Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001965-TA|BGIBMGA001965-PA|IPR002086|Aldehyde
dehydrogenase, IPR012394|Aldehyde dehydrogenase NAD(P)-dependent
(440 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U10868-1|AAA83428.1| 468|Homo sapiens ALDH7 protein. 395 e-109
EF411198-1|ABN58743.1| 468|Homo sapiens aldehyde dehydrogenase ... 395 e-109
BT009832-1|AAP88834.1| 468|Homo sapiens aldehyde dehydrogenase ... 395 e-109
BC013584-1|AAH13584.1| 468|Homo sapiens aldehyde dehydrogenase ... 395 e-109
U75296-1|AAC50966.1| 485|Homo sapiens fatty aldehyde dehydrogen... 392 e-108
U75295-1|AAC50965.1| 508|Homo sapiens fatty aldehyde dehydrogen... 392 e-108
U46689-1|AAC51121.1| 485|Homo sapiens aldehyde dehydrogenase pr... 392 e-108
L47162-1|AAB01003.1| 485|Homo sapiens fatty aldehyde dehydrogen... 392 e-108
CR457422-1|CAG33703.1| 485|Homo sapiens ALDH3A2 protein. 392 e-108
BC002430-1|AAH02430.1| 508|Homo sapiens aldehyde dehydrogenase ... 392 e-108
M74542-1|AAA51696.1| 453|Homo sapiens aldehyde dehydrogenase ty... 391 e-108
BT007102-1|AAP35766.1| 453|Homo sapiens aldehyde dehydrogenase ... 391 e-108
BC021194-1|AAH21194.1| 453|Homo sapiens aldehyde dehydrogenase ... 391 e-108
BC008892-1|AAH08892.1| 453|Homo sapiens aldehyde dehydrogenase ... 391 e-108
BC004370-1|AAH04370.1| 453|Homo sapiens aldehyde dehydrogenase ... 391 e-108
S61044-1|AAB26658.1| 453|Homo sapiens aldehyde dehydrogenase is... 388 e-107
M77477-1|AAB46377.1| 453|Homo sapiens aldehyde dehydrogenase pr... 388 e-107
BC004102-1|AAH04102.1| 512|Homo sapiens ALDH3A1 protein protein. 381 e-105
AB208894-1|BAD92131.1| 461|Homo sapiens aldehyde dehydrogenase ... 376 e-104
AB209651-1|BAD92888.1| 447|Homo sapiens aldehyde dehydrogenase ... 360 6e-99
BC033099-1|AAH33099.1| 431|Homo sapiens aldehyde dehydrogenase ... 342 1e-93
BT006810-1|AAP35456.1| 385|Homo sapiens aldehyde dehydrogenase ... 326 7e-89
BC007685-1|AAH07685.1| 385|Homo sapiens aldehyde dehydrogenase ... 326 7e-89
U37519-1|AAA85441.1| 385|Homo sapiens aldehyde dehydrogenase pr... 326 9e-89
AK092464-1|BAC03897.1| 385|Homo sapiens protein ( Homo sapiens ... 326 9e-89
AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens ... 303 1e-81
BC002553-1|AAH02553.1| 230|Homo sapiens ALDH3B1 protein protein. 194 7e-49
U07919-1|AAA79036.1| 512|Homo sapiens aldehyde dehydrogenase 6 ... 145 2e-34
DQ322171-1|ABC40749.1| 518|Homo sapiens aldehyde dehydrogenase ... 145 2e-34
BC069274-1|AAH69274.1| 512|Homo sapiens aldehyde dehydrogenase ... 145 2e-34
AB015228-1|BAA34787.1| 422|Homo sapiens RALDH2-T protein. 145 2e-34
AB015227-1|BAA34786.1| 422|Homo sapiens RALDH2-T protein. 145 2e-34
AB015226-1|BAA34785.1| 518|Homo sapiens RALDH2 protein. 145 2e-34
M31994-1|AAA51692.1| 501|Homo sapiens aldehyde dehydrogenase pr... 137 6e-32
BT006921-1|AAP35567.1| 501|Homo sapiens aldehyde dehydrogenase ... 137 6e-32
BC001505-1|AAH01505.1| 501|Homo sapiens aldehyde dehydrogenase ... 137 6e-32
AY390731-1|AAR92229.1| 501|Homo sapiens aldehyde dehydrogenase ... 137 6e-32
AY338497-1|AAP88039.1| 501|Homo sapiens aldehyde dehydrogenase ... 137 6e-32
AL591031-1|CAI12257.1| 501|Homo sapiens aldehyde dehydrogenase ... 137 6e-32
AF003341-1|AAC51652.1| 501|Homo sapiens aldehyde dehydrogenase ... 136 1e-31
M26761-1|AAA35518.1| 340|Homo sapiens aldehyde dehydrogenase I ... 130 1e-29
K03000-1|AAA51695.1| 340|Homo sapiens ALDH1 protein. 130 1e-29
AY621070-1|AAT41621.1| 517|Homo sapiens mitochondrial aldehyde ... 129 2e-29
M20456-1|AAA51693.1| 517|Homo sapiens aldehyde dehydrogenase pr... 128 3e-29
BC071839-1|AAH71839.1| 517|Homo sapiens aldehyde dehydrogenase ... 128 3e-29
BC002967-1|AAH02967.1| 517|Homo sapiens aldehyde dehydrogenase ... 128 3e-29
AK223373-1|BAD97093.1| 517|Homo sapiens mitochondrial aldehyde ... 128 3e-29
Y00109-1|CAA68290.1| 515|Homo sapiens protein ( Human mRNA for ... 127 7e-29
X05409-1|CAA28990.1| 516|Homo sapiens protein ( Human RNA for m... 127 7e-29
CR456991-1|CAG33272.1| 517|Homo sapiens ALDH2 protein. 127 7e-29
M26760-1|AAA51694.1| 399|Homo sapiens aldehyde dehydrogenase II... 126 2e-28
K03001-1|AAB59500.1| 399|Homo sapiens ALDH2 protein. 126 2e-28
AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase ... 126 2e-28
M63967-1|AAA96830.1| 517|Homo sapiens aldehyde dehydrogenase pr... 126 2e-28
BT007418-1|AAP36086.1| 517|Homo sapiens aldehyde dehydrogenase ... 126 2e-28
BC001619-1|AAH01619.1| 517|Homo sapiens aldehyde dehydrogenase ... 126 2e-28
U50203-1|AAB06721.1| 466|Homo sapiens aldehyde dehydrogenase E3... 124 8e-28
U34252-1|AAB18827.1| 493|Homo sapiens gamma-aminobutyraldehyde ... 124 8e-28
AL451074-5|CAH74061.1| 518|Homo sapiens aldehyde dehydrogenase ... 124 8e-28
AF172093-1|AAF43600.1| 494|Homo sapiens 4-trimethylaminobutyral... 124 8e-28
X75425-1|CAA53176.1| 462|Homo sapiens aldehyde dehydrogenase (N... 122 3e-27
BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase ... 119 2e-26
Y11192-1|CAA72076.1| 535|Homo sapiens succinic semialdehyde deh... 115 3e-25
BC034321-1|AAH34321.1| 535|Homo sapiens aldehyde dehydrogenase ... 115 3e-25
AL031230-4|CAA20248.1| 535|Homo sapiens aldehyde dehydrogenase ... 115 3e-25
AJ427355-1|CAD20884.1| 535|Homo sapiens succinic semialdehyde d... 115 3e-25
BC113862-1|AAI13863.1| 487|Homo sapiens aldehyde dehydrogenase ... 113 1e-24
AL445190-1|CAI95158.1| 487|Homo sapiens aldehyde dehydrogenase ... 113 1e-24
AL021939-1|CAI20305.1| 487|Homo sapiens aldehyde dehydrogenase ... 113 1e-24
AF303134-1|AAG42417.1| 487|Homo sapiens aldehyde dehydrogenase ... 113 1e-24
AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate ... 110 8e-24
AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate ... 110 8e-24
AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase ... 110 1e-23
AJ427354-1|CAD20883.2| 480|Homo sapiens succinic semialdehyde d... 109 1e-23
BX538027-1|CAD97973.1| 416|Homo sapiens hypothetical protein pr... 106 1e-22
AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofola... 106 2e-22
AB209821-1|BAD93058.1| 330|Homo sapiens aldehyde dehydrogenase ... 105 3e-22
BC103935-1|AAI03936.1| 488|Homo sapiens ALDH1L2 protein protein. 97 8e-20
AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens ... 97 8e-20
L34820-1|AAA67057.1| 323|Homo sapiens succinate semialdehyde de... 97 1e-19
BC030589-1|AAH30589.1| 480|Homo sapiens aldehyde dehydrogenase ... 91 5e-18
M93405-1|AAA36328.1| 430|Homo sapiens methylmalonate semialdehy... 90 2e-17
BC032371-1|AAH32371.1| 535|Homo sapiens aldehyde dehydrogenase ... 90 2e-17
BC004909-1|AAH04909.1| 535|Homo sapiens aldehyde dehydrogenase ... 90 2e-17
AJ249994-1|CAB76468.1| 535|Homo sapiens methylmalonate semialde... 90 2e-17
AF159889-1|AAF80380.1| 535|Homo sapiens methylmalonate semialde... 90 2e-17
AF148855-1|AAG29581.1| 535|Homo sapiens methylmalonate-semialde... 90 2e-17
AF148505-1|AAF04489.1| 535|Homo sapiens methylmalonate-semialde... 90 2e-17
AK222687-1|BAD96407.1| 535|Homo sapiens aldehyde dehydrogenase ... 89 3e-17
AK223244-1|BAD96964.1| 535|Homo sapiens aldehyde dehydrogenase ... 87 9e-17
M54931-1|AAA62825.1| 287|Homo sapiens aldehyde dehydrogenase I ... 87 2e-16
BC014168-1|AAH14168.2| 159|Homo sapiens ALDH3B1 protein protein. 83 2e-15
AL445190-2|CAI95159.1| 433|Homo sapiens aldehyde dehydrogenase ... 82 3e-15
AL021939-2|CAI20306.1| 433|Homo sapiens aldehyde dehydrogenase ... 82 3e-15
AK222848-1|BAD96568.1| 433|Homo sapiens aldehyde dehydrogenase ... 79 2e-14
S74728-1|AAB31966.1| 511|Homo sapiens antiquitin protein. 77 1e-13
BC073174-1|AAH73174.1| 511|Homo sapiens aldehyde dehydrogenase ... 77 1e-13
BC071712-1|AAH71712.1| 511|Homo sapiens aldehyde dehydrogenase ... 77 1e-13
BC002515-1|AAH02515.3| 511|Homo sapiens aldehyde dehydrogenase ... 75 4e-13
BC070030-1|AAH70030.1| 253|Homo sapiens ALDH9A1 protein protein. 65 5e-10
BC114473-1|AAI14474.1| 265|Homo sapiens ALDH8A1 protein protein. 61 9e-09
BC007581-1|AAH07581.1| 563|Homo sapiens aldehyde dehydrogenase ... 61 9e-09
U24267-1|AAC50501.1| 563|Homo sapiens pyrroline-5-carboxylate d... 60 1e-08
U24266-1|AAC50500.1| 563|Homo sapiens pyrroline-5-carboxylate d... 60 1e-08
BC023600-1|AAH23600.1| 563|Homo sapiens aldehyde dehydrogenase ... 60 1e-08
AL954340-2|CAI39493.1| 563|Homo sapiens aldehyde dehydrogenase ... 60 1e-08
AL080251-1|CAI23417.1| 563|Homo sapiens aldehyde dehydrogenase ... 60 1e-08
AK222486-1|BAD96206.1| 563|Homo sapiens aldehyde dehydrogenase ... 60 1e-08
AK124908-1|BAC85992.1| 470|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AL591031-3|CAI12260.1| 238|Homo sapiens aldehyde dehydrogenase ... 52 5e-06
AL591031-2|CAI12259.1| 230|Homo sapiens aldehyde dehydrogenase ... 50 2e-05
AJ427353-1|CAD20882.1| 222|Homo sapiens succinate semialdehyde ... 49 3e-05
AL591031-4|CAI12261.1| 203|Homo sapiens aldehyde dehydrogenase ... 48 5e-05
BC042142-1|AAH42142.1| 481|Homo sapiens ALDH16A1 protein protein. 42 0.004
BC035641-1|AAH35641.1| 216|Homo sapiens ALDH16A1 protein protein. 42 0.004
BC014895-1|AAH14895.2| 802|Homo sapiens aldehyde dehydrogenase ... 42 0.004
AK124965-1|BAC86008.1| 131|Homo sapiens protein ( Homo sapiens ... 41 0.010
AJ567755-1|CAD99005.1| 162|Homo sapiens KI67 Antigen protein. 33 2.0
BC112121-1|AAI12122.1| 478|Homo sapiens growth arrest-specific ... 32 4.6
BC104785-1|AAI04786.1| 478|Homo sapiens growth arrest-specific ... 32 4.6
AF077611-1|AAC27787.1| 193|Homo sapiens interleukin-18 precurso... 32 4.6
AF050079-1|AAC69519.1| 478|Homo sapiens growth arrest specific ... 32 4.6
AF050078-1|AAC69518.1| 478|Homo sapiens growth arrest specific ... 32 4.6
U90434-1|AAB50010.1| 192|Homo sapiens interferon-gamma inducing... 31 6.1
D49950-1|BAA08706.1| 193|Homo sapiens interferon-gamma inducing... 31 6.1
CR542001-1|CAG46798.1| 193|Homo sapiens IL18 protein. 31 6.1
CR541973-1|CAG46771.1| 193|Homo sapiens IL18 protein. 31 6.1
BC007461-1|AAH07461.1| 193|Homo sapiens interleukin 18 (interfe... 31 6.1
BC007007-1|AAH07007.1| 193|Homo sapiens interleukin 18 (interfe... 31 6.1
AY044641-1|AAK95950.1| 193|Homo sapiens interleukin 18 protein. 31 6.1
AF219939-1|AAF43006.1| 931|Homo sapiens diacylglycerol kinase i... 31 6.1
AF061936-1|AAC62010.1| 1065|Homo sapiens diacylglycerol kinase i... 31 6.1
AB209167-1|BAD92404.1| 871|Homo sapiens diacylglycerol kinase, ... 31 6.1
>U10868-1|AAA83428.1| 468|Homo sapiens ALDH7 protein.
Length = 468
Score = 395 bits (973), Expect = e-109
Identities = 180/385 (46%), Positives = 264/385 (68%), Gaps = 2/385 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL +S ES + E+
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
+ ++ L NL +W K ER ++ LD FI +P+G+VLII WNYPL L+L+P+ G
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVG 127
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
A+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET +LL HRFDYIF+T
Sbjct: 128 ALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFT 187
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
GS +GKI+ +AAKHLTPVTLELGGK+P Y+DD D + +R+ W ++ NAGQTC+AP
Sbjct: 188 GSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAP 247
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DYVLC+ E+QE+ + + + +++GDDPQ +P+ RI+N + F RL+A+L R +AI
Sbjct: 248 DYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR--VAI 305
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D D++I T+L +V + +M++EIFGP+L I V+ ++EA++FIN R KPL LY
Sbjct: 306 GGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALY 365
Query: 408 VFSSSEKVHKIFASHTSSGSICFND 432
FS+S +V K + TSSG C ND
Sbjct: 366 AFSNSSQVVKRVLTQTSSGGFCGND 390
>EF411198-1|ABN58743.1| 468|Homo sapiens aldehyde dehydrogenase 3B1
protein.
Length = 468
Score = 395 bits (973), Expect = e-109
Identities = 180/385 (46%), Positives = 264/385 (68%), Gaps = 2/385 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL +S ES + E+
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
+ ++ L NL +W K ER ++ LD FI +P+G+VLII WNYPL L+L+P+ G
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVG 127
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
A+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET +LL HRFDYIF+T
Sbjct: 128 ALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFT 187
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
GS +GKI+ +AAKHLTPVTLELGGK+P Y+DD D + +R+ W ++ NAGQTC+AP
Sbjct: 188 GSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAP 247
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DYVLC+ E+QE+ + + + +++GDDPQ +P+ RI+N + F RL+A+L R +AI
Sbjct: 248 DYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR--VAI 305
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D D++I T+L +V + +M++EIFGP+L I V+ ++EA++FIN R KPL LY
Sbjct: 306 GGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALY 365
Query: 408 VFSSSEKVHKIFASHTSSGSICFND 432
FS+S +V K + TSSG C ND
Sbjct: 366 AFSNSSQVVKRVLTQTSSGGFCGND 390
>BT009832-1|AAP88834.1| 468|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 468
Score = 395 bits (973), Expect = e-109
Identities = 180/385 (46%), Positives = 264/385 (68%), Gaps = 2/385 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL +S ES + E+
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
+ ++ L NL +W K ER ++ LD FI +P+G+VLII WNYPL L+L+P+ G
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVG 127
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
A+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET +LL HRFDYIF+T
Sbjct: 128 ALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFT 187
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
GS +GKI+ +AAKHLTPVTLELGGK+P Y+DD D + +R+ W ++ NAGQTC+AP
Sbjct: 188 GSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAP 247
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DYVLC+ E+QE+ + + + +++GDDPQ +P+ RI+N + F RL+A+L R +AI
Sbjct: 248 DYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR--VAI 305
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D D++I T+L +V + +M++EIFGP+L I V+ ++EA++FIN R KPL LY
Sbjct: 306 GGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALY 365
Query: 408 VFSSSEKVHKIFASHTSSGSICFND 432
FS+S +V K + TSSG C ND
Sbjct: 366 AFSNSSQVVKRVLTQTSSGGFCGND 390
>BC013584-1|AAH13584.1| 468|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 468
Score = 395 bits (973), Expect = e-109
Identities = 180/385 (46%), Positives = 264/385 (68%), Gaps = 2/385 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL +S ES + E+
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
+ ++ L NL +W K ER ++ LD FI +P+G+VLII WNYPL L+L+P+ G
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVG 127
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
A+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET +LL HRFDYIF+T
Sbjct: 128 ALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFT 187
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
GS +GKI+ +AAKHLTPVTLELGGK+P Y+DD D + +R+ W ++ NAGQTC+AP
Sbjct: 188 GSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAP 247
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DYVLC+ E+QE+ + + + +++GDDPQ +P+ RI+N + F RL+A+L R +AI
Sbjct: 248 DYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR--VAI 305
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D D++I T+L +V + +M++EIFGP+L I V+ ++EA++FIN R KPL LY
Sbjct: 306 GGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALY 365
Query: 408 VFSSSEKVHKIFASHTSSGSICFND 432
FS+S +V K + TSSG C ND
Sbjct: 366 AFSNSSQVVKRVLTQTSSGGFCGND 390
>U75296-1|AAC50966.1| 485|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 485
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>U75295-1|AAC50965.1| 508|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 508
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>U46689-1|AAC51121.1| 485|Homo sapiens aldehyde dehydrogenase
protein.
Length = 485
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>L47162-1|AAB01003.1| 485|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 485
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>CR457422-1|CAG33703.1| 485|Homo sapiens ALDH3A2 protein.
Length = 485
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>BC002430-1|AAH02430.1| 508|Homo sapiens aldehyde dehydrogenase 3
family, member A2 protein.
Length = 508
Score = 392 bits (964), Expect = e-108
Identities = 184/388 (47%), Positives = 266/388 (68%), Gaps = 2/388 (0%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
V++VR+ + SG +R L++R +QL L RM +E +L + DL +S+ E+ +
Sbjct: 5 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITV 64
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
++ +L NL W + ++ + LD+ +I P GVVLIIGAWNYP L++ P+ G
Sbjct: 65 LGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIG 124
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
AIAAGN VI+KPSE+S +A+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYT
Sbjct: 125 AIAAGNAVIIKPSELSENTAKILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYT 184
Query: 228 GSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAP 287
G+T +GKI+ +AAKHLTPVTLELGGKSP YID DL++ RI WGK++N GQTCIAP
Sbjct: 185 GNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAP 244
Query: 288 DYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAI 347
DY+LC +Q + + K K +K+++G++ +++PDY RI+N RHF R+ ++L+ KIA
Sbjct: 245 DYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAF 302
Query: 348 GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLY 407
GG+ D ++I T+LT+VD K+M++EIFGP+L I VK+++EA+ FINER KPL LY
Sbjct: 303 GGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALY 362
Query: 408 VFSSSEKVHKIFASHTSSGSICFNDTIV 435
VFS + K+ K TSSG + ND I+
Sbjct: 363 VFSHNHKLIKRMIDETSSGGVTGNDVIM 390
>M74542-1|AAA51696.1| 453|Homo sapiens aldehyde dehydrogenase type
III protein.
Length = 453
Score = 391 bits (962), Expect = e-108
Identities = 180/390 (46%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ R ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRARAAFSSGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>BT007102-1|AAP35766.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 391 bits (962), Expect = e-108
Identities = 180/390 (46%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ R ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>BC021194-1|AAH21194.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 391 bits (962), Expect = e-108
Identities = 180/390 (46%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ R ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>BC008892-1|AAH08892.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 391 bits (962), Expect = e-108
Identities = 180/390 (46%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ R ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>BC004370-1|AAH04370.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 391 bits (962), Expect = e-108
Identities = 180/390 (46%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ R ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>S61044-1|AAB26658.1| 453|Homo sapiens aldehyde dehydrogenase
isozyme 3 protein.
Length = 453
Score = 388 bits (956), Expect = e-107
Identities = 179/390 (45%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRAPAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN+V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>M77477-1|AAB46377.1| 453|Homo sapiens aldehyde dehydrogenase
protein.
Length = 453
Score = 388 bits (956), Expect = e-107
Identities = 179/390 (45%), Positives = 265/390 (67%), Gaps = 2/390 (0%)
Query: 46 QAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEID 105
+AV++ ++SG TR L++R +QL L R+ +E ++ L DL +++ + E+
Sbjct: 6 EAVKRAPAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVV 65
Query: 106 YMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPM 165
Y+ ++++++ L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM
Sbjct: 66 YVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPM 125
Query: 166 AGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIF 225
GAIAAGN+V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I
Sbjct: 126 VGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHIL 185
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCI 285
YTGST +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+
Sbjct: 186 YTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCV 245
Query: 286 APDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKI 345
APDY+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+
Sbjct: 246 APDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKV 303
Query: 346 AIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLV 405
A GG D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL
Sbjct: 304 AYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLA 363
Query: 406 LYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
LY+FSS++KV K + TSSG + ND IV
Sbjct: 364 LYMFSSNDKVIKKMIAETSSGGVAANDVIV 393
>BC004102-1|AAH04102.1| 512|Homo sapiens ALDH3A1 protein protein.
Length = 512
Score = 381 bits (937), Expect = e-105
Identities = 176/378 (46%), Positives = 256/378 (67%), Gaps = 2/378 (0%)
Query: 58 GVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYN 117
G TR L++R +QL L R+ +E ++ L DL +++ + E+ Y+ ++++++
Sbjct: 77 GRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQK 136
Query: 118 LDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIV 177
L W E ++ D+++I+ +P GVVL+IG WNYP L++ PM GAIAAGN V++
Sbjct: 137 LPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVL 196
Query: 178 KPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIY 237
KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I YTGST +GKII
Sbjct: 197 KPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIM 256
Query: 238 ASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQ 297
+AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+APDY+LC IQ
Sbjct: 257 TAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQ 316
Query: 298 EKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKF 357
+ ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+A GG D ++
Sbjct: 317 NQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKVAYGGTGDAATRY 374
Query: 358 IDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHK 417
I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL LY+FSS++KV K
Sbjct: 375 IAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIK 434
Query: 418 IFASHTSSGSICFNDTIV 435
+ TSSG + ND IV
Sbjct: 435 KMIAETSSGGVAANDVIV 452
>AB208894-1|BAD92131.1| 461|Homo sapiens aldehyde dehydrogenase 3A2
variant protein.
Length = 461
Score = 376 bits (926), Expect = e-104
Identities = 176/368 (47%), Positives = 251/368 (68%), Gaps = 2/368 (0%)
Query: 68 KQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPERP 127
+QL L RM +E +L + DL +S+ E+ + ++ +L NL W +
Sbjct: 1 QQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTAKPV 60
Query: 128 DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASA 187
++ + LD+ +I P GVVLIIGAWNYP L++ P+ GAIAAGN VI+KPSE+S +A
Sbjct: 61 KKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTA 120
Query: 188 RFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPV 247
+ + + +P+YLD D I+I GG +ETT+LL RFD+IFYTG+T +GKI+ +AAKHLTPV
Sbjct: 121 KILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYTGNTAVGKIVMEAAAKHLTPV 180
Query: 248 TLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRI 307
TLELGGKSP YID DL++ RI WGK++N GQTCIAPDY+LC +Q + + K K
Sbjct: 181 TLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKET 240
Query: 308 LKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVD 367
+K+++G++ +++PDY RI+N RHF R+ ++L+ KIA GG+ D ++I T+LT+VD
Sbjct: 241 VKEFYGENIKESPDYERIINLRHFKRILSLLEG--QKIAFGGETDEATRYIAPTVLTDVD 298
Query: 368 VNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGS 427
K+M++EIFGP+L I VK+++EA+ FINER KPL LYVFS + K+ K TSSG
Sbjct: 299 PKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGG 358
Query: 428 ICFNDTIV 435
+ ND I+
Sbjct: 359 VTGNDVIM 366
>AB209651-1|BAD92888.1| 447|Homo sapiens aldehyde dehydrogenase 3B1
variant protein.
Length = 447
Score = 360 bits (885), Expect = 6e-99
Identities = 162/339 (47%), Positives = 234/339 (69%), Gaps = 2/339 (0%)
Query: 94 RSKTESLLLEIDYMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGA 153
+S ES + E+ + ++ L NL +W K ER ++ LD FI +P+G+VLII
Sbjct: 33 QSAFESEVSEVAISQGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAP 92
Query: 154 WNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQET 213
WNYPL L+L+P+ GA+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET
Sbjct: 93 WNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQET 152
Query: 214 TKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRIL 273
+LL HRFDYIF+TGS +GKI+ +AAKHLTPVTLELGGK+P Y+DD D + +R+
Sbjct: 153 GQLLEHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVA 212
Query: 274 WGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSR 333
W ++ NAGQTC+APDYVLC+ E+QE+ + + + +++GDDPQ +P+ RI+N + F R
Sbjct: 213 WFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQR 272
Query: 334 LQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEA 393
L+A+L R +AIGG+ D D++I T+L +V + +M++EIFGP+L I V+ ++EA
Sbjct: 273 LRALLGCGR--VAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEA 330
Query: 394 LKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFND 432
++FIN R KPL LY FS+S +V K + TSSG C ND
Sbjct: 331 IEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGND 369
>BC033099-1|AAH33099.1| 431|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 431
Score = 342 bits (841), Expect = 1e-93
Identities = 151/298 (50%), Positives = 214/298 (71%), Gaps = 2/298 (0%)
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
LD FI +P+G+VLII WNYPL L+L+P+ GA+AAGN V++KPSEIS + + E +
Sbjct: 58 LDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVL 117
Query: 195 PKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGK 254
P+Y+D ++ GGPQET +LL HRFDYIF+TGS +GKI+ +AAKHLTPVTLELGGK
Sbjct: 118 PQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGK 177
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGD 314
+P Y+DD D + +R+ W ++ NAGQTC+APDYVLC+ E+QE+ + + + +++GD
Sbjct: 178 NPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 237
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIME 374
DPQ +P+ RI+N + F RL+A+L R +AIGG+ D D++I T+L +V + +M+
Sbjct: 238 DPQSSPNLGRIINQKQFQRLRALLGCGR--VAIGGQSDESDRYIAPTVLVDVQEMEPVMQ 295
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFND 432
+EIFGP+L I V+ ++EA++FIN R KPL LY FS+S +V K + TSSG C ND
Sbjct: 296 EEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGND 353
Score = 40.3 bits (90), Expect = 0.013
Identities = 18/48 (37%), Positives = 32/48 (66%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRS 95
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL ++
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKA 55
>BT006810-1|AAP35456.1| 385|Homo sapiens aldehyde dehydrogenase 3
family, member B2 protein.
Length = 385
Score = 326 bits (802), Expect = 7e-89
Identities = 145/302 (48%), Positives = 212/302 (70%), Gaps = 2/302 (0%)
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
LD VFI+ +P+G+VLII WNYPL L+L+ + GA+AAG+ V++KPSEIS + + + E +
Sbjct: 14 LDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVL 73
Query: 195 PKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGK 254
P+YLD ++ GGPQET +LL H+ DYIF+TGS +GKI+ +A KHLTPVTLELGGK
Sbjct: 74 PQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGK 133
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGD 314
+P Y+DD D + +R+ W + NAGQTC+APDYVLC+ E+QE+ + + + +++GD
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 193
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIME 374
DPQ +P+ RI+N + F RL+A+L R +AIGG+ + D++I T+L +V + +M+
Sbjct: 194 DPQSSPNLGRIINQKQFQRLRALLGCGR--VAIGGQSNESDRYIAPTVLVDVQETEPVMQ 251
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTI 434
+EIFGP+L I V+ ++EA+KFIN + KPL LY FS+S +V TSSGS N+
Sbjct: 252 EEIFGPILPIVNVQSVDEAIKFINWQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGF 311
Query: 435 VF 436
+
Sbjct: 312 TY 313
>BC007685-1|AAH07685.1| 385|Homo sapiens aldehyde dehydrogenase 3
family, member B2 protein.
Length = 385
Score = 326 bits (802), Expect = 7e-89
Identities = 145/302 (48%), Positives = 212/302 (70%), Gaps = 2/302 (0%)
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
LD VFI+ +P+G+VLII WNYPL L+L+ + GA+AAG+ V++KPSEIS + + + E +
Sbjct: 14 LDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVL 73
Query: 195 PKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGK 254
P+YLD ++ GGPQET +LL H+ DYIF+TGS +GKI+ +A KHLTPVTLELGGK
Sbjct: 74 PQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGK 133
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGD 314
+P Y+DD D + +R+ W + NAGQTC+APDYVLC+ E+QE+ + + + +++GD
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 193
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIME 374
DPQ +P+ RI+N + F RL+A+L R +AIGG+ + D++I T+L +V + +M+
Sbjct: 194 DPQSSPNLGRIINQKQFQRLRALLGCGR--VAIGGQSNESDRYIAPTVLVDVQETEPVMQ 251
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTI 434
+EIFGP+L I V+ ++EA+KFIN + KPL LY FS+S +V TSSGS N+
Sbjct: 252 EEIFGPILPIVNVQSVDEAIKFINWQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGF 311
Query: 435 VF 436
+
Sbjct: 312 TY 313
>U37519-1|AAA85441.1| 385|Homo sapiens aldehyde dehydrogenase
protein.
Length = 385
Score = 326 bits (801), Expect = 9e-89
Identities = 144/302 (47%), Positives = 210/302 (69%), Gaps = 2/302 (0%)
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
LD VFI+ +P+G+VLII WNYPL L+L+ + G + AGN V++KPSEIS + + + E +
Sbjct: 14 LDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVL 73
Query: 195 PKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGK 254
P+YLD ++ GGPQET +LL H+ DYIF+TGS +GKI+ +A KHLTPVTLELGGK
Sbjct: 74 PQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGK 133
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGD 314
+P Y+DD D + +R+ W + NAGQTC+APDYVLC+ E+QE+ + + + +++GD
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 193
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIME 374
DPQ +P+ RI+N + F RL+A+L R +AIGG+ + D++I T+L +V + +M+
Sbjct: 194 DPQSSPNLGRIINQKQFQRLRALLGCGR--VAIGGQSNESDRYIAPTVLVDVQETEPVMQ 251
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTI 434
+EIFGP+L I V+ ++EA+KFIN + KPL LY FS+S +V TSSGS N+
Sbjct: 252 EEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSSGSFGGNEGF 311
Query: 435 VF 436
+
Sbjct: 312 TY 313
>AK092464-1|BAC03897.1| 385|Homo sapiens protein ( Homo sapiens
cDNA FLJ35145 fis, clone PLACE6009853, highly similar to
ALDEHYDE DEHYDROGENASE 8 (EC 1.2.1.5). ).
Length = 385
Score = 326 bits (801), Expect = 9e-89
Identities = 145/302 (48%), Positives = 211/302 (69%), Gaps = 2/302 (0%)
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
LD VFI+ +P+G+VLII WNYPL L+L+ + GA+AAGN V++KPSEIS + + + E +
Sbjct: 14 LDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGNCVVLKPSEISQGTEKVLAEVL 73
Query: 195 PKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGK 254
P+YLD ++ GGPQET +LL H+ DYIF+TGS +GKI+ +A KHLTPVTLELG K
Sbjct: 74 PQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGVK 133
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGD 314
+P Y+DD D + +R+ W + NAGQTC+APDYVLC+ E+QE+ + + + +++GD
Sbjct: 134 NPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGD 193
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGGKYDPGDKFIDLTILTNVDVNDKIME 374
DPQ +P+ RI+N + F RL+A+L R +AIGG+ + D++I T+L +V + +M+
Sbjct: 194 DPQSSPNLGRIINQKQFQRLRALLGCGR--VAIGGQSNESDRYIAPTVLVDVQETEPVMQ 251
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTI 434
+EIFGP+L I V+ ++EA+KFIN + KPL LY FS+S +V TSSGS N+
Sbjct: 252 EEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGF 311
Query: 435 VF 436
+
Sbjct: 312 TY 313
>AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ36558 fis, clone TRACH2009107, highly similar to
ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC
1.2.1.5). ).
Length = 570
Score = 303 bits (743), Expect = 1e-81
Identities = 138/266 (51%), Positives = 190/266 (71%), Gaps = 2/266 (0%)
Query: 170 AAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYTGS 229
+AGN V++KPSE+S A + IP+YLD D +I GG ETT+LL RFD+I YTGS
Sbjct: 247 SAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGS 306
Query: 230 TNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDY 289
T +GKII +AAKHLTPVTLELGGKSP Y+D DL++ RI WGKF+N+GQTC+APDY
Sbjct: 307 TGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDY 366
Query: 290 VLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHKIAIGG 349
+LC IQ + ++K K+ LK+++G+D +K+ DY RI++ RHF R+ +++ K+A GG
Sbjct: 367 ILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG--QKVAYGG 424
Query: 350 KYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVF 409
D ++I TILT+VD +M++EIFGP+L I V+ + EA++FIN+R KPL LY+F
Sbjct: 425 TGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMF 484
Query: 410 SSSEKVHKIFASHTSSGSICFNDTIV 435
SS++KV K + TSSG + ND IV
Sbjct: 485 SSNDKVIKKMIAETSSGGVAANDVIV 510
>BC002553-1|AAH02553.1| 230|Homo sapiens ALDH3B1 protein protein.
Length = 230
Score = 194 bits (472), Expect = 7e-49
Identities = 89/196 (45%), Positives = 131/196 (66%)
Query: 48 VQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYM 107
++++RE +++G TR ++R QL+ L R +EN L+ D L QDL +S ES + E+
Sbjct: 8 LRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAIS 67
Query: 108 KNDLKHVLYNLDSWTKPERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAG 167
+ ++ L NL +W K ER ++ LD FI +P+G+VLII WNYPL L+L+P+ G
Sbjct: 68 QGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVG 127
Query: 168 AIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRFDYIFYT 227
A+AAGN V++KPSEIS + + E +P+Y+D ++ GGPQET +LL HRFDYIF+T
Sbjct: 128 ALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFT 187
Query: 228 GSTNIGKIIYASAAKH 243
GS +GKI+ +AAKH
Sbjct: 188 GSPRVGKIVMTAAAKH 203
>U07919-1|AAA79036.1| 512|Homo sapiens aldehyde dehydrogenase 6
protein.
Length = 512
Score = 145 bits (352), Expect = 2e-34
Identities = 95/303 (31%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + + +A A+ GNT+++KP+E +P +A ++ I +
Sbjct: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
V+ I+ G GP + SH + + I +TGST +GK++ +A++ +L VTLELGGK
Sbjct: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FG 313
+P + ADL++ V+ G F N GQ C A V +++ +F+++S KK G
Sbjct: 285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVG 344
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDKFIDLTILTNVDVN 369
D + ++ + F ++ ++++ + K+ GG + FI T+ + V N
Sbjct: 345 DPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDN 404
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSI 428
+I ++EIFGP+ I K I E +K N L VF+ + +K K+ AS SG++
Sbjct: 405 MRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKL-ASALESGTV 463
Query: 429 CFN 431
N
Sbjct: 464 WIN 466
>DQ322171-1|ABC40749.1| 518|Homo sapiens aldehyde dehydrogenase 1
family, member A2 protein.
Length = 518
Score = 145 bits (352), Expect = 2e-34
Identities = 100/303 (33%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + +A A+ GNTV++KP+E +P SA ++ I +
Sbjct: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 230
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
VI I+ G GP + SH D I +TGST +GK+I +A + +L VTLELGGK
Sbjct: 231 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 290
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFG 313
SP I ADL+ V++ G F N GQ C A + + I E+F+++S +R ++ G
Sbjct: 291 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG 350
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLD---ASRHKIAIGGKYDPGDK--FIDLTILTNVDV 368
T + ++ + ++++ ++ A K+ GGK G K FI+ T+ +NV
Sbjct: 351 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-GLGRKGFFIEPTVFSNVTD 409
Query: 369 NDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSI 428
+ +I ++EIFGP+ I K ++E ++ N LV VF++ +S +G++
Sbjct: 410 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 469
Query: 429 CFN 431
N
Sbjct: 470 WIN 472
>BC069274-1|AAH69274.1| 512|Homo sapiens aldehyde dehydrogenase 1
family, member A3 protein.
Length = 512
Score = 145 bits (352), Expect = 2e-34
Identities = 95/303 (31%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + + +A A+ GNT+++KP+E +P +A ++ I +
Sbjct: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
V+ I+ G GP + SH + + I +TGST +GK++ +A++ +L VTLELGGK
Sbjct: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FG 313
+P + ADL++ V+ G F N GQ C A V +++ +F+++S KK G
Sbjct: 285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVG 344
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDKFIDLTILTNVDVN 369
D + ++ + F ++ ++++ + K+ GG + FI T+ + V N
Sbjct: 345 DPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDN 404
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSI 428
+I ++EIFGP+ I K I E +K N L VF+ + +K K+ AS SG++
Sbjct: 405 MRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKL-ASALESGTV 463
Query: 429 CFN 431
N
Sbjct: 464 WIN 466
>AB015228-1|BAA34787.1| 422|Homo sapiens RALDH2-T protein.
Length = 422
Score = 145 bits (352), Expect = 2e-34
Identities = 100/303 (33%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + +A A+ GNTV++KP+E +P SA ++ I +
Sbjct: 75 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 134
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
VI I+ G GP + SH D I +TGST +GK+I +A + +L VTLELGGK
Sbjct: 135 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 194
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFG 313
SP I ADL+ V++ G F N GQ C A + + I E+F+++S +R ++ G
Sbjct: 195 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRIVG 254
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLD---ASRHKIAIGGKYDPGDK--FIDLTILTNVDV 368
T + ++ + ++++ ++ A K+ GGK G K FI+ T+ +NV
Sbjct: 255 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-GLGRKGFFIEPTVFSNVTD 313
Query: 369 NDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSI 428
+ +I ++EIFGP+ I K ++E ++ N LV VF++ +S +G++
Sbjct: 314 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 373
Query: 429 CFN 431
N
Sbjct: 374 WIN 376
>AB015227-1|BAA34786.1| 422|Homo sapiens RALDH2-T protein.
Length = 422
Score = 145 bits (352), Expect = 2e-34
Identities = 100/303 (33%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + +A A+ GNTV++KP+E +P SA ++ I +
Sbjct: 75 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 134
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
VI I+ G GP + SH D I +TGST +GK+I +A + +L VTLELGGK
Sbjct: 135 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 194
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFG 313
SP I ADL+ V++ G F N GQ C A + + I E+F+++S +R ++ G
Sbjct: 195 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRIVG 254
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLD---ASRHKIAIGGKYDPGDK--FIDLTILTNVDV 368
T + ++ + ++++ ++ A K+ GGK G K FI+ T+ +NV
Sbjct: 255 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-GLGRKGFFIEPTVFSNVTD 313
Query: 369 NDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSI 428
+ +I ++EIFGP+ I K ++E ++ N LV VF++ +S +G++
Sbjct: 314 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 373
Query: 429 CFN 431
N
Sbjct: 374 WIN 376
>AB015226-1|BAA34785.1| 518|Homo sapiens RALDH2 protein.
Length = 518
Score = 145 bits (352), Expect = 2e-34
Identities = 100/303 (33%), Positives = 161/303 (53%), Gaps = 11/303 (3%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F H+P GV I WN+PL + +A A+ GNTV++KP+E +P SA ++ I +
Sbjct: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAG 230
Query: 199 DNDAVI-IIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGK 254
VI I+ G GP + SH D I +TGST +GK+I +A + +L VTLELGGK
Sbjct: 231 FPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGK 290
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFG 313
SP I ADL+ V++ G F N GQ C A + + I E+F+++S +R ++ G
Sbjct: 291 SPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRIVG 350
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLD---ASRHKIAIGGKYDPGDK--FIDLTILTNVDV 368
T + ++ + ++++ ++ A K+ GGK G K FI+ T+ +NV
Sbjct: 351 SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGK-GLGRKGFFIEPTVFSNVTD 409
Query: 369 NDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSI 428
+ +I ++EIFGP+ I K ++E ++ N LV VF++ +S +G++
Sbjct: 410 DMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTV 469
Query: 429 CFN 431
N
Sbjct: 470 WIN 472
>M31994-1|AAA51692.1| 501|Homo sapiens aldehyde dehydrogenase
protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>BT006921-1|AAP35567.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>BC001505-1|AAH01505.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>AY390731-1|AAR92229.1| 501|Homo sapiens aldehyde dehydrogenase 1
A1 protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>AY338497-1|AAP88039.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>AL591031-1|CAI12257.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 137 bits (332), Expect = 6e-32
Identities = 117/419 (27%), Positives = 200/419 (47%), Gaps = 22/419 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 203 VI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 218 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 277
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQK 318
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 278 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-L 336
Query: 319 TPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKI 372
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +I
Sbjct: 337 TPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRI 396
Query: 373 MEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 397 AKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>AF003341-1|AAC51652.1| 501|Homo sapiens aldehyde dehydrogenase 1
protein.
Length = 501
Score = 136 bits (330), Expect = 1e-31
Identities = 91/300 (30%), Positives = 156/300 (52%), Gaps = 11/300 (3%)
Query: 142 HDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDND 201
H+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 157 HEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPP 216
Query: 202 AVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPV 257
V+ I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 217 GVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPC 276
Query: 258 YIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQ 317
+ ADL+ V+ G F + GQ CIA + + I ++F+++S KK+ +P
Sbjct: 277 IVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP- 335
Query: 318 KTPDYSR--IVNNRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDK 371
TP ++ ++ + ++ ++++ + + A GG + F+ T+ +NV +
Sbjct: 336 LTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMR 395
Query: 372 IMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
I ++EIFGP+ I K +++ +K N L VF+ +S +G++ N
Sbjct: 396 IAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 455
>M26761-1|AAA35518.1| 340|Homo sapiens aldehyde dehydrogenase I
protein.
Length = 340
Score = 130 bits (313), Expect = 1e-29
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 11/288 (3%)
Query: 154 WNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQ 211
WN+PL + + + A++ GNTV+VKP+E +P +A + I + V+ I+ G GP
Sbjct: 8 WNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPT 67
Query: 212 ETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVYIDDTADLEMTV 269
+ SH D + +TGST +GK+I +A K +L VTLELGGKSP + ADL+ V
Sbjct: 68 AGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAV 127
Query: 270 DRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSR--IVN 327
+ G F + GQ CIA + + I ++F+++S KK+ +P TP ++ ++
Sbjct: 128 EFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-LTPGVTQGPQID 186
Query: 328 NRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLA 383
+ ++ ++++ + + A GG + F+ T+ +NV +I ++EIFGP+
Sbjct: 187 KEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQ 246
Query: 384 ICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
I K +++ +K N L VF+ +S +G++ N
Sbjct: 247 IMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 294
>K03000-1|AAA51695.1| 340|Homo sapiens ALDH1 protein.
Length = 340
Score = 130 bits (313), Expect = 1e-29
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 11/288 (3%)
Query: 154 WNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQ 211
WN+PL + + + A++ GNTV+VKP+E +P +A + I + V+ I+ G GP
Sbjct: 8 WNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPT 67
Query: 212 ETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVYIDDTADLEMTV 269
+ SH D + +TGST +GK+I +A K +L VTLELGGKSP + ADL+ V
Sbjct: 68 AGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAV 127
Query: 270 DRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSR--IVN 327
+ G F + GQ CIA + + I ++F+++S KK+ +P TP ++ ++
Sbjct: 128 EFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNP-LTPGVTQGPQID 186
Query: 328 NRHFSRLQAVLDASRHKIAI----GGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLA 383
+ ++ ++++ + + A GG + F+ T+ +NV +I ++EIFGP+
Sbjct: 187 KEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQ 246
Query: 384 ICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFN 431
I K +++ +K N L VF+ +S +G++ N
Sbjct: 247 IMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVN 294
>AY621070-1|AAT41621.1| 517|Homo sapiens mitochondrial aldehyde
dehydrogenase 2 protein.
Length = 517
Score = 129 bits (311), Expect = 2e-29
Identities = 118/432 (27%), Positives = 197/432 (45%), Gaps = 29/432 (6%)
Query: 23 TRNFTEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENAN 82
T N + E+ V E + ++ +AV+ R + G WRR + R+ A+
Sbjct: 56 TVNPSTGEVICQVAE-GDKEDVDKAVKAARAAFQLGSP----WRRMDASHRGRLLNRLAD 110
Query: 83 LM-LDVLY----QDLRRSKTE--SLLLEIDYMKNDLKHVLYNLDSWTKPERP-DRDFVNW 134
L+ D Y + L K S L+++D + L++ D + P D DF +
Sbjct: 111 LIERDQTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFS- 169
Query: 135 LDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
+ H+P GV I WN+PL + + A+A GN V++K +E +P +A ++ I
Sbjct: 170 ----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLI 225
Query: 195 PKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLE 250
+ V+ I+ G GP + SH D + +TGST IG++I +A + +L VTLE
Sbjct: 226 KEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLE 285
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILK 309
LGGKSP I AD++ V++ + F N GQ C A ++I ++F+++S R
Sbjct: 286 LGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKS 345
Query: 310 KWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILT 364
+ G+ + V+ F ++ ++ + K+ GG D G FI T+
Sbjct: 346 RVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFG 404
Query: 365 NVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTS 424
+V I ++EIFGP++ I K I E + N L VF+ +
Sbjct: 405 DVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQ 464
Query: 425 SGSICFNDTIVF 436
+G++ N VF
Sbjct: 465 AGTVWVNCYDVF 476
>M20456-1|AAA51693.1| 517|Homo sapiens aldehyde dehydrogenase
protein.
Length = 517
Score = 128 bits (310), Expect = 3e-29
Identities = 104/382 (27%), Positives = 176/382 (46%), Gaps = 17/382 (4%)
Query: 66 RRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPE 125
R + L L + E + + + D + S L+++D + L++ D +
Sbjct: 101 RGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT 160
Query: 126 RP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISP 184
P D DF + + H+P GV I WN+PL + + A+A GN V++K +E +P
Sbjct: 161 IPIDGDFFS-----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTP 215
Query: 185 ASARFIVEYIPKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA- 240
+A ++ I + V+ I+ G GP + SH D + +TGST IG++I +A
Sbjct: 216 LTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAG 275
Query: 241 AKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKF 300
+ +L VTLELGGKSP I AD++ V++ + F N GQ C A ++I ++F
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 301 IQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPG 354
+++S R + G+ + V+ F ++ ++ + K+ GG D G
Sbjct: 336 VERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQQGAKLLCGGGIAADRG 395
Query: 355 DKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEK 414
FI T+ +V I ++EIFGP++ I K I E + N L VF+
Sbjct: 396 -YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLD 454
Query: 415 VHKIFASHTSSGSICFNDTIVF 436
+ +G++ N VF
Sbjct: 455 KANYLSQALQAGTVWVNCYDVF 476
>BC071839-1|AAH71839.1| 517|Homo sapiens aldehyde dehydrogenase 2
family (mitochondrial) protein.
Length = 517
Score = 128 bits (310), Expect = 3e-29
Identities = 104/382 (27%), Positives = 176/382 (46%), Gaps = 17/382 (4%)
Query: 66 RRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPE 125
R + L L + E + + + D + S L+++D + L++ D +
Sbjct: 101 RGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT 160
Query: 126 RP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISP 184
P D DF + + H+P GV I WN+PL + + A+A GN V++K +E +P
Sbjct: 161 IPIDGDFFS-----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTP 215
Query: 185 ASARFIVEYIPKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA- 240
+A ++ I + V+ I+ G GP + SH D + +TGST IG++I +A
Sbjct: 216 LTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAG 275
Query: 241 AKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKF 300
+ +L VTLELGGKSP I AD++ V++ + F N GQ C A ++I ++F
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 301 IQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPG 354
+++S R + G+ + V+ F ++ ++ + K+ GG D G
Sbjct: 336 VERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG 395
Query: 355 DKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEK 414
FI T+ +V I ++EIFGP++ I K I E + N L VF+
Sbjct: 396 -YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLD 454
Query: 415 VHKIFASHTSSGSICFNDTIVF 436
+ +G++ N VF
Sbjct: 455 KANYLSQALQAGTVWVNCYDVF 476
>BC002967-1|AAH02967.1| 517|Homo sapiens aldehyde dehydrogenase 2
family (mitochondrial) protein.
Length = 517
Score = 128 bits (310), Expect = 3e-29
Identities = 104/382 (27%), Positives = 176/382 (46%), Gaps = 17/382 (4%)
Query: 66 RRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPE 125
R + L L + E + + + D + S L+++D + L++ D +
Sbjct: 101 RGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT 160
Query: 126 RP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISP 184
P D DF + + H+P GV I WN+PL + + A+A GN V++K +E +P
Sbjct: 161 IPIDGDFFS-----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTP 215
Query: 185 ASARFIVEYIPKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA- 240
+A ++ I + V+ I+ G GP + SH D + +TGST IG++I +A
Sbjct: 216 LTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAG 275
Query: 241 AKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKF 300
+ +L VTLELGGKSP I AD++ V++ + F N GQ C A ++I ++F
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 301 IQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPG 354
+++S R + G+ + V+ F ++ ++ + K+ GG D G
Sbjct: 336 VERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG 395
Query: 355 DKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEK 414
FI T+ +V I ++EIFGP++ I K I E + N L VF+
Sbjct: 396 -YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLD 454
Query: 415 VHKIFASHTSSGSICFNDTIVF 436
+ +G++ N VF
Sbjct: 455 KANYLSQALQAGTVWVNCYDVF 476
>AK223373-1|BAD97093.1| 517|Homo sapiens mitochondrial aldehyde
dehydrogenase 2 precursor variant protein.
Length = 517
Score = 128 bits (310), Expect = 3e-29
Identities = 104/382 (27%), Positives = 176/382 (46%), Gaps = 17/382 (4%)
Query: 66 RRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPE 125
R + L L + E + + + D + S L+++D + L++ D +
Sbjct: 101 RGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT 160
Query: 126 RP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISP 184
P D DF + + H+P GV I WN+PL + + A+A GN V++K +E +P
Sbjct: 161 IPIDGDFFS-----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTP 215
Query: 185 ASARFIVEYIPKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA- 240
+A ++ I + V+ I+ G GP + SH D + +TGST IG++I +A
Sbjct: 216 LTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAG 275
Query: 241 AKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKF 300
+ +L VTLELGGKSP I AD++ V++ + F N GQ C A ++I ++F
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 301 IQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPG 354
+++S R + G+ + V+ F ++ ++ + K+ GG D G
Sbjct: 336 VERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG 395
Query: 355 DKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEK 414
FI T+ +V I ++EIFGP++ I K I E + N L VF+
Sbjct: 396 -YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLD 454
Query: 415 VHKIFASHTSSGSICFNDTIVF 436
+ +G++ N VF
Sbjct: 455 KANYLSQALQAGTVWVNCYDVF 476
>Y00109-1|CAA68290.1| 515|Homo sapiens protein ( Human mRNA for
mitochondrial aldehyde dehydrogenase (ALDH I). ).
Length = 515
Score = 127 bits (307), Expect = 7e-29
Identities = 113/410 (27%), Positives = 185/410 (45%), Gaps = 24/410 (5%)
Query: 45 RQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-LDVLY----QDLRRSKTE- 98
++ V K RE WRR + R+ A+L+ D Y + L K
Sbjct: 71 KEDVDKAREGRPGAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYV 130
Query: 99 -SLLLEIDYMKNDLKHVLYNLDSWTKPERP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNY 156
S L+++D + L++ D + P D DF + + H+P GV I WN+
Sbjct: 131 ISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFS-----YTRHEPVGVCGQIIPWNF 185
Query: 157 PLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQETT 214
PL + + A+A GN V++K +E +P +A ++ I + V+ I+ G GP
Sbjct: 186 PLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGA 245
Query: 215 KLLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLELGGKSPVYIDDTADLEMTVDRI 272
+ SH D + +TGST IG++I +A + +L VTLELGGKSP I AD++ V++
Sbjct: 246 AIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQA 305
Query: 273 LWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGDDPQKTPDYSRIVNNRHF 331
+ F N GQ C A ++I ++F+ +S R + G+ + V+ F
Sbjct: 306 HFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQF 365
Query: 332 SRLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICV 386
++ ++ + K+ GG D G FI T+ +V I ++EIFGP++ I
Sbjct: 366 KKILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILK 424
Query: 387 VKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTIVF 436
K I E + N L VF+ + +G++ N VF
Sbjct: 425 FKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF 474
>X05409-1|CAA28990.1| 516|Homo sapiens protein ( Human RNA for
mitochondrial aldehyde dehydrogenase I ALDH I (EC
1.2.1.3). ).
Length = 516
Score = 127 bits (307), Expect = 7e-29
Identities = 113/410 (27%), Positives = 185/410 (45%), Gaps = 24/410 (5%)
Query: 45 RQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-LDVLY----QDLRRSKTE- 98
++ V K RE WRR + R+ A+L+ D Y + L K
Sbjct: 72 KEDVDKAREGRPGAFQLGSPWRRMDASHSGRLLNRLADLIERDRTYLAALETLDNGKPYV 131
Query: 99 -SLLLEIDYMKNDLKHVLYNLDSWTKPERP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNY 156
S L+++D + L++ D + P D DF + + H+P GV I WN+
Sbjct: 132 ISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFS-----YTRHEPVGVCGQIIPWNF 186
Query: 157 PLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQETT 214
PL + + A+A GN V++K +E +P +A ++ I + V+ I+ G GP
Sbjct: 187 PLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGA 246
Query: 215 KLLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLELGGKSPVYIDDTADLEMTVDRI 272
+ SH D + +TGST IG++I +A + +L VTLELGGKSP I AD++ V++
Sbjct: 247 AIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQA 306
Query: 273 LWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGDDPQKTPDYSRIVNNRHF 331
+ F N GQ C A ++I ++F+ +S R + G+ + V+ F
Sbjct: 307 HFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQF 366
Query: 332 SRLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICV 386
++ ++ + K+ GG D G FI T+ +V I ++EIFGP++ I
Sbjct: 367 KKILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILK 425
Query: 387 VKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTIVF 436
K I E + N L VF+ + +G++ N VF
Sbjct: 426 FKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF 475
>CR456991-1|CAG33272.1| 517|Homo sapiens ALDH2 protein.
Length = 517
Score = 127 bits (307), Expect = 7e-29
Identities = 103/382 (26%), Positives = 176/382 (46%), Gaps = 17/382 (4%)
Query: 66 RRKQLRNLYRMYEENANLMLDVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPE 125
R + L L + E + + + D + S L+++D + L++ D +
Sbjct: 101 RGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKT 160
Query: 126 RP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISP 184
P D DF + + H+P GV I WN+PL + + A+A GN V++K +E +P
Sbjct: 161 IPIDGDFFS-----YTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTP 215
Query: 185 ASARFIVEYIPKYLDNDAVI-IIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA- 240
+A ++ I + V+ I+ G GP + SH D + +TGST IG++I +A
Sbjct: 216 LTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAG 275
Query: 241 AKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKF 300
+ +L VTLELGGKSP I AD++ V++ + F N GQ C A ++I ++F
Sbjct: 276 SSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEF 335
Query: 301 IQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPG 354
+++S R + G+ + ++ F ++ ++ + K+ GG D G
Sbjct: 336 VERSVARAKSRVVGNPFDSKTEQGPQLDETQFKKILGYINTGKQEGAKLLCGGGIAADRG 395
Query: 355 DKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEK 414
FI T+ +V I ++EIFGP++ I K I E + N L VF+
Sbjct: 396 -YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLD 454
Query: 415 VHKIFASHTSSGSICFNDTIVF 436
+ +G++ N VF
Sbjct: 455 KANYLSQALQAGTVWVNCYDVF 476
>M26760-1|AAA51694.1| 399|Homo sapiens aldehyde dehydrogenase II
protein.
Length = 399
Score = 126 bits (304), Expect = 2e-28
Identities = 99/349 (28%), Positives = 164/349 (46%), Gaps = 17/349 (4%)
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKPERP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
S L+++D + L++ D + P D DF + + H+P GV I WN+P
Sbjct: 16 SYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFS-----YTRHEPVGVCGQIIPWNFP 70
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQETTK 215
L + + A+A GN V++K +E +P +A ++ I + V+ I+ G GP
Sbjct: 71 LLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAA 130
Query: 216 LLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLELGGKSPVYIDDTADLEMTVDRIL 273
+ SH D + +TGST IG++I +A + +L VTLELGGKSP I AD++ V++
Sbjct: 131 IASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAH 190
Query: 274 WGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFS 332
+ F N GQ C A ++I ++F+ +S R + G+ + V+ F
Sbjct: 191 FALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQFK 250
Query: 333 RLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVV 387
++ ++ + K+ GG D G FI T+ +V I ++EIFGP++ I
Sbjct: 251 KILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKF 309
Query: 388 KDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTIVF 436
K I E + N L VF+ + +G++ N VF
Sbjct: 310 KTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF 358
>K03001-1|AAB59500.1| 399|Homo sapiens ALDH2 protein.
Length = 399
Score = 126 bits (304), Expect = 2e-28
Identities = 99/349 (28%), Positives = 164/349 (46%), Gaps = 17/349 (4%)
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKPERP-DRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
S L+++D + L++ D + P D DF + + H+P GV I WN+P
Sbjct: 16 SYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFS-----YTRHEPVGVCGQIIPWNFP 70
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVI-IIEG-GPQETTK 215
L + + A+A GN V++K +E +P +A ++ I + V+ I+ G GP
Sbjct: 71 LLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAA 130
Query: 216 LLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLELGGKSPVYIDDTADLEMTVDRIL 273
+ SH D + +TGST IG++I +A + +L VTLELGGKSP I AD++ V++
Sbjct: 131 IASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAH 190
Query: 274 WGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFS 332
+ F N GQ C A ++I ++F+ +S R + G+ + V+ F
Sbjct: 191 FALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQFK 250
Query: 333 RLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVV 387
++ ++ + K+ GG D G FI T+ +V I ++EIFGP++ I
Sbjct: 251 KILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFGDVQDGMTIAKEEIFGPVMQILKF 309
Query: 388 KDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTIVF 436
K I E + N L VF+ + +G++ N VF
Sbjct: 310 KTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF 358
>AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 126 bits (304), Expect = 2e-28
Identities = 117/431 (27%), Positives = 191/431 (44%), Gaps = 25/431 (5%)
Query: 23 TRNFTEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENAN 82
T N T E+ V E + + +AV+ RE + G WRR R+ A+
Sbjct: 56 TVNPTTGEVIGHVAE-GDRADVDRAVKAAREAFRLGSP----WRRMDASERGRLLNRLAD 110
Query: 83 LM-LDVLY----QDLRRSKT--ESLLLEIDYMKNDLKHVLYNLDSWTKPERPDRDFVNWL 135
L+ D +Y + L K ES L++D + ++ D W P ++
Sbjct: 111 LVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIP----MDGQ 166
Query: 136 DQVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIP 195
F H+P GV I WN+PL + +A A+A GNTV++K +E +P SA ++ I
Sbjct: 167 HFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIK 226
Query: 196 KY-LDNDAVIIIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAA-KHLTPVTLEL 251
+ V II G GP + H D + +TGST +G +I +A +L VTLEL
Sbjct: 227 EAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLEL 286
Query: 252 GGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKK 310
GGKSP + AD+E V++ F N GQ C A + I +F++++ ++ ++
Sbjct: 287 GGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQR 346
Query: 311 WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG-KYDPGDKFIDLTILTNV 366
G+ + V+ F R+ + + K+ GG ++ FI T+ V
Sbjct: 347 KVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGV 406
Query: 367 DVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSG 426
+ +I ++EIFGP+ + K I E ++ N L VF+ F +G
Sbjct: 407 QDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAG 466
Query: 427 SICFNDTIVFT 437
++ N + T
Sbjct: 467 TVWVNTYNIVT 477
>M63967-1|AAA96830.1| 517|Homo sapiens aldehyde dehydrogenase
protein.
Length = 517
Score = 126 bits (303), Expect = 2e-28
Identities = 116/427 (27%), Positives = 188/427 (44%), Gaps = 17/427 (3%)
Query: 23 TRNFTEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVT--RCLKWRRKQLRNLYRMYEEN 80
T N T E+ V E + + +AV+ RE + G R R +L NL E
Sbjct: 56 TVNPTTGEVIGHVAE-GDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVER 114
Query: 81 ANLMLDVLYQ-DLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVF 139
+ L L D + ES L++D + ++ D W P ++ F
Sbjct: 115 DRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIP----MHGQHFCF 170
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-L 198
H+P GV I WN+PL + +A A+A GNTV++K +E +P SA ++ I +
Sbjct: 171 TRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGF 230
Query: 199 DNDAVIIIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAA-KHLTPVTLELGGKS 255
V II G GP + H D + +TGST +G +I +A +L VTLELGGKS
Sbjct: 231 PPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKS 290
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGD 314
P + AD+E V++ F N GQ C A + I +F++++ ++ ++ G+
Sbjct: 291 PSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGN 350
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG-KYDPGDKFIDLTILTNVDVND 370
+ V+ F R+ + + K+ GG ++ FI T+ V +
Sbjct: 351 PFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDM 410
Query: 371 KIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICF 430
+I ++EIFGP+ + K I E ++ N L VF+ F +G++
Sbjct: 411 RIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWV 470
Query: 431 NDTIVFT 437
N + T
Sbjct: 471 NTYNIVT 477
>BT007418-1|AAP36086.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 126 bits (303), Expect = 2e-28
Identities = 116/427 (27%), Positives = 188/427 (44%), Gaps = 17/427 (3%)
Query: 23 TRNFTEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVT--RCLKWRRKQLRNLYRMYEEN 80
T N T E+ V E + + +AV+ RE + G R R +L NL E
Sbjct: 56 TVNPTTGEVIGHVAE-GDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVER 114
Query: 81 ANLMLDVLYQ-DLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVF 139
+ L L D + ES L++D + ++ D W P ++ F
Sbjct: 115 DRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIP----MDGQHFCF 170
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-L 198
H+P GV I WN+PL + +A A+A GNTV++K +E +P SA ++ I +
Sbjct: 171 TRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGF 230
Query: 199 DNDAVIIIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAA-KHLTPVTLELGGKS 255
V II G GP + H D + +TGST +G +I +A +L VTLELGGKS
Sbjct: 231 PPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKS 290
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGD 314
P + AD+E V++ F N GQ C A + I +F++++ ++ ++ G+
Sbjct: 291 PSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGN 350
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG-KYDPGDKFIDLTILTNVDVND 370
+ V+ F R+ + + K+ GG ++ FI T+ V +
Sbjct: 351 PFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDM 410
Query: 371 KIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICF 430
+I ++EIFGP+ + K I E ++ N L VF+ F +G++
Sbjct: 411 RIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWV 470
Query: 431 NDTIVFT 437
N + T
Sbjct: 471 NTYNIVT 477
>BC001619-1|AAH01619.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 126 bits (303), Expect = 2e-28
Identities = 116/427 (27%), Positives = 188/427 (44%), Gaps = 17/427 (3%)
Query: 23 TRNFTEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVT--RCLKWRRKQLRNLYRMYEEN 80
T N T E+ V E + + +AV+ RE + G R R +L NL E
Sbjct: 56 TVNPTTGEVIGHVAE-GDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVER 114
Query: 81 ANLMLDVLYQ-DLRRSKTESLLLEIDYMKNDLKHVLYNLDSWTKPERPDRDFVNWLDQVF 139
+ L L D + ES L++D + ++ D W P ++ F
Sbjct: 115 DRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIP----MDGQHFCF 170
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-L 198
H+P GV I WN+PL + +A A+A GNTV++K +E +P SA ++ I +
Sbjct: 171 TRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGF 230
Query: 199 DNDAVIIIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAA-KHLTPVTLELGGKS 255
V II G GP + H D + +TGST +G +I +A +L VTLELGGKS
Sbjct: 231 PPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKS 290
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGD 314
P + AD+E V++ F N GQ C A + I +F++++ ++ ++ G+
Sbjct: 291 PSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGN 350
Query: 315 DPQKTPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG-KYDPGDKFIDLTILTNVDVND 370
+ V+ F R+ + + K+ GG ++ FI T+ V +
Sbjct: 351 PFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDM 410
Query: 371 KIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICF 430
+I ++EIFGP+ + K I E ++ N L VF+ F +G++
Sbjct: 411 RIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWV 470
Query: 431 NDTIVFT 437
N + T
Sbjct: 471 NTYNIVT 477
>U50203-1|AAB06721.1| 466|Homo sapiens aldehyde dehydrogenase E3'
protein.
Length = 466
Score = 124 bits (298), Expect = 8e-28
Identities = 88/292 (30%), Positives = 138/292 (47%), Gaps = 14/292 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+A GN ++ KPS +P SA + E Y +
Sbjct: 117 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 176
Query: 202 AVIIIEGGPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
+++GG L H + +TGS G I +AK + PVTLELGGKSP+ I
Sbjct: 177 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIF 236
Query: 261 DTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQKT 319
D+ V L F+ GQ C V KEI +KF ++ K+ + GD +
Sbjct: 237 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLED 296
Query: 320 PDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDK------FIDLTILTNVDVN 369
++N H R+ + ++ K+ GG Y P D ++ +LTN +
Sbjct: 297 TRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDD 356
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFA 420
+++EIFGP+++I E L+ N+ L VF+ ++ H++ A
Sbjct: 357 MTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVA 408
>U34252-1|AAB18827.1| 493|Homo sapiens gamma-aminobutyraldehyde
dehydrogenase protein.
Length = 493
Score = 124 bits (298), Expect = 8e-28
Identities = 88/292 (30%), Positives = 138/292 (47%), Gaps = 14/292 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+A GN ++ KPS +P SA + E Y +
Sbjct: 144 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 203
Query: 202 AVIIIEGGPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
+++GG L H + +TGS G I +AK + PVTLELGGKSP+ I
Sbjct: 204 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIF 263
Query: 261 DTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQKT 319
D+ V L F+ GQ C V KEI +KF ++ K+ + GD +
Sbjct: 264 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLED 323
Query: 320 PDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDK------FIDLTILTNVDVN 369
++N H R+ + ++ K+ GG Y P D ++ +LTN +
Sbjct: 324 TRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDD 383
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFA 420
+++EIFGP+++I E L+ N+ L VF+ ++ H++ A
Sbjct: 384 MTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVA 435
>AL451074-5|CAH74061.1| 518|Homo sapiens aldehyde dehydrogenase 9
family, member A1 protein.
Length = 518
Score = 124 bits (298), Expect = 8e-28
Identities = 88/292 (30%), Positives = 138/292 (47%), Gaps = 14/292 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+A GN ++ KPS +P SA + E Y +
Sbjct: 169 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 228
Query: 202 AVIIIEGGPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
+++GG L H + +TGS G I +AK + PVTLELGGKSP+ I
Sbjct: 229 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIF 288
Query: 261 DTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQKT 319
D+ V L F+ GQ C V KEI +KF ++ K+ + GD +
Sbjct: 289 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLED 348
Query: 320 PDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDK------FIDLTILTNVDVN 369
++N H R+ + ++ K+ GG Y P D ++ +LTN +
Sbjct: 349 TRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDD 408
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFA 420
+++EIFGP+++I E L+ N+ L VF+ ++ H++ A
Sbjct: 409 MTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVA 460
>AF172093-1|AAF43600.1| 494|Homo sapiens
4-trimethylaminobutyraldehyde dehydrogenase protein.
Length = 494
Score = 124 bits (298), Expect = 8e-28
Identities = 88/292 (30%), Positives = 138/292 (47%), Gaps = 14/292 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+A GN ++ KPS +P SA + E Y +
Sbjct: 145 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 204
Query: 202 AVIIIEGGPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
+++GG L H + +TGS G I +AK + PVTLELGGKSP+ I
Sbjct: 205 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIF 264
Query: 261 DTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQKT 319
D+ V L F+ GQ C V KEI +KF ++ K+ + GD +
Sbjct: 265 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLED 324
Query: 320 PDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDK------FIDLTILTNVDVN 369
++N H R+ + ++ K+ GG Y P D ++ +LTN +
Sbjct: 325 TRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDD 384
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFA 420
+++EIFGP+++I E L+ N+ L VF+ ++ H++ A
Sbjct: 385 MTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVA 436
>X75425-1|CAA53176.1| 462|Homo sapiens aldehyde dehydrogenase
(NAD+) protein.
Length = 462
Score = 122 bits (293), Expect = 3e-27
Identities = 87/292 (29%), Positives = 137/292 (46%), Gaps = 14/292 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+ GN ++ KPS +P SA + E Y +
Sbjct: 113 EPLGVCVGIGAWNYPFQIASWKSAPALRCGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 172
Query: 202 AVIIIEGGPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
+++GG L H + +TGS G I +AK + PVTLELGGKSP+ I
Sbjct: 173 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIF 232
Query: 261 DTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQKT 319
D+ V L F+ GQ C V KEI +KF ++ K+ + GD +
Sbjct: 233 SDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLED 292
Query: 320 PDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDK------FIDLTILTNVDVN 369
++N H R+ + ++ K+ GG Y P D ++ +LTN +
Sbjct: 293 TRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDD 352
Query: 370 DKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFA 420
+++EIFGP+++I E L+ N+ L VF+ ++ H++ A
Sbjct: 353 MTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVA 404
>BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase 1
family, member L2 protein.
Length = 923
Score = 119 bits (287), Expect = 2e-26
Identities = 92/305 (30%), Positives = 148/305 (48%), Gaps = 13/305 (4%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYL 198
F +P GV II WNYPL + A +AAGNT+++KP++++P +A E K
Sbjct: 579 FTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAG 638
Query: 199 DNDAVI-IIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAA-KHLTPVTLELGGK 254
VI II G + LS D + +TGST IGK I S A +L V+LELGGK
Sbjct: 639 FPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGK 698
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FG 313
SP+ I + +L+ TV + F N G+ CIA + + I ++F+ + +KK G
Sbjct: 699 SPLIIFNDCELDKTVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIG 758
Query: 314 DDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK--YDPGDKFIDLTILTNVDV 368
D ++ D+ + H +L + + + GG+ PG F++ T+ T+V+
Sbjct: 759 DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPG-FFMEPTVFTDVED 817
Query: 369 NDKIMEDEIFGPLLAICVVK--DINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSG 426
+ ++E FGP++ I + DI+ L+ N L VF+ + +G
Sbjct: 818 YMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAG 877
Query: 427 SICFN 431
++ N
Sbjct: 878 TVFIN 882
>Y11192-1|CAA72076.1| 535|Homo sapiens succinic semialdehyde
dehydrogenase precursor protein.
Length = 535
Score = 115 bits (277), Expect = 3e-25
Identities = 81/311 (26%), Positives = 141/311 (45%), Gaps = 12/311 (3%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK 196
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E +
Sbjct: 187 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQ 246
Query: 197 YLDNDAVIIIEGGPQETTKLLSHRF------DYIFYTGSTNIGKIIYASAAKHLTPVTLE 250
V + ++ K + I +TGST GKI+ AA + V++E
Sbjct: 247 AGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSME 306
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK 310
LGG +P + D+A+++ V + KF N GQTC+ + L + I + F++ +KK
Sbjct: 307 LGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKK 366
Query: 311 --WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK-YDPGDKFIDLTILT 364
G+ ++ ++N + +++ ++ + K + GGK + G F + T+L
Sbjct: 367 NLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLC 426
Query: 365 NVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTS 424
NV + +E FGPL + EA+ N L Y +S A
Sbjct: 427 NVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLE 486
Query: 425 SGSICFNDTIV 435
G + N+ ++
Sbjct: 487 VGMVGVNEGLI 497
>BC034321-1|AAH34321.1| 535|Homo sapiens aldehyde dehydrogenase 5
family, member A1 (succinate-semialdehyde dehydrogenas
protein.
Length = 535
Score = 115 bits (277), Expect = 3e-25
Identities = 81/311 (26%), Positives = 141/311 (45%), Gaps = 12/311 (3%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK 196
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E +
Sbjct: 187 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQ 246
Query: 197 YLDNDAVIIIEGGPQETTKLLSHRF------DYIFYTGSTNIGKIIYASAAKHLTPVTLE 250
V + ++ K + I +TGST GKI+ AA + V++E
Sbjct: 247 AGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSME 306
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK 310
LGG +P + D+A+++ V + KF N GQTC+ + L + I + F++ +KK
Sbjct: 307 LGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKK 366
Query: 311 --WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK-YDPGDKFIDLTILT 364
G+ ++ ++N + +++ ++ + K + GGK + G F + T+L
Sbjct: 367 NLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLC 426
Query: 365 NVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTS 424
NV + +E FGPL + EA+ N L Y +S A
Sbjct: 427 NVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLE 486
Query: 425 SGSICFNDTIV 435
G + N+ ++
Sbjct: 487 VGMVGVNEGLI 497
>AL031230-4|CAA20248.1| 535|Homo sapiens aldehyde dehydrogenase 5
family, member A1 (succinate-semialdehyde dehydrogenas
protein.
Length = 535
Score = 115 bits (277), Expect = 3e-25
Identities = 81/311 (26%), Positives = 141/311 (45%), Gaps = 12/311 (3%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK 196
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E +
Sbjct: 187 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQ 246
Query: 197 YLDNDAVIIIEGGPQETTKLLSHRF------DYIFYTGSTNIGKIIYASAAKHLTPVTLE 250
V + ++ K + I +TGST GKI+ AA + V++E
Sbjct: 247 AGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSME 306
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK 310
LGG +P + D+A+++ V + KF N GQTC+ + L + I + F++ +KK
Sbjct: 307 LGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKK 366
Query: 311 --WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK-YDPGDKFIDLTILT 364
G+ ++ ++N + +++ ++ + K + GGK + G F + T+L
Sbjct: 367 NLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLC 426
Query: 365 NVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTS 424
NV + +E FGPL + EA+ N L Y +S A
Sbjct: 427 NVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLE 486
Query: 425 SGSICFNDTIV 435
G + N+ ++
Sbjct: 487 VGMVGVNEGLI 497
>AJ427355-1|CAD20884.1| 535|Homo sapiens succinic semialdehyde
dehydrogenase precursor protein.
Length = 535
Score = 115 bits (277), Expect = 3e-25
Identities = 81/311 (26%), Positives = 141/311 (45%), Gaps = 12/311 (3%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK 196
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E +
Sbjct: 187 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQ 246
Query: 197 YLDNDAVIIIEGGPQETTKLLSHRF------DYIFYTGSTNIGKIIYASAAKHLTPVTLE 250
V + ++ K + I +TGST GKI+ AA + V++E
Sbjct: 247 AGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSME 306
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK 310
LGG +P + D+A+++ V + KF N GQTC+ + L + I + F++ +KK
Sbjct: 307 LGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKK 366
Query: 311 --WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK-YDPGDKFIDLTILT 364
G+ ++ ++N + +++ ++ + K + GGK + G F + T+L
Sbjct: 367 NLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLC 426
Query: 365 NVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTS 424
NV + +E FGPL + EA+ N L Y +S A
Sbjct: 427 NVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLE 486
Query: 425 SGSICFNDTIV 435
G + N+ ++
Sbjct: 487 VGMVGVNEGLI 497
>BC113862-1|AAI13863.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 113 bits (272), Expect = 1e-24
Identities = 103/411 (25%), Positives = 184/411 (44%), Gaps = 24/411 (5%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FGDDPQKTPDYSRIVNNRHFSR 333
F N G+ C+ + K I +F+++ +KW G +++ H +
Sbjct: 278 SSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEK 337
Query: 334 L-----QAVLDASR-------HKIAIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPL 381
+ +A+ + ++ K+++ + G F+ T++T++ M +EIFGP+
Sbjct: 338 VRSYVKRALAEGAQIWCGEGVDKLSLPARNQAG-YFMLPTVITDIKDESCCMTEEIFGPV 396
Query: 382 LAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSICFN 431
+ E ++ N L V+SS+ +VH++ A SG + N
Sbjct: 397 TCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRV-AKKLQSGLVWTN 446
>AL445190-1|CAI95158.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 113 bits (272), Expect = 1e-24
Identities = 103/411 (25%), Positives = 184/411 (44%), Gaps = 24/411 (5%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FGDDPQKTPDYSRIVNNRHFSR 333
F N G+ C+ + K I +F+++ +KW G +++ H +
Sbjct: 278 SSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEK 337
Query: 334 L-----QAVLDASR-------HKIAIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPL 381
+ +A+ + ++ K+++ + G F+ T++T++ M +EIFGP+
Sbjct: 338 VRSYVKRALAEGAQIWCGEGVDKLSLPARNQAG-YFMLPTVITDIKDESCCMTEEIFGPV 396
Query: 382 LAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSICFN 431
+ E ++ N L V+SS+ +VH++ A SG + N
Sbjct: 397 TCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRV-AKKLQSGLVWTN 446
>AL021939-1|CAI20305.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 113 bits (272), Expect = 1e-24
Identities = 103/411 (25%), Positives = 184/411 (44%), Gaps = 24/411 (5%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FGDDPQKTPDYSRIVNNRHFSR 333
F N G+ C+ + K I +F+++ +KW G +++ H +
Sbjct: 278 SSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEK 337
Query: 334 L-----QAVLDASR-------HKIAIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPL 381
+ +A+ + ++ K+++ + G F+ T++T++ M +EIFGP+
Sbjct: 338 VRSYVKRALAEGAQIWCGEGVDKLSLPARNQAG-YFMLPTVITDIKDESCCMTEEIFGPV 396
Query: 382 LAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSICFN 431
+ E ++ N L V+SS+ +VH++ A SG + N
Sbjct: 397 TCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRV-AKKLQSGLVWTN 446
>AF303134-1|AAG42417.1| 487|Homo sapiens aldehyde dehydrogenase 12
protein.
Length = 487
Score = 113 bits (272), Expect = 1e-24
Identities = 103/411 (25%), Positives = 184/411 (44%), Gaps = 24/411 (5%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FGDDPQKTPDYSRIVNNRHFSR 333
F N G+ C+ + K I +F+++ +KW G +++ H +
Sbjct: 278 SSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEK 337
Query: 334 L-----QAVLDASR-------HKIAIGGKYDPGDKFIDLTILTNVDVNDKIMEDEIFGPL 381
+ +A+ + ++ K+++ + G F+ T++T++ M +EIFGP+
Sbjct: 338 VRSYVKRALAEGAQIWCGEGVDKLSLPARNQAG-YFMLPTVITDIKDESCCMTEEIFGPV 396
Query: 382 LAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSICFN 431
+ E ++ N L V+SS+ +VH++ A SG + N
Sbjct: 397 TCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRV-AKKLQSGLVWTN 446
>AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 110 bits (265), Expect = 8e-24
Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 9/251 (3%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV II WNYPL + A +AAGNTV++KP++++P +A E K +
Sbjct: 562 EPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKG 621
Query: 202 AVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAA-KHLTPVTLELGGKSPVY 258
V ++ G + LS D I +TGST +GK I S A ++ V+LELGGKSP+
Sbjct: 622 VVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLI 681
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQ 317
I DL V + F N G+ CIA + I ++F+++ + + K G+
Sbjct: 682 IFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLD 741
Query: 318 KTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGKYDPGDK-FIDLTILTNVDVNDKIM 373
+ D+ ++ H +L + + GG P F + T+ T+V+ + I
Sbjct: 742 RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIA 801
Query: 374 EDEIFGPLLAI 384
++E FGP++ I
Sbjct: 802 KEESFGPVMII 812
>AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 110 bits (265), Expect = 8e-24
Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 9/251 (3%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV II WNYPL + A +AAGNTV++KP++++P +A E K +
Sbjct: 562 EPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKG 621
Query: 202 AVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAA-KHLTPVTLELGGKSPVY 258
V ++ G + LS D I +TGST +GK I S A ++ V+LELGGKSP+
Sbjct: 622 VVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLI 681
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQ 317
I DL V + F N G+ CIA + I ++F+++ + + K G+
Sbjct: 682 IFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLD 741
Query: 318 KTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGKYDPGDK-FIDLTILTNVDVNDKIM 373
+ D+ ++ H +L + + GG P F + T+ T+V+ + I
Sbjct: 742 RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIA 801
Query: 374 EDEIFGPLLAI 384
++E FGP++ I
Sbjct: 802 KEESFGPVMII 812
>AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase 1
family, member L1 variant protein.
Length = 954
Score = 110 bits (264), Expect = 1e-23
Identities = 77/251 (30%), Positives = 123/251 (49%), Gaps = 9/251 (3%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV II WNYPL + A +AAGNTV++KP++++P +A E K +
Sbjct: 614 EPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKG 673
Query: 202 AVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAA-KHLTPVTLELGGKSPVY 258
V ++ G + LS D I +TGST +GK I S A ++ V+LELGGKSP+
Sbjct: 674 VVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLI 733
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQ 317
I DL V + F N G+ CIA + I ++F+++ + + K G+
Sbjct: 734 IFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLD 793
Query: 318 KTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGKYDPGDK-FIDLTILTNVDVNDKIM 373
+ D+ ++ H +L + + GG P F + T+ T V+ + I
Sbjct: 794 RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTGVEDHMFIA 853
Query: 374 EDEIFGPLLAI 384
++E FGP++ I
Sbjct: 854 KEESFGPVMII 864
>AJ427354-1|CAD20883.2| 480|Homo sapiens succinic semialdehyde
dehydrogenase protein.
Length = 480
Score = 109 bits (263), Expect = 1e-23
Identities = 85/324 (26%), Positives = 146/324 (45%), Gaps = 25/324 (7%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK 196
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E
Sbjct: 119 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEVNQG 178
Query: 197 YL-DNDAVIIIE--GGPQETTKLL--SHR--------------FDYIFYTGSTNIGKIIY 237
+L D D +++ G P ++ S + I +TGST GKI+
Sbjct: 179 FLLDLDPLLLASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILL 238
Query: 238 ASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQ 297
AA + V++ELGG +P + D+A+++ V + KF N GQTC+ + L + I
Sbjct: 239 HHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIH 298
Query: 298 EKFIQKSKRILKK--WFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK-Y 351
+ F++ +KK G ++ ++N + +++ ++ + K + GGK +
Sbjct: 299 DAFVKAFAEAMKKNLRVGSGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRH 358
Query: 352 DPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSS 411
G F + T+L NV + +E FGPL + EA+ N L Y +S
Sbjct: 359 QLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQ 418
Query: 412 SEKVHKIFASHTSSGSICFNDTIV 435
A G + N+ ++
Sbjct: 419 DPAQIWRVAEQLEVGMVGVNEGLI 442
>BX538027-1|CAD97973.1| 416|Homo sapiens hypothetical protein
protein.
Length = 416
Score = 106 bits (255), Expect = 1e-22
Identities = 74/238 (31%), Positives = 124/238 (52%), Gaps = 10/238 (4%)
Query: 203 VIIIEG-GPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVYI 259
V I+ G GP + SH + + I +TGST +GK++ +A++ +L VTLELGGK+P +
Sbjct: 134 VNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIV 193
Query: 260 DDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKKW-FGDDPQK 318
ADL++ V+ G F N GQ C A V +++ +F+++S KK GD
Sbjct: 194 CADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDV 253
Query: 319 TPDYSRIVNNRHFSRLQAVLDASRH---KIAIGGK-YDPGDKFIDLTILTNVDVNDKIME 374
+ ++ + F ++ ++++ + K+ GG + FI T+ + V N +I +
Sbjct: 254 KTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAK 313
Query: 375 DEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSS-EKVHKIFASHTSSGSICFN 431
+EIFGP+ I K I E +K N L VF+ + +K K+ AS SG++ N
Sbjct: 314 EEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKL-ASALESGTVWIN 370
>AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofolate
dehydrogenase protein.
Length = 902
Score = 106 bits (254), Expect = 2e-22
Identities = 75/251 (29%), Positives = 123/251 (49%), Gaps = 9/251 (3%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV II WNYPL + A +AAGNTV++KP++++P +A E K +
Sbjct: 562 EPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKG 621
Query: 202 AVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAA-KHLTPVTLELGGKSPVY 258
V ++ G + LS D I +TGST +GK I S A ++ V+LELGG+SP
Sbjct: 622 VVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGESPFI 681
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK-SKRILKKWFGDDPQ 317
I DL V + F + G+ CIA + I ++F+++ + + K G+
Sbjct: 682 IFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLD 741
Query: 318 KTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGKYDPGDK-FIDLTILTNVDVNDKIM 373
+ D+ ++ H +L + + GG P F + T+ T+V+ + I
Sbjct: 742 RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIA 801
Query: 374 EDEIFGPLLAI 384
++E FGP++ I
Sbjct: 802 KEESFGPVMII 812
>AB209821-1|BAD93058.1| 330|Homo sapiens aldehyde dehydrogenase 1A1
variant protein.
Length = 330
Score = 105 bits (252), Expect = 3e-22
Identities = 87/274 (31%), Positives = 131/274 (47%), Gaps = 15/274 (5%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 59 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 112
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 113 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 171
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 172 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 231
Query: 202 AVIIIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASAAK-HLTPVTLELGGKSPVY 258
V I+ G GP + SH D + +TGST +GK+I +A K +L VTLELGGKSP
Sbjct: 232 VVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCI 291
Query: 259 IDDTADLEMTVDRILWGKFINAGQTCIAPDYVLC 292
+ ADL+ V+ G F + GQ CIA + C
Sbjct: 292 VLADADLDNAVEFAHHGVFYHQGQCCIAASRIFC 325
>BC103935-1|AAI03936.1| 488|Homo sapiens ALDH1L2 protein protein.
Length = 488
Score = 97.5 bits (232), Expect = 8e-20
Identities = 58/169 (34%), Positives = 91/169 (53%), Gaps = 4/169 (2%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASA-RFIVEYIPKY 197
F +P GV II WNYPL + A +AAGNT+++KP++++P +A +F +
Sbjct: 317 FTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAG 376
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGK-IIYASAAKHLTPVTLELGGK 254
+ II G + LS D + +TGST IGK I+ + A +L V+LELGGK
Sbjct: 377 FPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGK 436
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK 303
SP+ I + +L+ V + F N G+ CIA + + I ++F+ +
Sbjct: 437 SPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTR 485
>AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ38508 fis, clone HCHON2000322, moderately
similar to 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (EC
1.5.1.6). ).
Length = 752
Score = 97.5 bits (232), Expect = 8e-20
Identities = 58/169 (34%), Positives = 91/169 (53%), Gaps = 4/169 (2%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASA-RFIVEYIPKY 197
F +P GV II WNYPL + A +AAGNT+++KP++++P +A +F +
Sbjct: 579 FTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAG 638
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGK-IIYASAAKHLTPVTLELGGK 254
+ II G + LS D + +TGST IGK I+ + A +L V+LELGGK
Sbjct: 639 FPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGK 698
Query: 255 SPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQK 303
SP+ I + +L+ V + F N G+ CIA + + I ++F+ +
Sbjct: 699 SPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTR 747
>L34820-1|AAA67057.1| 323|Homo sapiens succinate semialdehyde
dehydrogenase protein.
Length = 323
Score = 97.1 bits (231), Expect = 1e-19
Identities = 73/283 (25%), Positives = 128/283 (45%), Gaps = 12/283 (4%)
Query: 165 MAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDAVIIIEGGPQETTKLLSHRF--- 221
+ A+AAG TV+VKP+E +P SA + E + V + ++ K +
Sbjct: 3 VGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTD 62
Query: 222 ---DYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFI 278
I +TGST GKI+ AA + V++ELGG +P + D+A+++ V + KF
Sbjct: 63 PLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFR 122
Query: 279 NAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK--WFGDDPQKTPDYSRIVNNRHFSRLQA 336
N GQTC+ + L + I + F++ +KK G+ ++ ++N + +++
Sbjct: 123 NTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEK 182
Query: 337 VLDASRHK---IAIGGK-YDPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINE 392
++ + K + GGK + G F + T+L NV + +E FGPL + E
Sbjct: 183 QVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEE 242
Query: 393 ALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSICFNDTIV 435
A+ N L Y +S A G + N+ ++
Sbjct: 243 AIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLI 285
>BC030589-1|AAH30589.1| 480|Homo sapiens aldehyde dehydrogenase 1
family, member A2 protein.
Length = 480
Score = 91.5 bits (217), Expect = 5e-18
Identities = 63/207 (30%), Positives = 109/207 (52%), Gaps = 8/207 (3%)
Query: 232 IGKIIYASAAK-HLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYV 290
+GK+I +A + +L VTLELGGKSP I ADL+ V++ G F N GQ C A +
Sbjct: 229 VGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 288
Query: 291 LCTKEIQEKFIQKS-KRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLD---ASRHKIA 346
+ I E+F+++S +R ++ G T + ++ + ++++ ++ A K+
Sbjct: 289 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 348
Query: 347 IGGKYDPGDK--FIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPL 404
GGK G K FI+ T+ +NV + +I ++EIFGP+ I K ++E ++ N L
Sbjct: 349 CGGK-GLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 407
Query: 405 VLYVFSSSEKVHKIFASHTSSGSICFN 431
V VF++ +S +G++ N
Sbjct: 408 VAAVFTNDINKALTVSSAMQAGTVWIN 434
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/52 (42%), Positives = 33/52 (63%)
Query: 139 FIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFI 190
F H+P GV I WN+PL + +A A+ GNTV++KP+E +P SA ++
Sbjct: 171 FTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYM 222
>M93405-1|AAA36328.1| 430|Homo sapiens methylmalonate semialdehyde
dehydrogenase protein.
Length = 430
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 64 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 123
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 124 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 183
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 184 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 242
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 243 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 299
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 300 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 359
Query: 424 SSGSICFN 431
G + N
Sbjct: 360 DVGQVGVN 367
>BC032371-1|AAH32371.1| 535|Homo sapiens aldehyde dehydrogenase 6
family, member A1 protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>BC004909-1|AAH04909.1| 535|Homo sapiens aldehyde dehydrogenase 6
family, member A1 protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AJ249994-1|CAB76468.1| 535|Homo sapiens methylmalonate
semialdehyde dehydrogenase protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AF159889-1|AAF80380.1| 535|Homo sapiens methylmalonate
semialdehyde dehydrogenase protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AF148855-1|AAG29581.1| 535|Homo sapiens
methylmalonate-semialdehyde dehydrogenase protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AF148505-1|AAF04489.1| 535|Homo sapiens
methylmalonate-semialdehyde dehydrogenase protein.
Length = 535
Score = 89.8 bits (213), Expect = 2e-17
Identities = 72/308 (23%), Positives = 141/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AK222687-1|BAD96407.1| 535|Homo sapiens aldehyde dehydrogenase 6A1
precursor variant protein.
Length = 535
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/308 (23%), Positives = 140/308 (45%), Gaps = 18/308 (5%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRILKKWF 312
+ A+ E T+++++ F AGQ C+A + E ++ + + +K L+
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVDHAKN-LRVNA 347
Query: 313 GDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGK------YDPGDKFIDLTIL 363
GD P D ++ + R+ ++D+ + I + G+ Y+ G+ F+ TI+
Sbjct: 348 GDQPGA--DLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGN-FVGPTII 404
Query: 364 TNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHT 423
+NV N ++EIFGP+L + + ++EA++ +N +F+++ + +A
Sbjct: 405 SNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLV 464
Query: 424 SSGSICFN 431
G + N
Sbjct: 465 DVGQVGVN 472
>AK223244-1|BAD96964.1| 535|Homo sapiens aldehyde dehydrogenase 6A1
precursor variant protein.
Length = 535
Score = 87.4 bits (207), Expect = 9e-17
Identities = 74/306 (24%), Positives = 137/306 (44%), Gaps = 14/306 (4%)
Query: 138 VFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY 197
++ Y P GV I +N+P + L A+ GNT ++KPSE P + + + +
Sbjct: 169 LYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDS 228
Query: 198 LDNDAVIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELGGKS 255
D + I G E + D I + GS G+ I+ ++H V +G K+
Sbjct: 229 GAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKN 288
Query: 256 PVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQE---KFIQKSKRI---LK 309
+ A+ E T+++++ F AGQ C+A + E ++ + ++ +K + +
Sbjct: 289 HGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAR 348
Query: 310 KWFGDD--PQKTPDYSRIVNNRHFSRLQ--AVLDASRHKIAIGGKYDPGDKFIDLTILTN 365
G D P TP V N S + A + KI + G Y+ G+ F+ TI++N
Sbjct: 349 DQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKG-YENGN-FVGPTIISN 406
Query: 366 VDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSS 425
V N ++EIFGP+L + + ++E ++ +N +F+++ + +A
Sbjct: 407 VKPNMTCYKEEIFGPVLVVLETETLDEVIQIVNNNPYGNGTAIFTTNGATARKYAHLVDV 466
Query: 426 GSICFN 431
G + N
Sbjct: 467 GQVGVN 472
>M54931-1|AAA62825.1| 287|Homo sapiens aldehyde dehydrogenase I
protein.
Length = 287
Score = 86.6 bits (205), Expect = 2e-16
Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 10/196 (5%)
Query: 203 VIIIEG-GPQETTKLLSHR-FDYIFYTGSTNIGKIIYASA-AKHLTPVTLELGGKSPVYI 259
V I+ G GP + SH D + +TGST IG++I +A + +L VTLELGGKSP I
Sbjct: 22 VNIVPGFGPTAGPAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNII 81
Query: 260 DDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKS-KRILKKWFGDDPQK 318
AD++ V++ + F N GQ C A ++I ++F+ +S R + G+
Sbjct: 82 MSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDS 141
Query: 319 TPDYSRIVNNRHFSRLQAVLDASRH---KIAIGG--KYDPGDKFIDLTILTNVDVNDKIM 373
+ V+ F ++ ++ + K+ GG D G FI T+ +V I
Sbjct: 142 KTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRG-YFIQPTVFGDVQDGMTIA 200
Query: 374 EDEIFGPLLAICVVKD 389
++EIFGP++ I V+D
Sbjct: 201 KEEIFGPVMQILEVQD 216
>BC014168-1|AAH14168.2| 159|Homo sapiens ALDH3B1 protein protein.
Length = 159
Score = 82.6 bits (195), Expect = 2e-15
Identities = 38/81 (46%), Positives = 55/81 (67%)
Query: 352 DPGDKFIDLTILTNVDVNDKIMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSS 411
D D++I T+L +V + +M++EIFGP+L I V+ ++EA++FIN R KPL LY FS+
Sbjct: 1 DESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSN 60
Query: 412 SEKVHKIFASHTSSGSICFND 432
S +V K + TSSG C ND
Sbjct: 61 SSQVVKRVLTQTSSGGFCGND 81
>AL445190-2|CAI95159.1| 433|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 433
Score = 82.2 bits (194), Expect = 3e-15
Identities = 70/245 (28%), Positives = 113/245 (46%), Gaps = 8/245 (3%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFIN 279
F N
Sbjct: 278 SSFAN 282
>AL021939-2|CAI20306.1| 433|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 433
Score = 82.2 bits (194), Expect = 3e-15
Identities = 70/245 (28%), Positives = 113/245 (46%), Gaps = 8/245 (3%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++LELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFIN 279
F N
Sbjct: 278 SSFAN 282
>AK222848-1|BAD96568.1| 433|Homo sapiens aldehyde dehydrogenase 8A1
isoform 2 variant protein.
Length = 433
Score = 79.4 bits (187), Expect = 2e-14
Identities = 69/245 (28%), Positives = 112/245 (45%), Gaps = 8/245 (3%)
Query: 39 SNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRRSKTE 98
S E AV+ RE + S +R + R + L + + E++ +D + KT
Sbjct: 42 SGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKD--QGKTL 99
Query: 99 SLLLEIDYMKNDLKHVLYNLDSWTKP-ERPDRDFVNWLDQVFIYHDPYGVVLIIGAWNYP 157
+L +D ++ + S E D + + + P GV +I WN P
Sbjct: 100 ALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH--YTVRAPVGVAGLISPWNLP 157
Query: 158 LALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTK 215
L L +A A+AAGNTVI KPSE++ +A + + + K + V I+ G GP+
Sbjct: 158 LYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEA 217
Query: 216 LLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILW 274
L+SH I +TGS + I +A H ++ ELGGK+P I + A+L+ + +
Sbjct: 218 LVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSPELGGKNPAIIFEDANLDECIPATVR 277
Query: 275 GKFIN 279
F N
Sbjct: 278 SSFAN 282
>S74728-1|AAB31966.1| 511|Homo sapiens antiquitin protein.
Length = 511
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/298 (24%), Positives = 131/298 (43%), Gaps = 13/298 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P G+V II A+N+P+A+ A A+ GN + K + + + + + I K L+++
Sbjct: 155 NPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNK 214
Query: 203 V------IIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSP 256
+ + G T R + + +TGST +GK + + LELGG +
Sbjct: 215 LPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNA 274
Query: 257 VYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK-WFGDD 315
+ + ADL + V L+ AGQ C + + I ++ + + K+ + G+
Sbjct: 275 IIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNP 334
Query: 316 PQKTPDYSRIVNNRHFSR-LQAVLDASRH--KIAIGGK-YDPGDKFIDLTILTNVDVNDK 371
Y + + S L AV +A + + GGK D +++ TI+T + +
Sbjct: 335 WDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDAS 394
Query: 372 IMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSIC 429
I E F P+L + K+ E + NE + L +F ++ + +IF GS C
Sbjct: 395 IAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIF--TKDLGRIFRWLGPKGSDC 450
>BC073174-1|AAH73174.1| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/298 (24%), Positives = 131/298 (43%), Gaps = 13/298 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P G+V II A+N+P+A+ A A+ GN + K + + + + + I K L+++
Sbjct: 155 NPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNK 214
Query: 203 V------IIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSP 256
+ + G T R + + +TGST +GK + + LELGG +
Sbjct: 215 LPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNA 274
Query: 257 VYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK-WFGDD 315
+ + ADL + V L+ AGQ C + + I ++ + + K+ + G+
Sbjct: 275 IIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNP 334
Query: 316 PQKTPDYSRIVNNRHFSR-LQAVLDASRH--KIAIGGK-YDPGDKFIDLTILTNVDVNDK 371
Y + + S L AV +A + + GGK D +++ TI+T + +
Sbjct: 335 WDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDAS 394
Query: 372 IMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSIC 429
I E F P+L + K+ E + NE + L +F ++ + +IF GS C
Sbjct: 395 IAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIF--TKDLGRIFRWLGPKGSDC 450
>BC071712-1|AAH71712.1| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/298 (24%), Positives = 131/298 (43%), Gaps = 13/298 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P G+V II A+N+P+A+ A A+ GN + K + + + + + I K L+++
Sbjct: 155 NPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNK 214
Query: 203 V------IIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSP 256
+ + G T R + + +TGST +GK + + LELGG +
Sbjct: 215 LPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNA 274
Query: 257 VYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK-WFGDD 315
+ + ADL + V L+ AGQ C + + I ++ + + K+ + G+
Sbjct: 275 IIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNP 334
Query: 316 PQKTPDYSRIVNNRHFSR-LQAVLDASRH--KIAIGGK-YDPGDKFIDLTILTNVDVNDK 371
Y + + S L AV +A + + GGK D +++ TI+T + +
Sbjct: 335 WDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDAS 394
Query: 372 IMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSIC 429
I E F P+L + K+ E + NE + L +F ++ + +IF GS C
Sbjct: 395 IAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIF--TKDLGRIFRWLGPKGSDC 450
>BC002515-1|AAH02515.3| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/298 (23%), Positives = 131/298 (43%), Gaps = 13/298 (4%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P G+V II A+N+P+A+ A A+ GN + K + + + + + I K L+++
Sbjct: 155 NPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNK 214
Query: 203 V------IIIEGGPQETTKLLSHRFDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSP 256
+ + G T R + + +TGST +GK + + LELGG +
Sbjct: 215 LPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNA 274
Query: 257 VYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEKFIQKSKRILKK-WFGDD 315
+ + ADL + V L+ AGQ C + + I ++ + + K+ + G+
Sbjct: 275 IIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNP 334
Query: 316 PQKTPDYSRIVNNRHFSR-LQAVLDASRH--KIAIGGK-YDPGDKFIDLTILTNVDVNDK 371
Y + + S L AV +A + + GGK D +++ TI+T + +
Sbjct: 335 WDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDAS 394
Query: 372 IMEDEIFGPLLAICVVKDINEALKFINERGKPLVLYVFSSSEKVHKIFASHTSSGSIC 429
I E F P+L + ++ E + NE + L +F ++ + +IF GS C
Sbjct: 395 IAHTETFAPILYVFKFQNEEEVFAWNNEVKQGLSSSIF--TKDLGRIFRWLGPKGSDC 450
>BC070030-1|AAH70030.1| 253|Homo sapiens ALDH9A1 protein protein.
Length = 253
Score = 64.9 bits (151), Expect = 5e-10
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE-YIPKYLDND 201
+P GV + IGAWNYP ++ A A+A GN ++ KPS +P SA + E Y +
Sbjct: 145 EPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPG 204
Query: 202 AVIIIEGGPQETTKLLSH-RFDYIFYTGSTNIGKIIYASAAKHLTPVTL 249
+++GG L H + +TGS G I +AK + PVTL
Sbjct: 205 LFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTL 253
>BC114473-1|AAI14474.1| 265|Homo sapiens ALDH8A1 protein protein.
Length = 265
Score = 60.9 bits (141), Expect = 9e-09
Identities = 40/114 (35%), Positives = 62/114 (54%), Gaps = 3/114 (2%)
Query: 169 IAAGNTVIVKPSEISPASARFIVEYIPKY-LDNDAVIIIEG-GPQETTKLLSH-RFDYIF 225
+AAGNTVI KPSE++ +A + + + K + V I+ G GP+ L+SH I
Sbjct: 1 MAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLIS 60
Query: 226 YTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFIN 279
+TGS + I +A H ++LELGGK+P I + A+L+ + + F N
Sbjct: 61 FTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFAN 114
>BC007581-1|AAH07581.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 60.9 bits (141), Expect = 9e-09
Identities = 74/280 (26%), Positives = 127/280 (45%), Gaps = 25/280 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD--INEALKFIN 398
I+ + D + IM++EIFGP+L++ V D E L+ I+
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLID 471
>U24267-1|AAC50501.1| 563|Homo sapiens pyrroline-5-carboxylate
dehydrogenase protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>U24266-1|AAC50500.1| 563|Homo sapiens pyrroline-5-carboxylate
dehydrogenase protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>BC023600-1|AAH23600.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>AL954340-2|CAI39493.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>AL080251-1|CAI23417.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IK---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>AK222486-1|BAD96206.1| 563|Homo sapiens aldehyde dehydrogenase 4A1
precursor variant protein.
Length = 563
Score = 60.5 bits (140), Expect = 1e-08
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 140 IYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPK--Y 197
+Y G V I +N+ L A A+ GN V+ KPS+ + ++ + + +
Sbjct: 196 VYRGLEGFVAAISPFNFTAIGGNLAGAPALI-GNVVLWKPSDTAMLASYAVYRILREAGL 254
Query: 198 LDNDAVIIIEGGPQ-ETTKLLSHRFDYIFYTGSTNIGKIIYASAAK-----HLTP-VTLE 250
N + GP T S I +TGS K ++ A+ H P + E
Sbjct: 255 PPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGE 314
Query: 251 LGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPD--YVLCT--KEIQEKFIQKSKR 306
GGK+ ++ +AD+E V L F GQ C A YV + +I+ + +++ R
Sbjct: 315 CGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSR 374
Query: 307 ILKKWFGDDPQKTPDY-SRIVNNRHFSRLQAVLDASRHK----IAIGGKYDPG-DKFIDL 360
I GD + + S +++ + F+R++ L+ +R I GGK D F++
Sbjct: 375 IR---VGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEP 431
Query: 361 TILTNVDVNDKIMEDEIFGPLLAICVVKD 389
I+ + D + IM++EIFGP+L++ V D
Sbjct: 432 CIVESKDPQEPIMKEEIFGPVLSVYVYPD 460
>AK124908-1|BAC85992.1| 470|Homo sapiens protein ( Homo sapiens
cDNA FLJ42918 fis, clone BRHIP3027137, highly similar
to 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6).
).
Length = 470
Score = 58.0 bits (134), Expect = 6e-08
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 5/150 (3%)
Query: 240 AAKHLTPVTLELGGKSPVYIDDTADLEMTVDRILWGKFINAGQTCIAPDYVLCTKEIQEK 299
A ++ V+LELGGKSP+ I DL V + F N G+ CIA + I ++
Sbjct: 198 AISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDE 257
Query: 300 FIQK-SKRILKKWFGDDPQKTPDYSRIVNNRHFSRLQAVLDASRHK---IAIGGKYDPGD 355
F+++ + + K G+ + D+ ++ H +L + + GG P
Sbjct: 258 FVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRP 317
Query: 356 K-FIDLTILTNVDVNDKIMEDEIFGPLLAI 384
F + T+ T+V+ + I ++E FGP++ I
Sbjct: 318 GFFFEPTVFTDVEDHMFIAKEESFGPVMII 347
>AL591031-3|CAI12260.1| 238|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 238
Score = 51.6 bits (118), Expect = 5e-06
Identities = 54/199 (27%), Positives = 87/199 (43%), Gaps = 13/199 (6%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKY-LDND 201
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I +
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPG 217
Query: 202 AVIIIEG-GPQETTKLLSH 219
V I+ G GP + SH
Sbjct: 218 VVNIVPGYGPTAGAAISSH 236
>AL591031-2|CAI12259.1| 230|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 230
Score = 49.6 bits (113), Expect = 2e-05
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 11/172 (6%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYI 194
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A + I
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLI 209
>AJ427353-1|CAD20882.1| 222|Homo sapiens succinate semialdehyde
dehydrogenase protein.
Length = 222
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/56 (39%), Positives = 33/56 (58%)
Query: 137 QVFIYHDPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVE 192
+ + P GV +I WN+P A+ + A+AAG TV+VKP+E +P SA + E
Sbjct: 119 RALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAE 174
>AL591031-4|CAI12261.1| 203|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 203
Score = 48.4 bits (110), Expect = 5e-05
Identities = 46/165 (27%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 27 TEAEIRQSVEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLM-L 85
TE E+ Q VEE + ++ +AV+ R+ + G WR R+ + A+L+
Sbjct: 45 TEEELCQ-VEE-GDKEDVDKAVKAARQAFQIGSP----WRTMDASERGRLLYKLADLIER 98
Query: 86 DVLYQDLRRSKTESLLLEIDYMKNDLKHVLYNLD---SWTKPERPDRDFVNWLDQVFIYH 142
D L S L Y+ NDL + L W + ++ + H
Sbjct: 99 DRLLLATMESMNGGKLYSNAYL-NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRH 157
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASA 187
+P GV I WN+PL + + + A++ GNTV+VKP+E +P +A
Sbjct: 158 EPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTA 202
>BC042142-1|AAH42142.1| 481|Homo sapiens ALDH16A1 protein protein.
Length = 481
Score = 41.9 bits (94), Expect = 0.004
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV+ ++ +PL + +A A+A GNTV++ PS P A + + +
Sbjct: 338 EPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAGL 397
Query: 203 VIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELG 252
++ G T+ L+ D ++Y GS + + ++A +L PV G
Sbjct: 398 ANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRG 449
>BC035641-1|AAH35641.1| 216|Homo sapiens ALDH16A1 protein protein.
Length = 216
Score = 41.9 bits (94), Expect = 0.004
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV+ ++ +PL + +A A+A GNTV++ PS P A + + +
Sbjct: 73 EPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAGL 132
Query: 203 VIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELG 252
++ G T+ L+ D ++Y GS + + ++A +L PV G
Sbjct: 133 ANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRG 184
>BC014895-1|AAH14895.2| 802|Homo sapiens aldehyde dehydrogenase 16
family, member A1 protein.
Length = 802
Score = 41.9 bits (94), Expect = 0.004
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV+ ++ +PL + +A A+A GNTV++ PS P A + + +
Sbjct: 659 EPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATVFPAGL 718
Query: 203 VIIIEGGPQETTKLLSHRFDY--IFYTGSTNIGKIIYASAAKHLTPVTLELG 252
++ G T+ L+ D ++Y GS + + ++A +L PV G
Sbjct: 719 ANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWASAGNLKPVWASRG 770
Score = 36.7 bits (81), Expect = 0.16
Identities = 28/133 (21%), Positives = 59/133 (44%), Gaps = 3/133 (2%)
Query: 143 DPYGVVLIIGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFIVEYIPKYLDNDA 202
+P GV+ +I + + + A+A G TV+ SPA + + +
Sbjct: 164 EPMGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPL-LLAQLAGELGPFPG 222
Query: 203 VIIIEGGPQETTKLLSHR--FDYIFYTGSTNIGKIIYASAAKHLTPVTLELGGKSPVYID 260
++ + GP +L+ + + + G+ G+ + S A + L LG +S + +
Sbjct: 223 ILNVVSGPASLVPILASQPGIRKVAFCGAPEEGRALRRSLAGECAELGLALGTESLLLLT 282
Query: 261 DTADLEMTVDRIL 273
DTAD++ V+ ++
Sbjct: 283 DTADVDSAVEGVV 295
>AK124965-1|BAC86008.1| 131|Homo sapiens protein ( Homo sapiens
cDNA FLJ42975 fis, clone BRTHA2002608, weakly similar
to Homo sapiens aldehyde dehydrogenase 1 family, member
A3 (ALDH1A3). ).
Length = 131
Score = 40.7 bits (91), Expect = 0.010
Identities = 14/40 (35%), Positives = 28/40 (70%)
Query: 151 IGAWNYPLALSLLPMAGAIAAGNTVIVKPSEISPASARFI 190
+ WN+PL + + +A A+ GNT+++KP+E +P +A ++
Sbjct: 17 LSQWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYL 56
>AJ567755-1|CAD99005.1| 162|Homo sapiens KI67 Antigen protein.
Length = 162
Score = 33.1 bits (72), Expect = 2.0
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 206 IEGGPQETTKLLSHRFDYIFYTG---STNIGKII-YASAAKHLTPVTLELGGKSPVYIDD 261
+ G PQ+ H+ ++ TG S N+GK + + K LTP L ++P ++D
Sbjct: 17 VSGNPQQQNSPQKHKNKDLYTTGRRESVNLGKSEGFKAGDKTLTPRKLSTRNRTPAKVED 76
Query: 262 TAD 264
AD
Sbjct: 77 AAD 79
>BC112121-1|AAI12122.1| 478|Homo sapiens growth arrest-specific 8
protein.
Length = 478
Score = 31.9 bits (69), Expect = 4.6
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 35 VEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRR 94
VE K + V+ +R + +TR +Q+R + Y++ ++ D L DLRR
Sbjct: 147 VELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDEL--DLRR 204
Query: 95 SKTESLLLEIDYMKNDLKHVL 115
KTE L E++ KN H L
Sbjct: 205 -KTE--LHEVEERKNGQIHTL 222
>BC104785-1|AAI04786.1| 478|Homo sapiens growth arrest-specific 8
protein.
Length = 478
Score = 31.9 bits (69), Expect = 4.6
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 35 VEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRR 94
VE K + V+ +R + +TR +Q+R + Y++ ++ D L DLRR
Sbjct: 147 VELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDEL--DLRR 204
Query: 95 SKTESLLLEIDYMKNDLKHVL 115
KTE L E++ KN H L
Sbjct: 205 -KTE--LHEVEERKNGQIHTL 222
>AF077611-1|AAC27787.1| 193|Homo sapiens interleukin-18 precursor
protein.
Length = 193
Score = 31.9 bits (69), Expect = 4.6
Identities = 16/51 (31%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPLV 405
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL+
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPLL 66
>AF050079-1|AAC69519.1| 478|Homo sapiens growth arrest specific 11
protein.
Length = 478
Score = 31.9 bits (69), Expect = 4.6
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 35 VEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRR 94
VE K + V+ +R + +TR +Q+R + Y++ ++ D L DLRR
Sbjct: 147 VELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDEL--DLRR 204
Query: 95 SKTESLLLEIDYMKNDLKHVL 115
KTE L E++ KN H L
Sbjct: 205 -KTE--LHEVEERKNGQIHTL 222
>AF050078-1|AAC69518.1| 478|Homo sapiens growth arrest specific 11
protein.
Length = 478
Score = 31.9 bits (69), Expect = 4.6
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 35 VEEKSNPKETRQAVQKVRETYNSGVTRCLKWRRKQLRNLYRMYEENANLMLDVLYQDLRR 94
VE K + V+ +R + +TR +Q+R + Y++ ++ D L DLRR
Sbjct: 147 VELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDEL--DLRR 204
Query: 95 SKTESLLLEIDYMKNDLKHVL 115
KTE L E++ KN H L
Sbjct: 205 -KTE--LHEVEERKNGQIHTL 222
>U90434-1|AAB50010.1| 192|Homo sapiens interferon-gamma inducing
factor precursor protein.
Length = 192
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 16 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 64
>D49950-1|BAA08706.1| 193|Homo sapiens interferon-gamma inducing
factor(IGIF) protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>CR542001-1|CAG46798.1| 193|Homo sapiens IL18 protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>CR541973-1|CAG46771.1| 193|Homo sapiens IL18 protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>BC007461-1|AAH07461.1| 193|Homo sapiens interleukin 18
(interferon-gamma-inducing factor) protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>BC007007-1|AAH07007.1| 193|Homo sapiens interleukin 18
(interferon-gamma-inducing factor) protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>AY044641-1|AAK95950.1| 193|Homo sapiens interleukin 18 protein.
Length = 193
Score = 31.5 bits (68), Expect = 6.1
Identities = 16/50 (32%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 356 KFIDLTILTNVDVNDKIMEDEIFGPLLA-ICVVKDINEALKFINERGKPL 404
KFID T+ + +D+ +E + FG L + + V++++N+ + FI++ +PL
Sbjct: 17 KFIDNTLYFIAE-DDENLESDYFGKLESKLSVIRNLNDQVLFIDQGNRPL 65
>AF219939-1|AAF43006.1| 931|Homo sapiens diacylglycerol kinase iota
protein.
Length = 931
Score = 31.5 bits (68), Expect = 6.1
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 281 GQTC-IAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNR 329
G+ C +AP + + Q +QKSKR +DPQ PD RI N+
Sbjct: 547 GEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLNDPQSVPDRLRIRVNK 596
>AF061936-1|AAC62010.1| 1065|Homo sapiens diacylglycerol kinase iota
protein.
Length = 1065
Score = 31.5 bits (68), Expect = 6.1
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 281 GQTC-IAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNR 329
G+ C +AP + + Q +QKSKR +DPQ PD RI N+
Sbjct: 681 GEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLNDPQSVPDRLRIRVNK 730
>AB209167-1|BAD92404.1| 871|Homo sapiens diacylglycerol kinase,
iota variant protein.
Length = 871
Score = 31.5 bits (68), Expect = 6.1
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 281 GQTC-IAPDYVLCTKEIQEKFIQKSKRILKKWFGDDPQKTPDYSRIVNNR 329
G+ C +AP + + Q +QKSKR +DPQ PD RI N+
Sbjct: 518 GEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLNDPQSVPDRLRIRVNK 567
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.137 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 63,953,950
Number of Sequences: 224733
Number of extensions: 2729504
Number of successful extensions: 6390
Number of sequences better than 10.0: 133
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 6067
Number of HSP's gapped (non-prelim): 146
length of query: 440
length of database: 73,234,838
effective HSP length: 92
effective length of query: 348
effective length of database: 52,559,402
effective search space: 18290671896
effective search space used: 18290671896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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