENTLRGL-LLEPHANKLVRTYSGGNKRKLSTGI 1527
Query: 242 ALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLISHSQDFLNGVCTNIVHM 298
AL +P ++ LDEP+ +D A +W + + +++ SHS + +CT + M
Sbjct: 1528 ALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIM 1587
Query: 299 SKRRLK 304
+ + K
Sbjct: 1588 VQGQFK 1593
>U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.
Length = 1704
Score = 46.0 bits (104), Expect = 4e-04
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 145 LTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSA 201
LT P + A E+ ++ V++ K + + D+ + + + Y +L LS
Sbjct: 579 LTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR 638
Query: 202 DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
+LH +G + ++ + SGG R ++++ AL +L+LDEPT+ +D
Sbjct: 639 QKCPEEVKQMLHIIGLEDKWNSRS-RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDA 697
Query: 262 DA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+ +W + + R +VL +H D + + I M+K L+
Sbjct: 698 ISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQ 742
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 182 DDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALAR 241
D + +++ +Y RL + A N L GL + K + +SGG + +++
Sbjct: 1469 DHMTGREMLVMYARLRGIPERHIGACVENTLRGL-LLEPHANKLVRTYSGGNKRKLSTGI 1527
Query: 242 ALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLISHSQDFLNGVCTNIVHM 298
AL +P ++ LDEP+ +D A +W + + +++ SHS + +CT + M
Sbjct: 1528 ALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIM 1587
Query: 299 SKRRLK 304
+ + K
Sbjct: 1588 VQGQFK 1593
>DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), member 3 protein.
Length = 1704
Score = 46.0 bits (104), Expect = 4e-04
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 145 LTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSA 201
LT P + A E+ ++ V++ K + + D+ + + + Y +L LS
Sbjct: 579 LTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR 638
Query: 202 DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
+LH +G + ++ + SGG R ++++ AL +L+LDEPT+ +D
Sbjct: 639 QKCPEEVKQMLHIIGLEDKWNSRS-RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDA 697
Query: 262 DA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+ +W + + R +VL +H D + + I M+K L+
Sbjct: 698 ISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQ 742
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 182 DDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALAR 241
D + +++ +Y RL + A N L GL + K + +SGG + +++
Sbjct: 1469 DHMTGREMLVMYARLRGIPERHIGACVENTLRGL-LLEPHANKLVRTYSGGNKRKLSTGI 1527
Query: 242 ALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLISHSQDFLNGVCTNIVHM 298
AL +P ++ LDEP+ +D A +W + + +++ SHS + +CT + M
Sbjct: 1528 ALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIM 1587
Query: 299 SKRRLK 304
+ + K
Sbjct: 1588 VQGQFK 1593
>BC141836-1|AAI41837.1| 693|Homo sapiens Unknown (protein for
MGC:165100) protein.
Length = 693
Score = 46.0 bits (104), Expect = 4e-04
Identities = 52/180 (28%), Positives = 88/180 (48%), Gaps = 14/180 (7%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G E+L+D L L G+ LVG +G GK+++ + L R P + + R++ D
Sbjct: 469 GFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDG--RDLRTLDP 526
Query: 155 TAL--QCVMEVDEERVKL-EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANI 211
+ L Q V + +E V + E + + + S E+ VY +A A A
Sbjct: 527 SWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEE---VYT-----AAREANAHEFIT 578
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEEL 271
G+ + ++ T SGG + R+A+ARAL +P +L+LDE T+ LD ++ ++E L
Sbjct: 579 SFPEGYNTVVGERGTT-LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEAL 637
Score = 33.1 bits (72), Expect = 3.0
Identities = 17/54 (31%), Positives = 31/54 (57%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVS 570
LS GQ+ R+ A + P +L+LDE T+ LD E+ + +A++ G +++
Sbjct: 595 LSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLA 648
>AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9
protein.
Length = 1624
Score = 46.0 bits (104), Expect = 4e-04
Identities = 53/211 (25%), Positives = 89/211 (42%), Gaps = 17/211 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG-MIRKNS--HLRIGRYXXXXX 470
+N+ F + + L+G NGAGKST +K++ GD P+ G +I K S +G
Sbjct: 1310 RNVSFCVKKGEVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQ 1369
Query: 471 XXXXXXXXXXXYMMKEFPEVREREEMRKIIGRYGLTGR-----QQVCPMRQLSDGQRCRV 525
++ + V+ + +I L Q P++ LS+G + ++
Sbjct: 1370 ENALWPNLTVRQHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKL 1429
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAI----NDFDGGMVLVSHDFRLINQVAN 581
F P ++LLDEP+ +D E + I + + G +L +H V +
Sbjct: 1430 RFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCD 1489
Query: 582 EIWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLKSK KD
Sbjct: 1490 RVAIMVSG-RLRCIGSI----QHLKSKFGKD 1515
Score = 42.7 bits (96), Expect = 0.004
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 388 CGKVPPPVIMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYG 445
CGK I ++N+ Y + K + F I AL+G +GAGK+TLL +L G
Sbjct: 476 CGK---EAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSG 532
Query: 446 DLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE------------- 492
VP++G + +H + R + F V+E
Sbjct: 533 LSVPTSGSVTVYNH-TLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILP 591
Query: 493 ---REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+E+++++ + Q + + LS GQ ++ F P +LLLDEPT LD
Sbjct: 592 HEVEKEVQRVVQELEMENIQDIL-AQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLD 649
Score = 38.3 bits (85), Expect = 0.080
Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 16/181 (8%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + G E L+ + ++ G+ L+G +G GK++LL L VP
Sbjct: 481 IRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS 540
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDL 199
+ +++ T A + + + V+ L + ++ + ++ ++ +
Sbjct: 541 VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL-----------TVKENLRLFAKIKGI 589
Query: 200 SADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHL 259
E ++ L + +Q ++ SGG ++ A+ P +LLLDEPT L
Sbjct: 590 LPHEVEKEVQRVVQELEM-ENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGL 648
Query: 260 D 260
D
Sbjct: 649 D 649
Score = 32.3 bits (70), Expect = 5.3
Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
Q ++VY + L A ++ L +++ K S G + ++ ++ P
Sbjct: 1381 QHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPV-KTLSEGIKRKLRFVLSILGNP 1439
Query: 248 HLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRL 303
++LLDEP+ +D + +W + ++ +R +L +H VC + M RL
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1499
Query: 304 K 304
+
Sbjct: 1500 R 1500
>AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein
protein.
Length = 1708
Score = 46.0 bits (104), Expect = 4e-04
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 145 LTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSA 201
LT P + A E+ ++ V++ K + + D+ + + + Y +L LS
Sbjct: 583 LTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR 642
Query: 202 DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
+LH +G + ++ + SGG R ++++ AL +L+LDEPT+ +D
Sbjct: 643 QKCPEEVKQMLHIIGLEDKWNSRS-RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDA 701
Query: 262 DA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+ +W + + R +VL +H D + + I M+K L+
Sbjct: 702 ISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQ 746
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 182 DDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALAR 241
D + +++ +Y RL + A N L GL + K + +SGG + +++
Sbjct: 1473 DHMTGREMLVMYARLRGIPERHIGACVENTLRGL-LLEPHANKLVRTYSGGNKRKLSTGI 1531
Query: 242 ALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLISHSQDFLNGVCTNIVHM 298
AL +P ++ LDEP+ +D A +W + + +++ SHS + +CT + M
Sbjct: 1532 ALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIM 1591
Query: 299 SKRRLK 304
+ + K
Sbjct: 1592 VQGQFK 1597
>AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane
specific ATP-binding cassette protein protein.
Length = 1704
Score = 46.0 bits (104), Expect = 4e-04
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 145 LTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCE---DDESQEQLMDVYDRLDDLSA 201
LT P + A E+ ++ V++ K + + D+ + + + Y +L LS
Sbjct: 579 LTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVAEHLYFYAQLKGLSR 638
Query: 202 DTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDL 261
+LH +G + ++ + SGG R ++++ AL +L+LDEPT+ +D
Sbjct: 639 QKCPEEVKQMLHIIGLEDKWNSRS-RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDA 697
Query: 262 DA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
+ +W + + R +VL +H D + + I M+K L+
Sbjct: 698 ISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGELQ 742
Score = 44.0 bits (99), Expect = 0.002
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 182 DDESQEQLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALAR 241
D + +++ +Y RL + A N L GL + K + +SGG + +++
Sbjct: 1469 DHMTGREMLVMYARLRGIPERHIGACVENTLRGL-LLEPHANKLVRTYSGGNKRKLSTGI 1527
Query: 242 ALYVKPHLLLLDEPTNHLDLDA--CVW-LEEELKHYKRILVLISHSQDFLNGVCTNIVHM 298
AL +P ++ LDEP+ +D A +W + + +++ SHS + +CT + M
Sbjct: 1528 ALIGEPAVIFLDEPSTGMDPVARRLLWDTVARARESGKAIIITSHSMEECEALCTRLAIM 1587
Query: 299 SKRRLK 304
+ + K
Sbjct: 1588 VQGQFK 1593
>BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.
Length = 1621
Score = 45.6 bits (103), Expect = 5e-04
Identities = 55/211 (26%), Positives = 90/211 (42%), Gaps = 17/211 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG-MIRKNSH----LRIGRYXXX 468
+N+ F + L L+G NGAGKST +K++ GD P+ G ++ K S L Y
Sbjct: 1307 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQ 1366
Query: 469 XXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRY--GLTGRQQV-CPMRQLSDGQRCRV 525
+ + + + I R L + Q+ P++ LS+G + ++
Sbjct: 1367 ENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKL 1426
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAI----NDFDGGMVLVSHDFRLINQVAN 581
F P ++LLDEP+ +D E + AI + + G +L +H V +
Sbjct: 1427 CFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCD 1486
Query: 582 EIWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLKSK KD
Sbjct: 1487 RVAIMVSG-RLRCIGSI----QHLKSKFGKD 1512
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 30/233 (12%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + + G E L+D + ++ G+ ++G +G GKS+LL L VP
Sbjct: 480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS 539
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDV------Y 193
+ I++ +K + E LE L+++ C Q + V +
Sbjct: 540 VTIYN--------NKLS---------EMADLENLSKLTGVCPQSNVQFDFLTVRENLRLF 582
Query: 194 DRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLD 253
++ + + +L L K +Q ++ SGG + ++ A+ P + LLD
Sbjct: 583 AKIKGILPQEVDKEIQRVLLELEM-KNIQDVLAQNLSGGQKRKLTFGIAILGDPQIFLLD 641
Query: 254 EPTNHLDLDA--CVWLEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRLK 304
EPT LD + VW + + R+++ + D + + V +S+ +LK
Sbjct: 642 EPTAGLDPFSRHQVWNLLKERKTDRVILFSTQFMDEADILADRKVFLSQGKLK 694
Score = 41.9 bits (94), Expect = 0.007
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 20/171 (11%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV+ Y I K+L F I A++G +GAGKSTLL +L G VP+ G
Sbjct: 480 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS 539
Query: 454 IRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRER----------------EEMR 497
+ ++ ++ + +F VRE +E++
Sbjct: 540 VTIYNN-KLSEMADLENLSKLTGVCPQSNVQFDFLTVRENLRLFAKIKGILPQEVDKEIQ 598
Query: 498 KIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+++ + Q V + LS GQ+ ++ F P + LLDEPT LD
Sbjct: 599 RVLLELEMKNIQDVL-AQNLSGGQKRKLTFGIAILGDPQIFLLDEPTAGLD 648
Score = 36.3 bits (80), Expect = 0.32
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
Q ++VY + L AE ++ L +++ K S G + ++ ++ P
Sbjct: 1378 QHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPV-KTLSEGIKRKLCFVLSILGNP 1436
Query: 248 HLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRL 303
++LLDEP+ +D + +W + ++ +R +L +H VC + M RL
Sbjct: 1437 SVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1496
Query: 304 K 304
+
Sbjct: 1497 R 1497
>BC064384-1|AAH64384.1| 769|Homo sapiens ABCB9 protein protein.
Length = 769
Score = 45.6 bits (103), Expect = 5e-04
Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 14/195 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 493 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 553 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 603
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 604 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 662
Query: 249 LLLLDEPTNHLDLDA 263
+L+LDE T+ LD ++
Sbjct: 663 VLILDEATSALDAES 677
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 507 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Score = 33.5 bits (73), Expect = 2.3
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ RV A + P +L+LDE T+ LD E+
Sbjct: 642 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAES 677
>AB112583-1|BAC98410.1| 681|Homo sapiens TAP-Like isoform 12C
protein.
Length = 681
Score = 45.6 bits (103), Expect = 5e-04
Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 14/195 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 493 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 553 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 603
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 604 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 662
Query: 249 LLLLDEPTNHLDLDA 263
+L+LDE T+ LD ++
Sbjct: 663 VLILDEATSALDAES 677
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 507 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Score = 33.5 bits (73), Expect = 2.3
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ RV A + P +L+LDE T+ LD E+
Sbjct: 642 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAES 677
>AB112582-1|BAC98409.1| 683|Homo sapiens TAP-Like isoform 12B
protein.
Length = 683
Score = 45.6 bits (103), Expect = 5e-04
Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 14/195 (7%)
Query: 73 GSLAVHPRSRDIKIANFSITFYG---SELLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL 129
GSLA + N + T+ +++LQ+ L+ G+ LVG +G GKSS + L
Sbjct: 493 GSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Query: 130 GRREVPIPEHIDIFHLTREMPASDKTALQCVME-VDEERVKLEKLAEMLAHCEDDESQEQ 188
P+ E + + + A D L V+ V +E V + A D
Sbjct: 553 -ENFYPL-EGGRVLLDGKPISAYDHKYLHRVISLVSQEPV-------LFARSITDNISYG 603
Query: 189 LMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPH 248
L V + +A A A + G++ E +K + SGG + R+A+ARAL P
Sbjct: 604 LPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQ-LSGGQKQRVAMARALVRNPP 662
Query: 249 LLLLDEPTNHLDLDA 263
+L+LDE T+ LD ++
Sbjct: 663 VLILDEATSALDAES 677
Score = 34.3 bits (75), Expect = 1.3
Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 399 QNVSFRY-TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLL 443
+NV+F Y T + +N+ F + ALVGP+G+GKS+ + +L
Sbjct: 507 ENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNIL 552
Score = 33.5 bits (73), Expect = 2.3
Identities = 17/36 (47%), Positives = 23/36 (63%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMET 551
QLS GQ+ RV A + P +L+LDE T+ LD E+
Sbjct: 642 QLSGGQKQRVAMARALVRNPPVLILDEATSALDAES 677
>AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.
Length = 1591
Score = 45.6 bits (103), Expect = 5e-04
Identities = 55/211 (26%), Positives = 90/211 (42%), Gaps = 17/211 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG-MIRKNSH----LRIGRYXXX 468
+N+ F + L L+G NGAGKST +K++ GD P+ G ++ K S L Y
Sbjct: 1277 RNVSFCVRKGEVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQ 1336
Query: 469 XXXXXXXXXXXXXYMMKEFPEVREREEMRKIIGRY--GLTGRQQV-CPMRQLSDGQRCRV 525
+ + + + I R L + Q+ P++ LS+G + ++
Sbjct: 1337 ENALWPNLTVRQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKL 1396
Query: 526 VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAI----NDFDGGMVLVSHDFRLINQVAN 581
F P ++LLDEP+ +D E + AI + + G +L +H V +
Sbjct: 1397 CFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCD 1456
Query: 582 EIWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLKSK KD
Sbjct: 1457 RVAIMVSG-RLRCIGSI----QHLKSKFGKD 1482
Score = 37.1 bits (82), Expect = 0.19
Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 396 IMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGM 453
I ++NV+ Y I K+L F I A++G +GAGKSTLL +L G VP+ G
Sbjct: 490 IRIRNVTKEYKGKPDKIEALKDLVFDIYEGQITAILGHSGAGKSTLLNILSGLSVPTKGS 549
Query: 454 I 454
+
Sbjct: 550 V 550
Score = 36.3 bits (80), Expect = 0.32
Identities = 26/121 (21%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Query: 188 QLMDVYDRLDDLSADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKP 247
Q ++VY + L AE ++ L +++ K S G + ++ ++ P
Sbjct: 1348 QHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPV-KTLSEGIKRKLCFVLSILGNP 1406
Query: 248 HLLLLDEPTNHLDLDA--CVW--LEEELKHYKRILVLISHSQDFLNGVCTNIVHMSKRRL 303
++LLDEP+ +D + +W + ++ +R +L +H VC + M RL
Sbjct: 1407 SVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAIMVSGRL 1466
Query: 304 K 304
+
Sbjct: 1467 R 1467
>AB209084-1|BAD92321.1| 1011|Homo sapiens Sulfonylurea receptor 1
variant protein.
Length = 1011
Score = 45.2 bits (102), Expect = 7e-04
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 832 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 891
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQIAHMKNYI 342
H +L I+ M ++ G + F R+ +L E+ N + ++ +
Sbjct: 892 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMNRQDQELEKRRQLR 949
Query: 343 AR 344
AR
Sbjct: 950 AR 951
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 833 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 892
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 893 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 921
>X91249-1|CAA62631.1| 674|Homo sapiens white protein.
Length = 674
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein.
Length = 638
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 60 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 119
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 120 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 165
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 166 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 212
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 36 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 95
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 96 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 155
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 156 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 208
>BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 1 protein.
Length = 666
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 100 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 159
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 160 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 205
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 206 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 252
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 76 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 135
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 136 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 195
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 196 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 248
>AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette
transporter G1 protein.
Length = 785
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 207 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 266
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 267 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 312
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 313 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 359
Score = 39.9 bits (89), Expect = 0.026
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 12/135 (8%)
Query: 426 LALVGPNGAGKSTLLKLLYG-------DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXX 477
+A++GP+GAGKSTL+ +L G V G+ R ++ Y
Sbjct: 221 VAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLT 280
Query: 478 XXXXYMMKEFPEVREREEMRKIIGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQ 533
M+ +++E++E R+ + + LT G R LS GQR R+ A
Sbjct: 281 VQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVN 340
Query: 534 TPHLLLLDEPTNHLD 548
P ++ DEPT+ LD
Sbjct: 341 NPPVMFFDEPTSGLD 355
>AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog
(ATP-binding cassette transporter 8) protein.
Length = 674
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens
cDNA FLJ39977 fis, clone SPLEN2029295, moderately
similar to ATP-binding cassette, sub-family A member 8.
).
Length = 815
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 414 KNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKN------SHLRIGRYXX 467
+N+ F + L L+GP+GAGKS+ ++++ G P+ G + HL
Sbjct: 502 RNISFCVQEGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQEN 561
Query: 468 XXXXXXXXXXXXXXY-MMKEFPEVREREEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVV 526
Y +K + R + +++ + L + V P+++L+ G ++
Sbjct: 562 VLWPMLTLREHLEVYAAVKGLRKADARLAIARLVSAFKLHEQLNV-PVQKLTAGITRKLC 620
Query: 527 FAWLAWQTPHLLLLDEPTNHLD----METIDALADAINDFDGGMVLVSHDFRLINQVANE 582
F +LLLDEP+ +D + A+ + + + G++L +H+ + +
Sbjct: 621 FVLSLLGNSPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDR 680
Query: 583 IWICENGTTTKWEGGILKYKDHLKSKILKD 612
+ I +G + G I HLK+K+ KD
Sbjct: 681 VAIMVSG-RLRCIGSI----QHLKNKLGKD 705
>AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette
transporter, sub-family G member 1 protein.
Length = 674
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 111 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 170
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 171 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 216
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 217 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 263
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 87 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 146
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 147 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 206
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 207 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 259
>AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 97 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 156
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 157 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 202
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 203 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 249
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 73 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 132
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 133 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 192
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 193 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 245
>AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 78 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 137
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 138 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 183
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 184 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 230
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 54 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 113
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 114 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 173
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 174 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 226
>AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 102 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 161
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 162 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 207
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 208 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 254
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 78 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 137
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 138 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 197
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 198 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 250
>AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 78 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 137
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 138 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 183
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 184 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 230
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 54 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 113
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 114 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 173
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 174 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 226
>AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 111 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 170
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 171 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 216
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 217 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 263
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 87 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 146
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 147 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 206
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 207 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 259
>AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 97 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 156
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 157 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 202
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 203 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 249
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 73 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 132
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 133 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 192
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 193 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 245
>AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 102 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 161
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 162 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 207
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 208 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 254
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 78 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 137
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 138 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 197
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 198 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 250
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 44.8 bits (101), Expect = 0.001
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKT 155
++L D + + G LVG +G GKS+ L + R P + + H R + + +
Sbjct: 436 KILNDLNMAIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSL--NIQW 493
Query: 156 ALQCVMEVDEERVKLEK-LAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
+ V++E V +AE + + +D + E ++ EA A N +
Sbjct: 494 LRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQA----------AKEANAYNFIMD 543
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
L + + + SGG + R+A+ARAL P +LLLD T+ LD ++ ++E L
Sbjct: 544 LPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK 603
Query: 274 YKRILVLIS 282
+ +IS
Sbjct: 604 IQHGHTIIS 612
Score = 40.7 bits (91), Expect = 0.015
Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 396 IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
I NV+F Y I +L I ALVGP+GAGKST L+L+ P GM+
Sbjct: 420 IEFHNVTFHYPSRPEVKILNDLNMAIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMV 479
Query: 455 RKNSH 459
+ H
Sbjct: 480 TVDGH 484
Score = 37.9 bits (84), Expect = 0.11
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
Q+S GQ+ RV A + P +LLLD T+ LD E+ + + ++ G ++S RL
Sbjct: 558 QMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRL 617
Query: 576 IN-QVANEIWICENGTTTK 593
+ A+ I E+GT +
Sbjct: 618 STVRAADTIIGFEHGTAVE 636
Score = 35.9 bits (79), Expect = 0.43
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
S G + RIA+ARA+ P +LLLDE T+ LD ++ ++ L + R ++I+H
Sbjct: 1220 SRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAH 1275
Score = 33.5 bits (73), Expect = 2.3
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS G++ R+ A + P +LLLDE T+ LD E+ + A++ G ++++H
Sbjct: 1218 QLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRL 1277
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + G
Sbjct: 1278 STI-QNADIIAVMAQG 1292
>AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein.
Length = 2413
Score = 44.8 bits (101), Expect = 0.001
Identities = 19/40 (47%), Positives = 27/40 (67%)
Query: 415 NLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
N+ GI L+G NGAGK+T+ K+L GD++PS+G I
Sbjct: 2275 NISIGIPAGECFGLLGVNGAGKTTIFKMLTGDIIPSSGNI 2314
Score = 31.5 bits (68), Expect = 9.2
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 427 ALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
+L+GPNGAGK+T + +L G S G I
Sbjct: 1375 SLLGPNGAGKTTTISMLTGLFGASAGTI 1402
>AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein.
Length = 674
Score = 44.8 bits (101), Expect = 0.001
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTA 156
LL+ + N G ++G +G GKS+L+ L G RE + + I L R++ K +
Sbjct: 96 LLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVS 155
Query: 157 LQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGLG 216
C + D+ +L H E+ ++ + +L + E IL LG
Sbjct: 156 --CYIMQDDM---------LLPHLTVQEAM--MVSAHLKLQEKDEGRREM-VKEILTALG 201
Query: 217 FTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC 264
+ T SGG R R+A+A L P ++ DEPT+ LD +C
Sbjct: 202 LLSCANTR-TGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC 248
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 24/173 (13%)
Query: 400 NVSFR---YT-DSGPWI----YKNLEFGI----DLDTRLALVGPNGAGKSTLLKLLYG-- 445
N+ FR Y+ GPW YK L GI + +A++GP+GAGKSTL+ +L G
Sbjct: 72 NIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYR 131
Query: 446 -----DLVPSTGMIRK-NSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVREREEMRKI 499
V G+ R ++ Y M+ +++E++E R+
Sbjct: 132 ETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRRE 191
Query: 500 IGRYGLT--GRQQVCPMR--QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+ + LT G R LS GQR R+ A P ++ DEPT+ LD
Sbjct: 192 MVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLD 244
>U63455-1|AAB36700.1| 1581|Homo sapiens sulfonylurea receptor
protein.
Length = 1581
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 828 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 887
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 888 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 936
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 829 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 888
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 889 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 917
>U63421-1|AAB36699.1| 1581|Homo sapiens sulfonylurea receptor
protein.
Length = 1581
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 828 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 887
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 888 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 936
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 829 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 888
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 889 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 917
>L78243-2|AAB02418.1| 1582|Homo sapiens SUR1 protein.
Length = 1582
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 829 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 888
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 889 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 937
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 830 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 889
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 890 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 918
>L78243-1|AAB02417.1| 1581|Homo sapiens SUR1 protein.
Length = 1581
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 828 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 887
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 888 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 936
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 829 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 888
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 889 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 917
>L78207-1|AAB02278.1| 1581|Homo sapiens sulfonylurea receptor
protein.
Length = 1581
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 828 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 887
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 888 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 936
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 829 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 888
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 889 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 917
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKT 155
++L D + + G LVG +G GKS+ L + R P + + H R + + +
Sbjct: 436 KILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSL--NIQW 493
Query: 156 ALQCVMEVDEERVKLEK-LAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
+ V++E V +AE + + +D + E ++ EA A N +
Sbjct: 494 LRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQA----------AKEANAYNFIMD 543
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
L + + + SGG + R+A+ARAL P +LLLD T+ LD ++ ++E L
Sbjct: 544 LPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK 603
Query: 274 YKRILVLIS 282
+ +IS
Sbjct: 604 IQHGHTIIS 612
Score = 39.5 bits (88), Expect = 0.035
Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 396 IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
I NV+F Y I +L I ALVGP+GAGKST L+L+ P GM+
Sbjct: 420 IEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMV 479
Query: 455 RKNSH 459
+ H
Sbjct: 480 TVDGH 484
Score = 37.9 bits (84), Expect = 0.11
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
Q+S GQ+ RV A + P +LLLD T+ LD E+ + + ++ G ++S RL
Sbjct: 558 QMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRL 617
Query: 576 IN-QVANEIWICENGTTTK 593
+ A+ I E+GT +
Sbjct: 618 STVRAADTIIGFEHGTAVE 636
Score = 35.9 bits (79), Expect = 0.43
Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK--RILVLISH 283
S G + RIA+ARA+ P +LLLDE T+ LD ++ ++ L + R ++I+H
Sbjct: 1220 SRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAH 1275
Score = 33.5 bits (73), Expect = 2.3
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVSHDF 573
QLS G++ R+ A + P +LLLDE T+ LD E+ + A++ G ++++H
Sbjct: 1218 QLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRL 1277
Query: 574 RLINQVANEIWICENG 589
I Q A+ I + G
Sbjct: 1278 STI-QNADIIAVMAQG 1292
>AF087138-1|AAC36724.1| 1581|Homo sapiens sulfonylurea receptor 1
protein.
Length = 1581
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 228 DFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDAC-----VWLEEELKHYKRILVLIS 282
+ SGG R RI++ARALY +++ LD+P + LD+ + E L+ KR +VL++
Sbjct: 828 NLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVT 887
Query: 283 HSQDFLNGVCTNIVHMSKRRLKYYTGNYEAFVRTRMELLENQMKQYNWEQDQ 334
H +L I+ M ++ G + F R+ +L E+ N QDQ
Sbjct: 888 HKLQYLPH-ADWIIAMKDGTIQ-REGTLKDFQRSECQLFEHWKTLMN-RQDQ 936
Score = 33.1 bits (72), Expect = 3.0
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 517 LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADA-----INDFDGGMVLVSH 571
LS GQR R+ A +Q +++ LD+P + LD+ D L A + D +VLV+H
Sbjct: 829 LSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTH 888
Query: 572 DFRLINQVANEIWICENGTTTKWEGGILKYK 602
+ + A+ I ++GT + EG + ++
Sbjct: 889 KLQYLPH-ADWIIAMKDGTIQR-EGTLKDFQ 917
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 97 ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIF-HLTREMPASDKT 155
++L D + + G LVG +G GKS+ L + R P + + H R + + +
Sbjct: 436 KILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSL--NIQW 493
Query: 156 ALQCVMEVDEERVKLEK-LAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
+ V++E V +AE + + +D + E ++ EA A N +
Sbjct: 494 LRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQA----------AKEANAYNFIMD 543
Query: 215 LGFTKE-MQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKH 273
L + + + SGG + R+A+ARAL P +LLLD T+ LD ++ ++E L
Sbjct: 544 LPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK 603
Query: 274 YKRILVLIS 282
+ +IS
Sbjct: 604 IQHGHTIIS 612
Score = 39.5 bits (88), Expect = 0.035
Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 396 IMVQNVSFRYTDSGPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
I NV+F Y I +L I ALVGP+GAGKST L+L+ P GM+
Sbjct: 420 IEFHNVTFHYPSRPEVKILNDLNMVIKPGEMTALVGPSGAGKSTALQLIQRFYDPCEGMV 479
Query: 455 RKNSH 459
+ H
Sbjct: 480 TVDGH 484
Score = 37.9 bits (84), Expect = 0.11
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
Q+S GQ+ RV A + P +LLLD T+ LD E+ + + ++ G ++S RL
Sbjct: 558 QMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRL 617
Query: 576 IN-QVANEIWICENGTTTK 593
+ A+ I E+GT +
Sbjct: 618 STVRAADTIIGFEHGTAVE 636
>Z31348-1|CAA83230.1| 745|Homo sapiens adrenoleukodystropy protein.
Length = 745
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--- 452
I+ +N+ T SG + +L ++ L + GPNG GKS+L ++L G L P+ G
Sbjct: 474 IICENIPI-VTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRIL-GGLWPTYGGVL 531
Query: 453 ---------MIRKNSHLRIGRYXXXXXX-XXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
I + ++ +G Y ++ + + + I+ R
Sbjct: 532 YKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQR 591
Query: 503 YGLTGRQQVCPMRQ-LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND 561
G G + +C + LS G++ R+ A + + P LLDE T+ + ++ + A D
Sbjct: 592 EG--GWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKD 649
Query: 562 FDGGMVLVSH 571
++ ++H
Sbjct: 650 AGIALLSITH 659
Score = 33.9 bits (74), Expect = 1.7
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISH 283
SGG + RI +AR Y +P LLDE T+ + +D + + K L+ I+H
Sbjct: 606 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITH 659
>Z21876-1|CAA79922.1| 745|Homo sapiens ALD protein (ALDP) protein.
Length = 745
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--- 452
I+ +N+ T SG + +L ++ L + GPNG GKS+L ++L G L P+ G
Sbjct: 474 IICENIPI-VTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRIL-GGLWPTYGGVL 531
Query: 453 ---------MIRKNSHLRIGRYXXXXXX-XXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
I + ++ +G Y ++ + + + I+ R
Sbjct: 532 YKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQR 591
Query: 503 YGLTGRQQVCPMRQ-LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND 561
G G + +C + LS G++ R+ A + + P LLDE T+ + ++ + A D
Sbjct: 592 EG--GWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKD 649
Query: 562 FDGGMVLVSH 571
++ ++H
Sbjct: 650 AGIALLSITH 659
Score = 33.9 bits (74), Expect = 1.7
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISH 283
SGG + RI +AR Y +P LLDE T+ + +D + + K L+ I+H
Sbjct: 606 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITH 659
>X58528-1|CAA41416.1| 659|Homo sapiens 70kDa peroxisomal membrane
protein protein.
Length = 659
Score = 44.0 bits (99), Expect = 0.002
Identities = 49/189 (25%), Positives = 80/189 (42%), Gaps = 15/189 (7%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G L++D E+ G + G NGCGKSSL LG E +F P ++
Sbjct: 452 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLG-------ELWPLFGGRLTKP--ER 502
Query: 155 TALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L V + + L L + + + + E Q++ + D + D + +IL
Sbjct: 503 RKLFYVPQ--RPYMTLGTLRDQVIYPDGREDQKR-KGISDLVQKEYLDNVQL--GHILER 557
Query: 215 LGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHY 274
G +Q SGG + R+A+AR Y KP +LDE T+ + +D ++ +
Sbjct: 558 EGGWDSVQDWMDV-LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKV 616
Query: 275 KRILVLISH 283
L +SH
Sbjct: 617 GITLFTVSH 625
Score = 35.1 bits (77), Expect = 0.75
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 406 TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
T +G + ++L F + + + GPNG GKS+L ++L G+L P G
Sbjct: 449 TPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVL-GELWPLFG 494
>BC025358-1|AAH25358.1| 745|Homo sapiens ATP-binding cassette,
sub-family D (ALD), member 1 protein.
Length = 745
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--- 452
I+ +N+ T SG + +L ++ L + GPNG GKS+L ++L G L P+ G
Sbjct: 474 IICENIPI-VTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRIL-GGLWPTYGGVL 531
Query: 453 ---------MIRKNSHLRIGRYXXXXXX-XXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
I + ++ +G Y ++ + + + I+ R
Sbjct: 532 YKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQR 591
Query: 503 YGLTGRQQVCPMRQ-LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND 561
G G + +C + LS G++ R+ A + + P LLDE T+ + ++ + A D
Sbjct: 592 EG--GWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKD 649
Query: 562 FDGGMVLVSH 571
++ ++H
Sbjct: 650 AGIALLSITH 659
Score = 33.9 bits (74), Expect = 1.7
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISH 283
SGG + RI +AR Y +P LLDE T+ + +D + + K L+ I+H
Sbjct: 606 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITH 659
>BC015541-1|AAH15541.1| 745|Homo sapiens ATP-binding cassette,
sub-family D (ALD), member 1 protein.
Length = 745
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 18/190 (9%)
Query: 396 IMVQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG--- 452
I+ +N+ T SG + +L ++ L + GPNG GKS+L ++L G L P+ G
Sbjct: 474 IICENIPI-VTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRIL-GGLWPTYGGVL 531
Query: 453 ---------MIRKNSHLRIGRYXXXXXX-XXXXXXXXXXYMMKEFPEVREREEMRKIIGR 502
I + ++ +G Y ++ + + + I+ R
Sbjct: 532 YKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQR 591
Query: 503 YGLTGRQQVCPMRQ-LSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAIND 561
G G + +C + LS G++ R+ A + + P LLDE T+ + ++ + A D
Sbjct: 592 EG--GWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKD 649
Query: 562 FDGGMVLVSH 571
++ ++H
Sbjct: 650 AGIALLSITH 659
Score = 33.9 bits (74), Expect = 1.7
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKRILVLISH 283
SGG + RI +AR Y +P LLDE T+ + +D + + K L+ I+H
Sbjct: 606 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITH 659
>AK223300-1|BAD97020.1| 703|Homo sapiens transporter 2, ATP-binding
cassette, sub-family B isoform 1 variant protein.
Length = 703
Score = 44.0 bits (99), Expect = 0.002
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLNQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRAVLVIAH 661
Score = 42.7 bits (96), Expect = 0.004
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRAVLVIAHRLQA 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
Score = 41.5 bits (93), Expect = 0.009
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLNQPTGGQV 527
>AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ33951 fis, clone CTONG2018483, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 293
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 224 KATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYKR---ILVL 280
K +SGG + +++ A AL KP +LLLDEP++ +D + +L + + R VL
Sbjct: 87 KPVATYSGGTKRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKEVREGCAAVL 146
Query: 281 ISHSQDFLNGVCTNIVHM 298
SHS + +CT + M
Sbjct: 147 TSHSMEECEALCTRLAIM 164
>Z22935-1|CAA80522.1| 703|Homo sapiens TAP2B protein.
Length = 703
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>X87344-8|CAA60788.1| 686|Homo sapiens TAP2 protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>X66401-4|CAA47027.1| 686|Homo sapiens TAP2 protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>U18236-1|AAA84437.2| 131|Homo sapiens ATP-binding cassette protein
protein.
Length = 131
Score = 43.2 bits (97), Expect = 0.003
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 212 LHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDA--CVW-LE 268
L L TK K +SGG + +++ A AL P + LDEPT +D A +W L
Sbjct: 6 LEKLELTK-YADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLI 64
Query: 269 EELKHYKRILVLISHSQDFLNGVCTNIVHMSKR 301
+L R +VL SHS + +CT + M +R
Sbjct: 65 LDLIKTGRSVVLTSHSMEECEALCTRLAIMGER 97
>M74447-1|AAA59841.1| 703|Homo sapiens PSF-2 protein.
Length = 703
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>BX682530-4|CAI41935.1| 703|Homo sapiens transporter 2 ATP-binding
cassette sub-family B (MDR/TAP) protein.
Length = 703
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>BT009906-1|AAP88908.1| 686|Homo sapiens transporter 2, ATP-binding
cassette, sub-family B (MDR/TAP) protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 8 (sterolin 2) protein.
Length = 673
Score = 43.2 bits (97), Expect = 0.003
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 15/167 (8%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTAL 157
+Q+ ++ G+ ++G +GCG++SLL + GR + I+ P+S +
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIW--INGQPSSPQLVR 145
Query: 158 QCVMEVDEERVKLEKLA--EMLAHCEDDESQEQLMDVY--DRLDDLSADTAEARAANILH 213
+CV V + L L E LA R++D+ A+ + A+
Sbjct: 146 KCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRV 205
Query: 214 GLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G + + + SGG R R+++ L P +L+LDEPT+ LD
Sbjct: 206 GNMYVRGL--------SGGERRRVSIGVQLLWNPGILILDEPTSGLD 244
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 514 MRQLSDGQRCRV-VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVS 570
+R LS G+R RV + L W P +L+LDEPT+ LD T L ++ G +VL+S
Sbjct: 210 VRGLSGGERRRVSIGVQLLWN-PGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLIS 268
>AL935043-2|CAI18622.1| 686|Homo sapiens transporter 2, ATP-binding
cassette, sub-family Bta protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>AL671681-8|CAI17711.1| 686|Homo sapiens transporter 2, ATP-binding
cassette, sub-family Bta 9 (pseudogene) protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>AL669918-4|CAI18137.1| 686|Homo sapiens transporter 2, ATP-binding
cassette, sub-family Bunit 11 protein.
Length = 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>AK222823-1|BAD96543.1| 703|Homo sapiens transporter 2, ATP-binding
cassette, sub-family B isoform 1 variant protein.
Length = 703
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 540
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 541 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 591
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 592 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 647
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 648 WNSRGDRTVLVIAH 661
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein.
Length = 672
Score = 43.2 bits (97), Expect = 0.003
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 15/167 (8%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTAL 157
+Q+ ++ G+ ++G +GCG++SLL + GR + I+ P+S +
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIW--INGQPSSPQLVR 145
Query: 158 QCVMEVDEERVKLEKLA--EMLAHCEDDESQEQLMDVY--DRLDDLSADTAEARAANILH 213
+CV V + L L E LA R++D+ A+ + A+
Sbjct: 146 KCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRV 205
Query: 214 GLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G + + + SGG R R+++ L P +L+LDEPT+ LD
Sbjct: 206 GNMYVRGL--------SGGERRRVSIGVQLLWNPGILILDEPTSGLD 244
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 514 MRQLSDGQRCRV-VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVS 570
+R LS G+R RV + L W P +L+LDEPT+ LD T L ++ G +VL+S
Sbjct: 210 VRGLSGGERRRVSIGVQLLWN-PGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLIS 268
>AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein.
Length = 673
Score = 43.2 bits (97), Expect = 0.003
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 15/167 (8%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTAL 157
+Q+ ++ G+ ++G +GCG++SLL + GR + I+ P+S +
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIW--INGQPSSPQLVR 145
Query: 158 QCVMEVDEERVKLEKLA--EMLAHCEDDESQEQLMDVY--DRLDDLSADTAEARAANILH 213
+CV V + L L E LA R++D+ A+ + A+
Sbjct: 146 KCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRV 205
Query: 214 GLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G + + + SGG R R+++ L P +L+LDEPT+ LD
Sbjct: 206 GNMYVRGL--------SGGERRRVSIGVQLLWNPGILILDEPTSGLD 244
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 514 MRQLSDGQRCRV-VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVS 570
+R LS G+R RV + L W P +L+LDEPT+ LD T L ++ G +VL+S
Sbjct: 210 VRGLSGGERRRVSIGVQLLWN-PGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLIS 268
>AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein.
Length = 673
Score = 43.2 bits (97), Expect = 0.003
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 15/167 (8%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTAL 157
+Q+ ++ G+ ++G +GCG++SLL + GR + I+ P+S +
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIW--INGQPSSPQLVR 145
Query: 158 QCVMEVDEERVKLEKLA--EMLAHCEDDESQEQLMDVY--DRLDDLSADTAEARAANILH 213
+CV V + L L E LA R++D+ A+ + A+
Sbjct: 146 KCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRV 205
Query: 214 GLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G + + + SGG R R+++ L P +L+LDEPT+ LD
Sbjct: 206 GNMYVRGL--------SGGERRRVSIGVQLLWNPGILILDEPTSGLD 244
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 514 MRQLSDGQRCRV-VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVS 570
+R LS G+R RV + L W P +L+LDEPT+ LD T L ++ G +VL+S
Sbjct: 210 VRGLSGGERRRVSIGVQLLWN-PGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLIS 268
>AF176984-1|AAD50509.1| 372|Homo sapiens TAP2 protein protein.
Length = 372
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 170 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 225
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 226 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 276
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 277 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 332
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 333 WNSRGDRTVLVIAH 346
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 123 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 182
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 183 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 212
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 291 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 350
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 351 V-QRAHQILVLQEGKLQK 367
>AF136750-1|AAD23601.1| 483|Homo sapiens TAP2 protein protein.
Length = 483
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 282 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 337
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 338 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 388
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 389 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 444
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 445 WNSRGDRTVLVIAH 458
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P ++ Q+VSF Y + + K L F +
Sbjct: 235 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGIVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 294
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 295 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 324
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 403 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 462
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 463 V-QRAHQILVLQEGKLQK 479
>AF100418-1|AAD23381.1| 483|Homo sapiens TAP2 protein protein.
Length = 483
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 282 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 337
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 338 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 388
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 389 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 444
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 445 WNSRGDRTVLVIAH 458
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P ++ Q+VSF Y + + K L F +
Sbjct: 235 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGIVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 294
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 295 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 324
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 403 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 462
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 463 V-QRAHQILVLQEGKLQK 479
>AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein.
Length = 673
Score = 43.2 bits (97), Expect = 0.003
Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 15/167 (8%)
Query: 99 LQDTLLELNCGRRYGLVGLNGCGKSSLLAAL-GRREVPIPEHIDIFHLTREMPASDKTAL 157
+Q+ ++ G+ ++G +GCG++SLL + GR + I+ P+S +
Sbjct: 88 IQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIW--INGQPSSPQLVR 145
Query: 158 QCVMEVDEERVKLEKLA--EMLAHCEDDESQEQLMDVY--DRLDDLSADTAEARAANILH 213
+CV V + L L E LA R++D+ A+ + A+
Sbjct: 146 KCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRV 205
Query: 214 GLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
G + + + SGG R R+++ L P +L+LDEPT+ LD
Sbjct: 206 GNMYVRGL--------SGGERRRVSIGVQLLWNPGILILDEPTSGLD 244
Score = 34.7 bits (76), Expect = 0.99
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 4/60 (6%)
Query: 514 MRQLSDGQRCRV-VFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGG--MVLVS 570
+R LS G+R RV + L W P +L+LDEPT+ LD T L ++ G +VL+S
Sbjct: 210 VRGLSGGERRRVSIGVQLLWN-PGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLIS 268
>AB208953-1|BAD92190.1| 704|Homo sapiens transporter 2, ATP-binding
cassette, sub-family B isoform 1 variant protein.
Length = 704
Score = 43.2 bits (97), Expect = 0.003
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 486 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 541
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 542 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 592
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 593 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 648
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 649 WNSRGDRTVLVIAH 662
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 439 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 498
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 499 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 528
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 607 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQA 666
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 667 V-QRAHQILVLQEGKLQK 683
>M81182-1|AAA60128.1| 659|Homo sapiens 70kDa peroxisomal membrane
protein protein.
Length = 659
Score = 42.7 bits (96), Expect = 0.004
Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 15/189 (7%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G L++D E+ G + G NGCGKSSL LG E +F P K
Sbjct: 452 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLG-------ELWPLFGGRLTKPERGK 504
Query: 155 TALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L V + + L L + + + + E Q++ + D + L + +IL
Sbjct: 505 --LFYVPQ--RPYMTLGTLRDQVIYPDGREDQKR-KGISDLV--LKEYLDNVQLGHILER 557
Query: 215 LGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHY 274
G +Q SGG + R+A+AR Y KP +LDE T+ + +D ++ +
Sbjct: 558 EGGWDSVQDWMDV-LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKV 616
Query: 275 KRILVLISH 283
L +SH
Sbjct: 617 GITLFTVSH 625
Score = 35.1 bits (77), Expect = 0.75
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 406 TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
T +G + ++L F + + + GPNG GKS+L ++L G+L P G
Sbjct: 449 TPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVL-GELWPLFG 494
>BC068509-1|AAH68509.1| 549|Homo sapiens ABCD3 protein protein.
Length = 549
Score = 42.7 bits (96), Expect = 0.004
Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 15/189 (7%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G L++D E+ G + G NGCGKSSL LG E +F P K
Sbjct: 342 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLG-------ELWPLFGGRLTKPERGK 394
Query: 155 TALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L V + + L L + + + + E Q++ + D + L + +IL
Sbjct: 395 --LFYVPQ--RPYMTLGTLRDQVIYPDGREDQKR-KGISDLV--LKEYLDNVQLGHILER 447
Query: 215 LGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHY 274
G +Q SGG + R+A+AR Y KP +LDE T+ + +D ++ +
Sbjct: 448 EGGWDSVQDWMDV-LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKV 506
Query: 275 KRILVLISH 283
L +SH
Sbjct: 507 GITLFTVSH 515
Score = 35.1 bits (77), Expect = 0.75
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 406 TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
T +G + ++L F + + + GPNG GKS+L ++L G+L P G
Sbjct: 339 TPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVL-GELWPLFG 384
>AL138758-1|CAC15960.2| 659|Homo sapiens ATP-binding cassette,
sub-family D (ALD), member 3 protein.
Length = 659
Score = 42.7 bits (96), Expect = 0.004
Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 15/189 (7%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDK 154
G L++D E+ G + G NGCGKSSL LG E +F P K
Sbjct: 452 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLG-------ELWPLFGGRLTKPERGK 504
Query: 155 TALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHG 214
L V + + L L + + + + E Q++ + D + L + +IL
Sbjct: 505 --LFYVPQ--RPYMTLGTLRDQVIYPDGREDQKR-KGISDLV--LKEYLDNVQLGHILER 557
Query: 215 LGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHY 274
G +Q SGG + R+A+AR Y KP +LDE T+ + +D ++ +
Sbjct: 558 EGGWDSVQDWMDV-LSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKV 616
Query: 275 KRILVLISH 283
L +SH
Sbjct: 617 GITLFTVSH 625
Score = 35.1 bits (77), Expect = 0.75
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 406 TDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTG 452
T +G + ++L F + + + GPNG GKS+L ++L G+L P G
Sbjct: 449 TPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVL-GELWPLFG 494
>AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens
cDNA FLJ90010 fis, clone HEMBA1000349, weakly similar to
ATP-BINDING CASSETTE TRANSPORTER 1. ).
Length = 483
Score = 42.7 bits (96), Expect = 0.004
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 388 CGKVPPPVIMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYG 445
CGK I ++N+ Y + K + F I AL+G +GAGK+TLL +L G
Sbjct: 103 CGK---EAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSG 159
Query: 446 DLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE------------- 492
VP++G + +H + R + F V+E
Sbjct: 160 LSVPTSGSVTVYNH-TLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILP 218
Query: 493 ---REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+E+++++ + Q + + LS GQ ++ F P +LLLDEPT LD
Sbjct: 219 HEVEKEVQRVVQELEMENIQDIL-AQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLD 276
Score = 38.3 bits (85), Expect = 0.080
Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 16/181 (8%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + G E L+ + ++ G+ L+G +G GK++LL L VP
Sbjct: 108 IRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS 167
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDL 199
+ +++ T A + + + V+ L + ++ + ++ ++ +
Sbjct: 168 VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL-----------TVKENLRLFAKIKGI 216
Query: 200 SADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHL 259
E ++ L + +Q ++ SGG ++ A+ P +LLLDEPT L
Sbjct: 217 LPHEVEKEVQRVVQELEM-ENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGL 275
Query: 260 D 260
D
Sbjct: 276 D 276
>AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens
cDNA FLJ32506 fis, clone SMINT1000042, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 3. ).
Length = 856
Score = 42.7 bits (96), Expect = 0.004
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 388 CGKVPPPVIMVQNVSFRYTDSGPWI--YKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYG 445
CGK I ++N+ Y + K + F I AL+G +GAGK+TLL +L G
Sbjct: 476 CGK---EAIRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSG 532
Query: 446 DLVPSTGMIRKNSHLRIGRYXXXXXXXXXXXXXXXXYMMKEFPEVRE------------- 492
VP++G + +H + R + F V+E
Sbjct: 533 LSVPTSGSVTVYNH-TLSRMADIENISKFTGFCPQSNVQFGFLTVKENLRLFAKIKGILP 591
Query: 493 ---REEMRKIIGRYGLTGRQQVCPMRQLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLD 548
+E+++++ + Q + + LS GQ ++ F P +LLLDEPT LD
Sbjct: 592 HEVEKEVQRVVQELEMENIQDIL-AQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGLD 649
Score = 38.3 bits (85), Expect = 0.080
Identities = 38/181 (20%), Positives = 76/181 (41%), Gaps = 16/181 (8%)
Query: 84 IKIANFSITFYGS----ELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEH 139
I+I N + G E L+ + ++ G+ L+G +G GK++LL L VP
Sbjct: 481 IRIKNLKKEYAGKCERVEALKGVVFDIYEGQITALLGHSGAGKTTLLNILSGLSVPTSGS 540
Query: 140 IDIFHLTREMPASDKTALQCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDL 199
+ +++ T A + + + V+ L + ++ + ++ ++ +
Sbjct: 541 VTVYNHTLSRMADIENISKFTGFCPQSNVQFGFL-----------TVKENLRLFAKIKGI 589
Query: 200 SADTAEARAANILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHL 259
E ++ L + +Q ++ SGG ++ A+ P +LLLDEPT L
Sbjct: 590 LPHEVEKEVQRVVQELEM-ENIQDILAQNLSGGQNRKLTFGIAILGDPQVLLLDEPTAGL 648
Query: 260 D 260
D
Sbjct: 649 D 649
>Z22936-1|CAA80523.1| 686|Homo sapiens TAP2E protein.
Length = 686
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 438 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 497
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 498 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 527
Score = 41.9 bits (94), Expect = 0.007
Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 13/188 (6%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 485 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYE-- 538
Query: 158 QCVMEVDEERVKLEKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAANILHGL-- 215
C + V E + + + + L D D + A A A + + +
Sbjct: 539 HCYLHSQVVSVGQEPV--LFSGSVRNNITYGLQSCED--DKVMAAAQAAHADDFIQEMEH 594
Query: 216 GFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEEELKHYK 275
G ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 595 GIYTDVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGD 653
Query: 276 RILVLISH 283
R +++I+H
Sbjct: 654 RTVLVIAH 661
Score = 41.9 bits (94), Expect = 0.007
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 606 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQT 665
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 666 V-QRAHQILVLQEGKLQK 682
>U07844-1|AAA79901.1| 622|Homo sapiens ABC transport protein
protein.
Length = 622
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 5/90 (5%)
Query: 370 GLTEKVVDDKILNFYFPSCGKVPPP----VIMVQNVSFRYTDSGPW-IYKNLEFGIDLDT 424
G EKV PS G + P V+ Q+VSF Y + + K L F +
Sbjct: 374 GAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGE 433
Query: 425 RLALVGPNGAGKSTLLKLLYGDLVPSTGMI 454
ALVGPNG+GKST+ LL P+ G +
Sbjct: 434 VTALVGPNGSGKSTVAALLQNLYQPTGGQV 463
Score = 41.9 bits (94), Expect = 0.007
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 25/194 (12%)
Query: 98 LLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGRREVPIPEHIDIFHLTREMPASDKTAL 157
+L+ L G LVG NG GKS++ A L P + L E P S
Sbjct: 421 VLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQV----LLDEKPISQYEHC 476
Query: 158 QC---VMEVDEERVKL-----EKLAEMLAHCEDDESQEQLMDVYDRLDDLSADTAEARAA 209
V+ V +E V +A L CEDD+ + DD +
Sbjct: 477 YLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAH--ADDFIQE------- 527
Query: 210 NILHGLGFTKEMQQKATKDFSGGWRMRIALARALYVKPHLLLLDEPTNHLDLDACVWLEE 269
+ HG+ +T ++ +K ++ + G + R+A+ARAL P +L+LDE T+ LD+ L++
Sbjct: 528 -MEHGI-YT-DVGEKGSQ-LAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQD 583
Query: 270 ELKHYKRILVLISH 283
R +++I+H
Sbjct: 584 WNSCGDRTVLVIAH 597
Score = 41.5 bits (93), Expect = 0.009
Identities = 24/78 (30%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 516 QLSDGQRCRVVFAWLAWQTPHLLLLDEPTNHLDMETIDALADAINDFDGGMVLVSHDFRL 575
QL+ GQ+ R+ A + P +L+LDE T+ LD++ AL D + D +++++H +
Sbjct: 542 QLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSCGDRTVLVIAHRLQT 601
Query: 576 INQVANEIWICENGTTTK 593
+ Q A++I + + G K
Sbjct: 602 V-QRAHQILVLQEGKLQK 618
>DQ388136-1|ABD72199.1| 1321|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1321
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/52 (36%), Positives = 32/52 (61%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHL 460
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + +
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRI 488
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
>DQ356257-1|ABC87053.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/52 (36%), Positives = 32/52 (61%)
Query: 409 GPWIYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPSTGMIRKNSHL 460
G + K++ F I+ LA+ G GAGK++LL ++ G+L PS G I+ + +
Sbjct: 437 GTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRI 488
Score = 40.3 bits (90), Expect = 0.020
Identities = 18/43 (41%), Positives = 29/43 (67%)
Query: 398 VQNVSFRYTDSGPWIYKNLEFGIDLDTRLALVGPNGAGKSTLL 440
V++++ +YT+ G I +N+ F I R+ L+G G+GKSTLL
Sbjct: 1212 VKDLTAKYTEGGNAILENISFSISPGQRVGLLGRTGSGKSTLL 1254
Score = 33.5 bits (73), Expect = 2.3
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 95 GSELLQDTLLELNCGRRYGLVGLNGCGKSSLLAALGR 131
G+ +L++ ++ G+R GL+G G GKS+LL+A R
Sbjct: 1223 GNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR 1259
Score = 32.7 bits (71), Expect = 4.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 230 SGGWRMRIALARALYVKPHLLLLDEPTNHLD 260
S G + + LAR++ K +LLLDEP+ HLD
Sbjct: 1347 SHGHKQLMCLARSVLSKAKILLLDEPSAHLD 1377
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.406
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,755,485
Number of Sequences: 224733
Number of extensions: 3257629
Number of successful extensions: 10468
Number of sequences better than 10.0: 421
Number of HSP's better than 10.0 without gapping: 398
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 8218
Number of HSP's gapped (non-prelim): 2019
length of query: 622
length of database: 73,234,838
effective HSP length: 94
effective length of query: 528
effective length of database: 52,109,936
effective search space: 27514046208
effective search space used: 27514046208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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