Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001949-TA|BGIBMGA001949-PA|IPR001547|Glycoside
hydrolase, family 5, IPR011028|Cyclin-like,
IPR002720|Retinoblastoma-associated protein, A-box
(723 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L14812-1|AAA02489.1| 1068|Homo sapiens p107 protein. 442 e-123
BC032247-1|AAH32247.1| 1014|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL391114-2|CAI95152.1| 1014|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL391114-1|CAI95151.1| 1068|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL365505-2|CAI95178.1| 1014|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL365505-1|CAI95177.1| 1068|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL136172-4|CAI95717.1| 1014|Homo sapiens retinoblastoma-like 1 (... 442 e-123
AL136172-3|CAI95716.1| 1068|Homo sapiens retinoblastoma-like 1 (... 442 e-123
X76061-1|CAA53661.1| 1139|Homo sapiens 130K protein protein. 404 e-112
X74594-1|CAA52671.1| 1082|Homo sapiens Rb2/p130 protein protein. 404 e-112
S67171-1|AAB29227.1| 1139|Homo sapiens p130 protein. 404 e-112
BC034490-1|AAH34490.1| 1139|Homo sapiens retinoblastoma-like 2 (... 404 e-112
M74547-1|AAA36397.1| 935|Homo sapiens p107 protein. 336 2e-91
BX537767-1|CAD97830.1| 849|Homo sapiens hypothetical protein pr... 164 9e-40
AF551763-1|AAN64133.1| 928|Homo sapiens retinoblastoma 1 (inclu... 109 3e-23
M33647-1|AAA69806.1| 928|Homo sapiens RB1 protein. 107 2e-22
M28419-1|AAA69808.1| 928|Homo sapiens MIC2 protein. 107 2e-22
M27866-1|AAA53484.1| 928|Homo sapiens retinoblastoma susceptibi... 107 2e-22
M15400-1|AAA69807.1| 928|Homo sapiens RB1 protein. 107 2e-22
L41870-1|AAB59465.1| 928|Homo sapiens retinoblastoma suspectibi... 107 2e-22
L11910-1|AAA53483.1| 928|Homo sapiens retinoblastoma susceptibi... 107 2e-22
BC040540-1|AAH40540.1| 928|Homo sapiens retinoblastoma 1 (inclu... 107 2e-22
BC039060-1|AAH39060.1| 928|Homo sapiens retinoblastoma 1 (inclu... 107 2e-22
AL392048-1|CAH72243.1| 928|Homo sapiens retinoblastoma 1 (inclu... 107 2e-22
AL136960-1|CAH70901.1| 928|Homo sapiens retinoblastoma 1 (inclu... 107 2e-22
AB208788-1|BAD92025.1| 960|Homo sapiens Retinoblastoma-associat... 107 2e-22
L49221-1|AAA82560.1| 59|Homo sapiens retinoblastoma suspectibi... 46 5e-04
L41904-1|AAB59580.1| 55|Homo sapiens RB1 protein. 41 0.018
L41924-1|AAB59479.1| 51|Homo sapiens RB1 protein. 40 0.041
CR456521-1|CAG30407.1| 485|Homo sapiens MIL1 protein. 34 1.5
BC007658-1|AAH07658.1| 485|Homo sapiens BCL2-like 13 (apoptosis... 34 1.5
AF325209-1|AAK27358.1| 485|Homo sapiens Bcl-Rambo protein. 34 1.5
AF246665-1|AAK15150.1| 201|Homo sapiens MIL1 protein isoform 1 ... 34 1.5
AF247457-1|AAF68025.2| 2058|Homo sapiens myosin X protein. 33 3.6
AF234532-1|AAF37875.1| 2058|Homo sapiens myosin X protein. 33 3.6
AF184153-1|AAF17363.1| 149|Homo sapiens myosin X protein. 33 3.6
AF132021-1|AAF36524.1| 1540|Homo sapiens myosin X protein. 33 3.6
AB018342-1|BAA34519.2| 2111|Homo sapiens KIAA0799 protein protein. 33 3.6
AF009040-1|AAC51922.1| 1575|Homo sapiens synaptojanin protein. 32 6.2
AF009039-1|AAC51921.1| 1311|Homo sapiens synaptojanin protein. 32 6.2
AB020717-1|BAA74933.2| 1315|Homo sapiens KIAA0910 protein protein. 32 6.2
>L14812-1|AAA02489.1| 1068|Homo sapiens p107 protein.
Length = 1068
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 60.1 bits (139), Expect = 3e-08
Identities = 34/98 (34%), Positives = 57/98 (58%), Gaps = 8/98 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ER DLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERSDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
+Y+ P + L Y+F+ SP+K L+ IN+++
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMI 1021
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>BC032247-1|AAH32247.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAK 666
+Y+ P + L Y+F+ SP+K
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSK 1012
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL391114-2|CAI95152.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAK 666
+Y+ P + L Y+F+ SP+K
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSK 1012
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL391114-1|CAI95151.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 62.5 bits (145), Expect = 5e-09
Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 8/98 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
+Y+ P + L Y+F+ SP+K L+ IN+++
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMI 1021
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL365505-2|CAI95178.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAK 666
+Y+ P + L Y+F+ SP+K
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSK 1012
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL365505-1|CAI95177.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 62.5 bits (145), Expect = 5e-09
Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 8/98 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
+Y+ P + L Y+F+ SP+K L+ IN+++
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMI 1021
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL136172-4|CAI95717.1| 1014|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1014
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/89 (35%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAK 666
+Y+ P + L Y+F+ SP+K
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSK 1012
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>AL136172-3|CAI95716.1| 1068|Homo sapiens retinoblastoma-like 1
(p107) protein.
Length = 1068
Score = 442 bits (1088), Expect = e-123
Identities = 232/560 (41%), Positives = 334/560 (59%), Gaps = 25/560 (4%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G+ HW+AC+LYVACR S+ PTV G ++EGNCVSLT++LR LSLIQFF K+K WM+M
Sbjct: 53 GEVTHWLACSLYVACRKSIIPTVGKG-IMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDM 111
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
+++ +F+ERI RLE F VS+V+F+K++PIF+++F EP K R+ + PCS
Sbjct: 112 SNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVK 171
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLP 179
LF F W L++ KG F +DLV+ YH+LL CLD IFANA M R D++NP F GLP
Sbjct: 172 DLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLP 231
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
+D+ DF + PPC+I+ LCE+ DGL EA +KE+ +KP I F++ ILKG
Sbjct: 232 SDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC--- 288
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVI 298
+LDL F N K++N YE YVL+VG+FDERIFLG A E+IG K + D + ++
Sbjct: 289 --LLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLT 346
Query: 299 A----------NFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
A +F P TPLTGRRYL + +TPV+ A S
Sbjct: 347 AQANVEYNLQQHFEKKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKN 406
Query: 349 QPSPTLLRLFTECGVTDEMIN-AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVT 407
PS L+ +F C V + + N K++K Q + H + R +
Sbjct: 407 APSDQLINIFESC-VRNPVENIMKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAE 465
Query: 408 CLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQ 467
LYYK+ E ++ +E R+ + + +LL Q+ + ++ ACC EIVL AY + FP +++
Sbjct: 466 ILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIE 524
Query: 468 IFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKT 525
+ L F+FYK+IE+V+++ + LSRD++KHLN++EE++LESL W+ DS LW+ Q+S
Sbjct: 525 VLNLQPFYFYKVIEVVIRS-EEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSAN 583
Query: 526 PVPASADVSVQDSPFRRTNG 545
VP +V + + F NG
Sbjct: 584 KVPTCEEV-IFPNNFETGNG 602
Score = 62.5 bits (145), Expect = 5e-09
Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 8/98 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ERGDLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 926 ERGDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 983
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
+Y+ P + L Y+F+ SP+K L+ IN+++
Sbjct: 984 SIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMI 1021
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 620 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 667
>X76061-1|CAA53661.1| 1139|Homo sapiens 130K protein protein.
Length = 1139
Score = 404 bits (994), Expect = e-112
Identities = 239/637 (37%), Positives = 342/637 (53%), Gaps = 46/637 (7%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G++LHW+ACALYVACR SV PTV G VEGN VSLT++L+ SLI+FF K+K W +M
Sbjct: 81 GNDLHWLACALYVACRKSV-PTVSKG-TVEGNYVSLTRILKCSEQSLIEFFNKMKKWEDM 138
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
A++ F+ER RLE F VS+V+F+K++PIF ++F E +Q R+ + QPC+ +
Sbjct: 139 ANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTVS 198
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFM-ARRVDIINPEFTGLP 179
+F F W L+I KG F ++DLV+ YH+LL LD ++ NA + R +++NP F GL
Sbjct: 199 EIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLS 258
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
D+ D K PPC+I LC + DGL EA +KE+ WKP I +EK +LKG E
Sbjct: 259 EDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLYEKKLLKGKEENL 318
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIG----MKNKVSGDEIS 295
G L+ G F + K++N YE YVLSVG DERIFLGE A E+IG N SG E +
Sbjct: 319 TGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETA 378
Query: 296 EVI-------ANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
E + +F S TPLTG RY+ S +TPVS A +S
Sbjct: 379 ERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVSTATHSLSRLHTMLTGLRN 438
Query: 349 QPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTC 408
PS L ++ C A +K Q ++ N E S
Sbjct: 439 APSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCA-KEIASKHFRFAEM 497
Query: 409 LYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQI 468
LYYKV E +I++E ++ + L +L Q+ + ++ ACC E+V +Y FP + +I
Sbjct: 498 LYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPG-NFPFITEI 556
Query: 469 FKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWDQL--SKTP 526
F + +HFYK+IE+ ++A D L R+V+KHLN +EE++L+ L W +SPLW+++ ++
Sbjct: 557 FDVPLYHFYKVIEVFIRA-EDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENR 615
Query: 527 VPA------------SADVSVQDSPF--RR-------TNGL----QSPVSTIDRFMSPMA 561
VP + ++ + SP RR T GL SP + DR+ SP A
Sbjct: 616 VPTCEEVMPPQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPA 675
Query: 562 EQAKKQLFKDPIKPGQSLLGSPERGDLINFYNKVYVQ 598
+++LF + P G+P R N V VQ
Sbjct: 676 STTRRRLFVENDSPSDG--GTPGRMPPQPLVNAVPVQ 710
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDECSLSPLPTGRCEARSPAGTRVSERHQLYV 643
ERGDLI FYN +Y++ ++ FA+++S + D LSP P R SP ++S+ H +Y+
Sbjct: 1001 ERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR--TGSPRRIQLSQNHPVYI 1058
Query: 644 KPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
P + + Y FS SP+K L+ INS++
Sbjct: 1059 SPHKNETMLSPREKIFYYFSNSPSKRLREINSMI 1092
>X74594-1|CAA52671.1| 1082|Homo sapiens Rb2/p130 protein protein.
Length = 1082
Score = 404 bits (994), Expect = e-112
Identities = 239/637 (37%), Positives = 342/637 (53%), Gaps = 46/637 (7%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G++LHW+ACALYVACR SV PTV G VEGN VSLT++L+ SLI+FF K+K W +M
Sbjct: 24 GNDLHWLACALYVACRKSV-PTVSKG-TVEGNYVSLTRILKCSEQSLIEFFNKMKKWEDM 81
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
A++ F+ER RLE F VS+V+F+K++PIF ++F E +Q R+ + QPC+ +
Sbjct: 82 ANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTVS 141
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFM-ARRVDIINPEFTGLP 179
+F F W L+I KG F ++DLV+ YH+LL LD ++ NA + R +++NP F GL
Sbjct: 142 EIFHFCWMLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLS 201
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
D+ D K PPC+I LC + DGL EA +KE+ WKP I +EK +LKG E
Sbjct: 202 EDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLYEKKLLKGKEENL 261
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIG----MKNKVSGDEIS 295
G L+ G F + K++N YE YVLSVG DERIFLGE A E+IG N SG E +
Sbjct: 262 TGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETA 321
Query: 296 EVI-------ANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
E + +F S TPLTG RY+ S +TPVS A +S
Sbjct: 322 ERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVSTATHSLSRLHTMLTGLRN 381
Query: 349 QPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTC 408
PS L ++ C A +K Q ++ N E S
Sbjct: 382 APSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCA-KEIASKHFRFAEM 440
Query: 409 LYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQI 468
LYYKV E +I++E ++ + L +L Q+ + ++ ACC E+V +Y FP + +I
Sbjct: 441 LYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPG-NFPFITEI 499
Query: 469 FKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWDQL--SKTP 526
F + +HFYK+IE+ ++A D L R+V+KHLN +EE++L+ L W +SPLW+++ ++
Sbjct: 500 FDVPLYHFYKVIEVFIRA-EDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENR 558
Query: 527 VPA------------SADVSVQDSPF--RR-------TNGL----QSPVSTIDRFMSPMA 561
VP + ++ + SP RR T GL SP + DR+ SP A
Sbjct: 559 VPTCEEVMPPQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPA 618
Query: 562 EQAKKQLFKDPIKPGQSLLGSPERGDLINFYNKVYVQ 598
+++LF + P G+P R N V VQ
Sbjct: 619 STTRRRLFVENDSPSDG--GTPGRMPPQPLVNAVPVQ 653
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDECSLSPLPTGRCEARSPAGTRVSERHQLYV 643
ERGDLI FYN +Y++ ++ FA+++S + D LSP P R SP ++S+ H +Y+
Sbjct: 944 ERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR--TGSPRRIQLSQNHPVYI 1001
Query: 644 KPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
P + + Y FS SP+K L+ INS++
Sbjct: 1002 SPHKNETMLSPREKIFYYFSNSPSKRLREINSMI 1035
>S67171-1|AAB29227.1| 1139|Homo sapiens p130 protein.
Length = 1139
Score = 404 bits (994), Expect = e-112
Identities = 239/637 (37%), Positives = 342/637 (53%), Gaps = 46/637 (7%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G++LHW+ACALYVACR SV PTV G VEGN VSLT++L+ SLI+FF K+K W +M
Sbjct: 81 GNDLHWLACALYVACRKSV-PTVSKG-TVEGNYVSLTRILKCSEQSLIEFFNKMKKWEDM 138
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
A++ F+ER RLE F VS+V+F+K++PIF ++F E +Q R+ + QPC+ +
Sbjct: 139 ANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTVS 198
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFM-ARRVDIINPEFTGLP 179
+F F W L+I KG F ++DLV+ YH+LL LD ++ NA + R +++NP F GL
Sbjct: 199 EIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLS 258
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
D+ D K PPC+I LC + DGL EA +KE+ WKP I +EK +LKG E
Sbjct: 259 EDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLYEKKLLKGKEENL 318
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIG----MKNKVSGDEIS 295
G L+ G F + K++N YE YVLSVG DERIFLGE A E+IG N SG E +
Sbjct: 319 TGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETA 378
Query: 296 EVI-------ANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
E + +F S TPLTG RY+ S +TPVS A +S
Sbjct: 379 ERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVSTATHSLSRLHTMLTGLRN 438
Query: 349 QPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTC 408
PS L ++ C A +K Q ++ N E S
Sbjct: 439 APSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCA-KEIASKHFRFAEM 497
Query: 409 LYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQI 468
LYYKV E +I++E ++ + L +L Q+ + ++ ACC E+V +Y FP + +I
Sbjct: 498 LYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPG-NFPFITEI 556
Query: 469 FKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWDQL--SKTP 526
F + +HFYK+IE+ ++A D L R+V+KHLN +EE++L+ L W +SPLW+++ ++
Sbjct: 557 FDVPLYHFYKVIEVFIRA-EDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENR 615
Query: 527 VPA------------SADVSVQDSPF--RR-------TNGL----QSPVSTIDRFMSPMA 561
VP + ++ + SP RR T GL SP + DR+ SP A
Sbjct: 616 VPTCEEVMPPQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPA 675
Query: 562 EQAKKQLFKDPIKPGQSLLGSPERGDLINFYNKVYVQ 598
+++LF + P G+P R N V VQ
Sbjct: 676 STTRRRLFVENDSPSDG--GTPGRMPPQPLVNAVPVQ 710
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDECSLSPLPTGRCEARSPAGTRVSERHQLYV 643
ERGDLI FYN +Y++ ++ FA+++S + D LSP P R SP ++S+ H +Y+
Sbjct: 1001 ERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR--TGSPRRIQLSQNHPVYI 1058
Query: 644 KPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
P + + Y FS SP+K L+ INS++
Sbjct: 1059 SPHKNETMLSPREKIFYYFSNSPSKRLREINSMI 1092
>BC034490-1|AAH34490.1| 1139|Homo sapiens retinoblastoma-like 2
(p130) protein.
Length = 1139
Score = 404 bits (994), Expect = e-112
Identities = 239/637 (37%), Positives = 342/637 (53%), Gaps = 46/637 (7%)
Query: 1 GDELHWMACALYVACRTSVTPTVQTGKVVEGNCVSLTKLLRLCNLSLIQFFIKIKNWMEM 60
G++LHW+ACALYVACR SV PTV G VEGN VSLT++L+ SLI+FF K+K W +M
Sbjct: 81 GNDLHWLACALYVACRKSV-PTVSKG-TVEGNYVSLTRILKCSEQSLIEFFNKMKKWEDM 138
Query: 61 ASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTN 120
A++ F+ER RLE F VS+V+F+K++PIF ++F E +Q R+ + QPC+ +
Sbjct: 139 ANLPPHFRERTERLERNFTVSAVIFKKYEPIFQDIFKYPQEEQPRQQRGRKQRRQPCTVS 198
Query: 121 ALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFM-ARRVDIINPEFTGLP 179
+F F W L+I KG F ++DLV+ YH+LL LD ++ NA + R +++NP F GL
Sbjct: 199 EIFHFCWVLFIYAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCSNRKELVNPNFKGLS 258
Query: 180 TDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPT 239
D+ D K PPC+I LC + DGL EA +KE+ WKP I +EK +LKG E
Sbjct: 259 EDFHAKDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKPYIRKLYEKKLLKGKEENL 318
Query: 240 LGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIG----MKNKVSGDEIS 295
G L+ G F + K++N YE YVLSVG DERIFLGE A E+IG N SG E +
Sbjct: 319 TGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETA 378
Query: 296 EVI-------ANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXP 348
E + +F S TPLTG RY+ S +TPVS A +S
Sbjct: 379 ERVQMKNILQQHFDKSKALRISTPLTGVRYIKENSPCVTPVSTATHSLSRLHTMLTGLRN 438
Query: 349 QPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTC 408
PS L ++ C A +K Q ++ N E S
Sbjct: 439 APSEKLEQILRTCSRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCA-KEIASKHFRFAEM 497
Query: 409 LYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQI 468
LYYKV E +I++E ++ + L +L Q+ + ++ ACC E+V +Y FP + +I
Sbjct: 498 LYYKVLESVIEQEQKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPG-NFPFITEI 556
Query: 469 FKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWDQL--SKTP 526
F + +HFYK+IE+ ++A D L R+V+KHLN +EE++L+ L W +SPLW+++ ++
Sbjct: 557 FDVPLYHFYKVIEVFIRA-EDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENR 615
Query: 527 VPA------------SADVSVQDSPF--RR-------TNGL----QSPVSTIDRFMSPMA 561
VP + ++ + SP RR T GL SP + DR+ SP A
Sbjct: 616 VPTCEEVMPPQNLERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPA 675
Query: 562 EQAKKQLFKDPIKPGQSLLGSPERGDLINFYNKVYVQ 598
+++LF + P G+P R N V VQ
Sbjct: 676 STTRRRLFVENDSPSDG--GTPGRMPPQPLVNAVPVQ 710
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDECSLSPLPTGRCEARSPAGTRVSERHQLYV 643
ERGDLI FYN +Y++ ++ FA+++S + D LSP P R SP ++S+ H +Y+
Sbjct: 1001 ERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR--TGSPRRIQLSQNHPVYI 1058
Query: 644 KPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
P + + Y FS SP+K L+ INS++
Sbjct: 1059 SPHKNETMLSPREKIFYYFSNSPSKRLREINSMI 1092
>M74547-1|AAA36397.1| 935|Homo sapiens p107 protein.
Length = 935
Score = 336 bits (825), Expect = 2e-91
Identities = 184/478 (38%), Positives = 270/478 (56%), Gaps = 24/478 (5%)
Query: 83 VLFRKFQPIFMELFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSAN 142
V+F+K++PIF+++F EP K R+ + PCS LF F W L++ KG F +
Sbjct: 1 VIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGD 60
Query: 143 DLVDMYHILLSCLDYIFANAFMA-RRVDIINPEFTGLPTDWTKNDFKMPKTPPCVISTLC 201
DLV+ YH+LL CLD IFANA M R D++NP F GLP+D+ DF + PPC+I+ LC
Sbjct: 61 DLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLC 120
Query: 202 EIKDGLSKEATTMKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYET 261
E+ DGL EA +KE+ +KP I F++ ILKG +LDL F N K++N YE
Sbjct: 121 ELHDGLLVEAKGIKEHYFKPYISKLFDRKILKGEC-----LLDLSSFTDNSKAVNKEYEE 175
Query: 262 YVLSVGEFDERIFLGEQANEQIGMKNKVSGD-EISEVIA----------NFGPSGRACPD 310
YVL+VG+FDERIFLG A E+IG K + D + ++ A +F P
Sbjct: 176 YVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFEKKRSFAPS 235
Query: 311 TPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMIN- 369
TPLTGRRYL + +TPV+ A S PS L+ +F C V + + N
Sbjct: 236 TPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESC-VRNPVENI 294
Query: 370 AKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVS 429
K++K Q + H + R + LYYK+ E ++ +E R+ +
Sbjct: 295 MKILKGIGETFCQHYTQSTDEQPGSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMD 354
Query: 430 LQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQAVVD 489
+ +LL Q+ + ++ ACC EIVL AY + FP ++++ L F+FYK+IE+V+++ +
Sbjct: 355 MSVLLEQDIFHRSLMACCLEIVLFAYS-SPRTFPWIIEVLNLQPFYFYKVIEVVIRS-EE 412
Query: 490 KLSRDVIKHLNAVEEEVLESLVWTSDSPLWD--QLSKTPVPASADVSVQDSPFRRTNG 545
LSRD++KHLN++EE++LESL W+ DS LW+ Q+S VP +V + + F NG
Sbjct: 413 GLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEV-IFPNNFETGNG 469
Score = 60.1 bits (139), Expect = 3e-08
Identities = 34/98 (34%), Positives = 57/98 (58%), Gaps = 8/98 (8%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDEC----SLSPLPTGRCEARSPAGTRVSERH 639
ER DLI FYN +YV +++FAL++ ++D LSP P + + SP R+S++H
Sbjct: 793 ERSDLIKFYNTIYVGRVKSFALKYDLANQDHMMDAPPLSPFPHIKQQPGSP--RRISQQH 850
Query: 640 QLYVKPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
+Y+ P + L Y+F+ SP+K L+ IN+++
Sbjct: 851 SIYISPHKNGSGLTPRSALLYKFNGSPSKSLKDINNMI 888
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 528 PASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKKQLF-KDPIK 574
P +V RR SP+S +R+ SP A AK++LF +DP K
Sbjct: 487 PRVKEVRTDSGSLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPK 534
>BX537767-1|CAD97830.1| 849|Homo sapiens hypothetical protein
protein.
Length = 849
Score = 164 bits (399), Expect = 9e-40
Identities = 123/384 (32%), Positives = 181/384 (47%), Gaps = 43/384 (11%)
Query: 253 KSLNNLYETYVLSVGEFDERIFLGEQANEQIG----MKNKVSGDEISEVI-------ANF 301
K++N YE YVLSVG DERIFLGE A E+IG N SG E +E + +F
Sbjct: 42 KAINKAYEEYVLSVGNLDERIFLGEDAEEEIGTLSRCLNAGSGTETAERVQMKNILQQHF 101
Query: 302 GPSGRACPDTPLTGRRYLSRRSEELTPVSEAKNSXXXXXXXXXXXXPQPSPTLLRLFTEC 361
S TPLTG RY+ S +TPV A +S PS L ++ C
Sbjct: 102 DKSKALRISTPLTGVRYIKENSPCVTPVPTATHSLSRLHTMLTGLRNAPSEKLEQILRTC 161
Query: 362 GVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEE 421
A +K Q ++ N E S LYYKV E +I++E
Sbjct: 162 SRDPTQAIANRLKEMFEIYSQHFQPDEDFSNCA-KEIASKHFRFAEMLYYKVLESVIEQE 220
Query: 422 HRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNSFKFPRVLQIFKLSAFHFYKIIE 481
++ + L +L Q+ + ++ ACC E+V +Y FP + +IF + +HFYK+IE
Sbjct: 221 QKRLGDMDLSGILEQDAFHRSLLACCLEVVTFSYKPPG-NFPFITEIFDVPLYHFYKVIE 279
Query: 482 LVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDSPLWDQL--SKTPVPA---------- 529
+ ++A D L R+V+KHLN +EE++L+ L W +SPLW+++ ++ VP
Sbjct: 280 VFIRA-EDGLCREVVKHLNQIEEQILDHLAWKPESPLWEKIRDNENRVPTCEEVMPPQNL 338
Query: 530 --SADVSVQDSPF--RR-------TNGL----QSPVSTIDRFMSPMAEQAKKQLFKDPIK 574
+ ++ + SP RR T GL SP + DR+ SP A +++LF +
Sbjct: 339 ERADEICIAGSPLTPRRVTEVRADTGGLGRSITSPTTLYDRYSSPPASTTRRRLFVENDS 398
Query: 575 PGQSLLGSPERGDLINFYNKVYVQ 598
P G+P R N V VQ
Sbjct: 399 PSDG--GTPGRMPPQPLVNAVPVQ 420
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 4/94 (4%)
Query: 584 ERGDLINFYNKVYVQCMQNFALRFSGRHRDECSLSPLPTGRCEARSPAGTRVSERHQLYV 643
ERGDLI FYN +Y++ ++ FA+++S + D LSP P R SP ++S+ H +Y+
Sbjct: 711 ERGDLIQFYNNIYIKQIKTFAMKYSQANMDAPPLSPYPFVR--TGSPRRIQLSQNHPVYI 768
Query: 644 KPLTDPP--PQHHHLTYRFSRSPAKDLQAINSLV 675
P + + Y FS SP+K L+ INS++
Sbjct: 769 SPHKNETMLSPREKIFYYFSNSPSKRLREINSMI 802
>AF551763-1|AAN64133.1| 928|Homo sapiens retinoblastoma 1
(including osteosarcoma) protein.
Length = 928
Score = 109 bits (262), Expect = 3e-23
Identities = 127/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y N+ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSSNTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>M33647-1|AAA69806.1| 928|Homo sapiens RB1 protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>M28419-1|AAA69808.1| 928|Homo sapiens MIC2 protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>M27866-1|AAA53484.1| 928|Homo sapiens retinoblastoma
susceptibility protein protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>M15400-1|AAA69807.1| 928|Homo sapiens RB1 protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 127/530 (23%), Positives = 217/530 (40%), Gaps = 59/530 (11%)
Query: 53 KIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFMELFVGLTNEPVKQVSKRRP 112
K N ++ ST +SRL K+ V LF K + +++ +P +S
Sbjct: 130 KFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYL---TQPSSSISTE-- 184
Query: 113 KLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSCLDYIFANAFMARRVDIIN 172
++ + + +W ++ KGE +DLV + ++L LDY ++ + +
Sbjct: 185 ----INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIK---LSPPMLLKE 237
Query: 173 PEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATTMKEYSWKPVIDSFFEKGI 231
P T +P + + + + I+ E + + E + V + +F+ I
Sbjct: 238 PYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFI 297
Query: 232 LKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFLGEQANEQIGMKNKVSG 291
NS LG++ +++L+ YE L + D R+FL Q
Sbjct: 298 PFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDRRLFLDHDKTLQ--------- 344
Query: 292 DEISEVIANFGPSGRACPDTPLTGRRYLSRRSEEL------TPVSEAKNSXXXXXXXXXX 345
++ I +F +T T R+ S EE+ TPV N+
Sbjct: 345 ---TDSIDSF--------ETQRTPRK--SNLDEEVNIIPPHTPVRTVMNTIQQLMMILNS 391
Query: 346 XXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNTPHSETISIRCNM 405
QPS L+ F C V + K +K G++ F +A E S R +
Sbjct: 392 ASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQGCVEIGSQRYKL 448
Query: 406 VTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLHAYGVNS------ 459
LYY+V E ++K E + + LL+ + +++ AC E+V+ Y ++
Sbjct: 449 GVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTSQNLDS 508
Query: 460 ---FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTSDS 516
FP +L + L AF FYK+IE ++A L+R++IKHL E ++ESL W SDS
Sbjct: 509 GTDLSFPWILNVLNLKAFDFYKVIESFIKAE-GNLTREMIKHLERCEHRIMESLAWLSDS 567
Query: 517 PLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQAKK 566
PL+D L K +S LQ+ + D ++SP+ KK
Sbjct: 568 PLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPKKK 616
>L41870-1|AAB59465.1| 928|Homo sapiens retinoblastoma
suspectibility protein protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>L11910-1|AAA53483.1| 928|Homo sapiens retinoblastoma
susceptibility protein protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>BC040540-1|AAH40540.1| 928|Homo sapiens retinoblastoma 1
(including osteosarcoma) protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>BC039060-1|AAH39060.1| 928|Homo sapiens retinoblastoma 1
(including osteosarcoma) protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>AL392048-1|CAH72243.1| 928|Homo sapiens retinoblastoma 1
(including osteosarcoma) protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>AL136960-1|CAH70901.1| 928|Homo sapiens retinoblastoma 1
(including osteosarcoma) protein.
Length = 928
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 116 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 171
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 172 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 222
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 223 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 279
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 280 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 335
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 336 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 379
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 380 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 436
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 437 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 496
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 497 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 555
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 556 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 614
Query: 565 KK 566
KK
Sbjct: 615 KK 616
>AB208788-1|BAD92025.1| 960|Homo sapiens Retinoblastoma-associated
protein variant protein.
Length = 960
Score = 107 bits (256), Expect = 2e-22
Identities = 126/542 (23%), Positives = 218/542 (40%), Gaps = 51/542 (9%)
Query: 35 SLTKLLRLCNLSLIQFFIKIKNWMEMASMSTDFKERISRLEHKFAVSSVLFRKFQPIFME 94
+ T+L + +S+ +FF N ++ ST +SRL K+ V LF K +
Sbjct: 148 TFTELQKNIEISVHKFF----NLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCEL 203
Query: 95 LFVGLTNEPVKQVSKRRPKLQPCSTNALFEFTWCLYICVKGEFHNSANDLVDMYHILLSC 154
+++ +P +S ++ + + +W ++ KGE +DLV + ++L
Sbjct: 204 IYL---TQPSSSISTE------INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCV 254
Query: 155 LDYIFANAFMARRVDIINPEFTG-LPTDWTKNDFKMPKTPPCVISTLCEIKDGLSKEATT 213
LDY ++ + + P T +P + + + + I+ E + +
Sbjct: 255 LDYFIK---LSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCK 311
Query: 214 MKEYSWKPVIDSFFEKGILKGNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERI 273
E + V + +F+ I NS LG++ +++L+ YE L + D R+
Sbjct: 312 EHECNIDEVKNVYFKNFIPFMNS---LGLVTSNGLP-EVENLSKRYEEIYLKNKDLDARL 367
Query: 274 FLGEQANEQIGMKNKVSGDEISEVIANFGPSGRACPDTPLTGRRYLSRRSEELTPVSEAK 333
FL Q + +N P P T PV
Sbjct: 368 FLDHDKTLQTDSIDSFETQRTPRK-SNLDEEVNVIP--PHT-------------PVRTVM 411
Query: 334 NSXXXXXXXXXXXXPQPSPTLLRLFTECGVTDEMINAKLIKPCNGWMEQFGASLKEAHNT 393
N+ QPS L+ F C V + K +K G++ F +A
Sbjct: 412 NTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDI-GYI--FKEKFAKAVGQ 468
Query: 394 PHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQLTVYACCTEIVLH 453
E S R + LYY+V E ++K E + + LL+ + +++ AC E+V+
Sbjct: 469 GCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMA 528
Query: 454 AYGVNS---------FKFPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEE 504
Y ++ FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 529 TYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCEH 587
Query: 505 EVLESLVWTSDSPLWDQLSKTPVPASADVSVQDSPFRRTNGLQSPVSTIDRFMSPMAEQA 564
++ESL W SDSPL+D L K +S LQ+ + D ++SP+
Sbjct: 588 RIMESLAWLSDSPLFD-LIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPK 646
Query: 565 KK 566
KK
Sbjct: 647 KK 648
>L49221-1|AAA82560.1| 59|Homo sapiens retinoblastoma
suspectibility protein protein.
Length = 59
Score = 46.0 bits (104), Expect = 5e-04
Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 7/53 (13%)
Query: 462 FPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVEEEVLESLVWTS 514
FP +L + L AF FYK+IE ++A ++IKHL E ++ESL W S
Sbjct: 14 FPWILNVLNLKAFDFYKVIESFIKA-------EMIKHLERCEHRIMESLAWLS 59
>L41904-1|AAB59580.1| 55|Homo sapiens RB1 protein.
Length = 55
Score = 40.7 bits (91), Expect = 0.018
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 462 FPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHLNAVE 503
FP +L + L AF FYK+IE ++A L+R++IKHL E
Sbjct: 14 FPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHLERCE 54
>L41924-1|AAB59479.1| 51|Homo sapiens RB1 protein.
Length = 51
Score = 39.5 bits (88), Expect = 0.041
Identities = 18/38 (47%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Query: 462 FPRVLQIFKLSAFHFYKIIELVVQAVVDKLSRDVIKHL 499
FP +L + L AF FYK+IE ++A L+R++IKHL
Sbjct: 14 FPWILNVLNLKAFDFYKVIESFIKA-EGNLTREMIKHL 50
>CR456521-1|CAG30407.1| 485|Homo sapiens MIL1 protein.
Length = 485
Score = 34.3 bits (75), Expect = 1.5
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 381 EQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQ 440
E F ++ + H +P + +M CL + + +E ++ +LQMLLSQ
Sbjct: 76 EAFTSTGFDRHTSPVFSPANPESSMEDCLAH--LGEKVSQELKEPLHKALQMLLSQPVTY 133
Query: 441 LTVYACCTEIVLHAYGVNSFKFPRVL 466
C E +HA G N P VL
Sbjct: 134 QAFRECTLETTVHASGWNKILVPLVL 159
>BC007658-1|AAH07658.1| 485|Homo sapiens BCL2-like 13 (apoptosis
facilitator) protein.
Length = 485
Score = 34.3 bits (75), Expect = 1.5
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 381 EQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQ 440
E F ++ + H +P + +M CL + + +E ++ +LQMLLSQ
Sbjct: 76 EAFTSTGFDRHTSPVFSPANPESSMEDCLAH--LGEKVSQELKEPLHKALQMLLSQPVTY 133
Query: 441 LTVYACCTEIVLHAYGVNSFKFPRVL 466
C E +HA G N P VL
Sbjct: 134 QAFRECTLETTVHASGWNKILVPLVL 159
>AF325209-1|AAK27358.1| 485|Homo sapiens Bcl-Rambo protein.
Length = 485
Score = 34.3 bits (75), Expect = 1.5
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 381 EQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQ 440
E F ++ + H +P + +M CL + + +E ++ +LQMLLSQ
Sbjct: 76 EAFTSTGFDRHTSPVFSPANPESSMEDCLAH--LGEKVSQELKEPLHKALQMLLSQPVTY 133
Query: 441 LTVYACCTEIVLHAYGVNSFKFPRVL 466
C E +HA G N P VL
Sbjct: 134 QAFRECTLETTVHASGWNKILVPLVL 159
>AF246665-1|AAK15150.1| 201|Homo sapiens MIL1 protein isoform 1
protein.
Length = 201
Score = 34.3 bits (75), Expect = 1.5
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 381 EQFGASLKEAHNTPHSETISIRCNMVTCLYYKVFEHIIKEEHRKKPQVSLQMLLSQETYQ 440
E F ++ + H +P + +M CL + + +E ++ +LQMLLSQ
Sbjct: 76 EAFTSTGFDRHTSPVFSPANPESSMEDCLAH--LGEKVSQELKEPLHKALQMLLSQPVTY 133
Query: 441 LTVYACCTEIVLHAYGVNSFKFPRVL 466
C E +HA G N P VL
Sbjct: 134 QAFRECTLETTVHASGWNKILVPLVL 159
>AF247457-1|AAF68025.2| 2058|Homo sapiens myosin X protein.
Length = 2058
Score = 33.1 bits (72), Expect = 3.6
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 431 QMLLSQETYQLTVYACCTEIVL-----HAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQ 485
Q + S+++ + +YACC E V+ G FK +L IF F + +
Sbjct: 393 QAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN 452
Query: 486 AVVDKLSRDVIKHLNAVE--EEVLESLVW 512
+KL KH+ ++E E E LVW
Sbjct: 453 YANEKLQEYFNKHIFSLEQLEYSREGLVW 481
>AF234532-1|AAF37875.1| 2058|Homo sapiens myosin X protein.
Length = 2058
Score = 33.1 bits (72), Expect = 3.6
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 431 QMLLSQETYQLTVYACCTEIVL-----HAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQ 485
Q + S+++ + +YACC E V+ G FK +L IF F + +
Sbjct: 393 QAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN 452
Query: 486 AVVDKLSRDVIKHLNAVE--EEVLESLVW 512
+KL KH+ ++E E E LVW
Sbjct: 453 YANEKLQEYFNKHIFSLEQLEYSREGLVW 481
>AF184153-1|AAF17363.1| 149|Homo sapiens myosin X protein.
Length = 149
Score = 33.1 bits (72), Expect = 3.6
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 431 QMLLSQETYQLTVYACCTEIVL-----HAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQ 485
Q + S+++ + +YACC E V+ G FK +L IF F + +
Sbjct: 47 QAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN 106
Query: 486 AVVDKLSRDVIKHLNAVE--EEVLESLVW 512
+KL KH+ ++E E E LVW
Sbjct: 107 YANEKLQEYFNKHIFSLEQLEYSREGLVW 135
>AF132021-1|AAF36524.1| 1540|Homo sapiens myosin X protein.
Length = 1540
Score = 33.1 bits (72), Expect = 3.6
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 431 QMLLSQETYQLTVYACCTEIVL-----HAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQ 485
Q + S+++ + +YACC E V+ G FK +L IF F + +
Sbjct: 393 QAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN 452
Query: 486 AVVDKLSRDVIKHLNAVE--EEVLESLVW 512
+KL KH+ ++E E E LVW
Sbjct: 453 YANEKLQEYFNKHIFSLEQLEYSREGLVW 481
>AB018342-1|BAA34519.2| 2111|Homo sapiens KIAA0799 protein protein.
Length = 2111
Score = 33.1 bits (72), Expect = 3.6
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 431 QMLLSQETYQLTVYACCTEIVL-----HAYGVNSFKFPRVLQIFKLSAFHFYKIIELVVQ 485
Q + S+++ + +YACC E V+ G FK +L IF F + +
Sbjct: 446 QAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN 505
Query: 486 AVVDKLSRDVIKHLNAVE--EEVLESLVW 512
+KL KH+ ++E E E LVW
Sbjct: 506 YANEKLQEYFNKHIFSLEQLEYSREGLVW 534
>AF009040-1|AAC51922.1| 1575|Homo sapiens synaptojanin protein.
Length = 1575
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/88 (20%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 217 YSWKPVIDSFFEKGILK-GNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFL 275
Y+W P + + LK + P + ++D+ +F+V + N+Y+ + G D + +
Sbjct: 839 YTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLV 898
Query: 276 GEQAN-EQIGMKNKVSGDEISEVIANFG 302
+++ + + DE+ + A+FG
Sbjct: 899 SIKSSLPENNFFDDALIDELLQQFASFG 926
>AF009039-1|AAC51921.1| 1311|Homo sapiens synaptojanin protein.
Length = 1311
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/88 (20%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 217 YSWKPVIDSFFEKGILK-GNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFL 275
Y+W P + + LK + P + ++D+ +F+V + N+Y+ + G D + +
Sbjct: 839 YTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLV 898
Query: 276 GEQAN-EQIGMKNKVSGDEISEVIANFG 302
+++ + + DE+ + A+FG
Sbjct: 899 SIKSSLPENNFFDDALIDELLQQFASFG 926
>AB020717-1|BAA74933.2| 1315|Homo sapiens KIAA0910 protein protein.
Length = 1315
Score = 32.3 bits (70), Expect = 6.2
Identities = 18/88 (20%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 217 YSWKPVIDSFFEKGILK-GNSEPTLGILDLGVFDVNLKSLNNLYETYVLSVGEFDERIFL 275
Y+W P + + LK + P + ++D+ +F+V + N+Y+ + G D + +
Sbjct: 875 YTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLV 934
Query: 276 GEQAN-EQIGMKNKVSGDEISEVIANFG 302
+++ + + DE+ + A+FG
Sbjct: 935 SIKSSLPENNFFDDALIDELLQQFASFG 962
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,303,666
Number of Sequences: 224733
Number of extensions: 4656428
Number of successful extensions: 9059
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 8840
Number of HSP's gapped (non-prelim): 82
length of query: 723
length of database: 73,234,838
effective HSP length: 95
effective length of query: 628
effective length of database: 51,885,203
effective search space: 32583907484
effective search space used: 32583907484
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 69 (31.9 bits)
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