Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001985-TA|BGIBMGA001985-PA|IPR002110|Ankyrin
(664 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC014558-1|AAH14558.1| 627|Homo sapiens fem-1 homolog b (C. ele... 530 e-150
BC010122-1|AAH10122.1| 627|Homo sapiens fem-1 homolog b (C. ele... 530 e-150
AF204883-1|AAF69303.1| 627|Homo sapiens FEM1 beta protein. 530 e-150
AF178632-1|AAF05314.1| 627|Homo sapiens FEM-1-like death recept... 530 e-150
AB007856-1|BAA23692.2| 627|Homo sapiens KIAA0396 protein. 530 e-150
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 344 5e-94
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 344 5e-94
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 344 5e-94
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 344 5e-94
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 213 1e-54
BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C. ele... 192 3e-48
AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E recepto... 192 3e-48
AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determinin... 192 3e-48
AL365409-1|CAB96953.1| 317|Homo sapiens similar to (NP_034322.1... 120 1e-26
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 116 3e-25
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 114 1e-24
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 113 1e-24
AK025265-1|BAB15096.1| 300|Homo sapiens protein ( Homo sapiens ... 111 6e-24
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 102 5e-21
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 102 5e-21
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 97 1e-19
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 97 1e-19
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 97 1e-19
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 97 1e-19
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 97 1e-19
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 97 1e-19
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 97 1e-19
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 97 2e-19
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 97 2e-19
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 96 3e-19
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 96 3e-19
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 96 3e-19
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 96 3e-19
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 96 3e-19
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 96 3e-19
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 96 3e-19
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 96 3e-19
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 96 3e-19
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 95 5e-19
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 95 5e-19
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 95 5e-19
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 95 5e-19
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 95 5e-19
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 95 5e-19
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 95 5e-19
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 95 5e-19
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 95 5e-19
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 95 5e-19
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 92 5e-18
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 92 7e-18
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 92 7e-18
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 91 9e-18
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 91 1e-17
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 91 1e-17
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 91 2e-17
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 90 2e-17
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 90 2e-17
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 90 2e-17
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 90 2e-17
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 90 2e-17
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 90 2e-17
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 90 2e-17
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 90 2e-17
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 90 2e-17
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 90 2e-17
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 90 2e-17
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 90 2e-17
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 90 2e-17
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 90 2e-17
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 90 3e-17
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 90 3e-17
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 90 3e-17
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 90 3e-17
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 90 3e-17
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 90 3e-17
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 90 3e-17
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 89 5e-17
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 89 5e-17
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 89 5e-17
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 89 5e-17
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 87 2e-16
AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 87 2e-16
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 85 8e-16
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 85 8e-16
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 85 8e-16
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 84 1e-15
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 84 1e-15
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 84 1e-15
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 84 1e-15
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 84 1e-15
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 84 1e-15
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 84 1e-15
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 84 2e-15
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 84 2e-15
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 84 2e-15
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 83 2e-15
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 83 2e-15
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 83 2e-15
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 83 2e-15
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 83 2e-15
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 83 2e-15
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 83 3e-15
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 82 5e-15
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 82 5e-15
AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens ... 82 5e-15
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 82 7e-15
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 82 7e-15
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 82 7e-15
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 81 9e-15
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 81 9e-15
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 81 9e-15
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 81 1e-14
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 81 1e-14
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 81 1e-14
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 81 1e-14
AK123496-1|BAC85629.1| 656|Homo sapiens protein ( Homo sapiens ... 81 2e-14
AB075857-1|BAB85563.1| 606|Homo sapiens KIAA1977 protein protein. 81 2e-14
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 81 2e-14
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 80 2e-14
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 80 2e-14
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 80 3e-14
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 80 3e-14
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 80 3e-14
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 80 3e-14
BC031303-1|AAH31303.1| 183|Homo sapiens ankyrin repeat domain 3... 79 4e-14
AC092636-4|AAY14966.1| 183|Homo sapiens unknown protein. 79 4e-14
AB209367-1|BAD92604.1| 192|Homo sapiens hypothetical protein MG... 79 4e-14
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 78 9e-14
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 78 9e-14
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 78 9e-14
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 78 9e-14
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 78 9e-14
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 78 9e-14
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 78 1e-13
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 78 1e-13
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 78 1e-13
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 78 1e-13
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 78 1e-13
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 78 1e-13
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 78 1e-13
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 78 1e-13
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 78 1e-13
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 77 2e-13
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 77 2e-13
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 77 2e-13
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 77 2e-13
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 77 2e-13
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 77 2e-13
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 77 2e-13
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 77 2e-13
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 77 2e-13
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 77 2e-13
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 77 2e-13
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 77 2e-13
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 77 2e-13
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 77 2e-13
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 77 2e-13
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 77 2e-13
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 77 2e-13
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 77 2e-13
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 77 3e-13
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 77 3e-13
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 77 3e-13
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 77 3e-13
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 77 3e-13
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 77 3e-13
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 77 3e-13
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 77 3e-13
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 76 4e-13
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 76 4e-13
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 76 4e-13
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 76 4e-13
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 76 4e-13
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 76 4e-13
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 76 4e-13
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 76 4e-13
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 76 4e-13
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 76 4e-13
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 76 4e-13
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 76 4e-13
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 76 4e-13
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 76 4e-13
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 76 4e-13
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 76 4e-13
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 76 4e-13
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 76 4e-13
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 76 4e-13
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 76 4e-13
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 76 4e-13
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 76 4e-13
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 76 5e-13
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 75 6e-13
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 75 8e-13
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 75 8e-13
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 75 8e-13
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 75 8e-13
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 75 8e-13
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 75 1e-12
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 75 1e-12
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 74 1e-12
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 73 4e-12
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 73 4e-12
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 73 4e-12
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 73 4e-12
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 73 4e-12
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 73 4e-12
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 72 6e-12
BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS... 72 6e-12
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 72 6e-12
AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens ... 72 6e-12
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 72 8e-12
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 72 8e-12
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 72 8e-12
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 72 8e-12
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 72 8e-12
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 72 8e-12
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 72 8e-12
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 72 8e-12
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 72 8e-12
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 72 8e-12
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 72 8e-12
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 72 8e-12
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 72 8e-12
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 72 8e-12
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 72 8e-12
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 72 8e-12
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 72 8e-12
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 72 8e-12
AK123197-1|BAC85555.1| 131|Homo sapiens protein ( Homo sapiens ... 72 8e-12
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 72 8e-12
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 72 8e-12
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 72 8e-12
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 71 1e-11
D26069-1|BAA05064.2| 781|Homo sapiens KIAA0041 protein. 71 1e-11
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 71 1e-11
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 71 1e-11
BC060767-1|AAH60767.1| 778|Homo sapiens centaurin, beta 2 protein. 71 1e-11
BC031005-1|AAH31005.1| 201|Homo sapiens Similar to centaurin, b... 71 1e-11
BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa... 71 1e-11
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 71 1e-11
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 71 1e-11
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 71 1e-11
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 71 1e-11
AJ249601-1|CAB63467.1| 559|Homo sapiens IkappaBR protein. 71 1e-11
AJ238248-1|CAB41450.1| 778|Homo sapiens centaurin beta2 protein. 71 1e-11
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 71 1e-11
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 71 1e-11
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 71 1e-11
AB209126-1|BAD92363.1| 897|Homo sapiens I-kappa-B-related prote... 71 1e-11
AL080091-1|CAB45706.2| 266|Homo sapiens hypothetical protein pr... 71 2e-11
AK098736-1|BAC05399.1| 181|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 70 3e-11
AK000904-1|BAA91417.1| 519|Homo sapiens protein ( Homo sapiens ... 70 3e-11
BC050324-1|AAH50324.1| 632|Homo sapiens zinc finger, DHHC-type ... 69 4e-11
BC030990-1|AAH30990.1| 276|Homo sapiens ZDHHC17 protein protein. 69 4e-11
BC012917-1|AAH12917.1| 313|Homo sapiens ankyrin repeat, family ... 69 4e-11
AK022876-1|BAB14288.1| 313|Homo sapiens protein ( Homo sapiens ... 69 4e-11
AF314032-1|AAK01621.1| 313|Homo sapiens ankyrin-repeat family A... 69 4e-11
AF251051-1|AAK34941.1| 313|Homo sapiens ankyrin protein. 69 4e-11
AB097035-1|BAC77388.1| 622|Homo sapiens putative MAPK activatin... 69 4e-11
AB097013-1|BAC77366.1| 622|Homo sapiens putative NFkB activatin... 69 4e-11
AB023163-1|BAA76790.1| 667|Homo sapiens KIAA0946 protein protein. 69 4e-11
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 69 5e-11
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 69 5e-11
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 69 5e-11
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 69 5e-11
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 69 5e-11
L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase prot... 68 9e-11
BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L (2',5'-o... 68 9e-11
BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein. 68 9e-11
BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein. 68 9e-11
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 68 9e-11
AL357148-2|CAI16567.1| 1341|Homo sapiens breast cancer antigen N... 68 9e-11
AL357148-1|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 3... 68 9e-11
AL157387-4|CAH71319.1| 1460|Homo sapiens ankyrin repeat domain 3... 68 9e-11
AL157387-3|CAH71320.1| 1341|Homo sapiens breast cancer antigen N... 68 9e-11
AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L (2',5'-o... 68 9e-11
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 68 1e-10
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 68 1e-10
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 67 2e-10
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 67 2e-10
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 67 2e-10
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 67 2e-10
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 67 2e-10
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 67 2e-10
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 67 2e-10
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 67 2e-10
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 66 3e-10
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 66 3e-10
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 66 3e-10
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 66 3e-10
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 66 3e-10
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 66 3e-10
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 66 3e-10
U16258-1|AAA85819.1| 481|Homo sapiens I kappa BR protein. 66 4e-10
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AF269087-1|AAK27325.1| 1341|Homo sapiens breast cancer antigen N... 66 4e-10
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 66 5e-10
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 66 5e-10
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 66 5e-10
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 5e-10
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 5e-10
BC012056-1|AAH12056.1| 173|Homo sapiens ASB13 protein protein. 66 5e-10
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 66 5e-10
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 66 5e-10
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 66 5e-10
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 66 5e-10
AB024494-1|BAC22089.1| 633|Homo sapiens huntingtin interacting ... 66 5e-10
BC110907-1|AAI10908.1| 515|Homo sapiens PPP1R12B protein protein. 65 9e-10
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 65 9e-10
BC034430-1|AAH34430.1| 386|Homo sapiens PPP1R12B protein protein. 65 9e-10
AL589762-3|CAH73375.1| 982|Homo sapiens protein phosphatase 1, ... 65 9e-10
AL589762-2|CAH73374.1| 386|Homo sapiens protein phosphatase 1, ... 65 9e-10
AL356953-9|CAI15935.1| 982|Homo sapiens protein phosphatase 1, ... 65 9e-10
AL356953-8|CAI15934.1| 386|Homo sapiens protein phosphatase 1, ... 65 9e-10
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 65 9e-10
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 65 9e-10
AF324892-1|AAK00336.1| 982|Homo sapiens myosin phosphatase targ... 65 9e-10
AF324888-1|AAK00337.1| 982|Homo sapiens myosin phosphatase targ... 65 9e-10
AB003062-1|BAA28376.1| 982|Homo sapiens myosin phosphatase targ... 65 9e-10
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 64 1e-09
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 64 1e-09
AL139008-2|CAM15100.1| 1011|Homo sapiens ankyrin repeat domain 1... 64 1e-09
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 64 1e-09
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 64 1e-09
BC056266-1|AAH56266.1| 357|Homo sapiens ANKRD18A protein protein. 64 2e-09
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 64 2e-09
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 64 2e-09
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 64 2e-09
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 64 2e-09
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 63 3e-09
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 63 3e-09
BC069013-1|AAH69013.1| 457|Homo sapiens ANKRD11 protein protein. 63 3e-09
AY533563-1|AAS45544.1| 2663|Homo sapiens ankyrin repeat-containi... 63 3e-09
AY373756-1|AAR25661.1| 2664|Homo sapiens ankyrin repeat-containi... 63 3e-09
AB209186-1|BAD92423.1| 439|Homo sapiens ankyrin repeat domain 1... 63 3e-09
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 63 3e-09
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 63 3e-09
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 63 3e-09
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 62 5e-09
BC020817-1|AAH20817.2| 303|Homo sapiens ANKRD2 protein protein. 62 5e-09
AY337578-1|AAQ17469.1| 233|Homo sapiens ankyrin repeat and SOCS... 62 5e-09
AL359388-5|CAI14193.1| 300|Homo sapiens ankyrin repeat domain 2... 62 5e-09
AL355315-10|CAI15462.1| 300|Homo sapiens ankyrin repeat domain ... 62 5e-09
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 62 5e-09
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 62 6e-09
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 62 6e-09
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 62 6e-09
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 62 6e-09
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 62 6e-09
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 62 6e-09
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 62 6e-09
AF121775-1|AAF24125.1| 366|Homo sapiens nasopharyngeal carcinom... 62 6e-09
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 62 8e-09
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 62 8e-09
AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein. 62 8e-09
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 62 8e-09
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 62 8e-09
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 61 1e-08
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 61 1e-08
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 61 1e-08
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 61 1e-08
M69043-1|AAA16489.1| 317|Homo sapiens MAD3 protein. 61 1e-08
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 61 1e-08
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 61 1e-08
BT007091-1|AAP35754.1| 317|Homo sapiens nuclear factor of kappa... 61 1e-08
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 61 1e-08
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 61 1e-08
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 61 1e-08
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 61 1e-08
BC004983-1|AAH04983.1| 317|Homo sapiens nuclear factor of kappa... 61 1e-08
BC002601-1|AAH02601.1| 317|Homo sapiens nuclear factor of kappa... 61 1e-08
AY496422-1|AAR29599.1| 317|Homo sapiens nuclear factor of kappa... 61 1e-08
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 61 1e-08
AY033600-1|AAK51149.1| 317|Homo sapiens NFKBIA protein. 61 1e-08
AJ249294-1|CAB65556.2| 317|Homo sapiens IkBa protein. 61 1e-08
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 61 1e-08
BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein. 61 1e-08
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 61 1e-08
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 61 1e-08
CR542199-1|CAG46996.1| 260|Homo sapiens RFXANK protein. 60 2e-08
CR456981-1|CAG33262.1| 260|Homo sapiens RFXANK protein. 60 2e-08
BC126188-1|AAI26189.1| 475|Homo sapiens ankyrin repeat, SAM and... 60 2e-08
BC126186-1|AAI26187.1| 475|Homo sapiens ankyrin repeat, SAM and... 60 2e-08
BC114563-1|AAI14564.1| 260|Homo sapiens regulatory factor X-ass... 60 2e-08
BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein. 60 2e-08
BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein. 60 2e-08
BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein. 60 2e-08
BC034963-1|AAH34963.1| 393|Homo sapiens ASZ1 protein protein. 60 2e-08
AK093445-1|BAC04167.1| 475|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK000100-1|BAA90945.1| 420|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF461259-1|AAL68815.1| 475|Homo sapiens GASZ protein. 60 2e-08
AF105427-1|AAD17972.1| 260|Homo sapiens transcription factor RF... 60 2e-08
AF094760-1|AAC69883.1| 260|Homo sapiens RFXANK protein. 60 2e-08
AC003110-1|AAB86654.1| 196|Homo sapiens F14150_1 protein. 60 2e-08
DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein. 60 2e-08
BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein. 60 2e-08
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 60 2e-08
BC060843-1|AAH60843.1| 228|Homo sapiens ANKRD46 protein protein. 60 2e-08
BC050396-1|AAH50396.1| 232|Homo sapiens ANKRD46 protein protein. 60 2e-08
BC027033-1|AAH27033.1| 448|Homo sapiens hypothetical protein MG... 60 2e-08
BC014528-1|AAH14528.1| 335|Homo sapiens ankyrin repeat and SOCS... 60 2e-08
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 60 2e-08
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 60 2e-08
AL691467-2|CAH73760.1| 410|Homo sapiens novel protein protein. 60 2e-08
AL691467-1|CAH73759.1| 448|Homo sapiens novel protein protein. 60 2e-08
AL592424-19|CAI16391.1| 410|Homo sapiens novel protein protein. 60 2e-08
AL592424-18|CAI16392.1| 448|Homo sapiens novel protein protein. 60 2e-08
AL590133-27|CAI13351.1| 448|Homo sapiens novel protein protein. 60 2e-08
AL590133-26|CAI13352.1| 410|Homo sapiens novel protein protein. 60 2e-08
AK096138-1|BAC04707.1| 460|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 60 2e-08
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 60 2e-08
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 60 2e-08
AF156777-1|AAD41894.1| 335|Homo sapiens ASB-1 protein protein. 60 2e-08
AC016999-1|AAX88934.1| 335|Homo sapiens unknown protein. 60 2e-08
AB077205-1|BAD23947.1| 228|Homo sapiens ankyrin repeat small pr... 60 2e-08
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 60 2e-08
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 60 3e-08
BC045621-1|AAH45621.1| 198|Homo sapiens ANKRD42 protein protein. 60 3e-08
AF403033-1|AAL57352.1| 434|Homo sapiens ankyrin repeat domain-c... 60 3e-08
AB032972-1|BAA86460.1| 271|Homo sapiens KIAA1146 protein protein. 60 3e-08
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 59 4e-08
BC035353-1|AAH35353.1| 441|Homo sapiens ankyrin repeat and MYND... 59 4e-08
AL133548-4|CAH71573.1| 214|Homo sapiens osteoclast stimulating ... 59 4e-08
AK222596-1|BAD96316.1| 214|Homo sapiens osteoclast stimulating ... 59 4e-08
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 59 4e-08
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 59 4e-08
BC114558-1|AAI14559.1| 238|Homo sapiens regulatory factor X-ass... 59 6e-08
BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein. 59 6e-08
BC056152-1|AAH56152.1| 622|Homo sapiens zinc finger, DHHC-type ... 59 6e-08
BC012981-1|AAH12981.1| 241|Homo sapiens ANKS6 protein protein. 59 6e-08
AF392450-1|AAL40663.1| 950|Homo sapiens oxysterol-binding prote... 59 6e-08
AF323726-1|AAG53407.2| 927|Homo sapiens OSBP-related protein 1 ... 59 6e-08
AF105428-1|AAD17973.1| 237|Homo sapiens putative protein RFX-Bd... 59 6e-08
AB097027-1|BAC77380.1| 622|Homo sapiens putative MAPK activatin... 59 6e-08
AB097014-1|BAC77367.1| 622|Homo sapiens putative NFkB activatin... 59 6e-08
BC001244-1|AAH01244.1| 252|Homo sapiens ASB9 protein protein. 58 8e-08
AK092230-1|BAC03833.1| 448|Homo sapiens ITOCHONDRIAL PRECURSOR.... 58 8e-08
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 58 1e-07
BC104946-1|AAI04947.1| 309|Homo sapiens ankyrin repeat and SOCS... 58 1e-07
BC093883-1|AAH93883.1| 309|Homo sapiens ankyrin repeat and SOCS... 58 1e-07
BC069555-1|AAH69555.1| 309|Homo sapiens ankyrin repeat and SOCS... 58 1e-07
BC069436-1|AAH69436.1| 309|Homo sapiens ankyrin repeat and SOCS... 58 1e-07
BC028407-1|AAH28407.1| 619|Homo sapiens ankyrin repeat domain 3... 58 1e-07
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 58 1e-07
AL442128-2|CAH73039.1| 420|Homo sapiens ankyrin repeat domain 1... 58 1e-07
AL356317-1|CAI39932.1| 309|Homo sapiens ankyrin repeat and SOCS... 58 1e-07
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 58 1e-07
AL157875-2|CAH70238.1| 420|Homo sapiens ankyrin repeat domain 1... 58 1e-07
AK075298-1|BAC11532.1| 129|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AF403030-1|AAL57349.1| 308|Homo sapiens ankyrin repeat domain-c... 58 1e-07
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 58 1e-07
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 58 1e-07
BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING d... 58 1e-07
BC036020-1|AAH36020.1| 622|Homo sapiens zinc finger, DHHC-type ... 58 1e-07
BC007459-1|AAH07459.1| 217|Homo sapiens OSTF1 protein protein. 58 1e-07
AK001714-1|BAA91856.1| 481|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AB024495-1|BAC22090.1| 622|Homo sapiens huntingtin interacting ... 58 1e-07
U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING dom... 57 2e-07
U63717-1|AAB06396.1| 214|Homo sapiens osteoclast stimulating fa... 57 2e-07
BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 2... 57 2e-07
BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING d... 57 2e-07
BC028093-1|AAH28093.1| 118|Homo sapiens myotrophin protein. 57 2e-07
AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 2... 57 2e-07
AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 2... 57 2e-07
AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING d... 57 2e-07
AF106075-1|AAP97226.1| 118|Homo sapiens V-1 protein protein. 57 2e-07
>BC014558-1|AAH14558.1| 627|Homo sapiens fem-1 homolog b (C.
elegans) protein.
Length = 627
Score = 530 bits (1307), Expect = e-150
Identities = 290/638 (45%), Positives = 392/638 (61%), Gaps = 20/638 (3%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLE 82
V+ AA +G LTL ALL + +I LL G + TPLI AAR+G VR+LLE
Sbjct: 8 VYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLE 67
Query: 83 KFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPL 142
+R V + GTV+FD YVI+GATALWCA+GAGH +VK LV GA+VNH T T STPL
Sbjct: 68 HYR--VQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPL 125
Query: 143 RAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL 202
RAACF+GRLDIVKYLV + A+I ANKY+NTCLMIAAYKG+ DVV++LL+ A + +A
Sbjct: 126 RAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAH 185
Query: 203 CGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVT 262
CGATALHFAAE GH +V L+ A ++ N +GMTPL+ AAE +A VVE+L + +
Sbjct: 186 CGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCD 245
Query: 263 RAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNW 322
R IEA ELLGASFAND+E Y + Y YL+ AM R+ + K PI AY N
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
E +E+E ++ D LHMEGL VRER+LGA D+ HPI++RGAV+AD F++C+
Sbjct: 306 TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK 365
Query: 383 LWRHALHLRQQNQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRL 442
LW HALHLRQ+ + KDLLRFAQVFSQMIH+ + + VL E+ + M R
Sbjct: 366 LWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNR- 424
Query: 443 LKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAM- 501
+K D + ++ Y+ N+ T LYLV ++ + C S+ + + ++ +
Sbjct: 425 VKNISDADVHNAMDNYECNLYTFLYLVCISTKT-----QC----SEEDQCKINKQIYNLI 475
Query: 502 -RGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTP 560
R R G TLLHLA + NTPVDDFHT+DVC FP A ++LLLDCGA+V+A D +
Sbjct: 476 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA 535
Query: 561 LHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVR 620
LH+ ++ Y D + ++ L+ GAH D + TPL S G +E L++
Sbjct: 536 LHI-IVQYNRPISDFLTLH----SIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLK 590
Query: 621 SALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ ++ L C++A + + + Y+ Q+PR L F+ H
Sbjct: 591 TQMKMSLKCLAARAVRANDINYQ-DQIPRTLEEFVGFH 627
>BC010122-1|AAH10122.1| 627|Homo sapiens fem-1 homolog b (C.
elegans) protein.
Length = 627
Score = 530 bits (1307), Expect = e-150
Identities = 290/638 (45%), Positives = 392/638 (61%), Gaps = 20/638 (3%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLE 82
V+ AA +G LTL ALL + +I LL G + TPLI AAR+G VR+LLE
Sbjct: 8 VYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLE 67
Query: 83 KFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPL 142
+R V + GTV+FD YVI+GATALWCA+GAGH +VK LV GA+VNH T T STPL
Sbjct: 68 HYR--VQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPL 125
Query: 143 RAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL 202
RAACF+GRLDIVKYLV + A+I ANKY+NTCLMIAAYKG+ DVV++LL+ A + +A
Sbjct: 126 RAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAH 185
Query: 203 CGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVT 262
CGATALHFAAE GH +V L+ A ++ N +GMTPL+ AAE +A VVE+L + +
Sbjct: 186 CGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCD 245
Query: 263 RAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNW 322
R IEA ELLGASFAND+E Y + Y YL+ AM R+ + K PI AY N
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
E +E+E ++ D LHMEGL VRER+LGA D+ HPI++RGAV+AD F++C+
Sbjct: 306 TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK 365
Query: 383 LWRHALHLRQQNQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRL 442
LW HALHLRQ+ + KDLLRFAQVFSQMIH+ + + VL E+ + M R
Sbjct: 366 LWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNR- 424
Query: 443 LKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAM- 501
+K D + ++ Y+ N+ T LYLV ++ + C S+ + + ++ +
Sbjct: 425 VKNISDADVHNAMDNYECNLYTFLYLVCISTKT-----QC----SEEDQCKINKQIYNLI 475
Query: 502 -RGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTP 560
R R G TLLHLA + NTPVDDFHT+DVC FP A ++LLLDCGA+V+A D +
Sbjct: 476 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA 535
Query: 561 LHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVR 620
LH+ ++ Y D + ++ L+ GAH D + TPL S G +E L++
Sbjct: 536 LHI-IVQYNRPISDFLTLH----SIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLK 590
Query: 621 SALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ ++ L C++A + + + Y+ Q+PR L F+ H
Sbjct: 591 TQMKMSLKCLAARAVRANDINYQ-DQIPRTLEEFVGFH 627
>AF204883-1|AAF69303.1| 627|Homo sapiens FEM1 beta protein.
Length = 627
Score = 530 bits (1307), Expect = e-150
Identities = 290/638 (45%), Positives = 392/638 (61%), Gaps = 20/638 (3%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLE 82
V+ AA +G LTL ALL + +I LL G + TPLI AAR+G VR+LLE
Sbjct: 8 VYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLE 67
Query: 83 KFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPL 142
+R V + GTV+FD YVI+GATALWCA+GAGH +VK LV GA+VNH T T STPL
Sbjct: 68 HYR--VQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPL 125
Query: 143 RAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL 202
RAACF+GRLDIVKYLV + A+I ANKY+NTCLMIAAYKG+ DVV++LL+ A + +A
Sbjct: 126 RAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAH 185
Query: 203 CGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVT 262
CGATALHFAAE GH +V L+ A ++ N +GMTPL+ AAE +A VVE+L + +
Sbjct: 186 CGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCD 245
Query: 263 RAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNW 322
R IEA ELLGASFAND+E Y + Y YL+ AM R+ + K PI AY N
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
E +E+E ++ D LHMEGL VRER+LGA D+ HPI++RGAV+AD F++C+
Sbjct: 306 TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK 365
Query: 383 LWRHALHLRQQNQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRL 442
LW HALHLRQ+ + KDLLRFAQVFSQMIH+ + + VL E+ + M R
Sbjct: 366 LWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNR- 424
Query: 443 LKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAM- 501
+K D + ++ Y+ N+ T LYLV ++ + C S+ + + ++ +
Sbjct: 425 VKNISDADVHNAMDNYECNLYTFLYLVCISTKT-----QC----SEEDQCKINKQIYNLI 475
Query: 502 -RGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTP 560
R R G TLLHLA + NTPVDDFHT+DVC FP A ++LLLDCGA+V+A D +
Sbjct: 476 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA 535
Query: 561 LHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVR 620
LH+ ++ Y D + ++ L+ GAH D + TPL S G +E L++
Sbjct: 536 LHI-IVQYNRPISDFLTLH----SIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLK 590
Query: 621 SALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ ++ L C++A + + + Y+ Q+PR L F+ H
Sbjct: 591 TQMKMSLKCLAARAVRANDINYQ-DQIPRTLEEFVGFH 627
>AF178632-1|AAF05314.1| 627|Homo sapiens FEM-1-like death receptor
binding protein protein.
Length = 627
Score = 530 bits (1307), Expect = e-150
Identities = 290/638 (45%), Positives = 392/638 (61%), Gaps = 20/638 (3%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLE 82
V+ AA +G LTL ALL + +I LL G + TPLI AAR+G VR+LLE
Sbjct: 8 VYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLE 67
Query: 83 KFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPL 142
+R V + GTV+FD YVI+GATALWCA+GAGH +VK LV GA+VNH T T STPL
Sbjct: 68 HYR--VQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPL 125
Query: 143 RAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL 202
RAACF+GRLDIVKYLV + A+I ANKY+NTCLMIAAYKG+ DVV++LL+ A + +A
Sbjct: 126 RAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAH 185
Query: 203 CGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVT 262
CGATALHFAAE GH +V L+ A ++ N +GMTPL+ AAE +A VVE+L + +
Sbjct: 186 CGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCD 245
Query: 263 RAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNW 322
R IEA ELLGASFAND+E Y + Y YL+ AM R+ + K PI AY N
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
E +E+E ++ D LHMEGL VRER+LGA D+ HPI++RGAV+AD F++C+
Sbjct: 306 TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK 365
Query: 383 LWRHALHLRQQNQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRL 442
LW HALHLRQ+ + KDLLRFAQVFSQMIH+ + + VL E+ + M R
Sbjct: 366 LWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNR- 424
Query: 443 LKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAM- 501
+K D + ++ Y+ N+ T LYLV ++ + C S+ + + ++ +
Sbjct: 425 VKNISDADVHNAMDNYECNLYTFLYLVCISTKT-----QC----SEEDQCKINKQIYNLI 475
Query: 502 -RGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTP 560
R R G TLLHLA + NTPVDDFHT+DVC FP A ++LLLDCGA+V+A D +
Sbjct: 476 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA 535
Query: 561 LHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVR 620
LH+ ++ Y D + ++ L+ GAH D + TPL S G +E L++
Sbjct: 536 LHI-IVQYNRPISDFLTLH----SIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLK 590
Query: 621 SALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ ++ L C++A + + + Y+ Q+PR L F+ H
Sbjct: 591 TQMKMSLKCLAARAVRANDINYQ-DQIPRTLEEFVGFH 627
>AB007856-1|BAA23692.2| 627|Homo sapiens KIAA0396 protein.
Length = 627
Score = 530 bits (1307), Expect = e-150
Identities = 290/638 (45%), Positives = 392/638 (61%), Gaps = 20/638 (3%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLE 82
V+ AA +G LTL ALL + +I LL G + TPLI AAR+G VR+LLE
Sbjct: 8 VYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLE 67
Query: 83 KFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPL 142
+R V + GTV+FD YVI+GATALWCA+GAGH +VK LV GA+VNH T T STPL
Sbjct: 68 HYR--VQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPL 125
Query: 143 RAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL 202
RAACF+GRLDIVKYLV + A+I ANKY+NTCLMIAAYKG+ DVV++LL+ A + +A
Sbjct: 126 RAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAH 185
Query: 203 CGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVT 262
CGATALHFAAE GH +V L+ A ++ N +GMTPL+ AAE +A VVE+L + +
Sbjct: 186 CGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCD 245
Query: 263 RAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNW 322
R IEA ELLGASFAND+E Y + Y YL+ AM R+ + K PI AY N
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
E +E+E ++ D LHMEGL VRER+LGA D+ HPI++RGAV+AD F++C+
Sbjct: 306 TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK 365
Query: 383 LWRHALHLRQQNQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRL 442
LW HALHLRQ+ + KDLLRFAQVFSQMIH+ + + VL E+ + M R
Sbjct: 366 LWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNR- 424
Query: 443 LKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAM- 501
+K D + ++ Y+ N+ T LYLV ++ + C S+ + + ++ +
Sbjct: 425 VKNISDADVHNAMDNYECNLYTFLYLVCISTKT-----QC----SEEDQCKINKQIYNLI 475
Query: 502 -RGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTP 560
R R G TLLHLA + NTPVDDFHT+DVC FP A ++LLLDCGA+V+A D +
Sbjct: 476 HLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSA 535
Query: 561 LHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVR 620
LH+ ++ Y D + ++ L+ GAH D + TPL S G +E L++
Sbjct: 536 LHI-IVQYNRPISDFLTLH----SIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLK 590
Query: 621 SALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ ++ L C++A + + + Y+ Q+PR L F+ H
Sbjct: 591 TQMKMSLKCLAARAVRANDINYQ-DQIPRTLEEFVGFH 627
>BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C.
elegans) protein.
Length = 617
Score = 344 bits (846), Expect = 5e-94
Identities = 234/652 (35%), Positives = 347/652 (53%), Gaps = 50/652 (7%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L+ VF AARDG L LL K +E+ L++ ++G TPL+ AAR+G V
Sbjct: 3 LKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEK--TNGA--TPLLMAARYGHLDMVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
LLE+ + E G+V FD IEGA LW AS AGHL +V+ L+ GA VN+ T T
Sbjct: 59 FLLEQCSASI--EVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTN 116
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
STPLRAACF+G L+IVKYLV H AD+ +N++ +TCLMI+ YKG+ ++ Q+LL+ GA V+
Sbjct: 117 STPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
+++ G TALH AE G ++ LL + AKM + GMTPL A+ ++V+ L
Sbjct: 177 RKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH 236
Query: 259 PEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKR-PSTPIP 317
+ ++ E I A ELLGA+F + K L A +Y +AM MRY R + K P T I
Sbjct: 237 AQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIM 294
Query: 318 AYDNWKETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARF 377
AYD KE + EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F
Sbjct: 295 AYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNF 354
Query: 378 DRCLALWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH------IGIELPLAQVCYV 427
RC+ LW++AL ++Q N LL FA++FS M+ +G + + +
Sbjct: 355 KRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGI 414
Query: 428 LEACAEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLS 487
L E+ R +K+ P DP L + + L+L+ LLE C
Sbjct: 415 LCKSVLEIERAIKQTQCP---ADPLQL----NKALSIILHLIC----LLE-KVPCTLEQD 462
Query: 488 QGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCG 547
+ R F R ++ + LHLA D+NT + VC+FP + + +L++CG
Sbjct: 463 HFKKQTIYR--FLKLHPRGKNNFSPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECG 518
Query: 548 ADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL 607
ADV+ D + +PLH+A ++ N ++ L+ GAH DA +L T
Sbjct: 519 ADVNVRDSDDNSPLHIAALN-----------NHP--DIMNLLIKSGAHFDATNLHKQTAS 565
Query: 608 -VASIGGPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ A++L++ L C++A V+ HR+ Y+ +P L F+ +H
Sbjct: 566 DLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYK-GHIPEKLETFVSLH 616
>AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein.
Length = 617
Score = 344 bits (846), Expect = 5e-94
Identities = 234/652 (35%), Positives = 347/652 (53%), Gaps = 50/652 (7%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L+ VF AARDG L LL K +E+ L++ ++G TPL+ AAR+G V
Sbjct: 3 LKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEK--TNGA--TPLLMAARYGHLDMVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
LLE+ + E G+V FD IEGA LW AS AGHL +V+ L+ GA VN+ T T
Sbjct: 59 FLLEQCSASI--EVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTN 116
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
STPLRAACF+G L+IVKYLV H AD+ +N++ +TCLMI+ YKG+ ++ Q+LL+ GA V+
Sbjct: 117 STPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
+++ G TALH AE G ++ LL + AKM + GMTPL A+ ++V+ L
Sbjct: 177 RKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH 236
Query: 259 PEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKR-PSTPIP 317
+ ++ E I A ELLGA+F + K L A +Y +AM MRY R + K P T I
Sbjct: 237 AQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIM 294
Query: 318 AYDNWKETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARF 377
AYD KE + EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F
Sbjct: 295 AYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNF 354
Query: 378 DRCLALWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH------IGIELPLAQVCYV 427
RC+ LW++AL ++Q N LL FA++FS M+ +G + + +
Sbjct: 355 KRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGI 414
Query: 428 LEACAEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLS 487
L E+ R +K+ P DP L + + L+L+ LLE C
Sbjct: 415 LCKSVLEIERAIKQTQCP---ADPLQL----NKALSIILHLIC----LLE-KVPCTLEQD 462
Query: 488 QGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCG 547
+ R F R ++ + LHLA D+NT + VC+FP + + +L++CG
Sbjct: 463 HFKKQTIYR--FLKLHPRGKNNFSPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECG 518
Query: 548 ADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL 607
ADV+ D + +PLH+A ++ N ++ L+ GAH DA +L T
Sbjct: 519 ADVNVRDSDDNSPLHIAALN-----------NHP--DIMNLLIKSGAHFDATNLHKQTAS 565
Query: 608 -VASIGGPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ A++L++ L C++A V+ HR+ Y+ +P L F+ +H
Sbjct: 566 DLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYK-GHIPEKLETFVSLH 616
>AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein.
Length = 617
Score = 344 bits (846), Expect = 5e-94
Identities = 234/652 (35%), Positives = 347/652 (53%), Gaps = 50/652 (7%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L+ VF AARDG L LL K +E+ L++ ++G TPL+ AAR+G V
Sbjct: 3 LKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEK--TNGA--TPLLMAARYGHLDMVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
LLE+ + E G+V FD IEGA LW AS AGHL +V+ L+ GA VN+ T T
Sbjct: 59 FLLEQCSASI--EVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTN 116
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
STPLRAACF+G L+IVKYLV H AD+ +N++ +TCLMI+ YKG+ ++ Q+LL+ GA V+
Sbjct: 117 STPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
+++ G TALH AE G ++ LL + AKM + GMTPL A+ ++V+ L
Sbjct: 177 RKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH 236
Query: 259 PEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKR-PSTPIP 317
+ ++ E I A ELLGA+F + K L A +Y +AM MRY R + K P T I
Sbjct: 237 AQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIM 294
Query: 318 AYDNWKETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARF 377
AYD KE + EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F
Sbjct: 295 AYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNF 354
Query: 378 DRCLALWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH------IGIELPLAQVCYV 427
RC+ LW++AL ++Q N LL FA++FS M+ +G + + +
Sbjct: 355 KRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGI 414
Query: 428 LEACAEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLS 487
L E+ R +K+ P DP L + + L+L+ LLE C
Sbjct: 415 LCKSVLEIERAIKQTQCP---ADPLQL----NKALSIILHLIC----LLE-KVPCTLEQD 462
Query: 488 QGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCG 547
+ R F R ++ + LHLA D+NT + VC+FP + + +L++CG
Sbjct: 463 HFKKQTIYR--FLKLHPRGKNNFSPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECG 518
Query: 548 ADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL 607
ADV+ D + +PLH+A ++ N ++ L+ GAH DA +L T
Sbjct: 519 ADVNVRDSDDNSPLHIAALN-----------NHP--DIMNLLIKSGAHFDATNLHKQTAS 565
Query: 608 -VASIGGPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ A++L++ L C++A V+ HR+ Y+ +P L F+ +H
Sbjct: 566 DLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYK-GHIPEKLETFVSLH 616
>AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein.
Length = 617
Score = 344 bits (846), Expect = 5e-94
Identities = 234/652 (35%), Positives = 347/652 (53%), Gaps = 50/652 (7%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L+ VF AARDG L LL K +E+ L++ ++G TPL+ AAR+G V
Sbjct: 3 LKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEK--TNGA--TPLLMAARYGHLDMVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
LLE+ + E G+V FD IEGA LW AS AGHL +V+ L+ GA VN+ T T
Sbjct: 59 FLLEQCSASI--EVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTN 116
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
STPLRAACF+G L+IVKYLV H AD+ +N++ +TCLMI+ YKG+ ++ Q+LL+ GA V+
Sbjct: 117 STPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
+++ G TALH AE G ++ LL + AKM + GMTPL A+ ++V+ L
Sbjct: 177 RKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH 236
Query: 259 PEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKR-PSTPIP 317
+ ++ E I A ELLGA+F + K L A +Y +AM MRY R + K P T I
Sbjct: 237 AQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIM 294
Query: 318 AYDNWKETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARF 377
AYD KE + EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F
Sbjct: 295 AYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNF 354
Query: 378 DRCLALWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH------IGIELPLAQVCYV 427
RC+ LW++AL ++Q N LL FA++FS M+ +G + + +
Sbjct: 355 KRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGI 414
Query: 428 LEACAEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLS 487
L E+ R +K+ P DP L + + L+L+ LLE C
Sbjct: 415 LCKSVLEIERAIKQTQCP---ADPLQL----NKALSIILHLIC----LLE-KVPCTLEQD 462
Query: 488 QGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCG 547
+ R F R ++ + LHLA D+NT + VC+FP + + +L++CG
Sbjct: 463 HFKKQTIYR--FLKLHPRGKNNFSPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECG 518
Query: 548 ADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL 607
ADV+ D + +PLH+A ++ N ++ L+ GAH DA +L T
Sbjct: 519 ADVNVRDSDDNSPLHIAALN-----------NHP--DIMNLLIKSGAHFDATNLHKQTAS 565
Query: 608 -VASIGGPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ A++L++ L C++A V+ HR+ Y+ +P L F+ +H
Sbjct: 566 DLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYK-GHIPEKLETFVSLH 616
>AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1|)
sex-determination protein homolog Fem1a [Mus musculus
protein.
Length = 271
Score = 213 bits (521), Expect = 1e-54
Identities = 117/263 (44%), Positives = 163/263 (61%), Gaps = 6/263 (2%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L+ VF AARDG L LL K +E+ L++ ++G TPL+ AAR+G V
Sbjct: 3 LKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEK--TNGA--TPLLMAARYGHLDMVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
LLE+ + E G+V FD IEGA LW AS AGHL +V+ L+ GA VN+ T T
Sbjct: 59 FLLEQCSASI--EVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTN 116
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
STPLRAACF+G L+IVKYLV H AD+ +N++ +TCLMI+ YKG+ ++ Q+LL+ GA V+
Sbjct: 117 STPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
+++ G TALH AE G ++ LL + AKM + GMTPL A+ ++V+ L
Sbjct: 177 RKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHH 236
Query: 259 PEVTRAEAIEAYELLGASFANDK 281
+ ++ E I A ELLGA+F + K
Sbjct: 237 AQTSKTERINALELLGATFVDKK 259
>BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C.
elegans) protein.
Length = 669
Score = 192 bits (468), Expect = 3e-48
Identities = 107/238 (44%), Positives = 148/238 (62%), Gaps = 7/238 (2%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
LR V+ AARDG L LL + +E+D+L +V G TPL+ AAR+G V
Sbjct: 3 LRTAVYNAARDGKLQLLQKLLSGRSREELDELTG-EVAGGG---TPLLIAARYGHLDVVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
L+++ V E G+V FD IEGA LW AS AGHL +V+ L++ GA VN TRT
Sbjct: 59 YLVDRCGASV--EAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTN 116
Query: 139 STPLRAACFEGRLDIVKYLV-RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARV 197
STPLRAACF+G L++V+YLV H AD+ AN++ +TCLMI+ YKG+ ++ ++LL+ GA+V
Sbjct: 117 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 176
Query: 198 DDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+ R+ G TALH AE G ++ LL A+M + GMTPL A+ ++VE L
Sbjct: 177 NRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL 234
Score = 190 bits (462), Expect = 2e-47
Identities = 179/592 (30%), Positives = 284/592 (47%), Gaps = 78/592 (13%)
Query: 106 ATALWCASGAGHLAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
+T L A GHL +V+ LV + AD+ A R T L +C++G +I +YL+ GA +
Sbjct: 117 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 176
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ + NT L A G L+++Q LL AR++ R G T L A+ GH +V L+
Sbjct: 177 NRRSAKGNTALHDCAESGSLEILQLLLGCKARME-RDGYGMTPLLAASVTGHTNIVEYLI 235
Query: 225 DH--------GAKM---LTNENGMTPLQCA----AERARASVVEILAARP-----EVTRA 264
G + L E+ T CA A +S E L +R
Sbjct: 236 QEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSRE 295
Query: 265 EAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTP--IPAYDNW 322
A+EA ELLGA++ + K L A ++ RAM +R+ GE L +P P + AYD
Sbjct: 296 AAVEALELLGATYVDKKRD--LLGALKHWRRAMELRHQG--GEYLPKPEPPQLVLAYDYS 351
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
+E T EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F+RC+
Sbjct: 352 REVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIR 411
Query: 383 LWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH-------IGIELPLAQVCYVLEAC 431
LW++AL ++Q N L FA++FS ++ +G ++ A + VL
Sbjct: 412 LWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKG 471
Query: 432 AEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTR 491
E+ R ++ P+ DS ++ + L+L+ + + +E + + E Q
Sbjct: 472 VREVERALQL-----PREPGDS--AQFTKALAIILHLLYLLEK-VECTPSQEHLKHQ--- 520
Query: 492 SAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVD 551
+ R A RG ++G T LH+A D++T + V +FP ++LLDCGAD D
Sbjct: 521 TVYRLLKCAPRG---KNGFTPLHMAVDKDT--TNVGRYPVGRFPSLHVVKVLLDCGADPD 575
Query: 552 AADMNRRTPLHVALISYQLTSDDREQYNEAFC-GVVCELLSRGAHVDAMDLDGITPLVAS 610
+ D + TPLH+A Q N C ++ L+ GAH+DA + T
Sbjct: 576 SRDFDNNTPLHIA-----------AQNN---CPAIMNALIEAGAHMDATNAFKKTAYELL 621
Query: 611 IGGPAESLVRSALRP----RLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ L R ++P L C++A L +++ Y+ +P DL AF+ +H
Sbjct: 622 ---DEKLLARGTMQPFNYVTLQCLAARALDKNKIPYK-GFIPEDLEAFIELH 669
>AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E receptor
4-associated protein protein.
Length = 669
Score = 192 bits (468), Expect = 3e-48
Identities = 107/238 (44%), Positives = 148/238 (62%), Gaps = 7/238 (2%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
LR V+ AARDG L LL + +E+D+L +V G TPL+ AAR+G V
Sbjct: 3 LRTAVYNAARDGKLQLLQKLLSGRSREELDELTG-EVAGGG---TPLLIAARYGHLDVVE 58
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
L+++ V E G+V FD IEGA LW AS AGHL +V+ L++ GA VN TRT
Sbjct: 59 YLVDRCGASV--EAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTN 116
Query: 139 STPLRAACFEGRLDIVKYLV-RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARV 197
STPLRAACF+G L++V+YLV H AD+ AN++ +TCLMI+ YKG+ ++ ++LL+ GA+V
Sbjct: 117 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 176
Query: 198 DDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+ R+ G TALH AE G ++ LL A+M + GMTPL A+ ++VE L
Sbjct: 177 NRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL 234
Score = 190 bits (462), Expect = 2e-47
Identities = 179/592 (30%), Positives = 284/592 (47%), Gaps = 78/592 (13%)
Query: 106 ATALWCASGAGHLAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
+T L A GHL +V+ LV + AD+ A R T L +C++G +I +YL+ GA +
Sbjct: 117 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 176
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ + NT L A G L+++Q LL AR++ R G T L A+ GH +V L+
Sbjct: 177 NRRSAKGNTALHDCAESGSLEILQLLLGCKARME-RDGYGMTPLLAASVTGHTNIVEYLI 235
Query: 225 DH--------GAKM---LTNENGMTPLQCA----AERARASVVEILAARP-----EVTRA 264
G + L E+ T CA A +S E L +R
Sbjct: 236 QEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSRE 295
Query: 265 EAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTP--IPAYDNW 322
A+EA ELLGA++ + K L A ++ RAM +R+ GE L +P P + AYD
Sbjct: 296 AAVEALELLGATYVDKKRD--LLGALKHWRRAMELRHQG--GEYLPKPEPPQLVLAYDYS 351
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
+E T EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F+RC+
Sbjct: 352 REVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIR 411
Query: 383 LWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH-------IGIELPLAQVCYVLEAC 431
LW++AL ++Q N L FA++FS ++ +G ++ A + VL
Sbjct: 412 LWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKG 471
Query: 432 AEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTR 491
E+ R ++ P+ DS ++ + L+L+ + + +E + + E Q
Sbjct: 472 VREVERALQL-----PREPGDS--AQFTKALAIILHLLYLLEK-VECTPSQEHLKHQ--- 520
Query: 492 SAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVD 551
+ R A RG ++G T LH+A D++T + V +FP ++LLDCGAD D
Sbjct: 521 TVYRLLKCAPRG---KNGFTPLHMAVDKDT--TNVGRYPVGRFPSLHVVKVLLDCGADPD 575
Query: 552 AADMNRRTPLHVALISYQLTSDDREQYNEAFC-GVVCELLSRGAHVDAMDLDGITPLVAS 610
+ D + TPLH+A Q N C ++ L+ GAH+DA + T
Sbjct: 576 SRDFDNNTPLHIA-----------AQNN---CPAIMNALIEAGAHMDATNAFKKTAYELL 621
Query: 611 IGGPAESLVRSALRP----RLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ L R ++P L C++A L +++ Y+ +P DL AF+ +H
Sbjct: 622 ---DEKLLARGTMQPFNYVTLQCLAARALDKNKIPYK-GFIPEDLEAFIELH 669
>AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determining
protein protein.
Length = 668
Score = 192 bits (468), Expect = 3e-48
Identities = 107/238 (44%), Positives = 148/238 (62%), Gaps = 7/238 (2%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
LR V+ AARDG L LL + +E+D+L +V G TPL+ AAR+G V
Sbjct: 2 LRTAVYNAARDGKLQLLQKLLSGRSREELDELTG-EVAGGG---TPLLIAARYGHLDVVE 57
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
L+++ V E G+V FD IEGA LW AS AGHL +V+ L++ GA VN TRT
Sbjct: 58 YLVDRCGASV--EAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRTN 115
Query: 139 STPLRAACFEGRLDIVKYLV-RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARV 197
STPLRAACF+G L++V+YLV H AD+ AN++ +TCLMI+ YKG+ ++ ++LL+ GA+V
Sbjct: 116 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 175
Query: 198 DDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+ R+ G TALH AE G ++ LL A+M + GMTPL A+ ++VE L
Sbjct: 176 NRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYL 233
Score = 190 bits (462), Expect = 2e-47
Identities = 179/592 (30%), Positives = 284/592 (47%), Gaps = 78/592 (13%)
Query: 106 ATALWCASGAGHLAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
+T L A GHL +V+ LV + AD+ A R T L +C++G +I +YL+ GA +
Sbjct: 116 STPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQV 175
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ + NT L A G L+++Q LL AR++ R G T L A+ GH +V L+
Sbjct: 176 NRRSAKGNTALHDCAESGSLEILQLLLGCKARME-RDGYGMTPLLAASVTGHTNIVEYLI 234
Query: 225 DH--------GAKM---LTNENGMTPLQCA----AERARASVVEILAARP-----EVTRA 264
G + L E+ T CA A +S E L +R
Sbjct: 235 QEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSRE 294
Query: 265 EAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTP--IPAYDNW 322
A+EA ELLGA++ + K L A ++ RAM +R+ GE L +P P + AYD
Sbjct: 295 AAVEALELLGATYVDKKRD--LLGALKHWRRAMELRHQG--GEYLPKPEPPQLVLAYDYS 350
Query: 323 KETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLA 382
+E T EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F+RC+
Sbjct: 351 REVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIR 410
Query: 383 LWRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH-------IGIELPLAQVCYVLEAC 431
LW++AL ++Q N L FA++FS ++ +G ++ A + VL
Sbjct: 411 LWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKG 470
Query: 432 AEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTR 491
E+ R ++ P+ DS ++ + L+L+ + + +E + + E Q
Sbjct: 471 VREVERALQL-----PREPGDS--AQFTKALAIILHLLYLLEK-VECTPSQEHLKHQ--- 519
Query: 492 SAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVD 551
+ R A RG ++G T LH+A D++T + V +FP ++LLDCGAD D
Sbjct: 520 TVYRLLKCAPRG---KNGFTPLHMAVDKDT--TNVGRYPVGRFPSLHVVKVLLDCGADPD 574
Query: 552 AADMNRRTPLHVALISYQLTSDDREQYNEAFC-GVVCELLSRGAHVDAMDLDGITPLVAS 610
+ D + TPLH+A Q N C ++ L+ GAH+DA + T
Sbjct: 575 SRDFDNNTPLHIA-----------AQNN---CPAIMNALIEAGAHMDATNAFKKTAYELL 620
Query: 611 IGGPAESLVRSALRP----RLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
+ L R ++P L C++A L +++ Y+ +P DL AF+ +H
Sbjct: 621 ---DEKLLARGTMQPFNYVTLQCLAARALDKNKIPYK-GFIPEDLEAFIELH 668
>AL365409-1|CAB96953.1| 317|Homo sapiens similar to (NP_034322.1|)
sex-determination protein homolog Fem1a [Mus musculus
protein.
Length = 317
Score = 120 bits (290), Expect = 1e-26
Identities = 100/346 (28%), Positives = 164/346 (47%), Gaps = 41/346 (11%)
Query: 324 ETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLAL 383
E + EE+E L D + M+ L +RER+LG + PD + I +RGAV+AD F RC+ L
Sbjct: 1 EVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINL 60
Query: 384 WRHALHLRQQN----QVSVVKDLLRFAQVFSQMIH------IGIELPLAQVCYVLEACAE 433
W++AL ++Q N LL FA++FS M+ +G + + +L
Sbjct: 61 WKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVL 120
Query: 434 ELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSA 493
E+ R +K+ P DP L + + L+L+ LLE C +
Sbjct: 121 EIERAIKQTQCP---ADPLQL----NKALSIILHLIC----LLE-KVPCTLEQDHFKKQT 168
Query: 494 ARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAA 553
R F R ++ + LHLA D+NT + VC+FP + + +L++CGADV+
Sbjct: 169 IYR--FLKLHPRGKNNFSPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECGADVNVR 224
Query: 554 DMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL-VASIG 612
D + +PLH+A ++ N ++ L+ GAH DA +L T +
Sbjct: 225 DSDDNSPLHIAALN-----------NHP--DIMNLLIKSGAHFDATNLHKQTASDLLDEK 271
Query: 613 GPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMH 658
A++L++ L C++A V+ HR+ Y+ +P L F+ +H
Sbjct: 272 EIAKNLIQPINHTTLQCLAARVIVNHRIYYK-GHIPEKLETFVSLH 316
Score = 36.3 bits (80), Expect = 0.35
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 15/98 (15%)
Query: 151 LDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHF 210
L + L+ GAD++ + +N+ L IAA + D++ L+ SGA HF
Sbjct: 208 LQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGA-------------HF 254
Query: 211 AAECGHAAVVCSLLDHG--AKMLTNENGMTPLQCAAER 246
A H LLD AK L T LQC A R
Sbjct: 255 DATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAAR 292
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
L + L++ GADVN ++PL A DI+ L++ GA N + T
Sbjct: 208 LQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQT 263
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens
cDNA FLJ45589 fis, clone BRTHA3014547, weakly similar
to Ankyrin 1. ).
Length = 1375
Score = 116 bits (279), Expect = 3e-25
Identities = 97/266 (36%), Positives = 137/266 (51%), Gaps = 31/266 (11%)
Query: 1 MEREDNDRLVL-----FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDV 55
+ERED+ R +L N+ ++ R + AA G SL + LL + D L I+
Sbjct: 468 LEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSG-SLDVVNLLVSRGAD-----LEIE- 520
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
D TPL AAR G V L+ C + +G TAL A+
Sbjct: 521 --DAHGHTPLTLAARQGHTKVVNCLIG------C-----GANINHTDQDGWTALRSAAWG 567
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH +V L+ AG V+ A T LRAA + GR DIV L++HGA+++KA+ T L
Sbjct: 568 GHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTAL 627
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC-----GHAAVVCSLLDHGAKM 230
+ AAY G+ ++V+ LLD GA V+ + G TAL AA C GHA+VV L+D GA++
Sbjct: 628 IAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEV 687
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+++GMTPL AA VV++L
Sbjct: 688 DHCDKDGMTPLLVAAYEGHVDVVDLL 713
Score = 94.7 bits (225), Expect = 9e-19
Identities = 76/209 (36%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C+D T L AA GRE V LL+ K D EG TAL A+
Sbjct: 585 CADADSRTALRAAAWGGREDIVLNLLQ--------HGAEVNKADN---EGRTALIAAAYM 633
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACF-----EGRLDIVKYLVRHGADIHKANKY 170
GH IV+ L+ GA+VNH T L A +G +V L+ GA++ +K
Sbjct: 634 GHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKD 693
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L++AAY+G++DVV LL+ GA VD G T L AA GHA+VV +LL GA +
Sbjct: 694 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 753
Query: 231 -LTNENGMTPLQCAAERARASVVEILAAR 258
+ G T L A+ + VV L R
Sbjct: 754 DSIDSEGRTVLSIASAQGNVEVVRTLLDR 782
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/153 (31%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G L+ + L + + ++ GA+V + T L +C++G +++V+ L+ + AD
Sbjct: 891 DGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHAD 950
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ A+ + L AA++G++ VVQ L++ GA VD GATAL AA+ GH VV L
Sbjct: 951 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
L+HGA ++ G T ++ AA+ + ++++L
Sbjct: 1011 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 1043
Score = 88.2 bits (209), Expect = 8e-17
Identities = 54/149 (36%), Positives = 76/149 (51%), Gaps = 1/149 (0%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL + GH ++V L+ GA+V+H + TPL A +EG +D+V L+ GAD+
Sbjct: 664 ALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHT 723
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L+ AA G+ VV LL GA VD G T L A+ G+ VV +LLD G
Sbjct: 724 DNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 783
Query: 228 A-KMLTNENGMTPLQCAAERARASVVEIL 255
+ ++ G TPL AA + E L
Sbjct: 784 LDENHRDDAGWTPLHMAAFEGHRLICEAL 812
Score = 87.8 bits (208), Expect = 1e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL + GH+ +V+ L+ ADVN A + L++A ++G + +V+ L+ HGA
Sbjct: 924 EGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAV 983
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T L IAA +G++DVVQ LL+ GA + G TA+ AA+ GH+ ++ L
Sbjct: 984 VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 1043
Query: 224 LDHGAKMLTNENGMTP 239
+GA L NG +P
Sbjct: 1044 EKYGASSL---NGCSP 1056
Score = 87.4 bits (207), Expect = 1e-16
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 15/204 (7%)
Query: 28 RDGMSLTLYALLYEKKTDEIDDLLN--IDVC-SDGVKCTPLITAARHGREGAVRILLEKF 84
+DGM+ L A YE D +D LL DV +D TPL+ AA G V LL
Sbjct: 692 KDGMTPLLVAA-YEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLF-- 748
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D EG T L AS G++ +V+ L+ G D NH TPL
Sbjct: 749 ---------WGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHM 799
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A FEG I + L+ GA ++ + ++A+ +G+ D VQ LL++ + +D R G
Sbjct: 800 AAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDG 859
Query: 205 ATALHFAAECGHAAVVCSLLDHGA 228
AL AA GH +V L HGA
Sbjct: 860 RNALRVAALEGHRDIVELLFSHGA 883
Score = 85.8 bits (203), Expect = 4e-16
Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH+ +V L++ GADV+H TPL AA G +V L+ GA
Sbjct: 693 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 752
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + T L IA+ +G ++VV+ LLD G + R G T LH AA GH + +L
Sbjct: 753 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 812
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEIL 255
++ GA+ TNE +G P A++ V+IL
Sbjct: 813 IEQGAR--TNEIDNDGRIPFILASQEGHYDCVQIL 845
Score = 78.6 bits (185), Expect = 7e-14
Identities = 71/232 (30%), Positives = 110/232 (47%), Gaps = 23/232 (9%)
Query: 26 AARDGMSLTLYALLYE-KKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKF 84
AA +G L AL+ + +T+EID+ DG P I A++ G V+ILLE
Sbjct: 800 AAFEGHRLICEALIEQGARTNEIDN--------DGR--IPFILASQEGHYDCVQILLEN- 848
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D+ +G AL A+ GH IV+ L GADVN L
Sbjct: 849 ----------KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI 898
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
E +L + +Y + +GA++ ++ T L ++ ++G++++VQ L+ A V+
Sbjct: 899 LALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEK 958
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+AL AA GH VV L++HGA + T G T L AA+ VV++L
Sbjct: 959 RSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010
Score = 72.5 bits (170), Expect = 4e-12
Identities = 56/165 (33%), Positives = 84/165 (50%), Gaps = 4/165 (2%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
+++ LVKAGA VN S +R A R D ++ L+ +GA +++ + T L AA
Sbjct: 442 VLQLLVKAGAHVNSEDDRTSCIVRQAL--EREDSIRTLLDNGASVNQCDSNGRTLLANAA 499
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
Y G LDVV L+ GA ++ G T L AA GH VV L+ GA + T+++G T
Sbjct: 500 YSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWT 559
Query: 239 PLQCAAERARASVVE-ILAARPEVTRAEAIEAYELLGASFANDKE 282
L+ AA VV +L A +V A+A L A++ ++
Sbjct: 560 ALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGRED 604
Score = 68.1 bits (159), Expect = 9e-11
Identities = 60/211 (28%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Query: 47 IDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEG 105
ID +D C DG+ TPL+ AA G V +LLE G D G
Sbjct: 681 IDRGAEVDHCDKDGM--TPLLVAAYEGHVDVVDLLLE-----------GGADVDHTDNNG 727
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
T L A+ GH ++V L+ GA V+ T L A +G +++V+ L+ G D +
Sbjct: 728 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 787
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T L +AA++G+ + + L++ GAR ++ G A++ GH V LL+
Sbjct: 788 HRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 847
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + + +G L+ AA +VE+L
Sbjct: 848 NKSNIDQRGYDGRNALRVAALEGHRDIVELL 878
Score = 60.5 bits (140), Expect = 2e-08
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 1/154 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH I + L++ GA N P A EG D V+ L+ + ++I
Sbjct: 793 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 852
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ L +AA +G+ D+V+ L GA V+ + G L+ A + L
Sbjct: 853 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 912
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
++GA + ++ G T L + + +V++L A
Sbjct: 913 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIA 946
Score = 40.7 bits (91), Expect = 0.016
Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
LLD GA+V+ D++ RT L VA + + + VV L+ RGA VD D D
Sbjct: 642 LLDHGAEVNHEDVDGRTALSVAALCVPAS--------KGHASVVSLLIDRGAEVDHCDKD 693
Query: 603 GITPLVAS 610
G+TPL+ +
Sbjct: 694 GMTPLLVA 701
Score = 36.3 bits (80), Expect = 0.35
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LL+D GA+VD D + TPL VA +Y E VV LL GA VD D
Sbjct: 679 LLIDRGAEVDHCDKDGMTPLLVA--AY-----------EGHVDVVDLLLEGGADVDHTDN 725
Query: 602 DGITPLVASIGGPAESLVRSAL 623
+G TPL+A+ S+V + L
Sbjct: 726 NGRTPLLAAASMGHASVVNTLL 747
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 114 bits (274), Expect = 1e-24
Identities = 96/266 (36%), Positives = 136/266 (51%), Gaps = 31/266 (11%)
Query: 1 MEREDNDRLVL-----FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDV 55
+ERED+ R +L N+ ++ R + AA G SL + LL + D L I+
Sbjct: 373 LEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSG-SLDVVNLLVSRGAD-----LEIE- 425
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
D TPL AAR G V L+ C + +G TAL A+
Sbjct: 426 --DAHGHTPLTLAARQGHTKVVNCLIG------C-----GANINHTDQDGWTALRSAAWG 472
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH +V L+ AG V+ A T LRAA + G DIV L++HGA+++KA+ T L
Sbjct: 473 GHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTAL 532
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC-----GHAAVVCSLLDHGAKM 230
+ AAY G+ ++V+ LLD GA V+ + G TAL AA C GHA+VV L+D GA++
Sbjct: 533 IAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEV 592
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+++GMTPL AA VV++L
Sbjct: 593 DHCDKDGMTPLLVAAYEGHVDVVDLL 618
Score = 93.9 bits (223), Expect = 2e-18
Identities = 62/161 (38%), Positives = 84/161 (52%), Gaps = 6/161 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF-----EGRLDIVKYLV 158
EG TAL A+ GH IV+ L+ GA+VNH T L A +G +V L+
Sbjct: 527 EGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLI 586
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
GA++ +K T L++AAY+G++DVV LL+ GA VD G T L AA GHA+
Sbjct: 587 DRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHAS 646
Query: 219 VVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
VV +LL GA + + G T L A+ + VV L R
Sbjct: 647 VVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDR 687
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/153 (31%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G L+ + L + + ++ GA+V + T L +C++G +++V+ L+ + AD
Sbjct: 796 DGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHAD 855
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ A+ + L AA++G++ VVQ L++ GA VD GATAL AA+ GH VV L
Sbjct: 856 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 915
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
L+HGA ++ G T ++ AA+ + ++++L
Sbjct: 916 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 948
Score = 88.2 bits (209), Expect = 8e-17
Identities = 54/149 (36%), Positives = 76/149 (51%), Gaps = 1/149 (0%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL + GH ++V L+ GA+V+H + TPL A +EG +D+V L+ GAD+
Sbjct: 569 ALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHT 628
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L+ AA G+ VV LL GA VD G T L A+ G+ VV +LLD G
Sbjct: 629 DNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 688
Query: 228 A-KMLTNENGMTPLQCAAERARASVVEIL 255
+ ++ G TPL AA + E L
Sbjct: 689 LDENHRDDAGWTPLHMAAFEGHRLICEAL 717
Score = 87.8 bits (208), Expect = 1e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL + GH+ +V+ L+ ADVN A + L++A ++G + +V+ L+ HGA
Sbjct: 829 EGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAV 888
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T L IAA +G++DVVQ LL+ GA + G TA+ AA+ GH+ ++ L
Sbjct: 889 VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 948
Query: 224 LDHGAKMLTNENGMTP 239
+GA L NG +P
Sbjct: 949 EKYGASSL---NGCSP 961
Score = 87.4 bits (207), Expect = 1e-16
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 15/204 (7%)
Query: 28 RDGMSLTLYALLYEKKTDEIDDLLN--IDVC-SDGVKCTPLITAARHGREGAVRILLEKF 84
+DGM+ L A YE D +D LL DV +D TPL+ AA G V LL
Sbjct: 597 KDGMTPLLVAA-YEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLF-- 653
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D EG T L AS G++ +V+ L+ G D NH TPL
Sbjct: 654 ---------WGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHM 704
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A FEG I + L+ GA ++ + ++A+ +G+ D VQ LL++ + +D R G
Sbjct: 705 AAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDG 764
Query: 205 ATALHFAAECGHAAVVCSLLDHGA 228
AL AA GH +V L HGA
Sbjct: 765 RNALRVAALEGHRDIVELLFSHGA 788
Score = 85.8 bits (203), Expect = 4e-16
Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH+ +V L++ GADV+H TPL AA G +V L+ GA
Sbjct: 598 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 657
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + T L IA+ +G ++VV+ LLD G + R G T LH AA GH + +L
Sbjct: 658 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 717
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEIL 255
++ GA+ TNE +G P A++ V+IL
Sbjct: 718 IEQGAR--TNEIDNDGRIPFILASQEGHYDCVQIL 750
Score = 78.6 bits (185), Expect = 7e-14
Identities = 71/232 (30%), Positives = 110/232 (47%), Gaps = 23/232 (9%)
Query: 26 AARDGMSLTLYALLYE-KKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKF 84
AA +G L AL+ + +T+EID+ DG P I A++ G V+ILLE
Sbjct: 705 AAFEGHRLICEALIEQGARTNEIDN--------DGR--IPFILASQEGHYDCVQILLEN- 753
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D+ +G AL A+ GH IV+ L GADVN L
Sbjct: 754 ----------KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI 803
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
E +L + +Y + +GA++ ++ T L ++ ++G++++VQ L+ A V+
Sbjct: 804 LALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEK 863
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+AL AA GH VV L++HGA + T G T L AA+ VV++L
Sbjct: 864 RSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 915
Score = 72.9 bits (171), Expect = 3e-12
Identities = 56/165 (33%), Positives = 84/165 (50%), Gaps = 4/165 (2%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
+++ LVKAGA VN S +R A R D ++ L+ +GA +++ + T L AA
Sbjct: 347 VLQLLVKAGAHVNSEDDRTSCIVRQAL--EREDSIRTLLDNGASVNQCDSNGRTLLANAA 404
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
Y G LDVV L+ GA ++ G T L AA GH VV L+ GA + T+++G T
Sbjct: 405 YSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWT 464
Query: 239 PLQCAAERARASVVE-ILAARPEVTRAEAIEAYELLGASFANDKE 282
L+ AA VV +L A +V A+A L A++ ++
Sbjct: 465 ALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHED 509
Score = 68.1 bits (159), Expect = 9e-11
Identities = 60/211 (28%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Query: 47 IDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEG 105
ID +D C DG+ TPL+ AA G V +LLE G D G
Sbjct: 586 IDRGAEVDHCDKDGM--TPLLVAAYEGHVDVVDLLLE-----------GGADVDHTDNNG 632
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
T L A+ GH ++V L+ GA V+ T L A +G +++V+ L+ G D +
Sbjct: 633 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 692
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T L +AA++G+ + + L++ GAR ++ G A++ GH V LL+
Sbjct: 693 HRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 752
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + + +G L+ AA +VE+L
Sbjct: 753 NKSNIDQRGYDGRNALRVAALEGHRDIVELL 783
Score = 60.5 bits (140), Expect = 2e-08
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 1/154 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH I + L++ GA N P A EG D V+ L+ + ++I
Sbjct: 698 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 757
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ L +AA +G+ D+V+ L GA V+ + G L+ A + L
Sbjct: 758 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 817
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
++GA + ++ G T L + + +V++L A
Sbjct: 818 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIA 851
Score = 40.7 bits (91), Expect = 0.016
Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
LLD GA+V+ D++ RT L VA + + + VV L+ RGA VD D D
Sbjct: 547 LLDHGAEVNHEDVDGRTALSVAALCVPAS--------KGHASVVSLLIDRGAEVDHCDKD 598
Query: 603 GITPLVAS 610
G+TPL+ +
Sbjct: 599 GMTPLLVA 606
Score = 36.3 bits (80), Expect = 0.35
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LL+D GA+VD D + TPL VA +Y E VV LL GA VD D
Sbjct: 584 LLIDRGAEVDHCDKDGMTPLLVA--AY-----------EGHVDVVDLLLEGGADVDHTDN 630
Query: 602 DGITPLVASIGGPAESLVRSAL 623
+G TPL+A+ S+V + L
Sbjct: 631 NGRTPLLAAASMGHASVVNTLL 652
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 113 bits (273), Expect = 1e-24
Identities = 96/266 (36%), Positives = 136/266 (51%), Gaps = 31/266 (11%)
Query: 1 MEREDNDRLVL-----FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDV 55
+ERED+ R +L N+ ++ R + AA G SL + LL + D L I+
Sbjct: 182 LEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSG-SLDVVNLLVSRGAD-----LEIE- 234
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
D TPL AAR G V L+ C + +G TAL A+
Sbjct: 235 --DAHGHTPLTLAARQGHTKVVNCLIG------C-----GANINHTDQDGWTALRSAAWG 281
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH +V L+ AG V+ A T LRAA + G DIV L++HGA+++KA+ T L
Sbjct: 282 GHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTAL 341
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC-----GHAAVVCSLLDHGAKM 230
+ AAY G+ ++V+ LLD GA V+ + G TAL AA C GHA+VV L+D GA++
Sbjct: 342 IAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEV 401
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+++GMTPL AA VV++L
Sbjct: 402 DHCDKDGMTPLLVAAYEGHVDVVDLL 427
Score = 93.9 bits (223), Expect = 2e-18
Identities = 62/161 (38%), Positives = 84/161 (52%), Gaps = 6/161 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF-----EGRLDIVKYLV 158
EG TAL A+ GH IV+ L+ GA+VNH T L A +G +V L+
Sbjct: 336 EGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLI 395
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
GA++ +K T L++AAY+G++DVV LL+ GA VD G T L AA GHA+
Sbjct: 396 DRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHAS 455
Query: 219 VVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
VV +LL GA + + G T L A+ + VV L R
Sbjct: 456 VVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDR 496
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/153 (31%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G L+ + L + + ++ GA+V + T L +C++G +++V+ L+ + AD
Sbjct: 605 DGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHAD 664
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ A+ + L AA++G++ VVQ L++ GA VD GATAL AA+ GH VV L
Sbjct: 665 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 724
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
L+HGA ++ G T ++ AA+ + ++++L
Sbjct: 725 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 757
Score = 88.2 bits (209), Expect = 8e-17
Identities = 54/149 (36%), Positives = 76/149 (51%), Gaps = 1/149 (0%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL + GH ++V L+ GA+V+H + TPL A +EG +D+V L+ GAD+
Sbjct: 378 ALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHT 437
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L+ AA G+ VV LL GA VD G T L A+ G+ VV +LLD G
Sbjct: 438 DNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 497
Query: 228 A-KMLTNENGMTPLQCAAERARASVVEIL 255
+ ++ G TPL AA + E L
Sbjct: 498 LDENHRDDAGWTPLHMAAFEGHRLICEAL 526
Score = 87.8 bits (208), Expect = 1e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL + GH+ +V+ L+ ADVN A + L++A ++G + +V+ L+ HGA
Sbjct: 638 EGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAV 697
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T L IAA +G++DVVQ LL+ GA + G TA+ AA+ GH+ ++ L
Sbjct: 698 VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 757
Query: 224 LDHGAKMLTNENGMTP 239
+GA L NG +P
Sbjct: 758 EKYGASSL---NGCSP 770
Score = 87.4 bits (207), Expect = 1e-16
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 15/204 (7%)
Query: 28 RDGMSLTLYALLYEKKTDEIDDLLN--IDVC-SDGVKCTPLITAARHGREGAVRILLEKF 84
+DGM+ L A YE D +D LL DV +D TPL+ AA G V LL
Sbjct: 406 KDGMTPLLVAA-YEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLF-- 462
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D EG T L AS G++ +V+ L+ G D NH TPL
Sbjct: 463 ---------WGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHM 513
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A FEG I + L+ GA ++ + ++A+ +G+ D VQ LL++ + +D R G
Sbjct: 514 AAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDG 573
Query: 205 ATALHFAAECGHAAVVCSLLDHGA 228
AL AA GH +V L HGA
Sbjct: 574 RNALRVAALEGHRDIVELLFSHGA 597
Score = 85.8 bits (203), Expect = 4e-16
Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH+ +V L++ GADV+H TPL AA G +V L+ GA
Sbjct: 407 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 466
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + T L IA+ +G ++VV+ LLD G + R G T LH AA GH + +L
Sbjct: 467 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 526
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEIL 255
++ GA+ TNE +G P A++ V+IL
Sbjct: 527 IEQGAR--TNEIDNDGRIPFILASQEGHYDCVQIL 559
Score = 78.6 bits (185), Expect = 7e-14
Identities = 71/232 (30%), Positives = 110/232 (47%), Gaps = 23/232 (9%)
Query: 26 AARDGMSLTLYALLYE-KKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKF 84
AA +G L AL+ + +T+EID+ DG P I A++ G V+ILLE
Sbjct: 514 AAFEGHRLICEALIEQGARTNEIDN--------DGR--IPFILASQEGHYDCVQILLEN- 562
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D+ +G AL A+ GH IV+ L GADVN L
Sbjct: 563 ----------KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI 612
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
E +L + +Y + +GA++ ++ T L ++ ++G++++VQ L+ A V+
Sbjct: 613 LALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEK 672
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+AL AA GH VV L++HGA + T G T L AA+ VV++L
Sbjct: 673 RSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 724
Score = 72.5 bits (170), Expect = 4e-12
Identities = 56/165 (33%), Positives = 84/165 (50%), Gaps = 4/165 (2%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
+++ LVKAGA VN S +R A R D ++ L+ +GA +++ + T L AA
Sbjct: 156 VLQLLVKAGAHVNSEDDRTSCIVRQAL--EREDSIRTLLDNGASVNQCDSNGRTLLANAA 213
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
Y G LDVV L+ GA ++ G T L AA GH VV L+ GA + T+++G T
Sbjct: 214 YSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWT 273
Query: 239 PLQCAAERARASVVE-ILAARPEVTRAEAIEAYELLGASFANDKE 282
L+ AA VV +L A +V A+A L A++ ++
Sbjct: 274 ALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHED 318
Score = 68.1 bits (159), Expect = 9e-11
Identities = 60/211 (28%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Query: 47 IDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEG 105
ID +D C DG+ TPL+ AA G V +LLE G D G
Sbjct: 395 IDRGAEVDHCDKDGM--TPLLVAAYEGHVDVVDLLLE-----------GGADVDHTDNNG 441
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
T L A+ GH ++V L+ GA V+ T L A +G +++V+ L+ G D +
Sbjct: 442 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 501
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T L +AA++G+ + + L++ GAR ++ G A++ GH V LL+
Sbjct: 502 HRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 561
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + + +G L+ AA +VE+L
Sbjct: 562 NKSNIDQRGYDGRNALRVAALEGHRDIVELL 592
Score = 60.5 bits (140), Expect = 2e-08
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 1/154 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH I + L++ GA N P A EG D V+ L+ + ++I
Sbjct: 507 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 566
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ L +AA +G+ D+V+ L GA V+ + G L+ A + L
Sbjct: 567 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 626
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
++GA + ++ G T L + + +V++L A
Sbjct: 627 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIA 660
Score = 40.7 bits (91), Expect = 0.016
Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
LLD GA+V+ D++ RT L VA + + + VV L+ RGA VD D D
Sbjct: 356 LLDHGAEVNHEDVDGRTALSVAALCVPAS--------KGHASVVSLLIDRGAEVDHCDKD 407
Query: 603 GITPLVAS 610
G+TPL+ +
Sbjct: 408 GMTPLLVA 415
Score = 36.3 bits (80), Expect = 0.35
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LL+D GA+VD D + TPL VA +Y E VV LL GA VD D
Sbjct: 393 LLIDRGAEVDHCDKDGMTPLLVA--AY-----------EGHVDVVDLLLEGGADVDHTDN 439
Query: 602 DGITPLVASIGGPAESLVRSAL 623
+G TPL+A+ S+V + L
Sbjct: 440 NGRTPLLAAASMGHASVVNTLL 461
>AK025265-1|BAB15096.1| 300|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21612 fis, clone COL07355. ).
Length = 300
Score = 111 bits (268), Expect = 6e-24
Identities = 94/329 (28%), Positives = 156/329 (47%), Gaps = 41/329 (12%)
Query: 341 LHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLALWRHALHLRQQN----QV 396
+ M+ L +RER+LG + PD + I +RGAV+AD F RC+ LW++AL ++Q N
Sbjct: 1 MRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSP 60
Query: 397 SVVKDLLRFAQVFSQMIH------IGIELPLAQVCYVLEACAEELRRGMKRLLKPNPQHD 450
LL FA++FS M+ +G + + +L E+ R +K+ P D
Sbjct: 61 MTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCP---AD 117
Query: 451 PDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQ 510
P L + + L+L+ LLE C + R F R ++
Sbjct: 118 PLQL----NKALSIILHLIC----LLE-KVPCTLEQDHFKKQTIYR--FLKLHPRGKNNF 166
Query: 511 TLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQL 570
+ LHLA D+NT + VC+FP + + +L++CGADV+ D + +PLH+A ++
Sbjct: 167 SPLHLAVDKNTTCVGRY--PVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALN--- 221
Query: 571 TSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPL-VASIGGPAESLVRSALRPRLSC 629
N ++ L+ GAH DA +L T + A++L++ L C
Sbjct: 222 --------NHP--DIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQC 271
Query: 630 ISASVLALHRVRYRPSQVPRDLHAFLIMH 658
++A V+ HR+ Y+ +P L F+ +H
Sbjct: 272 LAARVIVNHRIYYK-GHIPEKLETFVSLH 299
Score = 36.3 bits (80), Expect = 0.35
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 15/98 (15%)
Query: 151 LDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHF 210
L + L+ GAD++ + +N+ L IAA + D++ L+ SGA HF
Sbjct: 191 LQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGA-------------HF 237
Query: 211 AAECGHAAVVCSLLDHG--AKMLTNENGMTPLQCAAER 246
A H LLD AK L T LQC A R
Sbjct: 238 DATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAAR 275
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
L + L++ GADVN ++PL A DI+ L++ GA N + T
Sbjct: 191 LQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQT 246
>AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat
containing protein protein.
Length = 1101
Score = 102 bits (244), Expect = 5e-21
Identities = 63/152 (41%), Positives = 86/152 (56%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+G G L + + L++ GA V R + PL + +G IV L+ HGAD+
Sbjct: 135 GETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADV 194
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ A+K T LM+AA +G+L V FLL GA + G TAL +A GH +VV SL+
Sbjct: 195 NMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLV 254
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
D+GA ++NG TPL AA A VV+ L
Sbjct: 255 DNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 286
Score = 92.3 bits (219), Expect = 5e-18
Identities = 63/152 (41%), Positives = 77/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA L+ GH IV L+ GADVN A + TPL A EG L V +L+ GA I
Sbjct: 168 GAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASI 227
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L A KG+L VV+ L+D+GA D G T L AA G A VV L+
Sbjct: 228 ALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLV 287
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + + +GM PL A SVV L
Sbjct: 288 DHGAMIEHVDYSGMRPLDRAVGCPNTSVVVTL 319
Score = 75.4 bits (177), Expect = 6e-13
Identities = 45/121 (37%), Positives = 64/121 (52%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GHL V L+ GA + + T L AC +G L +V+ LV +GA
Sbjct: 200 QGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAA 259
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
A+K T L +AA+ G +VVQFL+D GA ++ G L A C + +VV +L
Sbjct: 260 TDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCPNTSVVVTL 319
Query: 224 L 224
L
Sbjct: 320 L 320
Score = 61.7 bits (143), Expect = 8e-09
Identities = 59/189 (31%), Positives = 86/189 (45%), Gaps = 18/189 (9%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVK-----AGAD--VNHATRTVST 140
V L + K D G AL A+ GHL +VK L++ AG V + +
Sbjct: 35 VVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQ 94
Query: 141 PLRAACFEGRLDIVKYLV----RHGADIHKA--NKYNN----TCLMIAAYKGYLDVVQFL 190
L AA G +IV YL+ + ++ +A N +++ T L AA +G L+V + L
Sbjct: 95 ALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLL 154
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARA 249
L+ GA V GA L GH +V LL HGA + + ++ G TPL AA
Sbjct: 155 LEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHL 214
Query: 250 SVVEILAAR 258
V+ L A+
Sbjct: 215 GTVDFLLAQ 223
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/186 (29%), Positives = 80/186 (43%), Gaps = 18/186 (9%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E D G T L A+ AG+L+IV L K A V+H + L A
Sbjct: 2 VALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAAL 61
Query: 148 EGRLDIVKYLVR-------HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
G L++VK+L++ + K + L+ AA GY ++V +LLD + ++
Sbjct: 62 RGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEE 121
Query: 201 ----------ALCGATALHFAAECGHAAVVCSLLDHGAKML-TNENGMTPLQCAAERARA 249
+L G TAL AA G V LL+ GA + N G PL +
Sbjct: 122 VERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHW 181
Query: 250 SVVEIL 255
+V++L
Sbjct: 182 QIVDLL 187
Score = 45.2 bits (102), Expect = 7e-04
Identities = 36/113 (31%), Positives = 59/113 (52%), Gaps = 7/113 (6%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
+V L++ GA+V+ ++ + TPL A G L IV L + A + +K L+ AA
Sbjct: 1 MVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAA 60
Query: 180 YKGYLDVVQFLLD-----SGAR--VDDRALCGATALHFAAECGHAAVVCSLLD 225
+G+L+VV+FL+ +G + V ++ AL AA G+ +V LLD
Sbjct: 61 LRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLD 113
Score = 40.7 bits (91), Expect = 0.016
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 13/86 (15%)
Query: 541 RLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMD 600
R L+D GA D AD N RTPL +A Y +A VV L+ GA ++ +D
Sbjct: 251 RSLVDNGAATDHADKNGRTPLDLAAF-----------YGDA--EVVQFLVDHGAMIEHVD 297
Query: 601 LDGITPLVASIGGPAESLVRSALRPR 626
G+ PL ++G P S+V + L+ R
Sbjct: 298 YSGMRPLDRAVGCPNTSVVVTLLKKR 323
Score = 39.5 bits (88), Expect = 0.037
Identities = 30/95 (31%), Positives = 44/95 (46%)
Query: 153 IVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
+V L+ GA++ +++ T L AA GYL +V L A+VD G AL AA
Sbjct: 1 MVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAA 60
Query: 213 ECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERA 247
GH VV L+ M + G+ A ++A
Sbjct: 61 LRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQA 95
Score = 35.1 bits (77), Expect = 0.80
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 13/66 (19%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LLL GADV+ AD RTPL +A +E G V LL++GA + MD
Sbjct: 186 LLLTHGADVNMADKQGRTPLMMAA-------------SEGHLGTVDFLLAQGASIALMDK 232
Query: 602 DGITPL 607
+G+T L
Sbjct: 233 EGLTAL 238
>AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein.
Length = 1864
Score = 102 bits (244), Expect = 5e-21
Identities = 63/152 (41%), Positives = 86/152 (56%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+G G L + + L++ GA V R + PL + +G IV L+ HGAD+
Sbjct: 908 GETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADV 967
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ A+K T LM+AA +G+L V FLL GA + G TAL +A GH +VV SL+
Sbjct: 968 NMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLV 1027
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
D+GA ++NG TPL AA A VV+ L
Sbjct: 1028 DNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1059
Score = 92.3 bits (219), Expect = 5e-18
Identities = 63/152 (41%), Positives = 77/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA L+ GH IV L+ GADVN A + TPL A EG L V +L+ GA I
Sbjct: 941 GAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASI 1000
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L A KG+L VV+ L+D+GA D G T L AA G A VV L+
Sbjct: 1001 ALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLV 1060
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + + +GM PL A SVV L
Sbjct: 1061 DHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTL 1092
Score = 81.0 bits (191), Expect = 1e-14
Identities = 48/127 (37%), Positives = 68/127 (53%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GHL V L+ GA + + T L AC +G L +V+ LV +GA
Sbjct: 973 QGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAA 1032
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
A+K T L +AA+ G +VVQFL+D GA ++ G L A C + +VV +L
Sbjct: 1033 TDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTL 1092
Query: 224 LDHGAKM 230
L GAK+
Sbjct: 1093 LKKGAKI 1099
Score = 61.7 bits (143), Expect = 8e-09
Identities = 59/189 (31%), Positives = 86/189 (45%), Gaps = 18/189 (9%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVK-----AGAD--VNHATRTVST 140
V L + K D G AL A+ GHL +VK L++ AG V + +
Sbjct: 808 VVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQ 867
Query: 141 PLRAACFEGRLDIVKYLV----RHGADIHKA--NKYNN----TCLMIAAYKGYLDVVQFL 190
L AA G +IV YL+ + ++ +A N +++ T L AA +G L+V + L
Sbjct: 868 ALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLL 927
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARA 249
L+ GA V GA L GH +V LL HGA + + ++ G TPL AA
Sbjct: 928 LEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHL 987
Query: 250 SVVEILAAR 258
V+ L A+
Sbjct: 988 GTVDFLLAQ 996
Score = 59.7 bits (138), Expect = 3e-08
Identities = 54/186 (29%), Positives = 80/186 (43%), Gaps = 18/186 (9%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E D G T L A+ AG+L+IV L K A V+H + L A
Sbjct: 775 VALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAAL 834
Query: 148 EGRLDIVKYLVR-------HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
G L++VK+L++ + K + L+ AA GY ++V +LLD + ++
Sbjct: 835 RGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQALIAAASMGYTEIVSYLLDLPEKDEEE 894
Query: 201 ----------ALCGATALHFAAECGHAAVVCSLLDHGAKML-TNENGMTPLQCAAERARA 249
+L G TAL AA G V LL+ GA + N G PL +
Sbjct: 895 VERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHW 954
Query: 250 SVVEIL 255
+V++L
Sbjct: 955 QIVDLL 960
Score = 51.6 bits (118), Expect = 9e-06
Identities = 41/137 (29%), Positives = 68/137 (49%), Gaps = 7/137 (5%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
+ + V+ A L S G+ +V L++ GA+V+ ++ + TPL A G L IV
Sbjct: 750 INYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVV 809
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD-----SGAR--VDDRALCGATAL 208
L + A + +K L+ AA +G+L+VV+FL+ +G + V ++ AL
Sbjct: 810 LLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQQGVFKKSHAIQQAL 869
Query: 209 HFAAECGHAAVVCSLLD 225
AA G+ +V LLD
Sbjct: 870 IAAASMGYTEIVSYLLD 886
Score = 48.4 bits (110), Expect = 8e-05
Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 2/133 (1%)
Query: 117 HLAIVKRLVKAGADVNHATRTVSTP--LRAACFEGRLDIVKYLVRHGADIHKANKYNNTC 174
++ + + L+ GA++N+ T ++ L G ++V L+ GA++ +++ T
Sbjct: 736 NIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTP 795
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE 234
L AA GYL +V L A+VD G AL AA GH VV L+ M +
Sbjct: 796 LGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQQ 855
Query: 235 NGMTPLQCAAERA 247
G+ A ++A
Sbjct: 856 QGVFKKSHAIQQA 868
Score = 35.5 bits (78), Expect = 0.61
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Query: 180 YKGYLDVVQFLLDSGARVDDRA--LCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENG 236
Y + V + L+ GA ++ R L A L + G+ +V LL+ GA + ++E+G
Sbjct: 733 YTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESG 792
Query: 237 MTPLQCAAERARASVVEILAAR 258
+TPL AA S+V +L +
Sbjct: 793 LTPLGYAAAAGYLSIVVLLCKK 814
Score = 35.5 bits (78), Expect = 0.61
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 13/84 (15%)
Query: 541 RLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMD 600
R L+D GA D AD N RTPL +A Y +A VV L+ GA ++ +D
Sbjct: 1024 RSLVDNGAATDHADKNGRTPLDLAAF-----------YGDA--EVVQFLVDHGAMIEHVD 1070
Query: 601 LDGITPLVASIGGPAESLVRSALR 624
G+ PL ++G S+V + L+
Sbjct: 1071 YSGMRPLDRAVGCRNTSVVVTLLK 1094
Score = 35.1 bits (77), Expect = 0.80
Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 13/66 (19%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LLL GADV+ AD RTPL +A +E G V LL++GA + MD
Sbjct: 959 LLLTHGADVNMADKQGRTPLMMAA-------------SEGHLGTVDFLLAQGASIALMDK 1005
Query: 602 DGITPL 607
+G+T L
Sbjct: 1006 EGLTAL 1011
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 54 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 113
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 114 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 173
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 174 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 205
Score = 89.0 bits (211), Expect = 5e-17
Identities = 51/154 (33%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ L+K GA + T + TP+ A F G ++IV L+ HGA
Sbjct: 19 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 78
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ N T L +AA G +VV++L+ GA+V+ +A T LH +A G A +V
Sbjct: 79 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 138
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL GA +G TPL +A V L
Sbjct: 139 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 172
Score = 86.6 bits (205), Expect = 2e-16
Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + I L++ GAD N TR + A EG +D+V L+ A++
Sbjct: 252 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 311
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +NK T L +AA + ++V + L++ GA VD + G T LH G+ +V LL
Sbjct: 312 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 371
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H AK+ +NG TPL AA++ ++ +L
Sbjct: 372 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 403
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 85 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 144
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 145 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 204
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 205 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 253
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/222 (30%), Positives = 102/222 (45%), Gaps = 14/222 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 155 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 203
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 204 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 263
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+D+ LL+ GA + G ++H AA+ GH +V LL A + L+N++G+TPL
Sbjct: 264 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH 323
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 324 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 365
Score = 79.8 bits (188), Expect = 3e-14
Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 5/162 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+VN + ++ TPL A E R+++ + LV GA
Sbjct: 284 QGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH 343
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 344 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 403
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 404 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 443
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 122 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 170
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 171 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 230
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 231 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 290
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 291 LAAQEGHVDMVSLLLGR 307
Score = 42.7 bits (96), Expect = 0.004
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+ AA
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 249 ASVVEIL---AARPEVTRAEAIEAYELLGAS 276
++V L A P T A + S
Sbjct: 67 VNIVSQLMHHGASPNTTNVRGETALHMAARS 97
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 433 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 552
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 553 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 93.1 bits (221), Expect = 3e-18
Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 23/237 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRP----------PVCLETEG------------TVKFDE 100
TPL AR G E V +LL++ P P+ + T+G V D+
Sbjct: 303 TPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDD 362
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
+ TAL A+ GH + K L+ A+ N TPL AC + R+ +++ L++H
Sbjct: 363 VTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH 422
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVV 220
GA I + T + +AA+ G++++V L+ GA + + G TALH AA G A VV
Sbjct: 423 GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV 482
Query: 221 CSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
L+ GA++ ++ TPL +A +A +V+ L + A Y L S
Sbjct: 483 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLS 539
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AGHL +K G D+N + L A EG +++V L++ A++ A K
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KM 230
NT L IA+ G +VV+ L+ +GA V+ ++ G T L+ AA+ H VV LLD+GA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
L E+G TPL A ++ VV +L
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLL 192
Score = 89.4 bits (212), Expect = 4e-17
Identities = 63/203 (31%), Positives = 94/203 (46%), Gaps = 14/203 (6%)
Query: 54 DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCAS 113
DV +D + T L AA G ++LL+K P + + G T L A
Sbjct: 362 DVTNDYL--TALHVAAHCGHYKVAKVLLDKKANP-----------NAKALNGFTPLHIAC 408
Query: 114 GAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
+ +++ L+K GA + T + TP+ A F G ++IV L+ HGA + N T
Sbjct: 409 KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGET 468
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLT 232
L +AA G +VV++L+ GA+V+ +A T LH +A G A +V LL GA
Sbjct: 469 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 233 NENGMTPLQCAAERARASVVEIL 255
+G TPL +A V L
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFL 551
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 15/218 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ K D +G T L C + +GH +V+
Sbjct: 270 TPLHVASKRGNANMVKLLLDR-----------GAKIDAKTRDGLTPLHCGARSGHEQVVE 318
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ A + T+ +PL A L+ V+ L++H + T L +AA+ G
Sbjct: 319 MLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG 378
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+
Sbjct: 379 HYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIH 438
Query: 242 CAAERARASVVEIL---AARPEVTRAEAIEAYELLGAS 276
AA ++V L A P T A + S
Sbjct: 439 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS 476
Score = 86.6 bits (205), Expect = 2e-16
Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + I L++ GAD N TR + A EG +D+V L+ A++
Sbjct: 631 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +NK T L +AA + ++V + L++ GA VD + G T LH G+ +V LL
Sbjct: 691 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 750
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H AK+ +NG TPL AA++ ++ +L
Sbjct: 751 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 632
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/222 (30%), Positives = 102/222 (45%), Gaps = 14/222 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 534 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 582
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+D+ LL+ GA + G ++H AA+ GH +V LL A + L+N++G+TPL
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH 702
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 703 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 744
Score = 81.0 bits (191), Expect = 1e-14
Identities = 47/125 (37%), Positives = 73/125 (58%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL AS GH+ +V L++ A+V+ AT+ +T L A G+ ++VK LV +GA++
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + +L+VV+FLLD+GA G T L A + GH VV LL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 225 DHGAK 229
++ K
Sbjct: 194 ENDTK 198
Score = 79.8 bits (188), Expect = 3e-14
Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 5/162 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+VN + ++ TPL A E R+++ + LV GA
Sbjct: 663 QGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH 722
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 723 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 783 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 822
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 21/221 (9%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
EK D I + ++I++C+ +G+ L + +EG V ++ E L+ E V D
Sbjct: 55 EKALDYIKNGVDINICNQNGLNALHLAS-----KEGHVEVVSE------LLQREANV--D 101
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL AS AG +VK LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA A + T L +A +G+ VV LL++ D + ALH AA
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKA 217
Query: 220 VCSLL--DHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
LL D+ A + +++G TPL AA +V +L R
Sbjct: 218 AALLLQNDNNAD-VESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/194 (28%), Positives = 94/194 (48%), Gaps = 16/194 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A + G + V +LLE +T+G V+ AL A+
Sbjct: 175 TPLAVALQQGHDQVVSLLLEN-------DTKGKVRLP--------ALHIAARKDDTKAAA 219
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ + + +++ TPL A G +++ L+ A + + + T L +A+ +G
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQ 241
++V+ LLD GA++D + G T LH A GH VV LLD A +L+ +NG++PL
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 242 CAAERARASVVEIL 255
A + + V++L
Sbjct: 340 MATQGDHLNCVQLL 353
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 549
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 670 LAAQEGHVDMVSLLLGR 686
Score = 66.5 bits (155), Expect = 3e-10
Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G++ + L+ A V+ R TPL A G ++VK L+ GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L A G+ VV+ LLD A + + G + LH A + H V LL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
H + +TN+ +T L AA V ++L + A+A+ +
Sbjct: 355 QHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Score = 39.5 bits (88), Expect = 0.037
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
N + AA G+L+ + +G ++ G ALH A++ GH VV LL A +
Sbjct: 42 NASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVD 101
Query: 231 LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+ G T L A+ +A VV++L A++
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 433 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 552
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 553 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 93.1 bits (221), Expect = 3e-18
Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 23/237 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRP----------PVCLETEG------------TVKFDE 100
TPL AR G E V +LL++ P P+ + T+G V D+
Sbjct: 303 TPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDD 362
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
+ TAL A+ GH + K L+ A+ N TPL AC + R+ +++ L++H
Sbjct: 363 VTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH 422
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVV 220
GA I + T + +AA+ G++++V L+ GA + + G TALH AA G A VV
Sbjct: 423 GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV 482
Query: 221 CSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
L+ GA++ ++ TPL +A +A +V+ L + A Y L S
Sbjct: 483 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLS 539
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AGHL +K G D+N + L A EG +++V L++ A++ A K
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KM 230
NT L IA+ G +VV+ L+ +GA V+ ++ G T L+ AA+ H VV LLD+GA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
L E+G TPL A ++ VV +L
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLL 192
Score = 89.4 bits (212), Expect = 4e-17
Identities = 63/203 (31%), Positives = 94/203 (46%), Gaps = 14/203 (6%)
Query: 54 DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCAS 113
DV +D + T L AA G ++LL+K P + + G T L A
Sbjct: 362 DVTNDYL--TALHVAAHCGHYKVAKVLLDKKANP-----------NAKALNGFTPLHIAC 408
Query: 114 GAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
+ +++ L+K GA + T + TP+ A F G ++IV L+ HGA + N T
Sbjct: 409 KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGET 468
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLT 232
L +AA G +VV++L+ GA+V+ +A T LH +A G A +V LL GA
Sbjct: 469 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 233 NENGMTPLQCAAERARASVVEIL 255
+G TPL +A V L
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFL 551
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 15/218 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ K D +G T L C + +GH +V+
Sbjct: 270 TPLHVASKRGNANMVKLLLDR-----------GAKIDAKTRDGLTPLHCGARSGHEQVVE 318
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ A + T+ +PL A L+ V+ L++H + T L +AA+ G
Sbjct: 319 MLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG 378
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+
Sbjct: 379 HYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIH 438
Query: 242 CAAERARASVVEIL---AARPEVTRAEAIEAYELLGAS 276
AA ++V L A P T A + S
Sbjct: 439 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS 476
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 632
Score = 81.0 bits (191), Expect = 1e-14
Identities = 47/125 (37%), Positives = 73/125 (58%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL AS GH+ +V L++ A+V+ AT+ +T L A G+ ++VK LV +GA++
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + +L+VV+FLLD+GA G T L A + GH VV LL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 225 DHGAK 229
++ K
Sbjct: 194 ENDTK 198
Score = 78.2 bits (184), Expect = 9e-14
Identities = 67/221 (30%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 534 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 582
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQC 242
+D+ LL+ GA + G ++H AA+ GH +V LL A N +G+TPL
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA----NVSGLTPLHL 698
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 21/221 (9%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
EK D I + ++I++C+ +G+ L + +EG V ++ E L+ E V D
Sbjct: 55 EKALDYIKNGVDINICNQNGLNALHLAS-----KEGHVEVVSE------LLQREANV--D 101
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL AS AG +VK LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA A + T L +A +G+ VV LL++ D + ALH AA
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKA 217
Query: 220 VCSLL--DHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
LL D+ A + +++G TPL AA +V +L R
Sbjct: 218 AALLLQNDNNAD-VESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/194 (28%), Positives = 94/194 (48%), Gaps = 16/194 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A + G + V +LLE +T+G V+ AL A+
Sbjct: 175 TPLAVALQQGHDQVVSLLLEN-------DTKGKVRLP--------ALHIAARKDDTKAAA 219
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ + + +++ TPL A G +++ L+ A + + + T L +A+ +G
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQ 241
++V+ LLD GA++D + G T LH A GH VV LLD A +L+ +NG++PL
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 242 CAAERARASVVEIL 255
A + + V++L
Sbjct: 340 MATQGDHLNCVQLL 353
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 549
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 670 LAAQEGHVDMVSLLLGR 686
Score = 70.5 bits (165), Expect = 2e-11
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+V+ T PL A E R+++ + LV GA
Sbjct: 663 QGIASVHLAAQEGHVDMVSLLLGRNANVSGLT-----PLHLAAQEDRVNVAEVLVNQGAH 717
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 718 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 778 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 62/121 (51%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A+ + + + LV GA V+ T+ TPL C G + IV +L++H A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ K T L AA +G+ ++ LL + A ++ + G TAL A G+ +VV +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 223 L 223
L
Sbjct: 810 L 810
Score = 66.5 bits (155), Expect = 3e-10
Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G++ + L+ A V+ R TPL A G ++VK L+ GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L A G+ VV+ LLD A + + G + LH A + H V LL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
H + +TN+ +T L AA V ++L + A+A+ +
Sbjct: 355 QHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Score = 39.5 bits (88), Expect = 0.037
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
N + AA G+L+ + +G ++ G ALH A++ GH VV LL A +
Sbjct: 42 NASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVD 101
Query: 231 LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+ G T L A+ +A VV++L A++
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 48 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 108 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 167
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 168 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 199
Score = 89.0 bits (211), Expect = 5e-17
Identities = 51/154 (33%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ L+K GA + T + TP+ A F G ++IV L+ HGA
Sbjct: 13 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 72
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ N T L +AA G +VV++L+ GA+V+ +A T LH +A G A +V
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL GA +G TPL +A V L
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 79 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 198
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 199 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 247
Score = 78.2 bits (184), Expect = 9e-14
Identities = 67/221 (30%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 149 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 197
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 198 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 257
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQC 242
+D+ LL+ GA + G ++H AA+ GH +V LL A N +G+TPL
Sbjct: 258 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA----NVSGLTPLHL 313
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 314 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 354
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 116 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 164
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 165 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 284
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 285 LAAQEGHVDMVSLLLGR 301
Score = 70.5 bits (165), Expect = 2e-11
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+V+ T PL A E R+++ + LV GA
Sbjct: 278 QGIASVHLAAQEGHVDMVSLLLGRNANVSGLT-----PLHLAAQEDRVNVAEVLVNQGAH 332
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 333 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 393 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 432
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 62/121 (51%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A+ + + + LV GA V+ T+ TPL C G + IV +L++H A
Sbjct: 305 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 364
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ K T L AA +G+ ++ LL + A ++ + G TAL A G+ +VV +
Sbjct: 365 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 424
Query: 223 L 223
L
Sbjct: 425 L 425
Score = 42.7 bits (96), Expect = 0.004
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+ AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 249 ASVVEIL---AARPEVTRAEAIEAYELLGAS 276
++V L A P T A + S
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARS 91
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 433 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 552
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 553 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 93.1 bits (221), Expect = 3e-18
Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 23/237 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRP----------PVCLETEG------------TVKFDE 100
TPL AR G E V +LL++ P P+ + T+G V D+
Sbjct: 303 TPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDD 362
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
+ TAL A+ GH + K L+ A+ N TPL AC + R+ +++ L++H
Sbjct: 363 VTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH 422
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVV 220
GA I + T + +AA+ G++++V L+ GA + + G TALH AA G A VV
Sbjct: 423 GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV 482
Query: 221 CSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
L+ GA++ ++ TPL +A +A +V+ L + A Y L S
Sbjct: 483 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLS 539
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AGHL +K G D+N + L A EG +++V L++ A++ A K
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KM 230
NT L IA+ G +VV+ L+ +GA V+ ++ G T L+ AA+ H VV LLD+GA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
L E+G TPL A ++ VV +L
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLL 192
Score = 89.4 bits (212), Expect = 4e-17
Identities = 63/203 (31%), Positives = 94/203 (46%), Gaps = 14/203 (6%)
Query: 54 DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCAS 113
DV +D + T L AA G ++LL+K P + + G T L A
Sbjct: 362 DVTNDYL--TALHVAAHCGHYKVAKVLLDKKANP-----------NAKALNGFTPLHIAC 408
Query: 114 GAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
+ +++ L+K GA + T + TP+ A F G ++IV L+ HGA + N T
Sbjct: 409 KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGET 468
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLT 232
L +AA G +VV++L+ GA+V+ +A T LH +A G A +V LL GA
Sbjct: 469 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 233 NENGMTPLQCAAERARASVVEIL 255
+G TPL +A V L
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFL 551
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 15/218 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ K D +G T L C + +GH +V+
Sbjct: 270 TPLHVASKRGNANMVKLLLDR-----------GAKIDAKTRDGLTPLHCGARSGHEQVVE 318
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ A + T+ +PL A L+ V+ L++H + T L +AA+ G
Sbjct: 319 MLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG 378
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+
Sbjct: 379 HYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIH 438
Query: 242 CAAERARASVVEIL---AARPEVTRAEAIEAYELLGAS 276
AA ++V L A P T A + S
Sbjct: 439 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS 476
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 632
Score = 81.0 bits (191), Expect = 1e-14
Identities = 47/125 (37%), Positives = 73/125 (58%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL AS GH+ +V L++ A+V+ AT+ +T L A G+ ++VK LV +GA++
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + +L+VV+FLLD+GA G T L A + GH VV LL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 225 DHGAK 229
++ K
Sbjct: 194 ENDTK 198
Score = 78.2 bits (184), Expect = 9e-14
Identities = 67/221 (30%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 534 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 582
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQC 242
+D+ LL+ GA + G ++H AA+ GH +V LL A N +G+TPL
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA----NVSGLTPLHL 698
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 21/221 (9%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
EK D I + ++I++C+ +G+ L + +EG V ++ E L+ E V D
Sbjct: 55 EKALDYIKNGVDINICNQNGLNALHLAS-----KEGHVEVVSE------LLQREANV--D 101
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL AS AG +VK LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA A + T L +A +G+ VV LL++ D + ALH AA
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKA 217
Query: 220 VCSLL--DHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
LL D+ A + +++G TPL AA +V +L R
Sbjct: 218 AALLLQNDNNAD-VESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/194 (28%), Positives = 94/194 (48%), Gaps = 16/194 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A + G + V +LLE +T+G V+ AL A+
Sbjct: 175 TPLAVALQQGHDQVVSLLLEN-------DTKGKVRLP--------ALHIAARKDDTKAAA 219
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ + + +++ TPL A G +++ L+ A + + + T L +A+ +G
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQ 241
++V+ LLD GA++D + G T LH A GH VV LLD A +L+ +NG++PL
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 242 CAAERARASVVEIL 255
A + + V++L
Sbjct: 340 MATQGDHLNCVQLL 353
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 549
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 670 LAAQEGHVDMVSLLLGR 686
Score = 70.5 bits (165), Expect = 2e-11
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+V+ T PL A E R+++ + LV GA
Sbjct: 663 QGIASVHLAAQEGHVDMVSLLLGRNANVSGLT-----PLHLAAQEDRVNVAEVLVNQGAH 717
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 718 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 778 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 62/121 (51%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A+ + + + LV GA V+ T+ TPL C G + IV +L++H A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ K T L AA +G+ ++ LL + A ++ + G TAL A G+ +VV +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 223 L 223
L
Sbjct: 810 L 810
Score = 66.5 bits (155), Expect = 3e-10
Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G++ + L+ A V+ R TPL A G ++VK L+ GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L A G+ VV+ LLD A + + G + LH A + H V LL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
H + +TN+ +T L AA V ++L + A+A+ +
Sbjct: 355 QHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Score = 39.5 bits (88), Expect = 0.037
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
N + AA G+L+ + +G ++ G ALH A++ GH VV LL A +
Sbjct: 42 NASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVD 101
Query: 231 LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+ G T L A+ +A VV++L A++
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 48 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 108 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 167
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 168 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 199
Score = 89.0 bits (211), Expect = 5e-17
Identities = 51/154 (33%), Positives = 76/154 (49%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ L+K GA + T + TP+ A F G ++IV L+ HGA
Sbjct: 13 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 72
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ N T L +AA G +VV++L+ GA+V+ +A T LH +A G A +V
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL GA +G TPL +A V L
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 79 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 198
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 199 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 247
Score = 78.2 bits (184), Expect = 9e-14
Identities = 67/221 (30%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 149 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 197
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 198 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 257
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQC 242
+D+ LL+ GA + G ++H AA+ GH +V LL A N +G+TPL
Sbjct: 258 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA----NVSGLTPLHL 313
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 314 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 354
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 116 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 164
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 165 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 224
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 225 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 284
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 285 LAAQEGHVDMVSLLLGR 301
Score = 70.5 bits (165), Expect = 2e-11
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+V+ T PL A E R+++ + LV GA
Sbjct: 278 QGIASVHLAAQEGHVDMVSLLLGRNANVSGLT-----PLHLAAQEDRVNVAEVLVNQGAH 332
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 333 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 393 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 432
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 62/121 (51%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A+ + + + LV GA V+ T+ TPL C G + IV +L++H A
Sbjct: 305 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 364
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ K T L AA +G+ ++ LL + A ++ + G TAL A G+ +VV +
Sbjct: 365 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 424
Query: 223 L 223
L
Sbjct: 425 L 425
Score = 42.7 bits (96), Expect = 0.004
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+ AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 249 ASVVEIL---AARPEVTRAEAIEAYELLGAS 276
++V L A P T A + S
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARS 91
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 97.5 bits (232), Expect = 1e-19
Identities = 57/152 (37%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GH+ IV +L+ GA N T L A G+ ++V+YLV+ GA +
Sbjct: 433 GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + T L I+A G D+VQ LL GA + G T LH +A GH V LL
Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLL 552
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
DHGA + +T + G TPL AA+ + V +L
Sbjct: 553 DHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 93.1 bits (221), Expect = 3e-18
Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 23/237 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRP----------PVCLETEG------------TVKFDE 100
TPL AR G E V +LL++ P P+ + T+G V D+
Sbjct: 303 TPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDD 362
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
+ TAL A+ GH + K L+ A+ N TPL AC + R+ +++ L++H
Sbjct: 363 VTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKH 422
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVV 220
GA I + T + +AA+ G++++V L+ GA + + G TALH AA G A VV
Sbjct: 423 GASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV 482
Query: 221 CSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
L+ GA++ ++ TPL +A +A +V+ L + A Y L S
Sbjct: 483 RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLS 539
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AGHL +K G D+N + L A EG +++V L++ A++ A K
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KM 230
NT L IA+ G +VV+ L+ +GA V+ ++ G T L+ AA+ H VV LLD+GA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
L E+G TPL A ++ VV +L
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLL 192
Score = 89.4 bits (212), Expect = 4e-17
Identities = 63/203 (31%), Positives = 94/203 (46%), Gaps = 14/203 (6%)
Query: 54 DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCAS 113
DV +D + T L AA G ++LL+K P + + G T L A
Sbjct: 362 DVTNDYL--TALHVAAHCGHYKVAKVLLDKKANP-----------NAKALNGFTPLHIAC 408
Query: 114 GAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
+ +++ L+K GA + T + TP+ A F G ++IV L+ HGA + N T
Sbjct: 409 KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGET 468
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLT 232
L +AA G +VV++L+ GA+V+ +A T LH +A G A +V LL GA
Sbjct: 469 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 233 NENGMTPLQCAAERARASVVEIL 255
+G TPL +A V L
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFL 551
Score = 87.0 bits (206), Expect = 2e-16
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 15/218 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ K D +G T L C + +GH +V+
Sbjct: 270 TPLHVASKRGNANMVKLLLDR-----------GAKIDAKTRDGLTPLHCGARSGHEQVVE 318
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ A + T+ +PL A L+ V+ L++H + T L +AA+ G
Sbjct: 319 MLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG 378
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + +AL G T LH A + V+ LL HGA + E+G+TP+
Sbjct: 379 HYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIH 438
Query: 242 CAAERARASVVEIL---AARPEVTRAEAIEAYELLGAS 276
AA ++V L A P T A + S
Sbjct: 439 VAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARS 476
Score = 84.2 bits (199), Expect = 1e-15
Identities = 57/169 (33%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANL 583
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A ++G+TPL AA V +L + A A Y
Sbjct: 584 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 632
Score = 81.0 bits (191), Expect = 1e-14
Identities = 47/125 (37%), Positives = 73/125 (58%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL AS GH+ +V L++ A+V+ AT+ +T L A G+ ++VK LV +GA++
Sbjct: 74 GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + +L+VV+FLLD+GA G T L A + GH VV LL
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193
Query: 225 DHGAK 229
++ K
Sbjct: 194 ENDTK 198
Score = 78.2 bits (184), Expect = 9e-14
Identities = 67/221 (30%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 534 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 582
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 642
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQC 242
+D+ LL+ GA + G ++H AA+ GH +V LL A N +G+TPL
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA----NVSGLTPLHL 698
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 699 AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 21/221 (9%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
EK D I + ++I++C+ +G+ L + +EG V ++ E L+ E V D
Sbjct: 55 EKALDYIKNGVDINICNQNGLNALHLAS-----KEGHVEVVSE------LLQREANV--D 101
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL AS AG +VK LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA A + T L +A +G+ VV LL++ D + ALH AA
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKA 217
Query: 220 VCSLL--DHGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
LL D+ A + +++G TPL AA +V +L R
Sbjct: 218 AALLLQNDNNAD-VESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/194 (28%), Positives = 94/194 (48%), Gaps = 16/194 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A + G + V +LLE +T+G V+ AL A+
Sbjct: 175 TPLAVALQQGHDQVVSLLLEN-------DTKGKVRLP--------ALHIAARKDDTKAAA 219
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ + + +++ TPL A G +++ L+ A + + + T L +A+ +G
Sbjct: 220 LLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG 279
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQ 241
++V+ LLD GA++D + G T LH A GH VV LLD A +L+ +NG++PL
Sbjct: 280 NANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH 339
Query: 242 CAAERARASVVEIL 255
A + + V++L
Sbjct: 340 MATQGDHLNCVQLL 353
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 549
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 550 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 670 LAAQEGHVDMVSLLLGR 686
Score = 70.5 bits (165), Expect = 2e-11
Identities = 52/162 (32%), Positives = 78/162 (48%), Gaps = 10/162 (6%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+V+ T PL A E R+++ + LV GA
Sbjct: 663 QGIASVHLAAQEGHVDMVSLLLGRNANVSGLT-----PLHLAAQEDRVNVAEVLVNQGAH 717
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 718 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 778 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 817
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 62/121 (51%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A+ + + + LV GA V+ T+ TPL C G + IV +L++H A
Sbjct: 690 VSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 749
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ K T L AA +G+ ++ LL + A ++ + G TAL A G+ +VV +
Sbjct: 750 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDT 809
Query: 223 L 223
L
Sbjct: 810 L 810
Score = 66.5 bits (155), Expect = 3e-10
Identities = 49/168 (29%), Positives = 75/168 (44%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G++ + L+ A V+ R TPL A G ++VK L+ GA I
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L A G+ VV+ LLD A + + G + LH A + H V LL
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
H + +TN+ +T L AA V ++L + A+A+ +
Sbjct: 355 QHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401
Score = 39.5 bits (88), Expect = 0.037
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
N + AA G+L+ + +G ++ G ALH A++ GH VV LL A +
Sbjct: 42 NASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVD 101
Query: 231 LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+ G T L A+ +A VV++L A++
Sbjct: 102 AATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137
>BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 29
protein.
Length = 301
Score = 97.1 bits (231), Expect = 2e-19
Identities = 66/193 (34%), Positives = 99/193 (51%), Gaps = 13/193 (6%)
Query: 68 AARHGREGAVRILLEKFRPPV-CLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVK 126
AAR G +++LL R V C ++ GT T L A+ AGH+ V+ LV
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGT-----------TLLMVAAYAGHIDCVRELVL 67
Query: 127 AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDV 186
GAD+N + +T L A +G D+V++L GA K T L+ A+ G++ V
Sbjct: 68 QGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQV 127
Query: 187 VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAE 245
V+ LL GA + D+ GATAL AA+ G+ V+ LL GAK+ ++G PL A++
Sbjct: 128 VETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQ 187
Query: 246 RARASVVEILAAR 258
+ VV ++ R
Sbjct: 188 MGHSEVVRVMLLR 200
Score = 93.1 bits (221), Expect = 3e-18
Identities = 81/243 (33%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L F+AAR G +L L LL ++D C D T L+ AA G VR
Sbjct: 12 LANAAFWAARRG-NLALLKLLLNSGRVDVD-------CRDSHGTTLLMVAAYAGHIDCVR 63
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
L+ + + L+ E G TAL+ A+ GH +V+ L GA T+
Sbjct: 64 ELVLQ-GADINLQRES----------GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDE 112
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
T L AA G + +V+ L++HGA+IH T L +AA GYLDV++ LL SGA+V+
Sbjct: 113 GTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVN 172
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVV-EILA 256
G L A++ GH+ VV +L GA + +G T L AA + V+ E+L
Sbjct: 173 QPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLK 232
Query: 257 ARP 259
P
Sbjct: 233 FSP 235
Score = 69.7 bits (163), Expect = 3e-11
Identities = 47/149 (31%), Positives = 74/149 (49%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ +V+ L+K GA+++ +T L A G LD+++ L+ GA +++
Sbjct: 114 TALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQ 173
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+ L IA+ G+ +VV+ +L GA D G TAL AA G+ V+ LL
Sbjct: 174 PRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLKF 233
Query: 227 GAKMLTNENGMTPLQCAAERARASVVEIL 255
+ +NG + L A V +L
Sbjct: 234 SPTLGILKNGTSALHAAVLSGNIKTVALL 262
>AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens
cDNA FLJ25053 fis, clone CBL04266. ).
Length = 268
Score = 97.1 bits (231), Expect = 2e-19
Identities = 66/193 (34%), Positives = 99/193 (51%), Gaps = 13/193 (6%)
Query: 68 AARHGREGAVRILLEKFRPPV-CLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVK 126
AAR G +++LL R V C ++ GT T L A+ AGH+ V+ LV
Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGT-----------TLLMVAAYAGHIDCVRELVL 67
Query: 127 AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDV 186
GAD+N + +T L A +G D+V++L GA K T L+ A+ G++ V
Sbjct: 68 QGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDGGTALLAASQYGHMQV 127
Query: 187 VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAE 245
V+ LL GA + D+ GATAL AA+ G+ V+ LL GAK+ ++G PL A++
Sbjct: 128 VETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQ 187
Query: 246 RARASVVEILAAR 258
+ VV ++ R
Sbjct: 188 MGHSEVVRVMLLR 200
Score = 93.1 bits (221), Expect = 3e-18
Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 21/252 (8%)
Query: 19 LRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVR 78
L F+AAR G +L L LL ++D C D T L+ AA G VR
Sbjct: 12 LANAAFWAARRG-NLALLKLLLNSGRVDVD-------CRDSHGTTLLMVAAYAGHIDCVR 63
Query: 79 ILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
L+ + + L+ E G TAL+ A+ GH +V+ L GA T+
Sbjct: 64 ELVLQ-GADINLQRES----------GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDG 112
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
T L AA G + +V+ L++HGA+IH T L +AA GYLDV++ LL SGA+V+
Sbjct: 113 GTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVN 172
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVV-EILA 256
G L A++ GH+ VV +L GA + +G T L AA + V+ E+L
Sbjct: 173 QPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLK 232
Query: 257 ARPEVTRAEAIE 268
P + +A E
Sbjct: 233 FSPTLGILKANE 244
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 96.3 bits (229), Expect = 3e-19
Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L AS GH +V L+ GA+++ +T++ T L A E ++++ L +HGAD
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 720
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K T L++A + G + +V FLL GA V+ + G T LH AA+ GH ++ L
Sbjct: 721 QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 780
Query: 224 LDHGAK-MLTNENGMTPLQCAAERARASVVEIL-AARPEVT 262
L HGAK T NG T L A SVV+ L EVT
Sbjct: 781 LQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVT 821
Score = 95.1 bits (226), Expect = 7e-19
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLN----IDVCS-DGVKCTPLITAARHGREGAV 77
V F AR+G++ L+ T+ + LL+ ID + DG+ TPL AAR G + V
Sbjct: 259 VDFTARNGIT-PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGL--TPLHCAARSGHDQVV 315
Query: 78 RILLEKFRP----------PVCLETEGT----VKF--------DEYVIEGATALWCASGA 115
+LLE+ P P+ + +G VK D+ ++ TAL A+
Sbjct: 316 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 375
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH + K L+ A+ N TPL AC + R+ +++ LV++GA I + T +
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNE 234
+AA+ G+L++V LL +GA D + G TALH AA G VV LL +GA +
Sbjct: 436 HVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAR 495
Query: 235 NGMTPLQCAAERARASVVEIL 255
TPL A+ + +V++L
Sbjct: 496 EEQTPLHIASRLGKTEIVQLL 516
Score = 88.6 bits (210), Expect = 6e-17
Identities = 64/204 (31%), Positives = 104/204 (50%), Gaps = 15/204 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ G + D +G T L CA+ +GH +V+
Sbjct: 268 TPLHVASKRGNTNMVKLLLDR---------GGQI--DAKTRDGLTPLHCAARSGHDQVVE 316
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T+ +PL A ++ VK+L++H A + T L +AA+ G
Sbjct: 317 LLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCG 376
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + RAL G T LH A + V+ L+ +GA + E+G+TP+
Sbjct: 377 HYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIH 436
Query: 242 CAAERARASVVEIL---AARPEVT 262
AA ++V +L A P+VT
Sbjct: 437 VAAFMGHLNIVLLLLQNGASPDVT 460
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ LVK GA + T + TP+ A F G L+IV L+++GA
Sbjct: 396 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
N T L +AA G ++VV+ LL +GA VD RA T LH A+ G +V
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 515
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL H A NG TPL +A + V +L
Sbjct: 516 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVL 549
Score = 87.4 bits (207), Expect = 1e-16
Identities = 67/206 (32%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA + + +LLEK P T K G T L A+ + I
Sbjct: 598 TPLHVAAHYDNQKVALLLLEKGASP-----HATAK------NGYTPLHIAAKKNQMQIAS 646
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA+ N T+ TPL A EG D+V L+ GA+IH + K T L +AA +
Sbjct: 647 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 706
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
++V L GA D G T L A G+ +V LL GA + +NG TPL
Sbjct: 707 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLH 766
Query: 242 CAAERARASVVEIL---AARPEVTRA 264
AA++ ++ +L A+P T A
Sbjct: 767 QAAQQGHTHIINVLLQHGAKPNATTA 792
Score = 87.0 bits (206), Expect = 2e-16
Identities = 74/249 (29%), Positives = 110/249 (44%), Gaps = 14/249 (5%)
Query: 9 LVLFNELANSLR-ERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLIT 67
++L N+ +R + AAR + + LL ++ + ++ ++ TPL
Sbjct: 181 ILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTES-GFTPLHI 239
Query: 68 AARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKA 127
AA +G +LL + D G T L AS G+ +VK L+
Sbjct: 240 AAHYGNVNVATLLLNR-----------GAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G ++ TR TPL A G +V+ L+ GA + K + L +AA +++ V
Sbjct: 289 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 348
Query: 188 QFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAER 246
+ LL A VDD L TALH AA CGH V LLD A NG TPL A ++
Sbjct: 349 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 408
Query: 247 ARASVVEIL 255
R V+E+L
Sbjct: 409 NRIKVMELL 417
Score = 85.0 bits (201), Expect = 8e-16
Identities = 51/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AG+L V +K G D+N + L A EG + +V+ L+ G+ + A K
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
NT L IA+ G +VV+ L+ GA ++ ++ G T L+ AA+ H VV LL++GA
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 157
Query: 232 T-NENGMTPLQCAAERARASVVEIL 255
T E+G TPL A ++ V IL
Sbjct: 158 TATEDGFTPLAVALQQGHNQAVAIL 182
Score = 81.4 bits (192), Expect = 9e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G+ V++LL+ P D G T L ++ G + +
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHP-----------DAATTNGYTPLHISAREGQVDVAS 547
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGA + AT+ TPL A G LD+ K L++ A A K T L +AA+
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 607
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LL+ GA A G T LH AA+ + +LL++GA+ + + G+TPL
Sbjct: 608 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLH 667
Query: 242 CAAERARASVVEIL 255
A++ +V +L
Sbjct: 668 LASQEGHTDMVTLL 681
Score = 81.0 bits (191), Expect = 1e-14
Identities = 61/169 (36%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D +G TAL AS AG +VK LVK GA++N ++ TPL A E +D+VKYL+
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 150
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA+ A + T L +A +G+ V LL++ D + ALH AA
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTK 206
Query: 219 VVCSLL--DHGA----KMLTN---ENGMTPLQCAAERARASVVEILAAR 258
LL DH A KM+ N E+G TPL AA +V +L R
Sbjct: 207 SAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/169 (34%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G TAL A+ AG + +V+ L++ GA V+ R TPL A G+ +IV+ L++H A
Sbjct: 462 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
A T L I+A +G +DV LL++GA G T LH AA+ G V
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 581
Query: 223 LLD-HGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A +NG+TPL AA V +L + A A Y
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/125 (35%), Positives = 72/125 (57%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH+ +V+ L+ G+ V+ AT+ +T L A G+ ++VK LV+ GA+I
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 123
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + ++DVV++LL++GA G T L A + GH V LL
Sbjct: 124 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Query: 225 DHGAK 229
++ K
Sbjct: 184 ENDTK 188
Score = 78.2 bits (184), Expect = 9e-14
Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ +LLE L T+ +G T L A+ G L + K
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATK----------KGFTPLHVAAKYGSLDVAK 580
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A + TPL A + L+ GA H K T L IAA K
Sbjct: 581 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKN 640
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ + LL+ GA + G T LH A++ GH +V LLD GA + ++ ++G+T L
Sbjct: 641 QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLH 700
Query: 242 CAAERARASVVEIL 255
AA+ + +V +IL
Sbjct: 701 LAAQEDKVNVADIL 714
Score = 75.8 bits (178), Expect = 5e-13
Identities = 52/155 (33%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GHL IV L++ GA + T L A G++++V+ L+R+GA +
Sbjct: 431 GLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALV 490
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L IA+ G ++VQ LL A D G T LH +A G V LL
Sbjct: 491 DARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLL 550
Query: 225 DHG-AKMLTNENGMTPLQCAAERARASVVEILAAR 258
+ G A L + G TPL AA+ V ++L R
Sbjct: 551 EAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/209 (26%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA++G ++LL++ ++ G G T L A+ + +
Sbjct: 565 TPLHVAAKYGSLDVAKLLLQR---RAAADSAGK--------NGLTPLHVAAHYDNQKVAL 613
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + + TPL A + ++ I L+ +GA+ + K T L +A+ +G
Sbjct: 614 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEG 673
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQ 241
+ D+V LLD GA + G T+LH AA+ V L HGA + G TPL
Sbjct: 674 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAY 270
A +V L + A+ Y
Sbjct: 734 VACHYGNVKMVNFLLKQGANVNAKTKNGY 762
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/163 (32%), Positives = 76/163 (46%), Gaps = 13/163 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L+ A+ H+ +VK L++ GA+ + AT TPL A +G V L+ +
Sbjct: 130 GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTK- 188
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL--DSGARVDDRALC------GATALHFAAECGH 216
K L IAA K LL D A V + + G T LH AA G+
Sbjct: 189 ---GKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGN 245
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
V LL+ GA + T NG+TPL A++R ++V++L R
Sbjct: 246 VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Score = 57.6 bits (133), Expect = 1e-07
Identities = 34/92 (36%), Positives = 47/92 (51%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D + G T L A G++ +V L+K GA+VN T+ TPL A +G I+ L+
Sbjct: 722 DAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 781
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFL 190
+HGA + NT L IA GY+ VV L
Sbjct: 782 QHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 43.2 bits (97), Expect = 0.003
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+N + AA G LD V L G ++ G ALH AA+ GH +V LL G+ +
Sbjct: 31 SNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 90
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A+ +A VV++L
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVL 116
Score = 31.5 bits (68), Expect = 9.9
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 580 EAFCGVVCELLSRGAHVDAMDLDGITPL-VASIGGPAE 616
E G+V ELL RG+ VD+ G T L +AS+ G AE
Sbjct: 74 EGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAE 111
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 96.3 bits (229), Expect = 3e-19
Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L AS GH +V L+ GA+++ +T++ T L A E ++++ L +HGAD
Sbjct: 661 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 720
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K T L++A + G + +V FLL GA V+ + G T LH AA+ GH ++ L
Sbjct: 721 QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 780
Query: 224 LDHGAK-MLTNENGMTPLQCAAERARASVVEIL-AARPEVT 262
L HGAK T NG T L A SVV+ L EVT
Sbjct: 781 LQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVT 821
Score = 95.1 bits (226), Expect = 7e-19
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLN----IDVCS-DGVKCTPLITAARHGREGAV 77
V F AR+G++ L+ T+ + LL+ ID + DG+ TPL AAR G + V
Sbjct: 259 VDFTARNGIT-PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGL--TPLHCAARSGHDQVV 315
Query: 78 RILLEKFRP----------PVCLETEGT----VKF--------DEYVIEGATALWCASGA 115
+LLE+ P P+ + +G VK D+ ++ TAL A+
Sbjct: 316 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 375
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH + K L+ A+ N TPL AC + R+ +++ LV++GA I + T +
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNE 234
+AA+ G+L++V LL +GA D + G TALH AA G VV LL +GA +
Sbjct: 436 HVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAR 495
Query: 235 NGMTPLQCAAERARASVVEIL 255
TPL A+ + +V++L
Sbjct: 496 EEQTPLHIASRLGKTEIVQLL 516
Score = 88.6 bits (210), Expect = 6e-17
Identities = 64/204 (31%), Positives = 104/204 (50%), Gaps = 15/204 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ G + D +G T L CA+ +GH +V+
Sbjct: 268 TPLHVASKRGNTNMVKLLLDR---------GGQI--DAKTRDGLTPLHCAARSGHDQVVE 316
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T+ +PL A ++ VK+L++H A + T L +AA+ G
Sbjct: 317 LLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCG 376
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + RAL G T LH A + V+ L+ +GA + E+G+TP+
Sbjct: 377 HYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIH 436
Query: 242 CAAERARASVVEIL---AARPEVT 262
AA ++V +L A P+VT
Sbjct: 437 VAAFMGHLNIVLLLLQNGASPDVT 460
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ LVK GA + T + TP+ A F G L+IV L+++GA
Sbjct: 396 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 455
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
N T L +AA G ++VV+ LL +GA VD RA T LH A+ G +V
Sbjct: 456 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 515
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL H A NG TPL +A + V +L
Sbjct: 516 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVL 549
Score = 87.4 bits (207), Expect = 1e-16
Identities = 67/206 (32%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA + + +LLEK P T K G T L A+ + I
Sbjct: 598 TPLHVAAHYDNQKVALLLLEKGASP-----HATAK------NGYTPLHIAAKKNQMQIAS 646
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA+ N T+ TPL A EG D+V L+ GA+IH + K T L +AA +
Sbjct: 647 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 706
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
++V L GA D G T L A G+ +V LL GA + +NG TPL
Sbjct: 707 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLH 766
Query: 242 CAAERARASVVEIL---AARPEVTRA 264
AA++ ++ +L A+P T A
Sbjct: 767 QAAQQGHTHIINVLLQHGAKPNATTA 792
Score = 87.0 bits (206), Expect = 2e-16
Identities = 74/249 (29%), Positives = 110/249 (44%), Gaps = 14/249 (5%)
Query: 9 LVLFNELANSLR-ERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLIT 67
++L N+ +R + AAR + + LL ++ + ++ ++ TPL
Sbjct: 181 ILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTES-GFTPLHI 239
Query: 68 AARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKA 127
AA +G +LL + D G T L AS G+ +VK L+
Sbjct: 240 AAHYGNVNVATLLLNR-----------GAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G ++ TR TPL A G +V+ L+ GA + K + L +AA +++ V
Sbjct: 289 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 348
Query: 188 QFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAER 246
+ LL A VDD L TALH AA CGH V LLD A NG TPL A ++
Sbjct: 349 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 408
Query: 247 ARASVVEIL 255
R V+E+L
Sbjct: 409 NRIKVMELL 417
Score = 85.0 bits (201), Expect = 8e-16
Identities = 51/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AG+L V +K G D+N + L A EG + +V+ L+ G+ + A K
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
NT L IA+ G +VV+ L+ GA ++ ++ G T L+ AA+ H VV LL++GA
Sbjct: 98 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 157
Query: 232 T-NENGMTPLQCAAERARASVVEIL 255
T E+G TPL A ++ V IL
Sbjct: 158 TATEDGFTPLAVALQQGHNQAVAIL 182
Score = 81.4 bits (192), Expect = 9e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G+ V++LL+ P D G T L ++ G + +
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHP-----------DAATTNGYTPLHISAREGQVDVAS 547
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGA + AT+ TPL A G LD+ K L++ A A K T L +AA+
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 607
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LL+ GA A G T LH AA+ + +LL++GA+ + + G+TPL
Sbjct: 608 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLH 667
Query: 242 CAAERARASVVEIL 255
A++ +V +L
Sbjct: 668 LASQEGHTDMVTLL 681
Score = 81.0 bits (191), Expect = 1e-14
Identities = 61/169 (36%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D +G TAL AS AG +VK LVK GA++N ++ TPL A E +D+VKYL+
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 150
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA+ A + T L +A +G+ V LL++ D + ALH AA
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTK 206
Query: 219 VVCSLL--DHGA----KMLTN---ENGMTPLQCAAERARASVVEILAAR 258
LL DH A KM+ N E+G TPL AA +V +L R
Sbjct: 207 SAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 255
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/169 (34%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G TAL A+ AG + +V+ L++ GA V+ R TPL A G+ +IV+ L++H A
Sbjct: 462 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
A T L I+A +G +DV LL++GA G T LH AA+ G V
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 581
Query: 223 LLD-HGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A +NG+TPL AA V +L + A A Y
Sbjct: 582 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 630
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/125 (35%), Positives = 72/125 (57%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH+ +V+ L+ G+ V+ AT+ +T L A G+ ++VK LV+ GA+I
Sbjct: 64 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 123
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + ++DVV++LL++GA G T L A + GH V LL
Sbjct: 124 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 183
Query: 225 DHGAK 229
++ K
Sbjct: 184 ENDTK 188
Score = 78.2 bits (184), Expect = 9e-14
Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ +LLE L T+ +G T L A+ G L + K
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATK----------KGFTPLHVAAKYGSLDVAK 580
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A + TPL A + L+ GA H K T L IAA K
Sbjct: 581 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKN 640
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ + LL+ GA + G T LH A++ GH +V LLD GA + ++ ++G+T L
Sbjct: 641 QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLH 700
Query: 242 CAAERARASVVEIL 255
AA+ + +V +IL
Sbjct: 701 LAAQEDKVNVADIL 714
Score = 75.8 bits (178), Expect = 5e-13
Identities = 52/155 (33%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GHL IV L++ GA + T L A G++++V+ L+R+GA +
Sbjct: 431 GLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALV 490
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L IA+ G ++VQ LL A D G T LH +A G V LL
Sbjct: 491 DARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLL 550
Query: 225 DHG-AKMLTNENGMTPLQCAAERARASVVEILAAR 258
+ G A L + G TPL AA+ V ++L R
Sbjct: 551 EAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/209 (26%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA++G ++LL++ ++ G G T L A+ + +
Sbjct: 565 TPLHVAAKYGSLDVAKLLLQR---RAAADSAGK--------NGLTPLHVAAHYDNQKVAL 613
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + + TPL A + ++ I L+ +GA+ + K T L +A+ +G
Sbjct: 614 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEG 673
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQ 241
+ D+V LLD GA + G T+LH AA+ V L HGA + G TPL
Sbjct: 674 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAY 270
A +V L + A+ Y
Sbjct: 734 VACHYGNVKMVNFLLKQGANVNAKTKNGY 762
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/163 (32%), Positives = 76/163 (46%), Gaps = 13/163 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L+ A+ H+ +VK L++ GA+ + AT TPL A +G V L+ +
Sbjct: 130 GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTK- 188
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL--DSGARVDDRALC------GATALHFAAECGH 216
K L IAA K LL D A V + + G T LH AA G+
Sbjct: 189 ---GKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGN 245
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
V LL+ GA + T NG+TPL A++R ++V++L R
Sbjct: 246 VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Score = 57.6 bits (133), Expect = 1e-07
Identities = 34/92 (36%), Positives = 47/92 (51%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D + G T L A G++ +V L+K GA+VN T+ TPL A +G I+ L+
Sbjct: 722 DAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 781
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFL 190
+HGA + NT L IA GY+ VV L
Sbjct: 782 QHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 43.2 bits (97), Expect = 0.003
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+N + AA G LD V L G ++ G ALH AA+ GH +V LL G+ +
Sbjct: 31 SNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 90
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A+ +A VV++L
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVL 116
Score = 31.5 bits (68), Expect = 9.9
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 580 EAFCGVVCELLSRGAHVDAMDLDGITPL-VASIGGPAE 616
E G+V ELL RG+ VD+ G T L +AS+ G AE
Sbjct: 74 EGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAE 111
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 96.3 bits (229), Expect = 3e-19
Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L AS GH +V L+ GA+++ +T++ T L A E ++++ L +HGAD
Sbjct: 640 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD 699
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K T L++A + G + +V FLL GA V+ + G T LH AA+ GH ++ L
Sbjct: 700 QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL 759
Query: 224 LDHGAK-MLTNENGMTPLQCAAERARASVVEIL-AARPEVT 262
L HGAK T NG T L A SVV+ L EVT
Sbjct: 760 LQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVT 800
Score = 95.1 bits (226), Expect = 7e-19
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLN----IDVCS-DGVKCTPLITAARHGREGAV 77
V F AR+G++ L+ T+ + LL+ ID + DG+ TPL AAR G + V
Sbjct: 238 VDFTARNGIT-PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGL--TPLHCAARSGHDQVV 294
Query: 78 RILLEKFRP----------PVCLETEGT----VKF--------DEYVIEGATALWCASGA 115
+LLE+ P P+ + +G VK D+ ++ TAL A+
Sbjct: 295 ELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHC 354
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH + K L+ A+ N TPL AC + R+ +++ LV++GA I + T +
Sbjct: 355 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 414
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNE 234
+AA+ G+L++V LL +GA D + G TALH AA G VV LL +GA +
Sbjct: 415 HVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAR 474
Query: 235 NGMTPLQCAAERARASVVEIL 255
TPL A+ + +V++L
Sbjct: 475 EEQTPLHIASRLGKTEIVQLL 495
Score = 88.6 bits (210), Expect = 6e-17
Identities = 64/204 (31%), Positives = 104/204 (50%), Gaps = 15/204 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A++ G V++LL++ G + D +G T L CA+ +GH +V+
Sbjct: 247 TPLHVASKRGNTNMVKLLLDR---------GGQI--DAKTRDGLTPLHCAARSGHDQVVE 295
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T+ +PL A ++ VK+L++H A + T L +AA+ G
Sbjct: 296 LLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCG 355
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD A + RAL G T LH A + V+ L+ +GA + E+G+TP+
Sbjct: 356 HYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIH 415
Query: 242 CAAERARASVVEIL---AARPEVT 262
AA ++V +L A P+VT
Sbjct: 416 VAAFMGHLNIVLLLLQNGASPDVT 439
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+ G T L A + +++ LVK GA + T + TP+ A F G L+IV L+++GA
Sbjct: 375 LNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGA 434
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
N T L +AA G ++VV+ LL +GA VD RA T LH A+ G +V
Sbjct: 435 SPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQL 494
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL H A NG TPL +A + V +L
Sbjct: 495 LLQHMAHPDAATTNGYTPLHISAREGQVDVASVL 528
Score = 87.4 bits (207), Expect = 1e-16
Identities = 75/249 (30%), Positives = 110/249 (44%), Gaps = 14/249 (5%)
Query: 9 LVLFNELANSLR-ERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLIT 67
++L N+ +R + AAR + + LL +I + ++ ++ TPL
Sbjct: 160 ILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADIQSKMMVNRTTES-GFTPLHI 218
Query: 68 AARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKA 127
AA +G +LL + D G T L AS G+ +VK L+
Sbjct: 219 AAHYGNVNVATLLLNR-----------GAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 267
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G ++ TR TPL A G +V+ L+ GA + K + L +AA +++ V
Sbjct: 268 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 327
Query: 188 QFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAER 246
+ LL A VDD L TALH AA CGH V LLD A NG TPL A ++
Sbjct: 328 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 387
Query: 247 ARASVVEIL 255
R V+E+L
Sbjct: 388 NRIKVMELL 396
Score = 87.4 bits (207), Expect = 1e-16
Identities = 67/206 (32%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA + + +LLEK P T K G T L A+ + I
Sbjct: 577 TPLHVAAHYDNQKVALLLLEKGASP-----HATAK------NGYTPLHIAAKKNQMQIAS 625
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA+ N T+ TPL A EG D+V L+ GA+IH + K T L +AA +
Sbjct: 626 TLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQED 685
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
++V L GA D G T L A G+ +V LL GA + +NG TPL
Sbjct: 686 KVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLH 745
Query: 242 CAAERARASVVEIL---AARPEVTRA 264
AA++ ++ +L A+P T A
Sbjct: 746 QAAQQGHTHIINVLLQHGAKPNATTA 771
Score = 85.0 bits (201), Expect = 8e-16
Identities = 51/145 (35%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AG+L V +K G D+N + L A EG + +V+ L+ G+ + A K
Sbjct: 17 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 76
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
NT L IA+ G +VV+ L+ GA ++ ++ G T L+ AA+ H VV LL++GA
Sbjct: 77 NTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQS 136
Query: 232 T-NENGMTPLQCAAERARASVVEIL 255
T E+G TPL A ++ V IL
Sbjct: 137 TATEDGFTPLAVALQQGHNQAVAIL 161
Score = 81.4 bits (192), Expect = 9e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G+ V++LL+ P D G T L ++ G + +
Sbjct: 478 TPLHIASRLGKTEIVQLLLQHMAHP-----------DAATTNGYTPLHISAREGQVDVAS 526
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGA + AT+ TPL A G LD+ K L++ A A K T L +AA+
Sbjct: 527 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYD 586
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LL+ GA A G T LH AA+ + +LL++GA+ + + G+TPL
Sbjct: 587 NQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLH 646
Query: 242 CAAERARASVVEIL 255
A++ +V +L
Sbjct: 647 LASQEGHTDMVTLL 660
Score = 81.0 bits (191), Expect = 1e-14
Identities = 61/169 (36%), Positives = 83/169 (49%), Gaps = 13/169 (7%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D +G TAL AS AG +VK LVK GA++N ++ TPL A E +D+VKYL+
Sbjct: 70 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 129
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA+ A + T L +A +G+ V LL++ D + ALH AA
Sbjct: 130 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTK 185
Query: 219 VVCSLL--DHGA----KMLTN---ENGMTPLQCAAERARASVVEILAAR 258
LL DH A KM+ N E+G TPL AA +V +L R
Sbjct: 186 SAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNR 234
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/169 (34%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G TAL A+ AG + +V+ L++ GA V+ R TPL A G+ +IV+ L++H A
Sbjct: 441 IRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 500
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
A T L I+A +G +DV LL++GA G T LH AA+ G V
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKL 560
Query: 223 LLD-HGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
LL A +NG+TPL AA V +L + A A Y
Sbjct: 561 LLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGY 609
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/125 (35%), Positives = 72/125 (57%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH+ +V+ L+ G+ V+ AT+ +T L A G+ ++VK LV+ GA+I
Sbjct: 43 GLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANI 102
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L +AA + ++DVV++LL++GA G T L A + GH V LL
Sbjct: 103 NAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 162
Query: 225 DHGAK 229
++ K
Sbjct: 163 ENDTK 167
Score = 78.2 bits (184), Expect = 9e-14
Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ +LLE L T+ +G T L A+ G L + K
Sbjct: 511 TPLHISAREGQVDVASVLLEAGAAH-SLATK----------KGFTPLHVAAKYGSLDVAK 559
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A + TPL A + L+ GA H K T L IAA K
Sbjct: 560 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKN 619
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ + LL+ GA + G T LH A++ GH +V LLD GA + ++ ++G+T L
Sbjct: 620 QMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLH 679
Query: 242 CAAERARASVVEIL 255
AA+ + +V +IL
Sbjct: 680 LAAQEDKVNVADIL 693
Score = 75.8 bits (178), Expect = 5e-13
Identities = 52/155 (33%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T + A+ GHL IV L++ GA + T L A G++++V+ L+R+GA +
Sbjct: 410 GLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALV 469
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T L IA+ G ++VQ LL A D G T LH +A G V LL
Sbjct: 470 DARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLL 529
Query: 225 DHG-AKMLTNENGMTPLQCAAERARASVVEILAAR 258
+ G A L + G TPL AA+ V ++L R
Sbjct: 530 EAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 564
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/209 (26%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA++G ++LL++ ++ G G T L A+ + +
Sbjct: 544 TPLHVAAKYGSLDVAKLLLQR---RAAADSAGK--------NGLTPLHVAAHYDNQKVAL 592
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + + TPL A + ++ I L+ +GA+ + K T L +A+ +G
Sbjct: 593 LLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEG 652
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQ 241
+ D+V LLD GA + G T+LH AA+ V L HGA + G TPL
Sbjct: 653 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 712
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAY 270
A +V L + A+ Y
Sbjct: 713 VACHYGNVKMVNFLLKQGANVNAKTKNGY 741
Score = 63.3 bits (147), Expect = 3e-09
Identities = 52/163 (31%), Positives = 76/163 (46%), Gaps = 13/163 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L+ A+ H+ +VK L++ GA+ + AT TPL A +G V L+ +
Sbjct: 109 GFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTK- 167
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL--DSGARVDDRALC------GATALHFAAECGH 216
K L IAA K LL D A + + + G T LH AA G+
Sbjct: 168 ---GKVRLPALHIAARKDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGN 224
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
V LL+ GA + T NG+TPL A++R ++V++L R
Sbjct: 225 VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 267
Score = 57.6 bits (133), Expect = 1e-07
Identities = 34/92 (36%), Positives = 47/92 (51%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D + G T L A G++ +V L+K GA+VN T+ TPL A +G I+ L+
Sbjct: 701 DAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 760
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFL 190
+HGA + NT L IA GY+ VV L
Sbjct: 761 QHGAKPNATTANGNTALAIAKRLGYISVVDTL 792
Score = 43.2 bits (97), Expect = 0.003
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+N + AA G LD V L G ++ G ALH AA+ GH +V LL G+ +
Sbjct: 10 SNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSV 69
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A+ +A VV++L
Sbjct: 70 DSATKKGNTALHIASLAGQAEVVKVL 95
Score = 31.5 bits (68), Expect = 9.9
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 580 EAFCGVVCELLSRGAHVDAMDLDGITPL-VASIGGPAE 616
E G+V ELL RG+ VD+ G T L +AS+ G AE
Sbjct: 53 EGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAE 90
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 96.3 bits (229), Expect = 3e-19
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
A+ A+ GH+ +VK LV GA+V + TPL AA G + +VKYL+ G D+++
Sbjct: 209 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 268
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L +A Y G VV L+D GA V+ + G T LHFAA H A+ LL +
Sbjct: 269 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 328
Query: 227 GAKM-LTNENGMTPLQCAAERARAS 250
GA + + +++G TPL A R S
Sbjct: 329 GADVNMKSKDGKTPLHMTALHGRFS 353
Score = 88.6 bits (210), Expect = 6e-17
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH +VK L+ GA++N + + A + G +++VK LV HGA++
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K + T L AA G + VV++LLD G +++ G T LH A G VV L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D GA + NE G TPL AA ++ +E+L
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 325
Score = 83.8 bits (198), Expect = 2e-15
Identities = 72/243 (29%), Positives = 107/243 (44%), Gaps = 23/243 (9%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDG---VKCTPLITAARHGREGAVRI 79
V ++A G L L + E D + + D+ SD +PL AA HG A+ +
Sbjct: 542 VHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEV 601
Query: 80 LLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS 139
L++ + D G T L A+ GH+ V L+ GA + +
Sbjct: 602 LVQSL-----------LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILK 650
Query: 140 -TPLRAACFEGRLDIVKYLV-----RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDS 193
TP+ AA G + ++ L+ ++ DI N T LM++ G+ D V LL+
Sbjct: 651 RTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN--GQTPLMLSVLNGHTDCVYSLLNK 708
Query: 194 GARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVV 252
GA VD + G TALH A GH V +LL HGAK +L + G TP+ +A V+
Sbjct: 709 GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL 768
Query: 253 EIL 255
L
Sbjct: 769 GAL 771
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/183 (30%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ + + LV ++VN + R T L A F G ++VK L+ GA+I+
Sbjct: 142 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 201
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K + + AAY G+++VV+ L+ GA V + T LH AA G +VV LLD
Sbjct: 202 FDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDL 261
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
G M N G TPL A + VV L + + + + L + A+ C
Sbjct: 262 GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALC 321
Query: 286 LRM 288
L +
Sbjct: 322 LEL 324
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 83/192 (43%), Gaps = 15/192 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA G V+ LL+ V +E G T L A
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDL-----------GVDMNEPNAYGNTPLHVACYN 282
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G +V L+ GA VN TPL AA G L ++ LV +GAD++ +K T
Sbjct: 283 GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKT 341
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
L + A G Q ++ SGA +D G T LH AA GH ++ +L+ GA
Sbjct: 342 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 401
Query: 234 E-NGMTPLQCAA 244
+GM PL AA
Sbjct: 402 GIHGMFPLHLAA 413
Score = 67.7 bits (158), Expect = 1e-10
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH ++ L+ +GAD PL A G D + L+ G DI
Sbjct: 372 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDI 431
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + TCL AA G L+ + LL++GA + + G + LH+AA + + +L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 225 DHGAKML-TNENGMTPLQCAA 244
GA + +E G TPL AA
Sbjct: 492 GSGASVNDLDERGCTPLHYAA 512
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ + H A+ ++ LV GADVN ++ TPL GR + +++ GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I +K NT L IAA G+ ++ L+ SGA R + G LH AA G +
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G + T ++ G T L AA + +L
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 73 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L IAA + + L+ S V DRA G TALH AA GH +V
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--GRTALHHAAFSGHGEMVK 190
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVT 262
LL GA + ++ + AA VV++L + EVT
Sbjct: 191 LLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 16/191 (8%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+ LL++DV + + TPL AA G V +L+ + ++ +Y+++
Sbjct: 603 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQ---------GASILVKDYILK-R 651
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS----TPLRAACFEGRLDIVKYLVRHGA 162
T + A+ GH ++ L+ A+ +A TPL + G D V L+ GA
Sbjct: 652 TPIHAAATNGHSECLRLLI-GNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 710
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ +K+ T L A G+ + V LL GA+ R G T +H +A CGH V+ +
Sbjct: 711 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 770
Query: 223 LLDHGAKMLTN 233
LL A M N
Sbjct: 771 LLQSAASMDAN 781
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L + G + + ++++GA ++ + +TPL A G ++ L+ GAD
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 397
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K + L +AA G+ D + LL SG +D G T LH AA G+ + L
Sbjct: 398 TAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 224 LDHGAKMLTNEN-GMTPLQCAA 244
L+ GA + G +PL AA
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAA 479
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AAR+G E + L+ T G + I G L A+ +
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLI----------TSG-ADTAKRGIHGMFPLHLAALS 415
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G ++L+ +G D++ T L AA G L+ + L+ GAD +K +K+ + L
Sbjct: 416 GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 475
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + L+ SGA V+D G T LH+AA
Sbjct: 476 HYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 512
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A F G D V+ L+ D++ + T L AAY G ++++ L+ SGARV+ +
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 205 ATALHFA-AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A A C AV LL H A + ++N TPL AA E L
Sbjct: 108 LTPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+ DVN TPL AA + G +I++ L+ GA ++ + T L A
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN----- 235
+ VQ LL A V+ R T LH AA + AV C+ + +L+N N
Sbjct: 117 SCSEEAVQVLLKHSADVNARDKNWQTPLHIAA--ANKAVKCA--EALVPLLSNVNVSDRA 172
Query: 236 GMTPLQCAAERARASVVEILAAR 258
G T L AA +V++L +R
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSR 195
Score = 41.9 bits (94), Expect = 0.007
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G+L + L+ GAD N + +PL A + LV GA +
Sbjct: 438 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 497
Query: 165 HKANKYNNTCLMIAAYKGYLD-VVQFLLDSGARVDDRALCGATALHFAAECGH 216
+ ++ T L AA +++LL + A R G A+H++A GH
Sbjct: 498 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH 550
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 96.3 bits (229), Expect = 3e-19
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
A+ A+ GH+ +VK LV GA+V + TPL AA G + +VKYL+ G D+++
Sbjct: 206 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 265
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L +A Y G VV L+D GA V+ + G T LHFAA H A+ LL +
Sbjct: 266 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 325
Query: 227 GAKM-LTNENGMTPLQCAAERARAS 250
GA + + +++G TPL A R S
Sbjct: 326 GADVNMKSKDGKTPLHMTALHGRFS 350
Score = 88.6 bits (210), Expect = 6e-17
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH +VK L+ GA++N + + A + G +++VK LV HGA++
Sbjct: 170 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 229
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K + T L AA G + VV++LLD G +++ G T LH A G VV L+
Sbjct: 230 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 289
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D GA + NE G TPL AA ++ +E+L
Sbjct: 290 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 322
Score = 83.8 bits (198), Expect = 2e-15
Identities = 72/243 (29%), Positives = 107/243 (44%), Gaps = 23/243 (9%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDG---VKCTPLITAARHGREGAVRI 79
V ++A G L L + E D + + D+ SD +PL AA HG A+ +
Sbjct: 539 VHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEV 598
Query: 80 LLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS 139
L++ + D G T L A+ GH+ V L+ GA + +
Sbjct: 599 LVQSL-----------LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILK 647
Query: 140 -TPLRAACFEGRLDIVKYLV-----RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDS 193
TP+ AA G + ++ L+ ++ DI N T LM++ G+ D V LL+
Sbjct: 648 RTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN--GQTPLMLSVLNGHTDCVYSLLNK 705
Query: 194 GARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVV 252
GA VD + G TALH A GH V +LL HGAK +L + G TP+ +A V+
Sbjct: 706 GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL 765
Query: 253 EIL 255
L
Sbjct: 766 GAL 768
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/183 (30%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ + + LV ++VN + R T L A F G ++VK L+ GA+I+
Sbjct: 139 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 198
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K + + AAY G+++VV+ L+ GA V + T LH AA G +VV LLD
Sbjct: 199 FDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDL 258
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
G M N G TPL A + VV L + + + + L + A+ C
Sbjct: 259 GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALC 318
Query: 286 LRM 288
L +
Sbjct: 319 LEL 321
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 83/192 (43%), Gaps = 15/192 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA G V+ LL+ V +E G T L A
Sbjct: 231 CKDKKSYTPLHAAASSGMISVVKYLLDL-----------GVDMNEPNAYGNTPLHVACYN 279
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G +V L+ GA VN TPL AA G L ++ LV +GAD++ +K T
Sbjct: 280 GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKT 338
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
L + A G Q ++ SGA +D G T LH AA GH ++ +L+ GA
Sbjct: 339 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 398
Query: 234 E-NGMTPLQCAA 244
+GM PL AA
Sbjct: 399 GIHGMFPLHLAA 410
Score = 67.7 bits (158), Expect = 1e-10
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH ++ L+ +GAD PL A G D + L+ G DI
Sbjct: 369 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDI 428
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + TCL AA G L+ + LL++GA + + G + LH+AA + + +L+
Sbjct: 429 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 488
Query: 225 DHGAKML-TNENGMTPLQCAA 244
GA + +E G TPL AA
Sbjct: 489 GSGASVNDLDERGCTPLHYAA 509
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ + H A+ ++ LV GADVN ++ TPL GR + +++ GA
Sbjct: 301 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 360
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I +K NT L IAA G+ ++ L+ SGA R + G LH AA G +
Sbjct: 361 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 420
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G + T ++ G T L AA + +L
Sbjct: 421 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 454
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 70 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 129
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L IAA + + L+ S V DRA G TALH AA GH +V
Sbjct: 130 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--GRTALHHAAFSGHGEMVK 187
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVT 262
LL GA + ++ + AA VV++L + EVT
Sbjct: 188 LLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 230
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 16/191 (8%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+ LL++DV + + TPL AA G V +L+ + ++ +Y+++
Sbjct: 600 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQ---------GASILVKDYILK-R 648
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS----TPLRAACFEGRLDIVKYLVRHGA 162
T + A+ GH ++ L+ A+ +A TPL + G D V L+ GA
Sbjct: 649 TPIHAAATNGHSECLRLLI-GNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 707
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ +K+ T L A G+ + V LL GA+ R G T +H +A CGH V+ +
Sbjct: 708 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 767
Query: 223 LLDHGAKMLTN 233
LL A M N
Sbjct: 768 LLQSAASMDAN 778
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L + G + + ++++GA ++ + +TPL A G ++ L+ GAD
Sbjct: 335 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 394
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K + L +AA G+ D + LL SG +D G T LH AA G+ + L
Sbjct: 395 TAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 454
Query: 224 LDHGAKMLTNEN-GMTPLQCAA 244
L+ GA + G +PL AA
Sbjct: 455 LNTGADFNKKDKFGRSPLHYAA 476
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AAR+G E + L+ T G + I G L A+ +
Sbjct: 364 CEDKNGNTPLHIAARYGHELLINTLI----------TSG-ADTAKRGIHGMFPLHLAALS 412
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G ++L+ +G D++ T L AA G L+ + L+ GAD +K +K+ + L
Sbjct: 413 GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 472
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + L+ SGA V+D G T LH+AA
Sbjct: 473 HYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 509
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A F G D V+ L+ D++ + T L AAY G ++++ L+ SGARV+ +
Sbjct: 45 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 104
Query: 205 ATALHFA-AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A A C AV LL H A + ++N TPL AA E L
Sbjct: 105 LTPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 156
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+ DVN TPL AA + G +I++ L+ GA ++ + T L A
Sbjct: 54 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 113
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN----- 235
+ VQ LL A V+ R T LH AA + AV C+ + +L+N N
Sbjct: 114 SCSEEAVQVLLKHSADVNARDKNWQTPLHIAA--ANKAVKCA--EALVPLLSNVNVSDRA 169
Query: 236 GMTPLQCAAERARASVVEILAAR 258
G T L AA +V++L +R
Sbjct: 170 GRTALHHAAFSGHGEMVKLLLSR 192
Score = 41.9 bits (94), Expect = 0.007
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G+L + L+ GAD N + +PL A + LV GA +
Sbjct: 435 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 494
Query: 165 HKANKYNNTCLMIAAYKGYLD-VVQFLLDSGARVDDRALCGATALHFAAECGH 216
+ ++ T L AA +++LL + A R G A+H++A GH
Sbjct: 495 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH 547
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 96.3 bits (229), Expect = 3e-19
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
A+ A+ GH+ +VK LV GA+V + TPL AA G + +VKYL+ G D+++
Sbjct: 209 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 268
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L +A Y G VV L+D GA V+ + G T LHFAA H A+ LL +
Sbjct: 269 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 328
Query: 227 GAKM-LTNENGMTPLQCAAERARAS 250
GA + + +++G TPL A R S
Sbjct: 329 GADVNMKSKDGKTPLHMTALHGRFS 353
Score = 88.6 bits (210), Expect = 6e-17
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH +VK L+ GA++N + + A + G +++VK LV HGA++
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K + T L AA G + VV++LLD G +++ G T LH A G VV L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D GA + NE G TPL AA ++ +E+L
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 325
Score = 83.8 bits (198), Expect = 2e-15
Identities = 72/243 (29%), Positives = 107/243 (44%), Gaps = 23/243 (9%)
Query: 23 VFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDG---VKCTPLITAARHGREGAVRI 79
V ++A G L L + E D + + D+ SD +PL AA HG A+ +
Sbjct: 542 VHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEV 601
Query: 80 LLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS 139
L++ + D G T L A+ GH+ V L+ GA + +
Sbjct: 602 LVQSL-----------LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILK 650
Query: 140 -TPLRAACFEGRLDIVKYLV-----RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDS 193
TP+ AA G + ++ L+ ++ DI N T LM++ G+ D V LL+
Sbjct: 651 RTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN--GQTPLMLSVLNGHTDCVYSLLNK 708
Query: 194 GARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVV 252
GA VD + G TALH A GH V +LL HGAK +L + G TP+ +A V+
Sbjct: 709 GANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVL 768
Query: 253 EIL 255
L
Sbjct: 769 GAL 771
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/183 (30%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ + + LV ++VN + R T L A F G ++VK L+ GA+I+
Sbjct: 142 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 201
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K + + AAY G+++VV+ L+ GA V + T LH AA G +VV LLD
Sbjct: 202 FDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDL 261
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
G M N G TPL A + VV L + + + + L + A+ C
Sbjct: 262 GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALC 321
Query: 286 LRM 288
L +
Sbjct: 322 LEL 324
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 83/192 (43%), Gaps = 15/192 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA G V+ LL+ V +E G T L A
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDL-----------GVDMNEPNAYGNTPLHVACYN 282
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G +V L+ GA VN TPL AA G L ++ LV +GAD++ +K T
Sbjct: 283 GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKT 341
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
L + A G Q ++ SGA +D G T LH AA GH ++ +L+ GA
Sbjct: 342 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 401
Query: 234 E-NGMTPLQCAA 244
+GM PL AA
Sbjct: 402 GIHGMFPLHLAA 413
Score = 67.7 bits (158), Expect = 1e-10
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH ++ L+ +GAD PL A G D + L+ G DI
Sbjct: 372 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDI 431
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + TCL AA G L+ + LL++GA + + G + LH+AA + + +L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 225 DHGAKML-TNENGMTPLQCAA 244
GA + +E G TPL AA
Sbjct: 492 GSGASVNDLDERGCTPLHYAA 512
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ + H A+ ++ LV GADVN ++ TPL GR + +++ GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I +K NT L IAA G+ ++ L+ SGA R + G LH AA G +
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G + T ++ G T L AA + +L
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 73 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L IAA + + L+ S V DRA G TALH AA GH +V
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--GRTALHHAAFSGHGEMVK 190
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVT 262
LL GA + ++ + AA VV++L + EVT
Sbjct: 191 LLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Score = 63.7 bits (148), Expect = 2e-09
Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 16/191 (8%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+ LL++DV + + TPL AA G V +L+ + ++ +Y+++
Sbjct: 603 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQ---------GASILVKDYILK-R 651
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS----TPLRAACFEGRLDIVKYLVRHGA 162
T + A+ GH ++ L+ A+ +A TPL + G D V L+ GA
Sbjct: 652 TPIHAAATNGHSECLRLLI-GNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 710
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ +K+ T L A G+ + V LL GA+ R G T +H +A CGH V+ +
Sbjct: 711 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 770
Query: 223 LLDHGAKMLTN 233
LL A M N
Sbjct: 771 LLQSAASMDAN 781
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L + G + + ++++GA ++ + +TPL A G ++ L+ GAD
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 397
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K + L +AA G+ D + LL SG +D G T LH AA G+ + L
Sbjct: 398 TAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 224 LDHGAKMLTNEN-GMTPLQCAA 244
L+ GA + G +PL AA
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAA 479
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AAR+G E + L+ T G + I G L A+ +
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLI----------TSG-ADTAKRGIHGMFPLHLAALS 415
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G ++L+ +G D++ T L AA G L+ + L+ GAD +K +K+ + L
Sbjct: 416 GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 475
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + L+ SGA V+D G T LH+AA
Sbjct: 476 HYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 512
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A F G D V+ L+ D++ + T L AAY G ++++ L+ SGARV+ +
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 205 ATALHFA-AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A A C AV LL H A + ++N TPL AA E L
Sbjct: 108 LTPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+ DVN TPL AA + G +I++ L+ GA ++ + T L A
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN----- 235
+ VQ LL A V+ R T LH AA + AV C+ + +L+N N
Sbjct: 117 SCSEEAVQVLLKHSADVNARDKNWQTPLHIAA--ANKAVKCA--EALVPLLSNVNVSDRA 172
Query: 236 GMTPLQCAAERARASVVEILAAR 258
G T L AA +V++L +R
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSR 195
Score = 41.9 bits (94), Expect = 0.007
Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G+L + L+ GAD N + +PL A + LV GA +
Sbjct: 438 GRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASV 497
Query: 165 HKANKYNNTCLMIAAYKGYLD-VVQFLLDSGARVDDRALCGATALHFAAECGH 216
+ ++ T L AA +++LL + A R G A+H++A GH
Sbjct: 498 NDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGH 550
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 96.3 bits (229), Expect = 3e-19
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
A+ A+ GH+ +VK LV GA+V + TPL AA G + +VKYL+ G D+++
Sbjct: 209 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 268
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L +A Y G VV L+D GA V+ + G T LHFAA H A+ LL +
Sbjct: 269 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 328
Query: 227 GAKM-LTNENGMTPLQCAAERARAS 250
GA + + +++G TPL A R S
Sbjct: 329 GADVNMKSKDGKTPLHMTALHGRFS 353
Score = 88.6 bits (210), Expect = 6e-17
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH +VK L+ GA++N + + A + G +++VK LV HGA++
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K + T L AA G + VV++LLD G +++ G T LH A G VV L+
Sbjct: 233 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 292
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D GA + NE G TPL AA ++ +E+L
Sbjct: 293 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 325
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/183 (30%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ + + LV ++VN + R T L A F G ++VK L+ GA+I+
Sbjct: 142 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 201
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K + + AAY G+++VV+ L+ GA V + T LH AA G +VV LLD
Sbjct: 202 FDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDL 261
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
G M N G TPL A + VV L + + + + L + A+ C
Sbjct: 262 GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALC 321
Query: 286 LRM 288
L +
Sbjct: 322 LEL 324
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 83/192 (43%), Gaps = 15/192 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA G V+ LL+ V +E G T L A
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDL-----------GVDMNEPNAYGNTPLHVACYN 282
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G +V L+ GA VN TPL AA G L ++ LV +GAD++ +K T
Sbjct: 283 GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKT 341
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
L + A G Q ++ SGA +D G T LH AA GH ++ +L+ GA
Sbjct: 342 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 401
Query: 234 E-NGMTPLQCAA 244
+GM PL AA
Sbjct: 402 GIHGMFPLHLAA 413
Score = 67.7 bits (158), Expect = 1e-10
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH ++ L+ +GAD PL A G D + L+ G DI
Sbjct: 372 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDI 431
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + TCL AA G L+ + LL++GA + + G + LH+AA + + +L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 225 DHGAKML-TNENGMTPLQCAA 244
GA + +E G TPL AA
Sbjct: 492 GSGASVNDLDERGCTPLHYAA 512
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ + H A+ ++ LV GADVN ++ TPL GR + +++ GA
Sbjct: 304 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 363
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I +K NT L IAA G+ ++ L+ SGA R + G LH AA G +
Sbjct: 364 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 423
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G + T ++ G T L AA + +L
Sbjct: 424 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 73 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L IAA + + L+ S V DRA G TALH AA GH +V
Sbjct: 133 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--GRTALHHAAFSGHGEMVK 190
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVT 262
LL GA + ++ + AA VV++L + EVT
Sbjct: 191 LLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L + G + + ++++GA ++ + +TPL A G ++ L+ GAD
Sbjct: 338 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 397
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K + L +AA G+ D + LL SG +D G T LH AA G+ + L
Sbjct: 398 TAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 457
Query: 224 LDHGAKMLTNEN-GMTPLQCAA 244
L+ GA + G +PL AA
Sbjct: 458 LNTGADFNKKDKFGRSPLHYAA 479
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AAR+G E + L+ T G + I G L A+ +
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLI----------TSG-ADTAKRGIHGMFPLHLAALS 415
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G ++L+ +G D++ T L AA G L+ + L+ GAD +K +K+ + L
Sbjct: 416 GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 475
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + L+ SGA V+D G T LH+AA
Sbjct: 476 HYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 512
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A F G D V+ L+ D++ + T L AAY G ++++ L+ SGARV+ +
Sbjct: 48 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 107
Query: 205 ATALHFA-AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A A C AV LL H A + ++N TPL AA E L
Sbjct: 108 LTPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 159
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+ DVN TPL AA + G +I++ L+ GA ++ + T L A
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN----- 235
+ VQ LL A V+ R T LH AA + AV C+ + +L+N N
Sbjct: 117 SCSEEAVQVLLKHSADVNARDKNWQTPLHIAA--ANKAVKCA--EALVPLLSNVNVSDRA 172
Query: 236 GMTPLQCAAERARASVVEILAAR 258
G T L AA +V++L +R
Sbjct: 173 GRTALHHAAFSGHGEMVKLLLSR 195
Score = 44.8 bits (101), Expect = 0.001
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Query: 62 CTPLITAARHGREG-AVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAI 120
CTPL AA +G + LL P + +G Y L A +
Sbjct: 505 CTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQG-YNAVHYSAAYGHRLCLQLIASETPL 563
Query: 121 VKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+ +G D+ + R +PL A + G ++ LV+ D+ N T L +A
Sbjct: 564 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 623
Query: 179 AYKGYLDVVQFLLDSGARVDDR-ALCGATALHFAAECGHA 217
A+KG+++ V L++ GA + + + T +H AA GH+
Sbjct: 624 AFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHS 663
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N+ + L +AAY G+ ++ L+ S +D R G T L AA GH V L++ G
Sbjct: 580 NRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 639
Query: 228 AKMLTNENGM--TPLQCAAERARASVVEILAARPEVTRAEAIE 268
A +L + + TP+ AA + + +L E A I+
Sbjct: 640 ASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQ 682
>AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein.
Length = 1644
Score = 96.3 bits (229), Expect = 3e-19
Identities = 60/158 (37%), Positives = 85/158 (53%), Gaps = 1/158 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+G G L + + L+ GA V+ R PL A +G IV+ L+ G D+
Sbjct: 862 GETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDV 921
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++K T LM+AA +G+L V+FLL GA + G +AL +A GH AVV L+
Sbjct: 922 NLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLV 981
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEV 261
+ GA + T++NG TPL AA A V L + V
Sbjct: 982 EEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAV 1019
Score = 76.6 bits (180), Expect = 3e-13
Identities = 56/167 (33%), Positives = 85/167 (50%), Gaps = 11/167 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AAR G VR+LLE+ C V + +G T L A+ GHL+ V+
Sbjct: 898 PLFCAARQGHWQIVRLLLERG----C-----DVNLSDK--QGRTPLMVAACEGHLSTVEF 946
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L+ GA ++ + + L AC +G +V+YLV GA I + +K T L +AA+ G
Sbjct: 947 LLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGD 1006
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ V +L++ GA ++ G L A C + +VV +LL GAK+
Sbjct: 1007 AETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKL 1053
Score = 64.9 bits (151), Expect = 9e-10
Identities = 69/222 (31%), Positives = 99/222 (44%), Gaps = 27/222 (12%)
Query: 52 NIDVCSDGVKCTPLITAARH-GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALW 110
N++ ++ + P++ H G E V +LLE CL+ GT + G TAL
Sbjct: 708 NVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEF---GACLD--GTSE------NGMTALC 756
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR--------HGA 162
A+ AGH+ +V L K G V+H + L + G DI++YL+
Sbjct: 757 YAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPG 816
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLL----DSGARVDDR-ALCGATALHFAAECGHA 217
+ K++ L AA G+ VVQ LL + V+ L G TAL AA G
Sbjct: 817 TLRKSHALQQ-ALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKL 875
Query: 218 AVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
V LL HGA + TN G+ PL CAA + +V +L R
Sbjct: 876 EVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLER 917
Score = 48.8 bits (111), Expect = 6e-05
Identities = 34/130 (26%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 131 VNHATRTVSTPLRAA--CFEGRLDIVKYLVRHGADI-HKANKYNNT-CLMIAAYKGYLDV 186
+ ++T +S L + + + + + L+ GA++ ++ NN L + ++ G+ +V
Sbjct: 674 IGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEV 733
Query: 187 VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAE 245
V LL+ GA +D + G TAL +AA GH +VC L G ++ ++ G L +A
Sbjct: 734 VTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSAL 793
Query: 246 RARASVVEIL 255
R +++ L
Sbjct: 794 RGHGDILQYL 803
Score = 33.1 bits (72), Expect = 3.2
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
L++ GA +D D N RTPL +A Y +A V L+ +GA ++ +D
Sbjct: 980 LVEEGAAIDQTDKNGRTPLDLAAF-----------YGDA--ETVLYLVEKGAVIEHVDHS 1026
Query: 603 GITPLVASIGGPAESLVRSALR 624
G+ PL +IG S+V + LR
Sbjct: 1027 GMRPLDRAIGCRNTSVVVALLR 1048
Score = 32.3 bits (70), Expect = 5.6
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 13/67 (19%)
Query: 541 RLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMD 600
RLLL+ G DV+ +D RTPL VA L++ V LLS+GA + ++D
Sbjct: 912 RLLLERGCDVNLSDKQGRTPLMVAACEGHLST-------------VEFLLSKGAALSSLD 958
Query: 601 LDGITPL 607
+G++ L
Sbjct: 959 KEGLSAL 965
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 96.3 bits (229), Expect = 3e-19
Identities = 58/145 (40%), Positives = 81/145 (55%), Gaps = 2/145 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
A+ A+ GH+ +VK LV GA+V + TPL AA G + +VKYL+ G D+++
Sbjct: 182 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 241
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L +A Y G VV L+D GA V+ + G T LHFAA H A+ LL +
Sbjct: 242 NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGN 301
Query: 227 GAKM-LTNENGMTPLQCAAERARAS 250
GA + + +++G TPL A R S
Sbjct: 302 GADVNMKSKDGKTPLHMTALHGRFS 326
Score = 88.6 bits (210), Expect = 6e-17
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH +VK L+ GA++N + + A + G +++VK LV HGA++
Sbjct: 146 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 205
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K + T L AA G + VV++LLD G +++ G T LH A G VV L+
Sbjct: 206 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 265
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D GA + NE G TPL AA ++ +E+L
Sbjct: 266 DCGAIVNQKNEKGFTPLHFAAASTHGALCLELL 298
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/183 (30%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ + + LV ++VN + R T L A F G ++VK L+ GA+I+
Sbjct: 115 TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINA 174
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K + + AAY G+++VV+ L+ GA V + T LH AA G +VV LLD
Sbjct: 175 FDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDL 234
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
G M N G TPL A + VV L + + + + L + A+ C
Sbjct: 235 GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALC 294
Query: 286 LRM 288
L +
Sbjct: 295 LEL 297
Score = 72.1 bits (169), Expect = 6e-12
Identities = 66/245 (26%), Positives = 107/245 (43%), Gaps = 22/245 (8%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+ LL++DV + + TPL AA G V +L+ + ++ +Y+++
Sbjct: 576 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQ---------GASILVKDYILK-R 624
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS----TPLRAACFEGRLDIVKYLVRHGA 162
T + A+ GH ++ L+ A+ +A TPL + G D V L+ GA
Sbjct: 625 TPIHAAATNGHSECLRLLI-GNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 683
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ +K+ T L A G+ + V LL GA+ R G T +H +A CGH V+ +
Sbjct: 684 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 743
Query: 223 LLDHGAKMLTN-----ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASF 277
LL A M N +G T L A + VE+L + + E A+ L +
Sbjct: 744 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEG-NAFSPLHCAV 802
Query: 278 ANDKE 282
ND E
Sbjct: 803 INDNE 807
Score = 70.1 bits (164), Expect = 2e-11
Identities = 63/192 (32%), Positives = 83/192 (43%), Gaps = 15/192 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA G V+ LL+ V +E G T L A
Sbjct: 207 CKDKKSYTPLHAAASSGMISVVKYLLDL-----------GVDMNEPNAYGNTPLHVACYN 255
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G +V L+ GA VN TPL AA G L ++ LV +GAD++ +K T
Sbjct: 256 GQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGAL-CLELLVGNGADVNMKSKDGKT 314
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
L + A G Q ++ SGA +D G T LH AA GH ++ +L+ GA
Sbjct: 315 PLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKR 374
Query: 234 E-NGMTPLQCAA 244
+GM PL AA
Sbjct: 375 GIHGMFPLHLAA 386
Score = 67.7 bits (158), Expect = 1e-10
Identities = 45/141 (31%), Positives = 68/141 (48%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH ++ L+ +GAD PL A G D + L+ G DI
Sbjct: 345 GNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDI 404
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + TCL AA G L+ + LL++GA + + G + LH+AA + + +L+
Sbjct: 405 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 464
Query: 225 DHGAKML-TNENGMTPLQCAA 244
GA + +E G TPL AA
Sbjct: 465 GSGASVNDLDERGCTPLHYAA 485
Score = 67.3 bits (157), Expect = 2e-10
Identities = 55/200 (27%), Positives = 84/200 (42%), Gaps = 12/200 (6%)
Query: 60 VKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLA 119
+K TP+ AA +G +R+L+ P ++ + G T L + GH
Sbjct: 622 LKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDG--------NGQTPLMLSVLNGHTD 673
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
V L+ GA+V+ + T L G + V L++HGA + T + ++A
Sbjct: 674 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 733
Query: 180 YKGYLDVVQFLLDSGARVDDRALC----GATALHFAAECGHAAVVCSLLDHGAKMLTNEN 235
G++ V+ LL S A +D G TALH+A GH V LL+ T N
Sbjct: 734 ACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGN 793
Query: 236 GMTPLQCAAERARASVVEIL 255
+PL CA E+L
Sbjct: 794 AFSPLHCAVINDNEGAAEML 813
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ + H A+ ++ LV GADVN ++ TPL GR + +++ GA
Sbjct: 277 KGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGA 336
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I +K NT L IAA G+ ++ L+ SGA R + G LH AA G +
Sbjct: 337 VIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRK 396
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G + T ++ G T L AA + +L
Sbjct: 397 LLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 430
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/163 (33%), Positives = 77/163 (47%), Gaps = 6/163 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 46 EKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 105
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L IAA + + L+ S V DRA G TALH AA GH +V
Sbjct: 106 VNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRA--GRTALHHAAFSGHGEMVK 163
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVT 262
LL GA + ++ + AA VV++L + EVT
Sbjct: 164 LLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 206
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L + G + + ++++GA ++ + +TPL A G ++ L+ GAD
Sbjct: 311 DGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGAD 370
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K + L +AA G+ D + LL SG +D G T LH AA G+ + L
Sbjct: 371 TAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 430
Query: 224 LDHGAKMLTNEN-GMTPLQCAA 244
L+ GA + G +PL AA
Sbjct: 431 LNTGADFNKKDKFGRSPLHYAA 452
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L A +G E V +LLE+ V +TEG + L CA + +
Sbjct: 764 TALHWACYNGHETCVELLLEQ---EVFQKTEGNA---------FSPLHCAVINDNEGAAE 811
Query: 123 RLVKA-GADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
L+ GA + +AT + TPL AA F ++ ++ L+ H A ++ + T LM+AA
Sbjct: 812 MLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAE 871
Query: 181 KGYLDVVQFLLDS-GARVDDRALCGATALHFAAECGHAA----VVCSLLDHGAKMLTNEN 235
G + V+ L+ S A + + TALH A GH ++ + D TN
Sbjct: 872 NGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAA 931
Query: 236 GMTPLQCAAERARASVVEILAAR 258
TPL AA VV+ L +
Sbjct: 932 LQTPLHVAARNGLTMVVQELLGK 954
Score = 55.2 bits (127), Expect = 7e-07
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AAR+G E + L+ T G + I G L A+ +
Sbjct: 340 CEDKNGNTPLHIAARYGHELLINTLI----------TSG-ADTAKRGIHGMFPLHLAALS 388
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G ++L+ +G D++ T L AA G L+ + L+ GAD +K +K+ + L
Sbjct: 389 GFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPL 448
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + L+ SGA V+D G T LH+AA
Sbjct: 449 HYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 485
Score = 51.2 bits (117), Expect = 1e-05
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A F G D V+ L+ D++ + T L AAY G ++++ L+ SGARV+ +
Sbjct: 21 AIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKW 80
Query: 205 ATALHFA-AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A A C AV LL H A + ++N TPL AA E L
Sbjct: 81 LTPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 132
Score = 48.8 bits (111), Expect = 6e-05
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 9/187 (4%)
Query: 62 CTPLITAARHGREG-AVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAI 120
CTPL AA +G + LL P + +G Y L A +
Sbjct: 478 CTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG-YNAVHYSAAYGHRLCLQLIASETPL 536
Query: 121 VKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+ +G D+ + R +PL A + G ++ LV+ D+ N T L +A
Sbjct: 537 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 596
Query: 179 AYKGYLDVVQFLLDSGARVDDR-ALCGATALHFAAECGHAAVVCSLLDH----GAKMLTN 233
A+KG+++ V L++ GA + + + T +H AA GH+ + L+ + A + +
Sbjct: 597 AFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQD 656
Query: 234 ENGMTPL 240
NG TPL
Sbjct: 657 GNGQTPL 663
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+ DVN TPL AA + G +I++ L+ GA ++ + T L A
Sbjct: 30 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 89
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN----- 235
+ VQ LL A V+ R T LH AA + AV C+ + +L+N N
Sbjct: 90 SCSEEAVQVLLKHSADVNARDKNWQTPLHIAA--ANKAVKCA--EALVPLLSNVNVSDRA 145
Query: 236 GMTPLQCAAERARASVVEILAAR 258
G T L AA +V++L +R
Sbjct: 146 GRTALHHAAFSGHGEMVKLLLSR 168
Score = 33.9 bits (74), Expect = 1.8
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 105 GATALWCASGAGHLAIVKRLVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L A+ G V+ LV A A++ + +T L AC +G ++ D
Sbjct: 862 GKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITD 921
Query: 164 IHKANKYN---NTCLMIAAYKGYLDVVQFLLDSGARV 197
+ N N T L +AA G VVQ LL GA V
Sbjct: 922 RNLINATNAALQTPLHVAARNGLTMVVQELLGKGASV 958
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS G++ +V+ L+ GA + T+ TPL A G + I + L+ HGA I
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + + +AA +LD V+ LL A +DD L T LH AA CGH V LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 225 DHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
D GAK + NG TPL A ++ V+E+L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELL 390
Score = 94.7 bits (225), Expect = 9e-19
Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 1/161 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D G T L AS GHL IVK L++ GA N + V TPL A G ++ KYL+
Sbjct: 398 DAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++ A ++ K + T L AA G+ ++V+ LL++ A + G T LH AA GH
Sbjct: 458 QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVE 517
Query: 219 VVCSLLD-HGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
V +LL+ ++ + G TPL AA+ + V E+L R
Sbjct: 518 TVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/191 (33%), Positives = 93/191 (48%), Gaps = 12/191 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA G ++LL+K P + + G T L A H+ +++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKP-----------NSRALNGFTPLHIACKKNHVRVME 388
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+K GA ++ T + TPL A F G L IVK L++ GA + +N T L +AA G
Sbjct: 389 LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 448
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
+ +V ++LL + A+V+ +A T LH AA GH +V LL++ A L G TPL
Sbjct: 449 HTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLH 508
Query: 242 CAAERARASVV 252
AA V
Sbjct: 509 IAAREGHVETV 519
Score = 89.4 bits (212), Expect = 4e-17
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V LLEK C+ +G T L A+ G + + +
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMTKKGF-----------TPLHVAAKYGKVRVAE 553
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A N A + TPL A LDIVK L+ G H T L IAA +
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQN 613
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++V + LL G + ++ G T LH AA+ GHA +V LL A L N++G+TPL
Sbjct: 614 QVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH 673
Query: 242 CAAERARASVVEIL 255
A+ V ++L
Sbjct: 674 LVAQEGHVPVADVL 687
Score = 88.2 bits (209), Expect = 8e-17
Identities = 67/197 (34%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G VR+LL++ +ET+ DE T L CA+ GH+ I +
Sbjct: 241 TPLHIASRRGNVIMVRLLLDRGAQ---IETKTK---DEL-----TPLHCAARNGHVRISE 289
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA + T+ +P+ A LD V+ L+++ A+I + T L +AA+ G
Sbjct: 290 ILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCG 349
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD GA+ + RAL G T LH A + H V+ LL GA + E+G+TPL
Sbjct: 350 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLH 409
Query: 242 CAAERARASVVEILAAR 258
A+ +V+ L R
Sbjct: 410 VASFMGHLPIVKNLLQR 426
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 1/160 (0%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
+ D+ ++ T L A+ GH + K L+ GA N TPL AC + + +++
Sbjct: 330 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMEL 389
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
L++ GA I + T L +A++ G+L +V+ LL GA + + T LH AA GH
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 217 AAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEIL 255
V LL + AK+ ++ TPL CAA ++V++L
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 81.8 bits (193), Expect = 7e-15
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G T L A+ GH +V L+ A+ N ++ TPL EG + + L++HG
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 692
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L +A++ G + +V+FLL A V+ + G + LH AA+ GH +V
Sbjct: 693 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 752
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL +GA + +G TPL A SV ++L
Sbjct: 753 LLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V++LLE P T G T L A+ GH+ V
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGH-----------TPLHIAAREGHVETVL 520
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A T+ TPL A G++ + + L+ A + A K T L +A +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
LD+V+ LL G A G T LH AA+ V SLL +G + G+TPL
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLH 640
Query: 242 CAAERARASVVEILAAR 258
AA+ A +V +L ++
Sbjct: 641 LAAQEGHAEMVALLLSK 657
Score = 77.8 bits (183), Expect = 1e-13
Identities = 66/220 (30%), Positives = 111/220 (50%), Gaps = 19/220 (8%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
+K D + + ++I+ C+ +G+ L + +EG V++++E + LET T K
Sbjct: 26 DKALDHLRNGVDINTCNQNGLNGLHLAS-----KEGHVKMVVELLHKEIILET--TTK-- 76
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL A+ AG +V+ LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 77 ----KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA+ + A + T L +A +G+ +VV L++ G + R ALH AA
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVR----LPALHIAARNDDTRT 188
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
LL + + ++ G TPL AA +V ++L R
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 76.2 bits (179), Expect = 4e-13
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ AGH + K L++ A VN + TPL A G ++VK L+ + A+ +
Sbjct: 439 TPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNL 498
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
A +T L IAA +G+++ V LL+ A G T LH AA+ G V LL+
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Query: 227 GA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
A +NG+TPL A +V++L R + A Y L + A +
Sbjct: 559 DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA-AKQNQVEV 617
Query: 286 LRMAYQY 292
R QY
Sbjct: 618 ARSLLQY 624
Score = 74.1 bits (174), Expect = 1e-12
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR+G ILL+ P+ +T+ G + + A+ HL V+
Sbjct: 274 TPLHCAARNGHVRISEILLDH-GAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 322
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+++ T TPL A G + K L+ GA + T L IA K
Sbjct: 323 LLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 382
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++ V++ LL +GA +D G T LH A+ GH +V +LL GA ++N TPL
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 242 CAAERARASVVEILAARPEVTRAEA 266
AA V + L A+A
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKA 467
Score = 72.9 bits (171), Expect = 3e-12
Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 21/231 (9%)
Query: 26 AARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFR 85
AAR+G T+ ALL EK+ + C TPL AA++G+ +LLE+
Sbjct: 510 AAREGHVETVLALL-EKEASQ--------ACMTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
P G G T L A +L IVK L+ G + TPL A
Sbjct: 561 HP---NAAGK--------NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 609
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
+ ++++ + L+++G + + T L +AA +G+ ++V LL A + G
Sbjct: 610 AKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGL 669
Query: 206 TALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A+ GH V L+ HG + T G TPL A+ +V+ L
Sbjct: 670 TPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Score = 71.3 bits (167), Expect = 1e-11
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+ AT+ A+ +G+L ++ G D+N + L A EG + +V L+
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEII 70
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K NT L IAA G +VV+ L++ GA V+ ++ G T L+ AA+ H VV L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVV 252
L++GA + E+G TPL A ++ +VV
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 70.5 bits (165), Expect = 2e-11
Identities = 62/207 (29%), Positives = 88/207 (42%), Gaps = 12/207 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G + LL+ K + + T L CA+ GH +VK
Sbjct: 439 TPLHMAARAGHTEVAKYLLQN-----------KAKVNAKAKDDQTPLHCAARIGHTNMVK 487
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+ N AT TPL A EG ++ V L+ A K T L +AA G
Sbjct: 488 LLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYG 547
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQ 241
+ V + LL+ A + G T LH A + +V LL G + NG TPL
Sbjct: 548 KVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLH 607
Query: 242 CAAERARASVVEILAARPEVTRAEAIE 268
AA++ + V L AE+++
Sbjct: 608 IAAKQNQVEVARSLLQYGGSANAESVQ 634
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ +L + + L+ GA VN + TPL A G + +V+ L+ GA I
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K T L AA G++ + + LLD GA + + G + +H AA+ H V LL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
+ A++ +T ++ +TPL AA V ++L + + A+ +
Sbjct: 326 QYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 372
Score = 69.3 bits (162), Expect = 4e-11
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++T TPL A L++ + L+ GA ++ + T L IA+ +G + +V+ LLD G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
A+++ + T LH AA GH + LLDHGA + +NG++P+ AA+ V
Sbjct: 263 AQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 254 IL 255
+L
Sbjct: 323 LL 324
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + + + L++ G N + TPL A EG ++V L+ A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L + A +G++ V L+ G VD G T LH A+ G+ +V LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H A + + G +PL AA++ +V +L
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 33.5 bits (73), Expect = 2.4
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 26/127 (20%)
Query: 507 RSGQTLLHLAADRNTPVDDFHTSDVCQFPCA------RTSRLLLDCGADVDAADMNRRTP 560
R ++ L DR ++ ++ CA R S +LLD GA + A N +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 561 LHVA-----------LISYQLTSDD------REQYNEAFCG---VVCELLSRGAHVDAMD 600
+H+A L+ Y DD + A CG V LL +GA ++
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 601 LDGITPL 607
L+G TPL
Sbjct: 369 LNGFTPL 375
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS G++ +V+ L+ GA + T+ TPL A G + I + L+ HGA I
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + + +AA +LD V+ LL A +DD L T LH AA CGH V LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 225 DHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
D GAK + NG TPL A ++ V+E+L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELL 390
Score = 94.7 bits (225), Expect = 9e-19
Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 1/161 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D G T L AS GHL IVK L++ GA N + V TPL A G ++ KYL+
Sbjct: 398 DAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++ A ++ K + T L AA G+ ++V+ LL++ A + G T LH AA GH
Sbjct: 458 QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVE 517
Query: 219 VVCSLLD-HGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
V +LL+ ++ + G TPL AA+ + V E+L R
Sbjct: 518 TVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/191 (33%), Positives = 93/191 (48%), Gaps = 12/191 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA G ++LL+K P + + G T L A H+ +++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKP-----------NSRALNGFTPLHIACKKNHVRVME 388
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+K GA ++ T + TPL A F G L IVK L++ GA + +N T L +AA G
Sbjct: 389 LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 448
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
+ +V ++LL + A+V+ +A T LH AA GH +V LL++ A L G TPL
Sbjct: 449 HTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLH 508
Query: 242 CAAERARASVV 252
AA V
Sbjct: 509 IAAREGHVETV 519
Score = 89.4 bits (212), Expect = 4e-17
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V LLEK C+ +G T L A+ G + + +
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMTKKGF-----------TPLHVAAKYGKVRVAE 553
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A N A + TPL A LDIVK L+ G H T L IAA +
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQN 613
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++V + LL G + ++ G T LH AA+ GHA +V LL A L N++G+TPL
Sbjct: 614 QVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH 673
Query: 242 CAAERARASVVEIL 255
A+ V ++L
Sbjct: 674 LVAQEGHVPVADVL 687
Score = 88.2 bits (209), Expect = 8e-17
Identities = 67/197 (34%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G VR+LL++ +ET+ DE T L CA+ GH+ I +
Sbjct: 241 TPLHIASRRGNVIMVRLLLDRGAQ---IETKTK---DEL-----TPLHCAARNGHVRISE 289
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA + T+ +P+ A LD V+ L+++ A+I + T L +AA+ G
Sbjct: 290 ILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCG 349
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD GA+ + RAL G T LH A + H V+ LL GA + E+G+TPL
Sbjct: 350 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLH 409
Query: 242 CAAERARASVVEILAAR 258
A+ +V+ L R
Sbjct: 410 VASFMGHLPIVKNLLQR 426
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 1/160 (0%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
+ D+ ++ T L A+ GH + K L+ GA N TPL AC + + +++
Sbjct: 330 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMEL 389
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
L++ GA I + T L +A++ G+L +V+ LL GA + + T LH AA GH
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 217 AAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEIL 255
V LL + AK+ ++ TPL CAA ++V++L
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 81.8 bits (193), Expect = 7e-15
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G T L A+ GH +V L+ A+ N ++ TPL EG + + L++HG
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 692
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L +A++ G + +V+FLL A V+ + G + LH AA+ GH +V
Sbjct: 693 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 752
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL +GA + +G TPL A SV ++L
Sbjct: 753 LLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V++LLE P T G T L A+ GH+ V
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGH-----------TPLHIAAREGHVETVL 520
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A T+ TPL A G++ + + L+ A + A K T L +A +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
LD+V+ LL G A G T LH AA+ V SLL +G + G+TPL
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLH 640
Query: 242 CAAERARASVVEILAAR 258
AA+ A +V +L ++
Sbjct: 641 LAAQEGHAEMVALLLSK 657
Score = 77.8 bits (183), Expect = 1e-13
Identities = 66/220 (30%), Positives = 111/220 (50%), Gaps = 19/220 (8%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
+K D + + ++I+ C+ +G+ L + +EG V++++E + LET T K
Sbjct: 26 DKALDHLRNGVDINTCNQNGLNGLHLAS-----KEGHVKMVVELLHKEIILET--TTK-- 76
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL A+ AG +V+ LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 77 ----KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA+ + A + T L +A +G+ +VV L++ G + R ALH AA
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVR----LPALHIAARNDDTRT 188
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
LL + + ++ G TPL AA +V ++L R
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 76.2 bits (179), Expect = 4e-13
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ AGH + K L++ A VN + TPL A G ++VK L+ + A+ +
Sbjct: 439 TPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNL 498
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
A +T L IAA +G+++ V LL+ A G T LH AA+ G V LL+
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Query: 227 GA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
A +NG+TPL A +V++L R + A Y L + A +
Sbjct: 559 DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA-AKQNQVEV 617
Query: 286 LRMAYQY 292
R QY
Sbjct: 618 ARSLLQY 624
Score = 74.1 bits (174), Expect = 1e-12
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR+G ILL+ P+ +T+ G + + A+ HL V+
Sbjct: 274 TPLHCAARNGHVRISEILLDH-GAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 322
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+++ T TPL A G + K L+ GA + T L IA K
Sbjct: 323 LLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 382
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++ V++ LL +GA +D G T LH A+ GH +V +LL GA ++N TPL
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 242 CAAERARASVVEILAARPEVTRAEA 266
AA V + L A+A
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKA 467
Score = 72.9 bits (171), Expect = 3e-12
Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 21/231 (9%)
Query: 26 AARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFR 85
AAR+G T+ ALL EK+ + C TPL AA++G+ +LLE+
Sbjct: 510 AAREGHVETVLALL-EKEASQ--------ACMTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
P G G T L A +L IVK L+ G + TPL A
Sbjct: 561 HP---NAAGK--------NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 609
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
+ ++++ + L+++G + + T L +AA +G+ ++V LL A + G
Sbjct: 610 AKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGL 669
Query: 206 TALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A+ GH V L+ HG + T G TPL A+ +V+ L
Sbjct: 670 TPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Score = 71.3 bits (167), Expect = 1e-11
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+ AT+ A+ +G+L ++ G D+N + L A EG + +V L+
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEII 70
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K NT L IAA G +VV+ L++ GA V+ ++ G T L+ AA+ H VV L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVV 252
L++GA + E+G TPL A ++ +VV
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 70.5 bits (165), Expect = 2e-11
Identities = 62/207 (29%), Positives = 88/207 (42%), Gaps = 12/207 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G + LL+ K + + T L CA+ GH +VK
Sbjct: 439 TPLHMAARAGHTEVAKYLLQN-----------KAKVNAKAKDDQTPLHCAARIGHTNMVK 487
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+ N AT TPL A EG ++ V L+ A K T L +AA G
Sbjct: 488 LLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYG 547
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQ 241
+ V + LL+ A + G T LH A + +V LL G + NG TPL
Sbjct: 548 KVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLH 607
Query: 242 CAAERARASVVEILAARPEVTRAEAIE 268
AA++ + V L AE+++
Sbjct: 608 IAAKQNQVEVARSLLQYGGSANAESVQ 634
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ +L + + L+ GA VN + TPL A G + +V+ L+ GA I
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K T L AA G++ + + LLD GA + + G + +H AA+ H V LL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
+ A++ +T ++ +TPL AA V ++L + + A+ +
Sbjct: 326 QYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 372
Score = 69.3 bits (162), Expect = 4e-11
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++T TPL A L++ + L+ GA ++ + T L IA+ +G + +V+ LLD G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
A+++ + T LH AA GH + LLDHGA + +NG++P+ AA+ V
Sbjct: 263 AQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 254 IL 255
+L
Sbjct: 323 LL 324
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + + + L++ G N + TPL A EG ++V L+ A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L + A +G++ V L+ G VD G T LH A+ G+ +V LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H A + + G +PL AA++ +V +L
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 33.5 bits (73), Expect = 2.4
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 26/127 (20%)
Query: 507 RSGQTLLHLAADRNTPVDDFHTSDVCQFPCA------RTSRLLLDCGADVDAADMNRRTP 560
R ++ L DR ++ ++ CA R S +LLD GA + A N +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 561 LHVA-----------LISYQLTSDD------REQYNEAFCG---VVCELLSRGAHVDAMD 600
+H+A L+ Y DD + A CG V LL +GA ++
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 601 LDGITPL 607
L+G TPL
Sbjct: 369 LNGFTPL 375
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS G++ +V+ L+ GA + T+ TPL A G + I + L+ HGA I
Sbjct: 206 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 265
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + + +AA +LD V+ LL A +DD L T LH AA CGH V LL
Sbjct: 266 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 325
Query: 225 DHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
D GAK + NG TPL A ++ V+E+L
Sbjct: 326 DKGAKPNSRALNGFTPLHIACKKNHVRVMELL 357
Score = 94.7 bits (225), Expect = 9e-19
Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 1/161 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D G T L AS GHL IVK L++ GA N + V TPL A G ++ KYL+
Sbjct: 365 DAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 424
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++ A ++ K + T L AA G+ ++V+ LL++ A + G T LH AA GH
Sbjct: 425 QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVE 484
Query: 219 VVCSLLD-HGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
V +LL+ ++ + G TPL AA+ + V E+L R
Sbjct: 485 TVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 525
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/191 (33%), Positives = 93/191 (48%), Gaps = 12/191 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA G ++LL+K P + + G T L A H+ +++
Sbjct: 307 TPLHVAAHCGHHRVAKVLLDKGAKP-----------NSRALNGFTPLHIACKKNHVRVME 355
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+K GA ++ T + TPL A F G L IVK L++ GA + +N T L +AA G
Sbjct: 356 LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 415
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
+ +V ++LL + A+V+ +A T LH AA GH +V LL++ A L G TPL
Sbjct: 416 HTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLH 475
Query: 242 CAAERARASVV 252
AA V
Sbjct: 476 IAAREGHVETV 486
Score = 89.4 bits (212), Expect = 4e-17
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V LLEK C+ +G T L A+ G + + +
Sbjct: 472 TPLHIAAREGHVETVLALLEKEASQACMTKKGF-----------TPLHVAAKYGKVRVAE 520
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A N A + TPL A LDIVK L+ G H T L IAA +
Sbjct: 521 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQN 580
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++V + LL G + ++ G T LH AA+ GHA +V LL A L N++G+TPL
Sbjct: 581 QVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH 640
Query: 242 CAAERARASVVEIL 255
A+ V ++L
Sbjct: 641 LVAQEGHVPVADVL 654
Score = 88.2 bits (209), Expect = 8e-17
Identities = 67/197 (34%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G VR+LL++ +ET+ DE T L CA+ GH+ I +
Sbjct: 208 TPLHIASRRGNVIMVRLLLDRGAQ---IETKTK---DEL-----TPLHCAARNGHVRISE 256
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA + T+ +P+ A LD V+ L+++ A+I + T L +AA+ G
Sbjct: 257 ILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCG 316
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD GA+ + RAL G T LH A + H V+ LL GA + E+G+TPL
Sbjct: 317 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLH 376
Query: 242 CAAERARASVVEILAAR 258
A+ +V+ L R
Sbjct: 377 VASFMGHLPIVKNLLQR 393
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 1/160 (0%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
+ D+ ++ T L A+ GH + K L+ GA N TPL AC + + +++
Sbjct: 297 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMEL 356
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
L++ GA I + T L +A++ G+L +V+ LL GA + + T LH AA GH
Sbjct: 357 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 416
Query: 217 AAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEIL 255
V LL + AK+ ++ TPL CAA ++V++L
Sbjct: 417 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 456
Score = 81.8 bits (193), Expect = 7e-15
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G T L A+ GH +V L+ A+ N ++ TPL EG + + L++HG
Sbjct: 600 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 659
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L +A++ G + +V+FLL A V+ + G + LH AA+ GH +V
Sbjct: 660 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 719
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL +GA + +G TPL A SV ++L
Sbjct: 720 LLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 753
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V++LLE P T G T L A+ GH+ V
Sbjct: 439 TPLHCAARIGHTNMVKLLLENNANPNLATTAGH-----------TPLHIAAREGHVETVL 487
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A T+ TPL A G++ + + L+ A + A K T L +A +
Sbjct: 488 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 547
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
LD+V+ LL G A G T LH AA+ V SLL +G + G+TPL
Sbjct: 548 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLH 607
Query: 242 CAAERARASVVEILAAR 258
AA+ A +V +L ++
Sbjct: 608 LAAQEGHAEMVALLLSK 624
Score = 76.2 bits (179), Expect = 4e-13
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ AGH + K L++ A VN + TPL A G ++VK L+ + A+ +
Sbjct: 406 TPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNL 465
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
A +T L IAA +G+++ V LL+ A G T LH AA+ G V LL+
Sbjct: 466 ATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 525
Query: 227 GA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
A +NG+TPL A +V++L R + A Y L + A +
Sbjct: 526 DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA-AKQNQVEV 584
Query: 286 LRMAYQY 292
R QY
Sbjct: 585 ARSLLQY 591
Score = 74.1 bits (174), Expect = 1e-12
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR+G ILL+ P+ +T+ G + + A+ HL V+
Sbjct: 241 TPLHCAARNGHVRISEILLDH-GAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 289
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+++ T TPL A G + K L+ GA + T L IA K
Sbjct: 290 LLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 349
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++ V++ LL +GA +D G T LH A+ GH +V +LL GA ++N TPL
Sbjct: 350 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 409
Query: 242 CAAERARASVVEILAARPEVTRAEA 266
AA V + L A+A
Sbjct: 410 MAARAGHTEVAKYLLQNKAKVNAKA 434
Score = 73.3 bits (172), Expect = 2e-12
Identities = 52/156 (33%), Positives = 75/156 (48%), Gaps = 5/156 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L+ A+ HL +VK L++ GA+ N AT TPL A +G ++V +L+ +G
Sbjct: 77 KGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 136
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K L IAA LL + D + G T LH AA + V L
Sbjct: 137 ----GKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLL 192
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
L+ GA + T +NG+TPL A+ R +V +L R
Sbjct: 193 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDR 228
Score = 72.9 bits (171), Expect = 3e-12
Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 21/231 (9%)
Query: 26 AARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFR 85
AAR+G T+ ALL EK+ + C TPL AA++G+ +LLE+
Sbjct: 477 AAREGHVETVLALL-EKEASQ--------ACMTKKGFTPLHVAAKYGKVRVAELLLERDA 527
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
P G G T L A +L IVK L+ G + TPL A
Sbjct: 528 HP---NAAGK--------NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 576
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
+ ++++ + L+++G + + T L +AA +G+ ++V LL A + G
Sbjct: 577 AKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGL 636
Query: 206 TALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A+ GH V L+ HG + T G TPL A+ +V+ L
Sbjct: 637 TPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 687
Score = 70.9 bits (166), Expect = 1e-11
Identities = 40/126 (31%), Positives = 72/126 (57%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+ AT+ A+ +G+L ++ G D+N + +T L A G+ ++V+ LV +GA+
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGAN 70
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ ++ T L +AA + +L+VV+FLL++GA + G T L A + GH VV L
Sbjct: 71 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 130
Query: 224 LDHGAK 229
+++G K
Sbjct: 131 INYGTK 136
Score = 70.5 bits (165), Expect = 2e-11
Identities = 62/207 (29%), Positives = 88/207 (42%), Gaps = 12/207 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G + LL+ K + + T L CA+ GH +VK
Sbjct: 406 TPLHMAARAGHTEVAKYLLQN-----------KAKVNAKAKDDQTPLHCAARIGHTNMVK 454
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+ N AT TPL A EG ++ V L+ A K T L +AA G
Sbjct: 455 LLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYG 514
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQ 241
+ V + LL+ A + G T LH A + +V LL G + NG TPL
Sbjct: 515 KVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLH 574
Query: 242 CAAERARASVVEILAARPEVTRAEAIE 268
AA++ + V L AE+++
Sbjct: 575 IAAKQNQVEVARSLLQYGGSANAESVQ 601
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ +L + + L+ GA VN + TPL A G + +V+ L+ GA I
Sbjct: 173 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 232
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K T L AA G++ + + LLD GA + + G + +H AA+ H V LL
Sbjct: 233 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 292
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
+ A++ +T ++ +TPL AA V ++L + + A+ +
Sbjct: 293 QYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 339
Score = 69.3 bits (162), Expect = 4e-11
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++T TPL A L++ + L+ GA ++ + T L IA+ +G + +V+ LLD G
Sbjct: 170 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 229
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
A+++ + T LH AA GH + LLDHGA + +NG++P+ AA+ V
Sbjct: 230 AQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 289
Query: 254 IL 255
+L
Sbjct: 290 LL 291
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + + + L++ G N + TPL A EG ++V L+ A+
Sbjct: 569 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 628
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L + A +G++ V L+ G VD G T LH A+ G+ +V LL
Sbjct: 629 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 688
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H A + + G +PL AA++ +V +L
Sbjct: 689 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 720
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-L 231
T + AA G LD L +G ++ G TALH AA G VV L+++GA +
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNA 73
Query: 232 TNENGMTPLQCAAERARASVVEIL 255
++ G TPL AA+ VV+ L
Sbjct: 74 QSQKGFTPLYMAAQENHLEVVKFL 97
Score = 33.5 bits (73), Expect = 2.4
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 26/127 (20%)
Query: 507 RSGQTLLHLAADRNTPVDDFHTSDVCQFPCA------RTSRLLLDCGADVDAADMNRRTP 560
R ++ L DR ++ ++ CA R S +LLD GA + A N +P
Sbjct: 216 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 275
Query: 561 LHVA-----------LISYQLTSDD------REQYNEAFCG---VVCELLSRGAHVDAMD 600
+H+A L+ Y DD + A CG V LL +GA ++
Sbjct: 276 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 335
Query: 601 LDGITPL 607
L+G TPL
Sbjct: 336 LNGFTPL 342
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS G++ +V+ L+ GA + T+ TPL A G + I + L+ HGA I
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + + +AA +LD V+ LL A +DD L T LH AA CGH V LL
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 358
Query: 225 DHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
D GAK + NG TPL A ++ V+E+L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELL 390
Score = 94.7 bits (225), Expect = 9e-19
Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 1/161 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D G T L AS GHL IVK L++ GA N + V TPL A G ++ KYL+
Sbjct: 398 DAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++ A ++ K + T L AA G+ ++V+ LL++ A + G T LH AA GH
Sbjct: 458 QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVE 517
Query: 219 VVCSLLD-HGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
V +LL+ ++ + G TPL AA+ + V E+L R
Sbjct: 518 TVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/191 (33%), Positives = 93/191 (48%), Gaps = 12/191 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA G ++LL+K P + + G T L A H+ +++
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKP-----------NSRALNGFTPLHIACKKNHVRVME 388
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+K GA ++ T + TPL A F G L IVK L++ GA + +N T L +AA G
Sbjct: 389 LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 448
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
+ +V ++LL + A+V+ +A T LH AA GH +V LL++ A L G TPL
Sbjct: 449 HTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLH 508
Query: 242 CAAERARASVV 252
AA V
Sbjct: 509 IAAREGHVETV 519
Score = 89.4 bits (212), Expect = 4e-17
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V LLEK C+ +G T L A+ G + + +
Sbjct: 505 TPLHIAAREGHVETVLALLEKEASQACMTKKGF-----------TPLHVAAKYGKVRVAE 553
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A N A + TPL A LDIVK L+ G H T L IAA +
Sbjct: 554 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQN 613
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++V + LL G + ++ G T LH AA+ GHA +V LL A L N++G+TPL
Sbjct: 614 QVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH 673
Query: 242 CAAERARASVVEIL 255
A+ V ++L
Sbjct: 674 LVAQEGHVPVADVL 687
Score = 88.2 bits (209), Expect = 8e-17
Identities = 67/197 (34%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G VR+LL++ +ET+ DE T L CA+ GH+ I +
Sbjct: 241 TPLHIASRRGNVIMVRLLLDRGAQ---IETKTK---DEL-----TPLHCAARNGHVRISE 289
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA + T+ +P+ A LD V+ L+++ A+I + T L +AA+ G
Sbjct: 290 ILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCG 349
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD GA+ + RAL G T LH A + H V+ LL GA + E+G+TPL
Sbjct: 350 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLH 409
Query: 242 CAAERARASVVEILAAR 258
A+ +V+ L R
Sbjct: 410 VASFMGHLPIVKNLLQR 426
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 1/160 (0%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
+ D+ ++ T L A+ GH + K L+ GA N TPL AC + + +++
Sbjct: 330 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMEL 389
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
L++ GA I + T L +A++ G+L +V+ LL GA + + T LH AA GH
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 217 AAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEIL 255
V LL + AK+ ++ TPL CAA ++V++L
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 81.8 bits (193), Expect = 7e-15
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G T L A+ GH +V L+ A+ N ++ TPL EG + + L++HG
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 692
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L +A++ G + +V+FLL A V+ + G + LH AA+ GH +V
Sbjct: 693 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 752
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL +GA + +G TPL A SV ++L
Sbjct: 753 LLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V++LLE P T G T L A+ GH+ V
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGH-----------TPLHIAAREGHVETVL 520
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A T+ TPL A G++ + + L+ A + A K T L +A +
Sbjct: 521 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 580
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
LD+V+ LL G A G T LH AA+ V SLL +G + G+TPL
Sbjct: 581 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLH 640
Query: 242 CAAERARASVVEILAAR 258
AA+ A +V +L ++
Sbjct: 641 LAAQEGHAEMVALLLSK 657
Score = 77.8 bits (183), Expect = 1e-13
Identities = 66/220 (30%), Positives = 111/220 (50%), Gaps = 19/220 (8%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
+K D + + ++I+ C+ +G+ L + +EG V++++E + LET T K
Sbjct: 26 DKALDHLRNGVDINTCNQNGLNGLHLAS-----KEGHVKMVVELLHKEIILET--TTK-- 76
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL A+ AG +V+ LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 77 ----KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 132
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA+ + A + T L +A +G+ +VV L++ G + R ALH AA
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVR----LPALHIAARNDDTRT 188
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
LL + + ++ G TPL AA +V ++L R
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 76.2 bits (179), Expect = 4e-13
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ AGH + K L++ A VN + TPL A G ++VK L+ + A+ +
Sbjct: 439 TPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNL 498
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
A +T L IAA +G+++ V LL+ A G T LH AA+ G V LL+
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 558
Query: 227 GA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
A +NG+TPL A +V++L R + A Y L + A +
Sbjct: 559 DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA-AKQNQVEV 617
Query: 286 LRMAYQY 292
R QY
Sbjct: 618 ARSLLQY 624
Score = 74.1 bits (174), Expect = 1e-12
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR+G ILL+ P+ +T+ G + + A+ HL V+
Sbjct: 274 TPLHCAARNGHVRISEILLDH-GAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 322
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+++ T TPL A G + K L+ GA + T L IA K
Sbjct: 323 LLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 382
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++ V++ LL +GA +D G T LH A+ GH +V +LL GA ++N TPL
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 242 CAAERARASVVEILAARPEVTRAEA 266
AA V + L A+A
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKA 467
Score = 72.9 bits (171), Expect = 3e-12
Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 21/231 (9%)
Query: 26 AARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFR 85
AAR+G T+ ALL EK+ + C TPL AA++G+ +LLE+
Sbjct: 510 AAREGHVETVLALL-EKEASQ--------ACMTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
P G G T L A +L IVK L+ G + TPL A
Sbjct: 561 HP---NAAGK--------NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 609
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
+ ++++ + L+++G + + T L +AA +G+ ++V LL A + G
Sbjct: 610 AKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGL 669
Query: 206 TALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A+ GH V L+ HG + T G TPL A+ +V+ L
Sbjct: 670 TPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 720
Score = 71.3 bits (167), Expect = 1e-11
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+ AT+ A+ +G+L ++ G D+N + L A EG + +V L+
Sbjct: 11 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEII 70
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K NT L IAA G +VV+ L++ GA V+ ++ G T L+ AA+ H VV L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVV 252
L++GA + E+G TPL A ++ +VV
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 70.5 bits (165), Expect = 2e-11
Identities = 62/207 (29%), Positives = 88/207 (42%), Gaps = 12/207 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G + LL+ K + + T L CA+ GH +VK
Sbjct: 439 TPLHMAARAGHTEVAKYLLQN-----------KAKVNAKAKDDQTPLHCAARIGHTNMVK 487
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+ N AT TPL A EG ++ V L+ A K T L +AA G
Sbjct: 488 LLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYG 547
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQ 241
+ V + LL+ A + G T LH A + +V LL G + NG TPL
Sbjct: 548 KVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLH 607
Query: 242 CAAERARASVVEILAARPEVTRAEAIE 268
AA++ + V L AE+++
Sbjct: 608 IAAKQNQVEVARSLLQYGGSANAESVQ 634
Score = 68.9 bits (161), Expect = 5e-11
Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ +L + + L+ G+ VN + TPL A G + +V+ L+ GA I
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K T L AA G++ + + LLD GA + + G + +H AA+ H V LL
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
+ A++ +T ++ +TPL AA V ++L + + A+ +
Sbjct: 326 QYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 372
Score = 68.1 bits (159), Expect = 9e-11
Identities = 39/122 (31%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++T TPL A L++ + L+ G+ ++ + T L IA+ +G + +V+ LLD G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
A+++ + T LH AA GH + LLDHGA + +NG++P+ AA+ V
Sbjct: 263 AQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 322
Query: 254 IL 255
+L
Sbjct: 323 LL 324
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + + + L++ G N + TPL A EG ++V L+ A+
Sbjct: 602 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 661
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L + A +G++ V L+ G VD G T LH A+ G+ +V LL
Sbjct: 662 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 721
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H A + + G +PL AA++ +V +L
Sbjct: 722 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Score = 33.5 bits (73), Expect = 2.4
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 26/127 (20%)
Query: 507 RSGQTLLHLAADRNTPVDDFHTSDVCQFPCA------RTSRLLLDCGADVDAADMNRRTP 560
R ++ L DR ++ ++ CA R S +LLD GA + A N +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 561 LHVA-----------LISYQLTSDD------REQYNEAFCG---VVCELLSRGAHVDAMD 600
+H+A L+ Y DD + A CG V LL +GA ++
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 601 LDGITPL 607
L+G TPL
Sbjct: 369 LNGFTPL 375
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH+ +V L+ GA++N + L A + G LD+V L+ HGA++
Sbjct: 140 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 199
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L AA G ++VV+ LL+ G +D+ + G TALH A G AVV L+
Sbjct: 200 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 259
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D+GA + N NG TPL AA ++ +E+L
Sbjct: 260 DYGANVNQPNNNGFTPLHFAAASTHGALCLELL 292
Score = 92.7 bits (220), Expect = 4e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GHL +V L+ GA+V + TPL AA G++++VK+L+ G +I +
Sbjct: 176 ALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 235
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L IA Y G VV L+D GA V+ G T LHFAA H A+ LL ++
Sbjct: 236 NVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNN 295
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA + + +++G +PL A R
Sbjct: 296 GADVNIQSKDGKSPLHMTAVHGR 318
Score = 71.7 bits (168), Expect = 8e-12
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+K ADVN + TPL A + + ++ + ++ +++ T L AA
Sbjct: 90 VQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAAL 149
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTP 239
G++++V LL GA ++ ALH+AA GH VV L++HGA++ ++ G TP
Sbjct: 150 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 209
Query: 240 LQCAAERARASVVEIL 255
L AA + +VV+ L
Sbjct: 210 LHAAASNGQINVVKHL 225
Score = 70.5 bits (165), Expect = 2e-11
Identities = 58/175 (33%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G+ V+ LL V+ DE + G TAL A
Sbjct: 201 CKDKKGYTPLHAAASNGQINVVKHLLNL-----------GVEIDEINVYGNTALHIACYN 249
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G A+V L+ GA+VN TPL AA G L ++ LV +GAD++ +K +
Sbjct: 250 GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL-CLELLVNNGADVNIQSKDGKS 308
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
L + A G Q L+ +G +D G T LH AA GH ++ +L+ GA
Sbjct: 309 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 363
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ VN + R T L A G +++V L+ GA+I+ +K + L AAY G+LDVV
Sbjct: 131 SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVA 190
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L++ GA V + G T LH AA G VV LL+ G ++ N G T L A
Sbjct: 191 LLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 250
Query: 248 RASVVEIL 255
+ +VV L
Sbjct: 251 QDAVVNEL 258
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/154 (26%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ G + +VK L+ G +++ +T L AC+ G+ +V L+ +GA+
Sbjct: 205 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 264
Query: 164 IHKANKYNNTCLMIAAYKGYLDV-VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ N T L AA + + ++ L+++GA V+ ++ G + LH A G +
Sbjct: 265 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 324
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L+ +G ++ +++G TPL AA ++ L
Sbjct: 325 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 358
Score = 62.5 bits (145), Expect = 5e-09
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL+ A G +R+L+ K TE D E T L A+ G I++
Sbjct: 11 PLVQAIFSGDPEEIRMLIHK--------TEDVNTLDS---EKRTPLHVAAFLGDAEIIEL 59
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L+ +GA VN TPL A + V+ L++H AD++ +K T L +AA
Sbjct: 60 LILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKA 119
Query: 184 LDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPL 240
+ + ++ S V DR G TALH AA GH +V LL GA + ++ L
Sbjct: 120 VKCAEVIIPLLSSVNVSDRG--GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRAL 177
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
AA VV +L + + Y L A+ +N
Sbjct: 178 HWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 216
Score = 54.0 bits (124), Expect = 2e-06
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
Query: 137 TVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGAR 196
T PL A F G + ++ L+ D++ + T L +AA+ G ++++ L+ SGAR
Sbjct: 7 TDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGAR 66
Query: 197 VDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
V+ + T LH A V L+ H A + ++N TPL AA E++
Sbjct: 67 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 126
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH+ +V L+ GA++N + L A + G LD+V L+ HGA++
Sbjct: 79 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 138
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L AA G ++VV+ LL+ G +D+ + G TALH A G AVV L+
Sbjct: 139 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 198
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D+GA + N NG TPL AA ++ +E+L
Sbjct: 199 DYGANVNQPNNNGFTPLHFAAASTHGALCLELL 231
Score = 92.7 bits (220), Expect = 4e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GHL +V L+ GA+V + TPL AA G++++VK+L+ G +I +
Sbjct: 115 ALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 174
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L IA Y G VV L+D GA V+ G T LHFAA H A+ LL ++
Sbjct: 175 NVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNN 234
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA + + +++G +PL A R
Sbjct: 235 GADVNIQSKDGKSPLHMTAVHGR 257
Score = 71.7 bits (168), Expect = 8e-12
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+K ADVN + TPL A + + ++ + ++ +++ T L AA
Sbjct: 29 VQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAAL 88
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTP 239
G++++V LL GA ++ ALH+AA GH VV L++HGA++ ++ G TP
Sbjct: 89 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 148
Query: 240 LQCAAERARASVVEIL 255
L AA + +VV+ L
Sbjct: 149 LHAAASNGQINVVKHL 164
Score = 70.5 bits (165), Expect = 2e-11
Identities = 58/175 (33%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G+ V+ LL V+ DE + G TAL A
Sbjct: 140 CKDKKGYTPLHAAASNGQINVVKHLLNL-----------GVEIDEINVYGNTALHIACYN 188
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G A+V L+ GA+VN TPL AA G L ++ LV +GAD++ +K +
Sbjct: 189 GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL-CLELLVNNGADVNIQSKDGKS 247
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
L + A G Q L+ +G +D G T LH AA GH ++ +L+ GA
Sbjct: 248 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 302
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ VN + R T L A G +++V L+ GA+I+ +K + L AAY G+LDVV
Sbjct: 70 SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVA 129
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L++ GA V + G T LH AA G VV LL+ G ++ N G T L A
Sbjct: 130 LLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 189
Query: 248 RASVVEIL 255
+ +VV L
Sbjct: 190 QDAVVNEL 197
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/154 (26%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ G + +VK L+ G +++ +T L AC+ G+ +V L+ +GA+
Sbjct: 144 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 203
Query: 164 IHKANKYNNTCLMIAAYKGYLDV-VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ N T L AA + + ++ L+++GA V+ ++ G + LH A G +
Sbjct: 204 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 263
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L+ +G ++ +++G TPL AA ++ L
Sbjct: 264 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 297
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/156 (29%), Positives = 68/156 (43%), Gaps = 5/156 (3%)
Query: 127 AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDV 186
+GA VN TPL A + V+ L++H AD++ +K T L +AA +
Sbjct: 2 SGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKC 61
Query: 187 VQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCA 243
+ ++ S V DR G TALH AA GH +V LL GA + ++ L A
Sbjct: 62 AEVIIPLLSSVNVSDRG--GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWA 119
Query: 244 AERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
A VV +L + + Y L A+ +N
Sbjct: 120 AYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 155
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH+ +V L+ GA++N + L A + G LD+V L+ HGA++
Sbjct: 140 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 199
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L AA G ++VV+ LL+ G +D+ + G TALH A G AVV L+
Sbjct: 200 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 259
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D+GA + N NG TPL AA ++ +E+L
Sbjct: 260 DYGANVNQPNNNGFTPLHFAAASTHGALCLELL 292
Score = 92.7 bits (220), Expect = 4e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GHL +V L+ GA+V + TPL AA G++++VK+L+ G +I +
Sbjct: 176 ALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 235
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L IA Y G VV L+D GA V+ G T LHFAA H A+ LL ++
Sbjct: 236 NVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNN 295
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA + + +++G +PL A R
Sbjct: 296 GADVNIQSKDGKSPLHMTAVHGR 318
Score = 72.9 bits (171), Expect = 3e-12
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 15/197 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G+ V+ LL V+ DE + G TAL A
Sbjct: 201 CKDKKGYTPLHAAASNGQINVVKHLLNL-----------GVEIDEINVYGNTALHIACYN 249
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G A+V L+ GA+VN TPL AA G L ++ LV +GAD++ +K +
Sbjct: 250 GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL-CLELLVNNGADVNIQSKDGKS 308
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML-T 232
L + A G Q L+ +G +D G T LH AA GH ++ +L+ GA
Sbjct: 309 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKC 368
Query: 233 NENGMTPLQCAAERARA 249
+ M PL AA A +
Sbjct: 369 GIHSMFPLHLAALNAHS 385
Score = 71.7 bits (168), Expect = 8e-12
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+K ADVN + TPL A + + ++ + ++ +++ T L AA
Sbjct: 90 VQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAAL 149
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTP 239
G++++V LL GA ++ ALH+AA GH VV L++HGA++ ++ G TP
Sbjct: 150 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 209
Query: 240 LQCAAERARASVVEIL 255
L AA + +VV+ L
Sbjct: 210 LHAAASNGQINVVKHL 225
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/142 (31%), Positives = 68/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH ++ L+ +GAD PL A D + L+ G +
Sbjct: 338 DGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFE 397
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
I +K+ TCL AA G ++ ++ L SGA + CG T LH+AA H + +L
Sbjct: 398 IDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 457
Query: 224 LDHGAKM-LTNENGMTPLQCAA 244
+ GA + T++ G T L AA
Sbjct: 458 VTTGANVNETDDWGRTALHYAA 479
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ VN + R T L A G +++V L+ GA+I+ +K + L AAY G+LDVV
Sbjct: 131 SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVA 190
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L++ GA V + G T LH AA G VV LL+ G ++ N G T L A
Sbjct: 191 LLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 250
Query: 248 RASVVEIL 255
+ +VV L
Sbjct: 251 QDAVVNEL 258
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/154 (26%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ G + +VK L+ G +++ +T L AC+ G+ +V L+ +GA+
Sbjct: 205 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 264
Query: 164 IHKANKYNNTCLMIAAYKGYLDV-VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ N T L AA + + ++ L+++GA V+ ++ G + LH A G +
Sbjct: 265 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 324
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L+ +G ++ +++G TPL AA ++ L
Sbjct: 325 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 358
Score = 62.5 bits (145), Expect = 5e-09
Identities = 63/219 (28%), Positives = 93/219 (42%), Gaps = 16/219 (7%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL+ A G +R+L+ K TE D E T L A+ G I++
Sbjct: 11 PLVQAIFSGDPEEIRMLIHK--------TEDVNTLDS---EKRTPLHVAAFLGDAEIIEL 59
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L+ +GA VN TPL A + V+ L++H AD++ +K T L +AA
Sbjct: 60 LILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKA 119
Query: 184 LDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPL 240
+ + ++ S V DR G TALH AA GH +V LL GA + ++ L
Sbjct: 120 VKCAEVIIPLLSSVNVSDRG--GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRAL 177
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
AA VV +L + + Y L A+ +N
Sbjct: 178 HWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 216
Score = 62.5 bits (145), Expect = 5e-09
Identities = 50/156 (32%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 105 GATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L A+ + H A+ ++ LV GADVN ++ +PL GR + L+++G +
Sbjct: 272 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 331
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA---LHFAAECGHAAVV 220
I +K NT L +AA G+ ++ L+ SGA D A CG + LH AA H+
Sbjct: 332 IDCVDKDGNTPLHVAARYGHELLINTLITSGA---DTAKCGIHSMFPLHLAALNAHSDCC 388
Query: 221 CSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G ++ T + G T L AA +++L
Sbjct: 389 RKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 424
Score = 59.3 bits (137), Expect = 4e-08
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G + L + G + L++ G +++ + +TPL A G ++ L+ GAD
Sbjct: 305 DGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 364
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K ++ L +AA + D + LL SG +D G T LH AA G+ + L
Sbjct: 365 TAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 424
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
GA + G TPL AA +E L
Sbjct: 425 QSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 457
Score = 54.0 bits (124), Expect = 2e-06
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
Query: 137 TVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGAR 196
T PL A F G + ++ L+ D++ + T L +AA+ G ++++ L+ SGAR
Sbjct: 7 TDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGAR 66
Query: 197 VDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
V+ + T LH A V L+ H A + ++N TPL AA E++
Sbjct: 67 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 126
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH+ +V L+ GA++N + L A + G LD+V L+ HGA++
Sbjct: 115 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 174
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L AA G ++VV+ LL+ G +D+ + G TALH A G AVV L+
Sbjct: 175 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 234
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D+GA + N NG TPL AA ++ +E+L
Sbjct: 235 DYGANVNQPNNNGFTPLHFAAASTHGALCLELL 267
Score = 92.7 bits (220), Expect = 4e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GHL +V L+ GA+V + TPL AA G++++VK+L+ G +I +
Sbjct: 151 ALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 210
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L IA Y G VV L+D GA V+ G T LHFAA H A+ LL ++
Sbjct: 211 NVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNN 270
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA + + +++G +PL A R
Sbjct: 271 GADVNIQSKDGKSPLHMTAVHGR 293
Score = 71.7 bits (168), Expect = 8e-12
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+K ADVN + TPL A + + ++ + ++ +++ T L AA
Sbjct: 65 VQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAAL 124
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTP 239
G++++V LL GA ++ ALH+AA GH VV L++HGA++ ++ G TP
Sbjct: 125 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 184
Query: 240 LQCAAERARASVVEIL 255
L AA + +VV+ L
Sbjct: 185 LHAAASNGQINVVKHL 200
Score = 71.3 bits (167), Expect = 1e-11
Identities = 64/197 (32%), Positives = 88/197 (44%), Gaps = 15/197 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G+ V+ LL V+ DE + G TAL A
Sbjct: 176 CKDKKGYTPLHAAASNGQINVVKHLLNL-----------GVEIDEINVYGNTALHIACYN 224
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G A+V L+ GA+VN TPL AA G L ++ LV +GAD++ +K +
Sbjct: 225 GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL-CLELLVNNGADVNIQSKDGKS 283
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML-T 232
L + A G Q L+ +G +D G T LH AA GH ++ +L GA
Sbjct: 284 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKC 343
Query: 233 NENGMTPLQCAAERARA 249
+ M PL AA A +
Sbjct: 344 GIHSMFPLHLAALNAHS 360
Score = 70.9 bits (166), Expect = 1e-11
Identities = 64/199 (32%), Positives = 90/199 (45%), Gaps = 20/199 (10%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G +PL AA +G A+ +LL+ V L+ DE +G TAL A+ GH
Sbjct: 540 GATKSPLHLAAYNGHHQALEVLLQSL---VDLDIR-----DE---KGRTALDLAAFKGHT 588
Query: 119 AIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLVR-----HGADIHKANKYNN 172
V+ L+ GA + T TPL A+ G ++ L+ D+ A
Sbjct: 589 ECVEALINPGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAK--GQ 646
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T LM+A G++D V LL+ A VD + G TALH GH V LL+ +L
Sbjct: 647 TPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILC 706
Query: 233 NEN-GMTPLQCAAERARAS 250
++ G TPL AA R A+
Sbjct: 707 KDSRGRTPLHYAAARGHAT 725
Score = 68.5 bits (160), Expect = 7e-11
Identities = 45/142 (31%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH ++ L +GAD PL A D + L+ G +
Sbjct: 313 DGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFE 372
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
I +K+ TCL AA G ++ ++ L SGA + CG T LH+AA H + +L
Sbjct: 373 IDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 432
Query: 224 LDHGAKM-LTNENGMTPLQCAA 244
+ GA + T++ G T L AA
Sbjct: 433 VTTGANVNETDDWGRTALHYAA 454
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ VN + R T L A G +++V L+ GA+I+ +K + L AAY G+LDVV
Sbjct: 106 SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVA 165
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L++ GA V + G T LH AA G VV LL+ G ++ N G T L A
Sbjct: 166 LLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 225
Query: 248 RASVVEIL 255
+ +VV L
Sbjct: 226 QDAVVNEL 233
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/154 (26%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ G + +VK L+ G +++ +T L AC+ G+ +V L+ +GA+
Sbjct: 180 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 239
Query: 164 IHKANKYNNTCLMIAAYKGYLDV-VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ N T L AA + + ++ L+++GA V+ ++ G + LH A G +
Sbjct: 240 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 299
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L+ +G ++ +++G TPL AA ++ L
Sbjct: 300 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 333
Score = 61.3 bits (142), Expect = 1e-08
Identities = 53/179 (29%), Positives = 79/179 (44%), Gaps = 5/179 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 15 EKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSAD 74
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L +AA + + ++ S V DR G TALH AA GH +V
Sbjct: 75 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG--GRTALHHAALNGHVEMVN 132
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
LL GA + ++ L AA VV +L + + Y L A+ +N
Sbjct: 133 LLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 191
Score = 60.9 bits (141), Expect = 1e-08
Identities = 50/156 (32%), Positives = 76/156 (48%), Gaps = 8/156 (5%)
Query: 105 GATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L A+ + H A+ ++ LV GADVN ++ +PL GR + L+++G +
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA---LHFAAECGHAAVV 220
I +K NT L +AA G+ ++ L SGA D A CG + LH AA H+
Sbjct: 307 IDCVDKDGNTPLHVAARYGHELLINTLRTSGA---DTAKCGIHSMFPLHLAALNAHSDCC 363
Query: 221 CSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G ++ T + G T L AA +++L
Sbjct: 364 RKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Score = 56.8 bits (131), Expect = 2e-07
Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G + L + G + L++ G +++ + +TPL A G ++ L GAD
Sbjct: 280 DGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGAD 339
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K ++ L +AA + D + LL SG +D G T LH AA G+ + L
Sbjct: 340 TAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
GA + G TPL AA +E L
Sbjct: 400 QSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 432
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/178 (29%), Positives = 76/178 (42%), Gaps = 20/178 (11%)
Query: 54 DVC-SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCA 112
D C D TPL A +G E + +LLE+ C F +++ T L CA
Sbjct: 739 DCCFKDNQGYTPLHWACYNGNENCIEVLLEQ----KC--------FRKFIGNPFTPLHCA 786
Query: 113 SGAGHLAIVKRLVKA--GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
H L+ A + V+ TPLRAA F ++ ++ L+RH A ++ +
Sbjct: 787 IINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNS 846
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
T LM+AA G V L++S V D+ L T LH A GH +LD
Sbjct: 847 GKTALMMAAENGQAGAVDILVNSAQADLTVKDKDL--NTPLHLACSKGHEKCALLILD 902
Score = 48.4 bits (110), Expect = 8e-05
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL A G +D V L+ A++ + T L G+ + VQ LL+ +
Sbjct: 647 TPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILC 706
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAK----MLTNENGMTPLQCAAERARASVVEIL 255
+ G T LH+AA GHA + LL + G TPL A + +E+L
Sbjct: 707 KDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVL 766
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/160 (25%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVK---AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
EG ++ A+ GH ++ L++ +G + + + T S PL A + G ++ L++
Sbjct: 506 EGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKS-PLHLAAYNGHHQALEVLLQS 564
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR-ALCGATALHFAAECGHAAV 219
D+ ++ T L +AA+KG+ + V+ L++ GA + + + T LH + GH
Sbjct: 565 LVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASIFVKDNVTKRTPLHASVINGHTLC 624
Query: 220 VCSLLDHG----AKMLTNENGMTPLQCAAERARASVVEIL 255
+ LL+ A + + G TPL A V +L
Sbjct: 625 LRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLL 664
Score = 42.7 bits (96), Expect = 0.004
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L+ DVN TPL A F G +I++ L+ GA ++ + T L A
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAA---ECGHAAVVCSLLDHGAKMLTNENGMTPL 240
+ VQ L+ A V+ R T LH AA A V+ LL + +++ G T L
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLL--SSVNVSDRGGRTAL 119
Query: 241 QCAAERARASVVEILAAR 258
AA +V +L A+
Sbjct: 120 HHAALNGHVEMVNLLLAK 137
Score = 36.7 bits (81), Expect = 0.26
Identities = 56/211 (26%), Positives = 82/211 (38%), Gaps = 23/211 (10%)
Query: 53 IDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCA 112
+DV D TPL+ A +G AV +LLEK E V D I G TAL
Sbjct: 638 VDV-KDAKGQTPLMLAVAYGHIDAVSLLLEK---------EANV--DTVDILGCTALHRG 685
Query: 113 SGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG---ADIHKANK 169
GH V+ L++ + TPL A G + L++ D +
Sbjct: 686 IMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDN 745
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGH---AAVVCSLL 224
T L A Y G + ++ LL+ R G T LH A H A+++ +
Sbjct: 746 QGYTPLHWACYNGNENCIEVLLEQKC---FRKFIGNPFTPLHCAIINDHGNCASLLLGAI 802
Query: 225 DHGAKMLTNENGMTPLQCAAERARASVVEIL 255
D ++ G TPL+ AA +++L
Sbjct: 803 DSSIVSCRDDKGRTPLRAAAFADHVECLQLL 833
Score = 34.3 bits (75), Expect = 1.4
Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ H ++ LV GA+VN T L A +D K ++ +
Sbjct: 413 GRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASD-MDRNKTIL---GNA 468
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
H ++ + + L ++FLL + A R G ++H+AA GH + LL
Sbjct: 469 HDNSEELERARELKEKEATL-CLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLL 527
Query: 225 DH-GAKMLTNENGMT--PLQCAAERARASVVEIL 255
+ + +++G T PL AA +E+L
Sbjct: 528 ERTNSGFEESDSGATKSPLHLAAYNGHHQALEVL 561
Score = 33.5 bits (73), Expect = 2.4
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L AA+ +++ +Q LL A V+ G TAL AAE G A V L++ LT
Sbjct: 816 TPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLT 875
Query: 233 --NENGMTPLQCAAER 246
+++ TPL A +
Sbjct: 876 VKDKDLNTPLHLACSK 891
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH+ +V L+ GA++N + L A + G LD+V L+ HGA++
Sbjct: 115 GRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEV 174
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K T L AA G ++VV+ LL+ G +D+ + G TALH A G AVV L+
Sbjct: 175 TCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELI 234
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASV-VEIL 255
D+GA + N NG TPL AA ++ +E+L
Sbjct: 235 DYGANVNQPNNNGFTPLHFAAASTHGALCLELL 267
Score = 92.7 bits (220), Expect = 4e-18
Identities = 56/143 (39%), Positives = 80/143 (55%), Gaps = 2/143 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GHL +V L+ GA+V + TPL AA G++++VK+L+ G +I +
Sbjct: 151 ALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 210
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL-DH 226
N Y NT L IA Y G VV L+D GA V+ G T LHFAA H A+ LL ++
Sbjct: 211 NVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNN 270
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA + + +++G +PL A R
Sbjct: 271 GADVNIQSKDGKSPLHMTAVHGR 293
Score = 72.9 bits (171), Expect = 3e-12
Identities = 64/197 (32%), Positives = 89/197 (45%), Gaps = 15/197 (7%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G+ V+ LL V+ DE + G TAL A
Sbjct: 176 CKDKKGYTPLHAAASNGQINVVKHLLNL-----------GVEIDEINVYGNTALHIACYN 224
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLR--AACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G A+V L+ GA+VN TPL AA G L ++ LV +GAD++ +K +
Sbjct: 225 GQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGAL-CLELLVNNGADVNIQSKDGKS 283
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML-T 232
L + A G Q L+ +G +D G T LH AA GH ++ +L+ GA
Sbjct: 284 PLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKC 343
Query: 233 NENGMTPLQCAAERARA 249
+ M PL AA A +
Sbjct: 344 GIHSMFPLHLAALNAHS 360
Score = 71.7 bits (168), Expect = 8e-12
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V+ L+K ADVN + TPL A + + ++ + ++ +++ T L AA
Sbjct: 65 VQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAAL 124
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTP 239
G++++V LL GA ++ ALH+AA GH VV L++HGA++ ++ G TP
Sbjct: 125 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 184
Query: 240 LQCAAERARASVVEIL 255
L AA + +VV+ L
Sbjct: 185 LHAAASNGQINVVKHL 200
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/142 (31%), Positives = 68/142 (47%), Gaps = 1/142 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH ++ L+ +GAD PL A D + L+ G +
Sbjct: 313 DGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFE 372
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
I +K+ TCL AA G ++ ++ L SGA + CG T LH+AA H + +L
Sbjct: 373 IDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 432
Query: 224 LDHGAKM-LTNENGMTPLQCAA 244
+ GA + T++ G T L AA
Sbjct: 433 VTTGANVNETDDWGRTALHYAA 454
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/128 (35%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ VN + R T L A G +++V L+ GA+I+ +K + L AAY G+LDVV
Sbjct: 106 SSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVA 165
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L++ GA V + G T LH AA G VV LL+ G ++ N G T L A
Sbjct: 166 LLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 225
Query: 248 RASVVEIL 255
+ +VV L
Sbjct: 226 QDAVVNEL 233
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/154 (26%), Positives = 80/154 (51%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ G + +VK L+ G +++ +T L AC+ G+ +V L+ +GA+
Sbjct: 180 KGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGAN 239
Query: 164 IHKANKYNNTCLMIAAYKGYLDV-VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ N T L AA + + ++ L+++GA V+ ++ G + LH A G +
Sbjct: 240 VNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQT 299
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L+ +G ++ +++G TPL AA ++ L
Sbjct: 300 LIQNGGEIDCVDKDGNTPLHVAARYGHELLINTL 333
Score = 62.5 bits (145), Expect = 5e-09
Identities = 50/156 (32%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 105 GATALWCASGAGHLAI-VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L A+ + H A+ ++ LV GADVN ++ +PL GR + L+++G +
Sbjct: 247 GFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGE 306
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA---LHFAAECGHAAVV 220
I +K NT L +AA G+ ++ L+ SGA D A CG + LH AA H+
Sbjct: 307 IDCVDKDGNTPLHVAARYGHELLINTLITSGA---DTAKCGIHSMFPLHLAALNAHSDCC 363
Query: 221 CSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
LL G ++ T + G T L AA +++L
Sbjct: 364 RKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Score = 61.3 bits (142), Expect = 1e-08
Identities = 53/179 (29%), Positives = 79/179 (44%), Gaps = 5/179 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L A+ G I++ L+ +GA VN TPL A + V+ L++H AD
Sbjct: 15 EKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSAD 74
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVC 221
++ +K T L +AA + + ++ S V DR G TALH AA GH +V
Sbjct: 75 VNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG--GRTALHHAALNGHVEMVN 132
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
LL GA + ++ L AA VV +L + + Y L A+ +N
Sbjct: 133 LLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASN 191
Score = 59.3 bits (137), Expect = 4e-08
Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G + L + G + L++ G +++ + +TPL A G ++ L+ GAD
Sbjct: 280 DGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 339
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
K ++ L +AA + D + LL SG +D G T LH AA G+ + L
Sbjct: 340 TAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLL 399
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
GA + G TPL AA +E L
Sbjct: 400 QSSGADFHKKDKCGRTPLHYAAANCHFHCIETL 432
Score = 42.7 bits (96), Expect = 0.004
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L+ DVN TPL A F G +I++ L+ GA ++ + T L A
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAA---ECGHAAVVCSLLDHGAKMLTNENGMTPL 240
+ VQ L+ A V+ R T LH AA A V+ LL + +++ G T L
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLL--SSVNVSDRGGRTAL 119
Query: 241 QCAAERARASVVEILAAR 258
AA +V +L A+
Sbjct: 120 HHAALNGHVEMVNLLLAK 137
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 95.5 bits (227), Expect = 5e-19
Identities = 58/152 (38%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS G++ +V+ L+ GA + T+ TPL A G + I + L+ HGA I
Sbjct: 274 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 333
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K + + +AA +LD V+ LL A +DD L T LH AA CGH V LL
Sbjct: 334 QAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLL 393
Query: 225 DHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
D GAK + NG TPL A ++ V+E+L
Sbjct: 394 DKGAKPNSRALNGFTPLHIACKKNHVRVMELL 425
Score = 94.7 bits (225), Expect = 9e-19
Identities = 57/161 (35%), Positives = 83/161 (51%), Gaps = 1/161 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D G T L AS GHL IVK L++ GA N + V TPL A G ++ KYL+
Sbjct: 433 DAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 492
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++ A ++ K + T L AA G+ ++V+ LL++ A + G T LH AA GH
Sbjct: 493 QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVE 552
Query: 219 VVCSLLD-HGAKMLTNENGMTPLQCAAERARASVVEILAAR 258
V +LL+ ++ + G TPL AA+ + V E+L R
Sbjct: 553 TVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 593
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/191 (33%), Positives = 93/191 (48%), Gaps = 12/191 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA G ++LL+K P + + G T L A H+ +++
Sbjct: 375 TPLHVAAHCGHHRVAKVLLDKGAKP-----------NSRALNGFTPLHIACKKNHVRVME 423
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+K GA ++ T + TPL A F G L IVK L++ GA + +N T L +AA G
Sbjct: 424 LLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 483
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
+ +V ++LL + A+V+ +A T LH AA GH +V LL++ A L G TPL
Sbjct: 484 HTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLH 543
Query: 242 CAAERARASVV 252
AA V
Sbjct: 544 IAAREGHVETV 554
Score = 89.4 bits (212), Expect = 4e-17
Identities = 65/194 (33%), Positives = 90/194 (46%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V LLEK C+ +G T L A+ G + + +
Sbjct: 540 TPLHIAAREGHVETVLALLEKEASQACMTKKGF-----------TPLHVAAKYGKVRVAE 588
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A N A + TPL A LDIVK L+ G H T L IAA +
Sbjct: 589 LLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQN 648
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++V + LL G + ++ G T LH AA+ GHA +V LL A L N++G+TPL
Sbjct: 649 QVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH 708
Query: 242 CAAERARASVVEIL 255
A+ V ++L
Sbjct: 709 LVAQEGHVPVADVL 722
Score = 88.2 bits (209), Expect = 8e-17
Identities = 67/197 (34%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A+R G VR+LL++ +ET+ DE T L CA+ GH+ I +
Sbjct: 276 TPLHIASRRGNVIMVRLLLDRGAQ---IETKTK---DEL-----TPLHCAARNGHVRISE 324
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA + T+ +P+ A LD V+ L+++ A+I + T L +AA+ G
Sbjct: 325 ILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCG 384
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+ V + LLD GA+ + RAL G T LH A + H V+ LL GA + E+G+TPL
Sbjct: 385 HHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLH 444
Query: 242 CAAERARASVVEILAAR 258
A+ +V+ L R
Sbjct: 445 VASFMGHLPIVKNLLQR 461
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/160 (31%), Positives = 81/160 (50%), Gaps = 1/160 (0%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
+ D+ ++ T L A+ GH + K L+ GA N TPL AC + + +++
Sbjct: 365 EIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMEL 424
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
L++ GA I + T L +A++ G+L +V+ LL GA + + T LH AA GH
Sbjct: 425 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 484
Query: 217 AAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEIL 255
V LL + AK+ ++ TPL CAA ++V++L
Sbjct: 485 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 524
Score = 81.8 bits (193), Expect = 7e-15
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G T L A+ GH +V L+ A+ N ++ TPL EG + + L++HG
Sbjct: 668 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 727
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L +A++ G + +V+FLL A V+ + G + LH AA+ GH +V
Sbjct: 728 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTL 787
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERARASVVEIL 255
LL +GA + +G TPL A SV ++L
Sbjct: 788 LLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 821
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G V++LLE P T G T L A+ GH+ V
Sbjct: 507 TPLHCAARIGHTNMVKLLLENNANPNLATTAGH-----------TPLHIAAREGHVETVL 555
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A T+ TPL A G++ + + L+ A + A K T L +A +
Sbjct: 556 ALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHN 615
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
LD+V+ LL G A G T LH AA+ V SLL +G + G+TPL
Sbjct: 616 NLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLH 675
Query: 242 CAAERARASVVEILAAR 258
AA+ A +V +L ++
Sbjct: 676 LAAQEGHAEMVALLLSK 692
Score = 77.8 bits (183), Expect = 1e-13
Identities = 66/220 (30%), Positives = 111/220 (50%), Gaps = 19/220 (8%)
Query: 41 EKKTDEIDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD 99
+K D + + ++I+ C+ +G+ L + +EG V++++E + LET T K
Sbjct: 61 DKALDHLRNGVDINTCNQNGLNGLHLAS-----KEGHVKMVVELLHKEIILET--TTK-- 111
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G TAL A+ AG +V+ LV GA+VN ++ TPL A E L++VK+L+
Sbjct: 112 ----KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLE 167
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
+GA+ + A + T L +A +G+ +VV L++ G + R ALH AA
Sbjct: 168 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVR----LPALHIAARNDDTRT 223
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
LL + + ++ G TPL AA +V ++L R
Sbjct: 224 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNR 263
Score = 76.2 bits (179), Expect = 4e-13
Identities = 58/187 (31%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ AGH + K L++ A VN + TPL A G ++VK L+ + A+ +
Sbjct: 474 TPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNL 533
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
A +T L IAA +G+++ V LL+ A G T LH AA+ G V LL+
Sbjct: 534 ATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER 593
Query: 227 GA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYC 285
A +NG+TPL A +V++L R + A Y L + A +
Sbjct: 594 DAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA-AKQNQVEV 652
Query: 286 LRMAYQY 292
R QY
Sbjct: 653 ARSLLQY 659
Score = 74.1 bits (174), Expect = 1e-12
Identities = 62/205 (30%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR+G ILL+ P+ +T+ G + + A+ HL V+
Sbjct: 309 TPLHCAARNGHVRISEILLDH-GAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 357
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+++ T TPL A G + K L+ GA + T L IA K
Sbjct: 358 LLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKN 417
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQ 241
++ V++ LL +GA +D G T LH A+ GH +V +LL GA ++N TPL
Sbjct: 418 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 477
Query: 242 CAAERARASVVEILAARPEVTRAEA 266
AA V + L A+A
Sbjct: 478 MAARAGHTEVAKYLLQNKAKVNAKA 502
Score = 72.9 bits (171), Expect = 3e-12
Identities = 66/231 (28%), Positives = 101/231 (43%), Gaps = 21/231 (9%)
Query: 26 AARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFR 85
AAR+G T+ ALL EK+ + C TPL AA++G+ +LLE+
Sbjct: 545 AAREGHVETVLALL-EKEASQ--------ACMTKKGFTPLHVAAKYGKVRVAELLLERDA 595
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
P G G T L A +L IVK L+ G + TPL A
Sbjct: 596 HP---NAAGK--------NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIA 644
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
+ ++++ + L+++G + + T L +AA +G+ ++V LL A + G
Sbjct: 645 AKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGL 704
Query: 206 TALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
T LH A+ GH V L+ HG + T G TPL A+ +V+ L
Sbjct: 705 TPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFL 755
Score = 71.3 bits (167), Expect = 1e-11
Identities = 48/150 (32%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+ AT+ A+ +G+L ++ G D+N + L A EG + +V L+
Sbjct: 46 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEII 105
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K NT L IAA G +VV+ L++ GA V+ ++ G T L+ AA+ H VV L
Sbjct: 106 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 165
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVV 252
L++GA + E+G TPL A ++ +VV
Sbjct: 166 LENGANQNVATEDGFTPLAVALQQGHENVV 195
Score = 70.5 bits (165), Expect = 2e-11
Identities = 62/207 (29%), Positives = 88/207 (42%), Gaps = 12/207 (5%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AAR G + LL+ K + + T L CA+ GH +VK
Sbjct: 474 TPLHMAARAGHTEVAKYLLQN-----------KAKVNAKAKDDQTPLHCAARIGHTNMVK 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A+ N AT TPL A EG ++ V L+ A K T L +AA G
Sbjct: 523 LLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYG 582
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQ 241
+ V + LL+ A + G T LH A + +V LL G + NG TPL
Sbjct: 583 KVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLH 642
Query: 242 CAAERARASVVEILAARPEVTRAEAIE 268
AA++ + V L AE+++
Sbjct: 643 IAAKQNQVEVARSLLQYGGSANAESVQ 669
Score = 70.1 bits (164), Expect = 2e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ +L + + L+ GA VN + TPL A G + +V+ L+ GA I
Sbjct: 241 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 300
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
K T L AA G++ + + LLD GA + + G + +H AA+ H V LL
Sbjct: 301 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 360
Query: 225 DHGAKM--LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
+ A++ +T ++ +TPL AA V ++L + + A+ +
Sbjct: 361 QYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 407
Score = 69.3 bits (162), Expect = 4e-11
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++T TPL A L++ + L+ GA ++ + T L IA+ +G + +V+ LLD G
Sbjct: 238 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 297
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
A+++ + T LH AA GH + LLDHGA + +NG++P+ AA+ V
Sbjct: 298 AQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVR 357
Query: 254 IL 255
+L
Sbjct: 358 LL 359
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + + + L++ G N + TPL A EG ++V L+ A+
Sbjct: 637 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANG 696
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L + A +G++ V L+ G VD G T LH A+ G+ +V LL
Sbjct: 697 NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLL 756
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H A + + G +PL AA++ +V +L
Sbjct: 757 QHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 788
Score = 33.5 bits (73), Expect = 2.4
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 26/127 (20%)
Query: 507 RSGQTLLHLAADRNTPVDDFHTSDVCQFPCA------RTSRLLLDCGADVDAADMNRRTP 560
R ++ L DR ++ ++ CA R S +LLD GA + A N +P
Sbjct: 284 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 343
Query: 561 LHVA-----------LISYQLTSDD------REQYNEAFCG---VVCELLSRGAHVDAMD 600
+H+A L+ Y DD + A CG V LL +GA ++
Sbjct: 344 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 403
Query: 601 LDGITPL 607
L+G TPL
Sbjct: 404 LNGFTPL 410
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 92.3 bits (219), Expect = 5e-18
Identities = 54/153 (35%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ GH ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 31 EEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 90
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 91 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 150
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 151 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 183
Score = 67.7 bits (158), Expect = 1e-10
Identities = 43/149 (28%), Positives = 70/149 (46%), Gaps = 1/149 (0%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL A+ GH + + L G++ N + TPL A + G + K L G +++
Sbjct: 2 ALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIK 61
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL G
Sbjct: 62 NREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQG 121
Query: 228 AKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + +G TPL A + +V L
Sbjct: 122 CFVDYQDRHGNTPLHVACKDGNMPIVVAL 150
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 67 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 115
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 116 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 175
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 176 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 212
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 64 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 123
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 124 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 183
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 184 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 217
Score = 45.6 bits (103), Expect = 6e-04
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTN 233
L +AA G+ DV Q L G+ + + T LH AA GH +V +L + G + + N
Sbjct: 3 LHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKN 62
Query: 234 ENGMTPLQCAAERARASVVEILA 256
G TPL A+ R +VE LA
Sbjct: 63 REGETPLLTASARGYHDIVECLA 85
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 91.9 bits (218), Expect = 7e-18
Identities = 72/215 (33%), Positives = 109/215 (50%), Gaps = 20/215 (9%)
Query: 51 LNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALW 110
++ID ++ T L A G E V+ LLE+ + +G T L
Sbjct: 1073 IDIDAQTESNHDTALTLACAGGHEELVQTLLER-----------GASIEHRDKKGFTPLI 1121
Query: 111 CASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ AGH+ +V+ L+ GAD+ + RT TPL AC GR ++V+ L+ GA+ N
Sbjct: 1122 LAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV 1181
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L +AA GY+++++ LL++GA ++ R + G + L AA GH A V LLD G
Sbjct: 1182 SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 1241
Query: 228 ----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
A++ TN N T L A + R VV +L R
Sbjct: 1242 SDINAQIETNRN--TALTLACFQGRTEVVSLLLDR 1274
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/189 (35%), Positives = 95/189 (50%), Gaps = 6/189 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G L
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFL 547
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM AA +G+L++V++LL +GA V G TAL +A
Sbjct: 548 EVADFLIKAGADIELG---CSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 604
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEA 269
E GH V LL GA + +E G TPL AA V+ L ++ V R A
Sbjct: 605 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANND 664
Query: 270 YELLGASFA 278
+ +L + A
Sbjct: 665 HTVLSLACA 673
Score = 86.2 bits (204), Expect = 3e-16
Identities = 62/156 (39%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+ GHL +VK L+ AGA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 565 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 624
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD-DRALCGATALHFAAECGHAAVVCSLL 224
++ T LM AA G++ VQFL+ GA V+ A T L A GH AVV LL
Sbjct: 625 HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 684
Query: 225 DHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
HGA ++G T L AA+ SVV L P
Sbjct: 685 AHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP 720
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/218 (33%), Positives = 106/218 (48%), Gaps = 17/218 (7%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+D+ +I+ S+ K TPL A GR+ V +LL + G K + +
Sbjct: 1136 LDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLAR----------GANK-EHRNVSDY 1184
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADI 164
T L A+ G++ I+K L+ AGA++N T + +PL A G VK L+ G+DI
Sbjct: 1185 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1244
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V L
Sbjct: 1245 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1304
Query: 224 LDHGAKM---LTNENGMTPLQCAAERARASVVEILAAR 258
LD GA + + T L AA++ E+L R
Sbjct: 1305 LDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGR 1342
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/138 (36%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G + IVK L
Sbjct: 261 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLL 320
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A GY+DVV+ LL+SGA ++D G T L A GH
Sbjct: 321 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 380
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LL++GA + T+ N
Sbjct: 381 EVARLLLENGAGINTHSN 398
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/129 (37%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G + V++L+ GA++
Sbjct: 597 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 656
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ N +T L +A G+L VV+ LL GA R G+T L AA+ GH +VVC L
Sbjct: 657 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 716
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 717 LDYPNNLLS 725
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/226 (30%), Positives = 103/226 (45%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+ + ++E T T L A G +V+
Sbjct: 1118 TPLILAATAGHVGVVEILLDN-GADIEAQSERTKD---------TPLSLACSGGRQEVVE 1167
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 1168 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 1227
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G+ V+ LLD G+ ++ + TAL A G VV LLD A + + G+T
Sbjct: 1228 NGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLT 1287
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 1288 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1333
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/196 (31%), Positives = 90/196 (45%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 1220 SPLMLAAMNGHTAAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRTEVVS 1269
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 1270 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1329
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L AA GH VV L+ GA + +N +TP
Sbjct: 1330 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP 1389
Query: 240 LQCAAERARASVVEIL 255
L A + VV L
Sbjct: 1390 LMAAFRKGHVKVVRYL 1405
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/183 (31%), Positives = 89/183 (48%), Gaps = 12/183 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A G R+LLE + T +F E +AL A GHL +V+
Sbjct: 369 TPLMEAGSAGHVEVARLLLEN---GAGINTHSN-EFKE------SALTLACYKGHLEMVR 418
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 419 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 478
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 479 HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETAL 538
Query: 241 QCA 243
A
Sbjct: 539 TLA 541
Score = 66.1 bits (154), Expect = 4e-10
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + K
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM AA G++ +V+ LL A V+ ++ G TAL +A G+ VV LL+ GA +
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 360
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL A V +L
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLL 386
Score = 58.8 bits (136), Expect = 6e-08
Identities = 43/129 (33%), Positives = 63/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 1287 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 1337
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G LD+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 1338 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 1397
Query: 183 YLDVVQFLL 191
++ VV++L+
Sbjct: 1398 HVKVVRYLV 1406
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
Query: 93 EGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRL 151
+G D V+ T+ + CA A+ + ++ A+ A ++ + L AC EG +
Sbjct: 191 DGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTAN---AGQSDNRSLAEACSEGDV 247
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-ATALHF 210
+ V+ L+ G +++ + + L +A GY ++ Q LL A V+DR + G T L
Sbjct: 248 NAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMA 307
Query: 211 AAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
AA GH +V LL H A + + G T L A VV++L
Sbjct: 308 AANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 353
Score = 56.8 bits (131), Expect = 2e-07
Identities = 27/56 (48%), Positives = 38/56 (67%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW A+ GHL +V+ LV+AGADV+ A TPL AA +G + +V+YLV+
Sbjct: 1352 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1407
Score = 39.9 bits (89), Expect = 0.028
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T +++ T L A GHLA+V+
Sbjct: 632 TPLMKAARAGHVCTVQFLISK-----GANVNRTTANNDH-----TVLSLACAGGHLAVVE 681
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G +V YL+
Sbjct: 682 LLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 717
Score = 36.7 bits (81), Expect = 0.26
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 469 VAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHT 528
V VA LLE+ ++ SA A + VR LL AD+ D+ HT
Sbjct: 380 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRF---LLEAGADQEHKTDEMHT 436
Query: 529 S--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVV 586
+ + C +RLLLD GA V+ + +PL +A + +
Sbjct: 437 ALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVE-------------LA 483
Query: 587 CELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
L+ RGA ++ ++ +G TPL+ + E +V
Sbjct: 484 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 516
Score = 36.3 bits (80), Expect = 0.35
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 1298 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIGRGA 1344
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +A+ GG
Sbjct: 1345 HIDVRNKKGNTPLWLAANGG 1364
Score = 31.5 bits (68), Expect = 9.9
Identities = 46/164 (28%), Positives = 60/164 (36%), Gaps = 27/164 (16%)
Query: 457 EYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQ 510
+ ++N TAL L GR LL+ N E G A G G+
Sbjct: 1247 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAA----SGGYAEVGR 1302
Query: 511 TLLHLAADRNTPV----DDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD N P D + + LL+ GA +D + TPL +A
Sbjct: 1303 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAA- 1361
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVAS 610
N VV L+ GA VDA D ITPL+A+
Sbjct: 1362 ------------NGGHLDVVQLLVQAGADVDAADNRKITPLMAA 1393
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 91.9 bits (218), Expect = 7e-18
Identities = 72/215 (33%), Positives = 109/215 (50%), Gaps = 20/215 (9%)
Query: 51 LNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALW 110
++ID ++ T L A G E V+ LLE+ + +G T L
Sbjct: 956 IDIDAQTESNHDTALTLACAGGHEELVQTLLER-----------GASIEHRDKKGFTPLI 1004
Query: 111 CASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ AGH+ +V+ L+ GAD+ + RT TPL AC GR ++V+ L+ GA+ N
Sbjct: 1005 LAATAGHVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV 1064
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L +AA GY+++++ LL++GA ++ R + G + L AA GH A V LLD G
Sbjct: 1065 SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 1124
Query: 228 ----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
A++ TN N T L A + R VV +L R
Sbjct: 1125 SDINAQIETNRN--TALTLACFQGRTEVVSLLLDR 1157
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/189 (35%), Positives = 95/189 (50%), Gaps = 6/189 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G L
Sbjct: 372 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFL 431
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM AA +G+L++V++LL +GA V G TAL +A
Sbjct: 432 EVADFLIKAGADIELG---CSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 488
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEA 269
E GH V LL GA + +E G TPL AA V+ L ++ V R A
Sbjct: 489 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANND 548
Query: 270 YELLGASFA 278
+ +L + A
Sbjct: 549 HTVLSLACA 557
Score = 86.2 bits (204), Expect = 3e-16
Identities = 62/156 (39%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+ GHL +VK L+ AGA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 449 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 508
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD-DRALCGATALHFAAECGHAAVVCSLL 224
++ T LM AA G++ VQFL+ GA V+ A T L A GH AVV LL
Sbjct: 509 HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 568
Query: 225 DHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
HGA ++G T L AA+ SVV L P
Sbjct: 569 AHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP 604
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/218 (33%), Positives = 106/218 (48%), Gaps = 17/218 (7%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+D+ +I+ S+ K TPL A GR+ V +LL + G K + +
Sbjct: 1019 LDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLAR----------GANK-EHRNVSDY 1067
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADI 164
T L A+ G++ I+K L+ AGA++N T + +PL A G VK L+ G+DI
Sbjct: 1068 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1127
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V L
Sbjct: 1128 NAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1187
Query: 224 LDHGAKM---LTNENGMTPLQCAAERARASVVEILAAR 258
LD GA + + T L AA++ E+L R
Sbjct: 1188 LDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGR 1225
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/129 (37%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G + V++L+ GA++
Sbjct: 481 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 540
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ N +T L +A G+L VV+ LL GA R G+T L AA+ GH +VVC L
Sbjct: 541 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 600
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 601 LDYPNNLLS 609
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/138 (36%), Positives = 74/138 (53%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + T L AA G + IVK L
Sbjct: 145 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITSLMAAANGGHVKIVKLL 204
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A GY+DVV+ LL+SGA ++D G T L A GH
Sbjct: 205 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 264
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LL++GA + T+ N
Sbjct: 265 EVARLLLENGAGINTHSN 282
Score = 77.8 bits (183), Expect = 1e-13
Identities = 58/216 (26%), Positives = 101/216 (46%), Gaps = 5/216 (2%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
D +DD++ + + + TP + A + P L + D
Sbjct: 905 DTLDDIMAVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQTES 964
Query: 105 GA-TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL A GH +V+ L++ GA + H + TPL A G + +V+ L+ +GAD
Sbjct: 965 NHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGAD 1024
Query: 164 IH-KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
I ++ + +T L +A G +VV+ LL GA + R + T L AA G+ ++
Sbjct: 1025 IEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKI 1084
Query: 223 LLDHGAKMLT---NENGMTPLQCAAERARASVVEIL 255
LL+ GA++ + ++ G++PL AA + V++L
Sbjct: 1085 LLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 1120
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/226 (30%), Positives = 102/226 (45%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+ +E + D T L A G +V+
Sbjct: 1001 TPLILAATAGHVGVVEILLDNGAD---IEAQSERTKD-------TPLSLACSGGRQEVVE 1050
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 1051 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 1110
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G+ V+ LLD G+ ++ + TAL A G VV LLD A + + G+T
Sbjct: 1111 NGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLT 1170
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 1171 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1216
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/196 (31%), Positives = 90/196 (45%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 1103 SPLMLAAMNGHTAAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRTEVVS 1152
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 1153 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1212
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L AA GH VV L+ GA + +N +TP
Sbjct: 1213 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP 1272
Query: 240 LQCAAERARASVVEIL 255
L A + VV L
Sbjct: 1273 LMAAFRKGHVKVVRYL 1288
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/183 (31%), Positives = 89/183 (48%), Gaps = 12/183 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A G R+LLE + T +F E +AL A GHL +V+
Sbjct: 253 TPLMEAGSAGHVEVARLLLEN---GAGINTHSN-EFKE------SALTLACYKGHLEMVR 302
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 303 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 362
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 363 HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETAL 422
Query: 241 QCA 243
A
Sbjct: 423 TLA 425
Score = 66.9 bits (156), Expect = 2e-10
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + K
Sbjct: 125 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 184
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM AA G++ +V+ LL A V+ ++ G TAL +A G+ VV LL+ GA +
Sbjct: 185 DITSLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 244
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL A V +L
Sbjct: 245 EDHNENGHTPLMEAGSAGHVEVARLL 270
Score = 58.8 bits (136), Expect = 6e-08
Identities = 43/129 (33%), Positives = 63/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 1170 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 1220
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G LD+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 1221 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 1280
Query: 183 YLDVVQFLL 191
++ VV++L+
Sbjct: 1281 HVKVVRYLV 1289
Score = 58.0 bits (134), Expect = 1e-07
Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 6/166 (3%)
Query: 93 EGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRL 151
+G D V+ T+ + CA A+ + ++ A+ A ++ + L AC EG +
Sbjct: 75 DGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTAN---AGQSDNRSLAEACSEGDV 131
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-ATALHF 210
+ V+ L+ G +++ + + L +A GY ++ Q LL A V+DR + G T+L
Sbjct: 132 NAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITSLMA 191
Query: 211 AAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
AA GH +V LL H A + + G T L A VV++L
Sbjct: 192 AANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 237
Score = 56.8 bits (131), Expect = 2e-07
Identities = 27/56 (48%), Positives = 38/56 (67%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW A+ GHL +V+ LV+AGADV+ A TPL AA +G + +V+YLV+
Sbjct: 1235 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 1290
Score = 39.9 bits (89), Expect = 0.028
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T +++ T L A GHLA+V+
Sbjct: 516 TPLMKAARAGHVCTVQFLISK-----GANVNRTTANNDH-----TVLSLACAGGHLAVVE 565
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G +V YL+
Sbjct: 566 LLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 601
Score = 36.7 bits (81), Expect = 0.26
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 469 VAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHT 528
V VA LLE+ ++ SA A + VR LL AD+ D+ HT
Sbjct: 264 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRF---LLEAGADQEHKTDEMHT 320
Query: 529 S--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVV 586
+ + C +RLLLD GA V+ + +PL +A + +
Sbjct: 321 ALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVE-------------LA 367
Query: 587 CELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
L+ RGA ++ ++ +G TPL+ + E +V
Sbjct: 368 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 400
Score = 36.3 bits (80), Expect = 0.35
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 1181 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIGRGA 1227
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +A+ GG
Sbjct: 1228 HIDVRNKKGNTPLWLAANGG 1247
Score = 31.5 bits (68), Expect = 9.9
Identities = 46/164 (28%), Positives = 60/164 (36%), Gaps = 27/164 (16%)
Query: 457 EYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQ 510
+ ++N TAL L GR LL+ N E G A G G+
Sbjct: 1130 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAA----SGGYAEVGR 1185
Query: 511 TLLHLAADRNTPV----DDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD N P D + + LL+ GA +D + TPL +A
Sbjct: 1186 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAA- 1244
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVAS 610
N VV L+ GA VDA D ITPL+A+
Sbjct: 1245 ------------NGGHLDVVQLLVQAGADVDAADNRKITPLMAA 1276
>AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22206 fis, clone HRC01431. ).
Length = 460
Score = 91.5 bits (217), Expect = 9e-18
Identities = 72/215 (33%), Positives = 109/215 (50%), Gaps = 20/215 (9%)
Query: 51 LNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALW 110
++ID ++ T L A G E V+ LLE+ + +G T L
Sbjct: 37 IDIDAQTESNHDTALTLACAGGHEELVQTLLER-----------GASIEHRDKKGFTPLI 85
Query: 111 CASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ AGH+ +V+ L+ GAD+ + RT TPL AC GR ++V+ L+ GA+ N
Sbjct: 86 LAATAGHVGVVEILLGNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV 145
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L +AA GY+++++ LL++GA ++ R + G + L AA GH A V LLD G
Sbjct: 146 SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMG 205
Query: 228 ----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
A++ TN N T L A + R VV +L R
Sbjct: 206 SDINAQIETNRN--TALTLACFQGRTEVVSLLLDR 238
Score = 84.2 bits (199), Expect = 1e-15
Identities = 71/213 (33%), Positives = 103/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 105 DIEAQSERTKDTPLSLACSGGRQEVVELLLAR----------GANK-EHRNVSDYTPLSL 153
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G VK L+ G+DI+ +
Sbjct: 154 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIE 213
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 214 TNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 273
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 274 DVNAPPVPSSRDTALTIAADKGHYKFCELLIGR 306
Score = 75.8 bits (178), Expect = 5e-13
Identities = 70/226 (30%), Positives = 102/226 (45%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL + ++E T T L A G +V+
Sbjct: 82 TPLILAATAGHVGVVEILLGN-GADIEAQSERTKD---------TPLSLACSGGRQEVVE 131
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 132 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 191
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G+ V+ LLD G+ ++ + TAL A G VV LLD A + + G+T
Sbjct: 192 NGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLT 251
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 252 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 297
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/196 (31%), Positives = 90/196 (45%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 184 SPLMLAAMNGHTAAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRTEVVS 233
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 234 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 293
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L AA GH VV L+ GA + +N +TP
Sbjct: 294 KGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITP 353
Query: 240 LQCAAERARASVVEIL 255
L A + VV L
Sbjct: 354 LMAAFRKGHVKVVRYL 369
Score = 58.8 bits (136), Expect = 6e-08
Identities = 43/129 (33%), Positives = 63/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 251 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 301
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G LD+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 302 LLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 361
Query: 183 YLDVVQFLL 191
++ VV++L+
Sbjct: 362 HVKVVRYLV 370
Score = 56.8 bits (131), Expect = 2e-07
Identities = 27/56 (48%), Positives = 38/56 (67%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW A+ GHL +V+ LV+AGADV+ A TPL AA +G + +V+YLV+
Sbjct: 316 KGNTPLWLAANGGHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK 371
Score = 36.3 bits (80), Expect = 0.35
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 262 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIGRGA 308
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +A+ GG
Sbjct: 309 HIDVRNKKGNTPLWLAANGG 328
Score = 31.5 bits (68), Expect = 9.9
Identities = 46/164 (28%), Positives = 60/164 (36%), Gaps = 27/164 (16%)
Query: 457 EYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQ 510
+ ++N TAL L GR LL+ N E G A G G+
Sbjct: 211 QIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAA----SGGYAEVGR 266
Query: 511 TLLHLAADRNTPV----DDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD N P D + + LL+ GA +D + TPL +A
Sbjct: 267 VLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAA- 325
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVAS 610
N VV L+ GA VDA D ITPL+A+
Sbjct: 326 ------------NGGHLDVVQLLVQAGADVDAADNRKITPLMAA 357
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/189 (35%), Positives = 95/189 (50%), Gaps = 6/189 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G L
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFL 547
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM AA +G+L++V++LL +GA V G TAL +A
Sbjct: 548 EVADFLIKAGADIELG---CSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 604
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEA 269
E GH V LL GA + +E G TPL AA V+ L ++ V R A
Sbjct: 605 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANND 664
Query: 270 YELLGASFA 278
+ +L + A
Sbjct: 665 HTVLSLACA 673
Score = 86.2 bits (204), Expect = 3e-16
Identities = 62/156 (39%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+ GHL +VK L+ AGA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 565 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 624
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD-DRALCGATALHFAAECGHAAVVCSLL 224
++ T LM AA G++ VQFL+ GA V+ A T L A GH AVV LL
Sbjct: 625 HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 684
Query: 225 DHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
HGA ++G T L AA+ SVV L P
Sbjct: 685 AHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP 720
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/138 (36%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G + IVK L
Sbjct: 261 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLL 320
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A GY+DVV+ LL+SGA ++D G T L A GH
Sbjct: 321 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 380
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LL++GA + T+ N
Sbjct: 381 EVARLLLENGAGINTHSN 398
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/129 (37%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G + V++L+ GA++
Sbjct: 597 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 656
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ N +T L +A G+L VV+ LL GA R G+T L AA+ GH +VVC L
Sbjct: 657 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 716
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 717 LDYPNNLLS 725
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/183 (31%), Positives = 89/183 (48%), Gaps = 12/183 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A G R+LLE + T +F E +AL A GHL +V+
Sbjct: 369 TPLMEAGSAGHVEVARLLLEN---GAGINTHSN-EFKE------SALTLACYKGHLEMVR 418
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 419 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 478
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 479 HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETAL 538
Query: 241 QCA 243
A
Sbjct: 539 TLA 541
Score = 66.1 bits (154), Expect = 4e-10
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + K
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM AA G++ +V+ LL A V+ ++ G TAL +A G+ VV LL+ GA +
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 360
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL A V +L
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLL 386
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
Query: 93 EGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRL 151
+G D V+ T+ + CA A+ + ++ A+ A ++ + L AC EG +
Sbjct: 191 DGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTAN---AGQSDNRSLAEACSEGDV 247
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-ATALHF 210
+ V+ L+ G +++ + + L +A GY ++ Q LL A V+DR + G T L
Sbjct: 248 NAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMA 307
Query: 211 AAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
AA GH +V LL H A + + G T L A VV++L
Sbjct: 308 AANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 353
Score = 39.9 bits (89), Expect = 0.028
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T +++ T L A GHLA+V+
Sbjct: 632 TPLMKAARAGHVCTVQFLISK-----GANVNRTTANNDH-----TVLSLACAGGHLAVVE 681
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G +V YL+
Sbjct: 682 LLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 717
Score = 36.7 bits (81), Expect = 0.26
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 469 VAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHT 528
V VA LLE+ ++ SA A + VR LL AD+ D+ HT
Sbjct: 380 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRF---LLEAGADQEHKTDEMHT 436
Query: 529 S--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVV 586
+ + C +RLLLD GA V+ + +PL +A + +
Sbjct: 437 ALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVE-------------LA 483
Query: 587 CELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
L+ RGA ++ ++ +G TPL+ + E +V
Sbjct: 484 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 516
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/189 (35%), Positives = 95/189 (50%), Gaps = 6/189 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G L
Sbjct: 308 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFL 367
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM AA +G+L++V++LL +GA V G TAL +A
Sbjct: 368 EVADFLIKAGADIELG---CSTPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 424
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEA 269
E GH V LL GA + +E G TPL AA V+ L ++ V R A
Sbjct: 425 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANND 484
Query: 270 YELLGASFA 278
+ +L + A
Sbjct: 485 HTVLSLACA 493
Score = 86.2 bits (204), Expect = 3e-16
Identities = 62/156 (39%), Positives = 81/156 (51%), Gaps = 2/156 (1%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+ GHL +VK L+ AGA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 385 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 444
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD-DRALCGATALHFAAECGHAAVVCSLL 224
++ T LM AA G++ VQFL+ GA V+ A T L A GH AVV LL
Sbjct: 445 HESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLL 504
Query: 225 DHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
HGA ++G T L AA+ SVV L P
Sbjct: 505 AHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYP 540
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/138 (36%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G + IVK L
Sbjct: 81 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLL 140
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A GY+DVV+ LL+SGA ++D G T L A GH
Sbjct: 141 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 200
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LL++GA + T+ N
Sbjct: 201 EVARLLLENGAGINTHSN 218
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/129 (37%), Positives = 72/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G + V++L+ GA++
Sbjct: 417 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANV 476
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ N +T L +A G+L VV+ LL GA R G+T L AA+ GH +VVC L
Sbjct: 477 NRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYL 536
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 537 LDYPNNLLS 545
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/183 (31%), Positives = 89/183 (48%), Gaps = 12/183 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A G R+LLE + T +F E +AL A GHL +V+
Sbjct: 189 TPLMEAGSAGHVEVARLLLEN---GAGINTHSN-EFKE------SALTLACYKGHLEMVR 238
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 239 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 298
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 299 HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETAL 358
Query: 241 QCA 243
A
Sbjct: 359 TLA 361
Score = 66.1 bits (154), Expect = 4e-10
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + K
Sbjct: 61 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 120
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM AA G++ +V+ LL A V+ ++ G TAL +A G+ VV LL+ GA +
Sbjct: 121 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 180
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL A V +L
Sbjct: 181 EDHNENGHTPLMEAGSAGHVEVARLL 206
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
Query: 93 EGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRL 151
+G D V+ T+ + CA A+ + ++ A+ A ++ + L AC EG +
Sbjct: 11 DGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTAN---AGQSDNRSLAEACSEGDV 67
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-ATALHF 210
+ V+ L+ G +++ + + L +A GY ++ Q LL A V+DR + G T L
Sbjct: 68 NAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMA 127
Query: 211 AAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
AA GH +V LL H A + + G T L A VV++L
Sbjct: 128 AANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 173
Score = 39.9 bits (89), Expect = 0.028
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T +++ T L A GHLA+V+
Sbjct: 452 TPLMKAARAGHVCTVQFLISK-----GANVNRTTANNDH-----TVLSLACAGGHLAVVE 501
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G +V YL+
Sbjct: 502 LLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLL 537
Score = 36.7 bits (81), Expect = 0.26
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 469 VAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHT 528
V VA LLE+ ++ SA A + VR LL AD+ D+ HT
Sbjct: 200 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRF---LLEAGADQEHKTDEMHT 256
Query: 529 S--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVV 586
+ + C +RLLLD GA V+ + +PL +A + +
Sbjct: 257 ALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVE-------------LA 303
Query: 587 CELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
L+ RGA ++ ++ +G TPL+ + E +V
Sbjct: 304 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 336
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined
breast cancer antigen NY-BR-16 protein.
Length = 1188
Score = 90.6 bits (215), Expect = 2e-17
Identities = 71/197 (36%), Positives = 97/197 (49%), Gaps = 15/197 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G L +
Sbjct: 502 TPLMEAAREGHEEMVALLLGQ-GANINAQTEETQE---------TALTLACCGGFLEVAD 551
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 552 FLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENG 608
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQ 241
+ DV LL +GA ++ + G T L AA GH V L+ GA+ + + MT L
Sbjct: 609 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILS 668
Query: 242 C-AAERARASVVEILAA 257
A +VVE+L A
Sbjct: 669 ALACAGGHLAVVELLLA 685
Score = 89.8 bits (213), Expect = 3e-17
Identities = 62/168 (36%), Positives = 87/168 (51%), Gaps = 5/168 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G L
Sbjct: 488 ERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFL 547
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM AA +G+L++V++LL +GA V G TAL +A
Sbjct: 548 EVADFLIKAGADIELGC---STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYA 604
Query: 212 AECGHAAVVCSLLDHGAKML-TNENGMTPLQCAAERARASVVEILAAR 258
E GH V LL GA + +E G TPL AA V+ L ++
Sbjct: 605 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISK 652
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/138 (36%), Positives = 75/138 (54%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G + IVK L
Sbjct: 261 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLL 320
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A GY+DVV+ LL+SGA ++D G T L A GH
Sbjct: 321 LAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHV 380
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LL++GA + T+ N
Sbjct: 381 EVARLLLENGAGINTHSN 398
Score = 79.4 bits (187), Expect = 4e-14
Identities = 50/124 (40%), Positives = 66/124 (53%), Gaps = 1/124 (0%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+ GHL +VK L+ AGA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 565 STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 624
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALH-FAAECGHAAVVCSLL 224
++ T LM AA G++ VQFL+ GA + T L A GH AVV LL
Sbjct: 625 HESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILSALACAGGHLAVVELLL 684
Query: 225 DHGA 228
HGA
Sbjct: 685 AHGA 688
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/183 (31%), Positives = 89/183 (48%), Gaps = 12/183 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A G R+LLE + T +F E +AL A GHL +V+
Sbjct: 369 TPLMEAGSAGHVEVARLLLEN---GAGINTHSN-EFKE------SALTLACYKGHLEMVR 418
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 419 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 478
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 479 HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETAL 538
Query: 241 QCA 243
A
Sbjct: 539 TLA 541
Score = 69.3 bits (162), Expect = 4e-11
Identities = 46/129 (35%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G + V++L+ GA+
Sbjct: 597 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAEC 656
Query: 165 HKANKYNNTCLM-IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T L +A G+L VV+ LL GA R G+T L A + GH +V C L
Sbjct: 657 ESEPQLIMTILSALACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAPKGGHTSVGCYL 716
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 717 LDYPNNLLS 725
Score = 66.1 bits (154), Expect = 4e-10
Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + K
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM AA G++ +V+ LL A V+ ++ G TAL +A G+ VV LL+ GA +
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASI 360
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL A V +L
Sbjct: 361 EDHNENGHTPLMEAGSAGHVEVARLL 386
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
Query: 93 EGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRL 151
+G D V+ T+ + CA A+ + ++ A+ A ++ + L AC EG +
Sbjct: 191 DGKAFADPEVLRRLTSSVSCALDEAAAALTRMRAESTAN---AGQSDNRSLAEACSEGDV 247
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-ATALHF 210
+ V+ L+ G +++ + + L +A GY ++ Q LL A V+DR + G T L
Sbjct: 248 NAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMA 307
Query: 211 AAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
AA GH +V LL H A + + G T L A VV++L
Sbjct: 308 AANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVL 353
Score = 36.7 bits (81), Expect = 0.26
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 18/153 (11%)
Query: 469 VAVAGRLLEDSGNCERWLSQGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHT 528
V VA LLE+ ++ SA A + VR LL AD+ D+ HT
Sbjct: 380 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRF---LLEAGADQEHKTDEMHT 436
Query: 529 S--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVV 586
+ + C +RLLLD GA V+ + +PL +A + +
Sbjct: 437 ALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVE-------------LA 483
Query: 587 CELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
L+ RGA ++ ++ +G TPL+ + E +V
Sbjct: 484 ALLIERGASLEEVNDEGYTPLMEAAREGHEEMV 516
>BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein.
Length = 1672
Score = 90.2 bits (214), Expect = 2e-17
Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++ TAL AS GH+ IV+ L+K G ++ H T L AC++GR D+V+ L+ HGA
Sbjct: 27 LDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGA 86
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ Y+ ++ AA +G+ D+V LL +GA+V+ G T L +AA GH V
Sbjct: 87 NPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKH 146
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERA-RASVVEILAARPEV 261
LL GA + N MT L A + SV EIL P V
Sbjct: 147 LLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 187
Score = 85.0 bits (201), Expect = 8e-16
Identities = 71/226 (31%), Positives = 110/226 (48%), Gaps = 16/226 (7%)
Query: 40 YEKKTDEIDDLLN--IDVCSDGVKCT-PLITAARHGREGAVRILLEKFRPPVCLETEGTV 96
Y+ +TD ++ LL+ + G+ P+I AA G V +LL+ C
Sbjct: 71 YKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCS------ 124
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
D+Y G T L A+ GHL VK L+ GADV+ T L A G VK
Sbjct: 125 --DKY---GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKE 179
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
+++ +++ +K NT LMIA+ +G+ ++VQ LLD+G V+ G T L A GH
Sbjct: 180 ILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGH 239
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVV-EILAARPE 260
+V +LL A + + ++ T L A E+ A++V +IL P+
Sbjct: 240 VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPD 285
Score = 80.6 bits (190), Expect = 2e-14
Identities = 55/147 (37%), Positives = 78/147 (53%), Gaps = 1/147 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G+L IVK L+K GA+ N T L +A EG + IV+ L++ G ++ +
Sbjct: 3 AAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGG 62
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T LM A YKG DVV+ LL GA L + +AA GHA +V LL +GAK+
Sbjct: 63 WTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVN 122
Query: 231 LTNENGMTPLQCAAERARASVVEILAA 257
+++ G TPL AA + V+ L A
Sbjct: 123 CSDKYGTTPLVWAARKGHLECVKHLLA 149
Score = 72.5 bits (170), Expect = 4e-12
Identities = 67/212 (31%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 51 LNIDVCSDGVKC-TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
+ DV +G T LI A + G +V+ +L++ P V L + +G TAL
Sbjct: 150 MGADVDQEGANSMTALIVAVKGGYTQSVKEILKR-NPNVNLTDK----------DGNTAL 198
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
AS GH IV+ L+ AG VN R+ T L A G ++IV+ L++ ADI +
Sbjct: 199 MIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQ 258
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK 229
N T L A KG +V+ +L + G T L A + + VV LLD GAK
Sbjct: 259 DNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAK 318
Query: 230 M-LTNENGMTPLQCAAERARASVVEILAARPE 260
+ ++ G TPL A + E+L P+
Sbjct: 319 VSAVDKKGDTPLHIAIRGRSRKLAELLLRNPK 350
Score = 46.8 bits (106), Expect = 2e-04
Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE- 234
MIAA +G L++V+ L+ +GA + L TAL A++ GH +V LL G + +
Sbjct: 1 MIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDM 60
Query: 235 NGMTPLQCAAERARASVVEIL---AARPEVT 262
G T L A + R VVE+L A P VT
Sbjct: 61 GGWTALMWACYKGRTDVVELLLSHGANPSVT 91
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 576 CENGHTDVADVLLQAGADLDKQEDMKTILE 605
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 580 HTDVADVLLQAGADLD 595
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein.
Length = 581
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 55.2 bits (127), Expect = 7e-07
Identities = 37/103 (35%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
++ +L++ GADI +T LM A+ +G+L++V++LL SG
Sbjct: 519 EVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASG 558
Score = 54.4 bits (125), Expect = 1e-06
Identities = 37/120 (30%), Positives = 62/120 (51%), Gaps = 4/120 (3%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KA 167
L A+ GH+ + L++ GA++ TPL A EG ++V L+ GA+I+ +
Sbjct: 442 LTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L +A G+ +V FL+ +GA ++ L +T L A++ GH +V LL G
Sbjct: 502 EETQETALTLACCGGFSEVADFLIKAGADIE---LGCSTPLMEASQEGHLELVKYLLASG 558
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 48.0 bits (109), Expect = 1e-04
Identities = 38/99 (38%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG 161
L+KAGAD+ STPL A EG L++VKYL+ G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASG 558
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 576 CENGHTDVADVLLQAGADLDKQEDMKTILE 605
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 580 HTDVADVLLQAGADLD 595
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 576 CENGHTDVADVLLQAGADLDKQEDMKTILE 605
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 580 HTDVADVLLQAGADLD 595
Score = 72.5 bits (170), Expect = 4e-12
Identities = 50/146 (34%), Positives = 74/146 (50%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 46.8 bits (106), Expect = 2e-04
Identities = 38/135 (28%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 616
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 221 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 280
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 281 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 340
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 341 EVARVLLDHGAGINTHSN 358
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 448 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 507
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 508 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 564
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 565 CENGHTDVADVLLQAGADLDKQEDMKTILE 594
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 201 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 260
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 261 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 320
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 321 EDHNENGHTPLMEAASAGHVEVARVL 346
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 329 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 378
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 379 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 438
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 439 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 498
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 499 TLACCGGFSEVADFL 513
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 462 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 511
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 512 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 568
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 569 HTDVADVLLQAGADLD 584
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 179 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 238
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 239 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 298
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 299 TYACAGGFVDIVKVL 313
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 320 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 379
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 380 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 436
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 437 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 476
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 576 CENGHTDVADVLLQAGADLDKQEDMKTILE 605
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 580 HTDVADVLLQAGADLD 595
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 90.2 bits (214), Expect = 2e-17
Identities = 54/141 (38%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G +AL A +GHL V L+ GA +N + PL A F G L+++K LV GAD+
Sbjct: 158 GRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADL 217
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ L AA G ++VV++LL GA +D+ G TALH A G AV L+
Sbjct: 218 GCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELV 277
Query: 225 DHGAKM-LTNENGMTPLQCAA 244
+ GA + N+ G TPL AA
Sbjct: 278 NAGANVNQPNDKGFTPLHVAA 298
Score = 74.9 bits (176), Expect = 8e-13
Identities = 46/124 (37%), Positives = 65/124 (52%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ GHL ++K LV GAD+ R L A G++++VKYL+R GA+I + N +
Sbjct: 198 AAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFG 257
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
NT L IA Y G V L+++GA V+ G T LH AA + A+ LL +
Sbjct: 258 NTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGAFY 317
Query: 232 TNEN 235
N N
Sbjct: 318 FNYN 321
Score = 52.0 bits (119), Expect = 7e-06
Identities = 42/137 (30%), Positives = 67/137 (48%), Gaps = 2/137 (1%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQ 188
+ +N A R+ + L A G L+ V L+ GA ++ +K L AA+ G+L+V++
Sbjct: 149 SSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLK 208
Query: 189 FLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERA 247
L+ GA + + G LH AA G VV LL GA++ N G T L A
Sbjct: 209 LLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLG 268
Query: 248 RASV-VEILAARPEVTR 263
+ +V +E++ A V +
Sbjct: 269 QDAVAIELVNAGANVNQ 285
Score = 48.8 bits (111), Expect = 6e-05
Identities = 53/209 (25%), Positives = 89/209 (42%), Gaps = 13/209 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATA-----LWCA 112
D + TPL AA G +++LL + + ++K Y+ GA LW A
Sbjct: 37 DQERRTPLHAAAYVGDVPILQLLL--ITGFLHTSSPPSIKIGNYIPTGANVNAKDTLWLA 94
Query: 113 -----SGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
+ + + ++ L+ ADVN + TPL A + L + ++ A
Sbjct: 95 PLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVA 154
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
++ + L A + G+L+ V LL+ GA ++ LH+AA GH V+ L+ G
Sbjct: 155 DRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG 214
Query: 228 AKM-LTNENGMTPLQCAAERARASVVEIL 255
A + + G L AA + VV+ L
Sbjct: 215 ADLGCKDRKGYGLLHTAAASGQIEVVKYL 243
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 3/94 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G L A+ +G + +VK L++ GA+++ +T L AC+ G+ + LV GA+
Sbjct: 223 KGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGAN 282
Query: 164 IHKANKYNNTCLMIAAY--KGYLDVVQFLLDSGA 195
+++ N T L +AA G L ++ L+++GA
Sbjct: 283 VNQPNDKGFTPLHVAAVSTNGAL-CLELLVNNGA 315
Score = 31.5 bits (68), Expect = 9.9
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF--EGRLDIV 154
+ DE G TAL A G A+ LV AGA+VN TPL A G L +
Sbjct: 249 EIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGAL-CL 307
Query: 155 KYLVRHGA 162
+ LV +GA
Sbjct: 308 ELLVNNGA 315
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 246 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 305
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 306 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 365
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 366 EVARVLLDHGAGINTHSN 383
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 1120 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1179
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 1180 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1239
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 1240 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 1279
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 1146 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 1194
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 1195 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 1254
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 1255 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 1314
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 1315 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 1347
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 1123 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 1172
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 1173 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 1232
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 1233 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 1292
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 1293 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1338
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 473 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 532
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 533 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 589
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 590 CENGHTDVADVLLQAGADLDKQEDMKTILE 619
Score = 77.0 bits (181), Expect = 2e-13
Identities = 71/216 (32%), Positives = 96/216 (44%), Gaps = 34/216 (15%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 487 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 536
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 537 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 593
Query: 183 YLDVVQFLLDSGARVDDR-------------------ALCGATALHFAAECGHAAVVCSL 223
+ DV LL +GA +D + + G T L AA GH V L
Sbjct: 594 HTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFL 653
Query: 224 LDHGAKM--LTNENGMTPLQCAAERARASVVEILAA 257
+ GA + T N T + A +VVE+L A
Sbjct: 654 ISKGANVNRATANNDHTVVSLACAGGHLAVVELLLA 689
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 226 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 285
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 286 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 345
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 346 EDHNENGHTPLMEAASAGHVEVARVL 371
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 354 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 403
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 404 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 463
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 464 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 523
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 524 TLACCGGFSEVADFL 538
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 1225 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 1274
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 1275 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1334
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 1335 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1394
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 1395 LMSAFRKGHVKVVQYL 1410
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 1090 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1149
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 1150 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 1209
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 1210 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 1242
Score = 64.5 bits (150), Expect = 1e-09
Identities = 43/105 (40%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Query: 90 LETEGTVKFDEYVIEGA-TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACF 147
LE K E+ EG T L A+ AGHL V+ L+ GA+VN AT T + AC
Sbjct: 618 LEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACA 677
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
G L +V+ L+ HGAD K +T L+ AA G+ +VV +LLD
Sbjct: 678 GGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 722
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/148 (33%), Positives = 72/148 (48%), Gaps = 20/148 (13%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVN-------------------HATRTVSTPLRAA 145
G TAL A GH + L++AGAD++ H + TPL A
Sbjct: 582 GDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKA 641
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
G L V++L+ GA++++A N+ T + +A G+L VV+ LL GA R G
Sbjct: 642 ARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDG 701
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLT 232
+T L AA+ GH VV LLD+ +L+
Sbjct: 702 STMLIEAAKGGHTNVVSYLLDYPNNVLS 729
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 1292 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 1342
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 1343 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1402
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 1403 HVKVVQYLV 1411
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 1357 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1412
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 204 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 263
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 264 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 323
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 324 TYACAGGFVDIVKVL 338
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 1081 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 1139
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 1140 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 1177
Score = 42.3 bits (95), Expect = 0.005
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T D V+ +L CA GHLA+V+
Sbjct: 636 TPLMKAARAGHLCTVQFLISK----GANVNRATANNDHTVV----SLACA--GGHLAVVE 685
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G ++V YL+
Sbjct: 686 LLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 721
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 1303 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 1349
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 1350 HIDVRNKKGNTPLWLASNGG 1369
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 345 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 404
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 405 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 461
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 462 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 501
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 40 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 99
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 100 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 159
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 160 EVARVLLDHGAGINTHSN 177
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 267 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 326
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 327 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 383
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 384 CENGHTDVADVLLQAGADLDKQEDMKTILE 413
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 20 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 79
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 80 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 139
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 140 EDHNENGHTPLMEAASAGHVEVARVL 165
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 148 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 197
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 198 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 257
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 258 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 317
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 318 TLACCGGFSEVADFL 332
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 281 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 330
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 331 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 387
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 388 HTDVADVLLQAGADLD 403
Score = 49.2 bits (112), Expect = 5e-05
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 129 ADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A GY ++
Sbjct: 3 AENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELA 62
Query: 188 QFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQCAAE 245
Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L A
Sbjct: 63 QVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACA 122
Query: 246 RARASVVEIL 255
+V++L
Sbjct: 123 GGFVDIVKVL 132
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 139 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 198
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 199 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 255
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 256 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 295
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 89.0 bits (211), Expect = 5e-17
Identities = 65/177 (36%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEA 266
E GH V LL GA + +E G TPL AA V+ L ++ V RA A
Sbjct: 576 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATA 632
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 1087 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1146
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 1147 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1206
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 1207 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 1246
Score = 86.6 bits (205), Expect = 2e-16
Identities = 62/157 (39%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L AS GHL +VK L+ +GA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 536 STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 595
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCSL 223
++ T LM AA G+L VQFL+ GA V +RA T + A GH AVV L
Sbjct: 596 HESEGGRTPLMKAARAGHLCTVQFLISKGANV-NRATANNDHTVVSLACAGGHLAVVELL 654
Query: 224 LDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
L HGA ++G T L AA+ +VV L P
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYP 691
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 1113 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 1161
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 1162 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 1221
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 1222 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 1281
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 1282 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 1314
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 1090 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 1139
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 1140 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 1199
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 1200 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 1259
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 1260 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1305
Score = 77.4 bits (182), Expect = 2e-13
Identities = 49/129 (37%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G L V++L+ GA++
Sbjct: 568 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANV 627
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++A N +T + +A G+L VV+ LL GA R G+T L AA+ GH VV L
Sbjct: 628 NRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYL 687
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 688 LDYPNNVLS 696
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 1192 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 1241
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 1242 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1301
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 1302 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1361
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 1362 LMSAFRKGHVKVVQYL 1377
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 1057 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1116
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 1117 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 1176
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 1177 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 1209
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 1259 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 1309
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 1310 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1369
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 1370 HVKVVQYLV 1378
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 1324 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 1048 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 1106
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 1107 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 1144
Score = 42.3 bits (95), Expect = 0.005
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T D V+ +L CA GHLA+V+
Sbjct: 603 TPLMKAARAGHLCTVQFLISK----GANVNRATANNDHTVV----SLACA--GGHLAVVE 652
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G ++V YL+
Sbjct: 653 LLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 1270 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 1316
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 1317 HIDVRNKKGNTPLWLASNGG 1336
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 89.0 bits (211), Expect = 5e-17
Identities = 65/177 (36%), Positives = 90/177 (50%), Gaps = 6/177 (3%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEA 266
E GH V LL GA + +E G TPL AA V+ L ++ V RA A
Sbjct: 576 CENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATA 632
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 1087 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 1146
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 1147 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 1206
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 1207 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 1246
Score = 86.6 bits (205), Expect = 2e-16
Identities = 62/157 (39%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L AS GHL +VK L+ +GA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 536 STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLE 595
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCSL 223
++ T LM AA G+L VQFL+ GA V +RA T + A GH AVV L
Sbjct: 596 HESEGGRTPLMKAARAGHLCTVQFLISKGANV-NRATANNDHTVVSLACAGGHLAVVELL 654
Query: 224 LDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
L HGA ++G T L AA+ +VV L P
Sbjct: 655 LAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYP 691
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 1113 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 1161
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 1162 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 1221
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 1222 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 1281
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 1282 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 1314
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 1090 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 1139
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 1140 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 1199
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 1200 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 1259
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 1260 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 1305
Score = 77.4 bits (182), Expect = 2e-13
Identities = 49/129 (37%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A GH + L++AGAD+ H + TPL A G L V++L+ GA++
Sbjct: 568 GDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANV 627
Query: 165 HKANKYN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++A N +T + +A G+L VV+ LL GA R G+T L AA+ GH VV L
Sbjct: 628 NRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYL 687
Query: 224 LDHGAKMLT 232
LD+ +L+
Sbjct: 688 LDYPNNVLS 696
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 1192 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 1241
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 1242 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 1301
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 1302 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 1361
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 1362 LMSAFRKGHVKVVQYL 1377
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 1057 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1116
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 1117 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 1176
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 1177 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 1209
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 1259 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 1309
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 1310 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 1369
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 1370 HVKVVQYLV 1378
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 1324 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 1048 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 1106
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 1107 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 1144
Score = 42.3 bits (95), Expect = 0.005
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T D V+ +L CA GHLA+V+
Sbjct: 603 TPLMKAARAGHLCTVQFLISK----GANVNRATANNDHTVV----SLACA--GGHLAVVE 652
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G ++V YL+
Sbjct: 653 LLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 688
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 1270 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 1316
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 1317 HIDVRNKKGNTPLWLASNGG 1336
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 90.2 bits (214), Expect = 2e-17
Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 1/138 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADV-NHATRTVSTPLRAACFEGRLDIVKYL 157
+E+ EG + L A AG+ + + L+ A+V + + TPL AA G LDIVK L
Sbjct: 232 NEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLL 291
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+ H AD++ + NT L A G++D+V+ LL+ GA ++D G T L AA GH
Sbjct: 292 LLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHV 351
Query: 218 AVVCSLLDHGAKMLTNEN 235
V LLDHGA + T+ N
Sbjct: 352 EVARVLLDHGAGINTHSN 369
Score = 79.0 bits (186), Expect = 5e-14
Identities = 55/150 (36%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRL 151
E +E EG T L A+ GH +V L+ GA++N T T T L AC G
Sbjct: 459 ERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFS 518
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
++ +L++ GADI +T LM A+ +G+L++V++LL SGA V G TAL +A
Sbjct: 519 EVADFLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYA 575
Query: 212 AECGHAAVVCSLLDHGAKMLTNENGMTPLQ 241
E GH V LL GA + E+ T L+
Sbjct: 576 CENGHTDVADVLLQAGADLDKQEDMKTILE 605
Score = 76.2 bits (179), Expect = 4e-13
Identities = 51/146 (34%), Positives = 75/146 (51%), Gaps = 2/146 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH-KANKY 170
A G + V++L+ G VN T + L AC G ++ + L+ A++ + NK
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
+ T LM A+ GYLD+V+ LL A V+ ++ G TAL +A G +V LL+ GA +
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANI 331
Query: 231 LT-NENGMTPLQCAAERARASVVEIL 255
NENG TPL AA V +L
Sbjct: 332 EDHNENGHTPLMEAASAGHVEVARVL 357
Score = 75.4 bits (177), Expect = 6e-13
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 12/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+ + T +F E +AL A GHL +V+
Sbjct: 340 TPLMEAASAGHVEVARVLLDH---GAGINTHSN-EFKE------SALTLACYKGHLDMVR 389
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++AGAD H T + T L AC +G +++ + L+ GA ++ + L +AA G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM--LTNENGMTPL 240
++++ L++ GA +++ G T L AA GH +V LL GA + T E T L
Sbjct: 450 HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETAL 509
Query: 241 QCAAERARASVVEIL 255
A + V + L
Sbjct: 510 TLACCGGFSEVADFL 524
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/136 (37%), Positives = 69/136 (50%), Gaps = 13/136 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G E V +LL + + +TE T + TAL A G +
Sbjct: 473 TPLMEAAREGHEEMVALLLAQ-GANINAQTEETQE---------TALTLACCGGFSEVAD 522
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G
Sbjct: 523 FLIKAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 183 YLDVVQFLLDSGARVD 198
+ DV LL +GA +D
Sbjct: 580 HTDVADVLLQAGADLD 595
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/135 (28%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 124 LVKAGADVNHATRTVST-PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L + A+ +H V T L AC +G ++ V+ L+ G +++ + + L +A G
Sbjct: 190 LTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAG 249
Query: 183 YLDVVQFLLDSGARVDDRALCG-ATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
Y ++ Q LL A V+DR G T L A+ G+ +V LL H A + + + G T L
Sbjct: 250 YYELAQVLLAMHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTAL 309
Query: 241 QCAAERARASVVEIL 255
A +V++L
Sbjct: 310 TYACAGGFVDIVKVL 324
Score = 36.3 bits (80), Expect = 0.35
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 24/173 (13%)
Query: 455 VEEYDSNVKTALYLVAVAGR------LLEDSGNCERWLSQGTRSAARRAVFAMRGARVRS 508
+E+++ N T L A AG LL+ ++ SA A + VR
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRF 390
Query: 509 GQTLLHLAADRNTPVDDFHTS--DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALI 566
LL AD+ D+ HT+ + C +RLLLD GA V+ + +PL +A
Sbjct: 391 ---LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 447
Query: 567 SYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLV 619
+ + L+ RGA+++ ++ +G TPL+ + E +V
Sbjct: 448 GGHVE-------------LAALLIERGANLEEVNDEGYTPLMEAAREGHEEMV 487
>AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein.
Length = 1777
Score = 90.2 bits (214), Expect = 2e-17
Identities = 60/161 (37%), Positives = 85/161 (52%), Gaps = 2/161 (1%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++ TAL AS GH+ IV+ L+K G ++ H T L AC++GR D+V+ L+ HGA
Sbjct: 75 LDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGA 134
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ Y+ ++ AA +G+ D+V LL +GA+V+ G T L +AA GH V
Sbjct: 135 NPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVKH 194
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERA-RASVVEILAARPEV 261
LL GA + N MT L A + SV EIL P V
Sbjct: 195 LLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 235
Score = 85.0 bits (201), Expect = 8e-16
Identities = 58/154 (37%), Positives = 81/154 (52%), Gaps = 1/154 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G+L IVK L+K GA+ N T L +A EG + IV+ L++ G ++
Sbjct: 44 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 103
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ T LM A YKG DVV+ LL GA L + +AA GHA +V LL
Sbjct: 104 EHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLL 163
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
+GAK+ +++ G TPL AA + V+ L A
Sbjct: 164 QNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLA 197
Score = 85.0 bits (201), Expect = 8e-16
Identities = 71/226 (31%), Positives = 110/226 (48%), Gaps = 16/226 (7%)
Query: 40 YEKKTDEIDDLLN--IDVCSDGVKCT-PLITAARHGREGAVRILLEKFRPPVCLETEGTV 96
Y+ +TD ++ LL+ + G+ P+I AA G V +LL+ C
Sbjct: 119 YKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCS------ 172
Query: 97 KFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKY 156
D+Y G T L A+ GHL VK L+ GADV+ T L A G VK
Sbjct: 173 --DKY---GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKE 227
Query: 157 LVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
+++ +++ +K NT LMIA+ +G+ ++VQ LLD+G V+ G T L A GH
Sbjct: 228 ILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGH 287
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVV-EILAARPE 260
+V +LL A + + ++ T L A E+ A++V +IL P+
Sbjct: 288 VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPD 333
Score = 75.4 bits (177), Expect = 6e-13
Identities = 47/140 (33%), Positives = 77/140 (55%), Gaps = 1/140 (0%)
Query: 117 HLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLM 176
++ +K L++ DV+ TPL A +G L+IVK L+++GA+ + + N T L+
Sbjct: 23 NIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALI 82
Query: 177 IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNEN 235
A+ +G++ +V+ LL G ++ R + G TAL +A G VV LL HGA +T
Sbjct: 83 SASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLY 142
Query: 236 GMTPLQCAAERARASVVEIL 255
+ P+ AA R A +V +L
Sbjct: 143 SVYPIIWAAGRGHADIVHLL 162
Score = 72.5 bits (170), Expect = 4e-12
Identities = 67/212 (31%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 51 LNIDVCSDGVKC-TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
+ DV +G T LI A + G +V+ +L++ P V L + +G TAL
Sbjct: 198 MGADVDQEGANSMTALIVAVKGGYTQSVKEILKR-NPNVNLTDK----------DGNTAL 246
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
AS GH IV+ L+ AG VN R+ T L A G ++IV+ L++ ADI +
Sbjct: 247 MIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQ 306
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK 229
N T L A KG +V+ +L + G T L A + + VV LLD GAK
Sbjct: 307 DNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAK 366
Query: 230 M-LTNENGMTPLQCAAERARASVVEILAARPE 260
+ ++ G TPL A + E+L P+
Sbjct: 367 VSAVDKKGDTPLHIAIRGRSRKLAELLLRNPK 398
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 4/119 (3%)
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
E + +K L+ D+ + N+ T LMIAA +G L++V+ L+ +GA + L TA
Sbjct: 21 EENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTA 80
Query: 208 LHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASVVEIL---AARPEVT 262
L A++ GH +V LL G + + G T L A + R VVE+L A P VT
Sbjct: 81 LISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVT 139
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 478 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 537
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 538 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 597
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 598 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 630
Score = 65.7 bits (153), Expect = 5e-10
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD-DRALCGATALHFAAECGHAAVVCSL 223
+K L +AA G+ DV Q + A++ R T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAKAL 498
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 CEAGCNVNIKNREGETPLLTASARGYHDIVECLA 532
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/153 (28%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHA-TRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G AL A+ GH + + A A + + T+ TPL A + G + K L G +
Sbjct: 445 GEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAKALCEAGCN 504
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +L
Sbjct: 505 VNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTL 564
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
L G + + +G TPL A + +V L
Sbjct: 565 LSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 597
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 514 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 562
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 563 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 622
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 623 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 659
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 511 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 570
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 571 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 630
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 631 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 664
Score = 58.4 bits (135), Expect = 8e-08
Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 4/129 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGH---AAVVCSLLDHGAKMLTNENGMTPLQCAAER 246
L ++ +D + G ALH AA GH A V C+ T E TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEE-ETPLHCAAWH 489
Query: 247 ARASVVEIL 255
SV + L
Sbjct: 490 GYYSVAKAL 498
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 477 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 537 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 513 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 561
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 562 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 658
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 490
Query: 249 ASVVEIL 255
SV + L
Sbjct: 491 YSVAKAL 497
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 510 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 569
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 663
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 477 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 537 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 513 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 561
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 562 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 658
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 490
Query: 249 ASVVEIL 255
SV + L
Sbjct: 491 YSVAKAL 497
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 510 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 569
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 663
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 477 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 537 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 513 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 561
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 562 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 658
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 490
Query: 249 ASVVEIL 255
SV + L
Sbjct: 491 YSVAKAL 497
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 510 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 569
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 663
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 477 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 537 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 513 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 561
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 562 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 658
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 490
Query: 249 ASVVEIL 255
SV + L
Sbjct: 491 YSVAKAL 497
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 510 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 569
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 663
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 477 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 537 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 445 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 504
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 505 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 564
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 565 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 379 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 438
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 439 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 498
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 499 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 531
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 513 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 561
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 562 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 621
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 622 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 658
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 430
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 431 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 490
Query: 249 ASVVEIL 255
SV + L
Sbjct: 491 YSVAKAL 497
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 510 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 569
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 663
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 89.8 bits (213), Expect = 3e-17
Identities = 53/153 (34%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
E T L CA+ G+ ++ K L +AG +VN R TPL A G DIV+ L HGAD
Sbjct: 480 EEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 539
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ +K + L +A + ++V++ LL G VD + G T LH A + G+ +V +L
Sbjct: 540 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 599
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + ++N+ G TPL AA VV L
Sbjct: 600 CEANCNLDISNKYGRTPLHLAANNGILDVVRYL 632
Score = 68.5 bits (160), Expect = 7e-11
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G AL A+ GH + + L G++ N + TPL A + G + K L G ++
Sbjct: 448 GEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNV 507
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N+ T L+ A+ +GY D+V+ L + GA ++ G ALH A V+ +LL
Sbjct: 508 NIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLL 567
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + + +G TPL A + +V L
Sbjct: 568 SQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 599
Score = 68.1 bits (159), Expect = 9e-11
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 1/153 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A+G G++ I++ L+K G+ ++ + S + A G +D +K+L + +
Sbjct: 382 GTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPL 441
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+K L +AA G+ DV Q L G+ + + T LH AA G+ +V +L
Sbjct: 442 DVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALC 501
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
+ G + + N G TPL A+ R +VE LA
Sbjct: 502 EAGCNVNIKNREGETPLLTASARGYHDIVECLA 534
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/157 (31%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+TA+ G V L E + +G + AL A + ++K
Sbjct: 516 TPLLTASARGYHDIVECLAEHGADLNACDKDGHI-----------ALHLAVRRCQMEVIK 564
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ G V++ R +TPL AC +G + IV L ++ +NKY T L +AA G
Sbjct: 565 TLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNG 624
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
LDVV++L GA V+ G TA A H V
Sbjct: 625 ILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHV 661
Score = 63.7 bits (148), Expect = 2e-09
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DVN + + PL A G + I++ L++ G+ I +K + + AA G++D ++F
Sbjct: 374 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKF 433
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERAR 248
L ++ +D + G ALH AA GHA V L G+ + ++ TPL CAA
Sbjct: 434 LSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGY 493
Query: 249 ASVVEIL 255
SV + L
Sbjct: 494 YSVAKAL 500
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/154 (29%), Positives = 69/154 (44%), Gaps = 1/154 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG T L AS G+ IV+ L + GAD+N + L A +++++K L+ G
Sbjct: 513 EGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCF 572
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ +++ NT L +A G + +V L ++ +D G T LH AA G VV L
Sbjct: 573 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 632
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILA 256
GA + +G T A V +LA
Sbjct: 633 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLA 666
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/153 (31%), Positives = 88/153 (57%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G L+ + L + + ++ GA+V + T L +C++G +++V+ L+ + AD
Sbjct: 259 DGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHAD 318
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ A+ + L AA++G++ VVQ L++ GA VD GATAL AA+ GH VV L
Sbjct: 319 VNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 378
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
L+HGA ++ G T ++ AA+ + ++++L
Sbjct: 379 LEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 411
Score = 88.2 bits (209), Expect = 8e-17
Identities = 54/149 (36%), Positives = 76/149 (51%), Gaps = 1/149 (0%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL + GH ++V L+ GA+V+H + TPL A +EG +D+V L+ GAD+
Sbjct: 32 ALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHT 91
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+ T L+ AA G+ VV LL GA VD G T L A+ G+ VV +LLD G
Sbjct: 92 DNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRG 151
Query: 228 A-KMLTNENGMTPLQCAAERARASVVEIL 255
+ ++ G TPL AA + E L
Sbjct: 152 LDENHRDDAGWTPLHMAAFEGHRLICEAL 180
Score = 87.8 bits (208), Expect = 1e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL + GH+ +V+ L+ ADVN A + L++A ++G + +V+ L+ HGA
Sbjct: 292 EGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAV 351
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T L IAA +G++DVVQ LL+ GA + G TA+ AA+ GH+ ++ L
Sbjct: 352 VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 411
Query: 224 LDHGAKMLTNENGMTP 239
+GA L NG +P
Sbjct: 412 EKYGASSL---NGCSP 424
Score = 87.4 bits (207), Expect = 1e-16
Identities = 69/204 (33%), Positives = 94/204 (46%), Gaps = 15/204 (7%)
Query: 28 RDGMSLTLYALLYEKKTDEIDDLLN--IDVC-SDGVKCTPLITAARHGREGAVRILLEKF 84
+DGM+ L A YE D +D LL DV +D TPL+ AA G V LL
Sbjct: 60 KDGMTPLLVAA-YEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLF-- 116
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D EG T L AS G++ +V+ L+ G D NH TPL
Sbjct: 117 ---------WGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHM 167
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A FEG I + L+ GA ++ + ++A+ +G+ D VQ LL++ + +D R G
Sbjct: 168 AAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDG 227
Query: 205 ATALHFAAECGHAAVVCSLLDHGA 228
AL AA GH +V L HGA
Sbjct: 228 RNALRVAALEGHRDIVELLFSHGA 251
Score = 85.8 bits (203), Expect = 4e-16
Identities = 55/155 (35%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GH+ +V L++ GADV+H TPL AA G +V L+ GA
Sbjct: 61 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 120
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ + T L IA+ +G ++VV+ LLD G + R G T LH AA GH + +L
Sbjct: 121 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 180
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEIL 255
++ GA+ TNE +G P A++ V+IL
Sbjct: 181 IEQGAR--TNEIDNDGRIPFILASQEGHYDCVQIL 213
Score = 85.4 bits (202), Expect = 6e-16
Identities = 56/149 (37%), Positives = 77/149 (51%), Gaps = 6/149 (4%)
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACF-----EGRLDIVKYLVRHGADIHKANKY 170
GH IV+ L+ GA+VNH T L A +G +V L+ GA++ +K
Sbjct: 2 GHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKD 61
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L++AAY+G++DVV LL+ GA VD G T L AA GHA+VV +LL GA +
Sbjct: 62 GMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 121
Query: 231 -LTNENGMTPLQCAAERARASVVEILAAR 258
+ G T L A+ + VV L R
Sbjct: 122 DSIDSEGRTVLSIASAQGNVEVVRTLLDR 150
Score = 78.6 bits (185), Expect = 7e-14
Identities = 71/232 (30%), Positives = 110/232 (47%), Gaps = 23/232 (9%)
Query: 26 AARDGMSLTLYALLYE-KKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKF 84
AA +G L AL+ + +T+EID+ DG P I A++ G V+ILLE
Sbjct: 168 AAFEGHRLICEALIEQGARTNEIDN--------DGR--IPFILASQEGHYDCVQILLEN- 216
Query: 85 RPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRA 144
D+ +G AL A+ GH IV+ L GADVN L
Sbjct: 217 ----------KSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI 266
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
E +L + +Y + +GA++ ++ T L ++ ++G++++VQ L+ A V+
Sbjct: 267 LALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEK 326
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+AL AA GH VV L++HGA + T G T L AA+ VV++L
Sbjct: 327 RSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 378
Score = 68.1 bits (159), Expect = 9e-11
Identities = 60/211 (28%), Positives = 97/211 (45%), Gaps = 15/211 (7%)
Query: 47 IDDLLNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEG 105
ID +D C DG+ TPL+ AA G V +LLE G D G
Sbjct: 49 IDRGAEVDHCDKDGM--TPLLVAAYEGHVDVVDLLLE-----------GGADVDHTDNNG 95
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
T L A+ GH ++V L+ GA V+ T L A +G +++V+ L+ G D +
Sbjct: 96 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 155
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T L +AA++G+ + + L++ GAR ++ G A++ GH V LL+
Sbjct: 156 HRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE 215
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ + + +G L+ AA +VE+L
Sbjct: 216 NKSNIDQRGYDGRNALRVAALEGHRDIVELL 246
Score = 60.5 bits (140), Expect = 2e-08
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 1/154 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH I + L++ GA N P A EG D V+ L+ + ++I
Sbjct: 161 GWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI 220
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ L +AA +G+ D+V+ L GA V+ + G L+ A + L
Sbjct: 221 DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFL 280
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
++GA + ++ G T L + + +V++L A
Sbjct: 281 ENGANVEASDAEGRTALHVSCWQGHMEMVQVLIA 314
Score = 40.7 bits (91), Expect = 0.016
Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
LLD GA+V+ D++ RT L VA + + + VV L+ RGA VD D D
Sbjct: 10 LLDHGAEVNHEDVDGRTALSVAALCVPAS--------KGHASVVSLLIDRGAEVDHCDKD 61
Query: 603 GITPLVAS 610
G+TPL+ +
Sbjct: 62 GMTPLLVA 69
Score = 36.3 bits (80), Expect = 0.35
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 542 LLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDL 601
LL+D GA+VD D + TPL VA +Y E VV LL GA VD D
Sbjct: 47 LLIDRGAEVDHCDKDGMTPLLVA--AY-----------EGHVDVVDLLLEGGADVDHTDN 93
Query: 602 DGITPLVASIGGPAESLVRSAL 623
+G TPL+A+ S+V + L
Sbjct: 94 NGRTPLLAAASMGHASVVNTLL 115
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 581 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 640
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 641 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 700
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 701 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 740
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 607 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 655
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 656 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 715
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 716 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 775
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 776 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 808
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 584 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 633
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 634 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 693
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 694 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 753
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 754 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 799
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 686 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 735
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 736 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 795
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 796 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 855
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 856 LMSAFRKGHVKVVQYL 871
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/176 (35%), Positives = 83/176 (47%), Gaps = 23/176 (13%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L AS GHL +VK L+ +GA+V+ T T T L AC G D+ L++ GAD+
Sbjct: 11 STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLD 70
Query: 166 K-------------------ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG-- 204
K ++ T LM AA G+L VQFL+ GA V +RA
Sbjct: 71 KQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANV-NRATANND 129
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
T + A GH AVV LL HGA ++G T L AA+ +VV L P
Sbjct: 130 HTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYP 185
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 551 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 610
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 611 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 670
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 671 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 703
Score = 64.5 bits (150), Expect = 1e-09
Identities = 43/105 (40%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Query: 90 LETEGTVKFDEYVIEGA-TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACF 147
LE K E+ EG T L A+ AGHL V+ L+ GA+VN AT T + AC
Sbjct: 79 LEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACA 138
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
G L +V+ L+ HGAD K +T L+ AA G+ +VV +LLD
Sbjct: 139 GGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 183
Score = 61.7 bits (143), Expect = 8e-09
Identities = 51/153 (33%), Positives = 68/153 (44%), Gaps = 24/153 (15%)
Query: 126 KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLD 185
KAGAD+ STPL A EG L++VKYL+ GA++H +T L A G+ D
Sbjct: 1 KAGADIELGC---STPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTD 57
Query: 186 VVQFLLDSGARVDDR-------------------ALCGATALHFAAECGHAAVVCSLLDH 226
V LL +GA +D + + G T L AA GH V L+
Sbjct: 58 VADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISK 117
Query: 227 GAKM--LTNENGMTPLQCAAERARASVVEILAA 257
GA + T N T + A +VVE+L A
Sbjct: 118 GANVNRATANNDHTVVSLACAGGHLAVVELLLA 150
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/148 (33%), Positives = 72/148 (48%), Gaps = 20/148 (13%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVN-------------------HATRTVSTPLRAA 145
G TAL A GH + L++AGAD++ H + TPL A
Sbjct: 43 GDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKA 102
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
G L V++L+ GA++++A N+ T + +A G+L VV+ LL GA R G
Sbjct: 103 ARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDG 162
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLT 232
+T L AA+ GH VV LLD+ +L+
Sbjct: 163 STMLIEAAKGGHTNVVSYLLDYPNNVLS 190
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 753 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 803
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 804 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 863
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 864 HVKVVQYLV 872
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 818 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 873
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 542 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 600
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 601 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 638
Score = 42.3 bits (95), Expect = 0.005
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T D V+ +L CA GHLA+V+
Sbjct: 97 TPLMKAARAGHLCTVQFLISK----GANVNRATANNDHTVV----SLACA--GGHLAVVE 146
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G ++V YL+
Sbjct: 147 LLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 182
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 764 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 810
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 811 HIDVRNKKGNTPLWLASNGG 830
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 298 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 357
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 358 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 417
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 418 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 457
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 324 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 372
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 373 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 432
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 433 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 492
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 493 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 525
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 301 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 350
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 351 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 410
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 411 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 470
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 471 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 516
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 403 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 452
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 453 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 512
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 513 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 572
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 573 LMSAFRKGHVKVVQYL 588
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 268 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 327
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 328 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 387
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 388 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 420
Score = 68.1 bits (159), Expect = 9e-11
Identities = 61/170 (35%), Positives = 80/170 (47%), Gaps = 23/170 (13%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK----- 166
AS GHL +VK L+ +GA+V+ T T T L AC G D+ L++ GAD+ K
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMK 62
Query: 167 --------------ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHF 210
++ T LM AA G+L VQFL+ GA V +RA T +
Sbjct: 63 TILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANV-NRATANNDHTVVSL 121
Query: 211 AAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQCAAERARASVVEILAARP 259
A GH AVV LL HGA ++G T L AA+ +VV L P
Sbjct: 122 ACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYP 171
Score = 64.5 bits (150), Expect = 1e-09
Identities = 43/105 (40%), Positives = 57/105 (54%), Gaps = 2/105 (1%)
Query: 90 LETEGTVKFDEYVIEGA-TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACF 147
LE K E+ EG T L A+ AGHL V+ L+ GA+VN AT T + AC
Sbjct: 65 LEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACA 124
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
G L +V+ L+ HGAD K +T L+ AA G+ +VV +LLD
Sbjct: 125 GGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 169
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/148 (33%), Positives = 72/148 (48%), Gaps = 20/148 (13%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVN-------------------HATRTVSTPLRAA 145
G TAL A GH + L++AGAD++ H + TPL A
Sbjct: 29 GDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKA 88
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
G L V++L+ GA++++A N+ T + +A G+L VV+ LL GA R G
Sbjct: 89 ARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDG 148
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLT 232
+T L AA+ GH VV LLD+ +L+
Sbjct: 149 STMLIEAAKGGHTNVVSYLLDYPNNVLS 176
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 470 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 520
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 521 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 580
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 581 HVKVVQYLV 589
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 535 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 590
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 259 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 317
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 318 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 355
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/66 (40%), Positives = 38/66 (57%)
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN 235
M A+ +G+L++V++LL SGA V G TAL +A E GH V LL GA + E+
Sbjct: 1 MEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQED 60
Query: 236 GMTPLQ 241
T L+
Sbjct: 61 MKTILE 66
Score = 42.3 bits (95), Expect = 0.005
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AAR G V+ L+ K T D V+ +L CA GHLA+V+
Sbjct: 83 TPLMKAARAGHLCTVQFLISK----GANVNRATANNDHTVV----SLACA--GGHLAVVE 132
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
L+ GAD H + ST L A G ++V YL+
Sbjct: 133 LLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLL 168
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 481 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 527
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 528 HIDVRNKKGNTPLWLASNGG 547
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 89.0 bits (211), Expect = 5e-17
Identities = 60/162 (37%), Positives = 89/162 (54%), Gaps = 9/162 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVN-HATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ AGH+ +V+ L+ G D+ + RT TPL AC GR ++V L+ GA
Sbjct: 164 KGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGA 223
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR--ALCGATALHFAAECGHAAVV 220
+ N + T L +AA GY+++++ LL++GA ++ R + G + L AA GH V
Sbjct: 224 NKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAV 283
Query: 221 CSLLDHG----AKMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G A++ TN N T L A + RA VV +L R
Sbjct: 284 KLLLDMGSDINAQIETNRN--TALTLACFQGRAEVVSLLLDR 323
Score = 83.8 bits (198), Expect = 2e-15
Identities = 71/213 (33%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+I+ S+ K TPL A GR+ V +LL + G K + + T L
Sbjct: 190 DIEAQSERTKDTPLSLACSGGRQEVVDLLLAR----------GANK-EHRNVSDYTPLSL 238
Query: 112 ASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G++ I+K L+ AGA++N T + +PL A G + VK L+ G+DI+ +
Sbjct: 239 AASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIE 298
Query: 170 YN-NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
N NT L +A ++G +VV LLD A V+ RA G T L AA G+A V LLD GA
Sbjct: 299 TNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGA 358
Query: 229 KM---LTNENGMTPLQCAAERARASVVEILAAR 258
+ + T L AA++ E+L R
Sbjct: 359 DVNAPPVPSSRDTALTIAADKGHYKFCELLIHR 391
Score = 81.0 bits (191), Expect = 1e-14
Identities = 72/226 (31%), Positives = 105/226 (46%), Gaps = 14/226 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPLI AA G G V ILL+K + ++E T T L A G +V
Sbjct: 167 TPLILAATAGHVGVVEILLDK-GGDIEAQSERTKD---------TPLSLACSGGRQEVVD 216
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ GA+ H + TPL A G ++I+K L+ GA+I+ +K + LM+AA
Sbjct: 217 LLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAM 276
Query: 181 KGYLDVVQFLLDSGARVDDRALCGA-TALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMT 238
G++ V+ LLD G+ ++ + TAL A G A VV LLD A + + G+T
Sbjct: 277 NGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLT 336
Query: 239 PLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
PL AA A V +L + A + + + A DK +Y
Sbjct: 337 PLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKGHY 382
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/196 (31%), Positives = 91/196 (46%), Gaps = 13/196 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL+ AA +G AV++LL+ G+ + TAL A G +V
Sbjct: 269 SPLMLAAMNGHVPAVKLLLDM----------GSDINAQIETNRNTALTLACFQGRAEVVS 318
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANKYNNTCLMIAAY 180
L+ A+V H +T TPL A G ++ + L+ GAD++ +T L IAA
Sbjct: 319 LLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAAD 378
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTP 239
KG+ + L+ GA +D R G T L A+ GH VV L+ GA + +N +TP
Sbjct: 379 KGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITP 438
Query: 240 LQCAAERARASVVEIL 255
L A + VV+ L
Sbjct: 439 LMSAFRKGHVKVVQYL 454
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/153 (30%), Positives = 76/153 (49%), Gaps = 4/153 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH- 165
TAL A GH +V L+ A + H + TPL A G + +V+ L+ G DI
Sbjct: 134 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 193
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
++ + +T L +A G +VV LL GA + R + T L AA G+ ++ LL+
Sbjct: 194 QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLN 253
Query: 226 HGAKMLT---NENGMTPLQCAAERARASVVEIL 255
GA++ + ++ G++PL AA V++L
Sbjct: 254 AGAEINSRTGSKLGISPLMLAAMNGHVPAVKLL 286
Score = 58.4 bits (135), Expect = 8e-08
Identities = 43/129 (33%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ AA G R+LL+K V TAL A+ GH +
Sbjct: 336 TPLMEAASGGYAEVGRVLLDK---------GADVNAPPVPSSRDTALTIAADKGHYKFCE 386
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ + +TPL A G D+V+ LV+ GAD+ A+ T LM A KG
Sbjct: 387 LLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKG 446
Query: 183 YLDVVQFLL 191
++ VVQ+L+
Sbjct: 447 HVKVVQYLV 455
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/56 (46%), Positives = 37/56 (66%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVR 159
+G T LW AS GH +V+ LV+AGADV+ A TPL +A +G + +V+YLV+
Sbjct: 401 KGNTPLWLASNGGHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVK 456
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D H + ++ T L +A G+ ++V L+ A+++ R G T L AA GH VV
Sbjct: 125 DAHTESNHD-TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEI 183
Query: 223 LLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
LLD G + + TPL A R VV++L AR
Sbjct: 184 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLAR 221
Score = 37.1 bits (82), Expect = 0.20
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 16/80 (20%)
Query: 537 ARTSRLLLDCGADVDAADM--NRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGA 594
A R+LLD GADV+A + +R T L +A D+ Y FC + L+ RGA
Sbjct: 347 AEVGRVLLDKGADVNAPPVPSSRDTALTIAA--------DKGHYK--FCEL---LIHRGA 393
Query: 595 HVDAMDLDGITPL-VASIGG 613
H+D + G TPL +AS GG
Sbjct: 394 HIDVRNKKGNTPLWLASNGG 413
>AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein
protein.
Length = 1031
Score = 87.0 bits (206), Expect = 2e-16
Identities = 60/162 (37%), Positives = 86/162 (53%), Gaps = 3/162 (1%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++ TAL AS GH+ IV+ L+K G ++ H T L AC++GR D+V+ L+ HGA
Sbjct: 69 LDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGA 128
Query: 163 DIHKAN-KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ +Y+ ++ AA +G+ D+V LL +GA+V+ G T L +AA GH V
Sbjct: 129 NPSVTGLQYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLECVK 188
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERA-RASVVEILAARPEV 261
LL GA + N MT L A + SV EIL P V
Sbjct: 189 HLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNV 230
Score = 86.6 bits (205), Expect = 2e-16
Identities = 72/227 (31%), Positives = 108/227 (47%), Gaps = 17/227 (7%)
Query: 40 YEKKTDEIDDLL----NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGT 95
Y+ +TD ++ LL N V P+I AA G V +LL+ C
Sbjct: 113 YKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLLLQNGAKVNCS----- 167
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
D+Y G T L A+ GHL VK L+ GADV+ T L A G VK
Sbjct: 168 ---DKY---GTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVK 221
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
+++ +++ +K NT LMIA+ +G+ ++VQ LLD+G V+ G T L A G
Sbjct: 222 EILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGG 281
Query: 216 HAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVV-EILAARPE 260
H +V +LL A + + ++ T L A E+ A++V +IL P+
Sbjct: 282 HVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPD 328
Score = 80.6 bits (190), Expect = 2e-14
Identities = 58/155 (37%), Positives = 81/155 (52%), Gaps = 2/155 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G+L IVK L+K GA+ N T L +A EG + IV+ L++ G ++
Sbjct: 38 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 97
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRAL-CGATALHFAAECGHAAVVCSL 223
+ T LM A YKG DVV+ LL GA L + +AA GHA +V L
Sbjct: 98 EHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLL 157
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILAA 257
L +GAK+ +++ G TPL AA + V+ L A
Sbjct: 158 LQNGAKVNCSDKYGTTPLVWAARKGHLECVKHLLA 192
Score = 72.9 bits (171), Expect = 3e-12
Identities = 46/141 (32%), Positives = 76/141 (53%), Gaps = 2/141 (1%)
Query: 117 HLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLM 176
++ +K L++ DV+ TPL A +G L+IVK L+++GA+ + + N T L+
Sbjct: 17 NIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALI 76
Query: 177 IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN--E 234
A+ +G++ +V+ LL G ++ R + G TAL +A G VV LL HGA +
Sbjct: 77 SASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQ 136
Query: 235 NGMTPLQCAAERARASVVEIL 255
+ P+ AA R A +V +L
Sbjct: 137 YSVYPIIWAAGRGHADIVHLL 157
Score = 72.5 bits (170), Expect = 4e-12
Identities = 67/212 (31%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 51 LNIDVCSDGVKC-TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
+ DV +G T LI A + G +V+ +L++ P V L + +G TAL
Sbjct: 193 MGADVDQEGANSMTALIVAVKGGYTQSVKEILKR-NPNVNLTDK----------DGNTAL 241
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
AS GH IV+ L+ AG VN R+ T L A G ++IV+ L++ ADI +
Sbjct: 242 MIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQ 301
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK 229
N T L A KG +V+ +L + G T L A + + VV LLD GAK
Sbjct: 302 DNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAK 361
Query: 230 M-LTNENGMTPLQCAAERARASVVEILAARPE 260
+ ++ G TPL A + E+L P+
Sbjct: 362 VSAVDKKGDTPLHIAIRGRSRKLAELLLRNPK 393
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 4/119 (3%)
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
E + +K L+ D+ + N+ T LMIAA +G L++V+ L+ +GA + L TA
Sbjct: 15 EENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTA 74
Query: 208 LHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASVVEIL---AARPEVT 262
L A++ GH +V LL G + + G T L A + R VVE+L A P VT
Sbjct: 75 LISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVT 133
>AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens
cDNA FLJ42568 fis, clone BRACE3007625, moderately
similar to Rattus norvegicus espin (Espn). ).
Length = 1005
Score = 87.0 bits (206), Expect = 2e-16
Identities = 73/205 (35%), Positives = 100/205 (48%), Gaps = 18/205 (8%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D +PL AAR G V LL + LET EGA L A+ +G
Sbjct: 101 DASGVSPLHLAARFGHPVLVEWLLHEGHSAT-LETR----------EGARPLHHAAVSGD 149
Query: 118 LAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCL 175
L +K L A G+ VN TR+ ++PL AC EG L + ++LV+ GAD+H + L
Sbjct: 150 LTCLKLLTAAHGSSVNRRTRSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSAL 209
Query: 176 MIAAYKGYLDVVQFLL---DSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
AA +G+ +V +L+ D G D GATALHFAA GH ++ LL G +L
Sbjct: 210 HAAAARGHYSLVVWLVTFTDIGLTARDNE--GATALHFAARGGHTPILDRLLLMGTPILR 267
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ G TPL AAE + + L +
Sbjct: 268 DSWGGTPLHDAAENGQMECCQTLVS 292
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/171 (32%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEG 149
L EG + G + L A+ GH +V+ L+ G TR + PL A G
Sbjct: 89 LVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEGHSATLETREGARPLHHAAVSG 148
Query: 150 RLDIVKYL-VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATA 207
L +K L HG+ +++ + + L +A +G+L + QFL+ D GA V RAL G +A
Sbjct: 149 DLTCLKLLTAAHGSSVNRRTRSGASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSA 208
Query: 208 LHFAAECGHAAVVCSLL---DHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LH AA GH ++V L+ D G NE G T L AA +++ L
Sbjct: 209 LHAAAARGHYSLVVWLVTFTDIGLTARDNE-GATALHFAARGGHTPILDRL 258
Score = 50.4 bits (115), Expect = 2e-05
Identities = 48/143 (33%), Positives = 65/143 (45%), Gaps = 6/143 (4%)
Query: 105 GATALWCASGAGHLAIVKRLVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
GA+ L+ A GHL + + LVK GADV+ + L AA G +V +LV D
Sbjct: 171 GASPLYLACQEGHLHLAQFLVKDCGADVHLRALDGMSALHAAAARGHYSLVVWLVTF-TD 229
Query: 164 IHKANKYNN--TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
I + N T L AA G+ ++ LL G + R G T LH AAE G
Sbjct: 230 IGLTARDNEGATALHFAARGGHTPILDRLLLMGTPIL-RDSWGGTPLHDAAENGQMECCQ 288
Query: 222 SLLDHGA-KMLTNENGMTPLQCA 243
+L+ H L +E+G T A
Sbjct: 289 TLVSHHVDPSLRDEDGYTAADLA 311
Score = 48.8 bits (111), Expect = 6e-05
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPL-RAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G +A ++RL++AGA T + L A G LD VK+LV+ +
Sbjct: 9 AAKDGDVATLERLLEAGALGPGITDALGAGLVHHATRAGHLDCVKFLVQRAQLPGNQRAH 68
Query: 171 NN-TCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG- 227
N T AA G L + +L+ + G + D+ G + LH AA GH +V LL G
Sbjct: 69 NGATPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEGH 128
Query: 228 AKMLTNENGMTPLQCAAERARASVVEILAA 257
+ L G PL AA + +++L A
Sbjct: 129 SATLETREGARPLHHAAVSGDLTCLKLLTA 158
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EGATAL A+ GH I+ RL+ G + + TPL A G+++ + LV H D
Sbjct: 238 EGATALHFAARGGHTPILDRLLLMGTPILRDSWG-GTPLHDAAENGQMECCQTLVSHHVD 296
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFL 190
++ T +A Y G+ D Q+L
Sbjct: 297 PSLRDEDGYTAADLAEYHGHRDCAQYL 323
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 86.6 bits (205), Expect = 2e-16
Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ + I L++ GAD N TR + A EG +D+V L+ A++
Sbjct: 175 GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 234
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +NK T L +AA + ++V + L++ GA VD + G T LH G+ +V LL
Sbjct: 235 NLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLL 294
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
H AK+ +NG TPL AA++ ++ +L
Sbjct: 295 QHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 326
Score = 84.2 bits (199), Expect = 1e-15
Identities = 68/222 (30%), Positives = 102/222 (45%), Gaps = 14/222 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G E LL+ + + T+ +G T L A+ G L +
Sbjct: 78 TPLHLSAREGHEDVAAFLLDH-GASLSITTK----------KGFTPLHVAAKYGKLEVAN 126
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ A + A ++ TPL A + L+ GA H A K T L IAA K
Sbjct: 127 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKN 186
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+D+ LL+ GA + G ++H AA+ GH +V LL A + L+N++G+TPL
Sbjct: 187 QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH 246
Query: 242 CAAERARASVVEILAARPEVTRAEAIEAYELL--GASFANDK 281
AA+ R +V E+L + A+ Y L G + N K
Sbjct: 247 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 288
Score = 83.8 bits (198), Expect = 2e-15
Identities = 47/124 (37%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 133 HATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
H + T L A G+ ++V+YLV+ GA + K + T L I+A G D+VQ LL
Sbjct: 5 HVPQRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQ 64
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV 251
GA + G T LH +A GH V LLDHGA + +T + G TPL AA+ + V
Sbjct: 65 QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEV 124
Query: 252 VEIL 255
+L
Sbjct: 125 ANLL 128
Score = 83.0 bits (196), Expect = 3e-15
Identities = 57/167 (34%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +G +V+ LV+ GA V + TPL + G+ DIV+ L++ GA
Sbjct: 10 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASP 69
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ A T L ++A +G+ DV FLLD GA + G T LH AA+ G V LL
Sbjct: 70 NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLL 129
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAY 270
A ++G+TPL AA V +L + A A Y
Sbjct: 130 QKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY 176
Score = 79.8 bits (188), Expect = 3e-14
Identities = 53/162 (32%), Positives = 81/162 (50%), Gaps = 5/162 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G ++ A+ GH+ +V L+ A+VN + ++ TPL A E R+++ + LV GA
Sbjct: 207 QGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAH 266
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ K T L + + G + +V FLL A+V+ + G T LH AA+ GH ++ L
Sbjct: 267 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 326
Query: 224 LDHGAKMLTNE---NGMTPLQCAAERARASVVEILAARPEVT 262
L + A NE NG T L A SVV+ L E T
Sbjct: 327 LQNNAS--PNELTVNGNTALGIARRLGYISVVDTLKIVTEET 366
Score = 71.3 bits (167), Expect = 1e-11
Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 12/197 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +AR G+ V+ LL++ P T G T L ++ GH +
Sbjct: 45 TPLHISARLGKADIVQQLLQQGASPNAATTSGY-----------TPLHLSAREGHEDVAA 93
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA ++ T+ TPL A G+L++ L++ A A K T L +AA+
Sbjct: 94 FLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 153
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
V LLD GA A G T LH AA+ + +LL++GA G+ +
Sbjct: 154 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 213
Query: 242 CAAERARASVVEILAAR 258
AA+ +V +L R
Sbjct: 214 LAAQEGHVDMVSLLLGR 230
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 85.0 bits (201), Expect = 8e-16
Identities = 50/153 (32%), Positives = 74/153 (48%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G T L A+ G + +L++ ADVN T + GR +++ LV+H +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + T L +A G+ VQ LLDSGA ++ + GAT L+FA G
Sbjct: 156 DVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 215
Query: 223 LLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL GAK L ++NG+TPL + E+L
Sbjct: 216 LLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVL 248
Score = 69.7 bits (163), Expect = 3e-11
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 1/151 (0%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ G + + L+K GA+ N+ + TPL A G+ + L+ + AD++ N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
T + A G +++ L+ + VD G TALH A + GH V LLD GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGA 188
Query: 229 KM-LTNENGMTPLQCAAERARASVVEILAAR 258
+ N +G TPL A + +IL R
Sbjct: 189 DINRPNVSGATPLYFACSHGQRDTAQILLLR 219
Score = 55.6 bits (128), Expect = 5e-07
Identities = 56/200 (28%), Positives = 86/200 (43%), Gaps = 14/200 (7%)
Query: 62 CTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIV 121
CTPL AAR+G++ + LLE + V + EG TA+ + G ++
Sbjct: 99 CTPLHLAARNGQKKCMSKLLE-YSADVNICNN----------EGLTAIHWLAVNGRTELL 147
Query: 122 KRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
LV+ +DV+ T L AC G V+ L+ GADI++ N T L A
Sbjct: 148 HDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSH 207
Query: 182 GYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPL 240
G D Q LL GA+ + D+ G T L + G+ L+ + ++ MT
Sbjct: 208 GQRDTAQILLLRGAKYLPDKN--GVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQN 265
Query: 241 QCAAERARASVVEILAARPE 260
+ E V+E L+ + E
Sbjct: 266 EDLRENMLRQVLEHLSQQSE 285
Score = 41.1 bits (92), Expect = 0.012
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 163 DIHKA-NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D++ A + + L IAA G ++ + LL GA + + + G T LH AA G +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMS 115
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL++ A + + N G+T + A R ++ L
Sbjct: 116 KLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDL 150
>BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III and
ankyrin repeat domains 1 protein.
Length = 345
Score = 85.0 bits (201), Expect = 8e-16
Identities = 57/165 (34%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Query: 94 GTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDI 153
G VK D G TAL A+ G+ +VK LV G DVN + L AC+ G LD+
Sbjct: 133 GRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDV 192
Query: 154 VKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD--DRALCGATALHFA 211
VKYL RHGA + T L AA G+ V+++++ G VD D + +
Sbjct: 193 VKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS 252
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
A G+ V L+D GA + + + NG TPL A +V++L
Sbjct: 253 AVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLL 297
Score = 57.2 bits (132), Expect = 2e-07
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHA-TRTVSTPL-RAACFEGRLDIVKYLVRHGA 162
G TAL A+ GH ++++ ++K G +V+ T + TPL R + G + L+ GA
Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGA 269
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ ++ T LM+A + ++VQ LLD GA + G L A +VV S
Sbjct: 270 NVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVV-S 328
Query: 223 LLDHGAK 229
LL+ K
Sbjct: 329 LLEERKK 335
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 153 IVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
+V+ L + NK+ T LM+AA KGY +V+ L+ +G V+ + G +L A
Sbjct: 126 LVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLAC 185
Query: 213 ECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASVVE 253
GH VV L HGA + G T L AA+ SV+E
Sbjct: 186 YAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIE 227
Score = 33.5 bits (73), Expect = 2.4
Identities = 14/30 (46%), Positives = 22/30 (73%)
Query: 538 RTSRLLLDCGADVDAADMNRRTPLHVALIS 567
R + LL+D GA+V+ D N +TPL VA+++
Sbjct: 259 RVASLLIDAGANVNVKDRNGKTPLMVAVLN 288
>AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein.
Length = 371
Score = 85.0 bits (201), Expect = 8e-16
Identities = 57/165 (34%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Query: 94 GTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDI 153
G VK D G TAL A+ G+ +VK LV G DVN + L AC+ G LD+
Sbjct: 159 GRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDV 218
Query: 154 VKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD--DRALCGATALHFA 211
VKYL RHGA + T L AA G+ V+++++ G VD D + +
Sbjct: 219 VKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVS 278
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
A G+ V L+D GA + + + NG TPL A +V++L
Sbjct: 279 AVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLL 323
Score = 57.2 bits (132), Expect = 2e-07
Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 3/188 (1%)
Query: 68 AARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKA 127
A +H EG L +FR V G ++ V T + + +V ++
Sbjct: 67 ATKHVVEGLEPRTLYRFRLKVT-SPSGECEYSPLVSVSTTRPSLSKSLVKIRMVTSVLHG 125
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIHKANKYNNTCLMIAAYKGYLDV 186
N S L A D++ +++ G + NK+ T LM+AA KGY +
Sbjct: 126 PPTENTGEPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRL 185
Query: 187 VQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAE 245
V+ L+ +G V+ + G +L A GH VV L HGA + G T L AA+
Sbjct: 186 VKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAAD 245
Query: 246 RARASVVE 253
SV+E
Sbjct: 246 GGHCSVIE 253
Score = 57.2 bits (132), Expect = 2e-07
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHA-TRTVSTPL-RAACFEGRLDIVKYLVRHGA 162
G TAL A+ GH ++++ ++K G +V+ T + TPL R + G + L+ GA
Sbjct: 236 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGA 295
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+++ ++ T LM+A + ++VQ LLD GA + G L A +VV S
Sbjct: 296 NVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVV-S 354
Query: 223 LLDHGAK 229
LL+ K
Sbjct: 355 LLEERKK 361
Score = 33.5 bits (73), Expect = 2.4
Identities = 14/30 (46%), Positives = 22/30 (73%)
Query: 538 RTSRLLLDCGADVDAADMNRRTPLHVALIS 567
R + LL+D GA+V+ D N +TPL VA+++
Sbjct: 285 RVASLLIDAGANVNVKDRNGKTPLMVAVLN 314
>BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 360
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 183 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 242
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 243 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 302
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 303 GADMMTKNLAGKTP 316
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 155 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 214
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 215 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 264
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 155 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 214
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 215 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 274
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 275 ARDREGDTALHDAVRLNRYKIIKLL 299
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 248 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 307
Query: 166 KANKYNNT 173
N T
Sbjct: 308 TKNLAGKT 315
>AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 156 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 215
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 276 GADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 247
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 248 ARDREGDTALHDAVRLNRYKIIKLL 272
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 221 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 280
Query: 166 KANKYNNT 173
N T
Sbjct: 281 TKNLAGKT 288
>AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 156 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 215
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 276 GADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 247
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 248 ARDREGDTALHDAVRLNRYKIIKLL 272
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 221 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 280
Query: 166 KANKYNNT 173
N T
Sbjct: 281 TKNLAGKT 288
>AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein
protein.
Length = 449
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 272 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 331
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 332 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 391
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 392 GADMMTKNLAGKTP 405
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 244 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 303
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 304 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 353
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 244 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 303
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 304 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 363
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 364 ARDREGDTALHDAVRLNRYKIIKLL 388
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 337 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 396
Query: 166 KANKYNNT 173
N T
Sbjct: 397 TKNLAGKT 404
>AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin
protein 2 protein.
Length = 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 156 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 215
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 276 GADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 247
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 248 ARDREGDTALHDAVRLNRYKIIKLL 272
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 221 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 280
Query: 166 KANKYNNT 173
N T
Sbjct: 281 TKNLAGKT 288
>AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin
repeat protein.
Length = 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 156 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 215
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 276 GADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 247
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 248 ARDREGDTALHDAVRLNRYKIIKLL 272
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 221 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 280
Query: 166 KANKYNNT 173
N T
Sbjct: 281 TKNLAGKT 288
>AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein
protein.
Length = 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 51/134 (38%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL AS GH+ I+++L+ GA V+ R T + AC G L++VK L HGAD +
Sbjct: 156 TALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNV 215
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A G +++V+ L G ++ R G TALH A ++ LL H
Sbjct: 216 RDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLH 275
Query: 227 GAKMLT-NENGMTP 239
GA M+T N G TP
Sbjct: 276 GADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A EG++ +++ + G +++ T L A+ +G++++++ LLD+GA VD +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVE 253
TA+H+A GH VV L HGA + + TPL A + +VE
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237
Score = 55.2 bits (127), Expect = 7e-07
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G + ++++ + G + + T L A EG ++I++ L+ +GA + ++ +
Sbjct: 128 AAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLD 187
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM- 230
T + A G+L+VV+ L GA + R +T LH A G +V L G ++
Sbjct: 188 CTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN 247
Query: 231 LTNENGMTPLQCAAERARASVVEIL 255
+ G T L A R ++++L
Sbjct: 248 ARDREGDTALHDAVRLNRYKIIKLL 272
Score = 37.1 bits (82), Expect = 0.20
Identities = 22/68 (32%), Positives = 31/68 (45%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A G + IV+ + G ++N R T L A R I+K L+ HGAD+
Sbjct: 221 STPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMM 280
Query: 166 KANKYNNT 173
N T
Sbjct: 281 TKNLAGKT 288
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 83.8 bits (198), Expect = 2e-15
Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K LVKAGA+V + +T L AC + L+ G+
Sbjct: 107 DGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 166
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 167 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTR 263
L+ GA + N G TPL+ A V +L P+V R
Sbjct: 227 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLR 267
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/152 (32%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GHL +V+ L+KAG D++ T L A G +I+ L+ G +
Sbjct: 42 GRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCAL 101
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +K NT L A++ G+ + L+ +GA V + G TALH A + H+ LL
Sbjct: 102 DRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLL 161
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G++ L N G T L AA S++ +L
Sbjct: 162 LAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 193
Score = 68.5 bits (160), Expect = 7e-11
Identities = 67/230 (29%), Positives = 104/230 (45%), Gaps = 18/230 (7%)
Query: 31 MSLTLYALLYEKKTDEIDDLLN----IDVCSDGVKCTPLITAARHGREGAVRILLEKFRP 86
+S L Y+ +T+ + L+N + V G TPL AA G V+ILL K
Sbjct: 10 LSERLLVAAYKGQTENVVQLINKGARVAVTKHGR--TPLHLAANKGHLPVVQILL-KAGC 66
Query: 87 PVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC 146
+ ++ +G D+ TAL A+ G+ I+ L+ G ++ + +T L A
Sbjct: 67 DLDVQDDG----DQ------TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEAS 116
Query: 147 FEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGAT 206
+ G K LV+ GA++ NK NT L +A + + LL +G+R D + G T
Sbjct: 117 WHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT 176
Query: 207 ALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH AA H +++ LL + N+ G T L AA V +IL
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
>AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein
protein.
Length = 641
Score = 83.8 bits (198), Expect = 2e-15
Identities = 55/161 (34%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K LVKAGA+V + +T L AC + L+ G+
Sbjct: 21 DGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 80
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 81 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 140
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTR 263
L+ GA + N G TPL+ A V +L P+V R
Sbjct: 141 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLR 181
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
I+ L+ G ++ + +T L A + G K LV+ GA++ NK NT L +A
Sbjct: 4 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLAC 63
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
+ + LL +G+R D + G T LH AA H +++ LL + N+ G T
Sbjct: 64 QNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDT 123
Query: 239 PLQCAAERARASVVEIL 255
L AA V +IL
Sbjct: 124 ALHVAAALNHKKVAKIL 140
Score = 51.2 bits (117), Expect = 1e-05
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+I+ L+ G + + +K NT L A++ G+ + L+ +GA V + G TALH A
Sbjct: 3 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLA 62
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ H+ LL G++ L N G T L AA S++ +L
Sbjct: 63 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 107
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 83.8 bits (198), Expect = 2e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 506 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGRTPMHVACQHGQENIVR 554
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 555 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 614
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 615 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTAL 674
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 675 HLAARNGHLATVKLL 689
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 595 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 655 LLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 715 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 754
Score = 78.6 bits (185), Expect = 7e-14
Identities = 71/216 (32%), Positives = 98/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 539 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 587
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 588 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 647
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA G TALH AA GH A V L++ A +L T L
Sbjct: 648 GHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 707
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 708 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 737
Score = 76.2 bits (179), Expect = 4e-13
Identities = 55/175 (31%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R +A + Y L + N
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARN 680
Score = 64.9 bits (151), Expect = 9e-10
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 606 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 654
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 655 LLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 715 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 759
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G TP+ A + +
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 550 ENIVRILLRR 559
Score = 41.5 bits (93), Expect = 0.009
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE+L AR
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 498 NAKDEDQWTALHFAAQNGDE 517
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 506 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGRTPMHVACQHGQENIVR 554
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 555 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 614
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 615 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTAL 674
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 675 HLAARNGHLATVKLL 689
Score = 79.8 bits (188), Expect = 3e-14
Identities = 71/216 (32%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 539 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 587
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 588 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 647
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA + G TALH AA GH A V L++ A +L T L
Sbjct: 648 GHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 707
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 708 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 737
Score = 79.8 bits (188), Expect = 3e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 595 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 715 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 754
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/175 (31%), Positives = 82/175 (46%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R A + Y L + N
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARN 680
Score = 64.9 bits (151), Expect = 9e-10
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 606 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 654
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 715 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 759
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G TP+ A + +
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 550 ENIVRILLRR 559
Score = 41.5 bits (93), Expect = 0.009
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE+L AR
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 498 NAKDEDQWTALHFAAQNGDE 517
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 506 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGRTPMHVACQHGQENIVR 554
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 555 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 614
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 615 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTAL 674
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 675 HLAARNGHLATVKLL 689
Score = 79.8 bits (188), Expect = 3e-14
Identities = 71/216 (32%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 539 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 587
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 588 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 647
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA + G TALH AA GH A V L++ A +L T L
Sbjct: 648 GHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 707
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 708 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 737
Score = 79.8 bits (188), Expect = 3e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 595 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 715 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 754
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/175 (31%), Positives = 82/175 (46%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R A + Y L + N
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARN 680
Score = 64.9 bits (151), Expect = 9e-10
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 606 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 654
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 715 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 759
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G TP+ A + +
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 550 ENIVRILLRR 559
Score = 41.5 bits (93), Expect = 0.009
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE+L AR
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 498 NAKDEDQWTALHFAAQNGDE 517
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/161 (33%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K L+KAGA+V + +T L AC + L+ G+
Sbjct: 20 DGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 79
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 80 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 139
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTR 263
L+ GA + N G TPL+ A V +L P+V R
Sbjct: 140 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLR 180
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
I+ L+ G ++ + +T L A + G K L++ GA++ NK NT L +A
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLAC 62
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
+ + LL +G+R D + G T LH AA H +++ LL + N+ G T
Sbjct: 63 QNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDT 122
Query: 239 PLQCAAERARASVVEIL 255
L AA V +IL
Sbjct: 123 ALHVAAALNHKKVAKIL 139
Score = 51.6 bits (118), Expect = 9e-06
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+I+ L+ G + + +K NT L A++ G+ + L+ +GA V + G TALH A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ H+ LL G++ L N G T L AA S++ +L
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 106
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/161 (33%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K L+KAGA+V + +T L AC + L+ G+
Sbjct: 20 DGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 79
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 80 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 139
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTR 263
L+ GA + N G TPL+ A V +L P+V R
Sbjct: 140 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLR 180
Score = 59.7 bits (138), Expect = 3e-08
Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
I+ L+ G ++ + +T L A + G K L++ GA++ NK NT L +A
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLAC 62
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
+ + LL +G+R D + G T LH AA H +++ LL + N+ G T
Sbjct: 63 QNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDT 122
Query: 239 PLQCAAERARASVVEIL 255
L AA V +IL
Sbjct: 123 ALHVAAALNHKKVAKIL 139
Score = 51.6 bits (118), Expect = 9e-06
Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 152 DIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+I+ L+ G + + +K NT L A++ G+ + L+ +GA V + G TALH A
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 212 AECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+ H+ LL G++ L N G T L AA S++ +L
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 106
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 506 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGLTPMHVACQHGQENIVR 554
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 555 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 614
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 615 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTAL 674
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 675 HLAARNGHLATVKLL 689
Score = 79.8 bits (188), Expect = 3e-14
Identities = 71/216 (32%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 539 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 587
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 588 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 647
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA + G TALH AA GH A V L++ A +L T L
Sbjct: 648 GHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 707
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 708 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 737
Score = 79.8 bits (188), Expect = 3e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 595 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 715 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 754
Score = 74.9 bits (176), Expect = 8e-13
Identities = 55/175 (31%), Positives = 82/175 (46%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R A + Y L + N
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARN 680
Score = 64.9 bits (151), Expect = 9e-10
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 606 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 654
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 715 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 759
Score = 59.3 bits (137), Expect = 4e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKISV 497
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILL 557
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 67/130 (51%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVER 489
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G+TP+ A + +
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQ 549
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 550 ENIVRILLRR 559
Score = 39.5 bits (88), Expect = 0.037
Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE L AR
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKISV 497
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 498 NAKDEDQWTALHFAAQNGDE 517
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 83.4 bits (197), Expect = 2e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 506 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGRTPMHVACQHGQENIVR 554
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 555 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 614
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 615 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTAL 674
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 675 HLAARNGHLATVKLL 689
Score = 79.8 bits (188), Expect = 3e-14
Identities = 71/216 (32%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 539 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 587
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 588 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 647
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA + G TALH AA GH A V L++ A +L T L
Sbjct: 648 GHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 707
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 708 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 737
Score = 79.8 bits (188), Expect = 3e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 595 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 715 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 754
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/175 (31%), Positives = 82/175 (46%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 565
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 566 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 625
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R A + Y L + N
Sbjct: 626 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARN 680
Score = 64.9 bits (151), Expect = 9e-10
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 606 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 654
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 715 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 759
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 498 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 557
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 558 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 430 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 489
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G TP+ A + +
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 550 ENIVRILLRR 559
Score = 41.5 bits (93), Expect = 0.009
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE+L AR
Sbjct: 438 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 497
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 498 NAKDEDQWTALHFAAQNGDE 517
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 63/195 (32%), Positives = 92/195 (47%), Gaps = 13/195 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L AA++G E + R+LLEK +E EG T + A G IV+
Sbjct: 554 TALHFAAQNGDESSTRLLLEK-----------NASVNEVDFEGRTPMHVACQHGQENIVR 602
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADIHKANKYNNTCLMIAAYK 181
L++ G DV+ + PL A ++G L IVK L + G ++ T L +AA +
Sbjct: 603 ILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQR 662
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPL 240
G+ V + L+D + V+ +L T LH AAE GH + LL GA K +G T L
Sbjct: 663 GHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTAL 722
Query: 241 QCAAERARASVVEIL 255
AA + V++L
Sbjct: 723 HLAARNGHLATVKLL 737
Score = 80.6 bits (190), Expect = 2e-14
Identities = 71/216 (32%), Positives = 99/216 (45%), Gaps = 19/216 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TP+ A +HG+E VRILL R V + +G D ++ L A+ GHL IVK
Sbjct: 587 TPMHVACQHGQENIVRILL---RRGVDVSLQGK---DAWL-----PLHYAAWQGHLPIVK 635
Query: 123 RLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L K G VN T TPL A G + + L+ +D++ + T L +AA
Sbjct: 636 LLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAET 695
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPL 240
G+ + LL GA + G TALH AA GH A V L++ A +L T L
Sbjct: 696 GHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTAL 755
Query: 241 QCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
AA + VVE E+ A+ I+ ++ G S
Sbjct: 756 HLAAAHGHSEVVE------ELVSADVIDLFDEQGLS 785
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/160 (31%), Positives = 73/160 (45%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V + ++G T L A+ GH + + L+ +DVN + TPL A G +
Sbjct: 643 VSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 702
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
L+ GA T L +AA G+L V+ L++ A V R TALH AA G
Sbjct: 703 LLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 762
Query: 216 HAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
H+ VV L+ L +E G++ L AA+ A VE L
Sbjct: 763 HSEVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETL 802
Score = 75.4 bits (177), Expect = 6e-13
Identities = 55/175 (31%), Positives = 82/175 (46%), Gaps = 2/175 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A+ G + + L++ A VN TP+ AC G+ +IV+ L+R G D+
Sbjct: 554 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 613
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
K L AA++G+L +V+ L G V+ + L G T LH AA+ GH V L+D
Sbjct: 614 QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILID 673
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFAN 279
+ + + + TPL AAE S +L R A + Y L + N
Sbjct: 674 LCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARN 728
Score = 64.5 bits (150), Expect = 1e-09
Identities = 54/166 (32%), Positives = 76/166 (45%), Gaps = 12/166 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G RIL++ +C + + + T L A+ GH + +
Sbjct: 654 TPLHLAAQRGHYRVARILID-----LCSDV------NVCSLLAQTPLHVAAETGHTSTAR 702
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L+ GA T T L A G L VK LV AD+ N T L +AA G
Sbjct: 703 LLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 762
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ +VV+ L+ + +D G +ALH AA+ HA V +LL HGA
Sbjct: 763 HSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 807
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/159 (28%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
GA+ L A AG K L+ A+ N + R STPL A +V+ L+ +
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ ++ T L AA G + LL+ A V++ G T +H A + G +V LL
Sbjct: 546 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILL 605
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
G + L ++ PL AA + +V++LA +P V+
Sbjct: 606 RRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 644
Score = 49.2 bits (112), Expect = 5e-05
Identities = 37/130 (28%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
DV+ A + ++ L A G+ + K+L+ + A+ + +N+ +T L +A + VV+
Sbjct: 478 DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVEL 537
Query: 190 LLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERAR 248
LL V+ + TALHFAA+ G + LL+ A + + G TP+ A + +
Sbjct: 538 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 597
Query: 249 ASVVEILAAR 258
++V IL R
Sbjct: 598 ENIVRILLRR 607
Score = 41.5 bits (93), Expect = 0.009
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVT 262
GA+ LH A E G LL + A L+N G TPL A ER VVE+L AR
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545
Query: 263 RAEAIEAYELLGASFANDKE 282
A+ + + L + N E
Sbjct: 546 NAKDEDQWTALHFAAQNGDE 565
>BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 82.2 bits (194), Expect = 5e-15
Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
Query: 115 AGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTC 174
AG LA +K+ ++G V+ TPL AC G +D+VK+L+ GA+++ + + T
Sbjct: 502 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 561
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTN 233
L A + G D+V+ L++SGA +D ++ +T L+ A E V LLD GAK L N
Sbjct: 562 LHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLEN 621
Query: 234 ENGMTPLQCAAERARASVVEIL 255
G + + A A +++++
Sbjct: 622 RKGHSAMDVAKAYADYRIIDLI 643
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/105 (39%), Positives = 58/105 (55%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A +G++ +VK L++ GA+VN + TPL AC G+ DIV+ LV GA I
Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
A+ N+T L A LD V++LLD GA+ G +A+ A
Sbjct: 587 ASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVA 631
Score = 51.2 bits (117), Expect = 1e-05
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D + CTP + AA G E ++ IL + ++ EG +G H
Sbjct: 78 DRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEG---------KGVLFYCILPTKRH 128
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGR--LDIVKYLVRHGADIHKAN-KYNNTC 174
++ GADVN++T AC + D+ + GA+ + N T
Sbjct: 129 YRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTA 188
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTN 233
LM A+ +G +++V+ +L+ G V+ A HFAA+ G ++ L + + L +
Sbjct: 189 LMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLIS 248
Query: 234 ENGMTPLQCAAERARASVVEILAAR 258
NG TPL AA A + +A R
Sbjct: 249 INGNTPLHYAAMGGFADCCKYIAQR 273
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 9/166 (5%)
Query: 125 VKAGADVNHA-TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
++ GA+ N + T T L A EG ++IV+ ++ G +++ + + AA G+
Sbjct: 171 LEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGF 230
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQC 242
D+++ L V ++ G T LH+AA G A + G + N + TP
Sbjct: 231 FDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTP--- 287
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYCLRM 288
RA A AA E+ RAE I A +L N + LR+
Sbjct: 288 ---RAVAKEGGFKAASKEIRRAERI-ANKLARPGAKNPNPLWALRL 329
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/44 (40%), Positives = 24/44 (54%)
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
+ L +A+ +D+V FLLD GA D + G T AAE GH
Sbjct: 50 SALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGH 93
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/72 (29%), Positives = 31/72 (43%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G I+K L DV + +TPL A G D KY+ + G D+ N +
Sbjct: 225 AAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDH 284
Query: 172 NTCLMIAAYKGY 183
T +A G+
Sbjct: 285 KTPRAVAKEGGF 296
Score = 31.5 bits (68), Expect = 9.9
Identities = 45/175 (25%), Positives = 70/175 (40%), Gaps = 11/175 (6%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G +AL AS + + +V L+ GA + R TP A G ++ L + A
Sbjct: 46 INGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKA 105
Query: 163 DIHKANKYNNTCLM--IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA-- 218
D+ + L I K + L+ GA V++ G A E H
Sbjct: 106 DMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKD 165
Query: 219 VVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYE 271
V + L+ GA + + G T L E +R VVEI+ R + R + A++
Sbjct: 166 VCLTFLEKGANPNAINSSTGRTALM---EASREGVVEIV--RGILERGGEVNAFD 215
>AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 82.2 bits (194), Expect = 5e-15
Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
Query: 115 AGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTC 174
AG LA +K+ ++G V+ TPL AC G +D+VK+L+ GA+++ + + T
Sbjct: 502 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 561
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTN 233
L A + G D+V+ L++SGA +D ++ +T L+ A E V LLD GAK L N
Sbjct: 562 LHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLEN 621
Query: 234 ENGMTPLQCAAERARASVVEIL 255
G + + A A +++++
Sbjct: 622 RKGHSAMDVAKAYADYRIIDLI 643
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/105 (39%), Positives = 58/105 (55%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A +G++ +VK L++ GA+VN + TPL AC G+ DIV+ LV GA I
Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
A+ N+T L A LD V++LLD GA+ G +A+ A
Sbjct: 587 ASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVA 631
Score = 51.2 bits (117), Expect = 1e-05
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D + CTP + AA G E ++ IL + ++ EG +G H
Sbjct: 78 DRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEG---------KGVLFYCILPTKRH 128
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGR--LDIVKYLVRHGADIHKAN-KYNNTC 174
++ GADVN++T AC + D+ + GA+ + N T
Sbjct: 129 YRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTA 188
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTN 233
LM A+ +G +++V+ +L+ G V+ A HFAA+ G ++ L + + L +
Sbjct: 189 LMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLIS 248
Query: 234 ENGMTPLQCAAERARASVVEILAAR 258
NG TPL AA A + +A R
Sbjct: 249 INGNTPLHYAAMGGFADCCKYIAQR 273
Score = 44.0 bits (99), Expect = 0.002
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 9/166 (5%)
Query: 125 VKAGADVNHA-TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
++ GA+ N + T T L A EG ++IV+ ++ G +++ + + AA G+
Sbjct: 171 LEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGF 230
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQC 242
D+++ L V ++ G T LH+AA G A + G + N + TP
Sbjct: 231 FDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTP--- 287
Query: 243 AAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYCLRM 288
RA A AA E+ RAE I A +L N + LR+
Sbjct: 288 ---RAVAKEGGFKAASKEIRRAERI-ANKLARPGAKNPNPLWALRL 329
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/44 (40%), Positives = 24/44 (54%)
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGH 216
+ L +A+ +D+V FLLD GA D + G T AAE GH
Sbjct: 50 SALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGH 93
Score = 33.9 bits (74), Expect = 1.8
Identities = 21/72 (29%), Positives = 31/72 (43%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G I+K L DV + +TPL A G D KY+ + G D+ N +
Sbjct: 225 AAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDH 284
Query: 172 NTCLMIAAYKGY 183
T +A G+
Sbjct: 285 KTPRAVAKEGGF 296
Score = 31.5 bits (68), Expect = 9.9
Identities = 45/175 (25%), Positives = 70/175 (40%), Gaps = 11/175 (6%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G +AL AS + + +V L+ GA + R TP A G ++ L + A
Sbjct: 46 INGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKA 105
Query: 163 DIHKANKYNNTCLM--IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA-- 218
D+ + L I K + L+ GA V++ G A E H
Sbjct: 106 DMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKD 165
Query: 219 VVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYE 271
V + L+ GA + + G T L E +R VVEI+ R + R + A++
Sbjct: 166 VCLTFLEKGANPNAINSSTGRTALM---EASREGVVEIV--RGILERGGEVNAFD 215
>AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21669 fis, clone COL08988. ).
Length = 416
Score = 82.2 bits (194), Expect = 5e-15
Identities = 46/142 (32%), Positives = 77/142 (54%), Gaps = 1/142 (0%)
Query: 115 AGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTC 174
AG LA +K+ ++G V+ TPL AC G +D+VK+L+ GA+++ + + T
Sbjct: 142 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 201
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTN 233
L A + G D+V+ L++SGA +D ++ +T L+ A E V LLD GAK L N
Sbjct: 202 LHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLEN 261
Query: 234 ENGMTPLQCAAERARASVVEIL 255
G + + A A +++++
Sbjct: 262 RKGHSAMDVAKAYADYRIIDLI 283
Score = 64.9 bits (151), Expect = 9e-10
Identities = 41/105 (39%), Positives = 58/105 (55%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A +G++ +VK L++ GA+VN + TPL AC G+ DIV+ LV GA I
Sbjct: 167 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 226
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
A+ N+T L A LD V++LLD GA+ G +A+ A
Sbjct: 227 ASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVA 271
>BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 27
(VPS9 domain) protein.
Length = 1050
Score = 81.8 bits (193), Expect = 7e-15
Identities = 51/138 (36%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 122 KRLVK---AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
KRL K +G VN ++ S+PL A GR D++ L++HGA+ N L +A
Sbjct: 725 KRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLA 784
Query: 179 AYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGM 237
+G+ VV+ LLDS A+ + + L G T L +A GH +V LL HGA + +N G
Sbjct: 785 CQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGN 844
Query: 238 TPLQCAAERARASVVEIL 255
T L A VVE+L
Sbjct: 845 TALHEAVIEKHVFVVELL 862
Score = 72.1 bits (169), Expect = 6e-12
Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G++ L A+ G ++ L+K GA+ + PL AC +G +VK L+ A
Sbjct: 743 DGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAK 802
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+K + NT L+ A G+ ++V LL GA ++ G TALH A H VV L
Sbjct: 803 PNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELL 862
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILAARP 259
L HGA + + N+ T + CA + ++ ++E+L P
Sbjct: 863 LLHGASVQVLNKRQRTAVDCAEQNSK--IMELLQVVP 897
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/153 (32%), Positives = 72/153 (47%), Gaps = 4/153 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G +++ LV GA VN +TPL AC +G + L+ + A
Sbjct: 463 GHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASA 522
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL---DSGARVDDRALCGATALHFAAECGHAAVVC 221
+ NT L +A G+ D V+ L+ R+D G T LH AA G+ V+
Sbjct: 523 EVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIE 582
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
+LL +GA + N TPL+CA SV+E
Sbjct: 583 TLLQNGASTEIQNRLKETPLKCALNSKILSVME 615
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/148 (33%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 51 LNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
L ++V S DG +PL AA HGR + +LL+ G D+ A L
Sbjct: 735 LGVNVTSQDG--SSPLHVAALHGRADLIPLLLKHG------ANAGARNADQ-----AVPL 781
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH +VK L+ + A N + +TPL AC G ++V L++HGA I+ +N
Sbjct: 782 HLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNN 841
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARV 197
NT L A + ++ VV+ LL GA V
Sbjct: 842 KGNTALHEAVIEKHVFVVELLLLHGASV 869
Score = 56.0 bits (129), Expect = 4e-07
Identities = 39/120 (32%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL A G+ ++ LV GA ++ + + T L +A KGY V LL A +
Sbjct: 465 TPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEV 524
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM----LTNENGMTPLQCAAERARASVVEIL 255
+ G T LH A GH V +L+ + + + NE G TPL AA V+E L
Sbjct: 525 QDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETL 584
>AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein
protein.
Length = 407
Score = 81.8 bits (193), Expect = 7e-15
Identities = 51/138 (36%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 122 KRLVK---AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
KRL K +G VN ++ S+PL A GR D++ L++HGA+ N L +A
Sbjct: 82 KRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLA 141
Query: 179 AYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGM 237
+G+ VV+ LLDS A+ + + L G T L +A GH +V LL HGA + +N G
Sbjct: 142 CQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGN 201
Query: 238 TPLQCAAERARASVVEIL 255
T L A VVE+L
Sbjct: 202 TALHEAVIEKHVFVVELL 219
Score = 72.1 bits (169), Expect = 6e-12
Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G++ L A+ G ++ L+K GA+ + PL AC +G +VK L+ A
Sbjct: 100 DGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAK 159
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+K + NT L+ A G+ ++V LL GA ++ G TALH A H VV L
Sbjct: 160 PNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELL 219
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILAARP 259
L HGA + + N+ T + CA + ++ ++E+L P
Sbjct: 220 LLHGASVQVLNKRQRTAVDCAEQNSK--IMELLQVVP 254
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/148 (33%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 51 LNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
L ++V S DG +PL AA HGR + +LL+ G D+ A L
Sbjct: 92 LGVNVTSQDG--SSPLHVAALHGRADLIPLLLKHG------ANAGARNADQ-----AVPL 138
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH +VK L+ + A N + +TPL AC G ++V L++HGA I+ +N
Sbjct: 139 HLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNN 198
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARV 197
NT L A + ++ VV+ LL GA V
Sbjct: 199 KGNTALHEAVIEKHVFVVELLLLHGASV 226
>AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein.
Length = 1060
Score = 81.8 bits (193), Expect = 7e-15
Identities = 51/138 (36%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 122 KRLVK---AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
KRL K +G VN ++ S+PL A GR D++ L++HGA+ N L +A
Sbjct: 735 KRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLA 794
Query: 179 AYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGM 237
+G+ VV+ LLDS A+ + + L G T L +A GH +V LL HGA + +N G
Sbjct: 795 CQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGN 854
Query: 238 TPLQCAAERARASVVEIL 255
T L A VVE+L
Sbjct: 855 TALHEAVIEKHVFVVELL 872
Score = 72.1 bits (169), Expect = 6e-12
Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G++ L A+ G ++ L+K GA+ + PL AC +G +VK L+ A
Sbjct: 753 DGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAK 812
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+K + NT L+ A G+ ++V LL GA ++ G TALH A H VV L
Sbjct: 813 PNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELL 872
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEILAARP 259
L HGA + + N+ T + CA + ++ ++E+L P
Sbjct: 873 LLHGASVQVLNKRQRTAVDCAEQNSK--IMELLQVVP 907
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/153 (32%), Positives = 72/153 (47%), Gaps = 4/153 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ G +++ LV GA VN +TPL AC +G + L+ + A
Sbjct: 473 GHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASA 532
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL---DSGARVDDRALCGATALHFAAECGHAAVVC 221
+ NT L +A G+ D V+ L+ R+D G T LH AA G+ V+
Sbjct: 533 EVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIE 592
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVE 253
+LL +GA + N TPL+CA SV+E
Sbjct: 593 TLLQNGASTEIQNRLKETPLKCALNSKILSVME 625
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/148 (33%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 51 LNIDVCS-DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
L ++V S DG +PL AA HGR + +LL+ G D+ A L
Sbjct: 745 LGVNVTSQDG--SSPLHVAALHGRADLIPLLLKHG------ANAGARNADQ-----AVPL 791
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH +VK L+ + A N + +TPL AC G ++V L++HGA I+ +N
Sbjct: 792 HLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNN 851
Query: 170 YNNTCLMIAAYKGYLDVVQFLLDSGARV 197
NT L A + ++ VV+ LL GA V
Sbjct: 852 KGNTALHEAVIEKHVFVVELLLLHGASV 879
Score = 56.0 bits (129), Expect = 4e-07
Identities = 39/120 (32%), Positives = 55/120 (45%), Gaps = 4/120 (3%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL A G+ ++ LV GA ++ + + T L +A KGY V LL A +
Sbjct: 475 TPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEV 534
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM----LTNENGMTPLQCAAERARASVVEIL 255
+ G T LH A GH V +L+ + + + NE G TPL AA V+E L
Sbjct: 535 QDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETL 594
>BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS
box-containing 2 protein.
Length = 587
Score = 81.4 bits (192), Expect = 9e-15
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 13/197 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA +G+ G +++L + GT+ D+ ++ TA++ A+ GHL +
Sbjct: 93 PLHEAAYYGQVGCLKVLQRAY--------PGTI--DQRTLQEETAVYLATCRGHLDCLLS 142
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI-HKANKYNNTCLMIAAYKG 182
L++AGA+ + + ++ TPL AC + VK LV+H AD H+ N+ T L + +
Sbjct: 143 LLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNR-GWTALHESVSRN 201
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQ 241
L+V+Q L+ GA+V+ + G T L AA+ G + L +GA + T + + L
Sbjct: 202 DLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALY 261
Query: 242 CAAERARASVVEILAAR 258
A + VVE L ++
Sbjct: 262 EACKNEHEEVVEFLLSQ 278
Score = 79.8 bits (188), Expect = 3e-14
Identities = 52/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L+ A + VK LV+ AD NH T L + L++++ LV GA +
Sbjct: 159 TPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVES 218
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
N Y T L +AA G L+ ++FL GA ++ +A A+AL+ A + H VV LL
Sbjct: 219 KNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQ 278
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTR 263
GA TN++G+ PL A+++ +V++L TR
Sbjct: 279 GADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR 316
Score = 78.6 bits (185), Expect = 7e-14
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 1/169 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL + L +++ LV GA V TPL A G+L+ +++L ++GADI
Sbjct: 190 GWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADI 249
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N + L A + +VV+FLL GA + G LH A++ G+ +V LL
Sbjct: 250 NTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Query: 225 DHGAKMLTNENGMTPLQCAAERARASVVE-ILAARPEVTRAEAIEAYEL 272
++ +G++PL AAER V+E +L+AR +V A E L
Sbjct: 310 PVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARL 358
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/155 (36%), Positives = 78/155 (50%), Gaps = 9/155 (5%)
Query: 94 GTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDI 153
G K + G T L+ A+ +G L ++ L K GAD+N ++ L AC ++
Sbjct: 212 GGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEV 271
Query: 154 VKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
V++L+ GAD +K NK L IA+ KG +VQ LL +R R G + LH AAE
Sbjct: 272 VEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRR-SGVSPLHLAAE 330
Query: 214 CGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERAR 248
H V+ +LL A+ N TPL A ERAR
Sbjct: 331 RNHDEVLEALL--SARFDVN----TPL--APERAR 357
>AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 81.4 bits (192), Expect = 9e-15
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 13/197 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA +G+ G +++L + GT+ D+ ++ TA++ A+ GHL +
Sbjct: 93 PLHEAAYYGQVGCLKVLQRAY--------PGTI--DQRTLQEETAVYLATCRGHLDCLLS 142
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI-HKANKYNNTCLMIAAYKG 182
L++AGA+ + + ++ TPL AC + VK LV+H AD H+ N+ T L + +
Sbjct: 143 LLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNR-GWTALHESVSRN 201
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQ 241
L+V+Q L+ GA+V+ + G T L AA+ G + L +GA + T + + L
Sbjct: 202 DLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALY 261
Query: 242 CAAERARASVVEILAAR 258
A + VVE L ++
Sbjct: 262 EACKNEHEEVVEFLLSQ 278
Score = 79.8 bits (188), Expect = 3e-14
Identities = 52/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L+ A + VK LV+ AD NH T L + L++++ LV GA +
Sbjct: 159 TPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVES 218
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
N Y T L +AA G L+ ++FL GA ++ +A A+AL+ A + H VV LL
Sbjct: 219 KNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQ 278
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTR 263
GA TN++G+ PL A+++ +V++L TR
Sbjct: 279 GADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR 316
Score = 78.6 bits (185), Expect = 7e-14
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 1/169 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL + L +++ LV GA V TPL A G+L+ +++L ++GADI
Sbjct: 190 GWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADI 249
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N + L A + +VV+FLL GA + G LH A++ G+ +V LL
Sbjct: 250 NTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Query: 225 DHGAKMLTNENGMTPLQCAAERARASVVE-ILAARPEVTRAEAIEAYEL 272
++ +G++PL AAER V+E +L+AR +V A E L
Sbjct: 310 PVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARL 358
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/155 (36%), Positives = 78/155 (50%), Gaps = 9/155 (5%)
Query: 94 GTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDI 153
G K + G T L+ A+ +G L ++ L K GAD+N ++ L AC ++
Sbjct: 212 GGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEV 271
Query: 154 VKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
V++L+ GAD +K NK L IA+ KG +VQ LL +R R G + LH AAE
Sbjct: 272 VEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRR-SGVSPLHLAAE 330
Query: 214 CGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERAR 248
H V+ +LL A+ N TPL A ERAR
Sbjct: 331 RNHDEVLEALL--SARFDVN----TPL--APERAR 357
>AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteining
protein with a SOCS box-2 protein.
Length = 587
Score = 81.4 bits (192), Expect = 9e-15
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 13/197 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA +G+ G +++L + GT+ D+ ++ TA++ A+ GHL +
Sbjct: 93 PLHEAAYYGQVGCLKVLQRAY--------PGTI--DQRTLQEETAVYLATCRGHLDCLLS 142
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI-HKANKYNNTCLMIAAYKG 182
L++AGA+ + + ++ TPL AC + VK LV+H AD H+ N+ T L + +
Sbjct: 143 LLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNR-GWTALHESVSRN 201
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQ 241
L+V+Q L+ GA+V+ + G T L AA+ G + L +GA + T + + L
Sbjct: 202 DLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALY 261
Query: 242 CAAERARASVVEILAAR 258
A + VVE L ++
Sbjct: 262 EACKNEHEEVVEFLLSQ 278
Score = 79.8 bits (188), Expect = 3e-14
Identities = 52/158 (32%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L+ A + VK LV+ AD NH T L + L++++ LV GA +
Sbjct: 159 TPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVES 218
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
N Y T L +AA G L+ ++FL GA ++ +A A+AL+ A + H VV LL
Sbjct: 219 KNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQ 278
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTR 263
GA TN++G+ PL A+++ +V++L TR
Sbjct: 279 GADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTR 316
Score = 78.6 bits (185), Expect = 7e-14
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 1/169 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL + L +++ LV GA V TPL A G+L+ +++L ++GADI
Sbjct: 190 GWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADI 249
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N + L A + +VV+FLL GA + G LH A++ G+ +V LL
Sbjct: 250 NTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 309
Query: 225 DHGAKMLTNENGMTPLQCAAERARASVVE-ILAARPEVTRAEAIEAYEL 272
++ +G++PL AAER V+E +L+AR +V A E L
Sbjct: 310 PVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARL 358
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/155 (36%), Positives = 78/155 (50%), Gaps = 9/155 (5%)
Query: 94 GTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDI 153
G K + G T L+ A+ +G L ++ L K GAD+N ++ L AC ++
Sbjct: 212 GGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEV 271
Query: 154 VKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
V++L+ GAD +K NK L IA+ KG +VQ LL +R R G + LH AAE
Sbjct: 272 VEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRR-SGVSPLHLAAE 330
Query: 214 CGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERAR 248
H V+ +LL A+ N TPL A ERAR
Sbjct: 331 RNHDEVLEALL--SARFDVN----TPL--APERAR 357
>AL158217-11|CAI22163.1| 854|Homo sapiens espin protein.
Length = 854
Score = 81.0 bits (191), Expect = 1e-14
Identities = 55/154 (35%), Positives = 81/154 (52%), Gaps = 3/154 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGAD-VNHATRTVSTPLRAACFEGRLDIVKYLVRH-GA 162
GA + A+ G ++ LV+ + VN T+ +TPL AC EG L++ +YLV+ GA
Sbjct: 138 GALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGA 197
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLD-SGARVDDRALCGATALHFAAECGHAAVVC 221
D H T L AA G+ V+ +L+ + + ++ GATA+HFAA GH V+
Sbjct: 198 DPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLS 257
Query: 222 SLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL HG ++ + G TPL AAE +IL
Sbjct: 258 WLLLHGGEISADLWGGTPLHDAAENGELECCQIL 291
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/213 (28%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D + P+ AAR G+ +R L+E+ P GAT AS GH
Sbjct: 33 DPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARN----------GATPAHDASATGH 82
Query: 118 LAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA-DIHKANKYNNTCL 175
LA ++ L+ + G V + +T L A G ++V +L+ HG D A +
Sbjct: 83 LACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPI 142
Query: 176 MIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTN 233
AA KG ++ L++ V+ + GAT L+ A + GH V L+ GA
Sbjct: 143 HYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHAR 202
Query: 234 -ENGMTPLQCAAERARASVVEILAARPEVTRAE 265
+GMTPL AA+ + V+ L + +V+ +E
Sbjct: 203 AHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSE 235
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 14/178 (7%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
P+ AA G ++R+L+E + V +T+ GAT L+ A GHL + +
Sbjct: 141 PIHYAAAKGDFPSLRLLVEHYPEGVNAQTKN----------GATPLYLACQEGHLEVTQY 190
Query: 124 LVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVR-HGADIHKANKYNNTCLMIAAYK 181
LV+ GAD + TPL AA G ++ +LV + + +K T + AA +
Sbjct: 191 LVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASR 250
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+ V+ +LL G + L G T LH AAE G L+ +GA++ + + +G T
Sbjct: 251 GHTKVLSWLLLHGGEIS-ADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Score = 54.0 bits (124), Expect = 2e-06
Identities = 50/161 (31%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTV--STPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G L +++ L AG + + R + P+ A G+L +++LV A A
Sbjct: 9 AARQGELDVLRSLHAAGL-LGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARA 67
Query: 170 YNN-TCLMIAAYKGYLDVVQFLLDSGA-RVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N T A+ G+L +Q+LL G RV D+ GAT LH AA GH VV LL HG
Sbjct: 68 RNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHG 127
Query: 228 A--KMLTNENGMTPLQCAAERARASVVEILAAR-PEVTRAE 265
+ G P+ AA + + +L PE A+
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQ 168
Score = 48.0 bits (109), Expect = 1e-04
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ GH ++ LV ++ + +T + A G ++ +L+ HG
Sbjct: 205 DGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGG 264
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+I A+ + T L AA G L+ Q L+ +GA +D R G TA + GH+
Sbjct: 265 EI-SADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHS 318
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V E +GATA+ A+ GH ++ L+ G +++ A TPL A G L+ +
Sbjct: 231 VSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEIS-ADLWGGTPLHDAAENGELECCQ 289
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFL 190
LV +GA++ ++ T ++ + G+ ++L
Sbjct: 290 ILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
>AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein
protein.
Length = 671
Score = 81.0 bits (191), Expect = 1e-14
Identities = 64/215 (29%), Positives = 96/215 (44%), Gaps = 5/215 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGAD-VNHATRTVSTPLRAACFEGRLDIVKYLVRH-GA 162
GA + A+ G ++ LV+ + VN T+ +TPL AC EG L++ +YLV+ GA
Sbjct: 40 GALPIHYAAAKGDFPSLRLLVRHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGA 99
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLD-SGARVDDRALCGATALHFAAECGHAAVVC 221
D H T L AA G+ V+ +L+ + + ++ GATA HFAA GH+ V+
Sbjct: 100 DPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLS 159
Query: 222 SLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDK 281
LL HG ++ + G T L AAE +IL + Y S N
Sbjct: 160 WLLLHGGEISADLWGGTALYDAAENGELECCQILVVNGAELEVRDRDGYAAADLSDFNGH 219
Query: 282 EY--YCLRMAYQYLHRAMAMRYDPRYGEMLKRPST 314
+ +CLR + DP K+P +
Sbjct: 220 SHCTHCLRTVENLSMEHCVLSRDPSVELEAKQPDS 254
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/156 (31%), Positives = 77/156 (49%), Gaps = 5/156 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L + GH +V L+ G D AT + P+ A +G ++ LVRH +
Sbjct: 6 GPTVLHLTARFGHPKVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVRHYPE 65
Query: 164 -IHKANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVC 221
++ K T L +A +G+L+V Q+L+ + GA RA G T LH AA+ GH+ V+
Sbjct: 66 GVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIV 125
Query: 222 SLLDHGAKMLT--NENGMTPLQCAAERARASVVEIL 255
L+ L+ +++G T AA R + V+ L
Sbjct: 126 WLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL 161
Score = 32.3 bits (70), Expect = 5.6
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V E +GATA A+ GH ++ L+ G +++ A T L A G L+ +
Sbjct: 133 VSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-ADLWGGTALYDAAENGELECCQ 191
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGY 183
LV +GA++ ++ ++ + G+
Sbjct: 192 ILVVNGAELEVRDRDGYAAADLSDFNGH 219
Score = 31.5 bits (68), Expect = 9.9
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILA 256
D+ G T LH A GH VV LL HG + G P+ AA + + +L
Sbjct: 1 DKDNSGPTVLHLTARFGHPKVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLV 60
Query: 257 AR-PEVTRAE 265
PE A+
Sbjct: 61 RHYPEGVNAQ 70
>AL031848-3|CAI19773.1| 854|Homo sapiens espin protein.
Length = 854
Score = 81.0 bits (191), Expect = 1e-14
Identities = 55/154 (35%), Positives = 81/154 (52%), Gaps = 3/154 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGAD-VNHATRTVSTPLRAACFEGRLDIVKYLVRH-GA 162
GA + A+ G ++ LV+ + VN T+ +TPL AC EG L++ +YLV+ GA
Sbjct: 138 GALPIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGA 197
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLD-SGARVDDRALCGATALHFAAECGHAAVVC 221
D H T L AA G+ V+ +L+ + + ++ GATA+HFAA GH V+
Sbjct: 198 DPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLS 257
Query: 222 SLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL HG ++ + G TPL AAE +IL
Sbjct: 258 WLLLHGGEISADLWGGTPLHDAAENGELECCQIL 291
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/213 (28%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D + P+ AAR G+ +R L+E+ P GAT AS GH
Sbjct: 33 DPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARN----------GATPAHDASATGH 82
Query: 118 LAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA-DIHKANKYNNTCL 175
LA ++ L+ + G V + +T L A G ++V +L+ HG D A +
Sbjct: 83 LACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPI 142
Query: 176 MIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTN 233
AA KG ++ L++ V+ + GAT L+ A + GH V L+ GA
Sbjct: 143 HYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHAR 202
Query: 234 -ENGMTPLQCAAERARASVVEILAARPEVTRAE 265
+GMTPL AA+ + V+ L + +V+ +E
Sbjct: 203 AHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSE 235
Score = 59.7 bits (138), Expect = 3e-08
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 14/178 (7%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
P+ AA G ++R+L+E + V +T+ GAT L+ A GHL + +
Sbjct: 141 PIHYAAAKGDFPSLRLLVEHYPEGVNAQTKN----------GATPLYLACQEGHLEVTQY 190
Query: 124 LVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVR-HGADIHKANKYNNTCLMIAAYK 181
LV+ GAD + TPL AA G ++ +LV + + +K T + AA +
Sbjct: 191 LVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASR 250
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+ V+ +LL G + L G T LH AAE G L+ +GA++ + + +G T
Sbjct: 251 GHTKVLSWLLLHGGEIS-ADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Score = 54.0 bits (124), Expect = 2e-06
Identities = 50/161 (31%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTV--STPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A+ G L +++ L AG + + R + P+ A G+L +++LV A A
Sbjct: 9 AARQGELDVLRSLHAAGL-LGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARA 67
Query: 170 YNN-TCLMIAAYKGYLDVVQFLLDSGA-RVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N T A+ G+L +Q+LL G RV D+ GAT LH AA GH VV LL HG
Sbjct: 68 RNGATPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHG 127
Query: 228 A--KMLTNENGMTPLQCAAERARASVVEILAAR-PEVTRAE 265
+ G P+ AA + + +L PE A+
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEHYPEGVNAQ 168
Score = 48.0 bits (109), Expect = 1e-04
Identities = 33/115 (28%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G T L A+ GH ++ LV ++ + +T + A G ++ +L+ HG
Sbjct: 205 DGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGG 264
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+I A+ + T L AA G L+ Q L+ +GA +D R G TA + GH+
Sbjct: 265 EI-SADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYTAADLSDFNGHS 318
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V E +GATA+ A+ GH ++ L+ G +++ A TPL A G L+ +
Sbjct: 231 VSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEIS-ADLWGGTPLHDAAENGELECCQ 289
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFL 190
LV +GA++ ++ T ++ + G+ ++L
Sbjct: 290 ILVVNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324
>AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein.
Length = 671
Score = 81.0 bits (191), Expect = 1e-14
Identities = 64/215 (29%), Positives = 96/215 (44%), Gaps = 5/215 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGAD-VNHATRTVSTPLRAACFEGRLDIVKYLVRH-GA 162
GA + A+ G ++ LV+ + VN T+ +TPL AC EG L++ +YLV+ GA
Sbjct: 40 GALPIHYAAAKGDFPSLRLLVRHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGA 99
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLD-SGARVDDRALCGATALHFAAECGHAAVVC 221
D H T L AA G+ V+ +L+ + + ++ GATA HFAA GH+ V+
Sbjct: 100 DPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLS 159
Query: 222 SLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDK 281
LL HG ++ + G T L AAE +IL + Y S N
Sbjct: 160 WLLLHGGEISADLWGGTALYDAAENGELECCQILVVNGAELEVRDRDGYAAADLSDFNGH 219
Query: 282 EY--YCLRMAYQYLHRAMAMRYDPRYGEMLKRPST 314
+ +CLR + DP K+P +
Sbjct: 220 SHCTHCLRTVENLSMEHCVLSRDPSVELEAKQPDS 254
Score = 64.1 bits (149), Expect = 2e-09
Identities = 49/156 (31%), Positives = 77/156 (49%), Gaps = 5/156 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L + GH +V L+ G D AT + P+ A +G ++ LVRH +
Sbjct: 6 GPTVLHLTARFGHPKVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLVRHYPE 65
Query: 164 -IHKANKYNNTCLMIAAYKGYLDVVQFLL-DSGARVDDRALCGATALHFAAECGHAAVVC 221
++ K T L +A +G+L+V Q+L+ + GA RA G T LH AA+ GH+ V+
Sbjct: 66 GVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIV 125
Query: 222 SLLDHGAKMLT--NENGMTPLQCAAERARASVVEIL 255
L+ L+ +++G T AA R + V+ L
Sbjct: 126 WLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL 161
Score = 32.3 bits (70), Expect = 5.6
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Query: 96 VKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVK 155
V E +GATA A+ GH ++ L+ G +++ A T L A G L+ +
Sbjct: 133 VSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-ADLWGGTALYDAAENGELECCQ 191
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGY 183
LV +GA++ ++ ++ + G+
Sbjct: 192 ILVVNGAELEVRDRDGYAAADLSDFNGH 219
Score = 31.5 bits (68), Expect = 9.9
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 199 DRALCGATALHFAAECGHAAVVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILA 256
D+ G T LH A GH VV LL HG + G P+ AA + + +L
Sbjct: 1 DKDNSGPTVLHLTARFGHPKVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLLV 60
Query: 257 AR-PEVTRAE 265
PE A+
Sbjct: 61 RHYPEGVNAQ 70
>AK123496-1|BAC85629.1| 656|Homo sapiens protein ( Homo sapiens
cDNA FLJ41502 fis, clone BRTHA2007122, weakly similar
to ANKYRIN 2. ).
Length = 656
Score = 80.6 bits (190), Expect = 2e-14
Identities = 59/177 (33%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS GH IV L++AG VN T TPL A G I +L++ GA++
Sbjct: 69 GWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQGAEL 128
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR-ALCGATALHFAAECGHAAVVCSL 223
+ T L G+ +V+FLLDSGA + R +CG T L AA GH +V
Sbjct: 129 EMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYF 188
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL-AARPEVTRA--EAIEAYELLGAS 276
L+HG K+ + +G T A + +V ++ P + ++ + E YE L +S
Sbjct: 189 LNHGVKVDARDHSGATARMLAKQYGHMKIVALMDTYSPSLPKSLYRSPEKYEDLSSS 245
Score = 62.5 bits (145), Expect = 5e-09
Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 109 LWCASGAGHLAIVKRLV-KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A+ G +VK V + D+N TPL A + G IV L+ G ++
Sbjct: 39 LHTAASIGQYEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVP 98
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
T LM+A+ G + FLL GA ++ + + G TAL GH +V LLD G
Sbjct: 99 TPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSG 158
Query: 228 AKMLTNEN--GMTPLQCAAERARASVVE 253
A E G TPL AA +V+
Sbjct: 159 ANANVREPICGFTPLMEAAAAGHEIIVQ 186
Score = 55.6 bits (128), Expect = 5e-07
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 13/164 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A+ G + V +LLE V + EG T L AS G+ +I
Sbjct: 71 TPLMYASYIGHDTIVHLLLE-----------AGVSVNVPTPEGQTPLMLASSCGNESIAY 119
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY-NNTCLMIAAYK 181
L++ GA++ T L G +V++L+ GA+ + T LM AA
Sbjct: 120 FLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAA 179
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
G+ +VQ+ L+ G +VD R GATA A + GH +V +L+D
Sbjct: 180 GHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIV-ALMD 222
>AB075857-1|BAB85563.1| 606|Homo sapiens KIAA1977 protein protein.
Length = 606
Score = 80.6 bits (190), Expect = 2e-14
Identities = 59/177 (33%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L AS GH IV L++AG VN T TPL A G I +L++ GA++
Sbjct: 19 GWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQGAEL 78
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR-ALCGATALHFAAECGHAAVVCSL 223
+ T L G+ +V+FLLDSGA + R +CG T L AA GH +V
Sbjct: 79 EMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYF 138
Query: 224 LDHGAKM-LTNENGMTPLQCAAERARASVVEIL-AARPEVTRA--EAIEAYELLGAS 276
L+HG K+ + +G T A + +V ++ P + ++ + E YE L +S
Sbjct: 139 LNHGVKVDARDHSGATARMLAKQYGHMKIVALMDTYSPSLPKSLYRSPEKYEDLSSS 195
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/135 (31%), Positives = 60/135 (44%), Gaps = 2/135 (1%)
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
+ RL + D+N TPL A + G IV L+ G ++ T LM+A+
Sbjct: 2 ILRLFRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASS 61
Query: 181 KGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN--GMT 238
G + FLL GA ++ + + G TAL GH +V LLD GA E G T
Sbjct: 62 CGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFT 121
Query: 239 PLQCAAERARASVVE 253
PL AA +V+
Sbjct: 122 PLMEAAAAGHEIIVQ 136
Score = 55.6 bits (128), Expect = 5e-07
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 13/164 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL+ A+ G + V +LLE V + EG T L AS G+ +I
Sbjct: 21 TPLMYASYIGHDTIVHLLLE-----------AGVSVNVPTPEGQTPLMLASSCGNESIAY 69
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY-NNTCLMIAAYK 181
L++ GA++ T L G +V++L+ GA+ + T LM AA
Sbjct: 70 FLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAA 129
Query: 182 GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
G+ +VQ+ L+ G +VD R GATA A + GH +V +L+D
Sbjct: 130 GHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIV-ALMD 172
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 80.6 bits (190), Expect = 2e-14
Identities = 53/158 (33%), Positives = 74/158 (46%), Gaps = 1/158 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K LVKAGA+V + +T L AC + L+ G+
Sbjct: 108 DGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 167
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 168 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 227
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPE 260
L+ GA + N G TPL+ A V +L P+
Sbjct: 228 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ 265
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/152 (32%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GHL +V+ L+KAG D++ T L A G +I+ L+ G +
Sbjct: 43 GRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCAL 102
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +K NT L A++ G+ + L+ +GA V + G TALH A + H+ LL
Sbjct: 103 DRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLL 162
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G++ L N G T L AA S++ +L
Sbjct: 163 LAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 194
Score = 68.5 bits (160), Expect = 7e-11
Identities = 67/230 (29%), Positives = 104/230 (45%), Gaps = 18/230 (7%)
Query: 31 MSLTLYALLYEKKTDEIDDLLN----IDVCSDGVKCTPLITAARHGREGAVRILLEKFRP 86
+S L Y+ +T+ + L+N + V G TPL AA G V+ILL K
Sbjct: 11 LSERLLVAAYKGQTENVVQLINKGARVAVTKHGR--TPLHLAANKGHLPVVQILL-KAGC 67
Query: 87 PVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC 146
+ ++ +G D+ TAL A+ G+ I+ L+ G ++ + +T L A
Sbjct: 68 DLDVQDDG----DQ------TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEAS 117
Query: 147 FEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGAT 206
+ G K LV+ GA++ NK NT L +A + + LL +G+R D + G T
Sbjct: 118 WHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT 177
Query: 207 ALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH AA H +++ LL + N+ G T L AA V +IL
Sbjct: 178 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 227
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 1/158 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K L+KAGA+V + +T L AC + L+ G+
Sbjct: 107 DGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 166
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 167 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPE 260
L+ GA + N G TPL+ A V +L P+
Sbjct: 227 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ 264
Score = 77.4 bits (182), Expect = 2e-13
Identities = 49/152 (32%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GHL +V+ L+KAG D++ T L A G +I+ L+ G +
Sbjct: 42 GRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCAL 101
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +K NT L A++ G+ + L+ +GA V + G TALH A + H+ LL
Sbjct: 102 DRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLL 161
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G++ L N G T L AA S++ +L
Sbjct: 162 LAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 193
Score = 68.1 bits (159), Expect = 9e-11
Identities = 66/230 (28%), Positives = 104/230 (45%), Gaps = 18/230 (7%)
Query: 31 MSLTLYALLYEKKTDEIDDLLN----IDVCSDGVKCTPLITAARHGREGAVRILLEKFRP 86
+S L Y+ +T+ + L+N + V G TPL AA G V+ILL K
Sbjct: 10 LSERLLVAAYKGQTENVVQLINKGARVAVTKHGR--TPLHLAANKGHLPVVQILL-KAGC 66
Query: 87 PVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC 146
+ ++ +G D+ TAL A+ G+ I+ L+ G ++ + +T L A
Sbjct: 67 DLDVQDDG----DQ------TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEAS 116
Query: 147 FEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGAT 206
+ G K L++ GA++ NK NT L +A + + LL +G+R D + G T
Sbjct: 117 WHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT 176
Query: 207 ALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH AA H +++ LL + N+ G T L AA V +IL
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 80.2 bits (189), Expect = 2e-14
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 1/158 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS G K L+KAGA+V + +T L AC + L+ G+
Sbjct: 107 DGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSR 166
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
N +TCL +AA +L +++ LL + V ++ G TALH AA H V L
Sbjct: 167 ADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
Query: 224 LDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPE 260
L+ GA + N G TPL+ A V +L P+
Sbjct: 227 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ 264
Score = 77.4 bits (182), Expect = 2e-13
Identities = 49/152 (32%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GHL +V+ L+KAG D++ T L A G +I+ L+ G +
Sbjct: 42 GRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCAL 101
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ +K NT L A++ G+ + L+ +GA V + G TALH A + H+ LL
Sbjct: 102 DRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLL 161
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G++ L N G T L AA S++ +L
Sbjct: 162 LAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 193
Score = 68.1 bits (159), Expect = 9e-11
Identities = 66/230 (28%), Positives = 104/230 (45%), Gaps = 18/230 (7%)
Query: 31 MSLTLYALLYEKKTDEIDDLLN----IDVCSDGVKCTPLITAARHGREGAVRILLEKFRP 86
+S L Y+ +T+ + L+N + V G TPL AA G V+ILL K
Sbjct: 10 LSERLLVAAYKGQTENVVQLINKGARVAVTKHGR--TPLHLAANKGHLPVVQILL-KAGC 66
Query: 87 PVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC 146
+ ++ +G D+ TAL A+ G+ I+ L+ G ++ + +T L A
Sbjct: 67 DLDVQDDG----DQ------TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEAS 116
Query: 147 FEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGAT 206
+ G K L++ GA++ NK NT L +A + + LL +G+R D + G T
Sbjct: 117 WHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT 176
Query: 207 ALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH AA H +++ LL + N+ G T L AA V +IL
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 79.8 bits (188), Expect = 3e-14
Identities = 58/180 (32%), Positives = 85/180 (47%), Gaps = 4/180 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA+ AS GH+ I+K L+K DV + + A F +++ L R AD+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L IA KG+L VV+ LLD G + G T LH A ++ LL
Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLL 583
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA---RPEVTRAEAIEAYELLGASFAND 280
+ GA + +TN NG L AA R S + +L + RP + + + Y L + N+
Sbjct: 584 EAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Score = 52.8 bits (121), Expect = 4e-06
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 18/217 (8%)
Query: 46 EIDDLL---NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
+++DLL ++DV T + A+++G +++LL++ V +E E
Sbjct: 446 KVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQ---NVDVEAEDK------- 495
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G A+ A+ A+++ L + AD+N + TPL A +G L +VK L+ G
Sbjct: 496 -DGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGC 554
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ +T L A K D++ LL++GA V G ALH AA G+ + +
Sbjct: 555 HPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRV 614
Query: 223 LLDHGAK-MLTNE---NGMTPLQCAAERARASVVEIL 255
LL + + +E +G T L AA V E+L
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 9/170 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-- 161
EG T L A I+ L++AGADV L A G ++ L+
Sbjct: 562 EGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPR 621
Query: 162 ---ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHA 217
D K + Y T L +AA +++V + L+ G A +D + + TALH A E H
Sbjct: 622 PWIVDEKKDDGY--TALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHT 679
Query: 218 AVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+V L+ GAK+ + +++G TPL A S + L +V + +A
Sbjct: 680 QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDA 729
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 79.8 bits (188), Expect = 3e-14
Identities = 58/180 (32%), Positives = 85/180 (47%), Gaps = 4/180 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA+ AS GH+ I+K L+K DV + + A F +++ L R AD+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L IA KG+L VV+ LLD G + G T LH A ++ LL
Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLL 583
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA---RPEVTRAEAIEAYELLGASFAND 280
+ GA + +TN NG L AA R S + +L + RP + + + Y L + N+
Sbjct: 584 EAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Score = 52.8 bits (121), Expect = 4e-06
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 18/217 (8%)
Query: 46 EIDDLL---NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
+++DLL ++DV T + A+++G +++LL++ V +E E
Sbjct: 446 KVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQ---NVDVEAEDK------- 495
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G A+ A+ A+++ L + AD+N + TPL A +G L +VK L+ G
Sbjct: 496 -DGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGC 554
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ +T L A K D++ LL++GA V G ALH AA G+ + +
Sbjct: 555 HPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRV 614
Query: 223 LLDHGAK-MLTNE---NGMTPLQCAAERARASVVEIL 255
LL + + +E +G T L AA V E+L
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 9/170 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-- 161
EG T L A I+ L++AGADV L A G ++ L+
Sbjct: 562 EGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPR 621
Query: 162 ---ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHA 217
D K + Y T L +AA +++V + L+ G A +D + + TALH A E H
Sbjct: 622 PWIVDEKKDDGY--TALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHT 679
Query: 218 AVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+V L+ GAK+ + +++G TPL A S + L +V + +A
Sbjct: 680 QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDA 729
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 79.8 bits (188), Expect = 3e-14
Identities = 58/180 (32%), Positives = 85/180 (47%), Gaps = 4/180 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA+ AS GH+ I+K L+K DV + + A F +++ L R AD+
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 523
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L IA KG+L VV+ LLD G + G T LH A ++ LL
Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLL 583
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA---RPEVTRAEAIEAYELLGASFAND 280
+ GA + +TN NG L AA R S + +L + RP + + + Y L + N+
Sbjct: 584 EAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Score = 52.8 bits (121), Expect = 4e-06
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 18/217 (8%)
Query: 46 EIDDLL---NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
+++DLL ++DV T + A+++G +++LL++ V +E E
Sbjct: 446 KVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQ---NVDVEAEDK------- 495
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G A+ A+ A+++ L + AD+N + TPL A +G L +VK L+ G
Sbjct: 496 -DGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGC 554
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ +T L A K D++ LL++GA V G ALH AA G+ + +
Sbjct: 555 HPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRV 614
Query: 223 LLDHGAK-MLTNE---NGMTPLQCAAERARASVVEIL 255
LL + + +E +G T L AA V E+L
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 651
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 9/170 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-- 161
EG T L A I+ L++AGADV L A G ++ L+
Sbjct: 562 EGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPR 621
Query: 162 ---ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHA 217
D K + Y T L +AA +++V + L+ G A +D + + TALH A E H
Sbjct: 622 PWIVDEKKDDGY--TALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHT 679
Query: 218 AVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+V L+ GAK+ + +++G TPL A S + L +V + +A
Sbjct: 680 QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDA 729
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 79.8 bits (188), Expect = 3e-14
Identities = 58/180 (32%), Positives = 85/180 (47%), Gaps = 4/180 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA+ AS GH+ I+K L+K DV + + A F +++ L R AD+
Sbjct: 455 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADL 514
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ NK T L IA KG+L VV+ LLD G + G T LH A ++ LL
Sbjct: 515 NARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLL 574
Query: 225 DHGAKM-LTNENGMTPLQCAAERARASVVEILAA---RPEVTRAEAIEAYELLGASFAND 280
+ GA + +TN NG L AA R S + +L + RP + + + Y L + N+
Sbjct: 575 EAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 18/217 (8%)
Query: 46 EIDDLL---NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
+++DLL ++DV T + A+++G +++LL++ V +E E
Sbjct: 437 KVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQ---NVDVEAEDK------- 486
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G A+ A+ A+++ L + AD+N + TPL A +G L +VK L+ G
Sbjct: 487 -DGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGC 545
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ +T L A K D++ LL++GA V G ALH AA G+ + +
Sbjct: 546 HPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRV 605
Query: 223 LLDHGAK-MLTNE---NGMTPLQCAAERARASVVEIL 255
LL + + +E +G T L AA V E+L
Sbjct: 606 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELL 642
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 9/170 (5%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-- 161
EG T L A I+ L++AGADV L A G ++ L+
Sbjct: 553 EGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPR 612
Query: 162 ---ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHA 217
D K + Y T L +AA +++V + L+ G A +D + + TALH A E H
Sbjct: 613 PWIVDEKKDDGY--TALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHT 670
Query: 218 AVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEA 266
+V L+ GAK+ + +++G TPL A S + L +V + +A
Sbjct: 671 QIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQDMQDVGKVDA 720
>BC031303-1|AAH31303.1| 183|Homo sapiens ankyrin repeat domain 39
protein.
Length = 183
Score = 79.4 bits (187), Expect = 4e-14
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
+A G L VK+L++ D + + T L A+ G+ V QFLL+SGA+ D +
Sbjct: 37 SAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHG 96
Query: 204 GATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVVEILAARPEVT 262
GATALH A+ CGH + LL HG+ + +++GMT L AAER + +L
Sbjct: 97 GATALHRASYCGHTEITRLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQHSPAL 156
Query: 263 RA 264
+A
Sbjct: 157 KA 158
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 6/152 (3%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
+W A+ G L VK L++ D + T L A G + ++L+ GA
Sbjct: 35 IWSAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQT 94
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLD 225
T L A+Y G+ ++ + LL G+ VDD G T+LH AAE GH + LL
Sbjct: 95 HGGATALHRASYCGHTEITRLLLSHGSNPRVVDDD---GMTSLHKAAERGHGDICSLLLQ 151
Query: 226 HGAKMLTNENGMTPLQCAAERARASVVEILAA 257
H + + L C + + ++L++
Sbjct: 152 HSPALKAIRDRKARLACDLLPCNSDLRDLLSS 183
Score = 48.4 bits (110), Expect = 8e-05
Identities = 29/87 (33%), Positives = 46/87 (52%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL AS GH A+ + L+++GA + T +T L A + G +I + L+ HG++
Sbjct: 64 GYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEITRLLLSHGSNP 123
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL 191
+ T L AA +G+ D+ LL
Sbjct: 124 RVVDDDGMTSLHKAAERGHGDICSLLL 150
Score = 33.9 bits (74), Expect = 1.8
Identities = 23/68 (33%), Positives = 29/68 (42%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLD 152
E K D GATAL AS GH I + L+ G++ T L A G D
Sbjct: 85 ESGAKCDAQTHGGATALHRASYCGHTEITRLLLSHGSNPRVVDDDGMTSLHKAAERGHGD 144
Query: 153 IVKYLVRH 160
I L++H
Sbjct: 145 ICSLLLQH 152
>AC092636-4|AAY14966.1| 183|Homo sapiens unknown protein.
Length = 183
Score = 79.4 bits (187), Expect = 4e-14
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
+A G L VK+L++ D + + T L A+ G+ V QFLL+SGA+ D +
Sbjct: 37 SAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHG 96
Query: 204 GATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVVEILAARPEVT 262
GATALH A+ CGH + LL HG+ + +++GMT L AAER + +L
Sbjct: 97 GATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQHSPAL 156
Query: 263 RA 264
+A
Sbjct: 157 KA 158
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 6/152 (3%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
+W A+ G L VK L++ D + T L A G + ++L+ GA
Sbjct: 35 IWSAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQT 94
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLD 225
T L A+Y G+ ++ + LL G+ VDD G T+LH AAE GH + LL
Sbjct: 95 HGGATALHRASYCGHTEIARLLLSHGSNPRVVDDD---GMTSLHKAAERGHGDICSLLLQ 151
Query: 226 HGAKMLTNENGMTPLQCAAERARASVVEILAA 257
H + + L C + + ++L++
Sbjct: 152 HSPALKAIRDRKARLACDLLPCNSDLRDLLSS 183
Score = 48.4 bits (110), Expect = 8e-05
Identities = 29/87 (33%), Positives = 46/87 (52%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL AS GH A+ + L+++GA + T +T L A + G +I + L+ HG++
Sbjct: 64 GYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNP 123
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL 191
+ T L AA +G+ D+ LL
Sbjct: 124 RVVDDDGMTSLHKAAERGHGDICSLLL 150
Score = 33.9 bits (74), Expect = 1.8
Identities = 23/68 (33%), Positives = 29/68 (42%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLD 152
E K D GATAL AS GH I + L+ G++ T L A G D
Sbjct: 85 ESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGD 144
Query: 153 IVKYLVRH 160
I L++H
Sbjct: 145 ICSLLLQH 152
>AB209367-1|BAD92604.1| 192|Homo sapiens hypothetical protein
MGC41816 variant protein.
Length = 192
Score = 79.4 bits (187), Expect = 4e-14
Identities = 44/122 (36%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
+A G L VK+L++ D + + T L A+ G+ V QFLL+SGA+ D +
Sbjct: 46 SAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHG 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAAERARASVVEILAARPEVT 262
GATALH A+ CGH + LL HG+ + +++GMT L AAER + +L
Sbjct: 106 GATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQHSPAL 165
Query: 263 RA 264
+A
Sbjct: 166 KA 167
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 6/152 (3%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
+W A+ G L VK L++ D + T L A G + ++L+ GA
Sbjct: 44 IWSAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQT 103
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLD 225
T L A+Y G+ ++ + LL G+ VDD G T+LH AAE GH + LL
Sbjct: 104 HGGATALHRASYCGHTEIARLLLSHGSNPRVVDDD---GMTSLHKAAERGHGDICSLLLQ 160
Query: 226 HGAKMLTNENGMTPLQCAAERARASVVEILAA 257
H + + L C + + ++L++
Sbjct: 161 HSPALKAIRDRKARLACDLLPCNSDLRDLLSS 192
Score = 48.4 bits (110), Expect = 8e-05
Identities = 29/87 (33%), Positives = 46/87 (52%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL AS GH A+ + L+++GA + T +T L A + G +I + L+ HG++
Sbjct: 73 GYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNP 132
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLL 191
+ T L AA +G+ D+ LL
Sbjct: 133 RVVDDDGMTSLHKAAERGHGDICSLLL 159
Score = 33.9 bits (74), Expect = 1.8
Identities = 23/68 (33%), Positives = 29/68 (42%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLD 152
E K D GATAL AS GH I + L+ G++ T L A G D
Sbjct: 94 ESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGD 153
Query: 153 IVKYLVRH 160
I L++H
Sbjct: 154 ICSLLLQH 161
>BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein.
Length = 716
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 195 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 254
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 255 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 314
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 315 SDINIRDNEENICLHWAAFSGCVDIAEILLA 345
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 160 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 219
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 220 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 279
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 280 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 313
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 226 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 285
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 286 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 345
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 346 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 405
Query: 285 CLRMA 289
L+M+
Sbjct: 406 ALQMS 410
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 254 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 303
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 304 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 363
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 364 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 398
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 286 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 334
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 335 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 394
Query: 176 MIAA 179
A+
Sbjct: 395 QCAS 398
>AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone
methyltransferase 1 protein.
Length = 1267
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 866 SDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 864
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 285 CLRMA 289
L+M+
Sbjct: 957 ALQMS 961
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 805 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 854
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 855 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 914
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 915 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 885
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 886 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Query: 176 MIAA 179
A+
Sbjct: 946 QCAS 949
>AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 866 SDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 864
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 285 CLRMA 289
L+M+
Sbjct: 957 ALQMS 961
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 805 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 854
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 855 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 914
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 915 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 885
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 886 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Query: 176 MIAA 179
A+
Sbjct: 946 QCAS 949
>AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 746 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 805
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 806 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 865
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 866 SDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 830
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 831 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 864
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 777 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 836
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 896
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 897 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 956
Query: 285 CLRMA 289
L+M+
Sbjct: 957 ALQMS 961
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 805 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 854
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 855 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 914
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 915 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 949
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 837 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 885
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 886 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Query: 176 MIAA 179
A+
Sbjct: 946 QCAS 949
>AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein.
Length = 803
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 396 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 455
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 456 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 515
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 516 SDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 481 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 514
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 427 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 486
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 547 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 606
Query: 285 CLRMA 289
L+M+
Sbjct: 607 ALQMS 611
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 455 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 504
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 505 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 564
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 565 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 599
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 535
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 536 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 595
Query: 176 MIAA 179
A+
Sbjct: 596 QCAS 599
>AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein.
Length = 917
Score = 78.2 bits (184), Expect = 9e-14
Identities = 53/151 (35%), Positives = 80/151 (52%), Gaps = 2/151 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ AGH+ I LV+AGA+++ + TPL A L+ VKYL++ GA + +
Sbjct: 396 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKD 455
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+TCL +AA KG+ +VVQ+LL +G V+ + G T + +A E H +V LL G
Sbjct: 456 AEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKG 515
Query: 228 AKMLTNENGMT-PLQCAAERARASVVEILAA 257
+ + +N L AA + EIL A
Sbjct: 516 SDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/154 (33%), Positives = 82/154 (53%), Gaps = 4/154 (2%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ ++ G L V ++ G D N + +PL AA G +DI LV+ GA+I
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
++ T LM AA +L+ V++L+ +GA VD + G+T LH AA+ GH VV LL +
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSN 480
Query: 227 GAKMLT--NENGMTPLQCAAERARASVVEILAAR 258
G + ++ G TP+ A E +V++L ++
Sbjct: 481 GQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 514
Score = 58.8 bits (136), Expect = 6e-08
Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-ADIH 165
T L A+ HL VK L+KAGA V+ ST L A +G ++V+YL+ +G D++
Sbjct: 427 TPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVN 486
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ T ++ A ++D+V+ LL G+ ++ R LH+AA G + LL
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLA 546
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYY 284
+ N +G +PL AA R V + +R + E L + N + +
Sbjct: 547 AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWS 606
Query: 285 CLRMA 289
L+M+
Sbjct: 607 ALQMS 611
Score = 46.8 bits (106), Expect = 2e-04
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 10/155 (6%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGH 117
D T L AA+ G V+ LL + V + +G G T + A+ H
Sbjct: 455 DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----------GWTPMIWATEYKH 504
Query: 118 LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMI 177
+ +VK L+ G+D+N + L A F G +DI + L+ D+H N + ++ L I
Sbjct: 505 VDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHI 564
Query: 178 AAYKGYLDVVQFLLDSGARVDDRALCGATALHFAA 212
AA + D V L + V + G T L A+
Sbjct: 565 AARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 599
Score = 32.7 bits (71), Expect = 4.3
Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TP+I A + V++LL K ++ ++ +E E W A+ +
Sbjct: 487 CQDDGGWTPMIWATEYKHVDLVKLLLSK-------GSDINIRDNE---ENICLHW-AAFS 535
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
G + I + L+ A D++ +PL A E R D V + +D+ NK T L
Sbjct: 536 GCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 595
Query: 176 MIAA 179
A+
Sbjct: 596 QCAS 599
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Query: 81 LEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVST 140
LE+ + + + + D+ + TAL A AGH IV+ L++ G VN +
Sbjct: 19 LEELKESILADKSLATRTDQ---DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 141 PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
PL A GR +IVK L+ GA ++ N+ T L AA K ++ LL+ GA D +
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
Query: 201 ALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
ATA+H AA G+ ++ LL + A + + G TPL A + R ++L ++
Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G + L A+ AG IVK L+ GA VN + TPL A + R +I L+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ Y T + AA KG L ++ LL A + + G T LH A + L+
Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
Query: 225 DHGAKM-LTNENGMTPLQCA 243
GA + + N+ TPLQ A
Sbjct: 193 SQGASIYIENKEEKTPLQVA 212
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/169 (28%), Positives = 72/169 (42%), Gaps = 27/169 (15%)
Query: 44 TDEIDDLLNIDVC---SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTV---- 96
T+ ++ LL + V D +PL AA GR+ V+ LL K + G
Sbjct: 53 TEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHY 112
Query: 97 -------KFDEYVIEG-----------ATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
+ ++EG ATA+ A+ G+L ++ L+ A N
Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
+TPL AC E R++ K LV GA I+ NK T L +A KG L ++
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLI 219
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Query: 81 LEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVST 140
LE+ + + + + D+ + TAL A AGH IV+ L++ G VN +
Sbjct: 19 LEELKESILADKSLATRTDQ---DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 141 PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
PL A GR +IVK L+ GA ++ N+ T L AA K ++ LL+ GA D +
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
Query: 201 ALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
ATA+H AA G+ ++ LL + A + + G TPL A + R ++L ++
Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
Score = 46.0 bits (104), Expect = 4e-04
Identities = 42/126 (33%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 62 CTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIV 121
CTPL AA R +LLE P D Y ATA+ A+ G+L ++
Sbjct: 107 CTPLHYAASKNRHEIAVMLLEGGANPDAK--------DHYE---ATAMHRAAAKGNLKMI 155
Query: 122 KRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
L+ A N +TPL AC E R++ K LV G I+ NK T L +A K
Sbjct: 156 HILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYIENKEEKTPLQVA--K 213
Query: 182 GYLDVV 187
G L ++
Sbjct: 214 GGLGLI 219
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Query: 81 LEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVST 140
LE+ + + + + D+ + TAL A AGH IV+ L++ G VN +
Sbjct: 19 LEELKESILADKSLATRTDQ---DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 141 PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
PL A GR +IVK L+ GA ++ N+ T L AA K ++ LL+ GA D +
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
Query: 201 ALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
ATA+H AA G+ ++ LL + A + + G TPL A + R ++L ++
Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G + L A+ AG IVK L+ GA VN + TPL A + R +I L+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ Y T + AA KG L ++ LL A + + G T LH A + L+
Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
Query: 225 DHGAKM-LTNENGMTPLQCA 243
GA + + N+ TPLQ A
Sbjct: 193 SQGASIYIENKEEKTPLQVA 212
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/169 (28%), Positives = 72/169 (42%), Gaps = 27/169 (15%)
Query: 44 TDEIDDLLNIDVC---SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTV---- 96
T+ ++ LL + V D +PL AA GR+ V+ LL K + G
Sbjct: 53 TEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHY 112
Query: 97 -------KFDEYVIEG-----------ATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
+ ++EG ATA+ A+ G+L ++ L+ A N
Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
+TPL AC E R++ K LV GA I+ NK T L +A KG L ++
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLI 219
>AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Query: 81 LEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVST 140
LE+ + + + + D+ + TAL A AGH IV+ L++ G VN +
Sbjct: 19 LEELKESILADKSLATRTDQ---DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 141 PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
PL A GR +IVK L+ GA ++ N+ T L AA K ++ LL+ GA D +
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
Query: 201 ALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
ATA+H AA G+ ++ LL + A + + G TPL A + R ++L ++
Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G + L A+ AG IVK L+ GA VN + TPL A + R +I L+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ Y T + AA KG L ++ LL A + + G T LH A + L+
Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
Query: 225 DHGAKM-LTNENGMTPLQCA 243
GA + + N+ TPLQ A
Sbjct: 193 SQGASIYIENKEEKTPLQVA 212
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/169 (28%), Positives = 72/169 (42%), Gaps = 27/169 (15%)
Query: 44 TDEIDDLLNIDVC---SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTV---- 96
T+ ++ LL + V D +PL AA GR+ V+ LL K + G
Sbjct: 53 TEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHY 112
Query: 97 -------KFDEYVIEG-----------ATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
+ ++EG ATA+ A+ G+L ++ L+ A N
Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
+TPL AC E R++ K LV GA I+ NK T L +A KG L ++
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLI 219
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 77.8 bits (183), Expect = 1e-13
Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 12/194 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA++G +G R+LL+ C++ + EG T L A+ + +
Sbjct: 431 PLHFAAQNGDDGTARLLLDH---GACVDAQER--------EGWTPLHLAAQNNFENVARL 479
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
LV AD N TPL A + G + +VK L GA++ + T L +A +G
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQC 242
+ +Q LL SGA D G LH AA G + LL +GA + L G TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHL 599
Query: 243 AAERARASVVEILA 256
AA + ++ +LA
Sbjct: 600 AAYKGHLEIIHLLA 613
Score = 77.8 bits (183), Expect = 1e-13
Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A G + ++ L+K+GA + ++ PL A G+ I K L+R+GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
T L +AAYKG+L+++ L +S A + T LH AA G AVV +LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 227 GA-KMLTNENGMTPLQCAAERAR-ASVVEIL 255
GA ++G TPL A +R+ SV+ +L
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Score = 70.1 bits (164), Expect = 2e-11
Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A G+ A++ LL+ P L+ G L A+ G I K
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGY-----------GPLHTAAARGKYLICK 577
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T TPL A ++G L+I+ L A++ N T L +AA G
Sbjct: 578 MLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHG 637
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
VV LL GA + G T LH A + V +LL+H A + N+ G TP
Sbjct: 638 EEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAH 697
Query: 242 CAAERARASVVEIL 255
AA + +++++L
Sbjct: 698 LAALKGNTAILKVL 711
Score = 62.5 bits (145), Expect = 5e-09
Identities = 68/259 (26%), Positives = 100/259 (38%), Gaps = 18/259 (6%)
Query: 40 YEKKTDEIDDLLNI-----DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEG 94
Y K+ ++ D N+ ++C K TPL G VR+LL
Sbjct: 336 YLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH----------- 384
Query: 95 TVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIV 154
V D G T L A+ + L+ GAD N PL A G
Sbjct: 385 EVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTA 444
Query: 155 KYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC 214
+ L+ HGA + + T L +AA + +V + L+ A + G T LH AA
Sbjct: 445 RLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYF 504
Query: 215 GHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVEILAARPEVTRAEAIEAYELL 273
GH ++V L GA++ + + TPL A ER + ++ L V A Y L
Sbjct: 505 GHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPL 564
Query: 274 GASFANDKEYYCLRMAYQY 292
+ A K C +M +Y
Sbjct: 565 HTAAARGKYLIC-KMLLRY 582
Score = 61.7 bits (143), Expect = 8e-09
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GHL I+ L ++ A++ TPL A G +V L++ GAD
Sbjct: 592 QGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGAD 651
Query: 164 IHKANKYNNTCLMIAAYKG-YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A + T L +A + +L V+ LL+ A V R G T H AA G+ A++
Sbjct: 652 PNAAEQSGWTPLHLAVQRSTFLSVIN-LLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEILAAR 258
L++ GA++ + TPLQ A + ++ L +
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGK 747
Score = 39.5 bits (88), Expect = 0.037
Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 11/131 (8%)
Query: 60 VKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLA 119
V TPL AARHG E V LL+ P E G T L A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW-----------TPLHLAVQRSTFL 673
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
V L++ A+V+ + TP A +G I+K LV GA + + + T L +A
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Query: 180 YKGYLDVVQFL 190
++ FL
Sbjct: 734 RSRKQGIMSFL 744
Score = 32.7 bits (71), Expect = 4.3
Identities = 16/26 (61%), Positives = 19/26 (73%)
Query: 539 TSRLLLDCGADVDAADMNRRTPLHVA 564
T+RLLLD GA VDA + TPLH+A
Sbjct: 443 TARLLLDHGACVDAQEREGWTPLHLA 468
Score = 31.5 bits (68), Expect = 9.9
Identities = 13/23 (56%), Positives = 18/23 (78%)
Query: 543 LLDCGADVDAADMNRRTPLHVAL 565
LL CGAD +AA+ + TPLH+A+
Sbjct: 645 LLQCGADPNAAEQSGWTPLHLAV 667
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 77.8 bits (183), Expect = 1e-13
Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 12/194 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA++G +G R+LL+ C++ + EG T L A+ + +
Sbjct: 431 PLHFAAQNGDDGTARLLLDH---GACVDAQER--------EGWTPLHLAAQNNFENVARL 479
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
LV AD N TPL A + G + +VK L GA++ + T L +A +G
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQC 242
+ +Q LL SGA D G LH AA G + LL +GA + L G TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHL 599
Query: 243 AAERARASVVEILA 256
AA + ++ +LA
Sbjct: 600 AAYKGHLEIIHLLA 613
Score = 77.8 bits (183), Expect = 1e-13
Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A G + ++ L+K+GA + ++ PL A G+ I K L+R+GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
T L +AAYKG+L+++ L +S A + T LH AA G AVV +LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 227 GA-KMLTNENGMTPLQCAAERAR-ASVVEIL 255
GA ++G TPL A +R+ SV+ +L
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Score = 70.1 bits (164), Expect = 2e-11
Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A G+ A++ LL+ P L+ G L A+ G I K
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGY-----------GPLHTAAARGKYLICK 577
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T TPL A ++G L+I+ L A++ N T L +AA G
Sbjct: 578 MLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHG 637
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
VV LL GA + G T LH A + V +LL+H A + N+ G TP
Sbjct: 638 EEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAH 697
Query: 242 CAAERARASVVEIL 255
AA + +++++L
Sbjct: 698 LAALKGNTAILKVL 711
Score = 62.5 bits (145), Expect = 5e-09
Identities = 68/259 (26%), Positives = 100/259 (38%), Gaps = 18/259 (6%)
Query: 40 YEKKTDEIDDLLNI-----DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEG 94
Y K+ ++ D N+ ++C K TPL G VR+LL
Sbjct: 336 YLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH----------- 384
Query: 95 TVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIV 154
V D G T L A+ + L+ GAD N PL A G
Sbjct: 385 EVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTA 444
Query: 155 KYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC 214
+ L+ HGA + + T L +AA + +V + L+ A + G T LH AA
Sbjct: 445 RLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYF 504
Query: 215 GHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVEILAARPEVTRAEAIEAYELL 273
GH ++V L GA++ + + TPL A ER + ++ L V A Y L
Sbjct: 505 GHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPL 564
Query: 274 GASFANDKEYYCLRMAYQY 292
+ A K C +M +Y
Sbjct: 565 HTAAARGKYLIC-KMLLRY 582
Score = 61.7 bits (143), Expect = 8e-09
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GHL I+ L ++ A++ TPL A G +V L++ GAD
Sbjct: 592 QGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGAD 651
Query: 164 IHKANKYNNTCLMIAAYKG-YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A + T L +A + +L V+ LL+ A V R G T H AA G+ A++
Sbjct: 652 PNAAEQSGWTPLHLAVQRSTFLSVIN-LLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEILAAR 258
L++ GA++ + TPLQ A + ++ L +
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGK 747
Score = 39.5 bits (88), Expect = 0.037
Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 11/131 (8%)
Query: 60 VKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLA 119
V TPL AARHG E V LL+ P E G T L A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW-----------TPLHLAVQRSTFL 673
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
V L++ A+V+ + TP A +G I+K LV GA + + + T L +A
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Query: 180 YKGYLDVVQFL 190
++ FL
Sbjct: 734 RSRKQGIMSFL 744
Score = 32.7 bits (71), Expect = 4.3
Identities = 16/26 (61%), Positives = 19/26 (73%)
Query: 539 TSRLLLDCGADVDAADMNRRTPLHVA 564
T+RLLLD GA VDA + TPLH+A
Sbjct: 443 TARLLLDHGACVDAQEREGWTPLHLA 468
Score = 31.5 bits (68), Expect = 9.9
Identities = 13/23 (56%), Positives = 18/23 (78%)
Query: 543 LLDCGADVDAADMNRRTPLHVAL 565
LL CGAD +AA+ + TPLH+A+
Sbjct: 645 LLQCGADPNAAEQSGWTPLHLAV 667
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 77.8 bits (183), Expect = 1e-13
Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 12/194 (6%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA++G +G R+LL+ C++ + EG T L A+ + +
Sbjct: 431 PLHFAAQNGDDGTARLLLDH---GACVDAQER--------EGWTPLHLAAQNNFENVARL 479
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
LV AD N TPL A + G + +VK L GA++ + T L +A +G
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQC 242
+ +Q LL SGA D G LH AA G + LL +GA + L G TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHL 599
Query: 243 AAERARASVVEILA 256
AA + ++ +LA
Sbjct: 600 AAYKGHLEIIHLLA 613
Score = 77.8 bits (183), Expect = 1e-13
Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A G + ++ L+K+GA + ++ PL A G+ I K L+R+GA +
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLEL 588
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
T L +AAYKG+L+++ L +S A + T LH AA G AVV +LL
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQC 648
Query: 227 GA-KMLTNENGMTPLQCAAERAR-ASVVEIL 255
GA ++G TPL A +R+ SV+ +L
Sbjct: 649 GADPNAAEQSGWTPLHLAVQRSTFLSVINLL 679
Score = 70.1 bits (164), Expect = 2e-11
Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 12/194 (6%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A G+ A++ LL+ P L+ G L A+ G I K
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGY-----------GPLHTAAARGKYLICK 577
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA + T TPL A ++G L+I+ L A++ N T L +AA G
Sbjct: 578 MLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHG 637
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
VV LL GA + G T LH A + V +LL+H A + N+ G TP
Sbjct: 638 EEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAH 697
Query: 242 CAAERARASVVEIL 255
AA + +++++L
Sbjct: 698 LAALKGNTAILKVL 711
Score = 62.5 bits (145), Expect = 5e-09
Identities = 68/259 (26%), Positives = 100/259 (38%), Gaps = 18/259 (6%)
Query: 40 YEKKTDEIDDLLNI-----DVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEG 94
Y K+ ++ D N+ ++C K TPL G VR+LL
Sbjct: 336 YLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH----------- 384
Query: 95 TVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIV 154
V D G T L A+ + L+ GAD N PL A G
Sbjct: 385 EVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTA 444
Query: 155 KYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAEC 214
+ L+ HGA + + T L +AA + +V + L+ A + G T LH AA
Sbjct: 445 RLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYF 504
Query: 215 GHAAVVCSLLDHGAKMLTNENGM-TPLQCAAERARASVVEILAARPEVTRAEAIEAYELL 273
GH ++V L GA++ + + TPL A ER + ++ L V A Y L
Sbjct: 505 GHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPL 564
Query: 274 GASFANDKEYYCLRMAYQY 292
+ A K C +M +Y
Sbjct: 565 HTAAARGKYLIC-KMLLRY 582
Score = 61.7 bits (143), Expect = 8e-09
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G T L A+ GHL I+ L ++ A++ TPL A G +V L++ GAD
Sbjct: 592 QGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGAD 651
Query: 164 IHKANKYNNTCLMIAAYKG-YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
+ A + T L +A + +L V+ LL+ A V R G T H AA G+ A++
Sbjct: 652 PNAAEQSGWTPLHLAVQRSTFLSVIN-LLEHHANVHARNKVGWTPAHLAALKGNTAILKV 710
Query: 223 LLDHGAKMLTNEN-GMTPLQCAAERARASVVEILAAR 258
L++ GA++ + TPLQ A + ++ L +
Sbjct: 711 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGK 747
Score = 39.5 bits (88), Expect = 0.037
Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 11/131 (8%)
Query: 60 VKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLA 119
V TPL AARHG E V LL+ P E G T L A
Sbjct: 625 VNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW-----------TPLHLAVQRSTFL 673
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
V L++ A+V+ + TP A +G I+K LV GA + + + T L +A
Sbjct: 674 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Query: 180 YKGYLDVVQFL 190
++ FL
Sbjct: 734 RSRKQGIMSFL 744
Score = 32.7 bits (71), Expect = 4.3
Identities = 16/26 (61%), Positives = 19/26 (73%)
Query: 539 TSRLLLDCGADVDAADMNRRTPLHVA 564
T+RLLLD GA VDA + TPLH+A
Sbjct: 443 TARLLLDHGACVDAQEREGWTPLHLA 468
Score = 31.5 bits (68), Expect = 9.9
Identities = 13/23 (56%), Positives = 18/23 (78%)
Query: 543 LLDCGADVDAADMNRRTPLHVAL 565
LL CGAD +AA+ + TPLH+A+
Sbjct: 645 LLQCGADPNAAEQSGWTPLHLAV 667
>AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containing
protein ASB-2 protein.
Length = 544
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/169 (32%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL + L +++ LV GA V + TPL A G+L+ +++L ++GADI
Sbjct: 149 GWTALHESVSRNDLEVMQILVSGGAKVE-SKNAYGTPLFVAAQSGQLEALRFLAKYGADI 207
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N + L A + +VV+FLL GA + G LH A++ G+ +V LL
Sbjct: 208 NTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLL 267
Query: 225 DHGAKMLTNENGMTPLQCAAERARASVVE-ILAARPEVTRAEAIEAYEL 272
++ +G++PL AAER V+E +L+AR +V A E L
Sbjct: 268 PVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARL 316
Score = 77.4 bits (182), Expect = 2e-13
Identities = 59/197 (29%), Positives = 101/197 (51%), Gaps = 14/197 (7%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PL AA +G+ G +++L + GT+ D+ ++ TA++ A+ GHL +
Sbjct: 52 PLHEAAYYGQVGCLKVLQRAY--------PGTI--DQRTLQEETAVYLATCRGHLDCLLS 101
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI-HKANKYNNTCLMIAAYKG 182
L++AGA+ + + ++ TPL AC + VK LV+H AD H+ N+ T L + +
Sbjct: 102 LLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNR-GWTALHESVSRN 160
Query: 183 YLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-ENGMTPLQ 241
L+V+Q L+ GA+V+ + G T L AA+ G + L +GA + T + + L
Sbjct: 161 DLEVMQILVSGGAKVESKNAYG-TPLFVAAQSGQLEALRFLAKYGADINTQASDNASALY 219
Query: 242 CAAERARASVVEILAAR 258
A + VVE L ++
Sbjct: 220 EACKNEHEEVVEFLLSQ 236
Score = 50.8 bits (116), Expect = 2e-05
Identities = 54/219 (24%), Positives = 89/219 (40%), Gaps = 10/219 (4%)
Query: 64 PLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKR 123
PLI A + G E A++ ++++ + EG + E G G L +++R
Sbjct: 19 PLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQV--------GCLKVLQR 70
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
D T T + A G LD + L++ GA+ +NK T L A +
Sbjct: 71 AYPGTID--QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKN 128
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCA 243
+ V+ L+ A + R G TALH + V+ L+ GAK+ + TPL A
Sbjct: 129 AEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGTPLFVA 188
Query: 244 AERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
A+ + + LA +A + L + N+ E
Sbjct: 189 AQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHE 227
Score = 41.9 bits (94), Expect = 0.007
Identities = 56/204 (27%), Positives = 91/204 (44%), Gaps = 27/204 (13%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL AA+ G+ A+R L K+ + T+ + + A+AL+ A H +V+
Sbjct: 183 TPLFVAAQSGQLEALRFLA-KYGADI--NTQAS--------DNASALYEACKNEHEEVVE 231
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV---------RHG-ADIHKANKYNN 172
L+ GAD N + PL A +G IV+ L+ R G + +H A + N+
Sbjct: 232 FLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGVSPLHLAAERNH 291
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARV-DDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
++ A DV L AR+ +DR ++AL+FA + LL HGA
Sbjct: 292 DEVLEALLSARFDVNTPLAPERARLYEDRR---SSALYFAVVNNNVYATELLLQHGAD-- 346
Query: 232 TNENGMTPLQCAAERARASVVEIL 255
N + ++PL A +++L
Sbjct: 347 PNRDVISPLLVAIRHGCLRTMQLL 370
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Query: 81 LEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVST 140
LE+ + + + + D+ + TAL A AGH IV+ L++ G VN +
Sbjct: 19 LEELKESILADKSLATRTDQ---DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 141 PLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDR 200
PL A GR +IVK L+ GA ++ N+ T L AA K ++ LL+ GA D +
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAK 135
Query: 201 ALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAAR 258
ATA+H AA G+ ++ LL + A + + G TPL A + R ++L ++
Sbjct: 136 DHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 194
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G + L A+ AG IVK L+ GA VN + TPL A + R +I L+ GA+
Sbjct: 73 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ Y T + AA KG L ++ LL A + + G T LH A + L+
Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
Query: 225 DHGAKM-LTNENGMTPLQCA 243
GA + + N+ TPLQ A
Sbjct: 193 SQGASIYIENKEEKTPLQVA 212
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/169 (28%), Positives = 72/169 (42%), Gaps = 27/169 (15%)
Query: 44 TDEIDDLLNIDVC---SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTV---- 96
T+ ++ LL + V D +PL AA GR+ V+ LL K + G
Sbjct: 53 TEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHY 112
Query: 97 -------KFDEYVIEG-----------ATALWCASGAGHLAIVKRLVKAGADVNHATRTV 138
+ ++EG ATA+ A+ G+L ++ L+ A N
Sbjct: 113 AASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 139 STPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
+TPL AC E R++ K LV GA I+ NK T L +A KG L ++
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA--KGGLGLI 219
>BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein.
Length = 725
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 66.1 bits (154), Expect = 4e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDQEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 77.4 bits (182), Expect = 2e-13
Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL A+G GH+A+++RLV G D+ T L +A D V+ L+R G+
Sbjct: 97 EGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGST 156
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ + N +CL AA G DV + L+ +G + GA+ LH A A+V L
Sbjct: 157 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 216
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
++ + + +N TPL AAE A + ++L
Sbjct: 217 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADML 249
Score = 72.5 bits (170), Expect = 4e-12
Identities = 51/156 (32%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHG 161
+G T L CA+ GH+ ++ +++ DV +H + T A G+LD + +LV G
Sbjct: 29 DGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSG 88
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D + +K NT L +AA +G++ V+Q L+D G ++++ G TALH AA H V
Sbjct: 89 CDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQ 148
Query: 222 SLLDHGAKM--LTNENGMTPLQCAAERARASVVEIL 255
LL G+ + LT +N ++ L AA V +L
Sbjct: 149 LLLRAGSTVNALTQKN-LSCLHYAALSGSEDVSRVL 183
Score = 68.1 bits (159), Expect = 9e-11
Identities = 46/143 (32%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKANKYNNT 173
GHL I++ LV +GA ++ ++ T L A +G + ++ +++ D+ +K T
Sbjct: 8 GHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRT 67
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LT 232
AA G LD + FL+ SG + + G TALH AA GH AV+ L+D G +
Sbjct: 68 AFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQ 127
Query: 233 NENGMTPLQCAAERARASVVEIL 255
N G+T L AA + V++L
Sbjct: 128 NAEGLTALHSAAGGSHPDCVQLL 150
Score = 60.9 bits (141), Expect = 1e-08
Identities = 56/208 (26%), Positives = 92/208 (44%), Gaps = 5/208 (2%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E EG TAL A+G H V+ L++AG+ VN T+ + L A G D+ + L+
Sbjct: 125 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 184
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
G + + + L +A + +V+ L++S + V+ T LH AAE
Sbjct: 185 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 244
Query: 219 VVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASF 277
+ LL G + L +E G T L A S+V+++ R E + G S
Sbjct: 245 IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSL 304
Query: 278 ANDKEYYCLRMAYQYLHRAMAMRYDPRY 305
+ +++ R Q L R++ R RY
Sbjct: 305 SFKQDH---RQETQQL-RSVLWRLASRY 328
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA A+ G L + LV +G D N + +T L A G + +++ LV G D+
Sbjct: 65 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 124
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N T L AA + D VQ LL +G+ V+ + LH+AA G V L+
Sbjct: 125 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 184
Query: 225 D-HGAKMLTNENGMTPLQCAAERARASVVEIL 255
G + + G +PL A ++V +L
Sbjct: 185 HAGGCANVVDHQGASPLHLAVRHNFPALVRLL 216
Score = 44.4 bits (100), Expect = 0.001
Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 3/84 (3%)
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL---LDHGAKML 231
L+++A+ G+L ++Q L++SGA++ + G T LH AA+ GH V+ + L+ A
Sbjct: 1 LLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDH 60
Query: 232 TNENGMTPLQCAAERARASVVEIL 255
++ G T AAE + ++ L
Sbjct: 61 VDKLGRTAFHRAAEHGQLDALDFL 84
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 77.4 bits (182), Expect = 2e-13
Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL A+G GH+A+++RLV G D+ T L +A D V+ L+R G+
Sbjct: 100 EGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGST 159
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ + N +CL AA G DV + L+ +G + GA+ LH A A+V L
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
++ + + +N TPL AAE A + ++L
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADML 252
Score = 72.5 bits (170), Expect = 4e-12
Identities = 51/156 (32%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHG 161
+G T L CA+ GH+ ++ +++ DV +H + T A G+LD + +LV G
Sbjct: 32 DGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSG 91
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D + +K NT L +AA +G++ V+Q L+D G ++++ G TALH AA H V
Sbjct: 92 CDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQ 151
Query: 222 SLLDHGAKM--LTNENGMTPLQCAAERARASVVEIL 255
LL G+ + LT +N ++ L AA V +L
Sbjct: 152 LLLRAGSTVNALTQKN-LSCLHYAALSGSEDVSRVL 186
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 3/151 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--H 165
AL ++ GHL I++ LV +GA ++ ++ T L A +G + ++ +++ D+
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+K T AA G LD + FL+ SG + + G TALH AA GH AV+ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + N G+T L AA + V++L
Sbjct: 123 IGLDLEEQNAEGLTALHSAAGGSHPDCVQLL 153
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 5/208 (2%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E EG TAL A+G H V+ L++AG+ VN T+ + L A G D+ + L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
G + + + L +A + +V+ L++S + V+ T LH AAE
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 219 VVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASF 277
+ LL G + L ++ G T L A S+V+++ R E + G S
Sbjct: 248 IADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSL 307
Query: 278 ANDKEYYCLRMAYQYLHRAMAMRYDPRY 305
+ +++ R Q L R++ R RY
Sbjct: 308 SFKQDH---RQETQQL-RSVLWRLASRY 331
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA A+ G L + LV +G D N + +T L A G + +++ LV G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N T L AA + D VQ LL +G+ V+ + LH+AA G V L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 225 D-HGAKMLTNENGMTPLQCAAERARASVVEIL 255
G + + G +PL A ++V +L
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 77.4 bits (182), Expect = 2e-13
Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL A+G GH+A+++RLV G D+ T L +A D V+ L+R G+
Sbjct: 100 EGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGST 159
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ + N +CL AA G DV + L+ +G + GA+ LH A A+V L
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
++ + + +N TPL AAE A + ++L
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADML 252
Score = 72.5 bits (170), Expect = 4e-12
Identities = 51/156 (32%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHG 161
+G T L CA+ GH+ ++ +++ DV +H + T A G+LD + +LV G
Sbjct: 32 DGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSG 91
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D + +K NT L +AA +G++ V+Q L+D G ++++ G TALH AA H V
Sbjct: 92 CDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQ 151
Query: 222 SLLDHGAKM--LTNENGMTPLQCAAERARASVVEIL 255
LL G+ + LT +N ++ L AA V +L
Sbjct: 152 LLLRAGSTVNALTQKN-LSCLHYAALSGSEDVSRVL 186
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 3/151 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--H 165
AL ++ GHL I++ LV +GA ++ ++ T L A +G + ++ +++ D+
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+K T AA G LD + FL+ SG + + G TALH AA GH AV+ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + N G+T L AA + V++L
Sbjct: 123 IGLDLEEQNAEGLTALHSAAGGSHPDCVQLL 153
Score = 60.9 bits (141), Expect = 1e-08
Identities = 56/208 (26%), Positives = 92/208 (44%), Gaps = 5/208 (2%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E EG TAL A+G H V+ L++AG+ VN T+ + L A G D+ + L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
G + + + L +A + +V+ L++S + V+ T LH AAE
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 219 VVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASF 277
+ LL G + L +E G T L A S+V+++ R E + G S
Sbjct: 248 IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSL 307
Query: 278 ANDKEYYCLRMAYQYLHRAMAMRYDPRY 305
+ +++ R Q L R++ R RY
Sbjct: 308 SFKQDH---RQETQQL-RSVLWRLASRY 331
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA A+ G L + LV +G D N + +T L A G + +++ LV G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N T L AA + D VQ LL +G+ V+ + LH+AA G V L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 225 D-HGAKMLTNENGMTPLQCAAERARASVVEIL 255
G + + G +PL A ++V +L
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 77.4 bits (182), Expect = 2e-13
Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 1/153 (0%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG TAL A+G GH+A+++RLV G D+ T L +A D V+ L+R G+
Sbjct: 100 EGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGST 159
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
++ + N +CL AA G DV + L+ +G + GA+ LH A A+V L
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 224 LDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
++ + + +N TPL AAE A + ++L
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADML 252
Score = 72.5 bits (170), Expect = 4e-12
Identities = 51/156 (32%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADV--NHATRTVSTPLRAACFEGRLDIVKYLVRHG 161
+G T L CA+ GH+ ++ +++ DV +H + T A G+LD + +LV G
Sbjct: 32 DGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSG 91
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D + +K NT L +AA +G++ V+Q L+D G ++++ G TALH AA H V
Sbjct: 92 CDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQ 151
Query: 222 SLLDHGAKM--LTNENGMTPLQCAAERARASVVEIL 255
LL G+ + LT +N ++ L AA V +L
Sbjct: 152 LLLRAGSTVNALTQKN-LSCLHYAALSGSEDVSRVL 186
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 3/151 (1%)
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--H 165
AL ++ GHL I++ LV +GA ++ ++ T L A +G + ++ +++ D+
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+K T AA G LD + FL+ SG + + G TALH AA GH AV+ L+D
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 122
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
G + N G+T L AA + V++L
Sbjct: 123 IGLDLEEQNAEGLTALHSAAGGSHPDCVQLL 153
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TA A+ G L + LV +G D N + +T L A G + +++ LV G D+
Sbjct: 68 GRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDL 127
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ N T L AA + D VQ LL +G+ V+ + LH+AA G V L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 225 D-HGAKMLTNENGMTPLQCAAERARASVVEIL 255
G + + G +PL A ++V +L
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Score = 50.0 bits (114), Expect = 3e-05
Identities = 37/132 (28%), Positives = 61/132 (46%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E EG TAL A+G H V+ L++AG+ VN T+ + L A G D+ + L+
Sbjct: 128 EEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLI 187
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
G + + + L +A + +V+ L++S + V+ T LH AAE
Sbjct: 188 HAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD 247
Query: 219 VVCSLLDHGAKM 230
+ LL G +
Sbjct: 248 IADMLLIAGVDL 259
Score = 33.1 bits (72), Expect = 3.2
Identities = 20/66 (30%), Positives = 31/66 (46%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+GA+ L A A+V+ L+ + +DVN TPL A DI L+ G D
Sbjct: 199 QGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVD 258
Query: 164 IHKANK 169
++ +K
Sbjct: 259 LNLRDK 264
>BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin
protein.
Length = 604
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 77.4 bits (182), Expect = 2e-13
Identities = 62/200 (31%), Positives = 91/200 (45%), Gaps = 20/200 (10%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
+PL AA HG A+ +L++ + D G T L A+ GH+ V
Sbjct: 19 SPLHLAAYHGHHQALEVLVQSL-----------LDLDVRNSSGRTPLDLAAFKGHVECVD 67
Query: 123 RLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLV-----RHGADIHKANKYNNTCLM 176
L+ GA + + TP+ AA G + ++ L+ ++ DI N T LM
Sbjct: 68 VLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN--GQTPLM 125
Query: 177 IAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNEN 235
++ G+ D V LL+ GA VD + G TALH A GH V +LL HGAK +L +
Sbjct: 126 LSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSR 185
Query: 236 GMTPLQCAAERARASVVEIL 255
G TP+ +A V+ L
Sbjct: 186 GRTPIHLSAACGHIGVLGAL 205
Score = 72.1 bits (169), Expect = 6e-12
Identities = 66/245 (26%), Positives = 107/245 (43%), Gaps = 22/245 (8%)
Query: 47 IDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGA 106
+ LL++DV + + TPL AA G V +L+ + ++ +Y+++
Sbjct: 37 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQ---------GASILVKDYILK-R 85
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS----TPLRAACFEGRLDIVKYLVRHGA 162
T + A+ GH ++ L+ A+ +A TPL + G D V L+ GA
Sbjct: 86 TPIHAAATNGHSECLRLLI-GNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 144
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ +K+ T L A G+ + V LL GA+ R G T +H +A CGH V+ +
Sbjct: 145 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 204
Query: 223 LLDHGAKMLTN-----ENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASF 277
LL A M N +G T L A + VE+L + + E A+ L +
Sbjct: 205 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEG-NAFSPLHCAV 263
Query: 278 ANDKE 282
ND E
Sbjct: 264 INDNE 268
Score = 67.3 bits (157), Expect = 2e-10
Identities = 55/200 (27%), Positives = 84/200 (42%), Gaps = 12/200 (6%)
Query: 60 VKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLA 119
+K TP+ AA +G +R+L+ P ++ + G T L + GH
Sbjct: 83 LKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDG--------NGQTPLMLSVLNGHTD 134
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
V L+ GA+V+ + T L G + V L++HGA + T + ++A
Sbjct: 135 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 194
Query: 180 YKGYLDVVQFLLDSGARVDDRALC----GATALHFAAECGHAAVVCSLLDHGAKMLTNEN 235
G++ V+ LL S A +D G TALH+A GH V LL+ T N
Sbjct: 195 ACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGN 254
Query: 236 GMTPLQCAAERARASVVEIL 255
+PL CA E+L
Sbjct: 255 AFSPLHCAVINDNEGAAEML 274
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L A +G E V +LLE+ V +TEG + L CA + +
Sbjct: 225 TALHWACYNGHETCVELLLEQ---EVFQKTEGNA---------FSPLHCAVINDNEGAAE 272
Query: 123 RLVKA-GADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
L+ GA + +AT + TPL AA F ++ ++ L+ H A ++ + T LM+AA
Sbjct: 273 MLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAE 332
Query: 181 KGYLDVVQFLLDS-GARVDDRALCGATALHFAAECGHAA----VVCSLLDHGAKMLTNEN 235
G + V+ L+ S A + + TALH A GH ++ + D TN
Sbjct: 333 NGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAA 392
Query: 236 GMTPLQCAAERARASVVEILAAR 258
TPL AA VV+ L +
Sbjct: 393 LQTPLHVAARNGLTMVVQELLGK 415
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
Query: 136 RTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGA 195
R +PL A + G ++ LV+ D+ N T L +AA+KG+++ V L++ GA
Sbjct: 15 RATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGA 74
Query: 196 RVDDR-ALCGATALHFAAECGHAAVVCSLLDH----GAKMLTNENGMTPL 240
+ + + T +H AA GH+ + L+ + A + + NG TPL
Sbjct: 75 SILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPL 124
Score = 46.4 bits (105), Expect = 3e-04
Identities = 47/172 (27%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Query: 90 LETEGTVKFDEYVIEGATA-LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFE 148
+ET GT + + L A+ GH ++ LV++ D++ + TPL A F+
Sbjct: 1 METSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFK 60
Query: 149 GRLDIVKYLVRHGADI-HKANKYNNTCLMIAAYKGYLDVVQFLLDSGA---RVDDRALCG 204
G ++ V L+ GA I K T + AA G+ + ++ L+ + VD + G
Sbjct: 61 GHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNG 120
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
T L + GH V SLL+ GA + + G T L A V+ L
Sbjct: 121 QTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 172
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N+ + L +AAY G+ ++ L+ S +D R G T L AA GH V L++ G
Sbjct: 14 NRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQG 73
Query: 228 AKMLTNENGM--TPLQCAAERARASVVEILAARPEVTRAEAIE 268
A +L + + TP+ AA + + +L E A I+
Sbjct: 74 ASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQ 116
Score = 33.9 bits (74), Expect = 1.8
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 105 GATALWCASGAGHLAIVKRLVK-AGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
G T L A+ G V+ LV A A++ + +T L AC +G ++ D
Sbjct: 323 GKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITD 382
Query: 164 IHKANKYN---NTCLMIAAYKGYLDVVQFLLDSGARV 197
+ N N T L +AA G VVQ LL GA V
Sbjct: 383 RNLINATNAALQTPLHVAARNGLTMVVQELLGKGASV 419
>AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein.
Length = 895
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein
alternative isoform protein.
Length = 895
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 253 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 304
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 305 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 464
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 357 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 416
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 417 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 476
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 477 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 373 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 432
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 433 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 492
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 493 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543
Score = 40.3 bits (90), Expect = 0.021
Identities = 42/166 (25%), Positives = 66/166 (39%), Gaps = 3/166 (1%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A L L+KAGADVN + T L A +G +K L+ A+
Sbjct: 48 GRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANW 107
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCS 222
+ + T L + + LL + VD + TALH++A + V
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
L+ H + + + + G PL AA S V + + E++
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 213
Score = 37.5 bits (83), Expect = 0.15
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 134 ATRTVSTPLRAACFEG-RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLD 192
A ++++ + AA G + + + +V + A K +++ T LM LD LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 193 SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASV 251
+GA V+ TALH AA+ G+ + LL A + + MTPL
Sbjct: 70 AGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKC 129
Query: 252 VEIL 255
+ +L
Sbjct: 130 LALL 133
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 257 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 314
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 488 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 548 ALSIAAIQDIAAFKIQAVYKGY 569
>AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog
protein.
Length = 1013
Score = 77.4 bits (182), Expect = 2e-13
Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 22/231 (9%)
Query: 17 NSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARHGREGA 76
N R + +AA G + ++ LL K+ I SD TPL AA+
Sbjct: 201 NLFRTPLHWAALLGHAQIVHLLLERNKSGTIP--------SDSQGATPLHYAAQSNFAET 252
Query: 77 VRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLV--KAGADVNHA 134
V++ L+ +VK D+ +EG T+ A+G G +++ ++ K+ D+N A
Sbjct: 253 VKVFLK----------HPSVK-DDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 301
Query: 135 TRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSG 194
+ T L AA G + VK L+ + A + + +T L A G+ DV+Q L+ G
Sbjct: 302 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 361
Query: 195 ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAK-MLTNENGMTPLQCAA 244
ARVD G + LH+AA G+A V L+++ + + G TPLQCAA
Sbjct: 362 ARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAA 412
Score = 65.7 bits (153), Expect = 5e-10
Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ +GH++ VK L++ A V+ TPL AC G D+++ L++ GA +
Sbjct: 305 GGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARV 364
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
++ ++ L AA G DV Q L+++ + + G T L AA G+ + L+
Sbjct: 365 DLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLM 424
Query: 225 DHGA-KMLTNENGMTPLQCAAERARASVVEIL 255
++ A + ++ G T L + +++L
Sbjct: 425 ENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 456
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Query: 88 VCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACF 147
V L E + D + T L+ A GH +++ L+K GA V+ + + L A
Sbjct: 321 VKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAAL 380
Query: 148 EGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
G D+ + L+ + + + + T L AAY GY++ + L+++ A + + G TA
Sbjct: 381 GGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTA 440
Query: 208 LHFAAECGHAAVVCSLLDHGA---KMLTNENGMTPLQCAAERARASVVEIL 255
LH++ G+ + LLD A +M NE TPL A R V++ +
Sbjct: 441 LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 491
Score = 38.7 bits (86), Expect = 0.065
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 3/156 (1%)
Query: 115 AGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTC 174
A L L+KAGADVN + T L A +G +K L+ A+ + + T
Sbjct: 6 ADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTP 65
Query: 175 LMIAAYKGYLDVVQFLLD--SGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-L 231
L + + LL + VD + TALH++A + V L+ H + + +
Sbjct: 66 LHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGI 125
Query: 232 TNENGMTPLQCAAERARASVVEILAARPEVTRAEAI 267
+ G PL AA S V + + E++
Sbjct: 126 PDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESL 161
Score = 36.3 bits (80), Expect = 0.35
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 206 TALHFAAECGHAAVVCSLLDHGAK--MLTNENGMTPLQCAAERARASVVEILAARPEV 261
T LH+AA GHA +V LL+ + ++ G TPL AA+ A V++ P V
Sbjct: 205 TPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV 262
Score = 34.3 bits (75), Expect = 1.4
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHG 161
EG TAL + G+L +K L+ A N TPL A R +++++++ HG
Sbjct: 436 EGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 495
Query: 162 ADIHKANKYNNTCLMIAAYKGY 183
A A + + A YKGY
Sbjct: 496 ALSIAAIQDIAAFKIQAVYKGY 517
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 149 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 197
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 198 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 257
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 258 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 316
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 317 TDVNIKDNHGLTALDTVRE 335
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 116 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 175
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 176 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 235
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 236 ALYGRLEVVKML 247
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 126 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 185
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 186 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 245
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 246 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 280
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 121 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 169
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 170 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 229
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 230 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 289
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 290 QTEMGSALHEAALFGKTDVVQILLA 314
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 103 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 151
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 152 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 211
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 212 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 270
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 271 TDVNIKDNHGLTALDTVRE 289
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 190 ALYGRLEVVKML 201
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 200 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 234
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 75 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 123
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 124 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 183
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 243
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 244 QTEMGSALHEAALFGKTDVVQILLA 268
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 103 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 151
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 152 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 211
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 212 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 270
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 271 TDVNIKDNHGLTALDTVRE 289
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 190 ALYGRLEVVKML 201
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 200 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 234
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 75 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 123
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 124 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 183
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 243
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 244 QTEMGSALHEAALFGKTDVVQILLA 268
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 103 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 151
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 152 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 211
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 212 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 270
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 271 TDVNIKDNHGLTALDTVRE 289
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 190 ALYGRLEVVKML 201
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 200 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 234
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 75 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 123
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 124 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 183
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 243
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 244 QTEMGSALHEAALFGKTDVVQILLA 268
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 103 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 151
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 152 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 211
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 212 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 270
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 271 TDVNIKDNHGLTALDTVRE 289
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 190 ALYGRLEVVKML 201
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 200 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 234
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 75 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 123
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 124 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 183
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 243
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 244 QTEMGSALHEAALFGKTDVVQILLA 268
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 76.6 bits (180), Expect = 3e-13
Identities = 65/199 (32%), Positives = 92/199 (46%), Gaps = 13/199 (6%)
Query: 48 DDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGAT 107
D L N+ +D C PL AA G VR+L+ + + +E + T
Sbjct: 103 DALTNV---ADSKGCYPLHLAAWKGDAQIVRLLIH--------QGPSHTRVNEQNNDNET 151
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
AL CA+ GH +VK L++ D TPL A GRL++VK L+ ++
Sbjct: 152 ALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSC 211
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
N +T L +AA G+ VVQ LLD+G + + G +ALH AA G VV LL G
Sbjct: 212 NTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMG-SALHEAALFGKTDVVQILLAAG 270
Query: 228 AKMLTNEN-GMTPLQCAAE 245
+ +N G+T L E
Sbjct: 271 TDVNIKDNHGLTALDTVRE 289
Score = 65.3 bits (152), Expect = 7e-10
Identities = 47/132 (35%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Query: 128 GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
G +VN T TPL A G D+V+ L+R+ A + A+ L +AA+KG +V
Sbjct: 70 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 129
Query: 188 QFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLDH-GAKMLTNENGMTPLQCA 243
+ L+ G RV+++ TALH AA+ GH VV LL+ + N TPL A
Sbjct: 130 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLA 189
Query: 244 AERARASVVEIL 255
A R VV++L
Sbjct: 190 ALYGRLEVVKML 201
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A+ GH +V+ L++ A N A PL A ++G IV+ L+ G
Sbjct: 80 GYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSH 139
Query: 165 HKANKYNN---TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
+ N+ NN T L AA G+ +VV+ LL+ R T L AA G VV
Sbjct: 140 TRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVK 199
Query: 222 SLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
LL+ +L+ N TPL AA +VV++L
Sbjct: 200 MLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 234
Score = 60.5 bits (140), Expect = 2e-08
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 14/205 (6%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA +G + V +LL +++G L A+
Sbjct: 75 CVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYP-----------LHLAAWK 123
Query: 116 GHLAIVKRLVKAGAD---VNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN 172
G IV+ L+ G VN T L A G ++VK L+ D N
Sbjct: 124 GDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFE 183
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L +AA G L+VV+ LL++ + T LH AA GH AVV LLD G
Sbjct: 184 TPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNY 243
Query: 233 NENGMTPLQCAAERARASVVEILAA 257
+ L AA + VV+IL A
Sbjct: 244 QTEMGSALHEAALFGKTDVVQILLA 268
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 76.6 bits (180), Expect = 3e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQDNAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQDNAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens
cDNA FLJ10421 fis, clone NT2RP1000202, weakly similar to
ANKYRIN. ).
Length = 445
Score = 76.6 bits (180), Expect = 3e-13
Identities = 49/154 (31%), Positives = 83/154 (53%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG AL A+ GH IV+ L++AGAD N T +TPL +A G++D+++ L++HGA+
Sbjct: 5 EGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGAN 64
Query: 164 IHKANKYNN-TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ ++ L A+++ ++++ LL GA + + G T L AA+ G +
Sbjct: 65 VNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSI 124
Query: 223 LLDHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
L+ GA + + TPL AA+ VE+L
Sbjct: 125 LISSGANVNCQALDKATPLFIAAQEGHTKCVELL 158
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 37 LEETTPLFSAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 96
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 97 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 156
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 157 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 193
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 17/198 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL +A +G+ +R+LL+ G + + G +L AS + I+K
Sbjct: 41 TPLFSAVENGQIDVLRLLLQ----------HGANVNGSHSMCGWNSLHQASFQENAEIIK 90
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA+ TPL A G+L+ + L+ GA+++ T L IAA +G
Sbjct: 91 LLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEG 150
Query: 183 YLDVVQFLLDSGARVDDRALCGATA----LHFAAECGHAAVVCSLLDHGAKML-TNENGM 237
+ V+ LL SGA D C + +H AA+ GH ++ L+ + T N +
Sbjct: 151 HTKCVELLLSSGA--DPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKV 208
Query: 238 TPLQCAAERARASVVEIL 255
+P+ A +EIL
Sbjct: 209 SPVYSAVFGGHEDCLEIL 226
Score = 41.9 bits (94), Expect = 0.007
Identities = 44/182 (24%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA++G+ ++ IL+ C ++ AT L+ A+
Sbjct: 101 CQDDFGITPLFVAAQYGKLESLSILISSGANVNC-----------QALDKATPLFIAAQE 149
Query: 116 GHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
GH V+ L+ +GAD + S P+ AA G I+ L+ +
Sbjct: 150 GHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVS 209
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRA-----LCGATALHFAAECGHAAVVCSLLDHGA 228
+ A + G+ D ++ LL +G D +A + F +C +V LL +GA
Sbjct: 210 PVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVNILLKYGA 269
Query: 229 KM 230
++
Sbjct: 270 QI 271
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 38 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 88
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 89 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 140
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 141 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 200
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 201 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 260
Query: 250 SVVEIL 255
VE+L
Sbjct: 261 KCVELL 266
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 145 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 204
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 205 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 264
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 265 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 301
Score = 46.4 bits (105), Expect = 3e-04
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 5/137 (3%)
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
RLVK D A + + A EG + +++ L++ G + A+ + AAY
Sbjct: 31 RLVKQ-MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHN 89
Query: 183 YLDVVQFLLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMT 238
++ +Q L+++ + + + G ALH AA GH +V LL+ GA T T
Sbjct: 90 SVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETT 149
Query: 239 PLQCAAERARASVVEIL 255
PL A E + V+ +L
Sbjct: 150 PLFLAVENGQIDVLRLL 166
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 235 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 295 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 354
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 355 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 388
Score = 64.9 bits (151), Expect = 9e-10
Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GAD+ +
Sbjct: 175 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADVQQVGYG 234
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 235 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 295 NVSGEVGDRPLHLASAKGFLNIAKLL 320
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 260 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 307
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 308 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 367
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 368 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 427
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 428 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 483
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 484 QTCLMWAYEKGHDAI 498
Score = 60.5 bits (140), Expect = 2e-08
Identities = 41/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GADV T L A G L+ L++HGA++
Sbjct: 202 GFTALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 261
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 262 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 321
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 322 EEGSKADVN 330
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 391 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 450
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 451 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 509
Query: 199 DRALC 203
D C
Sbjct: 510 DELPC 514
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase 2
protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 691 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 750
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 751 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 810
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 811 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 870
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 871 TLKNQEGQTPL 881
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 598 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 657
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 658 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 717
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 718 TKKNRDGNTPL 728
Score = 62.9 bits (146), Expect = 3e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 119 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAXFGRKDVVEYLL 178
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 179 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 238
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 239 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 270
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 221 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 280
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 281 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 340
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 341 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 400
Query: 228 A 228
A
Sbjct: 401 A 401
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 465 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 524
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 525 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 574
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 621 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 680
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 681 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 728
Score = 55.6 bits (128), Expect = 5e-07
Identities = 43/143 (30%), Positives = 69/143 (48%), Gaps = 4/143 (2%)
Query: 131 VNHATRTVSTPLRAAC---FEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVV 187
V A++T T L A + R I + L+R GA+I++ K T L +A+ K + DVV
Sbjct: 456 VIQASQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVV 515
Query: 188 QFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAER 246
+ ++ A+V+ G T+LH AA CGH LL +G + + G T LQ E
Sbjct: 516 EVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 575
Query: 247 ARASVVEILAARPEVTRAEAIEA 269
+ + E ++ + +EA
Sbjct: 576 VQQLLQEGISLGNSEADRQLLEA 598
Score = 52.8 bits (121), Expect = 4e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 156 GRKSTPLHFAAXFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 204
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 205 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 264
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 265 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 324
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 325 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 384
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 385 ASKNRVEVCSLLLSY 399
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 300 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 348
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 349 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 408
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 409 HNKSAIDLA 417
Score = 46.4 bits (105), Expect = 3e-04
Identities = 52/184 (28%), Positives = 80/184 (43%), Gaps = 11/184 (5%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T+L A+ GHL + L+ G D N + T L+ + V+ L++ G I
Sbjct: 532 GQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMG-----NENVQQLLQEG--I 584
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCS 222
N + L+ AA G ++ V+ L + V+ R + G +T LHFAA +VV
Sbjct: 585 SLGNSEADRQLLEAAKAGDVETVKKLC-TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEY 643
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDK 281
LL HGA + ++ G+ PL A V E+L V + + L + A K
Sbjct: 644 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGK 703
Query: 282 EYYC 285
C
Sbjct: 704 YEIC 707
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/191 (31%), Positives = 87/191 (45%), Gaps = 11/191 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 592 KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD 651
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA VK+L + STPL A L++ +YL++HGAD++ +K
Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++DV L+ A V+ T LH AA+ G + LL HGA
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 771
Query: 230 MLTNENGMTPL 240
L N+ G TPL
Sbjct: 772 TLKNQEGQTPL 782
Score = 65.7 bits (153), Expect = 5e-10
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ AG + VK+L + STPL A R+ +V+YL++HGAD+H +K
Sbjct: 499 AAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADP 618
Query: 230 MLTNENGMTPL 240
N +G TPL
Sbjct: 619 TKKNRDGNTPL 629
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/106 (38%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G G +V+ L++ GA+V PL AC G ++V L+RHGAD +
Sbjct: 59 STPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA R G TAL A
Sbjct: 119 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 62.1 bits (144), Expect = 6e-09
Identities = 54/152 (35%), Positives = 72/152 (47%), Gaps = 2/152 (1%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLV 158
E V A L+ A G + VKRLV + T STPL A GR D+V+YL+
Sbjct: 19 EAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLL 78
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
++GA++ + L A G+ +VV LL GA + R T LH AA G
Sbjct: 79 QNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKID 138
Query: 219 VVCSLLDHGAK-MLTNENGMTPLQCAAERARA 249
V LL HGA+ + N +G T L A A+A
Sbjct: 139 VCIVLLQHGAEPTIRNTDGRTALDLADPSAKA 170
Score = 58.4 bits (135), Expect = 8e-08
Identities = 52/181 (28%), Positives = 76/181 (41%), Gaps = 10/181 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDE 180
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 181 LLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAK 240
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K + L A G+ +V + L+ GA V+ L T LH AA V LL +G
Sbjct: 241 DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYG 300
Query: 228 A 228
A
Sbjct: 301 A 301
Score = 58.4 bits (135), Expect = 8e-08
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA+ + + I + L++ GA++N T+ TPL A + D+V+ +V+H A
Sbjct: 366 TALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAK 425
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AAY G+L + LL G + +L G TAL E
Sbjct: 426 VNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE 475
Score = 58.4 bits (135), Expect = 8e-08
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 103 IEG--ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH 160
IEG +T L A+G +++V+ L++ GADV+ + PL AC G ++ + LV+H
Sbjct: 522 IEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKH 581
Query: 161 GADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
GA ++ A+ + T L AA KG ++ + LL GA + G T L
Sbjct: 582 GAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPL 629
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/173 (28%), Positives = 78/173 (45%), Gaps = 5/173 (2%)
Query: 101 YVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAAC---FEGRLDIVKYL 157
Y +G + L A A I K L + H +T T L A + R I + L
Sbjct: 328 YEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHP-QTHETALHCAAASPYPKRKQICELL 386
Query: 158 VRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHA 217
+R GA+I++ K T L +A+ K + DVV+ ++ A+V+ G T+LH AA CGH
Sbjct: 387 LRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHL 446
Query: 218 AVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEA 269
LL +G + + G T LQ E + + E ++ + +EA
Sbjct: 447 QTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499
Score = 52.4 bits (120), Expect = 5e-06
Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 34/255 (13%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K TPL AA GR+ V LL+ V +G G L A GH
Sbjct: 56 GRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDG----------GLIPLHNACSFGHA 104
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIA 178
+V L++ GAD N TPL A +G++D+ L++HGA+ N T L +A
Sbjct: 105 EVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Query: 179 --AYKGYLD---VVQFLLDSGARVDDRAL----------CGA------TALHFAAECGHA 217
+ K L LL+S ++ + C A T LH AA
Sbjct: 165 DPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 224
Query: 218 AVVCSLLDHGAKMLTNENG-MTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGAS 276
+V LL HGA + + G + PL A V E+L A + + L +
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 277 FANDKEYYC-LRMAY 290
+ ++ C L ++Y
Sbjct: 285 ASKNRVEVCSLLLSY 299
Score = 46.4 bits (105), Expect = 3e-04
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 12/129 (9%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G + L
Sbjct: 200 LNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDL----------VPL 248
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + LVK GA VN TPL A + R+++ L+ +GAD N
Sbjct: 249 HNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNC 308
Query: 170 YNNTCLMIA 178
+N + + +A
Sbjct: 309 HNKSAIDLA 317
Score = 38.3 bits (85), Expect = 0.086
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
+E E T L AS H +V+ +VK A VN T L A + G L + L+
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLL 453
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+G D + + T L + + ++Q + G DR L A A +
Sbjct: 454 SYGCDPNIISLQGFTALQMGN-ENVQQLLQEGISLGNSEADRQLLEAAK---AGDVETVK 509
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
+C++ + + TPL AA R SVVE L
Sbjct: 510 KLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYL 545
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 253
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 254 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 287
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 74 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 133
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 134 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 159 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 206
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 207 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 266
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 267 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 326
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 327 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 382
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 383 QTCLMWAYEKGHDAI 397
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 101 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 160
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 161 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 221 EEGSKADVN 229
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 290 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 349
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 350 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 408
Query: 199 DRALC 203
D C
Sbjct: 409 DELPC 413
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 3 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 53
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 54 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 105
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 106 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 166 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 225
Query: 250 SVVEIL 255
VE+L
Sbjct: 226 KCVELL 231
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 110 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 169
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 170 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 229
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 230 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266
Score = 44.4 bits (100), Expect = 0.001
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 4/130 (3%)
Query: 130 DVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQF 189
D A + + A EG + +++ L++ G + A+ + AAY ++ +Q
Sbjct: 2 DFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQM 61
Query: 190 LLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAE 245
L+++ + + + G ALH AA GH +V LL+ GA T TPL A E
Sbjct: 62 LINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVE 121
Query: 246 RARASVVEIL 255
+ V+ +L
Sbjct: 122 NGQIDVLRLL 131
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 76.2 bits (179), Expect = 4e-13
Identities = 70/246 (28%), Positives = 114/246 (46%), Gaps = 19/246 (7%)
Query: 12 FNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNIDVCSDGVKCTPLITAARH 71
F E V AAR+G L LL KK +D +D P+ AA H
Sbjct: 13 FTEAYADTCSTVGLAAREGNVKVLRKLL--KKGRSVD-------VADNRGWMPIHEAAYH 63
Query: 72 GREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADV 131
+++L+ +E +K + EG AL A+ GH IV+ L++AGAD
Sbjct: 64 NSVECLQMLINAD------SSENYIKMKTF--EGFCALHLAASQGHWKIVQILLEAGADP 115
Query: 132 NHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-TCLMIAAYKGYLDVVQFL 190
N T +TPL A G++D+++ L++HGA+++ ++ L A+++ ++++ L
Sbjct: 116 NATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 175
Query: 191 LDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARA 249
L GA + + G T L AA+ G + L+ GA + + TPL AA+
Sbjct: 176 LRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHT 235
Query: 250 SVVEIL 255
VE+L
Sbjct: 236 KCVELL 241
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 120 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 179
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 180 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 239
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 240 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 276
Score = 46.4 bits (105), Expect = 3e-04
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 5/137 (3%)
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
RLVK D A + + A EG + +++ L++ G + A+ + AAY
Sbjct: 6 RLVKQ-MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHN 64
Query: 183 YLDVVQFLLDSGAR---VDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLTNENGMT 238
++ +Q L+++ + + + G ALH AA GH +V LL+ GA T T
Sbjct: 65 SVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETT 124
Query: 239 PLQCAAERARASVVEIL 255
PL A E + V+ +L
Sbjct: 125 PLFLAVENGQIDVLRLL 141
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 76.2 bits (179), Expect = 4e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 240 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 299
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 300 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKY 359
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 360 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 393
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 180 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 239
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 240 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 299
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 300 NVSGEVGDRPLHLASAKGFLNIAKLL 325
Score = 63.7 bits (148), Expect = 2e-09
Identities = 76/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 265 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 312
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G DIVKYL++ ++ H
Sbjct: 313 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVV 372
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 373 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 432
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 433 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDP----SRSSGEKDE 488
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 489 QTCLMWAYEKGHDAI 503
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 207 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 266
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 267 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 326
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 327 EEGSKADVN 335
Score = 44.8 bits (101), Expect = 0.001
Identities = 37/125 (29%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 396 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 455
Query: 148 EGRLDIVKYLVRHGADIH---------KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD++ K TCLM A KG+ D + LL R
Sbjct: 456 HGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 514
Query: 199 DRALC 203
D C
Sbjct: 515 DELPC 519
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 75.8 bits (178), Expect = 5e-13
Identities = 49/154 (31%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
EG AL A+ GH IV+ L++AGAD N T +TPL A G++D+++ L++HGA+
Sbjct: 72 EGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGAN 131
Query: 164 IHKANKYNN-TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ ++ L A+++ ++++ LL GA + + G T L AA+ G +
Sbjct: 132 VNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSI 191
Query: 223 LLDHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
L+ GA + + TPL AA+ VE+L
Sbjct: 192 LISSGANVNCQALDKATPLFIAAQEGHTKCVELL 225
Score = 74.1 bits (174), Expect = 1e-12
Identities = 50/157 (31%), Positives = 82/157 (52%), Gaps = 4/157 (2%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHG 161
+E T L+ A G + +++ L++ GA+VN + L A F+ +I+K L+R G
Sbjct: 104 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 163
Query: 162 ADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
A+ + + T L +AA G L+ + L+ SGA V+ +AL AT L AA+ GH V
Sbjct: 164 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 223
Query: 222 SLLDHGA--KMLTNENG-MTPLQCAAERARASVVEIL 255
LL GA + NE+ P+ AA+ ++++L
Sbjct: 224 LLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 260
Score = 53.6 bits (123), Expect = 2e-06
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
TPL A +G+ +R+LL+ G + + G +L AS + I+K
Sbjct: 108 TPLFLAVENGQIDVLRLLLQ----------HGANVNGSHSMCGWNSLHQASFQENAEIIK 157
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKG 182
L++ GA+ TPL A G+L+ + L+ GA+++ T L IAA +G
Sbjct: 158 LLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEG 217
Query: 183 YLDVVQFLLDSGARVDDRALCGATA----LHFAAECGHAAVVCSLLDHGAKML-TNENGM 237
+ V+ LL SGA D C + +H AA+ GH ++ L+ + T N +
Sbjct: 218 HTKCVELLLSSGA--DPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKV 275
Query: 238 TPLQCAAERARASVVEIL 255
+P+ A +EIL
Sbjct: 276 SPVYSAVFGGHEDCLEIL 293
Score = 41.9 bits (94), Expect = 0.007
Identities = 44/182 (24%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 56 CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGA 115
C D TPL AA++G+ ++ IL+ C ++ AT L+ A+
Sbjct: 168 CQDDFGITPLFVAAQYGKLESLSILISSGANVNC-----------QALDKATPLFIAAQE 216
Query: 116 GHLAIVKRLVKAGADVNHATRTVS--TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
GH V+ L+ +GAD + S P+ AA G I+ L+ +
Sbjct: 217 GHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVS 276
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRA-----LCGATALHFAAECGHAAVVCSLLDHGA 228
+ A + G+ D ++ LL +G D +A + F +C +V LL +GA
Sbjct: 277 PVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVNILLKYGA 336
Query: 229 KM 230
++
Sbjct: 337 QI 338
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 75.4 bits (177), Expect = 6e-13
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL L++ GA+VN TPL A + G + + L++ GAD+
Sbjct: 252 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 311
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + + + L +A+ KG+L++ + L++ G++ D A LHF + GH +V
Sbjct: 312 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKY 371
Query: 223 LLDHGAKM---LTNENGMTPLQCAAERARASVVE 253
LL ++ + N G TPL A + V +
Sbjct: 372 LLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAK 405
Score = 65.3 bits (152), Expect = 7e-10
Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Query: 111 CASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
C G + ++ L+ G + TR T L A ++ +++ L+ GADI +
Sbjct: 192 CCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG 251
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM 230
T L IA G+L+ LL GA V+ + T LH AA GH V LL GA +
Sbjct: 252 GLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 311
Query: 231 -LTNENGMTPLQCAAERARASVVEIL 255
++ E G PL A+ + ++ ++L
Sbjct: 312 NVSGEVGDRPLHLASAKGFLNIAKLL 337
Score = 62.1 bits (144), Expect = 6e-09
Identities = 75/255 (29%), Positives = 106/255 (41%), Gaps = 25/255 (9%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+++ D V TPL AA +G E R+LL KF V G V G L
Sbjct: 277 NVNI-QDAVFFTPLHIAAYYGHEQVTRLLL-KFGADV--NVSGEV--------GDRPLHL 324
Query: 112 ASGAGHLAIVKRLVKAG--ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI--HKA 167
AS G L I K L++ G ADVN PL G D+VKYL++ ++ H
Sbjct: 325 ASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQPHVV 384
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLD-SGAR-VDDRALCGATALHFAAECGHAA-VVCSLL 224
N Y +T L +A Y G +V + ++ SG + + TA H A G + +V LL
Sbjct: 385 NIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLL 444
Query: 225 DHGAKMLTNE--NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKE 282
D + ++ +G T L A +V+ L A + S E
Sbjct: 445 DQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMSLVACDP----SRSSGEKDE 500
Query: 283 YYCLRMAYQYLHRAM 297
CL AY+ H A+
Sbjct: 501 QTCLMWAYEKGHDAI 515
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/129 (31%), Positives = 61/129 (47%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A + ++ L+ +GAD+ T L A G L+ L++HGA++
Sbjct: 219 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 278
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLL 224
+ + T L IAAY G+ V + LL GA V+ G LH A+ G + L+
Sbjct: 279 NIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 338
Query: 225 DHGAKMLTN 233
+ G+K N
Sbjct: 339 EEGSKADVN 347
Score = 44.0 bits (99), Expect = 0.002
Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 90 LETEGTVKFDEYVIEGATALWCASGAGH-LAIVKRLVKAGA-DVNHATRTVSTPLRAACF 147
++ GT + I TA A G + +VK L+ ++NH R T L +AC+
Sbjct: 408 IQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACY 467
Query: 148 EGRLDIVKYLVRHGADI---------HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVD 198
G + +V++L+ +GAD+ K TCLM A KG+ D + LL R
Sbjct: 468 HGHIRLVQFLLDNGADMSLVACDPSRSSGEKDEQTCLMWAYEKGH-DAIVTLLKHYKRPQ 526
Query: 199 DRALC 203
D C
Sbjct: 527 DELPC 531
>AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 74.9 bits (176), Expect = 8e-13
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G T L A+ G + +L++ ADVN T + GR +++ LV+H +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + T L +A VQ LLDSGA ++ + GAT L+FA G
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 223 LLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL GAK L ++NG+TPL + E+L
Sbjct: 210 LLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVL 242
Score = 57.2 bits (132), Expect = 2e-07
Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 7/151 (4%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ G + + L+K GA+ N+ + TPL A G+ + L+ + AD++ N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
T + A G +++ L+ + VD G TALH A V C LLD GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA-----CTVQC-LLDSGA 182
Query: 229 KM-LTNENGMTPLQCAAERARASVVEILAAR 258
+ N +G TPL A + +IL R
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLR 213
Score = 47.2 bits (107), Expect = 2e-04
Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 20/200 (10%)
Query: 62 CTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIV 121
CTPL AAR+G++ + LLE + V + EG TA+ + G ++
Sbjct: 99 CTPLHLAARNGQKKCMSKLLE-YSADVNICNN----------EGLTAIHWLAVNGRTELL 147
Query: 122 KRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
LV+ +DV+ T L AC V+ L+ GADI++ N T L A
Sbjct: 148 HDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSH 201
Query: 182 GYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPL 240
G D Q LL GA+ + D+ G T L + G+ L+ + ++ MT
Sbjct: 202 GQRDTAQILLLRGAKYLPDKN--GVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQN 259
Query: 241 QCAAERARASVVEILAARPE 260
+ E V+E L+ + E
Sbjct: 260 EDLRENMLRQVLEHLSQQSE 279
Score = 41.1 bits (92), Expect = 0.012
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 163 DIHKA-NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D++ A + + L IAA G ++ + LL GA + + + G T LH AA G +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMS 115
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL++ A + + N G+T + A R ++ L
Sbjct: 116 KLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDL 150
>AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 74.9 bits (176), Expect = 8e-13
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G T L A+ G + +L++ ADVN T + GR +++ LV+H +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + T L +A VQ LLDSGA ++ + GAT L+FA G
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 223 LLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL GAK L ++NG+TPL + E+L
Sbjct: 210 LLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVL 242
Score = 57.2 bits (132), Expect = 2e-07
Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 7/151 (4%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ G + + L+K GA+ N+ + TPL A G+ + L+ + AD++ N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
T + A G +++ L+ + VD G TALH A V C LLD GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA-----CTVQC-LLDSGA 182
Query: 229 KM-LTNENGMTPLQCAAERARASVVEILAAR 258
+ N +G TPL A + +IL R
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLR 213
Score = 47.2 bits (107), Expect = 2e-04
Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 20/200 (10%)
Query: 62 CTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIV 121
CTPL AAR+G++ + LLE + V + EG TA+ + G ++
Sbjct: 99 CTPLHLAARNGQKKCMSKLLE-YSADVNICNN----------EGLTAIHWLAVNGRTELL 147
Query: 122 KRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
LV+ +DV+ T L AC V+ L+ GADI++ N T L A
Sbjct: 148 HDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSH 201
Query: 182 GYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPL 240
G D Q LL GA+ + D+ G T L + G+ L+ + ++ MT
Sbjct: 202 GQRDTAQILLLRGAKYLPDKN--GVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQN 259
Query: 241 QCAAERARASVVEILAARPE 260
+ E V+E L+ + E
Sbjct: 260 EDLRENMLRQVLEHLSQQSE 279
Score = 41.1 bits (92), Expect = 0.012
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 163 DIHKA-NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D++ A + + L IAA G ++ + LL GA + + + G T LH AA G +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMS 115
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL++ A + + N G+T + A R ++ L
Sbjct: 116 KLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDL 150
>AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 74.9 bits (176), Expect = 8e-13
Identities = 49/153 (32%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I G T L A+ G + +L++ ADVN T + GR +++ LV+H +
Sbjct: 96 ISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVS 155
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + T L +A VQ LLDSGA ++ + GAT L+FA G
Sbjct: 156 DVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQI 209
Query: 223 LLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
LL GAK L ++NG+TPL + E+L
Sbjct: 210 LLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVL 242
Score = 57.2 bits (132), Expect = 2e-07
Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 7/151 (4%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN 168
L A+ G + + L+K GA+ N+ + TPL A G+ + L+ + AD++ N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
T + A G +++ L+ + VD G TALH A V C LLD GA
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVA-----CTVQC-LLDSGA 182
Query: 229 KM-LTNENGMTPLQCAAERARASVVEILAAR 258
+ N +G TPL A + +IL R
Sbjct: 183 DINRPNVSGATPLYFACSHGQRDTAQILLLR 213
Score = 47.2 bits (107), Expect = 2e-04
Identities = 55/200 (27%), Positives = 85/200 (42%), Gaps = 20/200 (10%)
Query: 62 CTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIV 121
CTPL AAR+G++ + LLE + V + EG TA+ + G ++
Sbjct: 99 CTPLHLAARNGQKKCMSKLLE-YSADVNICNN----------EGLTAIHWLAVNGRTELL 147
Query: 122 KRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK 181
LV+ +DV+ T L AC V+ L+ GADI++ N T L A
Sbjct: 148 HDLVQHVSDVDVEDAMGQTALHVAC------TVQCLLDSGADINRPNVSGATPLYFACSH 201
Query: 182 GYLDVVQFLLDSGAR-VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPL 240
G D Q LL GA+ + D+ G T L + G+ L+ + ++ MT
Sbjct: 202 GQRDTAQILLLRGAKYLPDKN--GVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQN 259
Query: 241 QCAAERARASVVEILAARPE 260
+ E V+E L+ + E
Sbjct: 260 EDLRENMLRQVLEHLSQQSE 279
Score = 41.1 bits (92), Expect = 0.012
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 163 DIHKA-NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVC 221
D++ A + + L IAA G ++ + LL GA + + + G T LH AA G +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMS 115
Query: 222 SLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL++ A + + N G+T + A R ++ L
Sbjct: 116 KLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDL 150
>AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1094
Score = 74.9 bits (176), Expect = 8e-13
Identities = 61/207 (29%), Positives = 95/207 (45%), Gaps = 12/207 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + +++G AL
Sbjct: 517 KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLD 576
Query: 112 ASGAGHLAIVKRL-VKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA V++L + STPL A L++ +YL+ HGAD++ +K
Sbjct: 577 AAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG 636
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++D+ L+ V+ T LH AA+ G + LL HGA
Sbjct: 637 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 696
Query: 230 MLTNENGMTPLQCA-AERARASVVEIL 255
+ N+ G TPL A A+ RA +++ +
Sbjct: 697 TMKNQEGQTPLDLATADDIRALLIDAM 723
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/136 (36%), Positives = 65/136 (47%), Gaps = 2/136 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
AS AG L VK+L + + STPL A R+ +V+YL+ HGAD+H +K
Sbjct: 424 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 483
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 484 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 543
Query: 230 MLTNENGMTPLQCAAE 245
N +G TPL E
Sbjct: 544 TKKNRDGNTPLDLVKE 559
Score = 61.3 bits (142), Expect = 1e-08
Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 11/197 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 46 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDE 105
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 106 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 165
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K L A G+ +V + LL GA V+ L T LH AA V LL HG
Sbjct: 166 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 225
Query: 228 A-KMLTNENGMTPLQCA 243
A L N +G + + A
Sbjct: 226 ADPTLVNCHGKSAVDMA 242
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/173 (31%), Positives = 74/173 (42%), Gaps = 22/173 (12%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A GH + + LV+ GA VN A TPL A +G+ +I K L++HGAD
Sbjct: 484 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 543
Query: 165 HKANKYNNT--------------------CLMIAAYKGYLDVVQFL-LDSGARVDDRALC 203
K N+ NT L+ AA KG L VQ L D
Sbjct: 544 TKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 603
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+T LH AA + V LL+HGA + ++ G+ PL AA + +L
Sbjct: 604 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 656
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/108 (33%), Positives = 56/108 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G +++V+ L+ GADV+ + PL AC G ++ + LVRHGA ++
Sbjct: 452 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 511
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
A+ + T L AA KG ++ + LL GA + G T L E
Sbjct: 512 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 559
Score = 57.6 bits (133), Expect = 1e-07
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 7/134 (5%)
Query: 150 RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALH 209
R + + L+R GA++++ NK T L +AA + + DV++ L GA+++ G TALH
Sbjct: 304 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 363
Query: 210 FAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIE 268
AA GH LL +G+ + + G T AA+ +V +IL+ + ++
Sbjct: 364 RAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTPIRTSDV-- 417
Query: 269 AYELLGASFANDKE 282
Y LL AS A D E
Sbjct: 418 DYRLLEASKAGDLE 431
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA + H + + L++ GA+VN + TPL A D+++ L +HGA
Sbjct: 291 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 350
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AA G+L + LL G+ +L G TA E
Sbjct: 351 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNE 400
Score = 50.8 bits (116), Expect = 2e-05
Identities = 68/232 (29%), Positives = 100/232 (43%), Gaps = 39/232 (16%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G G L
Sbjct: 125 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKG----------GLVPL 173
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + L+K GA VN TPL A + R+++ L+ HGAD N
Sbjct: 174 HNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNC 233
Query: 170 YNNTCLMIA-----------AYKGYLDVVQFLLDSGARVDDRALC-----------GATA 207
+ + + +A +KG+ ++Q ++ + L TA
Sbjct: 234 HGKSAVDMAPTPELRERLTYEFKGH-SLLQAAREADLAKVKKTLALEIINFKQPQSHETA 292
Query: 208 LHFAAECGH---AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH A H V LL GA + N++ MTPL AAERA V+E+L
Sbjct: 293 LHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 344
Score = 50.0 bits (114), Expect = 3e-05
Identities = 51/174 (29%), Positives = 73/174 (41%), Gaps = 24/174 (13%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A GH +V L+ GAD N TPL A +G++D+ L++HGAD
Sbjct: 16 GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 75
Query: 165 HKAN--------------------KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
+ N +Y L+ AA G + + LL + V+ A G
Sbjct: 76 NIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALL-TPLNVNCHASDG 134
Query: 205 --ATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+T LH AA +V LL HGA + ++ G+ PL A V E+L
Sbjct: 135 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL 188
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/88 (36%), Positives = 45/88 (51%)
Query: 124 LVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGY 183
L++ GA+V+ PL AC G ++V L+ GAD + + +N T L AA KG
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK 61
Query: 184 LDVVQFLLDSGARVDDRALCGATALHFA 211
+DV LL GA + R G +AL A
Sbjct: 62 IDVCIVLLQHGADPNIRNTDGKSALDLA 89
Score = 43.6 bits (98), Expect = 0.002
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 11/154 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL + L+ G+D + +S A G + V+ ++ I
Sbjct: 358 GQTALHRAALAGHLQTCRLLLSYGSDPS----IISLQGFTAAQMGN-EAVQQILSESTPI 412
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCS 222
++ + L+ A+ G L+ V+ L S V+ R L G +T LHFAA +VV
Sbjct: 413 RTSDV--DYRLLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEY 469
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL HGA + ++ G+ PL A V E+L
Sbjct: 470 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 503
Score = 40.7 bits (91), Expect = 0.016
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 156 YLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECG 215
+L++ GA++H + L A G+ +VV LL GA + R T LH AA G
Sbjct: 1 HLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKG 60
Query: 216 HAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARA 249
V LL HGA + N +G + L A A+A
Sbjct: 61 KIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKA 95
Score = 37.5 bits (83), Expect = 0.15
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
C + + + V + LL GA V+++ T LH AAE H V+ L HGAKM
Sbjct: 295 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNAL 354
Query: 234 EN-GMTPLQCAA 244
+ G T L AA
Sbjct: 355 DTLGQTALHRAA 366
>AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 74.9 bits (176), Expect = 8e-13
Identities = 61/207 (29%), Positives = 95/207 (45%), Gaps = 12/207 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + +++G AL
Sbjct: 750 KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLD 809
Query: 112 ASGAGHLAIVKRL-VKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA V++L + STPL A L++ +YL+ HGAD++ +K
Sbjct: 810 AAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG 869
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++D+ L+ V+ T LH AA+ G + LL HGA
Sbjct: 870 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 929
Query: 230 MLTNENGMTPLQCA-AERARASVVEIL 255
+ N+ G TPL A A+ RA +++ +
Sbjct: 930 TMKNQEGQTPLDLATADDIRALLIDAM 956
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/136 (36%), Positives = 65/136 (47%), Gaps = 2/136 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
AS AG L VK+L + + STPL A R+ +V+YL+ HGAD+H +K
Sbjct: 657 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 716
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 230 MLTNENGMTPLQCAAE 245
N +G TPL E
Sbjct: 777 TKKNRDGNTPLDLVKE 792
Score = 61.3 bits (142), Expect = 1e-08
Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 11/197 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 279 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDE 338
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 339 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 398
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K L A G+ +V + LL GA V+ L T LH AA V LL HG
Sbjct: 399 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 458
Query: 228 A-KMLTNENGMTPLQCA 243
A L N +G + + A
Sbjct: 459 ADPTLVNCHGKSAVDMA 475
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/173 (31%), Positives = 74/173 (42%), Gaps = 22/173 (12%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A GH + + LV+ GA VN A TPL A +G+ +I K L++HGAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 165 HKANKYNNT--------------------CLMIAAYKGYLDVVQFL-LDSGARVDDRALC 203
K N+ NT L+ AA KG L VQ L D
Sbjct: 777 TKKNRDGNTPLDLVKEGDTDIQDLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 836
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+T LH AA + V LL+HGA + ++ G+ PL AA + +L
Sbjct: 837 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Query: 116 GHLAIVKRLVKAGADVNHATRT--VSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G ++ VKRLV A A+VN S+PL A GR D+V++L++ GA++H +
Sbjct: 193 GDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLI 251
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLT 232
L A G+ +VV LL GA + R T LH AA G V LL HGA +
Sbjct: 252 PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
Query: 233 NENGMTPLQCAAERARA 249
N +G + L A A+A
Sbjct: 312 NTDGKSALDLADPSAKA 328
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/108 (33%), Positives = 56/108 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G +++V+ L+ GADV+ + PL AC G ++ + LVRHGA ++
Sbjct: 685 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
A+ + T L AA KG ++ + LL GA + G T L E
Sbjct: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 792
Score = 57.6 bits (133), Expect = 1e-07
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 7/134 (5%)
Query: 150 RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALH 209
R + + L+R GA++++ NK T L +AA + + DV++ L GA+++ G TALH
Sbjct: 537 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 596
Query: 210 FAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIE 268
AA GH LL +G+ + + G T AA+ +V +IL+ + ++
Sbjct: 597 RAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTPIRTSDV-- 650
Query: 269 AYELLGASFANDKE 282
Y LL AS A D E
Sbjct: 651 DYRLLEASKAGDLE 664
Score = 56.0 bits (129), Expect = 4e-07
Identities = 37/106 (34%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
++ L A+G G +V+ L++ GA+V+ PL AC G ++V L+ GAD +
Sbjct: 217 SSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA + R G +AL A
Sbjct: 277 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA + H + + L++ GA+VN + TPL A D+++ L +HGA
Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AA G+L + LL G+ +L G TA E
Sbjct: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNE 633
Score = 51.2 bits (117), Expect = 1e-05
Identities = 64/220 (29%), Positives = 90/220 (40%), Gaps = 35/220 (15%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K +PL AA GR+ V LL+ V +G G L A GH
Sbjct: 214 GRKSSPLHFAAGFGRKDVVEHLLQ-MGANVHARDDG----------GLIPLHNACSFGHA 262
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN---------- 168
+V L+ GAD N TPL A +G++D+ L++HGAD + N
Sbjct: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Query: 169 ----------KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGH 216
+Y L+ AA G + + LL + V+ A G +T LH AA
Sbjct: 323 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNR 381
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+V LL HGA + ++ G+ PL A V E+L
Sbjct: 382 VRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL 421
Score = 50.8 bits (116), Expect = 2e-05
Identities = 68/232 (29%), Positives = 100/232 (43%), Gaps = 39/232 (16%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G G L
Sbjct: 358 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKG----------GLVPL 406
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + L+K GA VN TPL A + R+++ L+ HGAD N
Sbjct: 407 HNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNC 466
Query: 170 YNNTCLMIA-----------AYKGYLDVVQFLLDSGARVDDRALC-----------GATA 207
+ + + +A +KG+ ++Q ++ + L TA
Sbjct: 467 HGKSAVDMAPTPELRERLTYEFKGH-SLLQAAREADLAKVKKTLALEIINFKQPQSHETA 525
Query: 208 LHFAAECGH---AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH A H V LL GA + N++ MTPL AAERA V+E+L
Sbjct: 526 LHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 577
Score = 43.6 bits (98), Expect = 0.002
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 11/154 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL + L+ G+D + +S A G + V+ ++ I
Sbjct: 591 GQTALHRAALAGHLQTCRLLLSYGSDPS----IISLQGFTAAQMGN-EAVQQILSESTPI 645
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCS 222
++ + L+ A+ G L+ V+ L S V+ R L G +T LHFAA +VV
Sbjct: 646 RTSDV--DYRLLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEY 702
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL HGA + ++ G+ PL A V E+L
Sbjct: 703 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 736
Score = 37.5 bits (83), Expect = 0.15
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
C + + + V + LL GA V+++ T LH AAE H V+ L HGAKM
Sbjct: 528 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNAL 587
Query: 234 EN-GMTPLQCAA 244
+ G T L AA
Sbjct: 588 DTLGQTALHRAA 599
>BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
protein.
Length = 1327
Score = 74.5 bits (175), Expect = 1e-12
Identities = 61/207 (29%), Positives = 94/207 (45%), Gaps = 12/207 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 750 KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLD 809
Query: 112 ASGAGHLAIVKRL-VKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA V++L + STPL A L++ +YL+ HGAD++ +K
Sbjct: 810 AAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG 869
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++D+ L+ V+ T LH AA+ G + LL HGA
Sbjct: 870 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 929
Query: 230 MLTNENGMTPLQCA-AERARASVVEIL 255
+ N+ G TPL A A+ RA +++ +
Sbjct: 930 TMKNQEGQTPLDLATADDIRALLIDAM 956
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/136 (36%), Positives = 65/136 (47%), Gaps = 2/136 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
AS AG L VK+L + + STPL A R+ +V+YL+ HGAD+H +K
Sbjct: 657 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 716
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 230 MLTNENGMTPLQCAAE 245
N +G TPL E
Sbjct: 777 TKKNRDGNTPLDLVKE 792
Score = 61.3 bits (142), Expect = 1e-08
Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 11/197 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 279 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDE 338
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 339 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 398
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K L A G+ +V + LL GA V+ L T LH AA V LL HG
Sbjct: 399 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 458
Query: 228 A-KMLTNENGMTPLQCA 243
A L N +G + + A
Sbjct: 459 ADPTLVNCHGKSAVDMA 475
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/173 (31%), Positives = 74/173 (42%), Gaps = 22/173 (12%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A GH + + LV+ GA VN A TPL A +G+ +I K L++HGAD
Sbjct: 717 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 776
Query: 165 HKANKYNNT--------------------CLMIAAYKGYLDVVQFL-LDSGARVDDRALC 203
K N+ NT L+ AA KG L VQ L D
Sbjct: 777 TKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 836
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+T LH AA + V LL+HGA + ++ G+ PL AA + +L
Sbjct: 837 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 4/137 (2%)
Query: 116 GHLAIVKRLVKAGADVNHATRT--VSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNT 173
G ++ VKRLV A A+VN S+PL A GR D+V++L++ GA++H +
Sbjct: 193 GDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLI 251
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-KMLT 232
L A G+ +VV LL GA + R T LH AA G V LL HGA +
Sbjct: 252 PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 311
Query: 233 NENGMTPLQCAAERARA 249
N +G + L A A+A
Sbjct: 312 NTDGKSALDLADPSAKA 328
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/108 (33%), Positives = 56/108 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G +++V+ L+ GADV+ + PL AC G ++ + LVRHGA ++
Sbjct: 685 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
A+ + T L AA KG ++ + LL GA + G T L E
Sbjct: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 792
Score = 57.6 bits (133), Expect = 1e-07
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 7/134 (5%)
Query: 150 RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALH 209
R + + L+R GA++++ NK T L +AA + + DV++ L GA+++ G TALH
Sbjct: 537 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 596
Query: 210 FAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIE 268
AA GH LL +G+ + + G T AA+ +V +IL+ + ++
Sbjct: 597 RAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTPIRTSDV-- 650
Query: 269 AYELLGASFANDKE 282
Y LL AS A D E
Sbjct: 651 DYRLLEASKAGDLE 664
Score = 56.0 bits (129), Expect = 4e-07
Identities = 37/106 (34%), Positives = 55/106 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
++ L A+G G +V+ L++ GA+V+ PL AC G ++V L+ GAD +
Sbjct: 217 SSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN 276
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFA 211
+ +N T L AA KG +DV LL GA + R G +AL A
Sbjct: 277 ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA + H + + L++ GA+VN + TPL A D+++ L +HGA
Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AA G+L + LL G+ +L G TA E
Sbjct: 584 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNE 633
Score = 51.2 bits (117), Expect = 1e-05
Identities = 64/220 (29%), Positives = 90/220 (40%), Gaps = 35/220 (15%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G K +PL AA GR+ V LL+ V +G G L A GH
Sbjct: 214 GRKSSPLHFAAGFGRKDVVEHLLQ-MGANVHARDDG----------GLIPLHNACSFGHA 262
Query: 119 AIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN---------- 168
+V L+ GAD N TPL A +G++D+ L++HGAD + N
Sbjct: 263 EVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Query: 169 ----------KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGH 216
+Y L+ AA G + + LL + V+ A G +T LH AA
Sbjct: 323 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNR 381
Query: 217 AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+V LL HGA + ++ G+ PL A V E+L
Sbjct: 382 VRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL 421
Score = 50.8 bits (116), Expect = 2e-05
Identities = 68/232 (29%), Positives = 100/232 (43%), Gaps = 39/232 (16%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G G L
Sbjct: 358 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKG----------GLVPL 406
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + L+K GA VN TPL A + R+++ L+ HGAD N
Sbjct: 407 HNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNC 466
Query: 170 YNNTCLMIA-----------AYKGYLDVVQFLLDSGARVDDRALC-----------GATA 207
+ + + +A +KG+ ++Q ++ + L TA
Sbjct: 467 HGKSAVDMAPTPELRERLTYEFKGH-SLLQAAREADLAKVKKTLALEIINFKQPQSHETA 525
Query: 208 LHFAAECGH---AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH A H V LL GA + N++ MTPL AAERA V+E+L
Sbjct: 526 LHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 577
Score = 43.6 bits (98), Expect = 0.002
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 11/154 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL + L+ G+D + +S A G + V+ ++ I
Sbjct: 591 GQTALHRAALAGHLQTCRLLLSYGSDPS----IISLQGFTAAQMGN-EAVQQILSESTPI 645
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCS 222
++ + L+ A+ G L+ V+ L S V+ R L G +T LHFAA +VV
Sbjct: 646 RTSDV--DYRLLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEY 702
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL HGA + ++ G+ PL A V E+L
Sbjct: 703 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 736
Score = 37.5 bits (83), Expect = 0.15
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
C + + + V + LL GA V+++ T LH AAE H V+ L HGAKM
Sbjct: 528 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNAL 587
Query: 234 EN-GMTPLQCAA 244
+ G T L AA
Sbjct: 588 DTLGQTALHRAA 599
>AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
variant protein.
Length = 1055
Score = 74.5 bits (175), Expect = 1e-12
Identities = 61/207 (29%), Positives = 94/207 (45%), Gaps = 12/207 (5%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD---------EYVIEGATALWC 111
K TPL AA G+ ++LL+ P +G D + ++ G AL
Sbjct: 478 KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLD 537
Query: 112 ASGAGHLAIVKRL-VKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
A+ G LA V++L + STPL A L++ +YL+ HGAD++ +K
Sbjct: 538 AAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG 597
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L AA G++D+ L+ V+ T LH AA+ G + LL HGA
Sbjct: 598 GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP 657
Query: 230 MLTNENGMTPLQCA-AERARASVVEIL 255
+ N+ G TPL A A+ RA +++ +
Sbjct: 658 TMKNQEGQTPLDLATADDIRALLIDAM 684
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/136 (36%), Positives = 65/136 (47%), Gaps = 2/136 (1%)
Query: 112 ASGAGHLAIVKRLVKA-GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
AS AG L VK+L + + STPL A R+ +V+YL+ HGAD+H +K
Sbjct: 385 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 444
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA-K 229
L A G+ +V + L+ GA V+ L T LH AA G + LL HGA
Sbjct: 445 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 504
Query: 230 MLTNENGMTPLQCAAE 245
N +G TPL E
Sbjct: 505 TKKNRDGNTPLDLVKE 520
Score = 61.3 bits (142), Expect = 1e-08
Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 11/197 (5%)
Query: 58 DGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFD------EYVIEGA----T 107
D TPL AA G+ +LL+ P T+G D + V+ G
Sbjct: 7 DNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDE 66
Query: 108 ALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKA 167
L A ++ L + + + STPL A R+ IV+ L++HGAD+H
Sbjct: 67 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 126
Query: 168 NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
+K L A G+ +V + LL GA V+ L T LH AA V LL HG
Sbjct: 127 DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHG 186
Query: 228 A-KMLTNENGMTPLQCA 243
A L N +G + + A
Sbjct: 187 ADPTLVNCHGKSAVDMA 203
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/173 (31%), Positives = 74/173 (42%), Gaps = 22/173 (12%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G L A GH + + LV+ GA VN A TPL A +G+ +I K L++HGAD
Sbjct: 445 GLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADP 504
Query: 165 HKANKYNNT--------------------CLMIAAYKGYLDVVQFL-LDSGARVDDRALC 203
K N+ NT L+ AA KG L VQ L D
Sbjct: 505 TKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR 564
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
+T LH AA + V LL+HGA + ++ G+ PL AA + +L
Sbjct: 565 NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 617
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/108 (33%), Positives = 56/108 (51%)
Query: 106 ATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIH 165
+T L A+G +++V+ L+ GADV+ + PL AC G ++ + LVRHGA ++
Sbjct: 413 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 472
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
A+ + T L AA KG ++ + LL GA + G T L E
Sbjct: 473 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 520
Score = 57.6 bits (133), Expect = 1e-07
Identities = 43/134 (32%), Positives = 69/134 (51%), Gaps = 7/134 (5%)
Query: 150 RLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALH 209
R + + L+R GA++++ NK T L +AA + + DV++ L GA+++ G TALH
Sbjct: 265 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALH 324
Query: 210 FAAECGHAAVVCSLLDHGA-KMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIE 268
AA GH LL +G+ + + G T AA+ +V +IL+ + ++
Sbjct: 325 RAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSESTPIRTSDV-- 378
Query: 269 AYELLGASFANDKE 282
Y LL AS A D E
Sbjct: 379 DYRLLEASKAGDLE 392
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 107 TALWCASGAGH---LAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
TAL CA + H + + L++ GA+VN + TPL A D+++ L +HGA
Sbjct: 252 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 311
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAE 213
++ + T L AA G+L + LL G+ +L G TA E
Sbjct: 312 MNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNE 361
Score = 50.8 bits (116), Expect = 2e-05
Identities = 68/232 (29%), Positives = 100/232 (43%), Gaps = 39/232 (16%)
Query: 51 LNIDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATAL 109
LN++ SDG K TPL AA + R V++LL+ V + +G G L
Sbjct: 86 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKG----------GLVPL 134
Query: 110 WCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANK 169
A GH + + L+K GA VN TPL A + R+++ L+ HGAD N
Sbjct: 135 HNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNC 194
Query: 170 YNNTCLMIA-----------AYKGYLDVVQFLLDSGARVDDRALC-----------GATA 207
+ + + +A +KG+ ++Q ++ + L TA
Sbjct: 195 HGKSAVDMAPTPELRERLTYEFKGH-SLLQAAREADLAKVKKTLALEIINFKQPQSHETA 253
Query: 208 LHFAAECGH---AAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LH A H V LL GA + N++ MTPL AAERA V+E+L
Sbjct: 254 LHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL 305
Score = 43.6 bits (98), Expect = 0.002
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 11/154 (7%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ AGHL + L+ G+D + +S A G + V+ ++ I
Sbjct: 319 GQTALHRAALAGHLQTCRLLLSYGSDPS----IISLQGFTAAQMGN-EAVQQILSESTPI 373
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCS 222
++ + L+ A+ G L+ V+ L S V+ R L G +T LHFAA +VV
Sbjct: 374 RTSDV--DYRLLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEY 430
Query: 223 LLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
LL HGA + ++ G+ PL A V E+L
Sbjct: 431 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 464
Score = 39.1 bits (87), Expect = 0.049
Identities = 43/150 (28%), Positives = 63/150 (42%), Gaps = 24/150 (16%)
Query: 129 ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKAN-------------------- 168
AD N TPL A +G++D+ L++HGAD + N
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTG 60
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--ATALHFAAECGHAAVVCSLLDH 226
+Y L+ AA G + + LL + V+ A G +T LH AA +V LL H
Sbjct: 61 EYKKDELLEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 119
Query: 227 GAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + ++ G+ PL A V E+L
Sbjct: 120 GADVHAKDKGGLVPLHNACSYGHYEVTELL 149
Score = 37.5 bits (83), Expect = 0.15
Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN 233
C + + + V + LL GA V+++ T LH AAE H V+ L HGAKM
Sbjct: 256 CAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNAL 315
Query: 234 EN-GMTPLQCAA 244
+ G T L AA
Sbjct: 316 DTLGQTALHRAA 327
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 74.1 bits (174), Expect = 1e-12
Identities = 58/168 (34%), Positives = 78/168 (46%), Gaps = 5/168 (2%)
Query: 93 EGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRL 151
E V D +G TAL+ A+ G V+ L GA R TPL AA G
Sbjct: 35 ETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKERKRKWTPLHAAAASGHT 94
Query: 152 DIVKYLVRHG--ADIHKA-NKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
D + L+ G ADI + Y T LM+A G++D V LL+ G+ D L G TAL
Sbjct: 95 DSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTAL 154
Query: 209 HFAAECGHAAVVCSLLDHGAKMLTNE-NGMTPLQCAAERARASVVEIL 255
H A G + +LLDH A +L + G TP+ A+ +V+ L
Sbjct: 155 HRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTL 202
Score = 64.5 bits (150), Expect = 1e-09
Identities = 53/161 (32%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHG-A 162
+G T L A+ A +++ ++ L++ A+VN T T L A G+ V++L+ G A
Sbjct: 286 KGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKA 345
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGAT------ALHFAAECGH 216
D+ ++ NT L +A KG+ +L A D L AT LH AA G
Sbjct: 346 DLTVLDENKNTALHLACSKGHEKCALMIL---AETQDLGLINATNSALQMPLHIAARNGL 402
Query: 217 AAVVCSLLDHGAKML-TNENGMTP-LQCAAERARASVVEIL 255
A+VV +LL HGA +L +E G TP L CA + A + ++
Sbjct: 403 ASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALI 443
Score = 58.8 bits (136), Expect = 6e-08
Identities = 41/121 (33%), Positives = 56/121 (46%), Gaps = 3/121 (2%)
Query: 107 TALWCASGAGHLAIVKRLVKAG--ADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGAD 163
T L A+ +GH + L+ +G AD+ TPL A G +D V L+ G+
Sbjct: 83 TPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHLLLEKGST 142
Query: 164 IHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
A+ T L A G D + LLD A V R G T +H A+ CGH AV+ +L
Sbjct: 143 ADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTL 202
Query: 224 L 224
L
Sbjct: 203 L 203
Score = 57.2 bits (132), Expect = 2e-07
Identities = 58/190 (30%), Positives = 80/190 (42%), Gaps = 9/190 (4%)
Query: 107 TALWCASGAGHLAIVKRLVKA-GADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADI 164
T L CA + + L+ A GA + ++ T TPL AA F + ++ L++H A++
Sbjct: 254 TPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEV 313
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA--TALHFAAECGHAAVVCS 222
+ + T LM AA G V+FLL G + D L TALH A GH
Sbjct: 314 NATDHTGRTALMTAAENGQTAAVEFLLYRG-KADLTVLDENKNTALHLACSKGHEKCALM 372
Query: 223 LL----DHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFA 278
+L D G TN PL AA ASVV+ L + A E + A
Sbjct: 373 ILAETQDLGLINATNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAP 432
Query: 279 NDKEYYCLRM 288
N CL +
Sbjct: 433 NKDVADCLAL 442
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/199 (26%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 61 KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAI 120
K TPL AA G ++ +L++ + T D Y G T L A GH+
Sbjct: 81 KWTPLHAAAASGHTDSLHLLIDSGE-----RADITDVMDVY---GQTPLMLAIMNGHVDC 132
Query: 121 VKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAY 180
V L++ G+ + A T L G D + L+ H A + + T + +A+
Sbjct: 133 VHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASA 192
Query: 181 KGYLDVVQFLLDSGARVD--DRAL--CGATALHFAAECGHAAVVCSLLDHGAKMLTNENG 236
G+ V++ LL + D D + G + +H+A+ GH + LL+H N
Sbjct: 193 CGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNP 252
Query: 237 MTPLQCAAERARASVVEIL 255
TPL CA + S E+L
Sbjct: 253 FTPLHCAVINNQDSTTEML 271
Score = 42.7 bits (96), Expect = 0.004
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 175 LMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE 234
L +AAY G+ + ++ L ++ +D R G TAL A E G V L HGA L E
Sbjct: 18 LHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKE 77
Query: 235 --NGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLG 274
TPL AA + +L E RA+ + ++ G
Sbjct: 78 RKRKWTPLHAAAASGHTDSLHLLIDSGE--RADITDVMDVYG 117
Score = 40.3 bits (90), Expect = 0.021
Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 12/210 (5%)
Query: 55 VCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASG 114
+C D TP+ A+ G +R LL+ L T+ +Y G + + AS
Sbjct: 177 LCRDFKGRTPIHLASACGHTAVLRTLLQ-----AALSTDPLDAGVDY--SGYSPMHWASY 229
Query: 115 AGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRH-GADI-HKANKYNN 172
GH ++ L++ + ++ TPL A + + L+ GA I + +
Sbjct: 230 TGHEDCLELLLEH-SPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGR 288
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L AA+ + ++ LL A V+ G TAL AAE G A V LL G LT
Sbjct: 289 TPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLT 348
Query: 233 --NENGMTPLQCAAERARASVVEILAARPE 260
+EN T L A + ++ A +
Sbjct: 349 VLDENKNTALHLACSKGHEKCALMILAETQ 378
>D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target
subunit 1 protein.
Length = 1030
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein.
Length = 1030
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein.
Length = 730
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein.
Length = 692
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase target
subunit 1 variant 2 protein.
Length = 974
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase target
subunit 1 variant protein.
Length = 995
Score = 72.5 bits (170), Expect = 4e-12
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 86 PPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAA 145
PPV + VKFD+ GA L A +G V +L+ GAD+N+A T L A
Sbjct: 26 PPVVKRQKTKVKFDD----GAVFL-AACSSGDTDEVLKLLHRGADINYANVDGLTALHQA 80
Query: 146 CFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGA 205
C + +D+VK+LV +GA+I++ + L AA GYLD+ +FL+ GA V G
Sbjct: 81 CIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGD 140
Query: 206 TALHFAAE 213
T L A E
Sbjct: 141 TPLDIAEE 148
Score = 69.7 bits (163), Expect = 3e-11
Identities = 60/190 (31%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 144 AACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALC 203
AAC G D V L+ GADI+ AN T L A +D+V+FL+++GA ++
Sbjct: 46 AACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNE 105
Query: 204 GATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASV---------VE 253
G LH AA CG+ + L+ GA + N G TPL A E A + V+
Sbjct: 106 GWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVD 165
Query: 254 ILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRP- 312
I AAR E R +A + L + ND + + LH A A Y +++
Sbjct: 166 IEAARKEEERIMLRDARQWLNSGHINDVRH--AKSGGTALHVAAAKGYTEVLKLLIQAGY 223
Query: 313 STPIPAYDNW 322
I YD W
Sbjct: 224 DVNIKDYDGW 233
Score = 50.8 bits (116), Expect = 2e-05
Identities = 45/146 (30%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 45 DEIDDLLNIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIE 104
+ +++LL +V GV I AAR E RI+L R + G + +
Sbjct: 149 EAMEELLQNEVNRQGVD----IEAARKEEE---RIMLRDARQWL---NSGHINDVRHAKS 198
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ G+ ++K L++AG DVN TPL AA G+ + + LV + D+
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258
Query: 165 HKANKYNNTCLMIA--AYKGYLDVVQ 188
NK T +A GYL+ +Q
Sbjct: 259 EMVNKVGQTAFDVADEDILGYLEELQ 284
Score = 50.0 bits (114), Expect = 3e-05
Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 28/181 (15%)
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
++G TAL A ++ +VK LV+ GA++N PL AA G LDI ++L+ GA
Sbjct: 71 VDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGA 130
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQ--------------------FLLD-----SGARV 197
+ N +T L IA + +++Q L D + +
Sbjct: 131 HVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHI 190
Query: 198 DD--RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEI 254
+D A G TALH AA G+ V+ L+ G + + + +G TPL AA + I
Sbjct: 191 NDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRI 250
Query: 255 L 255
L
Sbjct: 251 L 251
Score = 43.2 bits (97), Expect = 0.003
Identities = 30/87 (34%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 160 HGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAV 219
H D+ A K T L +AA KGY +V++ L+ +G V+ + G T LH AA G
Sbjct: 189 HINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247
Query: 220 VCSLLDHGAKM-LTNENGMTPLQCAAE 245
L+D+ M + N+ G T A E
Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVADE 274
Score = 35.9 bits (79), Expect = 0.46
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 169 KYNNTCLMIAAYK-GYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHG 227
K+++ + +AA G D V LL GA ++ + G TALH A + +V L+++G
Sbjct: 37 KFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENG 96
Query: 228 AKMLTNEN-GMTPLQCAAERARASVVEIL 255
A + +N G PL AA + E L
Sbjct: 97 ANINQPDNEGWIPLHAAASCGYLDIAEFL 125
>CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein.
Length = 278
Score = 72.1 bits (169), Expect = 6e-12
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 16/193 (8%)
Query: 46 EIDDLLNIDVCSDGV---KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
++ L+ C + V TPL A+ G+ V++LL + D
Sbjct: 34 QLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLA-----------AGAQVDARN 82
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I+G+T L A +G + VK L+ GA VN T S PL AC G + V+ L+ GA
Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTAS-PLHEACMSGSSECVRLLIDVGA 141
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ + + T L +A + +LD V+ LL++GA V+ L TALH AA+ + ++
Sbjct: 142 NLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKL-HETALHHAAKVKNVDLIEM 200
Query: 223 LLDHGAKMLTNEN 235
L++ G + +N
Sbjct: 201 LIEFGGNIYARDN 213
Score = 65.7 bits (153), Expect = 5e-10
Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G +++L+++GA VN T TPL AA +G+ V+ L+ GA + N
Sbjct: 26 AAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDG 85
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
+T L A G ++ V+ LL GA+V+ L A+ LH A G + V L+D GA +
Sbjct: 86 STPLCDACASGSIECVKLLLSYGAKVNP-PLYTASPLHEACMSGSSECVRLLIDVGANLE 144
Query: 232 TNE-NGMTPLQCAAERARASVVEIL 255
++ + TPL A R V++L
Sbjct: 145 AHDCHFGTPLHVACAREHLDCVKVL 169
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 1/157 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
++ ++ T L AS G V+ L+ AGA V+ STPL AC G ++ VK L+
Sbjct: 46 NQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLL 105
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA ++ Y + L A G + V+ L+D GA ++ T LH A H
Sbjct: 106 SYGAKVNPP-LYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLD 164
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
V LL+ GA + + T L AA+ ++E+L
Sbjct: 165 CVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEML 201
Score = 48.4 bits (110), Expect = 8e-05
Identities = 36/116 (31%), Positives = 55/116 (47%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TP+ A G ++ L+ GA +++ + T L A+ +G VQ LL +GA+VD
Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDA 80
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
R + G+T L A G V LL +GAK+ +PL A + V +L
Sbjct: 81 RNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Score = 33.5 bits (73), Expect = 2.4
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 530 DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVA 564
+ C + RLL+D GA+++A D + TPLHVA
Sbjct: 123 EACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVA 157
Score = 31.9 bits (69), Expect = 7.5
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 13/65 (20%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
L++ GA V+ ++ TPLH A + Q A C V LL+ GA VDA ++D
Sbjct: 38 LIESGACVNQVTVDSITPLHAASLQGQ-----------ARC--VQLLLAAGAQVDARNID 84
Query: 603 GITPL 607
G TPL
Sbjct: 85 GSTPL 89
>BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS
box-containing 9 protein.
Length = 294
Score = 72.1 bits (169), Expect = 6e-12
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 4/177 (2%)
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH ++ L+ G VN T +PL AC G L VK L++HGA ++ +T L
Sbjct: 47 GHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPL 106
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN 235
A G D V LL GA V + A+ +H AA GH V SL+ +G + +
Sbjct: 107 FNACVSGSWDCVNLLLQHGASVQPESDL-ASPIHEAARRGHVECVNSLIAYGGNIDHKIS 165
Query: 236 GM-TPLQCAAE-RARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAY 290
+ TPL A E + RA V ++L + +V + + ++ L + +E CL M +
Sbjct: 166 HLGTPLYLACENQQRACVKKLLESGADVNQGKGQDS-PLHAVARTASEELACLLMDF 221
Score = 41.5 bits (93), Expect = 0.009
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ GH+ V L+ G +++H + TPL AC + VK L+ GAD+++ K
Sbjct: 141 AARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ-GKGQ 199
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGA 195
++ L A ++ L+D GA
Sbjct: 200 DSPLHAVARTASEELACLLMDFGA 223
Score = 39.1 bits (87), Expect = 0.049
Identities = 32/118 (27%), Positives = 49/118 (41%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
+P+ A G ++ L+ G ++ + + L A G+L V+ LL GA+V+
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAA 257
T L A G V LL HGA + + +P+ AA R V L A
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIA 155
Score = 31.5 bits (68), Expect = 9.9
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D + T L+ A A VK+L+++GADVN + +PL A ++ L+
Sbjct: 161 DHKISHLGTPLYLACENQQRACVKKLLESGADVNQG-KGQDSPLHAVARTASEELACLLM 219
Query: 159 RHGADIHKAN 168
GAD N
Sbjct: 220 DFGADTQAKN 229
>AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS
box-containing 13 protein.
Length = 278
Score = 72.1 bits (169), Expect = 6e-12
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 16/193 (8%)
Query: 46 EIDDLLNIDVCSDGV---KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
++ L+ C + V TPL A+ G+ V++LL + D
Sbjct: 34 QLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLA-----------AGAQVDARN 82
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I+G+T L A +G + VK L+ GA VN T S PL AC G + V+ L+ GA
Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTAS-PLHEACMSGSSECVRLLIDVGA 141
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ + + T L +A + +LD V+ LL++GA V+ L TALH AA+ + ++
Sbjct: 142 NLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKL-HETALHHAAKVKNVDLIEM 200
Query: 223 LLDHGAKMLTNEN 235
L++ G + +N
Sbjct: 201 LIEFGGNIYARDN 213
Score = 65.7 bits (153), Expect = 5e-10
Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G +++L+++GA VN T TPL AA +G+ V+ L+ GA + N
Sbjct: 26 AAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDG 85
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
+T L A G ++ V+ LL GA+V+ L A+ LH A G + V L+D GA +
Sbjct: 86 STPLCDACASGSIECVKLLLSYGAKVNP-PLYTASPLHEACMSGSSECVRLLIDVGANLE 144
Query: 232 TNE-NGMTPLQCAAERARASVVEIL 255
++ + TPL A R V++L
Sbjct: 145 AHDCHFGTPLHVACAREHLDCVKVL 169
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 1/157 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
++ ++ T L AS G V+ L+ AGA V+ STPL AC G ++ VK L+
Sbjct: 46 NQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLL 105
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA ++ Y + L A G + V+ L+D GA ++ T LH A H
Sbjct: 106 SYGAKVNPP-LYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLD 164
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
V LL+ GA + + T L AA+ ++E+L
Sbjct: 165 CVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEML 201
Score = 48.4 bits (110), Expect = 8e-05
Identities = 36/116 (31%), Positives = 55/116 (47%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TP+ A G ++ L+ GA +++ + T L A+ +G VQ LL +GA+VD
Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDA 80
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
R + G+T L A G V LL +GAK+ +PL A + V +L
Sbjct: 81 RNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Score = 33.5 bits (73), Expect = 2.4
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 530 DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVA 564
+ C + RLL+D GA+++A D + TPLHVA
Sbjct: 123 EACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVA 157
Score = 31.9 bits (69), Expect = 7.5
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 13/65 (20%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
L++ GA V+ ++ TPLH A + Q A C V LL+ GA VDA ++D
Sbjct: 38 LIESGACVNQVTVDSITPLHAASLQGQ-----------ARC--VQLLLAAGAQVDARNID 84
Query: 603 GITPL 607
G TPL
Sbjct: 85 GSTPL 89
>AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens
cDNA FLJ20636 fis, clone KAT03434. ).
Length = 262
Score = 72.1 bits (169), Expect = 6e-12
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 4/177 (2%)
Query: 116 GHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCL 175
GH ++ L+ G VN T +PL AC G L VK L++HGA ++ +T L
Sbjct: 47 GHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPL 106
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN 235
A G D V LL GA V + A+ +H AA GH V SL+ +G + +
Sbjct: 107 FNACVSGSWDCVNLLLQHGASVQPESDL-ASPIHEAARRGHVECVNSLIAYGGNIDHKIS 165
Query: 236 GM-TPLQCAAE-RARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAY 290
+ TPL A E + RA V ++L + +V + + ++ L + +E CL M +
Sbjct: 166 HLGTPLYLACENQQRACVKKLLESGADVNQGKGQDS-PLHAVARTASEELACLLMDF 221
Score = 41.5 bits (93), Expect = 0.009
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ GH+ V L+ G +++H + TPL AC + VK L+ GAD+++ K
Sbjct: 141 AARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ-GKGQ 199
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGA 195
++ L A ++ L+D GA
Sbjct: 200 DSPLHAVARTASEELACLLMDFGA 223
Score = 39.1 bits (87), Expect = 0.049
Identities = 32/118 (27%), Positives = 49/118 (41%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
+P+ A G ++ L+ G ++ + + L A G+L V+ LL GA+V+
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAA 257
T L A G V LL HGA + + +P+ AA R V L A
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIA 155
Score = 31.5 bits (68), Expect = 9.9
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
D + T L+ A A VK+L+++GADVN + +PL A ++ L+
Sbjct: 161 DHKISHLGTPLYLACENQQRACVKKLLESGADVNQG-KGQDSPLHAVARTASEELACLLM 219
Query: 159 RHGADIHKAN 168
GAD N
Sbjct: 220 DFGADTQAKN 229
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 598 RGADVTLTDNEENICLHWASF 618
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 541 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 600
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 601 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 660
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 661 FLSRGANPELRNKEGDTAWDLTPERS 686
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 615
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 616 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 675
Query: 172 NT 173
+T
Sbjct: 676 DT 677
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 399 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 458
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 459 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 518
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 519 RGADVTLTDNEENICLHWASFTGSAAIAEVL 549
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 399 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 458
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 459 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 518
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 519 RGADVTLTDNEENICLHWASF 539
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 462 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 521
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 522 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 581
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 582 FLSRGANPELRNKEGDTAWDLTPERS 607
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 488 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 536
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 537 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 596
Query: 172 NT 173
+T
Sbjct: 597 DT 598
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 365 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 424
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 425 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 484
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 485 RGADVTLTDNEENICLHWASFTGSAAIAEVL 515
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 365 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 424
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 425 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 484
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 485 RGADVTLTDNEENICLHWASF 505
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 428 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 487
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 488 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 547
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 548 FLSRGANPELRNKEGDTAWDLTPERS 573
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 454 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 502
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 503 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 562
Query: 172 NT 173
+T
Sbjct: 563 DT 564
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 675 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 734
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 735 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 794
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 795 RGADVTLTDNEENICLHWASFTGSAAIAEVL 825
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 675 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 734
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 735 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 794
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 795 RGADVTLTDNEENICLHWASF 815
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 738 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 797
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 798 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 857
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 858 FLSRGANPELRNKEGDTAWDLTPERS 883
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 764 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 812
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 813 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 872
Query: 172 NT 173
+T
Sbjct: 873 DT 874
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 598 RGADVTLTDNEENICLHWASF 618
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 541 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 600
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 601 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 660
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 661 FLSRGANPELRNKEGDTAWDLTPERS 686
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 615
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 616 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 675
Query: 172 NT 173
+T
Sbjct: 676 DT 677
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 686 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 745
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 746 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 805
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 806 RGADVTLTDNEENICLHWASFTGSAAIAEVL 836
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 686 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 745
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 746 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 805
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 806 RGADVTLTDNEENICLHWASF 826
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 749 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 808
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 809 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 868
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 869 FLSRGANPELRNKEGDTAWDLTPERS 894
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 775 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 823
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 824 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 883
Query: 172 NT 173
+T
Sbjct: 884 DT 885
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 520 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 579
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 580 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 639
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 640 RGADVTLTDNEENICLHWASFTGSAAIAEVL 670
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 520 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 579
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 580 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 639
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 640 RGADVTLTDNEENICLHWASF 660
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 583 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 642
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 643 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 702
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 703 FLSRGANPELRNKEGDTAWDLTPERS 728
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 609 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 657
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 658 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 717
Query: 172 NT 173
+T
Sbjct: 718 DT 719
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 598 RGADVTLTDNEENICLHWASF 618
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 541 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 600
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 601 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 660
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 661 FLSRGANPELRNKEGDTAWDLTPERS 686
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 615
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 616 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 675
Query: 172 NT 173
+T
Sbjct: 676 DT 677
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1210
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 807 RGADVTLTDNEENICLHWASF 827
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 750 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 809
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 810 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 869
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 870 FLSRGANPELRNKEGDTAWDLTPERS 895
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 824
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 825 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 884
Query: 172 NT 173
+T
Sbjct: 885 DT 886
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1176
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 773 RGADVTLTDNEENICLHWASF 793
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 716 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 775
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 776 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 835
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 836 FLSRGANPELRNKEGDTAWDLTPERS 861
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 790
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 791 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 850
Query: 172 NT 173
+T
Sbjct: 851 DT 852
>AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 807 RGADVTLTDNEENICLHWASF 827
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 750 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 809
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 810 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 869
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 870 FLSRGANPELRNKEGDTAWDLTPERS 895
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 824
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 825 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 884
Query: 172 NT 173
+T
Sbjct: 885 DT 886
>AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 773 RGADVTLTDNEENICLHWASF 793
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 716 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 775
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 776 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 835
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 836 FLSRGANPELRNKEGDTAWDLTPERS 861
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 790
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 791 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 850
Query: 172 NT 173
+T
Sbjct: 851 DT 852
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 864 RGADVTLTDNEENICLHWASFTGSAAIAEVL 894
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 864 RGADVTLTDNEENICLHWASF 884
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 807 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 866
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 867 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 926
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 927 FLSRGANPELRNKEGDTAWDLTPERS 952
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 833 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 881
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 882 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 941
Query: 172 NT 173
+T
Sbjct: 942 DT 943
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 830 RGADVTLTDNEENICLHWASFTGSAAIAEVL 860
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 830 RGADVTLTDNEENICLHWASF 850
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 773 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 832
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 833 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 892
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 893 FLSRGANPELRNKEGDTAWDLTPERS 918
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 799 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 847
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 848 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 907
Query: 172 NT 173
+T
Sbjct: 908 DT 909
>AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 773 RGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 653 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 712
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 713 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 772
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 773 RGADVTLTDNEENICLHWASF 793
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 716 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 775
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 776 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 835
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 836 FLSRGANPELRNKEGDTAWDLTPERS 861
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 790
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 791 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 850
Query: 172 NT 173
+T
Sbjct: 851 DT 852
>AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 807 RGADVTLTDNEENICLHWASF 827
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 750 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 809
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 810 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 869
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 870 FLSRGANPELRNKEGDTAWDLTPERS 895
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 824
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 825 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 884
Query: 172 NT 173
+T
Sbjct: 885 DT 886
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 864 RGADVTLTDNEENICLHWASFTGSAAIAEVL 894
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 744 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 803
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 804 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 863
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 864 RGADVTLTDNEENICLHWASF 884
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 807 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 866
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 867 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 926
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 927 FLSRGANPELRNKEGDTAWDLTPERS 952
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 833 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 881
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 882 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 941
Query: 172 NT 173
+T
Sbjct: 942 DT 943
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 830 RGADVTLTDNEENICLHWASFTGSAAIAEVL 860
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 710 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 769
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 770 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 829
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 830 RGADVTLTDNEENICLHWASF 850
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 773 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 832
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 833 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 892
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 893 FLSRGANPELRNKEGDTAWDLTPERS 918
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 799 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 847
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 848 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 907
Query: 172 NT 173
+T
Sbjct: 908 DT 909
>AK123197-1|BAC85555.1| 131|Homo sapiens protein ( Homo sapiens
cDNA FLJ41203 fis, clone BRACE3000071. ).
Length = 131
Score = 71.7 bits (168), Expect = 8e-12
Identities = 38/87 (43%), Positives = 53/87 (60%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ AGH+ V+ LV GAD+N T L AA G + +V+ L++HGA+IH
Sbjct: 3 AAYAGHIDCVRELVLQGADINLQREDGGTALLAASQYGHMQVVETLLKHGANIHDQLYDG 62
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVD 198
T L +AA GYLDV++ LL SGA+V+
Sbjct: 63 ATALFLAAQGGYLDVIRLLLASGAKVN 89
Score = 67.7 bits (158), Expect = 1e-10
Identities = 37/95 (38%), Positives = 53/95 (55%)
Query: 145 ACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG 204
A + G +D V+ LV GADI+ + T L+ A+ G++ VV+ LL GA + D+ G
Sbjct: 3 AAYAGHIDCVRELVLQGADINLQREDGGTALLAASQYGHMQVVETLLKHGANIHDQLYDG 62
Query: 205 ATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTP 239
ATAL AA+ G+ V+ LL GAK+ G P
Sbjct: 63 ATALFLAAQGGYLDVIRLLLASGAKVNQPRTGQRP 97
Score = 51.6 bits (118), Expect = 9e-06
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Query: 176 MIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTN-E 234
M+AAY G++D V+ L+ GA ++ + G TAL A++ GH VV +LL HGA +
Sbjct: 1 MVAAYAGHIDCVRELVLQGADINLQREDGGTALLAASQYGHMQVVETLLKHGANIHDQLY 60
Query: 235 NGMTPLQCAAERARASVVEILAA 257
+G T L AA+ V+ +L A
Sbjct: 61 DGATALFLAAQGGYLDVIRLLLA 83
Score = 46.0 bits (104), Expect = 4e-04
Identities = 23/71 (32%), Positives = 39/71 (54%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGAD 163
+G TAL AS GH+ +V+ L+K GA+++ +T L A G LD+++ L+ GA
Sbjct: 28 DGGTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAK 87
Query: 164 IHKANKYNNTC 174
+++ C
Sbjct: 88 VNQPRTGQRPC 98
Score = 32.3 bits (70), Expect = 5.6
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 100 EYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTP 141
+ + +GATAL+ A+ G+L +++ L+ +GA VN RT P
Sbjct: 57 DQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQ-PRTGQRP 97
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 807 RGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 687 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 746
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 747 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 806
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 807 RGADVTLTDNEENICLHWASF 827
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 750 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 809
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 810 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 869
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 870 FLSRGANPELRNKEGDTAWDLTPERS 895
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 824
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 825 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 884
Query: 172 NT 173
+T
Sbjct: 885 DT 886
>AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-13 protein.
Length = 286
Score = 71.7 bits (168), Expect = 8e-12
Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 16/193 (8%)
Query: 46 EIDDLLNIDVCSDGV---KCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYV 102
++ L+ C + V TPL A+ G+ V++LL + D
Sbjct: 42 QLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLA-----------AGAQVDARN 90
Query: 103 IEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
I+G+T L A +G + VK L+ GA VN T S PL AC G + V+ L+ GA
Sbjct: 91 IDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTAS-PLHEACMSGDSECVRLLIDVGA 149
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
++ + + T L +A + +LD V+ LL++GA V+ L TALH AA+ + ++
Sbjct: 150 NLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKL-HETALHHAAKVKNVDLIEM 208
Query: 223 LLDHGAKMLTNEN 235
L++ G + +N
Sbjct: 209 LIEFGGNIYARDN 221
Score = 65.7 bits (153), Expect = 5e-10
Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A+ G +++L+++GA VN T TPL AA +G+ V+ L+ GA + N
Sbjct: 34 AAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDG 93
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKML 231
+T L A G ++ V+ LL GA+V+ L A+ LH A G + V L+D GA +
Sbjct: 94 STPLCDACASGSIECVKLLLSYGAKVNP-PLYTASPLHEACMSGDSECVRLLIDVGANLE 152
Query: 232 TNE-NGMTPLQCAAERARASVVEIL 255
++ + TPL A R V++L
Sbjct: 153 AHDCHFGTPLHVACAREHLDCVKVL 177
Score = 64.9 bits (151), Expect = 9e-10
Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 1/157 (0%)
Query: 99 DEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLV 158
++ ++ T L AS G V+ L+ AGA V+ STPL AC G ++ VK L+
Sbjct: 54 NQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLL 113
Query: 159 RHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAA 218
+GA ++ Y + L A G + V+ L+D GA ++ T LH A H
Sbjct: 114 SYGAKVNPP-LYTASPLHEACMSGDSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLD 172
Query: 219 VVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
V LL+ GA + + T L AA+ ++E+L
Sbjct: 173 CVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEML 209
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/116 (31%), Positives = 55/116 (47%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TP+ A G ++ L+ GA +++ + T L A+ +G VQ LL +GA+VD
Sbjct: 29 TPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDA 88
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEIL 255
R + G+T L A G V LL +GAK+ +PL A + V +L
Sbjct: 89 RNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGDSECVRLL 144
Score = 32.7 bits (71), Expect = 4.3
Identities = 15/35 (42%), Positives = 22/35 (62%)
Query: 530 DVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVA 564
+ C + RLL+D GA+++A D + TPLHVA
Sbjct: 131 EACMSGDSECVRLLIDVGANLEAHDCHFGTPLHVA 165
Score = 31.9 bits (69), Expect = 7.5
Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 13/65 (20%)
Query: 543 LLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLD 602
L++ GA V+ ++ TPLH A + Q A C V LL+ GA VDA ++D
Sbjct: 46 LIESGACVNQVTVDSITPLHAASLQGQ-----------ARC--VQLLLAAGAQVDARNID 92
Query: 603 GITPL 607
G TPL
Sbjct: 93 GSTPL 97
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 71.7 bits (168), Expect = 8e-12
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
T L A+ G + I L++AGA++N + TPL A L++ +Y+V+ G ++
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
+ +TCL AA G L++V LL +G V+ + G T + +AAE H V+ LL
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 226 HGAKM-LTNENGMTPLQCAAERARASVVEIL 255
GA + LT+ L A+ A++ E+L
Sbjct: 598 RGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Score = 69.3 bits (162), Expect = 4e-11
Identities = 47/141 (33%), Positives = 73/141 (51%), Gaps = 3/141 (2%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL AA +G ++I L++ GA+I+ +K T LM A +L+V ++++ G V
Sbjct: 478 TPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYS 537
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKMLT--NENGMTPLQCAAERARASVVEILAA 257
+ G+T LH AA+ G+ +V LL G + + G TP+ AAE V+ +L
Sbjct: 538 KEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLT 597
Query: 258 R-PEVTRAEAIEAYELLGASF 277
R +VT + E L ASF
Sbjct: 598 RGADVTLTDNEENICLHWASF 618
Score = 58.0 bits (134), Expect = 1e-07
Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGA 162
+G+T L A+ G+L +V L+ G DVN TP+ A +++++ L+ GA
Sbjct: 541 DGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGA 600
Query: 163 DIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCS 222
D+ + N CL A++ G + + LL++ + G T LH AA + V
Sbjct: 601 DVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 660
Query: 223 LLDHGAK-MLTNENGMTPLQCAAERA 247
L GA L N+ G T ER+
Sbjct: 661 FLSRGANPELRNKEGDTAWDLTPERS 686
Score = 34.3 bits (75), Expect = 1.4
Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 12/122 (9%)
Query: 53 IDV-CSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
+DV D TP+I AA H +R+LL + + E + L
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENI-----------CLHW 615
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
AS G AI + L+ A D++ TPL A E D V + GA+ NK
Sbjct: 616 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEG 675
Query: 172 NT 173
+T
Sbjct: 676 DT 677
>AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens
cDNA FLJ35245 fis, clone PROST2002897, moderately
similar to Oryctolagus cuniculus CARP mRNA. ).
Length = 263
Score = 71.3 bits (167), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 104 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 163
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 164 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 223
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 224 GAELGVRNAASLTPVQLARDWQR 246
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 169 KYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
K + T L A KG+ +V LL +GA VD R L T + +A GH ++ LL+ GA
Sbjct: 100 KLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGA 159
Query: 229 KMLTNEN-GMTPLQCAAERARASVVEIL 255
++ + G TPL A +E L
Sbjct: 160 RVNARDKIGSTPLHVAVRTRHPDCLEHL 187
>D26069-1|BAA05064.2| 781|Homo sapiens KIAA0041 protein.
Length = 781
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/117 (38%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNN--TCLMIAAYKGYLDVVQFLLDSGARVDD 199
L A +E L + + HGAD++ AN N T L+ A G L +FLL +GA V+
Sbjct: 613 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 672
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
R + G LH A GH VC L GA T+E G PL A E A A +V +L
Sbjct: 673 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 729
Score = 36.7 bits (81), Expect = 0.26
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ AS +L + + GADVN A +TPL A G L ++L+++GA++++
Sbjct: 613 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 672
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ L A G+ V L GA G L A E +A +V L
Sbjct: 673 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 729
>DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein.
Length = 871
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/170 (32%), Positives = 80/170 (47%), Gaps = 16/170 (9%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH +V+ L++ GA VN + L A G + + L+ HGAD+
Sbjct: 78 GNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADV 137
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--------------ATALHF 210
+ N+ + L +A+ G+L VV+ LL++GA VD G TAL
Sbjct: 138 NAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALMA 197
Query: 211 AAECGHAAVVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
A + GH AVV L++ GA G +PL AA R V + L +
Sbjct: 198 AIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEK 247
Score = 70.5 bits (165), Expect = 2e-11
Identities = 56/183 (30%), Positives = 90/183 (49%), Gaps = 8/183 (4%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADIH 165
TAL A GH A+V+ L++ GAD NHA RTV +PL A GRL + + LV GA+
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPD 252
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFL--LDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T +A + D+V +L L + D H A + G+ +V +
Sbjct: 253 HLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFH-ALKMGNFQLVKEI 311
Query: 224 LDHGAK--MLTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEAY-ELLGASFAN 279
D L N +G TPL AA + ++V++L R +V + +++ + L+ A++
Sbjct: 312 ADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHG 371
Query: 280 DKE 282
+KE
Sbjct: 372 NKE 374
Score = 64.1 bits (149), Expect = 2e-09
Identities = 42/117 (35%), Positives = 60/117 (51%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A AG A V A V+ + +T L+ A G +V++L+R GA ++ N Y
Sbjct: 52 AEVAGPGAAAAGAVGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYG 111
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ LM AA G++ V LLD GA V+ + GA+ L A+ GH VV LL+ GA
Sbjct: 112 WSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGA 168
Score = 52.0 bits (119), Expect = 7e-06
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Query: 116 GHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-T 173
G+ +VK + + VN +TPL A G+L +V+ LV AD+ K + + T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
LM A Y G ++V++LL+ GA V RA G TA
Sbjct: 363 ALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTA 396
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGA 162
+GAT L A+ G LA+V+ LV+ ADV+ T L A + G +IVKYL+ GA
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGA 384
Query: 163 DI 164
D+
Sbjct: 385 DV 386
Score = 40.3 bits (90), Expect = 0.021
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 14/197 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L+ A +HG E VR+L+E P TV G + L A+ G L + +
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPN--HAARTV--------GWSPLMLAALTGRLGVAQ 242
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK- 181
+LV+ GA+ +H + T A D+V YL K ++ + A K
Sbjct: 243 QLVEKGANPDHLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFHALKM 302
Query: 182 GYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE--NGMT 238
G +V+ + D + V+ GAT L AA G A+V L++ A + + +G T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 239 PLQCAAERARASVVEIL 255
L A +V+ L
Sbjct: 363 ALMQATYHGNKEIVKYL 379
Score = 33.5 bits (73), Expect = 2.4
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 197 VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
VD G TAL FAA GH +V LL GA + + N G + L AA SV +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
>BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 23
protein.
Length = 305
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 265
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 266 GAELGVRNAASVTPVQLARDWQR 288
Score = 55.6 bits (128), Expect = 5e-07
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
++ + + G D N + T L AC +G +V L+ GA + + + T + A
Sbjct: 126 LIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWAC 185
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+L +++ LL+ GARV+ R G+T LH A H + L++ GA + ++ G T
Sbjct: 186 RGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDT 245
Query: 239 PLQCAAERARASVVEIL 255
L A +++L
Sbjct: 246 ALHEAVRHGSYKAMKLL 262
Score = 54.8 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRA 201
L+AA I KYL G D + +K + T L A KG+ +V LL +GA VD R
Sbjct: 116 LKAAAENQEYLIDKYLT-DGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARD 174
Query: 202 LCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
L T + +A GH ++ LL+ GA++ + G TPL A +E L
Sbjct: 175 LLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL 229
>BC060767-1|AAH60767.1| 778|Homo sapiens centaurin, beta 2 protein.
Length = 778
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/117 (38%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNN--TCLMIAAYKGYLDVVQFLLDSGARVDD 199
L A +E L + + HGAD++ AN N T L+ A G L +FLL +GA V+
Sbjct: 610 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 669
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
R + G LH A GH VC L GA T+E G PL A E A A +V +L
Sbjct: 670 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 726
Score = 36.7 bits (81), Expect = 0.26
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ AS +L + + GADVN A +TPL A G L ++L+++GA++++
Sbjct: 610 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 669
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ L A G+ V L GA G L A E +A +V L
Sbjct: 670 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 726
>BC031005-1|AAH31005.1| 201|Homo sapiens Similar to centaurin, beta
2 protein.
Length = 201
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/117 (38%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNN--TCLMIAAYKGYLDVVQFLLDSGARVDD 199
L A +E L + + HGAD++ AN N T L+ A G L +FLL +GA V+
Sbjct: 33 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 92
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
R + G LH A GH VC L GA T+E G PL A E A A +V +L
Sbjct: 93 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 149
Score = 36.7 bits (81), Expect = 0.26
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ AS +L + + GADVN A +TPL A G L ++L+++GA++++
Sbjct: 33 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 92
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ L A G+ V L GA G L A E +A +V L
Sbjct: 93 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 149
>BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor-li
protein.
Length = 1219
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Query: 126 KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLD 185
+ G+ N T L AC EG+L V+ LVR G ++ + T L A G+L+
Sbjct: 358 RKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLE 417
Query: 186 VVQFLLDSGARVDD---RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+V+FLLD GA VDD + G T LH A CGH V LL+ GA + L G++PL+
Sbjct: 418 IVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPLE 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/107 (34%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A G L V+ LV+ G +N TPL AC G L+IV++L+ HGA +
Sbjct: 370 GETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAV 429
Query: 165 HKANKY---NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
T L A G+ +V + LL+ GA V R G + L
Sbjct: 430 DDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPL 476
>AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat
protein 3 protein.
Length = 305
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 265
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 266 GAELGVRNAASVTPVQLARDWQR 288
Score = 55.6 bits (128), Expect = 5e-07
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
++ + + G D N + T L AC +G +V L+ GA + + + T + A
Sbjct: 126 LIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWAC 185
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+L +++ LL+ GARV+ R G+T LH A H + L++ GA + ++ G T
Sbjct: 186 RGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDT 245
Query: 239 PLQCAAERARASVVEIL 255
L A +++L
Sbjct: 246 ALHEAVRHGSYKAMKLL 262
Score = 54.8 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRA 201
L+AA I KYL G D + +K + T L A KG+ +V LL +GA VD R
Sbjct: 116 LKAAAENQEYLIDKYLT-DGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARD 174
Query: 202 LCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
L T + +A GH ++ LL+ GA++ + G TPL A +E L
Sbjct: 175 LLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL 229
>AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/170 (32%), Positives = 80/170 (47%), Gaps = 16/170 (9%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH +V+ L++ GA VN + L A G + + L+ HGAD+
Sbjct: 78 GNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADV 137
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--------------ATALHF 210
+ N+ + L +A+ G+L VV+ LL++GA VD G TAL
Sbjct: 138 NAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALMA 197
Query: 211 AAECGHAAVVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
A + GH AVV L++ GA G +PL AA R V + L +
Sbjct: 198 AIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEK 247
Score = 70.5 bits (165), Expect = 2e-11
Identities = 56/183 (30%), Positives = 90/183 (49%), Gaps = 8/183 (4%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADIH 165
TAL A GH A+V+ L++ GAD NHA RTV +PL A GRL + + LV GA+
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPD 252
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFL--LDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T +A + D+V +L L + D H A + G+ +V +
Sbjct: 253 HLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFH-ALKMGNFQLVKEI 311
Query: 224 LDHGAK--MLTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEAY-ELLGASFAN 279
D L N +G TPL AA + ++V++L R +V + +++ + L+ A++
Sbjct: 312 ADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHG 371
Query: 280 DKE 282
+KE
Sbjct: 372 NKE 374
Score = 64.1 bits (149), Expect = 2e-09
Identities = 42/117 (35%), Positives = 60/117 (51%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A AG A V A V+ + +T L+ A G +V++L+R GA ++ N Y
Sbjct: 52 AEVAGPGAAAAGAVGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYG 111
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ LM AA G++ V LLD GA V+ + GA+ L A+ GH VV LL+ GA
Sbjct: 112 WSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGA 168
Score = 52.0 bits (119), Expect = 7e-06
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Query: 116 GHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-T 173
G+ +VK + + VN +TPL A G+L +V+ LV AD+ K + + T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
LM A Y G ++V++LL+ GA V RA G TA
Sbjct: 363 ALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTA 396
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGA 162
+GAT L A+ G LA+V+ LV+ ADV+ T L A + G +IVKYL+ GA
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGA 384
Query: 163 DI 164
D+
Sbjct: 385 DV 386
Score = 40.3 bits (90), Expect = 0.021
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 14/197 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L+ A +HG E VR+L+E P TV G + L A+ G L + +
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPN--HAARTV--------GWSPLMLAALTGRLGVAQ 242
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK- 181
+LV+ GA+ +H + T A D+V YL K ++ + A K
Sbjct: 243 QLVEKGANPDHLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFHALKM 302
Query: 182 GYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE--NGMT 238
G +V+ + D + V+ GAT L AA G A+V L++ A + + +G T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 239 PLQCAAERARASVVEIL 255
L A +V+ L
Sbjct: 363 ALMQATYHGNKEIVKYL 379
Score = 33.5 bits (73), Expect = 2.4
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 197 VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
VD G TAL FAA GH +V LL GA + + N G + L AA SV +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
>AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/170 (32%), Positives = 80/170 (47%), Gaps = 16/170 (9%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G TAL A+ GH +V+ L++ GA VN + L A G + + L+ HGAD+
Sbjct: 78 GNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADV 137
Query: 165 HKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCG--------------ATALHF 210
+ N+ + L +A+ G+L VV+ LL++GA VD G TAL
Sbjct: 138 NAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALMA 197
Query: 211 AAECGHAAVVCSLLDHGA--KMLTNENGMTPLQCAAERARASVVEILAAR 258
A + GH AVV L++ GA G +PL AA R V + L +
Sbjct: 198 AIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEK 247
Score = 70.5 bits (165), Expect = 2e-11
Identities = 56/183 (30%), Positives = 90/183 (49%), Gaps = 8/183 (4%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGADIH 165
TAL A GH A+V+ L++ GAD NHA RTV +PL A GRL + + LV GA+
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPD 252
Query: 166 KANKYNNTCLMIAAYKGYLDVVQFL--LDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ T +A + D+V +L L + D H A + G+ +V +
Sbjct: 253 HLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFH-ALKMGNFQLVKEI 311
Query: 224 LDHGAK--MLTNENGMTPLQCAAERARASVVEILAAR-PEVTRAEAIEAY-ELLGASFAN 279
D L N +G TPL AA + ++V++L R +V + +++ + L+ A++
Sbjct: 312 ADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHG 371
Query: 280 DKE 282
+KE
Sbjct: 372 NKE 374
Score = 64.1 bits (149), Expect = 2e-09
Identities = 42/117 (35%), Positives = 60/117 (51%)
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYN 171
A AG A V A V+ + +T L+ A G +V++L+R GA ++ N Y
Sbjct: 52 AEVAGPGAAAAGAVGAPVPVDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYG 111
Query: 172 NTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ LM AA G++ V LLD GA V+ + GA+ L A+ GH VV LL+ GA
Sbjct: 112 WSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGA 168
Score = 52.0 bits (119), Expect = 7e-06
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Query: 116 GHLAIVKRLVKAG-ADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNN-T 173
G+ +VK + + VN +TPL A G+L +V+ LV AD+ K + + T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 174 CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATA 207
LM A Y G ++V++LL+ GA V RA G TA
Sbjct: 363 ALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTA 396
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 104 EGATALWCASGAGHLAIVKRLVKAGADVNHATRTVS-TPLRAACFEGRLDIVKYLVRHGA 162
+GAT L A+ G LA+V+ LV+ ADV+ T L A + G +IVKYL+ GA
Sbjct: 325 DGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGA 384
Query: 163 DI 164
D+
Sbjct: 385 DV 386
Score = 40.3 bits (90), Expect = 0.021
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 14/197 (7%)
Query: 63 TPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVK 122
T L+ A +HG E VR+L+E P TV G + L A+ G L + +
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPN--HAARTV--------GWSPLMLAALTGRLGVAQ 242
Query: 123 RLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYK- 181
+LV+ GA+ +H + T A D+V YL K ++ + A K
Sbjct: 243 QLVEKGANPDHLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFHALKM 302
Query: 182 GYLDVVQFLLDSG-ARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNE--NGMT 238
G +V+ + D + V+ GAT L AA G A+V L++ A + + +G T
Sbjct: 303 GNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWT 362
Query: 239 PLQCAAERARASVVEIL 255
L A +V+ L
Sbjct: 363 ALMQATYHGNKEIVKYL 379
Score = 33.5 bits (73), Expect = 2.4
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 197 VDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT-NENGMTPLQCAAERARASVVEIL 255
VD G TAL FAA GH +V LL GA + + N G + L AA SV +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
>AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containing
protein protein.
Length = 296
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 137 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 196
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 197 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 256
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 257 GAELGVRNAASVTPVQLARDWQR 279
Score = 55.6 bits (128), Expect = 5e-07
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
++ + + G D N + T L AC +G +V L+ GA + + + T + A
Sbjct: 117 LIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWAC 176
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+L +++ LL+ GARV+ R G+T LH A H + L++ GA + ++ G T
Sbjct: 177 RGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDT 236
Query: 239 PLQCAAERARASVVEIL 255
L A +++L
Sbjct: 237 ALHEAVRHGSYKAMKLL 253
Score = 54.8 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRA 201
L+AA I KYL G D + +K + T L A KG+ +V LL +GA VD R
Sbjct: 107 LKAAAENQEYLIDKYLT-DGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARD 165
Query: 202 LCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
L T + +A GH ++ LL+ GA++ + G TPL A +E L
Sbjct: 166 LLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL 220
>AJ249601-1|CAB63467.1| 559|Homo sapiens IkappaBR protein.
Length = 559
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Query: 126 KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLD 185
+ G+ N T L AC EG+L V+ LVR G ++ + T L A G+L+
Sbjct: 358 RKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLE 417
Query: 186 VVQFLLDSGARVDD---RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+V+FLLD GA VDD + G T LH A CGH V LL+ GA + L G++PL+
Sbjct: 418 IVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPLE 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/107 (34%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A G L V+ LV+ G +N TPL AC G L+IV++L+ HGA +
Sbjct: 370 GETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAV 429
Query: 165 HKANKY---NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
T L A G+ +V + LL+ GA V R G + L
Sbjct: 430 DDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPL 476
>AJ238248-1|CAB41450.1| 778|Homo sapiens centaurin beta2 protein.
Length = 778
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/117 (38%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNN--TCLMIAAYKGYLDVVQFLLDSGARVDD 199
L A +E L + + HGAD++ AN N T L+ A G L +FLL +GA V+
Sbjct: 610 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 669
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQCAAERARASVVEIL 255
R + G LH A GH VC L GA T+E G PL A E A A +V +L
Sbjct: 670 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 726
Score = 36.7 bits (81), Expect = 0.26
Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Query: 109 LWCASGAGHLAIVKRLVKAGADVNHAT--RTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
L+ AS +L + + GADVN A +TPL A G L ++L+++GA++++
Sbjct: 610 LYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQ 669
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSL 223
+ L A G+ V L GA G L A E +A +V L
Sbjct: 670 RDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLL 726
>AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyrin
repeat protein protein.
Length = 305
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 265
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 266 GAELGVRNAASVTPVQLARDWQR 288
Score = 55.6 bits (128), Expect = 5e-07
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
++ + + G D N + T L AC +G +V L+ GA + + + T + A
Sbjct: 126 LIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWAC 185
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+L +++ LL+ GARV+ R G+T LH A H + L++ GA + ++ G T
Sbjct: 186 RGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDT 245
Query: 239 PLQCAAERARASVVEIL 255
L A +++L
Sbjct: 246 ALHEAVRHGSYKAMKLL 262
Score = 54.8 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRA 201
L+AA I KYL G D + +K + T L A KG+ +V LL +GA VD R
Sbjct: 116 LKAAAENQEYLIDKYLT-DGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARD 174
Query: 202 LCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
L T + +A GH ++ LL+ GA++ + G TPL A +E L
Sbjct: 175 LLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL 229
>AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein.
Length = 305
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 1/143 (0%)
Query: 107 TALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK 166
TAL A GH +V +L+ AGA V+ TP+ AC G L I+K L+ GA ++
Sbjct: 146 TALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNA 205
Query: 167 ANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDH 226
+K +T L +A + D ++ L++ GA ++ + G TALH A G + LL +
Sbjct: 206 RDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLY 265
Query: 227 GAKM-LTNENGMTPLQCAAERAR 248
GA++ + N +TP+Q A + R
Sbjct: 266 GAELGVRNAASVTPVQLARDWQR 288
Score = 55.6 bits (128), Expect = 5e-07
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%)
Query: 120 IVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAA 179
++ + + G D N + T L AC +G +V L+ GA + + + T + A
Sbjct: 126 LIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWAC 185
Query: 180 YKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMT 238
G+L +++ LL+ GARV+ R G+T LH A H + L++ GA + ++ G T
Sbjct: 186 RGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDT 245
Query: 239 PLQCAAERARASVVEIL 255
L A +++L
Sbjct: 246 ALHEAVRHGSYKAMKLL 262
Score = 54.8 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Query: 142 LRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRA 201
L+AA I KYL G D + +K + T L A KG+ +V LL +GA VD R
Sbjct: 116 LKAAAENQEYLIDKYLT-DGGDPNAHDKLHRTALHWACLKGHSQLVNKLLVAGATVDARD 174
Query: 202 LCGATALHFAAECGHAAVVCSLLDHGAKMLTNEN-GMTPLQCAAERARASVVEIL 255
L T + +A GH ++ LL+ GA++ + G TPL A +E L
Sbjct: 175 LLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL 229
>AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 70.9 bits (166), Expect = 1e-11
Identities = 64/199 (32%), Positives = 90/199 (45%), Gaps = 20/199 (10%)
Query: 59 GVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHL 118
G +PL AA +G A+ +LL+ V L+ DE +G TAL A+ GH
Sbjct: 15 GATKSPLHLAAYNGHHQALEVLLQSL---VDLDIR-----DE---KGRTALDLAAFKGHT 63
Query: 119 AIVKRLVKAGADVNHATR-TVSTPLRAACFEGRLDIVKYLVR-----HGADIHKANKYNN 172
V+ L+ GA + T TPL A+ G ++ L+ D+ A
Sbjct: 64 ECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAK--GQ 121
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T LM+A G++D V LL+ A VD + G TALH GH V LL+ +L
Sbjct: 122 TPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILC 181
Query: 233 NEN-GMTPLQCAAERARAS 250
++ G TPL AA R A+
Sbjct: 182 KDSRGRTPLHYAAARGHAT 200
Score = 52.4 bits (120), Expect = 5e-06
Identities = 52/178 (29%), Positives = 75/178 (42%), Gaps = 20/178 (11%)
Query: 54 DVC-SDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCA 112
D C D TPL A +G E + +LLE+ C F +++ T L CA
Sbjct: 214 DCCFKDNQGYTPLHWACYNGNENCIEVLLEQ----KC--------FRKFIGNPFTPLHCA 261
Query: 113 SGAGHLAIVKRLVKA--GADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKY 170
H L+ A + V+ TPL AA F ++ ++ L+RH A ++ +
Sbjct: 262 IINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNS 321
Query: 171 NNTCLMIAAYKGYLDVVQFLLDSG---ARVDDRALCGATALHFAAECGHAAVVCSLLD 225
T LM+AA G V L++S V D+ L T LH A GH +LD
Sbjct: 322 GKTALMMAAENGQAGAVDILVNSAQADLTVKDKDL--NTPLHLACSKGHEKCALLILD 377
Score = 48.8 bits (111), Expect = 6e-05
Identities = 56/208 (26%), Positives = 85/208 (40%), Gaps = 15/208 (7%)
Query: 52 NIDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWC 111
N+D D + CT L G E V++LLE+ +C ++ G Y A W
Sbjct: 145 NVDTV-DILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPL-HYAAARGHATW- 201
Query: 112 ASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHK--ANK 169
L+ + ++ + D TPL AC+ G + ++ L+ K N
Sbjct: 202 ------LSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC-FRKFIGNP 254
Query: 170 YNNT-CLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGA 228
+ C +I + ++ +DS V R G T LH AA H + LL H A
Sbjct: 255 FTPLHCAIINDHGNCASLLLGAIDSSI-VSCRDDKGRTPLHAAAFADHVECLQLLLRHSA 313
Query: 229 KMLTNEN-GMTPLQCAAERARASVVEIL 255
+ +N G T L AAE +A V+IL
Sbjct: 314 PVNAVDNSGKTALMMAAENGQAGAVDIL 341
Score = 48.4 bits (110), Expect = 8e-05
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
TPL A G +D V L+ A++ + T L G+ + VQ LL+ +
Sbjct: 122 TPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILC 181
Query: 200 RALCGATALHFAAECGHAAVVCSLLDHGAK----MLTNENGMTPLQCAAERARASVVEIL 255
+ G T LH+AA GHA + LL + G TPL A + +E+L
Sbjct: 182 KDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVL 241
Score = 43.2 bits (97), Expect = 0.003
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 5/121 (4%)
Query: 140 TPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDD 199
+PL A + G ++ L++ D+ ++ T L +AA+KG+ + V+ L++ GA +
Sbjct: 19 SPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFV 78
Query: 200 R-ALCGATALHFAAECGHAAVVCSLLDHG----AKMLTNENGMTPLQCAAERARASVVEI 254
+ + T LH + GH + LL+ A + + G TPL A V +
Sbjct: 79 KDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSL 138
Query: 255 L 255
L
Sbjct: 139 L 139
Score = 33.1 bits (72), Expect = 3.2
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 173 TCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLT 232
T L AA+ +++ +Q LL A V+ G TAL AAE G A V L++ LT
Sbjct: 291 TPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLT 350
Query: 233 --NENGMTPLQCAAER 246
+++ TPL A +
Sbjct: 351 VKDKDLNTPLHLACSK 366
>AB209126-1|BAD92363.1| 897|Homo sapiens I-kappa-B-related protein
variant protein.
Length = 897
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 4/120 (3%)
Query: 126 KAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLD 185
+ G+ N T L AC EG+L V+ LVR G ++ + T L A G+L+
Sbjct: 217 RKGSKWNRRNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLE 276
Query: 186 VVQFLLDSGARVDD---RALCGATALHFAAECGHAAVVCSLLDHGAKM-LTNENGMTPLQ 241
+V+FLLD GA VDD + G T LH A CGH V LL+ GA + L G++PL+
Sbjct: 277 IVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPLE 336
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/107 (34%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Query: 105 GATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADI 164
G T L A G L V+ LV+ G +N TPL AC G L+IV++L+ HGA +
Sbjct: 229 GETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLHEACNYGHLEIVRFLLDHGAAV 288
Query: 165 HKANKY---NNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATAL 208
T L A G+ +V + LL+ GA V R G + L
Sbjct: 289 DDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVTLRTRKGLSPL 335
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.137 0.412
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,114,084
Number of Sequences: 224733
Number of extensions: 3763881
Number of successful extensions: 21275
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 879
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 9908
Number of HSP's gapped (non-prelim): 7487
length of query: 664
length of database: 73,234,838
effective HSP length: 95
effective length of query: 569
effective length of database: 51,885,203
effective search space: 29522680507
effective search space used: 29522680507
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 68 (31.5 bits)
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