Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001964-TA|BGIBMGA001964-PA|IPR000886|Endoplasmic
reticulum targeting sequence, IPR002018|Carboxylesterase, type B
(1028 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase pro... 144 1e-33
M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein. 144 1e-33
M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein. 144 1e-33
BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase p... 144 1e-33
AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase ... 144 1e-33
L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein. 143 3e-33
AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase ... 143 3e-33
BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein. 142 8e-33
AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo pr... 142 8e-33
BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1 (mon... 141 1e-32
L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein. 140 2e-32
BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein. 139 5e-32
S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholester... 138 9e-32
M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein. 138 9e-32
D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein. 138 9e-32
BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1 (mon... 138 9e-32
AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein. 138 9e-32
AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b p... 138 9e-32
AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a p... 138 9e-32
AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b p... 138 9e-32
AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a p... 138 9e-32
AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase ... 137 2e-31
S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipas... 136 3e-31
X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for ... 136 5e-31
M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase pro... 136 5e-31
M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase prot... 136 5e-31
M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipas... 136 5e-31
BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein. 136 5e-31
BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein. 136 5e-31
AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase (... 136 5e-31
AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lip... 136 5e-31
AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase p... 136 5e-31
AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein. 136 5e-31
BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked ... 133 3e-30
AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester hydro... 133 3e-30
AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein. 133 3e-30
AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein. 133 3e-30
BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein. 132 6e-30
M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase prot... 131 1e-29
BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase, i... 131 1e-29
BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Y... 131 1e-29
BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein. 131 1e-29
AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (Y... 131 1e-29
AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase is... 131 1e-29
AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related acety... 131 1e-29
AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein. 131 1e-29
AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein. 131 1e-29
BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked ... 131 1e-29
BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked ... 131 1e-29
AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein. 131 1e-29
AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein. 131 1e-29
BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein. 130 2e-29
BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7 prot... 130 2e-29
BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein. 130 2e-29
AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5 prot... 130 2e-29
AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens ... 130 2e-29
BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein. 130 2e-29
AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-relate... 129 4e-29
Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein. 126 4e-28
U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein. 126 4e-28
D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precurso... 126 4e-28
BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein. 126 4e-28
BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein. 126 4e-28
BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2 (int... 126 4e-28
AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2 (int... 126 4e-28
AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isof... 126 4e-28
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein. 120 4e-26
M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein. 120 4e-26
AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo pr... 118 8e-26
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein. 118 8e-26
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor... 118 8e-26
X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage serin... 117 2e-25
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein. 116 3e-25
BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for IM... 114 1e-24
AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein. 114 1e-24
AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein. 114 2e-24
BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein. 112 7e-24
BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein. 110 3e-23
AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform pr... 110 3e-23
AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform pr... 110 3e-23
AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein. 110 3e-23
BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein pr... 108 9e-23
AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HN... 108 9e-23
AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HN... 107 2e-22
AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens ... 106 5e-22
M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein. 100 2e-20
BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein. 96 7e-19
AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens ... 96 7e-19
AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens ... 74 3e-12
BC009706-1|AAH09706.1| 150|Homo sapiens CES1 protein protein. 54 2e-06
AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein. 52 8e-06
Z47542-1|CAA87590.1| 368|Homo sapiens SNAP43 protein. 33 6.9
U44754-1|AAC50358.1| 368|Homo sapiens PSE-binding factor PTF ga... 33 6.9
BC019038-1|AAH19038.1| 368|Homo sapiens small nuclear RNA activ... 33 6.9
BC014984-1|AAH14984.1| 368|Homo sapiens small nuclear RNA activ... 33 6.9
>M32391-1|AAA99296.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 144 bits (349), Expect = 1e-33
Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 30/312 (9%)
Query: 17 EGGVIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNA 76
E +I+ T +GKV G+ + + +FL IPY + P+G LRFK PQ W+D+ NA
Sbjct: 29 EDDIIIATKNGKVRGMNLT--VFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNA 86
Query: 77 KKERKQCAQYYVPMRPVDEVGFCGSE----------DCLHLNIHTXXXXXXXXXXXXVIV 126
K C Q P GF GSE DCL+LN+ V++
Sbjct: 87 TKYANSCCQNIDQSFP----GFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNAT---VLI 139
Query: 127 FLYNEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDV 184
++Y F+ ++ Y F + E VI+V++++RVG GF++ G+ PGN G+ D
Sbjct: 140 WIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQ 199
Query: 185 ILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
LAL+W+Q NI FGGNP +TL G+ GAA V + L SP + LF+ AILQSG+ +
Sbjct: 200 QLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPW 259
Query: 245 FFNT--KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVP 302
+ + ++R L +A++ N + I L + +I +E + Y P
Sbjct: 260 AVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVV------PYGTP 313
Query: 303 ILAN-GPVVEHD 313
+ N GP V+ D
Sbjct: 314 LSVNFGPTVDGD 325
Score = 109 bits (263), Expect = 4e-23
Identities = 121/480 (25%), Positives = 212/480 (44%), Gaps = 45/480 (9%)
Query: 543 SEDCLFINIFTPSLKG-SAPVVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRL 600
SEDCL++N++ P+ K +A V+++ Y F+TG + Y F E V+VV++++R+
Sbjct: 117 SEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRV 176
Query: 601 GLLGYLTTEDDV-IPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
G LG+L + PGN GL D L LQW+Q NI +FGG+ V++ G GAA L
Sbjct: 177 GALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHL 236
Query: 660 YSKKAKGLFSAVMIQSGT--TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVE 717
S + LF+ ++QSG+ A+ + + ++ ++ +++ L+ +
Sbjct: 237 LSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKD 296
Query: 718 AGELLRNEIGVLDNDEFENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFN 777
E+L NE V+ + F PT++ + + L E G +L+G N
Sbjct: 297 PQEILLNEAFVV-----PYGTPLSVNFGPTVDGDFLTDMPDILLELGQF-KKTQILVGVN 350
Query: 778 SREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYR-FVNGDKAYKEAAKDILEFYFEDK 836
EG T+ + S I + ++ + F G E K+ + F++ D
Sbjct: 351 KDEG---TAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPG---VSEFGKESILFHYTD- 403
Query: 837 SVHYGNVMEYTVYAGDVLQMYAL---QKAVTKLSAELQSNLYFYMFDFLGEFNENSYHIS 893
V Y GDV+ Y TK +E +N +FY F E+
Sbjct: 404 WVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYF-------EHRSSKL 456
Query: 894 RFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKS 953
+ + HG I E + R R+ Y + ++ L + +V+ W NFAK
Sbjct: 457 PWPEWMGVMHGYEI--EFVFGLPLER-RDNYTKAEEI--------LSRSIVKRWANFAKY 505
Query: 954 RNPTPSKDDTVLNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFLDKYSKM 1013
NP +++++ + ++K E++ LN T+ R+ + +FW +F K +M
Sbjct: 506 GNPNETQNNST-SWPVFKSTEQKYLTLN----TESTRIMTKLRAQQCRFWTSFFPKVLEM 560
>M16541-1|AAA98113.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 144 bits (349), Expect = 1e-33
Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 30/312 (9%)
Query: 17 EGGVIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNA 76
E +I+ T +GKV G+ + + +FL IPY + P+G LRFK PQ W+D+ NA
Sbjct: 29 EDDIIIATKNGKVRGMNLT--VFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNA 86
Query: 77 KKERKQCAQYYVPMRPVDEVGFCGSE----------DCLHLNIHTXXXXXXXXXXXXVIV 126
K C Q P GF GSE DCL+LN+ V++
Sbjct: 87 TKYANSCCQNIDQSFP----GFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNAT---VLI 139
Query: 127 FLYNEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDV 184
++Y F+ ++ Y F + E VI+V++++RVG GF++ G+ PGN G+ D
Sbjct: 140 WIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQ 199
Query: 185 ILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
LAL+W+Q NI FGGNP +TL G+ GAA V + L SP + LF+ AILQSG+ +
Sbjct: 200 QLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPW 259
Query: 245 FFNT--KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVP 302
+ + ++R L +A++ N + I L + +I +E + Y P
Sbjct: 260 AVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVV------PYGTP 313
Query: 303 ILAN-GPVVEHD 313
+ N GP V+ D
Sbjct: 314 LSVNFGPTVDGD 325
Score = 109 bits (263), Expect = 4e-23
Identities = 121/480 (25%), Positives = 212/480 (44%), Gaps = 45/480 (9%)
Query: 543 SEDCLFINIFTPSLKG-SAPVVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRL 600
SEDCL++N++ P+ K +A V+++ Y F+TG + Y F E V+VV++++R+
Sbjct: 117 SEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRV 176
Query: 601 GLLGYLTTEDDV-IPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
G LG+L + PGN GL D L LQW+Q NI +FGG+ V++ G GAA L
Sbjct: 177 GALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHL 236
Query: 660 YSKKAKGLFSAVMIQSGT--TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVE 717
S + LF+ ++QSG+ A+ + + ++ ++ +++ L+ +
Sbjct: 237 LSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKD 296
Query: 718 AGELLRNEIGVLDNDEFENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFN 777
E+L NE V+ + F PT++ + + L E G +L+G N
Sbjct: 297 PQEILLNEAFVV-----PYGTPLSVNFGPTVDGDFLTDMPDILLELGQF-KKTQILVGVN 350
Query: 778 SREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYR-FVNGDKAYKEAAKDILEFYFEDK 836
EG T+ + S I + ++ + F G E K+ + F++ D
Sbjct: 351 KDEG---TAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPG---VSEFGKESILFHYTD- 403
Query: 837 SVHYGNVMEYTVYAGDVLQMYAL---QKAVTKLSAELQSNLYFYMFDFLGEFNENSYHIS 893
V Y GDV+ Y TK +E +N +FY F E+
Sbjct: 404 WVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYF-------EHRSSKL 456
Query: 894 RFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKS 953
+ + HG I E + R R+ Y + ++ L + +V+ W NFAK
Sbjct: 457 PWPEWMGVMHGYEI--EFVFGLPLER-RDNYTKAEEI--------LSRSIVKRWANFAKY 505
Query: 954 RNPTPSKDDTVLNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFLDKYSKM 1013
NP +++++ + ++K E++ LN T+ R+ + +FW +F K +M
Sbjct: 506 GNPNETQNNST-SWPVFKSTEQKYLTLN----TESTRIMTKLRAQQCRFWTSFFPKVLEM 560
>M16474-1|AAA52015.1| 602|Homo sapiens BCHE protein.
Length = 602
Score = 144 bits (349), Expect = 1e-33
Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 30/312 (9%)
Query: 17 EGGVIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNA 76
E +I+ T +GKV G+ + + +FL IPY + P+G LRFK PQ W+D+ NA
Sbjct: 29 EDDIIIATKNGKVRGMNLT--VFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNA 86
Query: 77 KKERKQCAQYYVPMRPVDEVGFCGSE----------DCLHLNIHTXXXXXXXXXXXXVIV 126
K C Q P GF GSE DCL+LN+ V++
Sbjct: 87 TKYANSCCQNIDQSFP----GFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNAT---VLI 139
Query: 127 FLYNEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDV 184
++Y F+ ++ Y F + E VI+V++++RVG GF++ G+ PGN G+ D
Sbjct: 140 WIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQ 199
Query: 185 ILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
LAL+W+Q NI FGGNP +TL G+ GAA V + L SP + LF+ AILQSG+ +
Sbjct: 200 QLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPW 259
Query: 245 FFNT--KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVP 302
+ + ++R L +A++ N + I L + +I +E + Y P
Sbjct: 260 AVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVV------PYGTP 313
Query: 303 ILAN-GPVVEHD 313
+ N GP V+ D
Sbjct: 314 LSVNFGPTVDGD 325
Score = 109 bits (263), Expect = 4e-23
Identities = 121/480 (25%), Positives = 212/480 (44%), Gaps = 45/480 (9%)
Query: 543 SEDCLFINIFTPSLKG-SAPVVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRL 600
SEDCL++N++ P+ K +A V+++ Y F+TG + Y F E V+VV++++R+
Sbjct: 117 SEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRV 176
Query: 601 GLLGYLTTEDDV-IPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
G LG+L + PGN GL D L LQW+Q NI +FGG+ V++ G GAA L
Sbjct: 177 GALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHL 236
Query: 660 YSKKAKGLFSAVMIQSGT--TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVE 717
S + LF+ ++QSG+ A+ + + ++ ++ +++ L+ +
Sbjct: 237 LSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKD 296
Query: 718 AGELLRNEIGVLDNDEFENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFN 777
E+L NE V+ + F PT++ + + L E G +L+G N
Sbjct: 297 PQEILLNEAFVV-----PYGTPLSVNFGPTVDGDFLTDMPDILLELGQF-KKTQILVGVN 350
Query: 778 SREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYR-FVNGDKAYKEAAKDILEFYFEDK 836
EG T+ + S I + ++ + F G E K+ + F++ D
Sbjct: 351 KDEG---TAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPG---VSEFGKESILFHYTD- 403
Query: 837 SVHYGNVMEYTVYAGDVLQMYAL---QKAVTKLSAELQSNLYFYMFDFLGEFNENSYHIS 893
V Y GDV+ Y TK +E +N +FY F E+
Sbjct: 404 WVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYF-------EHRSSKL 456
Query: 894 RFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKS 953
+ + HG I E + R R+ Y + ++ L + +V+ W NFAK
Sbjct: 457 PWPEWMGVMHGYEI--EFVFGLPLER-RDNYTKAEEI--------LSRSIVKRWANFAKY 505
Query: 954 RNPTPSKDDTVLNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFLDKYSKM 1013
NP +++++ + ++K E++ LN T+ R+ + +FW +F K +M
Sbjct: 506 GNPNETQNNST-SWPVFKSTEQKYLTLN----TESTRIMTKLRAQQCRFWTSFFPKVLEM 560
>BC018141-1|AAH18141.1| 602|Homo sapiens butyrylcholinesterase
protein.
Length = 602
Score = 144 bits (349), Expect = 1e-33
Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 30/312 (9%)
Query: 17 EGGVIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNA 76
E +I+ T +GKV G+ + + +FL IPY + P+G LRFK PQ W+D+ NA
Sbjct: 29 EDDIIIATKNGKVRGMNLT--VFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNA 86
Query: 77 KKERKQCAQYYVPMRPVDEVGFCGSE----------DCLHLNIHTXXXXXXXXXXXXVIV 126
K C Q P GF GSE DCL+LN+ V++
Sbjct: 87 TKYANSCCQNIDQSFP----GFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNAT---VLI 139
Query: 127 FLYNEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDV 184
++Y F+ ++ Y F + E VI+V++++RVG GF++ G+ PGN G+ D
Sbjct: 140 WIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQ 199
Query: 185 ILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
LAL+W+Q NI FGGNP +TL G+ GAA V + L SP + LF+ AILQSG+ +
Sbjct: 200 QLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPW 259
Query: 245 FFNT--KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVP 302
+ + ++R L +A++ N + I L + +I +E + Y P
Sbjct: 260 AVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVV------PYGTP 313
Query: 303 ILAN-GPVVEHD 313
+ N GP V+ D
Sbjct: 314 LSVNFGPTVDGD 325
Score = 109 bits (263), Expect = 4e-23
Identities = 121/480 (25%), Positives = 212/480 (44%), Gaps = 45/480 (9%)
Query: 543 SEDCLFINIFTPSLKG-SAPVVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRL 600
SEDCL++N++ P+ K +A V+++ Y F+TG + Y F E V+VV++++R+
Sbjct: 117 SEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRV 176
Query: 601 GLLGYLTTEDDV-IPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
G LG+L + PGN GL D L LQW+Q NI +FGG+ V++ G GAA L
Sbjct: 177 GALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHL 236
Query: 660 YSKKAKGLFSAVMIQSGT--TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVE 717
S + LF+ ++QSG+ A+ + + ++ ++ +++ L+ +
Sbjct: 237 LSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKD 296
Query: 718 AGELLRNEIGVLDNDEFENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFN 777
E+L NE V+ + F PT++ + + L E G +L+G N
Sbjct: 297 PQEILLNEAFVV-----PYGTPLSVNFGPTVDGDFLTDMPDILLELGQF-KKTQILVGVN 350
Query: 778 SREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYR-FVNGDKAYKEAAKDILEFYFEDK 836
EG T+ + S I + ++ + F G E K+ + F++ D
Sbjct: 351 KDEG---TAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPG---VSEFGKESILFHYTD- 403
Query: 837 SVHYGNVMEYTVYAGDVLQMYAL---QKAVTKLSAELQSNLYFYMFDFLGEFNENSYHIS 893
V Y GDV+ Y TK +E +N +FY F E+
Sbjct: 404 WVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYF-------EHRSSKL 456
Query: 894 RFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKS 953
+ + HG I E + R R+ Y + ++ L + +V+ W NFAK
Sbjct: 457 PWPEWMGVMHGYEI--EFVFGLPLER-RDNYTKAEEI--------LSRSIVKRWANFAKY 505
Query: 954 RNPTPSKDDTVLNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFLDKYSKM 1013
NP +++++ + ++K E++ LN T+ R+ + +FW +F K +M
Sbjct: 506 GNPNETQNNST-SWPVFKSTEQKYLTLN----TESTRIMTKLRAQQCRFWTSFFPKVLEM 560
>AB025027-1|BAB85656.1| 565|Homo sapiens brain carboxylesterase
hBr2 protein.
Length = 565
Score = 144 bits (349), Expect = 1e-33
Identities = 132/459 (28%), Positives = 201/459 (43%), Gaps = 40/459 (8%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL +P+ K P+G LRF PQ E W V N
Sbjct: 25 VVDTVQGKVLGKYVSLEGFAQPVAVFLGVPFAKPPLGPLRFAPPQAAEPWNFVKNTTSYP 84
Query: 81 KQCAQYYVPMRPV--------DEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C+Q V + + D + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCSQDAVGGQVLSELFTNRKDNIPLKFSEDCLYLNIYTPADLTKNSRLP-VMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 L-VVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHGRGNWGHLDQLAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKD 252
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A ++ KD
Sbjct: 203 ENIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTAALVKKDMKD 262
Query: 253 RALAIAEVLERKLSNSAQFISELGSIAAPKISESEL------MAIHADDSRKYQ-VPILA 305
A IA K + SA + L ++ E L + + D Y +P +
Sbjct: 263 TAQQIAVFAGCKSTTSAVLVHCLRQKTEDELLEVSLKLKFFTLDLLGDPRESYPFLPTVV 322
Query: 306 NGPVVEHDHPDAVITKRPEDSFLDVEIPIMIGYNTRE---SIEMMERYLRKPQYLTFADR 362
+G V+ P ++ ++ +S +P +IG N +E + MM Y L
Sbjct: 323 DG-VLLPKMPQEILAEKKFNS-----VPYIIGINKQEFGWLLPMMMGYPLSEDKLDQKTA 376
Query: 363 DFLM--MFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYS 420
L+ +PI N+ E + YL + K F+ + D+ F
Sbjct: 377 SSLLWKSYPI---------ANIPEELTPLASEKYLGGTDDPVKKKALFLDMLGDV-VFGV 426
Query: 421 VDYAVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R+ ++ A Y Y F Y S +M+ Q ++ D
Sbjct: 427 PSVTVARHHRDAGAPTYMYEFQYHPSFSSDMKPQTVVGD 465
Score = 124 bits (298), Expect = 2e-27
Identities = 116/424 (27%), Positives = 187/424 (44%), Gaps = 39/424 (9%)
Query: 543 SEDCLFINIFTPS--LKGSA-PVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISH 598
SEDCL++NI+TP+ K S PV+V+ + G G+ TY E VVVVTI +
Sbjct: 113 SEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVG--GASTYDGLALSAHENVVVVTIQY 170
Query: 599 RLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETL 658
RLG+ G+ +T D+ GN G D L L+W+Q+NI +FGG+ V++ G G L
Sbjct: 171 RLGIWGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGESAGGESVSVL 230
Query: 659 LYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEA 718
+ S AK LF + +SG L A + K A + ++ S VL+ L++
Sbjct: 231 VLSPLAKNLFHRAISESGVALTAALVKKDMKDTAQQIAVFAGCKSTTSAVLVHCLRQKTE 290
Query: 719 GELLRNEIGV-LDNDEFENDQHSTFPFAPTIE-----PENPEAVITNLPENGHIVNDVPV 772
ELL + + + D ++PF PT+ P+ P+ ++ N VP
Sbjct: 291 DELLEVSLKLKFFTLDLLGDPRESYPFLPTVVDGVLLPKMPQEILAEKK-----FNSVPY 345
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
+IG N +E L + P L ++++ + ++Y N + A E Y
Sbjct: 346 IIGINKQEFGWLLPMMMGYP-LSEDKLDQKTASSLLWKSYPIANIPEELTPLAS---EKY 401
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ GDV ++ + +VT + YM++F YH
Sbjct: 402 LGGTDDPVKKKALFLDMLGDV--VFGV-PSVTVARHHRDAGAPTYMYEF-------QYHP 451
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
S S K + GDEL + ++ + ++++L K M++LW NFA+
Sbjct: 452 SFSSDMKPQTVVGDHGDELFSVFGAPFLKGGASE--------EEIRLSKMMMKLWANFAR 503
Query: 953 SRNP 956
S NP
Sbjct: 504 SGNP 507
>L07765-1|AAA35711.1| 566|Homo sapiens carboxylesterase protein.
Length = 566
Score = 143 bits (347), Expect = 3e-33
Identities = 132/455 (29%), Positives = 203/455 (44%), Gaps = 31/455 (6%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+GK P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
V++ ++ K PE+ + +P M+G N +E ++ + P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKT 376
Query: 365 LMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDYA 424
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 AMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSVI 431
Query: 425 VRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 466
Score = 109 bits (261), Expect = 7e-23
Identities = 118/473 (24%), Positives = 197/473 (41%), Gaps = 44/473 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSREGLD 783
+ + + + D + P T+ ++ PE + VP ++G N +E
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 784 LTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNV 843
L ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKKK 413
Query: 844 MEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENH 903
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 DLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKTV 463
Query: 904 GATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 IGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 508
>AB025028-1|BAA84996.1| 567|Homo sapiens brain carboxylesterase
hBr3 protein.
Length = 567
Score = 143 bits (347), Expect = 3e-33
Identities = 104/337 (30%), Positives = 160/337 (47%), Gaps = 23/337 (6%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V T GKV G V + FL +P+ K P+G+LRF PQP E W+ V N
Sbjct: 25 VVNTVKGKVLGKYVNLEGFTQPVAFFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C+Q V + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCSQDAVGWQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLP-VMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 L-VVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKD 252
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG + ++ T K
Sbjct: 203 DNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKP 262
Query: 253 RALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVPILANG----P 308
A +A + K + SA + L ++ E+ L +++ +L N P
Sbjct: 263 IAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKL------NLFKLDLLGNPKESYP 316
Query: 309 VVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRE 342
+ V+ K PE+ + +P ++G N +E
Sbjct: 317 FLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQE 353
Score = 116 bits (279), Expect = 4e-25
Identities = 92/299 (30%), Positives = 139/299 (46%), Gaps = 27/299 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGWQVLSELFTNRKENIPLQFSEDCLYLNIY 122
Query: 553 TPS--LKGSA-PVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K S PV+V+ + G G+ TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKNSRLPVMVWIHGGGLVVG--GASTYDGLALSAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI +FGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRN--EI 726
+ +SG +L A K A + +T S V++ L++ ELL ++
Sbjct: 241 HRAISESGVSLTAALITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKL 300
Query: 727 GVLDNDEFENDQHSTFPFAPT-----IEPENPEAVITNLPENGHIVNDVPVLIGFNSRE 780
+ D N + S +PF PT + P+ PE ++ + VP ++G N +E
Sbjct: 301 NLFKLDLLGNPKES-YPFLPTVIDGVVLPKAPEEILAE-----KSFSTVPYIVGINKQE 353
>BC053670-1|AAH53670.1| 568|Homo sapiens CES3 protein protein.
Length = 568
Score = 142 bits (343), Expect = 8e-33
Identities = 121/429 (28%), Positives = 194/429 (45%), Gaps = 28/429 (6%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V+T G+V G +V D FL IP+ + P+G RF AP P + W V +A
Sbjct: 36 VDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPP 95
Query: 82 QCAQYYVPMRPVDEV--G----FCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRI 135
C Q M V G F SEDCL LN+++ V+V+++ I
Sbjct: 96 MCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRP-VMVWVHGGAL-I 153
Query: 136 TYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNI 195
T A+ G DV++VT+ +R+G GF S GD+ PGN G DV+ AL+W+Q NI
Sbjct: 154 TGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENI 213
Query: 196 NKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRAL 255
FGG+ +T+ G G +++ L+ SP A GLF AI QSG + ++ P A
Sbjct: 214 APFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQ 273
Query: 256 AIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHDHP 315
IA L S+ A+ + L + E E + + + + P+ +G V P
Sbjct: 274 KIANTLACSSSSPAEMVQCL------QQKEGEELVL-SKKLKNTIYPLTVDGTVFPKS-P 325
Query: 316 DAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLTFADRDFLMMFPIRVDYH 375
++ ++P S +P ++G N E ++ R + R+ ++ V
Sbjct: 326 KELLKEKPFHS-----VPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPV--- 377
Query: 376 FELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSV-DYAVRRYLNESSA 434
+ +V E + + D YL +K F +M D+ F +V + RYL +S +
Sbjct: 378 -LTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDV--FINVPTVSFSRYLRDSGS 434
Query: 435 QIYYYAFDY 443
+++Y F +
Sbjct: 435 PVFFYEFQH 443
Score = 124 bits (298), Expect = 2e-27
Identities = 92/285 (32%), Positives = 141/285 (49%), Gaps = 25/285 (8%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQF-----SSR-MRNGEEFGISGSEDCLFINIFTPSL--K 557
P P + WEG +A P CLQ SSR + NG++ S SEDCL +N+++P+
Sbjct: 78 PHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPA 137
Query: 558 GSA-PVVVFDYNDNFRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPG 615
GS PV+V+ + TG + +Y G VVVVT+ +RLG+LG+ +T D+ PG
Sbjct: 138 GSGRPVMVWVHGGALITG--AATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPG 195
Query: 616 NNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQS 675
N G D + L+W+Q+NI FGGD + V+V G G +I L+ S A GLF + QS
Sbjct: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255
Query: 676 GTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFE 735
G P A + L + +++ LQ+ E EL+ ++ L N +
Sbjct: 256 GVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSK--KLKNTIY- 312
Query: 736 NDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSRE 780
T+ P++P+ ++ P + VP L+G N+ E
Sbjct: 313 -----PLTVDGTVFPKSPKELLKEKP-----FHSVPFLMGVNNHE 347
>AY358609-1|AAQ88972.1| 571|Homo sapiens carboxylesterase Hlo
protein.
Length = 571
Score = 142 bits (343), Expect = 8e-33
Identities = 121/429 (28%), Positives = 194/429 (45%), Gaps = 28/429 (6%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V+T G+V G +V D FL IP+ + P+G RF AP P + W V +A
Sbjct: 36 VDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPP 95
Query: 82 QCAQYYVPMRPVDEV--G----FCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRI 135
C Q M V G F SEDCL LN+++ V+V+++ I
Sbjct: 96 MCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRP-VMVWVHGGAL-I 153
Query: 136 TYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNI 195
T A+ G DV++VT+ +R+G GF S GD+ PGN G DV+ AL+W+Q NI
Sbjct: 154 TGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENI 213
Query: 196 NKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRAL 255
FGG+ +T+ G G +++ L+ SP A GLF AI QSG + ++ P A
Sbjct: 214 APFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQ 273
Query: 256 AIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHDHP 315
IA L S+ A+ + L + E E + + + + P+ +G V P
Sbjct: 274 KIANTLACSSSSPAEMVQCL------QQKEGEELVL-SKKLKNTIYPLTVDGTVFPKS-P 325
Query: 316 DAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLTFADRDFLMMFPIRVDYH 375
++ ++P S +P ++G N E ++ R + R+ ++ V
Sbjct: 326 KELLKEKPFHS-----VPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPV--- 377
Query: 376 FELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSV-DYAVRRYLNESSA 434
+ +V E + + D YL +K F +M D+ F +V + RYL +S +
Sbjct: 378 -LTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDV--FINVPTVSFSRYLRDSGS 434
Query: 435 QIYYYAFDY 443
+++Y F +
Sbjct: 435 PVFFYEFQH 443
Score = 124 bits (298), Expect = 2e-27
Identities = 92/285 (32%), Positives = 141/285 (49%), Gaps = 25/285 (8%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQF-----SSR-MRNGEEFGISGSEDCLFINIFTPSL--K 557
P P + WEG +A P CLQ SSR + NG++ S SEDCL +N+++P+
Sbjct: 78 PHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPA 137
Query: 558 GSA-PVVVFDYNDNFRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPG 615
GS PV+V+ + TG + +Y G VVVVT+ +RLG+LG+ +T D+ PG
Sbjct: 138 GSGRPVMVWVHGGALITG--AATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPG 195
Query: 616 NNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQS 675
N G D + L+W+Q+NI FGGD + V+V G G +I L+ S A GLF + QS
Sbjct: 196 NQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQS 255
Query: 676 GTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFE 735
G P A + L + +++ LQ+ E EL+ ++ L N +
Sbjct: 256 GVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSK--KLKNTIY- 312
Query: 736 NDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSRE 780
T+ P++P+ ++ P + VP L+G N+ E
Sbjct: 313 -----PLTVDGTVFPKSPKELLKEKP-----FHSVPFLMGVNNHE 347
>BC012418-1|AAH12418.1| 566|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 566
Score = 141 bits (341), Expect = 1e-32
Identities = 131/455 (28%), Positives = 202/455 (44%), Gaps = 31/455 (6%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
V++ ++ K PE+ + +P M+G N +E ++ + P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKT 376
Query: 365 LMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDYA 424
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 AMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSVI 431
Query: 425 VRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 466
Score = 109 bits (261), Expect = 7e-23
Identities = 118/473 (24%), Positives = 197/473 (41%), Gaps = 44/473 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSREGLD 783
+ + + + D + P T+ ++ PE + VP ++G N +E
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 784 LTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNV 843
L ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKKK 413
Query: 844 MEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENH 903
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 DLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKTV 463
Query: 904 GATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 IGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 508
>L07764-1|AAA16036.1| 568|Homo sapiens carboxylesterase protein.
Length = 568
Score = 140 bits (340), Expect = 2e-32
Identities = 133/456 (29%), Positives = 203/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+GK P+G LRF PQP E W+ V NA
Sbjct: 26 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFGKPPLGPLRFTPPQPAEPWSFVKNATSYP 85
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 86 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 144
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 145 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 203
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 204 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 263
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 264 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 321
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 322 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 377
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 378 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 432
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 433 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 468
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 64 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 123
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 124 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 181
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 182 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 241
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 242 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 301
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 302 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 358
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 359 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 414
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 415 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 464
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 465 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 510
>BC084555-1|AAH84555.1| 454|Homo sapiens FLJ37464 protein protein.
Length = 454
Score = 139 bits (336), Expect = 5e-32
Identities = 98/324 (30%), Positives = 157/324 (48%), Gaps = 22/324 (6%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNA--------KKERKQCAQYYVPMRPVDEVG 97
FL +P+ + P+G LRF P+P E W + +A ++ Q A YV R +
Sbjct: 14 FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYK-W 72
Query: 98 FCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVT 157
SEDCL+LN++ ++ F + I AS G D +E V+LV
Sbjct: 73 LRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF--IVGAASSYEGSDLAAREKVVLVF 130
Query: 158 ISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMV 217
+ HR+G FGF+S D GN G+ D + AL+W+Q NI FGG+P +TL GQ GA +
Sbjct: 131 LQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSI 190
Query: 218 DILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGS 277
L+ SP A GLF AI QSGTA +F + P A +A + +++ ++ L +
Sbjct: 191 SGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRA 250
Query: 278 IAAPKIS--ESELMAIHADDSRKYQVPILANGPVVE----HDHPDAVITKRPEDSFLDVE 331
++ K+ +++ + + R + I + PVV+ D P ++T+ S
Sbjct: 251 LSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSS----- 305
Query: 332 IPIMIGYNTRESIEMMERYLRKPQ 355
+P ++G N E ++ + K Q
Sbjct: 306 VPYLLGVNNLEFNWLLPYNITKEQ 329
Score = 127 bits (307), Expect = 2e-28
Identities = 87/297 (29%), Positives = 147/297 (49%), Gaps = 22/297 (7%)
Query: 500 VLKSMPPVPHKGWEGTYEAYVEKPTCLQ------FSSRMRNGEEFG-ISGSEDCLFINIF 552
+L+ PP P + W+G +A P CLQ S + E + + SEDCL++N++
Sbjct: 26 ILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVY 85
Query: 553 TPSLKGS---APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ PV+V+ F G S D E VV+V + HRLG+ G+L+T+
Sbjct: 86 APARAPGDPQLPVMVWFPGGAFIVGAASSYE-GSDLAAREKVVLVFLQHRLGIFGFLSTD 144
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D GN GL D + L+W+Q+NI +FGGD V++ G GA L+ S A GLF
Sbjct: 145 DSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFH 204
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLR--NEIG 727
+ QSGT L ++ P A + + + +++L+ L+ + +++R N++
Sbjct: 205 RAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMR 264
Query: 728 VLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSRE 780
L + + + + +P ++ P++P ++T G V+ VP L+G N+ E
Sbjct: 265 FLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLT----QGK-VSSVPYLLGVNNLE 316
>S73751-1|AAC60631.2| 568|Homo sapiens acyl coenzyme A:cholesterol
acyltransferase protein.
Length = 568
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 26 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 85
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 86 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 144
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 145 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 203
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 204 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 263
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 264 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 321
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 322 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 377
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 378 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 432
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 433 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 468
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 64 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 123
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 124 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 181
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 182 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 241
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 242 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 301
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 302 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 358
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 359 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 414
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 415 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 464
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 465 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 510
>M73499-1|AAA35649.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>D21088-1|BAA04650.1| 567|Homo sapiens carboxylesterase protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>BC110338-1|AAI10339.1| 567|Homo sapiens carboxylesterase 1
(monocyte/macrophage serine esterase 1) protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AF177775-1|AAD53175.1| 567|Homo sapiens egasyn protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AB119998-1|BAC87751.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AB119997-1|BAC87750.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AB119996-1|BAC87749.1| 567|Homo sapiens carboxylesterase HU1b
protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AB119995-1|BAC87748.1| 567|Homo sapiens carboxylesterase HU1a
protein.
Length = 567
Score = 138 bits (334), Expect = 9e-32
Identities = 132/456 (28%), Positives = 202/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AB025026-1|BAA84995.1| 429|Homo sapiens brain carboxylesterase
hBr1 protein.
Length = 429
Score = 137 bits (331), Expect = 2e-31
Identities = 108/338 (31%), Positives = 161/338 (47%), Gaps = 24/338 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C Q + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRE 342
V++ ++ K PE+ + +P M+G N +E
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQE 354
Score = 107 bits (258), Expect = 2e-22
Identities = 92/333 (27%), Positives = 149/333 (44%), Gaps = 24/333 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 63 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFV 815
+ ++ P L Q+++ + ++Y V
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV 389
>S79774-1|AAB35488.2| 742|Homo sapiens bile salt-dependent lipase
protein.
Length = 742
Score = 136 bits (330), Expect = 3e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 26 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 82
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 83 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 137
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 138 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 197
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 198 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRAAISQSGVALSPWVIQKNPLFWA 257
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 258 KKVAEKVGCPVGDAAR 273
Score = 121 bits (291), Expect = 2e-26
Identities = 131/497 (26%), Positives = 206/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 65 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 119
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 120 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 179
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL A + Q
Sbjct: 180 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRAAISQ 239
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + + L E+
Sbjct: 240 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPAAVTVAYKVPLAGLEY 299
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 300 PMLHY--VGFVPVIDEDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 354
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 355 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKIVVDFETDV 411
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 412 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 460
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 461 YVFGKPFATPTGYRP--------QDRTVFKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 509
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 510 PYTTENS--GYLEITKK 524
>X54457-1|CAA38325.1| 745|Homo sapiens protein ( Human mRNA for
bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
Length = 745
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 357
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 358 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 414
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 415 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 463
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 464 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 512
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 513 PYTTENS--GYLEITKK 527
>M94579-1|AAA51973.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 357
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 358 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 414
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 415 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 463
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 464 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 512
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 513 PYTTENS--GYLEITKK 527
>M85201-1|AAA52014.1| 747|Homo sapiens cholesterol esterase
protein.
Length = 747
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 357
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 358 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 414
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 415 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 463
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 464 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 512
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 513 PYTTENS--GYLEITKK 527
>M54994-1|AAA63211.1| 742|Homo sapiens bile salt-activated lipase
protein.
Length = 742
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 26 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 82
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 83 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 137
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 138 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 197
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 198 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 257
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 258 KKVAEKVGCPVGDAAR 273
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 65 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 119
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 120 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 179
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 180 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 239
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 240 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 299
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 300 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 354
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 355 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 411
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 412 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 460
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 461 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 509
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 510 PYTTENS--GYLEITKK 524
>BC042510-1|AAH42510.1| 722|Homo sapiens CEL protein protein.
Length = 722
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 119 bits (287), Expect = 5e-26
Identities = 132/497 (26%), Positives = 205/497 (41%), Gaps = 52/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S + MP +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFAS--IDMPAI 355
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ + + + G + K E + +D S N + V + DV
Sbjct: 356 NKGNKKVTEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 413
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 414 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 462
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 463 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 511
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 512 PYTTENS--GYLEITKK 526
>BC032555-1|AAH32555.1| 823|Homo sapiens neuroligin 1 protein.
Length = 823
Score = 136 bits (328), Expect = 5e-31
Identities = 120/399 (30%), Positives = 186/399 (46%), Gaps = 46/399 (11%)
Query: 21 IVETNSGKVEGLEVKSIIKDE---KFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ G +K + +E FL +PY P G RF+ P+P W+D+ NA
Sbjct: 54 LVATNFGKIRG--IKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNAT 111
Query: 78 KERKQCAQYYVP------MRPV------DEVGFC---GSEDCLHLNIH--TXXXXXXXXX 120
+ C Q + M PV D V SEDCL+LNI+ T
Sbjct: 112 QFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGG 171
Query: 121 XXXVIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V+V+++ Y T N G +VI++T+++R+G GF+S GD GN
Sbjct: 172 PKPVMVYIHGGSYMEGTGNLYD--GSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNY 229
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILL--H-------SPKAKGLF 230
G+ D+I AL+W NI FGG+P +IT+ G G + V++L H S KGLF
Sbjct: 230 GLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLF 289
Query: 231 SGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMA 290
AI QSGTA SS + +P A +A + +S++ + + L K EL+
Sbjct: 290 QRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECL-----QKKPYKELVD 344
Query: 291 IHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMER 349
+R + +A GPV++ D PD + FL+ + IM+G N E ++ +E
Sbjct: 345 QDIQPARYH----IAFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVEN 398
Query: 350 YLRKPQYLTFADRDFLMMFPIRVDYHFELNTNVYYEAIQ 388
+ ++ +D DF + + Y + +V E I+
Sbjct: 399 IVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIK 437
Score = 121 bits (291), Expect = 2e-26
Identities = 133/492 (27%), Positives = 205/492 (41%), Gaps = 66/492 (13%)
Query: 543 SEDCLFINIFTPSLK------GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEG-VVVVT 595
SEDCL++NI+ P+ G PV+V+ + ++ G G+L Y G V+V+T
Sbjct: 150 SEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEG-TGNL-YDGSVLASYGNVIVIT 207
Query: 596 ISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIA 655
+++RLG+LG+L+T D GN GL D + L+W +NI FGGD R++V G+ G +
Sbjct: 208 VNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCV 267
Query: 656 ETLL---------YSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDS 706
L +S KGLF + QSGT L + P A + D+
Sbjct: 268 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDT 327
Query: 707 EVLLEGLQKVEAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPE 762
L+E LQK EL +D D H F P I+ P++P+ L E
Sbjct: 328 VELVECLQKKPYKEL-------VDQDIQPARYH--IAFGPVIDGDVIPDDPQI----LME 374
Query: 763 NGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYK 822
G +N +++G N EGL + + +S + V + Y + G K
Sbjct: 375 QGEFLN-YDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEG----K 429
Query: 823 EAAKDILEFYFED-KSVHYGNVMEYTVYA-GDVLQMYALQKAVTKLSAELQSNLYFYMFD 880
+ ++ ++F + D H T+ A Q A A L + S YFY F
Sbjct: 430 DVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAF- 488
Query: 881 FLGEFNENSYHISRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLL 940
YH + + A GDE+ Y+ I T ++ DV L
Sbjct: 489 ---------YHHCQTDQVPAWADAAH-GDEVPYVLGIPMIGPT--ELFPCNFSKNDVMLS 536
Query: 941 KKMVRLWTNFAKSRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRM 991
++ WTNFAK+ +P P DT + W ++ + YLHI KPR+
Sbjct: 537 AVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQL--YLHIGLKPRV 594
Query: 992 DVNPLGDRAKFW 1003
+ ++ W
Sbjct: 595 KEHYRANKVNLW 606
>AL162417-8|CAI13412.1| 756|Homo sapiens carboxyl ester lipase
(bile salt-stimulated lipase) protein.
Length = 756
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 357
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 358 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 414
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 415 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 463
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 464 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 512
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 513 PYTTENS--GYLEITKK 527
>AF081673-1|AAC71012.1| 612|Homo sapiens bile salt-dependent lipase
oncofetal isoform protein.
Length = 612
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 6 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 62
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 63 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 117
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 118 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 177
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 178 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 237
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 238 KKVAEKVGCPVGDAAR 253
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 45 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 99
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 100 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 159
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 160 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 219
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 220 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 279
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 280 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 334
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 335 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 391
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 392 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 440
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 441 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 489
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 490 PYTTENS--GYLEITKK 504
>AF072711-1|AAC26514.1| 745|Homo sapiens carboxyl ester lipase
protein.
Length = 745
Score = 136 bits (328), Expect = 5e-31
Identities = 88/256 (34%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERK 81
V T G VEG+ K + + F IP+ AP AL + PQPH GW L AK +K
Sbjct: 29 VYTEGGFVEGVNKKLGLLGDSVDIFKGIPFA-APTKAL--ENPQPHPGWQGTLKAKNFKK 85
Query: 82 QCAQYYVPMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASK 141
+C Q + + G EDCL+LNI V++++Y F +
Sbjct: 86 RCLQ-----ATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGA 140
Query: 142 EY-------GPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSN 194
+ G + + +VI+VT ++RVG GF+S GD LPGN G++D +A+ W++ N
Sbjct: 141 NFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRN 200
Query: 195 INKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRA 254
I FGG+P ITL G+ G A V + SP KGL AI QSG A S P A
Sbjct: 201 IAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWA 260
Query: 255 LAIAEVLERKLSNSAQ 270
+AE + + ++A+
Sbjct: 261 KKVAEKVGCPVGDAAR 276
Score = 118 bits (284), Expect = 1e-25
Identities = 131/497 (26%), Positives = 205/497 (41%), Gaps = 51/497 (10%)
Query: 506 PVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTPS----LKGSAP 561
P PH GW+GT +A K CLQ + + G EDCL++NI+ P + P
Sbjct: 68 PQPHPGWQGTLKAKNFKKRCLQATITQDS-----TYGDEDCLYLNIWVPQGRKQVSRDLP 122
Query: 562 VVVFDYNDNFRTG-------FNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIP 614
V+++ Y F G N L + V+VVT ++R+G LG+L+T D +P
Sbjct: 123 VMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLP 182
Query: 615 GNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQ 674
GN GLRD + + W++ NI +FGGD + +++ G G A S KGL + Q
Sbjct: 183 GNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQ 242
Query: 675 SGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEF 734
SG L + P A + + D+ + + L+ + L L E+
Sbjct: 243 SGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEY 302
Query: 735 ENDQHSTFPFAPTIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ F P I+ + A NL N D+ + G N+ +G S +
Sbjct: 303 PMLHY--VGFVPVIDGDFIPADPINLYAN---AADIDYIAGTNNMDGHIFASIDMPAINK 357
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTV-YAGDV 853
+ ++ E + + + G + K E + +D S N + V + DV
Sbjct: 358 GNKKVTEEDF-YKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQE--NKKKTVVDFETDV 414
Query: 854 LQMYALQKAVTKLSAELQS-NLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELC 912
L + + A+ + A +S Y Y+F H SR Y + GA D++
Sbjct: 415 LFLVPTEIALAQHRANAKSAKTYAYLFS----------HPSRMPVY-PKWVGADHADDIQ 463
Query: 913 YLHLCNRIRNT-YKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPTPSKDDTVLNGLIWK 971
Y+ T Y+ QD + K M+ WTNFAK+ +P D V W+
Sbjct: 464 YVFGKPFATPTGYRP--------QDRTVSKAMIAYWTNFAKTGDPNMG-DSAVPTH--WE 512
Query: 972 PVEKEANVLNYLHITKK 988
P E + YL ITKK
Sbjct: 513 PYTTENS--GYLEITKK 527
>AB028993-1|BAA83022.2| 826|Homo sapiens KIAA1070 protein protein.
Length = 826
Score = 136 bits (328), Expect = 5e-31
Identities = 120/399 (30%), Positives = 186/399 (46%), Gaps = 46/399 (11%)
Query: 21 IVETNSGKVEGLEVKSIIKDE---KFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ G +K + +E FL +PY P G RF+ P+P W+D+ NA
Sbjct: 57 LVATNFGKIRG--IKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNAT 114
Query: 78 KERKQCAQYYVP------MRPV------DEVGFC---GSEDCLHLNIH--TXXXXXXXXX 120
+ C Q + M PV D V SEDCL+LNI+ T
Sbjct: 115 QFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGG 174
Query: 121 XXXVIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V+V+++ Y T N G +VI++T+++R+G GF+S GD GN
Sbjct: 175 PKPVMVYIHGGSYMEGTGNLYD--GSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNY 232
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILL--H-------SPKAKGLF 230
G+ D+I AL+W NI FGG+P +IT+ G G + V++L H S KGLF
Sbjct: 233 GLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLF 292
Query: 231 SGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMA 290
AI QSGTA SS + +P A +A + +S++ + + L K EL+
Sbjct: 293 QRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECL-----QKKPYKELVD 347
Query: 291 IHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMER 349
+R + +A GPV++ D PD + FL+ + IM+G N E ++ +E
Sbjct: 348 QDIQPARYH----IAFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVEN 401
Query: 350 YLRKPQYLTFADRDFLMMFPIRVDYHFELNTNVYYEAIQ 388
+ ++ +D DF + + Y + +V E I+
Sbjct: 402 IVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIK 440
Score = 121 bits (291), Expect = 2e-26
Identities = 133/492 (27%), Positives = 205/492 (41%), Gaps = 66/492 (13%)
Query: 543 SEDCLFINIFTPSLK------GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEG-VVVVT 595
SEDCL++NI+ P+ G PV+V+ + ++ G G+L Y G V+V+T
Sbjct: 153 SEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEG-TGNL-YDGSVLASYGNVIVIT 210
Query: 596 ISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIA 655
+++RLG+LG+L+T D GN GL D + L+W +NI FGGD R++V G+ G +
Sbjct: 211 VNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCV 270
Query: 656 ETLL---------YSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDS 706
L +S KGLF + QSGT L + P A + D+
Sbjct: 271 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDT 330
Query: 707 EVLLEGLQKVEAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPE 762
L+E LQK EL +D D H F P I+ P++P+ L E
Sbjct: 331 VELVECLQKKPYKEL-------VDQDIQPARYH--IAFGPVIDGDVIPDDPQI----LME 377
Query: 763 NGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYK 822
G +N +++G N EGL + + +S + V + Y + G K
Sbjct: 378 QGEFLN-YDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEG----K 432
Query: 823 EAAKDILEFYFED-KSVHYGNVMEYTVYA-GDVLQMYALQKAVTKLSAELQSNLYFYMFD 880
+ ++ ++F + D H T+ A Q A A L + S YFY F
Sbjct: 433 DVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAF- 491
Query: 881 FLGEFNENSYHISRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLL 940
YH + + A GDE+ Y+ I T ++ DV L
Sbjct: 492 ---------YHHCQTDQVPAWADAAH-GDEVPYVLGIPMIGPT--ELFPCNFSKNDVMLS 539
Query: 941 KKMVRLWTNFAKSRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRM 991
++ WTNFAK+ +P P DT + W ++ + YLHI KPR+
Sbjct: 540 AVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQL--YLHIGLKPRV 597
Query: 992 DVNPLGDRAKFW 1003
+ ++ W
Sbjct: 598 KEHYRANKVNLW 609
>BC034018-1|AAH34018.1| 816|Homo sapiens neuroligin 4, X-linked
protein.
Length = 816
Score = 133 bits (322), Expect = 3e-30
Identities = 105/366 (28%), Positives = 171/366 (46%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ GL I+ + Y L +PY P G RF+ P+P WT + N
Sbjct: 47 VVNTNYGKIRGLRTPLPNEILGPVEQY--LGVPYASPPTGERRFQPPEPPSSWTGIRNTT 104
Query: 78 KERKQCAQYYVPMRPVDE---VGFCGS------------EDCLHLNIH--TXXXXXXXXX 120
+ C Q+ + + + F + EDCL+LNI+ T
Sbjct: 105 QFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNS 164
Query: 121 XXXVIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V+V+++ Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 165 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 222
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 223 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 282
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 283 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI------TPATY 336
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 337 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 391
Query: 359 FADRDF 364
D DF
Sbjct: 392 PNDFDF 397
Score = 125 bits (302), Expect = 7e-28
Identities = 123/480 (25%), Positives = 201/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTPS------LKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P+ PV+V+ + ++ G G++ V+V+TI
Sbjct: 143 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 201
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNK 321
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 322 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 367
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 368 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 427
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 428 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 475
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 476 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 532
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 533 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
>AY268104-1|AAP20868.1| 567|Homo sapiens cholesteryl ester
hydrolase protein.
Length = 567
Score = 133 bits (322), Expect = 3e-30
Identities = 130/456 (28%), Positives = 201/456 (44%), Gaps = 32/456 (7%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LR PQP E W+ V NA
Sbjct: 25 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRSTPPQPAEPWSFVKNATSYP 84
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEY 132
C + + + E + SEDCL+LNI+T V+V+++
Sbjct: 85 PMCTRDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT-PADLTKKNRLPVMVWIHGGG 143
Query: 133 FRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQ 192
+ AS G E+V++VTI +R+G +GF S GD+ GN G D + AL+W+Q
Sbjct: 144 LMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQ 202
Query: 193 SNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNT-KPK 251
NI FGGNP +T+ G+ G V +L+ SP AK LF AI +SG A +S+ K
Sbjct: 203 DNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVK 262
Query: 252 DRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL----MAIHADDSRKYQVPILANG 307
A IA K + SA + L ++ E+ L +++ + P+L G
Sbjct: 263 PLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLL--G 320
Query: 308 PVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESIEMMERYLRK-PQYLTFADRD 363
V++ ++ K PE+ + +P M+G N +E ++ L P D+
Sbjct: 321 TVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
Query: 364 FLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDY 423
M + Y + E I E + YL + K F+ + D+ F
Sbjct: 377 TAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV-MFGVPSV 431
Query: 424 AVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 432 IVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467
Score = 109 bits (263), Expect = 4e-23
Identities = 118/474 (24%), Positives = 199/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+S PP P + W A P C + S N +E + SEDCL++NI+
Sbjct: 63 LRSTPPQPAEPWSFVKNATSYPPMCTRDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 122
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 123 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 357
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 358 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 413
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 414 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 463
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 464 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 509
>AF376803-1|AAM46112.1| 816|Homo sapiens neuroligin X protein.
Length = 816
Score = 133 bits (322), Expect = 3e-30
Identities = 105/366 (28%), Positives = 171/366 (46%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ GL I+ + Y L +PY P G RF+ P+P WT + N
Sbjct: 47 VVNTNYGKIRGLRTPLPNEILGPVEQY--LGVPYASPPTGERRFQPPEPPSSWTGIRNTT 104
Query: 78 KERKQCAQYYVPMRPVDE---VGFCGS------------EDCLHLNIH--TXXXXXXXXX 120
+ C Q+ + + + F + EDCL+LNI+ T
Sbjct: 105 QFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNS 164
Query: 121 XXXVIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V+V+++ Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 165 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 222
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 223 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 282
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 283 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI------TPATY 336
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 337 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 391
Query: 359 FADRDF 364
D DF
Sbjct: 392 PNDFDF 397
Score = 125 bits (302), Expect = 7e-28
Identities = 123/480 (25%), Positives = 201/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTPS------LKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P+ PV+V+ + ++ G G++ V+V+TI
Sbjct: 143 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 201
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNK 321
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 322 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 367
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 368 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 427
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 428 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 475
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 476 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 532
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 533 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
>AB033086-1|BAA86574.1| 817|Homo sapiens KIAA1260 protein protein.
Length = 817
Score = 133 bits (322), Expect = 3e-30
Identities = 105/366 (28%), Positives = 171/366 (46%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ GL I+ + Y L +PY P G RF+ P+P WT + N
Sbjct: 48 VVNTNYGKIRGLRTPLPNEILGPVEQY--LGVPYASPPTGERRFQPPEPPSSWTGIRNTT 105
Query: 78 KERKQCAQYYVPMRPVDE---VGFCGS------------EDCLHLNIH--TXXXXXXXXX 120
+ C Q+ + + + F + EDCL+LNI+ T
Sbjct: 106 QFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNS 165
Query: 121 XXXVIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V+V+++ Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 166 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 223
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 224 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 283
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 284 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI------TPATY 337
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 338 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 392
Query: 359 FADRDF 364
D DF
Sbjct: 393 PNDFDF 398
Score = 125 bits (302), Expect = 7e-28
Identities = 123/480 (25%), Positives = 201/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTPS------LKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P+ PV+V+ + ++ G G++ V+V+TI
Sbjct: 144 NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 202
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 203 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 262
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 263 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNK 322
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 323 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 368
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 369 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 428
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 429 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 476
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 477 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 533
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 534 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 591
>BC094752-1|AAH94752.1| 640|Homo sapiens ACHE protein protein.
Length = 640
Score = 132 bits (319), Expect = 6e-30
Identities = 82/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T VIV++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VIVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (263), Expect = 4e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVIVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>M55040-1|AAA68151.1| 614|Homo sapiens acetylcholinesterase
protein.
Length = 614
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>BC105062-1|AAI05063.1| 617|Homo sapiens acetylcholinesterase,
isoform E4-E5 precursor protein.
Length = 617
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>BC105060-1|AAI05061.1| 617|Homo sapiens acetylcholinesterase (Yt
blood group) protein.
Length = 617
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>BC036813-1|AAH36813.1| 546|Homo sapiens ACHE protein protein.
Length = 546
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>AY750146-1|AAU43801.1| 617|Homo sapiens acetylcholinesterase (YT
blood group) protein.
Length = 617
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>AK223443-1|BAD97163.1| 614|Homo sapiens acetylcholinesterase
isoform E4-E6 precursor variant protein.
Length = 614
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>AF334270-1|AAO32948.1| 526|Homo sapiens apoptosis-related
acetylcholinesterase protein.
Length = 526
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>AC011895-2|AAP22364.1| 617|Homo sapiens unknown protein.
Length = 617
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>AC011895-1|AAP22365.1| 614|Homo sapiens unknown protein.
Length = 614
Score = 131 bits (317), Expect = 1e-29
Identities = 81/231 (35%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 20 VIVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKE 79
++V G++ G+ +K+ +FL IP+ + P+G RF P+P + W+ V++A
Sbjct: 39 LLVTVRGGRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTF 96
Query: 80 RKQCAQYYVPMRPVDEVGFCG----------SEDCLHLNIHTXXXXXXXXXXXXVIVFLY 129
+ C QY + P GF G SEDCL+LN+ T V+V++Y
Sbjct: 97 QSVCYQYVDTLYP----GFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTP--VLVWIY 150
Query: 130 NEYFRITYNASKEYGPDFFMK-EDVILVTISHRVGTFGFVSF-GDDLLPGNSGVKDVILA 187
F ++ Y F ++ E +LV++++RVG FGF++ G PGN G+ D LA
Sbjct: 151 GGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLA 210
Query: 188 LKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSG 238
L+W+Q N+ FGG+P +TL G+ GAA V + L SP ++GLF A+LQSG
Sbjct: 211 LQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSG 261
Score = 109 bits (261), Expect = 7e-23
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGEEF------GISGSEDCLFINIFTPSLK 557
+PP P + W G +A + C Q+ + G E SEDCL++N++TP +
Sbjct: 79 LPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPR 138
Query: 558 GSAP--VVVFDYNDNFRTGFNGSLTYAPDFFVE-EGVVVVTISHRLGLLGYLTTEDD-VI 613
++P V+V+ Y F +G + Y F V+ E V+V++++R+G G+L
Sbjct: 139 PTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREA 198
Query: 614 PGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMI 673
PGN GL D L LQW+Q+N+ +FGGD + V++ G GAA L S ++GLF ++
Sbjct: 199 PGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVL 258
Query: 674 QSG 676
QSG
Sbjct: 259 QSG 261
>BC113551-1|AAI13552.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 131 bits (316), Expect = 1e-29
Identities = 105/366 (28%), Positives = 168/366 (45%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK++GL I+ + Y L +PY P G RF+ P+ WT + NA
Sbjct: 47 VVNTNYGKIQGLRTPLPSEILGPVEQY--LGVPYASPPTGERRFQPPESPSSWTGIRNAT 104
Query: 78 KERKQCAQYYVP---MRPVDEVGFCGS------------EDCLHLNIHTXXXXXXXXXXX 122
+ C Q+ + + + F S EDCL+LNI+
Sbjct: 105 QFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNS 164
Query: 123 XVIVFLY---NEYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V +Y Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 165 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 222
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 223 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 282
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 283 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI------TPATY 336
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 337 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 391
Query: 359 FADRDF 364
D DF
Sbjct: 392 PNDFDF 397
Score = 125 bits (301), Expect = 9e-28
Identities = 123/480 (25%), Positives = 200/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTP------SLKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P PV+V+ + ++ G G++ V+V+TI
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 201
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNK 321
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 322 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 367
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 368 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 427
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 428 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 475
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 476 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 532
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 533 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
>BC113525-1|AAI13526.1| 816|Homo sapiens neuroligin 4, Y-linked
protein.
Length = 816
Score = 131 bits (316), Expect = 1e-29
Identities = 105/366 (28%), Positives = 168/366 (45%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK++GL I+ + Y L +PY P G RF+ P+ WT + NA
Sbjct: 47 VVNTNYGKIQGLRTPLPSEILGPVEQY--LGVPYASPPTGERRFQPPESPSSWTGIRNAT 104
Query: 78 KERKQCAQYYVP---MRPVDEVGFCGS------------EDCLHLNIHTXXXXXXXXXXX 122
+ C Q+ + + + F S EDCL+LNI+
Sbjct: 105 QFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNS 164
Query: 123 XVIVFLY---NEYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V +Y Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 165 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 222
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 223 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 282
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 283 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI------TPATY 336
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 337 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 391
Query: 359 FADRDF 364
D DF
Sbjct: 392 PNDFDF 397
Score = 125 bits (301), Expect = 9e-28
Identities = 123/480 (25%), Positives = 200/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTP------SLKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P PV+V+ + ++ G G++ V+V+TI
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 201
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNK 321
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 322 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 367
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 368 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 427
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 428 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 475
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 476 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 532
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 533 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
>AF376804-1|AAM46113.1| 816|Homo sapiens neuroligin Y protein.
Length = 816
Score = 131 bits (316), Expect = 1e-29
Identities = 105/366 (28%), Positives = 168/366 (45%), Gaps = 37/366 (10%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK++GL I+ + Y L +PY P G RF+ P+ WT + NA
Sbjct: 47 VVNTNYGKIQGLRTPLPSEILGPVEQY--LGVPYASPPTGERRFQPPESPSSWTGIRNAT 104
Query: 78 KERKQCAQYYVP---MRPVDEVGFCGS------------EDCLHLNIHTXXXXXXXXXXX 122
+ C Q+ + + + F S EDCL+LNI+
Sbjct: 105 QFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNS 164
Query: 123 XVIVFLY---NEYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNS 179
V +Y Y T N G +VI++TI++R+G GF+S GD GN
Sbjct: 165 KKPVMVYIHGGSYMEGTGNMID--GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNY 222
Query: 180 GVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGT 239
G+ D I AL+WI+ N+ FGG+P ++T+ G GA+ V +L S ++GLF AI+QSGT
Sbjct: 223 GLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGT 282
Query: 240 AYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKY 299
A SS N +P +A+ + + ++ + L + ++ + + Y
Sbjct: 283 ALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI------TPATY 336
Query: 300 QVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLT 358
+ A GPV++ D PD + FL+ + IM+G N E ++ ++ + +T
Sbjct: 337 HI---AFGPVIDGDVIPDDPQILMEQGEFLNYD--IMLGVNQGEGLKFVDGIVDNEDGVT 391
Query: 359 FADRDF 364
D DF
Sbjct: 392 PNDFDF 397
Score = 125 bits (301), Expect = 9e-28
Identities = 123/480 (25%), Positives = 200/480 (41%), Gaps = 51/480 (10%)
Query: 543 SEDCLFINIFTP------SLKGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTI 596
+EDCL++NI+ P PV+V+ + ++ G G++ V+V+TI
Sbjct: 143 NEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITI 201
Query: 597 SHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAE 656
++RLG+LG+L+T D GN GL D + L+WI++N+ +FGGD RV++ G+ GA+
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 657 TLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKV 716
L S ++GLF +IQSGT L + P + D+ ++E L+
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNK 321
Query: 717 EAGELLRNEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPV 772
EL++ I F P I+ P++P+ L E G +N +
Sbjct: 322 NYKELIQQTI---------TPATYHIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDI 367
Query: 773 LIGFNSREGLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFY 832
++G N EGL + V+ + V + Y + G +E K + +
Sbjct: 368 MLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDW 427
Query: 833 FEDKSVHYGNVMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHI 892
+ ++ ++ Q A A L A+ S YFY F YH
Sbjct: 428 ADKENPETRRKTLVALFTDH--QWVAPAVATADLHAQYGSPTYFYAF----------YHH 475
Query: 893 SRFSRYKTENHGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAK 952
+ S K + GDE+ Y+ I T ++ DV L ++ WTNFAK
Sbjct: 476 CQ-SEMKPSWADSAHGDEVPYVFGIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAK 532
Query: 953 SRNPT-PSKDDTV--------LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ +P P DT + W + + YLHI KPR+ + + FW
Sbjct: 533 TGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
>AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein.
Length = 835
Score = 131 bits (316), Expect = 1e-29
Identities = 125/459 (27%), Positives = 197/459 (42%), Gaps = 45/459 (9%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G PV++F + ++ G G++ V+V T+++RLG+LG+L+T D GN
Sbjct: 175 GKKPVMLFLHGGSYMEG-TGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNY 233
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R+++ G+ GA+ L+ S ++GLF + QSGT
Sbjct: 234 GLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGT 293
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
+ + P + + +DS +E L++ + EL +D D
Sbjct: 294 AISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL-------VDQDVQPAR 346
Query: 738 QHSTF-PFAP-TIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLV 795
H F P + P++PE L + G +N +LIG N EGL V
Sbjct: 347 YHIAFGPVVDGDVVPDDPEI----LMQQGEFLN-YDMLIGVNQGEGLKFVEDSAESEDGV 401
Query: 796 SHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFED-KSVHYGNVMEYTVYA-GDV 853
S + V + Y + G K+ ++ ++F + D G + T+ A
Sbjct: 402 SASAFDFTVSNFVDNLYGYPEG----KDVLRETIKFMYTDWADRDNGEMRRKTLLALFTD 457
Query: 854 LQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELCY 913
Q A A KL A+ QS +YFY F YH + + + E A GDEL Y
Sbjct: 458 HQWVAPAVATAKLHADYQSPVYFYTF----------YHHCQ-AEGRPEWADAAHGDELPY 506
Query: 914 LHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV-------- 964
+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 507 VFGVPMVGAT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNR 564
Query: 965 LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
++W + YLHI KPR+ N ++ FW
Sbjct: 565 FEEVVWSKFNSKEK--QYLHIGLKPRVRDNYRANKVAFW 601
Score = 116 bits (278), Expect = 6e-25
Identities = 124/457 (27%), Positives = 201/457 (43%), Gaps = 52/457 (11%)
Query: 21 IVETNSGKVEGL--EVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
+V T G+V G+ E+ + I FL +PY P+GA RF+ P+ W V NA
Sbjct: 43 VVNTAYGRVRGVRRELNNEILGP-VVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
Query: 79 ERKQCAQYY---VP--MRPV---DEVGFCG------SEDCLHLNIHTXXXXXXXXXXXX- 123
C Q +P M PV D + SEDCL+LN++
Sbjct: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161
Query: 124 -----------------VIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTF 165
V++FL+ Y T N G +VI+ T+++R+G
Sbjct: 162 ATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFD--GSVLAAYGNVIVATLNYRLGVL 219
Query: 166 GFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPK 225
GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G GA+ V++L+ S
Sbjct: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
Query: 226 AKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISE 285
++GLF AI QSGTA SS N +P L +L K+ + +E K S
Sbjct: 280 SEGLFQKAIAQSGTAISSWSVNYQP----LKYTRLLAAKVGCDREDSAEAVECLRRKPSR 335
Query: 286 SELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESI 344
EL+ +R + +A GPVV+ D PD + FL+ + ++IG N E +
Sbjct: 336 -ELVDQDVQPARYH----IAFGPVVDGDVVPDDPEILMQQGEFLNYD--MLIGVNQGEGL 388
Query: 345 EMMERYLRKPQYLTFADRDFLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISK 404
+ +E ++ + DF + + Y + +V E I+ + + + ++ +
Sbjct: 389 KFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRR 448
Query: 405 PGEFMTYMTDINTFYSVDYAVRRYLNESSAQIYYYAF 441
+ TD + + + A + + + +Y+Y F
Sbjct: 449 K-TLLALFTD-HQWVAPAVATAKLHADYQSPVYFYTF 483
>BC117126-1|AAI17127.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 130 bits (315), Expect = 2e-29
Identities = 80/223 (35%), Positives = 111/223 (49%), Gaps = 8/223 (3%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T G ++G +V + FL +P+ P+G+LRF PQP W ++ A C
Sbjct: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
Query: 84 AQYYV------PMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITY 137
Q M V F SEDCL+LNI+ V+V+ F+ T
Sbjct: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TG 152
Query: 138 NASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINK 197
+AS G EDV++V + +R+G FGF + D PGN KD + AL W+Q NI
Sbjct: 153 SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEF 212
Query: 198 FGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGG+P +T+ G+ GA V L+ SP AKGLF AI++SG A
Sbjct: 213 FGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVA 255
Score = 109 bits (261), Expect = 7e-23
Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGE--------EFGISGSEDCLFINIF 552
L+ P P W+ EA CLQ S + + +FG+S EDCL++NI+
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVS--EDCLYLNIY 127
Query: 553 TPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ + PV+V+ F+TG + S+ E V+VV + +RLG+ G+ TT
Sbjct: 128 APAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTW 186
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D PGN +D + L W+Q NI+ FGGD S V++ G GA +L+ S AKGLF
Sbjct: 187 DQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFH 246
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLLEGLQKVEAGELL 722
+++SG + Y K+ + V DSE LL L+ + ELL
Sbjct: 247 KAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELL 301
>BC069548-1|AAH69548.1| 525|Homo sapiens carboxylesterase 7
protein.
Length = 525
Score = 130 bits (315), Expect = 2e-29
Identities = 80/223 (35%), Positives = 111/223 (49%), Gaps = 8/223 (3%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T G ++G +V + FL +P+ P+G+LRF PQP W ++ A C
Sbjct: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
Query: 84 AQYYV------PMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITY 137
Q M V F SEDCL+LNI+ V+V+ F+ T
Sbjct: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TG 152
Query: 138 NASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINK 197
+AS G EDV++V + +R+G FGF + D PGN KD + AL W+Q NI
Sbjct: 153 SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEF 212
Query: 198 FGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGG+P +T+ G+ GA V L+ SP AKGLF AI++SG A
Sbjct: 213 FGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVA 255
Score = 109 bits (261), Expect = 7e-23
Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGE--------EFGISGSEDCLFINIF 552
L+ P P W+ EA CLQ S + + +FG+S EDCL++NI+
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVS--EDCLYLNIY 127
Query: 553 TPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ + PV+V+ F+TG + S+ E V+VV + +RLG+ G+ TT
Sbjct: 128 APAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTW 186
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D PGN +D + L W+Q NI+ FGGD S V++ G GA +L+ S AKGLF
Sbjct: 187 DQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFH 246
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLLEGLQKVEAGELL 722
+++SG + Y K+ + V DSE LL L+ + ELL
Sbjct: 247 KAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELL 301
>BC069501-1|AAH69501.1| 575|Homo sapiens CES7 protein protein.
Length = 575
Score = 130 bits (315), Expect = 2e-29
Identities = 80/223 (35%), Positives = 111/223 (49%), Gaps = 8/223 (3%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T G ++G +V + FL +P+ P+G+LRF PQP W ++ A C
Sbjct: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
Query: 84 AQYYV------PMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITY 137
Q M V F SEDCL+LNI+ V+V+ F+ T
Sbjct: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TG 152
Query: 138 NASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINK 197
+AS G EDV++V + +R+G FGF + D PGN KD + AL W+Q NI
Sbjct: 153 SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEF 212
Query: 198 FGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGG+P +T+ G+ GA V L+ SP AKGLF AI++SG A
Sbjct: 213 FGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVA 255
Score = 109 bits (261), Expect = 7e-23
Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGE--------EFGISGSEDCLFINIF 552
L+ P P W+ EA CLQ S + + +FG+S EDCL++NI+
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVS--EDCLYLNIY 127
Query: 553 TPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ + PV+V+ F+TG + S+ E V+VV + +RLG+ G+ TT
Sbjct: 128 APAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTW 186
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D PGN +D + L W+Q NI+ FGGD S V++ G GA +L+ S AKGLF
Sbjct: 187 DQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFH 246
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLLEGLQKVEAGELL 722
+++SG + Y K+ + V DSE LL L+ + ELL
Sbjct: 247 KAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELL 301
>AY907669-1|AAX86044.1| 575|Homo sapiens carboxylesterase 5
protein.
Length = 575
Score = 130 bits (315), Expect = 2e-29
Identities = 80/223 (35%), Positives = 111/223 (49%), Gaps = 8/223 (3%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T G ++G +V + FL +P+ P+G+LRF PQP W ++ A C
Sbjct: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
Query: 84 AQYYV------PMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITY 137
Q M V F SEDCL+LNI+ V+V+ F+ T
Sbjct: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TG 152
Query: 138 NASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINK 197
+AS G EDV++V + +R+G FGF + D PGN KD + AL W+Q NI
Sbjct: 153 SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEF 212
Query: 198 FGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGG+P +T+ G+ GA V L+ SP AKGLF AI++SG A
Sbjct: 213 FGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVA 255
Score = 109 bits (261), Expect = 7e-23
Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGE--------EFGISGSEDCLFINIF 552
L+ P P W+ EA CLQ S + + +FG+S EDCL++NI+
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVS--EDCLYLNIY 127
Query: 553 TPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ + PV+V+ F+TG + S+ E V+VV + +RLG+ G+ TT
Sbjct: 128 APAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTW 186
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D PGN +D + L W+Q NI+ FGGD S V++ G GA +L+ S AKGLF
Sbjct: 187 DQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFH 246
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLLEGLQKVEAGELL 722
+++SG + Y K+ + V DSE LL L+ + ELL
Sbjct: 247 KAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELL 301
>AK056109-1|BAB71094.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 525
Score = 130 bits (315), Expect = 2e-29
Identities = 80/223 (35%), Positives = 111/223 (49%), Gaps = 8/223 (3%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T G ++G +V + FL +P+ P+G+LRF PQP W ++ A C
Sbjct: 35 TRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLC 94
Query: 84 AQYYV------PMRPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITY 137
Q M V F SEDCL+LNI+ V+V+ F+ T
Sbjct: 95 LQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TG 152
Query: 138 NASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINK 197
+AS G EDV++V + +R+G FGF + D PGN KD + AL W+Q NI
Sbjct: 153 SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEF 212
Query: 198 FGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGG+P +T+ G+ GA V L+ SP AKGLF AI++SG A
Sbjct: 213 FGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVA 255
Score = 109 bits (261), Expect = 7e-23
Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNGE--------EFGISGSEDCLFINIF 552
L+ P P W+ EA CLQ S + + +FG+S EDCL++NI+
Sbjct: 70 LRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVS--EDCLYLNIY 127
Query: 553 TPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTE 609
P+ + PV+V+ F+TG + S+ E V+VV + +RLG+ G+ TT
Sbjct: 128 APAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTW 186
Query: 610 DDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFS 669
D PGN +D + L W+Q NI+ FGGD S V++ G GA +L+ S AKGLF
Sbjct: 187 DQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFH 246
Query: 670 AVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLLEGLQKVEAGELL 722
+++SG + Y K+ + V DSE LL L+ + ELL
Sbjct: 247 KAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELL 301
>BC028738-1|AAH28738.1| 518|Homo sapiens NLGN3 protein protein.
Length = 518
Score = 130 bits (314), Expect = 2e-29
Identities = 110/363 (30%), Positives = 172/363 (47%), Gaps = 35/363 (9%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIHTXXXXXXXXXXXX- 123
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKP 161
Query: 124 VIVFLYN-EYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVK 182
V+V+++ Y T N G +VI++T+++RVG GF+S GD GN G+
Sbjct: 162 VMVYIHGGSYMEGTGNMID--GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLL 219
Query: 183 DVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYS 242
D I AL+W+ NI FGG+P +IT+ G GA+ V +L S ++GLF AI+QSG+A S
Sbjct: 220 DQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALS 279
Query: 243 SMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESELMAIHADDSRKYQVP 302
S N +P +A+ + + ++ + L +A ++ E ++ +Y V
Sbjct: 280 SWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI------QPARYHV- 332
Query: 303 ILANGPVVEHD-HPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLTFAD 361
A GPV++ D PD + FL+ + +M+G N E ++ +E + ++ D
Sbjct: 333 --AFGPVIDGDVIPDDPEILMEQGEFLNYD--VMLGVNQGEGLKFVEGVVDPEDGVSGTD 388
Query: 362 RDF 364
D+
Sbjct: 389 FDY 391
Score = 109 bits (261), Expect = 7e-23
Identities = 102/401 (25%), Positives = 171/401 (42%), Gaps = 44/401 (10%)
Query: 504 MPPVPHKGWEGTYEAYVEKPTCLQ--------------FSSRMRNGEEFGISGSEDCLFI 549
+PP P W G A P C Q F++ + + +EDCL++
Sbjct: 85 LPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYL 144
Query: 550 NIFTPSL-----KGSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLG 604
N++ P+ G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG
Sbjct: 145 NVYVPTEDDIRDSGAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLG 203
Query: 605 YLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKA 664
+L+T D GN GL D + L+W+ +NI FGGD R++V G+ GA+ L S +
Sbjct: 204 FLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHS 263
Query: 665 KGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRN 724
+GLF +IQSG+ L + P + D+ +++ L++ A EL+
Sbjct: 264 EGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQ 323
Query: 725 EIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSRE 780
+I F P I+ P++PE L E G +N V++G N E
Sbjct: 324 DI---------QPARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDVMLGVNQGE 369
Query: 781 GLDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHY 840
GL + VS + V + Y + G K+ ++ ++F + D +
Sbjct: 370 GLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRD 425
Query: 841 G-NVMEYTVYAGDVLQMYALQKAVT-KLSAELQSNLYFYMF 879
T+ A + VT L A S YFY F
Sbjct: 426 NPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAF 466
>AF106005-1|AAF14185.1| 288|Homo sapiens carboxylesterase-related
protein protein.
Length = 288
Score = 129 bits (312), Expect = 4e-29
Identities = 84/233 (36%), Positives = 121/233 (51%), Gaps = 11/233 (4%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK--- 77
+V+T GKV G + + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 26 VVDTVHGKVLGKFISLEGFAQPVAVFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATLYP 85
Query: 78 ----KERKQCAQYYVPM--RPVDEVGFCGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNE 131
++ ++ Q + + + SEDCL+LNI+T V+V+++
Sbjct: 86 PMFTQDPRRGGQLISELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLP-VMVWIHGG 144
Query: 132 YFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWI 191
+ AS G E+V++VTI +R+G +GF S GD+ PGN G D + AL W+
Sbjct: 145 GLMVGA-ASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHWV 203
Query: 192 QSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
Q NI FGGNP +T+ G G V +L+ SP AK LF AI +SG A +S+
Sbjct: 204 QDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVALTSV 256
Score = 103 bits (247), Expect = 3e-21
Identities = 67/195 (34%), Positives = 93/195 (47%), Gaps = 15/195 (7%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSR---------MRNGEEFGISGSEDCLFINI 551
L+ PP P + W A + P Q R E + SEDCL++NI
Sbjct: 64 LRFTPPQPAEPWSFVKNATLYPPMFTQDPRRGGQLISELFTNRKENIPLKLSEDCLYLNI 123
Query: 552 FTPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLT 607
+TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +
Sbjct: 124 YTPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFS 181
Query: 608 TEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGL 667
T D+ PGN G D L L W+QDNI SFGG+ V++ G G L+ S AK L
Sbjct: 182 TGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNL 241
Query: 668 FSAVMIQSGTTLEAM 682
F + +SG L ++
Sbjct: 242 FHRAISESGVALTSV 256
>Y09616-1|CAA70831.1| 559|Homo sapiens carboxylesterase protein.
Length = 559
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 36 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 95
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 96 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 153
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 154 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 213
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 214 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 257
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 71 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 130
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 131 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 189
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 190 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 249
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 250 AIMESGVAL 258
>U60553-1|AAB03611.1| 550|Homo sapiens carboxylesterase protein.
Length = 550
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 27 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 86
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 87 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 144
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 145 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 204
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 205 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 248
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 62 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 121
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 122 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 180
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 181 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 240
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 241 AIMESGVAL 249
>D50579-1|BAA23606.1| 559|Homo sapiens carboxylesterase precursor
protein.
Length = 559
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 36 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 95
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 96 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 153
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 154 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 213
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 214 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 257
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 71 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 130
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 131 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 189
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 190 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 249
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 250 AIMESGVAL 258
>BC098417-1|AAH98417.1| 587|Homo sapiens CES2 protein protein.
Length = 587
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 80 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 139
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 140 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 197
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 198 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 257
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 258 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 301
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 115 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 174
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 175 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 233
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 234 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 293
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 294 AIMESGVAL 302
>BC071874-1|AAH71874.1| 586|Homo sapiens CES2 protein protein.
Length = 586
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 79 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 138
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 139 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 196
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 197 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 256
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 257 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 300
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 114 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 173
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 174 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 232
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 233 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 292
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 293 AIMESGVAL 301
>BC032095-1|AAH32095.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 100 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 159
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 160 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 217
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 218 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 277
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 278 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 321
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 135 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 194
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 195 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 253
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 254 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 313
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 314 AIMESGVAL 322
>AY851164-1|AAW29943.1| 623|Homo sapiens carboxylesterase 2
(intestine, liver) protein.
Length = 623
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 100 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 159
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 160 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 217
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 218 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 277
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 278 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 321
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 135 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 194
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 195 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 253
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 254 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 313
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 314 AIMESGVAL 322
>AK222724-1|BAD96444.1| 582|Homo sapiens carboxylesterase 2 isoform
1 variant protein.
Length = 582
Score = 126 bits (304), Expect = 4e-28
Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)
Query: 24 TNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQC 83
T++G+V G V + +FL IP+ K P+G LRF P+P E W+ V + C
Sbjct: 59 THTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMC 118
Query: 84 AQYYVPMRPVDEVGF-------CGSEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRIT 136
Q + F SEDCL+L+I+T V+V+++ +
Sbjct: 119 LQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT-PAHSHEGSNLPVMVWIHGGAL-VF 176
Query: 137 YNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNIN 196
AS G E+V++V I +R+G GF S GD GN G D + AL+W+Q NI
Sbjct: 177 GMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIA 236
Query: 197 KFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTA 240
FGGNP ++T+ G+ G V L+ SP ++GLF GAI++SG A
Sbjct: 237 HFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVA 280
Score = 103 bits (246), Expect = 4e-21
Identities = 65/189 (34%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQFSSRMRNG--EEFGI-----SGSEDCLFINIFT 553
L+ PP P + W G + CLQ + + + +F + S SEDCL+++I+T
Sbjct: 94 LRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYT 153
Query: 554 P--SLKGS-APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTED 610
P S +GS PV+V+ + G SL E VVVV I +RLG+LG+ +T D
Sbjct: 154 PAHSHEGSNLPVMVWIHGGALVFGM-ASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGD 212
Query: 611 DVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSA 670
GN G D + L+W+Q NI FGG+ RV++ G G +L+ S ++GLF
Sbjct: 213 KHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHG 272
Query: 671 VMIQSGTTL 679
+++SG L
Sbjct: 273 AIMESGVAL 281
>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
Length = 2768
Score = 120 bits (288), Expect = 4e-26
Identities = 91/297 (30%), Positives = 147/297 (49%), Gaps = 20/297 (6%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDEVGFCGSEDCL 105
FL +PY P+ RF+AP+P WT +A K R C Q R G SEDCL
Sbjct: 2228 FLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--PGTRTSTSPGV--SEDCL 2282
Query: 106 HLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKE-DVILVTISHRVGT 164
+LN+ V+VF +N R F ++I+VT S+RVG
Sbjct: 2283 YLNVFIPQNVAPNAS---VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGV 2339
Query: 165 FGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSP 224
FGF+S G + GN G+ D + AL W+Q++I FGG+P +++L GGA + I L +
Sbjct: 2340 FGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTA 2399
Query: 225 KAKG--LFSGAILQSGTAYS--SMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAA 280
+A LF A+L G+A S ++ + + + +A+A+A+ + +S+S + +S L A
Sbjct: 2400 RATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPA 2459
Query: 281 PKISESELMAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVEIPIMIG 337
+++++ + Y P++ +G + P A KR L VE+ ++IG
Sbjct: 2460 NVLNDAQTKLLAVSGPFHYWGPVI-DGHFLR--EPPARALKRS----LXVEVDLLIG 2509
Score = 101 bits (241), Expect = 2e-20
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 10/216 (4%)
Query: 512 WEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTP-SLKGSAPVVVFDYNDN 570
W G+++A + +C Q +R G+S EDCL++N+F P ++ +A V+VF +N
Sbjct: 2251 WTGSWDASKPRASCWQPGTRTSTSP--GVS--EDCLYLNVFIPQNVAPNASVLVFFHNTM 2306
Query: 571 FRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWI 629
R G F G ++VVT S+R+G+ G+L++ + GN GL D + L W+
Sbjct: 2307 DREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWV 2366
Query: 630 QDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKG--LFSAVMIQSGTTLE--AMYFY 685
Q +I+ FGGD RVS+ +RGGA +A L + +A LF ++ G+ L A+ +
Sbjct: 2367 QTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISH 2426
Query: 686 RTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGEL 721
+ +A + + S+ ++ L++ A L
Sbjct: 2427 ERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVL 2462
>M55509-1|AAA35650.1| 507|Homo sapiens carboxylesterase protein.
Length = 507
Score = 120 bits (288), Expect = 4e-26
Identities = 119/420 (28%), Positives = 184/420 (43%), Gaps = 32/420 (7%)
Query: 57 GALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDE--------VGFCGSEDCLHLN 108
G LRF PQP E W+ V NA C Q + + E + SEDCL+LN
Sbjct: 1 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 60
Query: 109 IHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFV 168
I+T V+V+++ + AS G E+V++VTI +R+G +GF
Sbjct: 61 IYT-PADLTKKNRLPVMVWIHGGGLMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFF 118
Query: 169 SFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKG 228
S GD+ GN G D + AL+W+Q NI FGGNP +T+ G+ G V +L+ SP AK
Sbjct: 119 STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN 178
Query: 229 LFSGAILQSGTAYSSMFFNT-KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESE 287
LF AI +SG A +S+ K A IA K + SA + L ++ E+
Sbjct: 179 LFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETT 238
Query: 288 L----MAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNT 340
L +++ + P+L G V++ ++ K PE+ + +P M+G N
Sbjct: 239 LKMKFLSLDLQGDPRESQPLL--GTVID----GMLLLKTPEELQAERNFHTVPYMVGINK 292
Query: 341 RESIEMMERYLRK-PQYLTFADRDFLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGY 399
+E ++ L P D+ M + Y + E I E + YL
Sbjct: 293 QEFGWLIPMQLMSYPLSEGQLDQKTAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTD 348
Query: 400 VKISKPGEFMTYMTDINTFYSVDYAVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
+ K F+ + D+ F V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 349 DTVKKKDLFLDLIADV-MFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 407
Score = 109 bits (261), Expect = 7e-23
Identities = 118/474 (24%), Positives = 198/474 (41%), Gaps = 45/474 (9%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 3 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 62
Query: 553 TPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTT 608
TP+ K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T
Sbjct: 63 TPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFST 120
Query: 609 EDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLF 668
D+ GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF
Sbjct: 121 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 180
Query: 669 SAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIG 727
+ +SG L ++ + K A + +T S V++ L++ ELL +
Sbjct: 181 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 240
Query: 728 V-LDNDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSRE-GL 782
+ + + + D + P T+ ++ PE + VP ++G N +E G
Sbjct: 241 MKFLSLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGW 297
Query: 783 DLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGN 842
+ ++ P L Q+++ + ++Y V KE + E Y
Sbjct: 298 LIPMQLMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKK 353
Query: 843 VMEYTVYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTEN 902
+ DV M+ + + + + YM++F Y S S K +
Sbjct: 354 KDLFLDLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKT 403
Query: 903 HGATIGDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 404 VIGDHGDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 449
>AY358504-1|AAQ88868.1| 545|Homo sapiens carboxylesterase Hlo
protein.
Length = 545
Score = 118 bits (285), Expect = 8e-26
Identities = 80/261 (30%), Positives = 129/261 (49%), Gaps = 13/261 (4%)
Query: 101 SEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVTISH 160
SEDCL+LN++ ++ F + I AS G D +E V+LV + H
Sbjct: 217 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF--IVGAASSYEGSDLAAREKVVLVFLQH 274
Query: 161 RVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDIL 220
R+G FGF+S D GN G+ D + AL+W+Q NI FGG+P +TL GQ GA + L
Sbjct: 275 RLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGL 334
Query: 221 LHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAA 280
+ SP A GLF AI QSGTA +F + P A +A + +++ ++ L +++
Sbjct: 335 MMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSG 394
Query: 281 PKIS--ESELMAIHADDSRKYQVPILANGPVVE----HDHPDAVITKRPEDSFLDVEIPI 334
K+ +++ + + R + I + PVV+ D P ++T+ S +P
Sbjct: 395 TKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSS-----VPY 449
Query: 335 MIGYNTRESIEMMERYLRKPQ 355
++G N E ++ + K Q
Sbjct: 450 LLGVNNLEFNWLLPYNITKEQ 470
Score = 115 bits (277), Expect = 8e-25
Identities = 74/247 (29%), Positives = 126/247 (51%), Gaps = 15/247 (6%)
Query: 543 SEDCLFINIFTPSLKGS---APVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHR 599
SEDCL++N++ P+ PV+V+ F G S D E VV+V + HR
Sbjct: 217 SEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYE-GSDLAAREKVVLVFLQHR 275
Query: 600 LGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
LG+ G+L+T+D GN GL D + L+W+Q+NI +FGGD V++ G GA L+
Sbjct: 276 LGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLM 335
Query: 660 YSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAG 719
S A GLF + QSGT L ++ P A + + + +++L+ L+ +
Sbjct: 336 MSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGT 395
Query: 720 ELLR--NEIGVLDNDEFENDQHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVL 773
+++R N++ L + + + + +P ++ P++P ++T G V+ VP L
Sbjct: 396 KVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLT----QGK-VSSVPYL 450
Query: 774 IGFNSRE 780
+G N+ E
Sbjct: 451 LGVNNLE 457
Score = 37.9 bits (84), Expect = 0.18
Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 22 VETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNA 76
V T G ++G ++ + FL +P+ + P+G LRF P+P E W + +A
Sbjct: 93 VVTKYGTLQGKQMH--VGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDA 145
>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
Length = 1124
Score = 118 bits (285), Expect = 8e-26
Identities = 91/297 (30%), Positives = 147/297 (49%), Gaps = 20/297 (6%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDEVGFCGSEDCL 105
FL +PY P+ RF+AP+P WT +A K R C Q R G SEDCL
Sbjct: 584 FLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--PGTRTSTSPGV--SEDCL 638
Query: 106 HLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKE-DVILVTISHRVGT 164
+LN+ V+VF +N R F ++I+VT S+RVG
Sbjct: 639 YLNVFIPQNVAPNAS---VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGV 695
Query: 165 FGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSP 224
FGF+S G + GN G+ D + AL W+Q++I FGG+P +++L GGA + I L +
Sbjct: 696 FGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTA 755
Query: 225 KAKG--LFSGAILQSGTAYS--SMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAA 280
+A LF A+L G+A S ++ + + + +A+A+A+ + +S+S + +S L A
Sbjct: 756 RATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPA 815
Query: 281 PKISESELMAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVEIPIMIG 337
+++++ + Y P++ +G + P A KR L VE+ ++IG
Sbjct: 816 NVLNDAQTKLLAVSGPFHYWGPVI-DGHFLR--EPPARALKRS----LWVEVDLLIG 865
Score = 101 bits (241), Expect = 2e-20
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 10/216 (4%)
Query: 512 WEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTP-SLKGSAPVVVFDYNDN 570
W G+++A + +C Q +R G+S EDCL++N+F P ++ +A V+VF +N
Sbjct: 607 WTGSWDASKPRASCWQPGTRTSTSP--GVS--EDCLYLNVFIPQNVAPNASVLVFFHNTM 662
Query: 571 FRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWI 629
R G F G ++VVT S+R+G+ G+L++ + GN GL D + L W+
Sbjct: 663 DREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWV 722
Query: 630 QDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKG--LFSAVMIQSGTTLE--AMYFY 685
Q +I+ FGGD RVS+ +RGGA +A L + +A LF ++ G+ L A+ +
Sbjct: 723 QTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISH 782
Query: 686 RTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGEL 721
+ +A + + S+ ++ L++ A L
Sbjct: 783 ERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVL 818
>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
variant protein.
Length = 1574
Score = 118 bits (285), Expect = 8e-26
Identities = 91/297 (30%), Positives = 147/297 (49%), Gaps = 20/297 (6%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDEVGFCGSEDCL 105
FL +PY P+ RF+AP+P WT +A K R C Q R G SEDCL
Sbjct: 1034 FLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--PGTRTSTSPGV--SEDCL 1088
Query: 106 HLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKE-DVILVTISHRVGT 164
+LN+ V+VF +N R F ++I+VT S+RVG
Sbjct: 1089 YLNVFIPQNVAPNAS---VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGV 1145
Query: 165 FGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSP 224
FGF+S G + GN G+ D + AL W+Q++I FGG+P +++L GGA + I L +
Sbjct: 1146 FGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTA 1205
Query: 225 KAKG--LFSGAILQSGTAYS--SMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAA 280
+A LF A+L G+A S ++ + + + +A+A+A+ + +S+S + +S L A
Sbjct: 1206 RATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPA 1265
Query: 281 PKISESELMAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVEIPIMIG 337
+++++ + Y P++ +G + P A KR L VE+ ++IG
Sbjct: 1266 NVLNDAQTKLLAVSGPFHYWGPVI-DGHFLR--EPPARALKRS----LWVEVDLLIG 1315
Score = 101 bits (241), Expect = 2e-20
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 10/216 (4%)
Query: 512 WEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTP-SLKGSAPVVVFDYNDN 570
W G+++A + +C Q +R G+S EDCL++N+F P ++ +A V+VF +N
Sbjct: 1057 WTGSWDASKPRASCWQPGTRTSTSP--GVS--EDCLYLNVFIPQNVAPNASVLVFFHNTM 1112
Query: 571 FRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWI 629
R G F G ++VVT S+R+G+ G+L++ + GN GL D + L W+
Sbjct: 1113 DREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWV 1172
Query: 630 QDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKG--LFSAVMIQSGTTLE--AMYFY 685
Q +I+ FGGD RVS+ +RGGA +A L + +A LF ++ G+ L A+ +
Sbjct: 1173 QTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISH 1232
Query: 686 RTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGEL 721
+ +A + + S+ ++ L++ A L
Sbjct: 1233 ERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVL 1268
>X52973-1|CAA37147.1| 503|Homo sapiens monocyte/macrophage
serine-esterase 1 protein.
Length = 503
Score = 117 bits (281), Expect = 2e-25
Identities = 115/415 (27%), Positives = 181/415 (43%), Gaps = 31/415 (7%)
Query: 61 FKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHTX 112
F PQP E W+ V NA C Q + + E + SEDCL+LNI+T
Sbjct: 2 FTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT- 60
Query: 113 XXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGD 172
V+V+++ + AS G E+V++VTI +R+G +GF S GD
Sbjct: 61 PADLTKKNRLPVMVWIHGGGLMVG-AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGD 119
Query: 173 DLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSG 232
+ GN G D + AL+W+Q NI FGGNP +T+ G+ G V +L+ SP AK LF
Sbjct: 120 EHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHR 179
Query: 233 AILQSGTAYSSMFFNT-KPKDRALAIAEVLERKLSNSAQFISELGSIAAPKISESEL--- 288
AI +SG A +S+ K A IA K + SA + L ++ E+ L
Sbjct: 180 AISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMK 239
Query: 289 -MAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVE---IPIMIGYNTRESI 344
+++ + P+L G V++ ++ K PE+ + +P M+G N +E
Sbjct: 240 FLSLDLQGDPRESQPLL--GTVID----GMLLLKTPEELQAERNFHTVPYMVGINKQEFG 293
Query: 345 EMMERYLRKPQYLTFADRDFLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISK 404
++ + P D+ M + Y + E I E + YL + K
Sbjct: 294 WLIPMLMSYPLSEGQLDQKTAMSL-LWKSYPL---VCIAKELIPEATEKYLGGTDDTVKK 349
Query: 405 PGEFMTYMTDINTFYSVDYAVRRYLNESSAQIYYYAFDY--SGDLNMRKQNILKD 457
F+ + D+ F V R ++ A Y Y F Y S +M+ + ++ D
Sbjct: 350 KDLFLDLIADV-MFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 403
Score = 107 bits (258), Expect = 2e-22
Identities = 117/469 (24%), Positives = 195/469 (41%), Gaps = 44/469 (9%)
Query: 505 PPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIFTPS- 555
PP P + W A P C Q S N +E + SEDCL++NI+TP+
Sbjct: 4 PPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPAD 63
Query: 556 --LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHRLGLLGYLTTEDDV 612
K PV+V+ + G + TY E VVVVTI +RLG+ G+ +T D+
Sbjct: 64 LTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEH 121
Query: 613 IPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVM 672
GN G D + L+W+QDNI SFGG+ V++ G G L+ S AK LF +
Sbjct: 122 SGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAI 181
Query: 673 IQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGV-LD 730
+SG L ++ + K A + +T S V++ L++ ELL + +
Sbjct: 182 SESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFL 241
Query: 731 NDEFENDQHSTFPFAPTIEPENPEAVITNLPEN---GHIVNDVPVLIGFNSREGLDLTSH 787
+ + + D + P T+ ++ PE + VP ++G N +E L
Sbjct: 242 SLDLQGDPRESQPLLGTV---IDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPM 298
Query: 788 FLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYT 847
++ P L Q+++ + ++Y V KE + E Y +
Sbjct: 299 LMSYP-LSEGQLDQKTAMSLLWKSYPLV---CIAKELIPEATEKYLGGTDDTVKKKDLFL 354
Query: 848 VYAGDVLQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATI 907
DV M+ + + + + YM++F Y S S K +
Sbjct: 355 DLIADV--MFGVPSVIVARN-HRDAGAPTYMYEF-------QYRPSFSSDMKPKTVIGDH 404
Query: 908 GDELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
GDEL + ++ + ++++L K +++ W NFA++ NP
Sbjct: 405 GDELFSVFGAPFLKEGASE--------EEIRLSKMVMKFWANFARNGNP 445
>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
Length = 2767
Score = 116 bits (280), Expect = 3e-25
Identities = 90/297 (30%), Positives = 146/297 (49%), Gaps = 20/297 (6%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDEVGFCGSEDCL 105
FL +PY P+ F+AP+P WT +A K R C Q R G SEDCL
Sbjct: 2227 FLGVPYAAPPLAERHFQAPEPLN-WTGSWDASKPRASCWQ--PGTRTSTSPGV--SEDCL 2281
Query: 106 HLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKE-DVILVTISHRVGT 164
+LN+ V+VF +N R F ++I+VT S+RVG
Sbjct: 2282 YLNVFIPQNVAPNAS---VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGV 2338
Query: 165 FGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSP 224
FGF+S G + GN G+ D + AL W+Q++I FGG+P +++L GGA + I L +
Sbjct: 2339 FGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTA 2398
Query: 225 KAKG--LFSGAILQSGTAYS--SMFFNTKPKDRALAIAEVLERKLSNSAQFISELGSIAA 280
+A LF A+L G+A S ++ + + + +A+A+A+ + +S+S + +S L A
Sbjct: 2399 RATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPA 2458
Query: 281 PKISESELMAIHADDSRKYQVPILANGPVVEHDHPDAVITKRPEDSFLDVEIPIMIG 337
+++++ + Y P++ +G + P A KR L VE+ ++IG
Sbjct: 2459 NVLNDAQTKLLAVSGPFHYWGPVI-DGHFLR--EPPARALKRS----LWVEVDLLIG 2508
Score = 101 bits (241), Expect = 2e-20
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 10/216 (4%)
Query: 512 WEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTP-SLKGSAPVVVFDYNDN 570
W G+++A + +C Q +R G+S EDCL++N+F P ++ +A V+VF +N
Sbjct: 2250 WTGSWDASKPRASCWQPGTRTSTSP--GVS--EDCLYLNVFIPQNVAPNASVLVFFHNTM 2305
Query: 571 FRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWI 629
R G F G ++VVT S+R+G+ G+L++ + GN GL D + L W+
Sbjct: 2306 DREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWV 2365
Query: 630 QDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKG--LFSAVMIQSGTTLE--AMYFY 685
Q +I+ FGGD RVS+ +RGGA +A L + +A LF ++ G+ L A+ +
Sbjct: 2366 QTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISH 2425
Query: 686 RTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGEL 721
+ +A + + S+ ++ L++ A L
Sbjct: 2426 ERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVL 2461
>BC127887-1|AAI27888.1| 422|Homo sapiens Unknown (protein for
IMAGE:40133565) protein.
Length = 422
Score = 114 bits (275), Expect = 1e-24
Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 13/233 (5%)
Query: 46 FLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKERKQCAQYYVPMRPVDEVGFCGSEDCL 105
FL +PY P+ RF+AP+P WT +A K R C Q R G SEDCL
Sbjct: 190 FLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASCWQ--PGTRTSTSPGV--SEDCL 244
Query: 106 HLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKE-DVILVTISHRVGT 164
+LN+ V+VF +N R F ++I+VT S+RVG
Sbjct: 245 YLNVFIPQNVAPNAS---VLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGV 301
Query: 165 FGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSP 224
FGF+S G + GN G+ D + AL W+Q++I FGG+P +++L GGA + I L +
Sbjct: 302 FGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTA 361
Query: 225 KAKG--LFSGAILQSGTAYS--SMFFNTKPKDRALAIAEVLERKLSNSAQFIS 273
+A LF A+L G+A S ++ + + + +A+A+A+ + +S+S + +S
Sbjct: 362 RATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVS 414
Score = 99 bits (238), Expect = 4e-20
Identities = 59/172 (34%), Positives = 95/172 (55%), Gaps = 8/172 (4%)
Query: 512 WEGTYEAYVEKPTCLQFSSRMRNGEEFGISGSEDCLFINIFTP-SLKGSAPVVVFDYNDN 570
W G+++A + +C Q +R G+S EDCL++N+F P ++ +A V+VF +N
Sbjct: 213 WTGSWDASKPRASCWQPGTRTSTSP--GVS--EDCLYLNVFIPQNVAPNASVLVFFHNTM 268
Query: 571 FRTGFNGSLTYAPDFFVEEG-VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWI 629
R G F G ++VVT S+R+G+ G+L++ + GN GL D + L W+
Sbjct: 269 DREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWV 328
Query: 630 QDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKG--LFSAVMIQSGTTL 679
Q +I+ FGGD RVS+ +RGGA +A L + +A LF ++ G+ L
Sbjct: 329 QTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSAL 380
>AB023168-1|BAA76795.2| 679|Homo sapiens KIAA0951 protein protein.
Length = 679
Score = 114 bits (275), Expect = 1e-24
Identities = 116/456 (25%), Positives = 189/456 (41%), Gaps = 45/456 (9%)
Query: 561 PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNNGLR 620
PV+V+ + ++ G G++ V+V+TI++RLG+LG+L+T D GN GL
Sbjct: 30 PVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 88
Query: 621 DFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGTTLE 680
D + L+WI++N+ +FGGD RV++ G+ GA+ L S ++GLF +IQSGT L
Sbjct: 89 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 148
Query: 681 AMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFENDQHS 740
+ P + D+ ++E L+ EL++ I
Sbjct: 149 SWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI---------TPATY 199
Query: 741 TFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLVS 796
F P I+ P++P+ L E G +N +++G N EGL + V+
Sbjct: 200 HIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDIMLGVNQGEGLKFVDGIVDNEDGVT 254
Query: 797 HQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTVYAGDVLQM 856
+ V + Y + G +E K + + + ++ ++ Q
Sbjct: 255 PNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDH--QW 312
Query: 857 YALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELCYLHL 916
A A L A+ S YFY F YH + S K + GDE+ Y+
Sbjct: 313 VAPAVATADLHAQYGSPTYFYAF----------YHHCQ-SEMKPSWADSAHGDEVPYVFG 361
Query: 917 CNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV--------LNG 967
I T ++ DV L ++ WTNFAK+ +P P DT
Sbjct: 362 IPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE 419
Query: 968 LIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ W + + YLHI KPR+ + + FW
Sbjct: 420 VAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 453
Score = 105 bits (253), Expect = 6e-22
Identities = 67/214 (31%), Positives = 113/214 (52%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++TI++R+G GF+S GD GN G+ D I AL+WI+ N+ FGG+P ++T+ G
Sbjct: 58 NVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSG 117
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSGTA SS N +P +A+ + + ++
Sbjct: 118 AGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDM 177
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L + ++ + + Y + A GPV++ D PD + FL+
Sbjct: 178 VECLKNKNYKELIQQTI------TPATYHI---AFGPVIDGDVIPDDPQILMEQGEFLNY 228
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ ++ + +T D DF
Sbjct: 229 D--IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDF 260
>AY358562-1|AAQ88925.1| 816|Homo sapiens NLGN4 protein.
Length = 816
Score = 114 bits (274), Expect = 2e-24
Identities = 116/457 (25%), Positives = 188/457 (41%), Gaps = 48/457 (10%)
Query: 561 PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNNGLR 620
PV+V+ + ++ G G++ V+V+TI++RLG+LG+L+T D GN GL
Sbjct: 168 PVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 226
Query: 621 DFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGTTLE 680
D + L+WI++N+ +FGGD RV++ G+ GA+ L S ++GLF +IQSGT L
Sbjct: 227 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 286
Query: 681 AMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFENDQHS 740
+ P + D+ ++E L+ EL++ I
Sbjct: 287 SWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTI---------TPATY 337
Query: 741 TFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLVS 796
F P I+ P++P+ L E G +N +++G N EGL + V+
Sbjct: 338 HIAFGPVIDGDVIPDDPQI----LMEQGEFLN-YDIMLGVNQGEGLKFVDGIVDNEDGVT 392
Query: 797 HQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFED-KSVHYGNVMEYTVYAGDVLQ 855
N F + + G K+ ++ ++F + D T+ A
Sbjct: 393 ----PNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDH 448
Query: 856 MYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELCYLH 915
+ L A+ S YFY F YH + S K + GDE+ Y+
Sbjct: 449 QWVAPAVAADLHAQYGSPTYFYAF----------YHHCQ-SEMKPSWADSAHGDEVPYVF 497
Query: 916 LCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV--------LN 966
I T ++ DV L ++ WTNFAK+ +P P DT
Sbjct: 498 GIPMIGPT--ELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFE 555
Query: 967 GLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
+ W + + YLHI KPR+ + + FW
Sbjct: 556 EVAWSKYNPKDQL--YLHIGLKPRVRDHYRATKVAFW 590
Score = 105 bits (253), Expect = 6e-22
Identities = 67/214 (31%), Positives = 113/214 (52%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++TI++R+G GF+S GD GN G+ D I AL+WI+ N+ FGG+P ++T+ G
Sbjct: 196 NVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSG 255
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSGTA SS N +P +A+ + + ++
Sbjct: 256 AGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDM 315
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L + ++ + + Y + A GPV++ D PD + FL+
Sbjct: 316 VECLRNKNYKELIQQTI------TPATYHI---AFGPVIDGDVIPDDPQILMEQGEFLNY 366
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ ++ + +T D DF
Sbjct: 367 D--IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDF 398
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 5/69 (7%)
Query: 21 IVETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAK 77
+V TN GK+ GL I+ + Y L +PY P G RF+ P+P WT + N
Sbjct: 28 VVNTNYGKIRGLRTPLPNEILGPVEQY--LGVPYASPPTGERRFQPPEPPSSWTGIRNTT 85
Query: 78 KERKQCAQY 86
+ C Q+
Sbjct: 86 QFAAVCPQH 94
>BC064573-1|AAH64573.1| 442|Homo sapiens FLJ37464 protein protein.
Length = 442
Score = 112 bits (269), Expect = 7e-24
Identities = 102/403 (25%), Positives = 183/403 (45%), Gaps = 35/403 (8%)
Query: 561 PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNNGLR 620
PV+V+ F G S D E VV+V + HRLG+ G+L+T+D GN GL
Sbjct: 15 PVMVWFPGGAFIVGAASSYE-GSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLL 73
Query: 621 DFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGTTLE 680
D + L+W+Q+NI +FGGD V++ G GA L+ S A GLF + QSGT L
Sbjct: 74 DQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALF 133
Query: 681 AMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLR--NEIGVLDNDEFENDQ 738
++ R P A + + + +++L+ L+ + +++R N++ L + + +
Sbjct: 134 RLFITRNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPE 193
Query: 739 HSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQL 794
+ +P ++ P++P ++T G V+ VP L+G N+ E L + + P
Sbjct: 194 EIIWSMSPVVDGVVIPDDPLVLLT----QGK-VSSVPYLLGVNNLEFNWLLPYIMKFPLN 248
Query: 795 VSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTVYAGDVL 854
+E I + + +N KE ++E Y ++ + H ++ + D++
Sbjct: 249 RQAMRKETITKM-LWSTRTLLN---ITKEQVPLVVEEYLDNVNEHDWKMLRNRMM--DIV 302
Query: 855 QMYALQKAVTKLS-AELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELCY 913
Q A + + + L Y+++F H +R K GA GDE+ +
Sbjct: 303 QDATFVYATLQTAHYHRDAGLPVYLYEF--------EHHARGIIVKPRTDGADHGDEMYF 354
Query: 914 LHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
L + L + ++ L +M++ W NFA++ NP
Sbjct: 355 L-----FGGPFATGLSMG---KEKALSLQMMKYWANFARTGNP 389
Score = 110 bits (265), Expect = 2e-23
Identities = 89/345 (25%), Positives = 151/345 (43%), Gaps = 24/345 (6%)
Query: 139 ASKEYGPDFFMKEDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKF 198
AS G D +E V+LV + HR+G FGF+S D GN G+ D + AL+W+Q NI F
Sbjct: 30 ASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAF 89
Query: 199 GGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIA 258
GG+P +TL GQ GA + L+ SP A GLF AI QSGTA +F P A +A
Sbjct: 90 GGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITRNPLKVAKKVA 149
Query: 259 EVLERKLSNSAQFISELGSIAAPKIS--ESELMAIHADDSRKYQVPILANGPVVE----H 312
+ +++ ++ L +++ K+ +++ + + R + I + PVV+
Sbjct: 150 HLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIP 209
Query: 313 DHPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLTFADRDFLMMFPIRV 372
D P ++T+ S +P ++G N E ++ ++ P ++ +
Sbjct: 210 DDPLVLLTQGKVSS-----VPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWST 264
Query: 373 DYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYSVDYAVRRYLNES 432
+ ++E D E + + M + D TF Y ++
Sbjct: 265 RTLLNITKEQVPLVVEEYLDNVNEHDWKMLR--NRMMDIVQDA-TFVYATLQTAHYHRDA 321
Query: 433 SAQIYYYAFDYSGDLNMRKQNILKDAMILEGTWGASIGDELCYLF 477
+Y Y F++ + ++ T GA GDE+ +LF
Sbjct: 322 GLPVYLYEFEHHA----------RGIIVKPRTDGADHGDEMYFLF 356
>BC051715-1|AAH51715.1| 828|Homo sapiens neuroligin 3 protein.
Length = 828
Score = 110 bits (264), Expect = 3e-23
Identities = 118/465 (25%), Positives = 193/465 (41%), Gaps = 49/465 (10%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 178 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 236
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 237 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 296
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 297 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 347
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 348 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 402
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 403 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 458
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDEL 911
+ VT L A S YFY F YH + S K A GDE+
Sbjct: 459 TDHQWVEPSVVTADLHARYGSPTYFYAF----------YHHCQ-SLMKPAWSDAAHGDEV 507
Query: 912 CYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV------ 964
Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 508 PYVFGVPMVGPT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKA 565
Query: 965 --LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFL 1007
+ W + YLHI KPR+ + + FW + +
Sbjct: 566 NRFEEVAWSKYNPRDQL--YLHIGLKPRVRDHYRATKVAFWKHLV 608
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 209 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 268
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 269 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 328
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 329 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 379
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 380 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 411
Score = 37.1 bits (82), Expect = 0.32
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPYWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIH 110
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
>AF217413-2|AAF71232.1| 828|Homo sapiens neuroligin 3 isoform
protein.
Length = 828
Score = 110 bits (264), Expect = 3e-23
Identities = 118/465 (25%), Positives = 193/465 (41%), Gaps = 49/465 (10%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 178 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 236
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 237 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 296
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 297 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 347
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 348 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 402
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 403 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 458
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDEL 911
+ VT L A S YFY F YH + S K A GDE+
Sbjct: 459 TDHQWVEPSVVTADLHARYGSPTYFYAF----------YHHCQ-SLMKPAWSDAAHGDEV 507
Query: 912 CYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV------ 964
Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 508 PYVFGVPMVGPT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKA 565
Query: 965 --LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFL 1007
+ W + YLHI KPR+ + + FW + +
Sbjct: 566 NRFEEVAWSKYNPRDQL--YLHIGLKPRVRDHYRATKVAFWKHLV 608
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 209 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 268
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 269 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 328
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 329 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 379
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 380 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 411
Score = 38.3 bits (85), Expect = 0.14
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIH 110
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
>AF217413-1|AAF71233.1| 848|Homo sapiens neuroligin 3 isoform
protein.
Length = 848
Score = 110 bits (264), Expect = 3e-23
Identities = 118/465 (25%), Positives = 193/465 (41%), Gaps = 49/465 (10%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 198 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 256
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 257 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 316
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 317 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 367
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 368 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 422
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 423 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 478
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDEL 911
+ VT L A S YFY F YH + S K A GDE+
Sbjct: 479 TDHQWVEPSVVTADLHARYGSPTYFYAF----------YHHCQ-SLMKPAWSDAAHGDEV 527
Query: 912 CYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV------ 964
Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 528 PYVFGVPMVGPT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKA 585
Query: 965 --LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFL 1007
+ W + YLHI KPR+ + + FW + +
Sbjct: 586 NRFEEVAWSKYNPRDQL--YLHIGLKPRVRDHYRATKVAFWKHLV 628
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 229 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 288
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 289 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 348
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 349 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 399
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 400 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 431
Score = 38.3 bits (85), Expect = 0.14
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIH 110
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
>AB040913-1|BAA96004.1| 682|Homo sapiens KIAA1480 protein protein.
Length = 682
Score = 110 bits (264), Expect = 3e-23
Identities = 118/465 (25%), Positives = 193/465 (41%), Gaps = 49/465 (10%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 32 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 90
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 91 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 150
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 151 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 201
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 202 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 256
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 257 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 312
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDEL 911
+ VT L A S YFY F YH + S K A GDE+
Sbjct: 313 TDHQWVEPSVVTADLHARYGSPTYFYAF----------YHHCQ-SLMKPAWSDAAHGDEV 361
Query: 912 CYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV------ 964
Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 362 PYVFGVPMVGPT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKA 419
Query: 965 --LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFL 1007
+ W + YLHI KPR+ + + FW + +
Sbjct: 420 NRFEEVAWSKYNPRDQL--YLHIGLKPRVRDHYRATKVAFWKHLV 462
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 63 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 122
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 123 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 182
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 183 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 233
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 234 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 265
>BX641059-1|CAE46030.1| 351|Homo sapiens hypothetical protein
protein.
Length = 351
Score = 108 bits (260), Expect = 9e-23
Identities = 69/214 (32%), Positives = 116/214 (54%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 92 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 151
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P + +A+ + + ++
Sbjct: 152 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVEYTSLLADKVGCNVLDTVDM 211
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 212 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 262
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 263 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 294
Score = 96.3 bits (229), Expect = 5e-19
Identities = 66/229 (28%), Positives = 112/229 (48%), Gaps = 19/229 (8%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 61 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 119
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 120 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 179
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 180 ALSSWAVNYQPVEYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 230
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGL 782
F P I+ P++PE L E G +N +++G N EGL
Sbjct: 231 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGL 274
>AF217411-1|AAF71230.1| 828|Homo sapiens neuroligin 3 isoform HNL3
protein.
Length = 828
Score = 108 bits (260), Expect = 9e-23
Identities = 118/465 (25%), Positives = 193/465 (41%), Gaps = 49/465 (10%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 178 GAKPVMVYIHGGSYMEG-TGNMIDGSIPASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 236
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 237 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 296
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 297 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 347
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 348 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 402
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 403 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 458
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDEL 911
+ VT L A S YFY F YH + S K A GDE+
Sbjct: 459 TDHQWVEPSVVTADLHARYGSPTYFYAF----------YHHCQ-SLMKPAWSDAAHGDEV 507
Query: 912 CYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV------ 964
Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 508 PYVFGVPMVGPT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKA 565
Query: 965 --LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFWDNFL 1007
+ W + YLHI KPR+ + + FW + +
Sbjct: 566 NRFEEVAWSKYNPRDQL--YLHIGLKPRVRDHYRATKVAFWKHLV 608
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 209 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 268
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 269 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 328
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 329 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 379
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 380 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 411
Score = 38.3 bits (85), Expect = 0.14
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIH 110
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
>AF217412-1|AAF71231.1| 558|Homo sapiens neuroligin 3 isoform HNL3s
protein.
Length = 558
Score = 107 bits (257), Expect = 2e-22
Identities = 69/214 (32%), Positives = 115/214 (53%), Gaps = 12/214 (5%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
+VI++T+++RVG GF+S GD GN G+ D I AL+W+ NI FGG+P +IT+ G
Sbjct: 229 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 288
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
GA+ V +L S ++GLF AI+QSG+A SS N +P +A+ + + ++
Sbjct: 289 IGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDM 348
Query: 272 ISELGSIAAPKISESELMAIHADDSRKYQVPILANGPVVEHD-HPDAVITKRPEDSFLDV 330
+ L +A ++ E ++ +Y V A GPV++ D PD + FL+
Sbjct: 349 VDCLRQKSAKELVEQDI------QPARYHV---AFGPVIDGDVIPDDPEILMEQGEFLNY 399
Query: 331 EIPIMIGYNTRESIEMMERYLRKPQYLTFADRDF 364
+ IM+G N E ++ +E + ++ D D+
Sbjct: 400 D--IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDY 431
Score = 96.7 bits (230), Expect = 4e-19
Identities = 85/328 (25%), Positives = 144/328 (43%), Gaps = 25/328 (7%)
Query: 558 GSAPVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVVVTISHRLGLLGYLTTEDDVIPGNN 617
G+ PV+V+ + ++ G G++ V+V+T+++R+G+LG+L+T D GN
Sbjct: 198 GAKPVMVYIHGGSYMEG-TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 256
Query: 618 GLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGT 677
GL D + L+W+ +NI FGGD R++V G+ GA+ L S ++GLF +IQSG+
Sbjct: 257 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGS 316
Query: 678 TLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDEFEND 737
L + P + D+ +++ L++ A EL+ +I
Sbjct: 317 ALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDI---------QP 367
Query: 738 QHSTFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQ 793
F P I+ P++PE L E G +N +++G N EGL +
Sbjct: 368 ARYHVAFGPVIDGDVIPDDPEI----LMEQGEFLN-YDIMLGVNQGEGLKFVEGVVDPED 422
Query: 794 LVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG-NVMEYTVYAGD 852
VS + V + Y + G K+ ++ ++F + D + T+ A
Sbjct: 423 GVSGTDFDYSVSNFVDNLYGYPEG----KDTLRETIKFMYTDWADRDNPETRRKTLVALF 478
Query: 853 VLQMYALQKAVT-KLSAELQSNLYFYMF 879
+ VT L A S YFY F
Sbjct: 479 TDHQWVEPSVVTADLHARYGSPTYFYAF 506
Score = 38.3 bits (85), Expect = 0.14
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 22 VETNSGKVEGLEV---KSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKK 78
V T+ GK+ G V I+ Y L +PY PIG RF P+P W+ + NA
Sbjct: 44 VNTHFGKLRGARVPLPSEILGPVDQY--LGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 79 ERKQCAQYY---VP--MRPV------DEVGFC---GSEDCLHLNIH 110
C Q VP M PV D V +EDCL+LN++
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
>AK090997-1|BAC03565.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
3.1.2.14). ).
Length = 469
Score = 106 bits (254), Expect = 5e-22
Identities = 67/192 (34%), Positives = 100/192 (52%), Gaps = 10/192 (5%)
Query: 537 EFGISGSEDCLFINIFTPSLKGSA---PVVVFDYNDNFRTGFNGSLTYAPDFFVEEGVVV 593
+FG+S EDCL++NI+ P+ + PV+V+ F+TG + S+ E V+V
Sbjct: 8 KFGVS--EDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTG-SASIFDGSALAAYEDVLV 64
Query: 594 VTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAA 653
V + +RLG+ G+ TT D PGN +D + L W+Q NI+ FGGD S V++ G GA
Sbjct: 65 VVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAI 124
Query: 654 IAETLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKI---ETDDSEVLL 710
+L+ S AKGLF +++SG + Y K+ + V DSE LL
Sbjct: 125 SVSSLILSPMAKGLFHKAIMESGVAI-IPYLEAHDYEKSEDLQVVAHFCGNNASDSEALL 183
Query: 711 EGLQKVEAGELL 722
L+ + ELL
Sbjct: 184 RCLRTKPSKELL 195
Score = 106 bits (254), Expect = 5e-22
Identities = 58/140 (41%), Positives = 79/140 (56%), Gaps = 2/140 (1%)
Query: 101 SEDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVTISH 160
SEDCL+LNI+ V+V+ F+ T +AS G EDV++V + +
Sbjct: 12 SEDCLYLNIYAPAHADTGSKLP-VLVWFPGGAFK-TGSASIFDGSALAAYEDVLVVVVQY 69
Query: 161 RVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDIL 220
R+G FGF + D PGN KD + AL W+Q NI FGG+P +T+ G+ GA V L
Sbjct: 70 RLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSL 129
Query: 221 LHSPKAKGLFSGAILQSGTA 240
+ SP AKGLF AI++SG A
Sbjct: 130 ILSPMAKGLFHKAIMESGVA 149
>M65261-1|AAA83932.1| 454|Homo sapiens carboxylesterase protein.
Length = 454
Score = 100 bits (240), Expect = 2e-20
Identities = 60/159 (37%), Positives = 87/159 (54%), Gaps = 5/159 (3%)
Query: 102 EDCLHLNIHTXXXXXXXXXXXXVIVFLYNEYFRITYNASKEYGPDFFMKEDVILVTISHR 161
E CL+LNI+T V+V+++ + AS G E+V++VTI +R
Sbjct: 1 EHCLYLNIYTPADLTKKNRLP-VMVWIHGGGLMVGA-ASTYDGLALAAHENVVVVTIQYR 58
Query: 162 VGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILL 221
+G +GF S GD+ GN G D + AL+W+Q NI FGGNP +T+ G+ G V +L+
Sbjct: 59 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 118
Query: 222 HSPKAKGLFSGAILQSGTAYSSMFF---NTKPKDRALAI 257
SP AK LF AI +SG A +S+ + KP +AI
Sbjct: 119 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAI 157
Score = 94.7 bits (225), Expect = 2e-18
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
Query: 544 EDCLFINIFTPS---LKGSAPVVVFDYNDNFRTGFNGSLTY-APDFFVEEGVVVVTISHR 599
E CL++NI+TP+ K PV+V+ + G + TY E VVVVTI +R
Sbjct: 1 EHCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVG--AASTYDGLALAAHENVVVVTIQYR 58
Query: 600 LGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLL 659
LG+ G+ +T D+ GN G D + L+W+QDNI SFGG+ V++ G G L+
Sbjct: 59 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 118
Query: 660 YSKKAKGLFSAVMIQSGTTLEAMYFYR-TPKAKAFEFGRVLKIETDDSEVLLEGLQKVEA 718
S AK LF + +SG L ++ + K A + +T S ++ L++
Sbjct: 119 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAAMVHCLRQKTE 178
Query: 719 GELLRNEIGV 728
ELL + +
Sbjct: 179 EELLETTLKI 188
>BC131699-1|AAI31700.1| 151|Homo sapiens CES4 protein protein.
Length = 151
Score = 95.9 bits (228), Expect = 7e-19
Identities = 45/94 (47%), Positives = 61/94 (64%)
Query: 151 EDVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQ 210
E+V++VTI +R+G +GF S GD+ PGN G D + AL W+Q NI FGGNP +T+ G
Sbjct: 26 ENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAALHWVQDNIASFGGNPGSVTIFGG 85
Query: 211 DGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSM 244
G V +L+ SP AK LF AI +SG A +S+
Sbjct: 86 SAGGESVSVLVLSPLAKNLFHRAISESGVALTSV 119
Score = 84.2 bits (199), Expect = 2e-15
Identities = 41/94 (43%), Positives = 55/94 (58%)
Query: 589 EGVVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGN 648
E VVVVTI +RLG+ G+ +T D+ PGN G D L L W+QDNI SFGG+ V++ G
Sbjct: 26 ENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQLAALHWVQDNIASFGGNPGSVTIFGG 85
Query: 649 RGGAAIAETLLYSKKAKGLFSAVMIQSGTTLEAM 682
G L+ S AK LF + +SG L ++
Sbjct: 86 SAGGESVSVLVLSPLAKNLFHRAISESGVALTSV 119
>AK097538-1|BAC05093.1| 207|Homo sapiens protein ( Homo sapiens
cDNA FLJ40219 fis, clone TESTI2021637, moderately
similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
3.1.1.1). ).
Length = 207
Score = 95.9 bits (228), Expect = 7e-19
Identities = 48/121 (39%), Positives = 70/121 (57%)
Query: 152 DVILVTISHRVGTFGFVSFGDDLLPGNSGVKDVILALKWIQSNINKFGGNPFKITLMGQD 211
DV++VT+ +R+G GF S GD+ PGN G DV+ AL+W+Q NI FGG+ +T+ G
Sbjct: 27 DVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGS 86
Query: 212 GGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFFNTKPKDRALAIAEVLERKLSNSAQF 271
G +++ L+ SP A GLF AI QSG + ++ P A IA L S+ A+
Sbjct: 87 AGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEM 146
Query: 272 I 272
+
Sbjct: 147 V 147
Score = 91.1 bits (216), Expect = 2e-17
Identities = 48/132 (36%), Positives = 70/132 (53%)
Query: 591 VVVVTISHRLGLLGYLTTEDDVIPGNNGLRDFLLGLQWIQDNIKSFGGDASRVSVMGNRG 650
VVVVT+ +RLG+LG+ +T D+ PGN G D + L+W+Q+NI FGGD + V+V G
Sbjct: 28 VVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSA 87
Query: 651 GAAIAETLLYSKKAKGLFSAVMIQSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLL 710
G +I L+ S A GLF + QSG P A + L + ++
Sbjct: 88 GGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMV 147
Query: 711 EGLQKVEAGELL 722
+ LQ+ E EL+
Sbjct: 148 QCLQQKEGEELV 159
>AK094783-1|BAC04422.1| 367|Homo sapiens protein ( Homo sapiens
cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
Length = 367
Score = 73.7 bits (173), Expect = 3e-12
Identities = 69/297 (23%), Positives = 124/297 (41%), Gaps = 24/297 (8%)
Query: 187 ALKWIQSNINKFGGNPFKITLMGQDGGAAMVDILLHSPKAKGLFSGAILQSGTAYSSMFF 246
AL+W+Q NI FGG+P +TL GQ GA + L+ SP A GLF AI QSGTA F
Sbjct: 3 ALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRPFI 62
Query: 247 NTKPKDRALAIAEVLERKLSNSAQFISELGSIAAPKIS--ESELMAIHADDSRKYQVPIL 304
+ P A +A + +++ ++ L +++ K+ +++ + + R + I
Sbjct: 63 TSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIW 122
Query: 305 ANGPVVE----HDHPDAVITKRPEDSFLDVEIPIMIGYNTRESIEMMERYLRKPQYLTFA 360
+ PVV+ D P ++T+ S +P ++G N E ++ ++ P
Sbjct: 123 SMSPVVDGVVIPDDPLVLLTQGKVSS-----VPYLLGVNNLEFNWLLPYIMKFPLNRQAM 177
Query: 361 DRDFLMMFPIRVDYHFELNTNVYYEAIQEIKDFYLEEGYVKISKPGEFMTYMTDINTFYS 420
++ + + ++E D E + + M + D TF
Sbjct: 178 RKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLR--NRMMDIVQDA-TFVY 234
Query: 421 VDYAVRRYLNESSAQIYYYAFDYSGDLNMRKQNILKDAMILEGTWGASIGDELCYLF 477
Y ++ +Y Y F++ + ++ T GA GDE+ +LF
Sbjct: 235 ATLQTAHYHRDAGLPVYLYEFEHHA----------RGIIVKPRTDGADHGDEMYFLF 281
Score = 72.9 bits (171), Expect = 5e-12
Identities = 77/341 (22%), Positives = 149/341 (43%), Gaps = 34/341 (9%)
Query: 623 LLGLQWIQDNIKSFGGDASRVSVMGNRGGAAIAETLLYSKKAKGLFSAVMIQSGTTLEAM 682
+ L+W+Q+NI +FGGD V++ G GA L+ S A GLF + QSGT L
Sbjct: 1 MAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRP 60
Query: 683 YFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLR--NEIGVLDNDEFENDQHS 740
+ P A + + + +++L+ L+ + +++R N++ L + + +
Sbjct: 61 FITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEI 120
Query: 741 TFPFAPTIE----PENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAMPQLVS 796
+ +P ++ P++P ++T G V+ VP L+G N+ E L + + P
Sbjct: 121 IWSMSPVVDGVVIPDDPLVLLT----QGK-VSSVPYLLGVNNLEFNWLLPYIMKFPLNRQ 175
Query: 797 HQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYGNVMEYTVYAGDVLQM 856
+E I + + +N KE ++E Y ++ + H ++ + D++Q
Sbjct: 176 AMRKETITKM-LWSTRTLLN---ITKEQVPLVVEEYLDNVNEHDWKMLRNRMM--DIVQD 229
Query: 857 YALQKAVTKLS-AELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGDELCYLH 915
A + + + L Y+++F H +R K GA GDE+ +L
Sbjct: 230 ATFVYATLQTAHYHRDAGLPVYLYEF--------EHHARGIIVKPRTDGADHGDEMYFL- 280
Query: 916 LCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNP 956
+ L + ++ L +M++ W NFA++ NP
Sbjct: 281 ----FGGPFATGLSMG---KEKALSLQMMKYWANFARTGNP 314
>BC009706-1|AAH09706.1| 150|Homo sapiens CES1 protein protein.
Length = 150
Score = 54.4 bits (125), Expect = 2e-06
Identities = 37/99 (37%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 21 IVETNSGKVEGLEVKSIIKDEKFYSFLSIPYGKAPIGALRFKAPQPHEGWTDVLNAKKER 80
+V+T GKV G V + FL IP+ K P+G LRF PQP E W+ V NA
Sbjct: 26 VVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 85
Query: 81 KQCAQYYVPMRPVDE--------VGFCGSEDCLHLNIHT 111
C Q + + E + SEDCL+LNI+T
Sbjct: 86 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYT 124
Score = 33.5 bits (73), Expect = 4.0
Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 501 LKSMPPVPHKGWEGTYEAYVEKPTCLQ-------FSSRMRNGEE-FGISGSEDCLFINIF 552
L+ PP P + W A P C Q S N +E + SEDCL++NI+
Sbjct: 64 LRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIY 123
Query: 553 TPS 555
TP+
Sbjct: 124 TPA 126
>AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein.
Length = 550
Score = 52.4 bits (120), Expect = 8e-06
Identities = 85/343 (24%), Positives = 133/343 (38%), Gaps = 44/343 (12%)
Query: 674 QSGTTLEAMYFYRTPKAKAFEFGRVLKIETDDSEVLLEGLQKVEAGELLRNEIGVLDNDE 733
QSGT + + P + + +DS +E L++ + EL+ D D
Sbjct: 5 QSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELV-------DQDV 57
Query: 734 FENDQHSTF-PFAP-TIEPENPEAVITNLPENGHIVNDVPVLIGFNSREGLDLTSHFLAM 791
H F P + P++PE ++ + G +N +LIG N EGL
Sbjct: 58 QPARYHIAFGPVVDGDVVPDDPEILM----QQGEFLN-YDMLIGVNQGEGLKFVEDSAES 112
Query: 792 PQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVH-YGNVMEYTVYA 850
VS + V + Y + G K+ ++ ++F + D + G + T+ A
Sbjct: 113 EDGVSASAFDFTVSNFVDNLYGYPEG----KDVLRETIKFMYTDWADRDNGEMRRKTLLA 168
Query: 851 GDV-LQMYALQKAVTKLSAELQSNLYFYMFDFLGEFNENSYHISRFSRYKTENHGATIGD 909
Q A A KL A+ QS +YFY F YH + + + E A GD
Sbjct: 169 LFTDHQWVAPAVATAKLHADYQSPVYFYTF----------YHHCQ-AEGRPEWADAAHGD 217
Query: 910 ELCYLHLCNRIRNTYKQILKLPNVLQDVKLLKKMVRLWTNFAKSRNPT-PSKDDTV---- 964
EL Y+ + T + DV L ++ WTNFAK+ +P P DT
Sbjct: 218 ELPYVFGVPMVGAT--DLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHT 275
Query: 965 ----LNGLIWKPVEKEANVLNYLHITKKPRMDVNPLGDRAKFW 1003
++W + YLHI KPR+ N ++ FW
Sbjct: 276 KPNRFEEVVWSKFNSKEK--QYLHIGLKPRVRDNYRANKVAFW 316
>Z47542-1|CAA87590.1| 368|Homo sapiens SNAP43 protein.
Length = 368
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 782 LDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG 841
LD HF AMP+L+S+++++ I + + + ++ + D+ K D+LE HY
Sbjct: 131 LDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPS-DRVMKLITSDVLEEMLNVHD-HYQ 188
Query: 842 NV 843
N+
Sbjct: 189 NM 190
>U44754-1|AAC50358.1| 368|Homo sapiens PSE-binding factor PTF gamma
subunit protein.
Length = 368
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 782 LDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG 841
LD HF AMP+L+S+++++ I + + + ++ + D+ K D+LE HY
Sbjct: 131 LDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPS-DRVMKLITSDVLEEMLNVHD-HYQ 188
Query: 842 NV 843
N+
Sbjct: 189 NM 190
>BC019038-1|AAH19038.1| 368|Homo sapiens small nuclear RNA
activating complex, polypeptide 1, 43kDa protein.
Length = 368
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 782 LDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG 841
LD HF AMP+L+S+++++ I + + + ++ + D+ K D+LE HY
Sbjct: 131 LDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPS-DRVMKLITSDVLEEMLNVHD-HYQ 188
Query: 842 NV 843
N+
Sbjct: 189 NM 190
>BC014984-1|AAH14984.1| 368|Homo sapiens small nuclear RNA
activating complex, polypeptide 1, 43kDa protein.
Length = 368
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 782 LDLTSHFLAMPQLVSHQIEENIVQFPIRQNYRFVNGDKAYKEAAKDILEFYFEDKSVHYG 841
LD HF AMP+L+S+++++ I + + + ++ + D+ K D+LE HY
Sbjct: 131 LDRAFHFTAMPKLLSYRMKKKIHRAEVTEEFKDPS-DRVMKLITSDVLEEMLNVHD-HYQ 188
Query: 842 NV 843
N+
Sbjct: 189 NM 190
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.138 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 150,699,822
Number of Sequences: 224733
Number of extensions: 6717343
Number of successful extensions: 14356
Number of sequences better than 10.0: 95
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 13732
Number of HSP's gapped (non-prelim): 323
length of query: 1028
length of database: 73,234,838
effective HSP length: 97
effective length of query: 931
effective length of database: 51,435,737
effective search space: 47886671147
effective search space used: 47886671147
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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