GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001962-TA|BGIBMGA001962-PA|IPR000387|Tyrosine specific
protein phosphatase and dual specificity protein phosphatase,
IPR000242|Tyrosine specific protein phosphatase, IPR003595|Protein
tyrosine phosphatase, catalytic region
         (1140 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Z70660-1|CAA94519.1| 1439|Homo sapiens human phosphotyrosine pho...   326   2e-88
X58288-1|CAA41226.1| 1452|Homo sapiens protein-tyrosine phosphat...   326   2e-88
AL590006-4|CAI39438.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL590006-3|CAI39440.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL590006-2|CAI39439.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL451073-4|CAI40500.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL451073-3|CAI40499.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL451073-2|CAI40501.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL357621-5|CAI41223.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL357621-4|CAI41222.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL357621-3|CAI41224.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035594-6|CAI43012.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035594-5|CAI43011.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035594-4|CAI43013.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035470-3|CAI21515.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035470-2|CAI21517.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035470-1|CAI21516.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035465-5|CAI42412.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035465-4|CAI42411.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL035465-3|CAI42410.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AL034349-3|CAI23055.1| 1439|Homo sapiens protein tyrosine phosph...   326   2e-88
AL034349-2|CAI23053.1| 1458|Homo sapiens protein tyrosine phosph...   326   2e-88
AL034349-1|CAI23054.1| 1440|Homo sapiens protein tyrosine phosph...   326   2e-88
AF533875-1|AAO49502.1| 1440|Homo sapiens mutant receptor type pr...   326   2e-88
L77886-1|AAC37599.1| 1440|Homo sapiens protein tyrosine phosphat...   326   4e-88
Z93942-7|CAI19871.1| 1440|Homo sapiens protein tyrosine phosphat...   324   1e-87
Z93942-6|CAI19870.1| 1431|Homo sapiens protein tyrosine phosphat...   324   1e-87
Z93942-4|CAI19865.1| 1463|Homo sapiens protein tyrosine phosphat...   324   1e-87
Z93942-3|CAI19868.1| 1450|Homo sapiens protein tyrosine phosphat...   324   1e-87
Z93942-2|CAI19867.1| 1444|Homo sapiens protein tyrosine phosphat...   324   1e-87
Z93942-1|CAI19866.1| 1441|Homo sapiens protein tyrosine phosphat...   324   1e-87
AL136461-7|CAH72559.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL136461-6|CAH72558.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL136461-4|CAH72553.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL136461-3|CAH72556.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL136461-2|CAH72555.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL136461-1|CAH72554.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-7|CAI23316.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-6|CAI23315.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-4|CAI23310.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-3|CAI23313.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-2|CAI23312.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL121763-1|CAI23311.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-8|CAI19250.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-7|CAI19256.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-6|CAI19255.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-4|CAI19253.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-3|CAI19252.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL049812-2|CAI19251.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-7|CAI22915.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-6|CAI22914.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-4|CAI22909.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-3|CAI22912.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-2|CAI22911.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL035459-1|CAI22910.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-7|CAI19876.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-6|CAI19882.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-4|CAI19877.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-3|CAI19880.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-2|CAI19879.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL031656-1|CAI19878.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-7|CAI22495.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-6|CAI22494.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-4|CAI22489.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-3|CAI22492.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-2|CAI22491.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL024473-1|CAI22490.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-7|CAI20443.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-6|CAI20442.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-4|CAI20437.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-3|CAI20440.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-2|CAI20439.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL022239-1|CAI20438.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-7|CAI19987.1| 1440|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-6|CAI19986.1| 1431|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-4|CAI19981.1| 1463|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-3|CAI19984.1| 1450|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-2|CAI19983.1| 1444|Homo sapiens protein tyrosine phosph...   324   1e-87
AL021395-1|CAI19982.1| 1441|Homo sapiens protein tyrosine phosph...   324   1e-87
AF043644-1|AAD09421.2| 1463|Homo sapiens receptor protein tyrosi...   324   1e-87
AB006621-1|BAA22952.2| 1471|Homo sapiens KIAA0283 protein.            324   1e-87
BC051651-1|AAH51651.1| 1390|Homo sapiens PTPRM protein protein.       320   2e-86
U73727-1|AAB51343.1| 1436|Homo sapiens receptor protein tyrosine...   316   2e-85
AL645859-2|CAH72393.1| 1436|Homo sapiens protein tyrosine phosph...   316   2e-85
AL645859-1|CAH72394.1| 1446|Homo sapiens protein tyrosine phosph...   316   2e-85
AL590729-6|CAI14332.1| 1446|Homo sapiens protein tyrosine phosph...   316   2e-85
AL590729-5|CAI14331.1| 1436|Homo sapiens protein tyrosine phosph...   316   2e-85
AL049570-2|CAI20947.1| 1446|Homo sapiens protein tyrosine phosph...   316   2e-85
AL049570-1|CAI20946.1| 1436|Homo sapiens protein tyrosine phosph...   316   2e-85
AB208855-1|BAD92092.1| 1243|Homo sapiens Receptor protein tyrosi...   316   2e-85
U71075-1|AAC51938.1| 1439|Homo sapiens protein tyrosine phosphat...   314   1e-84
U60289-1|AAB07074.1| 1436|Homo sapiens receptor protein tyrosine...   313   2e-84
X97198-1|CAA65832.1| 1430|Homo sapiens receptor phosphatase PCP-...   310   1e-83
Z93942-5|CAI19869.1| 1451|Homo sapiens protein tyrosine phosphat...   304   1e-81
AL136461-5|CAH72557.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL121763-5|CAI23314.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL049812-5|CAI19254.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL035459-5|CAI22913.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL031656-5|CAI19881.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL024473-5|CAI22493.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL022239-5|CAI20441.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
AL021395-5|CAI19985.1| 1451|Homo sapiens protein tyrosine phosph...   304   1e-81
X95712-1|CAA65016.1| 1442|Homo sapiens FMI protein protein.           301   7e-81
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph...   264   1e-69
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat...   263   2e-69
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph...   263   2e-69
AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]...   263   3e-69
X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphat...   261   9e-69
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat...   261   9e-69
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.       261   9e-69
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.       261   9e-69
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.       261   9e-69
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.       261   9e-69
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph...   261   9e-69
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph...   261   9e-69
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.      261   1e-68
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.              261   1e-68
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -...   253   2e-66
BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein pr...   253   2e-66
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp...   253   2e-66
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph...   253   2e-66
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.                 253   2e-66
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr...   253   2e-66
AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine phosph...   252   7e-66
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph...   251   9e-66
X54130-1|CAA38065.1|  793|Homo sapiens protein-tyrosine phosphat...   238   9e-62
X53364-1|CAA37447.1|  793|Homo sapiens tyrosine phosphatase prec...   238   9e-62
M34668-1|AAA36528.1|  802|Homo sapiens protein ( Human protein t...   238   9e-62
BC027308-1|AAH27308.1|  793|Homo sapiens protein tyrosine phosph...   238   9e-62
AL121905-6|CAC10336.1|  802|Homo sapiens protein tyrosine phosph...   238   9e-62
AL121905-5|CAC10337.1|  793|Homo sapiens protein tyrosine phosph...   238   9e-62
AB209702-1|BAD92939.1|  651|Homo sapiens protein tyrosine phosph...   238   9e-62
AJ315969-1|CAC86583.1|  642|Homo sapiens tyrosine phosphatase ep...   237   2e-61
X54134-1|CAA38069.1|  700|Homo sapiens protein-tyrosine phosphat...   235   7e-61
BC050062-1|AAH50062.1|  700|Homo sapiens PTPRE protein protein.       235   7e-61
AL390236-6|CAH73174.1|  642|Homo sapiens protein tyrosine phosph...   235   7e-61
AL390236-5|CAH73173.1|  700|Homo sapiens protein tyrosine phosph...   235   7e-61
X54890-1|CAA38662.1|  793|Homo sapiens protein-tyrosine phosphat...   233   3e-60
U46116-1|AAC50439.1| 1445|Homo sapiens receptor tyrosine phospha...   222   5e-57
X54132-1|CAA38067.1|  610|Homo sapiens protein-tyrosine phosphat...   222   7e-57
L09247-1|AAA60224.1| 1445|Homo sapiens receptor-type protein tyr...   222   7e-57
AB209871-1|BAD93108.1| 1530|Homo sapiens protein tyrosine phosph...   222   7e-57
M93426-1|AAA60225.1| 2314|Homo sapiens protein tyrosine phosphat...   221   1e-56
AC006020-1|AAF03527.1| 1648|Homo sapiens WUGSC:H_DJ1049N15.1 pro...   221   1e-56
Y00062-1|CAA68269.1| 1143|Homo sapiens protein ( Human mRNA for ...   209   4e-53
M23492-1|AAD15273.2| 1114|Homo sapiens T200 leukocyte common ant...   209   4e-53
AL355988-3|CAI19379.1| 1145|Homo sapiens protein tyrosine phosph...   209   4e-53
AL355988-2|CAI19378.1| 1306|Homo sapiens protein tyrosine phosph...   209   4e-53
AL157402-4|CAI15640.1| 1145|Homo sapiens protein tyrosine phosph...   209   4e-53
AL157402-3|CAI15641.1| 1306|Homo sapiens protein tyrosine phosph...   209   4e-53
Y00638-1|CAA68669.1| 1304|Homo sapiens protein ( Human mRNA for ...   205   6e-52
X54135-1|CAA38070.1|  613|Homo sapiens protein-tyrosine phosphat...   171   2e-41
BC040543-1|AAH40543.1|  279|Homo sapiens PTPRM protein protein.       152   8e-36
BX648771-1|CAE46198.1| 1956|Homo sapiens hypothetical protein pr...   134   1e-30
AJ430580-1|CAD23182.1|  536|Homo sapiens tyrosine phosphatase ep...   134   1e-30
X54131-1|CAA38066.1| 1997|Homo sapiens protein-tyrosine phosphat...   134   2e-30
BC113463-1|AAI13464.1| 1997|Homo sapiens protein tyrosine phosph...   134   2e-30
BC101679-1|AAI01680.1| 1997|Homo sapiens protein tyrosine phosph...   134   2e-30
U10886-1|AAB36687.1| 1337|Homo sapiens density enhanced phosphat...   132   5e-30
D37781-1|BAA07035.1| 1337|Homo sapiens protein-tyrosine phosphat...   132   5e-30
AF387844-1|AAM69432.1| 1305|Homo sapiens protein tyrosine phosph...   132   5e-30
Z48541-1|CAA88425.1| 1216|Homo sapiens protein tyrosine phosphat...   132   9e-30
U20489-1|AAA82892.1| 1188|Homo sapiens glomerular epithelial pro...   132   9e-30
BC126203-1|AAI26204.1| 1216|Homo sapiens protein tyrosine phosph...   132   9e-30
BC126201-1|AAI26202.1| 1216|Homo sapiens protein tyrosine phosph...   132   9e-30
AF187044-1|AAF04087.1|  377|Homo sapiens protein tyrosine phosph...   132   9e-30
AF187043-1|AAF04086.1|  405|Homo sapiens protein tyrosine phosph...   132   9e-30
AF187042-1|AAF04085.1|  377|Homo sapiens protein tyrosine phosph...   132   9e-30
AF152378-1|AAD55680.1|  405|Homo sapiens protein tyrosine phosph...   132   9e-30
BC111715-1|AAI11716.1|  937|Homo sapiens PTPRH protein protein.       128   8e-29
D15049-1|BAA03645.2| 1117|Homo sapiens protein tyrosine phosphat...   128   1e-28
BC111716-1|AAI11717.1| 1115|Homo sapiens protein tyrosine phosph...   128   1e-28
AF275150-1|AAF91411.1| 1115|Homo sapiens transmembrane-type prot...   128   1e-28
X70766-1|CAA50045.1|  593|Homo sapiens protein-tyrosine phosphat...   126   5e-28
L07527-1|AAA17022.1|  593|Homo sapiens protein-tyrosine phosphat...   126   5e-28
L03535-1|AAA36611.1|  593|Homo sapiens phosphotyrosyl-protein ph...   126   5e-28
D13540-1|BAA02740.2|  593|Homo sapiens protein-tyrosine phosphat...   126   5e-28
EF064714-1|ABK41897.1|  807|Homo sapiens protein tyrosine phosph...   124   2e-27
AL137856-2|CAI19068.1|  807|Homo sapiens protein tyrosine phosph...   124   2e-27
AF150732-1|AAF67472.1|  799|Homo sapiens protein tyrosine phosph...   123   4e-27
M93425-1|AAA36529.1|  780|Homo sapiens protein tyrosine phosphat...   122   6e-27
BC050008-1|AAH50008.2|  780|Homo sapiens protein tyrosine phosph...   122   6e-27
AC006451-1|AAQ96881.1|  780|Homo sapiens unknown protein.             122   6e-27
AB209524-1|BAD92761.1|  807|Homo sapiens protein tyrosine phosph...   122   6e-27
D13380-1|BAA02648.1|  780|Homo sapiens protein tyrosine phosphat...   122   7e-27
M25393-1|AAA65997.1|  415|Homo sapiens protein tyrosine phosphat...   120   2e-26
BC016727-1|AAH16727.1|  353|Homo sapiens protein tyrosine phosph...   120   2e-26
BC008244-1|AAH08244.1|  387|Homo sapiens protein tyrosine phosph...   120   2e-26
AB209569-1|BAD92806.1|  392|Homo sapiens protein tyrosine phosph...   120   2e-26
D11327-1|BAA01946.1|  360|Homo sapiens protein-tyrosine phosphat...   120   3e-26
AF001847-1|AAD00905.1|  692|Homo sapiens lymphoid phosphatase Ly...   120   4e-26
AF001846-1|AAD00904.1|  808|Homo sapiens lymphoid phosphatase Ly...   120   4e-26
BT009848-1|AAP88850.1|  360|Homo sapiens protein tyrosine phosph...   119   7e-26
BC001746-1|AAH01746.2|  399|Homo sapiens protein tyrosine phosph...   119   7e-26
AL592300-4|CAI13109.1|  465|Homo sapiens protein tyrosine phosph...   119   7e-26
AL592300-3|CAI13108.1|  399|Homo sapiens protein tyrosine phosph...   119   7e-26
Y08569-1|CAA69880.1| 1015|Homo sapiens Islet Cell Autoantigen Re...   118   9e-26
U81561-1|AAB68603.1|  998|Homo sapiens protein tyrosine phosphat...   118   9e-26
U66702-1|AAC50742.1| 1015|Homo sapiens phogrin protein.               118   9e-26
U65065-1|AAC51643.1|  986|Homo sapiens tyrosine phosphatase IA-2...   118   9e-26
BC034040-1|AAH34040.1|  986|Homo sapiens protein tyrosine phosph...   118   9e-26
AF007555-1|AAB63600.1| 1015|Homo sapiens IAR/receptor-like prote...   118   9e-26
AB002385-1|BAA20841.2| 1042|Homo sapiens KIAA0387 protein.            118   9e-26
M64322-1|AAA59531.1|  339|Homo sapiens protein tyrosine phosphat...   118   1e-25
M33689-1|AAA60157.1|  435|Homo sapiens non-receptor tyrosine pho...   118   2e-25
M31724-1|AAA60223.1|  435|Homo sapiens PTPN1 protein.                 118   2e-25
BT006752-1|AAP35398.1|  435|Homo sapiens protein tyrosine phosph...   118   2e-25
BC018164-1|AAH18164.1|  435|Homo sapiens protein tyrosine phosph...   118   2e-25
BC015660-1|AAH15660.1|  435|Homo sapiens protein tyrosine phosph...   118   2e-25
AL133230-1|CAC00618.2|  435|Homo sapiens protein tyrosine phosph...   118   2e-25
AL034429-1|CAI23215.1|  435|Homo sapiens protein tyrosine phosph...   118   2e-25
Z79693-1|CAB01957.1|  670|Homo sapiens protein-tyrosine phosphat...   117   2e-25
X82635-1|CAA57957.1|  382|Homo sapiens protein-tyrosine-phosphat...   117   2e-25
U77917-1|AAB54007.1|  412|Homo sapiens Ch-1PTPase gamma minus fo...   117   3e-25
U77916-1|AAB54006.1|  451|Homo sapiens Ch-1PTPase delta form pro...   117   3e-25
U42361-1|AAD09447.1|  657|Homo sapiens protein tyrosine phosphat...   117   3e-25
D64053-1|BAA10930.1|  657|Homo sapiens tyrosine phosphatase prot...   117   3e-25
BX571751-1|CAE11876.1|  412|Homo sapiens hypothetical protein pr...   117   3e-25
BC122866-1|AAI22867.1|  412|Homo sapiens PTPRR protein protein.       117   3e-25
BC110900-1|AAI10901.1|  412|Homo sapiens PTPRR protein protein.       117   3e-25
AF263029-1|AAG47642.1|  657|Homo sapiens protein tyrosine phosph...   117   3e-25
BC119777-1|AAI19778.1|  412|Homo sapiens PTPRR protein protein.       115   8e-25
X62055-1|CAA43982.1|  597|Homo sapiens protein-tyrosine  phospha...   113   3e-24
U47924-18|AAB51323.1|  595|Homo sapiens protein tyrosine phospha...   113   3e-24
U47924-17|AAB51322.1|  556|Homo sapiens protein tyrosine phospha...   113   3e-24
U15528-2|AAA82880.1|  595|Homo sapiens protein tyrosine phosphat...   113   3e-24
U15528-1|AAA82879.1|  556|Homo sapiens protein tyrosine phosphat...   113   3e-24
M77273-1|AAA36610.1|  595|Homo sapiens tyrosine phosphatase prot...   113   3e-24
M74903-1|AAA35963.1|  595|Homo sapiens hematopoietic cell phopha...   113   3e-24
BT007390-1|AAP36054.1|  597|Homo sapiens protein tyrosine phosph...   113   3e-24
BC007667-1|AAH07667.1|  597|Homo sapiens protein tyrosine phosph...   113   3e-24
BC002523-1|AAH02523.1|  597|Homo sapiens protein tyrosine phosph...   113   3e-24
AF178946-1|AAD53317.1|  624|Homo sapiens 70 kDa SHP-1L protein p...   113   3e-24
AB079851-2|BAC81775.1|  595|Homo sapiens protein tyrosine phosph...   113   3e-24
AB079851-1|BAC81774.1|  597|Homo sapiens protein tyrosine phosph...   113   3e-24
AK223629-1|BAD97349.1|  595|Homo sapiens protein tyrosine phosph...   113   3e-24
X62899-1|CAA44688.2|  591|Homo sapiens Islet Cell Antigen 512 pr...   111   1e-23
L18983-1|AAA90974.1|  979|Homo sapiens tyrosine phosphatase prot...   111   1e-23
BT006975-1|AAP35621.1|  591|Homo sapiens protein tyrosine phosph...   111   1e-23
BC070053-1|AAH70053.1|  950|Homo sapiens PTPRN protein protein.       111   1e-23
BC007713-1|AAH07713.2|  811|Homo sapiens PTPRN protein protein.       111   1e-23
AC114803-2|AAY24038.1|  979|Homo sapiens unknown protein.             111   1e-23
AL050040-1|CAB43248.1|  398|Homo sapiens hypothetical protein pr...   110   3e-23
X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphat...   109   6e-23
X79676-1|CAA56124.1| 1267|Homo sapiens tyrosine phosphatase prot...   109   6e-23
U12128-1|AAB60339.1| 2490|Homo sapiens protein tyrosine phosphat...   109   6e-23
D21211-1|BAA04752.1| 2294|Homo sapiens protein tyrosine phosphat...   109   6e-23
D21210-1|BAA04751.1| 2466|Homo sapiens protein tyrosine phosphat...   109   6e-23
D21209-1|BAA04750.1| 2485|Homo sapiens protein tyrosine phosphat...   109   6e-23
BX005072-1|CAI23640.1|  339|Homo sapiens protein tyrosine phosph...   109   6e-23
AY704152-1|AAW28791.1|  339|Homo sapiens non-receptor protein ty...   109   6e-23
AY704150-1|AAW28789.1|  392|Homo sapiens non-receptor protein ty...   109   6e-23
AY704146-1|AAW28785.1|  420|Homo sapiens non-receptor protein ty...   109   6e-23
AY704143-1|AAW28782.1|  228|Homo sapiens non-receptor protein ty...   109   6e-23
AY704141-1|AAW28780.1|  411|Homo sapiens non-receptor protein ty...   109   6e-23
AL672108-3|CAI12201.1|  398|Homo sapiens protein tyrosine phosph...   109   6e-23
AL450334-4|CAI15686.1|  398|Homo sapiens protein tyrosine phosph...   109   6e-23
AL358791-1|CAI14088.1|  339|Homo sapiens protein tyrosine phosph...   109   6e-23
AC105413-1|AAY40972.1| 1305|Homo sapiens unknown protein.             109   6e-23
AB208904-1|BAD92141.1| 2434|Homo sapiens protein tyrosine phosph...   109   6e-23
M83738-1|AAA60226.1|  593|Homo sapiens protein-tyrosine phosphat...   107   3e-22
BT007405-1|AAP36073.1|  593|Homo sapiens protein tyrosine phosph...   107   3e-22
BC071574-1|AAH71574.1|  583|Homo sapiens PTPN9 protein protein.       107   3e-22
BC010863-1|AAH10863.1|  593|Homo sapiens protein tyrosine phosph...   107   3e-22
U27831-1|AAA87555.1|  537|Homo sapiens striatum-enriched phospha...   103   3e-21
BC064807-1|AAH64807.1|  565|Homo sapiens protein tyrosine phosph...   103   4e-21
BC046435-1|AAH46435.1|  201|Homo sapiens PTPN5 protein protein.       103   4e-21
AK090923-1|BAC03548.1|  565|Homo sapiens protein ( Homo sapiens ...   103   4e-21
BC039897-1|AAH39897.1|  596|Homo sapiens PTPN5 protein protein.       100   3e-20
BC071670-1|AAH71670.1|  752|Homo sapiens PTPN22 protein protein.       99   4e-20
AL137856-3|CAI19069.1|  348|Homo sapiens protein tyrosine phosph...    99   4e-20
AF394064-1|AAM69538.1|  293|Homo sapiens dual specificity phosph...    97   2e-19
X82676-1|CAA57993.1| 1187|Homo sapiens tyrosine phosphatase prot...    97   3e-19
BC104803-1|AAI04804.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
BC101754-1|AAI01755.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
AL929236-1|CAH70919.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
AL603838-1|CAH72982.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
AL592216-1|CAH73479.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
AL445305-1|CAH73027.1| 1187|Homo sapiens protein tyrosine phosph...    97   3e-19
M68941-1|AAA36530.1|  926|Homo sapiens protein-tyrosine phophata...    96   6e-19
BC010674-1|AAH10674.1|  926|Homo sapiens protein tyrosine phosph...    96   6e-19
AC016691-1|AAX88858.1|  266|Homo sapiens unknown protein.              96   6e-19
X79510-1|CAA56042.1| 1174|Homo sapiens protein-tyrosine-phosphat...    93   7e-18
AL353786-2|CAD19000.1| 1024|Homo sapiens dJ1175B15.2 (protein ty...    93   7e-18
X79568-1|CAA56105.1|  458|Homo sapiens protein-tyrosine-phosphat...    92   1e-17
AC132479-3|AAY24077.1|  460|Homo sapiens unknown protein.              92   1e-17
M64572-1|AAA35647.1|  913|Homo sapiens protein-tyrosine phosphat...    91   2e-17
BC126117-1|AAI26118.1|  913|Homo sapiens protein tyrosine phosph...    91   2e-17
BC033716-1|AAH33716.1|  292|Homo sapiens Unknown (protein for IM...    91   2e-17
AL450025-1|CAH73252.1|  913|Homo sapiens protein tyrosine phosph...    91   2e-17
AL359963-4|CAH71094.1|  913|Homo sapiens protein tyrosine phosph...    91   2e-17
AL162733-1|CAH73386.1|  913|Homo sapiens protein tyrosine phosph...    91   2e-17
S39392-1|AAB22439.2|  703|Homo sapiens protein tyrosine phosphat...    90   4e-17
BT007106-1|AAP35770.1|  460|Homo sapiens protein tyrosine phosph...    89   8e-17
BC008692-1|AAH08692.1|  460|Homo sapiens PTPN11 protein protein.       89   8e-17
AY704158-1|AAW28797.1|  179|Homo sapiens non-receptor protein ty...    86   8e-16
AL603966-4|CAI12337.1|  265|Homo sapiens protein tyrosine phosph...    83   7e-15
BC014239-1|AAH14239.1|  756|Homo sapiens PTPRC protein protein.        80   4e-14
AL355988-1|CAI19377.1|  753|Homo sapiens protein tyrosine phosph...    79   1e-13
AL157402-2|CAI15639.1|  753|Homo sapiens protein tyrosine phosph...    79   1e-13
BT009758-1|AAP88760.1|  577|Homo sapiens protein tyrosine phosph...    77   4e-13
BC089042-1|AAH89042.1| 1636|Homo sapiens protein tyrosine phosph...    77   4e-13
BC027711-1|AAH27711.2| 1320|Homo sapiens PTPN23 protein protein.       77   4e-13
BC004881-1|AAH04881.2|  619|Homo sapiens PTPN23 protein protein.       77   4e-13
AL110210-1|CAB53676.1|  990|Homo sapiens hypothetical protein pr...    77   4e-13
AF290614-1|AAK28025.1| 1636|Homo sapiens protein tyrosine phosph...    77   4e-13
AB025194-1|BAB19280.1| 1636|Homo sapiens protein tyrosine phosph...    77   4e-13
AY704153-1|AAW28792.1|  197|Homo sapiens non-receptor protein ty...    65   1e-09
AY704142-1|AAW28781.1|  269|Homo sapiens non-receptor protein ty...    65   1e-09
BC017785-1|AAH17785.1|  179|Homo sapiens PTPN22 protein protein.       65   2e-09
AF169351-1|AAD50277.1|  134|Homo sapiens protein tyrosine phosph...    63   6e-09
M33684-1|AAA60158.1|  271|Homo sapiens non-receptor tyrosine pho...    61   2e-08
S69184-1|AAB30047.2|   78|Homo sapiens protein tyrosine phosphat...    58   2e-07
BC052800-1|AAH52800.1|  351|Homo sapiens PTPN18 protein protein.       58   2e-07
BC041562-1|AAH41562.1|  372|Homo sapiens Similar to protein tyro...    58   2e-07
BC024280-1|AAH24280.1|  372|Homo sapiens Similar to protein tyro...    58   2e-07
S78080-1|AAB21146.2|   87|Homo sapiens protein-tyrosine phosphat...    56   7e-07
AB209368-1|BAD92605.1|  824|Homo sapiens protein tyrosine phosph...    56   7e-07
BC092469-1|AAH92469.1|  254|Homo sapiens PTPRR protein protein.        53   5e-06
DQ104439-1|AAZ20185.1|  839|Homo sapiens tyrosine phosphatase pr...    53   7e-06
AB040904-1|BAA95995.2| 1421|Homo sapiens KIAA1471 protein protein.     48   3e-04
S78088-1|AAB21148.2|   91|Homo sapiens protein-tyrosine phosphat...    44   0.003
AF169350-1|AAD50276.1|  143|Homo sapiens protein tyrosine phosph...    44   0.004
U69700-1|AAB09079.1|   84|Homo sapiens protein tyrosine phosphat...    42   0.013
AF227899-1|AAF36964.1|  873|Homo sapiens breast carcinoma-associ...    41   0.022
AF214114-1|AAF28341.2| 1226|Homo sapiens retinoblastoma-binding ...    41   0.022
AF230533-1|AAG36793.1|  621|Homo sapiens nuclear receptor coacti...    41   0.029
BC130418-1|AAI30419.1| 1153|Homo sapiens ARID4B protein protein.       40   0.067
AL391994-7|CAI13752.1| 1071|Homo sapiens AT rich interactive dom...    40   0.067
AL391994-6|CAI13751.1| 1226|Homo sapiens AT rich interactive dom...    40   0.067
AL391994-2|CAI13747.1| 1310|Homo sapiens AT rich interactive dom...    40   0.067
AL133418-7|CAI22963.1| 1071|Homo sapiens AT rich interactive dom...    40   0.067
AL133418-6|CAI22962.1| 1226|Homo sapiens AT rich interactive dom...    40   0.067
AL133418-5|CAI22961.1| 1310|Homo sapiens AT rich interactive dom...    40   0.067
AK023144-1|BAB14428.1|  459|Homo sapiens protein ( Homo sapiens ...    40   0.067
AF208045-1|AAF23433.3| 1213|Homo sapiens breast cancer-associate...    40   0.067
AF201422-1|AAF21439.1| 2296|Homo sapiens splicing coactivator su...    40   0.067
AF083249-1|AAD41239.1|  748|Homo sapiens Rb binding protein homo...    40   0.067
AC004493-2|AAC08453.1| 1791|Homo sapiens KIAA0324 protein.             40   0.067
AB210032-1|BAE06114.1| 1325|Homo sapiens ARID4B variant protein ...    40   0.067
AB016092-1|BAA83718.1| 2752|Homo sapiens RNA binding protein pro...    40   0.067
AB016091-1|BAA83717.1| 1275|Homo sapiens RNA binding protein pro...    40   0.067
AB002322-1|BAA20782.3| 2800|Homo sapiens KIAA0324 protein protein.     40   0.067
AF479418-1|AAO14651.1| 1227|Homo sapiens FOE protein.                  39   0.089
AY220790-1|AAO63590.1| 1312|Homo sapiens SIN3A-associated protei...    38   0.16 
AK092426-1|BAC03887.1|  258|Homo sapiens protein ( Homo sapiens ...    38   0.21 
AF094508-1|AAD16120.1|  788|Homo sapiens dentin phosphoryn protein.    38   0.27 
AL391994-1|CAI13746.1|  927|Homo sapiens AT rich interactive dom...    36   0.63 
AL162458-1|CAH74052.1|  579|Homo sapiens nuclear receptor coacti...    36   0.63 
AL133418-1|CAI22958.1|  927|Homo sapiens AT rich interactive dom...    36   0.63 
AL035662-2|CAI42972.1|  579|Homo sapiens nuclear receptor coacti...    36   0.63 
AF470686-1|AAO33457.1|  579|Homo sapiens estrogen receptor coact...    36   0.63 
AB030181-1|BAA89794.1|  803|Homo sapiens RBP1-like protein protein.    36   0.63 
AY704148-1|AAW28787.1|  206|Homo sapiens non-receptor protein ty...    36   0.83 
D87450-1|BAA13391.1| 1287|Homo sapiens KIAA0261 protein.               35   1.9  
AL844892-1|CAH73376.1| 1275|Homo sapiens wings apart-like homolo...    35   1.9  
AL731569-1|CAI16708.1| 1275|Homo sapiens wings apart-like homolo...    35   1.9  
AL133561-1|CAB63715.1|  580|Homo sapiens hypothetical protein pr...    35   1.9  
AB065003-1|BAC78631.1| 1190|Homo sapiens mammalian homolog of wi...    35   1.9  
BC117319-1|AAI17320.1|  257|Homo sapiens TPRXL protein protein.        34   2.5  
AK128053-1|BAC87252.1|  654|Homo sapiens protein ( Homo sapiens ...    34   2.5  
AF163151-1|AAF42472.1| 1253|Homo sapiens dentin sialophosphoprot...    34   3.3  
AC005757-1|AAC62258.1|  540|Homo sapiens R32611_1 protein.             34   3.3  
AB084087-1|BAC67014.1| 1422|Homo sapiens Formactin2 protein.           34   3.3  
Z83844-7|CAI20371.1| 2193|Homo sapiens protein ( Human DNA seque...    33   4.4  
DQ278603-1|ABB77204.1| 2266|Homo sapiens trio-associated repeat ...    33   4.4  
DQ228005-1|ABB59561.1| 2365|Homo sapiens TRIOBP isoform 6 protein.     33   4.4  
DQ228004-1|ABB59560.1| 1144|Homo sapiens TRIOBP isoform 4 protein.     33   4.4  
DQ228003-1|ABB59559.1| 2193|Homo sapiens TRIOBP isoform 3 protein.     33   4.4  
BC070050-1|AAH70050.1| 1022|Homo sapiens SRRM2 protein protein.        33   7.7  
BC038976-1|AAH38976.2|  475|Homo sapiens Rho GTPase activating p...    33   7.7  
BC016701-1|AAH16701.1|  475|Homo sapiens Rho GTPase activating p...    33   7.7  
AY219338-1|AAO34684.1|  475|Homo sapiens ARHGAP15 protein.             33   7.7  
AB016088-1|BAA83714.1|  956|Homo sapiens RNA binding protein pro...    33   7.7  
AB016087-1|BAA83713.1| 1262|Homo sapiens RNA binding protein pro...    33   7.7  

>Z70660-1|CAA94519.1| 1439|Homo sapiens human phosphotyrosine
            phosphatase kappa protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>X58288-1|CAA41226.1| 1452|Homo sapiens protein-tyrosine phosphatase
            protein.
          Length = 1452

 Score =  326 bits (802), Expect = 2e-88
 Identities = 181/502 (36%), Positives = 281/502 (55%), Gaps = 31/502 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP ++T+ DFWRM+W E  A+I+M+T   +  +V C +YWP   +  E Y 
Sbjct: 964  RPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYK 1020

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            DI V +++ E LA + IRTF +   EK  V E R I QFH+T W  H  P+ +  LL F 
Sbjct: 1021 DIKVTLIETELLAEYVIRTFAV---EKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFV 1077

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G ++ ID  L++AE E   D++ C+++LR
Sbjct: 1078 RQVKSKSP------PSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELR 1131

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  P S++       ++ DP T  ++ ++E++
Sbjct: 1132 SRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFR 1191

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TP   + DC+      N EKNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1192 TLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGES-SNYINAALMDS 1250

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CVPPKNSQQYPPFWPE-GRHSKK 402
            Y +P  +I T+ PL  T  +FW LV DY C +VV+L  V P  +Q  P +WPE G H  +
Sbjct: 1251 YKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVH--R 1306

Query: 403  YGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKV 462
            +GP+  ++ VS +   +I + IFRI           A  +   + VQ FQ   WPM    
Sbjct: 1307 HGPI-QVEFVSADLEEDIISRIFRIYN--------AARPQDGYRMVQQFQFLGWPMYRDT 1357

Query: 463  PSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDV 520
            P S  S ++L+  V++W++  +   GP  V   +G  R+G +CA +   E +     VDV
Sbjct: 1358 PVSKRSFLKLIRQVDKWQEEYNGGEGPTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDV 1417

Query: 521  FQAVKTVRRHRPQLVENMCELK 542
            F AVKT+R ++P +V+ + + K
Sbjct: 1418 FHAVKTLRNNKPNMVDLLDQYK 1439



 Score =  109 bits (263), Expect = 4e-23
 Identities = 67/212 (31%), Positives = 99/212 (46%), Gaps = 8/212 (3%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR++      ++VML         +C QYWP N   
Sbjct: 1248 MDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGV- 1304

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHT-CPFSNA 159
               +G I V  V  +   +   R FR+Y   +      R + QF +  W  +   P S  
Sbjct: 1305 -HRHGPIQVEFVSADLEEDIISRIFRIYNAARPQD-GYRMVQQFQFLGWPMYRDTPVSKR 1362

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
               F              N   GP VVHC +GGGRSG + AI    E+   + + DVF  
Sbjct: 1363 --SFLKLIRQVDKWQEEYNGGEGPTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHA 1420

Query: 220  LKKLRESRKGLIENEEQYKFVYDTLEEHVVCG 251
            +K LR ++  +++  +QYKF Y+   E++  G
Sbjct: 1421 VKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG 1452



 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 61/235 (25%), Positives = 111/235 (47%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            + +NR KNR   ++  D+ R  L + +G++ +DYIN  ++DGY +P  YIAT+ P+  T 
Sbjct: 920  KDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETI 979

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +V+    A+++++  +      +   +WP+     K   V  I+      Y  I+
Sbjct: 980  YDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYV-IR 1038

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
            T  F + K+         GV    + ++ F  T WP  H VP     L+  +  V+  + 
Sbjct: 1039 T--FAVEKR---------GVH-EIREIRQFHFTGWP-DHGVPYHATGLLGFVRQVKS-KS 1084

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G +   +  ++   + G VD++  V+ +R  R  +V+
Sbjct: 1085 PPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQ 1139


>AL590006-4|CAI39438.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL590006-3|CAI39440.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL590006-2|CAI39439.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL451073-4|CAI40500.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL451073-3|CAI40499.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL451073-2|CAI40501.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL357621-5|CAI41223.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL357621-4|CAI41222.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL357621-3|CAI41224.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL035594-6|CAI43012.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL035594-5|CAI43011.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL035594-4|CAI43013.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL035470-3|CAI21515.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL035470-2|CAI21517.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL035470-1|CAI21516.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL035465-5|CAI42412.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL035465-4|CAI42411.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL035465-3|CAI42410.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AL034349-3|CAI23055.1| 1439|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1439

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 951  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1007

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1008 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1064

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1065 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1118

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1119 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1178

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1179 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1237

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1238 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1295

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1296 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1346

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1347 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1406

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1407 AVKTLRNSKPNMVE 1420



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1235 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1290

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1291 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1345

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1346 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1405

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1406 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1436



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 907  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 966

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 967  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1023

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1024 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1071

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1072 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1126


>AL034349-2|CAI23053.1| 1458|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1458

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 970  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1026

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1027 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1083

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1084 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1137

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1138 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1197

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1198 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1256

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1257 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1314

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1315 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1365

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1366 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1425

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1426 AVKTLRNSKPNMVE 1439



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1254 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1309

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1310 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1364

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1365 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1424

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1425 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1455



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEW 356
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++D      GY +P  YIAT+ 
Sbjct: 920  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQG 979

Query: 357  PLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHN 415
            P+  T  +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V   
Sbjct: 980  PVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEME 1036

Query: 416  HYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNM 475
                     F + ++     E+        + V+ F  T WP  H VP     L+  +  
Sbjct: 1037 PLAEYVVRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRR 1085

Query: 476  VERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
            V +       GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V
Sbjct: 1086 V-KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMV 1144

Query: 536  E 536
            +
Sbjct: 1145 Q 1145


>AL034349-1|CAI23054.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>AF533875-1|AAO49502.1| 1440|Homo sapiens mutant receptor type protein
            tyrosine phosphatase K protein.
          Length = 1440

 Score =  326 bits (802), Expect = 2e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQRTDYGP--VCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  + G     +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>L77886-1|AAC37599.1| 1440|Homo sapiens protein tyrosine phosphatase
            protein.
          Length = 1440

 Score =  326 bits (800), Expect = 4e-88
 Identities = 183/494 (37%), Positives = 269/494 (54%), Gaps = 27/494 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP  +TV DFWRMIWQE++A IVM+T   +  +V C +YWP   +  E YG
Sbjct: 952  RPSHYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            D  V  V+ E LA + +RTF L   E+    E R + QFH+T W  H  P+ +  LL F 
Sbjct: 1009 DFKVTCVEMEPLAEYVVRTFTL---ERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFI 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G Y+ ID  L++AE E   D++ C+K LR
Sbjct: 1066 RRVKLSNP------PSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  PV E         + D  T  +  + E+Q
Sbjct: 1120 SRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMIRIDSQTNSSHLKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+      N +KNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1180 TLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            Y +P  +I T++PL  T  +FW LVYDY C ++V+L      SQ  P +WPE     +YG
Sbjct: 1239 YRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQGCPQYWPE-EGMLRYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ +S +   ++   IFR    I +LT    G       VQ FQ   W    +VP 
Sbjct: 1297 PI-QVECMSCSMDCDVINRIFR----ICNLTRPQEGY----LMVQQFQYLGWASHREVPG 1347

Query: 465  STNSLVELMNMVERWRQ--RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  S ++L+  VE+W++  +   G   +   +G  R+G++CA    +E V +   VDVF 
Sbjct: 1348 SKRSFLKLILQVEKWQEECKEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFH 1407

Query: 523  AVKTVRRHRPQLVE 536
            AVKT+R  +P +VE
Sbjct: 1408 AVKTLRNSKPNMVE 1421



 Score =  108 bits (260), Expect = 1e-22
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 12/211 (5%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR+++     +IVML +    +   C QYWP  +E 
Sbjct: 1236 MDSYRQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVD--LSQGCPQYWP--EEG 1291

Query: 101  DETYGDISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS 157
               YG I V  +    + ++ N   R   L + ++G ++    + QF Y  W SH     
Sbjct: 1292 MLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM----VQQFQYLGWASHR-EVP 1346

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
             +   F                  G  ++HC +GGGRSG++ AI   +E+ + ++  DVF
Sbjct: 1347 GSKRSFLKLILQVEKWQEECKEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVF 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              +K LR S+  ++E  EQY+F YD   E++
Sbjct: 1407 HAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1437



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +  NR KNR   ++  D+ R  L   + +  +DYINA ++DGY +P  YIAT+ P+  T 
Sbjct: 908  KDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHETV 967

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +++  + A +V++  +      +   +WP+   ++ YG  F +  V         
Sbjct: 968  YDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD--DTEVYGD-FKVTCVEMEPLAEYV 1024

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
               F + ++     E+        + V+ F  T WP  H VP     L+  +  V +   
Sbjct: 1025 VRTFTLERR--GYNEI--------REVKQFHFTGWP-DHGVPYHATGLLSFIRRV-KLSN 1072

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G Y   +  ++   + G VD++  VK +R  R  +V+
Sbjct: 1073 PPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQ 1127


>Z93942-7|CAI19871.1| 1440|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>Z93942-6|CAI19870.1| 1431|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>Z93942-4|CAI19865.1| 1463|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>Z93942-3|CAI19868.1| 1450|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>Z93942-2|CAI19867.1| 1444|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>Z93942-1|CAI19866.1| 1441|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL136461-7|CAH72559.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL136461-6|CAH72558.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL136461-4|CAH72553.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL136461-3|CAH72556.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL136461-2|CAH72555.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL136461-1|CAH72554.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL121763-7|CAI23316.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL121763-6|CAI23315.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL121763-4|CAI23310.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL121763-3|CAI23313.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL121763-2|CAI23312.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL121763-1|CAI23311.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL049812-8|CAI19250.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL049812-7|CAI19256.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL049812-6|CAI19255.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL049812-4|CAI19253.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL049812-3|CAI19252.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL049812-2|CAI19251.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL035459-7|CAI22915.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL035459-6|CAI22914.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL035459-4|CAI22909.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL035459-3|CAI22912.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL035459-2|CAI22911.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL035459-1|CAI22910.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL031656-7|CAI19876.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL031656-6|CAI19882.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL031656-4|CAI19877.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL031656-3|CAI19880.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL031656-2|CAI19879.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL031656-1|CAI19878.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL024473-7|CAI22495.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL024473-6|CAI22494.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL024473-4|CAI22489.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL024473-3|CAI22492.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL024473-2|CAI22491.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL024473-1|CAI22490.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL022239-7|CAI20443.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL022239-6|CAI20442.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL022239-4|CAI20437.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL022239-3|CAI20440.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL022239-2|CAI20439.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL022239-1|CAI20438.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AL021395-7|CAI19987.1| 1440|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1440

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 952  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1008

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1009 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1065

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1066 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1119

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1120 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1179

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1180 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1238

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1239 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1296

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1297 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1347

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1348 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1407

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1408 IVKTLRNNKSNMVETLEQYK 1427



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1241 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1296

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1297 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1352

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1353 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1409

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1410 KTLRNNKSNMVETLEQYKFVYEVALEYL 1437



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 910  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 969

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 970  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1026

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1027 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1074

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1075 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1127


>AL021395-6|CAI19986.1| 1431|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1431

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 999

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1000 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1056

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1057 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1110

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1111 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1170

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1171 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1229

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1230 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1287

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1288 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1338

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1339 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1398

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1399 IVKTLRNNKSNMVETLEQYK 1418



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1232 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1287

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1288 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1343

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1344 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1400

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1401 KTLRNNKSNMVETLEQYKFVYEVALEYL 1428



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 961  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1017

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1018 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1065

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1066 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1118


>AL021395-4|CAI19981.1| 1463|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AL021395-3|CAI19984.1| 1450|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1450

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 962  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1018

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1019 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1075

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1076 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1129

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1130 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1189

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1190 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1248

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1249 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1306

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1307 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1357

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1358 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1417

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1418 IVKTLRNNKSNMVETLEQYK 1437



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1251 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1306

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1307 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1362

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1363 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1419

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1420 KTLRNNKSNMVETLEQYKFVYEVALEYL 1447



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 920  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 979

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 980  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1036

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1037 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1084

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1085 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1137


>AL021395-2|CAI19983.1| 1444|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1444

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 956  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1012

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1013 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1069

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1070 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1123

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1124 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1183

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1184 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1242

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1243 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1300

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1301 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1351

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1352 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1411

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1412 IVKTLRNNKSNMVETLEQYK 1431



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1245 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1300

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1301 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1356

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1357 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1413

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1414 KTLRNNKSNMVETLEQYKFVYEVALEYL 1441



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 914  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 973

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 974  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1030

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1031 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1078

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1079 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1131


>AL021395-1|CAI19982.1| 1441|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1441

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 953  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1009

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1010 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1066

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1067 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1120

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1121 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1180

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1181 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1239

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1240 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1297

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1298 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1348

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1408

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1409 IVKTLRNNKSNMVETLEQYK 1428



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1242 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1297

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1298 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1353

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1354 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1410

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1411 KTLRNNKSNMVETLEQYKFVYEVALEYL 1438



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 911  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 970

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 971  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1027

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1028 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1075

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1076 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1128


>AF043644-1|AAD09421.2| 1463|Homo sapiens receptor protein tyrosine
            phosphatase protein.
          Length = 1463

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 975  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1031

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1032 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1088

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1089 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1142

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1143 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1202

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1203 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1261

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1319

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1320 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1370

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1371 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1430

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1431 IVKTLRNNKSNMVETLEQYK 1450



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1264 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1319

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1320 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1375

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1376 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1432

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1433 KTLRNNKSNMVETLEQYKFVYEVALEYL 1460



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 933  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 992

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 993  FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1049

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1050 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1097

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1098 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1150


>AB006621-1|BAA22952.2| 1471|Homo sapiens KIAA0283 protein.
          Length = 1471

 Score =  324 bits (796), Expect = 1e-87
 Identities = 186/500 (37%), Positives = 279/500 (55%), Gaps = 27/500 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +V CV+YWP   +  E YG
Sbjct: 983  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYG 1039

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFX 164
            DI V +++ E LA + IRTF + K  KG   E R +  FH+T W  H  P ++  LL F 
Sbjct: 1040 DIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFHFTSWPDHGVPCYATGLLGFV 1096

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P AGP+VVHC+ G GR+G ++AID  L++AE E   D+F C+++LR
Sbjct: 1097 RQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELR 1150

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  L++ EEQY FV+D + E  +CG +  PV E        S+ DP T  ++ + E+Q
Sbjct: 1151 AQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQ 1210

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TPR    DC+ G    N +KNR + V+P D   P+L S  G S ++YINA  +D 
Sbjct: 1211 TLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGES-SNYINAALMDS 1269

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYG 404
            + +P  ++ T+ PL  T  +FW LV+DY C++VV+L      +Q    +WPE + S  YG
Sbjct: 1270 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEMDTAQFCMQYWPE-KTSGCYG 1327

Query: 405  PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPS 464
            P+  ++ VS +   +I   IFRI          MA  +   + VQ  Q   WP     P 
Sbjct: 1328 PI-QVEFVSADIDEDIIHRIFRICN--------MARPQDGYRIVQHLQYIGWPAYRDTPP 1378

Query: 465  STNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
            S  SL++++  +E+W+++ D   G   V   +G  R+G +CA  +  E + +   +DVF 
Sbjct: 1379 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFH 1438

Query: 523  AVKTVRRHRPQLVENMCELK 542
             VKT+R ++  +VE + + K
Sbjct: 1439 IVKTLRNNKSNMVETLEQYK 1458



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1272 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1327

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1328 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1383

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1384 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1440

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1441 KTLRNNKSNMVETLEQYKFVYEVALEYL 1468



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 63/233 (27%), Positives = 110/233 (47%), Gaps = 16/233 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 941  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 1000

Query: 365  FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTW 423
            FW +++    A++V++  +      +   +WP+   ++ YG +  +  +           
Sbjct: 1001 FWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDI-KVTLIETEPLAEYVIR 1057

Query: 424  IFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRT 483
             F + KK     E+        + ++LF  T WP  H VP     L+  +  V ++    
Sbjct: 1058 TFTVQKK--GYHEI--------RELRLFHFTSWP-DHGVPCYATGLLGFVRQV-KFLNPP 1105

Query: 484  DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  LV+
Sbjct: 1106 EAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQ 1158


>BC051651-1|AAH51651.1| 1390|Homo sapiens PTPRM protein protein.
          Length = 1390

 Score =  320 bits (785), Expect = 2e-86
 Identities = 179/502 (35%), Positives = 279/502 (55%), Gaps = 31/502 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P  YI TQGP ++T+ DFWRM+W E  A+I+M+T   +  +V C +YWP   +  E Y 
Sbjct: 902  RPNHYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYK 958

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFX 164
            DI V +++ E LA + IRTF +   EK  V E R I QFH+T W     P+ +  LL F 
Sbjct: 959  DIKVTLIETELLAEYVIRTFAV---EKRGVHEIREIRQFHFTGWPDRGVPYHATGLLGFV 1015

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                          P+AGP+VVHC+ G GR+G ++ ID  L++AE E   D++ C+++LR
Sbjct: 1016 RQVKSKSP------PSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELR 1069

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ EEQY F++D + E  +CG +  P S++       ++ DP T  ++ ++E++
Sbjct: 1070 SRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKLDPQTNSSQIKEEFR 1129

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
             +   TP   + DC+      N EKNR + ++PPD   P+L +  G S ++YINA  +D 
Sbjct: 1130 TLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGES-SNYINAALMDS 1188

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CVPPKNSQQYPPFWPE-GRHSKK 402
            Y +P  +I T+ PL  T  +FW LV DY C +VV+L  V P  +Q  P +WPE G H  +
Sbjct: 1189 YKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGVH--R 1244

Query: 403  YGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKV 462
            +GP+  ++ VS +   +I + IFRI           A  +   + VQ FQ   WPM    
Sbjct: 1245 HGPI-QVEFVSADLEEDIISRIFRIYN--------AARPQDGYRMVQQFQFLGWPMYRDT 1295

Query: 463  PSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDV 520
            P S  S ++L+  V++W++  +   G   V   +G  R+G +CA +   E +     VDV
Sbjct: 1296 PVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDV 1355

Query: 521  FQAVKTVRRHRPQLVENMCELK 542
            F AVKT+R ++P +V+ + + K
Sbjct: 1356 FHAVKTLRNNKPNMVDLLDQYK 1377



 Score =  106 bits (254), Expect = 5e-22
 Identities = 66/212 (31%), Positives = 98/212 (46%), Gaps = 8/212 (3%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  +P A+IVTQ P  +TV DFWR++      ++VML         +C QYWP N   
Sbjct: 1186 MDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGV- 1242

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHT-CPFSNA 159
               +G I V  V  +   +   R FR+Y   +      R + QF +  W  +   P S  
Sbjct: 1243 -HRHGPIQVEFVSADLEEDIISRIFRIYNAARPQD-GYRMVQQFQFLGWPMYRDTPVSKR 1300

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
               F              N   G  VVHC +GGGRSG + AI    E+   + + DVF  
Sbjct: 1301 --SFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHA 1358

Query: 220  LKKLRESRKGLIENEEQYKFVYDTLEEHVVCG 251
            +K LR ++  +++  +QYKF Y+   E++  G
Sbjct: 1359 VKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG 1390



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 61/235 (25%), Positives = 111/235 (47%), Gaps = 16/235 (6%)

Query: 303  RGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQ 362
            +G+NR KNR   ++  D+ R  L + +G++ +DYIN  ++DGY +P  YIAT+ P+  T 
Sbjct: 858  KGENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQGPMQETI 917

Query: 363  GEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIK 421
             +FW +V+    A+++++  +      +   +WP+     K   V  I+      Y  I+
Sbjct: 918  YDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYV-IR 976

Query: 422  TWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQ 481
            T  F + K+         GV    + ++ F  T WP    VP     L+  +  V+  + 
Sbjct: 977  T--FAVEKR---------GVH-EIREIRQFHFTGWP-DRGVPYHATGLLGFVRQVKS-KS 1022

Query: 482  RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
                GP+ V    G  R G +   +  ++   + G VD++  V+ +R  R  +V+
Sbjct: 1023 PPSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQ 1077


>U73727-1|AAB51343.1| 1436|Homo sapiens receptor protein tyrosine
            phosphatase hPTP-J precursor protein.
          Length = 1436

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 948  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1004

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1005 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1061

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1062 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1115

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1116 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1175

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1176 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1234

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1235 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1291

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1292 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1343

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1344 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1403

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1404 TLRNYKPNMVETM 1416



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1230 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1289

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1290 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1343

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1344 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1398

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1399 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1430



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 916  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 975

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 976  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1025

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1026 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1080

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1081 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1119


>AL645859-2|CAH72393.1| 1436|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1436

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 948  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1004

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1005 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1061

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1062 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1115

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1116 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1175

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1176 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1234

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1235 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1291

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1292 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1343

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1344 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1403

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1404 TLRNYKPNMVETM 1416



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1230 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1289

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1290 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1343

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1344 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1398

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1399 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1430



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 916  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 975

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 976  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1025

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1026 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1080

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1081 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1119


>AL645859-1|CAH72394.1| 1446|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1446

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 958  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1014

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1015 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1071

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1072 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1125

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1126 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1185

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1186 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1244

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1245 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1301

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1302 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1353

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1354 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1413

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1414 TLRNYKPNMVETM 1426



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1240 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1299

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1300 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1353

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1354 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1408

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1409 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1440



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 926  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 985

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 986  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1035

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1036 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1090

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1091 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1129


>AL590729-6|CAI14332.1| 1446|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1446

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 958  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1014

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1015 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1071

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1072 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1125

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1126 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1185

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1186 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1244

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1245 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1301

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1302 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1353

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1354 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1413

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1414 TLRNYKPNMVETM 1426



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1240 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1299

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1300 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1353

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1354 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1408

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1409 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1440



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 926  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 985

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 986  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1035

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1036 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1090

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1091 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1129


>AL590729-5|CAI14331.1| 1436|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1436

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 948  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1004

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1005 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1061

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1062 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1115

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1116 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1175

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1176 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1234

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1235 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1291

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1292 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1343

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1344 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1403

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1404 TLRNYKPNMVETM 1416



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1230 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1289

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1290 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1343

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1344 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1398

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1399 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1430



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 916  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 975

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 976  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1025

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1026 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1080

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1081 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1119


>AL049570-2|CAI20947.1| 1446|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1446

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 958  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1014

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1015 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1071

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1072 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1125

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1126 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1185

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1186 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1244

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1245 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1301

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1302 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1353

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1354 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1413

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1414 TLRNYKPNMVETM 1426



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1240 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1299

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1300 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1353

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1354 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1408

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1409 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1440



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 926  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 985

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 986  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1035

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1036 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1090

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1091 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1129


>AL049570-1|CAI20946.1| 1436|Homo sapiens protein tyrosine
            phosphatase, receptor type, U protein.
          Length = 1436

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 948  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1004

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1005 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1061

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1062 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1115

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1116 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1175

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1176 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1234

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1235 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1291

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1292 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1343

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1344 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1403

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1404 TLRNYKPNMVETM 1416



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1230 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1289

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1290 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1343

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1344 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1398

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1399 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1430



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 916  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 975

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 976  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1025

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1026 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1080

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1081 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1119


>AB208855-1|BAD92092.1| 1243|Homo sapiens Receptor protein tyrosine
            phosphatase hPTP-J precursor variant protein.
          Length = 1243

 Score =  316 bits (777), Expect = 2e-85
 Identities = 173/493 (35%), Positives = 269/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 755  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 811

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 812  MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 868

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 869  ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 922

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 923  NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 982

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 983  VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1041

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1042 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1098

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1099 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1150

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1151 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1210

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1211 TLRNYKPNMVETM 1223



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 60/212 (28%), Positives = 95/212 (44%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1037 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1096

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1097 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1150

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1151 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1205

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD   E++
Sbjct: 1206 FFAAKTLRNYKPNMVETMDQYHFCYDVALEYL 1237



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319 DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
           D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 723 DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 782

Query: 379 VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
           ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 783 MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 832

Query: 438 MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
             G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 833 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 887

Query: 498 RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 888 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 926


>U71075-1|AAC51938.1| 1439|Homo sapiens protein tyrosine phosphatase
            receptor omicron protein.
          Length = 1439

 Score =  314 bits (771), Expect = 1e-84
 Identities = 174/493 (35%), Positives = 269/493 (54%), Gaps = 30/493 (6%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 953  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1009

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1010 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1066

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1067 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1120

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1121 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1180

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1181 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1239

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
            R +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1240 RAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1296

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+ + I     L+         V+ FQ   W      P S
Sbjct: 1297 LMEVEFMSGTADEDLVARVFRV-QNISREGHLL---------VRHFQFLRWSAYRDTPDS 1346

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1347 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEIIRCHNLVDVFFAAK 1406

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1407 TLRNYKPNMVETM 1419



 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 58/210 (27%), Positives = 93/210 (44%), Gaps = 15/210 (7%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  + +A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1235 SYTRSRAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1294

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSN 158
               YG + V  +      +   R FR+    +   +    +  F + +W ++  T     
Sbjct: 1295 ---YGLMEVEFMSGTADEDLVARVFRVQNISREGHL---LVRHFQFLRWSAYRDTPDSKK 1348

Query: 159  ALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFG 218
            A L                    G  +VHC +GGGRSG + A    LE+    +  DVF 
Sbjct: 1349 AFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEIIRCHNLVDVFF 1403

Query: 219  CLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              K LR  +  ++E  +QY F YD   E++
Sbjct: 1404 AAKTLRNYKPNMVETMDQYHFCYDVALEYL 1433



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 56/225 (24%), Positives = 92/225 (40%), Gaps = 22/225 (9%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVD------GYTKPREYIATEWPLMMTQGEFWSLVYDY 372
            D  R  L    G+   DYINA ++D      GY +   +IAT+ P      +FW +V+  
Sbjct: 915  DRHRVKLHPMLGDPNADYINANYIDIRINREGYHRSNHFIATQGPKPEMVYDFWRMVWQE 974

Query: 373  ECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKI 431
             C+++V++  +      +   +WPE   S  YG +  I  V            F + ++ 
Sbjct: 975  HCSSIVMITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR- 1030

Query: 432  ISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVV 491
                    G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ + 
Sbjct: 1031 --------GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIH 1079

Query: 492  SPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
               G  R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1080 CSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1124


>U60289-1|AAB07074.1| 1436|Homo sapiens receptor protein tyrosine
            phosphatase psi protein.
          Length = 1436

 Score =  313 bits (769), Expect = 2e-84
 Identities = 172/493 (34%), Positives = 268/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 948  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 1004

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1005 MLVKTETLAEYVVRTFALERRGYSARHEVR---QFHFTAWPEHGVPYHATGLLAFIRRVK 1061

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1062 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1115

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1116 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1175

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+P D   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1176 VTPPLDVEECSIALLPRNRDKNRSMDVLPADRCLPFLISTDGDS-NNYINAALTDSYTRS 1234

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1235 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1291

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1292 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1343

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A K
Sbjct: 1344 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAK 1403

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1404 TLRNYKPNMVETM 1416



 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 60/212 (28%), Positives = 96/212 (45%), Gaps = 17/212 (8%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1230 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1289

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSH--TCPF 156
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++  T   
Sbjct: 1290 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1343

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
              A L                    G  +VHC +GGGRSG + A    LE+    +  DV
Sbjct: 1344 KKAFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDV 1398

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
            F   K LR  +  ++E  +QY F YD + E++
Sbjct: 1399 FFAAKTLRNYKPNMVETMDQYHFCYDVVLEYL 1430



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/219 (25%), Positives = 92/219 (42%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 916  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 975

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 976  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1025

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+ F  T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1026 --GYSA-RHEVRQFHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1080

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1081 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1119


>X97198-1|CAA65832.1| 1430|Homo sapiens receptor phosphatase PCP-2
            protein.
          Length = 1430

 Score =  310 bits (762), Expect = 1e-83
 Identities = 170/493 (34%), Positives = 268/493 (54%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +  +V C +YWP   E  +TYGDI +
Sbjct: 942  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSRYWP---EDSDTYGDIKI 998

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   Q H+T W  H  P+ +  LL F     
Sbjct: 999  MLVKTETLAEYVVRTFALERRGYSARHEVR---QSHFTAWPEHGVPYHATGLLAFIRRVK 1055

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L   R 
Sbjct: 1056 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRV 1109

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1110 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1169

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + +C+      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1170 VTPPLDVEECSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRR 1228

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              ++ T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1229 SAFMVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1285

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1286 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----DLLVRHFQFLRWSAYRDTPDS 1337

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R+G +CA    +E +  H  VDVF A +
Sbjct: 1338 KKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFFAAQ 1397

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1398 TLRNYKPNMVETM 1410



 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 56/210 (26%), Positives = 93/210 (44%), Gaps = 13/210 (6%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A++VT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1224 SYTRRSAFMVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1283

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSN 158
               YG + V  +      +   R FR+    + +   +  +  F + +W ++  T     
Sbjct: 1284 ---YGLMEVEFMSGTADEDLVARVFRVQNISR-LQEGDLLVRHFQFLRWSAYRDTPDSKK 1339

Query: 159  ALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFG 218
            A L                    G  +VHC +GGGRSG + A    LE+    +  DVF 
Sbjct: 1340 AFLHLLAEVDKWQAESGD-----GRTIVHCLNGGGRSGTFCACATVLEMIRCHNLVDVFF 1394

Query: 219  CLKKLRESRKGLIENEEQYKFVYDTLEEHV 248
              + LR  +  ++E  +QY F YD   E++
Sbjct: 1395 AAQTLRNYKPNMVETMDQYHFCYDVALEYL 1424



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 16/219 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 910  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 969

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 970  MITKLVEVGRVKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1019

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A    V+    T WP  H VP     L+  +  V+      D GP+ +    G  
Sbjct: 1020 --GYSA-RHEVRQSHFTAWP-EHGVPYHATGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1074

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            R G Y   +  ++     G VD++  VKT+   R  +++
Sbjct: 1075 RTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQ 1113


>Z93942-5|CAI19869.1| 1451|Homo sapiens protein tyrosine phosphatase,
            receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL136461-5|CAH72557.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL121763-5|CAI23314.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL049812-5|CAI19254.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL035459-5|CAI22913.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL031656-5|CAI19881.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL024473-5|CAI22493.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL022239-5|CAI20441.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>AL021395-5|CAI19985.1| 1451|Homo sapiens protein tyrosine
            phosphatase, receptor type, T protein.
          Length = 1451

 Score =  304 bits (747), Expect = 1e-81
 Identities = 186/520 (35%), Positives = 279/520 (53%), Gaps = 47/520 (9%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIK------------------ 87
            +P+ YI TQGP ++TV DFWRMIWQE +A+IVM+T   +  +                  
Sbjct: 943  RPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASP 1002

Query: 88   --VMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFH 145
              V CV+YWP   +  E YGDI V +++ E LA + IRTF + K  KG   E R +  FH
Sbjct: 1003 GMVKCVRYWP---DDTEVYGDIKVTLIETEPLAEYVIRTFTVQK--KGYH-EIRELRLFH 1056

Query: 146  YTQWHSHTCP-FSNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN 204
            +T W  H  P ++  LL F               P AGP+VVHC+ G GR+G ++AID  
Sbjct: 1057 FTSWPDHGVPCYATGLLGFVRQVKFLNP------PEAGPIVVHCSAGAGRTGCFIAIDTM 1110

Query: 205  LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
            L++AE E   D+F C+++LR  R  L++ EEQY FV+D + E  +CG +  PV E     
Sbjct: 1111 LDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLY 1170

Query: 265  KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
               S+ DP T  ++ + E+Q +   TPR    DC+ G    N +KNR + V+P D   P+
Sbjct: 1171 YNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPF 1230

Query: 325  LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP 384
            L S  G S ++YINA  +D + +P  ++ T+ PL  T  +FW LV+DY C++VV+L    
Sbjct: 1231 LISVDGES-SNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVML-NEM 1288

Query: 385  KNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              +Q    +WPE + S  YGP+  ++ VS +   +I   IFRI          MA  +  
Sbjct: 1289 DTAQFCMQYWPE-KTSGCYGPI-QVEFVSADIDEDIIHRIFRICN--------MARPQDG 1338

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVY 502
             + VQ  Q   WP     P S  SL++++  +E+W+++ D   G   V   +G  R+G +
Sbjct: 1339 YRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTF 1398

Query: 503  CAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
            CA  +  E + +   +DVF  VKT+R ++  +VE + + K
Sbjct: 1399 CAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYK 1438



 Score =  108 bits (260), Expect = 1e-22
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 16/208 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P A++VTQ P  +TV DFWR+++    +++VML +  D  +  C+QYWP  ++    YG
Sbjct: 1252 QPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNE-MDTAQ-FCMQYWP--EKTSGCYG 1307

Query: 106  DISVGIVQ---EEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSH--TCPFSNAL 160
             I V  V    +E++ +   R   + + + G     R +    Y  W ++  T P   +L
Sbjct: 1308 PIQVEFVSADIDEDIIHRIFRICNMARPQDGY----RIVQHLQYIGWPAYRDTPPSKRSL 1363

Query: 161  LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCL 220
            L+                   G  VVHC +GGGRSG + AI +  E+ ++++  DVF  +
Sbjct: 1364 LKVVRRLEKWQEQYDGRE---GRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIV 1420

Query: 221  KKLRESRKGLIENEEQYKFVYDTLEEHV 248
            K LR ++  ++E  EQYKFVY+   E++
Sbjct: 1421 KTLRNNKSNMVETLEQYKFVYEVALEYL 1448



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 16/243 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++  D+ R  L    G+  +DYINA ++DGY +PR YIAT+ P+  T  +
Sbjct: 901  ENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKD 960

Query: 365  FWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            FW +++  E +A +V+        ++P     G  +   G   +   V    Y    T +
Sbjct: 961  FWRMIWQ-ENSASIVMVTNLVEVGRHPAEHTVG--NATLGRAASPGMVKCVRYWPDDTEV 1017

Query: 425  FRINKKIISLTELMAGVKAPTKTVQ-----------LFQLTCWPMGHKVPSSTNSLVELM 473
            +   K  +  TE +A     T TVQ           LF  T WP  H VP     L+  +
Sbjct: 1018 YGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWP-DHGVPCYATGLLGFV 1076

Query: 474  NMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQ 533
              V ++    + GP+ V    G  R G + A +  ++     G VD+F  V+ +R  R  
Sbjct: 1077 RQV-KFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVN 1135

Query: 534  LVE 536
            LV+
Sbjct: 1136 LVQ 1138


>X95712-1|CAA65016.1| 1442|Homo sapiens FMI protein protein.
          Length = 1442

 Score =  301 bits (740), Expect = 7e-81
 Identities = 169/493 (34%), Positives = 262/493 (53%), Gaps = 28/493 (5%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I TQGP  + V DFWRM+WQE  ++IVM+TK  +     C +YWP   E  +TYGDI +
Sbjct: 955  FIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVAGCKCSRYWP---EDSDTYGDIKI 1011

Query: 110  GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPF-SNALLEFXXXXX 168
             +V+ E LA + +RTF L +       E R   QFH+T W  H  P+ +  LL F     
Sbjct: 1012 MLVKTETLAEYVVRTFALERRGYSARYEVR---QFHFTAWPEHGVPYHTTGLLAFIRRVK 1068

Query: 169  XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                      P AGP+V+HC+ G GR+G Y+ +D  L++AE E   D++ C+K L     
Sbjct: 1069 ASTP------PDAGPIVIHCSAGTGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRCV 1122

Query: 229  GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
             +I+ EEQY F++D + E  +CG +  PVSE     K+  + DP +  ++ ++E+Q +  
Sbjct: 1123 NMIQTEEQYIFIHDAILEACLCGETTIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNS 1182

Query: 289  QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKP 348
             TP   + + +      NR+KNR + V+PPD   P+L S  G+S  +YINA   D YT+ 
Sbjct: 1183 VTPPLDVEEYSIALLPRNRDKNRSMDVLPPDRCLPFLISTDGDS-NNYINAALTDSYTRS 1241

Query: 349  REYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYP--PFWPE-GRHSKKYGP 405
              +I T  PL  T  +FW LVYDY C ++V+L    +++  +P   +WPE GR  ++YG 
Sbjct: 1242 AAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGR--QQYG- 1298

Query: 406  VFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSS 465
            +  ++ +S     ++   +FR+     +++ L  G       V+ FQ   W      P S
Sbjct: 1299 LMEVEFMSGTADEDLVARVFRVQ----NISRLQEG----HLLVRHFQFLRWSAYRDTPDS 1350

Query: 466  TNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVK 525
              + + L+  V++W+  +  G   V   +G  R G  CA    +E +  H  VDV  A K
Sbjct: 1351 EKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRRGTSCALRTVLEMIRCHNLVDVSFAAK 1410

Query: 526  TVRRHRPQLVENM 538
            T+R ++P +VE M
Sbjct: 1411 TLRNYKPNMVETM 1423



 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 15/215 (6%)

Query: 43   SLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVM-CVQYWP-PNKEK 100
            S  +  A+IVT  P + T  DFWR+++     +IVML +         C+QYWP P +++
Sbjct: 1237 SYTRSAAFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ 1296

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFIL--QFHYTQWHSHT-CPFS 157
               YG + V  +      +   R FR+    +   ++E  +L   F + +W ++   P S
Sbjct: 1297 ---YGLMEVEFMSGTADEDLVARVFRVQNISR---LQEGHLLVRHFQFLRWSAYRDTPDS 1350

Query: 158  NALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVF 217
                E                   G  +VHC +GGGR G   A+   LE+    +  DV 
Sbjct: 1351 ----EKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRRGTSCALRTVLEMIRCHNLVDVS 1406

Query: 218  GCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGI 252
               K LR  +  ++E  +QY F YD   E++  G+
Sbjct: 1407 FAAKTLRNYKPNMVETMDQYHFCYDVALEYLEAGV 1441



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 16/210 (7%)

Query: 319  DNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVV 378
            D  R  L    G+   DYINA ++DGY +   +IAT+ P      +FW +V+   C+++V
Sbjct: 923  DRHRVKLHPMLGDPNADYINANYIDGYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIV 982

Query: 379  VLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTEL 437
            ++  +      +   +WPE   S  YG +  I  V            F + ++       
Sbjct: 983  MITKLVEVAGCKCSRYWPE--DSDTYGDI-KIMLVKTETLAEYVVRTFALERR------- 1032

Query: 438  MAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRS 497
              G  A  + V+ F  T WP  H VP  T  L+  +  V+      D GP+ +    G  
Sbjct: 1033 --GYSARYE-VRQFHFTAWP-EHGVPYHTTGLLAFIRRVKA-STPPDAGPIVIHCSAGTG 1087

Query: 498  RAGVYCAANACIEQVIKHGEVDVFQAVKTV 527
            R G Y   +  ++     G VD++  VKT+
Sbjct: 1088 RTGCYIVLDVMLDMAECEGVVDIYNCVKTL 1117


>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
            phosphatase, receptor type, sigma isoform 3 precursor
            variant protein.
          Length = 1560

 Score =  264 bits (647), Expect = 1e-69
 Identities = 164/501 (32%), Positives = 262/501 (52%), Gaps = 35/501 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +  AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG
Sbjct: 1052 RQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYG 1109

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+  
Sbjct: 1110 FIQVTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPT 1160

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R
Sbjct: 1161 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1220

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++
Sbjct: 1221 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1280

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1281 RLANSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1335

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S
Sbjct: 1336 IDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-S 1394

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1395 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1442

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1443 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1502

Query: 520  VFQAVKTVRRHRPQLVENMCE 540
            +FQ VK +R  RP +V+   E
Sbjct: 1503 IFQTVKMLRTQRPAMVQTETE 1523



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L   +G   +DYINA +VDGY +   YIAT+ PL  T G+F
Sbjct: 1011 NKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDF 1070

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 1071 WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1125

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1126 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1176

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1177 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1228


>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
            sigma protein.
          Length = 1948

 Score =  263 bits (645), Expect = 2e-69
 Identities = 163/497 (32%), Positives = 261/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +  AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG
Sbjct: 1457 RQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYG 1514

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+  
Sbjct: 1515 FIQVTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPT 1565

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R
Sbjct: 1566 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1625

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++
Sbjct: 1626 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1685

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1686 RLANSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1740

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S
Sbjct: 1741 IDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-S 1799

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1800 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1847

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1848 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1907

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1908 IFQTVKMLRTQRPAMVQ 1924



 Score =  121 bits (291), Expect = 2e-26
 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1748 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1805

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1806 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1862

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1863 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1918

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E++Y+F Y    E++
Sbjct: 1919 RPAMVQTEDEYQFCYQAALEYL 1940



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 70/232 (30%), Positives = 112/232 (48%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+FR  L   +G   +DYINA +VDGY +   YIAT+ PL  T G+F
Sbjct: 1416 NKPKNRYANVIAYDHFRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDF 1475

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 1476 WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1530

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1531 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1581

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1582 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1633


>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
            phosphatase, receptor type, S protein.
          Length = 1501

 Score =  263 bits (645), Expect = 2e-69
 Identities = 163/497 (32%), Positives = 261/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +  AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG
Sbjct: 1010 RQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYG 1067

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+  
Sbjct: 1068 FIQVTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPT 1118

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R
Sbjct: 1119 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1178

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++
Sbjct: 1179 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1238

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1239 RLANSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1293

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S
Sbjct: 1294 IDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-S 1352

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1353 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1400

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1401 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1460

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1461 IFQTVKMLRTQRPAMVQ 1477



 Score =  121 bits (291), Expect = 2e-26
 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1301 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1358

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1359 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1415

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1416 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1471

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E++Y+F Y    E++
Sbjct: 1472 RPAMVQTEDEYQFCYQAALEYL 1493



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L   +G   +DYINA +VDGY +   YIAT+ PL  T G+F
Sbjct: 969  NKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDF 1028

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 1029 WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1083

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1084 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1134

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1135 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1186


>AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]
            protein.
          Length = 1399

 Score =  263 bits (644), Expect = 3e-69
 Identities = 163/494 (32%), Positives = 260/494 (52%), Gaps = 35/494 (7%)

Query: 49   AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
            AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG I 
Sbjct: 933  AYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYGFIQ 990

Query: 109  VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
            V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+     
Sbjct: 991  VTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPTPFL 1041

Query: 169  XXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                     NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R  R
Sbjct: 1042 AFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQR 1101

Query: 228  KGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQIC 287
              +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++++ 
Sbjct: 1102 NYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLA 1161

Query: 288  K---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDG 344
                 T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F+DG
Sbjct: 1162 NSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDG 1216

Query: 345  YTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKY 403
            Y + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S +Y
Sbjct: 1217 YRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-SARY 1275

Query: 404  GPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVP 463
               F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP    VP
Sbjct: 1276 -QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQGVP 1323

Query: 464  SSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQ 522
             S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD+FQ
Sbjct: 1324 KSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQ 1383

Query: 523  AVKTVRRHRPQLVE 536
             VK +R  RP +V+
Sbjct: 1384 TVKMLRTQRPAMVQ 1397



 Score =  109 bits (263), Expect = 4e-23
 Identities = 60/188 (31%), Positives = 90/188 (47%), Gaps = 10/188 (5%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1221 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP--AERSARYQYF 1278

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1279 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1335

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1336 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1391

Query: 227  RKGLIENE 234
            R  +++ E
Sbjct: 1392 RPAMVQTE 1399



 Score = 92.3 bits (219), Expect = 9e-18
 Identities = 69/232 (29%), Positives = 110/232 (47%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L   +G   +DYINA +VDGY     YIAT+ PL  T G+F
Sbjct: 889  NKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDF 948

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 949  WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1003

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1004 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1054

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1055 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1106


>X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphatase
            protein.
          Length = 1523

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1032 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1089

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1090 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1140

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1141 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1200

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1201 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1260

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1261 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1315

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1316 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1374

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1375 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1422

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1423 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1482

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1483 IFQTVKMLRTQRPAMVQ 1499



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1323 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1380

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1381 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1437

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1438 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1493

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1494 RPAMVQTEDQYQFSYRAALEYL 1515



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 991  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1050

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1051 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1105

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1106 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1156

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1157 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1208


>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
            delta protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
          Length = 1496

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1005 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1062

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1063 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1113

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1114 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1173

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1174 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1233

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1234 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1288

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1289 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1347

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1348 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1395

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1396 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1455

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1456 IFQTVKMLRTQRPAMVQ 1472



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1296 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1353

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1354 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1410

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1411 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1466

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1467 RPAMVQTEDQYQFSYRAALEYL 1488



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 964  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1023

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1024 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1078

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1079 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1129

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1130 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1181


>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
          Length = 1505

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1014 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1071

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1072 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1122

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1123 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1182

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1183 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1242

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1243 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1297

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1298 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1356

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1357 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1404

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1405 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1464

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1465 IFQTVKMLRTQRPAMVQ 1481



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1305 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1362

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1363 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1419

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1420 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1475

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1476 RPAMVQTEDQYQFSYRAALEYL 1497



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 973  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1032

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1033 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1087

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1088 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1138

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1139 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1190


>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
          Length = 1506

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1015 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1072

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1073 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1123

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1124 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1183

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1184 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1243

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1244 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1298

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1299 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1357

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1358 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1405

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1406 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1465

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1466 IFQTVKMLRTQRPAMVQ 1482



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1306 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1363

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1364 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1420

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1421 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1476

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1477 RPAMVQTEDQYQFSYRAALEYL 1498



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 974  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1033

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1034 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1088

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1089 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1139

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1140 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1191


>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
          Length = 1505

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1014 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1071

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1072 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1122

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1123 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1182

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1183 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1242

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1243 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1297

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1298 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1356

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1357 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1404

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1405 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1464

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1465 IFQTVKMLRTQRPAMVQ 1481



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1305 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1362

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1363 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1419

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1420 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1475

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1476 RPAMVQTEDQYQFSYRAALEYL 1497



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 973  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1032

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1033 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1087

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1088 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1138

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1139 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1190


>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
            phosphatase, receptor type, D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
            phosphatase, receptor type, D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
            phosphatase, receptor type, D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
            phosphatase, receptor type, D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
            phosphatase, receptor type, D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosphatase
            receptor type D protein.
          Length = 1912

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 1421 KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1478

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1479 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1529

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1530 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1589

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1590 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1649

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1650 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1704

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1705 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1763

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1764 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1811

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1812 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1871

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1872 IFQTVKMLRTQRPAMVQ 1888



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1769

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1770 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1826

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1827 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1882

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1883 RPAMVQTEDQYQFSYRAALEYL 1904



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 1380 NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1439

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1440 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1494

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1495 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1545

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1546 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1597


>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
            phosphatase, receptor type, D isoform 4 precursor variant
            protein.
          Length = 1478

 Score =  261 bits (640), Expect = 9e-69
 Identities = 163/497 (32%), Positives = 259/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQG   +T  DFWRMIW++R+A +VM+TK  +  +V C QYWP      ET+G
Sbjct: 987  KQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWP--SRGTETHG 1044

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             + V ++   ELA + +RTF LYK       E+R + QF +T W  H  P      E   
Sbjct: 1045 LVQVTLLDTVELATYCVRTFALYKNGSS---EKREVRQFQFTAWPDHGVP------EHPT 1095

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1096 PFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMR 1155

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F++D L E V CG +  P   L   +++ +Q +    +   + E++
Sbjct: 1156 AQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFK 1215

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +   N+ KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1216 RLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1270

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW +++++    VV+L  +     ++   +WP  R S
Sbjct: 1271 IDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAER-S 1329

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1330 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1377

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1378 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1437

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1438 IFQTVKMLRTQRPAMVQ 1454



 Score =  121 bits (291), Expect = 2e-26
 Identities = 65/202 (32%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1278 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1335

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1336 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1392

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1393 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1448

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+F Y    E++
Sbjct: 1449 RPAMVQTEDQYQFSYRAALEYL 1470



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L++ +G   +DY+NA ++DGY K   YIAT+  L  T G+F
Sbjct: 946  NKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDF 1005

Query: 366  WSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W ++++   A VV++    + S+ +   +WP  R ++ +G V     V+      + T+ 
Sbjct: 1006 WRMIWEQRSATVVMMTKLEERSRVKCDQYWP-SRGTETHGLV----QVTLLDTVELATYC 1060

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R          L     +  + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1061 VR-------TFALYKNGSSEKREVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNP-PD 1111

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1112 AGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQ 1163


>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
          Length = 1502

 Score =  261 bits (639), Expect = 1e-68
 Identities = 162/497 (32%), Positives = 260/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +  AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG
Sbjct: 1011 RQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYG 1068

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+  
Sbjct: 1069 FIQVTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPT 1119

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R
Sbjct: 1120 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1179

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++
Sbjct: 1180 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1239

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +    + KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1240 RLANSKAHTSRF-----ISANLPCKKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1294

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S
Sbjct: 1295 IDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-S 1353

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1354 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1401

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1402 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1461

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1462 IFQTVKMLRTQRPAMVQ 1478



 Score =  121 bits (291), Expect = 2e-26
 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1302 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1359

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1360 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1416

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1417 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1472

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E++Y+F Y    E++
Sbjct: 1473 RPAMVQTEDEYQFCYQAALEYL 1494



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L   +G   +DYINA +VDGY +   YIAT+ PL  T G+F
Sbjct: 970  NKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDF 1029

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 1030 WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1084

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1085 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1135

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1136 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1187


>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
          Length = 1911

 Score =  261 bits (639), Expect = 1e-68
 Identities = 162/497 (32%), Positives = 260/497 (52%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +  AYI TQGP  +T  DFWRM+W++R+A IVM+T+  +  ++ C QYWP      ETYG
Sbjct: 1420 RQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWP--NRGTETYG 1477

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA F +RTF L+K       E+R + QF +T W  H  P      E+  
Sbjct: 1478 FIQVTLLDTIELATFCVRTFSLHKNGSS---EKREVRQFQFTAWPDHGVP------EYPT 1528

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGP+VVHC+ G GR+G ++ IDA LE  + E + DV+G +  +R
Sbjct: 1529 PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMR 1588

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E V CG +  P   L   +++ +Q +P   +   + E++
Sbjct: 1589 SQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFK 1648

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
            ++      T RF        +    + KNR V ++P ++ R  L   +G   +DYINA F
Sbjct: 1649 RLANSKAHTSRF-----ISANLPCKKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASF 1703

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  T  +FW ++++     VV+L  +     ++   +WP  R S
Sbjct: 1704 IDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAER-S 1762

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++TV+ FQ T WP   
Sbjct: 1763 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTVRQFQFTDWP-EQ 1810

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP S    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1811 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1870

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VK +R  RP +V+
Sbjct: 1871 IFQTVKMLRTQRPAMVQ 1887



 Score =  121 bits (291), Expect = 2e-26
 Identities = 64/202 (31%), Positives = 99/202 (49%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  +T  DFWRM+W+  +  +VMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1711 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA--ERSARYQYF 1768

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R + QF +T W     P S    ++F   
Sbjct: 1769 VVDPMAEYNMPQYILREFKVTDARDG---QSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQ 1825

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1826 VHKTKEQFGQD----GPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQ 1881

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E++Y+F Y    E++
Sbjct: 1882 RPAMVQTEDEYQFCYQAALEYL 1903



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 15/232 (6%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            N+ KNR   V+  D+ R  L   +G   +DYINA +VDGY +   YIAT+ PL  T G+F
Sbjct: 1379 NKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDF 1438

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V++   A +V++  +  K+  +   +WP  R ++ YG +     V+      + T+ 
Sbjct: 1439 WRMVWEQRSATIVMMTRLEEKSRIKCDQYWP-NRGTETYGFI----QVTLLDTIELATFC 1493

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD 484
             R      SL +  +  K   + V+ FQ T WP  H VP      +  +  V+      D
Sbjct: 1494 VR----TFSLHKNGSSEK---REVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTCNP-PD 1544

Query: 485  YGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             GP+ V    G  R G +   +A +E++     VDV+  V  +R  R  +V+
Sbjct: 1545 AGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQ 1596


>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16 to
            1881) protein.
          Length = 1897

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1406 KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1463

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1464 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1514

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1515 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1574

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1575 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1634

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1635 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1689

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1690 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1748

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1749 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1796

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1797 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1856

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1857 MFQTVKTLRTQRPAMVQ 1873



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1697 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1754

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1755 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1811

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1812 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1867

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1868 RPAMVQTEDQYQLCYRAALEYL 1889



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 1323 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 1374

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 1375 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1434

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1435 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1487

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1488 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1539

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1540 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1582


>BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein
            protein.
          Length = 1191

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 700  KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 757

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 758  LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 808

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 809  PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 868

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 869  SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 928

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 929  LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 983

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 984  LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1042

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1043 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1090

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1091 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1150

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1151 MFQTVKTLRTQRPAIVQ 1167



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 991  KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1048

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1049 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1105

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1106 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1161

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1162 RPAIVQTEDQYQLCYRAALEYL 1183



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256 PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
           P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 617 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 668

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 669 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 728

Query: 376 AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 729 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 781

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 782 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 833

Query: 494 DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 834 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 876


>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
            phosphatase, receptor type, F protein.
          Length = 1907

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1416 KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1473

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1474 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1524

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1525 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1584

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1585 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1644

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1645 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1699

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1700 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1758

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1759 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1806

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1807 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1866

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1867 MFQTVKTLRTQRPAMVQ 1883



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1707 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1764

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1765 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1821

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1822 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1877

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1878 RPAMVQTEDQYQLCYRAALEYL 1899



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 1333 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 1384

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 1385 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1444

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1445 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1497

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1498 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1549

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1550 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1592


>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
            phosphatase, receptor type, F protein.
          Length = 1898

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1407 KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1464

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1465 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1515

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1516 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1575

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1576 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1635

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1636 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1690

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1691 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1749

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1750 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1797

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1798 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1857

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1858 MFQTVKTLRTQRPAMVQ 1874



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1698 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1755

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1756 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1812

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1813 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1868

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1869 RPAMVQTEDQYQLCYRAALEYL 1890



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 1324 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 1375

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 1376 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1435

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1436 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1488

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1489 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1540

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1541 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1583


>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
          Length = 1918

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1427 KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1484

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1485 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1535

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1536 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1595

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1596 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1655

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1656 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1710

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1711 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1769

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1770 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1817

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1818 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1877

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1878 MFQTVKTLRTQRPAMVQ 1894



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1718 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1775

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1776 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1832

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1833 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1888

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1889 RPAMVQTEDQYQLCYRAALEYL 1910



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 1344 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 1395

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 1396 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1455

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1456 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1508

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1509 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1560

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1561 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1603


>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
            protein.
          Length = 1484

 Score =  253 bits (620), Expect = 2e-66
 Identities = 157/497 (31%), Positives = 257/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 993  KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1050

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1051 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1101

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1102 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1161

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1162 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1221

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1222 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1276

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1277 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1335

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1336 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1383

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1384 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1443

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1444 MFQTVKTLRTQRPAMVQ 1460



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1284 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1341

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1342 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1398

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1399 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1454

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1455 RPAMVQTEDQYQLCYRAALEYL 1476



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 910  PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 961

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 962  IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1021

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1022 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1074

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1075 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1126

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1127 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1169


>AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine
            phosphatase, receptor type, F isoform 2 precursor variant
            protein.
          Length = 1552

 Score =  252 bits (616), Expect = 7e-66
 Identities = 157/497 (31%), Positives = 256/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AYI TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1061 KQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1118

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1119 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1169

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1170 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1229

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1230 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1289

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1290 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1344

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1345 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1403

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1404 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1451

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1452 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1511

Query: 520  VFQAVKTVRRHRPQLVE 536
             FQ VKT+R  RP +V+
Sbjct: 1512 RFQTVKTLRTQRPAMVQ 1528



 Score =  115 bits (277), Expect = 8e-25
 Identities = 64/202 (31%), Positives = 97/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1352 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1409

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1410 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1466

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D F  +K LR  
Sbjct: 1467 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDRFQTVKTLRTQ 1522

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1523 RPAMVQTEDQYQLCYRAALEYL 1544



 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 78/283 (27%), Positives = 135/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 978  PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKLKNRYANV 1029

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   YIAT+ PL  T G+FW +V++   A
Sbjct: 1030 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTA 1089

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1090 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1142

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1143 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1194

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1195 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1237


>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
            phosphatase, receptor type, F protein.
          Length = 1898

 Score =  251 bits (615), Expect = 9e-66
 Identities = 156/497 (31%), Positives = 256/497 (51%), Gaps = 35/497 (7%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K  AY  TQGP  +T+ DFWRM+W++R A +VM+T+  +  +V C QYWP      ET G
Sbjct: 1407 KQNAYTATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGT--ETCG 1464

Query: 106  DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
             I V ++   ELA + +RTF L+K+      E+R + QF +  W  H  P      E+  
Sbjct: 1465 LIQVTLLDTVELATYTVRTFALHKSGSS---EKRELRQFQFMAWPDHGVP------EYPT 1515

Query: 166  XXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        NP  AGPMVVHC+ G GR+G ++ IDA LE  + E + D++G +  +R
Sbjct: 1516 PILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMR 1575

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E+QY F+++ L E   CG +  P   L   +++  Q  P   +   + E++
Sbjct: 1576 SQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFK 1635

Query: 285  QICK---QTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
             +      T RF        +   N+ KNR V ++P +  R  L   +G   +DYINA F
Sbjct: 1636 LLASSKAHTSRF-----ISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASF 1690

Query: 342  VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHS 400
            +DGY + + YIAT+ PL  +  +FW +++++    +V+L  +     ++   +WP  R S
Sbjct: 1691 LDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAER-S 1749

Query: 401  KKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGH 460
             +Y   F +D ++     N+  +I R  K    +T+   G    ++T++ FQ T WP   
Sbjct: 1750 ARY-QYFVVDPMAE---YNMPQYILREFK----VTDARDG---QSRTIRQFQFTDWP-EQ 1797

Query: 461  KVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
             VP +    ++ +  V + +++    GP+ V    G  R GV+   +  +E++   G VD
Sbjct: 1798 GVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1857

Query: 520  VFQAVKTVRRHRPQLVE 536
            +FQ VKT+R  RP +V+
Sbjct: 1858 MFQTVKTLRTQRPAMVQ 1874



 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 10/202 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            KAYI TQGP  ++  DFWRM+W+  +  IVMLTK  +  +  C QYWP   E+   Y   
Sbjct: 1698 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA--ERSARYQYF 1755

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
             V  + E  +  + +R F++     G   + R I QF +T W     P +    ++F   
Sbjct: 1756 VVDPMAEYNMPQYILREFKVTDARDG---QSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQ 1812

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                           GP+ VHC+ G GR+GV++ +   LE    E   D+F  +K LR  
Sbjct: 1813 VHKTKEQFGQD----GPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQ 1868

Query: 227  RKGLIENEEQYKFVYDTLEEHV 248
            R  +++ E+QY+  Y    E++
Sbjct: 1869 RPAMVQTEDQYQLCYRAALEYL 1890



 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 77/283 (27%), Positives = 134/283 (47%), Gaps = 25/283 (8%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
            P+++L+  +++    D +    ++ +EY+ I     +FT       +   N+ KNR   V
Sbjct: 1324 PITDLADNIERLKANDGL----KFSQEYESI-DPGQQFT---WENSNLEVNKPKNRYANV 1375

Query: 316  VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
            +  D+ R  LTS  G   +DYINA ++DGY K   Y AT+ PL  T G+FW +V++   A
Sbjct: 1376 IAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYTATQGPLPETMGDFWRMVWEQRTA 1435

Query: 376  AVVVLC-VPPKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
             VV++  +  K+  +   +WP  G  +     V  +D V    YT ++T  F ++K    
Sbjct: 1436 TVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYT-VRT--FALHK---- 1488

Query: 434  LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
                 +G  +  + ++ FQ   WP  H VP     ++  +  V+      D GP+ V   
Sbjct: 1489 -----SG-SSEKRELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNP-LDAGPMVVHCS 1540

Query: 494  DGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
             G  R G +   +A +E++     VD++  V  +R  R  +V+
Sbjct: 1541 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQ 1583


>X54130-1|CAA38065.1|  793|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 793

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 358

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 359 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 418

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 419 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 532 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 647

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 648 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 694

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 695 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 754

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 755 VKSLRLQRPHMVQTL 769



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 650

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 651 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 706

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 707 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 763

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 764 HMVQTLEQYEFCYKVVQEYI 783



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 248 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 307

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 308 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 362

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 363 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 418

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 419 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 477


>X53364-1|CAA37447.1|  793|Homo sapiens tyrosine phosphatase
           precursor protein.
          Length = 793

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 358

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 359 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 418

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 419 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 532 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 647

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 648 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 694

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 695 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 754

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 755 VKSLRLQRPHMVQTL 769



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 650

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 651 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 706

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 707 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 763

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 764 HMVQTLEQYEFCYKVVQEYI 783



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 248 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 307

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 308 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 362

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 363 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 418

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 419 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 477


>M34668-1|AAA36528.1|  802|Homo sapiens protein ( Human protein
           tyrosine phosphatase (PTPase-alpha) mRNA. ).
          Length = 802

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 310 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 367

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 368 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 427

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 428 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 541 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 656

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 657 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 703

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 704 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 763

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 764 VKSLRLQRPHMVQTL 778



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 602 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 659

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 660 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 715

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 716 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 772

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 773 HMVQTLEQYEFCYKVVQEYI 792



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 257 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 316

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 317 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 371

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 372 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 427

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 428 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 486


>BC027308-1|AAH27308.1|  793|Homo sapiens protein tyrosine
           phosphatase, receptor type, A protein.
          Length = 793

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 358

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 359 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 418

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 419 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 532 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 647

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 648 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 694

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 695 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 754

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 755 VKSLRLQRPHMVQTL 769



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 650

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 651 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 706

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 707 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 763

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 764 HMVQTLEQYEFCYKVVQEYI 783



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 248 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 307

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 308 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 362

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 363 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 418

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 419 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 477


>AL121905-6|CAC10336.1|  802|Homo sapiens protein tyrosine
           phosphatase, receptor type, A protein.
          Length = 802

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 310 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 367

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 368 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 427

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 428 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 480

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 481 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 540

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 541 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 656

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 657 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 703

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 704 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 763

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 764 VKSLRLQRPHMVQTL 778



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 602 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 659

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 660 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 715

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 716 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 772

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 773 HMVQTLEQYEFCYKVVQEYI 792



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 257 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 316

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 317 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 371

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 372 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 427

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 428 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 486


>AL121905-5|CAC10337.1|  793|Homo sapiens protein tyrosine
           phosphatase, receptor type, A protein.
          Length = 793

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 358

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 359 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 418

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 419 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 472 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 532 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 647

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 648 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 694

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 695 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 754

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 755 VKSLRLQRPHMVQTL 769



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 650

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 651 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 706

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 707 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 763

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 764 HMVQTLEQYEFCYKVVQEYI 783



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 248 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 307

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 308 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 362

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 363 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 418

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 419 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 477


>AB209702-1|BAD92939.1|  651|Homo sapiens protein tyrosine
           phosphatase, receptor type, A isoform 2 precursor
           variant protein.
          Length = 651

 Score =  238 bits (582), Expect = 9e-62
 Identities = 143/495 (28%), Positives = 260/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I V
Sbjct: 159 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRV 216

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 217 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 276

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 277 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 329

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY F+Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 330 RCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 389

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 390 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 447

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 448 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 505

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 506 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 552

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 553 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 612

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 613 VKSLRLQRPHMVQTL 627



 Score =  120 bits (290), Expect = 2e-26
 Identities = 67/200 (33%), Positives = 105/200 (52%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 451 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 508

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 509 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 564

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 565 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 621

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y  ++E++
Sbjct: 622 HMVQTLEQYEFCYKVVQEYI 641



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 62/240 (25%), Positives = 115/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +G   +DYINA F++GY +  ++IA + P
Sbjct: 106 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGP 165

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +     VS   
Sbjct: 166 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RVSVED 220

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 221 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 276

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 277 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 335


>AJ315969-1|CAC86583.1|  642|Homo sapiens tyrosine phosphatase
           epsilon protein.
          Length = 642

 Score =  237 bits (579), Expect = 2e-61
 Identities = 155/517 (29%), Positives = 260/517 (50%), Gaps = 27/517 (5%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 123 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 182

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 183 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 240

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 241 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 293

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 294 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 353

Query: 265 KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
             ++     T  ++   E +       R    +   G+   N +K R + ++P D  R  
Sbjct: 354 --QTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVI 411

Query: 325 LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VP 383
           L+  +G  +TDYINA F+DGY +   +IAT+ PL  T  +FW +++D++   +V+L  V 
Sbjct: 412 LSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWDWKSHTIVMLTEVQ 471

Query: 384 PKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVK 442
            +   +   +WP EG  S  +G + TI+ + ++  +        I   +++L +  A  +
Sbjct: 472 EREQDKCYQYWPTEG--SVTHGEI-TIE-IKNDTLSE----AISIRDFLVTLNQPQARQE 523

Query: 443 APTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGV 501
              + V+ F    WP +G  +P+    +++L+  V++ +Q+T   P+ V    G  R G 
Sbjct: 524 EQVRVVRQFHFHGWPEIG--IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGT 581

Query: 502 YCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENM 538
           + A +  +E+V   G +DVFQAVK++R  RP +V+ +
Sbjct: 582 FIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTL 618



 Score =  109 bits (262), Expect = 6e-23
 Identities = 64/201 (31%), Positives = 96/201 (47%), Gaps = 8/201 (3%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I TQGP   TV DFWRMIW  ++  IVMLT+  +  +  C QYWP   E   T+G+I++
Sbjct: 438 FIATQGPLAHTVEDFWRMIWDWKSHTIVMLTEVQEREQDKCYQYWPT--EGSVTHGEITI 495

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEE--RFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            I  +       IR F +   +     EE  R + QFH+  W     P     +      
Sbjct: 496 EIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGM----ID 551

Query: 168 XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                          P+ VHC+ G GR+G ++A+   LE  + E   DVF  +K LR  R
Sbjct: 552 LIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQR 611

Query: 228 KGLIENEEQYKFVYDTLEEHV 248
             +++  EQY+F Y  +++ +
Sbjct: 612 PHMVQTLEQYEFCYKVVQDFI 632



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 31  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 84

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 85  --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 142

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 143 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 201

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 202 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 252

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 253 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 311

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 312 IRNQRPQMVQ 321


>X54134-1|CAA38069.1|  700|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 700

 Score =  235 bits (575), Expect = 7e-61
 Identities = 154/517 (29%), Positives = 260/517 (50%), Gaps = 27/517 (5%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 181 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 240

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 241 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 298

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 299 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 351

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 352 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 411

Query: 265 KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
             ++     T  ++   E +       R    +   G+   N +K R + ++P D  R  
Sbjct: 412 --QTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVI 469

Query: 325 LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VP 383
           L+  +G  +TDYINA F+DGY +   +IAT+ PL  T  +FW ++++++   +V+L  V 
Sbjct: 470 LSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQ 529

Query: 384 PKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVK 442
            +   +   +WP EG  S  +G + TI+ + ++  +        I   +++L +  A  +
Sbjct: 530 EREQDKCYQYWPTEG--SVTHGEI-TIE-IKNDTLSE----AISIRDFLVTLNQPQARQE 581

Query: 443 APTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGV 501
              + V+ F    WP +G  +P+    +++L+  V++ +Q+T   P+ V    G  R G 
Sbjct: 582 EQVRVVRQFHFHGWPEIG--IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGT 639

Query: 502 YCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENM 538
           + A +  +E+V   G +DVFQAVK++R  RP +V+ +
Sbjct: 640 FIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTL 676



 Score =  110 bits (264), Expect = 3e-23
 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 8/201 (3%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I TQGP   TV DFWRMIW+ ++  IVMLT+  +  +  C QYWP   E   T+G+I++
Sbjct: 496 FIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPT--EGSVTHGEITI 553

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEE--RFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            I  +       IR F +   +     EE  R + QFH+  W     P     +      
Sbjct: 554 EIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGM----ID 609

Query: 168 XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                          P+ VHC+ G GR+G ++A+   LE  + E   DVF  +K LR  R
Sbjct: 610 LIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQR 669

Query: 228 KGLIENEEQYKFVYDTLEEHV 248
             +++  EQY+F Y  +++ +
Sbjct: 670 PHMVQTLEQYEFCYKVVQDFI 690



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 89  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 142

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 143 --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 200

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 201 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 259

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 260 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 310

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 311 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 369

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 370 IRNQRPQMVQ 379


>BC050062-1|AAH50062.1|  700|Homo sapiens PTPRE protein protein.
          Length = 700

 Score =  235 bits (575), Expect = 7e-61
 Identities = 154/517 (29%), Positives = 260/517 (50%), Gaps = 27/517 (5%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 181 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 240

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 241 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 298

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 299 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 351

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 352 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 411

Query: 265 KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
             ++     T  ++   E +       R    +   G+   N +K R + ++P D  R  
Sbjct: 412 --QTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVI 469

Query: 325 LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VP 383
           L+  +G  +TDYINA F+DGY +   +IAT+ PL  T  +FW ++++++   +V+L  V 
Sbjct: 470 LSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQ 529

Query: 384 PKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVK 442
            +   +   +WP EG  S  +G + TI+ + ++  +        I   +++L +  A  +
Sbjct: 530 EREQDKCYQYWPTEG--SVTHGEI-TIE-IKNDTLSE----AISIRDFLVTLNQPQARQE 581

Query: 443 APTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGV 501
              + V+ F    WP +G  +P+    +++L+  V++ +Q+T   P+ V    G  R G 
Sbjct: 582 EQVRVVRQFHFHGWPEIG--IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGT 639

Query: 502 YCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENM 538
           + A +  +E+V   G +DVFQAVK++R  RP +V+ +
Sbjct: 640 FIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTL 676



 Score =  110 bits (264), Expect = 3e-23
 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 8/201 (3%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I TQGP   TV DFWRMIW+ ++  IVMLT+  +  +  C QYWP   E   T+G+I++
Sbjct: 496 FIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPT--EGSVTHGEITI 553

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEE--RFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            I  +       IR F +   +     EE  R + QFH+  W     P     +      
Sbjct: 554 EIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGM----ID 609

Query: 168 XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                          P+ VHC+ G GR+G ++A+   LE  + E   DVF  +K LR  R
Sbjct: 610 LIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQR 669

Query: 228 KGLIENEEQYKFVYDTLEEHV 248
             +++  EQY+F Y  +++ +
Sbjct: 670 PHMVQTLEQYEFCYKVVQDFI 690



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 89  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 142

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 143 --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 200

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 201 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 259

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 260 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 310

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 311 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 369

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 370 IRNQRPQMVQ 379


>AL390236-6|CAH73174.1|  642|Homo sapiens protein tyrosine
           phosphatase, receptor type, E protein.
          Length = 642

 Score =  235 bits (575), Expect = 7e-61
 Identities = 154/517 (29%), Positives = 260/517 (50%), Gaps = 27/517 (5%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 123 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 182

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 183 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 240

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 241 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 293

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 294 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 353

Query: 265 KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
             ++     T  ++   E +       R    +   G+   N +K R + ++P D  R  
Sbjct: 354 --QTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVI 411

Query: 325 LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VP 383
           L+  +G  +TDYINA F+DGY +   +IAT+ PL  T  +FW ++++++   +V+L  V 
Sbjct: 412 LSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQ 471

Query: 384 PKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVK 442
            +   +   +WP EG  S  +G + TI+ + ++  +        I   +++L +  A  +
Sbjct: 472 EREQDKCYQYWPTEG--SVTHGEI-TIE-IKNDTLSE----AISIRDFLVTLNQPQARQE 523

Query: 443 APTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGV 501
              + V+ F    WP +G  +P+    +++L+  V++ +Q+T   P+ V    G  R G 
Sbjct: 524 EQVRVVRQFHFHGWPEIG--IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGT 581

Query: 502 YCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENM 538
           + A +  +E+V   G +DVFQAVK++R  RP +V+ +
Sbjct: 582 FIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTL 618



 Score =  110 bits (264), Expect = 3e-23
 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 8/201 (3%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I TQGP   TV DFWRMIW+ ++  IVMLT+  +  +  C QYWP   E   T+G+I++
Sbjct: 438 FIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPT--EGSVTHGEITI 495

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEE--RFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            I  +       IR F +   +     EE  R + QFH+  W     P     +      
Sbjct: 496 EIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGM----ID 551

Query: 168 XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                          P+ VHC+ G GR+G ++A+   LE  + E   DVF  +K LR  R
Sbjct: 552 LIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQR 611

Query: 228 KGLIENEEQYKFVYDTLEEHV 248
             +++  EQY+F Y  +++ +
Sbjct: 612 PHMVQTLEQYEFCYKVVQDFI 632



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 31  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 84

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 85  --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 142

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 143 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 201

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 202 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 252

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 253 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 311

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 312 IRNQRPQMVQ 321


>AL390236-5|CAH73173.1|  700|Homo sapiens protein tyrosine
           phosphatase, receptor type, E protein.
          Length = 700

 Score =  235 bits (575), Expect = 7e-61
 Identities = 154/517 (29%), Positives = 260/517 (50%), Gaps = 27/517 (5%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 181 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 240

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 241 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 298

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 299 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 351

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 352 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 411

Query: 265 KQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPY 324
             ++     T  ++   E +       R    +   G+   N +K R + ++P D  R  
Sbjct: 412 --QTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVI 469

Query: 325 LTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VP 383
           L+  +G  +TDYINA F+DGY +   +IAT+ PL  T  +FW ++++++   +V+L  V 
Sbjct: 470 LSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQ 529

Query: 384 PKNSQQYPPFWP-EGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVK 442
            +   +   +WP EG  S  +G + TI+ + ++  +        I   +++L +  A  +
Sbjct: 530 EREQDKCYQYWPTEG--SVTHGEI-TIE-IKNDTLSE----AISIRDFLVTLNQPQARQE 581

Query: 443 APTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGV 501
              + V+ F    WP +G  +P+    +++L+  V++ +Q+T   P+ V    G  R G 
Sbjct: 582 EQVRVVRQFHFHGWPEIG--IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGT 639

Query: 502 YCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENM 538
           + A +  +E+V   G +DVFQAVK++R  RP +V+ +
Sbjct: 640 FIALSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTL 676



 Score =  110 bits (264), Expect = 3e-23
 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 8/201 (3%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I TQGP   TV DFWRMIW+ ++  IVMLT+  +  +  C QYWP   E   T+G+I++
Sbjct: 496 FIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPT--EGSVTHGEITI 553

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEE--RFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            I  +       IR F +   +     EE  R + QFH+  W     P     +      
Sbjct: 554 EIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGIPAEGKGM----ID 609

Query: 168 XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                          P+ VHC+ G GR+G ++A+   LE  + E   DVF  +K LR  R
Sbjct: 610 LIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQAVKSLRLQR 669

Query: 228 KGLIENEEQYKFVYDTLEEHV 248
             +++  EQY+F Y  +++ +
Sbjct: 670 PHMVQTLEQYEFCYKVVQDFI 690



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 89  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 142

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 143 --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 200

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 201 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 259

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 260 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 310

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 311 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 369

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 370 IRNQRPQMVQ 379


>X54890-1|CAA38662.1|  793|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 793

 Score =  233 bits (570), Expect = 3e-60
 Identities = 141/495 (28%), Positives = 258/495 (52%), Gaps = 32/495 (6%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I  QGP E+TV DFWRMIW++  A IVM+T   +  +  C QYWP   +   TYG+I  
Sbjct: 301 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD--QGCWTYGNIRA 358

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIE-ERFILQFHYTQWHSHTCPFSN-ALLEFXXXX 167
            +     L ++ +R F + +       + +R I QFH+T W     PF+   +L+F    
Sbjct: 359 SVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKV 418

Query: 168 XXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                     NP  AG +VVHC+ G GR+G ++ IDA L++   E   DV+G + ++R  
Sbjct: 419 KAC-------NPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQ 471

Query: 227 RKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQI 286
           R  +++ + QY  +Y  L EH + G +   V+ L   L++   + P T  N  ++E++++
Sbjct: 472 RCQMVQTDMQYVSIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKL 531

Query: 287 CKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT 346
              + +        G+   N +KNR + ++P +  R  +   +G   TDY+NA F+DGY 
Sbjct: 532 --TSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589

Query: 347 KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP-EGRHSKKYG 404
           +   YIA++ PL+ T  +FW ++++++  ++V+L  +  +  ++   +WP +G  S  YG
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVS--YG 647

Query: 405 PVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVP 463
            + T++        +     + +   +++ T      +  ++ ++ F    WP +G  +P
Sbjct: 648 DI-TVELKKEEECES-----YTVRDLLVTNTR-----ENKSRQIRQFHFHGWPEVG--IP 694

Query: 464 SSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQA 523
           S    ++ ++  V++ +Q++   P+ V    G  R G +CA +  +E+V   G +DVFQ 
Sbjct: 695 SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQT 754

Query: 524 VKTVRRHRPQLVENM 538
           VK++R  RP +V+ +
Sbjct: 755 VKSLRLQRPHMVQTL 769



 Score =  122 bits (293), Expect = 1e-26
 Identities = 67/200 (33%), Positives = 106/200 (53%), Gaps = 9/200 (4%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           +YI +QGP   T+ DFWRMIW+ ++ +IVMLT+  +  +  C QYWP   +   +YGDI+
Sbjct: 593 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYGDIT 650

Query: 109 VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXX 168
           V + +EEE  ++ +R   +  T +    + R I QFH+  W     P S+          
Sbjct: 651 VELKKEEECESYTVRDLLVTNTREN---KSRQIRQFHFHGWPEVGIP-SDGKGMISIIAA 706

Query: 169 XXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRK 228
                    N    P+ VHC+ G GR+G + A+   LE  + E   DVF  +K LR  R 
Sbjct: 707 VQKQQQQSGNH---PITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRP 763

Query: 229 GLIENEEQYKFVYDTLEEHV 248
            +++  EQY+F Y+ ++E++
Sbjct: 764 HMVQTLEQYEFCYEVVQEYI 783



 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 60/240 (25%), Positives = 113/240 (47%), Gaps = 11/240 (4%)

Query: 298 CAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWP 357
           C    + +N+EKNR V ++P D+ R +LT  +    +DYINA F++GY +  ++IA + P
Sbjct: 248 CEAASKEENKEKNRYVNILPYDHSRVHLTPVEEVPDSDYINASFINGYQEKNKFIAAQGP 307

Query: 358 LMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNH 416
              T  +FW ++++   A +V++  +  +   +   +WP+ +    YG +      S   
Sbjct: 308 KEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNI----RASVED 362

Query: 417 YTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMV 476
            T +    + + K  I     M   K P + +  F  T WP    VP +   +++ +  V
Sbjct: 363 VTVLVD--YTVRKFCIQQVGDMTNRK-PQRLITQFHFTSWP-DFGVPFTPIGMLKFLKKV 418

Query: 477 ERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +    +   G + V    G  R G +   +A ++ +    +VDV+  V  +R  R Q+V+
Sbjct: 419 KACNPQY-AGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQ 477


>U46116-1|AAC50439.1| 1445|Homo sapiens receptor tyrosine phosphatase
            gamma protein.
          Length = 1445

 Score =  222 bits (543), Expect = 5e-57
 Identities = 151/496 (30%), Positives = 235/496 (47%), Gaps = 30/496 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K KAYI TQGP + T  DFWRMIW++    IVM+T   +  +  C QYWP   E  E YG
Sbjct: 917  KAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPT--ENSEEYG 974

Query: 106  DISVGIVQEEELANFFIRTF--RLYKTEKGVV------IEERFILQFHYTQWHSHTCP-F 156
            +I V +   +  A + +R F  R  K +KG          ER ++Q+HYTQW     P +
Sbjct: 975  NIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEY 1034

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
            +  +L F               P  GP++VHC+ G GR+G Y+ ID+ L+  +++ + +V
Sbjct: 1035 ALPVLTFVRRSSAARM------PETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNV 1088

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKL 276
             G LK +R  R  L++ EEQY F++D L E ++   +    ++L   +        V   
Sbjct: 1089 LGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYV-NSILIPGVGGK 1147

Query: 277  NEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDY 336
               +K+++ + +   ++   +C    +  N+EKNR+  VVP +  R  L    G   TDY
Sbjct: 1148 TRLEKQFKLVTQCNAKYV--ECFSAQKECNKEKNRNSXVVPSERARVGLAPLPGMKGTDY 1205

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPE 396
            INA ++ GY +  E+I T+ PL  T  +FW +++D+    +V+L      ++    +WP 
Sbjct: 1206 INASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWP- 1264

Query: 397  GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCW 456
             R        FT+  +S +           I+  I+  T+           V+ FQ   W
Sbjct: 1265 SREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQ-----DDYVLEVRHFQCPKW 1319

Query: 457  PMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG 516
            P      SST    EL+N+++      D GP  V    G   AG+ CA     +Q+    
Sbjct: 1320 PNPDAPISST---FELINVIKEEALTRD-GPTIVHDEYGAVSAGMLCALTTLSQQLENEN 1375

Query: 517  EVDVFQAVKTVRRHRP 532
             VDVFQ  K +   RP
Sbjct: 1376 AVDVFQVAKMINLMRP 1391



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 69/264 (26%), Positives = 126/264 (47%), Gaps = 13/264 (4%)

Query: 279  YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG--NSFTDY 336
            + ++++++ + T    I      H  +N+ KNR + ++  D+ R  L    G  +  +DY
Sbjct: 848  FSEDFEEVQRCTADMNITAEHSNHP-ENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDY 906

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP 395
            INA +VDGY K + YIAT+ PL  T  +FW ++++     +V++  +  K  ++   +WP
Sbjct: 907  INANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWP 966

Query: 396  EGRHSKKYGPVF-TIDHVS-HNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQL 453
               +S++YG +  T+     H  YT ++ +  R N K+    +     +   + V  +  
Sbjct: 967  T-ENSEEYGNIIVTLKSTKIHACYT-VRRFSIR-NTKVKKGQKGNPKGRQNERVVIQYHY 1023

Query: 454  TCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQV 512
            T WP MG  VP     ++  +      R   + GPV V    G  R G Y   ++ ++Q+
Sbjct: 1024 TQWPDMG--VPEYALPVLTFVRRSSAARM-PETGPVLVHCSAGVGRTGTYIVIDSMLQQI 1080

Query: 513  IKHGEVDVFQAVKTVRRHRPQLVE 536
                 V+V   +K +R  R  LV+
Sbjct: 1081 KDKSTVNVLGFLKHIRTQRNYLVQ 1104



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 56/197 (28%), Positives = 84/197 (42%), Gaps = 17/197 (8%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I+TQ P   T  DFWRMIW   A  IVML       +   V YWP ++E+       +V
Sbjct: 1220 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWP-SREESMNCEAFTV 1277

Query: 110  GIVQEEELA-----NFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
             ++ ++ L         I  F L  T+   V+E R    F   +W +   P S+   E  
Sbjct: 1278 TLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVR---HFQCPKWPNPDAPISSTF-ELI 1333

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                             GP +VH   G   +G+  A+    +  E E++ DVF   K + 
Sbjct: 1334 NVIKEEALTRD------GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMIN 1387

Query: 225  ESRKGLIENEEQYKFVY 241
              R G+  + EQY+F+Y
Sbjct: 1388 LMRPGVFTDIEQYQFIY 1404


>X54132-1|CAA38067.1|  610|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 610

 Score =  222 bits (542), Expect = 7e-57
 Identities = 151/496 (30%), Positives = 235/496 (47%), Gaps = 30/496 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KAYI TQGP + T  DFWRMIW++    IVM+T   +  +  C QYWP   E  E YG
Sbjct: 82  KAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPT--ENSEEYG 139

Query: 106 DISVGIVQEEELANFFIRTF--RLYKTEKGVV------IEERFILQFHYTQWHSHTCP-F 156
           +I V +   +  A + +R F  R  K +KG          ER ++Q+HYTQW     P +
Sbjct: 140 NIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEY 199

Query: 157 SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
           +  +L F               P  GP++VHC+ G GR+G Y+ ID+ L+  +++ + +V
Sbjct: 200 ALPVLTFVRRSSAARM------PETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNV 253

Query: 217 FGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKL 276
            G LK +R  R  L++ EEQY F++D L E ++   +    ++L   +        V   
Sbjct: 254 LGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYV-NSILIPGVGGK 312

Query: 277 NEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDY 336
              +K+++ + +   ++   +C    +  N+EKNR+  VVP +  R  L    G   TDY
Sbjct: 313 TRLEKQFKLVTQCNAKYV--ECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDY 370

Query: 337 INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPE 396
           INA ++ GY +  E+I T+ PL  T  +FW +++D+    +V+L      ++    +WP 
Sbjct: 371 INASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWP- 429

Query: 397 GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCW 456
            R        FT+  +S +           I+  I+  T+           V+ FQ   W
Sbjct: 430 SREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQ-----DDYVLEVRHFQCPKW 484

Query: 457 PMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG 516
           P      SST    EL+N+++      D GP  V    G   AG+ CA     +Q+    
Sbjct: 485 PNPDAPISST---FELINVIKEEALTRD-GPTIVHDEYGAVSAGMLCALTTLSQQLENEN 540

Query: 517 EVDVFQAVKTVRRHRP 532
            VDVFQ  K +   RP
Sbjct: 541 AVDVFQVAKMINLMRP 556



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 69/264 (26%), Positives = 126/264 (47%), Gaps = 13/264 (4%)

Query: 279 YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG--NSFTDY 336
           + ++++++ + T    I      H  +N+ KNR + ++  D+ R  L    G  +  +DY
Sbjct: 13  FSEDFEEVQRCTADMNITAEHSNHP-ENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDY 71

Query: 337 INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP 395
           INA +VDGY K + YIAT+ PL  T  +FW ++++     +V++  +  K  ++   +WP
Sbjct: 72  INANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWP 131

Query: 396 EGRHSKKYGPVF-TIDHVS-HNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQL 453
              +S++YG +  T+     H  YT ++ +  R N K+    +     +   + V  +  
Sbjct: 132 T-ENSEEYGNIIVTLKSTKIHACYT-VRRFSIR-NTKVKKGQKGNPKGRQNERVVIQYHY 188

Query: 454 TCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQV 512
           T WP MG  VP     ++  +      R   + GPV V    G  R G Y   ++ ++Q+
Sbjct: 189 TQWPDMG--VPEYALPVLTFVRRSSAARM-PETGPVLVHCSAGVGRTGTYIVIDSMLQQI 245

Query: 513 IKHGEVDVFQAVKTVRRHRPQLVE 536
                V+V   +K +R  R  LV+
Sbjct: 246 KDKSTVNVLGFLKHIRTQRNYLVQ 269



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 56/200 (28%), Positives = 85/200 (42%), Gaps = 17/200 (8%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           +I+TQ P   T  DFWRMIW   A  IVML       +   V YWP ++E+       +V
Sbjct: 385 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWP-SREESMNCEAFTV 442

Query: 110 GIVQEEELA-----NFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            ++ ++ L         I  F L  T+   V+E R    F   +W +   P S+   E  
Sbjct: 443 TLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVR---HFQCPKWPNPDAPISSTF-ELI 498

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                            GP +VH   G   +G+  A+    +  E E++ DVF   K + 
Sbjct: 499 NVIKEEALTRD------GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMIN 552

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+  + EQY+F+Y  +
Sbjct: 553 LMRPGVFTDIEQYQFIYKAM 572


>L09247-1|AAA60224.1| 1445|Homo sapiens receptor-type protein tyrosine
            phosphatase gamma protein.
          Length = 1445

 Score =  222 bits (542), Expect = 7e-57
 Identities = 151/496 (30%), Positives = 235/496 (47%), Gaps = 30/496 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K KAYI TQGP + T  DFWRMIW++    IVM+T   +  +  C QYWP   E  E YG
Sbjct: 917  KAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPT--ENSEEYG 974

Query: 106  DISVGIVQEEELANFFIRTF--RLYKTEKGVV------IEERFILQFHYTQWHSHTCP-F 156
            +I V +   +  A + +R F  R  K +KG          ER ++Q+HYTQW     P +
Sbjct: 975  NIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEY 1034

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
            +  +L F               P  GP++VHC+ G GR+G Y+ ID+ L+  +++ + +V
Sbjct: 1035 ALPVLTFVRRSSAARM------PETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNV 1088

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKL 276
             G LK +R  R  L++ EEQY F++D L E ++   +    ++L   +        V   
Sbjct: 1089 LGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYV-NSILIPGVGGK 1147

Query: 277  NEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDY 336
               +K+++ + +   ++   +C    +  N+EKNR+  VVP +  R  L    G   TDY
Sbjct: 1148 TRLEKQFKLVTQCNAKYV--ECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDY 1205

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPE 396
            INA ++ GY +  E+I T+ PL  T  +FW +++D+    +V+L      ++    +WP 
Sbjct: 1206 INASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWP- 1264

Query: 397  GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCW 456
             R        FT+  +S +           I+  I+  T+           V+ FQ   W
Sbjct: 1265 SREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQ-----DDYVLEVRHFQCPKW 1319

Query: 457  PMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG 516
            P      SST    EL+N+++      D GP  V    G   AG+ CA     +Q+    
Sbjct: 1320 PNPDAPISST---FELINVIKEEALTRD-GPTIVHDEYGAVSAGMLCALTTLSQQLENEN 1375

Query: 517  EVDVFQAVKTVRRHRP 532
             VDVFQ  K +   RP
Sbjct: 1376 AVDVFQVAKMINLMRP 1391



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 69/264 (26%), Positives = 126/264 (47%), Gaps = 13/264 (4%)

Query: 279  YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG--NSFTDY 336
            + ++++++ + T    I      H  +N+ KNR + ++  D+ R  L    G  +  +DY
Sbjct: 848  FSEDFEEVQRCTADMNITAEHSNHP-ENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDY 906

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP 395
            INA +VDGY K + YIAT+ PL  T  +FW ++++     +V++  +  K  ++   +WP
Sbjct: 907  INANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWP 966

Query: 396  EGRHSKKYGPVF-TIDHVS-HNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQL 453
               +S++YG +  T+     H  YT ++ +  R N K+    +     +   + V  +  
Sbjct: 967  T-ENSEEYGNIIVTLKSTKIHACYT-VRRFSIR-NTKVKKGQKGNPKGRQNERVVIQYHY 1023

Query: 454  TCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQV 512
            T WP MG  VP     ++  +      R   + GPV V    G  R G Y   ++ ++Q+
Sbjct: 1024 TQWPDMG--VPEYALPVLTFVRRSSAARM-PETGPVLVHCSAGVGRTGTYIVIDSMLQQI 1080

Query: 513  IKHGEVDVFQAVKTVRRHRPQLVE 536
                 V+V   +K +R  R  LV+
Sbjct: 1081 KDKSTVNVLGFLKHIRTQRNYLVQ 1104



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 56/197 (28%), Positives = 84/197 (42%), Gaps = 17/197 (8%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I+TQ P   T  DFWRMIW   A  IVML       +   V YWP ++E+       +V
Sbjct: 1220 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWP-SREESMNCEAFTV 1277

Query: 110  GIVQEEELA-----NFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
             ++ ++ L         I  F L  T+   V+E R    F   +W +   P S+   E  
Sbjct: 1278 TLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVR---HFQCPKWPNPDAPISSTF-ELI 1333

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                             GP +VH   G   +G+  A+    +  E E++ DVF   K + 
Sbjct: 1334 NVIKEEALTRD------GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMIN 1387

Query: 225  ESRKGLIENEEQYKFVY 241
              R G+  + EQY+F+Y
Sbjct: 1388 LMRPGVFTDIEQYQFIY 1404


>AB209871-1|BAD93108.1| 1530|Homo sapiens protein tyrosine
            phosphatase, receptor type, G precursor variant protein.
          Length = 1530

 Score =  222 bits (542), Expect = 7e-57
 Identities = 151/496 (30%), Positives = 235/496 (47%), Gaps = 30/496 (6%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            K KAYI TQGP + T  DFWRMIW++    IVM+T   +  +  C QYWP   E  E YG
Sbjct: 1002 KAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPT--ENSEEYG 1059

Query: 106  DISVGIVQEEELANFFIRTF--RLYKTEKGVV------IEERFILQFHYTQWHSHTCP-F 156
            +I V +   +  A + +R F  R  K +KG          ER ++Q+HYTQW     P +
Sbjct: 1060 NIIVTLKSTKIHACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEY 1119

Query: 157  SNALLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDV 216
            +  +L F               P  GP++VHC+ G GR+G Y+ ID+ L+  +++ + +V
Sbjct: 1120 ALPVLTFVRRSSAARM------PETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNV 1173

Query: 217  FGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKL 276
             G LK +R  R  L++ EEQY F++D L E ++   +    ++L   +        V   
Sbjct: 1174 LGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSSNQLHSYV-NSILIPGVGGK 1232

Query: 277  NEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDY 336
               +K+++ + +   ++   +C    +  N+EKNR+  VVP +  R  L    G   TDY
Sbjct: 1233 TRLEKQFKLVTQCNAKYV--ECFSAQKECNKEKNRNSSVVPSERARVGLAPLPGMKGTDY 1290

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPE 396
            INA ++ GY +  E+I T+ PL  T  +FW +++D+    +V+L      ++    +WP 
Sbjct: 1291 INASYIMGYYRSNEFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWP- 1349

Query: 397  GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCW 456
             R        FT+  +S +           I+  I+  T+           V+ FQ   W
Sbjct: 1350 SREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQ-----DDYVLEVRHFQCPKW 1404

Query: 457  PMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG 516
            P      SST    EL+N+++      D GP  V    G   AG+ CA     +Q+    
Sbjct: 1405 PNPDAPISST---FELINVIKEEALTRD-GPTIVHDEYGAVSAGMLCALTTLSQQLENEN 1460

Query: 517  EVDVFQAVKTVRRHRP 532
             VDVFQ  K +   RP
Sbjct: 1461 AVDVFQVAKMINLMRP 1476



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 69/264 (26%), Positives = 126/264 (47%), Gaps = 13/264 (4%)

Query: 279  YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG--NSFTDY 336
            + ++++++ + T    I      H  +N+ KNR + ++  D+ R  L    G  +  +DY
Sbjct: 933  FSEDFEEVQRCTADMNITAEHSNHP-ENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDY 991

Query: 337  INAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWP 395
            INA +VDGY K + YIAT+ PL  T  +FW ++++     +V++  +  K  ++   +WP
Sbjct: 992  INANYVDGYNKAKAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWP 1051

Query: 396  EGRHSKKYGPVF-TIDHVS-HNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQL 453
               +S++YG +  T+     H  YT ++ +  R N K+    +     +   + V  +  
Sbjct: 1052 T-ENSEEYGNIIVTLKSTKIHACYT-VRRFSIR-NTKVKKGQKGNPKGRQNERVVIQYHY 1108

Query: 454  TCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQV 512
            T WP MG  VP     ++  +      R   + GPV V    G  R G Y   ++ ++Q+
Sbjct: 1109 TQWPDMG--VPEYALPVLTFVRRSSAARM-PETGPVLVHCSAGVGRTGTYIVIDSMLQQI 1165

Query: 513  IKHGEVDVFQAVKTVRRHRPQLVE 536
                 V+V   +K +R  R  LV+
Sbjct: 1166 KDKSTVNVLGFLKHIRTQRNYLVQ 1189



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 56/200 (28%), Positives = 85/200 (42%), Gaps = 17/200 (8%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I+TQ P   T  DFWRMIW   A  IVML       +   V YWP ++E+       +V
Sbjct: 1305 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWP-SREESMNCEAFTV 1362

Query: 110  GIVQEEELA-----NFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
             ++ ++ L         I  F L  T+   V+E R    F   +W +   P S+   E  
Sbjct: 1363 TLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVR---HFQCPKWPNPDAPISSTF-ELI 1418

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                             GP +VH   G   +G+  A+    +  E E++ DVF   K + 
Sbjct: 1419 NVIKEEALTRD------GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMIN 1472

Query: 225  ESRKGLIENEEQYKFVYDTL 244
              R G+  + EQY+F+Y  +
Sbjct: 1473 LMRPGVFTDIEQYQFIYKAM 1492


>M93426-1|AAA60225.1| 2314|Homo sapiens protein tyrosine phosphatase
            zeta-polypeptide protein.
          Length = 2314

 Score =  221 bits (540), Expect = 1e-56
 Identities = 149/493 (30%), Positives = 233/493 (47%), Gaps = 28/493 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +PKAYI  QGP + T  DFWRMIW+     IVM+T   +  +  C QYWP   +  E YG
Sbjct: 1792 RPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPA--DGSEEYG 1849

Query: 106  DISVGIVQEEELANFFIRTFRLYKTE--KGVVIEE---RFILQFHYTQWHSHTCP-FSNA 159
            +  V     + LA + +R F L  T+  KG        R + Q+HYTQW     P +S  
Sbjct: 1850 NFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLP 1909

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
            +L F                A GP+VVHC+ G GR+G Y+ +D+ L+  + E + ++FG 
Sbjct: 1910 VLTFVRKAAYAKRH------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGF 1963

Query: 220  LKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEY 279
            LK +R  R  L++ EEQY F++DTL E ++   +    S +   +       P  K  + 
Sbjct: 1964 LKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGK-TKL 2022

Query: 280  QKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINA 339
            +K++Q + +        D +   +  NREKNR   ++P +  R  ++S  G   TDYINA
Sbjct: 2023 EKQFQLLSQS--NIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINA 2079

Query: 340  VFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRH 399
             ++ GY +  E+I T+ PL+ T  +FW +++D+    VV++      ++    +WP  + 
Sbjct: 2080 SYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFVYWP-NKD 2138

Query: 400  SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
                   F +  ++  H       +    K II    L A        V+ FQ   WP  
Sbjct: 2139 EPINCESFKVTLMAEEH-----KCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWP-- 2191

Query: 460  HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
                S  +   EL+++++      D GP+ V    G   AG +CA    + Q+ K   VD
Sbjct: 2192 -NPDSPISKTFELISVIKEEAANRD-GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVD 2249

Query: 520  VFQAVKTVRRHRP 532
            V+Q  K +   RP
Sbjct: 2250 VYQVAKMINLMRP 2262



 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 79/287 (27%), Positives = 135/287 (47%), Gaps = 15/287 (5%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKE-YQQICKQTPRFTIGDCAGGHRGDNREKNRDVL 314
            P+    + +         T+  E  KE YQ++   T    I   +  H  DN+ KNR + 
Sbjct: 1699 PIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHP-DNKHKNRYIN 1757

Query: 315  VVPPDNFRPYLTSF--QGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDY 372
            +V  D+ R  L     +    TDYINA +VDGY +P+ YIA + PL  T  +FW +++++
Sbjct: 1758 IVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEH 1817

Query: 373  ECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGP-VFTIDHVSHNHYTNIKTWIFRINKK 430
                +V++  +  K  ++   +WP    S++YG  + T   V    Y  ++ +  R N K
Sbjct: 1818 NVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFLVTQKSVQVLAYYTVRNFTLR-NTK 1875

Query: 431  IISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVC 489
            I   ++   G +   + V  +  T WP MG  VP  +  ++  +     + +R   GPV 
Sbjct: 1876 IKKGSQ--KG-RPSGRVVTQYHYTQWPDMG--VPEYSLPVLTFVRKA-AYAKRHAVGPVV 1929

Query: 490  VVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            V    G  R G Y   ++ ++Q+   G V++F  +K +R  R  LV+
Sbjct: 1930 VHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQ 1976



 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 60/200 (30%), Positives = 91/200 (45%), Gaps = 17/200 (8%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I+TQ P   T+ DFWRMIW   A  +VM+    +  +   V YWP NK++        V
Sbjct: 2091 FIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWP-NKDEPINCESFKV 2148

Query: 110  GIVQEEE--LAN---FFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
             ++ EE   L+N     I+ F L  T+   V+E R    F   +W +   P S    E  
Sbjct: 2149 TLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVR---HFQCPKWPNPDSPISKTF-ELI 2204

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                             GPM+VH   GG  +G + A+   +   E+E+S DV+   K + 
Sbjct: 2205 SVIKEEAANRD------GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMIN 2258

Query: 225  ESRKGLIENEEQYKFVYDTL 244
              R G+  + EQY+F+Y  +
Sbjct: 2259 LMRPGVFADIEQYQFLYKVI 2278


>AC006020-1|AAF03527.1| 1648|Homo sapiens WUGSC:H_DJ1049N15.1 protein.
          Length = 1648

 Score =  221 bits (540), Expect = 1e-56
 Identities = 149/493 (30%), Positives = 233/493 (47%), Gaps = 28/493 (5%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +PKAYI  QGP + T  DFWRMIW+     IVM+T   +  +  C QYWP   +  E YG
Sbjct: 1126 RPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPA--DGSEEYG 1183

Query: 106  DISVGIVQEEELANFFIRTFRLYKTE--KGVVIEE---RFILQFHYTQWHSHTCP-FSNA 159
            +  V     + LA + +R F L  T+  KG        R + Q+HYTQW     P +S  
Sbjct: 1184 NFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLP 1243

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
            +L F                A GP+VVHC+ G GR+G Y+ +D+ L+  + E + ++FG 
Sbjct: 1244 VLTFVRKAAYAKRH------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGF 1297

Query: 220  LKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEY 279
            LK +R  R  L++ EEQY F++DTL E ++   +    S +   +       P  K  + 
Sbjct: 1298 LKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGK-TKL 1356

Query: 280  QKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINA 339
            +K++Q + +        D +   +  NREKNR   ++P +  R  ++S  G   TDYINA
Sbjct: 1357 EKQFQLLSQS--NIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINA 1413

Query: 340  VFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRH 399
             ++ GY +  E+I T+ PL+ T  +FW +++D+    VV++      ++    +WP  + 
Sbjct: 1414 SYIMGYYQSNEFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFVYWP-NKD 1472

Query: 400  SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
                   F +  ++  H       +    K II    L A        V+ FQ   WP  
Sbjct: 1473 EPINCESFKVTLMAEEH-----KCLSNEEKLIIQDFILEATQDDYVLEVRHFQCPKWP-- 1525

Query: 460  HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
                S  +   EL+++++      D GP+ V    G   AG +CA    + Q+ K   VD
Sbjct: 1526 -NPDSPISKTFELISVIKEEAANRD-GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVD 1583

Query: 520  VFQAVKTVRRHRP 532
            V+Q  K +   RP
Sbjct: 1584 VYQVAKMINLMRP 1596



 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 79/287 (27%), Positives = 135/287 (47%), Gaps = 15/287 (5%)

Query: 256  PVSELSQRLKQKSQRDPVTKLNEYQKE-YQQICKQTPRFTIGDCAGGHRGDNREKNRDVL 314
            P+    + +         T+  E  KE YQ++   T    I   +  H  DN+ KNR + 
Sbjct: 1033 PIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHP-DNKHKNRYIN 1091

Query: 315  VVPPDNFRPYLTSF--QGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDY 372
            +V  D+ R  L     +    TDYINA +VDGY +P+ YIA + PL  T  +FW +++++
Sbjct: 1092 IVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEH 1151

Query: 373  ECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGP-VFTIDHVSHNHYTNIKTWIFRINKK 430
                +V++  +  K  ++   +WP    S++YG  + T   V    Y  ++ +  R N K
Sbjct: 1152 NVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFLVTQKSVQVLAYYTVRNFTLR-NTK 1209

Query: 431  IISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVC 489
            I   ++   G +   + V  +  T WP MG  VP  +  ++  +     + +R   GPV 
Sbjct: 1210 IKKGSQ--KG-RPSGRVVTQYHYTQWPDMG--VPEYSLPVLTFVRKA-AYAKRHAVGPVV 1263

Query: 490  VVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            V    G  R G Y   ++ ++Q+   G V++F  +K +R  R  LV+
Sbjct: 1264 VHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQ 1310



 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 60/200 (30%), Positives = 91/200 (45%), Gaps = 17/200 (8%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
            +I+TQ P   T+ DFWRMIW   A  +VM+    +  +   V YWP NK++        V
Sbjct: 1425 FIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWP-NKDEPINCESFKV 1482

Query: 110  GIVQEEE--LAN---FFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
             ++ EE   L+N     I+ F L  T+   V+E R    F   +W +   P S    E  
Sbjct: 1483 TLMAEEHKCLSNEEKLIIQDFILEATQDDYVLEVR---HFQCPKWPNPDSPISKTF-ELI 1538

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                             GPM+VH   GG  +G + A+   +   E+E+S DV+   K + 
Sbjct: 1539 SVIKEEAANRD------GPMIVHDEHGGVTAGTFCALTTLMHQLEKENSVDVYQVAKMIN 1592

Query: 225  ESRKGLIENEEQYKFVYDTL 244
              R G+  + EQY+F+Y  +
Sbjct: 1593 LMRPGVFADIEQYQFLYKVI 1612


>Y00062-1|CAA68269.1| 1143|Homo sapiens protein ( Human mRNA for T200
            leukocyte common antigen (CD45, LC-A). ).
          Length = 1143

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 555  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 614

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 615  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 668

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 669  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 726

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 727  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 786

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 787  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 843

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 844  DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 903

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 904  GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 950

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 951  SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1009

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 1010 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1049



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 860  IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 917

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 918  -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 972

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 973  -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1031

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1032 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1083

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1084 EFDNEVDKVKQ 1094



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 493 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 549

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 550 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 609

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 610 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 658

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 659 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 717

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 718 VYGYVVKLRRQRCLMVQ 734


>M23492-1|AAD15273.2| 1114|Homo sapiens T200 leukocyte common antigen
            precursor protein.
          Length = 1114

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 526  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 585

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 586  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 639

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 640  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 697

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 698  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 757

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 758  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 814

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 815  DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 874

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 875  GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 921

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 922  SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 980

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 981  SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1020



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 831  IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 888

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 889  -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 943

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 944  -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1002

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1003 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1054

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1055 EFDNEVDKVKQ 1065



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 464 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 520

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 521 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 580

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 581 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 629

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 630 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 688

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 689 VYGYVVKLRRQRCLMVQ 705


>AL355988-3|CAI19379.1| 1145|Homo sapiens protein tyrosine
            phosphatase, receptor type, C protein.
          Length = 1145

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 557  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 616

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 617  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 670

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 671  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 728

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 729  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 788

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 789  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 845

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 846  DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 905

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 906  GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 952

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 953  SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1011

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 1012 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1051



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 862  IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 919

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 920  -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 974

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 975  -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1033

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1034 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1085

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1086 EFDNEVDKVKQ 1096



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 495 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 551

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 552 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 611

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 612 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 660

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 661 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 719

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 720 VYGYVVKLRRQRCLMVQ 736


>AL355988-2|CAI19378.1| 1306|Homo sapiens protein tyrosine
            phosphatase, receptor type, C protein.
          Length = 1306

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 718  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 777

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 778  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 831

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 832  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 889

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 890  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 949

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 950  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 1006

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 1007 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1066

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 1067 GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 1113

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 1114 SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1172

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 1173 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1212



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 1023 IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 1080

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 1081 -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 1135

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 1136 -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1194

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1195 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1246

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1247 EFDNEVDKVKQ 1257



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 656 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 712

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 713 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 772

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 773 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 821

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 822 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 880

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 881 VYGYVVKLRRQRCLMVQ 897


>AL157402-4|CAI15640.1| 1145|Homo sapiens protein tyrosine
            phosphatase, receptor type, C protein.
          Length = 1145

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 557  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 616

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 617  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 670

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 671  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 728

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 729  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 788

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 789  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 845

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 846  DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 905

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 906  GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 952

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 953  SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1011

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 1012 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1051



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 862  IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 919

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 920  -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 974

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 975  -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1033

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1034 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1085

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1086 EFDNEVDKVKQ 1096



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 495 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 551

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 552 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 611

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 612 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 660

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 661 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 719

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 720 VYGYVVKLRRQRCLMVQ 736


>AL157402-3|CAI15641.1| 1306|Homo sapiens protein tyrosine
            phosphatase, receptor type, C protein.
          Length = 1306

 Score =  209 bits (511), Expect = 4e-53
 Identities = 149/520 (28%), Positives = 247/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 718  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 777

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 778  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 831

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 832  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 889

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 890  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 949

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 950  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 1006

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 1007 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1066

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 1067 GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 1113

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 1114 SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1172

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ RP +V
Sbjct: 1173 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMV 1212



 Score =  125 bits (302), Expect = 8e-28
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 1023 IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 1080

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 1081 -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 1135

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 1136 -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1194

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1195 VDIFQVVKALRKARPGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1246

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1247 EFDNEVDKVKQ 1257



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 656 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 712

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 713 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 772

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 773 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 821

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 822 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 880

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 881 VYGYVVKLRRQRCLMVQ 897


>Y00638-1|CAA68669.1| 1304|Homo sapiens protein ( Human mRNA for
            leukocyte common antigen (T200). ).
          Length = 1304

 Score =  205 bits (501), Expect = 6e-52
 Identities = 148/520 (28%), Positives = 246/520 (47%), Gaps = 55/520 (10%)

Query: 46   KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
            +P+ YI  QGP ++TV DFWRMIW+++A  IVM+T+  +  +  C +YWP  +E    +G
Sbjct: 716  EPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFG 775

Query: 106  DISVGIVQEEELANFFIRTFRLY-KTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFX 164
            D+ V I Q +   ++ I+   +  K EK      R +    +T W  H  P    LL   
Sbjct: 776  DVVVKINQHKRCPDYIIQKLNIVNKKEKAT---GREVTHIQFTSWPDHGVPEDPHLL--- 829

Query: 165  XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                         N  +GP+VVHC+ G GR+G Y+ IDA LE  E E+  DV+G + KLR
Sbjct: 830  --LKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLR 887

Query: 225  ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQ 284
              R  +++ E QY  ++  L E+   G +   +SEL   L    +RDP ++ +  + E+Q
Sbjct: 888  RQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQ 947

Query: 285  QICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYL---------TSFQGNSFTD 335
            ++       T      G++ +N+ KNR+  V+P D  R  L         +    +  +D
Sbjct: 948  RLPSYRSWRTQHI---GNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSD 1004

Query: 336  ----------YINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPK 385
                      YINA F+  Y KP   IA + PL  T G+FW +++  +   +V+L     
Sbjct: 1005 DDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKH 1064

Query: 386  NSQQY-PPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAP 444
              Q+    +W EG+ +  YG +     V         T+  R+        EL    +  
Sbjct: 1065 GDQEICAQYWGEGKQT--YGDI----EVDLKDTDKSSTYTLRV-------FELRHSKRKD 1111

Query: 445  TKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW--RQRTDYG-------PVCVVSPDG 495
            ++TV  +Q T W +  ++P+    L+ ++ +V++   ++ +  G       P+ +   DG
Sbjct: 1112 SRTVYQYQYTNWSV-EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDG 1170

Query: 496  RSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLV 535
              + G++CA    +E       VD+FQ VK +R+ R  +V
Sbjct: 1171 SQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARLGMV 1210



 Score =  125 bits (301), Expect = 1e-27
 Identities = 77/251 (30%), Positives = 124/251 (49%), Gaps = 23/251 (9%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            + S  KP+  I  QGP ++T+ DFW+MI+Q +   IVMLT+     + +C QYW   K  
Sbjct: 1021 IMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQYWGEGK-- 1078

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             +TYGDI V +   ++ + + +R F L  +++    + R + Q+ YT W     P     
Sbjct: 1079 -QTYGDIEVDLKDTDKSSTYTLRVFELRHSKRK---DSRTVYQYQYTNWSVEQLPAEPK- 1133

Query: 161  LEFXXXXXXXXXXXXXXNPAAG-------PMVVHCNDGGGRSGVYLAIDANLELAEEEDS 213
             E               N + G       P+++HC DG  ++G++ A+   LE AE E+ 
Sbjct: 1134 -ELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV 1192

Query: 214  FDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
             D+F  +K LR++R G++   EQY+F+YD +        S +P ++  Q  K   Q D +
Sbjct: 1193 VDIFQVVKALRKARLGMVSTFEQYQFLYDVI-------ASTYP-AQNGQVKKNNHQEDKI 1244

Query: 274  TKLNEYQKEYQ 284
               NE  K  Q
Sbjct: 1245 EFDNEVDKVKQ 1255



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 71/257 (27%), Positives = 123/257 (47%), Gaps = 17/257 (6%)

Query: 282 EYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVF 341
           E+Q I +   +F I +     +  N+ KNR V ++P D  R  L+   G++ ++YINA +
Sbjct: 654 EFQSIPRVFSKFPIKEA---RKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASY 710

Query: 342 VDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRH- 399
           +DG+ +PR+YIA + P   T  +FW ++++ +   +V++      N  +   +WP     
Sbjct: 711 IDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEG 770

Query: 400 SKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMG 459
           ++ +G V     V  N +     +I +    I++  E     KA  + V   Q T WP  
Sbjct: 771 TRAFGDVV----VKINQHKRCPDYIIQ-KLNIVNKKE-----KATGREVTHIQFTSWP-D 819

Query: 460 HKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVD 519
           H VP   + L++L   V  +      GP+ V    G  R G Y   +A +E +    +VD
Sbjct: 820 HGVPEDPHLLLKLRRRVNAFSNFFS-GPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVD 878

Query: 520 VFQAVKTVRRHRPQLVE 536
           V+  V  +RR R  +V+
Sbjct: 879 VYGYVVKLRRQRCLMVQ 895


>X54135-1|CAA38070.1|  613|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 613

 Score =  171 bits (415), Expect = 2e-41
 Identities = 104/312 (33%), Positives = 158/312 (50%), Gaps = 18/312 (5%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           +PKAYI  QGP + T  DFWRMIW+     IVM+T   +  +  C QYWP   +  E YG
Sbjct: 314 RPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPA--DGSEEYG 371

Query: 106 DISVGIVQEEELANFFIRTFRLYKTE--KGVVIEE---RFILQFHYTQWHSHTCP-FSNA 159
           +  V     + LA + +R F L  T+  KG        R + Q+HYTQW     P +S  
Sbjct: 372 NFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLP 431

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
           +L F                A GP+VVHC+ G GR+G Y+ +D+ L+  + E + ++FG 
Sbjct: 432 VLTFVRKAAYAKRH------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGF 485

Query: 220 LKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEY 279
           LK +R  R  L++ EEQY F++DTL E ++   +    S +   +       P  K  + 
Sbjct: 486 LKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGK-TKL 544

Query: 280 QKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINA 339
           +K++Q + +        D +   +  NREKNR   ++P +  R  ++S  G   TDYINA
Sbjct: 545 EKQFQLLSQS--NIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSGEG-TDYINA 601

Query: 340 VFVDGYTKPREY 351
            ++ GY +  E+
Sbjct: 602 SYIMGYYQSNEF 613



 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 79/287 (27%), Positives = 135/287 (47%), Gaps = 15/287 (5%)

Query: 256 PVSELSQRLKQKSQRDPVTKLNEYQKE-YQQICKQTPRFTIGDCAGGHRGDNREKNRDVL 314
           P+    + +         T+  E  KE YQ++   T    I   +  H  DN+ KNR + 
Sbjct: 221 PIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHP-DNKHKNRYIN 279

Query: 315 VVPPDNFRPYLTSF--QGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDY 372
           +V  D+ R  L     +    TDYINA +VDGY +P+ YIA + PL  T  +FW +++++
Sbjct: 280 IVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEH 339

Query: 373 ECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGP-VFTIDHVSHNHYTNIKTWIFRINKK 430
               +V++  +  K  ++   +WP    S++YG  + T   V    Y  ++ +  R N K
Sbjct: 340 NVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFLVTQKSVQVLAYYTVRNFTLR-NTK 397

Query: 431 IISLTELMAGVKAPTKTVQLFQLTCWP-MGHKVPSSTNSLVELMNMVERWRQRTDYGPVC 489
           I   ++   G +   + V  +  T WP MG  VP  +  ++  +     + +R   GPV 
Sbjct: 398 IKKGSQ--KG-RPSGRVVTQYHYTQWPDMG--VPEYSLPVLTFVRKA-AYAKRHAVGPVV 451

Query: 490 VVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           V    G  R G Y   ++ ++Q+   G V++F  +K +R  R  LV+
Sbjct: 452 VHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQ 498


>BC040543-1|AAH40543.1|  279|Homo sapiens PTPRM protein protein.
          Length = 279

 Score =  152 bits (368), Expect = 8e-36
 Identities = 94/276 (34%), Positives = 149/276 (53%), Gaps = 18/276 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           DP T  ++ ++E++ +   TP   + DC+      N EKNR + ++PPD   P+L +  G
Sbjct: 5   DPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDG 64

Query: 331 NSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CVPPKNSQQ 389
            S ++YINA  +D Y +P  +I T+ PL  T  +FW LV DY C +VV+L  V P  +Q 
Sbjct: 65  ES-SNYINAALMDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQL 121

Query: 390 YPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
            P +WPE G H  ++GP+  ++ VS +   +I + IFRI           A  +   + V
Sbjct: 122 CPQYWPENGVH--RHGPI-QVEFVSADLEEDIISRIFRIYN--------AARPQDGYRMV 170

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD--YGPVCVVSPDGRSRAGVYCAAN 506
           Q FQ   WPM    P S  S ++L+  V++W++  +   G   V   +G  R+G +CA +
Sbjct: 171 QQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAIS 230

Query: 507 ACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
              E +     VDVF AVKT+R ++P +V+ + + K
Sbjct: 231 IVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYK 266



 Score =  106 bits (254), Expect = 5e-22
 Identities = 66/212 (31%), Positives = 98/212 (46%), Gaps = 8/212 (3%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           + S  +P A+IVTQ P  +TV DFWR++      ++VML         +C QYWP N   
Sbjct: 75  MDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP--AQLCPQYWPENGV- 131

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHT-CPFSNA 159
              +G I V  V  +   +   R FR+Y   +      R + QF +  W  +   P S  
Sbjct: 132 -HRHGPIQVEFVSADLEEDIISRIFRIYNAARPQD-GYRMVQQFQFLGWPMYRDTPVSKR 189

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
              F              N   G  VVHC +GGGRSG + AI    E+   + + DVF  
Sbjct: 190 --SFLKLIRQVDKWQEEYNGGEGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHA 247

Query: 220 LKKLRESRKGLIENEEQYKFVYDTLEEHVVCG 251
           +K LR ++  +++  +QYKF Y+   E++  G
Sbjct: 248 VKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG 279


>BX648771-1|CAE46198.1| 1956|Homo sapiens hypothetical protein
            protein.
          Length = 1956

 Score =  134 bits (325), Expect = 1e-30
 Identities = 74/231 (32%), Positives = 124/231 (53%), Gaps = 12/231 (5%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            + YIVTQGP   T  DFW+M+W++    IVM+T+  +  +V C +YWP +++    YGD+
Sbjct: 1729 REYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDRYWPADQDS-LYYGDL 1787

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFXXX 166
             + ++ E  L  + IR F++   E+  +   R I  FHYT W  H  P  + +L++F   
Sbjct: 1788 ILQMLSESVLPEWTIREFKICGEEQ--LDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRT 1845

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                       +P AGP VVHC+ G GR+G ++A+D  L+  + +DS D++G +  LR  
Sbjct: 1846 VRDYINR----SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 1901

Query: 227  RKGLIENEEQYKFVY----DTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
            R  +++ E QY +++    D L    +      P+  + + +  +  RDPV
Sbjct: 1902 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPV 1952



 Score =  103 bits (246), Expect = 5e-21
 Identities = 71/239 (29%), Positives = 118/239 (49%), Gaps = 15/239 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++P D  R  L++   +  +DYINA ++ G    REYI T+ PL  T+ +
Sbjct: 1685 ENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDD 1744

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++     +V++  CV  K   +   +WP  + S  YG +  +  +S    + +  
Sbjct: 1745 FWKMVWEQNVHNIVMVTQCV-EKGRVKCDRYWPADQDSLYYGDLI-LQMLSE---SVLPE 1799

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   KI    +L A      + ++ F  T WP  H VP +T SL++ +  V  +  R
Sbjct: 1800 WTIR-EFKICGEEQLDA-----HRLIRHFHYTVWP-DHGVPETTQSLIQFVRTVRDYINR 1852

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCE 540
            +   GP  V    G  R G + A +  ++Q+     VD++ AV  +R HR  +V+  C+
Sbjct: 1853 SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ 1911


>AJ430580-1|CAD23182.1|  536|Homo sapiens tyrosine phosphatase
           epsilon PD1 protein.
          Length = 536

 Score =  134 bits (325), Expect = 1e-30
 Identities = 80/241 (33%), Positives = 121/241 (50%), Gaps = 12/241 (4%)

Query: 28  LPGFSCLIAFTISLKSLLKPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFI 86
           L G  C      S     K K  +I  QGP ++TV DFWRM+W++++A IVMLT   +  
Sbjct: 123 LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK 182

Query: 87  KVMCVQYWPPNKEKDETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHY 146
           +  C QYWP   +   TYG+I V +     L ++ IR F +           R + Q H+
Sbjct: 183 EEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHF 240

Query: 147 TQWHSHTCPFSN-ALLEFXXXXXXXXXXXXXXNPA-AGPMVVHCNDGGGRSGVYLAIDAN 204
           T W     PF+   +L+F              NP  AGP+VVHC+ G GR+G ++ IDA 
Sbjct: 241 TSWPDFGVPFTPIGMLKFLKKVKTL-------NPVHAGPIVVHCSAGVGRTGTFIVIDAM 293

Query: 205 LELAEEEDSFDVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRL 264
           + +   E   DVF  + ++R  R  +++ + QY F+Y  L E+ + G +   VS L + L
Sbjct: 294 MAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHL 353

Query: 265 K 265
           +
Sbjct: 354 Q 354



 Score =  100 bits (240), Expect = 3e-20
 Identities = 79/310 (25%), Positives = 143/310 (46%), Gaps = 21/310 (6%)

Query: 229 GLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVTKLNEYQKEYQQICK 288
           G++E +EQ + +  +            PV  L + ++ +S  D      ++++E+  +  
Sbjct: 31  GILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADD----CKQFREEFNSL-- 84

Query: 289 QTPRFTI-GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTK 347
             P   I G     ++ +NREKNR   ++P D+ R  L+   G   +DYINA ++DGY +
Sbjct: 85  --PSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE 142

Query: 348 PREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV 406
             ++IA + P   T  +FW +V++ + A +V+L  +  +  ++   +WP+ +    YG +
Sbjct: 143 KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD-QGCWTYGNI 201

Query: 407 FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST 466
                V       +  +  R   K     +L  G KAP    QL   T WP    VP + 
Sbjct: 202 ----RVCVEDCVVLVDYTIR---KFCIQPQLPDGCKAPRLVSQL-HFTSWP-DFGVPFTP 252

Query: 467 NSLVELMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKT 526
             +++ +  V+        GP+ V    G  R G +   +A +  +    +VDVF+ V  
Sbjct: 253 IGMLKFLKKVKTLNP-VHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSR 311

Query: 527 VRRHRPQLVE 536
           +R  RPQ+V+
Sbjct: 312 IRNQRPQMVQ 321


>X54131-1|CAA38066.1| 1997|Homo sapiens protein-tyrosine phosphatase
            protein.
          Length = 1997

 Score =  134 bits (324), Expect = 2e-30
 Identities = 74/231 (32%), Positives = 123/231 (53%), Gaps = 12/231 (5%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            + YIVTQGP   T  DFW+M+W++    IVM+T+  +  +V C  YWP +++    YGD+
Sbjct: 1770 REYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS-LYYGDL 1828

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFXXX 166
             + ++ E  L  + IR F++   E+  +   R I  FHYT W  H  P  + +L++F   
Sbjct: 1829 ILQMLSESVLPEWTIREFKICGEEQ--LDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRT 1886

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                       +P AGP VVHC+ G GR+G ++A+D  L+  + +DS D++G +  LR  
Sbjct: 1887 VRDYINR----SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 1942

Query: 227  RKGLIENEEQYKFVY----DTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
            R  +++ E QY +++    D L    +      P+  + + +  +  RDPV
Sbjct: 1943 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPV 1993



 Score =  103 bits (246), Expect = 5e-21
 Identities = 71/239 (29%), Positives = 118/239 (49%), Gaps = 15/239 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++P D  R  L++   +  +DYINA ++ G    REYI T+ PL  T+ +
Sbjct: 1726 ENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDD 1785

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++     +V++  CV  K   +   +WP  + S  YG +  +  +S    + +  
Sbjct: 1786 FWKMVWEQNVHNIVMVTQCV-EKGRVKCDHYWPADQDSLYYGDLI-LQMLSE---SVLPE 1840

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   KI    +L A      + ++ F  T WP  H VP +T SL++ +  V  +  R
Sbjct: 1841 WTIR-EFKICGEEQLDA-----HRLIRHFHYTVWP-DHGVPETTQSLIQFVRTVRDYINR 1893

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCE 540
            +   GP  V    G  R G + A +  ++Q+     VD++ AV  +R HR  +V+  C+
Sbjct: 1894 SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ 1952


>BC113463-1|AAI13464.1| 1997|Homo sapiens protein tyrosine
            phosphatase, receptor type, B protein.
          Length = 1997

 Score =  134 bits (324), Expect = 2e-30
 Identities = 74/231 (32%), Positives = 123/231 (53%), Gaps = 12/231 (5%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            + YIVTQGP   T  DFW+M+W++    IVM+T+  +  +V C  YWP +++    YGD+
Sbjct: 1770 REYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS-LYYGDL 1828

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFXXX 166
             + ++ E  L  + IR F++   E+  +   R I  FHYT W  H  P  + +L++F   
Sbjct: 1829 ILQMLSESVLPEWTIREFKICGEEQ--LDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRT 1886

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                       +P AGP VVHC+ G GR+G ++A+D  L+  + +DS D++G +  LR  
Sbjct: 1887 VRDYINR----SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 1942

Query: 227  RKGLIENEEQYKFVY----DTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
            R  +++ E QY +++    D L    +      P+  + + +  +  RDPV
Sbjct: 1943 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPV 1993



 Score =  103 bits (246), Expect = 5e-21
 Identities = 71/239 (29%), Positives = 118/239 (49%), Gaps = 15/239 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++P D  R  L++   +  +DYINA ++ G    REYI T+ PL  T+ +
Sbjct: 1726 ENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDD 1785

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++     +V++  CV  K   +   +WP  + S  YG +  +  +S    + +  
Sbjct: 1786 FWKMVWEQNVHNIVMVTQCV-EKGRVKCDHYWPADQDSLYYGDLI-LQMLSE---SVLPE 1840

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   KI    +L A      + ++ F  T WP  H VP +T SL++ +  V  +  R
Sbjct: 1841 WTIR-EFKICGEEQLDA-----HRLIRHFHYTVWP-DHGVPETTQSLIQFVRTVRDYINR 1893

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCE 540
            +   GP  V    G  R G + A +  ++Q+     VD++ AV  +R HR  +V+  C+
Sbjct: 1894 SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ 1952


>BC101679-1|AAI01680.1| 1997|Homo sapiens protein tyrosine
            phosphatase, receptor type, B protein.
          Length = 1997

 Score =  134 bits (324), Expect = 2e-30
 Identities = 74/231 (32%), Positives = 123/231 (53%), Gaps = 12/231 (5%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            + YIVTQGP   T  DFW+M+W++    IVM+T+  +  +V C  YWP +++    YGD+
Sbjct: 1770 REYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDS-LYYGDL 1828

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCP-FSNALLEFXXX 166
             + ++ E  L  + IR F++   E+  +   R I  FHYT W  H  P  + +L++F   
Sbjct: 1829 ILQMLSESVLPEWTIREFKICGEEQ--LDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRT 1886

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                       +P AGP VVHC+ G GR+G ++A+D  L+  + +DS D++G +  LR  
Sbjct: 1887 VRDYINR----SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 1942

Query: 227  RKGLIENEEQYKFVY----DTLEEHVVCGISWFPVSELSQRLKQKSQRDPV 273
            R  +++ E QY +++    D L    +      P+  + + +  +  RDPV
Sbjct: 1943 RVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHRDPV 1993



 Score =  103 bits (246), Expect = 5e-21
 Identities = 71/239 (29%), Positives = 118/239 (49%), Gaps = 15/239 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   ++P D  R  L++   +  +DYINA ++ G    REYI T+ PL  T+ +
Sbjct: 1726 ENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDD 1785

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++     +V++  CV  K   +   +WP  + S  YG +  +  +S    + +  
Sbjct: 1786 FWKMVWEQNVHNIVMVTQCV-EKGRVKCDHYWPADQDSLYYGDLI-LQMLSE---SVLPE 1840

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   KI    +L A      + ++ F  T WP  H VP +T SL++ +  V  +  R
Sbjct: 1841 WTIR-EFKICGEEQLDA-----HRLIRHFHYTVWP-DHGVPETTQSLIQFVRTVRDYINR 1893

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCE 540
            +   GP  V    G  R G + A +  ++Q+     VD++ AV  +R HR  +V+  C+
Sbjct: 1894 SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQ 1952


>U10886-1|AAB36687.1| 1337|Homo sapiens density enhanced phosphatase-1
            protein.
          Length = 1337

 Score =  132 bits (320), Expect = 5e-30
 Identities = 68/193 (35%), Positives = 105/193 (54%), Gaps = 8/193 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            K +I TQGP  +T+ DFWRM+W++   AI+MLTK  +  +  C +YWP  + +D  YGDI
Sbjct: 1107 KDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQD--YGDI 1164

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            +V +  E  L  + IR F +   +     E   + QFH+T W  H  P +  LL      
Sbjct: 1165 TVAMTSEIVLPEWTIRDFTVKNIQTS---ESHPLRQFHFTSWPDHGVPDTTDLL---INF 1218

Query: 168  XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                      +P   P++VHC+ G GR+G ++AID  +   E E++ DV+G +  LR  R
Sbjct: 1219 RYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHR 1278

Query: 228  KGLIENEEQYKFV 240
              +++ E+QY F+
Sbjct: 1279 PLMVQTEDQYVFL 1291



 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 72/236 (30%), Positives = 115/236 (48%), Gaps = 20/236 (8%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   V+P D  R  L S Q +S  DYINA ++ GY   +++IAT+ PL  T  +
Sbjct: 1064 ENRGKNRYNNVLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKD 1122

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++    A+++L  CV  +   +   +WP  + ++ YG + T+   S      +  
Sbjct: 1123 FWRMVWEKNVYAIIMLTKCV-EQGRTKCEEYWP-SKQAQDYGDI-TVAMTSE---IVLPE 1176

Query: 423  WIFR-INKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW-R 480
            W  R    K I  +E        +  ++ F  T WP  H VP +T+ L+    +V  + +
Sbjct: 1177 WTIRDFTVKNIQTSE--------SHPLRQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMK 1227

Query: 481  QRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            Q     P+ V    G  R G + A +  I Q+     VDV+  V  +R HRP +V+
Sbjct: 1228 QSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQ 1283


>D37781-1|BAA07035.1| 1337|Homo sapiens protein-tyrosine phosphatase
            protein.
          Length = 1337

 Score =  132 bits (320), Expect = 5e-30
 Identities = 68/193 (35%), Positives = 105/193 (54%), Gaps = 8/193 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            K +I TQGP  +T+ DFWRM+W++   AI+MLTK  +  +  C +YWP  + +D  YGDI
Sbjct: 1107 KDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQD--YGDI 1164

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            +V +  E  L  + IR F +   +     E   + QFH+T W  H  P +  LL      
Sbjct: 1165 TVAMTSEIVLPEWTIRDFTVKNIQTS---ESHPLRQFHFTSWPDHGVPDTTDLL---INF 1218

Query: 168  XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                      +P   P++VHC+ G GR+G ++AID  +   E E++ DV+G +  LR  R
Sbjct: 1219 RYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHR 1278

Query: 228  KGLIENEEQYKFV 240
              +++ E+QY F+
Sbjct: 1279 PLMVQTEDQYVFL 1291



 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 72/236 (30%), Positives = 115/236 (48%), Gaps = 20/236 (8%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   V+P D  R  L S Q +S  DYINA ++ GY   +++IAT+ PL  T  +
Sbjct: 1064 ENRGKNRYNNVLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKD 1122

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++    A+++L  CV  +   +   +WP  + ++ YG + T+   S      +  
Sbjct: 1123 FWRMVWEKNVYAIIMLTKCV-EQGRTKCEEYWP-SKQAQDYGDI-TVAMTSE---IVLPE 1176

Query: 423  WIFR-INKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW-R 480
            W  R    K I  +E        +  ++ F  T WP  H VP +T+ L+    +V  + +
Sbjct: 1177 WTIRDFTVKNIQTSE--------SHPLRQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMK 1227

Query: 481  QRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            Q     P+ V    G  R G + A +  I Q+     VDV+  V  +R HRP +V+
Sbjct: 1228 QSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQ 1283


>AF387844-1|AAM69432.1| 1305|Homo sapiens protein tyrosine phosphatase
            receptor type J protein.
          Length = 1305

 Score =  132 bits (320), Expect = 5e-30
 Identities = 68/193 (35%), Positives = 105/193 (54%), Gaps = 8/193 (4%)

Query: 48   KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
            K +I TQGP  +T+ DFWRM+W++   AI+MLTK  +  +  C +YWP  + +D  YGDI
Sbjct: 1075 KDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPSKQAQD--YGDI 1132

Query: 108  SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXX 167
            +V +  E  L  + IR F +   +     E   + QFH+T W  H  P +  LL      
Sbjct: 1133 TVAMTSEIVLPEWTIRDFTVKNIQTS---ESHPLRQFHFTSWPDHGVPDTTDLL---INF 1186

Query: 168  XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                      +P   P++VHC+ G GR+G ++AID  +   E E++ DV+G +  LR  R
Sbjct: 1187 RYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHR 1246

Query: 228  KGLIENEEQYKFV 240
              +++ E+QY F+
Sbjct: 1247 PLMVQTEDQYVFL 1259



 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 72/236 (30%), Positives = 115/236 (48%), Gaps = 20/236 (8%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +NR KNR   V+P D  R  L S Q +S  DYINA ++ GY   +++IAT+ PL  T  +
Sbjct: 1032 ENRGKNRYNNVLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKD 1090

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW +V++    A+++L  CV  +   +   +WP  + ++ YG + T+   S      +  
Sbjct: 1091 FWRMVWEKNVYAIIMLTKCV-EQGRTKCEEYWP-SKQAQDYGDI-TVAMTSE---IVLPE 1144

Query: 423  WIFR-INKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERW-R 480
            W  R    K I  +E        +  ++ F  T WP  H VP +T+ L+    +V  + +
Sbjct: 1145 WTIRDFTVKNIQTSE--------SHPLRQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMK 1195

Query: 481  QRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            Q     P+ V    G  R G + A +  I Q+     VDV+  V  +R HRP +V+
Sbjct: 1196 QSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYGIVYDLRMHRPLMVQ 1251


>Z48541-1|CAA88425.1| 1216|Homo sapiens protein tyrosine phosphatase
            protein.
          Length = 1216

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47   PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
            P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 1004 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 1062

Query: 107  ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
            I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 1063 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 1114

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                         + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 1115 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 1174

Query: 227  RKGLIENEEQYKFVYDTLE 245
            R  +++ EEQY F++  ++
Sbjct: 1175 RMSMVQTEEQYIFIHQCVQ 1193



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 962  NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 1021

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 1022 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 1080

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
            FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 1081 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 1127

Query: 483  TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 1128 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 1180


>U20489-1|AAA82892.1| 1188|Homo sapiens glomerular epithelial protein
            1 protein.
          Length = 1188

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47   PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
            P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 976  PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 1034

Query: 107  ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
            I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 1035 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 1086

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                         + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 1087 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 1146

Query: 227  RKGLIENEEQYKFVYDTLE 245
            R  +++ EEQY F++  ++
Sbjct: 1147 RMSMVQTEEQYIFIHQCVQ 1165



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 934  NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 993

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 994  WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 1052

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
            FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 1053 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 1099

Query: 483  TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 1100 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 1152


>BC126203-1|AAI26204.1| 1216|Homo sapiens protein tyrosine
            phosphatase, receptor type, O protein.
          Length = 1216

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47   PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
            P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 1004 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 1062

Query: 107  ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
            I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 1063 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 1114

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                         + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 1115 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 1174

Query: 227  RKGLIENEEQYKFVYDTLE 245
            R  +++ EEQY F++  ++
Sbjct: 1175 RMSMVQTEEQYIFIHQCVQ 1193



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 962  NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 1021

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 1022 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 1080

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
            FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 1081 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 1127

Query: 483  TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 1128 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 1180


>BC126201-1|AAI26202.1| 1216|Homo sapiens protein tyrosine
            phosphatase, receptor type, O protein.
          Length = 1216

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47   PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
            P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 1004 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 1062

Query: 107  ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
            I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 1063 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 1114

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                         + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 1115 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 1174

Query: 227  RKGLIENEEQYKFVYDTLE 245
            R  +++ EEQY F++  ++
Sbjct: 1175 RMSMVQTEEQYIFIHQCVQ 1193



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306  NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
            NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 962  NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 1021

Query: 366  WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 1022 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 1080

Query: 425  FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
            FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 1081 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 1127

Query: 483  TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 1128 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 1180


>AF187044-1|AAF04087.1|  377|Homo sapiens protein tyrosine
           phosphatase receptor-type O truncated PTPROt protein.
          Length = 377

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47  PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
           P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 165 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 223

Query: 107 ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
           I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 224 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 275

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                        + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 276 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 335

Query: 227 RKGLIENEEQYKFVYDTLE 245
           R  +++ EEQY F++  ++
Sbjct: 336 RMSMVQTEEQYIFIHQCVQ 354



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306 NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
           NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 123 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 182

Query: 366 WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
           W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 183 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 241

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
           FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 242 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 288

Query: 483 TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 289 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 341


>AF187043-1|AAF04086.1|  405|Homo sapiens protein tyrosine
           phosphatase receptor-type O truncated PTPROt protein.
          Length = 405

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47  PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
           P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 193 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 251

Query: 107 ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
           I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 252 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 303

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                        + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 304 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363

Query: 227 RKGLIENEEQYKFVYDTLE 245
           R  +++ EEQY F++  ++
Sbjct: 364 RMSMVQTEEQYIFIHQCVQ 382



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306 NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
           NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 151 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 210

Query: 366 WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
           W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 211 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 269

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
           FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 270 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 316

Query: 483 TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 317 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 369


>AF187042-1|AAF04085.1|  377|Homo sapiens protein tyrosine
           phosphatase receptor-type O truncated PTPROt protein.
          Length = 377

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47  PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
           P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 165 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 223

Query: 107 ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
           I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 224 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 275

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                        + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 276 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 335

Query: 227 RKGLIENEEQYKFVYDTLE 245
           R  +++ EEQY F++  ++
Sbjct: 336 RMSMVQTEEQYIFIHQCVQ 354



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306 NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
           NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 123 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 182

Query: 366 WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
           W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 183 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 241

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
           FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 242 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 288

Query: 483 TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 289 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 341


>AF152378-1|AAD55680.1|  405|Homo sapiens protein tyrosine
           phosphatase receptor-type O truncated PTPROT protein.
          Length = 405

 Score =  132 bits (318), Expect = 9e-30
 Identities = 65/199 (32%), Positives = 110/199 (55%), Gaps = 9/199 (4%)

Query: 47  PKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD 106
           P+ YI TQGP  +T  DFW+M+ Q+++  IVMLT+  +  +V C  YWP  +E    YGD
Sbjct: 193 PQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPI-AYGD 251

Query: 107 ISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXX 166
           I+V ++ EEE  ++  R FR+   +     E + ++ F+YT W  H  P +NA       
Sbjct: 252 ITVEMISEEEQDDWACRHFRINYAD-----EMQDVMHFNYTAWPDHGVPTANAA---ESI 303

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRES 226
                        + GPM++HC+ G GR+G ++A+D  L+   + +  D+ G + ++R  
Sbjct: 304 LQFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSY 363

Query: 227 RKGLIENEEQYKFVYDTLE 245
           R  +++ EEQY F++  ++
Sbjct: 364 RMSMVQTEEQYIFIHQCVQ 382



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 67/234 (28%), Positives = 110/234 (47%), Gaps = 18/234 (7%)

Query: 306 NREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEF 365
           NR KNR   ++P D  R  L S       DYINA ++ GY  P+EYIAT+ PL  T+ +F
Sbjct: 151 NRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDF 210

Query: 366 WSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
           W +V   +   +V+L     K   +   +WP       YG + T++ +S     +     
Sbjct: 211 WKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDI-TVEMISEEEQDDWACRH 269

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSST--NSLVELMNMVERWRQR 482
           FRIN       E+        + V  F  T WP  H VP++    S+++ ++MV +   +
Sbjct: 270 FRINYA----DEM--------QDVMHFNYTAWP-DHGVPTANAAESILQFVHMVRQQATK 316

Query: 483 TDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           +  GP+ +    G  R G + A +  ++ +  H  VD+   V  +R +R  +V+
Sbjct: 317 SK-GPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQ 369


>BC111715-1|AAI11716.1|  937|Homo sapiens PTPRH protein protein.
          Length = 937

 Score =  128 bits (310), Expect = 8e-29
 Identities = 68/205 (33%), Positives = 107/205 (52%), Gaps = 9/205 (4%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +  L  P+ +I TQGP   TV DFWR++W++++  +VMLT   +  +V C  YWP + + 
Sbjct: 702 MPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQP 761

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
             T+G + V +V EE + N+ +R   L + E+   +  R   QFHY  W  H  P S + 
Sbjct: 762 C-THGHLRVTLVDEEVMENWTVRELLLLQVEEQKTLSVR---QFHYQAWPDHGVPSSPDT 817

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
           LL F                  GP +VHC+ G GR+G  +A+D  L   + E     F  
Sbjct: 818 LLAFWRMLRQWLDQTM----EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSF 873

Query: 220 LKKLRESRKGLIENEEQYKFVYDTL 244
           ++K+RESR  +++ E QY F++  +
Sbjct: 874 VRKMRESRPLMVQTEAQYVFLHQCI 898



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 68/235 (28%), Positives = 111/235 (47%), Gaps = 16/235 (6%)

Query: 305 DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
           +N  KNR   V+P D  R  L        +DYINA F+ G   P+E+IAT+ PL  T G+
Sbjct: 665 ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 724

Query: 365 FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
           FW LV++ +   +V+L  C+      +   +WP       +G +     V+      ++ 
Sbjct: 725 FWRLVWEQQSHTLVMLTNCM-EAGRVKCEHYWPLDSQPCTHGHL----RVTLVDEEVMEN 779

Query: 423 WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
           W  R   +++    L+   +  T +V+ F    WP  H VPSS ++L+    M+ +W  +
Sbjct: 780 WTVR---ELL----LLQVEEQKTLSVRQFHYQAWP-DHGVPSSPDTLLAFWRMLRQWLDQ 831

Query: 483 T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
           T + GP  V    G  R G   A +  + Q+   G +  F  V+ +R  RP +V+
Sbjct: 832 TMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQ 886


>D15049-1|BAA03645.2| 1117|Homo sapiens protein tyrosine phosphatase
            precursor protein.
          Length = 1117

 Score =  128 bits (308), Expect = 1e-28
 Identities = 68/205 (33%), Positives = 107/205 (52%), Gaps = 9/205 (4%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            +  L  P+ +I TQGP   TV DFWR++W++++  +VMLT   +  +V C  YWP + + 
Sbjct: 882  MPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQP 941

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              T+G + V +V EE + N+ +R   L + E+   +  R   QFHY  W  H  P S + 
Sbjct: 942  C-THGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVR---QFHYQAWPDHGVPSSPDT 997

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
            LL F                  GP +VHC+ G GR+G  +A+D  L   + E     F  
Sbjct: 998  LLAFWRMLRQWLDQTM----EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSF 1053

Query: 220  LKKLRESRKGLIENEEQYKFVYDTL 244
            ++K+RESR  +++ E QY F++  +
Sbjct: 1054 VRKMRESRPLMVQTEAQYVFLHQCI 1078



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 69/235 (29%), Positives = 110/235 (46%), Gaps = 16/235 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +N  KNR   V+P D  R  L        +DYINA F+ G   P+E+IAT+ PL  T G+
Sbjct: 845  ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 904

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW LV++ +   +V+L  C+      +   +WP       +G +  +  V      N   
Sbjct: 905  FWRLVWEQQSHTLVMLTNCM-EAGRVKCEHYWPLDSQPCTHGHL-RVTLVGEEVMEN--- 959

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   +++    L+   +  T +V+ F    WP  H VPSS ++L+    M+ +W  +
Sbjct: 960  WTVR---ELL----LLQVEEQKTLSVRQFHYQAWP-DHGVPSSPDTLLAFWRMLRQWLDQ 1011

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            T + GP  V    G  R G   A +  + Q+   G +  F  V+ +R  RP +V+
Sbjct: 1012 TMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQ 1066


>BC111716-1|AAI11717.1| 1115|Homo sapiens protein tyrosine
            phosphatase, receptor type, H, precursor protein.
          Length = 1115

 Score =  128 bits (308), Expect = 1e-28
 Identities = 68/205 (33%), Positives = 107/205 (52%), Gaps = 9/205 (4%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            +  L  P+ +I TQGP   TV DFWR++W++++  +VMLT   +  +V C  YWP + + 
Sbjct: 880  MPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQP 939

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              T+G + V +V EE + N+ +R   L + E+   +  R   QFHY  W  H  P S + 
Sbjct: 940  C-THGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVR---QFHYQAWPDHGVPSSPDT 995

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
            LL F                  GP +VHC+ G GR+G  +A+D  L   + E     F  
Sbjct: 996  LLAFWRMLRQWLDQTM----EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSF 1051

Query: 220  LKKLRESRKGLIENEEQYKFVYDTL 244
            ++K+RESR  +++ E QY F++  +
Sbjct: 1052 VRKMRESRPLMVQTEAQYVFLHQCI 1076



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 69/235 (29%), Positives = 110/235 (46%), Gaps = 16/235 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +N  KNR   V+P D  R  L        +DYINA F+ G   P+E+IAT+ PL  T G+
Sbjct: 843  ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 902

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW LV++ +   +V+L  C+      +   +WP       +G +  +  V      N   
Sbjct: 903  FWRLVWEQQSHTLVMLTNCM-EAGRVKCEHYWPLDSQPCTHGHL-RVTLVGEEVMEN--- 957

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   +++    L+   +  T +V+ F    WP  H VPSS ++L+    M+ +W  +
Sbjct: 958  WTVR---ELL----LLQVEEQKTLSVRQFHYQAWP-DHGVPSSPDTLLAFWRMLRQWLDQ 1009

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            T + GP  V    G  R G   A +  + Q+   G +  F  V+ +R  RP +V+
Sbjct: 1010 TMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQ 1064


>AF275150-1|AAF91411.1| 1115|Homo sapiens transmembrane-type protein
            tyrosine phosphatase H protein.
          Length = 1115

 Score =  128 bits (308), Expect = 1e-28
 Identities = 68/205 (33%), Positives = 107/205 (52%), Gaps = 9/205 (4%)

Query: 41   LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
            +  L  P+ +I TQGP   TV DFWR++W++++  +VMLT   +  +V C  YWP + + 
Sbjct: 880  MPGLWSPQEFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQP 939

Query: 101  DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              T+G + V +V EE + N+ +R   L + E+   +  R   QFHY  W  H  P S + 
Sbjct: 940  C-THGHLRVTLVGEEVMENWTVRELLLLQVEEQKTLSVR---QFHYQAWPDHGVPSSPDT 995

Query: 160  LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGC 219
            LL F                  GP +VHC+ G GR+G  +A+D  L   + E     F  
Sbjct: 996  LLAFWRMLRQWLDQTM----EGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSF 1051

Query: 220  LKKLRESRKGLIENEEQYKFVYDTL 244
            ++K+RESR  +++ E QY F++  +
Sbjct: 1052 VRKMRESRPLMVQTEAQYVFLHQCI 1076



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 69/235 (29%), Positives = 110/235 (46%), Gaps = 16/235 (6%)

Query: 305  DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
            +N  KNR   V+P D  R  L        +DYINA F+ G   P+E+IAT+ PL  T G+
Sbjct: 843  ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 902

Query: 365  FWSLVYDYECAAVVVL--CVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKT 422
            FW LV++ +   +V+L  C+      +   +WP       +G +  +  V      N   
Sbjct: 903  FWRLVWEQQSHTLVMLTNCM-EAGRVKCEHYWPLDSQPCTHGHL-RVTLVGEEVMEN--- 957

Query: 423  WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR 482
            W  R   +++    L+   +  T +V+ F    WP  H VPSS ++L+    M+ +W  +
Sbjct: 958  WTVR---ELL----LLQVEEQKTLSVRQFHYQAWP-DHGVPSSPDTLLAFWRMLRQWLDQ 1009

Query: 483  T-DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            T + GP  V    G  R G   A +  + Q+   G +  F  V+ +R  RP +V+
Sbjct: 1010 TMEGGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQ 1064


>X70766-1|CAA50045.1|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score =  126 bits (304), Expect = 5e-28
 Identities = 71/208 (34%), Positives = 112/208 (53%), Gaps = 12/208 (5%)

Query: 46  KPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETY 104
           KPK +YI TQG  ++TV DFWRM++QE +  IVM TK  +  K  CV+YWP      E Y
Sbjct: 322 KPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKE-Y 380

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEF 163
           G + V  V+E    ++ +R  +L K  +G    ER + Q+H+  W  H  P     +L+F
Sbjct: 381 GVMRVRNVKESAAHDYTLRELKLSKVGQGNT--ERTVWQYHFRTWPDHGVPSDPGGVLDF 438

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEED---SFDVFGCL 220
                            AGP+VVHC+ G GR+G ++ ID  +++  E+      DV   +
Sbjct: 439 LEEVHHKQESIMD----AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 494

Query: 221 KKLRESRKGLIENEEQYKFVYDTLEEHV 248
           + +R  R G+++ E QY+F+Y  ++ ++
Sbjct: 495 QMVRSQRSGMVQTEAQYRFIYMAVQHYI 522



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 71/302 (23%), Positives = 137/302 (45%), Gaps = 30/302 (9%)

Query: 258 SELSQRLKQKSQRDPVT-KLNE-YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
           +E+  R+++ S+    T K+ + + +E++ + +Q  +        G R +N+ KNR   +
Sbjct: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSR-KEGQRQENKNKNRYKNI 282

Query: 316 VPPDNFRPYLTSFQGNS-FTDYINAVFVD-------GYTKPRE-YIATEWPLMMTQGEFW 366
           +P D+ R  L     N   +DYINA  +          +KP++ YIAT+  L  T  +FW
Sbjct: 283 LPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFW 342

Query: 367 SLVYDYECAAVVVLCVP--PKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            +V+  E + V+V+      +   +   +WP+    K+YG V  + +V  +   +     
Sbjct: 343 RMVFQ-ENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYG-VMRVRNVKESAAHDYTLRE 400

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR-T 483
            +++K          G     +TV  +    WP  H VPS    +++ +  V   ++   
Sbjct: 401 LKLSK---------VGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIM 450

Query: 484 DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCE 540
           D GPV V    G  R G +   +  I+ + + G   ++DV + ++ VR  R  +V+   +
Sbjct: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510

Query: 541 LK 542
            +
Sbjct: 511 YR 512


>L07527-1|AAA17022.1|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score =  126 bits (304), Expect = 5e-28
 Identities = 71/208 (34%), Positives = 112/208 (53%), Gaps = 12/208 (5%)

Query: 46  KPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETY 104
           KPK +YI TQG  ++TV DFWRM++QE +  IVM TK  +  K  CV+YWP      E Y
Sbjct: 322 KPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKE-Y 380

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEF 163
           G + V  V+E    ++ +R  +L K  +G    ER + Q+H+  W  H  P     +L+F
Sbjct: 381 GVMRVRNVKESAAHDYTLRELKLSKVGQGNT--ERTVWQYHFRTWPDHGVPSDPGGVLDF 438

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEED---SFDVFGCL 220
                            AGP+VVHC+ G GR+G ++ ID  +++  E+      DV   +
Sbjct: 439 LEEVHHKQESIMD----AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 494

Query: 221 KKLRESRKGLIENEEQYKFVYDTLEEHV 248
           + +R  R G+++ E QY+F+Y  ++ ++
Sbjct: 495 QMVRSQRSGMVQTEAQYRFIYMAVQHYI 522



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 71/302 (23%), Positives = 137/302 (45%), Gaps = 30/302 (9%)

Query: 258 SELSQRLKQKSQRDPVT-KLNE-YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
           +E+  R+++ S+    T K+ + + +E++ + +Q  +        G R +N+ KNR   +
Sbjct: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSR-KEGQRQENKNKNRYKNI 282

Query: 316 VPPDNFRPYLTSFQGNS-FTDYINAVFVD-------GYTKPRE-YIATEWPLMMTQGEFW 366
           +P D+ R  L     N   +DYINA  +          +KP++ YIAT+  L  T  +FW
Sbjct: 283 LPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFW 342

Query: 367 SLVYDYECAAVVVLCVP--PKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            +V+  E + V+V+      +   +   +WP+    K+YG V  + +V  +   +     
Sbjct: 343 RMVFQ-ENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYG-VMRVRNVKESAAHDYTLRE 400

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR-T 483
            +++K          G     +TV  +    WP  H VPS    +++ +  V   ++   
Sbjct: 401 LKLSK---------VGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIM 450

Query: 484 DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCE 540
           D GPV V    G  R G +   +  I+ + + G   ++DV + ++ VR  R  +V+   +
Sbjct: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510

Query: 541 LK 542
            +
Sbjct: 511 YR 512


>L03535-1|AAA36611.1|  593|Homo sapiens phosphotyrosyl-protein
           phosphatase protein.
          Length = 593

 Score =  126 bits (304), Expect = 5e-28
 Identities = 71/208 (34%), Positives = 112/208 (53%), Gaps = 12/208 (5%)

Query: 46  KPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETY 104
           KPK +YI TQG  ++TV DFWRM++QE +  IVM TK  +  K  CV+YWP      E Y
Sbjct: 322 KPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKE-Y 380

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEF 163
           G + V  V+E    ++ +R  +L K  +G    ER + Q+H+  W  H  P     +L+F
Sbjct: 381 GVMRVRNVKESAAHDYTLRELKLSKVGQGNT--ERTVWQYHFRTWPDHGVPSDPGGVLDF 438

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEED---SFDVFGCL 220
                            AGP+VVHC+ G GR+G ++ ID  +++  E+      DV   +
Sbjct: 439 LEEVHHKQESIMD----AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 494

Query: 221 KKLRESRKGLIENEEQYKFVYDTLEEHV 248
           + +R  R G+++ E QY+F+Y  ++ ++
Sbjct: 495 QMVRSQRSGMVQTEAQYRFIYMAVQHYI 522



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 71/302 (23%), Positives = 137/302 (45%), Gaps = 30/302 (9%)

Query: 258 SELSQRLKQKSQRDPVT-KLNE-YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
           +E+  R+++ S+    T K+ + + +E++ + +Q  +        G R +N+ KNR   +
Sbjct: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSR-KEGQRQENKNKNRYKNI 282

Query: 316 VPPDNFRPYLTSFQGNS-FTDYINAVFVD-------GYTKPRE-YIATEWPLMMTQGEFW 366
           +P D+ R  L     N   +DYINA  +          +KP++ YIAT+  L  T  +FW
Sbjct: 283 LPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFW 342

Query: 367 SLVYDYECAAVVVLCVP--PKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            +V+  E + V+V+      +   +   +WP+    K+YG V  + +V  +   +     
Sbjct: 343 RMVFQ-ENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYG-VMRVRNVKESAAHDYTLRE 400

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR-T 483
            +++K          G     +TV  +    WP  H VPS    +++ +  V   ++   
Sbjct: 401 LKLSK---------VGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIM 450

Query: 484 DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCE 540
           D GPV V    G  R G +   +  I+ + + G   ++DV + ++ VR  R  +V+   +
Sbjct: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510

Query: 541 LK 542
            +
Sbjct: 511 YR 512


>D13540-1|BAA02740.2|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score =  126 bits (304), Expect = 5e-28
 Identities = 71/208 (34%), Positives = 112/208 (53%), Gaps = 12/208 (5%)

Query: 46  KPK-AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETY 104
           KPK +YI TQG  ++TV DFWRM++QE +  IVM TK  +  K  CV+YWP      E Y
Sbjct: 322 KPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKE-Y 380

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEF 163
           G + V  V+E    ++ +R  +L K  +G    ER + Q+H+  W  H  P     +L+F
Sbjct: 381 GVMRVRNVKESAAHDYTLRELKLSKVGQGNT--ERTVWQYHFRTWPDHGVPSDPGGVLDF 438

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEED---SFDVFGCL 220
                            AGP+VVHC+ G GR+G ++ ID  +++  E+      DV   +
Sbjct: 439 LEEVHHKQESIMD----AGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 494

Query: 221 KKLRESRKGLIENEEQYKFVYDTLEEHV 248
           + +R  R G+++ E QY+F+Y  ++ ++
Sbjct: 495 QMVRSQRSGMVQTEAQYRFIYMAVQHYI 522



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 71/302 (23%), Positives = 137/302 (45%), Gaps = 30/302 (9%)

Query: 258 SELSQRLKQKSQRDPVT-KLNE-YQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLV 315
           +E+  R+++ S+    T K+ + + +E++ + +Q  +        G R +N+ KNR   +
Sbjct: 224 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSR-KEGQRQENKNKNRYKNI 282

Query: 316 VPPDNFRPYLTSFQGNS-FTDYINAVFVD-------GYTKPRE-YIATEWPLMMTQGEFW 366
           +P D+ R  L     N   +DYINA  +          +KP++ YIAT+  L  T  +FW
Sbjct: 283 LPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFW 342

Query: 367 SLVYDYECAAVVVLCVP--PKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWI 424
            +V+  E + V+V+      +   +   +WP+    K+YG V  + +V  +   +     
Sbjct: 343 RMVFQ-ENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYG-VMRVRNVKESAAHDYTLRE 400

Query: 425 FRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQR-T 483
            +++K          G     +TV  +    WP  H VPS    +++ +  V   ++   
Sbjct: 401 LKLSK---------VGQGNTERTVWQYHFRTWP-DHGVPSDPGGVLDFLEEVHHKQESIM 450

Query: 484 DYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCE 540
           D GPV V    G  R G +   +  I+ + + G   ++DV + ++ VR  R  +V+   +
Sbjct: 451 DAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQ 510

Query: 541 LK 542
            +
Sbjct: 511 YR 512


>EF064714-1|ABK41897.1|  807|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 22 (lymphoid) protein.
          Length = 807

 Score =  124 bits (299), Expect = 2e-27
 Identities = 70/210 (33%), Positives = 105/210 (50%), Gaps = 15/210 (7%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAYI TQGP   T++DFWRMIW+     IVM    ++  K  C +YW    E 
Sbjct: 90  IKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEM 149

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              +G  SV    E+  +++ IRT ++         E R I QFHY  W  H  P S + 
Sbjct: 150 QLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS-----ETRTIYQFHYKNWPDHDVPSSIDP 204

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEE---EDSFDV 216
           +LE                    P+ +HC+ G GR+GV  AID    L ++    ++F V
Sbjct: 205 ILELIWDVRCYQEDDSV------PICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSV 258

Query: 217 FGCLKKLRESRKGLIENEEQYKFVYDTLEE 246
           F  ++++R  R  L++ +EQY+ VY+ + E
Sbjct: 259 FSLIREMRTQRPSLVQTQEQYELVYNAVLE 288



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 76/286 (26%), Positives = 134/286 (46%), Gaps = 24/286 (8%)

Query: 259 ELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDC---AGGHRGDNREKNRDVLV 315
           E+ Q+   ++Q   +TK  E+  E+ ++ +Q+ ++            +  N +KNR   +
Sbjct: 5   EILQKFLDEAQSKKITK-EEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDI 63

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +P D  R  L+    +  + YINA F+ G   P+ YIAT+ PL  T  +FW ++++Y   
Sbjct: 64  LPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVL 123

Query: 376 AVVVLCVP-PKNSQQYPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            +V+ C+      ++   +W E G    ++GP F++   +    ++   +I R       
Sbjct: 124 IIVMACMEYEMGKKKCERYWAEPGEMQLEFGP-FSVSCEAEKRKSD---YIIR------- 172

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
              L     + T+T+  F    WP  H VPSS + ++EL+  V R  Q  D  P+C+   
Sbjct: 173 --TLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDV-RCYQEDDSVPICIHCS 228

Query: 494 DGRSRAGVYCAAN---ACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            G  R GV CA +     ++  I      VF  ++ +R  RP LV+
Sbjct: 229 AGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQ 274


>AL137856-2|CAI19068.1|  807|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 22 (lymphoid) protein.
          Length = 807

 Score =  124 bits (299), Expect = 2e-27
 Identities = 70/210 (33%), Positives = 105/210 (50%), Gaps = 15/210 (7%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAYI TQGP   T++DFWRMIW+     IVM    ++  K  C +YW    E 
Sbjct: 90  IKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEM 149

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              +G  SV    E+  +++ IRT ++         E R I QFHY  W  H  P S + 
Sbjct: 150 QLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS-----ETRTIYQFHYKNWPDHDVPSSIDP 204

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEE---EDSFDV 216
           +LE                    P+ +HC+ G GR+GV  AID    L ++    ++F V
Sbjct: 205 ILELIWDVRCYQEDDSV------PICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSV 258

Query: 217 FGCLKKLRESRKGLIENEEQYKFVYDTLEE 246
           F  ++++R  R  L++ +EQY+ VY+ + E
Sbjct: 259 FSLIREMRTQRPSLVQTQEQYELVYNAVLE 288



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 76/286 (26%), Positives = 134/286 (46%), Gaps = 24/286 (8%)

Query: 259 ELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDC---AGGHRGDNREKNRDVLV 315
           E+ Q+   ++Q   +TK  E+  E+ ++ +Q+ ++            +  N +KNR   +
Sbjct: 5   EILQKFLDEAQSKKITK-EEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDI 63

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +P D  R  L+    +  + YINA F+ G   P+ YIAT+ PL  T  +FW ++++Y   
Sbjct: 64  LPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVL 123

Query: 376 AVVVLCVP-PKNSQQYPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            +V+ C+      ++   +W E G    ++GP F++   +    ++   +I R       
Sbjct: 124 IIVMACMEYEMGKKKCERYWAEPGEMQLEFGP-FSVSCEAEKRKSD---YIIR------- 172

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
              L     + T+T+  F    WP  H VPSS + ++EL+  V R  Q  D  P+C+   
Sbjct: 173 --TLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDV-RCYQEDDSVPICIHCS 228

Query: 494 DGRSRAGVYCAAN---ACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            G  R GV CA +     ++  I      VF  ++ +R  RP LV+
Sbjct: 229 AGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQ 274


>AF150732-1|AAF67472.1|  799|Homo sapiens protein tyrosine
           phosphatase protein.
          Length = 799

 Score =  123 bits (296), Expect = 4e-27
 Identities = 69/210 (32%), Positives = 105/210 (50%), Gaps = 15/210 (7%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  P+AYI TQGP   T++DFWRMIW+     IVM    ++  K  C +YW    E 
Sbjct: 90  IKGVYGPEAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEM 149

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              +G  SV    E+  +++ IRT ++         E R I QFHY  W  H  P S + 
Sbjct: 150 QLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS-----ETRTIYQFHYKNWPDHDVPSSIDP 204

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEE---EDSFDV 216
           +LE                    P+ +HC+ G GR+GV  AID    L ++    ++F V
Sbjct: 205 ILELIWDVRCTQEDDSV------PICIHCSAGCGRTGVICAIDYTWMLLKDGIIPENFSV 258

Query: 217 FGCLKKLRESRKGLIENEEQYKFVYDTLEE 246
           F  ++++R  R  L++ +EQY+ VY+ + E
Sbjct: 259 FSLIREMRTQRPSLVQTQEQYELVYNAVLE 288



 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 76/286 (26%), Positives = 133/286 (46%), Gaps = 24/286 (8%)

Query: 259 ELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDC---AGGHRGDNREKNRDVLV 315
           E+ Q+   ++Q   +TK  E+  E+ ++ +Q+ ++            +  N +KNR   +
Sbjct: 5   EILQKFLDEAQSKKITK-EEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDI 63

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +P D  R  L+    +  + YINA F+ G   P  YIAT+ PL  T  +FW ++++Y   
Sbjct: 64  LPYDYSRVELSLITSDEDSSYINANFIKGVYGPEAYIATQGPLSTTLLDFWRMIWEYSVL 123

Query: 376 AVVVLCVP-PKNSQQYPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            +V+ C+      ++   +W E G    ++GP F++   +    ++   +I R       
Sbjct: 124 IIVMACMEYEMGKKKCERYWAEPGEMQLEFGP-FSVSCEAEKRKSD---YIIR------- 172

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
              L     + T+T+  F    WP  H VPSS + ++EL+  V R  Q  D  P+C+   
Sbjct: 173 --TLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDV-RCTQEDDSVPICIHCS 228

Query: 494 DGRSRAGVYCAAN---ACIEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            G  R GV CA +     ++  I      VF  ++ +R  RP LV+
Sbjct: 229 AGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQ 274


>M93425-1|AAA36529.1|  780|Homo sapiens protein tyrosine phosphatase
           protein.
          Length = 780

 Score =  122 bits (295), Expect = 6e-27
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 13/209 (6%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAY+ TQGP  +TV+DFWRMIW+     IVM  + F+  +  C +YWP   E 
Sbjct: 94  IKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGED 153

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             T+    +    E+   ++FIRT  L         E R + QFHY  W  H  P S   
Sbjct: 154 PITFAPFKISCEDEQARTDYFIRTLLLEFQN-----ESRRLYQFHYVNWPDHDVPSS--- 205

Query: 161 LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN---LELAEEEDSFDVF 217
             F                   P+ +HC+ G GR+G   AID     L+  +  + F+VF
Sbjct: 206 --FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVF 263

Query: 218 GCLKKLRESRKGLIENEEQYKFVYDTLEE 246
             ++++R  R   ++ +EQY+ V+  + +
Sbjct: 264 NLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 62/242 (25%), Positives = 118/242 (48%), Gaps = 18/242 (7%)

Query: 299 AGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPL 358
           A G + +N +KNR   ++P D+ R  LT    +  +DYINA F+ G   P+ Y+AT+ PL
Sbjct: 51  ATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPL 110

Query: 359 MMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYT 418
             T  +FW ++++Y    +V+ C           F    +  ++Y P++  D ++   + 
Sbjct: 111 ANTVIDFWRMIWEYNVVIIVMAC---------REFEMGRKKCERYWPLYGEDPITFAPF- 160

Query: 419 NIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVER 478
            I     +        T L+   +  ++ +  F    WP  H VPSS +S++++++++ +
Sbjct: 161 KISCEDEQARTDYFIRT-LLLEFQNESRRLYQFHYVNWP-DHDVPSSFDSILDMISLMRK 218

Query: 479 WRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG----EVDVFQAVKTVRRHRPQL 534
           +++  D  P+C+    G  R G  CA +     ++K G    E +VF  ++ +R  R   
Sbjct: 219 YQEHEDV-PICIHCSAGCGRTGAICAID-YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSA 276

Query: 535 VE 536
           V+
Sbjct: 277 VQ 278


>BC050008-1|AAH50008.2|  780|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 12 protein.
          Length = 780

 Score =  122 bits (295), Expect = 6e-27
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 13/209 (6%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAY+ TQGP  +TV+DFWRMIW+     IVM  + F+  +  C +YWP   E 
Sbjct: 94  IKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGED 153

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             T+    +    E+   ++FIRT  L         E R + QFHY  W  H  P S   
Sbjct: 154 PITFAPFKISCEDEQARTDYFIRTLLLEFQN-----ESRRLYQFHYVNWPDHDVPSS--- 205

Query: 161 LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN---LELAEEEDSFDVF 217
             F                   P+ +HC+ G GR+G   AID     L+  +  + F+VF
Sbjct: 206 --FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVF 263

Query: 218 GCLKKLRESRKGLIENEEQYKFVYDTLEE 246
             ++++R  R   ++ +EQY+ V+  + +
Sbjct: 264 NLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 62/242 (25%), Positives = 118/242 (48%), Gaps = 18/242 (7%)

Query: 299 AGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPL 358
           A G + +N +KNR   ++P D+ R  LT    +  +DYINA F+ G   P+ Y+AT+ PL
Sbjct: 51  ATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPL 110

Query: 359 MMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYT 418
             T  +FW ++++Y    +V+ C           F    +  ++Y P++  D ++   + 
Sbjct: 111 ANTVIDFWRMIWEYNVVIIVMAC---------REFEMGRKKCERYWPLYGEDPITFAPF- 160

Query: 419 NIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVER 478
            I     +        T L+   +  ++ +  F    WP  H VPSS +S++++++++ +
Sbjct: 161 KISCEDEQARTDYFIRT-LLLEFQNESRRLYQFHYVNWP-DHDVPSSFDSILDMISLMRK 218

Query: 479 WRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG----EVDVFQAVKTVRRHRPQL 534
           +++  D  P+C+    G  R G  CA +     ++K G    E +VF  ++ +R  R   
Sbjct: 219 YQEHEDV-PICIHCSAGCGRTGAICAID-YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSA 276

Query: 535 VE 536
           V+
Sbjct: 277 VQ 278


>AC006451-1|AAQ96881.1|  780|Homo sapiens unknown protein.
          Length = 780

 Score =  122 bits (295), Expect = 6e-27
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 13/209 (6%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAY+ TQGP  +TV+DFWRMIW+     IVM  + F+  +  C +YWP   E 
Sbjct: 94  IKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGED 153

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             T+    +    E+   ++FIRT  L         E R + QFHY  W  H  P S   
Sbjct: 154 PITFAPFKISCEDEQARTDYFIRTLLLEFQN-----ESRRLYQFHYVNWPDHDVPSS--- 205

Query: 161 LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN---LELAEEEDSFDVF 217
             F                   P+ +HC+ G GR+G   AID     L+  +  + F+VF
Sbjct: 206 --FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVF 263

Query: 218 GCLKKLRESRKGLIENEEQYKFVYDTLEE 246
             ++++R  R   ++ +EQY+ V+  + +
Sbjct: 264 NLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 62/242 (25%), Positives = 118/242 (48%), Gaps = 18/242 (7%)

Query: 299 AGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPL 358
           A G + +N +KNR   ++P D+ R  LT    +  +DYINA F+ G   P+ Y+AT+ PL
Sbjct: 51  ATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPL 110

Query: 359 MMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYT 418
             T  +FW ++++Y    +V+ C           F    +  ++Y P++  D ++   + 
Sbjct: 111 ANTVIDFWRMIWEYNVVIIVMAC---------REFEMGRKKCERYWPLYGEDPITFAPF- 160

Query: 419 NIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVER 478
            I     +        T L+   +  ++ +  F    WP  H VPSS +S++++++++ +
Sbjct: 161 KISCEDEQARTDYFIRT-LLLEFQNESRRLYQFHYVNWP-DHDVPSSFDSILDMISLMRK 218

Query: 479 WRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG----EVDVFQAVKTVRRHRPQL 534
           +++  D  P+C+    G  R G  CA +     ++K G    E +VF  ++ +R  R   
Sbjct: 219 YQEHEDV-PICIHCSAGCGRTGAICAID-YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSA 276

Query: 535 VE 536
           V+
Sbjct: 277 VQ 278


>AB209524-1|BAD92761.1|  807|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 12 variant protein.
          Length = 807

 Score =  122 bits (295), Expect = 6e-27
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 13/209 (6%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAY+ TQGP  +TV+DFWRMIW+     IVM  + F+  +  C +YWP   E 
Sbjct: 121 IKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGED 180

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             T+    +    E+   ++FIRT  L         E R + QFHY  W  H  P S   
Sbjct: 181 PITFAPFKISCEDEQARTDYFIRTLLLEFQN-----ESRRLYQFHYVNWPDHDVPSS--- 232

Query: 161 LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN---LELAEEEDSFDVF 217
             F                   P+ +HC+ G GR+G   AID     L+  +  + F+VF
Sbjct: 233 --FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVF 290

Query: 218 GCLKKLRESRKGLIENEEQYKFVYDTLEE 246
             ++++R  R   ++ +EQY+ V+  + +
Sbjct: 291 NLIQEMRTQRHSAVQTKEQYELVHRAIAQ 319



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 62/242 (25%), Positives = 118/242 (48%), Gaps = 18/242 (7%)

Query: 299 AGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPL 358
           A G + +N +KNR   ++P D+ R  LT    +  +DYINA F+ G   P+ Y+AT+ PL
Sbjct: 78  ATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPL 137

Query: 359 MMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYT 418
             T  +FW ++++Y    +V+ C           F    +  ++Y P++  D ++   + 
Sbjct: 138 ANTVIDFWRMIWEYNVVIIVMAC---------REFEMGRKKCERYWPLYGEDPITFAPF- 187

Query: 419 NIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVER 478
            I     +        T L+   +  ++ +  F    WP  H VPSS +S++++++++ +
Sbjct: 188 KISCEDEQARTDYFIRT-LLLEFQNESRRLYQFHYVNWP-DHDVPSSFDSILDMISLMRK 245

Query: 479 WRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG----EVDVFQAVKTVRRHRPQL 534
           +++  D  P+C+    G  R G  CA +     ++K G    E +VF  ++ +R  R   
Sbjct: 246 YQEHEDV-PICIHCSAGCGRTGAICAID-YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSA 303

Query: 535 VE 536
           V+
Sbjct: 304 VQ 305


>D13380-1|BAA02648.1|  780|Homo sapiens protein tyrosine phosphatase
           G1 protein.
          Length = 780

 Score =  122 bits (294), Expect = 7e-27
 Identities = 64/209 (30%), Positives = 100/209 (47%), Gaps = 13/209 (6%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAY+ TQGP  +TV+DFWRM+W+     IVM  + F+  +  C +YWP   E 
Sbjct: 94  IKGVYGPKAYVATQGPLANTVIDFWRMVWEYNVVIIVMACREFEMGRKKCERYWPLYGED 153

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNAL 160
             T+    +    E+   ++FIRT  L         E R + QFHY  W  H  P S   
Sbjct: 154 PITFAPFKISCEDEQARTDYFIRTLLLEFQN-----ESRRLYQFHYVNWPDHDVPSS--- 205

Query: 161 LEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDAN---LELAEEEDSFDVF 217
             F                   P+ +HC+ G GR+G   AID     L+  +  + F+VF
Sbjct: 206 --FDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVF 263

Query: 218 GCLKKLRESRKGLIENEEQYKFVYDTLEE 246
             ++++R  R   ++ +EQY+ V+  + +
Sbjct: 264 NLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292



 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 63/242 (26%), Positives = 118/242 (48%), Gaps = 18/242 (7%)

Query: 299 AGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPL 358
           A G + +N +KNR   ++P D+ R  LT    +  +DYINA F+ G   P+ Y+AT+ PL
Sbjct: 51  ATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPL 110

Query: 359 MMTQGEFWSLVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYT 418
             T  +FW +V++Y    +V+ C           F    +  ++Y P++  D ++   + 
Sbjct: 111 ANTVIDFWRMVWEYNVVIIVMAC---------REFEMGRKKCERYWPLYGEDPITFAPF- 160

Query: 419 NIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVER 478
            I     +        T L+   +  ++ +  F    WP  H VPSS +S++++++++ +
Sbjct: 161 KISCEDEQARTDYFIRT-LLLEFQNESRRLYQFHYVNWP-DHDVPSSFDSILDMISLMRK 218

Query: 479 WRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHG----EVDVFQAVKTVRRHRPQL 534
           +++  D  P+C+    G  R G  CA +     ++K G    E +VF  ++ +R  R   
Sbjct: 219 YQEHEDV-PICIHCSAGCGRTGAICAID-YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSA 276

Query: 535 VE 536
           V+
Sbjct: 277 VQ 278


>M25393-1|AAA65997.1|  415|Homo sapiens protein tyrosine phosphatase
           protein.
          Length = 415

 Score =  120 bits (290), Expect = 2e-26
 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 16/228 (7%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK---DETY 104
           ++YI+TQGP  +T   FW M+WQ++  A+VML +  +   V C QYWP + ++    ET 
Sbjct: 81  RSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKET- 139

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEF 163
              SV ++ E+  + + +   +L     G   E R I  FHYT W     P S A  L F
Sbjct: 140 -GFSVKLLSEDVKSYYTVHLLQLENINSG---ETRTISHFHYTTWPDFGVPESPASFLNF 195

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKL 223
                         NP  GP V+HC+ G GRSG +  +D  L L E+ D  ++   L  +
Sbjct: 196 ----LFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNM 251

Query: 224 RESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRD 271
           R+ R GLI+  +Q +F Y  + E   C I     S + +R K+ S+ D
Sbjct: 252 RKYRMGLIQTPDQLRFSYMAIIEGAKC-IK--GDSSIQKRWKELSKED 296



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 65/241 (26%), Positives = 115/241 (47%), Gaps = 18/241 (7%)

Query: 305 DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
           +NR +NR   V P D+ R  L     N+  DYINA  VD     R YI T+ PL  T   
Sbjct: 41  ENRNRNRYRDVSPYDHSRVKLQ----NAENDYINASLVDIEEAQRSYILTQGPLPNTCCH 96

Query: 365 FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV-FTIDHVSHNHYTNIKT 422
           FW +V+  +  AVV+L  +  K S +   +WP       +    F++  +S +    +K+
Sbjct: 97  FWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED----VKS 152

Query: 423 WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQ 481
           + + ++  ++ L  + +G    T+T+  F  T WP    VP S  S +  L  + E    
Sbjct: 153 Y-YTVH--LLQLENINSG---ETRTISHFHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205

Query: 482 RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCEL 541
             D+GP  +    G  R+G +   + C+  + K  ++++ Q +  +R++R  L++   +L
Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265

Query: 542 K 542
           +
Sbjct: 266 R 266


>BC016727-1|AAH16727.1|  353|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 2 protein.
          Length = 353

 Score =  120 bits (290), Expect = 2e-26
 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 16/228 (7%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK---DETY 104
           ++YI+TQGP  +T   FW M+WQ++  A+VML +  +   V C QYWP + ++    ET 
Sbjct: 81  RSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKET- 139

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEF 163
              SV ++ E+  + + +   +L     G   E R I  FHYT W     P S A  L F
Sbjct: 140 -GFSVKLLSEDVKSYYTVHLLQLENINSG---ETRTISHFHYTTWPDFGVPESPASFLNF 195

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKL 223
                         NP  GP V+HC+ G GRSG +  +D  L L E+ D  ++   L  +
Sbjct: 196 ----LFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNM 251

Query: 224 RESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRD 271
           R+ R GLI+  +Q +F Y  + E   C I     S + +R K+ S+ D
Sbjct: 252 RKYRMGLIQTPDQLRFSYMAIIEGAKC-IK--GDSSIQKRWKELSKED 296



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 65/241 (26%), Positives = 115/241 (47%), Gaps = 18/241 (7%)

Query: 305 DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
           +NR +NR   V P D+ R  L     N+  DYINA  VD     R YI T+ PL  T   
Sbjct: 41  ENRNRNRYRDVSPYDHSRVKLQ----NAENDYINASLVDIEEAQRSYILTQGPLPNTCCH 96

Query: 365 FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV-FTIDHVSHNHYTNIKT 422
           FW +V+  +  AVV+L  +  K S +   +WP       +    F++  +S +    +K+
Sbjct: 97  FWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED----VKS 152

Query: 423 WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQ 481
           + + ++  ++ L  + +G    T+T+  F  T WP    VP S  S +  L  + E    
Sbjct: 153 Y-YTVH--LLQLENINSG---ETRTISHFHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205

Query: 482 RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCEL 541
             D+GP  +    G  R+G +   + C+  + K  ++++ Q +  +R++R  L++   +L
Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265

Query: 542 K 542
           +
Sbjct: 266 R 266


>BC008244-1|AAH08244.1|  387|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 2 protein.
          Length = 387

 Score =  120 bits (290), Expect = 2e-26
 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 16/228 (7%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK---DETY 104
           ++YI+TQGP  +T   FW M+WQ++  A+VML +  +   V C QYWP + ++    ET 
Sbjct: 81  RSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKET- 139

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEF 163
              SV ++ E+  + + +   +L     G   E R I  FHYT W     P S A  L F
Sbjct: 140 -GFSVKLLSEDVKSYYTVHLLQLENINSG---ETRTISHFHYTTWPDFGVPESPASFLNF 195

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKL 223
                         NP  GP V+HC+ G GRSG +  +D  L L E+ D  ++   L  +
Sbjct: 196 ----LFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNM 251

Query: 224 RESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRD 271
           R+ R GLI+  +Q +F Y  + E   C I     S + +R K+ S+ D
Sbjct: 252 RKYRMGLIQTPDQLRFSYMAIIEGAKC-IK--GDSSIQKRWKELSKED 296



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 65/241 (26%), Positives = 115/241 (47%), Gaps = 18/241 (7%)

Query: 305 DNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGE 364
           +NR +NR   V P D+ R  L     N+  DYINA  VD     R YI T+ PL  T   
Sbjct: 41  ENRNRNRYRDVSPYDHSRVKLQ----NAENDYINASLVDIEEAQRSYILTQGPLPNTCCH 96

Query: 365 FWSLVYDYECAAVVVLC-VPPKNSQQYPPFWPEGRHSKKYGPV-FTIDHVSHNHYTNIKT 422
           FW +V+  +  AVV+L  +  K S +   +WP       +    F++  +S +    +K+
Sbjct: 97  FWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED----VKS 152

Query: 423 WIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQ 481
           + + ++  ++ L  + +G    T+T+  F  T WP    VP S  S +  L  + E    
Sbjct: 153 Y-YTVH--LLQLENINSG---ETRTISHFHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205

Query: 482 RTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCEL 541
             D+GP  +    G  R+G +   + C+  + K  ++++ Q +  +R++R  L++   +L
Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265

Query: 542 K 542
           +
Sbjct: 266 R 266


>AB209569-1|BAD92806.1|  392|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 2 isoform 1 variant
           protein.
          Length = 392

 Score =  120 bits (290), Expect = 2e-26
 Identities = 76/228 (33%), Positives = 113/228 (49%), Gaps = 16/228 (7%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK---DETY 104
           ++YI+TQGP  +T   FW M+WQ++  A+VML +  +   V C QYWP + ++    ET 
Sbjct: 58  RSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKET- 116

Query: 105 GDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEF 163
              SV ++ E+  + + +   +L     G   E R I  FHYT W     P S A  L F
Sbjct: 117 -GFSVKLLSEDVKSYYTVHLLQLENINSG---ETRTISHFHYTTWPDFGVPESPASFLNF 172

Query: 164 XXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKL 223
                         NP  GP V+HC+ G GRSG +  +D  L L E+ D  ++   L  +
Sbjct: 173 ----LFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNM 228

Query: 224 RESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRD 271
           R+ R GLI+  +Q +F Y  + E   C I     S + +R K+ S+ D
Sbjct: 229 RKYRMGLIQTPDQLRFSYMAIIEGAKC-IK--GDSSIQKRWKELSKED 273



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 56/215 (26%), Positives = 103/215 (47%), Gaps = 14/215 (6%)

Query: 331 NSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQQ 389
           N+  DYINA  VD     R YI T+ PL  T   FW +V+  +  AVV+L  +  K S +
Sbjct: 40  NAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVK 99

Query: 390 YPPFWPEGRHSKKYGPV-FTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
              +WP       +    F++  +S +    +K++ + ++  ++ L  + +G    T+T+
Sbjct: 100 CAQYWPTDDQEMLFKETGFSVKLLSED----VKSY-YTVH--LLQLENINSG---ETRTI 149

Query: 449 QLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F  T WP    VP S  S +  L  + E      D+GP  +    G  R+G +   + 
Sbjct: 150 SHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDT 208

Query: 508 CIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELK 542
           C+  + K  ++++ Q +  +R++R  L++   +L+
Sbjct: 209 CLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLR 243


>D11327-1|BAA01946.1|  360|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 360

 Score =  120 bits (289), Expect = 3e-26
 Identities = 68/199 (34%), Positives = 100/199 (50%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 161 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 216

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 217 PFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 270

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 271 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 328

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+ +EQY+F++ TL
Sbjct: 329 DRGGMIQTDEQYQFLHHTL 347



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 122 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 181

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I         ++K      
Sbjct: 182 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQI------RIQDMK------ 226

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
                ++ +L    +   ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 227 ECPEYTVRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 285

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 286 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTDEQYQ 341

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 342 FLHHTLALYAGQLPEEPSP 360


>AF001847-1|AAD00905.1|  692|Homo sapiens lymphoid phosphatase LyP2
           protein.
          Length = 692

 Score =  120 bits (288), Expect = 4e-26
 Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 16/211 (7%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAYI TQGP   T++DFWRMIW+     IVM    ++  K  C +YW    E 
Sbjct: 90  IKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEM 149

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              +G  SV    E+  +++ IRT ++         E R I QFHY  W  H  P S + 
Sbjct: 150 QLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS-----ETRTIYQFHYKNWPDHDVPSSIDP 204

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAI-DANLELAEE---EDSFD 215
           +LE                    P+ +HC+ G GR+GV  AI D    L ++    ++F 
Sbjct: 205 ILELIWDVRCYQEDDSV------PICIHCSAGCGRTGVICAIVDYTWMLLKDGIIPENFS 258

Query: 216 VFGCLKKLRESRKGLIENEEQYKFVYDTLEE 246
           VF  ++++R  R  L++ +EQY+ VY+ + E
Sbjct: 259 VFSLIREMRTQRPSLVQTQEQYELVYNAVLE 289



 Score =  101 bits (241), Expect = 2e-20
 Identities = 77/287 (26%), Positives = 134/287 (46%), Gaps = 25/287 (8%)

Query: 259 ELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDC---AGGHRGDNREKNRDVLV 315
           E+ Q+   ++Q   +TK  E+  E+ ++ +Q+ ++               N +KNR   +
Sbjct: 5   EILQKFLDEAQSKKITK-EEFANEFLKLKRQSTKYKADKTYPTTVAENAKNIKKNRYKDI 63

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +P D  R  L+    +  + YINA F+ G   P+ YIAT+ PL  T  +FW ++++Y   
Sbjct: 64  LPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVL 123

Query: 376 AVVVLCVP-PKNSQQYPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            +V+ C+      ++   +W E G    ++GP F++   +    ++   +I R       
Sbjct: 124 IIVMACMEYEMGKKKCERYWAEPGEMQLEFGP-FSVSCEAEKRKSD---YIIR------- 172

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
              L     + T+T+  F    WP  H VPSS + ++EL+  V R  Q  D  P+C+   
Sbjct: 173 --TLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDV-RCYQEDDSVPICIHCS 228

Query: 494 DGRSRAGVYCAANACIEQVIKHGEV----DVFQAVKTVRRHRPQLVE 536
            G  R GV CA       ++K G +     VF  ++ +R  RP LV+
Sbjct: 229 AGCGRTGVICAIVDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQ 275


>AF001846-1|AAD00904.1|  808|Homo sapiens lymphoid phosphatase LyP1
           protein.
          Length = 808

 Score =  120 bits (288), Expect = 4e-26
 Identities = 70/211 (33%), Positives = 105/211 (49%), Gaps = 16/211 (7%)

Query: 41  LKSLLKPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEK 100
           +K +  PKAYI TQGP   T++DFWRMIW+     IVM    ++  K  C +YW    E 
Sbjct: 90  IKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEM 149

Query: 101 DETYGDISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NA 159
              +G  SV    E+  +++ IRT ++         E R I QFHY  W  H  P S + 
Sbjct: 150 QLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS-----ETRTIYQFHYKNWPDHDVPSSIDP 204

Query: 160 LLEFXXXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAI-DANLELAEE---EDSFD 215
           +LE                    P+ +HC+ G GR+GV  AI D    L ++    ++F 
Sbjct: 205 ILELIWDVRCYQEDDSV------PICIHCSAGCGRTGVICAIVDYTWMLLKDGIIPENFS 258

Query: 216 VFGCLKKLRESRKGLIENEEQYKFVYDTLEE 246
           VF  ++++R  R  L++ +EQY+ VY+ + E
Sbjct: 259 VFSLIREMRTQRPSLVQTQEQYELVYNAVLE 289



 Score =  101 bits (241), Expect = 2e-20
 Identities = 77/287 (26%), Positives = 134/287 (46%), Gaps = 25/287 (8%)

Query: 259 ELSQRLKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDC---AGGHRGDNREKNRDVLV 315
           E+ Q+   ++Q   +TK  E+  E+ ++ +Q+ ++               N +KNR   +
Sbjct: 5   EILQKFLDEAQSKKITK-EEFANEFLKLKRQSTKYKADKTYPTTVAENAKNIKKNRYKDI 63

Query: 316 VPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECA 375
           +P D  R  L+    +  + YINA F+ G   P+ YIAT+ PL  T  +FW ++++Y   
Sbjct: 64  LPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEYSVL 123

Query: 376 AVVVLCVP-PKNSQQYPPFWPE-GRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIIS 433
            +V+ C+      ++   +W E G    ++GP F++   +    ++   +I R       
Sbjct: 124 IIVMACMEYEMGKKKCERYWAEPGEMQLEFGP-FSVSCEAEKRKSD---YIIR------- 172

Query: 434 LTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDYGPVCVVSP 493
              L     + T+T+  F    WP  H VPSS + ++EL+  V R  Q  D  P+C+   
Sbjct: 173 --TLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDV-RCYQEDDSVPICIHCS 228

Query: 494 DGRSRAGVYCAANACIEQVIKHGEV----DVFQAVKTVRRHRPQLVE 536
            G  R GV CA       ++K G +     VF  ++ +R  RP LV+
Sbjct: 229 AGCGRTGVICAIVDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQ 275


>BT009848-1|AAP88850.1|  360|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 7 protein.
          Length = 360

 Score =  119 bits (286), Expect = 7e-26
 Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 161 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 216

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 217 PFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 270

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 271 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 328

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+  EQY+F++ TL
Sbjct: 329 DRGGMIQTAEQYQFLHHTL 347



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 122 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 181

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I         ++K      
Sbjct: 182 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQI------RIQDMK------ 226

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
                ++ +L    +   ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 227 ECPEYTVRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 285

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 286 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTAEQYQ 341

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 342 FLHHTLALYAGQLPEEPSP 360


>BC001746-1|AAH01746.2|  399|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 7 protein.
          Length = 399

 Score =  119 bits (286), Expect = 7e-26
 Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 200 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 255

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 256 PFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 309

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 310 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 367

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+  EQY+F++ TL
Sbjct: 368 DRGGMIQTAEQYQFLHHTL 386



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 161 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 220

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I         ++K      
Sbjct: 221 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQI------RIQDMK------ 265

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
                ++ +L    +   ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 266 ECPEYTVRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 324

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 325 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTAEQYQ 380

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 381 FLHHTLALYAGQLPEEPSP 399


>AL592300-4|CAI13109.1|  465|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 7 protein.
          Length = 465

 Score =  119 bits (286), Expect = 7e-26
 Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 266 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 321

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 322 PFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 375

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 376 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 433

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+  EQY+F++ TL
Sbjct: 434 DRGGMIQTAEQYQFLHHTL 452



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 227 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 286

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I         ++K      
Sbjct: 287 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQI------RIQDMK------ 331

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
                ++ +L    +   ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 332 ECPEYTVRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 390

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 391 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTAEQYQ 446

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 447 FLHHTLALYAGQLPEEPSP 465


>AL592300-3|CAI13108.1|  399|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 7 protein.
          Length = 399

 Score =  119 bits (286), Expect = 7e-26
 Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 200 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 255

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 256 PFQIRIQDMKECPEYTVRQLTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 309

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 310 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 367

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+  EQY+F++ TL
Sbjct: 368 DRGGMIQTAEQYQFLHHTL 386



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/259 (25%), Positives = 111/259 (42%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 161 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 220

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I         ++K      
Sbjct: 221 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQI------RIQDMK------ 265

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
                ++ +L    +   ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 266 ECPEYTVRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 324

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 325 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTAEQYQ 380

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 381 FLHHTLALYAGQLPEEPSP 399


>Y08569-1|CAA69880.1| 1015|Homo sapiens Islet Cell Autoantigen Releted
            protein.
          Length = 1015

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49   AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
            AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 815  AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 872

Query: 109  VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
            V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 873  VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 926

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                          + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 927  ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 983

Query: 226  SRKGLIENEEQYKFVYDTLEEHV 248
             R G+++ +EQ++F    + E V
Sbjct: 984  QRPGMVQTKEQFEFALTAVAEEV 1006



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271  DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
            D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 737  DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 794

Query: 331  NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
            +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 795  HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 854

Query: 389  QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
            Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 855  QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 903

Query: 449  QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
              F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 904  TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 960

Query: 508  CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
             + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 961  VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 1015


>U81561-1|AAB68603.1|  998|Homo sapiens protein tyrosine phosphatase
           receptor pi protein.
          Length = 998

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 798 AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 855

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 856 VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 909

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 910 ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 966

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R G+++ +EQ++F    + E V
Sbjct: 967 QRPGMVQTKEQFEFALTAVAEEV 989



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 720 DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 777

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
           +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 778 HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 837

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 838 QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 886

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 887 TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 943

Query: 508 CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 944 VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 998


>U66702-1|AAC50742.1| 1015|Homo sapiens phogrin protein.
          Length = 1015

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49   AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
            AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 815  AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 872

Query: 109  VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
            V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 873  VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 926

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                          + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 927  ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 983

Query: 226  SRKGLIENEEQYKFVYDTLEEHV 248
             R G+++ +EQ++F    + E V
Sbjct: 984  QRPGMVQTKEQFEFALTAVAEEV 1006



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271  DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
            D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 737  DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 794

Query: 331  NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
            +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 795  HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 854

Query: 389  QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
            Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 855  QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 903

Query: 449  QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
              F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 904  TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 960

Query: 508  CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
             + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 961  VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 1015


>U65065-1|AAC51643.1|  986|Homo sapiens tyrosine phosphatase
           IA-2beta protein.
          Length = 986

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 786 AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 843

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 844 VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 897

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 898 ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 954

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R G+++ +EQ++F    + E V
Sbjct: 955 QRPGMVQTKEQFEFALTAVAEEV 977



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 708 DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 765

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
           +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 766 HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 825

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 826 QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 874

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 875 TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 931

Query: 508 CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 932 VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 986


>BC034040-1|AAH34040.1|  986|Homo sapiens protein tyrosine
           phosphatase, receptor type, N polypeptide 2 protein.
          Length = 986

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 786 AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 843

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 844 VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 897

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 898 ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 954

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R G+++ +EQ++F    + E V
Sbjct: 955 QRPGMVQTKEQFEFALTAVAEEV 977



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 708 DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 765

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
           +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 766 HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 825

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 826 QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 874

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 875 TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 931

Query: 508 CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 932 VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 986


>AF007555-1|AAB63600.1| 1015|Homo sapiens IAR/receptor-like
            protein-tyrosine phosphatase precursor protein.
          Length = 1015

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49   AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
            AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 815  AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 872

Query: 109  VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
            V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 873  VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 926

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                          + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 927  ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 983

Query: 226  SRKGLIENEEQYKFVYDTLEEHV 248
             R G+++ +EQ++F    + E V
Sbjct: 984  QRPGMVQTKEQFEFALTAVAEEV 1006



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271  DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
            D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 737  DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 794

Query: 331  NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
            +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 795  HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 854

Query: 389  QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
            Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 855  QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 903

Query: 449  QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
              F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 904  TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 960

Query: 508  CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
             + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 961  VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 1015


>AB002385-1|BAA20841.2| 1042|Homo sapiens KIAA0387 protein.
          Length = 1042

 Score =  118 bits (285), Expect = 9e-26
 Identities = 69/203 (33%), Positives = 102/203 (50%), Gaps = 14/203 (6%)

Query: 49   AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
            AYI TQGP   TV DFW+M+W+     IVMLT   +     C  YWP   E    Y    
Sbjct: 842  AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWP--DEGSNLYHIYE 899

Query: 109  VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSN-ALLEFXXX 166
            V +V E     +F +R+F L   +     E R + QFH+  W+    P S+ +LL+F   
Sbjct: 900  VNLVSEHIWCEDFLVRSFYLKNLQTN---ETRTVTQFHFLSWYDRGVPSSSRSLLDF--- 953

Query: 167  XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                          + P++VHC+DG GRSG Y+ ID  L ++A+     D+   L+ LR+
Sbjct: 954  ---RRKVNKCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHLRD 1010

Query: 226  SRKGLIENEEQYKFVYDTLEEHV 248
             R G+++ +EQ++F    + E V
Sbjct: 1011 QRPGMVQTKEQFEFALTAVAEEV 1033



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 78/295 (26%), Positives = 133/295 (45%), Gaps = 20/295 (6%)

Query: 271  DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
            D +   N  +KE++ +C           A   R +N  KNR + V+  D+ R  L +   
Sbjct: 764  DHLKNKNRLEKEWEALCAYQAEPNSSFVA--QREENVPKNRSLAVLTYDHSRVLLKAENS 821

Query: 331  NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-Q 388
            +S +DYINA   +D   +   YIAT+ PL  T  +FW +V++  C  +V+L    +N  +
Sbjct: 822  HSHSDYINASPIMDHDPRNPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVR 881

Query: 389  QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
            Q   +WP+   S  Y  ++ ++ VS +       W      +   L  L       T+TV
Sbjct: 882  QCYHYWPD-EGSNLY-HIYEVNLVSEH------IWCEDFLVRSFYLKNLQTN---ETRTV 930

Query: 449  QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
              F    W     VPSS+ SL++    V + +R R+   P+ V   DG  R+G Y   + 
Sbjct: 931  TQFHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRSGTYVLIDM 987

Query: 508  CIEQVIKHG-EVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
             + ++ K   E+D+   ++ +R  RP +V+   + +  L  +     A L   P+
Sbjct: 988  VLNKMAKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVNAILKALPQ 1042


>M64322-1|AAA59531.1|  339|Homo sapiens protein tyrosine phosphatase
           protein.
          Length = 339

 Score =  118 bits (284), Expect = 1e-25
 Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 12/199 (6%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K K YI TQGP  +TV DFW M+WQE  + IVMLT+  +  K  CV YWP    ++ETYG
Sbjct: 140 KEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREG-KEKCVHYWPT---EEETYG 195

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXX 165
              + I   +E   + +R   +   E     E R +    ++ W  H  P S   L    
Sbjct: 196 PFQIRIQDMKECPEYTVRHVTIQYQE-----ERRSVKHILFSAWPDHQTPESAGPL-LRL 249

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRE 225
                       +P  GP+VVHC+ G GR+G ++A     +  +     D+ G + +LR 
Sbjct: 250 VAEVEESPETAAHP--GPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRL 307

Query: 226 SRKGLIENEEQYKFVYDTL 244
            R G+I+  EQY+F++ TL
Sbjct: 308 DRGGMIQTAEQYQFLHHTL 326



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 67/259 (25%), Positives = 107/259 (41%), Gaps = 22/259 (8%)

Query: 309 KNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWS 367
           K+R   ++P    R  L   Q     DYINA ++ GY  K + YIAT+ P+  T  +FW 
Sbjct: 101 KDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWE 160

Query: 368 LVYDYECAAVVVLCVPPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRI 427
           +V+  E + +V+L    +  ++   +WP     + YGP F I               + +
Sbjct: 161 MVWQEEVSLIVMLTQLREGKEKCVHYWP--TEEETYGP-FQIRIQDMKECPE-----YTV 212

Query: 428 NKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-G 486
               I   E         ++V+    + WP  H+ P S   L+ L+  VE   +   + G
Sbjct: 213 RHVTIQYQE-------ERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG 264

Query: 487 PVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRPQLVENMCELKDELW 546
           P+ V    G  R G + A     +Q+   GEVD+   V  +R  R      M +  ++  
Sbjct: 265 PIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDR----GGMIQTAEQYQ 320

Query: 547 FIEFGRGAALPTTPEETSP 565
           F+           PEE SP
Sbjct: 321 FLHHTLALYAGQLPEEPSP 339


>M33689-1|AAA60157.1|  435|Homo sapiens non-receptor tyrosine
           phosphatase 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>M31724-1|AAA60223.1|  435|Homo sapiens PTPN1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>BT006752-1|AAP35398.1|  435|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>BC018164-1|AAH18164.1|  435|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>BC015660-1|AAH15660.1|  435|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>AL133230-1|CAC00618.2|  435|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>AL034429-1|CAI23215.1|  435|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 1 protein.
          Length = 435

 Score =  118 bits (283), Expect = 2e-25
 Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 11/199 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           ++YI+TQGP  +T   FW M+W++++  +VML +  +   + C QYWP  +EK+  + D 
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 108 SVGI-VQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNA-LLEFXX 165
           ++ + +  E++ +++  T R  + E     E R IL FHYT W     P S A  L F  
Sbjct: 139 NLKLTLISEDIKSYY--TVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNF-- 194

Query: 166 XXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAE---EEDSFDVFGCLKK 222
                       +P  GP+VVHC+ G GRSG +   D  L L +   +  S D+   L +
Sbjct: 195 --LFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLE 252

Query: 223 LRESRKGLIENEEQYKFVY 241
           +R+ R GLI+  +Q +F Y
Sbjct: 253 MRKFRMGLIQTADQLRFSY 271



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 74/287 (25%), Positives = 122/287 (42%), Gaps = 27/287 (9%)

Query: 264 LKQKSQRDPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRP 323
           ++ + + + + K   +   YQ I  +   F    C       N+ +NR   V P D+ R 
Sbjct: 1   MEMEKEFEQIDKSGSWAAIYQDIRHEASDFP---CRVAKLPKNKNRNRYRDVSPFDHSRI 57

Query: 324 YLTSFQGNSFTDYINAVFVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVL-CV 382
            L   + N   DYINA  +      R YI T+ PL  T G FW +V++ +   VV+L  V
Sbjct: 58  KLHQ-EDN---DYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRV 113

Query: 383 PPKNSQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKK---IISLTELMA 439
             K S +   +WP+    +    +F          TN+K  +   + K    +   EL  
Sbjct: 114 MEKGSLKCAQYWPQKEEKEM---IF--------EDTNLKLTLISEDIKSYYTVRQLELEN 162

Query: 440 GVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE-LMNMVERWRQRTDYGPVCVVSPDGRSR 498
                T+ +  F  T WP    VP S  S +  L  + E      ++GPV V    G  R
Sbjct: 163 LTTQETREILHFHYTTWP-DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGR 221

Query: 499 AGVYCAANACIEQVIKH---GEVDVFQAVKTVRRHRPQLVENMCELK 542
           +G +C A+ C+  + K      VD+ + +  +R+ R  L++   +L+
Sbjct: 222 SGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLR 268


>Z79693-1|CAB01957.1|  670|Homo sapiens protein-tyrosine phosphatase
           NC-PTPCOM1 protein.
          Length = 670

 Score =  117 bits (282), Expect = 2e-25
 Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 23/224 (10%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 458 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 513

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 514 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 568

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 569 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 624

Query: 225 ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKS 268
             R G+++  EQY+FV+     H +C       S L QRL  +S
Sbjct: 625 MDRGGMVQTSEQYEFVH-----HALC----LYESRLQQRLSSES 659



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 441 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 500

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 501 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 545

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 546 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 604

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 605 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 632


>X82635-1|CAA57957.1|  382|Homo sapiens protein-tyrosine-phosphatase
           protein.
          Length = 382

 Score =  117 bits (282), Expect = 2e-25
 Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 23/224 (10%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 170 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 225

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 226 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 280

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 281 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 336

Query: 225 ESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKS 268
             R G+++  EQY+FV+     H +C       S L QRL  +S
Sbjct: 337 MDRGGMVQTSEQYEFVH-----HALC----LYESRLQQRLSSES 371



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 153 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 212

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 213 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 257

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 258 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 316

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 317 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 344


>U77917-1|AAB54007.1|  412|Homo sapiens Ch-1PTPase gamma minus form
           protein.
          Length = 412

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 213 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 268

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 269 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 323

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 324 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 379

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 380 MDRGGMVQTSEQYEFVHHAL 399



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 196 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 255

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 256 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 300

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 301 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 359

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 360 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 387


>U77916-1|AAB54006.1|  451|Homo sapiens Ch-1PTPase delta form
           protein.
          Length = 451

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 252 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 307

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 308 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 362

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 363 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 418

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 419 MDRGGMVQTSEQYEFVHHAL 438



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 235 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 294

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 295 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 339

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 340 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 398

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 399 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 426


>U42361-1|AAD09447.1|  657|Homo sapiens protein tyrosine phosphatase
           Cr1PTPase precursor protein.
          Length = 657

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 458 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 513

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 514 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 568

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 569 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 624

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 625 MDRGGMVQTSEQYEFVHHAL 644



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 441 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 500

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 501 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 545

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 546 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 604

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 605 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 632


>D64053-1|BAA10930.1|  657|Homo sapiens tyrosine phosphatase
           protein.
          Length = 657

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 458 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 513

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 514 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 568

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 569 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 624

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 625 MDRGGMVQTSEQYEFVHHAL 644



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 441 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 500

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 501 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 545

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 546 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 604

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 605 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 632


>BX571751-1|CAE11876.1|  412|Homo sapiens hypothetical protein
           protein.
          Length = 412

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 213 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 268

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 269 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 323

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 324 LDVEEGRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 379

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 380 MDRGGMVQTSEQYEFVHHAL 399



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 196 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 255

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 256 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 300

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 301 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEGRLASQGRGPVVVHCSAGIGRTGCFIATSIG 359

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 360 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 387


>BC122866-1|AAI22867.1|  412|Homo sapiens PTPRR protein protein.
          Length = 412

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 213 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 268

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 269 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 323

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 324 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 379

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 380 MDRGGMVQTSEQYEFVHHAL 399



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 196 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 255

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 256 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 300

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 301 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 359

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 360 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 387


>BC110900-1|AAI10901.1|  412|Homo sapiens PTPRR protein protein.
          Length = 412

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 213 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 268

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 269 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 323

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 324 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 379

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 380 MDRGGMVQTSEQYEFVHHAL 399



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 196 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 255

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 256 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 300

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 301 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 359

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 360 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 387


>AF263029-1|AAG47642.1|  657|Homo sapiens protein tyrosine
           phosphatase receptor type R protein.
          Length = 657

 Score =  117 bits (281), Expect = 3e-25
 Identities = 69/200 (34%), Positives = 101/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 458 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 513

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N+ IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 514 KVEVLVISVNECDNYTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 568

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 569 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 624

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 625 MDRGGMVQTSEQYEFVHHAL 644



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 441 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 500

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 501 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------YTIRNLVLKQGSHTQHVK 545

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 546 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 604

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 605 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 632


>BC119777-1|AAI19778.1|  412|Homo sapiens PTPRR protein protein.
          Length = 412

 Score =  115 bits (277), Expect = 8e-25
 Identities = 69/200 (34%), Positives = 100/200 (50%), Gaps = 14/200 (7%)

Query: 46  KPKAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYG 105
           K KA+I TQGP  +TV DFW+M+WQE +  IVM+TK  +  +  CV YWP   EK   YG
Sbjct: 213 KEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWP---EKRGIYG 268

Query: 106 DISVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFX 164
            + V ++   E  N  IR   L +         + +  + YT W  H  P S   LL+  
Sbjct: 269 KVEVLVISVNECDNHTIRNLVLKQGS-----HTQHVKHYWYTSWPDHKTPDSAQPLLQLM 323

Query: 165 XXXXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLR 224
                        +   GP+VVHC+ G GR+G ++A     +  +EE   D    + +LR
Sbjct: 324 LDVEEDRLA----SQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLR 379

Query: 225 ESRKGLIENEEQYKFVYDTL 244
             R G+++  EQY+FV+  L
Sbjct: 380 MDRGGMVQTSEQYEFVHHAL 399



 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 18/208 (8%)

Query: 331 NSFTDYINAVFVDGYT-KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQQ 389
           +S + YINA ++ GY+ K + +IAT+ P++ T  +FW +V+  +   +V++    + +++
Sbjct: 196 DSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEK 255

Query: 390 YPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQ 449
              +WPE R    YG V  +  +S N   N             ++  L+    + T+ V+
Sbjct: 256 CVLYWPEKRGI--YGKVEVL-VISVNECDN------------HTIRNLVLKQGSHTQHVK 300

Query: 450 LFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTD-YGPVCVVSPDGRSRAGVYCAANAC 508
            +  T WP  HK P S   L++LM  VE  R  +   GPV V    G  R G + A +  
Sbjct: 301 HYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIG 359

Query: 509 IEQVIKHGEVDVFQAVKTVRRHRPQLVE 536
            +Q+ + G VD    V  +R  R  +V+
Sbjct: 360 CQQLKEEGVVDALSIVCQLRMDRGGMVQ 387


>X62055-1|CAA43982.1|  597|Homo sapiens protein-tyrosine
           phosphatase 1C protein.
          Length = 597

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 321 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 379

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 380 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 437

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 438 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFI 518



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 184 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 242

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 243 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 300

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 301 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 359

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 360 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 409

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 410 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 468

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 469 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 508


>U47924-18|AAB51323.1|  595|Homo sapiens protein tyrosine
           phosphatase 1C protein.
          Length = 595

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>U47924-17|AAB51322.1|  556|Homo sapiens protein tyrosine
           phosphatase 1C protein.
          Length = 556

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 280 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 338

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 339 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 396

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 397 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 452

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 453 RAQRSGMVQTEAQYKFIYVAIAQFI 477



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 143 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 201

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 202 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 259

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 260 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 318

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 319 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 368

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 369 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 427

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 428 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 467


>U15528-2|AAA82880.1|  595|Homo sapiens protein tyrosine phosphatase
           1C protein.
          Length = 595

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>U15528-1|AAA82879.1|  556|Homo sapiens protein tyrosine phosphatase
           1C protein.
          Length = 556

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 280 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 338

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 339 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 396

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 397 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 452

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 453 RAQRSGMVQTEAQYKFIYVAIAQFI 477



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 143 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 201

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 202 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 259

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 260 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 318

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 319 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 368

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 369 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 427

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 428 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 467


>M77273-1|AAA36610.1|  595|Homo sapiens tyrosine phosphatase
           protein.
          Length = 595

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>M74903-1|AAA35963.1|  595|Homo sapiens hematopoietic cell
           phophatase protein.
          Length = 595

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>BT007390-1|AAP36054.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 321 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 379

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 380 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 437

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 438 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFI 518



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 184 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 242

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 243 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 300

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 301 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 359

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 360 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 409

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 410 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 468

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 469 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 508


>BC007667-1|AAH07667.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 321 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 379

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 380 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 437

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 438 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFI 518



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 184 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 242

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 243 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 300

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 301 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 359

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 360 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 409

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 410 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 468

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 469 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 508


>BC002523-1|AAH02523.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 321 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 379

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 380 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 437

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 438 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFI 518



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 184 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 242

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 243 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 300

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 301 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 359

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 360 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 409

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 410 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 468

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 469 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 508


>AF178946-1|AAD53317.1|  624|Homo sapiens 70 kDa SHP-1L protein
           protein.
          Length = 624

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>AB079851-2|BAC81775.1|  595|Homo sapiens protein tyrosine
           phosphatase SHP-1 protein.
          Length = 595

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFI 516



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>AB079851-1|BAC81774.1|  597|Homo sapiens protein tyrosine
           phosphatase SHP-1 protein.
          Length = 597

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/205 (31%), Positives = 98/205 (47%), Gaps = 11/205 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 321 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 379

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 380 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGVLSFLDQ 437

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 438 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493

Query: 224 RESRKGLIENEEQYKFVYDTLEEHV 248
           R  R G+++ E QYKF+Y  + + +
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFI 518



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 184 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 242

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 243 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 300

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 301 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 359

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 360 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 409

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 410 EIWHYQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 468

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 469 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 508


>AK223629-1|BAD97349.1|  595|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 isoform 1 variant
           protein.
          Length = 595

 Score =  113 bits (272), Expect = 3e-24
 Identities = 65/198 (32%), Positives = 95/198 (47%), Gaps = 11/198 (5%)

Query: 48  KAYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDI 107
           K YI +QG  E TV DFW+M WQE +  IVM T+  +  +  CV YW P       YG  
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW-PEVGMQRAYGPY 377

Query: 108 SVGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           SV    E +   + +RT ++   + G +I E  I  + Y  W  H  P     +L F   
Sbjct: 378 SVTNCGEHDTTEYKLRTLQVSPLDNGDLIRE--IWHYQYLSWPDHGVPSEPGGILSFLDQ 435

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAID---ANLELAEEEDSFDVFGCLKKL 223
                       P AGP++VHC+ G GR+G  + ID    N+     +   D+   ++ +
Sbjct: 436 INQRQESL----PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491

Query: 224 RESRKGLIENEEQYKFVY 241
           R  R G+++ E QYKF+Y
Sbjct: 492 RAQRSGMVQTEAQYKFIY 509



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 73/340 (21%), Positives = 145/340 (42%), Gaps = 27/340 (7%)

Query: 215 DVFGCLKKLRESRKGLIENEEQYKFVYDTLEEHVVCGISWFPVSELSQRLKQKSQRDPVT 274
           + F  L  L E  K     E    FVY   + +    ++   +      L +K + +   
Sbjct: 182 ETFDSLTDLVEHFKKTGIEEASGAFVY-LRQPYYATRVNAADIENRVLELNKKQESEDTA 240

Query: 275 KLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGN-SF 333
           K   + +E++ + KQ  +  +     G R +N+ KNR   ++P D+ R  L     N   
Sbjct: 241 KAG-FWEEFESLQKQEVK-NLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPG 298

Query: 334 TDYINAVFVDGYT-----KPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLCVPP--KN 386
           +DYINA ++           + YIA++  L  T  +FW + +  E + V+V+      K 
Sbjct: 299 SDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQ-ENSRVIVMTTREVEKG 357

Query: 387 SQQYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTK 446
             +  P+WPE    + YGP +++ +   +  T  K    +++   +   +L+       +
Sbjct: 358 RNKCVPYWPEVGMQRAYGP-YSVTNCGEHDTTEYKLRTLQVSP--LDNGDLI-------R 407

Query: 447 TVQLFQLTCWPMGHKVPSSTNSLVELMNMVERWRQRTDY-GPVCVVSPDGRSRAGVYCAA 505
            +  +Q   WP  H VPS    ++  ++ + + ++   + GP+ V    G  R G     
Sbjct: 408 EIWHYQYLSWP-DHGVPSEPGGILSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVI 466

Query: 506 NACIEQVIKHG---EVDVFQAVKTVRRHRPQLVENMCELK 542
           +  +E +   G   ++D+ + ++ VR  R  +V+   + K
Sbjct: 467 DMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYK 506


>X62899-1|CAA44688.2|  591|Homo sapiens Islet Cell Antigen 512
           protein.
          Length = 591

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 391 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 448

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 449 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 502

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 503 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 559

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 560 QRPGLVRSKDQFEFALTAVAEEV 582



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 313 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 370

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 371 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 430

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 431 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 479

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 480 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 536

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 537 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 591


>L18983-1|AAA90974.1|  979|Homo sapiens tyrosine phosphatase
           protein.
          Length = 979

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 779 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 836

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 837 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 890

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 891 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 947

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 948 QRPGLVRSKDQFEFALTAVAEEV 970



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 701 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 758

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 759 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 818

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 819 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 867

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 868 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 924

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 925 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 979


>BT006975-1|AAP35621.1|  591|Homo sapiens protein tyrosine
           phosphatase, receptor type, N protein.
          Length = 591

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 391 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 448

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 449 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 502

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 503 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 559

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 560 QRPGLVRSKDQFEFALTAVAEEV 582



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 313 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 370

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 371 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 430

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 431 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 479

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 480 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 536

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 537 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 591


>BC070053-1|AAH70053.1|  950|Homo sapiens PTPRN protein protein.
          Length = 950

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 750 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 807

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 808 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 861

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 862 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 918

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 919 QRPGLVRSKDQFEFALTAVAEEV 941



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 672 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 729

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 730 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 789

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 790 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 838

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 839 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 895

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 896 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 950


>BC007713-1|AAH07713.2|  811|Homo sapiens PTPRN protein protein.
          Length = 811

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 611 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 668

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 669 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 722

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 723 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 779

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 780 QRPGLVRSKDQFEFALTAVAEEV 802



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 533 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 590

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 591 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 650

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 651 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 699

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 700 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 756

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 757 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 811


>AC114803-2|AAY24038.1|  979|Homo sapiens unknown protein.
          Length = 979

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/203 (32%), Positives = 100/203 (49%), Gaps = 14/203 (6%)

Query: 49  AYIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDIS 108
           AYI TQGP   T+ DFW+M+W+     IVMLT   +     C +YWP   E    Y    
Sbjct: 779 AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWP--DEGASLYHVYE 836

Query: 109 VGIVQEE-ELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXX 166
           V +V E     +F +R+F L   +     E R + QFH+  W +   P S   LL+F   
Sbjct: 837 VNLVSEHIWCEDFLVRSFYLKNVQ---TQETRTLTQFHFLSWPAEGTPASTRPLLDF--- 890

Query: 167 XXXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANL-ELAEEEDSFDVFGCLKKLRE 225
                         + P++VHC+DG GR+G Y+ ID  L  +A+     D+   L+ +R+
Sbjct: 891 ---RRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRD 947

Query: 226 SRKGLIENEEQYKFVYDTLEEHV 248
            R GL+ +++Q++F    + E V
Sbjct: 948 QRPGLVRSKDQFEFALTAVAEEV 970



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 75/295 (25%), Positives = 126/295 (42%), Gaps = 20/295 (6%)

Query: 271 DPVTKLNEYQKEYQQICKQTPRFTIGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQG 330
           D +   +   KE+Q +C          CA      N +KNR    +P D+ R  L     
Sbjct: 701 DHLRNRDRLAKEWQALCAYQAE--PNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESS 758

Query: 331 NSFTDYINAV-FVDGYTKPREYIATEWPLMMTQGEFWSLVYDYECAAVVVLC-VPPKNSQ 388
            S +DYINA   ++   +   YIAT+ PL  T  +FW +V++  C  +V+L  +     +
Sbjct: 759 PSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVK 818

Query: 389 QYPPFWPEGRHSKKYGPVFTIDHVSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTV 448
           Q   +WP+   S  +  V+ ++ VS +       W      +   L  +       T+T+
Sbjct: 819 QCDRYWPDEGASLYH--VYEVNLVSEH------IWCEDFLVRSFYLKNVQT---QETRTL 867

Query: 449 QLFQLTCWPMGHKVPSSTNSLVELMNMVER-WRQRTDYGPVCVVSPDGRSRAGVYCAANA 507
             F    WP     P+ST  L++    V + +R R+   P+ V   DG  R G Y   + 
Sbjct: 868 TQFHFLSWP-AEGTPASTRPLLDFRRKVNKCYRGRS--CPIIVHCSDGAGRTGTYILIDM 924

Query: 508 CIEQVIKH-GEVDVFQAVKTVRRHRPQLVENMCELKDELWFIEFGRGAALPTTPE 561
            + ++ K   E+D+   ++ VR  RP LV +  + +  L  +     A L   P+
Sbjct: 925 VLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ 979


>AL050040-1|CAB43248.1|  398|Homo sapiens hypothetical protein
           protein.
          Length = 398

 Score =  110 bits (264), Expect = 3e-23
 Identities = 59/197 (29%), Positives = 95/197 (48%), Gaps = 10/197 (5%)

Query: 50  YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGDISV 109
           YI TQGP   T+ DFW+M+ +  +  I M+T+  +   + C  YWP + +K        V
Sbjct: 203 YIATQGPLLSTIDDFWQMVLENNSNVIAMITREMEGGIIKCYHYWPISLKKPLELKHFRV 262

Query: 110 GIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFSNALLEFXXXXXX 169
            +   + L  F IR F++ +   G       + Q  +T+W  H  P S            
Sbjct: 263 FLENYQILQYFIIRMFQVVEKSTGT---SHSVKQLQFTKWPDHGTPAS-------ADSFI 312

Query: 170 XXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESRKG 229
                   +   GPMVVHC+ G GR+GV+L +D       ++ SF++   + ++RE R G
Sbjct: 313 KYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKDCSFNIMDIVAQMREQRSG 372

Query: 230 LIENEEQYKFVYDTLEE 246
           +++ +EQY F YD + E
Sbjct: 373 MVQTKEQYHFCYDIVLE 389



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 62/244 (25%), Positives = 106/244 (43%), Gaps = 22/244 (9%)

Query: 296 GDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPREY--IA 353
           G+   G++  NREKNR   ++P D+ R  L    G S  DYINA ++       EY  IA
Sbjct: 151 GEFYSGNQPSNREKNRYRDILPYDSTRVPL----GKS-KDYINASYIRIVNCGEEYFYIA 205

Query: 354 TEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNS-QQYPPFWPEGRHSKKYGPVFTIDHV 412
           T+ PL+ T  +FW +V +     + ++    +    +   +WP    S K         V
Sbjct: 206 TQGPLLSTIDDFWQMVLENNSNVIAMITREMEGGIIKCYHYWP---ISLKKPLELKHFRV 262

Query: 413 SHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVEL 472
              +Y  ++ +I R    +  + E   G    + +V+  Q T WP  H  P+S +S ++ 
Sbjct: 263 FLENYQILQYFIIR----MFQVVEKSTGT---SHSVKQLQFTKWP-DHGTPASADSFIKY 314

Query: 473 MNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHRP 532
           +      R+    GP+ V    G  R GV+   +     ++K    ++   V  +R  R 
Sbjct: 315 IRYA---RKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIVKDCSFNIMDIVAQMREQRS 371

Query: 533 QLVE 536
            +V+
Sbjct: 372 GMVQ 375


>X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphatase
            protein.
          Length = 2466

 Score =  109 bits (262), Expect = 6e-23
 Identities = 61/197 (30%), Positives = 98/197 (49%), Gaps = 13/197 (6%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD-IS 108
            YI  QGP   TV DFW+MIW++++  I M+T+  +  K+ C +YWP    K     + + 
Sbjct: 2260 YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLR 2319

Query: 109  VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXXX 167
            + +V+ ++L  F +R   L   E     E R I   ++T W  H  P   + LL F    
Sbjct: 2320 LALVRMQQLKGFVVRAMTL---EDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2376

Query: 168  XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                         +GP++ HC+ G GRSG  + ID  L L  ++  FD+   ++ +R  R
Sbjct: 2377 RHIH--------RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQR 2428

Query: 228  KGLIENEEQYKFVYDTL 244
             G+++ E+QY F Y  +
Sbjct: 2429 HGMVQTEDQYIFCYQVI 2445



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 52/245 (21%), Positives = 98/245 (40%), Gaps = 21/245 (8%)

Query: 295  IGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPRE--YI 352
            +  C  G   +NR KNR   ++P D  R  L    G     YINA F+       E  YI
Sbjct: 2207 LDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYI 2261

Query: 353  ATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDH 411
            A + PL  T G+FW ++++ +   + ++    +  + +   +WP      K   V     
Sbjct: 2262 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWP--NILGKTTMVSNRLR 2319

Query: 412  VSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE 471
            ++      +K ++ R     ++L ++        + +     T WP  H  PS  +   +
Sbjct: 2320 LALVRMQQLKGFVVR----AMTLEDIQT---REVRHISHLNFTAWP-DHDTPSQPD---D 2368

Query: 472  LMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHR 531
            L+  +   R     GP+      G  R+G     +  +  + +  + D+   V+ +R  R
Sbjct: 2369 LLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQR 2428

Query: 532  PQLVE 536
              +V+
Sbjct: 2429 HGMVQ 2433


>X79676-1|CAA56124.1| 1267|Homo sapiens tyrosine phosphatase protein.
          Length = 1267

 Score =  109 bits (262), Expect = 6e-23
 Identities = 61/197 (30%), Positives = 98/197 (49%), Gaps = 13/197 (6%)

Query: 50   YIVTQGPTEDTVVDFWRMIWQERAAAIVMLTKTFDFIKVMCVQYWPPNKEKDETYGD-IS 108
            YI  QGP   TV DFW+MIW++++  I M+T+  +  K+ C +YWP    K     + + 
Sbjct: 1061 YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLR 1120

Query: 109  VGIVQEEELANFFIRTFRLYKTEKGVVIEERFILQFHYTQWHSHTCPFS-NALLEFXXXX 167
            + +V+ ++L  F +R   L   E     E R I   ++T W  H  P   + LL F    
Sbjct: 1121 LALVRMQQLKGFVVRAMTL---EDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 1177

Query: 168  XXXXXXXXXXNPAAGPMVVHCNDGGGRSGVYLAIDANLELAEEEDSFDVFGCLKKLRESR 227
                         +GP++ HC+ G GRSG  + ID  L L  ++  FD+   ++ +R  R
Sbjct: 1178 RHIH--------RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQR 1229

Query: 228  KGLIENEEQYKFVYDTL 244
             G+++ E+QY F Y  +
Sbjct: 1230 HGMVQTEDQYIFCYQVI 1246



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 52/245 (21%), Positives = 98/245 (40%), Gaps = 21/245 (8%)

Query: 295  IGDCAGGHRGDNREKNRDVLVVPPDNFRPYLTSFQGNSFTDYINAVFVDGYTKPRE--YI 352
            +  C  G   +NR KNR   ++P D  R  L    G     YINA F+       E  YI
Sbjct: 1008 LDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYI 1062

Query: 353  ATEWPLMMTQGEFWSLVYDYECAAVVVLCVPPKNSQ-QYPPFWPEGRHSKKYGPVFTIDH 411
            A + PL  T G+FW ++++ +   + ++    +  + +   +WP      K   V     
Sbjct: 1063 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWP--NILGKTTMVSNRLR 1120

Query: 412  VSHNHYTNIKTWIFRINKKIISLTELMAGVKAPTKTVQLFQLTCWPMGHKVPSSTNSLVE 471
            ++      +K ++ R     ++L ++        + +     T WP  H  PS  +   +
Sbjct: 1121 LALVRMQQLKGFVVR----AMTLEDIQT---REVRHISHLNFTAWP-DHDTPSQPD---D 1169

Query: 472  LMNMVERWRQRTDYGPVCVVSPDGRSRAGVYCAANACIEQVIKHGEVDVFQAVKTVRRHR 531
            L+  +   R     GP+      G  R+G     +  +  + +  + D+   V+ +R  R
Sbjct: 1170 LLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQR 1229

Query: 532  PQLVE 536
              +V+
Sbjct: 1230 HGMVQ 1234


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.317    0.132    0.403 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 164,890,192
Number of Sequences: 224733
Number of extensions: 7324751
Number of successful extensions: 21126
Number of sequences better than 10.0: 380
Number of HSP's better than 10.0 without gapping: 327
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 18323
Number of HSP's gapped (non-prelim): 1150
length of query: 1140
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1042
effective length of database: 51,211,004
effective search space: 53361866168
effective search space used: 53361866168
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)