Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001924-TA|BGIBMGA001924-PA|IPR003961|Fibronectin, type
III, IPR013098|Immunoglobulin I-set, IPR008957|Fibronectin, type
III-like fold, IPR003962|Fibronectin, type III subdomain,
IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2,
IPR007110|Immunoglobulin-like
(1104 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 449 e-125
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 449 e-125
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 449 e-125
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 449 e-125
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 445 e-124
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 432 e-120
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 432 e-120
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 432 e-120
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 432 e-120
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 432 e-120
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 369 e-101
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 198 9e-50
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 198 9e-50
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 181 1e-44
BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein. 173 2e-42
AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein pr... 173 3e-42
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 165 1e-39
AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein. 163 2e-39
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 163 3e-39
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 163 3e-39
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 163 4e-39
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 162 5e-39
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 160 2e-38
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 160 3e-38
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 155 6e-37
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 155 8e-37
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 151 1e-35
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 150 2e-35
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 150 2e-35
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 150 2e-35
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 150 2e-35
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 150 2e-35
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 150 2e-35
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 148 9e-35
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 148 9e-35
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 148 9e-35
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 147 2e-34
X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphat... 146 3e-34
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 146 3e-34
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 146 3e-34
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 146 4e-34
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 145 9e-34
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 144 1e-33
AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine phosph... 144 1e-33
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 144 2e-33
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 143 3e-33
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 143 3e-33
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 143 3e-33
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 142 6e-33
AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]... 142 8e-33
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 141 1e-32
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 141 1e-32
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 141 1e-32
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 141 1e-32
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 141 1e-32
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 140 3e-32
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 140 3e-32
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 138 8e-32
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 138 8e-32
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 137 2e-31
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 137 2e-31
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 137 2e-31
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 137 2e-31
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 135 9e-31
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 135 9e-31
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 135 9e-31
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 135 9e-31
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 132 9e-30
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 129 5e-29
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 129 6e-29
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 129 6e-29
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 129 6e-29
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 122 9e-27
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 122 9e-27
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 122 9e-27
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 121 1e-26
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 121 1e-26
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 118 9e-26
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 118 9e-26
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 118 9e-26
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 109 5e-23
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 107 2e-22
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 107 2e-22
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 106 5e-22
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 105 9e-22
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 103 5e-21
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 103 5e-21
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 103 5e-21
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 103 5e-21
AK074077-1|BAB84903.1| 572|Homo sapiens FLJ00148 protein protein. 102 8e-21
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 101 2e-20
AK001694-1|BAA91841.1| 574|Homo sapiens protein ( Homo sapiens ... 101 2e-20
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 101 2e-20
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 101 2e-20
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 100 3e-20
U42594-1|AAD00019.1| 782|Homo sapiens fibronectin protein. 94 3e-18
BX640638-1|CAE45786.1| 1034|Homo sapiens hypothetical protein pr... 94 3e-18
BC117176-1|AAI17177.1| 2176|Homo sapiens fibronectin 1 protein. 94 3e-18
BC025843-1|AAH25843.1| 449|Homo sapiens L1CAM protein protein. 94 3e-18
AL832202-1|CAD91166.1| 2265|Homo sapiens hypothetical protein pr... 94 3e-18
AB209840-1|BAD93077.1| 2351|Homo sapiens Fibronectin 1 variant p... 94 3e-18
AB191261-1|BAD52437.1| 2265|Homo sapiens fibronectin 1 protein. 94 3e-18
AB209287-1|BAD92524.1| 1011|Homo sapiens Fibronectin 1 variant p... 93 7e-18
BC070072-1|AAH70072.1| 853|Homo sapiens FNDC3A protein protein. 91 2e-17
BC060816-1|AAH60816.1| 853|Homo sapiens FNDC3A protein protein. 91 2e-17
BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein pr... 91 3e-17
BC132812-1|AAI32813.1| 1198|Homo sapiens FNDC3A protein protein. 91 3e-17
AL137000-1|CAI39726.2| 1142|Homo sapiens fibronectin type III do... 91 3e-17
AJ749707-1|CAG44603.1| 1134|Homo sapiens human gene expressed in... 91 3e-17
AJ749706-1|CAG44602.1| 1198|Homo sapiens human gene expressed in... 91 3e-17
AB023187-1|BAA76814.2| 1151|Homo sapiens KIAA0970 protein protein. 91 3e-17
BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa prot... 90 4e-17
X02761-1|CAA26536.1| 2328|Homo sapiens fibronectin precursor pro... 90 5e-17
BX640999-1|CAE46002.1| 2193|Homo sapiens hypothetical protein pr... 90 5e-17
BX640920-1|CAE45958.1| 1255|Homo sapiens hypothetical protein pr... 90 5e-17
BX537590-1|CAD97791.1| 2446|Homo sapiens hypothetical protein pr... 90 5e-17
AC012462-1|AAX76513.1| 2217|Homo sapiens unknown protein. 90 5e-17
X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein. 89 6e-17
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 89 6e-17
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 89 6e-17
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 89 6e-17
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 89 8e-17
BX640731-1|CAE45847.1| 2444|Homo sapiens hypothetical protein pr... 89 1e-16
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 88 2e-16
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 88 2e-16
BX538018-1|CAD97965.1| 2444|Homo sapiens hypothetical protein pr... 87 2e-16
BX538017-1|CAD97964.1| 2444|Homo sapiens hypothetical protein pr... 87 2e-16
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 87 4e-16
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 84 3e-15
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 83 4e-15
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 83 4e-15
AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isofo... 83 4e-15
AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 83 4e-15
AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 83 4e-15
AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (auto... 83 4e-15
AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (auto... 83 4e-15
AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (auto... 83 4e-15
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 83 7e-15
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 83 7e-15
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 82 1e-14
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 82 1e-14
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 82 1e-14
AL354664-1|CAH71310.1| 3063|Homo sapiens collagen type XII alpha... 81 2e-14
AL096771-3|CAI19908.1| 3063|Homo sapiens collagen type XII alpha... 81 2e-14
AL080250-2|CAI19898.1| 3063|Homo sapiens collagen type XII alpha... 81 2e-14
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 81 3e-14
AY358146-1|AAQ88513.1| 847|Homo sapiens YVTM2421 protein. 80 4e-14
AK223599-1|BAD97319.1| 1204|Homo sapiens factor for adipocyte di... 80 5e-14
AB098597-1|BAC53727.1| 1204|Homo sapiens FAD104 protein. 80 5e-14
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 79 9e-14
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 79 9e-14
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 79 9e-14
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 79 9e-14
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 79 9e-14
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 79 9e-14
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 79 9e-14
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 79 9e-14
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 79 9e-14
BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein. 78 2e-13
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 78 2e-13
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 78 2e-13
BC039297-1|AAH39297.1| 1204|Homo sapiens fibronectin type III do... 77 3e-13
U42593-1|AAD00018.1| 545|Homo sapiens fibronectin protein. 76 6e-13
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 76 6e-13
AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens ... 75 1e-12
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 75 2e-12
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 74 2e-12
L02870-1|AAA75438.1| 2944|Homo sapiens alpha-1 type VII collagen... 74 3e-12
U73778-1|AAC51244.1| 3063|Homo sapiens collagen type XII alpha-1... 73 6e-12
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 73 6e-12
L23982-1|AAA58965.1| 2912|Homo sapiens collagen type VII protein. 73 8e-12
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 71 2e-11
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 71 2e-11
AF091889-1|AAF75819.1| 1546|Homo sapiens Usher syndrome type IIa... 71 2e-11
AF055580-1|AAC23748.2| 1546|Homo sapiens Usher syndrome type IIa... 71 2e-11
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 71 2e-11
L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin bi... 71 2e-11
BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein ... 71 2e-11
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 71 2e-11
AL445650-3|CAH70620.1| 1546|Homo sapiens Usher syndrome 2A (auto... 71 2e-11
AL358858-1|CAH71587.1| 1546|Homo sapiens Usher syndrome 2A (auto... 71 2e-11
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 71 3e-11
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,... 71 3e-11
X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein. 70 5e-11
X53587-1|CAA37656.1| 1822|Homo sapiens integrin beta 4 protein p... 70 5e-11
X52186-1|CAA36433.1| 1805|Homo sapiens integrin beta 4 subunit p... 70 5e-11
X51841-1|CAA36134.1| 1752|Homo sapiens protein ( Human mRNA for ... 70 5e-11
U66541-3|AAC51632.1| 1752|Homo sapiens beta4-integrin protein. 70 5e-11
U66541-2|AAC51634.1| 1805|Homo sapiens beta4-integrin protein. 70 5e-11
U66541-1|AAC51633.1| 1822|Homo sapiens beta4-integrin protein. 70 5e-11
U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H ... 70 5e-11
BC126411-1|AAI26412.1| 1752|Homo sapiens integrin, beta 4 protein. 70 5e-11
BC118916-1|AAI18917.1| 1752|Homo sapiens ITGB4 protein protein. 70 5e-11
AJ251004-1|CAB61345.1| 1873|Homo sapiens integrin beta 4 protein. 70 5e-11
AB208913-1|BAD92150.1| 1515|Homo sapiens integrin beta 4 isoform... 70 5e-11
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 69 9e-11
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 69 9e-11
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 69 1e-10
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 68 2e-10
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 68 2e-10
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 68 2e-10
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 67 3e-10
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 67 3e-10
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 67 3e-10
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 67 3e-10
AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein. 66 9e-10
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 65 1e-09
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 65 1e-09
AL391822-9|CAI14665.1| 297|Homo sapiens neurofascin homolog (ch... 64 3e-09
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 64 3e-09
M10905-1|AAA52462.1| 793|Homo sapiens FN1 protein. 64 3e-09
U42458-1|AAD09450.1| 287|Homo sapiens fibronectin protein. 63 5e-09
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 63 5e-09
AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens ... 63 5e-09
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 63 5e-09
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 62 8e-09
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 62 8e-09
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 62 1e-08
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 62 1e-08
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 62 1e-08
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 62 1e-08
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 62 1e-08
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 62 1e-08
AK129856-1|BAC85243.1| 295|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 62 1e-08
AB209396-1|BAD92633.1| 675|Homo sapiens surface glycoprotein, I... 62 1e-08
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 62 1e-08
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 61 2e-08
AK075220-1|BAC11480.1| 760|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AF464063-1|AAN86141.1| 282|Homo sapiens contactin 4a protein. 61 2e-08
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 61 2e-08
AY358367-1|AAQ88733.1| 625|Homo sapiens YVTM2421 protein. 61 2e-08
AK096474-1|BAC04800.1| 403|Homo sapiens protein ( Homo sapiens ... 61 2e-08
BC033635-1|AAH33635.1| 753|Homo sapiens FNDC3B protein protein. 60 3e-08
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 60 3e-08
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 60 3e-08
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 60 3e-08
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 60 3e-08
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 60 6e-08
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 60 6e-08
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 60 6e-08
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 60 6e-08
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 60 6e-08
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 59 8e-08
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 59 8e-08
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 59 8e-08
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 59 8e-08
U64198-1|AAB36675.1| 862|Homo sapiens Il-12 receptor beta2 prot... 59 1e-07
AY640177-1|AAT45456.1| 862|Homo sapiens interleukin 12 receptor... 59 1e-07
AL389925-3|CAH70407.1| 862|Homo sapiens interleukin 12 receptor... 59 1e-07
AL358512-1|CAH69960.1| 862|Homo sapiens interleukin 12 receptor... 59 1e-07
AC104651-1|AAX93144.1| 432|Homo sapiens unknown protein. 59 1e-07
D13694-1|BAA02853.1| 1080|Homo sapiens type VII collagen protein. 58 1e-07
BC104774-1|AAI04775.1| 862|Homo sapiens interleukin 12 receptor... 58 1e-07
BC104772-1|AAI04773.1| 862|Homo sapiens interleukin 12 receptor... 58 1e-07
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 58 1e-07
AB102060-1|BAC80619.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102059-1|BAC80618.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102058-1|BAC80617.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102057-1|BAC80616.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102056-1|BAC80615.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102055-1|BAC80614.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102054-1|BAC80613.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102053-1|BAC80612.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102052-1|BAC80611.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102051-1|BAC80610.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102050-1|BAC80609.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102049-1|BAC80608.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102048-1|BAC80607.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102047-1|BAC80606.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102046-1|BAC80605.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102045-1|BAC80604.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102044-1|BAC80603.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102043-1|BAC80602.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102042-1|BAC80601.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
AB102041-1|BAC80600.1| 93|Homo sapiens L1 cell adhesion molecu... 58 1e-07
S51236-1|AAB24637.1| 887|Homo sapiens collagen VII protein. 58 2e-07
M96984-1|AAA36357.1| 884|Homo sapiens type VII collagen protein. 58 2e-07
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 58 2e-07
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 58 2e-07
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 57 3e-07
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 57 3e-07
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 57 3e-07
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 57 3e-07
BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein ... 57 3e-07
BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein ... 57 3e-07
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 57 3e-07
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 57 3e-07
AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein... 57 3e-07
AL096771-1|CAM28080.1| 637|Homo sapiens collagen type XII alpha... 57 3e-07
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 57 3e-07
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 57 4e-07
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 57 4e-07
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 57 4e-07
AK074556-1|BAC11057.1| 789|Homo sapiens protein ( Homo sapiens ... 57 4e-07
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 56 5e-07
Z93942-7|CAI19871.1| 1440|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-6|CAI19870.1| 1431|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-5|CAI19869.1| 1451|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-4|CAI19865.1| 1463|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-3|CAI19868.1| 1450|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-2|CAI19867.1| 1444|Homo sapiens protein tyrosine phosphat... 56 7e-07
Z93942-1|CAI19866.1| 1441|Homo sapiens protein tyrosine phosphat... 56 7e-07
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 56 7e-07
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 56 7e-07
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 56 7e-07
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 56 7e-07
AL136461-7|CAH72559.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-6|CAH72558.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-5|CAH72557.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-4|CAH72553.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-3|CAH72556.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-2|CAH72555.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL136461-1|CAH72554.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-7|CAI23316.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-6|CAI23315.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-5|CAI23314.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-4|CAI23310.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-3|CAI23313.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-2|CAI23312.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL121763-1|CAI23311.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-8|CAI19250.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-7|CAI19256.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-6|CAI19255.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-5|CAI19254.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-4|CAI19253.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-3|CAI19252.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL049812-2|CAI19251.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-7|CAI22915.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-6|CAI22914.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-5|CAI22913.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-4|CAI22909.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-3|CAI22912.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-2|CAI22911.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL035459-1|CAI22910.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-7|CAI19876.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-6|CAI19882.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-5|CAI19881.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-4|CAI19877.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-3|CAI19880.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-2|CAI19879.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL031656-1|CAI19878.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-7|CAI22495.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-6|CAI22494.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-5|CAI22493.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-4|CAI22489.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-3|CAI22492.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-2|CAI22491.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL024473-1|CAI22490.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-7|CAI20443.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-6|CAI20442.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-5|CAI20441.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-4|CAI20437.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-3|CAI20440.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-2|CAI20439.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL022239-1|CAI20438.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-7|CAI19987.1| 1440|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-6|CAI19986.1| 1431|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-5|CAI19985.1| 1451|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-4|CAI19981.1| 1463|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-3|CAI19984.1| 1450|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-2|CAI19983.1| 1444|Homo sapiens protein tyrosine phosph... 56 7e-07
AL021395-1|CAI19982.1| 1441|Homo sapiens protein tyrosine phosph... 56 7e-07
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 56 7e-07
AF043644-1|AAD09421.2| 1463|Homo sapiens receptor protein tyrosi... 56 7e-07
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 56 7e-07
AB006621-1|BAA22952.2| 1471|Homo sapiens KIAA0283 protein. 56 7e-07
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 56 9e-07
BC025310-1|AAH25310.1| 542|Homo sapiens LRFN1 protein protein. 56 9e-07
BC014678-1|AAH14678.1| 450|Homo sapiens LRFN1 protein protein. 56 9e-07
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 56 9e-07
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 56 9e-07
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 56 9e-07
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 56 9e-07
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 56 9e-07
BC043183-1|AAH43183.1| 1284|Homo sapiens collagen, type XX, alph... 55 2e-06
AL121827-18|CAI95066.1| 1297|Homo sapiens novel protein containi... 55 2e-06
AL121827-17|CAI95065.1| 1284|Homo sapiens novel protein containi... 55 2e-06
AB040943-1|BAA96034.1| 1140|Homo sapiens KIAA1510 protein protein. 54 2e-06
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 54 3e-06
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 54 3e-06
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 54 3e-06
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 54 3e-06
AK125972-1|BAC86370.1| 365|Homo sapiens protein ( Homo sapiens ... 54 3e-06
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 54 3e-06
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 54 3e-06
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 54 4e-06
BX649182-1|CAE46200.1| 1103|Homo sapiens hypothetical protein pr... 53 5e-06
BX640802-1|CAE45885.1| 1103|Homo sapiens hypothetical protein pr... 53 5e-06
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 53 5e-06
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 53 5e-06
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 53 5e-06
X61615-1|CAA43805.1| 1097|Homo sapiens leukemia inhibitory facto... 53 7e-06
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 53 7e-06
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 52 9e-06
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 52 9e-06
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 52 9e-06
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 52 1e-05
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 52 1e-05
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 52 1e-05
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 52 1e-05
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 52 1e-05
X97198-1|CAA65832.1| 1430|Homo sapiens receptor phosphatase PCP-... 52 2e-05
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 52 2e-05
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 52 2e-05
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 52 2e-05
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 52 2e-05
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 52 2e-05
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 52 2e-05
D83492-1|BAA21560.1| 1006|Homo sapiens Eph-family protein protein. 51 2e-05
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 51 2e-05
BC110607-1|AAI10608.2| 1006|Homo sapiens EPH receptor B6 protein. 51 2e-05
BC110606-1|AAI10607.1| 729|Homo sapiens EPHB6 protein protein. 51 2e-05
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 51 2e-05
AY280502-1|AAP20939.1| 1006|Homo sapiens EPHB6 protein. 51 2e-05
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 51 2e-05
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 51 2e-05
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 51 2e-05
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 51 2e-05
AK098622-1|BAC05355.1| 433|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AF107256-1|AAD03058.1| 804|Homo sapiens Eph-family protein prot... 51 2e-05
U73727-1|AAB51343.1| 1436|Homo sapiens receptor protein tyrosine... 51 3e-05
U71075-1|AAC51938.1| 1439|Homo sapiens protein tyrosine phosphat... 51 3e-05
U60289-1|AAB07074.1| 1436|Homo sapiens receptor protein tyrosine... 51 3e-05
AL645859-2|CAH72393.1| 1436|Homo sapiens protein tyrosine phosph... 51 3e-05
AL645859-1|CAH72394.1| 1446|Homo sapiens protein tyrosine phosph... 51 3e-05
AL590729-6|CAI14332.1| 1446|Homo sapiens protein tyrosine phosph... 51 3e-05
AL590729-5|CAI14331.1| 1436|Homo sapiens protein tyrosine phosph... 51 3e-05
AL049570-2|CAI20947.1| 1446|Homo sapiens protein tyrosine phosph... 51 3e-05
AL049570-1|CAI20946.1| 1436|Homo sapiens protein tyrosine phosph... 51 3e-05
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 51 3e-05
AB208855-1|BAD92092.1| 1243|Homo sapiens Receptor protein tyrosi... 51 3e-05
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 50 3e-05
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 50 3e-05
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 50 3e-05
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 50 3e-05
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 50 3e-05
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 50 3e-05
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 50 3e-05
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 50 3e-05
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 50 3e-05
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 50 3e-05
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 50 3e-05
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 50 3e-05
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 50 3e-05
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 50 3e-05
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 50 5e-05
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 50 5e-05
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 50 5e-05
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 50 5e-05
AK023273-1|BAB14500.1| 431|Homo sapiens protein ( Homo sapiens ... 50 5e-05
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 50 5e-05
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 50 5e-05
U60068-1|AAD10853.1| 354|Homo sapiens fibronectin protein. 50 6e-05
U60067-1|AAD11500.1| 379|Homo sapiens fibronectin protein. 50 6e-05
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 50 6e-05
AJ320527-1|CAC86916.1| 244|Homo sapiens fibronectin protein. 50 6e-05
AJ320526-1|CAC86915.1| 320|Homo sapiens fibronectin protein. 50 6e-05
AJ320525-1|CAC86914.1| 347|Homo sapiens fibronectin protein. 50 6e-05
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 50 6e-05
M17410-1|AAA59913.1| 355|Homo sapiens NCAM protein. 49 8e-05
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 49 8e-05
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 49 8e-05
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 49 8e-05
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 49 8e-05
AB086825-1|BAC45250.1| 788|Homo sapiens receptor protein tyrosi... 49 8e-05
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 49 8e-05
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 49 1e-04
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 49 1e-04
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 49 1e-04
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 49 1e-04
M24630-1|AAA52703.1| 1625|Homo sapiens hexabrachion protein. 49 1e-04
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 49 1e-04
BC111748-1|AAI11749.1| 1007|Homo sapiens roundabout homolog 4, m... 49 1e-04
BC111562-1|AAI11563.1| 1007|Homo sapiens roundabout homolog 4, m... 49 1e-04
BC039602-1|AAH39602.1| 1007|Homo sapiens roundabout homolog 4, m... 49 1e-04
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 49 1e-04
AY358083-1|AAQ88450.1| 1004|Homo sapiens magic roundabout protein. 49 1e-04
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 49 1e-04
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 49 1e-04
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 49 1e-04
AK074163-1|BAB84989.1| 702|Homo sapiens FLJ00236 protein protein. 49 1e-04
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 49 1e-04
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 49 1e-04
AK027852-1|BAB55411.1| 792|Homo sapiens protein ( Homo sapiens ... 49 1e-04
AF361473-1|AAL31867.1| 1007|Homo sapiens magic roundabout protein. 49 1e-04
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhesion
molecule splice variant protein.
Length = 1746
Score = 449 bits (1106), Expect = e-125
Identities = 248/712 (34%), Positives = 371/712 (52%), Gaps = 31/712 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 626 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 685
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E P GPPQ+V +
Sbjct: 686 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHL 745
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
E SS + VTW+ P++ L NG I GY +G++E ++ G + + +V+ +G
Sbjct: 746 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQFNIISVDTSG 796
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
+ TL L K Y +VVQA N +EDVPS PP +Q A S +
Sbjct: 797 DSEV-YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 855
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRY 353
S+ +SW NGILQG+RV Y W D +I + TT L GL +Y
Sbjct: 856 SISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQPSLELDGLEKY 910
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
TNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VSWLPP NG+
Sbjct: 911 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGI 970
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+ YT++ S + SP + S+ + WV A T G G ++ +
Sbjct: 971 IRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1027
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL----R 529
+TV P PARI +FS + TPW ++I L C VG P+PA W + G S + R
Sbjct: 1028 ITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR 1087
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L V + + S+
Sbjct: 1088 RSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSI 1147
Query: 590 HLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFN 648
L W +GGS I GY++ Y ++ + W + + L NL CGT Y+ +TA N
Sbjct: 1148 TLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1207
Query: 649 RIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
+G G +I+ A T G P K ++ ++NTT V + L W DGGC I F +EYR
Sbjct: 1208 GVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRP 1267
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
W + + + + + L A Y+L++ N+AG A NF T
Sbjct: 1268 FGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFAT 1317
Score = 82.6 bits (195), Expect = 7e-15
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 20/287 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 538 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 597
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 598 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 657
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 658 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 717
Query: 650 IGTGLPCDIVHAYTKGTVPVKPK---HSQMITLNTTTVTVWLDSWGDGGCGILY-FVIEY 705
IG P + + P P H + I+ + VT W GI+ + I Y
Sbjct: 718 IGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT-WKAPKKHLQNGIIRGYQIGY 776
Query: 706 REMSQP---QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
RE S Q+ ++S V+++ L Y L + A N AG
Sbjct: 777 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 823
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 150 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 208
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 209 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 253
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 459 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 518
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 519 KVSNDVGADVSKSMYLTVKIP 539
Score = 36.7 bits (81), Expect = 0.46
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 1/66 (1%)
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYT 567
+G P P W + + LE + R + G L I + +DSG+Y C V N +G +V
Sbjct: 1 LGHPEPDYRWLKDNMPLELSGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGR 59
Query: 568 VEVKVP 573
+ VK P
Sbjct: 60 LYVKQP 65
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 322 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 381
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 382 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 441
Query: 574 PQ 575
P+
Sbjct: 442 PK 443
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 2012
Score = 449 bits (1106), Expect = e-125
Identities = 248/712 (34%), Positives = 371/712 (52%), Gaps = 31/712 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 874 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 933
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E P GPPQ+V +
Sbjct: 934 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHL 993
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
E SS + VTW+ P++ L NG I GY +G++E ++ G + + +V+ +G
Sbjct: 994 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQFNIISVDTSG 1044
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
+ TL L K Y +VVQA N +EDVPS PP +Q A S +
Sbjct: 1045 DSEV-YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1103
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRY 353
S+ +SW NGILQG+RV Y W D +I + TT L GL +Y
Sbjct: 1104 SISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQPSLELDGLEKY 1158
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
TNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VSWLPP NG+
Sbjct: 1159 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGI 1218
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+ YT++ S + SP + S+ + WV A T G G ++ +
Sbjct: 1219 IRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1275
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL----R 529
+TV P PARI +FS + TPW ++I L C VG P+PA W + G S + R
Sbjct: 1276 ITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR 1335
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L V + + S+
Sbjct: 1336 RSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSI 1395
Query: 590 HLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFN 648
L W +GGS I GY++ Y ++ + W + + L NL CGT Y+ +TA N
Sbjct: 1396 TLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1455
Query: 649 RIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
+G G +I+ A T G P K ++ ++NTT V + L W DGGC I F +EYR
Sbjct: 1456 GVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRP 1515
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
W + + + + + L A Y+L++ N+AG A NF T
Sbjct: 1516 FGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFAT 1565
Score = 82.6 bits (195), Expect = 7e-15
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 20/287 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 786 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 845
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 846 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 905
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 906 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 965
Query: 650 IGTGLPCDIVHAYTKGTVPVKPK---HSQMITLNTTTVTVWLDSWGDGGCGILY-FVIEY 705
IG P + + P P H + I+ + VT W GI+ + I Y
Sbjct: 966 IGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT-WKAPKKHLQNGIIRGYQIGY 1024
Query: 706 REMSQP---QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
RE S Q+ ++S V+++ L Y L + A N AG
Sbjct: 1025 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 1071
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 398 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 456
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 457 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 501
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
+ + R+ P++S P+ + F + + L C +G P P W + + LE
Sbjct: 209 QSNSARLFVSDPANSAPSILDGFDHRKAMAG-QRVELPCKALGHPEPDYRWLKDNMPLEL 267
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ R + G L I + +DSG+Y C V N +G +V + VK P
Sbjct: 268 SGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 707 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 766
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 767 KVSNDVGADVSKSMYLTVKIP 787
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 570 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 629
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 630 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 574 PQ 575
P+
Sbjct: 690 PK 691
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1896
Score = 449 bits (1106), Expect = e-125
Identities = 248/712 (34%), Positives = 371/712 (52%), Gaps = 31/712 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 860 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 919
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E P GPPQ+V +
Sbjct: 920 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHL 979
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
E SS + VTW+ P++ L NG I GY +G++E ++ G + + +V+ +G
Sbjct: 980 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQFNIISVDTSG 1030
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
+ TL L K Y +VVQA N +EDVPS PP +Q A S +
Sbjct: 1031 DSEV-YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1089
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRY 353
S+ +SW NGILQG+RV Y W D +I + TT L GL +Y
Sbjct: 1090 SISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQPSLELDGLEKY 1144
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
TNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VSWLPP NG+
Sbjct: 1145 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGI 1204
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+ YT++ S + SP + S+ + WV A T G G ++ +
Sbjct: 1205 IRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1261
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL----R 529
+TV P PARI +FS + TPW ++I L C VG P+PA W + G S + R
Sbjct: 1262 ITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR 1321
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L V + + S+
Sbjct: 1322 RSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSI 1381
Query: 590 HLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFN 648
L W +GGS I GY++ Y ++ + W + + L NL CGT Y+ +TA N
Sbjct: 1382 TLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1441
Query: 649 RIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
+G G +I+ A T G P K ++ ++NTT V + L W DGGC I F +EYR
Sbjct: 1442 GVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRP 1501
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
W + + + + + L A Y+L++ N+AG A NF T
Sbjct: 1502 FGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFAT 1551
Score = 82.6 bits (195), Expect = 7e-15
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 20/287 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 772 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 831
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 832 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 891
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 892 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 951
Query: 650 IGTGLPCDIVHAYTKGTVPVKPK---HSQMITLNTTTVTVWLDSWGDGGCGILY-FVIEY 705
IG P + + P P H + I+ + VT W GI+ + I Y
Sbjct: 952 IGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT-WKAPKKHLQNGIIRGYQIGY 1010
Query: 706 REMSQP---QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
RE S Q+ ++S V+++ L Y L + A N AG
Sbjct: 1011 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 1057
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 384 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 442
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 443 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 487
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
+ + R+ P++S P+ + F + + L C +G P P W + + LE
Sbjct: 195 QSNSARLFVSDPANSAPSILDGFDHRKAMAG-QRVELPCKALGHPEPDYRWLKDNMPLEL 253
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ R + G L I + +DSG+Y C V N +G +V + VK P
Sbjct: 254 SGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 299
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 693 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 752
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 753 KVSNDVGADVSKSMYLTVKIP 773
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 556 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 615
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 616 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 675
Query: 574 PQ 575
P+
Sbjct: 676 PK 677
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhesion
molecule isoform CHD2-42 precursor variant protein.
Length = 2023
Score = 449 bits (1106), Expect = e-125
Identities = 248/712 (34%), Positives = 371/712 (52%), Gaps = 31/712 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 885 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 944
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E P GPPQ+V +
Sbjct: 945 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHL 1004
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
E SS + VTW+ P++ L NG I GY +G++E ++ G + + +V+ +G
Sbjct: 1005 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQFNIISVDTSG 1055
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
+ TL L K Y +VVQA N +EDVPS PP +Q A S +
Sbjct: 1056 DSEV-YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1114
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRY 353
S+ +SW NGILQG+RV Y W D +I + TT L GL +Y
Sbjct: 1115 SISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQPSLELDGLEKY 1169
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
TNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VSWLPP NG+
Sbjct: 1170 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGI 1229
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+ YT++ S + SP + S+ + WV A T G G ++ +
Sbjct: 1230 IRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1286
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL----R 529
+TV P PARI +FS + TPW ++I L C VG P+PA W + G S + R
Sbjct: 1287 ITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR 1346
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L V + + S+
Sbjct: 1347 RSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSI 1406
Query: 590 HLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFN 648
L W +GGS I GY++ Y ++ + W + + L NL CGT Y+ +TA N
Sbjct: 1407 TLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1466
Query: 649 RIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
+G G +I+ A T G P K ++ ++NTT V + L W DGGC I F +EYR
Sbjct: 1467 GVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRP 1526
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
W + + + + + L A Y+L++ N+AG A NF T
Sbjct: 1527 FGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFAT 1576
Score = 82.6 bits (195), Expect = 7e-15
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 20/287 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 797 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 856
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 857 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 916
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 917 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 976
Query: 650 IGTGLPCDIVHAYTKGTVPVKPK---HSQMITLNTTTVTVWLDSWGDGGCGILY-FVIEY 705
IG P + + P P H + I+ + VT W GI+ + I Y
Sbjct: 977 IGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT-WKAPKKHLQNGIIRGYQIGY 1035
Query: 706 REMSQP---QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
RE S Q+ ++S V+++ L Y L + A N AG
Sbjct: 1036 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 1082
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 409 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 467
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 468 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 512
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
+ + R+ P++S P+ + F + + L C +G P P W + + LE
Sbjct: 220 QSNSARLFVSDPANSAPSILDGFEHRKAMAG-QRVELPCKALGHPEPDYRWLKDNMPLEL 278
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ R + G L I + +DSG+Y C V N +G +V + VK P
Sbjct: 279 SGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 324
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 718 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 777
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 778 KVSNDVGADVSKSMYLTVKIP 798
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 581 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 640
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 641 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 700
Query: 574 PQ 575
P+
Sbjct: 701 PK 702
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1571
Score = 445 bits (1097), Expect = e-124
Identities = 245/704 (34%), Positives = 368/704 (52%), Gaps = 31/704 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 874 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 933
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E P GPPQ+V +
Sbjct: 934 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHL 993
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
E SS + VTW+ P++ L NG I GY +G++E ++ G + + +V+ +G
Sbjct: 994 EPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQFNIISVDTSG 1044
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
+ TL L K Y +VVQA N +EDVPS PP +Q A S +
Sbjct: 1045 DSEV-YTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPE 1103
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRY 353
S+ +SW NGILQG+RV Y W D +I + TT L GL +Y
Sbjct: 1104 SISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQPSLELDGLEKY 1158
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
TNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VSWLPP NG+
Sbjct: 1159 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGI 1218
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+ YT++ S + SP + S+ + WV A T G G ++ +
Sbjct: 1219 IRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1275
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL----R 529
+TV P PARI +FS + TPW ++I L C VG P+PA W + G S + R
Sbjct: 1276 ITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR 1335
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L V + + S+
Sbjct: 1336 RSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSI 1395
Query: 590 HLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFN 648
L W +GGS I GY++ Y ++ + W + + L NL CGT Y+ +TA N
Sbjct: 1396 TLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1455
Query: 649 RIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
+G G +I+ A T G P K ++ ++NTT V + L W DGGC I F +EYR
Sbjct: 1456 GVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRP 1515
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
W + + + + + L A Y+L++ N+AG A
Sbjct: 1516 FGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCA 1557
Score = 82.6 bits (195), Expect = 7e-15
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 20/287 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 786 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 845
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 846 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 905
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 906 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 965
Query: 650 IGTGLPCDIVHAYTKGTVPVKPK---HSQMITLNTTTVTVWLDSWGDGGCGILY-FVIEY 705
IG P + + P P H + I+ + VT W GI+ + I Y
Sbjct: 966 IGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT-WKAPKKHLQNGIIRGYQIGY 1024
Query: 706 REMSQP---QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
RE S Q+ ++S V+++ L Y L + A N AG
Sbjct: 1025 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG 1071
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 398 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 456
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 457 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 501
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
+ + R+ P++S P+ + F + + L C +G P P W + + LE
Sbjct: 209 QSNSARLFVSDPANSAPSILDGFDHRKAMAG-QRVELPCKALGHPEPDYRWLKDNMPLEL 267
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ R + G L I + +DSG+Y C V N +G +V + VK P
Sbjct: 268 SGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 707 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 766
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 767 KVSNDVGADVSKSMYLTVKIP 787
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 570 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 629
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 630 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 574 PQ 575
P+
Sbjct: 690 PK 691
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 432 bits (1064), Expect = e-120
Identities = 245/725 (33%), Positives = 387/725 (53%), Gaps = 36/725 (4%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
L+ Q P P + + + ++R++ + WTQ + GNS I + ++YK +SW +
Sbjct: 942 LTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 1001
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++ A++ +L PA+ Y +R+ + N++G+SEPS+ + ++T E P GPP DV ++ +S
Sbjct: 1002 PTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQ 1061
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ VTW+ P+++L NG I GY +G++E NS G G Y++ ++ G +
Sbjct: 1062 SIQVTWKAPKKELQNGVIRGYQIGYRE-NS-------PGSNG-QYSIVEMKATGDSEV-Y 1111
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
TL L+K A Y VVVQA+N +EDVPS PP ++ +++S +SW
Sbjct: 1112 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISW 1171
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRYTNYSVT 359
PP NG+L+GYRV + W D ++ + TT L G+ ++TNYSV
Sbjct: 1172 SEPPRSTLNGVLKGYRVIF-----WSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQ 1226
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A+T AGDGVR++ +Y T+EDVP PA IKA SS + ++VSWLPP+ PNGV+ YT+
Sbjct: 1227 VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI 1286
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ S G + + SP L + + + WV+A T G G ++ VT+ P+
Sbjct: 1287 FCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA 1345
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM----NGVGLESTLRKNVSSD 535
PA+I SF + TPW +++ L CN VG PAPA WT + + + + + ++
Sbjct: 1346 GKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN 1405
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD 595
GTL + ++ DSG YTC+ N G D + + V+VPP P L V + A S+ L W
Sbjct: 1406 GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIP 1465
Query: 596 QGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+GGS I G+V+ Y ++ +W+++ + + L +L CGT Y++ + A N +G+G
Sbjct: 1466 GDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1525
Query: 655 PCDIVHAYTKGTVPVKPKHSQMIT-LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
+I+ A T G P K + T +N+T + L W +GGC I V+EYR W
Sbjct: 1526 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAW 1585
Query: 714 R-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXP 772
+ L +NS + VF ++ L A Y+LR+ A N+AG N T P
Sbjct: 1586 QGLRANS---SGEVF-LTELREATWYELRMRACNSAGCG----NETAQFATLDYDGSTIP 1637
Query: 773 PIPAA 777
PI +A
Sbjct: 1638 PIKSA 1642
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 12/224 (5%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
TL + DS ++C N +G D + V+ PP PP L + + A S++L+W+ +
Sbjct: 911 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQR 970
Query: 597 GDGGSPILGYVINYKREHGDWEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGT 652
DG S I G+ I YK + W+ Q S + + +L + Y + + +FN+IG
Sbjct: 971 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR 1030
Query: 653 GLPCDIVHAYTKGTVPVKPKHS---QMITLNTTTVTVWLDSWGDGGCGILY-FVIEYREM 708
P + T+ P P Q +T + VT W + G++ + I YRE
Sbjct: 1031 SEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVT-WKAPKKELQNGVIRGYQIGYREN 1089
Query: 709 ---SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S Q+ +V V+++ L A Y + + A N AG
Sbjct: 1090 SPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1133
Score = 61.3 bits (142), Expect = 2e-08
Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 22/247 (8%)
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEE-DVPSAPADIKAAVS 395
TK+I+GL T+S LR + +C T A + + V P +K +
Sbjct: 333 TKRITGL--TISDLRTEDS-GTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIG 389
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
S +++S SP + Y V+ D E R LS TL +++ +
Sbjct: 390 ST--VILSCALTGSPEFTIRWYRNTELVLPD---EAISIRGLSNETLLITSAQKSHSGAY 444
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q + + + + A + D P ++SFS +V P E SL C G P P
Sbjct: 445 QCFATRKAQTAQDFAI----IALEDGTPRIVSSFSEKVVNPG-EQFSLMCAAKGAPPPTV 499
Query: 516 TWTMNGVGL--ESTLRKN--VSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYT 567
TW ++ + + + R N SDGT + ++ Q D G Y C+ N+ G E
Sbjct: 500 TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 559
Query: 568 VEVKVPP 574
+ V+ PP
Sbjct: 560 INVRGPP 566
Score = 55.6 bits (128), Expect = 9e-07
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+S+I + R T+ L S + E + S R + S TR G R+ P++
Sbjct: 226 VSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAE 283
Query: 481 SVPARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
S+P + F V W + L C G P PA W +G L + R G LT
Sbjct: 284 SIPTILDGFHSQEV--WAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG-LT 340
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVT 565
IS ++ DSG Y C V N G E T
Sbjct: 341 ISDLRTEDSGTYICEVTNTFGSAEAT 366
Score = 45.6 bits (103), Expect = 0.001
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPP-RATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++ DG M +T+SH P R + +A +G E + V S
Sbjct: 508 IVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS 567
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
+ A RNI + ++C +G P + W + + L R+ V +GTL ++
Sbjct: 568 IRAM-----RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLT 622
Query: 542 MTQSA-DSGNYTCSVENIHGRDEVTYTVE--VKVPP 574
Q D G Y CSV I + ++ +V VKVPP
Sbjct: 623 DVQKGMDEGEYLCSV-LIQPQLSISQSVHVAVKVPP 657
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK-EAPESWPST 117
D I +L QVP + V + +I ++W G S I +++QY + E W
Sbjct: 1432 DTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW--- 1488
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ V + S S + +L+ T Y +++ A+N +G S+ ++ T PS
Sbjct: 1489 -KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPS 1540
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule DSCAML1 protein.
Length = 2053
Score = 432 bits (1064), Expect = e-120
Identities = 245/725 (33%), Positives = 387/725 (53%), Gaps = 36/725 (4%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
L+ Q P P + + + ++R++ + WTQ + GNS I + ++YK +SW +
Sbjct: 882 LTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 941
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++ A++ +L PA+ Y +R+ + N++G+SEPS+ + ++T E P GPP DV ++ +S
Sbjct: 942 PTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQ 1001
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ VTW+ P+++L NG I GY +G++E NS G G Y++ ++ G +
Sbjct: 1002 SIQVTWKAPKKELQNGVIRGYQIGYRE-NS-------PGSNG-QYSIVEMKATGDSEV-Y 1051
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
TL L+K A Y VVVQA+N +EDVPS PP ++ +++S +SW
Sbjct: 1052 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISW 1111
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRYTNYSVT 359
PP NG+L+GYRV + W D ++ + TT L G+ ++TNYSV
Sbjct: 1112 SEPPRSTLNGVLKGYRVIF-----WSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQ 1166
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A+T AGDGVR++ +Y T+EDVP PA IKA SS + ++VSWLPP+ PNGV+ YT+
Sbjct: 1167 VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI 1226
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ S G + + SP L + + + WV+A T G G ++ VT+ P+
Sbjct: 1227 FCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA 1285
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM----NGVGLESTLRKNVSSD 535
PA+I SF + TPW +++ L CN VG PAPA WT + + + + + ++
Sbjct: 1286 GKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN 1345
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD 595
GTL + ++ DSG YTC+ N G D + + V+VPP P L V + A S+ L W
Sbjct: 1346 GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIP 1405
Query: 596 QGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+GGS I G+V+ Y ++ +W+++ + + L +L CGT Y++ + A N +G+G
Sbjct: 1406 GDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1465
Query: 655 PCDIVHAYTKGTVPVKPKHSQMIT-LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
+I+ A T G P K + T +N+T + L W +GGC I V+EYR W
Sbjct: 1466 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAW 1525
Query: 714 R-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXP 772
+ L +NS + VF ++ L A Y+LR+ A N+AG N T P
Sbjct: 1526 QGLRANS---SGEVF-LTELREATWYELRMRACNSAGCG----NETAQFATLDYDGSTIP 1577
Query: 773 PIPAA 777
PI +A
Sbjct: 1578 PIKSA 1582
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 12/224 (5%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
TL + DS ++C N +G D + V+ PP PP L + + A S++L+W+ +
Sbjct: 851 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQR 910
Query: 597 GDGGSPILGYVINYKREHGDWEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGT 652
DG S I G+ I YK + W+ Q S + + +L + Y + + +FN+IG
Sbjct: 911 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR 970
Query: 653 GLPCDIVHAYTKGTVPVKPKHS---QMITLNTTTVTVWLDSWGDGGCGILY-FVIEYREM 708
P + T+ P P Q +T + VT W + G++ + I YRE
Sbjct: 971 SEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVT-WKAPKKELQNGVIRGYQIGYREN 1029
Query: 709 ---SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S Q+ +V V+++ L A Y + + A N AG
Sbjct: 1030 SPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073
Score = 61.3 bits (142), Expect = 2e-08
Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 22/247 (8%)
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEE-DVPSAPADIKAAVS 395
TK+I+GL T+S LR + +C T A + + V P +K +
Sbjct: 273 TKRITGL--TISDLRTEDS-GTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIG 329
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
S +++S SP + Y V+ D E R LS TL +++ +
Sbjct: 330 ST--VILSCALTGSPEFTIRWYRNTELVLPD---EAISIRGLSNETLLITSAQKSHSGAY 384
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q + + + + A + D P ++SFS +V P E SL C G P P
Sbjct: 385 QCFATRKAQTAQDFAI----IALEDGTPRIVSSFSEKVVNPG-EQFSLMCAAKGAPPPTV 439
Query: 516 TWTMNGVGL--ESTLRKN--VSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYT 567
TW ++ + + + R N SDGT + ++ Q D G Y C+ N+ G E
Sbjct: 440 TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 499
Query: 568 VEVKVPP 574
+ V+ PP
Sbjct: 500 INVRGPP 506
Score = 56.4 bits (130), Expect = 5e-07
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+S+I + R T+ L S + E + S R + S TR G R+ P++
Sbjct: 166 VSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAE 223
Query: 481 SVPARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
S+P + F V W + L C G P PA W +G L + R G LT
Sbjct: 224 SIPTILDGFHSQEV--WAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG-LT 280
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVT 565
IS ++ DSG Y C V N G E T
Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEAT 306
Score = 45.6 bits (103), Expect = 0.001
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPP-RATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++ DG M +T+SH P R + +A +G E + V S
Sbjct: 448 IVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS 507
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
+ A RNI + ++C +G P + W + + L R+ V +GTL ++
Sbjct: 508 IRAM-----RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLT 562
Query: 542 MTQSA-DSGNYTCSVENIHGRDEVTYTVE--VKVPP 574
Q D G Y CSV I + ++ +V VKVPP
Sbjct: 563 DVQKGMDEGEYLCSV-LIQPQLSISQSVHVAVKVPP 597
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK-EAPESWPST 117
D I +L QVP + V + +I ++W G S I +++QY + E W
Sbjct: 1372 DTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW--- 1428
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ V + S S + +L+ T Y +++ A+N +G S+ ++ T PS
Sbjct: 1429 -KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPS 1480
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1b protein.
Length = 1842
Score = 432 bits (1064), Expect = e-120
Identities = 245/725 (33%), Positives = 387/725 (53%), Gaps = 36/725 (4%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
L+ Q P P + + + ++R++ + WTQ + GNS I + ++YK +SW +
Sbjct: 671 LTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 730
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++ A++ +L PA+ Y +R+ + N++G+SEPS+ + ++T E P GPP DV ++ +S
Sbjct: 731 PTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQ 790
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ VTW+ P+++L NG I GY +G++E NS G G Y++ ++ G +
Sbjct: 791 SIQVTWKAPKKELQNGVIRGYQIGYRE-NS-------PGSNG-QYSIVEMKATGDSEV-Y 840
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
TL L+K A Y VVVQA+N +EDVPS PP ++ +++S +SW
Sbjct: 841 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISW 900
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRYTNYSVT 359
PP NG+L+GYRV + W D ++ + TT L G+ ++TNYSV
Sbjct: 901 SEPPRSTLNGVLKGYRVIF-----WSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQ 955
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A+T AGDGVR++ +Y T+EDVP PA IKA SS + ++VSWLPP+ PNGV+ YT+
Sbjct: 956 VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI 1015
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ S G + + SP L + + + WV+A T G G ++ VT+ P+
Sbjct: 1016 FCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA 1074
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM----NGVGLESTLRKNVSSD 535
PA+I SF + TPW +++ L CN VG PAPA WT + + + + + ++
Sbjct: 1075 GKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN 1134
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD 595
GTL + ++ DSG YTC+ N G D + + V+VPP P L V + A S+ L W
Sbjct: 1135 GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIP 1194
Query: 596 QGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+GGS I G+V+ Y ++ +W+++ + + L +L CGT Y++ + A N +G+G
Sbjct: 1195 GDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1254
Query: 655 PCDIVHAYTKGTVPVKPKHSQMIT-LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
+I+ A T G P K + T +N+T + L W +GGC I V+EYR W
Sbjct: 1255 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAW 1314
Query: 714 R-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXP 772
+ L +NS + VF ++ L A Y+LR+ A N+AG N T P
Sbjct: 1315 QGLRANS---SGEVF-LTELREATWYELRMRACNSAGCG----NETAQFATLDYDGSTIP 1366
Query: 773 PIPAA 777
PI +A
Sbjct: 1367 PIKSA 1371
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 12/224 (5%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
TL + DS ++C N +G D + V+ PP PP L + + A S++L+W+ +
Sbjct: 640 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQR 699
Query: 597 GDGGSPILGYVINYKREHGDWEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGT 652
DG S I G+ I YK + W+ Q S + + +L + Y + + +FN+IG
Sbjct: 700 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR 759
Query: 653 GLPCDIVHAYTKGTVPVKPKHS---QMITLNTTTVTVWLDSWGDGGCGILY-FVIEYREM 708
P + T+ P P Q +T + VT W + G++ + I YRE
Sbjct: 760 SEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVT-WKAPKKELQNGVIRGYQIGYREN 818
Query: 709 ---SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S Q+ +V V+++ L A Y + + A N AG
Sbjct: 819 SPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 862
Score = 61.3 bits (142), Expect = 2e-08
Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 22/247 (8%)
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEE-DVPSAPADIKAAVS 395
TK+I+GL T+S LR + +C T A + + V P +K +
Sbjct: 62 TKRITGL--TISDLRTEDS-GTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIG 118
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
S +++S SP + Y V+ D E R LS TL +++ +
Sbjct: 119 ST--VILSCALTGSPEFTIRWYRNTELVLPD---EAISIRGLSNETLLITSAQKSHSGAY 173
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q + + + + A + D P ++SFS +V P E SL C G P P
Sbjct: 174 QCFATRKAQTAQDFAI----IALEDGTPRIVSSFSEKVVNPG-EQFSLMCAAKGAPPPTV 228
Query: 516 TWTMNGVGL--ESTLRKN--VSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYT 567
TW ++ + + + R N SDGT + ++ Q D G Y C+ N+ G E
Sbjct: 229 TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 288
Query: 568 VEVKVPP 574
+ V+ PP
Sbjct: 289 INVRGPP 295
Score = 45.6 bits (103), Expect = 0.001
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPP-RATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++ DG M +T+SH P R + +A +G E + V S
Sbjct: 237 IVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS 296
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
+ A RNI + ++C +G P + W + + L R+ V +GTL ++
Sbjct: 297 IRAM-----RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLT 351
Query: 542 MTQSA-DSGNYTCSVENIHGRDEVTYTVE--VKVPP 574
Q D G Y CSV I + ++ +V VKVPP
Sbjct: 352 DVQKGMDEGEYLCSV-LIQPQLSISQSVHVAVKVPP 386
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+++ L C G P PA W +G L + R G LTIS ++ DSG Y C V N
Sbjct: 30 DSLQLPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITG-LTISDLRTEDSGTYICEVTNT 88
Query: 559 HGRDEVT 565
G E T
Sbjct: 89 FGSAEAT 95
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK-EAPESWPST 117
D I +L QVP + V + +I ++W G S I +++QY + E W
Sbjct: 1161 DTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW--- 1217
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ V + S S + +L+ T Y +++ A+N +G S+ ++ T PS
Sbjct: 1218 -KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPS 1269
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1a protein.
Length = 2053
Score = 432 bits (1064), Expect = e-120
Identities = 245/725 (33%), Positives = 387/725 (53%), Gaps = 36/725 (4%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
L+ Q P P + + + ++R++ + WTQ + GNS I + ++YK +SW +
Sbjct: 882 LTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 941
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++ A++ +L PA+ Y +R+ + N++G+SEPS+ + ++T E P GPP DV ++ +S
Sbjct: 942 PTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQ 1001
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ VTW+ P+++L NG I GY +G++E NS G G Y++ ++ G +
Sbjct: 1002 SIQVTWKAPKKELQNGVIRGYQIGYRE-NS-------PGSNG-QYSIVEMKATGDSEV-Y 1051
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
TL L+K A Y VVVQA+N +EDVPS PP ++ +++S +SW
Sbjct: 1052 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISW 1111
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRYTNYSVT 359
PP NG+L+GYRV + W D ++ + TT L G+ ++TNYSV
Sbjct: 1112 SEPPRSTLNGVLKGYRVIF-----WSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQ 1166
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A+T AGDGVR++ +Y T+EDVP PA IKA SS + ++VSWLPP+ PNGV+ YT+
Sbjct: 1167 VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI 1226
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ S G + + SP L + + + WV+A T G G ++ VT+ P+
Sbjct: 1227 FCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA 1285
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM----NGVGLESTLRKNVSSD 535
PA+I SF + TPW +++ L CN VG PAPA WT + + + + + ++
Sbjct: 1286 GKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN 1345
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD 595
GTL + ++ DSG YTC+ N G D + + V+VPP P L V + A S+ L W
Sbjct: 1346 GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIP 1405
Query: 596 QGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+GGS I G+V+ Y ++ +W+++ + + L +L CGT Y++ + A N +G+G
Sbjct: 1406 GDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1465
Query: 655 PCDIVHAYTKGTVPVKPKHSQMIT-LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
+I+ A T G P K + T +N+T + L W +GGC I V+EYR W
Sbjct: 1466 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAW 1525
Query: 714 R-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXP 772
+ L +NS + VF ++ L A Y+LR+ A N+AG N T P
Sbjct: 1526 QGLRANS---SGEVF-LTELREATWYELRMRACNSAGCG----NETAQFATLDYDGSTIP 1577
Query: 773 PIPAA 777
PI +A
Sbjct: 1578 PIKSA 1582
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 12/224 (5%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
TL + DS ++C N +G D + V+ PP PP L + + A S++L+W+ +
Sbjct: 851 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQR 910
Query: 597 GDGGSPILGYVINYKREHGDWEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGT 652
DG S I G+ I YK + W+ Q S + + +L + Y + + +FN+IG
Sbjct: 911 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR 970
Query: 653 GLPCDIVHAYTKGTVPVKPKHS---QMITLNTTTVTVWLDSWGDGGCGILY-FVIEYREM 708
P + T+ P P Q +T + VT W + G++ + I YRE
Sbjct: 971 SEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVT-WKAPKKELQNGVIRGYQIGYREN 1029
Query: 709 ---SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S Q+ +V V+++ L A Y + + A N AG
Sbjct: 1030 SPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073
Score = 61.3 bits (142), Expect = 2e-08
Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 22/247 (8%)
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEE-DVPSAPADIKAAVS 395
TK+I+GL T+S LR + +C T A + + V P +K +
Sbjct: 273 TKRITGL--TISDLRTEDS-GTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIG 329
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
S +++S SP + Y V+ D E R LS TL +++ +
Sbjct: 330 ST--VILSCALTGSPEFTIRWYRNTELVLPD---EAISIRGLSNETLLITSAQKSHSGAY 384
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q + + + + A + D P ++SFS +V P E SL C G P P
Sbjct: 385 QCFATRKAQTAQDFAI----IALEDGTPRIVSSFSEKVVNPG-EQFSLMCAAKGAPPPTV 439
Query: 516 TWTMNGVGL--ESTLRKN--VSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYT 567
TW ++ + + + R N SDGT + ++ Q D G Y C+ N+ G E
Sbjct: 440 TWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 499
Query: 568 VEVKVPP 574
+ V+ PP
Sbjct: 500 INVRGPP 506
Score = 55.6 bits (128), Expect = 9e-07
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+S+I + R T+ L S + E + S R + S TR G R+ P++
Sbjct: 166 VSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAE 223
Query: 481 SVPARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
S+P + F V W + L C G P PA W +G L + R G LT
Sbjct: 224 SIPTILDGFHSQEV--WAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG-LT 280
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVT 565
IS ++ DSG Y C V N G E T
Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEAT 306
Score = 43.2 bits (97), Expect = 0.005
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPP-RATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++ DG M +T+S+ P R + +A +G E + V S
Sbjct: 448 IVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS 507
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
+ A RNI + ++C +G P + W + + L R+ V +GTL ++
Sbjct: 508 IRAM-----RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLT 562
Query: 542 MTQSA-DSGNYTCSVENIHGRDEVTYTVE--VKVPP 574
Q D G Y CSV I + ++ +V VKVPP
Sbjct: 563 DVQKGMDEGEYLCSV-LIQPQLSISQSVHVAVKVPP 597
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK-EAPESWPST 117
D I +L QVP + V + +I ++W G S I +++QY + E W
Sbjct: 1372 DTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW--- 1428
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ V + S S + +L+ T Y +++ A+N +G S+ ++ T PS
Sbjct: 1429 -KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPS 1480
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 432 bits (1064), Expect = e-120
Identities = 245/725 (33%), Positives = 387/725 (53%), Gaps = 36/725 (4%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
L+ Q P P + + + ++R++ + WTQ + GNS I + ++YK +SW +
Sbjct: 921 LTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 980
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++ A++ +L PA+ Y +R+ + N++G+SEPS+ + ++T E P GPP DV ++ +S
Sbjct: 981 PTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQ 1040
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ VTW+ P+++L NG I GY +G++E NS G G Y++ ++ G +
Sbjct: 1041 SIQVTWKAPKKELQNGVIRGYQIGYRE-NS-------PGSNG-QYSIVEMKATGDSEV-Y 1090
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
TL L+K A Y VVVQA+N +EDVPS PP ++ +++S +SW
Sbjct: 1091 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISW 1150
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-----LSGLRRYTNYSVT 359
PP NG+L+GYRV + W D ++ + TT L G+ ++TNYSV
Sbjct: 1151 SEPPRSTLNGVLKGYRVIF-----WSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQ 1205
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A+T AGDGVR++ +Y T+EDVP PA IKA SS + ++VSWLPP+ PNGV+ YT+
Sbjct: 1206 VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI 1265
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ S G + + SP L + + + WV+A T G G ++ VT+ P+
Sbjct: 1266 FCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPA 1324
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM----NGVGLESTLRKNVSSD 535
PA+I SF + TPW +++ L CN VG PAPA WT + + + + + ++
Sbjct: 1325 GKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTN 1384
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD 595
GTL + ++ DSG YTC+ N G D + + V+VPP P L V + A S+ L W
Sbjct: 1385 GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIP 1444
Query: 596 QGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+GGS I G+V+ Y ++ +W+++ + + L +L CGT Y++ + A N +G+G
Sbjct: 1445 GDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1504
Query: 655 PCDIVHAYTKGTVPVKPKHSQMIT-LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
+I+ A T G P K + T +N+T + L W +GGC I V+EYR W
Sbjct: 1505 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAW 1564
Query: 714 R-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXP 772
+ L +NS + VF ++ L A Y+LR+ A N+AG N T P
Sbjct: 1565 QGLRANS---SGEVF-LTELREATWYELRMRACNSAGCG----NETAQFATLDYDGSTIP 1616
Query: 773 PIPAA 777
PI +A
Sbjct: 1617 PIKSA 1621
Score = 77.8 bits (183), Expect = 2e-13
Identities = 60/224 (26%), Positives = 99/224 (44%), Gaps = 12/224 (5%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
TL + DS ++C N +G D + V+ PP PP L + + A S++L+W+ +
Sbjct: 890 TLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKARSMNLRWTQR 949
Query: 597 GDGGSPILGYVINYKREHGDWEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGT 652
DG S I G+ I YK + W+ Q S + + +L + Y + + +FN+IG
Sbjct: 950 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR 1009
Query: 653 GLPCDIVHAYTKGTVPVKPKHS---QMITLNTTTVTVWLDSWGDGGCGILY-FVIEYREM 708
P + T+ P P Q +T + VT W + G++ + I YRE
Sbjct: 1010 SEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVT-WKAPKKELQNGVIRGYQIGYREN 1068
Query: 709 ---SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S Q+ +V V+++ L A Y + + A N AG
Sbjct: 1069 SPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1112
Score = 61.3 bits (142), Expect = 2e-08
Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 22/247 (8%)
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEE-DVPSAPADIKAAVS 395
TK+I+GL T+S LR + +C T A + + V P +K +
Sbjct: 312 TKRITGL--TISDLRTEDS-GTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIG 368
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
S +++S SP + Y V+ D E R LS TL +++ +
Sbjct: 369 ST--VILSCALTGSPEFTIRWYRNTELVLPD---EAISIRGLSNETLLITSAQKSHSGAY 423
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q + + + + A + D P ++SFS +V P E SL C G P P
Sbjct: 424 QCFATRKAQTAQDFAI----IALEDGTPRIVSSFSEKVVNPG-EQFSLMCAAKGAPPPTV 478
Query: 516 TWTMNGVGL--ESTLRKN--VSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYT 567
TW ++ + + + R N SDGT + ++ Q D G Y C+ N+ G E
Sbjct: 479 TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 538
Query: 568 VEVKVPP 574
+ V+ PP
Sbjct: 539 INVRGPP 545
Score = 56.4 bits (130), Expect = 5e-07
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+S+I + R T+ L S + E + S R + S TR G R+ P++
Sbjct: 205 VSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAE 262
Query: 481 SVPARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
S+P + F V W + L C G P PA W +G L + R G LT
Sbjct: 263 SIPTILDGFHSQEV--WAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG-LT 319
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVT 565
IS ++ DSG Y C V N G E T
Sbjct: 320 ISDLRTEDSGTYICEVTNTFGSAEAT 345
Score = 45.6 bits (103), Expect = 0.001
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPP-RATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++ DG M +T+SH P R + +A +G E + V S
Sbjct: 487 IVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS 546
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
+ A RNI + ++C +G P + W + + L R+ V +GTL ++
Sbjct: 547 IRAM-----RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLT 601
Query: 542 MTQSA-DSGNYTCSVENIHGRDEVTYTVE--VKVPP 574
Q D G Y CSV I + ++ +V VKVPP
Sbjct: 602 DVQKGMDEGEYLCSV-LIQPQLSISQSVHVAVKVPP 636
Score = 42.3 bits (95), Expect = 0.009
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK-EAPESWPST 117
D I +L QVP + V + +I ++W G S I +++QY + E W
Sbjct: 1411 DTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEW--- 1467
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ V + S S + +L+ T Y +++ A+N +G S+ ++ T PS
Sbjct: 1468 -KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPS 1519
>AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 1029
Score = 369 bits (909), Expect = e-101
Identities = 209/602 (34%), Positives = 307/602 (50%), Gaps = 31/602 (5%)
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P GPPQ+V +E SS + VTW+ P++ L NG I GY +G++E ++ G
Sbjct: 1 PDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTG---------GNFQ 51
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG 288
+ + +V+ +G + T L L K Y +VVQA N +EDVPS PP
Sbjct: 52 FNIISVDTSGDSEVYT-LDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPE 110
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-- 346
+Q A S +S+ +SW NGILQG+RV Y W D +I + TT
Sbjct: 111 NVQAIATSPESISISWSTLSKEALNGILQGFRVIY-----WANLMDGELGEIKNITTTQP 165
Query: 347 ---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
L GL +YTNYS+ V AFT AGDGVR+ ++ T+EDVP PA +KAA +S + + VS
Sbjct: 166 SLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVS 225
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
WLPP NG++ YT++ S + SP + S+ + WV A T
Sbjct: 226 WLPPLKLNGIIRKYTVFCS---HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVT 282
Query: 464 RLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVG 523
G G ++ ++TV P PARI +FS + TPW ++I L C VG P+PA W + G
Sbjct: 283 SAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG 342
Query: 524 LESTL----RKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
S + R+++ S+G+ I ++ DSG Y+C N G DE+ ++V+VPP P L
Sbjct: 343 TPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRL 402
Query: 580 AVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGT 638
V + + S+ L W +GGS I GY++ Y ++ + W + + L NL CGT
Sbjct: 403 TVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGT 462
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWLDSWGDGGCG 697
Y+ +TA N +G G +I+ A T G P K ++ ++NTT V + L W DGGC
Sbjct: 463 WYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCP 522
Query: 698 ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNF 757
I F +EYR W + + + + + L A Y+L++ N+AG A NF
Sbjct: 523 ITSFTLEYRPFGTTVWTTAQRT--SLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANF 580
Query: 758 TT 759
T
Sbjct: 581 AT 582
Score = 94.3 bits (224), Expect = 2e-18
Identities = 89/323 (27%), Positives = 140/323 (43%), Gaps = 27/323 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPE--SWPSTPQKVIVPGSVT 128
P+ + + S++I+++W P + N I Y + Y+E ++ V G
Sbjct: 5 PQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSE 64
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ NL T Y L + A NR G SQ + TT E+VPS PP++V+ A S + +
Sbjct: 65 VYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISI 124
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W ++ NG + G+ V + +N + G G ++ T + L G
Sbjct: 125 SWSTLSKEALNGILQGFRVIYW---AN----LMDGELG------EIKNITTTQPSLELDG 171
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K+ Y++ V A+ EDVP PP ++ A S+ V VSW PP
Sbjct: 172 LEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG-PPAGVKAAAASASMVFVSWLPP- 229
Query: 309 MRGRNGILQGYRVTYA-PVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
NGI++ Y V + P +A S + L R YSV V A T+AG
Sbjct: 230 -LKLNGIIRKYTVFCSHPYPTVISEFEASPDSFS---YRIPNLSRNRQYSVWVVAVTSAG 285
Query: 368 DGVRAAPVYCHTEEDVPSAPADI 390
G + + T E + APA I
Sbjct: 286 RGNSSEII---TVEPLAKAPARI 305
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE-APESWPSTPQKVI 122
+L QVP + V S +I +SW G S I YI+QY E E W S P
Sbjct: 390 NLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFP---- 445
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
+ S S ++NL+ T Y + A+N +G S+ ++ T + P
Sbjct: 446 ISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEP 492
>BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein.
Length = 1805
Score = 198 bits (483), Expect = 9e-50
Identities = 188/733 (25%), Positives = 320/733 (43%), Gaps = 63/733 (8%)
Query: 53 DSKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPE 112
DS+ + LR+ L H PE P + + R I ++WT+P+ GNSP+I YI++ E
Sbjct: 211 DSR-SAHLRVRQLPH-APEHPV-ATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNA 267
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSG 171
W T V TS +V+ L PA SY R+ A N +G+ + S+ + V+ EE P+
Sbjct: 268 PW--TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 325
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
PPQ+V +++ +++ W+PP NG + GY + + +A P G Y
Sbjct: 326 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRY---------CLAGLPVG--YQF 374
Query: 232 RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQ 291
+ + A + L L Y + V AYNS ++ VP++PPG +
Sbjct: 375 KNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVH 432
Query: 292 CNALSSQSVRVSWEPPPMRGRNGILQGYR-VTYAPVTDWYGNEDAVTKQIS-GLHTT-LS 348
A +S ++R +W P + NGI QGY+ + + P + +H +S
Sbjct: 433 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 492
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
GL+++T Y +V FT GDG R+ P T EDVP + + + VSW P
Sbjct: 493 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 552
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
NG+L GY + TH L TL + + T+ V+A T G+G
Sbjct: 553 EKNGILTGYRISWEEYNRTNTRVTH--YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG 610
Query: 469 E--ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN------ 520
+ A+ + + +P + +P T+ + + P + G + W +
Sbjct: 611 QVSASTISSGVPPE-LPGPPTNLGISNIGPRSVTLQFRPGYDG-KTSISRWLVEAQVGVV 668
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTC-----SVENIHGRDEVTYTVE----VK 571
G G E L +S++ SM + D +TC NI G + ++
Sbjct: 669 GEGEEWLLIHQLSNEPDAR-SM-EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 726
Query: 572 VPPQ--PPILAVVDSYADSLHLQWSD----QGDGGSPILGYVINYKREHGDWEELQ---V 622
PP P +++ + SL L+W + +G +GY I Y R G + L
Sbjct: 727 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ 786
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKH-SQMITLN 680
+ ++ + +L T Y++ + AFN IG+G V T+ +VP P + S + T +
Sbjct: 787 DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTS 846
Query: 681 TTTVTVWLD-SWGDGGCGILYFVIEYREM---SQPQWRLVSNSVQATERVFSVSGLTPAA 736
++ + W + D +L + + Y+E +QP++ LV + + R ++GL
Sbjct: 847 SSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN---SSRSAQLTGLGKYV 903
Query: 737 HYQLRITAHNNAG 749
Y++++ A G
Sbjct: 904 LYEVQVLAFTRIG 916
Score = 173 bits (421), Expect = 3e-42
Identities = 122/428 (28%), Positives = 194/428 (45%), Gaps = 15/428 (3%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
Q P P ++ D ++R++ +SW G SP+ Y +Q +E P W V +
Sbjct: 1034 QPPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWAL--HSASVSHN 1090
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+S V L+P TSY R+ A N +G SE S+ + +TT + P P + V ++T
Sbjct: 1091 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1150
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQEL---NSNSTVLIASGPGGASYTVRTVEGAGTARS 242
+++ W+PP D NG +LG+ + ++EL +L GA++ T + S
Sbjct: 1151 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFMLRGINNPGATWAELTSMYSMRNLS 1210
Query: 243 RTTLS-----GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSS 297
R +L+ L KH Y + + YN+ E VP+ P + + ++
Sbjct: 1211 RPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATA 1270
Query: 298 QSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS 357
+ V+WEPPP+ +NG +QGY++ + E T ++ L L YT Y
Sbjct: 1271 TQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYM 1330
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
V+V AF AAGDG R+ P T++ PSAP+ +K + + + VSW P PNG+L GY
Sbjct: 1331 VSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGY 1390
Query: 418 TLYMSVIE--DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT 475
L DG + + S L + T++F + A T E VT
Sbjct: 1391 RLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVT 1450
Query: 476 VLPSDSVP 483
P + P
Sbjct: 1451 TGPGEGAP 1458
Score = 142 bits (345), Expect = 5e-33
Identities = 111/417 (26%), Positives = 179/417 (42%), Gaps = 23/417 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP----ESWPSTPQKVIV 123
++P P N+ + + R++ + + Y G + I ++V+ + E W Q
Sbjct: 624 ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 683
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKS 182
P + S V +L P T Y R+ N +G S PSQP + + T + P P +V + S
Sbjct: 684 PDA-RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 742
Query: 183 STELIVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
T L + W P +NGN +GY + + + + L S+ V+
Sbjct: 743 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL--------SHVVQD-----RV 789
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
T+ L++ Y V VQA+N+ E VPS P + A +S S+
Sbjct: 790 ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 849
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
V W P RNG++ GY+V Y + + S L+GL +Y Y V V
Sbjct: 850 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 909
Query: 361 CAFTAAGDGVRA-APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
AFT GDG + P+ T +DVP P I + + W PP++PNG+++ Y +
Sbjct: 910 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI 969
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
+ T +L+PS + + P + + F ++A TR G GEA + V
Sbjct: 970 THRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1025
Score = 126 bits (303), Expect = 6e-28
Identities = 168/720 (23%), Positives = 281/720 (39%), Gaps = 55/720 (7%)
Query: 64 SLSHQVPEMP-KNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQ- 119
SL + P P +N+ + +++I I W P N + YI++Y A P Q
Sbjct: 317 SLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLA--GLPVGYQF 374
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
K I V + +++L T+Y + + A N G S V T + VP+ PP +V E
Sbjct: 375 KNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 434
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
A +ST + TW P NG GY + E V + + ++
Sbjct: 435 ATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHV------ 488
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
+SGL+K Y V + + EDVP P G L + + S
Sbjct: 489 ----GFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTS 543
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYS 357
++VSW+ P + NGIL GYR+++ ++ VT + L ++GL T Y+
Sbjct: 544 LKVSWQEPGEK--NGILTGYRISWE---EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYT 598
Query: 358 VTVCAFTAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+ V A T+ G G V A+ + ++P P ++ + + + + P +
Sbjct: 599 IEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISR 658
Query: 417 YTL--YMSVIEDGREEGT-HKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EA 470
+ + + V+ +G E H+ P S E P + F + +G +
Sbjct: 659 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 718
Query: 471 TRVVTVL--PSDSVPARI---TSFSRNIVTPWKENISLSCN----KVGVPAPATTWTMNG 521
+R + L P D PA + T+ ++ W + N VG + +G
Sbjct: 719 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG 778
Query: 522 VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV----EVKVPPQPP 577
L ++ V D TI + N G + TV VP P
Sbjct: 779 KTLSHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 836
Query: 578 I-LAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHV-L 631
++ + + + S+ ++WS+ + D +LGY + YK + D + VE +S L
Sbjct: 837 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 896
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPC-DIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWLD 689
L Y++ + AF RIG G P + T VP P + TT+V +W
Sbjct: 897 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQP 956
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G IL + I +R + + + R ++ +GL P + Y RITA G
Sbjct: 957 PAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1015
Score = 95.5 bits (227), Expect = 9e-19
Identities = 128/629 (20%), Positives = 242/629 (38%), Gaps = 59/629 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P I + ++ ++++ W P A N I+ Y + ++ + + +V+ P S
Sbjct: 933 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAP-SAR 991
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS--STEL 186
+ L+P + Y RI A+ R G E ++ + VTT + PP V+ + + +
Sbjct: 992 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSV 1051
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+++WEP L + + YY T+ P G + + + + A S +
Sbjct: 1052 LLSWEPGSDGL---SPVRYY----------TIQTRELPSGR-WALHSASVSHNASS-FIV 1096
Query: 247 SGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ +Y V+A N ++ P P L ++ SV + W+
Sbjct: 1097 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQ 1156
Query: 306 PPPMRGRNGILQGYRVTYAPVT---------DWYGNEDAVTKQISGLHTT---------- 346
PP NGIL G+R+ Y + N A +++ +++
Sbjct: 1157 PPAEDKINGILLGFRIRYRELLYEGLRGFMLRGINNPGATWAELTSMYSMRNLSRPSLTQ 1216
Query: 347 --LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVS 403
L L ++ Y + + + A G+G + P E VP+A P ++ ++ ++ V+
Sbjct: 1217 YELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVT 1276
Query: 404 WLPP--SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
W PP S NG + GY +Y + G K + S + + V+A
Sbjct: 1277 WEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN-SVKLKNLTGYTAYMVSVAA 1335
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTW 517
G+G + + P+ +S + +T N+S N +
Sbjct: 1336 FNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYE 1395
Query: 518 TMNGV-GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN---IHGRD-EVTYTVEV-K 571
+ V G+ + +V + L + + A+ Y + +G + E T +
Sbjct: 1396 PCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGE 1455
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAGT 626
P PP + ++ Y+ ++ + WS G PI YVI + + G W+ ++ E +
Sbjct: 1456 GAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSS 1515
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L G Y + A N G G P
Sbjct: 1516 YTFSMDILKPGVSYDFRVIAVNDYGFGTP 1544
Score = 86.2 bits (204), Expect = 6e-16
Identities = 147/660 (22%), Positives = 255/660 (38%), Gaps = 61/660 (9%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++++SW +P N + Y + ++E + +T +P V L T+Y +
Sbjct: 543 SLKVSWQEPGEKNGILTGYRISWEEYNRT--NTRVTHYLPNVTLEYRVTGLTALTTYTIE 600
Query: 145 IIAENRLGQSEPS-QPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
+ A GQ + S + E+P GPP ++ + + + + P +I
Sbjct: 601 VAAMTSKGQGQVSASTISSGVPPELP-GPPTNLGISNIGPRSVTLQFRPGYDG--KTSIS 657
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
+ V Q + G G + + ARS + L Y+ ++ N
Sbjct: 658 RWLVEAQ--------VGVVGEGEEWLLIHQLSNEPDARSME-VPDLNPFTCYSFRMRQVN 708
Query: 264 SRXXXXXXX-XXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ--GYR 320
++ P + P + S S+ + W P P NG + GY+
Sbjct: 709 IVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYK 768
Query: 321 VTYAPVTDWYGNE-DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
+ Y+ +D +G V + T+ L +T Y V V AF A G G + V T
Sbjct: 769 IKYSR-SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRT 827
Query: 380 EEDVPSA-PADIKAAVSSRNKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM 436
E VPS+ P ++ A ++ + +LV W +P + NG+++GY + M +D + +
Sbjct: 828 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKV-MYKEKDSDTQPRFWLV 886
Query: 437 LSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFSRNIVT 495
S+ S + + ++ V A TR+G+G + + D VP I+
Sbjct: 887 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGP----PMGILF 942
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCS- 554
P E + S + P A + + + T R N ++ T T+ + + + YT +
Sbjct: 943 P--EVRTTSVRLIWQPPAAPNGII--LAYQITHRLNTTTANTATVEVL-APSARQYTATG 997
Query: 555 --VENIH--------------GRDEVTYTVEVKVPPQPPILAVV---DSYADSLHLQWSD 595
E+++ + + T E + PQPP +V D A S+ L W
Sbjct: 998 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP 1057
Query: 596 QGDGGSPILGYVINYKR-EHGDW--EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGT 652
DG SP+ Y I + G W V S ++ L T Y+ + A N IG
Sbjct: 1058 GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1117
Query: 653 GLPCDIVHAYTK-GTVPVKPKHSQMITLNTTTVTV--WLDSWGDGGCGILY-FVIEYREM 708
+ + T P + +T +TTT + W D GIL F I YRE+
Sbjct: 1118 SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYREL 1177
Score = 82.6 bits (195), Expect = 7e-15
Identities = 91/382 (23%), Positives = 159/382 (41%), Gaps = 40/382 (10%)
Query: 62 IGSLSHQVPEM-PKNIRVIDQQSRTIQISWTQ-PYAG-NSPIINYIVQYKEAPESWPSTP 118
+G VP P N+ + S ++ + W++ P A N ++ Y V YKE + P
Sbjct: 824 VGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQP 881
Query: 119 QKVIVPG-SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDV 176
+ +V G S SA + L Y ++++A R+G PS P+ T ++VP GPP +
Sbjct: 882 RFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGI 940
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+T + + W+PP NG IL Y + LN+ + TVE
Sbjct: 941 LFPEVRTTSVRLIWQPPAAP--NGIILAYQI-THRLNTTTA------------NTATVEV 985
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNA 294
+ + T +GL+ + Y + A + + PP +Q
Sbjct: 986 LAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQED 1045
Query: 295 LSSQSVRVSWEPPPMRGRNGI--LQGYRV--TYAPVTDWYGNEDAVTKQISGLHTTLSGL 350
+ ++SV +SWEP G +G+ ++ Y + P W + +V+ S + L
Sbjct: 1046 VRARSVLLSWEP----GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF--IVDRL 1099
Query: 351 RRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPS 408
+ +T+Y V A GD T + P AP + + +L+ W PP+
Sbjct: 1100 KPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPA 1159
Query: 409 SP--NGVLVGYTL-YMSVIEDG 427
NG+L+G+ + Y ++ +G
Sbjct: 1160 EDKINGILLGFRIRYRELLYEG 1181
Score = 71.3 bits (167), Expect = 2e-11
Identities = 60/244 (24%), Positives = 101/244 (41%), Gaps = 11/244 (4%)
Query: 517 WTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK-VP 573
W +G +G ES R + +G+L IS T S D G YTC V + G D + + V+ +P
Sbjct: 164 WEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 223
Query: 574 --PQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEH 629
P+ P+ + +++L W+ DG SP++ Y++ + W L V+ +
Sbjct: 224 HAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSV 283
Query: 630 VLPNLWCGTRYQLYITAFNRIGTG-LPCDIVHAYTKGTVPVKPKHSQMIT--LNTTTVTV 686
+ L YQ + A N +G G D P P + + + N + +
Sbjct: 284 TVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQ 343
Query: 687 WLDSWGDGGCGILY-FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W GIL ++I Y P N A + L +Y++ + A+
Sbjct: 344 WQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAY 403
Query: 746 NNAG 749
N+AG
Sbjct: 404 NSAG 407
Score = 58.4 bits (135), Expect = 1e-07
Identities = 80/320 (25%), Positives = 122/320 (38%), Gaps = 40/320 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGV 510
P T F A GE + + T L S+ IT + ++ L+C G
Sbjct: 5 PDDTGMFQCFARNAAGEVQTS---TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGA 61
Query: 511 PAPATTWTMN----GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
P PA TW G R G+L IS T +D+G YTC N G DE +
Sbjct: 62 PRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 121
Query: 567 TVEV----KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV 622
+ V ++ P +V+ S+ G P + I Y WE+
Sbjct: 122 DLVVWARTRITKPPQDQSVIKGTQASMVC-----GVTHDPRV--TIRY-----IWEKDGA 169
Query: 623 EAGTSEHVLPNLWCGTRYQLYI--TAFNRIGTGLPCDIVHAYTKGT---------VPVKP 671
GT H P + L+I T IGT C ++ A + +P P
Sbjct: 170 TLGTESH--PRIRLDRNGSLHISQTWSGDIGT-YTCRVISAGGNDSRSAHLRVRQLPHAP 226
Query: 672 KH--SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSV 729
+H + + T+ + + DG ++ +++E E + P W ++ SV +V
Sbjct: 227 EHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTV 285
Query: 730 SGLTPAAHYQLRITAHNNAG 749
GL PA YQ R+ A N+ G
Sbjct: 286 KGLVPARSYQFRLCAVNDVG 305
Score = 49.2 bits (112), Expect = 8e-05
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 7/183 (3%)
Query: 574 PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEA---GTSEH 629
P PP+ + + S+ L W IL Y I ++ VE ++
Sbjct: 934 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQY 993
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
L + Y ITA R G G + + T+ +P M+ L
Sbjct: 994 TATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 1053
Query: 690 SWGDGGCG---ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
SW G G + Y+ I+ RE+ +W L S SV F V L P Y+ R+ A N
Sbjct: 1054 SWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATN 1113
Query: 747 NAG 749
+ G
Sbjct: 1114 DIG 1116
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSAS 131
P + +I + S I I W+ G PI Y+++ + + E W + + S + S
Sbjct: 1460 PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1519
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
+ L+P SY R+IA N G PS P Q
Sbjct: 1520 MDILKPGVSYDFRVIAVNDYGFGTPSSPSQ 1549
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 198 bits (483), Expect = 9e-50
Identities = 188/733 (25%), Positives = 320/733 (43%), Gaps = 63/733 (8%)
Query: 53 DSKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPE 112
DS+ + LR+ L H PE P + + R I ++WT+P+ GNSP+I YI++ E
Sbjct: 255 DSR-SAHLRVRQLPH-APEHPV-ATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNA 311
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSG 171
W T V TS +V+ L PA SY R+ A N +G+ + S+ + V+ EE P+
Sbjct: 312 PW--TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTA 369
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
PPQ+V +++ +++ W+PP NG + GY + + +A P G Y
Sbjct: 370 PPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRY---------CLAGLPVG--YQF 418
Query: 232 RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQ 291
+ + A + L L Y + V AYNS ++ VP++PPG +
Sbjct: 419 KNITDADV--NNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVH 476
Query: 292 CNALSSQSVRVSWEPPPMRGRNGILQGYR-VTYAPVTDWYGNEDAVTKQIS-GLHTT-LS 348
A +S ++R +W P + NGI QGY+ + + P + +H +S
Sbjct: 477 AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVS 536
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
GL+++T Y +V FT GDG R+ P T EDVP + + + VSW P
Sbjct: 537 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 596
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
NG+L GY + TH L TL + + T+ V+A T G+G
Sbjct: 597 EKNGILTGYRISWEEYNRTNTRVTH--YLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQG 654
Query: 469 E--ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN------ 520
+ A+ + + +P + +P T+ + + P + G + W +
Sbjct: 655 QVSASTISSGVPPE-LPGPPTNLGISNIGPRSVTLQFRPGYDG-KTSISRWLVEAQVGVV 712
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTC-----SVENIHGRDEVTYTVE----VK 571
G G E L +S++ SM + D +TC NI G + ++
Sbjct: 713 GEGEEWLLIHQLSNEPDAR-SM-EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQ 770
Query: 572 VPPQ--PPILAVVDSYADSLHLQWSD----QGDGGSPILGYVINYKREHGDWEELQ---V 622
PP P +++ + SL L+W + +G +GY I Y R G + L
Sbjct: 771 APPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQ 830
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKH-SQMITLN 680
+ ++ + +L T Y++ + AFN IG+G V T+ +VP P + S + T +
Sbjct: 831 DRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTS 890
Query: 681 TTTVTVWLD-SWGDGGCGILYFVIEYREM---SQPQWRLVSNSVQATERVFSVSGLTPAA 736
++ + W + D +L + + Y+E +QP++ LV + + R ++GL
Sbjct: 891 SSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN---SSRSAQLTGLGKYV 947
Query: 737 HYQLRITAHNNAG 749
Y++++ A G
Sbjct: 948 LYEVQVLAFTRIG 960
Score = 173 bits (421), Expect = 3e-42
Identities = 121/430 (28%), Positives = 197/430 (45%), Gaps = 19/430 (4%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
Q P P ++ D ++R++ +SW G SP+ Y +Q +E P W V +
Sbjct: 1078 QPPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWAL--HSASVSHN 1134
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+S V L+P TSY R+ A N +G SE S+ + +TT + P P + V ++T
Sbjct: 1135 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 1194
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS----TVLIASGPGG------ASYTVRTVE 235
+++ W+PP D NG +LG+ + ++EL T+ + PG + Y++R +
Sbjct: 1195 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL- 1253
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
+ + ++ L L KH Y + + YN+ E VP+ P + +
Sbjct: 1254 -SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 1312
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTN 355
++ + V+WEPPP+ +NG +QGY++ + E T ++ L L YT
Sbjct: 1313 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTA 1372
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV 415
Y V+V AF AAGDG R+ P T++ PSAP+ +K + + + VSW P PNG+L
Sbjct: 1373 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 1432
Query: 416 GYTLYMSVIE--DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
GY L DG + + S L + T++F + A T E
Sbjct: 1433 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 1492
Query: 474 VTVLPSDSVP 483
VT P + P
Sbjct: 1493 VTTGPGEGAP 1502
Score = 142 bits (345), Expect = 5e-33
Identities = 111/417 (26%), Positives = 179/417 (42%), Gaps = 23/417 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP----ESWPSTPQKVIV 123
++P P N+ + + R++ + + Y G + I ++V+ + E W Q
Sbjct: 668 ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 727
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKS 182
P + S V +L P T Y R+ N +G S PSQP + + T + P P +V + S
Sbjct: 728 PDA-RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 786
Query: 183 STELIVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
T L + W P +NGN +GY + + + + L S+ V+
Sbjct: 787 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL--------SHVVQD-----RV 833
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
T+ L++ Y V VQA+N+ E VPS P + A +S S+
Sbjct: 834 ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 893
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
V W P RNG++ GY+V Y + + S L+GL +Y Y V V
Sbjct: 894 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 953
Query: 361 CAFTAAGDGVRA-APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
AFT GDG + P+ T +DVP P I + + W PP++PNG+++ Y +
Sbjct: 954 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI 1013
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
+ T +L+PS + + P + + F ++A TR G GEA + V
Sbjct: 1014 THRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 1069
Score = 126 bits (303), Expect = 6e-28
Identities = 168/720 (23%), Positives = 281/720 (39%), Gaps = 55/720 (7%)
Query: 64 SLSHQVPEMP-KNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQ- 119
SL + P P +N+ + +++I I W P N + YI++Y A P Q
Sbjct: 361 SLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLA--GLPVGYQF 418
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
K I V + +++L T+Y + + A N G S V T + VP+ PP +V E
Sbjct: 419 KNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 478
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
A +ST + TW P NG GY + E V + + ++
Sbjct: 479 ATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHV------ 532
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
+SGL+K Y V + + EDVP P G L + + S
Sbjct: 533 ----GFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTS 587
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYS 357
++VSW+ P + NGIL GYR+++ ++ VT + L ++GL T Y+
Sbjct: 588 LKVSWQEPGEK--NGILTGYRISWE---EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYT 642
Query: 358 VTVCAFTAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+ V A T+ G G V A+ + ++P P ++ + + + + P +
Sbjct: 643 IEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISR 702
Query: 417 YTL--YMSVIEDGREEGT-HKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EA 470
+ + + V+ +G E H+ P S E P + F + +G +
Sbjct: 703 WLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 762
Query: 471 TRVVTVL--PSDSVPARI---TSFSRNIVTPWKENISLSCN----KVGVPAPATTWTMNG 521
+R + L P D PA + T+ ++ W + N VG + +G
Sbjct: 763 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG 822
Query: 522 VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV----EVKVPPQPP 577
L ++ V D TI + N G + TV VP P
Sbjct: 823 KTLSHVVQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGP 880
Query: 578 I-LAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHV-L 631
++ + + + S+ ++WS+ + D +LGY + YK + D + VE +S L
Sbjct: 881 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 940
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPC-DIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWLD 689
L Y++ + AF RIG G P + T VP P + TT+V +W
Sbjct: 941 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQP 1000
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G IL + I +R + + + R ++ +GL P + Y RITA G
Sbjct: 1001 PAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1059
Score = 86.2 bits (204), Expect = 6e-16
Identities = 147/660 (22%), Positives = 255/660 (38%), Gaps = 61/660 (9%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++++SW +P N + Y + ++E + +T +P V L T+Y +
Sbjct: 587 SLKVSWQEPGEKNGILTGYRISWEEYNRT--NTRVTHYLPNVTLEYRVTGLTALTTYTIE 644
Query: 145 IIAENRLGQSEPS-QPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
+ A GQ + S + E+P GPP ++ + + + + P +I
Sbjct: 645 VAAMTSKGQGQVSASTISSGVPPELP-GPPTNLGISNIGPRSVTLQFRPGYDG--KTSIS 701
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
+ V Q + G G + + ARS + L Y+ ++ N
Sbjct: 702 RWLVEAQ--------VGVVGEGEEWLLIHQLSNEPDARSME-VPDLNPFTCYSFRMRQVN 752
Query: 264 SRXXXXXXX-XXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ--GYR 320
++ P + P + S S+ + W P P NG + GY+
Sbjct: 753 IVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYK 812
Query: 321 VTYAPVTDWYGNE-DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
+ Y+ +D +G V + T+ L +T Y V V AF A G G + V T
Sbjct: 813 IKYSR-SDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRT 871
Query: 380 EEDVPSA-PADIKAAVSSRNKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM 436
E VPS+ P ++ A ++ + +LV W +P + NG+++GY + M +D + +
Sbjct: 872 RESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKV-MYKEKDSDTQPRFWLV 930
Query: 437 LSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFSRNIVT 495
S+ S + + ++ V A TR+G+G + + D VP I+
Sbjct: 931 EGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGP----PMGILF 986
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCS- 554
P E + S + P A + + + T R N ++ T T+ + + + YT +
Sbjct: 987 P--EVRTTSVRLIWQPPAAPNGII--LAYQITHRLNTTTANTATVEVL-APSARQYTATG 1041
Query: 555 --VENIH--------------GRDEVTYTVEVKVPPQPPILAVV---DSYADSLHLQWSD 595
E+++ + + T E + PQPP +V D A S+ L W
Sbjct: 1042 LKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP 1101
Query: 596 QGDGGSPILGYVINYKR-EHGDW--EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGT 652
DG SP+ Y I + G W V S ++ L T Y+ + A N IG
Sbjct: 1102 GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGD 1161
Query: 653 GLPCDIVHAYTK-GTVPVKPKHSQMITLNTTTVTV--WLDSWGDGGCGILY-FVIEYREM 708
+ + T P + +T +TTT + W D GIL F I YRE+
Sbjct: 1162 SEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYREL 1221
Score = 83.0 bits (196), Expect = 5e-15
Identities = 93/394 (23%), Positives = 164/394 (41%), Gaps = 40/394 (10%)
Query: 62 IGSLSHQVPEM-PKNIRVIDQQSRTIQISWTQ-PYAG-NSPIINYIVQYKEAPESWPSTP 118
+G VP P N+ + S ++ + W++ P A N ++ Y V YKE + P
Sbjct: 868 VGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQP 925
Query: 119 QKVIVPG-SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDV 176
+ +V G S SA + L Y ++++A R+G PS P+ T ++VP GPP +
Sbjct: 926 RFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGI 984
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+T + + W+PP NG IL Y + LN+ + TVE
Sbjct: 985 LFPEVRTTSVRLIWQPPAAP--NGIILAYQI-THRLNTTTA------------NTATVEV 1029
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNA 294
+ + T +GL+ + Y + A + + PP +Q
Sbjct: 1030 LAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQED 1089
Query: 295 LSSQSVRVSWEPPPMRGRNGI--LQGYRV--TYAPVTDWYGNEDAVTKQISGLHTTLSGL 350
+ ++SV +SWEP G +G+ ++ Y + P W + +V+ S + L
Sbjct: 1090 VRARSVLLSWEP----GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF--IVDRL 1143
Query: 351 RRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPS 408
+ +T+Y V A GD T + P AP + + +L+ W PP+
Sbjct: 1144 KPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPA 1203
Query: 409 SP--NGVLVGYTL-YMSVIEDGREEGTHKRMLSP 439
NG+L+G+ + Y ++ +G T + + +P
Sbjct: 1204 EDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 1237
Score = 71.3 bits (167), Expect = 2e-11
Identities = 60/244 (24%), Positives = 101/244 (41%), Gaps = 11/244 (4%)
Query: 517 WTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK-VP 573
W +G +G ES R + +G+L IS T S D G YTC V + G D + + V+ +P
Sbjct: 208 WEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLP 267
Query: 574 --PQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEH 629
P+ P+ + +++L W+ DG SP++ Y++ + W L V+ +
Sbjct: 268 HAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSV 327
Query: 630 VLPNLWCGTRYQLYITAFNRIGTG-LPCDIVHAYTKGTVPVKPKHSQMIT--LNTTTVTV 686
+ L YQ + A N +G G D P P + + + N + +
Sbjct: 328 TVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQ 387
Query: 687 WLDSWGDGGCGILY-FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W GIL ++I Y P N A + L +Y++ + A+
Sbjct: 388 WQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAY 447
Query: 746 NNAG 749
N+AG
Sbjct: 448 NSAG 451
Score = 58.4 bits (135), Expect = 1e-07
Identities = 80/320 (25%), Positives = 122/320 (38%), Gaps = 40/320 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGV 510
P T F A GE + + T L S+ IT + ++ L+C G
Sbjct: 49 PDDTGMFQCFARNAAGEVQTS---TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGA 105
Query: 511 PAPATTWTMN----GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
P PA TW G R G+L IS T +D+G YTC N G DE +
Sbjct: 106 PRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASA 165
Query: 567 TVEV----KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV 622
+ V ++ P +V+ S+ G P + I Y WE+
Sbjct: 166 DLVVWARTRITKPPQDQSVIKGTQASMVC-----GVTHDPRV--TIRY-----IWEKDGA 213
Query: 623 EAGTSEHVLPNLWCGTRYQLYI--TAFNRIGTGLPCDIVHAYTKGT---------VPVKP 671
GT H P + L+I T IGT C ++ A + +P P
Sbjct: 214 TLGTESH--PRIRLDRNGSLHISQTWSGDIGT-YTCRVISAGGNDSRSAHLRVRQLPHAP 270
Query: 672 KH--SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSV 729
+H + + T+ + + DG ++ +++E E + P W ++ SV +V
Sbjct: 271 EHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAP-WTVLLASVDPKATSVTV 329
Query: 730 SGLTPAAHYQLRITAHNNAG 749
GL PA YQ R+ A N+ G
Sbjct: 330 KGLVPARSYQFRLCAVNDVG 349
Score = 49.2 bits (112), Expect = 8e-05
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 7/183 (3%)
Query: 574 PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEA---GTSEH 629
P PP+ + + S+ L W IL Y I ++ VE ++
Sbjct: 978 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQY 1037
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
L + Y ITA R G G + + T+ +P M+ L
Sbjct: 1038 TATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 1097
Query: 690 SWGDGGCG---ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
SW G G + Y+ I+ RE+ +W L S SV F V L P Y+ R+ A N
Sbjct: 1098 SWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATN 1157
Query: 747 NAG 749
+ G
Sbjct: 1158 DIG 1160
Score = 39.1 bits (87), Expect = 0.086
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ + C GVP P+ TW + V +E R +DG L IS D+G + C N
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNA 62
Query: 559 HGRDEV-TYTVEVKVPP 574
G + TY + P
Sbjct: 63 AGEVQTSTYLAVTSIAP 79
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 181 bits (440), Expect = 1e-44
Identities = 172/721 (23%), Positives = 307/721 (42%), Gaps = 59/721 (8%)
Query: 68 QVPEMPKNIRVIDQQSRT--IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
++P P+N+ V S + + +SW +P+ GNSPI+ YIV+ E W V
Sbjct: 666 ELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENSSPWKVHLSNV--GP 723
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVTTTEEVPSGPPQDVRVEAKSST 184
+T +V L PA +Y R+ A N +G+ + S + ++ EE PS PP+++ +++
Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQ 783
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++V W+PP NG + GY + ++ +A PG Y R + +
Sbjct: 784 SIMVQWQPPPETEHNGVLRGYILRYR---------LAGLPG--EYQQRNITSPEV--NYC 830
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++ L Y + V AYN ++ VP+ PP +Q A++S +++ W
Sbjct: 831 LVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLW 890
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYG-NEDAVTKQISGLHTT-LSGLRRYTNYSVTVCA 362
PPP + NGI QGY++ P + G+H ++ L+++T Y +V
Sbjct: 891 NPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLC 950
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
FT GDG + P T+ED P A + + VSW P NG++ GY +
Sbjct: 951 FTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE 1010
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT--RVVTVLPSD 480
V GR + L+ +T ++ T+ V+A T +G G T + + +P D
Sbjct: 1011 VY--GRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPD 1068
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLES---TLRKNVS 533
+P ++ + ++P + G + W + G +G E TL + +
Sbjct: 1069 -LPGAPSNLVISNISPRSATLQFRPGYDG-KTSISRWIVEGQVGAIGDEEEWVTLYEEEN 1126
Query: 534 SDGTLTISMTQSADSGNYTCSVE--NIHGRDEVTYTVEV----KVPPQ--PPILAVVDSY 585
+ + +Y ++ NI G + + V + PP P + V +
Sbjct: 1127 EPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTAS 1186
Query: 586 ADSLHLQW----SDQGDGGSPILGYVINYKR---EHGDWEELQVEAGTSEHVLPNLWCGT 638
SL L+W Q +G +GY I Y R + ++ + E + L
Sbjct: 1187 ETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWM 1246
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WLDSWGDGGC 696
Y+L + AFN +G G ++V T+ +VP P++ +++T + + W
Sbjct: 1247 EYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQN 1306
Query: 697 G-ILYFVIEYREMS---QPQWRLV-SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
G IL + I +R +P+ +V N Q+ ++GL Y+L++ A G+
Sbjct: 1307 GLILGYKILFRAKDLDPEPRSHIVRGNHTQSA----LLAGLRKFVLYELQVLAFTRIGNG 1362
Query: 752 L 752
+
Sbjct: 1363 V 1363
Score = 163 bits (395), Expect = 4e-39
Identities = 101/362 (27%), Positives = 173/362 (47%), Gaps = 17/362 (4%)
Query: 70 PEMPKNIRVIDQQ--SRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
P P+ + V + +R++++ W G SPI + +Q +E P W + +
Sbjct: 1477 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSI--SHE 1534
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
T+ V L+P TSY LR+ A N +G S+ S + VTT ++VP PP V +++
Sbjct: 1535 ATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSS 1594
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELN----SNSTVLIASGPGG------ASYTVRTVE 235
+++ W+PP+ + NG + GY + ++EL S + P A + +TV
Sbjct: 1595 VLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALXAELTAQSSFKTVN 1654
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
+ T+ + L+ L+K+ Y V++ AYN E P++ P +Q L
Sbjct: 1655 SSSTS-TMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTN 355
++ + V+W+PPP +NG +QGY++ Y E + L L +T
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTK 1773
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV 415
Y V++ AF AAGDG ++ P T + P AP+ + + + + VSW P++ NG+L
Sbjct: 1774 YLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQ 1833
Query: 416 GY 417
GY
Sbjct: 1834 GY 1835
Score = 121 bits (291), Expect = 2e-26
Identities = 169/713 (23%), Positives = 276/713 (38%), Gaps = 61/713 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
PKNI + +++I + W P N + YI++Y+ A + + P V
Sbjct: 772 PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSP-EVNYC 830
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
V +L T Y +++ A N G S+ V T + VP+ PPQ+V+ EA +ST + W
Sbjct: 831 LVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLW 890
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG +N +L + TV T+ ++ L+
Sbjct: 891 NPPPQQFING-----------INQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLK 939
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
K AY V + + ED P G L + S++VSW+ P
Sbjct: 940 KFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAV-GHLSFTEILDTSLKVSWQEP--L 996
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDA-VTKQI-SGLHT-TLSGLRRYTNYSVTVCAFTAAG 367
+NGI+ GY++++ + YG D+ +T + S H + GL T Y++ V A TA G
Sbjct: 997 EKNGIITGYQISW----EVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVG 1052
Query: 368 DG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
G V ++ + D+P AP+++ + S + + P + + + V
Sbjct: 1053 TGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAI 1112
Query: 427 GREEG---THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
G EE ++ P E P ++F + +G + V+ + P
Sbjct: 1113 GDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAP 1172
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN--GVG---------LESTLRKNV 532
+ S + T + ++ L VP P + + N VG L+S+ V
Sbjct: 1173 PDVAPTSVTVRTASETSLRLRW----VPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQV 1228
Query: 533 SSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSL 589
SD TI + N G + V + P A + A+++
Sbjct: 1229 VSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAV 1288
Query: 590 H-----LQWSD--QGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTR--- 639
L W+ + D ILGY I ++ + D E + H L G R
Sbjct: 1289 SSTQILLTWTSVPEQDQNGLILGYKILFRAKDLD-PEPRSHIVRGNHTQSALLAGLRKFV 1347
Query: 640 -YQLYITAFNRIGTGLP-CDIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWLDSWGDGGC 696
Y+L + AF RIG G+P ++ TK P P + T+V VW G
Sbjct: 1348 LYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI 1407
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
IL + I YR S + V AT R F+ + L P + Y R++A G
Sbjct: 1408 -ILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQG 1459
Score = 114 bits (274), Expect = 2e-24
Identities = 178/730 (24%), Positives = 295/730 (40%), Gaps = 83/730 (11%)
Query: 73 PKNIRVIDQQSRTIQISWT----QPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P ++ V ++++ W Y GN + Y ++Y + + S +V+
Sbjct: 1177 PTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRS-DLQSSAVAQVVSDRLER 1235
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++ L+ Y L++ A N +G S+ V+ T E VPS P++V EA SST++++
Sbjct: 1236 EFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILL 1295
Query: 189 TW-EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
TW P++D NG ILGY + F+ + + P S+ VR G L+
Sbjct: 1296 TWTSVPEQD-QNGLILGYKILFRAKDLD--------PEPRSHIVR-----GNHTQSALLA 1341
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
GL+K Y + V A+ +D PP L + SVR+ W+PP
Sbjct: 1342 GLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPP 1401
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
NGI+ GY++ Y + V + T + L + Y + A T G
Sbjct: 1402 --EEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQG 1459
Query: 368 DGVRAAPVYCHTEE-DVPSAPADI---KAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
G TE+ + P+ P ++ +A V++R+ + + W+P S + +T+ +
Sbjct: 1460 WGEPLEATVITTEKRERPAPPRELLVPQAEVTARS-LRLQWVPGSDGASPIRYFTMQVRE 1518
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE---ATRVVTVL--- 477
+ G E T+ +S + R P +++ + A+ +G+ + T VT L
Sbjct: 1519 LPRG-EWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDV 1577
Query: 478 ---PSDSVPARITSFSRNIVTPWKENISLSCN---------------KVGVPAPATTWTM 519
P SV A + S +++ W+ S N + G A T
Sbjct: 1578 PGEPPGSVSATPHTTS-SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKT-LK 1635
Query: 520 NGVGLESTLR-----KNVSSDGTLTI-SMTQSADSGNY--TCSVENIHGRDEVTYTVEVK 571
N + L + L K V+S T T+ +T Y + NI G + VEV
Sbjct: 1636 NPIALXAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVF 1695
Query: 572 VPPQPPILA-----VVDSYADSLHLQWS---DQGDGGSPILGYVINY--KREHGDWEELQ 621
V P +A V A L + W + G+ I GY I Y + E+++
Sbjct: 1696 VGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGN-IQGYKIYYWEADSQNETEKMK 1754
Query: 622 VEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
V V L NL T+Y + I+AFN G G D T P P +
Sbjct: 1755 VLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEIT 1814
Query: 681 TTTVTVWLDSWGDGGC--GILY-FVIEYREMSQPQW--RLVSNSVQAT-ERVFSVSGLTP 734
+TT+ V SWG+ GIL + + Y ++ Q ++V+ V+ +R V LT
Sbjct: 1815 STTLNV---SWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTK 1871
Query: 735 AAHYQLRITA 744
Y R+ A
Sbjct: 1872 GVTYFFRVQA 1881
Score = 109 bits (262), Expect = 5e-23
Identities = 144/633 (22%), Positives = 249/633 (39%), Gaps = 68/633 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P P + + + +++I W P N I+ Y + Y+ A S P T V V +V
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSS-PHTFTTVEVGATVRQ 1436
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST--ELI 187
+ +L P ++Y R+ A+ R G EP + +TT + PP+++ V T L
Sbjct: 1437 FTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLR 1496
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT-VEGAGTARSRTTL 246
+ W P + + Y+ T+ + P G T + + TA +
Sbjct: 1497 LQWVPGSD---GASPIRYF----------TMQVRELPRGEWQTYSSSISHEATA---CVV 1540
Query: 247 SGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ +Y + ++A N ++DVP PPG++ ++ SV + W+
Sbjct: 1541 DRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQ 1600
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGN-EDAVT-----------------KQISGLHTT- 346
PP NG+LQGYR+ Y + G+ +A T K ++ T+
Sbjct: 1601 PPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALXAELTAQSSFKTVNSSSTST 1660
Query: 347 ---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILV 402
L+ L++Y Y V + A+ G+ +APV E P+ AP +++ + +++ V
Sbjct: 1661 MCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEV 1720
Query: 403 SW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
+W PP S NG + GY +Y + E K + P + + + + +S
Sbjct: 1721 TWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS-HTKYLVSIS 1779
Query: 461 ASTRLGEGEAT--------RVVTVLPSDSVPARITSFSRNIV--TPWKENISLSCNKVGV 510
A G+G + + PS + ITS + N+ P N L +V V
Sbjct: 1780 AFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRV-V 1838
Query: 511 PAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
P + GV T+ + L + + + I E+ +
Sbjct: 1839 YEPLAP--VQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITA 1896
Query: 571 ---KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQV 622
+ P P +V A L LQW++ G +P GYVI + + G W+ ++
Sbjct: 1897 GPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPR 1956
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
A + L L G Y+ + A N G G P
Sbjct: 1957 SATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEP 1989
Score = 102 bits (244), Expect = 8e-21
Identities = 94/365 (25%), Positives = 151/365 (41%), Gaps = 30/365 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T + +L+ Y + + A N +G+S S PV+V E P+ PQ+V+V ++++L
Sbjct: 1660 TMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLE 1719
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
VTW+PP + NGNI GY + + E +S + ++ L
Sbjct: 1720 VTWDPPPPESQNGNIQGYKIYYWEADSQNET-------------EKMKVLFLPEPVVRLK 1766
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L H Y V + A+N+ + P P L + ++S ++ VSW P
Sbjct: 1767 NLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAP-SFLAFSEITSTTLNVSWGEP 1825
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---LHTTLSGLRRYTNYSVTVCAFT 364
NGILQGYRV Y P+ G VT ++ G + L + Y V A T
Sbjct: 1826 A--AANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQART 1883
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
A + E P +P D+ S +++ + W S + GY +
Sbjct: 1884 ITYGPELQANITAGPAEGSPGSPRDV-LVTKSASELTLQWTEGHSGDTPTTGYVIEARPS 1942
Query: 425 EDGREEGTHK---RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++G + K R + TLS + R T++F V A G GE + PS +
Sbjct: 1943 DEGLWDMFVKDIPRSATSYTLSLDKLRQ--GVTYEFRVVAVNEAGYGEPSN-----PSTA 1995
Query: 482 VPARI 486
V A++
Sbjct: 1996 VSAQV 2000
Score = 97.5 bits (232), Expect = 2e-19
Identities = 99/394 (25%), Positives = 167/394 (42%), Gaps = 30/394 (7%)
Query: 63 GSLSHQVPEM-PKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQ 119
G VP P+N+ S I ++WT N I+ Y + ++ A + P P+
Sbjct: 1269 GRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFR-AKDLDPE-PR 1326
Query: 120 KVIVPGSVT-SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
IV G+ T SA + L+ Y L+++A R+G PS P+ + T++ GPP +
Sbjct: 1327 SHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVF 1386
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
T + + W+PP+ NG ILGY + ++ L +S P +T TVE
Sbjct: 1387 PEVRLTSVRIVWQPPEEP--NGIILGYQIAYR--------LASSSP----HTFTTVEVGA 1432
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA--LS 296
T R + T + L +AY + A + + PP L ++
Sbjct: 1433 TVR-QFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVT 1491
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
++S+R+ W P +V P +W +++ + + + LR +T+Y
Sbjct: 1492 ARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATAC--VVDRLRPFTSY 1549
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAP-ADIKAAVSSRNKILVSWLPP--SSPNG 412
+ + A GD ++ T +DVP P + A + + +L+ W PP S NG
Sbjct: 1550 KLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNG 1609
Query: 413 VLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHE 445
+L GY +Y +E GT K + +P L E
Sbjct: 1610 LLQGYRIYYRELEYEAGSGTEAKTLKNPIALXAE 1643
Score = 83.4 bits (197), Expect = 4e-15
Identities = 113/456 (24%), Positives = 186/456 (40%), Gaps = 37/456 (8%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ--GYRVTYAPVTDWYGN--EDAVTK 338
P + P ++ S S+R+ W P P NG + GYR+ Y W + AV +
Sbjct: 1173 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKY-----WRSDLQSSAVAQ 1227
Query: 339 QISG---LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAV 394
+S T+ L + Y + + AF A G G + V T E VPS AP ++ A
Sbjct: 1228 VVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEA 1287
Query: 395 SSRNKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR 452
S +IL++W +P NG+++GY + + E +H + T S +
Sbjct: 1288 VSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSH-IVRGNHTQSALLAGLRKF 1346
Query: 453 ATHQFWVSASTRLGEG-EATRVVTVLPSDSVP----------ARITSFSRNIVTPWKE-- 499
++ V A TR+G G +T ++ D P R+TS R + P +E
Sbjct: 1347 VLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSV-RIVWQPPEEPN 1405
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
I L A ++ T V + +T+R+ ++D + + E +
Sbjct: 1406 GIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLE 1465
Query: 560 GRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWE 618
T E PP+ ++ + A SL LQW DG SPI + + + G+W+
Sbjct: 1466 ATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQ 1525
Query: 619 --ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQ 675
+ + V+ L T Y+L + A N IG + + T VP +P S
Sbjct: 1526 TYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSV 1585
Query: 676 MITLNTTTVTV--WLDSWGDGGCGILY-FVIEYREM 708
T +TT+ + W + G+L + I YRE+
Sbjct: 1586 SATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYREL 1621
Score = 68.5 bits (160), Expect = 1e-10
Identities = 61/244 (25%), Positives = 100/244 (40%), Gaps = 11/244 (4%)
Query: 517 WTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV-KVP 573
W + V L ST R V DG+L IS T S D G+Y+C + + G D +EV ++P
Sbjct: 609 WKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELP 668
Query: 574 --PQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAG--TSEH 629
PQ +++ S++ ++ L W DG SPIL Y++ W+ G +
Sbjct: 669 HSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENSSPWKVHLSNVGPEMTGV 728
Query: 630 VLPNLWCGTRYQLYITAFNRIGTG-LPCDIVHAYTKGTVPVKPKHSQMIT--LNTTTVTV 686
+ L YQ + A N +G G + P P + + + N + +
Sbjct: 729 TVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQ 788
Query: 687 WLDSWGDGGCGILY-FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W G+L +++ YR P N V+ L Y++++ A+
Sbjct: 789 WQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAY 848
Query: 746 NNAG 749
N AG
Sbjct: 849 NGAG 852
Score = 56.8 bits (131), Expect = 4e-07
Identities = 67/261 (25%), Positives = 99/261 (37%), Gaps = 23/261 (8%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTL----RKNVSSDGTLTISMTQSADSGNYTCSVENI 558
L C G P PA TW L S R + G L I+ D+GNYTC N
Sbjct: 499 LRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANT 558
Query: 559 HGRDEVTYTVEV----KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREH 614
G + T+ V + P V+ +LH + + N
Sbjct: 559 EGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTP 618
Query: 615 GDWEELQVEAGTSEHVLPNLWCGT--RYQLYITA----FNRIGTGLPCDIVHAYTKGTVP 668
+ VE S ++ W G Y I + +R+ ++ H+ V
Sbjct: 619 SSTSRIVVEKDGS-LLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVS 677
Query: 669 VKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
HS + L+ W+ + DG ILY+++E E S P W++ ++V +
Sbjct: 678 PNSSHSHAVVLS------WVRPF-DGNSPILYYIVELSENSSP-WKVHLSNVGPEMTGVT 729
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
VSGLTPA YQ R+ A N G
Sbjct: 730 VSGLTPARTYQFRVCAVNEVG 750
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 9/184 (4%)
Query: 574 PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD---WEELQVEAGTSEH 629
P PP+ L + S+ + W + ILGY I Y+ + ++V A +
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQF 1437
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT-KGTVPVKPKHSQMITLNTTTVTVWL 688
+L + Y ++A R G G P + T K P P+ + T ++ L
Sbjct: 1438 TATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRL 1497
Query: 689 DSW---GDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W DG I YF ++ RE+ + +W+ S+S+ V L P Y+LR+ A
Sbjct: 1498 -QWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKAT 1556
Query: 746 NNAG 749
N+ G
Sbjct: 1557 NDIG 1560
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
P P+++ V S + + WT+ ++G++P Y+++ + + E W + + P S T
Sbjct: 1903 PGSPRDVLVTKSASE-LTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDI--PRSAT 1959
Query: 129 S--ASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEVP 169
S S+ L+ +Y R++A N G EPS P V+ E P
Sbjct: 1960 SYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 2003
Score = 38.3 bits (85), Expect = 0.15
Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 3/80 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLE--STLRKNVSSDGTLTISMTQSADSGNYTCSV 555
+E + + C +GVP P W + + + R V + G L I + DSG + C
Sbjct: 401 EETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFA 460
Query: 556 ENIHGRDEV-TYTVEVKVPP 574
N G + TY + P
Sbjct: 461 SNEGGEIQTHTYLDVTNIAP 480
>BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein.
Length = 1329
Score = 173 bits (422), Expect = 2e-42
Identities = 120/420 (28%), Positives = 191/420 (45%), Gaps = 18/420 (4%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
Q P P ++ D ++R++ +SW G SP+ Y +Q +E P W V +
Sbjct: 577 QPPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWAL--HSASVSHN 633
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+S V L+P TSY R+ A N +G SE S+ + +TT + P P + V ++T
Sbjct: 634 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 693
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+++ W+PP D NG +LG+ + ++EL + G G + +R + G + T
Sbjct: 694 VLIRWQPPAEDKINGILLGFRIRYREL-------LYEGLRG--FMLRGINNPGATWAELT 744
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L KH Y + + YN+ E VP+ P + + ++ + V+WE
Sbjct: 745 Y--LNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWE 802
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
PPP+ +NG +QGY++ + E T ++ L L YT Y V+V AF A
Sbjct: 803 PPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNA 862
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
AGDG R+ P T++ PSAP+ +K + + + VSW P PNG+L GY L
Sbjct: 863 AGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCS 922
Query: 426 --DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
DG + + S L + T++F + A T E VT P + P
Sbjct: 923 PVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAP 982
Score = 142 bits (345), Expect = 5e-33
Identities = 111/417 (26%), Positives = 179/417 (42%), Gaps = 23/417 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP----ESWPSTPQKVIV 123
++P P N+ + + R++ + + Y G + I ++V+ + E W Q
Sbjct: 167 ELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 226
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKS 182
P + S V +L P T Y R+ N +G S PSQP + + T + P P +V + S
Sbjct: 227 PDA-RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 285
Query: 183 STELIVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
T L + W P +NGN +GY + + + + L S+ V+
Sbjct: 286 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL--------SHVVQD-----RV 332
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
T+ L++ Y V VQA+N+ E VPS P + A +S S+
Sbjct: 333 ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 392
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
V W P RNG++ GY+V Y + + S L+GL +Y Y V V
Sbjct: 393 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQV 452
Query: 361 CAFTAAGDGVRA-APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
AFT GDG + P+ T +DVP P I + + W PP++PNG+++ Y +
Sbjct: 453 LAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI 512
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
+ T +L+PS + + P + + F ++A TR G GEA + V
Sbjct: 513 THRLNTTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVV 568
Score = 124 bits (298), Expect = 2e-27
Identities = 160/648 (24%), Positives = 263/648 (40%), Gaps = 51/648 (7%)
Query: 70 PEM-PKNIRVIDQQSRTIQISWT----QPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
P+M P N+ + ++ + W Y GN + Y ++Y + + T V+
Sbjct: 272 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS-DGHGKTLSHVVQD 330
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++++L+ T Y +++ A N +G SQ V T E VPS P +V A +S+
Sbjct: 331 RVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSS 390
Query: 185 ELIVTW-EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
++V W E P+ D NG +LGY V ++E +S++ VEG ++RS
Sbjct: 391 SMLVRWSEVPEADR-NGLVLGYKVMYKEKDSDTQPRFW-----------LVEG-NSSRS- 436
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXX-XXXXXMEDVPSLPPGALQCNALSSQSVRV 302
L+GL K+ Y V V A+ ++DVP P G L + + SVR+
Sbjct: 437 AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGIL-FPEVRTTSVRL 495
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W+PP NGI+ Y++T+ T S T +GL+ + Y + A
Sbjct: 496 IWQPPA--APNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITA 553
Query: 363 FTAAGDGVRAAPVYCHTEE----DVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
T G G A + TE+ PS P + V +R+ +L+SW P S + YT
Sbjct: 554 QTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYT 612
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE---ATRVVT 475
+ + GR H +S + S R P +++F V A+ +G+ E + +T
Sbjct: 613 IQTRELPSGRW-ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT 671
Query: 476 VLPS--DSVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK 530
L + D P ++ + +++ W+ N + + + GL + +
Sbjct: 672 TLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFMLR 731
Query: 531 NVSSDGTLTISMTQSADSGNYTC--SVENIHGRDEVTYTVEV----KVPPQPPILAVVD- 583
+++ G +T Y SV N G + EV VP P VV
Sbjct: 732 GINNPGATWAELTYLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHG 791
Query: 584 SYADSLHLQWSDQ--GDGGSPILGYVINY-KREHGDWEELQVEAGTSEHV--LPNLWCGT 638
+ A L + W I GY I + + + G+ E +E+ L NL T
Sbjct: 792 ATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYT 851
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV 686
Y + + AFN G G T+ P P + L TT+V V
Sbjct: 852 AYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 899
Score = 106 bits (255), Expect = 4e-22
Identities = 129/611 (21%), Positives = 242/611 (39%), Gaps = 42/611 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P I + ++ ++++ W P A N I+ Y + ++ + + +V+ P S
Sbjct: 476 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAP-SAR 534
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS--STEL 186
+ L+P + Y RI A+ R G E ++ + VTT + PP V+ + + +
Sbjct: 535 QYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSV 594
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+++WEP L + + YY T+ P G + + + + A S +
Sbjct: 595 LLSWEPGSDGL---SPVRYY----------TIQTRELPSGR-WALHSASVSHNASS-FIV 639
Query: 247 SGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ +Y V+A N ++ P P L ++ SV + W+
Sbjct: 640 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQ 699
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTVCA 362
PP NGIL G+R+ Y + + G + + I+ T L+ L ++ Y + +
Sbjct: 700 PPAEDKINGILLGFRIRYRELL-YEGLRGFMLRGINNPGATWAELTYLNKHRRYEIRMSV 758
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPNGVLVGYTL 419
+ A G+G + P E VP+A P ++ ++ ++ V+W PP S NG + GY +
Sbjct: 759 YNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 818
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
Y + G K + S + + V+A G+G +
Sbjct: 819 YFWEAQRGNLTERVKTLFLAEN-SVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQ 877
Query: 480 DSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGV-GLESTLRKNVSS 534
+ P+ +S + +T N+S N + + V G+ + +V
Sbjct: 878 QAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKG 937
Query: 535 DGTLTISMTQSADSGNYTCSVEN---IHGRD-EVTYTVEV-KVPPQPPILAVVDSYADSL 589
+ L + + A+ Y + +G + E T + P PP + ++ Y+ ++
Sbjct: 938 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAI 997
Query: 590 HLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAGTSEHVLPNLWCGTRYQLYI 644
+ WS G PI YVI + + G W+ ++ E + + L G Y +
Sbjct: 998 AIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV 1057
Query: 645 TAFNRIGTGLP 655
A N G G P
Sbjct: 1058 IAVNDYGFGTP 1068
Score = 91.5 bits (217), Expect = 2e-17
Identities = 104/449 (23%), Positives = 186/449 (41%), Gaps = 43/449 (9%)
Query: 62 IGSLSHQVPEM-PKNIRVIDQQSRTIQISWTQ-PYAG-NSPIINYIVQYKEAPESWPSTP 118
+G VP P N+ + S ++ + W++ P A N ++ Y V YKE + P
Sbjct: 367 VGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD--TQP 424
Query: 119 QKVIVPG-SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDV 176
+ +V G S SA + L Y ++++A R+G PS P+ T ++VP GPP +
Sbjct: 425 RFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGI 483
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+T + + W+PP NG IL Y + LN+ + TVE
Sbjct: 484 LFPEVRTTSVRLIWQPPAAP--NGIILAYQI-THRLNTTTA------------NTATVEV 528
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNA 294
+ + T +GL+ + Y + A + + PP +Q
Sbjct: 529 LAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQED 588
Query: 295 LSSQSVRVSWEPPPMRGRNGI--LQGYRV--TYAPVTDWYGNEDAVTKQISGLHTTLSGL 350
+ ++SV +SWEP G +G+ ++ Y + P W + +V+ S + L
Sbjct: 589 VRARSVLLSWEP----GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF--IVDRL 642
Query: 351 RRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPS 408
+ +T+Y V A GD T + P AP + + +L+ W PP+
Sbjct: 643 KPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPA 702
Query: 409 SP--NGVLVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
NG+L+G+ + Y ++ +G + + +P E + ++ +S +
Sbjct: 703 EDKINGILLGFRIRYRELLYEGLRGFMLRGINNPGATWAELTYLNKHRRYEIRMSVYNAV 762
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIV 494
GEG ++ V ++VP T+ RN+V
Sbjct: 763 GEGPSSPPQEVFVGEAVP---TAAPRNVV 788
Score = 89.4 bits (212), Expect = 6e-17
Identities = 122/534 (22%), Positives = 208/534 (38%), Gaps = 39/534 (7%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SGL+K Y V + + EDVP P G L + + S++VSW+
Sbjct: 34 VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQ 92
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAF 363
P + NGIL GYR+++ ++ VT + L ++GL T Y++ V A
Sbjct: 93 EPGEK--NGILTGYRISWE---EYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAM 147
Query: 364 TAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL--Y 420
T+ G G V A+ + ++P P ++ + + + + P + + +
Sbjct: 148 TSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQ 207
Query: 421 MSVIEDGRE-EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG---EGEATRVVTV 476
+ V+ +G E H+ P S E P + F + +G + +R +
Sbjct: 208 VGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQT 267
Query: 477 L--PSDSVPARI---TSFSRNIVTPWKENISLSCN----KVGVPAPATTWTMNGVGLEST 527
L P D PA + T+ ++ W + N VG + +G L
Sbjct: 268 LQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 327
Query: 528 LRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV----EVKVPPQPPI-LAVV 582
++ V D TI + N G + TV VP P ++ +
Sbjct: 328 VQDRVERD--YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSAL 385
Query: 583 DSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDWEE--LQVEAGTSEHV-LPNLWCG 637
+ + S+ ++WS+ + D +LGY + YK + D + VE +S L L
Sbjct: 386 ATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKY 445
Query: 638 TRYQLYITAFNRIGTGLPC-DIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWLDSWGDGG 695
Y++ + AF RIG G P + T VP P + TT+V +W G
Sbjct: 446 VLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNG 505
Query: 696 CGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
IL + I +R + + + R ++ +GL P + Y RITA G
Sbjct: 506 I-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 558
Score = 49.2 bits (112), Expect = 8e-05
Identities = 46/183 (25%), Positives = 68/183 (37%), Gaps = 7/183 (3%)
Query: 574 PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEA---GTSEH 629
P PP+ + + S+ L W IL Y I ++ VE ++
Sbjct: 477 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQY 536
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
L + Y ITA R G G + + T+ +P M+ L
Sbjct: 537 TATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 596
Query: 690 SWGDGGCG---ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
SW G G + Y+ I+ RE+ +W L S SV F V L P Y+ R+ A N
Sbjct: 597 SWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATN 656
Query: 747 NAG 749
+ G
Sbjct: 657 DIG 659
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSAS 131
P + +I + S I I W+ G PI Y+++ + + E W + + S + S
Sbjct: 984 PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 1043
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
+ L+P SY R+IA N G PS P Q
Sbjct: 1044 MDILKPGVSYDFRVIAVNDYGFGTPSSPSQ 1073
Score = 43.6 bits (98), Expect = 0.004
Identities = 81/369 (21%), Positives = 129/369 (34%), Gaps = 30/369 (8%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S+ V L+ T Y ++ G S P V T E+VP GP + T
Sbjct: 28 SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVP-GPVGHLSFSEILDTS 86
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L V+W+ P NG + GY + ++E N +T + P T R T
Sbjct: 87 LKVSWQEPGEK--NGILTGYRISWEEYNRTNTRVTHYLPN------------VTLEYRVT 132
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
GL Y + V A S+ + PP L + + +SV + +
Sbjct: 133 --GLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR 190
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS----GLRRYTNYSVTVC 361
P G+ I + V G E + Q+S S L +T YS +
Sbjct: 191 -PGYDGKTSISRWLVEAQVGVVG-EGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMR 248
Query: 362 AFTAAGDGVRAAPV-YCHTEEDVPS-APADIKAAVSSRNKILVSWLP-PS---SPNGVLV 415
G + P T + P APA++ +S + + W+P P + N V
Sbjct: 249 QVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV 308
Query: 416 GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT 475
GY + S DG + + + ++ V A +G G ++ V
Sbjct: 309 GYKIKYS-RSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVV 367
Query: 476 VLPSDSVPA 484
+SVP+
Sbjct: 368 GRTRESVPS 376
>AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein
protein.
Length = 1185
Score = 173 bits (421), Expect = 3e-42
Identities = 121/430 (28%), Positives = 197/430 (45%), Gaps = 19/430 (4%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
Q P P ++ D ++R++ +SW G SP+ Y +Q +E P W V +
Sbjct: 370 QPPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWAL--HSASVSHN 426
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+S V L+P TSY R+ A N +G SE S+ + +TT + P P + V ++T
Sbjct: 427 ASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTS 486
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS----TVLIASGPGG------ASYTVRTVE 235
+++ W+PP D NG +LG+ + ++EL T+ + PG + Y++R +
Sbjct: 487 VLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL- 545
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
+ + ++ L L KH Y + + YN+ E VP+ P + +
Sbjct: 546 -SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGA 604
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTN 355
++ + V+WEPPP+ +NG +QGY++ + E T ++ L L YT
Sbjct: 605 TATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTA 664
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV 415
Y V+V AF AAGDG R+ P T++ PSAP+ +K + + + VSW P PNG+L
Sbjct: 665 YMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILE 724
Query: 416 GYTLYMSVIE--DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
GY L DG + + S L + T++F + A T E
Sbjct: 725 GYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEAN 784
Query: 474 VTVLPSDSVP 483
VT P + P
Sbjct: 785 VTTGPGEGAP 794
Score = 128 bits (308), Expect = 1e-28
Identities = 97/352 (27%), Positives = 150/352 (42%), Gaps = 18/352 (5%)
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTELI 187
S V +L P T Y R+ N +G S PSQP + + T + P P +V + S T L
Sbjct: 24 SMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLW 83
Query: 188 VTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ W P +NGN +GY + + + + L S+ V+ T
Sbjct: 84 LRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTL--------SHVVQD-----RVERDYT 130
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ L++ Y V VQA+N+ E VPS P + A +S S+ W
Sbjct: 131 IEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLGRWS 190
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P RNG++ GY+V Y + + S L+GL +Y Y V V AFT
Sbjct: 191 EVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTR 250
Query: 366 AGDGVRA-APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
GDG + P+ T +DVP P I + + W PP++PNG+++ Y + +
Sbjct: 251 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLN 310
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
T +L+PS + + P + + F ++A TR GEA + V
Sbjct: 311 TTTANTAT-VEVLAPSARQYTATGLKPESVYLFRITAQTRKVWGEAAEALVV 361
Score = 107 bits (257), Expect = 2e-22
Identities = 158/667 (23%), Positives = 263/667 (39%), Gaps = 70/667 (10%)
Query: 70 PEM-PKNIRVIDQQSRTIQISWT----QPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
P+M P N+ + ++ + W Y GN + Y ++Y + + T V+
Sbjct: 65 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRS-DGHGKTLSHVVQD 123
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
++++L+ T Y +++ A N +G SQ V T E VPS P +V A +S+
Sbjct: 124 RVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSS 183
Query: 185 ELIVTW-EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
++ W E P+ D NG +LGY V ++E +S++ VEG ++RS
Sbjct: 184 SMLGRWSEVPEADR-NGLVLGYKVMYKEKDSDT-----------QPRFWLVEG-NSSRS- 229
Query: 244 TTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRV 302
L+GL K+ Y V V A+ ++DVP PP + + + SVR+
Sbjct: 230 AQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVRL 288
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W+PP NGI+ Y++T+ T S T +GL+ + Y + A
Sbjct: 289 IWQPP--AAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITA 346
Query: 363 FTAAGDGVRAAPVYCHTEE----DVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
T G A + TE+ PS P + V +R+ +L+SW P S + YT
Sbjct: 347 QTRKVWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYT 405
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE---GEATRVVT 475
+ + GR H +S + S R P +++F V A+ +G+ E + +T
Sbjct: 406 IQTRELPSGR-WALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT 464
Query: 476 VLPS--DSVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK 530
L + D P ++ + +++ W+ N + + + GL +
Sbjct: 465 TLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR 524
Query: 531 NVSSDGTLTISMTQSADSGN--------YTCSVENIHGRDEVTYTVEVKV------PPQ- 575
+++ G +T N Y N H R E+ +V V PPQ
Sbjct: 525 GINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQE 584
Query: 576 -----------PPILAVVDSYADSLHLQWSDQ--GDGGSPILGYVINY-KREHGDWEELQ 621
P + V + A L + W I GY I + + + G+ E
Sbjct: 585 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 644
Query: 622 VEAGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITL 679
+E+ L NL T Y + + AFN G G T+ P P + L
Sbjct: 645 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSEL 704
Query: 680 NTTTVTV 686
TT+V V
Sbjct: 705 TTTSVNV 711
Score = 91.9 bits (218), Expect = 1e-17
Identities = 127/629 (20%), Positives = 241/629 (38%), Gaps = 59/629 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P I + ++ ++++ W P A N I+ Y + ++ + + +V+ P S
Sbjct: 269 VPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAP-SAR 327
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS--STEL 186
+ L+P + Y RI A+ R E ++ + VTT + PP V+ + + +
Sbjct: 328 QYTATGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSV 387
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+++WEP L + + YY T+ P G + + + + A S +
Sbjct: 388 LLSWEPGSDGL---SPVRYY----------TIQTRELPSGR-WALHSASVSHNASS-FIV 432
Query: 247 SGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ +Y V+A N ++ P P L ++ SV + W+
Sbjct: 433 DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQ 492
Query: 306 PPPMRGRNGILQGYRVTYAPVT---------DWYGNEDAVTKQISGLHTT---------- 346
PP NGIL G+R+ Y + N A +++ +++
Sbjct: 493 PPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQ 552
Query: 347 --LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVS 403
L L ++ Y + + + A G+G + P E VP+A P ++ ++ ++ V+
Sbjct: 553 YELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVT 612
Query: 404 WLPP--SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
W PP S NG + GY +Y + G K + S + + V+A
Sbjct: 613 WEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAEN-SVKLKNLTGYTAYMVSVAA 671
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTW 517
G+G + + P+ +S + +T N+S N +
Sbjct: 672 FNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYE 731
Query: 518 TMNGV-GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN---IHGRD-EVTYTVEV-K 571
+ V G+ + +V + L + + A+ Y + +G + E T +
Sbjct: 732 PCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGE 791
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAGT 626
P PP + ++ Y+ ++ + WS G PI YVI + + G W+ ++ E +
Sbjct: 792 GAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSS 851
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L G Y + A N G G P
Sbjct: 852 YTFSMDILKPGVSYDFRVIAVNDYGFGTP 880
Score = 80.6 bits (190), Expect = 3e-14
Identities = 115/459 (25%), Positives = 183/459 (39%), Gaps = 43/459 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ--GYRVTYAPVTDWYGNE-DAVTKQ 339
P + P + S S+ + W P P NG + GY++ Y+ +D +G V +
Sbjct: 65 PDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSR-SDGHGKTLSHVVQD 123
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRN 398
T+ L +T Y V V AF A G G + V T E VPS+ P ++ A ++ +
Sbjct: 124 RVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSS 183
Query: 399 KILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+L W +P + NG+++GY + M +D + + S+ S + + ++
Sbjct: 184 SMLGRWSEVPEADRNGLVLGYKV-MYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYE 242
Query: 457 FWVSASTRLGEGEATRV-VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
V A TR+G+G + + D VP I+ P E + S + P A
Sbjct: 243 VQVLAFTRIGDGSPSHPPILERTLDDVPGP----PMGILFP--EVRTTSVRLIWQPPAAP 296
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTI-----SMTQSADSG---------NYTCSVENIHGR 561
+ + + T R N ++ T T+ S Q +G T + G
Sbjct: 297 NGII--LAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKVWGE 354
Query: 562 --DEVTYTVEVKVPPQPPILAVV---DSYADSLHLQWSDQGDGGSPILGYVINYKR-EHG 615
+ + T E + PQPP +V D A S+ L W DG SP+ Y I + G
Sbjct: 355 AAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSG 414
Query: 616 DW--EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK-GTVPVKPK 672
W V S ++ L T Y+ + A N IG + + T P +
Sbjct: 415 RWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAP 474
Query: 673 HSQMITLNTTTVTV--WLDSWGDGGCGILY-FVIEYREM 708
+T +TTT + W D GIL F I YRE+
Sbjct: 475 TILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYREL 513
Score = 80.2 bits (189), Expect = 4e-14
Identities = 93/394 (23%), Positives = 163/394 (41%), Gaps = 40/394 (10%)
Query: 62 IGSLSHQVPEM-PKNIRVIDQQSRTIQISWTQ-PYAG-NSPIINYIVQYKEAPESWPSTP 118
+G VP P N+ + S ++ W++ P A N ++ Y V YKE + P
Sbjct: 160 VGRTRESVPSSGPTNVSALATTSSSMLGRWSEVPEADRNGLVLGYKVMYKEKDSD--TQP 217
Query: 119 QKVIVPG-SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDV 176
+ +V G S SA + L Y ++++A R+G PS P+ T ++VP GPP +
Sbjct: 218 RFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGI 276
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+T + + W+PP NG IL Y + LN+ + TVE
Sbjct: 277 LFPEVRTTSVRLIWQPPAAP--NGIILAYQI-THRLNTTTA------------NTATVEV 321
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNA 294
+ + T +GL+ + Y + A + + PP +Q
Sbjct: 322 LAPSARQYTATGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRDRPQPPSRPMVQQED 381
Query: 295 LSSQSVRVSWEPPPMRGRNGI--LQGYRV--TYAPVTDWYGNEDAVTKQISGLHTTLSGL 350
+ ++SV +SWEP G +G+ ++ Y + P W + +V+ S + L
Sbjct: 382 VRARSVLLSWEP----GSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSF--IVDRL 435
Query: 351 RRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPS 408
+ +T+Y V A GD T + P AP + + +L+ W PP+
Sbjct: 436 KPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPA 495
Query: 409 SP--NGVLVGYTL-YMSVIEDGREEGTHKRMLSP 439
NG+L+G+ + Y ++ +G T + + +P
Sbjct: 496 EDKINGILLGFRIRYRELLYEGLRGFTLRGINNP 529
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSAS 131
P + +I + S I I W+ G PI Y+++ + + E W + + S + S
Sbjct: 796 PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 855
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
+ L+P SY R+IA N G PS P Q
Sbjct: 856 MDILKPGVSYDFRVIAVNDYGFGTPSSPSQ 885
Score = 47.2 bits (107), Expect = 3e-04
Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 8/176 (4%)
Query: 576 PPILAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHV- 630
P ++ + + + S+ +WS+ + D +LGY + YK + D + VE +S
Sbjct: 172 PTNVSALATTSSSMLGRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQ 231
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPC-DIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWL 688
L L Y++ + AF RIG G P + T VP P + TT+V +W
Sbjct: 232 LTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQ 291
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
G IL + I +R + + + R ++ +GL P + Y RITA
Sbjct: 292 PPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITA 346
Score = 45.6 bits (103), Expect = 0.001
Identities = 45/183 (24%), Positives = 67/183 (36%), Gaps = 7/183 (3%)
Query: 574 PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEA---GTSEH 629
P PP+ + + S+ L W IL Y I ++ VE ++
Sbjct: 270 PGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQY 329
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
L + Y ITA R G + + T+ +P M+ L
Sbjct: 330 TATGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLL 389
Query: 690 SWGDGGCG---ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
SW G G + Y+ I+ RE+ +W L S SV F V L P Y+ R+ A N
Sbjct: 390 SWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATN 449
Query: 747 NAG 749
+ G
Sbjct: 450 DIG 452
Score = 41.9 bits (94), Expect = 0.012
Identities = 46/195 (23%), Positives = 90/195 (46%), Gaps = 18/195 (9%)
Query: 570 VKVPPQ--PPILAVVDSYADSLHLQWSD----QGDGGSPILGYVINYKREHGDWEELQ-- 621
++ PP P +++ + SL L+W + +G +GY I Y R G + L
Sbjct: 61 LQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHV 120
Query: 622 -VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKH-SQMIT 678
+ ++ + +L T Y++ + AFN IG+G V T+ +VP P + S + T
Sbjct: 121 VQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALAT 180
Query: 679 LNTTTVTVWLD-SWGDGGCGILYFVIEYREM---SQPQWRLVSNSVQATERVFSVSGLTP 734
+++ + W + D +L + + Y+E +QP++ LV + + R ++GL
Sbjct: 181 TSSSMLGRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGN---SSRSAQLTGLGK 237
Query: 735 AAHYQLRITAHNNAG 749
Y++++ A G
Sbjct: 238 YVLYEVQVLAFTRIG 252
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 165 bits (400), Expect = 1e-39
Identities = 119/426 (27%), Positives = 190/426 (44%), Gaps = 24/426 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 632 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 691
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A + NL P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 692 QTTAQL-NLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 750
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P NG L Y V +++ + + S V V S+
Sbjct: 751 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 795
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 796 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 855
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 856 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 915
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 916 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 975
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRVVTVLP 478
I E G + P+ + T ++ +T ++F+ A T G G V
Sbjct: 976 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1035
Query: 479 SDSVPA 484
D A
Sbjct: 1036 VDEAMA 1041
Score = 73.3 bits (172), Expect = 4e-12
Identities = 77/325 (23%), Positives = 131/325 (40%), Gaps = 22/325 (6%)
Query: 73 PKNIRVIDQQSRTIQISWT--QPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P + + + + I+W + N P + Y V + K+ + W S +V +V+
Sbjct: 738 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS-----VVVANVS 792
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V Y +++ A N +G + V + E++P P +VRV +ST V
Sbjct: 793 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 852
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W+P G++ GY + + + S+S + T +G +++ L G
Sbjct: 853 HWDPVPLKSIRGHLQGYRIYYWKTQSSS----KRNRRHIEKKILTFQG---SKTHGMLPG 905
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+ + Y + V+ N + E VPS P +L+ + S+ + W+PP
Sbjct: 906 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPP- 963
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--TLSGLRRYTNYSVTVCAFTAA 366
NGIL Y + Y P+ + V +I T TL L T Y A T+A
Sbjct: 964 -SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1022
Query: 367 GDGVRAAPVYCHT-EEDVPSAPADI 390
G G + T +E + S DI
Sbjct: 1023 GSGSQITEEAVTTVDEAMASRQVDI 1047
Score = 64.9 bits (151), Expect = 2e-09
Identities = 65/254 (25%), Positives = 101/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 569 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 627
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 628 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 687
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT NL Y + A N IG LP + Y TK + P K P + +
Sbjct: 688 VSGTQTTAQLNLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 747
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 748 PDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 804
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 805 YLIKVQALNDMGFA 818
Score = 58.8 bits (136), Expect = 1e-07
Identities = 91/404 (22%), Positives = 156/404 (38%), Gaps = 42/404 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 633 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 688
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 689 SGTQTTAQLNLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 748
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 749 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 805
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 806 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 861
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 862 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 921
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 922 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 981
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
E G +L++ A + L NL TRY+ Y A G+G
Sbjct: 982 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1025
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 276 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 335
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 336 AIHHTISVRVKAAP 349
Score = 41.9 bits (94), Expect = 0.012
Identities = 23/120 (19%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 931 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 990
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E + D+ +
Sbjct: 991 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQ 1050
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 347 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 404
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 405 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 445
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 52 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 111
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 112 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 153
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 462 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 519
Query: 560 GRDEVTYTVEVK 571
G + +E+K
Sbjct: 520 GMAKNEVHLEIK 531
>AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein.
Length = 1471
Score = 163 bits (397), Expect = 2e-39
Identities = 99/352 (28%), Positives = 169/352 (48%), Gaps = 17/352 (4%)
Query: 70 PEMPKNIRVIDQQ--SRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
P P+ + V + +R++++ W G SPI + +Q +E P W + +
Sbjct: 755 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSI--SHE 812
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
T+ V L+P TSY LR+ A N +G S+ S + VTT ++VP PP V +++
Sbjct: 813 ATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSS 872
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+++ W+PP+ + NG + GY + ++EL + G G + T++ R
Sbjct: 873 VLIQWQPPRDESLNGLLQGYRIYYRELEYEA------GSGTEAKTLKN-----PIALRAE 921
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L+K+ Y V++ AYN E P++ P +Q L++ + V+W+
Sbjct: 922 LTDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWD 981
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
PPP +NG +QGY++ Y E + L L +T Y V++ AF A
Sbjct: 982 PPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNA 1041
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
AGDG ++ P T + P AP+ + + + + VSW P++ NG+L GY
Sbjct: 1042 AGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGY 1093
Score = 149 bits (361), Expect = 5e-35
Identities = 153/660 (23%), Positives = 276/660 (41%), Gaps = 55/660 (8%)
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+T +V L PA +Y R+ A N +G+ + S + ++ EE PS PP+++ +++
Sbjct: 3 MTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQS 62
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W+PP NG + GY + ++ +A PG Y R + +
Sbjct: 63 IMVQWQPPPETEHNGVLRGYILRYR---------LAGLPG--EYQQRNITSPEV--NYCL 109
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++ L Y + V AYN ++ VP+ PP +Q A++S +++ W
Sbjct: 110 VTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWN 169
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYG-NEDAVTKQISGLHTT-LSGLRRYTNYSVTVCAF 363
PPP + NGI QGY++ P + G+H ++ L+++T Y +V F
Sbjct: 170 PPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCF 229
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
T GDG + P T+ED P A + + VSW P NG++ GY + V
Sbjct: 230 TTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEV 289
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT--RVVTVLPSDS 481
GR L+ +T ++ T+ V+A T +G G T + + +P D
Sbjct: 290 Y--GRNNSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPD- 346
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLES---TLRKNVSS 534
+P ++ + ++P + G + W + G +G E TL + +
Sbjct: 347 LPGAPSNLVISNISPRSATLQFRPGYDG-KTSISRWIVEGQVGAIGDEEEWVTLYEEENE 405
Query: 535 DGTLTISMTQSADSGNYTCSVE--NIHGRDEVTYTVEV----KVPPQ--PPILAVVDSYA 586
+ + +Y ++ NI G + + V + PP P + V +
Sbjct: 406 PDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASE 465
Query: 587 DSLHLQW----SDQGDGGSPILGYVINYKR---EHGDWEELQVEAGTSEHVLPNLWCGTR 639
SL L+W Q +G +GY I Y R + ++ + E + L
Sbjct: 466 TSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWME 525
Query: 640 YQLYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WLDSWGDGGCG 697
Y+L + AFN +G G ++V T+ +VP P++ +++T + + W G
Sbjct: 526 YELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNG 585
Query: 698 -ILYFVIEYREMS---QPQWRLV-SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
IL + I +R +P+ +V N Q+ ++GL Y+L++ A G+ +
Sbjct: 586 LILGYKILFRAKDLDPEPRSHIVRGNHTQSA----LLAGLRKFVLYELQVLAFTRIGNGV 641
Score = 132 bits (318), Expect = 9e-30
Identities = 166/721 (23%), Positives = 284/721 (39%), Gaps = 64/721 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP----ESWPSTPQKVIVP 124
+P P N+ + + R+ + + Y G + I +IV+ + E W + ++ P
Sbjct: 347 LPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEP 406
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQS--EPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
+ + NL P T Y R+ N +G S PS V + T + P P V V S
Sbjct: 407 DA-QMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRV-IQTLQAPPDVAPTSVTVRTAS 464
Query: 183 STELIVTWEPPQRDLWNGN--ILGYYVGF--QELNSNSTVLIASGPGGASYTVRTVEGAG 238
T L + W P +NGN +GY + + +L S++ + S +T+
Sbjct: 465 ETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEE----- 519
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
L++ Y + +QA+N+ E VPS P + A+SS
Sbjct: 520 ----------LEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSST 569
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT---TLSGLRRYTN 355
+ ++W P + +NG++ GY++ + D + + + + G HT L+GLR++
Sbjct: 570 QILLTWTSVPEQDQNGLILGYKILFR-AKDL--DPEPRSHIVRGNHTQSALLAGLRKFVL 626
Query: 356 YSVTVCAFTAAGDGVRAAPVYC-HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + V AFT G+GV + P+ T++D P P + + + W PP PNG++
Sbjct: 627 YELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGII 686
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV 474
+GY + + T + + + P + + F +SA TR G GE
Sbjct: 687 LGYQIAYRLASSSPHTFTTVE-VGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLE-A 744
Query: 475 TVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVP-----APATTWTMN----GVGLE 525
TV+ ++ + R ++ P E + S VP +P +TM G
Sbjct: 745 TVITTEK--RERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEW 802
Query: 526 STLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEV-----KVPPQPP-I 578
T ++S + T + + S N G + + E VP +PP
Sbjct: 803 QTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGS 862
Query: 579 LAVVDSYADSLHLQWSDQGDG--GSPILGYVINYKR---EHGDWEELQVEAG--TSEHVL 631
++ S+ +QW D + GY I Y+ E G E + L
Sbjct: 863 VSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALRAEL 922
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WLD 689
+L RY++ +TA+N IG V + P + P++ Q+ L + + V W
Sbjct: 923 TDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP 982
Query: 690 SWGDGGCG-ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
+ G I + I Y E + E V + LT Y + I+A N A
Sbjct: 983 PPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAA 1042
Query: 749 G 749
G
Sbjct: 1043 G 1043
Score = 127 bits (307), Expect = 2e-28
Identities = 143/613 (23%), Positives = 243/613 (39%), Gaps = 48/613 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P P + + + +++I W P N I+ Y + Y+ A S P T V V +V
Sbjct: 656 PGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSS-PHTFTTVEVGATVRQ 714
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST--ELI 187
+ +L P ++Y R+ A+ R G EP + +TT + PP+++ V T L
Sbjct: 715 FTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLR 774
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT-VEGAGTARSRTTL 246
+ W P + + Y+ T+ + P G T + + TA +
Sbjct: 775 LQWVPGSD---GASPIRYF----------TMQVRELPRGEWQTYSSSISHEATA---CVV 818
Query: 247 SGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ +Y + ++A N ++DVP PPG++ ++ SV + W+
Sbjct: 819 DRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQ 878
Query: 306 PPPMRGRNGILQGYRVTYAPVT--DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
PP NG+LQGYR+ Y + G E K L L+ L++Y Y V + A+
Sbjct: 879 PPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALRAELTDLKKYRRYEVIMTAY 938
Query: 364 TAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSW--LPPSSPNGVLVGYTLY 420
G+ +APV E P+ AP +++ + +++ V+W PP S NG + GY +Y
Sbjct: 939 NIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIY 998
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT--------R 472
+ E K + P + + + + +SA G+G + +
Sbjct: 999 YWEADSQNETEKMKVLFLPEPVVRLKNLTS-HTKYLVSISAFNAAGDGPKSDPQQGRTHQ 1057
Query: 473 VVTVLPSDSVPARITSFSRNIV--TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK 530
PS + ITS + N+ P N L +V V P + GV T+
Sbjct: 1058 AAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRV-VYEPLAP--VQGVSKVVTVEV 1114
Query: 531 NVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV---KVPPQPPILAVVDSYAD 587
+ L + + + I E+ + + P P +V A
Sbjct: 1115 RGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSAS 1174
Query: 588 SLHLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAGTSEHVLPNLWCGTRYQL 642
L LQW++ G +P GYVI + + G W+ ++ A + L L G Y+
Sbjct: 1175 ELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEF 1234
Query: 643 YITAFNRIGTGLP 655
+ A N G G P
Sbjct: 1235 RVVAVNEAGYGEP 1247
Score = 120 bits (289), Expect = 3e-26
Identities = 169/712 (23%), Positives = 275/712 (38%), Gaps = 59/712 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
PKNI + +++I + W P N + YI++Y+ A + + P V
Sbjct: 50 PKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSP-EVNYC 108
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
V +L T Y +++ A N G S+ V T + VP+ PPQ+V+ EA +ST + W
Sbjct: 109 LVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLW 168
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG +N +L + TV T+ ++ L+
Sbjct: 169 NPPPQQFING-----------INQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLK 217
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
K AY V + + ED P G L + S++VSW+ P
Sbjct: 218 KFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPG-AVGHLSFTEILDTSLKVSWQEP--L 274
Query: 311 GRNGILQGYRVTYAPVTDWYG-NEDAVTKQI-SGLHT-TLSGLRRYTNYSVTVCAFTAAG 367
+NGI+ GY++++ + YG N +T + S H + GL T Y++ V A TA G
Sbjct: 275 EKNGIITGYQISW----EVYGRNNSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVG 330
Query: 368 DG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
G V ++ + D+P AP+++ + S + + P + + + V
Sbjct: 331 TGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAI 390
Query: 427 GREE---GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE---GEATRVVTVL--P 478
G EE ++ P E P ++F + +G ++RV+ L P
Sbjct: 391 GDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAP 450
Query: 479 SDSVPARI---TSFSRNIVTPW--KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
D P + T+ ++ W + + N V W + L+S+ V
Sbjct: 451 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSD---LQSSAVAQVV 507
Query: 534 SD---GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLH 590
SD TI + N G + V + P A + A+++
Sbjct: 508 SDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVS 567
Query: 591 -----LQWSD--QGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTR---- 639
L W+ + D ILGY I ++ + D E + H L G R
Sbjct: 568 STQILLTWTSVPEQDQNGLILGYKILFRAKDLD-PEPRSHIVRGNHTQSALLAGLRKFVL 626
Query: 640 YQLYITAFNRIGTGLP-CDIVHAYTKGTVPVKPKHSQMITLNTTTV-TVWLDSWGDGGCG 697
Y+L + AF RIG G+P ++ TK P P + T+V VW G
Sbjct: 627 YELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI- 685
Query: 698 ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
IL + I YR S + V AT R F+ + L P + Y R++A G
Sbjct: 686 ILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQG 737
Score = 119 bits (286), Expect = 7e-26
Identities = 170/709 (23%), Positives = 286/709 (40%), Gaps = 61/709 (8%)
Query: 73 PKNIRVIDQQSRTIQISWT----QPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P ++ V ++++ W Y GN + Y ++Y + + S +V+
Sbjct: 455 PTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRS-DLQSSAVAQVVSDRLER 513
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++ L+ Y L++ A N +G S+ V+ T E VPS P++V EA SST++++
Sbjct: 514 EFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILL 573
Query: 189 TW-EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
TW P++D NG ILGY + F+ + + P S+ VR G L+
Sbjct: 574 TWTSVPEQD-QNGLILGYKILFRAKDLD--------PEPRSHIVR-----GNHTQSALLA 619
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
GL+K Y + V A+ +D PP L + SVR+ W+PP
Sbjct: 620 GLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPP 679
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
NGI+ GY++ Y + V + T + L + Y + A T G
Sbjct: 680 --EEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQG 737
Query: 368 DGVRAAPVYCHTEE-DVPSAPADI---KAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
G TE+ + P+ P ++ +A V++R+ + + W+P S + +T+ +
Sbjct: 738 WGEPLEATVITTEKRERPAPPRELLVPQAEVTARS-LRLQWVPGSDGASPIRYFTMQVRE 796
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE---ATRVVTVL--- 477
+ G E T+ +S + R P +++ + A+ +G+ + T VT L
Sbjct: 797 LPRG-EWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDV 855
Query: 478 ---PSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS 534
P SV A + S +++ W+ S N + + T K + +
Sbjct: 856 PGEPPGSVSATPHTTS-SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKN 914
Query: 535 DGTLTISMTQSADSGNY--TCSVENIHGRDEVTYTVEVKVPPQPPILA-----VVDSYAD 587
L +T Y + NI G + VEV V P +A V A
Sbjct: 915 PIALRAELTDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTAS 974
Query: 588 SLHLQWS---DQGDGGSPILGYVINY--KREHGDWEELQVEAGTSEHV-LPNLWCGTRYQ 641
L + W + G+ I GY I Y + E+++V V L NL T+Y
Sbjct: 975 QLEVTWDPPPPESQNGN-IQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYL 1033
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGC--GIL 699
+ I+AFN G G D T P P + +TT+ V SWG+ GIL
Sbjct: 1034 VSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNV---SWGEPAAANGIL 1090
Query: 700 Y-FVIEYREMSQPQW--RLVSNSVQAT-ERVFSVSGLTPAAHYQLRITA 744
+ + Y ++ Q ++V+ V+ +R V LT Y R+ A
Sbjct: 1091 QGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 1139
Score = 112 bits (270), Expect = 6e-24
Identities = 110/444 (24%), Positives = 181/444 (40%), Gaps = 34/444 (7%)
Query: 53 DSKVTVDLRIGSLSHQVP-EMPKNIRVIDQQSRTIQISWTQPY--AGNSPIINYIVQYKE 109
DS + + + VP E P ++ + ++ I W P + N + Y + Y+E
Sbjct: 839 DSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRE 898
Query: 110 AP-ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV 168
E+ T K + A + +L+ Y + + A N +G+S S PV+V E
Sbjct: 899 LEYEAGSGTEAKTLKNPIALRAELTDLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAA 958
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P+ PQ+V+V ++++L VTW+PP + NGNI GY + + E +S +
Sbjct: 959 PAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQN------------ 1006
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG 288
++ L L H Y V + A+N+ + P P
Sbjct: 1007 -ETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG-APS 1064
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---LHT 345
L + ++S ++ VSW P NGILQGYRV Y P+ G VT ++ G
Sbjct: 1065 FLAFSEITSTTLNVSWGEP--AAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWL 1122
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
+ L + Y V A T A + E P +P D+ S +++ + W
Sbjct: 1123 KVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDV-LVTKSASELTLQWT 1181
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHK---RMLSPSTLSHETSRSPPRATHQFWVSAS 462
S + GY + ++G + K R + TLS + R T++F V A
Sbjct: 1182 EGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQ--GVTYEFRVVAV 1239
Query: 463 TRLGEGEATRVVTVLPSDSVPARI 486
G GE + PS +V A++
Sbjct: 1240 NEAGYGEPSN-----PSTAVSAQV 1258
Score = 84.6 bits (200), Expect = 2e-15
Identities = 122/505 (24%), Positives = 203/505 (40%), Gaps = 43/505 (8%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ--GYRVTYAPVTDWYGN--EDAVTK 338
P + P ++ S S+R+ W P P NG + GYR+ Y W + AV +
Sbjct: 451 PDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKY-----WRSDLQSSAVAQ 505
Query: 339 QISGL---HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAV 394
+S T+ L + Y + + AF A G G + V T E VPSA P ++ A
Sbjct: 506 VVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEA 565
Query: 395 SSRNKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR 452
S +IL++W +P NG+++GY + + E +H + T S +
Sbjct: 566 VSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHI-VRGNHTQSALLAGLRKF 624
Query: 453 ATHQFWVSASTRLGEG-EATRVVTVLPSDSVPA----------RITSFSRNIVTPWKEN- 500
++ V A TR+G G +T ++ D P R+TS P + N
Sbjct: 625 VLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNG 684
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L A ++ T V + +T+R+ ++D + + E +
Sbjct: 685 IILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEA 744
Query: 561 RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWE- 618
T E PP+ ++ + A SL LQW DG SPI + + + G+W+
Sbjct: 745 TVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQT 804
Query: 619 -ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQM 676
+ + V+ L T Y+L + A N IG + + T VP +P S
Sbjct: 805 YSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVS 864
Query: 677 ITLNTTTVTV--W---LDSWGDG---GCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
T +TT+ + W D +G G I Y +EY S + + + N +
Sbjct: 865 ATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALRA---E 921
Query: 729 VSGLTPAAHYQLRITAHNNAGHALA 753
++ L Y++ +TA+N G + A
Sbjct: 922 LTDLKKYRRYEVIMTAYNIIGESPA 946
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
P P+++ V S + + WT+ ++G++P Y+++ + + E W + + P S T
Sbjct: 1161 PGSPRDVLVTKSASE-LTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDI--PRSAT 1217
Query: 129 S--ASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEVP 169
S S+ L+ +Y R++A N G EPS P V+ E P
Sbjct: 1218 SYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 1261
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus protein.
Length = 1236
Score = 163 bits (396), Expect = 3e-39
Identities = 122/447 (27%), Positives = 200/447 (44%), Gaps = 27/447 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 644 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 703
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 704 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 762
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P NG L Y V +++ + + S V V S+
Sbjct: 763 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 807
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 808 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 867
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 868 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 927
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 928 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 987
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGE---ATRVVT 475
I E G + P+ + T ++ +T ++F+ A T G G V T
Sbjct: 988 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1047
Query: 476 VLPSDSVPARITSFSRNIVTPWKENIS 502
V + +P + + V P N++
Sbjct: 1048 VDEAGILPPDVGAGKVQAVNPRISNLT 1074
Score = 68.5 bits (160), Expect = 1e-10
Identities = 113/512 (22%), Positives = 197/512 (38%), Gaps = 56/512 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 645 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 700
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 701 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 817
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 818 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 873
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 874 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 933
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 934 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 993
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGT 666
E G +L++ A + L NL TRY+ Y A G+G + G
Sbjct: 994 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1053
Query: 667 VP-------VKPKHSQMITLNTTTVTVWLD-SWGDGGCGILYFVIEYREM-SQPQWRLVS 717
+P V+ + ++ L + + SW G + F +EY S+ +WR
Sbjct: 1054 LPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWR--K 1111
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + F + GL P Y++R+ A ++G
Sbjct: 1112 EIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
Score = 62.5 bits (145), Expect = 8e-09
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 581 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 639
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 640 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 699
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 700 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 759
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 760 PDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 816
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 817 YLIKVQALNDMGFA 830
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/202 (21%), Positives = 79/202 (39%), Gaps = 7/202 (3%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 943 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 1002
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E PP +
Sbjct: 1003 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGK 1062
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
++ I + + NI Y G + +N + G G+ R E
Sbjct: 1063 VQAVNPRISNLTAAAAETY-ANISWEYEGPEHVN----FYVEYGVAGSKEEWRK-EIVNG 1116
Query: 240 ARSRTTLSGLQKHAAYAVVVQA 261
+RS L GL AY V V A
Sbjct: 1117 SRSFFGLKGLMPGTAYKVRVGA 1138
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 288 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 347
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 348 AIHHTISVRVKAAP 361
Score = 37.9 bits (84), Expect = 0.20
Identities = 63/267 (23%), Positives = 100/267 (37%), Gaps = 26/267 (9%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 474 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531
Query: 560 GRDEVTYTVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD 616
G + +E+K P + P AVV + + + D + + RE
Sbjct: 532 GMAKNEVHLEIKDPTWIVKQPEYAVVQR-GSMVSFECKVKHDHTLSLTVLWLKDNRELPS 590
Query: 617 WEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV--- 669
E V+ +H+ + + GT + T + + +V A T PV
Sbjct: 591 DERFTVD---KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV-APTPTPAPVYDV 646
Query: 670 -KPKHSQMIT--LNTTTVTVWLDSWGDGGCGILYFVIEYRE-MSQPQWRLVSNSVQATER 725
P +T L+ + W D I F+IEY + M +P V T+
Sbjct: 647 PNPPFDLELTDQLDKSVQLSWTPG-DDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 705
Query: 726 VFSVSGLTPAAHYQLRITAHNNAGHAL 752
+ L+P +Y R+ A N+ G +L
Sbjct: 706 TAQLK-LSPYVNYSFRVMAVNSIGKSL 731
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 359 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 416
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 417 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 457
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 146
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 163 bits (396), Expect = 3e-39
Identities = 122/447 (27%), Positives = 200/447 (44%), Gaps = 27/447 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 644 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 703
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 704 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 762
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P NG L Y V +++ + + S V V S+
Sbjct: 763 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 807
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 808 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 867
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 868 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 927
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 928 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 987
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGE---ATRVVT 475
I E G + P+ + T ++ +T ++F+ A T G G V T
Sbjct: 988 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1047
Query: 476 VLPSDSVPARITSFSRNIVTPWKENIS 502
V + +P + + V P N++
Sbjct: 1048 VDEAGILPPDVGAGKVQAVNPRISNLT 1074
Score = 68.5 bits (160), Expect = 1e-10
Identities = 113/512 (22%), Positives = 197/512 (38%), Gaps = 56/512 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 645 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 700
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 701 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 817
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 818 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 873
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 874 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 933
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 934 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 993
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGT 666
E G +L++ A + L NL TRY+ Y A G+G + G
Sbjct: 994 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1053
Query: 667 VP-------VKPKHSQMITLNTTTVTVWLD-SWGDGGCGILYFVIEYREM-SQPQWRLVS 717
+P V+ + ++ L + + SW G + F +EY S+ +WR
Sbjct: 1054 LPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWR--K 1111
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + F + GL P Y++R+ A ++G
Sbjct: 1112 EIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1143
Score = 62.5 bits (145), Expect = 8e-09
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 581 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 639
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 640 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 699
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 700 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 759
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 760 PDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 816
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 817 YLIKVQALNDMGFA 830
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/202 (21%), Positives = 79/202 (39%), Gaps = 7/202 (3%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 943 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 1002
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E PP +
Sbjct: 1003 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGK 1062
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
++ I + + NI Y G + +N + G G+ R E
Sbjct: 1063 VQAVNPRISNLTAAAAETY-ANISWEYEGPEHVN----FYVEYGVAGSKEEWRK-EIVNG 1116
Query: 240 ARSRTTLSGLQKHAAYAVVVQA 261
+RS L GL AY V V A
Sbjct: 1117 SRSFFGLKGLMPGTAYKVRVGA 1138
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 288 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 347
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 348 AIHHTISVRVKAAP 361
Score = 37.9 bits (84), Expect = 0.20
Identities = 63/267 (23%), Positives = 100/267 (37%), Gaps = 26/267 (9%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 474 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531
Query: 560 GRDEVTYTVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD 616
G + +E+K P + P AVV + + + D + + RE
Sbjct: 532 GMAKNEVHLEIKDPTWIVKQPEYAVVQR-GSMVSFECKVKHDHTLSLTVLWLKDNRELPS 590
Query: 617 WEELQVEAGTSEHV----LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV--- 669
E V+ +H+ + + GT + T + + +V A T PV
Sbjct: 591 DERFTVD---KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV-APTPTPAPVYDV 646
Query: 670 -KPKHSQMIT--LNTTTVTVWLDSWGDGGCGILYFVIEYRE-MSQPQWRLVSNSVQATER 725
P +T L+ + W D I F+IEY + M +P V T+
Sbjct: 647 PNPPFDLELTDQLDKSVQLSWTPG-DDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 705
Query: 726 VFSVSGLTPAAHYQLRITAHNNAGHAL 752
+ L+P +Y R+ A N+ G +L
Sbjct: 706 TAQLK-LSPYVNYSFRVMAVNSIGKSL 731
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 359 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 416
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 417 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 457
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 146
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 163 bits (395), Expect = 4e-39
Identities = 118/426 (27%), Positives = 190/426 (44%), Gaps = 24/426 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 625 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 684
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 685 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 743
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P NG L Y V +++ + + S V V S+
Sbjct: 744 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 788
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 789 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 848
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 849 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 908
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 909 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 968
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRVVTVLP 478
I E G + P+ + T ++ +T ++F+ A T G G V
Sbjct: 969 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTT 1028
Query: 479 SDSVPA 484
D A
Sbjct: 1029 VDEAMA 1034
Score = 73.3 bits (172), Expect = 4e-12
Identities = 77/325 (23%), Positives = 131/325 (40%), Gaps = 22/325 (6%)
Query: 73 PKNIRVIDQQSRTIQISWT--QPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P + + + + I+W + N P + Y V + K+ + W S +V +V+
Sbjct: 731 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS-----VVVANVS 785
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V Y +++ A N +G + V + E++P P +VRV +ST V
Sbjct: 786 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 845
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W+P G++ GY + + + S+S + T +G +++ L G
Sbjct: 846 HWDPVPLKSIRGHLQGYRIYYWKTQSSS----KRNRRHIEKKILTFQG---SKTHGMLPG 898
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+ + Y + V+ N + E VPS P +L+ + S+ + W+PP
Sbjct: 899 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPP- 956
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--TLSGLRRYTNYSVTVCAFTAA 366
NGIL Y + Y P+ + V +I T TL L T Y A T+A
Sbjct: 957 -SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1015
Query: 367 GDGVRAAPVYCHT-EEDVPSAPADI 390
G G + T +E + S DI
Sbjct: 1016 GSGSQITEEAVTTVDEAMASRQVDI 1040
Score = 62.5 bits (145), Expect = 8e-09
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 562 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 620
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 621 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 680
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 681 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 740
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 741 PDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 797
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 798 YLIKVQALNDMGFA 811
Score = 58.0 bits (134), Expect = 2e-07
Identities = 91/404 (22%), Positives = 156/404 (38%), Gaps = 42/404 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 626 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 681
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 682 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 741
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 742 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 798
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 799 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 854
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 855 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 914
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 915 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 974
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
E G +L++ A + L NL TRY+ Y A G+G
Sbjct: 975 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1018
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 269 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 328
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 329 AIHHTISVRVKAAP 342
Score = 41.9 bits (94), Expect = 0.012
Identities = 23/120 (19%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 924 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 983
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E + D+ +
Sbjct: 984 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQ 1043
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 340 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 397
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 398 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 438
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 146
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 455 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512
Query: 560 GRDEVTYTVEVK 571
G + +E+K
Sbjct: 513 GMAKNEVHLEIK 524
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 162 bits (394), Expect = 5e-39
Identities = 115/410 (28%), Positives = 187/410 (45%), Gaps = 24/410 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 625 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 684
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 685 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 743
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P NG L Y V +++ + + S V V S+
Sbjct: 744 LVITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 788
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 789 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 848
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 849 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 908
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 909 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 968
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEG 468
I E G + P+ + T ++ +T ++F+ A T G G
Sbjct: 969 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1018
Score = 77.4 bits (182), Expect = 3e-13
Identities = 79/333 (23%), Positives = 136/333 (40%), Gaps = 23/333 (6%)
Query: 73 PKNIRVIDQQSRTIQISWT--QPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P + + + + I+W + N P + Y V + K+ + W S +V +V+
Sbjct: 731 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS-----VVVANVS 785
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V Y +++ A N +G + V + E++P P +VRV +ST V
Sbjct: 786 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 845
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W+P G++ GY + + + S+S + T +G +++ L G
Sbjct: 846 HWDPVPLKSIRGHLQGYRIYYWKTQSSS----KRNRRHIEKKILTFQG---SKTHGMLPG 898
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+ + Y + V+ N + E VPS P +L+ + S+ + W+PP
Sbjct: 899 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPP- 956
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--TLSGLRRYTNYSVTVCAFTAA 366
NGIL Y + Y P+ + V +I T TL L T Y A T+A
Sbjct: 957 -SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1015
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKA--AVSSR 397
G G + T ++ P D+ A A++SR
Sbjct: 1016 GSGSQITEEAVTTVDEAGILPPDVGAGKAMASR 1048
Score = 62.5 bits (145), Expect = 8e-09
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 562 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 620
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 621 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 680
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 681 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 740
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 741 PDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 797
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 798 YLIKVQALNDMGFA 811
Score = 58.0 bits (134), Expect = 2e-07
Identities = 91/404 (22%), Positives = 156/404 (38%), Gaps = 42/404 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 626 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 681
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 682 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 741
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 742 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 798
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 799 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 854
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 855 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 914
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 915 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 974
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
E G +L++ A + L NL TRY+ Y A G+G
Sbjct: 975 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1018
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 269 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 328
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 329 AIHHTISVRVKAAP 342
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/127 (20%), Positives = 55/127 (43%), Gaps = 1/127 (0%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 924 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 983
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E PP +
Sbjct: 984 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGK 1043
Query: 180 AKSSTEL 186
A +S ++
Sbjct: 1044 AMASRQV 1050
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 340 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 397
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 398 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 438
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 146
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 455 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512
Query: 560 GRDEVTYTVEVK 571
G + +E+K
Sbjct: 513 GMAKNEVHLEIK 524
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 160 bits (389), Expect = 2e-38
Identities = 118/424 (27%), Positives = 188/424 (44%), Gaps = 24/424 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+ T
Sbjct: 630 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 689
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTELI 187
+A ++ L P +Y R++A N +G+S PS+ Q T P P V L+
Sbjct: 690 TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 748
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+TW+P NG L Y V +++ + + S V V S+ +S
Sbjct: 749 ITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYIVS 793
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
G Y + VQA N ED+P + PG ++ N ++S V W+P
Sbjct: 794 GTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV 853
Query: 308 PMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVTVC 361
P++ G LQGYR+ Y + N + K+I S H L GL ++Y++ V
Sbjct: 854 PLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPLSHYTLNVR 913
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 914 VVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKY 973
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRVVTVLPSD 480
I E G + P+ + T ++ +T ++F+ A T G G V D
Sbjct: 974 QPINSTHELGPLVDLKIPTNKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVD 1033
Query: 481 SVPA 484
A
Sbjct: 1034 EAMA 1037
Score = 71.7 bits (168), Expect = 1e-11
Identities = 77/325 (23%), Positives = 131/325 (40%), Gaps = 22/325 (6%)
Query: 73 PKNIRVIDQQSRTIQISWT--QPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P + + + + I+W + N P + Y V + K+ + W S +V +V+
Sbjct: 734 PTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS-----VVVANVS 788
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V Y +++ A N +G + V + E++P P +VRV +ST V
Sbjct: 789 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 848
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W+P G++ GY + + + S+S + T +G +++ L G
Sbjct: 849 HWDPVPLKSIRGHLQGYRIYYWKTQSSS----KRNRRHIEKKILTFQG---SKTHGMLPG 901
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+ + Y + V+ N + E VPS P +L+ + S+ + W+PP
Sbjct: 902 LEPLSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPP- 959
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--TLSGLRRYTNYSVTVCAFTAA 366
NGIL Y + Y P+ + V +I T TL L T Y A T+A
Sbjct: 960 -SHPNGILTEYTLKYQPINSTHELGPLVDLKIPTNKTRWTLKNLNFSTRYKFYFYAQTSA 1018
Query: 367 GDGVRAAPVYCHT-EEDVPSAPADI 390
G G + T +E + S DI
Sbjct: 1019 GSGSQITEEAVTTVDEAMASRQVDI 1043
Score = 68.9 bits (161), Expect = 9e-11
Identities = 64/244 (26%), Positives = 95/244 (38%), Gaps = 13/244 (5%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP 576
W + L S R V D L ++ DSG YTC + + V P P
Sbjct: 575 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNP 633
Query: 577 PI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQVEAGTSEHVLP 632
P L + D S+ L W+ D SPI ++I Y+ + G W +GT
Sbjct: 634 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL 693
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLNTTTVTV-W-- 687
L Y + A N IG LP + Y TK + P K P + + + + W
Sbjct: 694 KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKP 753
Query: 688 LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNN 747
L+ + G G+ Y V ++ +W V V A + VSG Y +++ A N+
Sbjct: 754 LNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVPYLIKVQALND 810
Query: 748 AGHA 751
G A
Sbjct: 811 MGFA 814
Score = 56.4 bits (130), Expect = 5e-07
Identities = 90/404 (22%), Positives = 155/404 (38%), Gaps = 42/404 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 629 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 684
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 685 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 744
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ ++++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 745 DNLVITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 801
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 802 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 857
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 858 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPLSHYTLNVRVVNG 917
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 918 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 977
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
E G +L++ + L NL TRY+ Y A G+G
Sbjct: 978 STHELGPLVDLKIPTNKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 282 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 341
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 342 AIHHTISVRVKAAP 355
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/120 (19%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 927 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 986
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E + D+ +
Sbjct: 987 DLKIPTNKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQ 1046
Score = 39.1 bits (87), Expect = 0.086
Identities = 58/257 (22%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 468 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
Query: 560 GRDEVTYTVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD 616
G + +E+K P + P AVV + + + D + + RE
Sbjct: 526 GMAKNEVHLEIKDPTWIVKQPEYAVVQR-GSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E V+ +H++ Y N + V + VP P ++
Sbjct: 585 DERFTVD---KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV--DVPNPPFDLEL 639
Query: 677 ITLNTTTVTVWLDSWGDGGCGILYFVIEYRE-MSQPQWRLVSNSVQATERVFSVSGLTPA 735
+V + D I F+IEY + M +P V T+ + L+P
Sbjct: 640 TDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLK-LSPY 698
Query: 736 AHYQLRITAHNNAGHAL 752
+Y R+ A N+ G +L
Sbjct: 699 VNYSFRVMAVNSIGKSL 715
Score = 37.1 bits (82), Expect = 0.35
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 11/111 (9%)
Query: 477 LPSDSV-PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKN 531
+P D V P IT S ++ + +ENI + C G P P+ +WT NG + L
Sbjct: 32 VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
Query: 532 VSSDGTLTISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
GTL I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 92 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 140
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 353 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 410
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 411 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 451
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 160 bits (388), Expect = 3e-38
Identities = 115/410 (28%), Positives = 186/410 (45%), Gaps = 24/410 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+
Sbjct: 639 YDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGT 698
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 699 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 757
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L +TW+P NG L Y V +++ + + S V V S+
Sbjct: 758 LEITWKPLNGFESNGPGLQYKVSWRQKDGDDE--------WTSVVVANV-------SKYI 802
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 803 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 862
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 863 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 922
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPSAP+ +K + + + + W PPS PNG+L YTL
Sbjct: 923 VRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 982
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEG 468
I E G + P+ + T ++ +T ++F+ A T G G
Sbjct: 983 KYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1032
Score = 78.2 bits (184), Expect = 2e-13
Identities = 76/326 (23%), Positives = 132/326 (40%), Gaps = 21/326 (6%)
Query: 73 PKNIRVIDQQSRTIQISWT--QPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P + + + ++I+W + N P + Y V + K+ + W S +V +V+
Sbjct: 745 PTAVEGLGSEPDNLEITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS-----VVVANVS 799
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V Y +++ A N +G + V + E++P P +VRV +ST V
Sbjct: 800 KYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV 859
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W+P G++ GY + + + S+S + T +G +++ L G
Sbjct: 860 HWDPVPLKSIRGHLQGYRIYYWKTQSSS----KRNRRHIEKKILTFQG---SKTHGMLPG 912
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+ + Y + V+ N + E VPS P +L+ + S+ + W+PP
Sbjct: 913 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPP- 970
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--TLSGLRRYTNYSVTVCAFTAA 366
NGIL Y + Y P+ + V +I T TL L T Y A T+A
Sbjct: 971 -SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1029
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKA 392
G G + T ++ P D+ A
Sbjct: 1030 GSGSQITEEAVTTVDEAGILPPDVGA 1055
Score = 67.7 bits (158), Expect = 2e-10
Identities = 113/512 (22%), Positives = 197/512 (38%), Gaps = 56/512 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP+ PP L+ +SV++SW P N + + + Y G T ++
Sbjct: 640 DVPN-PPFDLELTDQLDKSVQLSWTPGD--DNNSPITKFIIEYEDAMHKPGLWHHQT-EV 695
Query: 341 SGLHTTLS-GLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEEDVPSAPADIKAAVSSR 397
SG TT L Y NYS V A + G + A+ Y + P ++ S
Sbjct: 696 SGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 755
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+ + ++W P + NG + Y + +DG +E T + + S + S +P +
Sbjct: 756 DNLEITWKPLNGFESNGPGLQYKVSWRQ-KDGDDEWTSVVVANVS--KYIVSGTPTFVPY 812
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPA 514
V A +G VV + +P R N+V + VP +
Sbjct: 813 LIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD----PVPLKS 868
Query: 515 TTWTMNGVGL-----ESTLRKN--------VSSDGTLTISMTQSADS-GNYTCSVENIHG 560
+ G + +S+ ++N ++ G+ T M + +YT +V ++G
Sbjct: 869 IRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNG 928
Query: 561 RDEV------TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK--- 611
+ E + VP P L +V+ DSL L+W + Y + Y+
Sbjct: 929 KGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPIN 988
Query: 612 --REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGT 666
E G +L++ A + L NL TRY+ Y A G+G + G
Sbjct: 989 STHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGI 1048
Query: 667 VP-------VKPKHSQMITLNTTTVTVWLD-SWGDGGCGILYFVIEYREM-SQPQWRLVS 717
+P V+ ++++ L + + SW G + F +EY S+ +WR
Sbjct: 1049 LPPDVGAGKVQAVNTRISNLTAAAAETYANISWEYEGPEHVNFYVEYGVAGSKEEWR--K 1106
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + F + GL P Y++R+ A ++G
Sbjct: 1107 EIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSG 1138
Score = 62.1 bits (144), Expect = 1e-08
Identities = 64/254 (25%), Positives = 100/254 (39%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 576 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 634
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP L + D S+ L W+ D SPI ++I Y+ + G W
Sbjct: 635 PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 694
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 695 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 754
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V ++ +W V V A + VSG
Sbjct: 755 PDNLEITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV---VVANVSKYIVSGTPTFVP 811
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 812 YLIKVQALNDMGFA 825
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/202 (21%), Positives = 79/202 (39%), Gaps = 7/202 (3%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 938 RVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLV 997
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +P + T +++NL +T Y A+ G VTT +E PP +
Sbjct: 998 DLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGK 1057
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
++ I + + NI Y G + +N + G G+ R E
Sbjct: 1058 VQAVNTRISNLTAAAAETY-ANISWEYEGPEHVN----FYVEYGVAGSKEEWRK-EIVNG 1111
Query: 240 ARSRTTLSGLQKHAAYAVVVQA 261
+RS L GL AY V V A
Sbjct: 1112 SRSFFGLKGLMPGTAYKVRVGA 1133
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 283 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 342
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 343 AIHHTISVRVKAAP 356
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 354 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 411
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 412 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 452
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 40 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 99
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 100 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 141
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 155 bits (377), Expect = 6e-37
Identities = 120/447 (26%), Positives = 196/447 (43%), Gaps = 27/447 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+ VP P ++ + DQ +++Q+SWT NSPI +Y++A + V G+
Sbjct: 639 YDVPNPPLDLELTDQLDKSVQLSWTPGDDNNSPITTIHDEYEDAMHKPGLWHHQTEVSGT 698
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T+A ++ L P +Y R++A N +G+S PS+ Q T P P V
Sbjct: 699 QTTAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDN 757
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++TW+P +NG L Y V +++ G +T V S+
Sbjct: 758 LVITWKPLNGFEFNGPGLQYKVSWRQK-----------VGDDEWTSVVVANV----SKYI 802
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+SG Y + VQA N ED+P + PG ++ N ++S V W+
Sbjct: 803 VSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWD 862
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQI-----SGLHTTLSGLRRYTNYSVT 359
P P++ G LQGYR+ Y + N + K+I S H L GL +++Y++
Sbjct: 863 PVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLN 922
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V G+G + +T E VPS P+ +K + + + + W PPS PNG+L YTL
Sbjct: 923 VRVVNGKGEGPASPDRVFNTPEGVPSVPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTL 982
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGE---ATRVVT 475
I + E G + P+ + T ++ T ++F+ A T G G V T
Sbjct: 983 KYQPINNTHELGPLVDLKIPANKTRWTLKNLNFTTRYKFYFYAQTSAGSGSQITEEAVTT 1042
Query: 476 VLPSDSVPARITSFSRNIVTPWKENIS 502
V + +P + + V P N++
Sbjct: 1043 VDEAGILPPDVGAGKVQAVNPRISNLT 1069
Score = 56.8 bits (131), Expect = 4e-07
Identities = 63/254 (24%), Positives = 99/254 (38%), Gaps = 23/254 (9%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC----SVENIHGRDEVTYTVEVKV 572
W + L S R V D L ++ DSG YTC +++++ ++
Sbjct: 576 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 634
Query: 573 P------PQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQV 622
P P PP+ L + D S+ L W+ D SPI Y+ + G W
Sbjct: 635 PAPVYDVPNPPLDLELTDQLDKSVQLSWTPGDDNNSPITTIHDEYEDAMHKPGLWHHQTE 694
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK-PKHSQMITLN 680
+GT L Y + A N IG LP + Y TK + P K P + +
Sbjct: 695 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 754
Query: 681 TTTVTV-W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ + W L+ + G G+ Y V +++ +W V V A + VSG
Sbjct: 755 PDNLVITWKPLNGFEFNGPGLQYKVSWRQKVGDDEWTSV---VVANVSKYIVSGTPTFVP 811
Query: 738 YQLRITAHNNAGHA 751
Y +++ A N+ G A
Sbjct: 812 YLIKVQALNDMGFA 825
Score = 51.6 bits (118), Expect = 2e-05
Identities = 56/240 (23%), Positives = 94/240 (39%), Gaps = 26/240 (10%)
Query: 529 RKNVSSDGTLTISMTQSADS-GNYTCSVENIHGRDEV------TYTVEVKVPPQPPILAV 581
+K ++ G+ T M + +YT +V ++G+ E + VP P L +
Sbjct: 896 KKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSVPSSLKI 955
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYK-----REHGDWEELQVEAGTSEHVLPNLWC 636
V+ DSL L+W + Y + Y+ E G +L++ A + L NL
Sbjct: 956 VNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINNTHELGPLVDLKIPANKTRWTLKNLNF 1015
Query: 637 GTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVP-------VKPKHSQMITLNTTTVTV 686
TRY+ Y A G+G + G +P V+ + ++ L
Sbjct: 1016 TTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAET 1075
Query: 687 WLD-SWGDGGCGILYFVIEYREM-SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ + SW G F +EY S+ +WR V + F + GL P Y+ R+ A
Sbjct: 1076 YANISWEYEGPEYANFYVEYGVAGSKEEWR--KEIVNGSRSFFGLKGLMPGTAYKFRVGA 1133
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 283 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 342
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 343 AIHHTISVRVKAAP 356
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/114 (21%), Positives = 49/114 (42%), Gaps = 1/114 (0%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP-Q 119
R+ + VP +P ++++++ ++ + W P N + Y ++Y+ + P
Sbjct: 938 RVFNTPEGVPSVPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINNTHELGPLV 997
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
+ +P + T +++NL T Y A+ G VTT +E PP
Sbjct: 998 DLKIPANKTRWTLKNLNFTTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPP 1051
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 354 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 411
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 412 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 452
Score = 36.7 bits (81), Expect = 0.46
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 469 LDCAFFGSPLPTIQWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 526
Query: 560 GRDEVTYTVEVKVP 573
G + +E+K P
Sbjct: 527 GMAKNEVHLEIKDP 540
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 483 PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTL 538
P IT S ++ + +ENI + C G P P+ +WT NG + L GTL
Sbjct: 40 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 99
Query: 539 TISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 100 IINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 141
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 155 bits (376), Expect = 8e-37
Identities = 116/436 (26%), Positives = 201/436 (46%), Gaps = 31/436 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPS-TPQKVIVPGSV 127
P P+N++V + T Q+SW + +SP+I+Y +Q + W + T ++ G
Sbjct: 490 PGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKT 549
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE-VPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R++A N++G EPS P + TEE VP PP +V S +EL
Sbjct: 550 HTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSEL 609
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTV-LIASGPGGASYTVRTVEGAGTARSRTT 245
++TW+P +L NG GY V F+ L + + + + P Y R
Sbjct: 610 VITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRN------------ 657
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ ++ Y V V YN++ E+ P++ P + N+LSS + VSW
Sbjct: 658 -ESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWN 716
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK-QISGLHTT--LSGLRRYTNYSVTVCA 362
P + NG L GY V Y + G E++ +K +++G T+ L GL+ Y V A
Sbjct: 717 TIPWKLSNGHLLGYEVRY---WNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRA 773
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPNGVLVGYTLY 420
+ +AG G +A V T++ PS P ++ K+L++W + + GY ++
Sbjct: 774 YNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVF 833
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+ ++L+ + S E P + + V A+T G+G ++ + +
Sbjct: 834 YRT-----SSQNNVQVLNTNKTSAELV-LPIKEDYIIEVKATTDGGDGTSSEQIRIPRIT 887
Query: 481 SVPARITSFSRNIVTP 496
S+ AR ++ + + V P
Sbjct: 888 SMDARGSTSAISNVHP 903
Score = 60.1 bits (139), Expect = 4e-08
Identities = 76/292 (26%), Positives = 115/292 (39%), Gaps = 30/292 (10%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPAT--TWTMNGVGLE-----STLRK-NVSS 534
P RIT N+ E++ L C P TW NG + S K SS
Sbjct: 391 PTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSS 450
Query: 535 DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE--VKVPPQPPILAVVDSYAD-SLHL 591
G L I Q SG Y C V+ G D V+ + V+ P PP VD D + L
Sbjct: 451 SGDLMIRNIQLKHSGKYVCMVQT--GVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQL 508
Query: 592 QWSDQGDGGSPILGYVINYKREHG-DWEELQ-----VEAGTSEHVLPNLWCGTRYQLYIT 645
W + D SP++ Y I + W+ + ++ T + L Y+ +
Sbjct: 509 SWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVV 568
Query: 646 AFNRIGTG---LPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTVWLDSWGD---GGCGI 698
A N+IG G LP + V T+ VP V P + + + + D + G G
Sbjct: 569 ASNKIGGGEPSLPSEKVR--TEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGF 626
Query: 699 LYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
Y V+ +R + W + V S VF + P + Y++++ +NN G
Sbjct: 627 GY-VVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKG 677
Score = 50.4 bits (115), Expect = 3e-05
Identities = 55/260 (21%), Positives = 104/260 (40%), Gaps = 15/260 (5%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C P ++W V ++ R ++ +DG L I+ AD+G YTC EN G
Sbjct: 319 VSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFG 378
Query: 561 RDEVTYTVEVKVPPQPPIL-AVVD-SYADSLHLQWSDQGDGGSPIL------GYVINYKR 612
+ T + V P + + + +D S +S+ L Q D I+ G + ++K+
Sbjct: 379 KANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKK 438
Query: 613 EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPK 672
+ +E++ G+S L ++ + G +G+ P P+
Sbjct: 439 DGSHFEKV---GGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS-PGPPE 494
Query: 673 HSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVS---NSVQATERVFSV 729
+ ++ + TT + D ++ + I+ R W+ V+ + +V
Sbjct: 495 NVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATV 554
Query: 730 SGLTPAAHYQLRITAHNNAG 749
L P Y+ R+ A N G
Sbjct: 555 VELNPWVEYEFRVVASNKIG 574
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
++++ C G P P+ W NG L R + + G LTIS DSG + C EN
Sbjct: 224 EDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIEN-GALTISNLSVTDSGMFQCIAEN 282
Query: 558 IHGRDEVTYTVEVKVPPQPP 577
HG V + E+KV P
Sbjct: 283 KHGL--VYSSAELKVVASAP 300
Score = 37.1 bits (82), Expect = 0.35
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+ L C +G P P W + G+ S ++ S G L I Q D+G+Y C EN
Sbjct: 137 VKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFS-GVLEIPNFQQEDAGSYECIAENSR 195
Query: 560 GRD 562
G++
Sbjct: 196 GKN 198
>X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1
protein.
Length = 824
Score = 151 bits (367), Expect = 1e-35
Identities = 117/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 279 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 334
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 335 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 393
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 394 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 437
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 438 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 497
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 498 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 556
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +LV W PP S NGVL GY L +++G +
Sbjct: 557 FTFSTPEGVPGHPEALHLECQSNTSLLVRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 616
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 617 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 652
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 167 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 226
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 227 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 286
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 287 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 346
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 347 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 406
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 407 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 443
Score = 47.6 bits (108), Expect = 2e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 275 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 333
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 334 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 393
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 394 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 450
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 451 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 510
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 511 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 569
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 570 EALHLECQSNTSLLVRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 628
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 629 TDLSPHLRYRFQLQATTKEGPGEAI 653
Score = 36.3 bits (80), Expect = 0.61
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
C G P P TW +NG+ +E + K G L +S Q +D+ C N HG
Sbjct: 2 CQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 59
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 72 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 131
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 132 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 162
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion molecule
L1 protein.
Length = 1257
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 686
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 687 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 746 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 789
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 908
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 909 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 968
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 519 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 579 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 638
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 639 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 698
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 759 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 627 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 685
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 746 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 921
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 922 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 980
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 981 TDLSPHLRYRFQLQATTKEGPGEAI 1005
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 348 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 407
Query: 557 NIHG 560
N HG
Sbjct: 408 NRHG 411
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 246 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 305
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 306 DDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 424 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 483
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 484 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 514
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion molecule
L1 protein.
Length = 1257
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 686
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 687 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 746 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 789
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 908
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 909 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 968
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 519 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 579 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLVTQSQVRVSWSPA 638
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 639 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 698
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 759 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 627 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 685
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 746 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 921
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 922 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 980
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 981 TDLSPHLRYRFQLQATTKEGPGEAI 1005
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 348 ETARLDCQVEGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 407
Query: 557 NIHG 560
N HG
Sbjct: 408 NRHG 411
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 424 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 483
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 484 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 514
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 686
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 687 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 746 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 789
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 908
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 909 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 968
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 519 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 579 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 638
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 639 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 698
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 759 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 627 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 685
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 746 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 921
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 922 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 980
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 981 TDLSPHLRYRFQLQATTKEGPGEAI 1005
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 348 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 407
Query: 557 NIHG 560
N HG
Sbjct: 408 NRHG 411
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 246 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 305
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 306 DDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 424 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 483
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 484 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 514
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 686
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 687 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 746 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 789
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 908
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 909 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 968
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 519 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 579 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 638
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 639 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 698
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 759 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 627 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 685
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 746 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 921
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 922 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 980
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 981 TDLSPHLRYRFQLQATTKEGPGEAI 1005
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 348 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 407
Query: 557 NIHG 560
N HG
Sbjct: 408 NRHG 411
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 246 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 305
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 306 DDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 424 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 483
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 484 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 514
>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 631 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 686
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 687 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 746 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 789
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 908
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 909 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 968
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 519 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 579 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 638
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 639 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 698
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 759 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 627 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 685
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 746 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 921
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 922 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 980
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 981 TDLSPHLRYRFQLQATTKEGPGEAI 1005
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 348 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 407
Query: 557 NIHG 560
N HG
Sbjct: 408 NRHG 411
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 246 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 305
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 306 DDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 424 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 483
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 484 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 514
>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1255
Score = 150 bits (364), Expect = 2e-35
Identities = 116/396 (29%), Positives = 177/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ APE W S + VPG+ TS +++ L P Y
Sbjct: 629 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK---VPGNQTSTTLK-LSPYVHYT 684
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 685 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 743
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 744 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 787
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 788 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 847
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 848 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 906
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 907 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 966
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 967 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1002
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/281 (22%), Positives = 104/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 517 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 576
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 577 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 636
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + W L G L Y +TA N+ G G
Sbjct: 637 EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 696
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 697 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 756
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 757 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 793
Score = 47.2 bits (107), Expect = 3e-04
Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E E+ + P + T + P +
Sbjct: 625 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKV-PGNQTSTTLKLSPYVHY 683
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 684 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 743
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 744 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 800
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 801 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 860
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 861 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 919
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 920 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 978
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 979 TDLSPHLRYRFQLQATTKEGPGEAI 1003
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 346 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 405
Query: 557 NIHG 560
N HG
Sbjct: 406 NRHG 409
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 244 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE 303
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 304 DDGEYRCLAENSLGSARHAYYVTVEAAP 331
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 422 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 481
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 482 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 512
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 148 bits (359), Expect = 9e-35
Identities = 104/363 (28%), Positives = 162/363 (44%), Gaps = 21/363 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 565
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 566 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 625
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 673
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 674 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 733
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI---SGLHTTLSGLRRYTNYSVTVCAFTA 365
++G ++GY+VTY + + + + + TT+SGL T YSVTV A+T
Sbjct: 734 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTT 793
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
GDG R+ P T VP P + + ++ N L+ W PP G L+GY L +
Sbjct: 794 KGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852
Query: 426 DGR 428
+ R
Sbjct: 853 EAR 855
Score = 131 bits (317), Expect = 1e-29
Identities = 157/625 (25%), Positives = 254/625 (40%), Gaps = 54/625 (8%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V T + +P PP D+ V ++T + +TW D N + Y
Sbjct: 299 VAISSLGMIEATAQV---TVKALPK-PPIDLVVTETTATSVTLTW-----DSGNSEPVTY 349
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
Y G Q + + GP + V+G T +R ++ GL + YA V A NS
Sbjct: 350 Y-GIQYRAAGT-----EGP------FQEVDGVAT--TRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAP 325
E PS PP +Q LS+ ++ V WEPP NG+++GYRV Y P
Sbjct: 396 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP--EEPNGLVRGYRVYYTP 453
Query: 326 VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
+ N +GL TT+ L YS+ V AFTA GDG + + T++ VP+
Sbjct: 454 DSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA 513
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
PAD +A V S +I +SWL P P ++ Y L ED E+ HK P T S+
Sbjct: 514 QPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAED--EDQQHKVTFDP-TSSYT 568
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWK 498
P ++F ++A + +G G T + + S P+ ++ S + W
Sbjct: 569 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 628
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL--TISMTQSADSGNYTCSVE 556
+ S N V ++G + +S + + + + + + + +
Sbjct: 629 PPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHT 688
Query: 557 NIHGRDE---VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINY 610
++ E V + VP PP V+ + ++H+ W I GY + Y
Sbjct: 689 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTY 748
Query: 611 KR-EHGDWEELQV-----EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
R E+G+ L + A E + L T Y + + A+ G G T
Sbjct: 749 VRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT 808
Query: 665 GTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
G VP +P T T + W G +L + ++Y + + + +
Sbjct: 809 GAVPGRPTMMISTTAMNTALLQWHPPKELPG-ELLGYRLQYCRADEARPNTI--DFGKDD 865
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ F+V+GL Y R+ A N AG
Sbjct: 866 QHFTVTGLHKGTTYIFRLAAKNRAG 890
Score = 130 bits (314), Expect = 3e-29
Identities = 164/704 (23%), Positives = 283/704 (40%), Gaps = 58/704 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P ++ V + + ++ ++W +GNS P+ Y +QY+ A P + +
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQEVDGV---AT 371
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y R++A N +G+ PS+ V+ T E+ PS PP+ V+ S++ ++
Sbjct: 372 TRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTML 431
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WEPP+ NG + GY V + + P A + T G TT+
Sbjct: 432 VQWEPPEEP--NGLVRGYRVYYTPDSRR--------PPNAWHKHNTDAGL-----LTTVG 476
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y++ V A+ + + VP+ P Q S +++SW P
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLLP 535
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
P + I+ Y + Y D + VT + + TL L+ T Y + A + G
Sbjct: 536 P---QERIIM-YELVYWAAED-EDQQHKVTFDPTSSY-TLEDLKPDTLYRFQLAARSDMG 589
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVS-SRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
GV + T + PSAP VS + VSW+PP S NGV+ Y++ +
Sbjct: 590 VGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 649
Query: 425 EDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
DG + G H +S S + ++ WV A T +G G + V V + VP
Sbjct: 650 -DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 708
Query: 484 A------RITSFSRNIV-TPWKENI-SLSCNKVGVPAPATTWTMNGV--GLESTLRKNVS 533
+ + + V WK + S ++ NG GL ++
Sbjct: 709 SGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA 768
Query: 534 SDGTLTIS-----MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
TIS T S YT + + ++ T VP +P ++ + +
Sbjct: 769 EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA-VPGRPTMMISTTAMNTA 827
Query: 589 LHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
L LQW + +LGY + Y R + + + L GT Y + A
Sbjct: 828 L-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAK 886
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS--WGDGGCGILYFVIEY 705
NR G G + + P++ + L T+T + D + I+ + + +
Sbjct: 887 NRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF 946
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
R+++ Q + N T+ F+++GL P Y +++ A + G
Sbjct: 947 RDINSQQ--ELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKG 986
Score = 113 bits (271), Expect = 4e-24
Identities = 101/378 (26%), Positives = 156/378 (41%), Gaps = 24/378 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 596 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 653
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 654 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 713
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTV 234
V VE +ST + V W+ P +G I GY V + L + P G ++ V
Sbjct: 714 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-------PRGLP-IIQDV 765
Query: 235 EGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA 294
A TT+SGL Y+V V AY ++ VP P + A
Sbjct: 766 MLA--EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTA 823
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
++ + + W PP + G L GYR+ Y + N K H T++GL + T
Sbjct: 824 MN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGLHKGT 877
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPN 411
Y + A AG G T ED+PS P ++ + + ++W PP + N
Sbjct: 878 TYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 936
Query: 412 GVLVGYTLYMSVIEDGRE 429
G ++ YT+ I +E
Sbjct: 937 GRIISYTVVFRDINSQQE 954
Score = 90.6 bits (215), Expect = 3e-17
Identities = 87/375 (23%), Positives = 142/375 (37%), Gaps = 30/375 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKV--IVPGSVT 128
P+ + V S + + W P + I Y V Y P + ++
Sbjct: 712 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 771
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++
Sbjct: 772 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LL 829
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W PP+ G +LGY + + + I G +TV +G
Sbjct: 830 QWHPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TG 872
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L K Y + A N R ED+PS P L L++ + ++W+PP
Sbjct: 873 LHKGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 931
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+ RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G
Sbjct: 932 LAERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGS 987
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIED 426
G + + T + + A + + +L+SW P S + LY SV D
Sbjct: 988 GPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVD 1047
Query: 427 GREEGTHKRMLSPST 441
G L P+T
Sbjct: 1048 GHSMRKLIADLQPNT 1062
Score = 82.2 bits (194), Expect = 9e-15
Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 12/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++L+C VG P P W M G E +++ G + ++ S NYTC +
Sbjct: 248 SVNLTCVAVGAPMPYVKWMM---GAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSL 304
Query: 560 GRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR--EHGD 616
G E T V VK P+PPI L V ++ A S+ L W D G+ P+ Y I Y+ G
Sbjct: 305 GMIEATAQVTVKALPKPPIDLVVTETTATSVTLTW-DSGN-SEPVTYYGIQYRAAGTEGP 362
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
++E+ A T+ + + L + Y + A N IG G P + V A T P P+ Q
Sbjct: 363 FQEVDGVA-TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQ 421
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ +T+ V W G Y V + +P ++ A + +V L P
Sbjct: 422 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDA-GLLTTVGSLLP 480
Query: 735 AAHYQLRITAHNNAG 749
Y LR+ A G
Sbjct: 481 GITYSLRVLAFTAVG 495
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 148 bits (359), Expect = 9e-35
Identities = 104/363 (28%), Positives = 162/363 (44%), Gaps = 21/363 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 565
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 566 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 625
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 673
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 674 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 733
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI---SGLHTTLSGLRRYTNYSVTVCAFTA 365
++G ++GY+VTY + + + + + TT+SGL T YSVTV A+T
Sbjct: 734 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTT 793
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
GDG R+ P T VP P + + ++ N L+ W PP G L+GY L +
Sbjct: 794 KGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852
Query: 426 DGR 428
+ R
Sbjct: 853 EAR 855
Score = 131 bits (317), Expect = 1e-29
Identities = 157/625 (25%), Positives = 254/625 (40%), Gaps = 54/625 (8%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V T + +P PP D+ V ++T + +TW D N + Y
Sbjct: 299 VAISSLGMIEATAQV---TVKALPK-PPIDLVVTETTATSVTLTW-----DSGNSEPVTY 349
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
Y G Q + + GP + V+G T +R ++ GL + YA V A NS
Sbjct: 350 Y-GIQYRAAGT-----EGP------FQEVDGVAT--TRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAP 325
E PS PP +Q LS+ ++ V WEPP NG+++GYRV Y P
Sbjct: 396 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP--EEPNGLVRGYRVYYTP 453
Query: 326 VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
+ N +GL TT+ L YS+ V AFTA GDG + + T++ VP+
Sbjct: 454 DSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA 513
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
PAD +A V S +I +SWL P P ++ Y L ED E+ HK P T S+
Sbjct: 514 QPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAED--EDQQHKVTFDP-TSSYT 568
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWK 498
P ++F ++A + +G G T + + S P+ ++ S + W
Sbjct: 569 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 628
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL--TISMTQSADSGNYTCSVE 556
+ S N V ++G + +S + + + + + + + +
Sbjct: 629 PPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHT 688
Query: 557 NIHGRDE---VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINY 610
++ E V + VP PP V+ + ++H+ W I GY + Y
Sbjct: 689 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTY 748
Query: 611 KR-EHGDWEELQV-----EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
R E+G+ L + A E + L T Y + + A+ G G T
Sbjct: 749 VRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT 808
Query: 665 GTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
G VP +P T T + W G +L + ++Y + + + +
Sbjct: 809 GAVPGRPTMMISTTAMNTALLQWHPPKELPG-ELLGYRLQYCRADEARPNTI--DFGKDD 865
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ F+V+GL Y R+ A N AG
Sbjct: 866 QHFTVTGLHKGTTYIFRLAAKNRAG 890
Score = 130 bits (314), Expect = 3e-29
Identities = 164/704 (23%), Positives = 283/704 (40%), Gaps = 58/704 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P ++ V + + ++ ++W +GNS P+ Y +QY+ A P + +
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQEVDGV---AT 371
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y R++A N +G+ PS+ V+ T E+ PS PP+ V+ S++ ++
Sbjct: 372 TRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTML 431
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WEPP+ NG + GY V + + P A + T G TT+
Sbjct: 432 VQWEPPEEP--NGLVRGYRVYYTPDSRR--------PPNAWHKHNTDAGL-----LTTVG 476
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y++ V A+ + + VP+ P Q S +++SW P
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLLP 535
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
P + I+ Y + Y D + VT + + TL L+ T Y + A + G
Sbjct: 536 P---QERIIM-YELVYWAAED-EDQQHKVTFDPTSSY-TLEDLKPDTLYRFQLAARSDMG 589
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVS-SRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
GV + T + PSAP VS + VSW+PP S NGV+ Y++ +
Sbjct: 590 VGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 649
Query: 425 EDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
DG + G H +S S + ++ WV A T +G G + V V + VP
Sbjct: 650 -DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 708
Query: 484 A------RITSFSRNIV-TPWKENI-SLSCNKVGVPAPATTWTMNGV--GLESTLRKNVS 533
+ + + V WK + S ++ NG GL ++
Sbjct: 709 SGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA 768
Query: 534 SDGTLTIS-----MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
TIS T S YT + + ++ T VP +P ++ + +
Sbjct: 769 EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA-VPGRPTMMISTTAMNTA 827
Query: 589 LHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
L LQW + +LGY + Y R + + + L GT Y + A
Sbjct: 828 L-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAK 886
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS--WGDGGCGILYFVIEY 705
NR G G + + P++ + L T+T + D + I+ + + +
Sbjct: 887 NRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF 946
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
R+++ Q + N T+ F+++GL P Y +++ A + G
Sbjct: 947 RDINSQQ--ELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKG 986
Score = 113 bits (271), Expect = 4e-24
Identities = 101/378 (26%), Positives = 156/378 (41%), Gaps = 24/378 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 596 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 653
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 654 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 713
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTV 234
V VE +ST + V W+ P +G I GY V + L + P G ++ V
Sbjct: 714 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-------PRGLP-IIQDV 765
Query: 235 EGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA 294
A TT+SGL Y+V V AY ++ VP P + A
Sbjct: 766 MLA--EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTA 823
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
++ + + W PP + G L GYR+ Y + N K H T++GL + T
Sbjct: 824 MN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGLHKGT 877
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPN 411
Y + A AG G T ED+PS P ++ + + ++W PP + N
Sbjct: 878 TYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 936
Query: 412 GVLVGYTLYMSVIEDGRE 429
G ++ YT+ I +E
Sbjct: 937 GRIISYTVVFRDINSQQE 954
Score = 90.6 bits (215), Expect = 3e-17
Identities = 87/375 (23%), Positives = 142/375 (37%), Gaps = 30/375 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKV--IVPGSVT 128
P+ + V S + + W P + I Y V Y P + ++
Sbjct: 712 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 771
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++
Sbjct: 772 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LL 829
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W PP+ G +LGY + + + I G +TV +G
Sbjct: 830 QWHPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TG 872
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L K Y + A N R ED+PS P L L++ + ++W+PP
Sbjct: 873 LHKGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 931
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+ RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G
Sbjct: 932 LAERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGS 987
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIED 426
G + + T + + A + + +L+SW P S + LY SV D
Sbjct: 988 GPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVD 1047
Query: 427 GREEGTHKRMLSPST 441
G L P+T
Sbjct: 1048 GHSMRKLIADLQPNT 1062
Score = 82.2 bits (194), Expect = 9e-15
Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 12/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++L+C VG P P W M G E +++ G + ++ S NYTC +
Sbjct: 248 SVNLTCVAVGAPMPYVKWMM---GAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSL 304
Query: 560 GRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR--EHGD 616
G E T V VK P+PPI L V ++ A S+ L W D G+ P+ Y I Y+ G
Sbjct: 305 GMIEATAQVTVKALPKPPIDLVVTETTATSVTLTW-DSGN-SEPVTYYGIQYRAAGTEGP 362
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
++E+ A T+ + + L + Y + A N IG G P + V A T P P+ Q
Sbjct: 363 FQEVDGVA-TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQ 421
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ +T+ V W G Y V + +P ++ A + +V L P
Sbjct: 422 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDA-GLLTTVGSLLP 480
Query: 735 AAHYQLRITAHNNAG 749
Y LR+ A G
Sbjct: 481 GITYSLRVLAFTAVG 495
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 148 bits (359), Expect = 9e-35
Identities = 104/363 (28%), Positives = 162/363 (44%), Gaps = 21/363 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 531 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 585
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 586 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 645
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 646 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 693
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 694 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 753
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI---SGLHTTLSGLRRYTNYSVTVCAFTA 365
++G ++GY+VTY + + + + + TT+SGL T YSVTV A+T
Sbjct: 754 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTT 813
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
GDG R+ P T VP P + + ++ N L+ W PP G L+GY L +
Sbjct: 814 KGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 872
Query: 426 DGR 428
+ R
Sbjct: 873 EAR 875
Score = 131 bits (317), Expect = 1e-29
Identities = 157/625 (25%), Positives = 254/625 (40%), Gaps = 54/625 (8%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V T + +P PP D+ V ++T + +TW D N + Y
Sbjct: 319 VAISSLGMIEATAQV---TVKALPK-PPIDLVVTETTATSVTLTW-----DSGNSEPVTY 369
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
Y G Q + + GP + V+G T +R ++ GL + YA V A NS
Sbjct: 370 Y-GIQYRAAGT-----EGP------FQEVDGVAT--TRYSIGGLSPFSEYAFRVLAVNSI 415
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAP 325
E PS PP +Q LS+ ++ V WEPP NG+++GYRV Y P
Sbjct: 416 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP--EEPNGLVRGYRVYYTP 473
Query: 326 VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
+ N +GL TT+ L YS+ V AFTA GDG + + T++ VP+
Sbjct: 474 DSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA 533
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
PAD +A V S +I +SWL P P ++ Y L ED E+ HK P T S+
Sbjct: 534 QPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAED--EDQQHKVTFDP-TSSYT 588
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWK 498
P ++F ++A + +G G T + + S P+ ++ S + W
Sbjct: 589 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 648
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL--TISMTQSADSGNYTCSVE 556
+ S N V ++G + +S + + + + + + + +
Sbjct: 649 PPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHT 708
Query: 557 NIHGRDE---VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINY 610
++ E V + VP PP V+ + ++H+ W I GY + Y
Sbjct: 709 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTY 768
Query: 611 KR-EHGDWEELQV-----EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
R E+G+ L + A E + L T Y + + A+ G G T
Sbjct: 769 VRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT 828
Query: 665 GTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
G VP +P T T + W G +L + ++Y + + + +
Sbjct: 829 GAVPGRPTMMISTTAMNTALLQWHPPKELPG-ELLGYRLQYCRADEARPNTI--DFGKDD 885
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ F+V+GL Y R+ A N AG
Sbjct: 886 QHFTVTGLHKGTTYIFRLAAKNRAG 910
Score = 130 bits (314), Expect = 3e-29
Identities = 164/704 (23%), Positives = 283/704 (40%), Gaps = 58/704 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P ++ V + + ++ ++W +GNS P+ Y +QY+ A P + +
Sbjct: 338 LPKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQEVDGV---AT 391
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y R++A N +G+ PS+ V+ T E+ PS PP+ V+ S++ ++
Sbjct: 392 TRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTML 451
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WEPP+ NG + GY V + + P A + T G TT+
Sbjct: 452 VQWEPPEEP--NGLVRGYRVYYTPDSRR--------PPNAWHKHNTDAGL-----LTTVG 496
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y++ V A+ + + VP+ P Q S +++SW P
Sbjct: 497 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLLP 555
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
P + I+ Y + Y D + VT + + TL L+ T Y + A + G
Sbjct: 556 P---QERIIM-YELVYWAAED-EDQQHKVTFDPTSSY-TLEDLKPDTLYRFQLAARSDMG 609
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVS-SRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
GV + T + PSAP VS + VSW+PP S NGV+ Y++ +
Sbjct: 610 VGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 669
Query: 425 EDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
DG + G H +S S + ++ WV A T +G G + V V + VP
Sbjct: 670 -DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 728
Query: 484 A------RITSFSRNIV-TPWKENI-SLSCNKVGVPAPATTWTMNGV--GLESTLRKNVS 533
+ + + V WK + S ++ NG GL ++
Sbjct: 729 SGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA 788
Query: 534 SDGTLTIS-----MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
TIS T S YT + + ++ T VP +P ++ + +
Sbjct: 789 EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA-VPGRPTMMISTTAMNTA 847
Query: 589 LHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
L LQW + +LGY + Y R + + + L GT Y + A
Sbjct: 848 L-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAK 906
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS--WGDGGCGILYFVIEY 705
NR G G + + P++ + L T+T + D + I+ + + +
Sbjct: 907 NRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF 966
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
R+++ Q + N T+ F+++GL P Y +++ A + G
Sbjct: 967 RDINSQQ--ELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKG 1006
Score = 113 bits (271), Expect = 4e-24
Identities = 101/378 (26%), Positives = 156/378 (41%), Gaps = 24/378 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 616 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 673
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 674 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 733
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTV 234
V VE +ST + V W+ P +G I GY V + L + P G ++ V
Sbjct: 734 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-------PRGLP-IIQDV 785
Query: 235 EGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA 294
A TT+SGL Y+V V AY ++ VP P + A
Sbjct: 786 MLA--EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTA 843
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
++ + + W PP + G L GYR+ Y + N K H T++GL + T
Sbjct: 844 MN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGLHKGT 897
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPN 411
Y + A AG G T ED+PS P ++ + + ++W PP + N
Sbjct: 898 TYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 956
Query: 412 GVLVGYTLYMSVIEDGRE 429
G ++ YT+ I +E
Sbjct: 957 GRIISYTVVFRDINSQQE 974
Score = 90.6 bits (215), Expect = 3e-17
Identities = 87/375 (23%), Positives = 142/375 (37%), Gaps = 30/375 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKV--IVPGSVT 128
P+ + V S + + W P + I Y V Y P + ++
Sbjct: 732 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 791
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++
Sbjct: 792 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LL 849
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W PP+ G +LGY + + + I G +TV +G
Sbjct: 850 QWHPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TG 892
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L K Y + A N R ED+PS P L L++ + ++W+PP
Sbjct: 893 LHKGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 951
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+ RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G
Sbjct: 952 LAERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGS 1007
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIED 426
G + + T + + A + + +L+SW P S + LY SV D
Sbjct: 1008 GPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVD 1067
Query: 427 GREEGTHKRMLSPST 441
G L P+T
Sbjct: 1068 GHSMRKLIADLQPNT 1082
Score = 82.2 bits (194), Expect = 9e-15
Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 12/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++L+C VG P P W M G E +++ G + ++ S NYTC +
Sbjct: 268 SVNLTCVAVGAPMPYVKWMM---GAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSL 324
Query: 560 GRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR--EHGD 616
G E T V VK P+PPI L V ++ A S+ L W D G+ P+ Y I Y+ G
Sbjct: 325 GMIEATAQVTVKALPKPPIDLVVTETTATSVTLTW-DSGN-SEPVTYYGIQYRAAGTEGP 382
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
++E+ A T+ + + L + Y + A N IG G P + V A T P P+ Q
Sbjct: 383 FQEVDGVA-TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQ 441
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ +T+ V W G Y V + +P ++ A + +V L P
Sbjct: 442 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDA-GLLTTVGSLLP 500
Query: 735 AAHYQLRITAHNNAG 749
Y LR+ A G
Sbjct: 501 GITYSLRVLAFTAVG 515
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 147 bits (357), Expect = 2e-34
Identities = 115/396 (29%), Positives = 176/396 (44%), Gaps = 33/396 (8%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+++SW+ N+PI Y +++++ AP W S + VPG+ TS +++ L P Y
Sbjct: 626 VRVSWSPAEDHNAPIEKYDIEFEDKEMAPGKWYSLGK---VPGNQTSTTLK-LSPYVHYT 681
Query: 143 LRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
R+ A N+ G EPS PV V T E P P DV+ E +T +++TW+P + WN
Sbjct: 682 FRVTAINKYGPGEPS-PVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 740
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y V ++ + GP + + V S T+ Y + VQ
Sbjct: 741 PQVQYRVQWRPQGTR-------GP----WQEQIVSDPFLVVSNTST-----FVPYEIKVQ 784
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A NS+ ED P P L+S +V V W P + G L+GY
Sbjct: 785 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 844
Query: 321 VTY------APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
VTY + + ++D V + LSGLR Y++Y + V AF G G A+
Sbjct: 845 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASE 903
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK 434
T E VP P + S +L+ W PP S NGVL GY L +++G +
Sbjct: 904 FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSF 963
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+ P +H + P ++F + A+T+ G GEA
Sbjct: 964 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 999
Score = 50.8 bits (116), Expect = 3e-05
Identities = 64/281 (22%), Positives = 105/281 (37%), Gaps = 20/281 (7%)
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPA--PATTWTMNGVGLEST--LRKNVSSDGTLTI 540
+IT R+ + ++ +C P+ P+ TW +G L+ K DG L I
Sbjct: 514 QITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 573
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY---ADSLHLQWSDQ 596
+D GNY+C E + V P P P L + D + + + WS
Sbjct: 574 HSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPA 633
Query: 597 GDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
D +PI Y I ++ + G W L G L Y +TA N+ G G
Sbjct: 634 EDHNAPIEKYDIEFEDKEMAPGKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPG 693
Query: 654 LPCDIVH-AYTKGTVPVKPKHSQMITLNTTT--VTVWLD-SWGDGGCGILYFVIEYR-EM 708
P + T P K N TT V W W D + + +++R +
Sbjct: 694 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 753
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ W+ ++ VS + Y++++ A N+ G
Sbjct: 754 TRGPWQ----EQIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 790
Score = 44.4 bits (100), Expect = 0.002
Identities = 81/385 (21%), Positives = 150/385 (38%), Gaps = 34/385 (8%)
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
+++++ VSW P N + Y + E + + P + T + P +
Sbjct: 622 TQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPGKWYSLGKV-PGNQTSTTLKLSPYVHY 680
Query: 456 QFWVSASTRLGEGEATRVV-TVLPSDSVPARIT-------SFSRNIVTPWKENISLSCNK 507
F V+A + G GE + V TV+ ++ P + + + N+V WK + N
Sbjct: 681 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 740
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD---EV 564
V W G ++ + SD L +S T + N G+ +V
Sbjct: 741 PQVQY-RVQWRPQGT--RGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 797
Query: 565 TYTVEVKVPPQ--PPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKRE------- 613
T + PQ P + + + ++ ++W D + GY + Y RE
Sbjct: 798 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 857
Query: 614 --HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
H + + V A T+ +L L + Y L + AFN G+G + + +G VP P
Sbjct: 858 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPGHP 916
Query: 672 KHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVFSV 729
+ + NT+ + W G + +V+ Y + + +S +++ E R ++
Sbjct: 917 EALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNL 975
Query: 730 SGLTPAAHY--QLRITAHNNAGHAL 752
+ L+P Y QL+ T G A+
Sbjct: 976 TDLSPHLRYRFQLQATTKEGPGEAI 1000
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVE 556
E L C G P P TW +NG+ +E + K G L +S Q +D+ C
Sbjct: 343 ETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEAR 402
Query: 557 NIHG 560
N HG
Sbjct: 403 NRHG 406
Score = 35.9 bits (79), Expect = 0.80
Identities = 22/88 (25%), Positives = 33/88 (37%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
T+ S ++V + + L C G P P W + + + + TL +
Sbjct: 241 TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNHNKTLQLLKVGEE 300
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C EN G Y V V+ P
Sbjct: 301 DDGEYRCLAENSLGSARHAYYVTVEAAP 328
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 482 VPARI-TSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLT 539
+PA+I T+ ++ + L C G P P+ W +G + R ++GTL
Sbjct: 419 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 478
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
I Q+ D+G Y C N ++ VT +KV
Sbjct: 479 IRDLQANDTGRYFCLAAN--DQNNVTIMANLKV 509
>X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 1523
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 126 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 179
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 180 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 239
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 240 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 287
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 288 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 347
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 348 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 407
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 408 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 466
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 467 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 521
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 522 ISIP-EEVP---TGFPQNL 536
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 24 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 83
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 84 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 141
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 142 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 181
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 182 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 241
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 242 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 297
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 298 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 357
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 358 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 417
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 418 GDGARSKPKLVSTTGAVPGK 437
Score = 117 bits (282), Expect = 2e-25
Identities = 142/635 (22%), Positives = 254/635 (40%), Gaps = 54/635 (8%)
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++V W+ P+ NG I
Sbjct: 3 RVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP--NGQIQ 60
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
GY V + ++ V ++ V + TT+ L Y+V V A+
Sbjct: 61 GYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIGNLVPQKTYSVKVLAFT 107
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S VP P + S S+ +SW PP R+ + Y + Y
Sbjct: 108 SIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP----RSDTIANYELVY 162
Query: 324 APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV 383
+G E +T + G L GL+ + Y + A + G G A + T +
Sbjct: 163 KDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 219
Query: 384 PSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPS 440
PSAP DI S ILVSW PP NG++ Y++ + + DG ++ H+ + PS
Sbjct: 220 PSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV-DGEDDKPHEILGIPS 278
Query: 441 -TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV---PARITSF----SRN 492
T + + ++ V+A T +G G + V + ++ V P R S +
Sbjct: 279 DTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS 338
Query: 493 IVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV-----------SSDGTLTI 540
+ W+ + + ++ NG + K+V +++ + I
Sbjct: 339 VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMII 398
Query: 541 SMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQG 597
S Q S + T + G R + P P L + + ++ +QW
Sbjct: 399 SGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPV 458
Query: 598 DGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG--L 654
D P+ GY + + R+ + L+ ++ G Y ++A N++G G +
Sbjct: 459 DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEM 518
Query: 655 PCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWR 714
+I T + HS+ T + ++ + I + + YR+++ P
Sbjct: 519 VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLP 578
Query: 715 LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ V A + +++GL P Y +++ AH + G
Sbjct: 579 MEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 612
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 208 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 266
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 267 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 326
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 327 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 385
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 386 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 443
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 444 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 497
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 498 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 557
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 558 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 615
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 616 YSPSVQFRTLPVDQVFAK 633
Score = 37.9 bits (84), Expect = 0.20
Identities = 60/248 (24%), Positives = 94/248 (37%), Gaps = 19/248 (7%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNK 507
+F V A +G G + V S+ P AR+ S S I+ WKE +
Sbjct: 1 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQI 59
Query: 508 VGVPAPAT---TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
G T T +N + +++ G L T S +T S+ + ++
Sbjct: 60 QGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDI 118
Query: 565 TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVE 623
+ VP QP S+ L W+ I Y + YK EHG+ + + +E
Sbjct: 119 QVITQTGVPGQPLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIE 176
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTT 683
GTS + L L + Y + A + G G + A T + P P Q I+ + +
Sbjct: 177 PGTS-YRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPS 233
Query: 684 VTVWLDSW 691
T L SW
Sbjct: 234 STSILVSW 241
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.4 bits (110), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 147 bits (355), Expect = 3e-34
Identities = 123/439 (28%), Positives = 195/439 (44%), Gaps = 42/439 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N + + +I +SWT P + I NY + YK+ + I PG T
Sbjct: 515 VPGQPLNFKAEPESETSILLSWTPPRSDT--IANYELVYKDGEHG--EEQRITIEPG--T 568
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S +Q L+P + Y+ R+ A + G + + T + PS PPQD+ + SST ++V
Sbjct: 569 SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILV 628
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W+PP + NG I Y + + ++ G + G + ++ L
Sbjct: 629 SWQPPPVEKQNGIITEYSIKYTAVD------------GEDDKPHEILGIPSDTTKYLLEQ 676
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + V A+ EDVPS PP ++ A++S SV+VSW P
Sbjct: 677 LEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPV 736
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-------HTT-----LSGLRRYTNY 356
++G ++GY+V Y + + + K + TT +SGL+ T+Y
Sbjct: 737 PNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSY 796
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
S+TV A+T GDG R+ P T VP P + + N L+ W PP G L G
Sbjct: 797 SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 855
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTL-SHETSRSPPR-ATHQFWVSASTRLGEGEATRVV 474
Y L + GR++ L S H T+ + A++ F +SA ++G GE
Sbjct: 856 YRL-----KFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE 910
Query: 475 TVLPSDSVPARITSFSRNI 493
+P + VP T F +N+
Sbjct: 911 ISIP-EEVP---TGFPQNL 925
Score = 145 bits (352), Expect = 7e-34
Identities = 120/440 (27%), Positives = 194/440 (44%), Gaps = 46/440 (10%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++++W PP+ D I Y + +++ I P G SY
Sbjct: 531 SILLSWTPPRSD----TIANYELVYKDGEHGEEQRITIEP-GTSY--------------- 570
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+ ++ Y + A + + M+ PS PP + C + SS S+ VSW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTT---LSGLRRYTNYSVT 359
+PPP+ +NGI+ Y + Y V ED +I G+ TT L L ++T Y +T
Sbjct: 631 QPPPVEKQNGIITEYSIKYTAV----DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRIT 686
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLP--PSSPNGVLVG 416
V A T G G + V T EDVPS P ++ + + VSW P+ +G + G
Sbjct: 687 VTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRG 746
Query: 417 YTLYMSVIEDGREEG---THKRMLSPS------TLSHE--TSRSPPRATHQFWVSASTRL 465
Y ++ +E+G +G ML+ + T H+ S P ++ V+A T
Sbjct: 747 YQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTK 806
Query: 466 GEGEATRVVTVLPSDSVPAR 485
G+G ++ V + +VP +
Sbjct: 807 GDGARSKPKLVSTTGAVPGK 826
Score = 138 bits (333), Expect = 1e-31
Identities = 163/711 (22%), Positives = 290/711 (40%), Gaps = 61/711 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADSQI----TTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYKDGE--HGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPA-DIKAAVSSRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
G A + T + PSAP DI S ILVSW PP NG++ Y++ + +
Sbjct: 593 LGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAV 652
Query: 425 EDGREEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG ++ H+ + PS T + + ++ V+A T +G G + V + ++ V
Sbjct: 653 -DGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVP 711
Query: 483 --PARITSF----SRNIVTPWKENI-SLSCNKVGVPAPATTWTMNGVGLESTLRKNV--- 532
P R S ++ W+ + + ++ NG + K+V
Sbjct: 712 SGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA 771
Query: 533 --------SSDGTLTISMTQSADSGNYTCSVENIHG---RDEVTYTVEVKVPPQPPILAV 581
+++ + IS Q S + T + G R + P P L +
Sbjct: 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVI 831
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRY 640
+ ++ +QW D P+ GY + + R+ + L+ ++ G Y
Sbjct: 832 NHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASY 891
Query: 641 QLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
++A N++G G + +I T + HS+ T + ++ + I
Sbjct: 892 VFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGII 951
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + YR+++ P + V A + +++GL P Y +++ AH + G
Sbjct: 952 TKYTLLYRDINIPLLPMEQLIVPA-DTTMTLTGLKPDTTYDVKVRAHTSKG 1001
Score = 113 bits (271), Expect = 4e-24
Identities = 106/438 (24%), Positives = 174/438 (39%), Gaps = 21/438 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T ++ ++ + P++I S +I +SW P N I Y ++Y A +
Sbjct: 597 TAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT-AVDGE 655
Query: 115 PSTPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP 173
P +++ +P T ++ L+ T Y + + A +G S V + T E+VPSGPP
Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPP 715
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ V VEA +ST + V+W P + +G I GY V + + N
Sbjct: 716 RKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRM-ENGEPKGQPMLKDVMLADAQ 774
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
E T +SGLQ +Y++ V AY ++ VP P L N
Sbjct: 775 WEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKP--RLVIN 832
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL--HTTLSGLR 351
+ + W PP G LQGYR+ + E T + S H T + +
Sbjct: 833 HTQMNTALIQWHPPV--DTFGPLQGYRLKFGR----KDMEPLTTLEFSEKEDHFTATDIH 886
Query: 352 RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP--SS 409
+ +Y + A G G EE P ++ + ++ + +SW PP +
Sbjct: 887 KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAE 946
Query: 410 PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG++ YTL I ++++ P+ + + P T+ V A T G G
Sbjct: 947 RNGIITKYTLLYRDINIPLL--PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGP 1004
Query: 470 ATRVV--TVLPSDSVPAR 485
+ V LP D V A+
Sbjct: 1005 YSPSVQFRTLPVDQVFAK 1022
Score = 106 bits (255), Expect = 4e-22
Identities = 147/616 (23%), Positives = 237/616 (38%), Gaps = 61/616 (9%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKPLPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G G +T ++ S P+ + S +I+ W+ N +
Sbjct: 590 PQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKY 649
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---- 571
++G + + SD T + + T + G + +V ++
Sbjct: 650 TAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Query: 572 VPPQPPILAVVDSY-ADSLHLQWSD--QGDGGSPILGYVINYKR-EHGD----------- 616
VP PP V++ + S+ + W I GY ++Y R E+G+
Sbjct: 710 VPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVM 769
Query: 617 WEELQVE-AGTSEH--VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH 673
+ Q E T+EH ++ L T Y L +TA+ G G T G VP KP+
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL 829
Query: 674 SQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
T T + W G Y + R+ +P L + E F+ + +
Sbjct: 830 VINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEP---LTTLEFSEKEDHFTATDIH 886
Query: 734 PAAHYQLRITAHNNAG 749
A Y R++A N G
Sbjct: 887 KGASYVFRLSARNKVG 902
Score = 76.2 bits (179), Expect = 6e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKPLPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 48.8 bits (111), Expect = 1e-04
Identities = 83/357 (23%), Positives = 136/357 (38%), Gaps = 29/357 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKPLPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ Y + A + G G + A T + P P Q I+ + + T L SW
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAP--PQDISCTSPSSTSILVSW 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 146 bits (354), Expect = 4e-34
Identities = 159/698 (22%), Positives = 265/698 (37%), Gaps = 44/698 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P RV+D +I ++WT+P Y G + I+ Y+++ +E + W +
Sbjct: 22845 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRN-- 22902
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +L+ Y R+ A N G SE S+ + E P ++ + K + +
Sbjct: 22903 TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIR 22962
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G L V ++ +I G R + + S +
Sbjct: 22963 A-----------GASLRLMVS---VSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ ++ A ++A N + D P P +++ +S SV ++WE P
Sbjct: 23009 KVNRYDAGKYTIEAENQ---SGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIP 23064
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
+ G + Y V VT + S +SGL T Y V G
Sbjct: 23065 TIDG-GAPVNNYIVEKREAA--MRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG 23121
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIED 426
G +VP PA ++ +++ + ++W P G L GY L +
Sbjct: 23122 IGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL--EACKA 23179
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR- 485
G E L P+ L H + + F + A G E VT + +
Sbjct: 23180 GTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP 23239
Query: 486 ----ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTL 538
T + I P + L G P PA +W G L + R V + L
Sbjct: 23240 TIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKL 23299
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS-D 595
TI T D+G YT ++N+ G T V + P PP + + + A S+ + W
Sbjct: 23300 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP 23359
Query: 596 QGDGGSPILGYVINYKREH-GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG- 653
+ DGG+P+ GYV+ + H W + S L G Y + A NR G G
Sbjct: 23360 ELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 23419
Query: 654 -LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP 711
L +++ + +P P+ Q+ ++ +T+ W DGG + +++E +E+
Sbjct: 23420 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD 23479
Query: 712 QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V N V T + +GLT Y+ R+TA N G
Sbjct: 23480 RWVRV-NKVPVTMTRYRSTGLTEGLEYEHRVTAINARG 23516
Score = 137 bits (331), Expect = 2e-31
Identities = 161/666 (24%), Positives = 272/666 (40%), Gaps = 61/666 (9%)
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
E+ P + + + TS + + +I+ +N+ G++E ++V +VP G
Sbjct: 6539 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI---DVP-G 6594
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
P +++ V E+ + WE P D I+GY V +++ + VL +TV
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTD-GGSKIIGYVVERRDIKRKTWVLATDRAESCEFTV 6653
Query: 232 RTVEGAGTARSRTTLSGLQKHAA-YAVVVQAYN---SRXXXXXXXXXXXXXMEDVPSLPP 287
+GLQK Y V A N + DVP PP
Sbjct: 6654 ---------------TGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPG-PP 6697
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHT 345
+ ++ V ++WEPP G + Y + T W + A+T + L
Sbjct: 6698 LNVTITDVNRFGVSLTWEPPEYDG-GAEITNYVIELRDKTSIRW---DTAMTVRAEDLSA 6753
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV-RAAPVYCHTEEDV--PSAPADIKAAVSSRNKILV 402
T++ + YS V A G G AA + + + PS P ++ ++ +++ + +
Sbjct: 6754 TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQL 6813
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
W PP G ++GY + E+G++ M L+++ + + + VSA
Sbjct: 6814 KWEPPLKDGGSPILGYIIERC--EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSA 6871
Query: 462 STRLGEGEATRVVTVLPSDSV---PAR-ITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ G + + ++ L +D P +++F + I++ G P P TW
Sbjct: 6872 ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATW 6931
Query: 518 TMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV-- 572
LE+ R K +S+ L IS ++ +D G YT +EN ++ ++V V
Sbjct: 6932 CFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN--RVKTISGEIDVNVIA 6989
Query: 573 -PPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSE 628
P P L D DS+HL W DGGSP+ GYV+ KRE W ++ E
Sbjct: 6990 RPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE-KREVSRKTWTKVMDFVTDLE 7048
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQM--ITLNTTT 683
+P+L G Y + A N+ G G P + V+ T TVP P++ + T N+
Sbjct: 7049 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 7108
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
+T W DGG I +++E +W V T+ V+GL Y R+
Sbjct: 7109 LT-WDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETK--MEVTGLEEGKWYAYRVK 7165
Query: 744 AHNNAG 749
A N G
Sbjct: 7166 ALNRQG 7171
Score = 134 bits (323), Expect = 2e-30
Identities = 167/663 (25%), Positives = 267/663 (40%), Gaps = 51/663 (7%)
Query: 111 PESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
P + + K++V + T Q+ + T + I A N LG + + V P
Sbjct: 9666 PVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT-ITAVNNLGTASKEMRLNVLGRPGPPV 9724
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
GP ++ E+ S+ ++ ++W PP+ D I Y + +E N + V ++S P +YT
Sbjct: 9725 GP---IKFESVSADQMTLSWFPPKDD-GGSKITNYVIEKREANRKTWVHVSSEPKECTYT 9780
Query: 231 V-RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA 289
+ + +EG + ++ Q + VP P
Sbjct: 9781 IPKLLEG--------------HEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKP 9826
Query: 290 LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISGLHTT 346
++++ S+ V+WE P G + + GY + T W N D + G+
Sbjct: 9827 T-VSSVTRNSMTVNWEEPEYDGGSPVT-GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYK 9884
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSW 404
++GL ++Y V A AAG G + P T D P P K +++ + W
Sbjct: 9885 VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEW 9944
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
PP G V GY + E+G+EE + + A ++F VSA
Sbjct: 9945 SPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVN 10002
Query: 464 RLGEGEATRVVTVLPSD----SVPARITSFSRN-IVTPWKENISLSCNKVGVPAPATTWT 518
G GE V V+ S ++ + R+ IV I + G P P TW
Sbjct: 10003 IAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWN 10062
Query: 519 MNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP 576
MN L E+T+ S ++ I Q + G Y+ +N G + T V+V P P
Sbjct: 10063 MNERTLPQEATIETTAIS-SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGP 10121
Query: 577 ---PILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVL 631
P LA + +S L W S + DGGSPI YVI + + W + +
Sbjct: 10122 VGTPFLA-HNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATV 10180
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQM--ITLNTTTVTV 686
L G Y I A N IG G + A TVP +P+ ++ +T NT T+T
Sbjct: 10181 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT- 10239
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W DGG I+ +V+E R + ++ V+N R ++V GL Y+ R++A N
Sbjct: 10240 WNPPKYDGGSEIINYVLESRLIGTEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVN 10298
Query: 747 NAG 749
G
Sbjct: 10299 IVG 10301
Score = 132 bits (318), Expect = 9e-30
Identities = 161/707 (22%), Positives = 288/707 (40%), Gaps = 64/707 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
+P P +++D TI I+W +P + G +PI Y V+YK++ ++ W ++ Q +
Sbjct: 19586 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL----R 19641
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T ++ L Y R+ + N++G S+PS +E P D+ E + + L
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKT--L 19699
Query: 187 IV------TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
IV T P R N+L + + + + + S T+ +
Sbjct: 19700 IVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSG 19756
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ T+ + A+ +VV+ D P PP + ++ +S
Sbjct: 19757 KYTLTIQNVLSAASLTLVVKVL------------------DTPG-PPTNITVQDVTKESA 19797
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
+SW+ P G ++ Y + + W +VT + L ++ L+ Y
Sbjct: 19798 VLSWDVPENDG-GAPVKNYHIEKREASKKAWV----SVTNNCNRLSYKVTNLQEGAIYYF 19852
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V G G+ A + PS P + S++ + ++WL P G + +
Sbjct: 19853 RVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHY 19912
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VL 477
+ + +E G++ K ++ ST H S + + F V A + G + ++ VL
Sbjct: 19913 V-VEALEKGQKNWV-KCAVAKST-HHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 19969
Query: 478 PSDSV-PARIT--SF-SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+ + P I +F S + N+ + G P P T + +GV L++T+R N
Sbjct: 19970 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 20029
Query: 534 SDG-TLTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADS 588
LTI++ +S AD+G Y + N G + + V P PP VV D +S
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 20089
Query: 589 LHLQWS-DQGDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
+ L+W + DGGS + Y++ KRE W E+ + + L G YQ I
Sbjct: 20090 VTLKWEPPKYDGGSQVTNYIL-LKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIK 20148
Query: 646 AFNRIGTGLPCDIVHAYTK--GTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFV 702
A NR G D K T P P + + ++TV W + +GG ++ +
Sbjct: 20149 AENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYH 20208
Query: 703 IEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E ++ + W+ + V T F V+ ++ Y+ R+ A N AG
Sbjct: 20209 LEMKDRNSILWQKANKLVIRTTH-FKVTTISAGLIYEFRVYAENAAG 20254
Score = 128 bits (309), Expect = 1e-28
Identities = 162/706 (22%), Positives = 281/706 (39%), Gaps = 54/706 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P V D +++++WT+P + G + I +Y+++ K + W + V
Sbjct: 7487 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV----PT 7542
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSSTE 185
T + L Y R+ A N+ G+SEPS+P E P PP+ + V +
Sbjct: 7543 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7602
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ W P++D I Y V +++ + + TV+ ++ T
Sbjct: 7603 ADLKWTVPEKD-GGSPITNYIVEKRDVRRKGWQTVDT-------TVKD--------TKCT 7646
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVS 303
++ L + + Y V A N+ +D + P P AL ++ + V +
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 7706
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVC 361
WEPP G I Q Y + + G + +G + ++ + T V
Sbjct: 7707 WEPPKNDGGRPI-QRYVIEKK---ERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVR 7762
Query: 362 AFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGY 417
A AG G + P + ED PS P D+ + R I ++W PP G ++GY
Sbjct: 7763 AENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV---V 474
+ M + + + R + E P + + V A +G E + + V
Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK-EYVLRVRAVNAIGVSEPSEISENV 7881
Query: 475 TVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS 534
D P I + +I+ E +S+ VP P +W +G ++++ R + +
Sbjct: 7882 VAKDPDCKPT-IDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN 7940
Query: 535 D---GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSYADSLH 590
D L + + AD+G YT ++EN G + V+V P P + D S
Sbjct: 7941 DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8000
Query: 591 LQWS-DQGDGGSPILGYVINYKREHGDWEELQVEAGTSE--HVLPNLWCGTRYQLYITAF 647
L W + DGG+PIL YV+ +RE G + V +G ++ + +L Y + A
Sbjct: 8001 LTWEPPEFDGGTPILHYVLE-RREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8059
Query: 648 NRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVI 703
N++G G ++ V A P P ++ +T+ W DGG I+ ++I
Sbjct: 8060 NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYII 8119
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
E + +W+ N ++ GL YQ R+ A N AG
Sbjct: 8120 EKIAKGEERWKR-CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 8164
Score = 128 bits (309), Expect = 1e-28
Identities = 164/708 (23%), Positives = 278/708 (39%), Gaps = 64/708 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P IR+ D +I + W++P Y G S + Y+V+ ++ E W + K V
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV--RT 20727
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ------SEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T V NL+P +Y+ R+ A N GQ +EP Q + E+ V AK
Sbjct: 20728 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 20787
Query: 182 SSTELIVT----WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
+ ++ V PP W + + L S++ I + + T+ V
Sbjct: 20788 AGEDVQVLIPFKGRPPPTVTWRKDE-------KNLGSDARYSIENTDSSSLLTIPQVTRN 20840
Query: 238 GTARSRTTL-SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
T + T+ +G+ + + V V+ D P+ LQ +S
Sbjct: 20841 DTGKYILTIENGVGEPKSSTVSVKVL------------------DTPAACQ-KLQVKHVS 20881
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+V + W+PP + G + I+ Y + T V+ + S L L T +
Sbjct: 20882 RGTVTLLWDPPLIDGGSPIIN-YVIEKRDATK--RTWSVVSHKCSSTSFKLIDLSEKTPF 20938
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V A G G +VP+ D+ S++ +++SW P G ++
Sbjct: 20939 FFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVI- 20997
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
T Y+ V G+ E T T E S+ ++ +F V A G + + +
Sbjct: 20998 -TEYV-VERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21055
Query: 477 LPSDSVPARITSFS----RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKN 531
+ + S + N+ L G P P+ +W +G+ L ES +
Sbjct: 21056 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 21115
Query: 532 VSSDGTLTISM--TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYAD 587
++ +T+S+ + G YT ++N R V TV PP P + + AD
Sbjct: 21116 SKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 21175
Query: 588 SLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S+ L W + +GG I Y I KRE +W+ + + +PNL YQ +
Sbjct: 21176 SVILSWDVPEDNGGGEITCYSIE-KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRV 21234
Query: 645 TAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYF 701
A NR G P I+ A + +P P + + + +++ W DGG + F
Sbjct: 21235 RAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGF 21294
Query: 702 VIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E +E + W+ V N+ + R + +GL YQ R+ A N+AG
Sbjct: 21295 HVEKKERNSILWQKV-NTSPISGREYRATGLVEGLDYQFRVYAENSAG 21341
Score = 127 bits (307), Expect = 2e-28
Identities = 179/723 (24%), Positives = 284/723 (39%), Gaps = 63/723 (8%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES- 113
+TV + I L P P IR+ + +I ISW P Y G I NYIV+ KE +
Sbjct: 18979 ITVPITIIVLDRPGPPGP--IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT 19036
Query: 114 WPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGP 172
W Q V + TS + L + Y R+ AENR G+S S+ V P GP
Sbjct: 19037 WHIVSQAV----ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGP 19092
Query: 173 PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
P +V + + ++VTW+ P D ++GY++ ++E S++L + A+ +
Sbjct: 19093 PGTPKVVHATKSTMLVTWQVPVND-GGSRVIGYHLEYKE---RSSILWSK----ANKIL- 19143
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
A ++ +SGL + Y V A N D P PPG +
Sbjct: 19144 ------IADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD-PCDPPGQPEV 19196
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
++ +SV + W P G + GY V + D + T I + ++ L
Sbjct: 19197 TNITRKSVSLKWSKPHYDG-GAKITGYIVERRELPDGRWLKCNYTN-IQETYFEVTELTE 19254
Query: 353 YTNYSVTVCAFTAAGD----GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
Y V A AA P+ + + P D+K R+ I+V
Sbjct: 19255 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKF----RDVIVVKAGEVL 19310
Query: 409 SPNGVLVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPP---RATHQFWVSASTR 464
N + G L +S +DG E R ST +H R T Q+ ++
Sbjct: 19311 KINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNV 19370
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G VL PA N +T E SLS + A
Sbjct: 19371 AGTRSVAVNCKVLDKPGPPAGPLEI--NGLTA--EKCSLSWGRPQEDGGADIDYYIVEKR 19426
Query: 525 ESTLRKNVSSDGTLTIS---MTQSADSGNYTCSVENI--HGRDEVTYTVEVK------VP 573
E++ +G L ++ +T+ Y V + +G E +V +K VP
Sbjct: 19427 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19486
Query: 574 PQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
P L + +S+ L WS + DGGS I GY+I + ++ W + + V
Sbjct: 19487 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19546
Query: 632 PN-LWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTVTV- 686
L G Y+ + A N G LP + ++ A +P P +++ TT+T+
Sbjct: 19547 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 19606
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W+ DGG I + +EY++ W+ S++ TE +++SGLT A Y R+ + N
Sbjct: 19607 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE--YTISGLTTGAEYVFRVKSVN 19664
Query: 747 NAG 749
G
Sbjct: 19665 KVG 19667
Score = 127 bits (306), Expect = 2e-28
Identities = 157/709 (22%), Positives = 287/709 (40%), Gaps = 69/709 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P ++V D T+ + W++P + G II YI++ +A W + V
Sbjct: 21757 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK--- 21813
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +LQ Y R+ A N G+ + + + + P D+ K T ++
Sbjct: 21814 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ-THVV 21872
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G + ++ +Q + + V S P ++ ++R + S T+
Sbjct: 21873 RA----------GASIRLFIAYQGRPTPTAVW--SKPD-SNLSLRADIHTTDSFSTLTVE 21919
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
++ A + N+ + D P PPG + ++ S + W+ P
Sbjct: 21920 NCNRNDAGKYTLTVENN---SGSKSITFTVKVLDTPG-PPGPITFKDVTRGSATLMWDAP 21975
Query: 308 PMRGRNGILQGYRVTYAPVT--DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
+ G + Y V + W + T+QI ++ G+ Y + V+
Sbjct: 21976 LLDG-GARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY--FRVSAVNEYG 22032
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVI 424
G+ TE+ P+ P + +S++ +++WL P G + GY L M
Sbjct: 22033 VGEPYEMPEPIVATEQ--PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM--- 22087
Query: 425 EDGREEGTHKRMLSPST--LSHETSRSPPRATHQFWVSASTRLGEGEA----TRVVTVLP 478
R++G+ + + T L+ R + ++F V A G E + V+ P
Sbjct: 22088 ---RQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP 22144
Query: 479 SDSVPARITSFSRNIVT-----PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
A +T + ++T P+ ++ +S G PAP TW + + L+ T R +++
Sbjct: 22145 QIEPTADLTGITNQLITCKAGSPFTIDVPIS----GRPAPKVTWKLEEMRLKETDRVSIT 22200
Query: 534 SDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADS 588
+ TLT+ + DSG Y ++EN G + TV V P P + V A+S
Sbjct: 22201 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAES 22260
Query: 589 LHLQWSDQGD-GGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
L W + D GG+ I Y++ KRE G W+ + ++ + +L Y ++
Sbjct: 22261 CVLSWGEPKDGGGTEITNYIVE-KRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVS 22319
Query: 646 AFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ NR G P + H + + P +P+ ++ N ++ W + + DGG I+
Sbjct: 22320 SENRFGVSKPLESAPIIAEHPFVPPSAPTRPE-VYHVSANAMSIR-WEEPYHDGGSKIIG 22377
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +E +E + W + N V E + V+GL YQ R A N AG
Sbjct: 22378 YWVEKKERNTILW-VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 22425
Score = 126 bits (305), Expect = 3e-28
Identities = 160/712 (22%), Positives = 284/712 (39%), Gaps = 63/712 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P PK ++ D ++ ++W P G SP+ Y+V+ +E T KV+ +
Sbjct: 6991 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRK---TWTKVMDFVTDL 7047
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+V +L Y ++ A N+ G EP+ +PV ++T VP PP++V+ +++
Sbjct: 7048 EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANS 7106
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP+ D I GY ++ P G+ V G A ++
Sbjct: 7107 IFLTWDPPKND-GGSRIKGY-------------IVERCPRGSDKWVAC--GEPVAETKME 7150
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL++ YA V+A N + D P L L+ +V+ +
Sbjct: 7151 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7210
Query: 306 ---PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVT-KQISGLHT-TLSGLRRYTNYSVTV 360
P + G+ ++T+ + +T + + T T+ +R + +
Sbjct: 7211 IELPATVTGK----PEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII 7266
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
A G RA V D P PA + L++W PP G + T Y
Sbjct: 7267 EAVNVCG---RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNY 7321
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLP 478
+ E HK + + + ++ P + F V+A G GE + +T
Sbjct: 7322 VVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKY 7381
Query: 479 SDSVPARITSFSRNIVTPWKENISLS-CNKVGVP-APATTWTMNGVGLEST----LRKNV 532
P T + +T K+ ++L+ C +P T + + + ++ K
Sbjct: 7382 QFDPPGPPTRLEPSDIT--KDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMP 7439
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVV-DSY 585
D T + + + EN+ G + + + E + PP PP V D
Sbjct: 7440 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVG 7499
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLY 643
S+ L W+ + DGG+ I YVI + D W + T++H+LP L G Y
Sbjct: 7500 KTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFR 7559
Query: 644 ITAFNRIG---TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
+ A N+ G P D V K P P+ ++I + T + W DGG I
Sbjct: 7560 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPIT 7619
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+++E R++ + W+ V +V+ T+ +V+ LT + Y R+ A N G +
Sbjct: 7620 NYIVEKRDVRRKGWQTVDTTVKDTK--CTVTPLTEGSLYVFRVAAENAIGQS 7669
Score = 126 bits (304), Expect = 4e-28
Identities = 125/486 (25%), Positives = 204/486 (41%), Gaps = 30/486 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTK 338
D P PP + +S S V+WEPP + G + I+ Y V A W VT
Sbjct: 13288 DTPG-PPVNVTVKEISKDSAYVTWEPPIIDGGSPIIN-YVVQKRDAERKSW----STVTT 13341
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ S ++ L +Y V A G G P D+K S++
Sbjct: 13342 ECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKS 13401
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
+ W P S G ++GY V++ EE +R++ +L + + F
Sbjct: 13402 SCSIGWKKPHSDGGSRIIGY-----VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456
Query: 458 WVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKENIS--LSCNKVGVPAPA 514
VSA GEG + + V D V P ++ KEN + L G PAP+
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13516
Query: 515 TTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
+W L + R +V S TL + Q +D+G YT +++N+ G E T +++V
Sbjct: 13517 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13576
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGT 626
P P + + A+++ L+W+ + DGGS I Y++ KR+ + W
Sbjct: 13577 GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSVNNKWVTCASAVQK 13635
Query: 627 SEHVLPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ + L G Y ++A N+ +G GL + + A VP P ++ + +V
Sbjct: 13636 TTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSV 13695
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W D GG I + +E++E + W+ +N R F V+GLT Y+ R+
Sbjct: 13696 SLTWTDPKKTGGSPITGYHLEFKERNSLLWKR-ANKTPIRMRDFKVTGLTEGLEYEFRVM 13754
Query: 744 AHNNAG 749
A N AG
Sbjct: 13755 AINLAG 13760
Score = 126 bits (303), Expect = 6e-28
Identities = 155/614 (25%), Positives = 250/614 (40%), Gaps = 50/614 (8%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S PV V + P P V+V +S + +TW PP +D G+ + +YV +
Sbjct: 17211 SFPVNVKVLDR-PGPPEGPVQVTGVTSEKCSLTWSPPLQD--GGSDISHYV----VEKRE 17263
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
T +A +TV E + T L ++ + V Y
Sbjct: 17264 TSRLA-------WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMK 17316
Query: 277 XXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNED 334
+P PP +L+ ++ S+ V W P G + I+ GY V + W
Sbjct: 17317 NPFV-LPG-PPKSLEVTNIAKDSMTVCWNRPDSDGGSEII-GYIVEKRDRSGIRWI---K 17370
Query: 335 AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA-APVYCHTEEDV--PSAPADIK 391
++I+ L ++GL Y V A AAG G + A VY + V P P +
Sbjct: 17371 CNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 17430
Query: 392 AAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST----LSHET 446
+++N I ++W P G ++GY V+E + + ++++P T E
Sbjct: 17431 IVDTTKNSITLAWGKPIYDGGSEILGY-----VVEICKADEEEWQIVTPQTGLRVTRFEI 17485
Query: 447 SRSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENI 501
S+ ++ V A ++G GEAT V TV P D + A + + IV +
Sbjct: 17486 SKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSA 17545
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHG 560
+ G P P TW+ ++ + T L+I D+G Y +EN G
Sbjct: 17546 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 17605
Query: 561 RDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGD 616
TV+V P PP LAV + DS L W DGG+ + YVI+ KRE
Sbjct: 17606 SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID-KRESTRKA 17664
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
+ + + + + NL G Y + A N G G+P + V A P P +
Sbjct: 17665 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17724
Query: 677 ITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
++ T+ + +W DGG +L +V+E + +W +V+ S + V V+GL+
Sbjct: 17725 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV--VTGLSSG 17781
Query: 736 AHYQLRITAHNNAG 749
YQ R+ A+N G
Sbjct: 17782 QEYQFRVKAYNEKG 17795
Score = 125 bits (301), Expect = 1e-27
Identities = 146/644 (22%), Positives = 248/644 (38%), Gaps = 41/644 (6%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+VTS S++ + N G + P+ + + GPP +R++ S
Sbjct: 18951 TVTSLSIKEASKEDVGTYELCVSNSAGSI--TVPITIIVLDR--PGPPGPIRIDEVSCDS 19006
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W PP+ D I Y V +E S + +++ AR+
Sbjct: 19007 ITISWNPPEYD-GGCQISNYIVEKKETTSTTWHIVSQA---------------VARTSIK 19050
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSW 304
+ L + Y V A N P PPG + + ++ V+W
Sbjct: 19051 IVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 19110
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
+ P G + ++ GY + Y + ++ A I+ +SGL Y V A
Sbjct: 19111 QVPVNDGGSRVI-GYHLEYKERSSILWSK-ANKILIADTQMKVSGLDEGLMYEYRVYAEN 19168
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSV 423
AG G + D P + +R + + W P G + GY +
Sbjct: 19169 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19228
Query: 424 IEDGREEGTHKRMLSPSTLS-HETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+ DGR + + + E + F +A+ + E + ++ D
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288
Query: 483 PARI---TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDG-- 536
P R+ F IV E + ++ + G P P +W +G+ +E R +S+D
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
LT+ D+G Y +++N+ G V +V P PP L + A+ L W
Sbjct: 19349 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWG 19408
Query: 595 -DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
Q DGG+ I Y++ KRE H W + E + + L G Y +T N+ G
Sbjct: 19409 RPQEDGGADIDYYIVE-KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYG 19467
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
G P + + A TVP P ++ ++ ++T+ W DGG I ++IE RE
Sbjct: 19468 VGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREK 19527
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+ +W V+ RV S +GL Y+ R+ A N AG +L
Sbjct: 19528 NSLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSL 19570
Score = 124 bits (299), Expect = 2e-27
Identities = 157/633 (24%), Positives = 243/633 (38%), Gaps = 56/633 (8%)
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
H + N G++ + V V P+GP V+++ ++ + ++W PP+ D G+
Sbjct: 15720 HYVVKLTNSAGEAIETLNVIVLDKPGPPTGP---VKMDEVTADSITLSWGPPKYD--GGS 15774
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ Y+ + S +T I S A AR+ L+ Y + A
Sbjct: 15775 SINNYIVEKRDTSTTTWQIVS--------------ATVARTTIKACRLKTGCEYQFRIAA 15820
Query: 262 YN--SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
N + VP PPG S S+ V W P G + ++ GY
Sbjct: 15821 ENRYGKSTYLNSEPTVAQYPFKVPG-PPGTPVVTLSSRDSMEVQWNEPISDGGSRVI-GY 15878
Query: 320 RVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
+ W Q TT GL Y V A G G + C
Sbjct: 15879 HLERKERNSILWVKLNKTPIPQTK-FKTT--GLEEGVEYEFRVSAENIVGIGKPSKVSEC 15935
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRM 436
+ D P +A + +RN + + W P+ G + GY + + +GR K
Sbjct: 15936 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGR---WMKAS 15992
Query: 437 LSPSTLSH-ETSRSPPRATHQFWVSASTRLG----EGEATRVVTVLPSDSV-PARIT--- 487
+ +H E + ++F V A G E+T +T D V P RI+
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITA--RDEVDPPRISMDP 16050
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA 546
+ IV E+ + + G P P W L +T R + S+D ++S+ +
Sbjct: 16051 KYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAV 16110
Query: 547 --DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQ-GDGGS 601
DSGNY +N+ G VT V+V P PP VV S A+ L W DGGS
Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 16170
Query: 602 PILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
I+ Y++ +RE W + T + L G Y I A N+ G G P +
Sbjct: 16171 DIINYIVE-RRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE 16229
Query: 660 HAYTKG--TVPVKPKHSQMITL-NTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
K VP PK ++ T+ + + VW DGG IL +V+E R+ +W
Sbjct: 16230 PVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC 16289
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ R+ V+GL Y+ R++A N AG
Sbjct: 16290 HKRLIGELRL-RVTGLIENHDYEFRVSAENAAG 16321
Score = 121 bits (291), Expect = 2e-26
Identities = 121/483 (25%), Positives = 198/483 (40%), Gaps = 28/483 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
PG + + ++ S+ ++W P G + I Q Y + + + IS
Sbjct: 21658 PGIPEPSNITGNSITLTWARPESDGGSEIQQ-YILERREKKSTRWVKVISKRPISETRFK 21716
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAAVSSRNKILVS 403
++GL Y V A AAG G + + C + P P +K +S+ + +
Sbjct: 21717 VTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLE 21776
Query: 404 WLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSA 461
W P G+ ++GY + M + G HK + T ++F VSA
Sbjct: 21777 WSKPVFDGGMEIIGYIIEMCKADLG---DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 21833
Query: 462 STRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G+G++ V T+ D + A +F + V +I L G P P
Sbjct: 21834 INGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAV 21893
Query: 517 WTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W+ L +LR ++ S TLT+ D+G YT +VEN G +T+TV+V
Sbjct: 21894 WSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDT 21951
Query: 574 PQPP-ILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEH 629
P PP + D S L W + DGG+ I YV+ KRE W+ + +
Sbjct: 21952 PGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE-KREASRRSWQVISEKCTRQIF 22010
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWL 688
+ +L G Y ++A N G G P ++ P P+ ++ T ++ V WL
Sbjct: 22011 KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWL 22070
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG I +++E R+ W ++ Q T F+V L Y+ R+ A N+A
Sbjct: 22071 KPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLT---FTVERLVEKTEYEFRVKAKNDA 22127
Query: 749 GHA 751
G++
Sbjct: 22128 GYS 22130
Score = 120 bits (288), Expect = 4e-26
Identities = 126/485 (25%), Positives = 194/485 (40%), Gaps = 31/485 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG + ++ S+ V W P G + I GY + G + + I
Sbjct: 20571 PPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKS-LGWFKVLKETIRDTRQ 20628
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILV 402
++GL ++Y VCA AAG G + P + D P PA I+ A S+++ I +
Sbjct: 20629 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20688
Query: 403 SWLPPSSPNGVLVGYTLYMSVIEDGREE--GTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P G V T Y+ I G EE T T + S P + F VS
Sbjct: 20689 GWSKPVYDGGSAV--TGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 20746
Query: 461 ASTRLGEG------EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G+G E + +L + + + + +++ E++ + G P P
Sbjct: 20747 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDV-ALRTSVIAKAGEDVQVLIPFKGRPPPT 20805
Query: 515 TTWTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + L S R +N S LTI D+G Y ++EN G + + TV VK
Sbjct: 20806 VTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVK 20864
Query: 572 VPPQPPI---LAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P L V ++ L W DGGSPI+ YVI KR+ W + +
Sbjct: 20865 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE-KRDATKRTWSVVSHKCS 20923
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH-SQMITLNTTTV 684
++ L +L T + + A N IG G PC+ VP + S + T+ +
Sbjct: 20924 STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI 20983
Query: 685 TVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
W DGG I +V+E + + W S++ + VS L + + R+ A
Sbjct: 20984 LSWTKPDFDGGSVITEYVVERKGKGEQTW---SHAGISKTCEIEVSQLKEQSVLEFRVFA 21040
Query: 745 HNNAG 749
N G
Sbjct: 21041 KNEKG 21045
Score = 119 bits (286), Expect = 7e-26
Identities = 151/616 (24%), Positives = 230/616 (37%), Gaps = 48/616 (7%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S+ ++V ++ P P ++++ +T + ++WEPP+ D + GY V ++
Sbjct: 23324 SETIKVIILDK-PGPPTGPIKIDEIDATSITISWEPPELD-GGAPLSGYVVEQRD----- 23376
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
A PG + RS + L + Y V A N
Sbjct: 23377 ----AHRPGWLPVS------ESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVI 23426
Query: 277 XXMEDV--PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNE 333
+ P PP LQ +S + ++W PP G + + GY V V D +
Sbjct: 23427 ECRSSIRIPG-PPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRADRWVRV 23484
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADI 390
+ V ++ +T GL Y V A A G G + P D P P +
Sbjct: 23485 NKVPVTMTRYRST--GLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 23542
Query: 391 KAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
+ ++R + ++W P G V GY + M ++ + E T + +
Sbjct: 23543 RVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD--QHEWTKCNTTPTKIREYTLTHL 23600
Query: 450 PPRATHQFWVSASTRLGEGEATRV---VTVLPSDSVPARITS--FSRNIVTPWKENISLS 504
P A ++F V A G GE V V V P + I I L+
Sbjct: 23601 PQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLT 23660
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDE 563
G P P WT G + S T L I DSG Y +EN G+
Sbjct: 23661 IPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKA 23720
Query: 564 VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR-EHGDWEE 619
V V V P P L D S+ + W D GG+ ILGY++ + W
Sbjct: 23721 VYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT 23780
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMI 677
+ + V+ L Y ++A N+ G P T T P +P +
Sbjct: 23781 IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 23840
Query: 678 TLNTTTVTVWLDSWG----DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
L+ T +V L SW DGG + + IE +E S +W + N Q T +++V+GL
Sbjct: 23841 VLDVTKSSVSL-SWSRPKDDGGSRVTGYYIERKETSTDKW-VRHNKTQITTTMYTVTGLV 23898
Query: 734 PAAHYQLRITAHNNAG 749
P A YQ RI A N+ G
Sbjct: 23899 PDAEYQFRIIAQNDVG 23914
Score = 118 bits (285), Expect = 9e-26
Identities = 164/709 (23%), Positives = 270/709 (38%), Gaps = 57/709 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N +VID ++ +SW++P Y G I YIV+ + W TP I +
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI---N 16397
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T+ V+ L Y+ RI A N+ G E + EE P D+ +E + +
Sbjct: 16398 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINI 16457
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
G L +V + T + G + ++ + L
Sbjct: 16458 RA-----------GGSLRLFV---PIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 16503
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ ++ + + NS + D PS PP L+ ++ SV ++WEP
Sbjct: 16504 DNVNRYDSGKYTLTLENS---SGTKSAFVTVRVLDTPS-PPVNLKVTEITKDSVSITWEP 16559
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + G + I + Y V T + AV + L+ +Y V A
Sbjct: 16560 PLLDGGSKI-KNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16616
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIE 425
G G+ A +VP P I +RN + +SW P G ++ Y + M
Sbjct: 16617 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16676
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE----ATRVVT---VLP 478
+ + + +++ T + F V A G + A +V V+
Sbjct: 16677 SEKWSECARVKSLQAVITNLTQGEE----YLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE 16732
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD--- 535
D PA +S+S + K + +S G P P TWT +G+ L+ T R NV+
Sbjct: 16733 PDVKPA-FSSYSVQVGQDLKIEVPIS----GRPKPTITWTKDGLPLKQTTRINVTDSLDL 16787
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADSLHLQW 593
TL+I T D G Y +V N+ G+ + + P PP V D A+S+ L W
Sbjct: 16788 TTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSW 16847
Query: 594 SDQ-GDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ GG I Y++ KR+ W+ + + + L GT YQ I A NR
Sbjct: 16848 NPPLYTGGCQITNYIVQ-KRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRY 16906
Query: 651 GT--GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYRE 707
G L D + A P P ++ ++ + W + +GG ++ + +E +E
Sbjct: 16907 GQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKE 16966
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYN 756
+ W V+ ++ + F L Y+ R+ A N G A N
Sbjct: 16967 RNSILWTKVNKTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17014
Score = 118 bits (283), Expect = 2e-25
Identities = 156/650 (24%), Positives = 247/650 (38%), Gaps = 60/650 (9%)
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+T+ S++ I N +GQ S +++ T ++ P P V+ + S+ +
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTAS--IEIVTLDK-PDPPKGPVKFDDVSAESI 16843
Query: 187 IVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++W PP L+ G I Y V Q+ ++ +TV V A AR+
Sbjct: 16844 TLSWNPP---LYTGGCQITNYIV--QKRDTTTTVW-------------DVVSATVARTTL 16885
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL-PPGALQCNALSSQSVRVS 303
++ L+ Y + A N PPG A+S S+ +
Sbjct: 16886 KVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQ 16945
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G + ++ GY + + V K I +H T L Y V
Sbjct: 16946 WHEPVNNGGSPVI-GYHLERKERNSILWTK--VNKTI--IHDTQFKAQNLEEGIEYEFRV 17000
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTL 419
A G G + C+ D P + + RN+I + W P G ++ GY +
Sbjct: 17001 YAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIV 17060
Query: 420 YMSVIEDGR-EEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLG----EGEATRV 473
+ DGR + + ++ T+S T ++F V A G ++T
Sbjct: 17061 EKRDLPDGRWMKASFTNVIETQFTVSGLTEDQ----RYEFRVIAKNAAGAISKPSDSTGP 17116
Query: 474 VTVLPSDSVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR- 529
+T +P RI+ F IV E L + G P P W +E + R
Sbjct: 17117 ITAKDEVELP-RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 17175
Query: 530 --KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSY 585
KN L + D G Y N+ G V+V P PP + V
Sbjct: 17176 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVT 17235
Query: 586 ADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQL 642
++ L WS DGGS I YV+ KRE W + E T+ + L G Y
Sbjct: 17236 SEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVF 17294
Query: 643 YITAFNRIGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
I A N+ G G P + K +P PK ++ + ++TV W DGG I+
Sbjct: 17295 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEII 17354
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++E R+ S +W + N + T+ V+GLT Y+ R++A N AG
Sbjct: 17355 GYIVEKRDRSGIRW-IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAG 17403
Score = 118 bits (283), Expect = 2e-25
Identities = 160/702 (22%), Positives = 267/702 (38%), Gaps = 57/702 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N ++D +I ++W +P Y G S I+ Y+V+ +A E W TPQ +
Sbjct: 17423 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL---R 17479
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
VT + L Y +R+ A N++G E + E+ P D+ E + +
Sbjct: 17480 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG--I 17537
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+V G ++ F+ T I +T + G ++ ++
Sbjct: 17538 VVR---------AGGSARIHIPFK---GRPTPEITWSREEGEFTDKVQIEKGVNYTQLSI 17585
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ A +++ NS + D P PP L + S + WEP
Sbjct: 17586 DNCDRNDAGKYILKLENS---SGSKSAFVTVKVLDTPG-PPQNLAVKEVRKDSAFLVWEP 17641
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P + G ++ Y + T Y N V+ + S + L Y V A
Sbjct: 17642 PIIDG-GAKVKNYVIDKRESTRKAYAN---VSSKCSKTSFKVENLTEGAIYYFRVMAENE 17697
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVI 424
G GV V + PS P + S+ + W P G V GY + M
Sbjct: 17698 FGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM--- 17754
Query: 425 EDGREEGTHK-RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRV-VTVLPSDS 481
+ +GT K +++ S + + +QF V A G+ + + V V+ D
Sbjct: 17755 ---QPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17811
Query: 482 V--PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P+ F+ + E++ + +G P P +W +G L+ T R NV T T
Sbjct: 17812 TIQPSLKLPFNTYSIQAG-EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870
Query: 540 ISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
+ + D G YT + N G +V V P PP+ + + AD + + W
Sbjct: 17871 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWE 17930
Query: 595 DQG-DGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
GG I Y++ KR+ W + + + L GT YQ I A NR G
Sbjct: 17931 PPAYTGGCQISNYIVE-KRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYG 17989
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
P D V P P + +++ + V W + DGG I+ + +E +E
Sbjct: 17990 KSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEK 18049
Query: 709 SQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ W +L +Q T+ F +GL Y+ +++A N G
Sbjct: 18050 NSILWVKLNKTPIQDTK--FKTTGLDEGLEYEFKVSAENIVG 18089
Score = 117 bits (282), Expect = 2e-25
Identities = 150/625 (24%), Positives = 245/625 (39%), Gaps = 46/625 (7%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
+ A N +G+ +QV ++P P ++ + SS + +W+PP+ D I
Sbjct: 14641 LTARNIVGEVGDVITIQV---HDIPGPPTGPIKFDEVSSDFVTFSWDPPEND-GGVPISN 14696
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y V ++ +S + V +A+ +RT T ++ +GL+ + V Q
Sbjct: 14697 YVVEMRQTDSTTWVELATT------VIRT-----TYKATRLTTGLEYQ--FRVKAQNRYG 14743
Query: 265 RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA 324
VP PPG Q A++ S+ +SW P G + IL GY V
Sbjct: 14744 VGPGITSACIVANYPFKVPG-PPGTPQVTAVTKDSMTISWHEPLSDGGSPIL-GYHVERK 14801
Query: 325 PVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
W A+ + G SGL Y V A AG + P D
Sbjct: 14802 ERNGILWQTVSKAL---VPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALD 14858
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST 441
P +R+ + + W P G + Y + + +GR + + +
Sbjct: 14859 PIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE 14918
Query: 442 LSHETSRSPPRATHQFWVSASTRLGE----GEATRVVTVLPSDSVPA-RI-TSFSRNIVT 495
+ S A ++F V A G E + +T P ++ F ++
Sbjct: 14919 FT--VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGTLTISMTQSA--DSGNYT 552
E L + G P P W+ +G LE T + + +D + + S DSG YT
Sbjct: 14977 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 553 CSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYADSLHLQW-SDQGDGGSPILGYVIN 609
+ N G + + V+V P PP LAV + ++ L W DGG+ I Y++
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15096
Query: 610 YKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKG 665
KRE W + E ++ + L G Y + A N+ G G P + V A
Sbjct: 15097 -KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY 15155
Query: 666 TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
P PK+ ++ T+ ++ V W DGG I+ +++E R+ + +W + N T+
Sbjct: 15156 GPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRW-IKCNKKTLTD 15214
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ VSGLT Y+ RI A N AG
Sbjct: 15215 LRYKVSGLTEGHEYEFRIMAENAAG 15239
Score = 117 bits (281), Expect = 3e-25
Identities = 141/615 (22%), Positives = 239/615 (38%), Gaps = 52/615 (8%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ V T PS P +R + + +I++W+ P+ D G I Y + +E + +
Sbjct: 21151 PITVITLGP-PSKPKGPIRFDEIKADSVILSWDVPE-DNGGGEITCYSIEKRETSQTNWK 21208
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
++ S AR+ + L K A Y V+A N
Sbjct: 21209 MVCSS---------------VARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVA 21253
Query: 279 MED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV 336
+P PPG ++S + ++W+ P G + + G+ V +
Sbjct: 21254 KHQFRIPG-PPGKPVIYNVTSDGMSLTWDAPVYDGGSEVT-GFHVEKKERNSILWQK-VN 21310
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAA 393
T ISG +GL +Y V A +AG + P + D P P I
Sbjct: 21311 TSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDV- 21369
Query: 394 VSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR 452
+R I + W PP G +VGY++ G E S + + P
Sbjct: 21370 --TRETITLKWNPPLRDGGSKIVGYSIEK---RQGNERWVRCNFTDVSECQYTVTGLSPG 21424
Query: 453 ATHQFWVSASTRLGE---GEATRVVTVLPSDSVPARIT---SFSRNIVTPWKENISLSCN 506
++F + A +G + + + ++VP + + ++ E++ +
Sbjct: 21425 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21484
Query: 507 KVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTISMTQSADS--GNYTCSVENIHGRDE 563
G P P TW +GV +E + ++ G+ ++ + + G YT +N G +
Sbjct: 21485 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21544
Query: 564 VTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHGD--WE 618
V+V+ P + + + + + L W + DG +PI Y+I KRE W
Sbjct: 21545 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE-KRETSRLAWA 21603
Query: 619 ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKGTVPVKP--KHS 674
++ + + L G YQ ++A N+ G G P D V A + TVP P
Sbjct: 21604 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21663
Query: 675 QMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
IT N+ T+T W DGG I +++E RE +W V + +E F V+GLT
Sbjct: 21664 SNITGNSITLT-WARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTE 21722
Query: 735 AAHYQLRITAHNNAG 749
Y+ + A N AG
Sbjct: 21723 GNEYEFHVMAENAAG 21737
Score = 114 bits (275), Expect = 1e-24
Identities = 118/490 (24%), Positives = 191/490 (38%), Gaps = 33/490 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQ 339
VPS P A + ++ + V+W+ P G + I+ GY + W D + +
Sbjct: 12594 VPSEPKNA-RVTKVNKDCIFVAWDRPDSDGGSPII-GYLIERKERNSLLWVKANDTLVRS 12651
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
+GL YS + A AG + P T P + +++
Sbjct: 12652 TE---YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST 12708
Query: 400 ILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+ + W P G ++GY + + + + + + +A +QF
Sbjct: 12709 VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFR 12768
Query: 459 VSASTRLG---EGEATRVVTVLPSDSVPARI---TSFSRNIVTPWKENISLSCNKVGVPA 512
A T + E + VT+L +++VP RI + + N+ L G P
Sbjct: 12769 AIARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 12827
Query: 513 PATTWTMNGV------GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
P +W +G G++ +++N+ TL + DSG+YT + EN G T
Sbjct: 12828 PTVSWKKDGTLLKPAEGIKMAMQRNLC---TLELFSVNRKDSGDYTITAENSSGSKSATI 12884
Query: 567 TVEVKVPPQPPILAVVDS-YADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQV 622
++V P PP ++ Y+D L W DGGS I Y+++ KRE +W ++
Sbjct: 12885 KLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD-KRETSRPNWAQVSA 12943
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L G YQ I A N+ G G P A K + + N T
Sbjct: 12944 TVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNIT 13003
Query: 683 T--VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+TV W DGG I +++E RE W V N ER +GL Y+
Sbjct: 13004 KDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKV-NRKPIIERTLKATGLQEGTEYE 13062
Query: 740 LRITAHNNAG 749
R+TA N AG
Sbjct: 13063 FRVTAINKAG 13072
Score = 113 bits (273), Expect = 2e-24
Identities = 122/493 (24%), Positives = 197/493 (39%), Gaps = 35/493 (7%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYG-NEDAVTKQISGL 343
P + +S + + V W PP G I GY + T W N+ A+ ++ +
Sbjct: 11902 PDPPEVTKVSKEEMTVVWNPPEYDGGKSIT-GYFLEKKEKHSTRWVPVNKSAIPERRMKV 11960
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
L Y V A G G + + PV + P P + + ++++ I
Sbjct: 11961 QNLLPD----HEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 12016
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHE---TSRSPPRATH 455
+ W P G ++GY + M I D + KR + + L + + +
Sbjct: 12017 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 12076
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSV--PARI---TSFSRNIVTPWKENISLSCNKVGV 510
+F V A ++G G + + + P I S + ++ I L G
Sbjct: 12077 EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR 12136
Query: 511 PAPATTWTMNGVGLESTLRKN----VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
PAP TW VG+++ +RK V + L I + DSG Y+ ++ N G V
Sbjct: 12137 PAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12194
Query: 567 TVEVKVPPQPPI-LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKR-EHGDWEELQVE 623
V V P P L V D S H+ W+ + DGGS + Y++ + + W + E
Sbjct: 12195 NVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE 12254
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
+ + NL G Y +TA N G G+P D+ V A + P P+ ++ +
Sbjct: 12255 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12314
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+ T+ WL DGG I ++ YRE QP R SV + V+GL Y+
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYK 12373
Query: 740 LRITAHNNAGHAL 752
R+ A N G +L
Sbjct: 12374 FRVAARNAVGVSL 12386
Score = 113 bits (271), Expect = 4e-24
Identities = 150/629 (23%), Positives = 244/629 (38%), Gaps = 58/629 (9%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I AEN G + ++V + P GPP V++ S +++WEPP D I
Sbjct: 12871 ITAENSSGSKSATIKLKVL---DKP-GPPASVKINKMYSDRAMLSWEPPLED-GGSEITN 12925
Query: 205 YYVGFQELNS-NSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y V +E + N + A+ P + + +EG H Y + A N
Sbjct: 12926 YIVDKRETSRPNWAQVSATVPITSCSVEKLIEG---------------HE-YQFRICAEN 12969
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSS---QSVRVSWEPPPMRGRNGILQGYR 320
P PPG +S+ + VSW+PP G + I GY
Sbjct: 12970 KYGVGDPVFTEPAIAKN--PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPIT-GYL 13026
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYC 377
+ T K I +GL+ T Y V A AG G + Y
Sbjct: 13027 LEKRE-TQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYA 13085
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTH-KR 435
+ P+ PA K ++R+ + +SW P+ G ++GY ++E R + + R
Sbjct: 13086 RDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGY-----LVEVKRADSDNWVR 13140
Query: 436 MLSPSTLSH---ETSRSPPRATHQFWVSASTRLGEGEATRVVTV-LPSDS-VPAR---IT 487
P L E + +QF V A ++G + + V P D +P
Sbjct: 13141 CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDA 13200
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS---DGTLTISMTQ 544
+ ++ + L G P P TW+ V L + ++ S D L
Sbjct: 13201 DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVN 13260
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQ-GDGGSP 602
D+G Y ++EN G+ E T V+V P PP+ + V + DS ++ W DGGSP
Sbjct: 13261 KYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSP 13320
Query: 603 ILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
I+ YV+ + E W + E + + NL G Y + A N G G P + A
Sbjct: 13321 IINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 13380
Query: 662 YTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSV 720
P ++ +++ ++ ++ W DGG I+ +V+++ + +W+ V S+
Sbjct: 13381 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL 13439
Query: 721 QATERVFSVSGLTPAAHYQLRITAHNNAG 749
+S LT Y R++A N G
Sbjct: 13440 SLQ---YSAKDLTEGKEYTFRVSAENENG 13465
Score = 111 bits (268), Expect = 1e-23
Identities = 114/482 (23%), Positives = 185/482 (38%), Gaps = 20/482 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P L+ ++ SV + W+ P + G + I Y V T + T +
Sbjct: 14369 DTPG-PVLNLRPTDITKDSVTLHWDLPLIDGGSRITN-YIVEKREATR--KSYSTATTKC 14424
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
++GL Y V A G G + PS P + +++ +
Sbjct: 14425 HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTV 14484
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
++W P G + GY + G ++ TH + T Q
Sbjct: 14485 SLAWPKPKHDGGSKITGYVIEAQ--RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMA 14542
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTW 517
S +R V V +P + + ++ +NI + +G P P TW
Sbjct: 14543 VNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW 14602
Query: 518 TMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L+ T R N + T L I+ +DSG Y + NI G T++V P
Sbjct: 14603 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 14662
Query: 575 QPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
PP + + +D + W + DGG PI YV+ ++ + W EL + +
Sbjct: 14663 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14722
Query: 631 LPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-W 687
L G YQ + A NR +G G+ + A VP P Q+ + ++T+ W
Sbjct: 14723 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14782
Query: 688 LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNN 747
+ DGG IL + +E +E + W+ VS ++ +F SGLT Y+ R+ A N
Sbjct: 14783 HEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGIAYEFRVIAENM 14841
Query: 748 AG 749
AG
Sbjct: 14842 AG 14843
Score = 111 bits (266), Expect = 2e-23
Identities = 155/701 (22%), Positives = 253/701 (36%), Gaps = 48/701 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ-YKEAPESWPSTPQKVIVPGSV 127
P P N ++ D+ T + WT+P + G SPI+ Y+V+ K W + ++
Sbjct: 11307 PGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELI--RQ 11364
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L Y RI A N +G+ EP + + +++ PP+ VE + +
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH-PPE---VELDVTCRDV 11420
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+T Q + G VL+ V ++ + +
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK------RVDLIQDLPRVELQIKEA 11474
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
H Y ++ A NS + D P P L+ ++ ++ +SWE P
Sbjct: 11475 VRADHGKY--IISAKNS---SGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENP 11528
Query: 308 PMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
G + I + V Y W VTK++ + L Y VCA
Sbjct: 11529 LDNGGSEITN-FIVEYRKPNQKGWSIVASDVTKRL-----IKANLLANNEYYFRVCAENK 11582
Query: 366 AGDGVRA---APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL-VGYTLYM 421
G G P+ D P P ++ A + + + W P G + Y +
Sbjct: 11583 VGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVER 11642
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
+ E HK + + + R ++F V GE + + V+ +
Sbjct: 11643 RLKGSDDWERVHKGSIKET--HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKED 11700
Query: 482 VPARITSFSRNIVTPWK--ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---- 535
+ + + V K + I L G P P WT + + T V D
Sbjct: 11701 LQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760
Query: 536 -GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQW 593
+++ + +D G Y + N G TV V P P L +VD +D + W
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCW 11820
Query: 594 SD-QGDGGSPILGYVINY-KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ DGG I Y++ + + W T + L G Y + A N+IG
Sbjct: 11821 DPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG 11880
Query: 652 TGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREM 708
TG P + V A TK P +P ++ ++ +T VW DGG I + +E +E
Sbjct: 11881 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEK 11940
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ S ER V L P YQ R+ A N G
Sbjct: 11941 HSTRWVPVNKSA-IPERRMKVQNLLPDHEYQFRVKAENEIG 11980
Score = 110 bits (265), Expect = 2e-23
Identities = 119/481 (24%), Positives = 182/481 (37%), Gaps = 21/481 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D PS P L + SV +SWEPP + G + Y V T +T
Sbjct: 18700 DSPSAPVN-LTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTR--KAYATITNNC 18755
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
+ + L+ +Y V A G G+ A + P P + +RN
Sbjct: 18756 TKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTA 18815
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
+ W P S G + GY + M G E+ + + TL S + F V
Sbjct: 18816 TIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVK--TLEATISGLTAGEEYVFRV 18871
Query: 460 SASTRLGEGEATRV-VTVLPSD-SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+A G + ++ V V+ D + + +E + + G P W
Sbjct: 18872 AAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNW 18931
Query: 518 TMNGVGLESTLRKNVSSDGTLT---ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+G L+ T R NVSS T+T I D G Y V N G V T+ V P
Sbjct: 18932 RKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRP 18991
Query: 575 QPPILAVVDSYA-DSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
PP +D + DS+ + W+ + DGG I Y++ K W + + +
Sbjct: 18992 GPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKI 19051
Query: 632 PNLWCGTRYQLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WL 688
L G+ YQ + A NR G V A + P P +++ +T+ V W
Sbjct: 19052 VRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQ 19111
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG ++ + +EY+E S W +N + + VSGL Y+ R+ A N A
Sbjct: 19112 VPVNDGGSRVIGYHLEYKERSSILWS-KANKILIADTQMKVSGLDEGLMYEYRVYAENIA 19170
Query: 749 G 749
G
Sbjct: 19171 G 19171
Score = 109 bits (263), Expect = 4e-23
Identities = 124/473 (26%), Positives = 189/473 (39%), Gaps = 24/473 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI-SGLHTTLSGLRRY 353
++S S+ V W P G + IL GY + V + + V K + + L + GL
Sbjct: 8417 VTSNSMLVKWNEPKDNG-SPIL-GYWLEKREVNSTHWSR--VNKSLLNALKANVDGLLEG 8472
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSWLPPS-SP 410
Y VCA AAG G + P T D P P + +S I + W PP+ +
Sbjct: 8473 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNG 8532
Query: 411 NGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE- 469
G +VGY + ++ ++M+ + + R A ++ VSA GEG
Sbjct: 8533 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE--GADYKLRVSAVNAAGEGPP 8590
Query: 470 -ATRVVTVLPSDSVPA--RITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
T+ VTV PA S I + + + G P P WT L+
Sbjct: 8591 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK 8650
Query: 527 --TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVD 583
+ NV + L I D G Y + N G VEV P P + L V
Sbjct: 8651 DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVV 8710
Query: 584 SYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
+ L WSD + DGGS I G++I K + W + +E S+ + L G Y+
Sbjct: 8711 TNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-PIETERSKCDITGLLEGQEYK 8769
Query: 642 LYITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
+ A N+ G G P +I + A P P+ +T+T+ W + +GG I
Sbjct: 8770 FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPI 8829
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
++IE R +P + V+ + T F V L Y+ R+ A N G +
Sbjct: 8830 QGYIIEKRRHDKPDFERVNKRLCPTTS-FLVENLDEHQMYEFRVKAVNEIGES 8881
Score = 109 bits (263), Expect = 4e-23
Identities = 120/487 (24%), Positives = 189/487 (38%), Gaps = 28/487 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + +A++ S+ V+W P G I +GY + + K ++
Sbjct: 18404 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEI-EGY-ILEKRDKEGVRWTKCNKKTLTD 18461
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNK 399
L ++GL +Y V A AAG G + P + D P P++ K +SR+
Sbjct: 18462 LRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSS 18521
Query: 400 ILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHE---TSRSPPRATH 455
+ ++W P G V GY + V E +E T P+ L + ++ +
Sbjct: 18522 VSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWT--TCTPPTGLQGKQFTVTKLKENTEY 18577
Query: 456 QFWVSASTRLGEGE-ATRVVTVLPSDSV-PARI---TSFSRNIVTPWKENISLSCNKVGV 510
F + A G GE AT +V+ + + P I + +V + L G
Sbjct: 18578 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 18637
Query: 511 PAPATTWTM-NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P P W G+ + + SS L I DSG Y ++EN G V
Sbjct: 18638 PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVR 18697
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P P+ L + + DS+ L W DGG+ I Y++ KRE + +
Sbjct: 18698 VLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYATITNNCT 18756
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ + NL G Y + A N G GLP + P+ P ++ + T T
Sbjct: 18757 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTAT 18816
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG I +V+E + +W S Q ++SGLT Y R+ A
Sbjct: 18817 IKWEKPESDGGSKITGYVVEMQTKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAA 18873
Query: 745 HNNAGHA 751
N G +
Sbjct: 18874 VNEKGRS 18880
Score = 109 bits (261), Expect = 7e-23
Identities = 124/489 (25%), Positives = 186/489 (38%), Gaps = 37/489 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISG 342
PPG ++S + V W P G I+ GY + W N+ + Q +
Sbjct: 18010 PPGTPFVTSISKDQMLVQWHEPVNDGGTKII-GYHLEQKEKNSILWVKLNKTPI--QDTK 18066
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT GL Y V A G G + C D P +A V +RN + +
Sbjct: 18067 FKTT--GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTL 18124
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGR-EEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P+ G + GY + + DGR + + +L S ++F V
Sbjct: 18125 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE---FTVSGLVEDQRYEFRVI 18181
Query: 461 ASTRLGE----GEATRVVTVLPSDSVP--ARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G +++ +T P + + IV E L + G P P
Sbjct: 18182 ARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPD 18241
Query: 515 TTWTMNGVGLESTLR----KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
W+ +G LE T K+ TL + D G Y + N+ G + TV+V
Sbjct: 18242 VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Query: 571 KVPPQPP--ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAG 625
P PP L V A+ +L W+ DGG+ I Y+I KRE W ++ E
Sbjct: 18302 LDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE-KRETSRLSWTQVSTEVQ 18360
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD-----IVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A N+ G G P + + Y P P+ S IT +
Sbjct: 18361 ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS-AITKD 18419
Query: 681 TTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQL 740
+ VT W DGG I +++E R+ +W N T+ V+GLT Y+
Sbjct: 18420 SMVVT-WARPVDDGGTEIEGYILEKRDKEGVRW-TKCNKKTLTDLRLRVTGLTEGHSYEF 18477
Query: 741 RITAHNNAG 749
R+ A N AG
Sbjct: 18478 RVAAENAAG 18486
Score = 108 bits (260), Expect = 9e-23
Identities = 158/700 (22%), Positives = 270/700 (38%), Gaps = 47/700 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYK-EAPESWPSTPQKVIVPGSV 127
P P +V D + + W+ P G S + YIV+YK E E W K +
Sbjct: 9924 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV---RG 9980
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T V L+ Y R+ A N G EP + V ++ P D++++A ++
Sbjct: 9981 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSP--DLQLDASVRDRIV 10038
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V R I+ Y G + + P A T+E + S +
Sbjct: 10039 VHAGGVIR------IIAYVSGKPPPTVTWNMNERTLPQEA-----TIETTAISSSMVIKN 10087
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ H V + ++ + DVP + L+++S +++W P
Sbjct: 10088 CQRSHQG----VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I V +D VT ++ + T+ GL + Y + A + G
Sbjct: 10144 EDDGGSPITN--YVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIG 10200
Query: 368 DG--VRAAPVYCHTEE-DVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSV 423
G V + E VP P D++ ++N + ++W PP G ++ Y L +
Sbjct: 10201 MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRL 10260
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRA--THQFWVSASTRLGEGE---ATRVVTVLP 478
I G E+ HK + + + LS + + + T+++ VSA +G+G+ T+ +T
Sbjct: 10261 I--GTEK-FHK-VTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD 10316
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGT 537
+ P F + E +L+ G P P +W + + R ++ ++ T
Sbjct: 10317 ELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPAT 10376
Query: 538 LTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW 593
L + ++ +DSG Y VEN G + V V P PP+ ++ + D + + W
Sbjct: 10377 LALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW 10436
Query: 594 SDQ-GDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
DGGS I Y+I K D W + + + + L G Y I A N G
Sbjct: 10437 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYG 10496
Query: 652 TGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMS 709
P D + A + VP P + + + V + DGG I +++E RE
Sbjct: 10497 ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETM 10556
Query: 710 QPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ F V L Y+ R++A N G
Sbjct: 10557 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIG 10596
Score = 108 bits (260), Expect = 9e-23
Identities = 122/487 (25%), Positives = 195/487 (40%), Gaps = 32/487 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P PP L+ ++ SV ++W+PP + G + I + Y V T A +
Sbjct: 15453 DTPG-PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKREST-----RKAYSTVA 15505
Query: 341 SGLHTT---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ H T + L+ +Y V A G G+ A + P P I +R
Sbjct: 15506 TNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTR 15565
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
N + +SW P G ++GY + M + ++ +T++ +
Sbjct: 15566 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEE----YS 15621
Query: 457 FWVSASTRLGEGEATRV-VTVLPSDSV-PARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
F VSA G + ++ V V+ D V P E++ + +G P PA
Sbjct: 15622 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPA 15681
Query: 515 TTWTMNGVGLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + V L+ T R N S + LTI D G+Y + N G T V V
Sbjct: 15682 VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVL 15741
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEELQVEAGT 626
P PP + + + ADS+ L W + DGGS I Y++ KR+ W+ +
Sbjct: 15742 DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE-KRDTSTTTWQIVSATVAR 15800
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG--TGLPCDIVHAYTKGTVPVKPKHSQMITLNT--T 682
+ L G YQ I A NR G T L + A VP P + ++TL++ +
Sbjct: 15801 TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDS 15859
Query: 683 TVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
W + DGG ++ + +E +E + W + N + F +GL Y+ R+
Sbjct: 15860 MEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTKFKTTGLEEGVEYEFRV 15918
Query: 743 TAHNNAG 749
+A N G
Sbjct: 15919 SAENIVG 15925
Score = 105 bits (253), Expect = 7e-22
Identities = 108/394 (27%), Positives = 164/394 (41%), Gaps = 19/394 (4%)
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEG 431
PV+ PS P + +A ++ N + ++W PP G ++GY + Y V ++
Sbjct: 10606 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 10665
Query: 432 THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VLPSDSV--PARI-- 486
H P T ++ + T++F V A GE + V VL D + P I
Sbjct: 10666 NHTPESCPET-KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILD 10724
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQS 545
+ +R + + LS GVP P TW + R +V+ G+ L I
Sbjct: 10725 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAH 10784
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPI 603
D G Y+ +VEN G V+ V V P PP L V + DS +L W + DGGS I
Sbjct: 10785 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 10844
Query: 604 LGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---V 659
YV+ + W L + H +L G +Y + A N+ G G + +
Sbjct: 10845 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 10904
Query: 660 HAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN 718
A P PK + ++ T V+ VW DGG I +++EY+E W +
Sbjct: 10905 KALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW-IKFK 10963
Query: 719 SVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+V E V V+GL Y+ R+ A N G L
Sbjct: 10964 TVTNLECV--VTGLQQGKTYRFRVKAENIVGLGL 10995
Score = 105 bits (253), Expect = 7e-22
Identities = 161/683 (23%), Positives = 267/683 (39%), Gaps = 54/683 (7%)
Query: 95 AGNSPIINYI-VQYKEAPESWPSTPQKVIVPGSVT------SASVQNLQPAT---SYHLR 144
AG++ ++N I + K P+S S K I P +T ++S+ ++ AT +
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 13954
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I A N G + V+VT + VP GPP V + S+ + +TW PP D G+ +
Sbjct: 13955 ITATNPFGTKV--EHVKVTVLD-VP-GPPGPVEISNVSAEKATLTWTPPLED--GGSPIK 14008
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y+ L T S + TV R + L + Y V A N
Sbjct: 14009 SYI----LEKRET----------SRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNH 14054
Query: 265 RXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
++ P PP + + ++ + VSW+ P G + I GY V
Sbjct: 14055 YGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEIT-GYHVER 14113
Query: 324 APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV 383
A+ +S L ++GL+ + Y V A AG G + +D
Sbjct: 14114 REKKSLRWVR-AIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 14172
Query: 384 ---PSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLS 438
P P++ +++ ++W P G+ + GY + + V ++ + T L
Sbjct: 14173 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 14232
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLPSDSVP--ARITSFSRNIV 494
+ ++ + + F +SA G GE + V ++ + P R +V
Sbjct: 14233 ITQFVVPDLQTKEK--YNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLV 14290
Query: 495 TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSADSGNYTC 553
+I + G PAP TWT + + L++ +N S L I D+G +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14350
Query: 554 SVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYK 611
++EN G+ V V P P + L D DS+ L W DGGS I Y++ K
Sbjct: 14351 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVE-K 14409
Query: 612 RE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV 669
RE + + + + L G Y + A N G G P + P
Sbjct: 14410 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 14469
Query: 670 KPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
P ++ + +TV++ W DGG I +VIE + QW ++ +V+ E V
Sbjct: 14470 PPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT-TVKGLECV-- 14526
Query: 729 VSGLTPAAHYQLRITAHNNAGHA 751
V LT Y ++ A N+AG +
Sbjct: 14527 VRNLTEGEEYTFQVMAVNSAGRS 14549
Score = 104 bits (249), Expect = 2e-21
Identities = 115/486 (23%), Positives = 191/486 (39%), Gaps = 35/486 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PP L+ + + S ++W+ P G ++ Y V V + + T + H
Sbjct: 10815 PPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVASAQWSPLSATSKKKS-HF 10872
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
L Y V A G G P+ P P D+ + ++ +
Sbjct: 10873 A-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSL 10931
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK--RMLSPSTLSHETSRSPPRATHQFWV 459
W P G + GY + + +EEGT + + + L + T++F V
Sbjct: 10932 VWNKPDRDGGSPITGYLV------EYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRV 10985
Query: 460 SASTRLGEGEATRVVTVLPSDS-VPARI---TSFSRNIVTPWKENISLSCNKVGVPAPAT 515
A +G G + + + VP + +V + GVP P
Sbjct: 10986 KAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 11045
Query: 516 TWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
WT +G +++ V +D LTI D+G Y +V N G V + V
Sbjct: 11046 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105
Query: 573 PPQPPI--LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSE 628
P PP + ++D + + + W + DGGSP++ Y++ + D W + + ++
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11165
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTT 683
+P+L G Y + A N+IG G P D H ++ + P KP + IT N T
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAAT 11224
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
V+ W DGG I + +E RE++ +W V N + F V+GL Y+ R+
Sbjct: 11225 VS-WTLPKSDGGSPITGYYMERREVT-GKWVRV-NKTPIADLKFRVTGLYEGNTYEFRVF 11281
Query: 744 AHNNAG 749
A N AG
Sbjct: 11282 AENLAG 11287
Score = 103 bits (248), Expect = 3e-21
Identities = 155/634 (24%), Positives = 249/634 (39%), Gaps = 64/634 (10%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
++ EN+ G+ V+V + P GP + ++ +S + V+W PP D +ILG
Sbjct: 23710 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRS---VRVSWRPPADD-GGADILG 23765
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN- 263
Y + +E+ P A YT+ + GT+ + GL+++ Y V A N
Sbjct: 23766 YILERREV-----------PKAAWYTIDS-RVRGTS---LVVKGLKENVEYHFRVSAENQ 23810
Query: 264 ---SRXXXXXXXXXXXXXME--DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
S+ + + PS PP L ++ SV +SW P G + +
Sbjct: 23811 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSLSWSRPKDDGGSRVTGY 23867
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPV 375
Y TD + + QI+ T++GL Y + A G + PV
Sbjct: 23868 YIERKETSTDKWVRHNKT--QITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 23925
Query: 376 YCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK 434
C D PS P +++ S++ + + W P G ++GY + D + ++K
Sbjct: 23926 VCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 23985
Query: 435 RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATR----VVTVLPSDSVPARITSF 489
+ T AT ++F V A G R + T L S P I
Sbjct: 23986 ERIKDKQF---TIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKE 24041
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSA 546
+++ T E LSC VG P P W G L + + +SSDG TLT+ +
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 24101
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ-PPILAVVDSY----ADSLHLQWSDQGDGGS 601
D G YTC N G E + + ++ PQ P + + Y +L L G
Sbjct: 24102 DEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIG-RPV 24160
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEH----VLPNLWCGTRYQLY-ITAFNRIGTGLPC 656
P + + K E + +E +EH V+ N+ T Y + N GT
Sbjct: 24161 PAMTWFHGQKLLQNS-ENITIE--NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI 24217
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRL 715
V K P P + + N+ ++ W DGG I +V+E E + +W+L
Sbjct: 24218 LDVEIQDKPDKPTGPIVIEALLKNSAVIS-WKPPADDGGSWITNYVVEKCEAKEGAEWQL 24276
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
VS+++ T + LT A Y R++A N G
Sbjct: 24277 VSSAISVT--TCRIVNLTENAGYYFRVSAQNTFG 24308
Score = 101 bits (241), Expect = 2e-20
Identities = 124/508 (24%), Positives = 191/508 (37%), Gaps = 54/508 (10%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY----RVTYAPVTDWYGNEDAVTKQIS 341
PPG + A + S+ VSW PP G + I GY R +P +
Sbjct: 9104 PPGKPKVLARTKGSMLVSWTPPLDNGGSPIT-GYWLEKREEGSPYWSRVSRAPITKVGLK 9162
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRN 398
G+ + L Y A AAG G + P D P P+ + +++
Sbjct: 9163 GVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKS 9222
Query: 399 KILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTH--KRMLSPSTLSHETSRSPPRAT- 454
I + W PP+ G + GY + M +EEGT KR+ P L P
Sbjct: 9223 SISLGWKPPAKDGGSPIKGYIVEM------QEEGTTDWKRVNEPDKLITTCECVVPNLKE 9276
Query: 455 ---HQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF-----SRNIVTPWKENISLSCN 506
++F V A GE E + +P+ + F +V I +
Sbjct: 9277 LRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAV 9336
Query: 507 KVGVPAPATTWTMNGVGL-----------ESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
G P P ++W +G E + + + I + + +G Y+ +
Sbjct: 9337 IKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITA 9396
Query: 556 ENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE 613
+N G+ V+V P PP L V D S L W DGG I GYVI +
Sbjct: 9397 KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI 9456
Query: 614 HGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT------KGT 666
G W ++ + G++ V+P+L +Y + A NR G G P + + T
Sbjct: 9457 DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD 9516
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEY-----REMSQPQWRLVSNSVQ 721
P+K K +IT NT ++ W DGG + ++++E + WR N
Sbjct: 9517 PPIKLKIG-LITKNTVHLS-WKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWR-QCNKRD 9573
Query: 722 ATERVFSVSGLTPAAHYQLRITAHNNAG 749
E F+V L Y+ R+ A N AG
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAG 9601
Score = 100 bits (240), Expect = 2e-20
Identities = 152/646 (23%), Positives = 251/646 (38%), Gaps = 54/646 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS SV++ S + + A+N G+ + V+V P GP V + ++ +
Sbjct: 16102 TSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP---VVISGVTAEKCT 16158
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP +D +I+ Y V +E S V TV A ++
Sbjct: 16159 LAWKPPLQD-GGSDIINYIVERRE---------------TSRLVWTVVDANVQTLSCKVT 16202
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWE 305
L + Y + A N VP P A + ++ S+ V WE
Sbjct: 16203 KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK-APEVTTVTKDSMIVVWE 16261
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + + I L ++GL +Y V A A
Sbjct: 16262 RPASDGGSEIL-GY-VLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENA 16319
Query: 366 AGDGVRAAP-VYCHTEEDV--PSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYM 421
AG + P Y + + P P + K +R+ + +SW P G + GY +
Sbjct: 16320 AGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEK 16379
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVV-TV 476
+ G E T M +P T ++T+ + + + F + A + G GE V +
Sbjct: 16380 CDVSVG--EWT---MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPI 16434
Query: 477 LPSDSVPARITSFS---RNIVTPWKE-NISLSCNKVGVPAPATTW-TMNGVGLESTLRKN 531
+ + + A R I+ ++ L G P P W ++G ++ +
Sbjct: 16435 IVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV 16494
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLH 590
SS +L + DSG YT ++EN G TV V P PP+ L V + DS+
Sbjct: 16495 TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVS 16554
Query: 591 LQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
+ W DGGS I Y++ KRE + + + + L G Y +TA
Sbjct: 16555 ITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16613
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQM--ITLNTTTVTVWLDSWGDGGCGILYFVIEY 705
N G GLP VP P + +T N+ +++ W DGG I+ +++E
Sbjct: 16614 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS-WTKPEHDGGSKIIQYIVEM 16672
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+ +W + V++ + V ++ LT Y R+ A N G +
Sbjct: 16673 QAKHSEKWSECAR-VKSLQAV--ITNLTQGEEYLFRVVAVNEKGRS 16715
Score = 99 bits (238), Expect = 4e-20
Identities = 114/432 (26%), Positives = 175/432 (40%), Gaps = 31/432 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
++GL Y V A G G V P+ P++P + +++ I + W
Sbjct: 8759 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDW 8818
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
P S G + GY + + E +KR L P+T S ++F V A
Sbjct: 8819 KEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR-LCPTT-SFLVENLDEHQMYEFRVKAVN 8876
Query: 464 RLGEGEATRVVTV-LPSDSVPA----RITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
+GE E + + V + D VP R++ I E + + + G+P P W+
Sbjct: 8877 EIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWS 8936
Query: 519 MNGVGLESTL------RKNVS-SDGTLTISMTQSA--DSGNYTCSVENIHGRDEVTYTVE 569
N +E ++ VS S+ +S+ ++ D G YT + N G VE
Sbjct: 8937 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVE 8996
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYK---REHGDWEELQVEA 624
V P PP LAV D A+S +L W D GGS I YVI+ + R+ +WEE+ A
Sbjct: 8997 VYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTA 9056
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L +Y+ + A N+ G C D V +P P +++
Sbjct: 9057 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKG 9116
Query: 683 TVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS----VQATERVFSVSGLTPAAH 737
++ V W +GG I + +E RE P W VS + V F+V L
Sbjct: 9117 SMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVK 9176
Query: 738 YQLRITAHNNAG 749
YQ R A N AG
Sbjct: 9177 YQFRAMAINAAG 9188
Score = 99 bits (238), Expect = 4e-20
Identities = 122/491 (24%), Positives = 192/491 (39%), Gaps = 36/491 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVT 337
D P P L+ + ++ S VSW PP G G +VT+ V + VT
Sbjct: 12200 DTPG-PVSDLKVSDVTKTSCHVSWAPPENDG------GSQVTHYIVEKREADRKTWSTVT 12252
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAV 394
++ ++ L Y V A G GV PV P P ++
Sbjct: 12253 PEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTE 12312
Query: 395 SSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
++N ++WLPP G + GY E + T ++ +L + +
Sbjct: 12313 MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKK- 12371
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFSRNIVTPWKENISLSCNKVGVP 511
++F V+A +G V + +P +I + + K+ + + + G P
Sbjct: 12372 -YKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKK-LRIEAHVYGKP 12429
Query: 512 APATTWTM--NGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
P W + V S L + S L I DSG Y+ + EN G D V
Sbjct: 12430 HPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKV 12489
Query: 569 ---EVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVI-NYKREHGDWEELQVE 623
+ PPQPP + D AD+ L W DGGS I Y++ GDW
Sbjct: 12490 VVMDAPGPPQPP-FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 12548
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC---DIVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A NR G P +V + G VP +PK++++ +N
Sbjct: 12549 VTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-VPSEPKNARVTKVN 12607
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS-VQATERVFSVSGLTPAAHY 738
+ V W DGG I+ ++IE +E + W +++ V++TE + +GL Y
Sbjct: 12608 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTE--YPCAGLVEGLEY 12665
Query: 739 QLRITAHNNAG 749
RI A N AG
Sbjct: 12666 SFRIYALNKAG 12676
Score = 99.1 bits (236), Expect = 8e-20
Identities = 148/652 (22%), Positives = 258/652 (39%), Gaps = 58/652 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T+ +V++ S + EN G S V V +GP + V + S+ +
Sbjct: 22206 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP---IEVSSVSAESCV 22262
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
++W P +D I Y V +E + + L+ S R++ ++
Sbjct: 22263 LSWGEP-KDGGGTEITNYIVEKRESGTTAWQLVNSS---------------VKRTQIKVT 22306
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL---QCNALSSQSVRVSW 304
L K+ Y+ V + N + + P +PP A + +S+ ++ + W
Sbjct: 22307 HLTKYMEYSFRVSSENR--FGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRW 22364
Query: 305 EPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTL-SGLR-RYTNYSVTV 360
E P G + I+ GY V W + + T L GL ++ Y++
Sbjct: 22365 EEPYHDGGSKII-GYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL 419
+ A + R P+ D P P + +R+ + + W P+ G +VGY +
Sbjct: 22424 AGVSKASEASR--PIMAQNPVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478
Query: 420 Y---MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE----GEATR 472
+S + DGR + ++S + + + T++F V A G E+T
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFT--VTALSEGDTYEFRVLAKNAAGVISKGSESTG 22536
Query: 473 VVTVLPSDSVP-ARITS-FSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLR 529
VT + P A + + ++VT ++ L G P P WT L+ +
Sbjct: 22537 PVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 22596
Query: 530 KNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY 585
++ G T I +DSG YT +V+N G V+ V+V P P L V
Sbjct: 22597 VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVT 22656
Query: 586 ADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQL 642
+ L WS Q DGG+ I Y++ +RE +W ++ E T +V+ L Y
Sbjct: 22657 QEKCTLAWSLPQEDGGAEITHYIVE-RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIF 22715
Query: 643 YITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
+ A N+ G G+P + + A T+P P + + + + W DGG I
Sbjct: 22716 RVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 22775
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
++++ RE +W V+ + V+ L YQ R+TA N AG++
Sbjct: 22776 NYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNS 22827
Score = 98.7 bits (235), Expect = 1e-19
Identities = 146/663 (22%), Positives = 262/663 (39%), Gaps = 59/663 (8%)
Query: 118 PQKVIVPGSVTSAS--VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ+ + + S+S ++N Q + ++A+N G+ + + V V P G P
Sbjct: 10069 PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFL 10127
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
S +L TW P+ D I Y + +E + + + +YTV
Sbjct: 10128 AHNLTNESCKL--TWFSPEDD-GGSPITNYVIEKRESDRRAWTPV-------TYTV---- 10173
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCN 293
R T+ GL + AY + A NS + + ++P P L+
Sbjct: 10174 ----TRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10229
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
++ +V ++W PP G + I+ + T+ + + T+ GL+
Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF--HKVTNDNLLSRKYTVKGLKEG 10287
Query: 354 TNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAVSSR--NKILVSWLPPS 408
Y V A G G + P+ C E P+ D + ++ R ++
Sbjct: 10288 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSG 10347
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
P + + V+ED R TH + +P+TL+ E ++ + ++ V G
Sbjct: 10348 KPKPKVSWFKDEADVLEDDR---THIKT-TPATLALEKIKAKRSDSGKYCVVVENSTGSR 10403
Query: 469 EATRVVTVLPSDSVPARITSFSR----NIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
+ V V+ P SF +V WK + +K+ V +
Sbjct: 10404 KGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 10463
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE--VTYTVEVK----VPPQPPI 578
T + S+ T +S + EN++G + V+ +++ K VP P
Sbjct: 10464 PVT---SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQ 10520
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD--WEELQVEA--GTSEHVLPNL 634
V + DS + W+ DGG PI Y++ KRE W + + ++ +P+L
Sbjct: 10521 PIVTEVTKDSALVTWNKPHDGGKPITNYILE-KRETMSKRWARVTKDPIHPYTKFRVPDL 10579
Query: 635 WCGTRYQLYITAFNRIGTG---LPCDIVHAYTKGTVPVKPKHSQMI--TLNTTTVTVWLD 689
G +Y+ ++A N IG G P V A P P + + I T N+ +T W
Sbjct: 10580 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT-WQP 10638
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA-TERVFSVSGLTPAAHYQLRITAHNNA 748
DGG IL +++EY+++ +WR +++ ++ E + V+GL Y+ R+ A N A
Sbjct: 10639 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 10698
Query: 749 GHA 751
G +
Sbjct: 10699 GES 10701
Score = 97.5 bits (232), Expect = 2e-19
Identities = 125/500 (25%), Positives = 198/500 (39%), Gaps = 38/500 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L+ + ++ S R+SW+ P G + I +GY + + + V
Sbjct: 9413 DVPG-PPKDLKVSDITRGSCRLSWKMPDDDGGDRI-KGYVIEKRTIDGKAWTK--VNPDC 9468
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSR 397
+ L Y V A G G + T D P P +K + ++
Sbjct: 9469 GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITK 9528
Query: 398 NKILVSWLPPSSPNGVLVGYTLYMSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRA 453
N + +SW PP + G V + + + D +E L
Sbjct: 9529 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 9588
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKE--NISLSCNKVGV 510
++F V A G + + TV P D P S +E N+++ GV
Sbjct: 9589 EYEFRVKAVNAAGVSKPS--ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGV 9646
Query: 511 PAPATTW---------TMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
P P TW V ++ + K V D TL I ++ +D+G YT + N G
Sbjct: 9647 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706
Query: 561 RDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHG-- 615
+ V P PP+ + AD + L W + DGGS I YVI KRE
Sbjct: 9707 TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE-KREANRK 9765
Query: 616 DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKPKH 673
W + E + +P L G Y I A N+ G G P D + +VP P
Sbjct: 9766 TWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDK 9825
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVS-NSVQA-TERV-FSV 729
+ ++ ++TV W + DGG + + +E ++ + +W+ V+ + ++A T V + V
Sbjct: 9826 PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKV 9885
Query: 730 SGLTPAAHYQLRITAHNNAG 749
+GL + YQ R+ A N AG
Sbjct: 9886 TGLIEGSDYQFRVYAINAAG 9905
Score = 96.7 bits (230), Expect = 4e-19
Identities = 149/717 (20%), Positives = 267/717 (37%), Gaps = 69/717 (9%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVI 122
L +VP +P + V+D T+ ++W +P Y G S + Y+++ K E W V
Sbjct: 23133 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV---VT 23189
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--------TEEVPSGPPQ 174
+ +V +V +L Y RI A+N G SEP + V T T ++ + P +
Sbjct: 23190 LKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK 23249
Query: 175 DVRVEAKSSTELI--VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
+ V A EL+ + PP W ++ G +L + V + + A T+R
Sbjct: 23250 TIHVPAGRPVELVIPIAGRPPPAASW------FFAG-SKLRESERVTVETHTKVAKLTIR 23302
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
T L + + + V + D P P G ++
Sbjct: 23303 ETTIRDTGEYTLELKNVTGTTSETIKV------------------IILDKPGPPTGPIKI 23344
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTKQISGLHTTLSGL 350
+ + + S+ +SWEPP + G L GY V A W ++VT+ + T L+
Sbjct: 23345 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESVTRS-TFKFTRLTEG 23402
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y + V G +++ + C + +P P ++ SR+ + ++W PP
Sbjct: 23403 NEYV-FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23461
Query: 411 NGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA-THQFWVSASTRLGEG 468
G V GY + + R +K P T++ S ++ V+A G G
Sbjct: 23462 GGSQVTGYIVERKEVRADRWVRVNK---VPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 23518
Query: 469 EATR-VVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGVG 523
+ +R ++ D + + + + ++SL+ ++ G M V
Sbjct: 23519 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD 23578
Query: 524 LESTLRKNVSSDGTLTISMTQSADSGNY-----TCSVENIHGRDEVTYTVEVKVPPQPPI 578
+ N + ++T Y C+ EV TV+V + P
Sbjct: 23579 QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPD 23638
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEH---VLP 632
+ + Y + + ++ PI G + + +E D + + A + H V+
Sbjct: 23639 YELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIK 23698
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWG 692
G + N+ G V P P I + + V+ W
Sbjct: 23699 EADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVS-WRPPAD 23757
Query: 693 DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG IL +++E RE+ + W + + V+ T V V GL Y R++A N G
Sbjct: 23758 DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKGLKENVEYHFRVSAENQFG 23812
Score = 96.3 bits (229), Expect = 5e-19
Identities = 161/715 (22%), Positives = 271/715 (37%), Gaps = 69/715 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P+ P +I ID + +SW P G S I NYIV+ + W + V +
Sbjct: 12498 PQPPFDISDIDADA--CSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV----TK 12551
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP-SQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
TS V L P Y R+ AENR G SEP + P V P++ RV + +
Sbjct: 12552 TSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCI 12611
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
V W+ P D I+GY + +E NS V VR+ E
Sbjct: 12612 FVAWDRPDSD-GGSPIIGYLIERKERNSLLWVK------ANDTLVRSTE--------YPC 12656
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL + Y+ + A N +P PPG + ++ +V + W
Sbjct: 12657 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MPVDPPGKPEVIDVTKSTVSLIWAR 12715
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + I+ GY V + D + + QI T +GL Y A TA
Sbjct: 12716 PKHDGGSKII-GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 12774
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ P T + P I +V+ ++ + V + + G + +S
Sbjct: 12775 VNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 12833
Query: 425 EDGR----EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+DG EG K + + + E + + + ++A G AT + VL
Sbjct: 12834 KDGTLLKPAEGI-KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 12892
Query: 481 SVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
PA + +S + W+ + +++ T + ++ VS+
Sbjct: 12893 GPPASVKINKMYSDRAMLSWEPPLEDGGSEI------TNYIVDKRETSRPNWAQVSATVP 12946
Query: 538 LTISMTQSADSGN---YTCSVENIHGRDEVTYTVEVKV-----PP---QPPILAVVDSYA 586
+T + G+ + EN +G + +T PP PP+++ +
Sbjct: 12947 ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITK-- 13004
Query: 587 DSLHLQWSDQGD-GGSPILGYVINYKREHG-DWEELQVEAGTSEHV-LPNLWCGTRYQLY 643
D + + W D GGSPI GY++ + +W ++ + + L GT Y+
Sbjct: 13005 DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFR 13064
Query: 644 ITAFNRIGTGLPCDIVH-AYTKGT--VPVKPKHSQMITLNTTTVTVWLDSWG----DGGC 696
+TA N+ G G P D AY + P P ++ ++V++ SWG DGG
Sbjct: 13065 VTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSVSL---SWGKPAYDGGS 13121
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
I+ +++E + W + + F V+GL YQ R+ A N G++
Sbjct: 13122 PIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 13176
Score = 96.3 bits (229), Expect = 5e-19
Identities = 120/487 (24%), Positives = 189/487 (38%), Gaps = 34/487 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGL 343
PP ++ +S+ V W P G + ++ GY + W V +
Sbjct: 20175 PPSTPWVTNVTRESITVGWHEPVSNGGSAVV-GYHLEMKDRNSILWQKANKLVIRTTHFK 20233
Query: 344 HTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT+S GL Y V A AAG G + P D P +++ S+N + +
Sbjct: 20234 VTTISAGLI----YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSL 20289
Query: 403 SWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
SW P+ G + GY + + DGR T + + S + ++F V A
Sbjct: 20290 SWQQPAFDGGSKITGYIVERRDLPDGR--WTKASFTNVTETQFIISGLTQNSQYEFRVFA 20347
Query: 462 STRLGE----GEATRVVTVLPSDSVPARITSFSRNIVTPWK--ENISLSCNKVGVPAPAT 515
+G E +T + S P V ++ ++ L G PAP
Sbjct: 20348 RNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTI 20407
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVTYTVEVKV 572
W + L++ V + L + + AD SG Y + N G T V++
Sbjct: 20408 EWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILD 20467
Query: 573 PPQPP--ILAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKREHGDWEELQVEAGTSEH 629
P PP + A+ + L W DGG+ I Y++ KRE V E
Sbjct: 20468 KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE-KRETSRVVWSMVSEHLEEC 20526
Query: 630 VL--PNLWCGTRYQLYITAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQM--ITLNTTT 683
++ + G Y + A N+ G G P D V A P P ++ IT N+ T
Sbjct: 20527 IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMT 20586
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V VW DGG I + +E R+ W +++ +++ T + V+GLT + YQ R+
Sbjct: 20587 V-VWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ--KVTGLTENSDYQYRV 20643
Query: 743 TAHNNAG 749
A N AG
Sbjct: 20644 CAVNAAG 20650
Score = 95.1 bits (226), Expect = 1e-18
Identities = 118/485 (24%), Positives = 192/485 (39%), Gaps = 28/485 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQI 340
P PP + ++ S+ V W P G + I+ Y V D G K +
Sbjct: 15157 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN-YIVERR---DKAGQRWIKCNKKTL 15212
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA--APVY--CHTEEDVPSAPADIKAAVSS 396
+ L +SGL Y + A AAG + +P Y C T P P + + +S
Sbjct: 15213 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFK-PGPPGNPRVLDTS 15271
Query: 397 RNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
R+ I ++W P G + GY + +++ E+ + +T S+ + +
Sbjct: 15272 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT-SYTITGLTENQEY 15330
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFS--RNIVTPWKE-NISLSCNKVGV 510
+ + A G GE V ++ +P I + R +VT + L G
Sbjct: 15331 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 15390
Query: 511 PAPATTWTMN-GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
PAP W + G L+ ++ SS L + DSG Y +VEN G V
Sbjct: 15391 PAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVR 15450
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P PP L V + S+ L W DGGS I Y++ KRE + +
Sbjct: 15451 VLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCH 15509
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ + L G Y + A N G GLP + + P+ P ++ + +V+
Sbjct: 15510 KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVS 15569
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG IL +++E + +W + +V+ TE +++GL Y R++A
Sbjct: 15570 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA-TVKVTEA--TITGLIQGEEYSFRVSA 15626
Query: 745 HNNAG 749
N G
Sbjct: 15627 QNEKG 15631
Score = 93.9 bits (223), Expect = 3e-18
Identities = 134/613 (21%), Positives = 230/613 (37%), Gaps = 52/613 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T +VP P + + + + ++W+PP+ D ++ Y V Q+ ++ +++SG
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDD-GGSPVINYIVEKQDTRKDTWGVVSSG 11160
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV- 282
+++++ + LQK Y V+A N
Sbjct: 11161 ---------------SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFS 11205
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ-IS 341
P PPG ++ + VSW P G + I GY + VT G V K I+
Sbjct: 11206 PPSPPGKPVVTDITENAATVSWTLPKSDGGSPIT-GYYMERREVT---GKWVRVNKTPIA 11261
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
L ++GL Y V A AG + P+ P P + K SR
Sbjct: 11262 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRE 11321
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT--- 454
+ W P S G ++GY V+E + ++ L + + P
Sbjct: 11322 TADLVWTKPLSDGGSPILGY-----VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGN 11376
Query: 455 -HQFWVSASTRLGEGEATRVV-TVLPSDSV---PARITSFSRNIVTPWK-ENISLSCNKV 508
++F + A+ +GEGE + +V+ D + + R+++T + I +
Sbjct: 11377 EYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK 11436
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSD---GTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TWT G L R ++ D L I AD G Y S +N G + +
Sbjct: 11437 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11496
Query: 566 YTVEVKVPPQP-PILAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKREHGDWEELQVE 623
V V P P L V + ++ + W + D GGS I +++ Y++ + +
Sbjct: 11497 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 11556
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
T + NL Y + A N++G G + + A P +P++ +
Sbjct: 11557 DVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKG 11616
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHY 738
T V + W DGG L + +E R W R+ S++ T + V Y
Sbjct: 11617 KTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETH--YMVDRCVENQIY 11674
Query: 739 QLRITAHNNAGHA 751
+ R+ N G +
Sbjct: 11675 EFRVQTKNEGGES 11687
Score = 92.3 bits (219), Expect = 9e-18
Identities = 141/624 (22%), Positives = 238/624 (38%), Gaps = 59/624 (9%)
Query: 148 ENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
EN G+ E + V+V T GPP +V V+ S VTWEPP D I+ Y V
Sbjct: 13272 ENSCGKKEYTIVVKVLDTP----GPPVNVTVKEISKDSAYVTWEPPIID-GGSPIINYVV 13326
Query: 208 GFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXX 267
++ S + + S+ V + L++ +Y V A N
Sbjct: 13327 QKRDAERKSWSTVTTECSKTSFRV---------------ANLEEGKSYFFRVFAENEYGI 13371
Query: 268 XXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVT 327
P P L+ ++S S + W+ P G + I+ GY V +
Sbjct: 13372 GDPGETRDAVKASQTPG-PVVDLKVRSVSKSSCSIGWKKPHSDGGSRII-GYVVDFLTEE 13429
Query: 328 DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP 387
+ + V K +S L + L Y+ V A G+G + + +DV +
Sbjct: 13430 NKW---QRVMKSLS-LQYSAKDLTEGKEYTFRVSAENENGEGT-PSEITVVARDDVVAPD 13484
Query: 388 ADIKAA-----VSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
D+K ++ N +P V + + ++ + +
Sbjct: 13485 LDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLI 13544
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENIS 502
++ +S ++ ++ G E T + V+ +P F VT +
Sbjct: 13545 VYDCQKSD---AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDE--VTAEAMTLK 13599
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL---TISMTQSADSGNYT--CSVEN 557
+ K + T + + +S K V+ + T +T+ + YT S EN
Sbjct: 13600 WAPPKDDGGSEITNYILEK--RDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAEN 13657
Query: 558 IHGRDEVTYTVEV------KVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINY 610
+G E + + VP PP +VD DS+ L W+D + GGSPI GY + +
Sbjct: 13658 KYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEF 13717
Query: 611 KREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG---LPCDIVHAYTKG 665
K + W+ + + + L G Y+ + A N G G LP + V A
Sbjct: 13718 KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPI 13777
Query: 666 TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATER 725
P KP+ IT N+ T+ +W + DGG + +++E R++ W + +N V E
Sbjct: 13778 DPPGKPEVIN-ITRNSVTL-IWTEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPEC 13834
Query: 726 VFSVSGLTPAAHYQLRITAHNNAG 749
F+V+ L Y+ RI A N AG
Sbjct: 13835 AFTVTDLVEGGKYEFRIRAKNTAG 13858
Score = 85.0 bits (201), Expect = 1e-15
Identities = 144/628 (22%), Positives = 236/628 (37%), Gaps = 65/628 (10%)
Query: 150 RLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGF 209
+L S S+ VT GPPQ++ V+ + WEPP D + Y +
Sbjct: 17599 KLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDK 17657
Query: 210 QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXX 269
+E + ++S S+ V L + A Y V A N
Sbjct: 17658 RESTRKAYANVSSKCSKTSFKVEN---------------LTEGAIYYFRVMAENEFGVGV 17702
Query: 270 XXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW 329
+ PS PPG + +S S + WE P G + +L GY V P
Sbjct: 17703 PVETVDAVKAAEPPS-PPGKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVVEMQPK--- 17757
Query: 330 YGNED-AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPS 385
G E ++ + + ++GL Y V A+ G V PV PS
Sbjct: 17758 -GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPS 17816
Query: 386 APA-----DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPS 440
I+A + +I V P + + V G L + + E T S
Sbjct: 17817 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT-------S 17869
Query: 441 TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL--PSDSV-PARITSFSRN-IVTP 496
T+ H ++ V+A+ G V VL P V P R S + +V
Sbjct: 17870 TVLH-IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 17928
Query: 497 WKENISLS-C---NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
W+ C N + TT T + V +T+ + T+ I+ ++ +
Sbjct: 17929 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVS--ATVART-----TIKITKLKTGTEYQFR 17981
Query: 553 CSVENIHGRDEV--TYTVEVKVP---PQPPILAVVDSYA-DSLHLQWSDQ-GDGGSPILG 605
EN +G+ + V V+ P P PP V S + D + +QW + DGG+ I+G
Sbjct: 17982 IFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIG 18041
Query: 606 YVINYKREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + K ++ W +L + ++ L G Y+ ++A N +G G P + +
Sbjct: 18042 YHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV 18101
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
P + I + VT+ W DGG I +++E +++ +W + ++
Sbjct: 18102 ARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW-MKASFTNV 18160
Query: 723 TERVFSVSGLTPAAHYQLRITAHNNAGH 750
E F+VSGL Y+ R+ A N AG+
Sbjct: 18161 LETEFTVSGLVEDQRYEFRVIARNAAGN 18188
Score = 83.8 bits (198), Expect = 3e-15
Identities = 138/603 (22%), Positives = 226/603 (37%), Gaps = 55/603 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P++++V + ++ ++W P G S I NYIV+ +E+ ST V T
Sbjct: 15455 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST---VATNCHKT 15511
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V LQ SY+ R++AEN G P++ + E P PP + + + + +
Sbjct: 15512 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL-PPGKITLMDVTRNSVSL 15570
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+WE P+ D ILGY V Q S+ A TV+ E T++G
Sbjct: 15571 SWEKPEHD-GGSRILGYIVEMQTKGSDKWATCA--------TVKVTE--------ATITG 15613
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L + Y+ V A N + +D+ P L N + + P
Sbjct: 15614 LIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVP 15673
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GR + P+ +A + + + L T R + V V +AG+
Sbjct: 15674 FIGRPTPAVTWHKDNVPLKQ-TTRVNAESTENNSLLTIKDACREDVGHYV-VKLTNSAGE 15731
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
+ V + P+ P +K + + I +SW PP G + + I + R
Sbjct: 15732 AIETLNVIVLDKPGPPTGP--VKMDEVTADSITLSWGPPKYDGGSSIN-----NYIVEKR 15784
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRAT---HQFWVSASTRLG-------EGEATRVVTVLP 478
+ T + +T++ T ++ T +QF ++A R G E + +P
Sbjct: 15785 DTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP 15844
Query: 479 SDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
+T SR ++ W E IS ++V + N + L L K
Sbjct: 15845 GPPGTPVVTLSSRDSMEVQWNEPISDGGSRV-IGYHLERKERNSI-LWVKLNKTPIPQTK 15902
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVVDSYADSLHL 591
+ + + S ENI G + + E V PP P +V +S+ L
Sbjct: 15903 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVT--RNSVTL 15960
Query: 592 QWSDQG-DGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
QW DGGS I GY++ K G W + H + L RY+ + A N
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 16020
Query: 649 RIG 651
G
Sbjct: 16021 AAG 16023
Score = 83.4 bits (197), Expect = 4e-15
Identities = 143/705 (20%), Positives = 258/705 (36%), Gaps = 52/705 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQKVIVPGS 126
+VP+ P V + + ++W +P+ G PI NYI++ +E + W + I P
Sbjct: 10513 RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP-- 10570
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST-- 184
T V +L Y R+ AEN +G +PS P + ++ + P V EA +T
Sbjct: 10571 YTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCN 10630
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ +TW+PP+ D ILGY V +Q++ A++T + ++
Sbjct: 10631 SVDLTWQPPRHD-GGSKILGYIVEYQKVGDEEW-------RRANHTPES-----CPETKY 10677
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++GL+ Y V A N+ ++D P L N Q ++V
Sbjct: 10678 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVG- 10736
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK---QISGLHTTLSGLRRYTNYSVTVC 361
+R + I++G V + VT + DA TK ++ + + L +R + +
Sbjct: 10737 --DTLR-LSAIIKG--VPFPKVTWKKEDRDAPTKARIDVTPVGSKLE-IRNAAHEDGGIY 10790
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
+ T D P P D++ + ++ ++W P G ++ T Y+
Sbjct: 10791 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI--TNYV 10848
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTVLP 478
D + SH + F V+A + G G E + + L
Sbjct: 10849 VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 10908
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVGLESTLRKNVSS 534
P V K +SL NK G P G + ++ +
Sbjct: 10909 PLHPPGPPKDLHH--VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVT 10966
Query: 535 DGTLTISMTQSADSGNYTCSVENI--HGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQ 592
+ ++ Q + + ENI G + T +E + PP + + + L ++
Sbjct: 10967 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVK 11026
Query: 593 WSDQGDGGSPILGYVINYKREHGDWEELQ------VEAGTSEHVLPNLWCGTR--YQLYI 644
+ I G + + D E++ VE VL C R + I
Sbjct: 11027 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIE 704
T N G+ + P P + +T T++ W DGG ++ +++E
Sbjct: 11087 TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS-WQPPKDDGGSPVINYIVE 11145
Query: 705 YREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + W +VS+ T+ + L Y R+ A N G
Sbjct: 11146 KQDTRKDTWGVVSSGSSKTK--LKIPHLQKGCEYVFRVRAENKIG 11188
Score = 82.2 bits (194), Expect = 9e-15
Identities = 65/247 (26%), Positives = 107/247 (43%), Gaps = 9/247 (3%)
Query: 511 PAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
P W L + + + I + D G Y ++N HG+ E ++V
Sbjct: 6530 PKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV 6589
Query: 571 -KVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKR-EHGDWEELQVEAGTS 627
VP L V +++ + L W + DGGS I+GYV+ + + W A +
Sbjct: 6590 IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC 6649
Query: 628 EHVLPNLW-CGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTT 683
E + L G Y ++A NR+GTG P + V A +K VP P + + +N
Sbjct: 6650 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFG 6709
Query: 684 VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V++ W DGG I +VIE R+ + +W + +V+A + +V+ + Y R+
Sbjct: 6710 VSLTWEPPEYDGGAEITNYVIELRDKTSIRWD-TAMTVRAEDLSATVTDVVEGQEYSFRV 6768
Query: 743 TAHNNAG 749
A N G
Sbjct: 6769 RAQNRIG 6775
Score = 81.4 bits (192), Expect = 2e-14
Identities = 122/561 (21%), Positives = 210/561 (37%), Gaps = 45/561 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N+ + + + ++ +SW P G + I NYIV+ +E +T + + T
Sbjct: 18702 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT---ITNNCTKT 18758
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+ ++NLQ SY+ R++A N G P++ + E P P + V+ +T I
Sbjct: 18759 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI- 18817
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
WE P+ D I GY V Q S V+T+E T+SG
Sbjct: 18818 KWEKPESD-GGSKITGYVVEMQTKGSEK--------WSTCTQVKTLE--------ATISG 18860
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L Y V A N + D+ P L + + ++ P
Sbjct: 18861 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 18920
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+GR +R + + + +K ++ L + Y +C +AG
Sbjct: 18921 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE--LCVSNSAGS 18978
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
P+ D P P I+ S + I +SW PP G + + Y+ ++
Sbjct: 18979 --ITVPITI-IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQI--SNYIVEKKETT 19033
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE---GEATRVVTVLP-----SD 480
H + + S + R + +QF V A R G+ E++ VV P
Sbjct: 19034 STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPP 19093
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
P + + ++ W+ ++ ++ V + L S K + +D + +
Sbjct: 19094 GTPKVVHATKSTMLVTWQVPVNDGGSR--VIGYHLEYKERSSILWSKANKILIADTQMKV 19151
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVE---VKVPPQPPILAVVDSYA-DSLHLQWS-D 595
S Y ENI G + + + E + P PP V + S+ L+WS
Sbjct: 19152 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKP 19211
Query: 596 QGDGGSPILGYVINYKREHGD 616
DGG+ I GY++ +RE D
Sbjct: 19212 HYDGGAKITGYIVE-RRELPD 19231
Score = 81.0 bits (191), Expect = 2e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 36/308 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
PE P + D Q R++++SW P G + I+ YI++ +E P++ W + +V
Sbjct: 23734 PEGP--LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV----RG 23787
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTT---TEEVPSGPPQDVRVEAK 181
TS V+ L+ YH R+ AEN+ G S+P +PV T E PS PP+ + V K
Sbjct: 23788 TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV-TK 23846
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
SS L +W P+ D + GYY+ +E +++ V + T T
Sbjct: 23847 SSVSL--SWSRPKDD-GGSRVTGYYIERKETSTDKWV-------RHNKTQITT------- 23889
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQS 299
+ T++GL A Y + A N +D P PG L+ ++S S
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 23949
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
V + WE P G IL GY V Y D + + ++I T+ GL T Y
Sbjct: 23950 VTLQWEKPECDGGKEIL-GYWVEYRQSGD-SAWKKSNKERIKDKQFTIGGLLEATEYEFR 24007
Query: 360 VCAFTAAG 367
V A G
Sbjct: 24008 VFAENETG 24015
Score = 77.8 bits (183), Expect = 2e-13
Identities = 147/655 (22%), Positives = 236/655 (36%), Gaps = 78/655 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P + D + + ++W P G S I NY+V+ + E W V
Sbjct: 7287 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV----KD 7342
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTEL 186
T+ L P Y R+ AEN G EP Q +T + P GPP + + +
Sbjct: 7343 TNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAV 7402
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP-GGASYTVRTVEGAGTARSRTT 245
+TW P D I GY+V + +++ V P +Y V+
Sbjct: 7403 TLTWCEPDDD-GGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVK------------- 7448
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
GL Y V A N ++D P PPG + SVR++
Sbjct: 7449 --GLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLN 7506
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G ++ Y + G ++ V + G+ TT L GL YS V
Sbjct: 7507 WTKPEHDG-GAKIESYVIEMLKT----GTDEWV-RVAEGVPTTQHLLPGLMEGQEYSFRV 7560
Query: 361 CAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
A AG+ + PV C + PS P ++ ++N + W P G +
Sbjct: 7561 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPI-- 7618
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV-TV 476
T Y+ D R +G + + + + F V+A +G+ + T + +V
Sbjct: 7619 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSV 7678
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAP----------ATTWTMNG- 521
L D+ ++ +V K ++ L N G P T W G
Sbjct: 7679 LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGK 7738
Query: 522 -VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-L 579
G + R +GT + A++ V + E+ + PP PP+ L
Sbjct: 7739 TAGPDCNFRVTDVIEGT-EVQFQVRAEN---EAGVGHPSEPTEILSIEDPTSPPSPPLDL 7794
Query: 580 AVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHGD-WEEL------QVEAGTSEHVL 631
V D+ + + W + +GGSPI+GY + + W + ++ E V+
Sbjct: 7795 HVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVV 7854
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV 686
P+ Y L + A N IG P +I ++ V P I L T + V
Sbjct: 7855 PD----KEYVLRVRAVNAIGVSEPSEI----SENVVAKDPDCKPTIDLETHDIIV 7901
Score = 77.8 bits (183), Expect = 2e-13
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 8/142 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N+ V + + ++W P G SPIINY+VQ ++A +SW + V S
Sbjct: 13290 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST----VTTECSK 13345
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS V NL+ SY R+ AEN G +P + + P GP D++V + S +
Sbjct: 13346 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSCS 13404
Query: 188 VTWEPPQRDLWNGNILGYYVGF 209
+ W+ P D I+GY V F
Sbjct: 13405 IGWKKPHSD-GGSRIIGYVVDF 13425
Score = 76.2 bits (179), Expect = 6e-13
Identities = 87/323 (26%), Positives = 130/323 (40%), Gaps = 29/323 (8%)
Query: 76 IRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
+R + + + ISW P Y G I NYIV+ ++ + T V + T+ +
Sbjct: 17915 VRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTT---TWHMVSATVARTTIKITK 17971
Query: 135 LQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
L+ T Y RI AENR G+S P S+ V V + P GPP V + S +++V W
Sbjct: 17972 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP-GPPGTPFVTSISKDQMLVQWHE 18030
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
P D I+GY++ +E NS V + P + +TT GL +
Sbjct: 18031 PVND-GGTKIIGYHLEQKEKNSILWVKLNKTP------------IQDTKFKTT--GLDEG 18075
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y V A N D P PPG + ++ +V + W+ P G
Sbjct: 18076 LEYEFKVSAENIVGIGKPSKVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYDGG 18134
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD---- 368
+ I GY V + D + + T + T+SGL Y V A AAG+
Sbjct: 18135 SKI-TGYIVEKKDLPDGRWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAGNFSEP 18192
Query: 369 GVRAAPVYCHTEEDVPSAPADIK 391
+ + E D P+A D K
Sbjct: 18193 SDSSGAITARDEIDAPNASLDPK 18215
Score = 72.9 bits (171), Expect = 6e-12
Identities = 87/368 (23%), Positives = 141/368 (38%), Gaps = 25/368 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P+ + ++ TI + W +P + G SPI YI++ + + K + P T
Sbjct: 8798 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCP--TT 8855
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT-TTEEVPSGPPQDVRVEAKSSTELI 187
S V+NL Y R+ A N +G+SEPS P+ V +EVP P +R+ + T +
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP--PTIKLRLSVRGDTIKV 8913
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
EP ++ G + E + N TV+ P A + A++ ++
Sbjct: 8914 KAGEPVHIP---ADVTGLPMPKIEWSKNETVI--EKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ V A N + D PS PP L + ++S ++W+ P
Sbjct: 8969 KAVREDKGTYTVTASN---RLGSVFRNVHVEVYDRPS-PPRNLAVTDIKAESCYLTWDAP 9024
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I Y + + + VT + L Y V A G
Sbjct: 9025 LDNGGSEITH-YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 9083
Query: 368 --DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSVI 424
D ++ V +P P K ++ +LVSW PP G + GY L
Sbjct: 9084 ISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWL----- 9138
Query: 425 EDGREEGT 432
+ REEG+
Sbjct: 9139 -EKREEGS 9145
Score = 72.5 bits (170), Expect = 8e-12
Identities = 62/259 (23%), Positives = 104/259 (40%), Gaps = 18/259 (6%)
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGT------LTISMTQSADSGNYTCSVENIHGR 561
+G P PA TW L+++ +N++ + T + ++ + +G Y + N+ G
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNS--ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24213
Query: 562 DEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQGD-GGSPILGYVINY--KREHGD 616
+ VE++ P P +V +S + W D GGS I YV+ +E +
Sbjct: 24214 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 24273
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
W+ + + + NL Y ++A N G P ++ + KP
Sbjct: 24274 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGK 24333
Query: 677 ITLNTTT----VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
T+ T V W DGG I + +E RE Q +W V+ + E VFSV L
Sbjct: 24334 PTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSVKNL 24392
Query: 733 TPAAHYQLRITAHNNAGHA 751
Y+ R+ N G +
Sbjct: 24393 IEGLEYEFRVKCENLGGES 24411
Score = 72.1 bits (169), Expect = 1e-11
Identities = 114/499 (22%), Positives = 193/499 (38%), Gaps = 44/499 (8%)
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE-DAVT 337
++D P P G + AL S +SW+PP G + I Y V + G E V+
Sbjct: 24222 IQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWI-TNYVVEKCEAKE--GAEWQLVS 24278
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVR-AAPVYCHTEEDVPSAPADIKAAV 394
IS + L Y V A G D + ++ V + + P AP
Sbjct: 24279 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 24338
Query: 395 SSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR-- 452
+++ +V+W PP+S G + Y+ + RE+ +K + + ET S
Sbjct: 24339 VTKDSCVVAWKPPASDGGAKI-RNYYL----EKREKKQNKWISVTTEEIRETVFSVKNLI 24393
Query: 453 --ATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFS---RNIVTPWKENISLSCN 506
++F V GE E + + + P VP + F RN+ ++ N +L C
Sbjct: 24394 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 24453
Query: 507 KVGVPAPATTWTMNGV-----GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
G P P W G GL+ +++ L I+ D+ Y N G
Sbjct: 24454 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS 24513
Query: 562 DEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKR------ 612
T ++EV+VP + + ++ ++H + P G VI +++
Sbjct: 24514 VSGTASLEVEVPAKIHLPKTLEGMG-AVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 24572
Query: 613 EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYIT-AFNRIGTGLPCDIVHAYTKGTVPVKP 671
+G ++ + + TS V PN Y+ A NR G + VP P
Sbjct: 24573 NNGHYQVIVTRSFTS-LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV---ADVPDPP 24628
Query: 672 KHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVS 730
+ ++ ++ +V + W + DGG I +++E + +W V QA E ++V
Sbjct: 24629 RGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG---QARETRYTVI 24685
Query: 731 GLTPAAHYQLRITAHNNAG 749
L YQ R+ A N G
Sbjct: 24686 NLFGKTSYQFRVIAENKFG 24704
Score = 70.5 bits (165), Expect = 3e-11
Identities = 63/210 (30%), Positives = 86/210 (40%), Gaps = 8/210 (3%)
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQ-GDGGSPIL 604
D G Y VEN HG + TV V P PPI V D S+ +W DGGS I+
Sbjct: 8278 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEII 8337
Query: 605 GYVINYKREHGDWEELQVEAGTSEHV---LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y + K + E V T H + L G Y + A NR G G PC
Sbjct: 8338 NYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL 8397
Query: 662 YTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
K P P + + + ++ V + D G IL + +E RE++ W V+ S
Sbjct: 8398 VAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKS 8457
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + +V GL Y R+ A N AG
Sbjct: 8458 LLNALKA-NVDGLLEGLTYVFRVCAENAAG 8486
Score = 69.3 bits (162), Expect = 7e-11
Identities = 86/333 (25%), Positives = 135/333 (40%), Gaps = 38/333 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N D + ++ W P G S IINY ++ K+ + P + + ++V ++
Sbjct: 8305 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTK--PDS-EWIVVTSTLR 8361
Query: 129 SA--SVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSST 184
SV L Y R+ AENR G P S+P+ P P + + VE +S
Sbjct: 8362 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPI-VEDVTSN 8420
Query: 185 ELIVTWEPPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
++V W P+ NG+ ILGY++ +E+NS S +++ A +
Sbjct: 8421 SMLVKWNEPKD---NGSPILGYWLEKREVNSTHW----------SRVNKSLLNA----LK 8463
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVR 301
+ GL + Y V A N+ D P PPG + SS ++
Sbjct: 8464 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIE 8522
Query: 302 VSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
+ WEPP G G + GY V V +W K I T+ +R +Y +
Sbjct: 8523 LEWEPPAFNG-GGEIVGYFVDKQLVGTNEW---SRCTEKMIKVRQYTVKEIREGADYKLR 8578
Query: 360 VCAFTAAGDGV--RAAPVYCHTEEDVPSAPADI 390
V A AAG+G PV ++ P+ D+
Sbjct: 8579 VSAVNAAGEGPPGETQPVTVAEPQEPPAVELDV 8611
Score = 69.3 bits (162), Expect = 7e-11
Identities = 135/600 (22%), Positives = 233/600 (38%), Gaps = 65/600 (10%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+SW P G S I NY+++ +EA ++W + P T ++ L Y RI
Sbjct: 9739 LSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSE---PKECTY-TIPKLLEGHEYVFRI 9794
Query: 146 IAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
+A+N+ G EP S+P VP G P V + + + V WE P+ D +
Sbjct: 9795 MAQNKYGIGEPLDSEPETARNLFSVP-GAPDKPTVSSVTRNSMTVNWEEPEYD-GGSPVT 9852
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
GY++ ++ S + P ++ A T ++GL + + Y V A N
Sbjct: 9853 GYWLEMKDTTSKRWKRVNRDP------IK----AMTLGVSYKVTGLIEGSDYQFRVYAIN 9902
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGA--LQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P PPG + + S + W PP G + + GY V
Sbjct: 9903 AAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKV-TGYIV 9960
Query: 322 TYAP--VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
Y +W +D K++ G ++GL+ Y V A AG G
Sbjct: 9961 EYKEEGKEEWEKGKD---KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIE 10017
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS-----VIEDGREEGT-- 432
+D +P D++ S R++I+V G ++ Y+S + E T
Sbjct: 10018 MKDRLVSP-DLQLDASVRDRIVVH-------AGGVIRIIAYVSGKPPPTVTWNMNERTLP 10069
Query: 433 HKRMLSPSTLSHETSRSPPRATHQ--FWVSASTRLGEGEATRVVTVLPSDSVPARI-TSF 489
+ + + +S + +HQ + + A GE + T +V VL VP + T F
Sbjct: 10070 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL---DVPGPVGTPF 10126
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
+ +T ++ + +P T + + + V+ T + Q G
Sbjct: 10127 LAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQG 10186
Query: 550 N---YTCSVENIHGRDEVTYTVE-------VKVPPQPPILAVVDSYADSLHLQWS-DQGD 598
+ + EN G T E + VP +P L V + +++ L W+ + D
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246
Query: 599 GGSPILGYVINYKREHGDWEELQVEAG---TSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
GGS I+ YV+ R G + +V + ++ + L G Y+ ++A N +G G P
Sbjct: 10247 GGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10305
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP PKN RV I ++W +P + G SPII Y+++ KE W ++
Sbjct: 12594 VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLV---R 12650
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T L Y RI A N+ G S PS+P + T +P PP V + + +
Sbjct: 12651 STEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA-RMPVDPPGKPEVIDVTKSTV 12709
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP 224
+ W P+ D I+GY+V +L + V + P
Sbjct: 12710 SLIWARPKHD-GGSKIIGYFVEACKLPGDKWVRCNTAP 12746
Score = 66.1 bits (154), Expect = 7e-10
Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+ ++V D ++ ++WT+P + G S I NYIV+ E W Q
Sbjct: 24624 VPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ-----AR 24678
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
T +V NL TSY R+IAEN+ G S+PS+P + T T+E
Sbjct: 24679 ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719
Score = 64.9 bits (151), Expect = 2e-09
Identities = 72/307 (23%), Positives = 114/307 (37%), Gaps = 27/307 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
VP P + + + + ++WT P G SPI +YI++ +E W + +
Sbjct: 13975 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 14034
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
V + +Q Y R+ A N G+ EP Q V + P GPP+ V +
Sbjct: 14035 VATKLIQG----NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNT 14090
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
V+W+ P D I GY+V +E S V P + R
Sbjct: 14091 ATVSWKRPVDD-GGSEITGYHVERREKKSLRWVRAIKTP--------------VSDLRCK 14135
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
++GLQ+ + Y V A N M+D P PP + +S ++
Sbjct: 14136 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195
Query: 304 WEPPPMRGRNGI-LQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W P G G+ + GY V + V D +D + + L+ Y+ + A
Sbjct: 14196 WGKPHYDG--GLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253
Query: 363 FTAAGDG 369
AG G
Sbjct: 14254 INDAGVG 14260
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/146 (28%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
+ VP P N+ + D + ++W P Y G + I NY+++ ++ W + + V
Sbjct: 6691 YDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTA---MTVR 6747
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVPSGPPQDVRVEAK 181
SA+V ++ Y R+ A+NR+G +PS V+V E PS PP ++ +
Sbjct: 6748 AEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQ 6806
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYV 207
+ + + + WEPP +D ILGY +
Sbjct: 6807 TQSSVQLKWEPPLKD-GGSPILGYII 6831
Score = 64.1 bits (149), Expect = 3e-09
Identities = 100/411 (24%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I ++ + S T+Q W +P Y G S I YIV+ KE PE W I+
Sbjct: 15945 PGRPEAI-IVTRNSVTLQ--WKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIID--- 15998
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R+IA N G SEPS+ +T +EV PP+ + ++ K
Sbjct: 15999 THFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV--DPPR-ISMDPKYKDT 16055
Query: 186 LIV-TWE--PPQRDLWNGNI--LGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
++V E D++ I + + G QEL++ + + I S S +V+ +
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ + V V+ D P P G + + ++++
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVL------------------DRPGPPEGPVVISGVTAEKC 16157
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
++W+PP G + I+ Y V + + DA + +S T L YT +
Sbjct: 16158 TLAWKPPLQDGGSDII-NYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMA 16216
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYT 418
V + G+ + + PV VP AP + +++ ++V W P+S G ++GY
Sbjct: 16217 VNKY-GVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYV 16275
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L E R HKR++ L + ++F VSA G E
Sbjct: 16276 LEKRDKEGIRWTRCHKRLIGELRL--RVTGLIENHDYEFRVSAENAAGLSE 16324
Score = 63.7 bits (148), Expect = 3e-09
Identities = 67/260 (25%), Positives = 111/260 (42%), Gaps = 31/260 (11%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP +N+ V + + ++W +P G S II Y+V+ ++ ++W +
Sbjct: 6592 VPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRA----E 6647
Query: 127 VTSASVQNLQPA-TSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKS 182
+V LQ Y R+ A NR+G EP PV+ + +VP GPP +V + +
Sbjct: 6648 SCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVN 6706
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARS 242
+ +TWEPP+ D I Y + EL +++ + TVR +
Sbjct: 6707 RFGVSLTWEPPEYD-GGAEITNYVI---ELRDKTSI-----RWDTAMTVRAED------L 6751
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV---PSLPPGALQCNALSSQS 299
T++ + + Y+ V+A N + D PS PP L + + S
Sbjct: 6752 SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSS 6810
Query: 300 VRVSWEPPPMRGRNGILQGY 319
V++ WEPP G + IL GY
Sbjct: 6811 VQLKWEPPLKDGGSPIL-GY 6829
Score = 63.3 bits (147), Expect = 5e-09
Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
Query: 572 VPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINY--KREHGDWEELQVEAGTS 627
V P PP I V +S+ + WS DGGS I GY + K+ G ++ L+ +
Sbjct: 20567 VTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDT 20626
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ L + YQ + A N G G P + A P P ++ +++
Sbjct: 20627 RQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSI 20686
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
T+ W DGG + +V+E R+ + +W VS + + VS L P +Y R++
Sbjct: 20687 TLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 20746
Query: 744 AHNNAG 749
A N AG
Sbjct: 20747 AVNCAG 20752
Score = 62.9 bits (146), Expect = 6e-09
Identities = 93/387 (24%), Positives = 149/387 (38%), Gaps = 41/387 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P+ PKN V ++ + W P + G S IINYIV+ ++ A + W +K +
Sbjct: 15158 PDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD--- 15214
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS--QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L Y RI+AEN G S PS P GPP + RV S +
Sbjct: 15215 LRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSS 15274
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ + W P D I GY V L I + P AG + T
Sbjct: 15275 ISIAWNKPIYD-GGSEITGYMVEI-ALPEEDEWQIVTPP------------AGLKATSYT 15320
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL ++ Y + + A NS ED P L + ++R
Sbjct: 15321 ITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCT 15380
Query: 306 P---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTV 360
P++GR V +A D + D + + + +T L + R+ + +
Sbjct: 15381 LRLFVPIKGR----PAPEVKWA--RDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYIL 15434
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
++G ++A V D P P D+K ++ + ++W PP +L G +
Sbjct: 15435 TVENSSGS--KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPP-----LLDGGSKI 15486
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETS 447
+ I + R E T K + +T H+TS
Sbjct: 15487 KNYIVEKR-ESTRKAYSTVATNCHKTS 15512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 101/427 (23%), Positives = 151/427 (35%), Gaps = 28/427 (6%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQK 120
I + P P V + + W P Y G I Y ++ KE + K
Sbjct: 11891 IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNK 11950
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRV 178
+P VQNL P Y R+ AEN +G EPS P + ++ P GPP + RV
Sbjct: 11951 SAIPER--RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRV 12008
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
+ + + W P D I+GY V + AS G R A
Sbjct: 12009 VDTTKHSITLGWGKPVYD-GGAPIIGYVV-----EMRPKIADASPDEGWK---RCNAAAQ 12059
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
R T++ L ++ Y V A N +++ L P + +A S +
Sbjct: 12060 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI--LEPPEIDLDA-SMR 12116
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDW--YGNEDAVTKQISGLHTTLSGL--RRYT 354
+ + P+R + R AP W G ++ V K L T++ L T
Sbjct: 12117 KLVIVRAGCPIR----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST 12172
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
+ T A D P +D+K + ++ VSW PP + G
Sbjct: 12173 RDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 12232
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV- 473
V + + D + T + T H T+ P + F V+A G G T V
Sbjct: 12233 VTHYIVEKREADRKTWSTVTPEVK-KTSFHVTNLVPGN-EYYFRVTAVNEYGPGVPTDVP 12290
Query: 474 VTVLPSD 480
VL SD
Sbjct: 12291 KPVLASD 12297
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 4/134 (2%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQK 120
+ + +VP P +V ++ ISW +P + G SPI+ Y V+ KE T K
Sbjct: 14754 VANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSK 14813
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
+VPG++ +S L +Y R+IAEN G+S+PS+P + + P + V +
Sbjct: 14814 ALVPGNIFKSS--GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI 14871
Query: 181 KSSTELIVTWEPPQ 194
T + + W P+
Sbjct: 14872 TRHT-VTLKWAKPE 14884
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P +++V D + +SW P G S + +YIV+ +EA ++W + +V
Sbjct: 12202 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV----KK 12257
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPS-GPPQDVRVEAKSSTE 185
TS V NL P Y+ R+ A N G P+ P V ++ + PP+ + V +
Sbjct: 12258 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNS 12317
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W PP RD I GY ++E
Sbjct: 12318 ATLAWLPPLRD-GGAKIDGYITSYRE 12342
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/171 (29%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSR-TIQISWTQPYA-GNSPIINYIVQYKEAPESW 114
TVD + P+ P VI+ + + ISW P G S I NY+V+ EA E
Sbjct: 24213 TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEG- 24271
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSG 171
+ Q V SVT+ + NL Y+ R+ A+N G S+P S V + + E P G
Sbjct: 24272 -AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP-G 24329
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
P + A + +V W+PP D I YY+ +E N + + +
Sbjct: 24330 APGKPTITAVTKDSCVVAWKPPASD-GGAKIRNYYLEKREKKQNKWISVTT 24379
Score = 60.1 bits (139), Expect = 4e-08
Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P K+I+ D + +++W P + G +PI++Y+++ +EA T V+ +
Sbjct: 7982 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR---TYIPVMSGENK 8038
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ---PVQVTTTEEVPSGPPQDVRVEAKSST 184
S +V++L P Y R+ A N++G E + PV + + P PP DV V ++
Sbjct: 8039 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV-IAQDPKQPPDPPVDVEVHNPTAE 8097
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ +TW+PP D I+GY +
Sbjct: 8098 AMTITWKPPLYD-GGSKIMGYII 8119
Score = 60.1 bits (139), Expect = 4e-08
Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 7/151 (4%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVP 124
+++P P +V+ + ++ +SWT P G SPI Y ++ +E W + I
Sbjct: 9099 YRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITK 9158
Query: 125 GSVTSA--SVQNLQPATSYHLRIIAENRLGQSEPSQPV--QVTTTEEVPSGPPQDVRVEA 180
+ +V L Y R +A N G PS+P +V P GPP V+
Sbjct: 9159 VGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQE 211
K+ + + + W+PP +D I GY V QE
Sbjct: 9219 KTKSSISLGWKPPAKD-GGSPIKGYIVEMQE 9248
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Query: 75 NIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQ 133
N+R D ++ + W P G S I NYIV+ +EA ST + V
Sbjct: 14376 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYST---ATTKCHKCTYKVT 14432
Query: 134 NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
L Y R++AEN G EP++ + E PS PP + + + + + + W P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS-PPDSLNIMDITKSTVSLAWPKP 14491
Query: 194 QRDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
+ D I GY + Q S+ I + G
Sbjct: 14492 KHD-GGSKITGYVIEAQRKGSDQWTHITTVKG 14522
Score = 58.4 bits (135), Expect = 1e-07
Identities = 87/331 (26%), Positives = 118/331 (35%), Gaps = 32/331 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P I + + T+ +W P G S IINYIV+ +E W V
Sbjct: 16143 PEGPVVISGVTAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANV----QT 16196
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S V L Y RI+A N+ G EP S+PV VP P+ V +
Sbjct: 16197 LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDA-PKAPEVTTVTKDS 16255
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+IV WE P D ILGY VL G +T G R R T
Sbjct: 16256 MIVVWERPASD-GGSEILGY------------VLEKRDKEGIRWTRCHKRLIGELRLRVT 16302
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVS 303
GL ++ Y V A N+ D PP + ++ SV +S
Sbjct: 16303 --GLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLS 16360
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W P G I QGY V V+ I+ + + L Y+ +CA
Sbjct: 16361 WSKPIYDGGCEI-QGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 16419
Query: 364 TAAGDGVRA---APVYCHTEEDVPSAPADIK 391
AG G A P+ + + P D++
Sbjct: 16420 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLE 16450
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P V D +SWT P + G SPI Y ++ +E W + P +
Sbjct: 11207 PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK---TPIADL 11263
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L +Y R+ AEN G S+P S P++ + P GPP + +++ KS
Sbjct: 11264 KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK-PPGPPINPKLKDKSRET 11322
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W P D ILGY V Q+
Sbjct: 11323 ADLVWTKPLSD-GGSPILGYVVECQK 11347
Score = 57.6 bits (133), Expect = 2e-07
Identities = 75/361 (20%), Positives = 138/361 (38%), Gaps = 39/361 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
E P+N+R+ D ++ +SW QP + G S I YIV+ ++ P+ W + + T
Sbjct: 20272 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNV---TET 20328
Query: 129 SASVQNLQPATSYHLRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ L + Y R+ A N +G S PS+ V T + GP D+ +E +
Sbjct: 20329 QFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYR 20388
Query: 188 VTWEPPQRDLWNGN---ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
R +G + +Y +EL +N+ V + + AS ++ + +
Sbjct: 20389 AGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYEL 20448
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L A+ + VQ + D P P G ++ ++++ + + W
Sbjct: 20449 KLRNAMGSASATIRVQ------------------ILDKPGPPGGPIEFKTVTAEKITLLW 20490
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVTKQISGLHTTLSGLRRYTNYSVTVC 361
PP G G ++T+ V + V++ + T + + + Y V
Sbjct: 20491 RPPADDG------GAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVR 20544
Query: 362 AFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYT 418
A G G + + V P P + ++N + V W P + G + GY
Sbjct: 20545 AVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYF 20604
Query: 419 L 419
L
Sbjct: 20605 L 20605
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 10/187 (5%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGD--WEELQVEAGTSE 628
+P P I V + + + +QW+ + DGG+ I Y+++ KRE W + + +
Sbjct: 22742 IPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD-KREKKSLRWTRVNKDYVVYD 22800
Query: 629 HVLP--NLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTT 683
L +L G YQ +TA N G P + + P P +++ +
Sbjct: 22801 TRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHS 22860
Query: 684 VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
+++ W DGG I+ +V+E +E QW V + F+V L Y R+
Sbjct: 22861 ISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRV 22920
Query: 743 TAHNNAG 749
A N G
Sbjct: 22921 AAVNVKG 22927
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GT 537
++ ARI + R++ E+ SC+ G P P TW G L ++ R V++ T
Sbjct: 26061 TLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST 26120
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
IS Q++D GNY+ VEN G+ E +T+ ++
Sbjct: 26121 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P N+ DQ ++Q+ W P G SPI+ YI++ +E ++W K +VP
Sbjct: 6795 PSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMK-LVPE-- 6851
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L+ Y R+ AEN+ G S+PS+ + T ++ P D+ K E+I
Sbjct: 6852 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVI 6910
Query: 188 V 188
V
Sbjct: 6911 V 6911
Score = 56.8 bits (131), Expect = 4e-07
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP+ P ++D + ++ ++WT P G SPI Y +++KE K P +
Sbjct: 13678 VPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANK--TPIRM 13735
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEV-PSGPPQDVRVEAKSSTE 185
V L Y R++A N G +PS P + V + + P G P+ + + S T
Sbjct: 13736 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT- 13794
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
+ W P+ D + GY V ++L S S
Sbjct: 13795 --LIWTEPKYD-GGHKLTGYIVEKRDLPSKS 13822
Score = 56.8 bits (131), Expect = 4e-07
Identities = 117/551 (21%), Positives = 203/551 (36%), Gaps = 57/551 (10%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+VQ A Y +++ N G + V++ + P+GP + +EA +++W
Sbjct: 24193 NVQRKTHAGKYKVQL--SNVFGTVDAILDVEIQDKPDKPTGP---IVIEALLKNSAVISW 24247
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT--LSG 248
+PP D G+ + YV V GA + + +A S TT +
Sbjct: 24248 KPPADD--GGSWITNYV----------VEKCEAKEGAEWQL-----VSSAISVTTCRIVN 24290
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEP 306
L ++A Y V A N+ ++ P PG A++ S V+W+P
Sbjct: 24291 LTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKP 24350
Query: 307 PPMRGRNGILQGY-RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G I Y W T++I ++ L Y V
Sbjct: 24351 PASDGGAKIRNYYLEKREKKQNKWIS---VTTEEIRETVFSVKNLIEGLEYEFRVKCENL 24407
Query: 366 AGDGVRAAPVYCHT-EEDVPSAPADIKAAVSSRN-----KILVSWLPPSSPNGVLVGYTL 419
G+ + T + DVP K + + N + P ++ Y
Sbjct: 24408 GGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQ 24467
Query: 420 YMSVIEDGRE------EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+I DG + +G + +++ S + + RAT+Q S G A+
Sbjct: 24468 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQ---GGSV---SGTASLE 24521
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
V V +P + + E +S+ G P P TW +++ V
Sbjct: 24522 VEVPAKIHLPKTLEGMGA-VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 24580
Query: 534 SDGTLTISM----TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADS 588
+ T + + D+G Y +N G D+ T ++V P PP + V D DS
Sbjct: 24581 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDS 24640
Query: 589 LHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITA 646
++L W++ DGGS I Y++ + W + +A + + + NL+ T YQ + A
Sbjct: 24641 VNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIA 24699
Query: 647 FNRIGTGLPCD 657
N+ G P +
Sbjct: 24700 ENKFGLSKPSE 24710
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Query: 69 VPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEA-PESWPSTPQKVIVPG 125
VP P I ++D + ISW P G SP+INYIV+ ++ ++W V+ G
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW-----GVVSSG 11160
Query: 126 -SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSS 183
S T + +LQ Y R+ AEN++G P + P PP V +
Sbjct: 11161 SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITE 11220
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
V+W P+ D I GYY+ +E+
Sbjct: 11221 NAATVSWTLPKSD-GGSPITGYYMERREV 11248
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP PK+++V D + ++SW P G I Y+++ + ++W KV
Sbjct: 9414 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWT----KVNPDCG 9469
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSST 184
T+ V +L Y R+ AENR G P + +Q TT + P PP +++ +
Sbjct: 9470 STTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKN 9529
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ ++W+PP+ D G+ + +Y+
Sbjct: 9530 TVHLSWKPPKND--GGSPVTHYI 9550
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
Query: 573 PPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVL 631
PP P +V D ++S+ ++W++ D GSPILGY + KRE +V +
Sbjct: 8405 PPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLE-KREVNSTHWSRVNKSLLNALK 8463
Query: 632 PN---LWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
N L G Y + A N G G P D A+ + P P T +TT
Sbjct: 8464 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIEL 8523
Query: 686 VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W +GG I+ + ++ + + +W + + R ++V + A Y+LR++A
Sbjct: 8524 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM-IKVRQYTVKEIREGADYKLRVSAV 8582
Query: 746 NNAG 749
N AG
Sbjct: 8583 NAAG 8586
Score = 54.8 bits (126), Expect = 2e-06
Identities = 75/309 (24%), Positives = 118/309 (38%), Gaps = 35/309 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P + V + S +SW P G + I +YIVQ +E +W + +V V
Sbjct: 15061 PEGP--LAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEV----QV 15114
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R++A N+ G EP S+PV + P PP++ V +
Sbjct: 15115 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDPPKNPEVTTITKDS 15173
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W P D I+ Y V ++ +G +T+ R
Sbjct: 15174 MVVCWGHPDSD-GGSEIINYIVERRD---------KAGQRWIKCNKKTLTDL-----RYK 15218
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
+SGL + Y + A N+ D PPG + S S+ ++
Sbjct: 15219 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIA 15278
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT---TLSGLRRYTNYSVTV 360
W P G + I GY V A + +E + +GL T++GL Y + +
Sbjct: 15279 WNKPIYDGGSEI-TGYMVEIALPEE---DEWQIVTPPAGLKATSYTITGLTENQEYKIRI 15334
Query: 361 CAFTAAGDG 369
A + G G
Sbjct: 15335 YAMNSEGLG 15343
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 5/149 (3%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIV 123
L + P P V + +I + W +P + G S ++ Y ++ K+ K+++
Sbjct: 20168 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 20227
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
T V + Y R+ AEN G +PS P + + PP++VR+ S
Sbjct: 20228 --RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDA-CEPPRNVRITDISK 20284
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
+ ++W+ P D I GY V ++L
Sbjct: 20285 NSVSLSWQQPAFD-GGSKITGYIVERRDL 20312
Score = 53.2 bits (122), Expect = 5e-06
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 6/140 (4%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ P +++V + ++ I+W P G +P+ NYIV+ +EA T V
Sbjct: 23038 YDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKT---VTTKC 23094
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T + L T Y+ R++ EN G EP + EVP P + V+ ST
Sbjct: 23095 SKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST- 23153
Query: 186 LIVTWEPPQRDLWNGNILGY 205
+ + WE P D + GY
Sbjct: 23154 VTLAWEKPLYD-GGSRLTGY 23172
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N +V D ++ ++W++P Y G +P+ Y+V+ KEA + W + + G
Sbjct: 18506 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK- 18564
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQ 174
+V L+ T Y+ RI A N G EP+ P V E + PP+
Sbjct: 18565 -QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIE--PPE 18609
Score = 52.4 bits (120), Expect = 9e-06
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWP--STPQKVIVPG 125
P P +V D ++ +SW +P Y G SPII Y+V+ K A ++W + PQ +
Sbjct: 13092 PAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL---- 13147
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V L T Y R+ A N++G S+PS
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 70 PEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
P +P I+ + + + + W P G S I NYI++ +++ + W + V
Sbjct: 13579 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV----Q 13634
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSE--PSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T+ V L Y R+ AEN+ G E S+P+ +VP PP V+ + +
Sbjct: 13635 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 13694
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNS 214
+ +TW P++ I GY++ F+E NS
Sbjct: 13695 -VSLTWTDPKK-TGGSPITGYHLEFKERNS 13722
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 11/152 (7%)
Query: 67 HQVPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIV 123
H +P P I+ + S + SW P G PI NY+V+ ++ + W VI
Sbjct: 14659 HDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR 14718
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENR--LGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T+ L Y R+ A+NR +G S + +VP GPP +V A
Sbjct: 14719 ----TTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP-GPPGTPQVTAV 14773
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELN 213
+ + ++W P D ILGY+V +E N
Sbjct: 14774 TKDSMTISWHEPLSD-GGSPILGYHVERKERN 14804
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQ 119
+ + + VP+ P + +I ++W +P + G S I YI++ +E + W
Sbjct: 21647 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 21706
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVR 177
K P S T V L Y ++AEN G S ++ E P GPP V+
Sbjct: 21707 KR--PISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 21764
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
V S T + + W P D I+GY +
Sbjct: 21765 VTDTSKTTVSLEWSKPVFD-GGMEIIGYII 21793
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P + ++ ++ + W +P G I+ Y V+Y+++ +S W + ++ I
Sbjct: 23934 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQF 23993
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T + L AT Y R+ AEN G S P + T ++ SG +R E K T
Sbjct: 23994 T---IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVT 24046
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
Q P+ P ++ V + + + I+W P Y G S I+ YI++ + E W + +VP
Sbjct: 8081 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEH-LVP- 8138
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR--VEAKSS 183
+ + + + L+ Y R+ AEN G SEPS+ T + P +R +E K
Sbjct: 8139 -ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRG 8197
Query: 184 TEL 186
E+
Sbjct: 8198 DEI 8200
Score = 49.6 bits (113), Expect = 6e-05
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T V N+ S + EN G V+V T GPPQD++V+ + T
Sbjct: 15415 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQDLKVKEVTKTS 15470
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP D I Y V +E + +A+ S+ V
Sbjct: 15471 VTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKV-------------- 15515
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
LQ+ +Y V A N + P LPPG + ++ SV +SWE
Sbjct: 15516 -DQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERP-LPPGKITLMDVTRNSVSLSWE 15573
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + ++ A + T++GL + YS V A
Sbjct: 15574 KPEHDGGSRIL-GYIV---EMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNE 15629
Query: 366 AG 367
G
Sbjct: 15630 KG 15631
Score = 49.6 bits (113), Expect = 6e-05
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 10/171 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
++ P P V ++ ++W +P G + I YI++ ++ W +K +
Sbjct: 18402 YKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD 18461
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEV-PSGPPQDVRVEAKS 182
V L SY R+ AEN G EPS+P V + + P GPP + +V S
Sbjct: 18462 ---LRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 18518
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSN--STVLIASGPGGASYTV 231
+ + + W P D + GY V +E ++ +T +G G +TV
Sbjct: 18519 RSSVSLAWSKPIYD-GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568
Score = 49.2 bits (112), Expect = 8e-05
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 9/106 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+N++ D+ + +I ++W P G S I YIV+ + W + + P +
Sbjct: 7090 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE----PVA 7145
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVP 169
T V L+ Y R+ A NR G S+PS+P +Q T+E P
Sbjct: 7146 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 7191
Score = 49.2 bits (112), Expect = 8e-05
Identities = 98/450 (21%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ PK V ++ + W +P + G S I+ Y+++ ++ W +++I G
Sbjct: 16239 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI--GE 16296
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP--VQVTTTEEVPSGPPQDVRVEAKSST 184
+ V L Y R+ AEN G SEPS P Q GPP + +V + +
Sbjct: 16297 LR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 16355
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ ++W P D I GY V +++ + + P G + T VE
Sbjct: 16356 SVFLSWSKPIYD-GGCEIQGYIVEKCDVSVGEWTM-CTPPTGINKTNIEVEKL------- 16406
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L+KH Y + A N +E+ P L ++R
Sbjct: 16407 ----LEKH-EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGG 16461
Query: 305 EP---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVC 361
P++GR V + V + + S L + RY + T+
Sbjct: 16462 SLRLFVPIKGR----PTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 16517
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
++ G ++A V D PS P ++K +++ + ++W PP +L G +
Sbjct: 16518 LENSS--GTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPP-----LLDGGSKIK 16569
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVVTVL 477
+ I + R E T K + T H+ S + ++ F V+A G G + +
Sbjct: 16570 NYIVEKR-EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPI 16628
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNK 507
VP + + VT + ++SLS K
Sbjct: 16629 KVAEVPQPPGKITVDDVT--RNSVSLSWTK 16656
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP+ P I V D ++ +SWT+P + G S II YIV+ + + E W + +
Sbjct: 16632 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP 156
+T NL Y R++A N G+S+P
Sbjct: 16692 VIT-----NLTQGEEYLFRVVAVNEKGRSDP 16717
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 8/143 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
+P PK++ V + ++ + W +P + G S II YIV+ ++ W ++ I
Sbjct: 17321 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD-- 17378
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVTTTEEV-PSGPPQDVRVEAKSST 184
V L Y R+ AEN G EPS V + V GPP + + +
Sbjct: 17379 -LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKN 17437
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ + W P D ILGY V
Sbjct: 17438 SITLAWGKPIYD-GGSEILGYVV 17459
Score = 47.6 bits (108), Expect = 2e-04
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 13/145 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIV-P 124
++P P + + S + ++W P Y G S + + V+ KE W QKV P
Sbjct: 21258 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILW----QKVNTSP 21313
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT--TTEEVPSGPPQDVRVEAKS 182
S L Y R+ AEN G S PS P + T + P G P + V ++
Sbjct: 21314 ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET 21373
Query: 183 STELIVTWEPPQRDLWNGNILGYYV 207
T + W PP RD I+GY +
Sbjct: 21374 IT---LKWNPPLRD-GGSKIVGYSI 21394
Score = 47.2 bits (107), Expect = 3e-04
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWP--STPQKVIVPG 125
P P V D+ +I + W P G SPI YIV+ +E W + P K+I
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLI--- 9264
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
+ V NL+ Y R+ A N G+SEPS TT E+P+ Q+
Sbjct: 9265 TTCECVVPNLKELRKYRFRVKAVNEAGESEPSD-----TTGEIPATDIQE 9309
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 469 EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL 528
E RV + P + S +N+ E+++L C+ G P+P TW +ES++
Sbjct: 882 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 941
Query: 529 RKNVSSDGTLTISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKV 572
++ + M + A DSG +TCS N G + + V+V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPGS 126
VPE P+++ V + T+ ++W P Y G S IINY+++ + E + ++
Sbjct: 10219 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10278
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V+ L+ +Y R+ A N +GQ +PS
Sbjct: 10279 YT---VKGLKEGDTYEYRVSAVNIVGQGKPS 10306
Score = 46.8 bits (106), Expect = 4e-04
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRII 146
I W +P G SP+I Y ++ KE + K I+ T QNL+ Y R+
Sbjct: 16944 IQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD--TQFKAQNLEEGIEYEFRVY 17001
Query: 147 AENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
AEN +G + S+ + + P G P+ + V+ E+ + W P D I G
Sbjct: 17002 AENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYD-GGSMITG 17057
Query: 205 YYVGFQEL 212
Y V ++L
Sbjct: 17058 YIVEKRDL 17065
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 85 TIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T+ + W +P Y G I +YIV+ ++ P W I+ T V L +Y
Sbjct: 14875 TVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFT---VSGLTEDAAYE 14931
Query: 143 LRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
R+IA+N G S PS+P T + P V V+ K + L
Sbjct: 14932 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P +P+ + I + S T+ W++P A G S I Y ++ ++ W ++ I
Sbjct: 20572 PGIPE-VTKITKNSMTVV--WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRD--- 20625
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTE 185
T V L + Y R+ A N GQ S+P + + P GPP +R+ + +
Sbjct: 20626 TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSS 20685
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ + W P D + GY V ++
Sbjct: 20686 ITLGWSKPVYD-GGSAVTGYVVEIRQ 20710
Score = 43.2 bits (97), Expect = 0.005
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 79 IDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
ID TI + W P G S I+ Y ++ ++ E W + S +V L P
Sbjct: 21367 IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SECQYTVTGLSP 21423
Query: 138 ATSYHLRIIAENRLGQ-SEPSQP--VQVTTTEEVP 169
Y RIIA N +G S PSQ + +T E VP
Sbjct: 21424 GDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP 21458
Score = 43.2 bits (97), Expect = 0.005
Identities = 143/721 (19%), Positives = 261/721 (36%), Gaps = 84/721 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE----SWPSTPQKVIVPG 125
+ P V D T+ + W+ P Y G S ++ YI++ K E W ++
Sbjct: 22443 DAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 22502
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLG----QSEPSQPVQVTTTEEVPSGPPQDVR---- 177
T V L +Y R++A+N G SE + PV E P D R
Sbjct: 22503 FFT---VTALSEGDTYEFRVLAKNAAGVISKGSESTGPV-TCRDEYAPPKAELDARLHGD 22558
Query: 178 -VEAKSSTELI----VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
V ++ ++L+ V +P + +W G +EL+ V + A+ ++
Sbjct: 22559 LVTIRAGSDLVLDAAVGGKPEPKIIWT-------KGDKELDLCEKVSLQYTGKRATAVIK 22611
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
+ + + + T+ A +V+V+ +S P P G L
Sbjct: 22612 FCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS------------------PG-PCGKLTV 22652
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
+ ++ + ++W P G I Y V + N V + L ++ L +
Sbjct: 22653 SRVTQEKCTLAWSLPQEDGGAEITH-YIVERRETSRL--NWVIVEGECPTLSYVVTRLIK 22709
Query: 353 YTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y V A G G V + P+ +PS P + + + I++ W P S
Sbjct: 22710 NNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESD 22769
Query: 411 NG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE-- 467
G + Y + + R +K + T TS +QF V+A G
Sbjct: 22770 GGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLM-EGCDYQFRVTAVNAAGNSE 22828
Query: 468 -GEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGV 522
EA+ ++ P + +V K +ISL+ K G M
Sbjct: 22829 PSEASNFISCREPSYTPG--PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 22886
Query: 523 GLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP--- 576
+ R + ++ + T+ + ++ + N+ G E + ++ P +
Sbjct: 22887 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 22946
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEHVLPN 633
P L + D ++ ++ + G VI + ++ D + T + L
Sbjct: 22947 PDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI 23006
Query: 634 LWCGTRY---QLYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKHSQMITLNTTTVTVWL 688
+ RY + I A N+ G +V Y T G P VK K ++ ++ T+T W
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE---VSRDSVTIT-WE 23062
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG + +++E RE + ++ V+ T ++ +SGL Y R+ N
Sbjct: 23063 IPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKT--LYRISGLVEGTMYYFRVLPENIY 23120
Query: 749 G 749
G
Sbjct: 23121 G 23121
Score = 42.3 bits (95), Expect = 0.009
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 13/219 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
+SS V W+PP G I Q Y + + + T G TT++ L
Sbjct: 11811 VSSDRCTVCWDPPEDDGGCEI-QNYILEKCETKRMVWSTYSATVLTPG--TTVTRLIEGN 11867
Query: 355 NYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y V A G G + PV T+ D P P + S+ ++ V W PP G
Sbjct: 11868 EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGG 11927
Query: 413 -VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE-- 469
+ GY L R +K + + + P +QF V A +G GE
Sbjct: 11928 KSITGYFLEKKEKHSTRWVPVNKSAIPERRM--KVQNLLPDHEYQFRVKAENEIGIGEPS 11985
Query: 470 -ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK 507
+R V P T+F +V K +I+L K
Sbjct: 11986 LPSRPVVAKDPIEPPGPPTNF--RVVDTTKHSITLGWGK 12022
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-----KNVSSDG 536
+P +I + +I + ++++C G P P TW+ G + S + +N
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TL I Q D G YT S+ N G D T + ++
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 26924
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
+ P P ++ ++D T+ ++W +P + G S I Y+++ ++ + W V G
Sbjct: 14466 EAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI---TTVKG 14522
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVP 169
V+NL Y +++A N G+S P S+PV V +P
Sbjct: 14523 --LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP 14566
Score = 41.5 bits (93), Expect = 0.016
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENI 558
+LS +G+P P W NGV L + DG +L I T+ D G YTC N
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534
Query: 559 HGR 561
+G+
Sbjct: 3535 YGK 3537
Score = 41.5 bits (93), Expect = 0.016
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
Q P +++V + I W +P++ G S II Y+V + W Q+V+ S
Sbjct: 13385 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW----QRVMKSLS 13440
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
+ S ++L Y R+ AEN G+ PS+ + V ++V + P D++
Sbjct: 13441 L-QYSAKDLTEGKEYTFRVSAENENGEGTPSE-ITVVARDDVVA-PDLDLK 13488
Score = 40.7 bits (91), Expect = 0.028
Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I V + I + WT+P Y G S I YIV+ ++ P+ W ++
Sbjct: 17027 PGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIE--- 17080
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEV 168
T +V L Y R+IA+N G S+PS +T +EV
Sbjct: 17081 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 17123
Score = 39.5 bits (88), Expect = 0.065
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-----SDGTLTISMTQSADSGNYTCS 554
++ C G P P W +GV L + R VS + L ISMT + D+G YT
Sbjct: 1052 SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIV 1111
Query: 555 VENIHG 560
V N HG
Sbjct: 1112 VRNKHG 1117
Score = 39.5 bits (88), Expect = 0.065
Identities = 41/192 (21%), Positives = 77/192 (40%), Gaps = 8/192 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P G L+ ++++ ++W PP G I Y + + + V+ ++
Sbjct: 18303 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANI-SHYIIEKRETSRLSWTQ--VSTEV 18359
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
L+ ++ L Y V A G G + + PV P P+ + + +++
Sbjct: 18360 QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKD 18419
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
++V+W P G + GY L E R +K+ L+ L + +++F
Sbjct: 18420 SMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL--RVTGLTEGHSYEF 18477
Query: 458 WVSASTRLGEGE 469
V+A G GE
Sbjct: 18478 RVAAENAAGVGE 18489
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
P S P +T V+ + G P P WT +G + + +S D
Sbjct: 26350 PISSKPVIVTGLQDTTVSS-DSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG 26408
Query: 538 ---LTISMTQSADSGNYTCSVENIHG 560
L I T ++DSG YTC+V+N G
Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAG 26434
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 508 VGVPAPATTWTMNGVGLES----TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE 563
VG PAP TW L + T+ N + GT ++ Q DSG Y C EN+ G E
Sbjct: 3599 VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG--E 3656
Query: 564 VTYTVEVKV 572
T E+ V
Sbjct: 3657 STCAAELLV 3665
Score = 37.5 bits (83), Expect = 0.26
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSV 555
+N+ +C G P+P W N + + + ++S +L I +DSG YT
Sbjct: 26652 QNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 26711
Query: 556 ENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS 594
+N G+ T ++ V + P VV + LQ S
Sbjct: 26712 KNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGS 26750
Score = 36.3 bits (80), Expect = 0.61
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP +++ + D ++ +SWT+P + G S I Y+V+ K + ++W
Sbjct: 20964 EVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG-----IS 21018
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE 166
V L+ + R+ A+N G S+P +T E
Sbjct: 21019 KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE 21059
Score = 35.9 bits (79), Expect = 0.80
Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 15/151 (9%)
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD-SVPARI 486
+E+GT ++ P+T P + ++ V A R G + ++TV + V
Sbjct: 1462 KEDGTQSLIIVPAT---------PSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMF 1512
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTIS 541
+N+ + + G P P W N + + +GT L I
Sbjct: 1513 VEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
T S DS YT + N GRD V V+V
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 35.9 bits (79), Expect = 0.80
Identities = 27/141 (19%), Positives = 58/141 (41%), Gaps = 7/141 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP +++ + + ++W+ P G S I +I++ K+A P +
Sbjct: 8699 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQP----IETER 8754
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTEL 186
+ + L Y R+IA+N+ G P + + + + P P+ + ++ + +
Sbjct: 8755 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTI 8814
Query: 187 IVTWEPPQRDLWNGNILGYYV 207
+ W+ P R I GY +
Sbjct: 8815 TLDWKEP-RSNGGSPIQGYII 8834
Score = 35.5 bits (78), Expect = 1.1
Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 14/228 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P G + + ++ +SV + WEPP G + + Y + + E V+ +
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV-TNYILLKRETSTAVWTE--VSATV 20127
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ + L Y + A G D + +A V P P+ +R
Sbjct: 20128 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 20187
Query: 399 KILVSWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
I V W P S G +VGY L M + +K ++ T + + ++F
Sbjct: 20188 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI--RTTHFKVTTISAGLIYEF 20245
Query: 458 WVSASTRLGEGEATR-VVTVLPSDSVP----ARITSFSRNIVT-PWKE 499
V A G G+ + VL D+ RIT S+N V+ W++
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQ 20293
Score = 35.5 bits (78), Expect = 1.1
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P + G + I NY ++ +E ++ W S + I T SV+NL Y R+
Sbjct: 24346 VAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI---RETVFSVKNLIEGLEYEFRV 24402
Query: 146 IAENRLGQSEPSQPVQ-VTTTEEVPSGPP 173
EN G+SE S+ + +T +VP P
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPIQAP 24431
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT--LTISMTQSADSGNYTCSVE 556
E C G P P W +NG + + R V DG L I +S D+G + E
Sbjct: 1810 ETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAE 1869
Query: 557 NIHGRDEVTYTVEVK 571
N G E +E++
Sbjct: 1870 NPEGVIEHKVKLEIQ 1884
Score = 33.9 bits (74), Expect = 3.2
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVS---SDGT--LTISMTQSADSGNYTCSVENIHGRDE 563
G P P +W +G + ++ V SDG LTI A+SG Y+ N G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 564 VTYTVEVKVPPQPP 577
T + VK PP
Sbjct: 91 STAELLVKAETAPP 104
Score = 33.9 bits (74), Expect = 3.2
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVS-SDGTLTI 540
A I +FS + + + L N G A W +NGV L ++ R VS SD TLTI
Sbjct: 26542 AEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTI 26599
Query: 541 SMTQSADSGNYTC 553
D G TC
Sbjct: 26600 KQASHRDEGILTC 26612
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 508 VGVPAPATTWTMNGVGLESTLR-KNVSSDG--TLTISMTQSADSGNYTCSVENIHGRDEV 564
+G P W +G LE+ R + ++ G +L + S DSG TC N +G D
Sbjct: 1683 IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1742
Query: 565 TYTVEVK 571
+ T+ VK
Sbjct: 1743 SATLIVK 1749
Score = 33.5 bits (73), Expect = 4.3
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+L I TQ D G YTC N +G T T+ V VP
Sbjct: 4393 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 32.7 bits (71), Expect = 7.5
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
D P RIT R+ P +N N P W NGV L ES+ ++ G L
Sbjct: 25874 DHAP-RITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 25932
Query: 539 TISM--TQSADSGNYTCSVENIHGRDEVTYTVEV 570
T+ + + DSG Y N G T++V
Sbjct: 25933 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 145 bits (351), Expect = 9e-34
Identities = 113/419 (26%), Positives = 182/419 (43%), Gaps = 30/419 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N+R + +I +SW+ P II Y + ++E + P T
Sbjct: 512 VPGQPMNLRAEARSETSITLSWSPPR--QESIIKYELLFREGDHG--REVGRTFDP--TT 565
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V++L+P T Y R+ A + G + V+ T + PS PPQDV+ + ST ++V
Sbjct: 566 SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILV 625
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP + NG ++GY V ++ L S + V G ++ L
Sbjct: 626 SWRPPPPETHNGALVGYSVRYRPLGSEDP------------EPKEVNGIPPTTTQILLEA 673
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + A+ EDVPS PP ++ AL++ ++RV W P
Sbjct: 674 LEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPA 733
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI---SGLHTTLSGLRRYTNYSVTVCAFTA 365
++G ++GY+V Y + K + ++ L+ T YS+TV A+T
Sbjct: 734 PGRQHGQIRGYQVHYVRMERREARGRRSIKDVMLADAQEMVITNLQPETAYSITVAAYTM 793
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS-SPNGVLVGYTLYMSVI 424
GDG R+ P T+ V P + + +L W PP+ + ++GY L
Sbjct: 794 KGDGARSKPKVVVTKGAVLGRPT-LSVQQTPEGSLLARWEPPAGTAEDQVLGYRL----- 847
Query: 425 EDGREEGTHKRMLS--PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
+ GRE+ T L PS + S AT+ F ++A + G GE V +P D+
Sbjct: 848 QFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSPGGLGEEAAEVLSIPEDT 906
Score = 120 bits (289), Expect = 3e-26
Identities = 162/647 (25%), Positives = 261/647 (40%), Gaps = 75/647 (11%)
Query: 134 NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
+++ + +YH +A + LG E + V + + P P V ++T + +TW
Sbjct: 289 DVKDSANYH-PCVAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW--- 340
Query: 194 QRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHA 253
D N + + YYV E S S GP Y ++ E T +R ++ GL ++
Sbjct: 341 --DSGNPDPVSYYV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNS 384
Query: 254 AYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRN 313
Y + V A NS E P+ PP +Q LS+ ++ V WE P N
Sbjct: 385 EYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVEP--N 442
Query: 314 GILQGYRVTYA-----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G+++GYRV Y PV +W N D L TT+ L Y+V V AFT+ G
Sbjct: 443 GLIRGYRVYYTMEPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVG 496
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDG 427
DG + P+ T++ VP P +++A S I +SW PP + ++ Y L + G
Sbjct: 497 DGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHG 554
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV---TVLPSDSVPA 484
RE G R P+T S+ P + F ++A + G G T VV T+ S P
Sbjct: 555 REVG---RTFDPTT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPP 610
Query: 485 R----ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLT 539
+ ++ S I+ W+ + N V + +G E K V+ T T
Sbjct: 611 QDVKCVSVRSTAILVSWRPPPPETHNGALV---GYSVRYRPLGSEDPEPKEVNGIPPTTT 667
Query: 540 ISMTQSADSGNYTCSVENIHGR-------DEVTYTVEVKVPPQPPILAVVDSY-ADSLHL 591
+ ++ + H V + VP PP ++ A ++ +
Sbjct: 668 QILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRV 727
Query: 592 QWSDQGDG--GSPILGYVINY----KREHGDWEELQ--VEAGTSEHVLPNLWCGTRYQLY 643
W G I GY ++Y +RE ++ + A E V+ NL T Y +
Sbjct: 728 LWRSPAPGRQHGQIRGYQVHYVRMERREARGRRSIKDVMLADAQEMVITNLQPETAYSIT 787
Query: 644 ITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
+ A+ G G TKG V +P S T + + W G +L + +
Sbjct: 788 VAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRL 847
Query: 704 EY-REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ RE S P L + +E ++ SG+ A Y R+ A + G
Sbjct: 848 QFGREDSTP---LATLEFPPSEDRYTASGVHKGATYVFRLAARSPGG 891
Score = 116 bits (279), Expect = 5e-25
Identities = 110/420 (26%), Positives = 176/420 (41%), Gaps = 33/420 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 319 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 372
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ PP++V+ S+T +I
Sbjct: 373 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMI 432
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 433 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 477
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 478 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 536
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R + Y + + +G E T + + + L+ T Y+ + A + G
Sbjct: 537 ----RQESIIKYELLFREGD--HGREVGRTFDPTTSY-VVEDLKPNTEYAFRLAARSPQG 589
Query: 368 DGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWL--PPSSPNGVLVGYTLYMSVI 424
G V T + PSA P D+K ILVSW PP + NG LVGY++ +
Sbjct: 590 LGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL 649
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
E + P+T ++ A T +G G + V V + VP+
Sbjct: 650 GSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPS 709
Score = 114 bits (274), Expect = 2e-24
Identities = 105/409 (25%), Positives = 166/409 (40%), Gaps = 33/409 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P++++ + +S I +SW P N ++ Y V+Y+ P + +P + T
Sbjct: 610 PQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQI 669
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L+ T Y + +A +G S PV V T E+VPS PP+ V EA ++T + V W
Sbjct: 670 LLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLW 729
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P +G I GY V + + A G +++ V A ++ LQ
Sbjct: 730 RSPAPGRQHGQIRGYQVHYVRMERRE----ARG----RRSIKDVMLADA--QEMVITNLQ 779
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
AY++ V AY + V P L S+ WEPP
Sbjct: 780 PETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP--TLSVQQTPEGSLLARWEPPAGT 837
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDA---VTKQI--SGLHTTLSGLRRYTNYSVTVCAFTA 365
+ +L GYR+ +G ED+ T + S T SG+ + Y + A +
Sbjct: 838 AEDQVL-GYRLQ-------FGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSP 889
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAA-VSSRNKILVSWLP--PSSPNGVLVGYTLYM- 421
G G AA V E+ P ++AA +S +L+ WLP P+ NG +V YT+ +
Sbjct: 890 GGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVR 949
Query: 422 --SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
+ RE LS + + P + V A TR G G
Sbjct: 950 EAGALGPARETELPAGRLSRARRTLTLQGLKPDTAYDLQVRAHTRRGPG 998
Score = 74.1 bits (174), Expect = 2e-12
Identities = 66/255 (25%), Positives = 111/255 (43%), Gaps = 11/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY-TCSVENI 558
N++++C VG P P W G E ++ G + +T DS NY C +
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYHPCVAMSS 304
Query: 559 HGRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 305 LGVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGNP-DPVSYYVIEYKSKSQDG 362
Query: 618 E-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
+++ + T+ + + L + Y+++++A N IG G P + V T P + P++ Q
Sbjct: 363 PYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQ 422
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 423 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLE 481
Query: 735 AAHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 482 DETYTVRVLAFTSVG 496
Score = 73.7 bits (173), Expect = 3e-12
Identities = 86/348 (24%), Positives = 129/348 (37%), Gaps = 28/348 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQY--KEAPESWPSTPQKVIVPGSVT 128
P+ + + I++ W P G + I Y V Y E E+ K ++
Sbjct: 712 PRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMERREARGRRSIKDVMLADAQ 771
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+ NLQP T+Y + + A G S+P V T V P V+ + S L+
Sbjct: 772 EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGS--LLA 829
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
WEPP +LGY + F +S + P + R T SG
Sbjct: 830 RWEPPAGTA-EDQVLGYRLQFGREDSTPLATLEFPP---------------SEDRYTASG 873
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA-LSSQSVRVSWEPP 307
+ K A Y + A S ED P P L+ S+ +V + W PP
Sbjct: 874 VHKGATYVFRLAA-RSPGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPP 932
Query: 308 PMRGRNGILQGYRVTY--APVTDWYGNEDAVTKQISGLHTTLS--GLRRYTNYSVTVCAF 363
RNG + Y V A + ++S TL+ GL+ T Y + V A
Sbjct: 933 VPAERNGAIVKYTVAVREAGALGPARETELPAGRLSRARRTLTLQGLKPDTAYDLQVRAH 992
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
T G G + PV T +P + K + + +L+SW P + N
Sbjct: 993 TRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYN 1040
Score = 52.8 bits (121), Expect = 7e-06
Identities = 73/310 (23%), Positives = 125/310 (40%), Gaps = 22/310 (7%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + + A +GE +TVL D +P+ + V ++ C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 508 VGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG---R 561
G P P TW + + ++ S R G L I ++ D G Y C N G
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 562 DEVTYTVEV-KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL 620
V V +V P+ IL + ++ + GSP + YV + E
Sbjct: 219 SPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVA-VGSP-MPYVKWMQGAEDLTPED 276
Query: 621 QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ G + L ++ Y + A + +G + V T ++P P + M+T N
Sbjct: 277 DMPVGRNVLELTDVKDSANYHPCV-AMSSLGV---IEAVAQITVKSLPKAP-GTPMVTEN 331
Query: 681 T-TTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
T T++T+ DS + Y+VIEY+ SQ + + T +S+ GL+P + Y+
Sbjct: 332 TATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTTR--YSIGGLSPNSEYE 387
Query: 740 LRITAHNNAG 749
+ ++A N+ G
Sbjct: 388 IWVSAVNSIG 397
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 144 bits (350), Expect = 1e-33
Identities = 158/698 (22%), Positives = 265/698 (37%), Gaps = 44/698 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P RV+D +I ++WT+P Y G + I+ Y+++ +E + W +
Sbjct: 22845 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRN-- 22902
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +L+ Y R+ A N G SE S+ + E P ++ + K + +
Sbjct: 22903 TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIR 22962
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G L V ++ +I G R + + S +
Sbjct: 22963 A-----------GASLRLMVS---VSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ ++ A ++A N + D P P +++ +S SV ++WE P
Sbjct: 23009 KVNRYDAGKYTIEAENQ---SGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIP 23064
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
+ G + Y V VT + S +SGL T + V G
Sbjct: 23065 TIDG-GAPINNYIVEKREAA--MRAFKTVTTKCSKTLYRISGLVEGTMHYFRVLPENIYG 23121
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIED 426
G +VP PA ++ +++ + ++W P G L GY L +
Sbjct: 23122 IGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL--EACKA 23179
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR- 485
G E L P+ L H + + F + A G E VT + +
Sbjct: 23180 GTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP 23239
Query: 486 ----ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTL 538
T + I P + L G P PA +W G L + R V + L
Sbjct: 23240 TIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKL 23299
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS-D 595
TI T D+G YT ++N+ G T V + P PP + + + A S+ + W
Sbjct: 23300 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP 23359
Query: 596 QGDGGSPILGYVINYKREH-GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG- 653
+ DGG+P+ GYV+ + H W + S L G Y + A NR G G
Sbjct: 23360 ELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 23419
Query: 654 -LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP 711
L +++ + +P P+ Q+ ++ +T+ W DGG + +++E +E+
Sbjct: 23420 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD 23479
Query: 712 QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V N V T + +GLT Y+ R+TA N G
Sbjct: 23480 RWVRV-NKVPVTMTRYRSTGLTEGLEYEHRVTAINARG 23516
Score = 135 bits (327), Expect = 7e-31
Identities = 160/666 (24%), Positives = 271/666 (40%), Gaps = 61/666 (9%)
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
E+ P + + + TS + + +I+ +N+ G++E ++V +VP G
Sbjct: 6539 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI---DVP-G 6594
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
P +++ V E+ + WE P D I+GY V +++ + VL +TV
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTD-GGSKIIGYVVERRDIKRKTWVLATDRAESCEFTV 6653
Query: 232 RTVEGAGTARSRTTLSGLQKHAA-YAVVVQAYN---SRXXXXXXXXXXXXXMEDVPSLPP 287
+GLQK Y V A N + DVP PP
Sbjct: 6654 ---------------TGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPG-PP 6697
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHT 345
+ ++ V ++WEPP G + Y + T W + A+T + L
Sbjct: 6698 LNVTITDVNRFGVSLTWEPPEYDG-GAEITNYVIELRDKTSIRW---DTAMTVRAEDLSA 6753
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV-RAAPVYCHTEEDV--PSAPADIKAAVSSRNKILV 402
T++ + YS V A G G AA + + + PS P ++ ++ +++ + +
Sbjct: 6754 TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQL 6813
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
W PP G ++GY + E+G++ M L+++ + + + VSA
Sbjct: 6814 KWEPPLKDGGSPILGYIIERC--EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSA 6871
Query: 462 STRLGEGEATRVVTVLPSDSV---PAR-ITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ G + + ++ L +D P +++F + I++ G P P TW
Sbjct: 6872 ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATW 6931
Query: 518 TMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV-- 572
LE+ R K +S+ L IS ++ +D G YT +EN ++ ++V V
Sbjct: 6932 CFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN--RVKTISGEIDVNVIA 6989
Query: 573 -PPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSE 628
P P L D DS+HL W DGGSP+ GYV+ KRE W ++ E
Sbjct: 6990 RPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE-KREVSRKTWTKVMDFVTDLE 7048
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQM--ITLNTTT 683
+P+L G Y + A N+ G G P + V+ T TVP P++ + T N+
Sbjct: 7049 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 7108
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
+T W DGG I +++E +W V T+ V+GL Y R+
Sbjct: 7109 LT-WDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETK--MEVTGLEEGKWYAYRVK 7165
Query: 744 AHNNAG 749
N G
Sbjct: 7166 TLNRQG 7171
Score = 134 bits (323), Expect = 2e-30
Identities = 167/663 (25%), Positives = 267/663 (40%), Gaps = 51/663 (7%)
Query: 111 PESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
P + + K++V + T Q+ + T + I A N LG + + V P
Sbjct: 9666 PVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT-ITAVNNLGTASKEMRLNVLGRPGPPV 9724
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
GP ++ E+ S+ ++ ++W PP+ D I Y + +E N + V ++S P +YT
Sbjct: 9725 GP---IKFESVSADQMTLSWFPPKDD-GGSKITNYVIEKREANRKTWVHVSSEPKECTYT 9780
Query: 231 V-RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA 289
+ + +EG + ++ Q + VP P
Sbjct: 9781 IPKLLEG--------------HEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKP 9826
Query: 290 LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISGLHTT 346
++++ S+ V+WE P G + + GY + T W N D + G+
Sbjct: 9827 T-VSSVTRNSMTVNWEEPEYDGGSPVT-GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYK 9884
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSW 404
++GL ++Y V A AAG G + P T D P P K +++ + W
Sbjct: 9885 VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEW 9944
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
PP G V GY + E+G+EE + + A ++F VSA
Sbjct: 9945 SPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVN 10002
Query: 464 RLGEGEATRVVTVLPSD----SVPARITSFSRN-IVTPWKENISLSCNKVGVPAPATTWT 518
G GE V V+ S ++ + R+ IV I + G P P TW
Sbjct: 10003 IAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWN 10062
Query: 519 MNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP 576
MN L E+T+ S ++ I Q + G Y+ +N G + T V+V P P
Sbjct: 10063 MNERTLPQEATIETTAIS-SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGP 10121
Query: 577 ---PILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVL 631
P LA + +S L W S + DGGSPI YVI + + W + +
Sbjct: 10122 VGTPFLA-HNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATV 10180
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQM--ITLNTTTVTV 686
L G Y I A N IG G + A TVP +P+ ++ +T NT T+T
Sbjct: 10181 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT- 10239
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W DGG I+ +V+E R + ++ V+N R ++V GL Y+ R++A N
Sbjct: 10240 WNPPKYDGGSEIINYVLESRLIGTEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVN 10298
Query: 747 NAG 749
G
Sbjct: 10299 IVG 10301
Score = 132 bits (318), Expect = 9e-30
Identities = 161/707 (22%), Positives = 288/707 (40%), Gaps = 64/707 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
+P P +++D TI I+W +P + G +PI Y V+YK++ ++ W ++ Q +
Sbjct: 19586 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL----R 19641
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T ++ L Y R+ + N++G S+PS +E P D+ E + + L
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKT--L 19699
Query: 187 IV------TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
IV T P R N+L + + + + + S T+ +
Sbjct: 19700 IVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSG 19756
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ T+ + A+ +VV+ D P PP + ++ +S
Sbjct: 19757 KYTLTIQNVLSAASLTLVVKVL------------------DTPG-PPTNITVQDVTKESA 19797
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
+SW+ P G ++ Y + + W +VT + L ++ L+ Y
Sbjct: 19798 VLSWDVPENDG-GAPVKNYHIEKREASKKAWV----SVTNNCNRLSYKVTNLQEGAIYYF 19852
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V G G+ A + PS P + S++ + ++WL P G + +
Sbjct: 19853 RVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHY 19912
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VL 477
+ + +E G++ K ++ ST H S + + F V A + G + ++ VL
Sbjct: 19913 V-VEALEKGQKNWV-KCAVAKST-HHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 19969
Query: 478 PSDSV-PARIT--SF-SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+ + P I +F S + N+ + G P P T + +GV L++T+R N
Sbjct: 19970 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 20029
Query: 534 SDG-TLTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADS 588
LTI++ +S AD+G Y + N G + + V P PP VV D +S
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 20089
Query: 589 LHLQWS-DQGDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
+ L+W + DGGS + Y++ KRE W E+ + + L G YQ I
Sbjct: 20090 VTLKWEPPKYDGGSQVTNYIL-LKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIK 20148
Query: 646 AFNRIGTGLPCDIVHAYTK--GTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFV 702
A NR G D K T P P + + ++TV W + +GG ++ +
Sbjct: 20149 AENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYH 20208
Query: 703 IEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E ++ + W+ + V T F V+ ++ Y+ R+ A N AG
Sbjct: 20209 LEMKDRNSILWQKANKLVIRTTH-FKVTTISAGLIYEFRVYAENAAG 20254
Score = 130 bits (313), Expect = 4e-29
Identities = 179/723 (24%), Positives = 285/723 (39%), Gaps = 63/723 (8%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES- 113
+TV + I L P P IR+ + +I ISW P Y G I NYIV+ KE +
Sbjct: 18979 ITVPITIIVLDRPGPPGP--IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT 19036
Query: 114 WPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGP 172
W Q V + TS + L + Y R+ AENR G+S S+ V P GP
Sbjct: 19037 WHIVSQAV----ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGP 19092
Query: 173 PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
P +V + + ++VTW+ P D ++GY++ ++E S++L + A+ +
Sbjct: 19093 PGTPKVVHATKSTMLVTWQVPVND-GGSRVIGYHLEYKE---RSSILWSK----ANKIL- 19143
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
A ++ +SGL + Y V A N D P PPG +
Sbjct: 19144 ------IADTQVKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD-PCDPPGQPEV 19196
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
++ +SV + W P G + GY V + D + T I + ++ L
Sbjct: 19197 TNITRKSVSLKWSKPHYDG-GAKITGYIVERRELPDGRWLKCNYTN-IQETYFEVTELTE 19254
Query: 353 YTNYSVTVCAFTAAGD----GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
Y V A AA P+ + + P D+K R+ I+V
Sbjct: 19255 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKF----RDVIVVKAGEVL 19310
Query: 409 SPNGVLVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPP---RATHQFWVSASTR 464
N + G L +S +DG E R ST +H R T Q+ ++
Sbjct: 19311 KINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNV 19370
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G VL PA N +T E SLS + A +
Sbjct: 19371 AGTRSVAVNCKVLDKPGPPAGPLEI--NGLTA--EKCSLSWGRPQEDGGADIDYYHRKKR 19426
Query: 525 ESTLRKNVSSDGTLTIS---MTQSADSGNYTCSVENI--HGRDEVTYTVEVK------VP 573
E++ +G L ++ +T+ Y V + +G E +V +K VP
Sbjct: 19427 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 19486
Query: 574 PQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
P L + +S+ L WS + DGGS I GY+I + ++ W + + V
Sbjct: 19487 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 19546
Query: 632 PN-LWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTVTV- 686
L G Y+ + A N G LP + ++ A +P P +++ TT+T+
Sbjct: 19547 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 19606
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W+ DGG I + +EY++ W+ S++ TE +++SGLT A Y R+ + N
Sbjct: 19607 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE--YTISGLTTGAEYVFRVKSVN 19664
Query: 747 NAG 749
G
Sbjct: 19665 KVG 19667
Score = 128 bits (309), Expect = 1e-28
Identities = 162/706 (22%), Positives = 281/706 (39%), Gaps = 54/706 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P V D +++++WT+P + G + I +Y+++ K + W + V
Sbjct: 7487 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV----PT 7542
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSSTE 185
T + L Y R+ A N+ G+SEPS+P E P PP+ + V +
Sbjct: 7543 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7602
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ W P++D I Y V +++ + + TV+ ++ T
Sbjct: 7603 ADLKWTVPEKD-GGSPITNYIVEKRDVRRKGWQTVDT-------TVKD--------TKCT 7646
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVS 303
++ L + + Y V A N+ +D + P P AL ++ + V +
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 7706
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVC 361
WEPP G I Q Y + + G + +G + ++ + T V
Sbjct: 7707 WEPPKNDGGRPI-QRYVIEKK---ERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVR 7762
Query: 362 AFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGY 417
A AG G + P + ED PS P D+ + R I ++W PP G ++GY
Sbjct: 7763 AENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV---V 474
+ M + + + R + E P + + V A +G E + + V
Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK-EYVLRVRAVNAIGVSEPSEISENV 7881
Query: 475 TVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS 534
D P I + +I+ E +S+ VP P +W +G ++++ R + +
Sbjct: 7882 VAKDPDCKPT-IDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN 7940
Query: 535 D---GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSYADSLH 590
D L + + AD+G YT ++EN G + V+V P P + D S
Sbjct: 7941 DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 8000
Query: 591 LQWS-DQGDGGSPILGYVINYKREHGDWEELQVEAGTSE--HVLPNLWCGTRYQLYITAF 647
L W + DGG+PIL YV+ +RE G + V +G ++ + +L Y + A
Sbjct: 8001 LTWEPPEFDGGTPILHYVLE-RREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8059
Query: 648 NRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVI 703
N++G G ++ V A P P ++ +T+ W DGG I+ ++I
Sbjct: 8060 NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYII 8119
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
E + +W+ N ++ GL YQ R+ A N AG
Sbjct: 8120 EKIAKGEERWKR-CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 8164
Score = 128 bits (309), Expect = 1e-28
Identities = 164/708 (23%), Positives = 278/708 (39%), Gaps = 64/708 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P IR+ D +I + W++P Y G S + Y+V+ ++ E W + K V
Sbjct: 20670 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV--RT 20727
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ------SEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T V NL+P +Y+ R+ A N GQ +EP Q + E+ V AK
Sbjct: 20728 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 20787
Query: 182 SSTELIVT----WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
+ ++ V PP W + + L S++ I + + T+ V
Sbjct: 20788 AGEDVQVLIPFKGRPPPTVTWRKDE-------KNLGSDARYSIENTDSSSLLTIPQVTRN 20840
Query: 238 GTARSRTTL-SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
T + T+ +G+ + + V V+ D P+ LQ +S
Sbjct: 20841 DTGKYILTIENGVGEPKSSTVSVKVL------------------DTPAACQ-KLQVKHVS 20881
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+V + W+PP + G + I+ Y + T V+ + S L L T +
Sbjct: 20882 RGTVTLLWDPPLIDGGSPIIN-YVIEKRDATK--RTWSVVSHKCSSTSFKLIDLSEKTPF 20938
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V A G G +VP+ D+ S++ +++SW P G ++
Sbjct: 20939 FFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVI- 20997
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
T Y+ V G+ E T T E S+ ++ +F V A G + + +
Sbjct: 20998 -TEYV-VERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21055
Query: 477 LPSDSVPARITSFS----RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKN 531
+ + S + N+ L G P P+ +W +G+ L ES +
Sbjct: 21056 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 21115
Query: 532 VSSDGTLTISM--TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYAD 587
++ +T+S+ + G YT ++N R V TV PP P + + AD
Sbjct: 21116 SKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 21175
Query: 588 SLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S+ L W + +GG I Y I KRE +W+ + + +PNL YQ +
Sbjct: 21176 SVILSWDVPEDNGGGEITCYSIE-KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRV 21234
Query: 645 TAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYF 701
A NR G P I+ A + +P P + + + +++ W DGG + F
Sbjct: 21235 RAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGF 21294
Query: 702 VIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E +E + W+ V N+ + R + +GL YQ R+ A N+AG
Sbjct: 21295 HVEKKERNSILWQKV-NTSPISGREYRATGLVEGLDYQFRVYAENSAG 21341
Score = 126 bits (305), Expect = 3e-28
Identities = 157/709 (22%), Positives = 286/709 (40%), Gaps = 69/709 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P ++V D T+ + W++P + G II YI++ K W + V
Sbjct: 21757 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKTDLGDWHKVNAEACVK--- 21813
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +LQ Y R+ A N G+ + + + + P D+ K T ++
Sbjct: 21814 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ-THVV 21872
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G + ++ +Q + + V S P ++ ++R + S T+
Sbjct: 21873 RA----------GASIRLFIAYQGRPTPTAVW--SKPD-SNLSLRADIHTTDSFSTLTVE 21919
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
++ A + N+ + D P PPG + ++ S + W+ P
Sbjct: 21920 NCNRNDAGKYTLTVENN---SGSKSITFTVKVLDTPG-PPGPITFKDVTRGSATLMWDAP 21975
Query: 308 PMRGRNGILQGYRVTYAPVT--DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
+ G + Y V + W + T+QI ++ G+ Y + V+
Sbjct: 21976 LLDG-GARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY--FRVSAVNEYG 22032
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVI 424
G+ TE+ P+ P + +S++ +++WL P G + GY L M
Sbjct: 22033 VGEPYEMPEPIVATEQ--PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM--- 22087
Query: 425 EDGREEGTHKRMLSPST--LSHETSRSPPRATHQFWVSASTRLGEGEA----TRVVTVLP 478
R++G+ + + T L+ R + ++F V A G E + V+ P
Sbjct: 22088 ---RQKGSDLWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP 22144
Query: 479 SDSVPARITSFSRNIVT-----PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
A +T + ++T P+ ++ +S G PAP TW + + L+ T R +++
Sbjct: 22145 QIEPTADLTGITNQLITCKAGSPFTIDVPIS----GRPAPKVTWKLEEMRLKETDRVSIT 22200
Query: 534 SDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADS 588
+ TLT+ + DSG Y ++EN G + TV V P P + V A+S
Sbjct: 22201 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAES 22260
Query: 589 LHLQWSDQGD-GGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
L W + D GG+ I Y++ KRE G W+ + ++ + +L Y ++
Sbjct: 22261 CVLSWGEPKDGGGTEITNYIVE-KRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVS 22319
Query: 646 AFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ NR G P + H + + P +P+ ++ N ++ W + + DGG I+
Sbjct: 22320 SENRFGVSKPLESAPIIAEHPFVPPSAPTRPE-VYHVSANAMSIR-WEEPYHDGGSKIIG 22377
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +E +E + W + N V E + V+GL YQ R A N AG
Sbjct: 22378 YWVEKKERNTILW-VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 22425
Score = 125 bits (302), Expect = 8e-28
Identities = 159/712 (22%), Positives = 283/712 (39%), Gaps = 63/712 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P PK ++ D ++ ++W P G SP+ Y+V+ +E T KV+ +
Sbjct: 6991 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRK---TWTKVMDFVTDL 7047
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+V +L Y ++ A N+ G EP+ +PV ++T VP PP++V+ +++
Sbjct: 7048 EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANS 7106
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP+ D I GY ++ P G+ V G A ++
Sbjct: 7107 IFLTWDPPKND-GGSRIKGY-------------IVERCPRGSDKWVAC--GEPVAETKME 7150
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL++ YA V+ N + D P L L+ +V+ +
Sbjct: 7151 VTGLEEGKWYAYRVKTLNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7210
Query: 306 ---PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVT-KQISGLHT-TLSGLRRYTNYSVTV 360
P + G+ ++T+ + +T + + T T+ +R + +
Sbjct: 7211 IELPATVTGK----PEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII 7266
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
A G RA V D P PA + L++W PP G + T Y
Sbjct: 7267 EAVNVCG---RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNY 7321
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLP 478
+ E HK + + + ++ P + F V+A G GE + +T
Sbjct: 7322 VVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGAGEPVQASPITAKY 7381
Query: 479 SDSVPARITSFSRNIVTPWKENISLS-CNKVGVP-APATTWTMNGVGLEST----LRKNV 532
P T + +T K+ ++L+ C +P T + + + ++ K
Sbjct: 7382 QFDPPGPPTRLEPSDIT--KDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMP 7439
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVV-DSY 585
D T + + + EN+ G + + + E + PP PP V D
Sbjct: 7440 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVG 7499
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLY 643
S+ L W+ + DGG+ I YVI + D W + T++H+LP L G Y
Sbjct: 7500 KTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFR 7559
Query: 644 ITAFNRIG---TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
+ A N+ G P D V K P P+ ++I + T + W DGG I
Sbjct: 7560 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPIT 7619
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+++E R++ + W+ V +V+ T+ +V+ LT + Y R+ A N G +
Sbjct: 7620 NYIVEKRDVRRKGWQTVDTTVKDTK--CTVTPLTEGSLYVFRVAAENAIGQS 7669
Score = 125 bits (302), Expect = 8e-28
Identities = 155/614 (25%), Positives = 250/614 (40%), Gaps = 50/614 (8%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S PV V + P P V+V +S + +TW PP +D G+ + +YV +
Sbjct: 17211 SFPVNVKVLDR-PGPPEGPVQVTGVTSEKCSLTWSPPLQD--GGSDISHYV----VEKRE 17263
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
T +A +TV E + T L ++ + V Y
Sbjct: 17264 TSRLA-------WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMK 17316
Query: 277 XXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNED 334
+P PP +L+ ++ S+ V W P G + I+ GY V + W
Sbjct: 17317 NPFV-LPG-PPKSLEVTNIAKDSMTVCWNRPDSDGGSEII-GYIVEKRDRSGIRWI---K 17370
Query: 335 AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA-APVYCHTEEDV--PSAPADIK 391
++I+ L ++GL Y V A AAG G + A VY + V P P +
Sbjct: 17371 CNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 17430
Query: 392 AAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST----LSHET 446
+++N I ++W P G ++GY V+E + + ++++P T E
Sbjct: 17431 IVDTTKNSITLAWGKPIYDGGSEILGY-----VVEICKADEEEWQIVTPQTGLRVTRFEI 17485
Query: 447 SRSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENI 501
S+ ++ V A ++G GEAT V TV P D + A + + IV +
Sbjct: 17486 SKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSA 17545
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHG 560
+ G P P TW+ ++ + T L+I D+G Y +EN G
Sbjct: 17546 RIHIPFKGRPMPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 17605
Query: 561 RDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGD 616
TV+V P PP LAV + DS L W DGG+ + YVI+ KRE
Sbjct: 17606 SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID-KRESTRKA 17664
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
+ + + + + NL G Y + A N G G+P + V A P P +
Sbjct: 17665 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17724
Query: 677 ITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
++ T+ + +W DGG +L +V+E + +W +V+ S + V V+GL+
Sbjct: 17725 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV--VTGLSSG 17781
Query: 736 AHYQLRITAHNNAG 749
YQ R+ A+N G
Sbjct: 17782 QEYQFRVKAYNEKG 17795
Score = 125 bits (301), Expect = 1e-27
Identities = 125/486 (25%), Positives = 203/486 (41%), Gaps = 30/486 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTK 338
D P PP + +S S V+WEPP + G + I+ Y V A W VT
Sbjct: 13288 DTPG-PPINVTVKEISKDSAYVTWEPPIIDGGSPIIN-YVVQKRDAERKSW----STVTT 13341
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ S + L +Y V A G G P D+K S++
Sbjct: 13342 ECSKTSFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKS 13401
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
+ W P S G ++GY V++ EE +R++ +L + + F
Sbjct: 13402 SCSIGWKKPHSDGGSRIIGY-----VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456
Query: 458 WVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKENIS--LSCNKVGVPAPA 514
VSA GEG + + V D V P ++ KEN + L G PAP+
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13516
Query: 515 TTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
+W L + R +V S TL + Q +D+G YT +++N+ G E T +++V
Sbjct: 13517 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13576
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGT 626
P P + + A+++ L+W+ + DGGS I Y++ KR+ + W
Sbjct: 13577 GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSVNNKWVTCASAVQK 13635
Query: 627 SEHVLPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ + L G Y ++A N+ +G GL + + A VP P ++ + +V
Sbjct: 13636 TTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSV 13695
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W D GG I + +E++E + W+ +N R F V+GLT Y+ R+
Sbjct: 13696 SLTWTDPKKTGGSPITGYHLEFKERNSLLWKR-ANKTPIRMRDFKVTGLTEGLEYEFRVM 13754
Query: 744 AHNNAG 749
A N AG
Sbjct: 13755 AINLAG 13760
Score = 124 bits (299), Expect = 2e-27
Identities = 157/633 (24%), Positives = 243/633 (38%), Gaps = 56/633 (8%)
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
H + N G++ + V V P+GP V+++ ++ + ++W PP+ D G+
Sbjct: 15720 HYVVKLTNSAGEAIETLNVIVLDKPGPPTGP---VKMDEVTADSITLSWGPPKYD--GGS 15774
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ Y+ + S +T I S A AR+ L+ Y + A
Sbjct: 15775 SINNYIVEKRDTSTTTWQIVS--------------ATVARTTIKACRLKTGCEYQFRIAA 15820
Query: 262 YN--SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
N + VP PPG S S+ V W P G + ++ GY
Sbjct: 15821 ENRYGKSTYLNSEPTVAQYPFKVPG-PPGTPVVTLSSRDSMEVQWNEPISDGGSRVI-GY 15878
Query: 320 RVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
+ W Q TT GL Y V A G G + C
Sbjct: 15879 HLERKERNSILWVKLNKTPIPQTK-FKTT--GLEEGVEYEFRVSAENIVGIGKPSKVSEC 15935
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRM 436
+ D P +A + +RN + + W P+ G + GY + + +GR K
Sbjct: 15936 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGR---WMKAS 15992
Query: 437 LSPSTLSH-ETSRSPPRATHQFWVSASTRLG----EGEATRVVTVLPSDSV-PARIT--- 487
+ +H E + ++F V A G E+T +T D V P RI+
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITA--RDEVDPPRISMDP 16050
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA 546
+ IV E+ + + G P P W L +T R + S+D ++S+ +
Sbjct: 16051 KYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAV 16110
Query: 547 --DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQ-GDGGS 601
DSGNY +N+ G VT V+V P PP VV S A+ L W DGGS
Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 16170
Query: 602 PILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
I+ Y++ +RE W + T + L G Y I A N+ G G P +
Sbjct: 16171 DIINYIVE-RRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE 16229
Query: 660 HAYTKG--TVPVKPKHSQMITL-NTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
K VP PK ++ T+ + + VW DGG IL +V+E R+ +W
Sbjct: 16230 PVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC 16289
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ R+ V+GL Y+ R++A N AG
Sbjct: 16290 HKRLIGELRL-RVTGLIENHDYEFRVSAENAAG 16321
Score = 123 bits (296), Expect = 4e-27
Identities = 146/644 (22%), Positives = 246/644 (38%), Gaps = 41/644 (6%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+VTS S++ + N G + P+ + + GPP +R++ S
Sbjct: 18951 TVTSLSIKEASKEDVGTYELCVSNSAGSI--TVPITIIVLDR--PGPPGPIRIDEVSCDS 19006
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W PP+ D I Y V +E S + +++ AR+
Sbjct: 19007 ITISWNPPEYD-GGCQISNYIVEKKETTSTTWHIVSQA---------------VARTSIK 19050
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSW 304
+ L + Y V A N P PPG + + ++ V+W
Sbjct: 19051 IVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 19110
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
+ P G + ++ GY + Y + ++ A I+ +SGL Y V A
Sbjct: 19111 QVPVNDGGSRVI-GYHLEYKERSSILWSK-ANKILIADTQVKVSGLDEGLMYEYRVYAEN 19168
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSV 423
AG G + D P + +R + + W P G + GY +
Sbjct: 19169 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19228
Query: 424 IEDGREEGTHKRMLSPSTLS-HETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+ DGR + + + E + F +A+ + E + ++ D
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288
Query: 483 PARI---TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDG-- 536
P R+ F IV E + ++ + G P P +W +G+ +E R +S+D
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
LT+ D+G Y +++N+ G V +V P PP L + A+ L W
Sbjct: 19349 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWG 19408
Query: 595 -DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
Q DGG+ I Y KRE H W + E + + L G Y +T N+ G
Sbjct: 19409 RPQEDGGADI-DYYHRKKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYG 19467
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
G P + + A TVP P ++ ++ ++T+ W DGG I ++IE RE
Sbjct: 19468 VGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREK 19527
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+ +W V+ RV S +GL Y+ R+ A N AG +L
Sbjct: 19528 NSLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSL 19570
Score = 121 bits (292), Expect = 1e-26
Identities = 121/483 (25%), Positives = 198/483 (40%), Gaps = 28/483 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
PG + + ++ S+ ++W P G + I Q Y + + + IS
Sbjct: 21658 PGIPEPSNITGNSITLTWARPESDGGSEIQQ-YILERREKKSTRWVKVISKRPISETRFK 21716
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAAVSSRNKILVS 403
++GL Y V A AAG G + + C + P P +K +S+ + +
Sbjct: 21717 VTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLE 21776
Query: 404 WLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSA 461
W P G+ ++GY + M + G HK + T ++F VSA
Sbjct: 21777 WSKPVFDGGMEIIGYIIEMCKTDLG---DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 21833
Query: 462 STRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G+G++ V T+ D + A +F + V +I L G P P
Sbjct: 21834 INGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAV 21893
Query: 517 WTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W+ L +LR ++ S TLT+ D+G YT +VEN G +T+TV+V
Sbjct: 21894 WSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDT 21951
Query: 574 PQPP-ILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEH 629
P PP + D S L W + DGG+ I YV+ KRE W+ + +
Sbjct: 21952 PGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE-KREASRRSWQVISEKCTRQIF 22010
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWL 688
+ +L G Y ++A N G G P ++ P P+ ++ T ++ V WL
Sbjct: 22011 KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWL 22070
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG I +++E R+ W ++ Q T F+V L Y+ R+ A N+A
Sbjct: 22071 KPDHDGGSRITGYLLEMRQKGSDLWVEAGHTKQLT---FTVERLVEKTEYEFRVKAKNDA 22127
Query: 749 GHA 751
G++
Sbjct: 22128 GYS 22130
Score = 120 bits (288), Expect = 4e-26
Identities = 126/485 (25%), Positives = 194/485 (40%), Gaps = 31/485 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG + ++ S+ V W P G + I GY + G + + I
Sbjct: 20571 PPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKS-LGWFKVLKETIRDTRQ 20628
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILV 402
++GL ++Y VCA AAG G + P + D P PA I+ A S+++ I +
Sbjct: 20629 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20688
Query: 403 SWLPPSSPNGVLVGYTLYMSVIEDGREE--GTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P G V T Y+ I G EE T T + S P + F VS
Sbjct: 20689 GWSKPVYDGGSAV--TGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 20746
Query: 461 ASTRLGEG------EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G+G E + +L + + + + +++ E++ + G P P
Sbjct: 20747 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDV-ALRTSVIAKAGEDVQVLIPFKGRPPPT 20805
Query: 515 TTWTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + L S R +N S LTI D+G Y ++EN G + + TV VK
Sbjct: 20806 VTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVK 20864
Query: 572 VPPQPPI---LAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P L V ++ L W DGGSPI+ YVI KR+ W + +
Sbjct: 20865 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE-KRDATKRTWSVVSHKCS 20923
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH-SQMITLNTTTV 684
++ L +L T + + A N IG G PC+ VP + S + T+ +
Sbjct: 20924 STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI 20983
Query: 685 TVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
W DGG I +V+E + + W S++ + VS L + + R+ A
Sbjct: 20984 LSWTKPDFDGGSVITEYVVERKGKGEQTW---SHAGISKTCEIEVSQLKEQSVLEFRVFA 21040
Query: 745 HNNAG 749
N G
Sbjct: 21041 KNEKG 21045
Score = 118 bits (285), Expect = 9e-26
Identities = 164/709 (23%), Positives = 270/709 (38%), Gaps = 57/709 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N +VID ++ +SW++P Y G I YIV+ + W TP I +
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVNVGEWTMCTPPTGI---N 16397
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T+ V+ L Y+ RI A N+ G E + EE P D+ +E + +
Sbjct: 16398 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINI 16457
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
G L +V + T + G + ++ + L
Sbjct: 16458 RA-----------GGSLRLFV---PIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 16503
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ ++ + + NS + D PS PP L+ ++ SV ++WEP
Sbjct: 16504 DNVNRYDSGKYTLTLENS---SGTKSAFVTVRVLDTPS-PPVNLKVTEITKDSVSITWEP 16559
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + G + I + Y V T + AV + L+ +Y V A
Sbjct: 16560 PLLDGGSKI-KNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16616
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIE 425
G G+ A +VP P I +RN + +SW P G ++ Y + M
Sbjct: 16617 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16676
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE----ATRVVT---VLP 478
+ + + +++ T + F V A G + A +V V+
Sbjct: 16677 SEKWSECARVKSLQAVITNLTQGEE----YLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE 16732
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD--- 535
D PA +S+S + K + +S G P P TWT +G+ L+ T R NV+
Sbjct: 16733 PDVKPA-FSSYSVQVGQDLKMEVPIS----GRPKPTITWTKDGLPLKQTTRINVTDSLDL 16787
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADSLHLQW 593
TL+I T D G Y +V N+ G+ + + P PP V D A+S+ L W
Sbjct: 16788 TTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSW 16847
Query: 594 SDQ-GDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ GG I Y++ KR+ W+ + + + L GT YQ I A NR
Sbjct: 16848 NPPLYTGGCQITNYIVQ-KRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRY 16906
Query: 651 GT--GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYRE 707
G L D + A P P ++ ++ + W + +GG ++ + +E +E
Sbjct: 16907 GQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKE 16966
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYN 756
+ W V+ ++ + F L Y+ R+ A N G A N
Sbjct: 16967 RNSILWTKVNKTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 17014
Score = 118 bits (285), Expect = 9e-26
Identities = 143/615 (23%), Positives = 236/615 (38%), Gaps = 52/615 (8%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ V T PS P +R + + +I++W+ P+ D G I Y + +E + +
Sbjct: 21151 PITVITLGP-PSKPKGPIRFDEIKADSVILSWDVPE-DNGGGEITCYSIEKRETSQTNWK 21208
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
++ S AR+ + L K A Y V+A N
Sbjct: 21209 MVCSS---------------VARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVA 21253
Query: 279 MED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV 336
+P PPG ++S + ++W+ P G + + G+ V +
Sbjct: 21254 KHQFRIPG-PPGKPVIYNVTSDGMSLTWDAPVYDGGSEVT-GFHVEKKERNSILWQK-VN 21310
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAA 393
T ISG +GL +Y V A +AG + P + D P P I
Sbjct: 21311 TSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDV- 21369
Query: 394 VSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR 452
+R I + W PP G +VGY++ G E S + + P
Sbjct: 21370 --TRETITLKWNPPLRDGGSKIVGYSIEK---RQGNERWVRCNFTDVSECQYTVTGLSPG 21424
Query: 453 ATHQFWVSASTRLGE---GEATRVVTVLPSDSVPARIT---SFSRNIVTPWKENISLSCN 506
++F + A +G + + + ++VP + + ++ E++ +
Sbjct: 21425 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21484
Query: 507 KVGVPAPATTWTMNGVGLESTLRK---NVSSDGTLTISMTQSADSGNYTCSVENIHGRDE 563
G P P TW +GV +E + NV +L + G YT +N G +
Sbjct: 21485 VQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 21544
Query: 564 VTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHGD--WE 618
V+V+ P + + + + + L W + DG +PI Y+I KRE W
Sbjct: 21545 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE-KRETSRLAWA 21603
Query: 619 ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKGTVPVKP--KHS 674
++ + + L G YQ ++A N+ G G P D V A + TVP P
Sbjct: 21604 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 21663
Query: 675 QMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
IT N+ T+T W DGG I +++E RE +W V + +E F V+GLT
Sbjct: 21664 SNITGNSITLT-WARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTE 21722
Query: 735 AAHYQLRITAHNNAG 749
Y+ + A N AG
Sbjct: 21723 GNEYEFHVMAENAAG 21737
Score = 118 bits (283), Expect = 2e-25
Identities = 156/650 (24%), Positives = 247/650 (38%), Gaps = 60/650 (9%)
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+T+ S++ I N +GQ S +++ T ++ P P V+ + S+ +
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTAS--IEIVTLDK-PDPPKGPVKFDDVSAESI 16843
Query: 187 IVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++W PP L+ G I Y V Q+ ++ +TV V A AR+
Sbjct: 16844 TLSWNPP---LYTGGCQITNYIV--QKRDTTTTVW-------------DVVSATVARTTL 16885
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL-PPGALQCNALSSQSVRVS 303
++ L+ Y + A N PPG A+S S+ +
Sbjct: 16886 KVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQ 16945
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G + ++ GY + + V K I +H T L Y V
Sbjct: 16946 WHEPVNNGGSPVI-GYHLERKERNSILWTK--VNKTI--IHDTQFKAQNLEEGIEYEFRV 17000
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTL 419
A G G + C+ D P + + RN+I + W P G ++ GY +
Sbjct: 17001 YAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIV 17060
Query: 420 YMSVIEDGR-EEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLG----EGEATRV 473
+ DGR + + ++ T+S T ++F V A G ++T
Sbjct: 17061 EKRDLPDGRWMKASFTNVIETQFTVSGLTEDQ----RYEFRVIAKNAAGAISKPSDSTGP 17116
Query: 474 VTVLPSDSVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR- 529
+T +P RI+ F IV E L + G P P W +E + R
Sbjct: 17117 ITAKDEVELP-RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 17175
Query: 530 --KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSY 585
KN L + D G Y N+ G V+V P PP + V
Sbjct: 17176 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVT 17235
Query: 586 ADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQL 642
++ L WS DGGS I YV+ KRE W + E T+ + L G Y
Sbjct: 17236 SEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVF 17294
Query: 643 YITAFNRIGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
I A N+ G G P + K +P PK ++ + ++TV W DGG I+
Sbjct: 17295 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEII 17354
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++E R+ S +W + N + T+ V+GLT Y+ R++A N AG
Sbjct: 17355 GYIVEKRDRSGIRW-IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAG 17403
Score = 117 bits (282), Expect = 2e-25
Identities = 150/625 (24%), Positives = 245/625 (39%), Gaps = 46/625 (7%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
+ A N +G+ +QV ++P P ++ + SS + +W+PP+ D I
Sbjct: 14641 LTARNIVGEVGDVITIQV---HDIPGPPTGPIKFDEVSSDFVTFSWDPPEND-GGVPISN 14696
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y V ++ +S + V +A+ +RT T ++ +GL+ + V Q
Sbjct: 14697 YVVEMRQTDSTTWVELATT------VIRT-----TYKATRLTTGLEYQ--FRVKAQNRYG 14743
Query: 265 RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA 324
VP PPG Q A++ S+ +SW P G + IL GY V
Sbjct: 14744 VGPGITSAWIVANYPFKVPG-PPGTPQVTAVTKDSMTISWHEPLSDGGSPIL-GYHVERK 14801
Query: 325 PVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
W A+ + G SGL Y V A AG + P D
Sbjct: 14802 ERNGILWQTVSKAL---VPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALD 14858
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST 441
P +R+ + + W P G + Y + + +GR + + +
Sbjct: 14859 PIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE 14918
Query: 442 LSHETSRSPPRATHQFWVSASTRLGE----GEATRVVTVLPSDSVPA-RI-TSFSRNIVT 495
+ S A ++F V A G E + +T P ++ F ++
Sbjct: 14919 FT--VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGTLTISMTQSA--DSGNYT 552
E L + G P P W+ +G LE T + + +D + + S DSG YT
Sbjct: 14977 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 553 CSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYADSLHLQW-SDQGDGGSPILGYVIN 609
+ N G + + V+V P PP LAV + ++ L W DGG+ I Y++
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 15096
Query: 610 YKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKG 665
KRE W + E ++ + L G Y + A N+ G G P + V A
Sbjct: 15097 -KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY 15155
Query: 666 TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
P PK+ ++ T+ ++ V W DGG I+ +++E R+ + +W + N T+
Sbjct: 15156 GPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRW-IKCNKKTLTD 15214
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ VSGLT Y+ RI A N AG
Sbjct: 15215 LRYKVSGLTEGHEYEFRIMAENAAG 15239
Score = 116 bits (280), Expect = 4e-25
Identities = 152/629 (24%), Positives = 245/629 (38%), Gaps = 58/629 (9%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I AEN G + ++V + P GPP V++ S +++WEPP D I
Sbjct: 12871 ITAENSSGSKSATIKLKVL---DKP-GPPASVKINKMYSDRAMLSWEPPLED-GGSEITN 12925
Query: 205 YYVGFQELNS-NSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y V +E + N + A+ P + + +EG H Y + A N
Sbjct: 12926 YIVDKRETSRPNWAQVSATVPITSCSVEKLIEG---------------HE-YQFRICAEN 12969
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSS---QSVRVSWEPPPMRGRNGILQGYR 320
P PPG +S+ + VSW+PP G + I GY
Sbjct: 12970 KYGVGDPVFTEPAIAKN--PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPIT-GYL 13026
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYC 377
+ T K I +GL+ T Y V A AG G + Y
Sbjct: 13027 LEKRE-TQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYA 13085
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTH-KR 435
+ P+ PA K ++R+ + +SW P+ G ++GY ++E R + + R
Sbjct: 13086 RDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGY-----LVEVKRADSDNWVR 13140
Query: 436 MLSPSTLSH---ETSRSPPRATHQFWVSASTRLGEGEATRVVTV-LPSDS-VPAR---IT 487
P L E + +QF V A ++G + + V P D +P
Sbjct: 13141 CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEHDA 13200
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS---DGTLTISMTQ 544
+ ++ + L G P P TW+ V L + ++ S D L
Sbjct: 13201 DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVN 13260
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQ-GDGGSP 602
D+G Y ++EN G+ E T V+V P PPI + V + DS ++ W DGGSP
Sbjct: 13261 KYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPINVTVKEISKDSAYVTWEPPIIDGGSP 13320
Query: 603 ILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
I+ YV+ + E W + E + +PNL G Y + A N G G P + A
Sbjct: 13321 IINYVVQKRDAERKSWSTVTTECSKTSFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDA 13380
Query: 662 YTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSV 720
P ++ +++ ++ ++ W DGG I+ +V+++ + +W+ V S+
Sbjct: 13381 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL 13439
Query: 721 QATERVFSVSGLTPAAHYQLRITAHNNAG 749
+S LT Y R++A N G
Sbjct: 13440 SLQ---YSAKDLTEGKEYTFRVSAENENG 13465
Score = 115 bits (277), Expect = 8e-25
Identities = 159/702 (22%), Positives = 266/702 (37%), Gaps = 57/702 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N ++D +I ++W +P Y G S I+ Y+V+ +A E W TPQ +
Sbjct: 17423 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL---R 17479
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
VT + L Y +R+ A N++G E + E+ P D+ E + +
Sbjct: 17480 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG--I 17537
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+V G ++ F+ I +T + G ++ ++
Sbjct: 17538 VVR---------AGGSARIHIPFK---GRPMPEITWSREEGEFTDKVQIEKGVNYTQLSI 17585
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ A +++ NS + D P PP L + S + WEP
Sbjct: 17586 DNCDRNDAGKYILKLENS---SGSKSAFVTVKVLDTPG-PPQNLAVKEVRKDSAFLVWEP 17641
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P + G ++ Y + T Y N V+ + S + L Y V A
Sbjct: 17642 PIIDG-GAKVKNYVIDKRESTRKAYAN---VSSKCSKTSFKVENLTEGAIYYFRVMAENE 17697
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVI 424
G GV V + PS P + S+ + W P G V GY + M
Sbjct: 17698 FGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM--- 17754
Query: 425 EDGREEGTHK-RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRV-VTVLPSDS 481
+ +GT K +++ S + + +QF V A G+ + + V V+ D
Sbjct: 17755 ---QPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 17811
Query: 482 V--PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P+ F+ + E++ + +G P P +W +G L+ T R NV T T
Sbjct: 17812 TIQPSLKLPFNTYSIQAG-EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870
Query: 540 ISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
+ + D G YT + N G +V V P PP+ + + AD + + W
Sbjct: 17871 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWE 17930
Query: 595 DQG-DGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
GG I Y++ KR+ W + + + L GT YQ I A NR G
Sbjct: 17931 PPAYTGGCQISNYIVE-KRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYG 17989
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
P D V P P + +++ + V W + DGG I+ + +E +E
Sbjct: 17990 KSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEK 18049
Query: 709 SQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ W +L +Q T+ F +GL Y+ +++A N G
Sbjct: 18050 NSILWVKLNKTPIQDTK--FKTTGLDEGLEYEFKVSAENIVG 18089
Score = 115 bits (276), Expect = 1e-24
Identities = 123/493 (24%), Positives = 197/493 (39%), Gaps = 35/493 (7%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYG-NEDAVTKQISGL 343
P + +S + + V W PP G I GY + T W N+ A+ ++ +
Sbjct: 11902 PDPPEVTKVSKEEMTVVWNPPEYDGGKSIT-GYFLEKKEKHSTRWVPVNKSAIPERRMKV 11960
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
L Y V A G G + + PV + P P + + ++++ I
Sbjct: 11961 QNLLPD----HEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 12016
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHE---TSRSPPRATH 455
+ W P G ++GY + M I D + KR + + L + + +
Sbjct: 12017 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 12076
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSV--PARI---TSFSRNIVTPWKENISLSCNKVGV 510
+F V A ++G G + + + P I S + ++ I L G
Sbjct: 12077 EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR 12136
Query: 511 PAPATTWTMNGVGLESTLRKN----VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
PAP TW VG+++ +RK V + L I + DSG Y+ ++ N G V
Sbjct: 12137 PAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 12194
Query: 567 TVEVKVPPQPPI-LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKR-EHGDWEELQVE 623
V V P P L V D S H+ W+ + DGGS + Y++ + + W + E
Sbjct: 12195 NVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE 12254
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
+ + NL G Y +TA N G G+P D+ V A + P P+ + +
Sbjct: 12255 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEATEMT 12314
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+ T+ WL DGG I ++I YRE QP R SV + V+GL Y+
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDGYIISYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYK 12373
Query: 740 LRITAHNNAGHAL 752
R+ A N G +L
Sbjct: 12374 FRVAARNAVGVSL 12386
Score = 114 bits (275), Expect = 1e-24
Identities = 118/490 (24%), Positives = 191/490 (38%), Gaps = 33/490 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQ 339
VPS P A + ++ + V+W+ P G + I+ GY + W D + +
Sbjct: 12594 VPSEPKNA-RVTKVNKDCIFVAWDRPDSDGGSPII-GYLIERKERNSLLWVKANDTLVRS 12651
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
+GL YS + A AG + P T P + +++
Sbjct: 12652 TE---YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST 12708
Query: 400 ILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+ + W P G ++GY + + + + + + +A +QF
Sbjct: 12709 VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFR 12768
Query: 459 VSASTRLG---EGEATRVVTVLPSDSVPARI---TSFSRNIVTPWKENISLSCNKVGVPA 512
A T + E + VT+L +++VP RI + + N+ L G P
Sbjct: 12769 AIARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 12827
Query: 513 PATTWTMNGV------GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
P +W +G G++ +++N+ TL + DSG+YT + EN G T
Sbjct: 12828 PTVSWKKDGTLLKPAEGIKMAMQRNLC---TLELFSVNRKDSGDYTITAENSSGSKSATI 12884
Query: 567 TVEVKVPPQPPILAVVDS-YADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQV 622
++V P PP ++ Y+D L W DGGS I Y+++ KRE +W ++
Sbjct: 12885 KLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD-KRETSRPNWAQVSA 12943
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L G YQ I A N+ G G P A K + + N T
Sbjct: 12944 TVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNIT 13003
Query: 683 T--VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+TV W DGG I +++E RE W V N ER +GL Y+
Sbjct: 13004 KDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKV-NRKPIIERTLKATGLQEGTEYE 13062
Query: 740 LRITAHNNAG 749
R+TA N AG
Sbjct: 13063 FRVTAINKAG 13072
Score = 113 bits (272), Expect = 3e-24
Identities = 150/616 (24%), Positives = 229/616 (37%), Gaps = 48/616 (7%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S+ ++V ++ P P ++++ +T + ++WEPP+ D + GY V ++
Sbjct: 23324 SETIKVIILDK-PGPPTGPIKIDEIDATSITISWEPPELD-GGAPLSGYVVEQRD----- 23376
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
A PG + RS + L + Y V A N
Sbjct: 23377 ----AHRPGWLPVS------ESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVI 23426
Query: 277 XXMEDV--PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNE 333
+ P PP LQ +S + ++W PP G + + GY V V D +
Sbjct: 23427 ECRSSIRIPG-PPETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRADRWVRV 23484
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADI 390
+ V ++ +T GL Y V A A G G + P D P P +
Sbjct: 23485 NKVPVTMTRYRST--GLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 23542
Query: 391 KAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
+ ++R + ++W P G V GY + M ++ + E T + +
Sbjct: 23543 RVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD--QHEWTKCNTTPTKIREYTLTHL 23600
Query: 450 PPRATHQFWVSASTRLGEGEATRV---VTVLPSDSVPARITS--FSRNIVTPWKENISLS 504
P A ++F V A G GE V V V P + I I L+
Sbjct: 23601 PQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLT 23660
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDE 563
G P P WT G + S T L I DSG Y +EN G+
Sbjct: 23661 IPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKA 23720
Query: 564 VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR-EHGDWEE 619
V V V P P L D S+ + W D GG+ ILGY++ + W
Sbjct: 23721 VYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYT 23780
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMI 677
+ + V+ L Y ++A N+ G P T T P +P +
Sbjct: 23781 IDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPE 23840
Query: 678 TLNTTTVTVWLDSWG----DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
L+ T +V L SW DGG + + IE +E S + + N Q T +++V+GL
Sbjct: 23841 VLDVTKSSVSL-SWSRPKDDGGSRVTGYYIERKETSTDKV-VRHNKTQITTTMYTVTGLV 23898
Query: 734 PAAHYQLRITAHNNAG 749
P A YQ RI A N+ G
Sbjct: 23899 PDAEYQFRIIAQNDVG 23914
Score = 111 bits (266), Expect = 2e-23
Identities = 155/701 (22%), Positives = 253/701 (36%), Gaps = 48/701 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ-YKEAPESWPSTPQKVIVPGSV 127
P P N ++ D+ T + WT+P + G SPI+ Y+V+ K W + ++
Sbjct: 11307 PGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELI--RQ 11364
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L Y RI A N +G+ EP + + +++ PP+ VE + +
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH-PPE---VELDVTCRDV 11420
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+T Q + G VL+ V ++ + +
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK------RVDLIQDLPRVELQIKEA 11474
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
H Y ++ A NS + D P P L+ ++ ++ +SWE P
Sbjct: 11475 VRADHGKY--IISAKNS---SGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENP 11528
Query: 308 PMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
G + I + V Y W VTK++ + L Y VCA
Sbjct: 11529 LDNGGSEITN-FIVEYRKPNQKGWSIVASDVTKRL-----IKANLLANNEYYFRVCAENK 11582
Query: 366 AGDGVRA---APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL-VGYTLYM 421
G G P+ D P P ++ A + + + W P G + Y +
Sbjct: 11583 VGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVER 11642
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
+ E HK + + + R ++F V GE + + V+ +
Sbjct: 11643 RLKGSDDWERVHKGSIKET--HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKED 11700
Query: 482 VPARITSFSRNIVTPWK--ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---- 535
+ + + V K + I L G P P WT + + T V D
Sbjct: 11701 LQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760
Query: 536 -GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQW 593
+++ + +D G Y + N G TV V P P L +VD +D + W
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCW 11820
Query: 594 SD-QGDGGSPILGYVINY-KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ DGG I Y++ + + W T + L G Y + A N+IG
Sbjct: 11821 DPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG 11880
Query: 652 TGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREM 708
TG P + V A TK P +P ++ ++ +T VW DGG I + +E +E
Sbjct: 11881 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEK 11940
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ S ER V L P YQ R+ A N G
Sbjct: 11941 HSTRWVPVNKSA-IPERRMKVQNLLPDHEYQFRVKAENEIG 11980
Score = 111 bits (266), Expect = 2e-23
Identities = 114/482 (23%), Positives = 185/482 (38%), Gaps = 20/482 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P L+ ++ SV + W+ P + G + I Y V T + T +
Sbjct: 14369 DTPG-PVLNLRPTDITKDSVTLHWDLPLIDGGSRITN-YIVEKREATR--KSYSTATTKC 14424
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
++GL Y V A G G + PS P + +++ +
Sbjct: 14425 HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTV 14484
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
++W P G + GY + G ++ TH + T Q
Sbjct: 14485 SLAWPKPKHDGGSKITGYVIEAQ--RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMA 14542
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTW 517
S +R V V +P + + ++ +NI + +G P P TW
Sbjct: 14543 VNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW 14602
Query: 518 TMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L+ T R N + T L I+ +DSG Y + NI G T++V P
Sbjct: 14603 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 14662
Query: 575 QPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
PP + + +D + W + DGG PI YV+ ++ + W EL + +
Sbjct: 14663 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14722
Query: 631 LPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-W 687
L G YQ + A NR +G G+ + A VP P Q+ + ++T+ W
Sbjct: 14723 ATRLTTGLEYQFRVKAQNRYGVGPGITSAWIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14782
Query: 688 LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNN 747
+ DGG IL + +E +E + W+ VS ++ +F SGLT Y+ R+ A N
Sbjct: 14783 HEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGIAYEFRVIAENM 14841
Query: 748 AG 749
AG
Sbjct: 14842 AG 14843
Score = 110 bits (265), Expect = 2e-23
Identities = 124/473 (26%), Positives = 190/473 (40%), Gaps = 24/473 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI-SGLHTTLSGLRRY 353
++S S+ V W P G + IL GY + V + + V K + + L + GL
Sbjct: 8417 VTSNSMLVKWNEPKDNG-SPIL-GYWLEKREVNSTHWSR--VNKSLLNALKANVDGLLEG 8472
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSWLPPS-SP 410
Y VCA AAG G + P T D P P + +S I + W PP+ +
Sbjct: 8473 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNG 8532
Query: 411 NGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE- 469
G +VGY + ++ + ++M+ + + R A ++ VSA GEG
Sbjct: 8533 GGEIVGYFVDKQLVGTNKWSRCTEKMIKVRQYTVKEIRE--GADYKLRVSAVNAAGEGPP 8590
Query: 470 -ATRVVTVLPSDSVPA--RITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
T+ VTV PA S I + + + G P P WT L+
Sbjct: 8591 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK 8650
Query: 527 --TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVD 583
+ NV + L I D G Y + N G VEV P P + L V
Sbjct: 8651 DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVV 8710
Query: 584 SYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
+ L WSD + DGGS I G++I K + W + +E S+ + L G Y+
Sbjct: 8711 TNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-PIETERSKCDITGLLEGQEYK 8769
Query: 642 LYITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
+ A N+ G G P +I + A P P+ +T+T+ W + +GG I
Sbjct: 8770 FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERQRSTITLDWKEPRSNGGSPI 8829
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
++IE R +P + V+ + T F V L Y+ R+ A N G +
Sbjct: 8830 QGYIIEKRRHDKPDFERVNKRLCPTTS-FLVENLDEHQMYEFRVKAVNEIGES 8881
Score = 110 bits (265), Expect = 2e-23
Identities = 143/614 (23%), Positives = 230/614 (37%), Gaps = 46/614 (7%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S P+ V + P P ++V ++ + + W PP +D NI Y + +E + S
Sbjct: 18294 SIPITVKVLDR-PGSPEGPLKVTGVTAEKCYLAWNPPLQD-GGANISHYIIEKRETSRLS 18351
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
+++ +Y V + L G + Y V A N
Sbjct: 18352 WTQVSTEVQALNYKVTKL-----------LPGNE----YIFRVMAVNKYGIGEPLESGPV 18396
Query: 277 XXMEDV-PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDA 335
P PP + +A++ S+ V+W P G I +GY + +
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEI-EGY-ILEKRDKEGVRWTKC 18454
Query: 336 VTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKA 392
K ++ L ++GL +Y V A AAG G + P + D P P++ K
Sbjct: 18455 NKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKV 18514
Query: 393 AVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHE---TSR 448
+SR+ + ++W P G V GY + V E +E T P+ L + ++
Sbjct: 18515 TDTSRSSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWT--TCTPPTGLQGKQFTVTK 18570
Query: 449 SPPRATHQFWVSASTRLGEGE-ATRVVTVLPSDSV-PARI---TSFSRNIVTPWKENISL 503
+ F + A G GE AT +V+ + + P I + +V + L
Sbjct: 18571 LKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRL 18630
Query: 504 SCNKVGVPAPATTWTM-NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD 562
G P P W G+ + + SS L I DSG Y ++EN G
Sbjct: 18631 FVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK 18690
Query: 563 EVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKRE--HGDWE 618
V V P P+ L + + DS+ L W DGG+ I Y++ KRE +
Sbjct: 18691 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYA 18749
Query: 619 ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMIT 678
+ + + NL G Y + A N G GLP + P+ P ++
Sbjct: 18750 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVD 18809
Query: 679 LNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
+ T T+ W DGG I +V+E + +W S Q ++SGLT
Sbjct: 18810 VTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKW---STCTQVKTLEATISGLTAGEE 18866
Query: 738 YQLRITAHNNAGHA 751
Y R+ A N G +
Sbjct: 18867 YVFRVAAVNEKGRS 18880
Score = 110 bits (264), Expect = 3e-23
Identities = 119/481 (24%), Positives = 182/481 (37%), Gaps = 21/481 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D PS P L + SV +SWEPP + G + Y V T +T
Sbjct: 18700 DSPSAPVN-LTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTR--KAYATITNNC 18755
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
+ + L+ +Y V A G G+ A + P P + +RN
Sbjct: 18756 TKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTA 18815
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
+ W P S G + GY + M G E+ + + TL S + F V
Sbjct: 18816 TIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVK--TLEATISGLTAGEEYVFRV 18871
Query: 460 SASTRLGEGEATRV-VTVLPSD-SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+A G + ++ V V+ D + + +E + + G P W
Sbjct: 18872 AAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNW 18931
Query: 518 TMNGVGLESTLRKNVSSDGTLT---ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+G L+ T R NVSS T+T I D G Y V N G V T+ V P
Sbjct: 18932 RKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRP 18991
Query: 575 QPPILAVVDSYA-DSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
PP +D + DS+ + W+ + DGG I Y++ K W + + +
Sbjct: 18992 GPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKI 19051
Query: 632 PNLWCGTRYQLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WL 688
L G+ YQ + A NR G V A + P P +++ +T+ V W
Sbjct: 19052 VRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQ 19111
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG ++ + +EY+E S W +N + + VSGL Y+ R+ A N A
Sbjct: 19112 VPVNDGGSRVIGYHLEYKERSSILWS-KANKILIADTQVKVSGLDEGLMYEYRVYAENIA 19170
Query: 749 G 749
G
Sbjct: 19171 G 19171
Score = 108 bits (260), Expect = 9e-23
Identities = 158/700 (22%), Positives = 270/700 (38%), Gaps = 47/700 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYK-EAPESWPSTPQKVIVPGSV 127
P P +V D + + W+ P G S + YIV+YK E E W K +
Sbjct: 9924 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV---RG 9980
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T V L+ Y R+ A N G EP + V ++ P D++++A ++
Sbjct: 9981 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSP--DLQLDASVRDRIV 10038
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V R I+ Y G + + P A T+E + S +
Sbjct: 10039 VHAGGVIR------IIAYVSGKPPPTVTWNMNERTLPQEA-----TIETTAISSSMVIKN 10087
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ H V + ++ + DVP + L+++S +++W P
Sbjct: 10088 CQRSHQG----VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I V +D VT ++ + T+ GL + Y + A + G
Sbjct: 10144 EDDGGSPITN--YVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIG 10200
Query: 368 DG--VRAAPVYCHTEE-DVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSV 423
G V + E VP P D++ ++N + ++W PP G ++ Y L +
Sbjct: 10201 MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRL 10260
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRA--THQFWVSASTRLGEGE---ATRVVTVLP 478
I G E+ HK + + + LS + + + T+++ VSA +G+G+ T+ +T
Sbjct: 10261 I--GTEK-FHK-VTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD 10316
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGT 537
+ P F + E +L+ G P P +W + + R ++ ++ T
Sbjct: 10317 ELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPAT 10376
Query: 538 LTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW 593
L + ++ +DSG Y VEN G + V V P PP+ ++ + D + + W
Sbjct: 10377 LALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDHPGPPVGPVSFDEVTKDYMVISW 10436
Query: 594 SDQ-GDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
DGGS I Y+I K D W + + + + L G Y I A N G
Sbjct: 10437 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYG 10496
Query: 652 TGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMS 709
P D + A + VP P + + + V + DGG I +++E RE
Sbjct: 10497 ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETM 10556
Query: 710 QPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ F V L Y+ R++A N G
Sbjct: 10557 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIG 10596
Score = 108 bits (260), Expect = 9e-23
Identities = 122/487 (25%), Positives = 195/487 (40%), Gaps = 32/487 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P PP L+ ++ SV ++W+PP + G + I + Y V T A +
Sbjct: 15453 DTPG-PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKREST-----RKAYSTVA 15505
Query: 341 SGLHTT---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ H T + L+ +Y V A G G+ A + P P I +R
Sbjct: 15506 TNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTR 15565
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
N + +SW P G ++GY + M + ++ +T++ +
Sbjct: 15566 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEE----YS 15621
Query: 457 FWVSASTRLGEGEATRV-VTVLPSDSV-PARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
F VSA G + ++ V V+ D V P E++ + +G P PA
Sbjct: 15622 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPA 15681
Query: 515 TTWTMNGVGLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + V L+ T R N S + LTI D G+Y + N G T V V
Sbjct: 15682 VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVL 15741
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEELQVEAGT 626
P PP + + + ADS+ L W + DGGS I Y++ KR+ W+ +
Sbjct: 15742 DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE-KRDTSTTTWQIVSATVAR 15800
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG--TGLPCDIVHAYTKGTVPVKPKHSQMITLNT--T 682
+ L G YQ I A NR G T L + A VP P + ++TL++ +
Sbjct: 15801 TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDS 15859
Query: 683 TVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
W + DGG ++ + +E +E + W + N + F +GL Y+ R+
Sbjct: 15860 MEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTKFKTTGLEEGVEYEFRV 15918
Query: 743 TAHNNAG 749
+A N G
Sbjct: 15919 SAENIVG 15925
Score = 105 bits (253), Expect = 7e-22
Identities = 108/394 (27%), Positives = 164/394 (41%), Gaps = 19/394 (4%)
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEG 431
PV+ PS P + +A ++ N + ++W PP G ++GY + Y V ++
Sbjct: 10606 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 10665
Query: 432 THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VLPSDSV--PARI-- 486
H P T ++ + T++F V A GE + V VL D + P I
Sbjct: 10666 NHTPESCPET-KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILD 10724
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQS 545
+ +R + + LS GVP P TW + R +V+ G+ L I
Sbjct: 10725 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAH 10784
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPI 603
D G Y+ +VEN G V+ V V P PP L V + DS +L W + DGGS I
Sbjct: 10785 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 10844
Query: 604 LGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---V 659
YV+ + W L + H +L G +Y + A N+ G G + +
Sbjct: 10845 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 10904
Query: 660 HAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN 718
A P PK + ++ T V+ VW DGG I +++EY+E W +
Sbjct: 10905 KALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW-IKFK 10963
Query: 719 SVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+V E V V+GL Y+ R+ A N G L
Sbjct: 10964 TVTNLECV--VTGLQQGKTYRFRVKAENIVGLGL 10995
Score = 105 bits (253), Expect = 7e-22
Identities = 161/683 (23%), Positives = 267/683 (39%), Gaps = 54/683 (7%)
Query: 95 AGNSPIINYI-VQYKEAPESWPSTPQKVIVPGSVT------SASVQNLQPAT---SYHLR 144
AG++ ++N I + K P+S S K I P +T ++S+ ++ AT +
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 13954
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I A N G + V+VT + VP GPP V + S+ + +TW PP D G+ +
Sbjct: 13955 ITATNPFGTKV--EHVKVTVLD-VP-GPPGPVEISNVSAEKATLTWTPPLED--GGSPIK 14008
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y+ L T S + TV R + L + Y V A N
Sbjct: 14009 SYI----LEKRET----------SRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNH 14054
Query: 265 RXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
++ P PP + + ++ + VSW+ P G + I GY V
Sbjct: 14055 YGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEIT-GYHVER 14113
Query: 324 APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV 383
A+ +S L ++GL+ + Y V A AG G + +D
Sbjct: 14114 REKKSLRWVR-AIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 14172
Query: 384 ---PSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLS 438
P P++ +++ ++W P G+ + GY + + V ++ + T L
Sbjct: 14173 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 14232
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLPSDSVP--ARITSFSRNIV 494
+ ++ + + F +SA G GE + V ++ + P R +V
Sbjct: 14233 ITQFVVPDLQTKEK--YNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLV 14290
Query: 495 TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSADSGNYTC 553
+I + G PAP TWT + + L++ +N S L I D+G +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 14350
Query: 554 SVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYK 611
++EN G+ V V P P + L D DS+ L W DGGS I Y++ K
Sbjct: 14351 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVE-K 14409
Query: 612 RE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV 669
RE + + + + L G Y + A N G G P + P
Sbjct: 14410 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 14469
Query: 670 KPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
P ++ + +TV++ W DGG I +VIE + QW ++ +V+ E V
Sbjct: 14470 PPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT-TVKGLECV-- 14526
Query: 729 VSGLTPAAHYQLRITAHNNAGHA 751
V LT Y ++ A N+AG +
Sbjct: 14527 VRNLTEGEEYTFQVMAVNSAGRS 14549
Score = 105 bits (253), Expect = 7e-22
Identities = 123/489 (25%), Positives = 185/489 (37%), Gaps = 37/489 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISG 342
PPG ++S + V W P G I+ GY + W N+ + Q +
Sbjct: 18010 PPGTPFVTSISKDQMLVQWHEPVNDGGTKII-GYHLEQKEKNSILWVKLNKTPI--QDTK 18066
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT GL Y V A G G + C D P +A V +RN + +
Sbjct: 18067 FKTT--GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTL 18124
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGR-EEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P+ G + GY + + DGR + + +L S ++F V
Sbjct: 18125 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE---FTVSGLVEDQRYEFRVI 18181
Query: 461 ASTRLGE----GEATRVVTVLPSDSVP--ARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G +++ +T P + + IV E L + G P P
Sbjct: 18182 ARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPD 18241
Query: 515 TTWTMNGVGLESTLR----KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
W+ +G LE T K+ TL + D G Y + N+ G + TV+V
Sbjct: 18242 VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Query: 571 KVPPQPPI--LAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAG 625
P P L V A+ +L W+ DGG+ I Y+I KRE W ++ E
Sbjct: 18302 LDRPGSPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE-KRETSRLSWTQVSTEVQ 18360
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD-----IVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A N+ G G P + + Y P P+ S IT +
Sbjct: 18361 ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS-AITKD 18419
Query: 681 TTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQL 740
+ VT W DGG I +++E R+ +W N T+ V+GLT Y+
Sbjct: 18420 SMVVT-WARPVDDGGTEIEGYILEKRDKEGVRW-TKCNKKTLTDLRLRVTGLTEGHSYEF 18477
Query: 741 RITAHNNAG 749
R+ A N AG
Sbjct: 18478 RVAAENAAG 18486
Score = 104 bits (249), Expect = 2e-21
Identities = 115/486 (23%), Positives = 191/486 (39%), Gaps = 35/486 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PP L+ + + S ++W+ P G ++ Y V V + + T + H
Sbjct: 10815 PPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVASAQWSPLSATSKKKS-HF 10872
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
L Y V A G G P+ P P D+ + ++ +
Sbjct: 10873 A-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSL 10931
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK--RMLSPSTLSHETSRSPPRATHQFWV 459
W P G + GY + + +EEGT + + + L + T++F V
Sbjct: 10932 VWNKPDRDGGSPITGYLV------EYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRV 10985
Query: 460 SASTRLGEGEATRVVTVLPSDS-VPARI---TSFSRNIVTPWKENISLSCNKVGVPAPAT 515
A +G G + + + VP + +V + GVP P
Sbjct: 10986 KAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 11045
Query: 516 TWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
WT +G +++ V +D LTI D+G Y +V N G V + V
Sbjct: 11046 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 11105
Query: 573 PPQPPI--LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSE 628
P PP + ++D + + + W + DGGSP++ Y++ + D W + + ++
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 11165
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTT 683
+P+L G Y + A N+IG G P D H ++ + P KP + IT N T
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAAT 11224
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
V+ W DGG I + +E RE++ +W V N + F V+GL Y+ R+
Sbjct: 11225 VS-WTLPKSDGGSPITGYYMERREVT-GKWVRV-NKTPIADLKFRVTGLYEGNTYEFRVF 11281
Query: 744 AHNNAG 749
A N AG
Sbjct: 11282 AENLAG 11287
Score = 102 bits (245), Expect = 6e-21
Identities = 123/491 (25%), Positives = 194/491 (39%), Gaps = 36/491 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVT 337
D P P L+ + ++ S VSW PP G G +VT+ V + VT
Sbjct: 12200 DTPG-PVSDLKVSDVTKTSCHVSWAPPENDG------GSQVTHYIVEKREADRKTWSTVT 12252
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAV 394
++ ++ L Y V A G GV PV P P ++A
Sbjct: 12253 PEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEATE 12312
Query: 395 SSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
++N ++WLPP G + GY + E + T ++ +L + +
Sbjct: 12313 MTKNSATLAWLPPLRDGGAKIDGYIISYREEEQPADRWTEYSVVKDLSLVVTGLKEGKK- 12371
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFSRNIVTPWKENISLSCNKVGVP 511
++F V+A +G V + +P +I + + K+ + + + G P
Sbjct: 12372 -YKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKK-LRIEAHVYGKP 12429
Query: 512 APATTWTM--NGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
P W + V S L + S L I DSG Y+ + EN G D V
Sbjct: 12430 HPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKV 12489
Query: 569 ---EVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVI-NYKREHGDWEELQVE 623
+ PPQPP + D AD+ L W DGGS I Y++ GDW
Sbjct: 12490 VVMDAPGPPQPP-FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 12548
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC---DIVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A NR G P +V + G VP +PK++++ +N
Sbjct: 12549 VTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-VPSEPKNARVTKVN 12607
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS-VQATERVFSVSGLTPAAHY 738
+ V W DGG I+ ++IE +E + W +++ V++TE + +GL Y
Sbjct: 12608 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTE--YPCAGLVEGLEY 12665
Query: 739 QLRITAHNNAG 749
RI A N AG
Sbjct: 12666 SFRIYALNKAG 12676
Score = 102 bits (245), Expect = 6e-21
Identities = 155/634 (24%), Positives = 248/634 (39%), Gaps = 64/634 (10%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
++ EN+ G+ V+V + P GP + ++ +S + V+W PP D +ILG
Sbjct: 23710 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRS---VRVSWRPPADD-GGADILG 23765
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN- 263
Y + +E+ P A YT+ + GT+ + GL+++ Y V A N
Sbjct: 23766 YILERREV-----------PKAAWYTIDS-RVRGTS---LVVKGLKENVEYHFRVSAENQ 23810
Query: 264 ---SRXXXXXXXXXXXXXME--DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
S+ + + PS PP L ++ SV +SW P G + +
Sbjct: 23811 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSLSWSRPKDDGGSRVTGY 23867
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPV 375
Y TD + QI+ T++GL Y + A G + PV
Sbjct: 23868 YIERKETSTDKVVRHNKT--QITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 23925
Query: 376 YCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK 434
C D PS P +++ S++ + + W P G ++GY + D + ++K
Sbjct: 23926 VCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 23985
Query: 435 RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATR----VVTVLPSDSVPARITSF 489
+ T AT ++F V A G R + T L S P I
Sbjct: 23986 ERIKDKQF---TIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKE 24041
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSA 546
+++ T E LSC VG P P W G L + + +SSDG TLT+ +
Sbjct: 24042 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 24101
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ-PPILAVVDSY----ADSLHLQWSDQGDGGS 601
D G YTC N G E + + ++ PQ P + + Y +L L G
Sbjct: 24102 DEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIG-RPV 24160
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEH----VLPNLWCGTRYQLY-ITAFNRIGTGLPC 656
P + + K E + +E +EH V+ N+ T Y + N GT
Sbjct: 24161 PAMTWFHGQKLLQNS-ENITIE--NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI 24217
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRL 715
V K P P + + N+ ++ W DGG I +V+E E + +W+L
Sbjct: 24218 LDVEIQDKPDKPTGPIVIEALLKNSAVIS-WKPPADDGGSWITNYVVEKCEAKEGAEWQL 24276
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
VS+++ T + LT A Y R++A N G
Sbjct: 24277 VSSAISVT--TCRIVNLTENAGYYFRVSAQNTFG 24308
Score = 101 bits (241), Expect = 2e-20
Identities = 124/508 (24%), Positives = 191/508 (37%), Gaps = 54/508 (10%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY----RVTYAPVTDWYGNEDAVTKQIS 341
PPG + A + S+ VSW PP G + I GY R +P +
Sbjct: 9104 PPGKPKVLARTKGSMLVSWTPPLDNGGSPIT-GYWLEKREEGSPYWSRVSRAPITKVGLK 9162
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRN 398
G+ + L Y A AAG G + P D P P+ + +++
Sbjct: 9163 GVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKS 9222
Query: 399 KILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTH--KRMLSPSTLSHETSRSPPRAT- 454
I + W PP+ G + GY + M +EEGT KR+ P L P
Sbjct: 9223 SISLGWKPPAKDGGSPIKGYIVEM------QEEGTTDWKRVNEPDKLITTCECVVPNLKE 9276
Query: 455 ---HQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF-----SRNIVTPWKENISLSCN 506
++F V A GE E + +P+ + F +V I +
Sbjct: 9277 LRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAV 9336
Query: 507 KVGVPAPATTWTMNGVGL-----------ESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
G P P ++W +G E + + + I + + +G Y+ +
Sbjct: 9337 IKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITA 9396
Query: 556 ENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE 613
+N G+ V+V P PP L V D S L W DGG I GYVI +
Sbjct: 9397 KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI 9456
Query: 614 HGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT------KGT 666
G W ++ + G++ V+P+L +Y + A NR G G P + + T
Sbjct: 9457 DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD 9516
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEY-----REMSQPQWRLVSNSVQ 721
P+K K +IT NT ++ W DGG + ++++E + WR N
Sbjct: 9517 PPIKLKIG-LITKNTVHLS-WKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWR-QCNKRD 9573
Query: 722 ATERVFSVSGLTPAAHYQLRITAHNNAG 749
E F+V L Y+ R+ A N AG
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAG 9601
Score = 100 bits (240), Expect = 2e-20
Identities = 115/432 (26%), Positives = 174/432 (40%), Gaps = 31/432 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
++GL Y V A G G V P+ P++P + R+ I + W
Sbjct: 8759 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERQRSTITLDW 8818
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
P S G + GY + + E +KR L P+T S ++F V A
Sbjct: 8819 KEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR-LCPTT-SFLVENLDEHQMYEFRVKAVN 8876
Query: 464 RLGEGEATRVVTV-LPSDSVPA----RITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
+GE E + + V + D VP R++ I E + + + G+P P W+
Sbjct: 8877 EIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWS 8936
Query: 519 MNGVGLESTL------RKNVS-SDGTLTISMTQSA--DSGNYTCSVENIHGRDEVTYTVE 569
N +E ++ VS S+ +S+ ++ D G YT + N G VE
Sbjct: 8937 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVE 8996
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYK---REHGDWEELQVEA 624
V P PP LAV D A+S +L W D GGS I YVI+ + R+ +WEE+ A
Sbjct: 8997 VYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTA 9056
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L +Y+ + A N+ G C D V +P P +++
Sbjct: 9057 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKG 9116
Query: 683 TVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS----VQATERVFSVSGLTPAAH 737
++ V W +GG I + +E RE P W VS + V F+V L
Sbjct: 9117 SMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVK 9176
Query: 738 YQLRITAHNNAG 749
YQ R A N AG
Sbjct: 9177 YQFRAMAINAAG 9188
Score = 100 bits (240), Expect = 2e-20
Identities = 152/646 (23%), Positives = 251/646 (38%), Gaps = 54/646 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS SV++ S + + A+N G+ + V+V P GP V + ++ +
Sbjct: 16102 TSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP---VVISGVTAEKCT 16158
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP +D +I+ Y V +E S V TV A ++
Sbjct: 16159 LAWKPPLQD-GGSDIINYIVERRE---------------TSRLVWTVVDANVQTLSCKVT 16202
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWE 305
L + Y + A N VP P A + ++ S+ V WE
Sbjct: 16203 KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK-APEVTTVTKDSMIVVWE 16261
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + + I L ++GL +Y V A A
Sbjct: 16262 RPASDGGSEIL-GY-VLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENA 16319
Query: 366 AGDGVRAAP-VYCHTEEDV--PSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYM 421
AG + P Y + + P P + K +R+ + +SW P G + GY +
Sbjct: 16320 AGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEK 16379
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVV-TV 476
+ G E T M +P T ++T+ + + + F + A + G GE V +
Sbjct: 16380 CDVNVG--EWT---MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPI 16434
Query: 477 LPSDSVPARITSFS---RNIVTPWKE-NISLSCNKVGVPAPATTW-TMNGVGLESTLRKN 531
+ + + A R I+ ++ L G P P W ++G ++ +
Sbjct: 16435 IVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV 16494
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLH 590
SS +L + DSG YT ++EN G TV V P PP+ L V + DS+
Sbjct: 16495 TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVS 16554
Query: 591 LQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
+ W DGGS I Y++ KRE + + + + L G Y +TA
Sbjct: 16555 ITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 16613
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQM--ITLNTTTVTVWLDSWGDGGCGILYFVIEY 705
N G GLP VP P + +T N+ +++ W DGG I+ +++E
Sbjct: 16614 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS-WTKPEHDGGSKIIQYIVEM 16672
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+ +W + V++ + V ++ LT Y R+ A N G +
Sbjct: 16673 QAKHSEKWSECAR-VKSLQAV--ITNLTQGEEYLFRVVAVNEKGRS 16715
Score = 99.1 bits (236), Expect = 8e-20
Identities = 148/652 (22%), Positives = 258/652 (39%), Gaps = 58/652 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T+ +V++ S + EN G S V V +GP + V + S+ +
Sbjct: 22206 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP---IEVSSVSAESCV 22262
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
++W P +D I Y V +E + + L+ S R++ ++
Sbjct: 22263 LSWGEP-KDGGGTEITNYIVEKRESGTTAWQLVNSS---------------VKRTQIKVT 22306
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL---QCNALSSQSVRVSW 304
L K+ Y+ V + N + + P +PP A + +S+ ++ + W
Sbjct: 22307 HLTKYMEYSFRVSSENR--FGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRW 22364
Query: 305 EPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTL-SGLR-RYTNYSVTV 360
E P G + I+ GY V W + + T L GL ++ Y++
Sbjct: 22365 EEPYHDGGSKII-GYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL 419
+ A + R P+ D P P + +R+ + + W P+ G +VGY +
Sbjct: 22424 AGVSKASEASR--PIMAQNPVDAPGRP---EVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478
Query: 420 Y---MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE----GEATR 472
+S + DGR + ++S + + + T++F V A G E+T
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFT--VTALSEGDTYEFRVLAKNAAGVISKGSESTG 22536
Query: 473 VVTVLPSDSVP-ARITS-FSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLR 529
VT + P A + + ++VT ++ L G P P WT L+ +
Sbjct: 22537 PVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 22596
Query: 530 KNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSY 585
++ G T I +DSG YT +V+N G V+ V+V P P L V
Sbjct: 22597 VSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVT 22656
Query: 586 ADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQL 642
+ L WS Q DGG+ I Y++ +RE +W ++ E T +V+ L Y
Sbjct: 22657 QEKCTLAWSLPQEDGGAEITHYIVE-RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIF 22715
Query: 643 YITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
+ A N+ G G+P + + A T+P P + + + + W DGG I
Sbjct: 22716 RVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEIS 22775
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
++++ RE +W V+ + V+ L YQ R+TA N AG++
Sbjct: 22776 NYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNS 22827
Score = 98.7 bits (235), Expect = 1e-19
Identities = 146/663 (22%), Positives = 262/663 (39%), Gaps = 59/663 (8%)
Query: 118 PQKVIVPGSVTSAS--VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ+ + + S+S ++N Q + ++A+N G+ + + V V P G P
Sbjct: 10069 PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFL 10127
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
S +L TW P+ D I Y + +E + + + +YTV
Sbjct: 10128 AHNLTNESCKL--TWFSPEDD-GGSPITNYVIEKRESDRRAWTPV-------TYTV---- 10173
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCN 293
R T+ GL + AY + A NS + + ++P P L+
Sbjct: 10174 ----TRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 10229
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
++ +V ++W PP G + I+ + T+ + + T+ GL+
Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF--HKVTNDNLLSRKYTVKGLKEG 10287
Query: 354 TNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAVSSR--NKILVSWLPPS 408
Y V A G G + P+ C E P+ D + ++ R ++
Sbjct: 10288 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSG 10347
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
P + + V+ED R TH + +P+TL+ E ++ + ++ V G
Sbjct: 10348 KPKPKVSWFKDEADVLEDDR---THIKT-TPATLALEKIKAKRSDSGKYCVVVENSTGSR 10403
Query: 469 EATRVVTVLPSDSVPARITSFSR----NIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
+ V V+ P SF +V WK + +K+ V +
Sbjct: 10404 KGFCQVNVVDHPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 10463
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE--VTYTVEVK----VPPQPPI 578
T + S+ T +S + EN++G + V+ +++ K VP P
Sbjct: 10464 PVT---SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQ 10520
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD--WEELQVEA--GTSEHVLPNL 634
V + DS + W+ DGG PI Y++ KRE W + + ++ +P+L
Sbjct: 10521 PIVTEVTKDSALVTWNKPHDGGKPITNYILE-KRETMSKRWARVTKDPIHPYTKFRVPDL 10579
Query: 635 WCGTRYQLYITAFNRIGTG---LPCDIVHAYTKGTVPVKPKHSQMI--TLNTTTVTVWLD 689
G +Y+ ++A N IG G P V A P P + + I T N+ +T W
Sbjct: 10580 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT-WQP 10638
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA-TERVFSVSGLTPAAHYQLRITAHNNA 748
DGG IL +++EY+++ +WR +++ ++ E + V+GL Y+ R+ A N A
Sbjct: 10639 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 10698
Query: 749 GHA 751
G +
Sbjct: 10699 GES 10701
Score = 97.5 bits (232), Expect = 2e-19
Identities = 125/500 (25%), Positives = 198/500 (39%), Gaps = 38/500 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L+ + ++ S R+SW+ P G + I +GY + + + V
Sbjct: 9413 DVPG-PPKDLKVSDITRGSCRLSWKMPDDDGGDRI-KGYVIEKRTIDGKAWTK--VNPDC 9468
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSR 397
+ L Y V A G G + T D P P +K + ++
Sbjct: 9469 GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITK 9528
Query: 398 NKILVSWLPPSSPNGVLVGYTLYMSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRA 453
N + +SW PP + G V + + + D +E L
Sbjct: 9529 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 9588
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKE--NISLSCNKVGV 510
++F V A G + + TV P D P S +E N+++ GV
Sbjct: 9589 EYEFRVKAVNAAGVSKPS--ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGV 9646
Query: 511 PAPATTW---------TMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
P P TW V ++ + K V D TL I ++ +D+G YT + N G
Sbjct: 9647 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 9706
Query: 561 RDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHG-- 615
+ V P PP+ + AD + L W + DGGS I YVI KRE
Sbjct: 9707 TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE-KREANRK 9765
Query: 616 DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKPKH 673
W + E + +P L G Y I A N+ G G P D + +VP P
Sbjct: 9766 TWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDK 9825
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVS-NSVQA-TERV-FSV 729
+ ++ ++TV W + DGG + + +E ++ + +W+ V+ + ++A T V + V
Sbjct: 9826 PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKV 9885
Query: 730 SGLTPAAHYQLRITAHNNAG 749
+GL + YQ R+ A N AG
Sbjct: 9886 TGLIEGSDYQFRVYAINAAG 9905
Score = 96.7 bits (230), Expect = 4e-19
Identities = 149/717 (20%), Positives = 267/717 (37%), Gaps = 69/717 (9%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVI 122
L +VP +P + V+D T+ ++W +P Y G S + Y+++ K E W V
Sbjct: 23133 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV---VT 23189
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--------TEEVPSGPPQ 174
+ +V +V +L Y RI A+N G SEP + V T T ++ + P +
Sbjct: 23190 LKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK 23249
Query: 175 DVRVEAKSSTELI--VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
+ V A EL+ + PP W ++ G +L + V + + A T+R
Sbjct: 23250 TIHVPAGRPVELVIPIAGRPPPAASW------FFAG-SKLRESERVTVETHTKVAKLTIR 23302
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
T L + + + V + D P P G ++
Sbjct: 23303 ETTIRDTGEYTLELKNVTGTTSETIKV------------------IILDKPGPPTGPIKI 23344
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTKQISGLHTTLSGL 350
+ + + S+ +SWEPP + G L GY V A W ++VT+ + T L+
Sbjct: 23345 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESVTRS-TFKFTRLTEG 23402
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y + V G +++ + C + +P P ++ SR+ + ++W PP
Sbjct: 23403 NEYV-FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 23461
Query: 411 NGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA-THQFWVSASTRLGEG 468
G V GY + + R +K P T++ S ++ V+A G G
Sbjct: 23462 GGSQVTGYIVERKEVRADRWVRVNK---VPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 23518
Query: 469 EATR-VVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGVG 523
+ +R ++ D + + + + ++SL+ ++ G M V
Sbjct: 23519 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD 23578
Query: 524 LESTLRKNVSSDGTLTISMTQSADSGNY-----TCSVENIHGRDEVTYTVEVKVPPQPPI 578
+ N + ++T Y C+ EV TV+V + P
Sbjct: 23579 QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPD 23638
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEH---VLP 632
+ + Y + + ++ PI G + + +E D + + A + H V+
Sbjct: 23639 YELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIK 23698
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWG 692
G + N+ G V P P I + + V+ W
Sbjct: 23699 EADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVS-WRPPAD 23757
Query: 693 DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG IL +++E RE+ + W + + V+ T V V GL Y R++A N G
Sbjct: 23758 DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKGLKENVEYHFRVSAENQFG 23812
Score = 96.3 bits (229), Expect = 5e-19
Identities = 161/715 (22%), Positives = 271/715 (37%), Gaps = 69/715 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P+ P +I ID + +SW P G S I NYIV+ + W + V +
Sbjct: 12498 PQPPFDISDIDADA--CSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV----TK 12551
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP-SQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
TS V L P Y R+ AENR G SEP + P V P++ RV + +
Sbjct: 12552 TSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCI 12611
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
V W+ P D I+GY + +E NS V VR+ E
Sbjct: 12612 FVAWDRPDSD-GGSPIIGYLIERKERNSLLWVK------ANDTLVRSTE--------YPC 12656
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL + Y+ + A N +P PPG + ++ +V + W
Sbjct: 12657 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MPVDPPGKPEVIDVTKSTVSLIWAR 12715
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + I+ GY V + D + + QI T +GL Y A TA
Sbjct: 12716 PKHDGGSKII-GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 12774
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ P T + P I +V+ ++ + V + + G + +S
Sbjct: 12775 VNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 12833
Query: 425 EDGR----EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+DG EG K + + + E + + + ++A G AT + VL
Sbjct: 12834 KDGTLLKPAEGI-KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 12892
Query: 481 SVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
PA + +S + W+ + +++ T + ++ VS+
Sbjct: 12893 GPPASVKINKMYSDRAMLSWEPPLEDGGSEI------TNYIVDKRETSRPNWAQVSATVP 12946
Query: 538 LTISMTQSADSGN---YTCSVENIHGRDEVTYTVEVKV-----PP---QPPILAVVDSYA 586
+T + G+ + EN +G + +T PP PP+++ +
Sbjct: 12947 ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITK-- 13004
Query: 587 DSLHLQWSDQGD-GGSPILGYVINYKREHG-DWEELQVEAGTSEHV-LPNLWCGTRYQLY 643
D + + W D GGSPI GY++ + +W ++ + + L GT Y+
Sbjct: 13005 DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFR 13064
Query: 644 ITAFNRIGTGLPCDIVH-AYTKGT--VPVKPKHSQMITLNTTTVTVWLDSWG----DGGC 696
+TA N+ G G P D AY + P P ++ ++V++ SWG DGG
Sbjct: 13065 VTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSVSL---SWGKPAYDGGS 13121
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
I+ +++E + W + + F V+GL YQ R+ A N G++
Sbjct: 13122 PIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 13176
Score = 94.7 bits (225), Expect = 2e-18
Identities = 119/487 (24%), Positives = 188/487 (38%), Gaps = 34/487 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGL 343
PP ++ +S+ V W P G + ++ GY + W V +
Sbjct: 20175 PPSTPWVTNVTRESITVGWHEPVSNGGSAVV-GYHLEMKDRNSILWQKANKLVIRTTHFK 20233
Query: 344 HTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT+S GL Y V A AAG G + P D P +++ S+N + +
Sbjct: 20234 VTTISAGLI----YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSL 20289
Query: 403 SWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
SW P+ G + GY + + DGR T + + S + ++F V A
Sbjct: 20290 SWQQPAFDGGSKITGYIVERRDLPDGR--WTKASFTNVTETQFTISGLTQNSQYEFRVFA 20347
Query: 462 STRLGE----GEATRVVTVLPSDSVPARITSFSRNIVTPWK--ENISLSCNKVGVPAPAT 515
+G E +T + S P V ++ ++ L G PAP
Sbjct: 20348 RNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTI 20407
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVTYTVEVKV 572
W + L++ V + L + + AD SG Y + N T V++
Sbjct: 20408 EWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMASASATIRVQILD 20467
Query: 573 PPQPP--ILAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKREHGDWEELQVEAGTSEH 629
P PP + A+ + L W DGG+ I Y++ KRE V E
Sbjct: 20468 KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE-KRETSRVVWSMVSEHLEEC 20526
Query: 630 VL--PNLWCGTRYQLYITAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQM--ITLNTTT 683
++ + G Y + A N+ G G P D V A P P ++ IT N+ T
Sbjct: 20527 IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMT 20586
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V VW DGG I + +E R+ W +++ +++ T + V+GLT + YQ R+
Sbjct: 20587 V-VWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ--KVTGLTENSDYQYRV 20643
Query: 743 TAHNNAG 749
A N AG
Sbjct: 20644 CAVNAAG 20650
Score = 93.9 bits (223), Expect = 3e-18
Identities = 134/613 (21%), Positives = 230/613 (37%), Gaps = 52/613 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T +VP P + + + + ++W+PP+ D ++ Y V Q+ ++ +++SG
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDD-GGSPVINYIVEKQDTRKDTWGVVSSG 11160
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV- 282
+++++ + LQK Y V+A N
Sbjct: 11161 ---------------SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFS 11205
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ-IS 341
P PPG ++ + VSW P G + I GY + VT G V K I+
Sbjct: 11206 PPSPPGKPVVTDITENAATVSWTLPKSDGGSPIT-GYYMERREVT---GKWVRVNKTPIA 11261
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
L ++GL Y V A AG + P+ P P + K SR
Sbjct: 11262 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRE 11321
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT--- 454
+ W P S G ++GY V+E + ++ L + + P
Sbjct: 11322 TADLVWTKPLSDGGSPILGY-----VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGN 11376
Query: 455 -HQFWVSASTRLGEGEATRVV-TVLPSDSV---PARITSFSRNIVTPWK-ENISLSCNKV 508
++F + A+ +GEGE + +V+ D + + R+++T + I +
Sbjct: 11377 EYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK 11436
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSD---GTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TWT G L R ++ D L I AD G Y S +N G + +
Sbjct: 11437 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 11496
Query: 566 YTVEVKVPPQP-PILAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKREHGDWEELQVE 623
V V P P L V + ++ + W + D GGS I +++ Y++ + +
Sbjct: 11497 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 11556
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
T + NL Y + A N++G G + + A P +P++ +
Sbjct: 11557 DVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKG 11616
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHY 738
T V + W DGG L + +E R W R+ S++ T + V Y
Sbjct: 11617 KTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETH--YMVDRCVENQIY 11674
Query: 739 QLRITAHNNAGHA 751
+ R+ N G +
Sbjct: 11675 EFRVQTKNEGGES 11687
Score = 92.7 bits (220), Expect = 7e-18
Identities = 117/485 (24%), Positives = 191/485 (39%), Gaps = 28/485 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQI 340
P PP + ++ S+ V W P G + I+ Y V D G K +
Sbjct: 15157 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN-YIVERR---DKAGQRWIKCNKKTL 15212
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA--APVY--CHTEEDVPSAPADIKAAVSS 396
+ L +SGL Y + A AAG + +P Y C T P P + + +S
Sbjct: 15213 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFK-PGPPGNPRVLDTS 15271
Query: 397 RNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
R+ I ++W P G + GY + +++ E+ + +T S+ + +
Sbjct: 15272 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT-SYTITGLTENQEY 15330
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFS--RNIVTPWKE-NISLSCNKVGV 510
+ + A G GE V ++ +P I + R +VT + L G
Sbjct: 15331 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 15390
Query: 511 PAPATTWTMN-GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P P W + G L+ ++ SS L + DSG Y +VEN G V
Sbjct: 15391 PDPEVKWARDHGESLDKASIESASSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVR 15450
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P PP L V + S+ L W DGGS I Y++ KRE + +
Sbjct: 15451 VLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCH 15509
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ + L G Y + A N G GLP + + P+ P ++ + +V+
Sbjct: 15510 KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVS 15569
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG IL +++E + +W + +V+ TE +++GL Y R++A
Sbjct: 15570 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA-TVKVTEA--TITGLIQGEEYSFRVSA 15626
Query: 745 HNNAG 749
N G
Sbjct: 15627 QNEKG 15631
Score = 91.1 bits (216), Expect = 2e-17
Identities = 141/624 (22%), Positives = 237/624 (37%), Gaps = 59/624 (9%)
Query: 148 ENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
EN G+ E + V+V T GPP +V V+ S VTWEPP D I+ Y V
Sbjct: 13272 ENSCGKKEYTIVVKVLDTP----GPPINVTVKEISKDSAYVTWEPPIID-GGSPIINYVV 13326
Query: 208 GFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXX 267
++ S + + S+ V L++ +Y V A N
Sbjct: 13327 QKRDAERKSWSTVTTECSKTSFRV---------------PNLEEGKSYFFRVFAENEYGI 13371
Query: 268 XXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVT 327
P P L+ ++S S + W+ P G + I+ GY V +
Sbjct: 13372 GDPGETRDAVKASQTPG-PVVDLKVRSVSKSSCSIGWKKPHSDGGSRII-GYVVDFLTEE 13429
Query: 328 DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP 387
+ + V K +S L + L Y+ V A G+G + + +DV +
Sbjct: 13430 NKW---QRVMKSLS-LQYSAKDLTEGKEYTFRVSAENENGEGT-PSEITVVARDDVVAPD 13484
Query: 388 ADIKAA-----VSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
D+K ++ N +P V + + ++ + +
Sbjct: 13485 LDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLI 13544
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENIS 502
++ +S ++ ++ G E T + V+ +P F VT +
Sbjct: 13545 VYDCQKSD---AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDE--VTAEAMTLK 13599
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL---TISMTQSADSGNYT--CSVEN 557
+ K + T + + +S K V+ + T +T+ + YT S EN
Sbjct: 13600 WAPPKDDGGSEITNYILEK--RDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAEN 13657
Query: 558 IHGRDEVTYTVEV------KVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINY 610
+G E + + VP PP +VD DS+ L W+D + GGSPI GY + +
Sbjct: 13658 KYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEF 13717
Query: 611 KREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG---LPCDIVHAYTKG 665
K + W+ + + + L G Y+ + A N G G LP + V A
Sbjct: 13718 KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPI 13777
Query: 666 TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATER 725
P KP+ IT N+ T+ +W + DGG + +++E R++ W + +N V E
Sbjct: 13778 DPPGKPEVIN-ITRNSVTL-IWTEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPEC 13834
Query: 726 VFSVSGLTPAAHYQLRITAHNNAG 749
F+V+ L Y+ RI A N AG
Sbjct: 13835 AFTVTDLVEGGKYEFRIRAKNTAG 13858
Score = 85.0 bits (201), Expect = 1e-15
Identities = 144/628 (22%), Positives = 236/628 (37%), Gaps = 65/628 (10%)
Query: 150 RLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGF 209
+L S S+ VT GPPQ++ V+ + WEPP D + Y +
Sbjct: 17599 KLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDK 17657
Query: 210 QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXX 269
+E + ++S S+ V L + A Y V A N
Sbjct: 17658 RESTRKAYANVSSKCSKTSFKVEN---------------LTEGAIYYFRVMAENEFGVGV 17702
Query: 270 XXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW 329
+ PS PPG + +S S + WE P G + +L GY V P
Sbjct: 17703 PVETVDAVKAAEPPS-PPGKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVVEMQPK--- 17757
Query: 330 YGNED-AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPS 385
G E ++ + + ++GL Y V A+ G V PV PS
Sbjct: 17758 -GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPS 17816
Query: 386 APA-----DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPS 440
I+A + +I V P + + V G L + + E T S
Sbjct: 17817 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT-------S 17869
Query: 441 TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL--PSDSV-PARITSFSRN-IVTP 496
T+ H ++ V+A+ G V VL P V P R S + +V
Sbjct: 17870 TVLH-IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 17928
Query: 497 WKENISLS-C---NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
W+ C N + TT T + V +T+ + T+ I+ ++ +
Sbjct: 17929 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVS--ATVART-----TIKITKLKTGTEYQFR 17981
Query: 553 CSVENIHGRDEV--TYTVEVKVP---PQPPILAVVDSYA-DSLHLQWSDQ-GDGGSPILG 605
EN +G+ + V V+ P P PP V S + D + +QW + DGG+ I+G
Sbjct: 17982 IFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIG 18041
Query: 606 YVINYKREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + K ++ W +L + ++ L G Y+ ++A N +G G P + +
Sbjct: 18042 YHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV 18101
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
P + I + VT+ W DGG I +++E +++ +W + ++
Sbjct: 18102 ARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW-MKASFTNV 18160
Query: 723 TERVFSVSGLTPAAHYQLRITAHNNAGH 750
E F+VSGL Y+ R+ A N AG+
Sbjct: 18161 LETEFTVSGLVEDQRYEFRVIARNAAGN 18188
Score = 83.8 bits (198), Expect = 3e-15
Identities = 138/603 (22%), Positives = 226/603 (37%), Gaps = 55/603 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P++++V + ++ ++W P G S I NYIV+ +E+ ST V T
Sbjct: 15455 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST---VATNCHKT 15511
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V LQ SY+ R++AEN G P++ + E P PP + + + + +
Sbjct: 15512 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL-PPGKITLMDVTRNSVSL 15570
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+WE P+ D ILGY V Q S+ A TV+ E T++G
Sbjct: 15571 SWEKPEHD-GGSRILGYIVEMQTKGSDKWATCA--------TVKVTE--------ATITG 15613
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L + Y+ V A N + +D+ P L N + + P
Sbjct: 15614 LIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVP 15673
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GR + P+ +A + + + L T R + V V +AG+
Sbjct: 15674 FIGRPTPAVTWHKDNVPLKQ-TTRVNAESTENNSLLTIKDACREDVGHYV-VKLTNSAGE 15731
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
+ V + P+ P +K + + I +SW PP G + + I + R
Sbjct: 15732 AIETLNVIVLDKPGPPTGP--VKMDEVTADSITLSWGPPKYDGGSSIN-----NYIVEKR 15784
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRAT---HQFWVSASTRLG-------EGEATRVVTVLP 478
+ T + +T++ T ++ T +QF ++A R G E + +P
Sbjct: 15785 DTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP 15844
Query: 479 SDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
+T SR ++ W E IS ++V + N + L L K
Sbjct: 15845 GPPGTPVVTLSSRDSMEVQWNEPISDGGSRV-IGYHLERKERNSI-LWVKLNKTPIPQTK 15902
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVVDSYADSLHL 591
+ + + S ENI G + + E V PP P +V +S+ L
Sbjct: 15903 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVT--RNSVTL 15960
Query: 592 QWSDQG-DGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
QW DGGS I GY++ K G W + H + L RY+ + A N
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 16020
Query: 649 RIG 651
G
Sbjct: 16021 AAG 16023
Score = 83.4 bits (197), Expect = 4e-15
Identities = 143/705 (20%), Positives = 258/705 (36%), Gaps = 52/705 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQKVIVPGS 126
+VP+ P V + + ++W +P+ G PI NYI++ +E + W + I P
Sbjct: 10513 RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP-- 10570
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST-- 184
T V +L Y R+ AEN +G +PS P + ++ + P V EA +T
Sbjct: 10571 YTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCN 10630
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ +TW+PP+ D ILGY V +Q++ A++T + ++
Sbjct: 10631 SVDLTWQPPRHD-GGSKILGYIVEYQKVGDEEW-------RRANHTPES-----CPETKY 10677
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++GL+ Y V A N+ ++D P L N Q ++V
Sbjct: 10678 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVG- 10736
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK---QISGLHTTLSGLRRYTNYSVTVC 361
+R + I++G V + VT + DA TK ++ + + L +R + +
Sbjct: 10737 --DTLR-LSAIIKG--VPFPKVTWKKEDRDAPTKARIDVTPVGSKLE-IRNAAHEDGGIY 10790
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
+ T D P P D++ + ++ ++W P G ++ T Y+
Sbjct: 10791 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI--TNYV 10848
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTVLP 478
D + SH + F V+A + G G E + + L
Sbjct: 10849 VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 10908
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVGLESTLRKNVSS 534
P V K +SL NK G P G + ++ +
Sbjct: 10909 PLHPPGPPKDLHH--VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVT 10966
Query: 535 DGTLTISMTQSADSGNYTCSVENI--HGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQ 592
+ ++ Q + + ENI G + T +E + PP + + + L ++
Sbjct: 10967 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVK 11026
Query: 593 WSDQGDGGSPILGYVINYKREHGDWEELQ------VEAGTSEHVLPNLWCGTR--YQLYI 644
+ I G + + D E++ VE VL C R + I
Sbjct: 11027 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIE 704
T N G+ + P P + +T T++ W DGG ++ +++E
Sbjct: 11087 TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS-WQPPKDDGGSPVINYIVE 11145
Query: 705 YREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + W +VS+ T+ + L Y R+ A N G
Sbjct: 11146 KQDTRKDTWGVVSSGSSKTK--LKIPHLQKGCEYVFRVRAENKIG 11188
Score = 82.2 bits (194), Expect = 9e-15
Identities = 65/247 (26%), Positives = 107/247 (43%), Gaps = 9/247 (3%)
Query: 511 PAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
P W L + + + I + D G Y ++N HG+ E ++V
Sbjct: 6530 PKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV 6589
Query: 571 -KVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKR-EHGDWEELQVEAGTS 627
VP L V +++ + L W + DGGS I+GYV+ + + W A +
Sbjct: 6590 IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC 6649
Query: 628 EHVLPNLW-CGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTT 683
E + L G Y ++A NR+GTG P + V A +K VP P + + +N
Sbjct: 6650 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFG 6709
Query: 684 VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V++ W DGG I +VIE R+ + +W + +V+A + +V+ + Y R+
Sbjct: 6710 VSLTWEPPEYDGGAEITNYVIELRDKTSIRWD-TAMTVRAEDLSATVTDVVEGQEYSFRV 6768
Query: 743 TAHNNAG 749
A N G
Sbjct: 6769 RAQNRIG 6775
Score = 81.8 bits (193), Expect = 1e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 36/308 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
PE P + D Q R++++SW P G + I+ YI++ +E P++ W + +V
Sbjct: 23734 PEGP--LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV----RG 23787
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTT---TEEVPSGPPQDVRVEAK 181
TS V+ L+ YH R+ AEN+ G S+P +PV T E PS PP+ + V K
Sbjct: 23788 TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV-TK 23846
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
SS L +W P+ D + GYY+ +E +++ V + T T
Sbjct: 23847 SSVSL--SWSRPKDD-GGSRVTGYYIERKETSTDKVV-------RHNKTQITT------- 23889
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQS 299
+ T++GL A Y + A N +D P PG L+ ++S S
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 23949
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
V + WE P G IL GY V Y D + + ++I T+ GL T Y
Sbjct: 23950 VTLQWEKPECDGGKEIL-GYWVEYRQSGD-SAWKKSNKERIKDKQFTIGGLLEATEYEFR 24007
Query: 360 VCAFTAAG 367
V A G
Sbjct: 24008 VFAENETG 24015
Score = 81.0 bits (191), Expect = 2e-14
Identities = 122/561 (21%), Positives = 210/561 (37%), Gaps = 45/561 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N+ + + + ++ +SW P G + I NYIV+ +E +T + + T
Sbjct: 18702 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT---ITNNCTKT 18758
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+ ++NLQ SY+ R++A N G P++ + E P P + V+ +T I
Sbjct: 18759 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI- 18817
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
WE P+ D I GY V Q S V+T+E T+SG
Sbjct: 18818 KWEKPESD-GGSKITGYVVEMQTKGSEK--------WSTCTQVKTLE--------ATISG 18860
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L Y V A N + D+ P L + + ++ P
Sbjct: 18861 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 18920
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+GR +R + + + +K ++ L + Y +C +AG
Sbjct: 18921 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE--LCVSNSAGS 18978
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
P+ D P P I+ S + I +SW PP G + + Y+ ++
Sbjct: 18979 --ITVPITI-IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQI--SNYIVEKKETT 19033
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE---GEATRVVTVLP-----SD 480
H + + S + R + +QF V A R G+ E++ VV P
Sbjct: 19034 STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPP 19093
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
P + + ++ W+ ++ ++ V + L S K + +D + +
Sbjct: 19094 GTPKVVHATKSTMLVTWQVPVNDGGSR--VIGYHLEYKERSSILWSKANKILIADTQVKV 19151
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVE---VKVPPQPPILAVVDSYA-DSLHLQWS-D 595
S Y ENI G + + + E + P PP V + S+ L+WS
Sbjct: 19152 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKP 19211
Query: 596 QGDGGSPILGYVINYKREHGD 616
DGG+ I GY++ +RE D
Sbjct: 19212 HYDGGAKITGYIVE-RRELPD 19231
Score = 78.2 bits (184), Expect = 2e-13
Identities = 147/655 (22%), Positives = 236/655 (36%), Gaps = 78/655 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P + D + + ++W P G S I NY+V+ + E W V
Sbjct: 7287 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV----KD 7342
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTEL 186
T+ L P Y R+ AEN G EP Q +T + P GPP + + +
Sbjct: 7343 TNFKATKLIPNKEYIFRVAAENMYGAGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAV 7402
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP-GGASYTVRTVEGAGTARSRTT 245
+TW P D I GY+V + +++ V P +Y V+
Sbjct: 7403 TLTWCEPDDD-GGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVK------------- 7448
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
GL Y V A N ++D P PPG + SVR++
Sbjct: 7449 --GLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLN 7506
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G ++ Y + G ++ V + G+ TT L GL YS V
Sbjct: 7507 WTKPEHDG-GAKIESYVIEMLKT----GTDEWV-RVAEGVPTTQHLLPGLMEGQEYSFRV 7560
Query: 361 CAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
A AG+ + PV C + PS P ++ ++N + W P G +
Sbjct: 7561 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPI-- 7618
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV-TV 476
T Y+ D R +G + + + + F V+A +G+ + T + +V
Sbjct: 7619 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSV 7678
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAP----------ATTWTMNG- 521
L D+ ++ +V K ++ L N G P T W G
Sbjct: 7679 LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGK 7738
Query: 522 -VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-L 579
G + R +GT + A++ V + E+ + PP PP+ L
Sbjct: 7739 TAGPDCNFRVTDVIEGT-EVQFQVRAEN---EAGVGHPSEPTEILSIEDPTSPPSPPLDL 7794
Query: 580 AVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHGD-WEEL------QVEAGTSEHVL 631
V D+ + + W + +GGSPI+GY + + W + ++ E V+
Sbjct: 7795 HVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVV 7854
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV 686
P+ Y L + A N IG P +I ++ V P I L T + V
Sbjct: 7855 PD----KEYVLRVRAVNAIGVSEPSEI----SENVVAKDPDCKPTIDLETHDIIV 7901
Score = 77.4 bits (182), Expect = 3e-13
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 8/142 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N+ V + + ++W P G SPIINY+VQ ++A +SW + V S
Sbjct: 13290 PGPPINVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST----VTTECSK 13345
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS V NL+ SY R+ AEN G +P + + P GP D++V + S +
Sbjct: 13346 TSFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSCS 13404
Query: 188 VTWEPPQRDLWNGNILGYYVGF 209
+ W+ P D I+GY V F
Sbjct: 13405 IGWKKPHSD-GGSRIIGYVVDF 13425
Score = 76.2 bits (179), Expect = 6e-13
Identities = 87/323 (26%), Positives = 130/323 (40%), Gaps = 29/323 (8%)
Query: 76 IRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
+R + + + ISW P Y G I NYIV+ ++ + T V + T+ +
Sbjct: 17915 VRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTT---TWHMVSATVARTTIKITK 17971
Query: 135 LQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
L+ T Y RI AENR G+S P S+ V V + P GPP V + S +++V W
Sbjct: 17972 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP-GPPGTPFVTSISKDQMLVQWHE 18030
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
P D I+GY++ +E NS V + P + +TT GL +
Sbjct: 18031 PVND-GGTKIIGYHLEQKEKNSILWVKLNKTP------------IQDTKFKTT--GLDEG 18075
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y V A N D P PPG + ++ +V + W+ P G
Sbjct: 18076 LEYEFKVSAENIVGIGKPSKVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYDGG 18134
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD---- 368
+ I GY V + D + + T + T+SGL Y V A AAG+
Sbjct: 18135 SKI-TGYIVEKKDLPDGRWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAGNFSEP 18192
Query: 369 GVRAAPVYCHTEEDVPSAPADIK 391
+ + E D P+A D K
Sbjct: 18193 SDSSGAITARDEIDAPNASLDPK 18215
Score = 74.9 bits (176), Expect = 1e-12
Identities = 88/368 (23%), Positives = 142/368 (38%), Gaps = 25/368 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P+ + ++Q TI + W +P + G SPI YI++ + + K + P T
Sbjct: 8798 PTSPERLTYTERQRSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCP--TT 8855
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT-TTEEVPSGPPQDVRVEAKSSTELI 187
S V+NL Y R+ A N +G+SEPS P+ V +EVP P +R+ + T +
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP--PTIKLRLSVRGDTIKV 8913
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
EP ++ G + E + N TV+ P A + A++ ++
Sbjct: 8914 KAGEPVHIP---ADVTGLPMPKIEWSKNETVI--EKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ V A N + D PS PP L + ++S ++W+ P
Sbjct: 8969 KAVREDKGTYTVTASN---RLGSVFRNVHVEVYDRPS-PPRNLAVTDIKAESCYLTWDAP 9024
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I Y + + + VT + L Y V A G
Sbjct: 9025 LDNGGSEITH-YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 9083
Query: 368 --DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSVI 424
D ++ V +P P K ++ +LVSW PP G + GY L
Sbjct: 9084 ISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWL----- 9138
Query: 425 EDGREEGT 432
+ REEG+
Sbjct: 9139 -EKREEGS 9145
Score = 72.5 bits (170), Expect = 8e-12
Identities = 62/259 (23%), Positives = 104/259 (40%), Gaps = 18/259 (6%)
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGT------LTISMTQSADSGNYTCSVENIHGR 561
+G P PA TW L+++ +N++ + T + ++ + +G Y + N+ G
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNS--ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 24213
Query: 562 DEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQGD-GGSPILGYVINY--KREHGD 616
+ VE++ P P +V +S + W D GGS I YV+ +E +
Sbjct: 24214 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 24273
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
W+ + + + NL Y ++A N G P ++ + KP
Sbjct: 24274 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGK 24333
Query: 677 ITLNTTT----VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
T+ T V W DGG I + +E RE Q +W V+ + E VFSV L
Sbjct: 24334 PTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSVKNL 24392
Query: 733 TPAAHYQLRITAHNNAGHA 751
Y+ R+ N G +
Sbjct: 24393 IEGLEYEFRVKCENLGGES 24411
Score = 71.3 bits (167), Expect = 2e-11
Identities = 114/499 (22%), Positives = 192/499 (38%), Gaps = 44/499 (8%)
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE-DAVT 337
++D P P G + AL S +SW+PP G + I Y V + G E V+
Sbjct: 24222 IQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWI-TNYVVEKCEAKE--GAEWQLVS 24278
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVR-AAPVYCHTEEDVPSAPADIKAAV 394
IS + L Y V A G D + ++ V + + P AP
Sbjct: 24279 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 24338
Query: 395 SSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR-- 452
+++ +V+W PP+S G + Y+ + RE+ +K + + ET S
Sbjct: 24339 VTKDSCVVAWKPPASDGGAKI-RNYYL----EKREKKQNKWISVTTEEIRETVFSVKNLI 24393
Query: 453 --ATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFS---RNIVTPWKENISLSCN 506
++F V GE E + + + P VP + F RN+ ++ N +L C
Sbjct: 24394 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 24453
Query: 507 KVGVPAPATTWTMNGV-----GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
G P P W G GL+ +++ L I+ D+ Y N G
Sbjct: 24454 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS 24513
Query: 562 DEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKR------ 612
T ++EV+VP + + ++ ++H + P G VI +++
Sbjct: 24514 VSGTASLEVEVPAKIHLPKTLEGMG-AVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 24572
Query: 613 EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYIT-AFNRIGTGLPCDIVHAYTKGTVPVKP 671
+G ++ + + TS V PN Y+ A NR G + VP P
Sbjct: 24573 NNGHYQVIVTRSFTS-LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV---ADVPDPP 24628
Query: 672 KHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVS 730
+ ++ + +V + W + DGG I +++E + +W V QA E ++V
Sbjct: 24629 RGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG---QARETRYTVI 24685
Query: 731 GLTPAAHYQLRITAHNNAG 749
L YQ R+ A N G
Sbjct: 24686 NLFGKTSYQFRVIAENKFG 24704
Score = 70.5 bits (165), Expect = 3e-11
Identities = 63/210 (30%), Positives = 86/210 (40%), Gaps = 8/210 (3%)
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQ-GDGGSPIL 604
D G Y VEN HG + TV V P PPI V D S+ +W DGGS I+
Sbjct: 8278 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEII 8337
Query: 605 GYVINYKREHGDWEELQVEAGTSEHV---LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y + K + E V T H + L G Y + A NR G G PC
Sbjct: 8338 NYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL 8397
Query: 662 YTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
K P P + + + ++ V + D G IL + +E RE++ W V+ S
Sbjct: 8398 VAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKS 8457
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + +V GL Y R+ A N AG
Sbjct: 8458 LLNALKA-NVDGLLEGLTYVFRVCAENAAG 8486
Score = 69.3 bits (162), Expect = 7e-11
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 6/148 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P+ P V D S ++ + W +P SPI+ Y ++ +E + S K ++ +
Sbjct: 8406 PDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLL--NALK 8463
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTELI 187
A+V L +Y R+ AEN G + S P T + P GPP RV SST +
Sbjct: 8464 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIP-RVTDTSSTTIE 8522
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSN 215
+ WEPP + G I+GY+V Q + +N
Sbjct: 8523 LEWEPPAFN-GGGEIVGYFVDKQLVGTN 8549
Score = 69.3 bits (162), Expect = 7e-11
Identities = 135/600 (22%), Positives = 233/600 (38%), Gaps = 65/600 (10%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+SW P G S I NY+++ +EA ++W + P T ++ L Y RI
Sbjct: 9739 LSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSE---PKECTY-TIPKLLEGHEYVFRI 9794
Query: 146 IAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
+A+N+ G EP S+P VP G P V + + + V WE P+ D +
Sbjct: 9795 MAQNKYGIGEPLDSEPETARNLFSVP-GAPDKPTVSSVTRNSMTVNWEEPEYD-GGSPVT 9852
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
GY++ ++ S + P ++ A T ++GL + + Y V A N
Sbjct: 9853 GYWLEMKDTTSKRWKRVNRDP------IK----AMTLGVSYKVTGLIEGSDYQFRVYAIN 9902
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGA--LQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P PPG + + S + W PP G + + GY V
Sbjct: 9903 AAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKV-TGYIV 9960
Query: 322 TYAP--VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
Y +W +D K++ G ++GL+ Y V A AG G
Sbjct: 9961 EYKEEGKEEWEKGKD---KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIE 10017
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS-----VIEDGREEGT-- 432
+D +P D++ S R++I+V G ++ Y+S + E T
Sbjct: 10018 MKDRLVSP-DLQLDASVRDRIVVH-------AGGVIRIIAYVSGKPPPTVTWNMNERTLP 10069
Query: 433 HKRMLSPSTLSHETSRSPPRATHQ--FWVSASTRLGEGEATRVVTVLPSDSVPARI-TSF 489
+ + + +S + +HQ + + A GE + T +V VL VP + T F
Sbjct: 10070 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL---DVPGPVGTPF 10126
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
+ +T ++ + +P T + + + V+ T + Q G
Sbjct: 10127 LAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQG 10186
Query: 550 N---YTCSVENIHGRDEVTYTVE-------VKVPPQPPILAVVDSYADSLHLQWS-DQGD 598
+ + EN G T E + VP +P L V + +++ L W+ + D
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246
Query: 599 GGSPILGYVINYKREHGDWEELQVEAG---TSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
GGS I+ YV+ R G + +V + ++ + L G Y+ ++A N +G G P
Sbjct: 10247 GGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10305
Score = 68.5 bits (160), Expect = 1e-10
Identities = 86/332 (25%), Positives = 136/332 (40%), Gaps = 36/332 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N D + ++ W P G S IINY ++ K+ + P + + ++V ++
Sbjct: 8305 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTK--PDS-EWIVVTSTLR 8361
Query: 129 SA--SVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSST 184
SV L Y R+ AENR G P S+P+ P P + + VE +S
Sbjct: 8362 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPI-VEDVTSN 8420
Query: 185 ELIVTWEPPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
++V W P+ NG+ ILGY++ +E+NS S +++ A +
Sbjct: 8421 SMLVKWNEPKD---NGSPILGYWLEKREVNSTHW----------SRVNKSLLNA----LK 8463
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVR 301
+ GL + Y V A N+ D P PPG + SS ++
Sbjct: 8464 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIE 8522
Query: 302 VSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
+ WEPP G G + GY V V T+ + K I T+ +R +Y + V
Sbjct: 8523 LEWEPPAFNG-GGEIVGYFVDKQLVGTNKWSR--CTEKMIKVRQYTVKEIREGADYKLRV 8579
Query: 361 CAFTAAGDGV--RAAPVYCHTEEDVPSAPADI 390
A AAG+G PV ++ P+ D+
Sbjct: 8580 SAVNAAGEGPPGETQPVTVAEPQEPPAVELDV 8611
Score = 66.5 bits (155), Expect = 5e-10
Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+ ++V D ++ ++WT+P + G S I NYIV+ E W Q
Sbjct: 24624 VPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ-----AR 24678
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
T +V NL TSY R+IAEN+ G S+PS+P + T T+E
Sbjct: 24679 ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP PKN RV I ++W +P + G SPII Y+++ KE W ++
Sbjct: 12594 VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLV---R 12650
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T L Y RI A N+ G S PS+P + T +P PP V + + +
Sbjct: 12651 STEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA-RMPVDPPGKPEVIDVTKSTV 12709
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP 224
+ W P+ D I+GY+V +L + V + P
Sbjct: 12710 SLIWARPKHD-GGSKIIGYFVEACKLPGDKWVRCNTAP 12746
Score = 64.9 bits (151), Expect = 2e-09
Identities = 72/307 (23%), Positives = 114/307 (37%), Gaps = 27/307 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
VP P + + + + ++WT P G SPI +YI++ +E W + +
Sbjct: 13975 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 14034
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
V + +Q Y R+ A N G+ EP Q V + P GPP+ V +
Sbjct: 14035 VATKLIQG----NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNT 14090
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
V+W+ P D I GY+V +E S V P + R
Sbjct: 14091 ATVSWKRPVDD-GGSEITGYHVERREKKSLRWVRAIKTP--------------VSDLRCK 14135
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
++GLQ+ + Y V A N M+D P PP + +S ++
Sbjct: 14136 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195
Query: 304 WEPPPMRGRNGI-LQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W P G G+ + GY V + V D +D + + L+ Y+ + A
Sbjct: 14196 WGKPHYDG--GLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253
Query: 363 FTAAGDG 369
AG G
Sbjct: 14254 INDAGVG 14260
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/146 (28%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
+ VP P N+ + D + ++W P Y G + I NY+++ ++ W + + V
Sbjct: 6691 YDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTA---MTVR 6747
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVPSGPPQDVRVEAK 181
SA+V ++ Y R+ A+NR+G +PS V+V E PS PP ++ +
Sbjct: 6748 AEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQ 6806
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYV 207
+ + + + WEPP +D ILGY +
Sbjct: 6807 TQSSVQLKWEPPLKD-GGSPILGYII 6831
Score = 64.1 bits (149), Expect = 3e-09
Identities = 100/411 (24%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I ++ + S T+Q W +P Y G S I YIV+ KE PE W I+
Sbjct: 15945 PGRPEAI-IVTRNSVTLQ--WKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIID--- 15998
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R+IA N G SEPS+ +T +EV PP+ + ++ K
Sbjct: 15999 THFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV--DPPR-ISMDPKYKDT 16055
Query: 186 LIV-TWE--PPQRDLWNGNI--LGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
++V E D++ I + + G QEL++ + + I S S +V+ +
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ + V V+ D P P G + + ++++
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVL------------------DRPGPPEGPVVISGVTAEKC 16157
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
++W+PP G + I+ Y V + + DA + +S T L YT +
Sbjct: 16158 TLAWKPPLQDGGSDII-NYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMA 16216
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYT 418
V + G+ + + PV VP AP + +++ ++V W P+S G ++GY
Sbjct: 16217 VNKY-GVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYV 16275
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L E R HKR++ L + ++F VSA G E
Sbjct: 16276 LEKRDKEGIRWTRCHKRLIGELRL--RVTGLIENHDYEFRVSAENAAGLSE 16324
Score = 63.7 bits (148), Expect = 3e-09
Identities = 67/260 (25%), Positives = 111/260 (42%), Gaps = 31/260 (11%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP +N+ V + + ++W +P G S II Y+V+ ++ ++W +
Sbjct: 6592 VPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRA----E 6647
Query: 127 VTSASVQNLQPA-TSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKS 182
+V LQ Y R+ A NR+G EP PV+ + +VP GPP +V + +
Sbjct: 6648 SCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVN 6706
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARS 242
+ +TWEPP+ D I Y + EL +++ + TVR +
Sbjct: 6707 RFGVSLTWEPPEYD-GGAEITNYVI---ELRDKTSI-----RWDTAMTVRAED------L 6751
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV---PSLPPGALQCNALSSQS 299
T++ + + Y+ V+A N + D PS PP L + + S
Sbjct: 6752 SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSS 6810
Query: 300 VRVSWEPPPMRGRNGILQGY 319
V++ WEPP G + IL GY
Sbjct: 6811 VQLKWEPPLKDGGSPIL-GY 6829
Score = 63.3 bits (147), Expect = 5e-09
Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
Query: 572 VPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINY--KREHGDWEELQVEAGTS 627
V P PP I V +S+ + WS DGGS I GY + K+ G ++ L+ +
Sbjct: 20567 VTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDT 20626
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ L + YQ + A N G G P + A P P ++ +++
Sbjct: 20627 RQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSI 20686
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
T+ W DGG + +V+E R+ + +W VS + + VS L P +Y R++
Sbjct: 20687 TLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 20746
Query: 744 AHNNAG 749
A N AG
Sbjct: 20747 AVNCAG 20752
Score = 62.5 bits (145), Expect = 8e-09
Identities = 90/385 (23%), Positives = 145/385 (37%), Gaps = 37/385 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P+ PKN V ++ + W P + G S IINYIV+ ++ A + W +K +
Sbjct: 15158 PDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD--- 15214
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS--QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L Y RI+AEN G S PS P GPP + RV S +
Sbjct: 15215 LRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSS 15274
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ + W P D I GY V L I + P AG + T
Sbjct: 15275 ISIAWNKPIYD-GGSEITGYMVEI-ALPEEDEWQIVTPP------------AGLKATSYT 15320
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL ++ Y + + A NS ED P L + ++R
Sbjct: 15321 ITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCT 15380
Query: 306 P---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
P++GR + + D E A + + + + R+ + +
Sbjct: 15381 LRLFVPIKGRPDPEVKWARDHGESLDKASIESASSYTL----LIVGNVNRFDSGKYILTV 15436
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
++G ++A V D P P D+K ++ + ++W PP +L G + +
Sbjct: 15437 ENSSGS--KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPP-----LLDGGSKIKN 15488
Query: 423 VIEDGREEGTHKRMLSPSTLSHETS 447
I + R E T K + +T H+TS
Sbjct: 15489 YIVEKR-ESTRKAYSTVATNCHKTS 15512
Score = 61.7 bits (143), Expect = 1e-08
Identities = 101/427 (23%), Positives = 151/427 (35%), Gaps = 28/427 (6%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQK 120
I + P P V + + W P Y G I Y ++ KE + K
Sbjct: 11891 IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNK 11950
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRV 178
+P VQNL P Y R+ AEN +G EPS P + ++ P GPP + RV
Sbjct: 11951 SAIPER--RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRV 12008
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
+ + + W P D I+GY V + AS G R A
Sbjct: 12009 VDTTKHSITLGWGKPVYD-GGAPIIGYVV-----EMRPKIADASPDEGWK---RCNAAAQ 12059
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
R T++ L ++ Y V A N +++ L P + +A S +
Sbjct: 12060 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI--LEPPEIDLDA-SMR 12116
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDW--YGNEDAVTKQISGLHTTLSGL--RRYT 354
+ + P+R + R AP W G ++ V K L T++ L T
Sbjct: 12117 KLVIVRAGCPIR----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST 12172
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
+ T A D P +D+K + ++ VSW PP + G
Sbjct: 12173 RDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 12232
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV- 473
V + + D + T + T H T+ P + F V+A G G T V
Sbjct: 12233 VTHYIVEKREADRKTWSTVTPEVK-KTSFHVTNLVPGN-EYYFRVTAVNEYGPGVPTDVP 12290
Query: 474 VTVLPSD 480
VL SD
Sbjct: 12291 KPVLASD 12297
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 4/134 (2%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQK 120
+ + +VP P +V ++ ISW +P + G SPI+ Y V+ KE T K
Sbjct: 14754 VANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSK 14813
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
+VPG++ +S L +Y R+IAEN G+S+PS+P + + P + V +
Sbjct: 14814 ALVPGNIFKSS--GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI 14871
Query: 181 KSSTELIVTWEPPQ 194
T + + W P+
Sbjct: 14872 TRHT-VTLKWAKPE 14884
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P +++V D + +SW P G S + +YIV+ +EA ++W + +V
Sbjct: 12202 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV----KK 12257
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPS-GPPQDVRVEAKSSTE 185
TS V NL P Y+ R+ A N G P+ P V ++ + PP+ + +
Sbjct: 12258 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEATEMTKNS 12317
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W PP RD I GY + ++E
Sbjct: 12318 ATLAWLPPLRD-GGAKIDGYIISYRE 12342
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/171 (29%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSR-TIQISWTQPYA-GNSPIINYIVQYKEAPESW 114
TVD + P+ P VI+ + + ISW P G S I NY+V+ EA E
Sbjct: 24213 TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEG- 24271
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSG 171
+ Q V SVT+ + NL Y+ R+ A+N G S+P S V + + E P G
Sbjct: 24272 -AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP-G 24329
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
P + A + +V W+PP D I YY+ +E N + + +
Sbjct: 24330 APGKPTITAVTKDSCVVAWKPPASD-GGAKIRNYYLEKREKKQNKWISVTT 24379
Score = 60.1 bits (139), Expect = 4e-08
Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P K+I+ D + +++W P + G +PI++Y+++ +EA T V+ +
Sbjct: 7982 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR---TYIPVMSGENK 8038
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ---PVQVTTTEEVPSGPPQDVRVEAKSST 184
S +V++L P Y R+ A N++G E + PV + + P PP DV V ++
Sbjct: 8039 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV-IAQDPKQPPDPPVDVEVHNPTAE 8097
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ +TW+PP D I+GY +
Sbjct: 8098 AMTITWKPPLYD-GGSKIMGYII 8119
Score = 60.1 bits (139), Expect = 4e-08
Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 7/151 (4%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVP 124
+++P P +V+ + ++ +SWT P G SPI Y ++ +E W + I
Sbjct: 9099 YRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITK 9158
Query: 125 GSVTSA--SVQNLQPATSYHLRIIAENRLGQSEPSQPV--QVTTTEEVPSGPPQDVRVEA 180
+ +V L Y R +A N G PS+P +V P GPP V+
Sbjct: 9159 VGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQE 211
K+ + + + W+PP +D I GY V QE
Sbjct: 9219 KTKSSISLGWKPPAKD-GGSPIKGYIVEMQE 9248
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Query: 75 NIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQ 133
N+R D ++ + W P G S I NYIV+ +EA ST + V
Sbjct: 14376 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYST---ATTKCHKCTYKVT 14432
Query: 134 NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
L Y R++AEN G EP++ + E PS PP + + + + + + W P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS-PPDSLNIMDITKSTVSLAWPKP 14491
Query: 194 QRDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
+ D I GY + Q S+ I + G
Sbjct: 14492 KHD-GGSKITGYVIEAQRKGSDQWTHITTVKG 14522
Score = 59.3 bits (137), Expect = 8e-08
Identities = 75/361 (20%), Positives = 139/361 (38%), Gaps = 39/361 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
E P+N+R+ D ++ +SW QP + G S I YIV+ ++ P+ W + + T
Sbjct: 20272 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNV---TET 20328
Query: 129 SASVQNLQPATSYHLRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
++ L + Y R+ A N +G S PS+ V T + GP D+ +E +
Sbjct: 20329 QFTISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYR 20388
Query: 188 VTWEPPQRDLWNGN---ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
R +G + +Y +EL +N+ V + + AS ++ + +
Sbjct: 20389 AGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYEL 20448
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L A+ + VQ + D P P G ++ ++++ + + W
Sbjct: 20449 KLRNAMASASATIRVQ------------------ILDKPGPPGGPIEFKTVTAEKITLLW 20490
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVTKQISGLHTTLSGLRRYTNYSVTVC 361
PP G G ++T+ V + V++ + T + + + Y V
Sbjct: 20491 RPPADDG------GAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVR 20544
Query: 362 AFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYT 418
A G G + + V P P + ++N + V W P + G + GY
Sbjct: 20545 AVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYF 20604
Query: 419 L 419
L
Sbjct: 20605 L 20605
Score = 58.0 bits (134), Expect = 2e-07
Identities = 87/331 (26%), Positives = 117/331 (35%), Gaps = 32/331 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P I + + T+ +W P G S IINYIV+ +E W V
Sbjct: 16143 PEGPVVISGVTAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANV----QT 16196
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S V L Y RI+A N+ G EP S+PV VP P+ V +
Sbjct: 16197 LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDA-PKAPEVTTVTKDS 16255
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+IV WE P D ILGY VL G +T G R R T
Sbjct: 16256 MIVVWERPASD-GGSEILGY------------VLEKRDKEGIRWTRCHKRLIGELRLRVT 16302
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVS 303
GL ++ Y V A N+ D PP + ++ SV +S
Sbjct: 16303 --GLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLS 16360
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W P G I QGY V V I+ + + L Y+ +CA
Sbjct: 16361 WSKPIYDGGCEI-QGYIVEKCDVNVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 16419
Query: 364 TAAGDGVRA---APVYCHTEEDVPSAPADIK 391
AG G A P+ + + P D++
Sbjct: 16420 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLE 16450
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 8/186 (4%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEH 629
+P P I V + + + +QW+ + DGG+ I Y+++ + +E W + + +
Sbjct: 22742 IPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVVYDT 22801
Query: 630 VLP--NLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTV 684
L +L G YQ +TA N G P + + P P +++ ++
Sbjct: 22802 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPSAPRVVDTTKHSI 22861
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W DGG I+ +V+E +E QW V + F+V L Y R+
Sbjct: 22862 SLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVA 22921
Query: 744 AHNNAG 749
A N G
Sbjct: 22922 AVNVKG 22927
Score = 58.0 bits (134), Expect = 2e-07
Identities = 117/551 (21%), Positives = 204/551 (37%), Gaps = 57/551 (10%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+VQ A Y +++ N G + V++ + P+GP + +EA +++W
Sbjct: 24193 NVQRKTHAGKYKVQL--SNVFGTVDAILDVEIQDKPDKPTGP---IVIEALLKNSAVISW 24247
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT--LSG 248
+PP D G+ + YV V GA + + +A S TT +
Sbjct: 24248 KPPADD--GGSWITNYV----------VEKCEAKEGAEWQL-----VSSAISVTTCRIVN 24290
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEP 306
L ++A Y V A N+ ++ P PG A++ S V+W+P
Sbjct: 24291 LTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKP 24350
Query: 307 PPMRGRNGILQGY-RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G I Y W T++I ++ L Y V
Sbjct: 24351 PASDGGAKIRNYYLEKREKKQNKWIS---VTTEEIRETVFSVKNLIEGLEYEFRVKCENL 24407
Query: 366 AGDGVRAAPVYCHT-EEDVPSAPADIKAAVSSRN-----KILVSWLPPSSPNGVLVGYTL 419
G+ + T + DVP K + + N + P ++ Y
Sbjct: 24408 GGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQ 24467
Query: 420 YMSVIEDGRE------EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+I DG + +G + +++ S + + RAT+Q S G A+
Sbjct: 24468 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQ---GGSV---SGTASLE 24521
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
V V +P + + E +S+ G P P TW +++ V
Sbjct: 24522 VEVPAKIHLPKTLEGMGA-VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 24580
Query: 534 SDGTLTISM----TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADS 588
+ T + + D+G Y +N G D+ T ++V P PP + V D+ DS
Sbjct: 24581 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDS 24640
Query: 589 LHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITA 646
++L W++ DGGS I Y++ + W + +A + + + NL+ T YQ + A
Sbjct: 24641 VNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIA 24699
Query: 647 FNRIGTGLPCD 657
N+ G P +
Sbjct: 24700 ENKFGLSKPSE 24710
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P V D +SWT P + G SPI Y ++ +E W + P +
Sbjct: 11207 PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK---TPIADL 11263
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L +Y R+ AEN G S+P S P++ + P GPP + +++ KS
Sbjct: 11264 KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK-PPGPPINPKLKDKSRET 11322
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W P D ILGY V Q+
Sbjct: 11323 ADLVWTKPLSD-GGSPILGYVVECQK 11347
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GT 537
++ ARI + R++ E+ SC+ G P P TW G L ++ R V++ T
Sbjct: 26061 TLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKST 26120
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
IS Q++D GNY+ VEN G+ E +T+ ++
Sbjct: 26121 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P N+ DQ ++Q+ W P G SPI+ YI++ +E ++W K +VP
Sbjct: 6795 PSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMK-LVPE-- 6851
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L+ Y R+ AEN+ G S+PS+ + T ++ P D+ K E+I
Sbjct: 6852 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVI 6910
Query: 188 V 188
V
Sbjct: 6911 V 6911
Score = 56.8 bits (131), Expect = 4e-07
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP+ P ++D + ++ ++WT P G SPI Y +++KE K P +
Sbjct: 13678 VPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANK--TPIRM 13735
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEV-PSGPPQDVRVEAKSSTE 185
V L Y R++A N G +PS P + V + + P G P+ + + S T
Sbjct: 13736 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT- 13794
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
+ W P+ D + GY V ++L S S
Sbjct: 13795 --LIWTEPKYD-GGHKLTGYIVEKRDLPSKS 13822
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Query: 69 VPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEA-PESWPSTPQKVIVPG 125
VP P I ++D + ISW P G SP+INYIV+ ++ ++W V+ G
Sbjct: 11106 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW-----GVVSSG 11160
Query: 126 -SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSS 183
S T + +LQ Y R+ AEN++G P + P PP V +
Sbjct: 11161 SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITE 11220
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
V+W P+ D I GYY+ +E+
Sbjct: 11221 NAATVSWTLPKSD-GGSPITGYYMERREV 11248
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP PK+++V D + ++SW P G I Y+++ + ++W KV
Sbjct: 9414 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWT----KVNPDCG 9469
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSST 184
T+ V +L Y R+ AENR G P + +Q TT + P PP +++ +
Sbjct: 9470 STTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKN 9529
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ ++W+PP+ D G+ + +Y+
Sbjct: 9530 TVHLSWKPPKND--GGSPVTHYI 9550
Score = 54.8 bits (126), Expect = 2e-06
Identities = 75/309 (24%), Positives = 118/309 (38%), Gaps = 35/309 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P + V + S +SW P G + I +YIVQ +E +W + +V V
Sbjct: 15061 PEGP--LAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEV----QV 15114
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R++A N+ G EP S+PV + P PP++ V +
Sbjct: 15115 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDPPKNPEVTTITKDS 15173
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W P D I+ Y V ++ +G +T+ R
Sbjct: 15174 MVVCWGHPDSD-GGSEIINYIVERRD---------KAGQRWIKCNKKTLTDL-----RYK 15218
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
+SGL + Y + A N+ D PPG + S S+ ++
Sbjct: 15219 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIA 15278
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT---TLSGLRRYTNYSVTV 360
W P G + I GY V A + +E + +GL T++GL Y + +
Sbjct: 15279 WNKPIYDGGSEI-TGYMVEIALPEE---DEWQIVTPPAGLKATSYTITGLTENQEYKIRI 15334
Query: 361 CAFTAAGDG 369
A + G G
Sbjct: 15335 YAMNSEGLG 15343
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 5/149 (3%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIV 123
L + P P V + +I + W +P + G S ++ Y ++ K+ K+++
Sbjct: 20168 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 20227
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
T V + Y R+ AEN G +PS P + + PP++VR+ S
Sbjct: 20228 --RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDA-CEPPRNVRITDISK 20284
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
+ ++W+ P D I GY V ++L
Sbjct: 20285 NSVSLSWQQPAFD-GGSKITGYIVERRDL 20312
Score = 54.4 bits (125), Expect = 2e-06
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
Query: 573 PPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVL 631
PP P +V D ++S+ ++W++ D GSPILGY + KRE +V +
Sbjct: 8405 PPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLE-KREVNSTHWSRVNKSLLNALK 8463
Query: 632 PN---LWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
N L G Y + A N G G P D A+ + P P T +TT
Sbjct: 8464 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIEL 8523
Query: 686 VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W +GG I+ + ++ + + +W + + R ++V + A Y+LR++A
Sbjct: 8524 EWEPPAFNGGGEIVGYFVDKQLVGTNKWSRCTEKM-IKVRQYTVKEIREGADYKLRVSAV 8582
Query: 746 NNAG 749
N AG
Sbjct: 8583 NAAG 8586
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N +V D ++ ++W++P Y G +P+ Y+V+ KEA + W + + G
Sbjct: 18506 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK- 18564
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQ 174
+V L+ T Y+ RI A N G EP+ P V E + PP+
Sbjct: 18565 -QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIE--PPE 18609
Score = 52.4 bits (120), Expect = 9e-06
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWP--STPQKVIVPG 125
P P +V D ++ +SW +P Y G SPII Y+V+ K A ++W + PQ +
Sbjct: 13092 PAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL---- 13147
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V L T Y R+ A N++G S+PS
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 70 PEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
P +P I+ + + + + W P G S I NYI++ +++ + W + V
Sbjct: 13579 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV----Q 13634
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSE--PSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T+ V L Y R+ AEN+ G E S+P+ +VP PP V+ + +
Sbjct: 13635 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 13694
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNS 214
+ +TW P++ I GY++ F+E NS
Sbjct: 13695 -VSLTWTDPKK-TGGSPITGYHLEFKERNS 13722
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 11/152 (7%)
Query: 67 HQVPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIV 123
H +P P I+ + S + SW P G PI NY+V+ ++ + W VI
Sbjct: 14659 HDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR 14718
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENR--LGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T+ L Y R+ A+NR +G S + +VP GPP +V A
Sbjct: 14719 ----TTYKATRLTTGLEYQFRVKAQNRYGVGPGITSAWIVANYPFKVP-GPPGTPQVTAV 14773
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELN 213
+ + ++W P D ILGY+V +E N
Sbjct: 14774 TKDSMTISWHEPLSD-GGSPILGYHVERKERN 14804
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQ 119
+ + + VP+ P + +I ++W +P + G S I YI++ +E + W
Sbjct: 21647 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 21706
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVR 177
K P S T V L Y ++AEN G S ++ E P GPP V+
Sbjct: 21707 KR--PISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 21764
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
V S T + + W P D I+GY +
Sbjct: 21765 VTDTSKTTVSLEWSKPVFD-GGMEIIGYII 21793
Score = 51.6 bits (118), Expect = 2e-05
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 6/140 (4%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ P +++V + ++ I+W P G +PI NYIV+ +EA T V
Sbjct: 23038 YDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAFKT---VTTKC 23094
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T + L T ++ R++ EN G EP + EVP P + V+ ST
Sbjct: 23095 SKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST- 23153
Query: 186 LIVTWEPPQRDLWNGNILGY 205
+ + WE P D + GY
Sbjct: 23154 VTLAWEKPLYD-GGSRLTGY 23172
Score = 51.2 bits (117), Expect = 2e-05
Identities = 99/450 (22%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ PK V ++ + W +P + G S I+ Y+++ ++ W +++I G
Sbjct: 16239 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI--GE 16296
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP--VQVTTTEEVPSGPPQDVRVEAKSST 184
+ V L Y R+ AEN G SEPS P Q GPP + +V + +
Sbjct: 16297 LR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 16355
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ ++W P D I GY V ++N + + P G + T VE
Sbjct: 16356 SVFLSWSKPIYD-GGCEIQGYIVEKCDVNVGEWTM-CTPPTGINKTNIEVEKL------- 16406
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L+KH Y + A N +E+ P L ++R
Sbjct: 16407 ----LEKH-EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGG 16461
Query: 305 EP---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVC 361
P++GR V + V + + S L + RY + T+
Sbjct: 16462 SLRLFVPIKGR----PTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 16517
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
++ G ++A V D PS P ++K +++ + ++W PP +L G +
Sbjct: 16518 LENSS--GTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPP-----LLDGGSKIK 16569
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVVTVL 477
+ I + R E T K + T H+ S + ++ F V+A G G + +
Sbjct: 16570 NYIVEKR-EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPI 16628
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNK 507
VP + + VT + ++SLS K
Sbjct: 16629 KVAEVPQPPGKITVDDVT--RNSVSLSWTK 16656
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P + ++ ++ + W +P G I+ Y V+Y+++ +S W + ++ I
Sbjct: 23934 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQF 23993
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T + L AT Y R+ AEN G S P + T ++ SG +R E K T
Sbjct: 23994 T---IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVT 24046
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
Q P+ P ++ V + + + I+W P Y G S I+ YI++ + E W + +VP
Sbjct: 8081 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEH-LVP- 8138
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR--VEAKSS 183
+ + + + L+ Y R+ AEN G SEPS+ T + P +R +E K
Sbjct: 8139 -ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRG 8197
Query: 184 TEL 186
E+
Sbjct: 8198 DEI 8200
Score = 49.6 bits (113), Expect = 6e-05
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T V N+ S + EN G V+V T GPPQD++V+ + T
Sbjct: 15415 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQDLKVKEVTKTS 15470
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP D I Y V +E + +A+ S+ V
Sbjct: 15471 VTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKV-------------- 15515
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
LQ+ +Y V A N + P LPPG + ++ SV +SWE
Sbjct: 15516 -DQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERP-LPPGKITLMDVTRNSVSLSWE 15573
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + ++ A + T++GL + YS V A
Sbjct: 15574 KPEHDGGSRIL-GYIV---EMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNE 15629
Query: 366 AG 367
G
Sbjct: 15630 KG 15631
Score = 49.6 bits (113), Expect = 6e-05
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 10/171 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
++ P P V ++ ++W +P G + I YI++ ++ W +K +
Sbjct: 18402 YKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD 18461
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEV-PSGPPQDVRVEAKS 182
V L SY R+ AEN G EPS+P V + + P GPP + +V S
Sbjct: 18462 ---LRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 18518
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSN--STVLIASGPGGASYTV 231
+ + + W P D + GY V +E ++ +T +G G +TV
Sbjct: 18519 RSSVSLAWSKPIYD-GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP+ P I V D ++ +SWT+P + G S II YIV+ + + E W + +
Sbjct: 16632 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP 156
+T NL Y R++A N G+S+P
Sbjct: 16692 VIT-----NLTQGEEYLFRVVAVNEKGRSDP 16717
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 8/143 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
+P PK++ V + ++ + W +P + G S II YIV+ ++ W ++ I
Sbjct: 17321 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD-- 17378
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVTTTEEV-PSGPPQDVRVEAKSST 184
V L Y R+ AEN G EPS V + V GPP + + +
Sbjct: 17379 -LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKN 17437
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ + W P D ILGY V
Sbjct: 17438 SITLAWGKPIYD-GGSEILGYVV 17459
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 9/106 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+N++ D+ + +I ++W P G S I YIV+ + W + + P +
Sbjct: 7090 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE----PVA 7145
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVP 169
T V L+ Y R+ NR G S+PS+P +Q T+E P
Sbjct: 7146 ETKMEVTGLEEGKWYAYRVKTLNRQGASKPSRPTEEIQAVDTQEAP 7191
Score = 47.6 bits (108), Expect = 2e-04
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 13/145 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIV-P 124
++P P + + S + ++W P Y G S + + V+ KE W QKV P
Sbjct: 21258 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILW----QKVNTSP 21313
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT--TTEEVPSGPPQDVRVEAKS 182
S L Y R+ AEN G S PS P + T + P G P + V ++
Sbjct: 21314 ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET 21373
Query: 183 STELIVTWEPPQRDLWNGNILGYYV 207
T + W PP RD I+GY +
Sbjct: 21374 IT---LKWNPPLRD-GGSKIVGYSI 21394
Score = 47.2 bits (107), Expect = 3e-04
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWP--STPQKVIVPG 125
P P V D+ +I + W P G SPI YIV+ +E W + P K+I
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLI--- 9264
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
+ V NL+ Y R+ A N G+SEPS TT E+P+ Q+
Sbjct: 9265 TTCECVVPNLKELRKYRFRVKAVNEAGESEPSD-----TTGEIPATDIQE 9309
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 469 EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL 528
E RV + P + S +N+ E+++L C+ G P+P TW +ES++
Sbjct: 882 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 941
Query: 529 RKNVSSDGTLTISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKV 572
++ + M + A DSG +TCS N G + + V+V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPGS 126
VPE P+++ V + T+ ++W P Y G S IINY+++ + E + ++
Sbjct: 10219 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10278
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V+ L+ +Y R+ A N +GQ +PS
Sbjct: 10279 YT---VKGLKEGDTYEYRVSAVNIVGQGKPS 10306
Score = 46.8 bits (106), Expect = 4e-04
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRII 146
I W +P G SP+I Y ++ KE + K I+ T QNL+ Y R+
Sbjct: 16944 IQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD--TQFKAQNLEEGIEYEFRVY 17001
Query: 147 AENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
AEN +G + S+ + + P G P+ + V+ E+ + W P D I G
Sbjct: 17002 AENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYD-GGSMITG 17057
Query: 205 YYVGFQEL 212
Y V ++L
Sbjct: 17058 YIVEKRDL 17065
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 85 TIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T+ + W +P Y G I +YIV+ ++ P W I+ T V L +Y
Sbjct: 14875 TVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFT---VSGLTEDAAYE 14931
Query: 143 LRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
R+IA+N G S PS+P T + P V V+ K + L
Sbjct: 14932 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 14976
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P +P+ + I + S T+ W++P A G S I Y ++ ++ W ++ I
Sbjct: 20572 PGIPE-VTKITKNSMTVV--WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRD--- 20625
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTE 185
T V L + Y R+ A N GQ S+P + + P GPP +R+ + +
Sbjct: 20626 TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSS 20685
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ + W P D + GY V ++
Sbjct: 20686 ITLGWSKPVYD-GGSAVTGYVVEIRQ 20710
Score = 43.2 bits (97), Expect = 0.005
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 79 IDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
ID TI + W P G S I+ Y ++ ++ E W + S +V L P
Sbjct: 21367 IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SECQYTVTGLSP 21423
Query: 138 ATSYHLRIIAENRLGQ-SEPSQP--VQVTTTEEVP 169
Y RIIA N +G S PSQ + +T E VP
Sbjct: 21424 GDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP 21458
Score = 42.3 bits (95), Expect = 0.009
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 13/219 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
+SS V W+PP G I Q Y + + + T G TT++ L
Sbjct: 11811 VSSDRCTVCWDPPEDDGGCEI-QNYILEKCETKRMVWSTYSATVLTPG--TTVTRLIEGN 11867
Query: 355 NYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y V A G G + PV T+ D P P + S+ ++ V W PP G
Sbjct: 11868 EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGG 11927
Query: 413 -VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE-- 469
+ GY L R +K + + + P +QF V A +G GE
Sbjct: 11928 KSITGYFLEKKEKHSTRWVPVNKSAIPERRM--KVQNLLPDHEYQFRVKAENEIGIGEPS 11985
Query: 470 -ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK 507
+R V P T+F +V K +I+L K
Sbjct: 11986 LPSRPVVAKDPIEPPGPPTNF--RVVDTTKHSITLGWGK 12022
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-----KNVSSDG 536
+P +I + +I + ++++C G P P TW+ G + S + +N
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TL I Q D G YT S+ N G D T + ++
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 26924
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
+ P P ++ ++D T+ ++W +P + G S I Y+++ ++ + W V G
Sbjct: 14466 EAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI---TTVKG 14522
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVP 169
V+NL Y +++A N G+S P S+PV V +P
Sbjct: 14523 --LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP 14566
Score = 41.5 bits (93), Expect = 0.016
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENI 558
+LS +G+P P W NGV L + DG +L I T+ D G YTC N
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534
Query: 559 HGR 561
+G+
Sbjct: 3535 YGK 3537
Score = 41.5 bits (93), Expect = 0.016
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
Q P +++V + I W +P++ G S II Y+V + W Q+V+ S
Sbjct: 13385 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW----QRVMKSLS 13440
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
+ S ++L Y R+ AEN G+ PS+ + V ++V + P D++
Sbjct: 13441 L-QYSAKDLTEGKEYTFRVSAENENGEGTPSE-ITVVARDDVVA-PDLDLK 13488
Score = 41.5 bits (93), Expect = 0.016
Identities = 144/720 (20%), Positives = 261/720 (36%), Gaps = 82/720 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE----SWPSTPQKVIVPG 125
+ P V D T+ + W+ P Y G S ++ YI++ K E W ++
Sbjct: 22443 DAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 22502
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLG----QSEPSQPVQVTTTEEVPSGPPQDVR---- 177
T V L +Y R++A+N G SE + PV E P D R
Sbjct: 22503 FFT---VTALSEGDTYEFRVLAKNAAGVISKGSESTGPV-TCRDEYAPPKAELDARLHGD 22558
Query: 178 -VEAKSSTELI----VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
V ++ ++L+ V +P + +W G +EL+ V + A+ ++
Sbjct: 22559 LVTIRAGSDLVLDAAVGGKPEPKIIWT-------KGDKELDLCEKVSLQYTGKRATAVIK 22611
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
+ + + + T+ A +V+V+ +S P P G L
Sbjct: 22612 FCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS------------------PG-PCGKLTV 22652
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
+ ++ + ++W P G I Y V + N V + L ++ L +
Sbjct: 22653 SRVTQEKCTLAWSLPQEDGGAEITH-YIVERRETSRL--NWVIVEGECPTLSYVVTRLIK 22709
Query: 353 YTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y V A G G V + P+ +PS P + + + I++ W P S
Sbjct: 22710 NNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESD 22769
Query: 411 NG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
G + Y + E R +K + T TS +QF V+A G E
Sbjct: 22770 GGNEISNYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLM-EGCDYQFRVTAVNAAGNSE 22828
Query: 470 ATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVG 523
+ + S P+ + +V K +ISL+ K G M
Sbjct: 22829 PSERSNFI-SCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKD 22887
Query: 524 LESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP---P 577
+ R + ++ + T+ + ++ + N+ G E + ++ P + P
Sbjct: 22888 TDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP 22947
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEHVLPNL 634
L + D ++ ++ + G VI + ++ D + T + L +
Sbjct: 22948 DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 23007
Query: 635 WCGTRY---QLYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKHSQMITLNTTTVTVWLD 689
RY + I A N+ G +V Y T G P VK K ++ ++ T+T W
Sbjct: 23008 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE---VSRDSVTIT-WEI 23063
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG I +++E RE + ++ V+ T ++ +SGL + R+ N G
Sbjct: 23064 PTIDGGAPINNYIVEKREAAMRAFKTVTTKCSKT--LYRISGLVEGTMHYFRVLPENIYG 23121
Score = 40.7 bits (91), Expect = 0.028
Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I V + I + WT+P Y G S I YIV+ ++ P+ W ++
Sbjct: 17027 PGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIE--- 17080
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEV 168
T +V L Y R+IA+N G S+PS +T +EV
Sbjct: 17081 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 17123
Score = 39.5 bits (88), Expect = 0.065
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-----SDGTLTISMTQSADSGNYTCS 554
++ C G P P W +GV L + R VS + L ISMT + D+G YT
Sbjct: 1052 SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIV 1111
Query: 555 VENIHG 560
V N HG
Sbjct: 1112 VRNKHG 1117
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
P S P +T V+ + G P P WT +G + + +S D
Sbjct: 26350 PISSKPVIVTGLQDTTVSS-DSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG 26408
Query: 538 ---LTISMTQSADSGNYTCSVENIHG 560
L I T ++DSG YTC+V+N G
Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAG 26434
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 508 VGVPAPATTWTMNGVGLES----TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE 563
VG PAP TW L + T+ N + GT ++ Q DSG Y C EN+ G E
Sbjct: 3599 VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG--E 3656
Query: 564 VTYTVEVKV 572
T E+ V
Sbjct: 3657 STCAAELLV 3665
Score = 37.5 bits (83), Expect = 0.26
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSV 555
+N+ +C G P+P W N + + + ++S +L I +DSG YT
Sbjct: 26652 QNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 26711
Query: 556 ENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS 594
+N G+ T ++ V + P VV + LQ S
Sbjct: 26712 KNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGS 26750
Score = 36.3 bits (80), Expect = 0.61
Identities = 31/142 (21%), Positives = 58/142 (40%), Gaps = 9/142 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP +++ + + ++W+ P G S I +I++ K+A P +
Sbjct: 8699 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQP----IETER 8754
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ--PVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+ + L Y R+IA+N+ G P + P+ P+ P + E + ST
Sbjct: 8755 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERQRST- 8813
Query: 186 LIVTWEPPQRDLWNGNILGYYV 207
+ + W+ P R I GY +
Sbjct: 8814 ITLDWKEP-RSNGGSPIQGYII 8834
Score = 36.3 bits (80), Expect = 0.61
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP +++ + D ++ +SWT+P + G S I Y+V+ K + ++W
Sbjct: 20964 EVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG-----IS 21018
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE 166
V L+ + R+ A+N G S+P +T E
Sbjct: 21019 KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE 21059
Score = 35.9 bits (79), Expect = 0.80
Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 15/151 (9%)
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD-SVPARI 486
+E+GT ++ P+T P + ++ V A R G + ++TV + V
Sbjct: 1462 KEDGTQSLIIVPAT---------PSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMF 1512
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTIS 541
+N+ + + G P P W N + + +GT L I
Sbjct: 1513 VEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1572
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
T S DS YT + N GRD V V+V
Sbjct: 1573 STVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 35.5 bits (78), Expect = 1.1
Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 14/228 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P G + + ++ +SV + WEPP G + + Y + + E V+ +
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV-TNYILLKRETSTAVWTE--VSATV 20127
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ + L Y + A G D + +A V P P+ +R
Sbjct: 20128 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 20187
Query: 399 KILVSWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
I V W P S G +VGY L M + +K ++ T + + ++F
Sbjct: 20188 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI--RTTHFKVTTISAGLIYEF 20245
Query: 458 WVSASTRLGEGEATR-VVTVLPSDSVP----ARITSFSRNIVT-PWKE 499
V A G G+ + VL D+ RIT S+N V+ W++
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQ 20293
Score = 35.5 bits (78), Expect = 1.1
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P + G + I NY ++ +E ++ W S + I T SV+NL Y R+
Sbjct: 24346 VAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI---RETVFSVKNLIEGLEYEFRV 24402
Query: 146 IAENRLGQSEPSQPVQ-VTTTEEVPSGPP 173
EN G+SE S+ + +T +VP P
Sbjct: 24403 KCENLGGESEWSEISEPITPKSDVPIQAP 24431
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT--LTISMTQSADSGNYTCSVE 556
E C G P P W +NG + + R V DG L I +S D+G + E
Sbjct: 1810 ETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAE 1869
Query: 557 NIHGRDEVTYTVEVK 571
N G E +E++
Sbjct: 1870 NPEGVIEHKVKLEIQ 1884
Score = 33.9 bits (74), Expect = 3.2
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVS---SDGT--LTISMTQSADSGNYTCSVENIHGRDE 563
G P P +W +G + ++ V SDG LTI A+SG Y+ N G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 564 VTYTVEVKVPPQPP 577
T + VK PP
Sbjct: 91 STAELLVKAETAPP 104
Score = 33.9 bits (74), Expect = 3.2
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVS-SDGTLTI 540
A I +FS + + + L N G A W +NGV L ++ R VS SD TLTI
Sbjct: 26542 AEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTI 26599
Query: 541 SMTQSADSGNYTC 553
D G TC
Sbjct: 26600 KQASHRDEGILTC 26612
Score = 33.5 bits (73), Expect = 4.3
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+L I TQ D G YTC N +G T T+ V VP
Sbjct: 4393 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 32.7 bits (71), Expect = 7.5
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
D P RIT R+ P +N N P W NGV L ES+ ++ G L
Sbjct: 25874 DHAP-RITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 25932
Query: 539 TISM--TQSADSGNYTCSVENIHGRDEVTYTVEV 570
T+ + + DSG Y N G T++V
Sbjct: 25933 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
>AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine
phosphatase, receptor type, F isoform 2 precursor
variant protein.
Length = 1552
Score = 144 bits (350), Expect = 1e-33
Identities = 104/363 (28%), Positives = 162/363 (44%), Gaps = 23/363 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 167 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 221
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 222 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 281
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 282 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 329
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 330 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 389
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI---SGLHTTLSGLRRYTNYSVTVCAFTA 365
++G ++GY+VTY + + + + + TT+SGL T YSVTV A+T
Sbjct: 390 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTT 449
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
GDG R+ P T VP P + + ++ N L+ W PP G L+GY L +
Sbjct: 450 KGDGARSKPKIVTT--TVPGRPT-MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 506
Query: 426 DGR 428
+ R
Sbjct: 507 EAR 509
Score = 134 bits (324), Expect = 2e-30
Identities = 151/637 (23%), Positives = 250/637 (39%), Gaps = 50/637 (7%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+ ++ + T+ + W P N + Y V Y P+ K + + +V
Sbjct: 73 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLT-TV 131
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW-E 191
+L P +Y LR++A +G PS +QV T + VP+ P D + E +S T + ++W
Sbjct: 132 GSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLL 190
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
PPQ + ++ Y+ E + + +SY TL L+
Sbjct: 191 PPQERIIMYELV-YWAAEDEDQQHKVTFDPT----SSY---------------TLEDLKP 230
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRG 311
Y + A + + PS PP + C ++ S +VRVSW PPP
Sbjct: 231 DTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADS 290
Query: 312 RNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCAFTAAGDG 369
RNG++ Y V Y V D V IS H++ L GL ++T Y V V A T G G
Sbjct: 291 RNGVITQYSVAYEAV-DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 349
Query: 370 VRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSW-LP-PSSPNGVLVGYTLYMSVIED 426
++PV T+EDVPS P ++ + + V W LP PS +G + GY + +E+
Sbjct: 350 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 409
Query: 427 GREEGTHKRMLSPSTLSHETSRS--PPRATHQFWVSASTRLGEGEATR---VVTVLPSDS 481
G G + ET+ S P T+ V+A T G+G ++ V T +P
Sbjct: 410 GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTVPGRP 469
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
T+ + W L +G + +T+ D T++
Sbjct: 470 TMMISTTAMNTALLQWHPPKELPGELLGY---RLQYCRADEARPNTIDFG-KDDQHFTVT 525
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ-----PPILAVVDSYADSLHLQWSDQ 596
+ + + +N G E + E++ P P L V + L W
Sbjct: 526 GLHKGTTYIFRLAAKNRAGLGE-EFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPP 584
Query: 597 --GDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+ I+ Y + + R+ +ELQ + L L T Y + + A+ G+G
Sbjct: 585 VLAERNGRIISYTVVF-RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSG- 642
Query: 655 PCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSW 691
+ + T+PV+ ++ + T L SW
Sbjct: 643 --PLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSW 677
Score = 123 bits (296), Expect = 4e-27
Identities = 134/533 (25%), Positives = 216/533 (40%), Gaps = 33/533 (6%)
Query: 238 GTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSS 297
G A +R ++ GL + YA V A NS E PS PP +Q LS+
Sbjct: 24 GVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSA 83
Query: 298 QSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS 357
++ V WEPP NG+++GYRV Y P + N +GL TT+ L YS
Sbjct: 84 STMLVQWEPP--EEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 141
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ V AFTA GDG + + T++ VP+ PAD +A V S +I +SWL P P ++ Y
Sbjct: 142 LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLP--PQERIIMY 199
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL 477
L ED E+ HK P T S+ P ++F ++A + +G G T +
Sbjct: 200 ELVYWAAED--EDQQHKVTFDP-TSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR 256
Query: 478 PSDSVPAR-------ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK 530
+ S P+ ++ S + W + S N V ++G +
Sbjct: 257 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 316
Query: 531 NVSSDGTL--TISMTQSADSGNYTCSVENIHGRDE---VTYTVEVKVPPQPPILAVVDSY 585
+S + + + + + + + + ++ E V + VP PP V+
Sbjct: 317 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL 376
Query: 586 -ADSLHLQWS--DQGDGGSPILGYVINYKR-EHGDWEELQV-----EAGTSEHVLPNLWC 636
+ ++H+ W I GY + Y R E+G+ L + A E + L
Sbjct: 377 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP 436
Query: 637 GTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGC 696
T Y + + A+ G G T TVP +P T T + W G
Sbjct: 437 ETTYSVTVAAYTTKGDGARSKPKIVTT--TVPGRPTMMISTTAMNTALLQWHPPKELPG- 493
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+L + ++Y + + + ++ F+V+GL Y R+ A N AG
Sbjct: 494 ELLGYRLQYCRADEARPNTI--DFGKDDQHFTVTGLHKGTTYIFRLAAKNRAG 544
Score = 121 bits (291), Expect = 2e-26
Identities = 157/673 (23%), Positives = 265/673 (39%), Gaps = 56/673 (8%)
Query: 99 PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQ 158
P+ Y +QY+ A P + + T S+ L P + Y R++A N +G+ PS+
Sbjct: 2 PVTYYGIQYRAAGTEGPFQEVDGV---ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSE 58
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
V+ T E+ PS PP+ V+ S++ ++V WEPP+ NG + GY V + +
Sbjct: 59 AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEP--NGLVRGYRVYYTPDSRR--- 113
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
P A + T G TT+ L Y++ V A+ +
Sbjct: 114 -----PPNAWHKHNTDAGL-----LTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 163
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK 338
+ VP+ P Q S +++SW PP + I+ Y + Y D + VT
Sbjct: 164 QQGVPA-QPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVYWAAED-EDQQHKVTF 217
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVS-SR 397
+ + TL L+ T Y + A + G GV + T + PSAP VS
Sbjct: 218 DPTSSY-TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGS 276
Query: 398 NKILVSWLPP--SSPNGVLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRAT 454
+ VSW+PP S NGV+ Y++ + DG + G H +S S +
Sbjct: 277 TTVRVSWVPPPADSRNGVITQYSVAYEAV-DGEDRGRHVVDGISREHSSWDLVGLEKWTE 335
Query: 455 HQFWVSASTRLGEGEATRVVTVLPSDSVPA------RITSFSRNIV-TPWKENI-SLSCN 506
++ WV A T +G G + V V + VP+ + + V WK + S
Sbjct: 336 YRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHG 395
Query: 507 KVGVPAPATTWTMNGV--GLESTLRKNVSSDGTLTIS-----MTQSADSGNYTCSVENIH 559
++ NG GL ++ TIS T S YT +
Sbjct: 396 QIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGAR 455
Query: 560 GRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWE 618
+ ++ T VP +P ++ + +L LQW + +LGY + Y R +
Sbjct: 456 SKPKIVTTT---VPGRPTMMISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPN 511
Query: 619 ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMIT 678
+ + L GT Y + A NR G G + + P++ +
Sbjct: 512 TIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTG 571
Query: 679 LNTTTVTVWLDS--WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAA 736
L T+T + D + I+ + + +R+++ Q + N T+ F+++GL P
Sbjct: 572 LTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQ--ELQNI--TTDTRFTLTGLKPDT 627
Query: 737 HYQLRITAHNNAG 749
Y +++ A + G
Sbjct: 628 TYDIKVRAWTSKG 640
Score = 109 bits (262), Expect = 5e-23
Identities = 101/378 (26%), Positives = 156/378 (41%), Gaps = 26/378 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 252 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 309
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 310 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 369
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTV 234
V VE +ST + V W+ P +G I GY V + L + P G ++ V
Sbjct: 370 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-------PRGLP-IIQDV 421
Query: 235 EGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA 294
A TT+SGL Y+V V AY ++ VP P + A
Sbjct: 422 MLA--EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT--TVPGRPTMMISTTA 477
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
++ + + W PP + G L GYR+ Y + N K H T++GL + T
Sbjct: 478 MN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGLHKGT 531
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPN 411
Y + A AG G T ED+PS P ++ + + ++W PP + N
Sbjct: 532 TYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 590
Query: 412 GVLVGYTLYMSVIEDGRE 429
G ++ YT+ I +E
Sbjct: 591 GRIISYTVVFRDINSQQE 608
Score = 86.6 bits (205), Expect = 4e-16
Identities = 87/375 (23%), Positives = 142/375 (37%), Gaps = 32/375 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKV--IVPGSVT 128
P+ + V S + + W P + I Y V Y P + ++
Sbjct: 368 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 427
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++
Sbjct: 428 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT--VPGRPTMMISTTAMNTA--LL 483
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W PP+ G +LGY + + + I G +TV +G
Sbjct: 484 QWHPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TG 526
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L K Y + A N R ED+PS P L L++ + ++W+PP
Sbjct: 527 LHKGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 585
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+ RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G
Sbjct: 586 LAERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGS 641
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIED 426
G + + T + + A + + +L+SW P S + LY SV D
Sbjct: 642 GPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVD 701
Query: 427 GREEGTHKRMLSPST 441
G L P+T
Sbjct: 702 GHSMRKLIADLQPNT 716
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 144 bits (349), Expect = 2e-33
Identities = 133/514 (25%), Positives = 214/514 (41%), Gaps = 36/514 (7%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPST 117
R+ +L P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W
Sbjct: 619 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 678
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDV 176
+ PGSV SA V L P +Y R+IA N +G S PS P + T+ P P DV
Sbjct: 679 SK---YPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 734
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ E + +TW P G L Y V ++ + ++ TV G
Sbjct: 735 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG 783
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
SR + + Y + VQA N ED P P ++ ++
Sbjct: 784 -----SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMN 838
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGL 350
S ++ + W G L+ YR Y + + + + ++ G L +S L
Sbjct: 839 STAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRL 898
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y+NY + + GDG R+ T E VPSAP + + I + W P P
Sbjct: 899 FPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHP 958
Query: 411 NGVLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GE
Sbjct: 959 NGIMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGE 1017
Query: 470 A-TRVVTVLPSDSVP-ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST 527
A T P+++ P A + V S + ATT + +T
Sbjct: 1018 AVTEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTT 1077
Query: 528 L--RKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+ V++ T T + T + +S T S IH
Sbjct: 1078 IATTTTVATTTTTTAAATTTTESPPTTTSGTKIH 1111
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 386 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 440
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 441 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 500
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 501 CVATNILGKAENQVRLEVKDP 521
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 263 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 322
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 323 GSIRHTISVRVKAAP 337
Score = 40.3 bits (90), Expect = 0.037
Identities = 65/294 (22%), Positives = 101/294 (34%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 521 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 579
Query: 541 SMTQSADSGNYTCSVENIHGRD-----------EVTYTVEVKV-----PPQPPILAVVDS 584
D G+YTC +D + T T + P +P L + D
Sbjct: 580 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 639
Query: 585 YADSLHLQWSDQGDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQ 641
S+ L W SPI YV+ ++ + G W + G+ + L YQ
Sbjct: 640 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQ 699
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGC 696
+ A N +G+ P Y P + + T W +++ G
Sbjct: 700 FRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGP 759
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
+ Y V R ++ W N+V + V G TP Y++R+ A N+ G
Sbjct: 760 NLRYIVKWRRRETREAW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 808
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 402
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 143 bits (347), Expect = 3e-33
Identities = 158/698 (22%), Positives = 265/698 (37%), Gaps = 44/698 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P RV+D +I ++WT+P Y G + I+ Y+++ +E + W +
Sbjct: 569 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRN-- 626
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +L+ Y R+ A N G SE S+ + E P ++ + K + +
Sbjct: 627 TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIR 686
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G L V ++ +I G R + + S +
Sbjct: 687 A-----------GASLRLMVS---VSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 732
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ ++ A ++A N + D P P +++ +S SV ++WE P
Sbjct: 733 KVNRYDAGKYTIEAENQ---SGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIP 788
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
+ G + Y V VT + S +SGL T + V G
Sbjct: 789 TIDG-GAPINNYIVEKREAA--MRAFKTVTTKCSKTLYRISGLVEGTMHYFRVLPENIYG 845
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIED 426
G +VP PA ++ +++ + ++W P G L GY L +
Sbjct: 846 IGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL--EACKA 903
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR- 485
G E L P+ L H + + F + A G E VT + +
Sbjct: 904 GTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP 963
Query: 486 ----ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTL 538
T + I P + L G P PA +W G L + R V + L
Sbjct: 964 TIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKL 1023
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS-D 595
TI T D+G YT ++N+ G T V + P PP + + + A S+ + W
Sbjct: 1024 TIRETTIRDTGEYTLELKNVTGTTLETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP 1083
Query: 596 QGDGGSPILGYVINYKREH-GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG- 653
+ DGG+P+ GYV+ + H W + S L G Y + A NR G G
Sbjct: 1084 ELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 1143
Query: 654 -LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP 711
L +++ + +P P+ Q+ ++ +T+ W DGG + +++E +E+
Sbjct: 1144 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD 1203
Query: 712 QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V N V T + +GLT Y+ R+TA N G
Sbjct: 1204 RWVRV-NKVPVTMTRYRSTGLTEGLEYEHRVTAINARG 1240
Score = 112 bits (270), Expect = 6e-24
Identities = 148/604 (24%), Positives = 222/604 (36%), Gaps = 47/604 (7%)
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P ++++ +T + ++WEPP+ D + GY V ++ A PG
Sbjct: 1059 PGPPTGPIKIDEIDATSITISWEPPELD-GGAPLSGYVVEQRD---------AHRPGWLP 1108
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLP 286
+ RS + L + Y V A N + P P
Sbjct: 1109 VS------ESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG-P 1161
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHT 345
P LQ +S + ++W PP G + + GY V V D + + V ++ +
Sbjct: 1162 PETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRADRWVRVNKVPVTMTRYRS 1220
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILV 402
T GL Y V A A G G + P D P P + + ++R + +
Sbjct: 1221 T--GLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 1278
Query: 403 SWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
+W P G V GY + M ++ + E T + + P A ++F V A
Sbjct: 1279 AWSVPEDEGGSKVTGYLIEMQKVD--QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 1336
Query: 462 STRLGEGEATRV---VTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATT 516
G GE V V V P + I I L+ G P P
Sbjct: 1337 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 1396
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
WT G + S T L I DSG Y +EN G+ V V V P
Sbjct: 1397 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 1456
Query: 576 PPI--LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR-EHGDWEELQVEAGTSEHVL 631
P L D S+ + W D GG+ ILGY++ + W + + V+
Sbjct: 1457 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVV 1516
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMITLNTTTVTVWLD 689
L Y ++A N+ G P T T P +P + L+ T +V L
Sbjct: 1517 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL- 1575
Query: 690 SWG----DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
SW DGG + + IE +E S + + N Q T +++V+GL P A YQ RI A
Sbjct: 1576 SWSRPKDDGGSRVTGYYIERKETSTDKV-VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQ 1634
Query: 746 NNAG 749
N+ G
Sbjct: 1635 NDVG 1638
Score = 102 bits (245), Expect = 6e-21
Identities = 155/634 (24%), Positives = 248/634 (39%), Gaps = 64/634 (10%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
++ EN+ G+ V+V + P GP + ++ +S + V+W PP D +ILG
Sbjct: 1434 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRS---VRVSWRPPADD-GGADILG 1489
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN- 263
Y + +E+ P A YT+ + GT+ + GL+++ Y V A N
Sbjct: 1490 YILERREV-----------PKAAWYTIDS-RVRGTS---LVVKGLKENVEYHFRVSAENQ 1534
Query: 264 ---SRXXXXXXXXXXXXXME--DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
S+ + + PS PP L ++ SV +SW P G + +
Sbjct: 1535 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSLSWSRPKDDGGSRVTGY 1591
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPV 375
Y TD + QI+ T++GL Y + A G + PV
Sbjct: 1592 YIERKETSTDKVVRHNKT--QITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 1649
Query: 376 YCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK 434
C D PS P +++ S++ + + W P G ++GY + D + ++K
Sbjct: 1650 VCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 1709
Query: 435 RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATR----VVTVLPSDSVPARITSF 489
+ T AT ++F V A G R + T L S P I
Sbjct: 1710 ERIKDKQF---TIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKE 1765
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSA 546
+++ T E LSC VG P P W G L + + +SSDG TLT+ +
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 1825
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ-PPILAVVDSY----ADSLHLQWSDQGDGGS 601
D G YTC N G E + + ++ PQ P + + Y +L L G
Sbjct: 1826 DEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIG-RPV 1884
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEH----VLPNLWCGTRYQLY-ITAFNRIGTGLPC 656
P + + K E + +E +EH V+ N+ T Y + N GT
Sbjct: 1885 PAMTWFHGQKLLQNS-ENITIE--NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI 1941
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRL 715
V K P P + + N+ ++ W DGG I +V+E E + +W+L
Sbjct: 1942 LDVEIQDKPDKPTGPIVIEALLKNSAVIS-WKPPADDGGSWITNYVVEKCEAKEGAEWQL 2000
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
VS+++ T + LT A Y R++A N G
Sbjct: 2001 VSSAISVT--TCRIVNLTENAGYYFRVSAQNTFG 2032
Score = 97.5 bits (232), Expect = 2e-19
Identities = 119/495 (24%), Positives = 200/495 (40%), Gaps = 34/495 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQ 339
VP P + +S+ ++ + WE P G + I+ GY V W +
Sbjct: 66 VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKII-GYWVEKKERNTILWVKENKVPCLE 124
Query: 340 ISGLHTTL-SGLR-RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ T L GL ++ Y++ + A + R P+ D P P R
Sbjct: 125 CNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR--PIMAQNPVDAPGRPGVTDV---QR 179
Query: 398 NKILVSWLPPSSPNGV-LVGYTLY---MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
+ + + W P+ G +VGY + +S + DGR + ++S + + +
Sbjct: 180 STVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFT--VTALSEGD 237
Query: 454 THQFWVSASTRLGE----GEATRVVTVLPSDSVP-ARITS-FSRNIVTPWK-ENISLSCN 506
T++F V A G E+T VT + P A + + ++VT ++ L
Sbjct: 238 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 297
Query: 507 KVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDE 563
G P P WT L+ + ++ G T I +DSG YT +V+N G
Sbjct: 298 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 357
Query: 564 VTYTVEVKVPPQP-PILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEE 619
V+ V+V P P L V + L WS Q DGG+ I Y++ +RE +W
Sbjct: 358 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVE-RRETSRLNWVI 416
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMI 677
++ E T +V+ L Y + A N+ G G+P + + A T+P P + +
Sbjct: 417 VEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 476
Query: 678 TLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAA 736
+ + W DGG I ++++ RE +W V+ + V+ L
Sbjct: 477 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLMEGC 536
Query: 737 HYQLRITAHNNAGHA 751
YQ R+TA N AG++
Sbjct: 537 DYQFRVTAVNAAGNS 551
Score = 95.9 bits (228), Expect = 7e-19
Identities = 149/717 (20%), Positives = 266/717 (37%), Gaps = 69/717 (9%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVI 122
L +VP +P + V+D T+ ++W +P Y G S + Y+++ K E W V
Sbjct: 857 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV---VT 913
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--------TEEVPSGPPQ 174
+ +V +V +L Y RI A+N G SEP + V T T ++ + P +
Sbjct: 914 LKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK 973
Query: 175 DVRVEAKSSTELI--VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
+ V A EL+ + PP W ++ G +L + V + + A T+R
Sbjct: 974 TIHVPAGRPVELVIPIAGRPPPAASW------FFAG-SKLRESERVTVETHTKVAKLTIR 1026
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
T L + + V + D P P G ++
Sbjct: 1027 ETTIRDTGEYTLELKNVTGTTLETIKV------------------IILDKPGPPTGPIKI 1068
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTKQISGLHTTLSGL 350
+ + + S+ +SWEPP + G L GY V A W ++VT+ + T L+
Sbjct: 1069 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESVTRS-TFKFTRLTEG 1126
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y + V G +++ + C + +P P ++ SR+ + ++W PP
Sbjct: 1127 NEYV-FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 1185
Query: 411 NGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA-THQFWVSASTRLGEG 468
G V GY + + R +K P T++ S ++ V+A G G
Sbjct: 1186 GGSQVTGYIVERKEVRADRWVRVNK---VPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 1242
Query: 469 EATR-VVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGVG 523
+ +R ++ D + + + + ++SL+ ++ G M V
Sbjct: 1243 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD 1302
Query: 524 LESTLRKNVSSDGTLTISMTQSADSGNY-----TCSVENIHGRDEVTYTVEVKVPPQPPI 578
+ N + ++T Y C+ EV TV+V + P
Sbjct: 1303 QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPD 1362
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEH---VLP 632
+ + Y + + ++ PI G + + +E D + + A + H V+
Sbjct: 1363 YELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIK 1422
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWG 692
G + N+ G V P P I + + V+ W
Sbjct: 1423 EADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVS-WRPPAD 1481
Query: 693 DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG IL +++E RE+ + W + + V+ T V V GL Y R++A N G
Sbjct: 1482 DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKGLKENVEYHFRVSAENQFG 1536
Score = 81.8 bits (193), Expect = 1e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 36/308 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
PE P + D Q R++++SW P G + I+ YI++ +E P++ W + +V
Sbjct: 1458 PEGP--LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV----RG 1511
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTT---TEEVPSGPPQDVRVEAK 181
TS V+ L+ YH R+ AEN+ G S+P +PV T E PS PP+ + V K
Sbjct: 1512 TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV-TK 1570
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
SS L +W P+ D + GYY+ +E +++ V + T T
Sbjct: 1571 SSVSL--SWSRPKDD-GGSRVTGYYIERKETSTDKVV-------RHNKTQITT------- 1613
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQS 299
+ T++GL A Y + A N +D P PG L+ ++S S
Sbjct: 1614 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 1673
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
V + WE P G IL GY V Y D + + ++I T+ GL T Y
Sbjct: 1674 VTLQWEKPECDGGKEIL-GYWVEYRQSGD-SAWKKSNKERIKDKQFTIGGLLEATEYEFR 1731
Query: 360 VCAFTAAG 367
V A G
Sbjct: 1732 VFAENETG 1739
Score = 72.5 bits (170), Expect = 8e-12
Identities = 62/259 (23%), Positives = 104/259 (40%), Gaps = 18/259 (6%)
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGT------LTISMTQSADSGNYTCSVENIHGR 561
+G P PA TW L+++ +N++ + T + ++ + +G Y + N+ G
Sbjct: 1880 IGRPVPAMTWFHGQKLLQNS--ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 1937
Query: 562 DEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQGD-GGSPILGYVINY--KREHGD 616
+ VE++ P P +V +S + W D GGS I YV+ +E +
Sbjct: 1938 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 1997
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
W+ + + + NL Y ++A N G P ++ + KP
Sbjct: 1998 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGK 2057
Query: 677 ITLNTTT----VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
T+ T V W DGG I + +E RE Q +W V+ + E VFSV L
Sbjct: 2058 PTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSVKNL 2116
Query: 733 TPAAHYQLRITAHNNAGHA 751
Y+ R+ N G +
Sbjct: 2117 IEGLEYEFRVKCENLGGES 2135
Score = 71.3 bits (167), Expect = 2e-11
Identities = 114/499 (22%), Positives = 192/499 (38%), Gaps = 44/499 (8%)
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE-DAVT 337
++D P P G + AL S +SW+PP G + I Y V + G E V+
Sbjct: 1946 IQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWI-TNYVVEKCEAKE--GAEWQLVS 2002
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVR-AAPVYCHTEEDVPSAPADIKAAV 394
IS + L Y V A G D + ++ V + + P AP
Sbjct: 2003 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 2062
Query: 395 SSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR-- 452
+++ +V+W PP+S G + Y+ + RE+ +K + + ET S
Sbjct: 2063 VTKDSCVVAWKPPASDGGAKI-RNYYL----EKREKKQNKWISVTTEEIRETVFSVKNLI 2117
Query: 453 --ATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFS---RNIVTPWKENISLSCN 506
++F V GE E + + + P VP + F RN+ ++ N +L C
Sbjct: 2118 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 2177
Query: 507 KVGVPAPATTWTMNGV-----GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
G P P W G GL+ +++ L I+ D+ Y N G
Sbjct: 2178 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS 2237
Query: 562 DEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKR------ 612
T ++EV+VP + + ++ ++H + P G VI +++
Sbjct: 2238 VSGTASLEVEVPAKIHLPKTLEGMG-AVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 2296
Query: 613 EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYIT-AFNRIGTGLPCDIVHAYTKGTVPVKP 671
+G ++ + + TS V PN Y+ A NR G + VP P
Sbjct: 2297 NNGHYQVIVTRSFTS-LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV---ADVPDPP 2352
Query: 672 KHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVS 730
+ ++ + +V + W + DGG I +++E + +W V QA E ++V
Sbjct: 2353 RGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG---QARETRYTVI 2409
Query: 731 GLTPAAHYQLRITAHNNAG 749
L YQ R+ A N G
Sbjct: 2410 NLFGKTSYQFRVIAENKFG 2428
Score = 66.5 bits (155), Expect = 5e-10
Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+ ++V D ++ ++WT+P + G S I NYIV+ E W Q
Sbjct: 2348 VPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ-----AR 2402
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
T +V NL TSY R+IAEN+ G S+PS+P + T T+E
Sbjct: 2403 ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 2443
Score = 63.7 bits (148), Expect = 3e-09
Identities = 130/617 (21%), Positives = 230/617 (37%), Gaps = 55/617 (8%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ P +++V + ++ I+W P G +PI NYIV+ +EA T V
Sbjct: 762 YDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAFKT---VTTKC 818
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T + L T ++ R++ EN G EP + EVP P + V+ ST
Sbjct: 819 SKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST- 877
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ + WE P D G+ L YV + + G ++ V T T
Sbjct: 878 VTLAWEKPLYD--GGSRLTGYV------------LEACKAGTERWMKVVTLKPTVLEHTV 923
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
S L + Y ++A N + ++D+ LP + + + +++ V
Sbjct: 924 TS-LNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP--TIDLSTMPQKTIHVPAG 980
Query: 306 PP-----PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
P P+ GR + + + + +++ L + +R Y++ +
Sbjct: 981 RPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 1040
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL 419
T G + V + P+ P IK I +SW PP G L GY +
Sbjct: 1041 KNVT--GTTLETIKVIILDKPGPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVV 1096
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE--ATRVVTVL 477
D G S + + + +R + F V+A+ R G G + V+
Sbjct: 1097 EQ---RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 1153
Query: 478 PSDSVPA-----RITSFSRNIVT-PWKENISLSCNKV------GVPAPATTWT-MNGVGL 524
S +P +I SR+ +T W ++V A W +N V +
Sbjct: 1154 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 1213
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
T+ + S+ T + + N S + + + P +P V D+
Sbjct: 1214 --TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDT 1271
Query: 585 YADSLHLQWS-DQGDGGSPILGYVINYKR-EHGDWEELQ-VEAGTSEHVLPNLWCGTRYQ 641
S+ L WS + +GGS + GY+I ++ + +W + E+ L +L G Y+
Sbjct: 1272 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYR 1331
Query: 642 LYITAFNRIGTGLPCDI 658
+ A N G G P ++
Sbjct: 1332 FRVLACNAGGPGEPAEV 1348
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/171 (29%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSR-TIQISWTQPYA-GNSPIINYIVQYKEAPESW 114
TVD + P+ P VI+ + + ISW P G S I NY+V+ EA E
Sbjct: 1937 TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEG- 1995
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSG 171
+ Q V SVT+ + NL Y+ R+ A+N G S+P S V + + E P G
Sbjct: 1996 -AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP-G 2053
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
P + A + +V W+PP D I YY+ +E N + + +
Sbjct: 2054 APGKPTITAVTKDSCVVAWKPPASD-GGAKIRNYYLEKREKKQNKWISVTT 2103
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 8/186 (4%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEH 629
+P P I V + + + +QW+ + DGG+ I Y+++ + +E W + + +
Sbjct: 466 IPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVVYDT 525
Query: 630 VLP--NLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTV 684
L +L G YQ +TA N G P + + P P +++ ++
Sbjct: 526 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPSAPRVVDTTKHSI 585
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W DGG I+ +V+E +E QW V + F+V L Y R+
Sbjct: 586 SLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVA 645
Query: 744 AHNNAG 749
A N G
Sbjct: 646 AVNVKG 651
Score = 58.0 bits (134), Expect = 2e-07
Identities = 117/551 (21%), Positives = 204/551 (37%), Gaps = 57/551 (10%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+VQ A Y +++ N G + V++ + P+GP + +EA +++W
Sbjct: 1917 NVQRKTHAGKYKVQL--SNVFGTVDAILDVEIQDKPDKPTGP---IVIEALLKNSAVISW 1971
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT--LSG 248
+PP D G+ + YV V GA + + +A S TT +
Sbjct: 1972 KPPADD--GGSWITNYV----------VEKCEAKEGAEWQL-----VSSAISVTTCRIVN 2014
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEP 306
L ++A Y V A N+ ++ P PG A++ S V+W+P
Sbjct: 2015 LTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKP 2074
Query: 307 PPMRGRNGILQGY-RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G I Y W T++I ++ L Y V
Sbjct: 2075 PASDGGAKIRNYYLEKREKKQNKWIS---VTTEEIRETVFSVKNLIEGLEYEFRVKCENL 2131
Query: 366 AGDGVRAAPVYCHT-EEDVPSAPADIKAAVSSRN-----KILVSWLPPSSPNGVLVGYTL 419
G+ + T + DVP K + + N + P ++ Y
Sbjct: 2132 GGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQ 2191
Query: 420 YMSVIEDGRE------EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+I DG + +G + +++ S + + RAT+Q S G A+
Sbjct: 2192 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQ---GGSV---SGTASLE 2245
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
V V +P + + E +S+ G P P TW +++ V
Sbjct: 2246 VEVPAKIHLPKTLEGMGA-VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 2304
Query: 534 SDGTLTISM----TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADS 588
+ T + + D+G Y +N G D+ T ++V P PP + V D+ DS
Sbjct: 2305 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDS 2364
Query: 589 LHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITA 646
++L W++ DGGS I Y++ + W + +A + + + NL+ T YQ + A
Sbjct: 2365 VNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIA 2423
Query: 647 FNRIGTGLPCD 657
N+ G P +
Sbjct: 2424 ENKFGLSKPSE 2434
Score = 57.2 bits (132), Expect = 3e-07
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GT 537
++ ARI + R++ E+ SC+ G P P TW G L ++ R V++ T
Sbjct: 3785 TLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKST 3844
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
IS Q++D GNY+ VEN G+ E +T+ ++
Sbjct: 3845 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 3878
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P + ++ ++ + W +P G I+ Y V+Y+++ +S W + ++ I
Sbjct: 1658 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQF 1717
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T + L AT Y R+ AEN G S P + T ++ SG +R E K T
Sbjct: 1718 T---IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVT 1770
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/302 (24%), Positives = 109/302 (36%), Gaps = 37/302 (12%)
Query: 102 NYIVQYKEAPESWPSTPQKVIVPGSV--TSASVQNLQPATSYHLRIIAENRLGQSEPSQP 159
NYIV+ +E+ T +V SV T V +L Y R+ +ENR G S+P +
Sbjct: 2 NYIVEKRES-----GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLES 56
Query: 160 VQVTTTEE-VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
+ VP P V S+ + + WE P D I+GY+V +E N T+
Sbjct: 57 APIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD-GGSKIIGYWVEKKERN---TI 112
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
L V +E ++GL + Y A N+
Sbjct: 113 LWVK-----ENKVPCLE------CNYKVTGLVEGLEYQFRTYALNA-AGVSKASEASRPI 160
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD-----WYGNE 333
M P PG + +V + W P G + ++ GY + PV++ W
Sbjct: 161 MAQNPVDAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVV-GYIIERKPVSEVGDGRWLKCN 219
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG----DGVRAAPVYCHTEEDVPSAPAD 389
+ +S T++ L Y V A AAG PV C E P A D
Sbjct: 220 YTI---VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 276
Query: 390 IK 391
+
Sbjct: 277 AR 278
Score = 43.2 bits (97), Expect = 0.005
Identities = 145/720 (20%), Positives = 262/720 (36%), Gaps = 82/720 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE----SWPSTPQKVIVPG 125
+ P V D Q T+ + W+ P Y G S ++ YI++ K E W ++
Sbjct: 167 DAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 226
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLG----QSEPSQPVQVTTTEEVPSGPPQDVR---- 177
T V L +Y R++A+N G SE + PV E P D R
Sbjct: 227 FFT---VTALSEGDTYEFRVLAKNAAGVISKGSESTGPV-TCRDEYAPPKAELDARLHGD 282
Query: 178 -VEAKSSTELI----VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
V ++ ++L+ V +P + +W G +EL+ V + A+ ++
Sbjct: 283 LVTIRAGSDLVLDAAVGGKPEPKIIWT-------KGDKELDLCEKVSLQYTGKRATAVIK 335
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
+ + + + T+ A +V+V+ +S P P G L
Sbjct: 336 FCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS------------------PG-PCGKLTV 376
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
+ ++ + ++W P G I Y V + N V + L ++ L +
Sbjct: 377 SRVTQEKCTLAWSLPQEDGGAEITH-YIVERRETSRL--NWVIVEGECPTLSYVVTRLIK 433
Query: 353 YTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y V A G G V + P+ +PS P + + + I++ W P S
Sbjct: 434 NNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESD 493
Query: 411 NG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
G + Y + E R +K + T TS +QF V+A G E
Sbjct: 494 GGNEISNYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLM-EGCDYQFRVTAVNAAGNSE 552
Query: 470 ATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVG 523
+ + S P+ + +V K +ISL+ K G M
Sbjct: 553 PSERSNFI-SCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKD 611
Query: 524 LESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP---P 577
+ R + ++ + T+ + ++ + N+ G E + ++ P + P
Sbjct: 612 TDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP 671
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEHVLPNL 634
L + D ++ ++ + G VI + ++ D + T + L +
Sbjct: 672 DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 731
Query: 635 WCGTRY---QLYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKHSQMITLNTTTVTVWLD 689
RY + I A N+ G +V Y T G P VK K ++ ++ T+T W
Sbjct: 732 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE---VSRDSVTIT-WEI 787
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG I +++E RE + ++ V+ T ++ +SGL + R+ N G
Sbjct: 788 PTIDGGAPINNYIVEKREAAMRAFKTVTTKCSKT--LYRISGLVEGTMHYFRVLPENIYG 845
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-----KNVSSDG 536
+P +I + +I + ++++C G P P TW+ G + S + +N
Sbjct: 4554 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 4613
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TL I Q D G YT S+ N G D T + ++
Sbjct: 4614 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 4648
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
P S P +T V+ + G P P WT +G + + +S D
Sbjct: 4074 PISSKPVIVTGLQDTTVSS-DSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG 4132
Query: 538 ---LTISMTQSADSGNYTCSVENIHG 560
L I T ++DSG YTC+V+N G
Sbjct: 4133 GFFLEIHKTDTSDSGLYTCTVKNSAG 4158
Score = 35.5 bits (78), Expect = 1.1
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P + G + I NY ++ +E ++ W S + I T SV+NL Y R+
Sbjct: 2070 VAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI---RETVFSVKNLIEGLEYEFRV 2126
Query: 146 IAENRLGQSEPSQPVQ-VTTTEEVPSGPP 173
EN G+SE S+ + +T +VP P
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPIQAP 2155
Score = 35.1 bits (77), Expect = 1.4
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++E RE W+LV++SV+ T+ V+ LT Y R+++ N G
Sbjct: 3 YIVEKRESGTTAWQLVNSSVKRTQ--IKVTHLTKYMEYSFRVSSENRFG 49
Score = 33.9 bits (74), Expect = 3.2
Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVS-SDGTLTI 540
A I +FS + + + L N G A W +NGV L ++ R VS SD TLTI
Sbjct: 4266 AEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTI 4323
Query: 541 SMTQSADSGNYTC 553
D G TC
Sbjct: 4324 KQASHRDEGILTC 4336
Score = 32.7 bits (71), Expect = 7.5
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
D P RIT R+ P +N N P W NGV L ES+ ++ G L
Sbjct: 3598 DHAP-RITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVL 3656
Query: 539 TISM--TQSADSGNYTCSVENIHGRDEVTYTVEV 570
T+ + + DSG Y N G T++V
Sbjct: 3657 TLEILDCHTDDSGTYRAVCTNYKGERSDYATLDV 3690
Score = 32.7 bits (71), Expect = 7.5
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSV 555
+N+ + G P+P W N + + + ++S +L I +DSG YT
Sbjct: 4376 QNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 4435
Query: 556 ENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS 594
+N G+ T ++ V + P VV + LQ S
Sbjct: 4436 KNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGS 4474
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 143 bits (347), Expect = 3e-33
Identities = 158/698 (22%), Positives = 265/698 (37%), Gaps = 44/698 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P RV+D +I ++WT+P Y G + I+ Y+++ +E + W +
Sbjct: 569 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRN-- 626
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +L+ Y R+ A N G SE S+ + E P ++ + K + +
Sbjct: 627 TEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIR 686
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G L V ++ +I G R + + S +
Sbjct: 687 A-----------GASLRLMVS---VSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 732
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ ++ A ++A N + D P P +++ +S SV ++WE P
Sbjct: 733 KVNRYDAGKYTIEAENQ---SGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIP 788
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
+ G + Y V VT + S +SGL T + V G
Sbjct: 789 TIDG-GAPINNYIVEKREAA--MRAFKTVTTKCSKTLYRISGLVEGTMHYFRVLPENIYG 845
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIED 426
G +VP PA ++ +++ + ++W P G L GY L +
Sbjct: 846 IGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVL--EACKA 903
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR- 485
G E L P+ L H + + F + A G E VT + +
Sbjct: 904 GTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP 963
Query: 486 ----ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTL 538
T + I P + L G P PA +W G L + R V + L
Sbjct: 964 TIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKL 1023
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS-D 595
TI T D+G YT ++N+ G T V + P PP + + + A S+ + W
Sbjct: 1024 TIRETTIRDTGEYTLELKNVTGTTLETIKVIILDKPGPPTGPIKIDEIDATSITISWEPP 1083
Query: 596 QGDGGSPILGYVINYKREH-GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG- 653
+ DGG+P+ GYV+ + H W + S L G Y + A NR G G
Sbjct: 1084 ELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGS 1143
Query: 654 -LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP 711
L +++ + +P P+ Q+ ++ +T+ W DGG + +++E +E+
Sbjct: 1144 YLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRAD 1203
Query: 712 QWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V N V T + +GLT Y+ R+TA N G
Sbjct: 1204 RWVRV-NKVPVTMTRYRSTGLTEGLEYEHRVTAINARG 1240
Score = 112 bits (270), Expect = 6e-24
Identities = 148/604 (24%), Positives = 222/604 (36%), Gaps = 47/604 (7%)
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P ++++ +T + ++WEPP+ D + GY V ++ A PG
Sbjct: 1059 PGPPTGPIKIDEIDATSITISWEPPELD-GGAPLSGYVVEQRD---------AHRPGWLP 1108
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLP 286
+ RS + L + Y V A N + P P
Sbjct: 1109 VS------ESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG-P 1161
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHT 345
P LQ +S + ++W PP G + + GY V V D + + V ++ +
Sbjct: 1162 PETLQIFDVSRDGMTLTWYPPEDDGGSQVT-GYIVERKEVRADRWVRVNKVPVTMTRYRS 1220
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILV 402
T GL Y V A A G G + P D P P + + ++R + +
Sbjct: 1221 T--GLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 1278
Query: 403 SWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
+W P G V GY + M ++ + E T + + P A ++F V A
Sbjct: 1279 AWSVPEDEGGSKVTGYLIEMQKVD--QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 1336
Query: 462 STRLGEGEATRV---VTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATT 516
G GE V V V P + I I L+ G P P
Sbjct: 1337 CNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICK 1396
Query: 517 WTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
WT G + S T L I DSG Y +EN G+ V V V P
Sbjct: 1397 WTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPN 1456
Query: 576 PPI--LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR-EHGDWEELQVEAGTSEHVL 631
P L D S+ + W D GG+ ILGY++ + W + + V+
Sbjct: 1457 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVV 1516
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMITLNTTTVTVWLD 689
L Y ++A N+ G P T T P +P + L+ T +V L
Sbjct: 1517 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSL- 1575
Query: 690 SWG----DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
SW DGG + + IE +E S + + N Q T +++V+GL P A YQ RI A
Sbjct: 1576 SWSRPKDDGGSRVTGYYIERKETSTDKV-VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQ 1634
Query: 746 NNAG 749
N+ G
Sbjct: 1635 NDVG 1638
Score = 102 bits (245), Expect = 6e-21
Identities = 155/634 (24%), Positives = 248/634 (39%), Gaps = 64/634 (10%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
++ EN+ G+ V+V + P GP + ++ +S + V+W PP D +ILG
Sbjct: 1434 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRS---VRVSWRPPADD-GGADILG 1489
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN- 263
Y + +E+ P A YT+ + GT+ + GL+++ Y V A N
Sbjct: 1490 YILERREV-----------PKAAWYTIDS-RVRGTS---LVVKGLKENVEYHFRVSAENQ 1534
Query: 264 ---SRXXXXXXXXXXXXXME--DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
S+ + + PS PP L ++ SV +SW P G + +
Sbjct: 1535 FGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLD---VTKSSVSLSWSRPKDDGGSRVTGY 1591
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPV 375
Y TD + QI+ T++GL Y + A G + PV
Sbjct: 1592 YIERKETSTDKVVRHNKT--QITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 1649
Query: 376 YCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK 434
C D PS P +++ S++ + + W P G ++GY + D + ++K
Sbjct: 1650 VCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNK 1709
Query: 435 RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATR----VVTVLPSDSVPARITSF 489
+ T AT ++F V A G R + T L S P I
Sbjct: 1710 ERIKDKQF---TIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-IRKE 1765
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSA 546
+++ T E LSC VG P P W G L + + +SSDG TLT+ +
Sbjct: 1766 MKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE 1825
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ-PPILAVVDSY----ADSLHLQWSDQGDGGS 601
D G YTC N G E + + ++ PQ P + + Y +L L G
Sbjct: 1826 DEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIG-RPV 1884
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEH----VLPNLWCGTRYQLY-ITAFNRIGTGLPC 656
P + + K E + +E +EH V+ N+ T Y + N GT
Sbjct: 1885 PAMTWFHGQKLLQNS-ENITIE--NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAI 1941
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRL 715
V K P P + + N+ ++ W DGG I +V+E E + +W+L
Sbjct: 1942 LDVEIQDKPDKPTGPIVIEALLKNSAVIS-WKPPADDGGSWITNYVVEKCEAKEGAEWQL 2000
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
VS+++ T + LT A Y R++A N G
Sbjct: 2001 VSSAISVT--TCRIVNLTENAGYYFRVSAQNTFG 2032
Score = 97.5 bits (232), Expect = 2e-19
Identities = 119/495 (24%), Positives = 200/495 (40%), Gaps = 34/495 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQ 339
VP P + +S+ ++ + WE P G + I+ GY V W +
Sbjct: 66 VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKII-GYWVEKKERNTILWVKENKVPCLE 124
Query: 340 ISGLHTTL-SGLR-RYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ T L GL ++ Y++ + A + R P+ D P P R
Sbjct: 125 CNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR--PIMAQNPVDAPGRPGVTDV---QR 179
Query: 398 NKILVSWLPPSSPNGV-LVGYTLY---MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
+ + + W P+ G +VGY + +S + DGR + ++S + + +
Sbjct: 180 STVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFT--VTALSEGD 237
Query: 454 THQFWVSASTRLGE----GEATRVVTVLPSDSVP-ARITS-FSRNIVTPWK-ENISLSCN 506
T++F V A G E+T VT + P A + + ++VT ++ L
Sbjct: 238 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 297
Query: 507 KVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDE 563
G P P WT L+ + ++ G T I +DSG YT +V+N G
Sbjct: 298 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 357
Query: 564 VTYTVEVKVPPQP-PILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEE 619
V+ V+V P P L V + L WS Q DGG+ I Y++ +RE +W
Sbjct: 358 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVE-RRETSRLNWVI 416
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMI 677
++ E T +V+ L Y + A N+ G G+P + + A T+P P + +
Sbjct: 417 VEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV 476
Query: 678 TLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAA 736
+ + W DGG I ++++ RE +W V+ + V+ L
Sbjct: 477 GTGKEHIIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLMEGC 536
Query: 737 HYQLRITAHNNAGHA 751
YQ R+TA N AG++
Sbjct: 537 DYQFRVTAVNAAGNS 551
Score = 95.9 bits (228), Expect = 7e-19
Identities = 149/717 (20%), Positives = 266/717 (37%), Gaps = 69/717 (9%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVI 122
L +VP +P + V+D T+ ++W +P Y G S + Y+++ K E W V
Sbjct: 857 LVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKV---VT 913
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--------TEEVPSGPPQ 174
+ +V +V +L Y RI A+N G SEP + V T T ++ + P +
Sbjct: 914 LKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK 973
Query: 175 DVRVEAKSSTELI--VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
+ V A EL+ + PP W ++ G +L + V + + A T+R
Sbjct: 974 TIHVPAGRPVELVIPIAGRPPPAASW------FFAG-SKLRESERVTVETHTKVAKLTIR 1026
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
T L + + V + D P P G ++
Sbjct: 1027 ETTIRDTGEYTLELKNVTGTTLETIKV------------------IILDKPGPPTGPIKI 1068
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTKQISGLHTTLSGL 350
+ + + S+ +SWEPP + G L GY V A W ++VT+ + T L+
Sbjct: 1069 DEIDATSITISWEPPELDG-GAPLSGYVVEQRDAHRPGWLPVSESVTRS-TFKFTRLTEG 1126
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y + V G +++ + C + +P P ++ SR+ + ++W PP
Sbjct: 1127 NEYV-FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDD 1185
Query: 411 NGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA-THQFWVSASTRLGEG 468
G V GY + + R +K P T++ S ++ V+A G G
Sbjct: 1186 GGSQVTGYIVERKEVRADRWVRVNK---VPVTMTRYRSTGLTEGLEYEHRVTAINARGSG 1242
Query: 469 EATR-VVTVLPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGVG 523
+ +R ++ D + + + + ++SL+ ++ G M V
Sbjct: 1243 KPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVD 1302
Query: 524 LESTLRKNVSSDGTLTISMTQSADSGNY-----TCSVENIHGRDEVTYTVEVKVPPQPPI 578
+ N + ++T Y C+ EV TV+V + P
Sbjct: 1303 QHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPD 1362
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEH---VLP 632
+ + Y + + ++ PI G + + +E D + + A + H V+
Sbjct: 1363 YELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIK 1422
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWG 692
G + N+ G V P P I + + V+ W
Sbjct: 1423 EADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVS-WRPPAD 1481
Query: 693 DGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG IL +++E RE+ + W + + V+ T V V GL Y R++A N G
Sbjct: 1482 DGGADILGYILERREVPKAAWYTIDSRVRGTSLV--VKGLKENVEYHFRVSAENQFG 1536
Score = 81.8 bits (193), Expect = 1e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 36/308 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
PE P + D Q R++++SW P G + I+ YI++ +E P++ W + +V
Sbjct: 1458 PEGP--LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV----RG 1511
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTT---TEEVPSGPPQDVRVEAK 181
TS V+ L+ YH R+ AEN+ G S+P +PV T E PS PP+ + V K
Sbjct: 1512 TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV-TK 1570
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
SS L +W P+ D + GYY+ +E +++ V + T T
Sbjct: 1571 SSVSL--SWSRPKDD-GGSRVTGYYIERKETSTDKVV-------RHNKTQITT------- 1613
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQS 299
+ T++GL A Y + A N +D P PG L+ ++S S
Sbjct: 1614 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDS 1673
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
V + WE P G IL GY V Y D + + ++I T+ GL T Y
Sbjct: 1674 VTLQWEKPECDGGKEIL-GYWVEYRQSGD-SAWKKSNKERIKDKQFTIGGLLEATEYEFR 1731
Query: 360 VCAFTAAG 367
V A G
Sbjct: 1732 VFAENETG 1739
Score = 72.5 bits (170), Expect = 8e-12
Identities = 62/259 (23%), Positives = 104/259 (40%), Gaps = 18/259 (6%)
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGT------LTISMTQSADSGNYTCSVENIHGR 561
+G P PA TW L+++ +N++ + T + ++ + +G Y + N+ G
Sbjct: 1880 IGRPVPAMTWFHGQKLLQNS--ENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGT 1937
Query: 562 DEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQGD-GGSPILGYVINY--KREHGD 616
+ VE++ P P +V +S + W D GGS I YV+ +E +
Sbjct: 1938 VDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE 1997
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
W+ + + + NL Y ++A N G P ++ + KP
Sbjct: 1998 WQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGK 2057
Query: 677 ITLNTTT----VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
T+ T V W DGG I + +E RE Q +W V+ + E VFSV L
Sbjct: 2058 PTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTE-EIRETVFSVKNL 2116
Query: 733 TPAAHYQLRITAHNNAGHA 751
Y+ R+ N G +
Sbjct: 2117 IEGLEYEFRVKCENLGGES 2135
Score = 71.3 bits (167), Expect = 2e-11
Identities = 114/499 (22%), Positives = 192/499 (38%), Gaps = 44/499 (8%)
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE-DAVT 337
++D P P G + AL S +SW+PP G + I Y V + G E V+
Sbjct: 1946 IQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWI-TNYVVEKCEAKE--GAEWQLVS 2002
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVR-AAPVYCHTEEDVPSAPADIKAAV 394
IS + L Y V A G D + ++ V + + P AP
Sbjct: 2003 SAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITA 2062
Query: 395 SSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR-- 452
+++ +V+W PP+S G + Y+ + RE+ +K + + ET S
Sbjct: 2063 VTKDSCVVAWKPPASDGGAKI-RNYYL----EKREKKQNKWISVTTEEIRETVFSVKNLI 2117
Query: 453 --ATHQFWVSASTRLGEGEATRV-VTVLPSDSVPARITSFS---RNIVTPWKENISLSCN 506
++F V GE E + + + P VP + F RN+ ++ N +L C
Sbjct: 2118 EGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCK 2177
Query: 507 KVGVPAPATTWTMNGV-----GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
G P P W G GL+ +++ L I+ D+ Y N G
Sbjct: 2178 VTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGS 2237
Query: 562 DEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKR------ 612
T ++EV+VP + + ++ ++H + P G VI +++
Sbjct: 2238 VSGTASLEVEVPAKIHLPKTLEGMG-AVHALRGEVVSIKIPFSGKPDPVITWQKGQDLID 2296
Query: 613 EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYIT-AFNRIGTGLPCDIVHAYTKGTVPVKP 671
+G ++ + + TS V PN Y+ A NR G + VP P
Sbjct: 2297 NNGHYQVIVTRSFTS-LVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV---ADVPDPP 2352
Query: 672 KHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVS 730
+ ++ + +V + W + DGG I +++E + +W V QA E ++V
Sbjct: 2353 RGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG---QARETRYTVI 2409
Query: 731 GLTPAAHYQLRITAHNNAG 749
L YQ R+ A N G
Sbjct: 2410 NLFGKTSYQFRVIAENKFG 2428
Score = 66.5 bits (155), Expect = 5e-10
Identities = 38/101 (37%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+ ++V D ++ ++WT+P + G S I NYIV+ E W Q
Sbjct: 2348 VPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ-----AR 2402
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
T +V NL TSY R+IAEN+ G S+PS+P + T T+E
Sbjct: 2403 ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 2443
Score = 63.7 bits (148), Expect = 3e-09
Identities = 130/617 (21%), Positives = 230/617 (37%), Gaps = 55/617 (8%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ P +++V + ++ I+W P G +PI NYIV+ +EA T V
Sbjct: 762 YDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAFKT---VTTKC 818
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T + L T ++ R++ EN G EP + EVP P + V+ ST
Sbjct: 819 SKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST- 877
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ + WE P D G+ L YV + + G ++ V T T
Sbjct: 878 VTLAWEKPLYD--GGSRLTGYV------------LEACKAGTERWMKVVTLKPTVLEHTV 923
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
S L + Y ++A N + ++D+ LP + + + +++ V
Sbjct: 924 TS-LNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLP--TIDLSTMPQKTIHVPAG 980
Query: 306 PP-----PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
P P+ GR + + + + +++ L + +R Y++ +
Sbjct: 981 RPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 1040
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL 419
T G + V + P+ P IK I +SW PP G L GY +
Sbjct: 1041 KNVT--GTTLETIKVIILDKPGPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVV 1096
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE--ATRVVTVL 477
D G S + + + +R + F V+A+ R G G + V+
Sbjct: 1097 EQ---RDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 1153
Query: 478 PSDSVPA-----RITSFSRNIVT-PWKENISLSCNKV------GVPAPATTWT-MNGVGL 524
S +P +I SR+ +T W ++V A W +N V +
Sbjct: 1154 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 1213
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
T+ + S+ T + + N S + + + P +P V D+
Sbjct: 1214 --TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDT 1271
Query: 585 YADSLHLQWS-DQGDGGSPILGYVINYKR-EHGDWEELQ-VEAGTSEHVLPNLWCGTRYQ 641
S+ L WS + +GGS + GY+I ++ + +W + E+ L +L G Y+
Sbjct: 1272 TRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYR 1331
Query: 642 LYITAFNRIGTGLPCDI 658
+ A N G G P ++
Sbjct: 1332 FRVLACNAGGPGEPAEV 1348
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/171 (29%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSR-TIQISWTQPYA-GNSPIINYIVQYKEAPESW 114
TVD + P+ P VI+ + + ISW P G S I NY+V+ EA E
Sbjct: 1937 TVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEG- 1995
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSG 171
+ Q V SVT+ + NL Y+ R+ A+N G S+P S V + + E P G
Sbjct: 1996 -AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKP-G 2053
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
P + A + +V W+PP D I YY+ +E N + + +
Sbjct: 2054 APGKPTITAVTKDSCVVAWKPPASD-GGAKIRNYYLEKREKKQNKWISVTT 2103
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 8/186 (4%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEH 629
+P P I V + + + +QW+ + DGG+ I Y+++ + +E W + + +
Sbjct: 466 IPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVVYDT 525
Query: 630 VLP--NLWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTV 684
L +L G YQ +TA N G P + + P P +++ ++
Sbjct: 526 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPSAPRVVDTTKHSI 585
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W DGG I+ +V+E +E QW V + F+V L Y R+
Sbjct: 586 SLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVA 645
Query: 744 AHNNAG 749
A N G
Sbjct: 646 AVNVKG 651
Score = 58.0 bits (134), Expect = 2e-07
Identities = 117/551 (21%), Positives = 204/551 (37%), Gaps = 57/551 (10%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+VQ A Y +++ N G + V++ + P+GP + +EA +++W
Sbjct: 1917 NVQRKTHAGKYKVQL--SNVFGTVDAILDVEIQDKPDKPTGP---IVIEALLKNSAVISW 1971
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT--LSG 248
+PP D G+ + YV V GA + + +A S TT +
Sbjct: 1972 KPPADD--GGSWITNYV----------VEKCEAKEGAEWQL-----VSSAISVTTCRIVN 2014
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEP 306
L ++A Y V A N+ ++ P PG A++ S V+W+P
Sbjct: 2015 LTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKP 2074
Query: 307 PPMRGRNGILQGY-RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G I Y W T++I ++ L Y V
Sbjct: 2075 PASDGGAKIRNYYLEKREKKQNKWIS---VTTEEIRETVFSVKNLIEGLEYEFRVKCENL 2131
Query: 366 AGDGVRAAPVYCHT-EEDVPSAPADIKAAVSSRN-----KILVSWLPPSSPNGVLVGYTL 419
G+ + T + DVP K + + N + P ++ Y
Sbjct: 2132 GGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQ 2191
Query: 420 YMSVIEDGRE------EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
+I DG + +G + +++ S + + RAT+Q S G A+
Sbjct: 2192 GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQ---GGSV---SGTASLE 2245
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
V V +P + + E +S+ G P P TW +++ V
Sbjct: 2246 VEVPAKIHLPKTLEGMGA-VHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVI 2304
Query: 534 SDGTLTISM----TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADS 588
+ T + + D+G Y +N G D+ T ++V P PP + V D+ DS
Sbjct: 2305 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDASRDS 2364
Query: 589 LHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITA 646
++L W++ DGGS I Y++ + W + +A + + + NL+ T YQ + A
Sbjct: 2365 VNLTWTEPASDGGSKITNYIVEKCATTAERWLRVG-QARETRYTVINLFGKTSYQFRVIA 2423
Query: 647 FNRIGTGLPCD 657
N+ G P +
Sbjct: 2424 ENKFGLSKPSE 2434
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P + ++ ++ + W +P G I+ Y V+Y+++ +S W + ++ I
Sbjct: 1658 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQF 1717
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T + L AT Y R+ AEN G S P + T ++ SG +R E K T
Sbjct: 1718 T---IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVT 1770
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/302 (24%), Positives = 109/302 (36%), Gaps = 37/302 (12%)
Query: 102 NYIVQYKEAPESWPSTPQKVIVPGSV--TSASVQNLQPATSYHLRIIAENRLGQSEPSQP 159
NYIV+ +E+ T +V SV T V +L Y R+ +ENR G S+P +
Sbjct: 2 NYIVEKRES-----GTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLES 56
Query: 160 VQVTTTEE-VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
+ VP P V S+ + + WE P D I+GY+V +E N T+
Sbjct: 57 APIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD-GGSKIIGYWVEKKERN---TI 112
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
L V +E ++GL + Y A N+
Sbjct: 113 LWVK-----ENKVPCLE------CNYKVTGLVEGLEYQFRTYALNA-AGVSKASEASRPI 160
Query: 279 MEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD-----WYGNE 333
M P PG + +V + W P G + ++ GY + PV++ W
Sbjct: 161 MAQNPVDAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVV-GYIIERKPVSEVGDGRWLKCN 219
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG----DGVRAAPVYCHTEEDVPSAPAD 389
+ +S T++ L Y V A AAG PV C E P A D
Sbjct: 220 YTI---VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 276
Query: 390 IK 391
+
Sbjct: 277 AR 278
Score = 43.2 bits (97), Expect = 0.005
Identities = 145/720 (20%), Positives = 262/720 (36%), Gaps = 82/720 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE----SWPSTPQKVIVPG 125
+ P V D Q T+ + W+ P Y G S ++ YI++ K E W ++
Sbjct: 167 DAPGRPGVTDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 226
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLG----QSEPSQPVQVTTTEEVPSGPPQDVR---- 177
T V L +Y R++A+N G SE + PV E P D R
Sbjct: 227 FFT---VTALSEGDTYEFRVLAKNAAGVISKGSESTGPV-TCRDEYAPPKAELDARLHGD 282
Query: 178 -VEAKSSTELI----VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
V ++ ++L+ V +P + +W G +EL+ V + A+ ++
Sbjct: 283 LVTIRAGSDLVLDAAVGGKPEPKIIWT-------KGDKELDLCEKVSLQYTGKRATAVIK 335
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
+ + + + T+ A +V+V+ +S P P G L
Sbjct: 336 FCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS------------------PG-PCGKLTV 376
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
+ ++ + ++W P G I Y V + N V + L ++ L +
Sbjct: 377 SRVTQEKCTLAWSLPQEDGGAEITH-YIVERRETSRL--NWVIVEGECPTLSYVVTRLIK 433
Query: 353 YTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y V A G G V + P+ +PS P + + + I++ W P S
Sbjct: 434 NNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESD 493
Query: 411 NG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
G + Y + E R +K + T TS +QF V+A G E
Sbjct: 494 GGNEISNYLVDKREKESLRWTRVNKDYVVYDTRLKVTSLM-EGCDYQFRVTAVNAAGNSE 552
Query: 470 ATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVG 523
+ + S P+ + +V K +ISL+ K G M
Sbjct: 553 PSERSNFI-SCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKD 611
Query: 524 LESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP---P 577
+ R + ++ + T+ + ++ + N+ G E + ++ P + P
Sbjct: 612 TDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP 671
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGY---VINYKREHGDWEELQVEAGTSEHVLPNL 634
L + D ++ ++ + G VI + ++ D + T + L +
Sbjct: 672 DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 731
Query: 635 WCGTRY---QLYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKHSQMITLNTTTVTVWLD 689
RY + I A N+ G +V Y T G P VK K ++ ++ T+T W
Sbjct: 732 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKE---VSRDSVTIT-WEI 787
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
DGG I +++E RE + ++ V+ T ++ +SGL + R+ N G
Sbjct: 788 PTIDGGAPINNYIVEKREAAMRAFKTVTTKCSKT--LYRISGLVEGTMHYFRVLPENIYG 845
Score = 35.5 bits (78), Expect = 1.1
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P + G + I NY ++ +E ++ W S + I T SV+NL Y R+
Sbjct: 2070 VAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI---RETVFSVKNLIEGLEYEFRV 2126
Query: 146 IAENRLGQSEPSQPVQ-VTTTEEVPSGPP 173
EN G+SE S+ + +T +VP P
Sbjct: 2127 KCENLGGESEWSEISEPITPKSDVPIQAP 2155
Score = 35.1 bits (77), Expect = 1.4
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++E RE W+LV++SV+ T+ V+ LT Y R+++ N G
Sbjct: 3 YIVEKRESGTTAWQLVNSSVKRTQ--IKVTHLTKYMEYSFRVSSENRFG 49
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 143 bits (347), Expect = 3e-33
Identities = 121/448 (27%), Positives = 194/448 (43%), Gaps = 34/448 (7%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPST 117
R+ +L P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W
Sbjct: 606 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 665
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDV 176
+ PGSV SA V L P +Y R+IA N +G S PS P + T+ P P DV
Sbjct: 666 SK---YPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 721
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ E + +TW P G L Y V ++ + ++ TV G
Sbjct: 722 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG 770
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
SR + + Y + VQA N ED P P ++ ++
Sbjct: 771 -----SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMN 825
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGL 350
S ++ + W G L+ YR Y + + + + ++ G L +S L
Sbjct: 826 STAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRL 885
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
Y+NY + + GDG R+ T E VPSAP + + I + W P P
Sbjct: 886 FPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHP 945
Query: 411 NGVLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
NG+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GE
Sbjct: 946 NGIMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGE 1004
Query: 470 A-TRVVTVLPSDSVP-ARITSFSRNIVT 495
A T P+++ P A T+ +I T
Sbjct: 1005 AVTEESPAPPNEATPTAAYTNNQADIAT 1032
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 373 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 427
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 428 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 487
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 488 CVATNILGKAENQVRLEVKDP 508
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 250 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 309
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 310 GSIRHTISVRVKAAP 324
Score = 40.3 bits (90), Expect = 0.037
Identities = 65/294 (22%), Positives = 101/294 (34%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 508 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 566
Query: 541 SMTQSADSGNYTCSVENIHGRD-----------EVTYTVEVKV-----PPQPPILAVVDS 584
D G+YTC +D + T T + P +P L + D
Sbjct: 567 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 626
Query: 585 YADSLHLQWSDQGDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQ 641
S+ L W SPI YV+ ++ + G W + G+ + L YQ
Sbjct: 627 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQ 686
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGC 696
+ A N +G+ P Y P + + T W +++ G
Sbjct: 687 FRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGP 746
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
+ Y V R ++ W N+V + V G TP Y++R+ A N+ G
Sbjct: 747 NLRYIVKWRRRETREAW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 795
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 331 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 389
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 390 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 418
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 477 LPSD-SVPARITSFSR--NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+P D + P IT S +IV P ++NI + C G PAP+ WT N VS
Sbjct: 3 IPMDLTQPPTITKQSAKDHIVDP-RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 61
Query: 534 ---SDGTLTISMTQSAD----SGNYTCSVENIHG 560
GTL I G Y C N G
Sbjct: 62 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 95
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 142 bits (344), Expect = 6e-33
Identities = 116/428 (27%), Positives = 187/428 (43%), Gaps = 39/428 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N+R + +I +SW+ P II Y + ++E + P T
Sbjct: 524 VPGQPMNLRAEARSETSITLSWSPPR--QESIIKYELLFREGDHG--REVGRTFDP--TT 577
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V++L+P T Y R+ A + G + V+ T + PS PPQDV+ + ST ++V
Sbjct: 578 SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILV 637
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP + NG ++GY V ++ L S + V G ++ L
Sbjct: 638 SWRPPPPETHNGALVGYSVRYRPLGSEDP------------EPKEVNGIPPTTTQILLEA 685
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + A+ EDVPS PP ++ AL++ ++RV W P
Sbjct: 686 LEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWLGPV 745
Query: 309 MRGRNGILQGYRVTYAPVTDWYGN-----EDAV-------TKQISGLHTTLSGLRRYTNY 356
++G ++GY+V Y + G +D + T + ++ L+ T Y
Sbjct: 746 PGRQHGQIRGYQVHYVRMEGAEGRGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAY 805
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS-SPNGVLV 415
S+TV A+T GDG R+ P T+ V P + + +L W PP+ + ++
Sbjct: 806 SITVAAYTMKGDGARSKPKVVVTKGAVLGRPT-LSVQQTPEGSLLARWEPPAGTAEDQVL 864
Query: 416 GYTLYMSVIEDGREEGTHKRMLS--PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
GY L + GRE+ T L PS + S AT+ F ++A +R G GE
Sbjct: 865 GYRL-----QFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAE 919
Query: 474 VTVLPSDS 481
V +P D+
Sbjct: 920 VLSIPEDT 927
Score = 113 bits (273), Expect = 2e-24
Identities = 109/420 (25%), Positives = 175/420 (41%), Gaps = 33/420 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 331 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 384
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ P++V+ S+T +I
Sbjct: 385 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 444
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 445 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 489
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 490 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 548
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R + Y + + +G E T + + + L+ T Y+ + A + G
Sbjct: 549 ----RQESIIKYELLFREGD--HGREVGRTFDPTTSY-VVEDLKPNTEYAFRLAARSPQG 601
Query: 368 DGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWL--PPSSPNGVLVGYTLYMSVI 424
G V T + PSA P D+K ILVSW PP + NG LVGY++ +
Sbjct: 602 LGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL 661
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
E + P+T ++ A T +G G + V V + VP+
Sbjct: 662 GSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPS 721
Score = 112 bits (270), Expect = 6e-24
Identities = 95/360 (26%), Positives = 149/360 (41%), Gaps = 27/360 (7%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P++++ + +S I +SW P N ++ Y V+Y+ P + +P + T
Sbjct: 622 PQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQI 681
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L+ T Y + +A +G S PV V T E+VPS PP+ V EA ++T + V W
Sbjct: 682 LLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLW 741
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV---RTVEGAGTARSRTTLS 247
P +G I GY V + + GP + E TA ++
Sbjct: 742 LGPVPGRQHGQIRGYQVHYVRMEGAE----GRGPPRIKDVMLADAQWETDDTAEYEMVIT 797
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
LQ AY++ V AY + V P L S+ WEPP
Sbjct: 798 NLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP--TLSVQQTPEGSLLARWEPP 855
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDA---VTKQI--SGLHTTLSGLRRYTNYSVTVCA 362
+ +L GYR+ +G ED+ T + S T SG+ + Y + A
Sbjct: 856 AGTAEDQVL-GYRLQ-------FGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAA 907
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSAPADIKAA-VSSRNKILVSWLP--PSSPNGVLVGYTL 419
+ G G AA V E+ P ++AA +S +L+ WLP P+ NG +V YT+
Sbjct: 908 RSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTV 967
Score = 101 bits (243), Expect = 1e-20
Identities = 99/345 (28%), Positives = 149/345 (43%), Gaps = 43/345 (12%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V + + P P V ++T + +TW D N + + Y
Sbjct: 312 VAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW-----DSGNPDPVSY 362
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
YV E S S GP Y ++ E T +R ++ GL ++ Y + V A NS
Sbjct: 363 YV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNSEYEIWVSAVNSI 408
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA- 324
E P+ P +Q LS+ ++ V WE P NG+++GYRV Y
Sbjct: 409 GQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP--NGLIRGYRVYYTM 466
Query: 325 ----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
PV +W N D L TT+ L Y+V V AFT+ GDG + P+ T
Sbjct: 467 EPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 520
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
++ VP P +++A S I +SW PP + ++ Y L + GRE G R P
Sbjct: 521 QQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGREVG---RTFDP 575
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
+T S+ P + F ++A + G G T VV S P+
Sbjct: 576 TT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPS 619
Score = 80.2 bits (189), Expect = 4e-14
Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 10/254 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N++++C VG P P W G E ++ G + +T DS NYTC +
Sbjct: 261 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSL 317
Query: 560 GRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 318 GVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGN-PDPVSYYVIEYKSKSQDGP 375
Query: 619 -ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQM 676
+++ + T+ + + L + Y+++++A N IG G P + V T P P++ Q
Sbjct: 376 YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQA 435
Query: 677 ITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 436 RMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLED 494
Query: 736 AHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 495 ETYTVRVLAFTSVG 508
Score = 69.3 bits (162), Expect = 7e-11
Identities = 74/285 (25%), Positives = 107/285 (37%), Gaps = 24/285 (8%)
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
+ NLQP T+Y + + A G S+P V T V P V+ + S L+ WE
Sbjct: 796 ITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGS--LLARWE 853
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
PP +LGY + F +S + P + R T SG+ K
Sbjct: 854 PPAGTA-EDQVLGYRLQFGREDSTPLATLEFPP---------------SEDRYTASGVHK 897
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA-LSSQSVRVSWEPPPMR 310
A Y + A SR ED P P L+ S+ +V + W PP
Sbjct: 898 GATYVFRLAA-RSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA 956
Query: 311 GRNGILQGYRVTYAPVTDWYGNED----AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
RNG + Y V + A + + TL GL+ T Y + V A T
Sbjct: 957 ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENAVTLQGLKPDTAYDLQVRAHTRR 1016
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
G G + PV T +P + K + + +L+SW P + N
Sbjct: 1017 GPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYN 1061
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 85 TIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKVIV---PGSVTSASVQNLQPAT 139
T+ + W P N I+ Y V +EA P+ ++ PG+ + ++Q L+P T
Sbjct: 945 TVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENAVTLQGLKPDT 1004
Query: 140 SYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
+Y L++ A R G S PV+ T P++ +V+ T ++++WE P
Sbjct: 1005 AYDLQVRAHTRRGPGPFSPPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFP 1057
Score = 45.6 bits (103), Expect = 0.001
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 15/195 (7%)
Query: 116 STPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
STP + P S + + +Y R+ A +R G E + V ++ E+ P G PQ
Sbjct: 875 STPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEV-LSIPEDTPRGHPQ 933
Query: 175 DVRVEAKSST-ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ +S +++ W PP NG I+ Y V +E A G A T
Sbjct: 934 ILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVRE---------AGALGPARETELP 984
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRX-XXXXXXXXXXXXMEDVPSLPPGALQC 292
A + TL GL+ AY + V+A+ R + D + P +
Sbjct: 985 AAAEPGAENAVTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRD--QVSPKNFKV 1042
Query: 293 NALSSQSVRVSWEPP 307
+ SV +SWE P
Sbjct: 1043 KMIMKTSVLLSWEFP 1057
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVW 687
E V+ NL T Y + + A+ G G TKG V +P S T + + W
Sbjct: 793 EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARW 852
Query: 688 LDSWGDGGCGILYFVIEY-REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
G +L + +++ RE S P L + +E ++ SG+ A Y R+ A +
Sbjct: 853 EPPAGTAEDQVLGYRLQFGREDSTP---LATLEFPPSEDRYTASGVHKGATYVFRLAARS 909
Query: 747 NAG 749
G
Sbjct: 910 RGG 912
>AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]
protein.
Length = 1399
Score = 142 bits (343), Expect = 8e-33
Identities = 115/428 (26%), Positives = 186/428 (43%), Gaps = 39/428 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N+R + +I +SW+ P II Y + ++E + P T
Sbjct: 1 VPGQPMNLRAEARSETSITLSWSPPR--QESIIKYELLFREGDHG--REVGRTFDP--TT 54
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V++L+P T Y R+ A + G + V+ T + PS PPQDV+ + ST ++V
Sbjct: 55 SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILV 114
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP + NG ++GY V ++ L S + V G ++ L
Sbjct: 115 SWRPPPPETHNGALVGYSVRYRPLGSEDP------------EPKEVNGIPPTTTQILLEA 162
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y + A+ EDVPS PP ++ AL++ ++RV W P
Sbjct: 163 LEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPA 222
Query: 309 MRGRNGILQGYRVTYAPVTDWYGN-----EDAV-------TKQISGLHTTLSGLRRYTNY 356
++G ++GY+V Y + +D + T + ++ L+ T Y
Sbjct: 223 PGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAY 282
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS-SPNGVLV 415
S+TV A+T GDG R+ P T+ V P + + +L W PP+ + ++
Sbjct: 283 SITVAAYTMKGDGARSKPKVVVTKGAVLGRPT-LSVQQTPEGSLLARWEPPAGTAEDQVL 341
Query: 416 GYTLYMSVIEDGREEGTHKRMLS--PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
GY L + GRE+ T L PS + S AT+ F ++A +R G GE
Sbjct: 342 GYRL-----QFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAE 396
Query: 474 VTVLPSDS 481
V +P D+
Sbjct: 397 VLSIPEDT 404
Score = 116 bits (279), Expect = 5e-25
Identities = 96/360 (26%), Positives = 150/360 (41%), Gaps = 27/360 (7%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P++++ + +S I +SW P N ++ Y V+Y+ P + +P + T
Sbjct: 99 PQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQI 158
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L+ T Y + +A +G S PV V T E+VPS PP+ V EA ++T + V W
Sbjct: 159 LLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLW 218
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV---RTVEGAGTARSRTTLS 247
P +G I GY V + + A GP + E TA ++
Sbjct: 219 RSPAPGRQHGQIRGYQVHYVRMEGAE----ARGPPRIKDVMLADAQWETDDTAEYEMVIT 274
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
LQ AY++ V AY + V P L S+ WEPP
Sbjct: 275 NLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP--TLSVQQTPEGSLLARWEPP 332
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDA---VTKQI--SGLHTTLSGLRRYTNYSVTVCA 362
+ +L GYR+ +G ED+ T + S T SG+ + Y + A
Sbjct: 333 AGTAEDQVL-GYRLQ-------FGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAA 384
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSAPADIKAA-VSSRNKILVSWLP--PSSPNGVLVGYTL 419
+ G G AA V E+ P ++AA +S +L+ WLP P+ NG +V YT+
Sbjct: 385 RSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTV 444
Score = 112 bits (270), Expect = 6e-24
Identities = 92/336 (27%), Positives = 152/336 (45%), Gaps = 43/336 (12%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
G P ++R EA+S T + ++W PP+++ +I+ Y + F+E + V P SY
Sbjct: 3 GQPMNLRAEARSETSITLSWSPPRQE----SIIKYELLFREGDHGREVGRTFDPT-TSYV 57
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL 290
V L+ + YA + A + + ++ PS PP +
Sbjct: 58 VED---------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDV 102
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---- 346
+C ++ S ++ VSW PPP NG L GY V Y P+ G+ED K+++G+ T
Sbjct: 103 KCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPL----GSEDPEPKEVNGIPPTTTQI 158
Query: 347 -LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSW 404
L L ++T Y +T A T G G ++PV T+EDVPSA P ++A + I V W
Sbjct: 159 LLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLW 218
Query: 405 LPPS--SPNGVLVGYTLYMSVIEDGREEGTHK---RMLSPS------TLSHE--TSRSPP 451
P+ +G + GY ++ +E G + ML+ + T +E + P
Sbjct: 219 RSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQP 278
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARIT 487
+ V+A T G+G ++ V+ +V R T
Sbjct: 279 ETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPT 314
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/285 (25%), Positives = 107/285 (37%), Gaps = 24/285 (8%)
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
+ NLQP T+Y + + A G S+P V T V P V+ + S L+ WE
Sbjct: 273 ITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGS--LLARWE 330
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
PP +LGY + F +S + P + R T SG+ K
Sbjct: 331 PPAGTA-EDQVLGYRLQFGREDSTPLATLEFPP---------------SEDRYTASGVHK 374
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNA-LSSQSVRVSWEPPPMR 310
A Y + A SR ED P P L+ S+ +V + W PP
Sbjct: 375 GATYVFRLAA-RSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPA 433
Query: 311 GRNGILQGYRVTYAPVTDWYGNED----AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
RNG + Y V + A + + TL GL+ T Y + V A T
Sbjct: 434 ERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRR 493
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
G G + PV T +P + K + + +L+SW P + N
Sbjct: 494 GPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPDNYN 538
Score = 48.4 bits (110), Expect = 1e-04
Identities = 90/401 (22%), Positives = 147/401 (36%), Gaps = 46/401 (11%)
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
VP P +++A S I +SW PP + ++ Y L + GRE G R P+T
Sbjct: 1 VPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGREVG---RTFDPTT- 54
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVV---TVLPSDSVPAR----ITSFSRNIVT 495
S+ P + F ++A + G G T VV T+ S P + ++ S I+
Sbjct: 55 SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILV 114
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTISMTQSADSGNYTCS 554
W+ + N V + +G E K V+ T T + ++ +
Sbjct: 115 SWRPPPPETHNGALV---GYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRI 171
Query: 555 VENIHGR-------DEVTYTVEVKVPPQPPILAVVDSY-ADSLHLQWSDQGDG--GSPIL 604
H V + VP PP ++ A ++ + W G I
Sbjct: 172 TTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIR 231
Query: 605 GYVINYKREHG---------------DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNR 649
GY ++Y R G D + + E V+ NL T Y + + A+
Sbjct: 232 GYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTM 291
Query: 650 IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEY-REM 708
G G TKG V +P S T + + W G +L + +++ RE
Sbjct: 292 KGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGRED 351
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S P L + +E ++ SG+ A Y R+ A + G
Sbjct: 352 STP---LATLEFPPSEDRYTASGVHKGATYVFRLAARSRGG 389
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 85 TIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKVIV---PGSVTSASVQNLQPAT 139
T+ + W P N I+ Y V +EA P+ ++ PG+ + ++Q L+P T
Sbjct: 422 TVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDT 481
Query: 140 SYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
+Y L++ A R G S PV+ T P++ +V+ T ++++WE P
Sbjct: 482 AYDLQVRAHTRRGPGPFSPPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEFP 534
Score = 45.2 bits (102), Expect = 0.001
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 15/195 (7%)
Query: 116 STPQKVI-VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
STP + P S + + +Y R+ A +R G E + V ++ E+ P G PQ
Sbjct: 352 STPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEV-LSIPEDTPRGHPQ 410
Query: 175 DVRVEAKSST-ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRT 233
+ +S +++ W PP NG I+ Y V +E A G A T
Sbjct: 411 ILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVRE---------AGALGPARETELP 461
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRX-XXXXXXXXXXXXMEDVPSLPPGALQC 292
A + TL GL+ AY + V+A+ R + D + P +
Sbjct: 462 AAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRD--QVSPKNFKV 519
Query: 293 NALSSQSVRVSWEPP 307
+ SV +SWE P
Sbjct: 520 KMIMKTSVLLSWEFP 534
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 141 bits (342), Expect = 1e-32
Identities = 101/361 (27%), Positives = 163/361 (45%), Gaps = 32/361 (8%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
S +P P+++ + SR +++SW P I + V + ++ PG
Sbjct: 425 SSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN-RERALNTTQPG 483
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSST 184
S+ +V NL+P Y R++A N G E SQP++V T E+ GP ++++ + S T
Sbjct: 484 SL-QLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 542
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+++TWEPP NG + GY + E+++ I G SY
Sbjct: 543 SILITWEPPAYA--NGPVQGYRLFCTEVSTGKEQNIEVD--GLSYK-------------- 584
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+K Y++ AYN + DVPS PP + ++S+S++VSW
Sbjct: 585 -LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSW 643
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
PPP +NG + GY++ + T + T + + L +GL + + YS V A T
Sbjct: 644 LPPPSGTQNGFITGYKIRHRKTT---RRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMT 700
Query: 365 AAGDG------VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
G G P E VP P+ + + N I++SW PP +PN V+ GY
Sbjct: 701 VNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSWTPPLNPNIVVRGYI 759
Query: 419 L 419
+
Sbjct: 760 I 760
Score = 95.1 bits (226), Expect = 1e-18
Identities = 97/334 (29%), Positives = 139/334 (41%), Gaps = 40/334 (11%)
Query: 146 IAENRLGQSEPSQ----PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
+AEN G ++ S P + V P+DV SS + ++W PP GN
Sbjct: 401 VAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEA--KGN 458
Query: 202 ILGYYVGF-QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
I + V F +E ++ L + PG TV L+ A Y V
Sbjct: 459 IQTFTVFFSREGDNRERALNTTQPGSLQLTV---------------GNLKPEAMYTFRVV 503
Query: 261 AYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
AYN + VP P LQ + S S+ ++WEPP NG +QG
Sbjct: 504 AYNEWGPGESSQPIKVATQPELQVPG-PVENLQAVSTSPTSILITWEPPAYA--NGPVQG 560
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
YR+ V+ G E + ++ GL L GL+++T YS+ A+ G GV +
Sbjct: 561 YRLFCTEVST--GKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVV 616
Query: 379 TEEDVPSA-PADIKAAVSSRNKILVSWLPPSS--PNGVLVGYTL-YMSVIEDGREEGTHK 434
T DVPSA P ++ V + I VSWLPP S NG + GY + + G E
Sbjct: 617 TLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME---- 672
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
L P+ L + + + + F VSA T G G
Sbjct: 673 -TLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTG 705
Score = 82.2 bits (194), Expect = 9e-15
Identities = 92/394 (23%), Positives = 164/394 (41%), Gaps = 34/394 (8%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV-TKQI 340
+PS P + +SS+ VR+SW PP G +Q + V ++ D E A+ T Q
Sbjct: 428 LPSAPRDVVPV-LVSSRFVRLSWRPPAEA--KGNIQTFTVFFSREGD--NRERALNTTQP 482
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRN 398
L T+ L+ Y+ V A+ G G + P+ T+ + VP +++A +S
Sbjct: 483 GSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 542
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
IL++W PP+ NG + GY L+ + + G+E+ + LS++ +
Sbjct: 543 SILITWEPPAYANGPVQGYRLFCTEVSTGKEQN-----IEVDGLSYKLEGLKKFTEYSLR 597
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
A R G G +T +TV+ VP ++ +N+ + S+ + + P+
Sbjct: 598 FLAYNRYGPGVSTDDITVVTLSDVP---SAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGF 654
Query: 519 MNGVGL---ESTLRKNVSS--DGTLTISMTQSADSGNYTCSVE----NIHGRDEVTYTVE 569
+ G + ++T R + + L T Y+ V N G YT E
Sbjct: 655 ITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAE 714
Query: 570 V--------KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQ 621
+VP QP L V + + + W+ + + GY+I Y E ++
Sbjct: 715 TPENDLDESQVPDQPSSLH-VRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVR 773
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
V++ + + L + Y + + AFN G G+P
Sbjct: 774 VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVP 807
Score = 79.4 bits (187), Expect = 7e-14
Identities = 91/396 (22%), Positives = 155/396 (39%), Gaps = 29/396 (7%)
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
+PSAP D+ + S + +SW PP+ G + +T++ S D RE + P +L
Sbjct: 428 LPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQ--PGSL 485
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL--PSDSVPARITSFSRNIVTPWKEN 500
P A + F V A G GE+++ + V P VP + + +P
Sbjct: 486 QLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSIL 545
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCS--VENI 558
I+ P + + + + +N+ DG L+ + Y+ N
Sbjct: 546 ITWE-PPAYANGPVQGYRLFCTEVSTGKEQNIEVDG-LSYKLEGLKKFTEYSLRFLAYNR 603
Query: 559 HG----RDEVTYTVEVKVPPQPP---ILAVVDSYADSLHLQW--SDQGDGGSPILGYVIN 609
+G D++T VP PP L VV+S S+ + W G I GY I
Sbjct: 604 YGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSR--SIKVSWLPPPSGTQNGFITGYKIR 661
Query: 610 YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT------ 663
+++ E +E ++ L G++Y ++A GTG P + A T
Sbjct: 662 HRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLD 721
Query: 664 KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQAT 723
+ VP +P + + W + ++I Y + P V V +
Sbjct: 722 ESQVPDQPSSLHVRPQTNCIIMSWTPPLNPN-IVVRGYIIGYG-VGSPYAETVR--VDSK 777
Query: 724 ERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
+R +S+ L ++HY + + A NNAG + LY T
Sbjct: 778 QRYYSIERLESSSHYVISLKAFNNAGEGVPLYESAT 813
Score = 67.3 bits (157), Expect = 3e-10
Identities = 88/433 (20%), Positives = 164/433 (37%), Gaps = 32/433 (7%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + SR+I++SW P +G N I Y +++++
Sbjct: 610 TDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRG 669
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSG 171
+ + P ++ L+ + Y ++ A G PS T E +
Sbjct: 670 E---METLEPNNLWYLFT-GLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQV 725
Query: 172 PPQDVRVEAKSSTE-LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
P Q + + T +I++W PP N + GY +G+ + S + Y+
Sbjct: 726 PDQPSSLHVRPQTNCIIMSWTPPLNP--NIVVRGYIIGYG-VGSPYAETVRVDSKQRYYS 782
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--------- 281
+ +E + + +L + ++ +R + D
Sbjct: 783 IERLESS--SHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDL 840
Query: 282 -VPSLPPGALQCNALSSQSVRVSW--EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK 338
P LPP +Q AL+ +VRVSW P + ++ Y V + T + + ++
Sbjct: 841 STPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWR--TSFSASAKYKSE 898
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAV--S 395
+ L T +GL+ T Y +V + + T E P SAP D
Sbjct: 899 DTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDFTVITREG 958
Query: 396 SRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
++VSW PP NG + Y L+ ++ ++ + +S L+H+ +
Sbjct: 959 KPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMY 1018
Query: 456 QFWVSASTRLGEG 468
F + A G G
Sbjct: 1019 YFRIQARNSKGVG 1031
Score = 48.8 bits (111), Expect = 1e-04
Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 19/291 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTI 540
VP + N+ +I C G P P W NG V + S + V +
Sbjct: 329 VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL 388
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP--PQPPILA-----VVDSYADS--LHL 591
+ +S D G Y C EN G + + + V P P +L VV S + L
Sbjct: 389 GVVKS-DEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRL 447
Query: 592 QWSDQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITAFNR 649
W + I + + + RE + E + G+ + + NL Y + A+N
Sbjct: 448 SWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNE 507
Query: 650 IGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
G G + T+ VP ++ Q ++ + T++ + + + + + E
Sbjct: 508 WGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTE 567
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFT 758
+S + +++ + + GL Y LR A+N G ++ + T
Sbjct: 568 VSTGK----EQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDIT 614
Score = 48.4 bits (110), Expect = 1e-04
Identities = 61/286 (21%), Positives = 114/286 (39%), Gaps = 22/286 (7%)
Query: 470 ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR 529
++ V+ P D VP ++S R + W+ N + ++ G E L
Sbjct: 424 SSSVLPSAPRDVVPVLVSS--RFVRLSWRPPAEAKGN---IQTFTVFFSREGDNRERAL- 477
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPPI------LAV 581
N + G+L +++ YT V N G E + ++V P+ + L
Sbjct: 478 -NTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQA 536
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
V + S+ + W P+ GY + + E +E +E + L L T Y
Sbjct: 537 VSTSPTSILITWEPPAYANGPVQGYRL-FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYS 595
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WL-DSWGDGGCGI 698
L A+NR G G+ D + T VP P++ + +N+ ++ V WL G I
Sbjct: 596 LRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFI 655
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I +R+ ++ R +++ + +GL + Y +++A
Sbjct: 656 TGYKIRHRKTTR---RGEMETLEPNNLWYLFTGLEKGSQYSFQVSA 698
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 7/142 (4%)
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLP 478
+++++ D R++ L + H P +Q S LG+ + T
Sbjct: 79 IHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEAS----LGDSGSIISRTAKV 134
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL---ESTLRKNVSSD 535
+ + P R S + ++ + + L C +G P P W N L R V
Sbjct: 135 AVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS 194
Query: 536 GTLTISMTQSADSGNYTCSVEN 557
G L IS Q D G Y CS N
Sbjct: 195 GALQISRLQPGDIGIYRCSARN 216
Score = 35.9 bits (79), Expect = 0.80
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGN 550
N+V ++ L C G P P+ TW ++ +K ++ L IS DSG
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 307
Query: 551 YTCSVENIHGRDEVTYTVEVKVPP 574
YTC V + + + V VPP
Sbjct: 308 YTCVVTYKNENISASAELTVLVPP 331
Score = 35.9 bits (79), Expect = 0.80
Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 10/98 (10%)
Query: 73 PKNIRVIDQQS--RTIQISWTQPYAGNSPIINYIVQY---KEAP-ESWPSTPQKVIVPGS 126
PK+ VI ++ R + +SW P N I YI+ Y K P + W + G
Sbjct: 948 PKDFTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIME----TISGD 1003
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT 164
+ + +L T Y+ RI A N G S P+ T
Sbjct: 1004 RLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRT 1041
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 141 bits (342), Expect = 1e-32
Identities = 101/361 (27%), Positives = 163/361 (45%), Gaps = 32/361 (8%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
S +P P+++ + SR +++SW P I + V + ++ PG
Sbjct: 359 SSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN-RERALNTTQPG 417
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSST 184
S+ +V NL+P Y R++A N G E SQP++V T E+ GP ++++ + S T
Sbjct: 418 SL-QLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 476
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+++TWEPP NG + GY + E+++ I G SY
Sbjct: 477 SILITWEPPAYA--NGPVQGYRLFCTEVSTGKEQNIEVD--GLSYK-------------- 518
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+K Y++ AYN + DVPS PP + ++S+S++VSW
Sbjct: 519 -LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSW 577
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
PPP +NG + GY++ + T + T + + L +GL + + YS V A T
Sbjct: 578 LPPPSGTQNGFITGYKIRHRKTT---RRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMT 634
Query: 365 AAGDG------VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
G G P E VP P+ + + N I++SW PP +PN V+ GY
Sbjct: 635 VNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSWTPPLNPNIVVRGYI 693
Query: 419 L 419
+
Sbjct: 694 I 694
Score = 95.1 bits (226), Expect = 1e-18
Identities = 97/334 (29%), Positives = 139/334 (41%), Gaps = 40/334 (11%)
Query: 146 IAENRLGQSEPSQ----PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
+AEN G ++ S P + V P+DV SS + ++W PP GN
Sbjct: 335 VAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEA--KGN 392
Query: 202 ILGYYVGF-QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
I + V F +E ++ L + PG TV L+ A Y V
Sbjct: 393 IQTFTVFFSREGDNRERALNTTQPGSLQLTV---------------GNLKPEAMYTFRVV 437
Query: 261 AYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
AYN + VP P LQ + S S+ ++WEPP NG +QG
Sbjct: 438 AYNEWGPGESSQPIKVATQPELQVPG-PVENLQAVSTSPTSILITWEPPAYA--NGPVQG 494
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
YR+ V+ G E + ++ GL L GL+++T YS+ A+ G GV +
Sbjct: 495 YRLFCTEVST--GKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVV 550
Query: 379 TEEDVPSA-PADIKAAVSSRNKILVSWLPPSS--PNGVLVGYTL-YMSVIEDGREEGTHK 434
T DVPSA P ++ V + I VSWLPP S NG + GY + + G E
Sbjct: 551 TLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME---- 606
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
L P+ L + + + + F VSA T G G
Sbjct: 607 -TLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTG 639
Score = 82.2 bits (194), Expect = 9e-15
Identities = 92/394 (23%), Positives = 164/394 (41%), Gaps = 34/394 (8%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV-TKQI 340
+PS P + +SS+ VR+SW PP G +Q + V ++ D E A+ T Q
Sbjct: 362 LPSAPRDVVPV-LVSSRFVRLSWRPPAEA--KGNIQTFTVFFSREGD--NRERALNTTQP 416
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRN 398
L T+ L+ Y+ V A+ G G + P+ T+ + VP +++A +S
Sbjct: 417 GSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 476
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
IL++W PP+ NG + GY L+ + + G+E+ + LS++ +
Sbjct: 477 SILITWEPPAYANGPVQGYRLFCTEVSTGKEQN-----IEVDGLSYKLEGLKKFTEYSLR 531
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
A R G G +T +TV+ VP ++ +N+ + S+ + + P+
Sbjct: 532 FLAYNRYGPGVSTDDITVVTLSDVP---SAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGF 588
Query: 519 MNGVGL---ESTLRKNVSS--DGTLTISMTQSADSGNYTCSVE----NIHGRDEVTYTVE 569
+ G + ++T R + + L T Y+ V N G YT E
Sbjct: 589 ITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAE 648
Query: 570 V--------KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQ 621
+VP QP L V + + + W+ + + GY+I Y E ++
Sbjct: 649 TPENDLDESQVPDQPSSLH-VRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVR 707
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
V++ + + L + Y + + AFN G G+P
Sbjct: 708 VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVP 741
Score = 79.4 bits (187), Expect = 7e-14
Identities = 91/396 (22%), Positives = 155/396 (39%), Gaps = 29/396 (7%)
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
+PSAP D+ + S + +SW PP+ G + +T++ S D RE + P +L
Sbjct: 362 LPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQ--PGSL 419
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL--PSDSVPARITSFSRNIVTPWKEN 500
P A + F V A G GE+++ + V P VP + + +P
Sbjct: 420 QLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSIL 479
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCS--VENI 558
I+ P + + + + +N+ DG L+ + Y+ N
Sbjct: 480 ITWE-PPAYANGPVQGYRLFCTEVSTGKEQNIEVDG-LSYKLEGLKKFTEYSLRFLAYNR 537
Query: 559 HG----RDEVTYTVEVKVPPQPP---ILAVVDSYADSLHLQW--SDQGDGGSPILGYVIN 609
+G D++T VP PP L VV+S S+ + W G I GY I
Sbjct: 538 YGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSR--SIKVSWLPPPSGTQNGFITGYKIR 595
Query: 610 YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT------ 663
+++ E +E ++ L G++Y ++A GTG P + A T
Sbjct: 596 HRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLD 655
Query: 664 KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQAT 723
+ VP +P + + W + ++I Y + P V V +
Sbjct: 656 ESQVPDQPSSLHVRPQTNCIIMSWTPPLNPN-IVVRGYIIGYG-VGSPYAETVR--VDSK 711
Query: 724 ERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
+R +S+ L ++HY + + A NNAG + LY T
Sbjct: 712 QRYYSIERLESSSHYVISLKAFNNAGEGVPLYESAT 747
Score = 48.8 bits (111), Expect = 1e-04
Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 19/291 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTI 540
VP + N+ +I C G P P W NG V + S + V +
Sbjct: 263 VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL 322
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP--PQPPILA-----VVDSYADS--LHL 591
+ +S D G Y C EN G + + + V P P +L VV S + L
Sbjct: 323 GVVKS-DEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRL 381
Query: 592 QWSDQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITAFNR 649
W + I + + + RE + E + G+ + + NL Y + A+N
Sbjct: 382 SWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNE 441
Query: 650 IGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
G G + T+ VP ++ Q ++ + T++ + + + + + E
Sbjct: 442 WGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTE 501
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFT 758
+S + +++ + + GL Y LR A+N G ++ + T
Sbjct: 502 VSTGK----EQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDIT 548
Score = 48.4 bits (110), Expect = 1e-04
Identities = 61/286 (21%), Positives = 114/286 (39%), Gaps = 22/286 (7%)
Query: 470 ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR 529
++ V+ P D VP ++S R + W+ N + ++ G E L
Sbjct: 358 SSSVLPSAPRDVVPVLVSS--RFVRLSWRPPAEAKGN---IQTFTVFFSREGDNRERAL- 411
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPPI------LAV 581
N + G+L +++ YT V N G E + ++V P+ + L
Sbjct: 412 -NTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQA 470
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
V + S+ + W P+ GY + + E +E +E + L L T Y
Sbjct: 471 VSTSPTSILITWEPPAYANGPVQGYRL-FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYS 529
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WL-DSWGDGGCGI 698
L A+NR G G+ D + T VP P++ + +N+ ++ V WL G I
Sbjct: 530 LRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFI 589
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I +R+ ++ R +++ + +GL + Y +++A
Sbjct: 590 TGYKIRHRKTTR---RGEMETLEPNNLWYLFTGLEKGSQYSFQVSA 632
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 7/142 (4%)
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLP 478
+++++ D R++ L + H P +Q S LG+ + T
Sbjct: 13 IHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEAS----LGDSGSIISRTAKV 68
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL---ESTLRKNVSSD 535
+ + P R S + ++ + + L C +G P P W N L R V
Sbjct: 69 AVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS 128
Query: 536 GTLTISMTQSADSGNYTCSVEN 557
G L IS Q D G Y CS N
Sbjct: 129 GALQISRLQPGDIGIYRCSARN 150
Score = 41.1 bits (92), Expect = 0.021
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 12/160 (7%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + SR+I++SW P +G N I Y +++++
Sbjct: 544 TDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR-- 601
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSG 171
+ + P ++ L+ + Y ++ A G PS T E +
Sbjct: 602 -RGEMETLEPNNLWYL-FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQV 659
Query: 172 PPQDVRVEAKSSTE-LIVTWEPPQRD--LWNGNILGYYVG 208
P Q + + T +I++W PP + G I+GY VG
Sbjct: 660 PDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVG 699
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 141 bits (342), Expect = 1e-32
Identities = 105/372 (28%), Positives = 164/372 (44%), Gaps = 30/372 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 511 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 565
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 566 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 625
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 673
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 674 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 733
Query: 309 MRGRNGILQGYRVTYAPVTDWYGN-----EDAV-------TKQISGLHTTLSGLRRYTNY 356
++G ++GY+VTY + + +D + ++ TT+SGL T Y
Sbjct: 734 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTY 793
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
SVTV A+T GDG R+ P T VP P + + ++ N L+ W PP G L+G
Sbjct: 794 SVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNTALLQWHPPKELPGELLG 852
Query: 417 YTLYMSVIEDGR 428
Y L ++ R
Sbjct: 853 YRLQYCRADEAR 864
Score = 128 bits (310), Expect = 8e-29
Identities = 166/713 (23%), Positives = 286/713 (40%), Gaps = 67/713 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P ++ V + + ++ ++W +GNS P+ Y +QY+ A P + +
Sbjct: 318 LPKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQEVDGV---AT 371
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y R++A N +G+ PS+ V+ T E+ PS PP+ V+ S++ ++
Sbjct: 372 TRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTML 431
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WEPP+ NG + GY V + + P A + T G TT+
Sbjct: 432 VQWEPPEEP--NGLVRGYRVYYTPDSRR--------PPNAWHKHNTDAGL-----LTTVG 476
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y++ V A+ + + VP+ P Q S +++SW P
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLLP 535
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
P + I+ Y + Y D + VT + +T L L+ T Y + A + G
Sbjct: 536 P---QERIIM-YELVYWAAED-EDQQHKVTFDPTSSYT-LEDLKPDTLYRFQLAARSDMG 589
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVS-SRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
GV + T + PSAP VS + VSW+PP S NGV+ Y++ +
Sbjct: 590 VGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAV 649
Query: 425 EDGREEGTHK-RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG + G H +S S + ++ WV A T +G G + V V + V
Sbjct: 650 -DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 708
Query: 483 ---PARITSFSRN---IVTPWK-----------ENISLSCNKVGVPAPATTWTMNGVGL- 524
P ++ N + WK ++ ++ P + V L
Sbjct: 709 SGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA 768
Query: 525 ESTLRKNVSSDGTLTIS-----MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
E+ R S D TIS T S YT + + ++ T VP +P ++
Sbjct: 769 EAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA-VPGRPTMM 827
Query: 580 AVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGT 638
+ +L LQW + +LGY + Y R + + + L GT
Sbjct: 828 ISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGT 886
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS--WGDGGC 696
Y + A NR G G + + P++ + L T+T + D +
Sbjct: 887 TYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNG 946
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
I+ + + +R+++ Q + N T+ F+++GL P Y +++ A + G
Sbjct: 947 RIISYTVVFRDINSQQ--ELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKG 995
Score = 125 bits (301), Expect = 1e-27
Identities = 157/634 (24%), Positives = 255/634 (40%), Gaps = 63/634 (9%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V T + +P PP D+ V ++T + +TW D N + Y
Sbjct: 299 VAISSLGMIEATAQV---TVKALPK-PPIDLVVTETTATSVTLTW-----DSGNSEPVTY 349
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
Y G Q + + GP + V+G T +R ++ GL + YA V A NS
Sbjct: 350 Y-GIQYRAAGT-----EGP------FQEVDGVAT--TRYSIGGLSPFSEYAFRVLAVNSI 395
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAP 325
E PS PP +Q LS+ ++ V WEPP NG+++GYRV Y P
Sbjct: 396 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP--EEPNGLVRGYRVYYTP 453
Query: 326 VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
+ N +GL TT+ L YS+ V AFTA GDG + + T++ VP+
Sbjct: 454 DSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA 513
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
PAD +A V S +I +SWL P P ++ Y L ED E+ HK P T S+
Sbjct: 514 QPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAED--EDQQHKVTFDP-TSSYT 568
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWK 498
P ++F ++A + +G G T + + S P+ ++ S + W
Sbjct: 569 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 628
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL--TISMTQSADSGNYTCSVE 556
+ S N V ++G + +S + + + + + + + +
Sbjct: 629 PPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHT 688
Query: 557 NIHGRDE---VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINY 610
++ E V + VP PP V+ + ++H+ W I GY + Y
Sbjct: 689 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTY 748
Query: 611 KR-EHGDWEELQV--------------EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
R E+G+ L + E+ E + L T Y + + A+ G G
Sbjct: 749 VRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGAR 808
Query: 656 CDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRL 715
T G VP +P T T + W G +L + ++Y + +
Sbjct: 809 SKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPG-ELLGYRLQYCRADEARPNT 867
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ ++ F+V+GL Y R+ A N AG
Sbjct: 868 I--DFGKDDQHFTVTGLHKGTTYIFRLAAKNRAG 899
Score = 112 bits (270), Expect = 6e-24
Identities = 101/380 (26%), Positives = 156/380 (41%), Gaps = 19/380 (5%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 596 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 653
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 654 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 713
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNST--VLIASGPGGASYTVR 232
V VE +ST + V W+ P +G I GY V + L + + I A R
Sbjct: 714 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWR 773
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
E + TT+SGL Y+V V AY ++ VP P +
Sbjct: 774 PEE---SEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMIST 830
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
A++ + + W PP + G L GYR+ Y + N K H T++GL +
Sbjct: 831 TAMN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGLHK 884
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SS 409
T Y + A AG G T ED+PS P ++ + + ++W PP +
Sbjct: 885 GTTYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAE 943
Query: 410 PNGVLVGYTLYMSVIEDGRE 429
NG ++ YT+ I +E
Sbjct: 944 RNGRIISYTVVFRDINSQQE 963
Score = 85.8 bits (203), Expect = 8e-16
Identities = 77/313 (24%), Positives = 124/313 (39%), Gaps = 26/313 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++ W
Sbjct: 783 TISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LLQW 840
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP+ G +LGY + + + I G +TV +GL
Sbjct: 841 HPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TGLH 883
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
K Y + A N R ED+PS P L L++ + ++W+PP +
Sbjct: 884 KGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 942
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G G
Sbjct: 943 ERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGSGP 998
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIEDGR 428
+ + T + + A + + +L+SW P S + LY SV DG
Sbjct: 999 LSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGH 1058
Query: 429 EEGTHKRMLSPST 441
L P+T
Sbjct: 1059 SMRKLIADLQPNT 1071
Score = 82.2 bits (194), Expect = 9e-15
Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 12/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++L+C VG P P W M G E +++ G + ++ S NYTC +
Sbjct: 248 SVNLTCVAVGAPMPYVKWMM---GAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSL 304
Query: 560 GRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR--EHGD 616
G E T V VK P+PPI L V ++ A S+ L W D G+ P+ Y I Y+ G
Sbjct: 305 GMIEATAQVTVKALPKPPIDLVVTETTATSVTLTW-DSGN-SEPVTYYGIQYRAAGTEGP 362
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
++E+ A T+ + + L + Y + A N IG G P + V A T P P+ Q
Sbjct: 363 FQEVDGVA-TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQ 421
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ +T+ V W G Y V + +P ++ A + +V L P
Sbjct: 422 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDA-GLLTTVGSLLP 480
Query: 735 AAHYQLRITAHNNAG 749
Y LR+ A G
Sbjct: 481 GITYSLRVLAFTAVG 495
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 141 bits (342), Expect = 1e-32
Identities = 119/439 (27%), Positives = 190/439 (43%), Gaps = 34/439 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGS 126
P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W + PGS
Sbjct: 607 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSK---YPGS 663
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
V SA V L P +Y R+IA N +G S PS P + T+ P P DV+ E
Sbjct: 664 VNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 722
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW P G L Y V ++ + ++ TV G SR
Sbjct: 723 MEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG-----SRYV 766
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ + Y + VQA N ED P P ++ ++S ++ + W
Sbjct: 767 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 826
Query: 306 PPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVT 359
G L+ YR Y + + + + ++ G L +S L Y+NY +
Sbjct: 827 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 886
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ GDG R+ T E VPSAP + + I + W P PNG+++GYTL
Sbjct: 887 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 946
Query: 420 YMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA-TRVVTVL 477
V +G + G SP+ R+ P + ++F +SA T++G GEA T
Sbjct: 947 -KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAP 1005
Query: 478 PSDSVP-ARITSFSRNIVT 495
P+++ P A T+ +I T
Sbjct: 1006 PNEATPTAAYTNNQADIAT 1024
Score = 52.4 bits (120), Expect = 9e-06
Identities = 64/279 (22%), Positives = 99/279 (35%), Gaps = 18/279 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 515 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 573
Query: 541 SMTQSADSGNYTCSVENIHGRDEV-TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG 599
D G+YTC +D Y + P +P L + D S+ L W
Sbjct: 574 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 633
Query: 600 GSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
SPI YV+ ++ + G W + G+ + L YQ + A N +G+ P
Sbjct: 634 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 693
Query: 657 DIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGCGILYFVIEYREMSQP 711
Y P + + T W +++ G + Y V R ++
Sbjct: 694 LPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE 753
Query: 712 QWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
W N+V + V G TP Y++R+ A N+ G
Sbjct: 754 AW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 787
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 380 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 434
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 435 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 494
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 495 CVATNILGKAENQVRLEVKDP 515
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 257 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 316
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 317 GSIRHTISVRVKAAP 331
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 338 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 396
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 397 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 425
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/117 (23%), Positives = 44/117 (37%), Gaps = 7/117 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P+ RV TI + W P N +I Y ++Y + + T
Sbjct: 910 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 969
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+VQ P + Y + A ++G E TEE P+ P + A ++ +
Sbjct: 970 KFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPAPPNEATPTAAYTNNQ 1019
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 477 LPSD-SVPARITSFSR--NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+P D + P IT S +IV P ++NI + C G PAP+ WT N VS
Sbjct: 27 IPMDLTQPPTITKQSAKDHIVDP-RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 534 ---SDGTLTISMTQSAD----SGNYTCSVENIHG 560
GTL I G Y C N G
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 119
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 141 bits (342), Expect = 1e-32
Identities = 119/439 (27%), Positives = 190/439 (43%), Gaps = 34/439 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGS 126
P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W + PGS
Sbjct: 624 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSK---YPGS 680
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
V SA V L P +Y R+IA N +G S PS P + T+ P P DV+ E
Sbjct: 681 VNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 739
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW P G L Y V ++ + ++ TV G SR
Sbjct: 740 MEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG-----SRYV 783
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ + Y + VQA N ED P P ++ ++S ++ + W
Sbjct: 784 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 843
Query: 306 PPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVT 359
G L+ YR Y + + + + ++ G L +S L Y+NY +
Sbjct: 844 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 903
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ GDG R+ T E VPSAP + + I + W P PNG+++GYTL
Sbjct: 904 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 963
Query: 420 YMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA-TRVVTVL 477
V +G + G SP+ R+ P + ++F +SA T++G GEA T
Sbjct: 964 -KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAP 1022
Query: 478 PSDSVP-ARITSFSRNIVT 495
P+++ P A T+ +I T
Sbjct: 1023 PNEATPTAAYTNNQADIAT 1041
Score = 52.4 bits (120), Expect = 9e-06
Identities = 64/279 (22%), Positives = 99/279 (35%), Gaps = 18/279 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 532 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 590
Query: 541 SMTQSADSGNYTCSVENIHGRDEV-TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG 599
D G+YTC +D Y + P +P L + D S+ L W
Sbjct: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 650
Query: 600 GSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
SPI YV+ ++ + G W + G+ + L YQ + A N +G+ P
Sbjct: 651 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 710
Query: 657 DIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGCGILYFVIEYREMSQP 711
Y P + + T W +++ G + Y V R ++
Sbjct: 711 LPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE 770
Query: 712 QWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
W N+V + V G TP Y++R+ A N+ G
Sbjct: 771 AW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 804
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 397 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 451
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 452 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 511
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 512 CVATNILGKAENQVRLEVKDP 532
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 274 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 333
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 334 GSIRHTISVRVKAAP 348
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 413
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 414 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 442
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/117 (23%), Positives = 44/117 (37%), Gaps = 7/117 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P+ RV TI + W P N +I Y ++Y + + T
Sbjct: 927 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 986
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+VQ P + Y + A ++G E TEE P+ P + A ++ +
Sbjct: 987 KFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPAPPNEATPTAAYTNNQ 1036
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 477 LPSD-SVPARITSFSR--NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+P D + P IT S +IV P ++NI + C G PAP+ WT N VS
Sbjct: 27 IPMDLTQPPTITKQSAKDHIVDP-RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 534 ---SDGTLTISMTQSAD----SGNYTCSVENIHG 560
GTL I G Y C N G
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 119
>AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 variant
protein.
Length = 1130
Score = 140 bits (339), Expect = 3e-32
Identities = 162/638 (25%), Positives = 252/638 (39%), Gaps = 73/638 (11%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG-NSPIINYIVQYKEAPE 112
+ T D + + +P P+++ +R I+++W P + + + Y V Y +
Sbjct: 119 TSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGI 178
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SG 171
+ + PG + ++QNL PAT Y R++A+N+ G E S P++V T EV G
Sbjct: 179 ARERV-ENTSHPGEM-QVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPG 236
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
P ++R A S T + VTWE P NG I Y + + E ++
Sbjct: 237 PAPNLRAYAASPTSITVTWETPVSG--NGEIQNYKLYYMEKGTDKE-------------- 280
Query: 232 RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQ 291
+ + T++GL+K+ Y+ V AYN + DVPS P L
Sbjct: 281 ---QDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLS 337
Query: 292 CNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSG 349
+S+S+ + W+PP +NG + GY++ Y + D +SG L + G
Sbjct: 338 LEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKAS---RKSDVTETLVSGTQLSQLIEG 394
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHT------EEDVPSAPAD--IKAAVSSRNKIL 401
L R T Y+ V A T G G + T E VP P+ ++ V+S I+
Sbjct: 395 LDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTS---IV 451
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
VSW PP + N V+ GY + + T K + + P + + + A
Sbjct: 452 VSWTPPENQNIVVRGYAIGYGI--GSPHAQTIK--VDYKQRYYTIENLDPSSHYVITLKA 507
Query: 462 STRLGEG------EATRVVTV------LPSDSVPARITSFSRNIVTPWKENISLSCNKVG 509
+GEG TR TV +P V A I S +T W +N K+
Sbjct: 508 FNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRIT-WADNSLPKHQKIT 566
Query: 510 VPAPATT-WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
T W N +T KN ++ TL+ +T + Y SV GR T+++
Sbjct: 567 DSRYYTVRWKTNIPA--NTKYKNANAT-TLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSM 623
Query: 569 EVK------VPPQPPILAVV---DSYADSLHLQWSDQGDGGSPILGYVINY----KREHG 615
VP PP V + ++ + W + I GY+I Y E
Sbjct: 624 TAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIH 683
Query: 616 DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
DW V H + L T Y I A N G G
Sbjct: 684 DWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG 721
Score = 92.7 bits (220), Expect = 7e-18
Identities = 106/440 (24%), Positives = 174/440 (39%), Gaps = 51/440 (11%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + + S++I I W P N I Y ++Y++A S
Sbjct: 317 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKA--SR 374
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE------V 168
S + +V G+ S ++ L T Y+ R+ A G + + T E V
Sbjct: 375 KSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRV 434
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P + V T ++V+W PP+ N + GY +G+ G S
Sbjct: 435 PE-VPSSLHVRPLV-TSIVVSWTPPENQ--NIVVRGYAIGY---------------GIGS 475
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS---- 284
+T++ + T+ L + Y + ++A+N+ VP
Sbjct: 476 PHAQTIK-VDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPM 534
Query: 285 LPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLH 344
+PP +Q + LS ++R++W + I T W N A TK +
Sbjct: 535 MPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR----WKTNIPANTKYKNANA 590
Query: 345 TTLS----GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK- 399
TTLS GL+ T Y +V + + T E VP++P VS K
Sbjct: 591 TTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKP 650
Query: 400 --ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP---STLSHETSRSPPRAT 454
I+V+W PPS NG + GY +Y S D E H ++ P + L+H+
Sbjct: 651 KTIIVNWQPPSEANGKITGYIIYYST--DVNAE-IHDWVIEPVVGNRLTHQIQELTLDTP 707
Query: 455 HQFWVSASTRLGEGEATRVV 474
+ F + A G G + V
Sbjct: 708 YYFKIQARNSKGMGPMSEAV 727
Score = 69.7 bits (163), Expect = 5e-11
Identities = 113/512 (22%), Positives = 201/512 (39%), Gaps = 52/512 (10%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS 341
+PS P + + +S++ ++++W P L Y V Y + E
Sbjct: 134 LPSAPRDVV-ASLVSTRFIKLTWRTPASDPHGDNLT-YSVFYTK--EGIARERVENTSHP 189
Query: 342 G-LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV--PSAPADIKAAVSSRN 398
G + T+ L T Y V A G G +AP+ T+ +V P +++A +S
Sbjct: 190 GEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT 249
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQF 457
I V+W P S NG + Y LY E+GT K + S+ S+ + + F
Sbjct: 250 SITVTWETPVSGNGEIQNYKLYY------MEKGTDKEQDVDVSSHSYTINGLKKYTEYSF 303
Query: 458 WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-T 516
V A + G G +T V V VP ++ +N+ + + S+ + PAPAT
Sbjct: 304 RVVAYNKHGPGVSTPDVAVRTLSDVP---SAAPQNLSLEVRNSKSIMIH-WQPPAPATQN 359
Query: 517 WTMNGVGL---ESTLRKNVSS---DGTLTISMTQSADSG---NYTCSVENIHGRDEVTYT 567
+ G + +++ + +V+ GT + + D G N+ + I+G T
Sbjct: 360 GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDW 419
Query: 568 V----------EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
+ E +VP P L V S+ + W+ + + GY I Y
Sbjct: 420 LSAETFESDLDETRVPEVPSSLH-VRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHA 478
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP-----VKPK 672
+ ++V+ + + NL + Y + + AFN +G G+P TVP + P
Sbjct: 479 QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPV 538
Query: 673 HSQMITLNTTTVTV-WLDSWGDGGCGIL---YFVIEYREMSQPQWRLVSNSVQATERVFS 728
Q L+ T+ + W D+ I Y+ + ++ + + AT +
Sbjct: 539 GVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKY--KNANATTLSYL 596
Query: 729 VSGLTPAAHYQLRITAHNNAGHALALYNFTTH 760
V+GL P Y+ + G + ++ T H
Sbjct: 597 VTGLKPNTLYEFSVMV--TKGRRSSTWSMTAH 626
Score = 68.9 bits (161), Expect = 9e-11
Identities = 89/396 (22%), Positives = 154/396 (38%), Gaps = 26/396 (6%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSW-LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
T +PSAP D+ A++ S I ++W P S P+G + Y+++ + ++G +
Sbjct: 130 TTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT--KEGIARERVENTS 187
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV--LPSDSVPARITSFSRNIVT 495
P + P + F V A + G GE++ + V P +P + +
Sbjct: 188 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 247
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGTLTISMTQSADSGNYTCS 554
P ++ V + + + + ++V S + TI+ + ++
Sbjct: 248 PTSITVTWE-TPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVV 306
Query: 555 VENIHGRDEVTYTVEVK----VP---PQPPILAVVDSYADSLHLQWSDQGDGGSPILGYV 607
N HG T V V+ VP PQ L V +S + +H Q I GY
Sbjct: 307 AYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYK 366
Query: 608 INYKR--EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT-- 663
I Y++ D E V ++ L GT Y + A GTG D + A T
Sbjct: 367 IRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFE 426
Query: 664 ----KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
+ VP P + L T+ V W + + + I Y + P + +
Sbjct: 427 SDLDETRVPEVPSSLHVRPLVTSIVVSWTPP-ENQNIVVRGYAIGY-GIGSPHAQTI--K 482
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
V +R +++ L P++HY + + A NN G + LY
Sbjct: 483 VDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLY 518
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 73 PKNIRVIDQQSR--TIQISWTQPYAGNSPIINYIVQYKEAPES----WPSTPQKVIVPGS 126
PK++ V+ ++ + TI ++W P N I YI+ Y + W P V G+
Sbjct: 638 PKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP----VVGN 693
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
+ +Q L T Y+ +I A N G S+ VQ T + SG
Sbjct: 694 RLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKASGSG 738
Score = 39.5 bits (88), Expect = 0.065
Identities = 63/293 (21%), Positives = 104/293 (35%), Gaps = 40/293 (13%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTISMTQSADSGN 550
NI +I C G P P W NG + + S K V + + +S D G
Sbjct: 25 NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKS-DEGF 83
Query: 551 YTCSVENIHGRDE-----VTYTVEVKVPPQPP---ILAVVDSYADS-------------- 588
Y C EN G + + +V +P PP A D A +
Sbjct: 84 YQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVA 143
Query: 589 -------LHLQW-SDQGDGGSPILGYVINYKREHGDWEELQ--VEAGTSEHVLPNLWCGT 638
+ L W + D L Y + Y +E E ++ G + + NL T
Sbjct: 144 SLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPAT 203
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGC 696
Y + A N+ G+G + T+ V P + + + T++TV ++ G
Sbjct: 204 VYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNG 263
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
I + + Y E + V + ++++GL Y R+ A+N G
Sbjct: 264 EIQNYKLYYMEKGTDK----EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 312
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 140 bits (338), Expect = 3e-32
Identities = 105/372 (28%), Positives = 163/372 (43%), Gaps = 30/372 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 501 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 555
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 556 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 615
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V + ++ G V+G S L G
Sbjct: 616 SWVPPPADSRNGVITQYSVAHEAVD------------GEDRGRHVVDGISREHSSWDLVG 663
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 664 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 723
Query: 309 MRGRNGILQGYRVTYAPVTDWYGN-----EDAV-------TKQISGLHTTLSGLRRYTNY 356
++G ++GY+VTY + + +D + ++ TT+SGL T Y
Sbjct: 724 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTY 783
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
SVTV A+T GDG R+ P T VP P + + ++ N L+ W PP G L+G
Sbjct: 784 SVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNTALLQWHPPKELPGELLG 842
Query: 417 YTLYMSVIEDGR 428
Y L ++ R
Sbjct: 843 YRLQYCRADEAR 854
Score = 128 bits (309), Expect = 1e-28
Identities = 166/713 (23%), Positives = 286/713 (40%), Gaps = 67/713 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P ++ V + + ++ ++W +GNS P+ Y +QY+ A P + +
Sbjct: 308 LPKPPIDLVVTETTATSVTLTWD---SGNSEPVTYYGIQYRAAGTEGPFQEVDGV---AT 361
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y R++A N +G+ PS+ V+ T E+ PS PP+ V+ S++ ++
Sbjct: 362 TRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTML 421
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WEPP+ NG + GY V + + P A + T G TT+
Sbjct: 422 VQWEPPEEP--NGLVRGYRVYYTPDSRR--------PPNAWHKHNTDAGL-----LTTVG 466
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y++ V A+ + + VP+ P Q S +++SW P
Sbjct: 467 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA-QPADFQAEVESDTRIQLSWLLP 525
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
P + I+ Y + Y D + VT + +T L L+ T Y + A + G
Sbjct: 526 P---QERIIM-YELVYWAAED-EDQQHKVTFDPTSSYT-LEDLKPDTLYRFQLAARSDMG 579
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVS-SRNKILVSWLPP--SSPNGVLVGYTLYMSVI 424
GV + T + PSAP VS + VSW+PP S NGV+ Y++ +
Sbjct: 580 VGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAHEAV 639
Query: 425 EDGREEGTHK-RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV- 482
DG + G H +S S + ++ WV A T +G G + V V + V
Sbjct: 640 -DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 698
Query: 483 ---PARITSFSRN---IVTPWK-----------ENISLSCNKVGVPAPATTWTMNGVGL- 524
P ++ N + WK ++ ++ P + V L
Sbjct: 699 SGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA 758
Query: 525 ESTLRKNVSSDGTLTIS-----MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
E+ R S D TIS T S YT + + ++ T VP +P ++
Sbjct: 759 EAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA-VPGRPTMM 817
Query: 580 AVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGT 638
+ +L LQW + +LGY + Y R + + + L GT
Sbjct: 818 ISTTAMNTAL-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGT 876
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS--WGDGGC 696
Y + A NR G G + + P++ + L T+T + D +
Sbjct: 877 TYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNG 936
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
I+ + + +R+++ Q + N T+ F+++GL P Y +++ A + G
Sbjct: 937 RIISYTVVFRDINSQQ--ELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKG 985
Score = 125 bits (301), Expect = 1e-27
Identities = 157/634 (24%), Positives = 255/634 (40%), Gaps = 63/634 (9%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V T + +P PP D+ V ++T + +TW D N + Y
Sbjct: 289 VAISSLGMIEATAQV---TVKALPK-PPIDLVVTETTATSVTLTW-----DSGNSEPVTY 339
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
Y G Q + + GP + V+G T +R ++ GL + YA V A NS
Sbjct: 340 Y-GIQYRAAGT-----EGP------FQEVDGVAT--TRYSIGGLSPFSEYAFRVLAVNSI 385
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAP 325
E PS PP +Q LS+ ++ V WEPP NG+++GYRV Y P
Sbjct: 386 GRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP--EEPNGLVRGYRVYYTP 443
Query: 326 VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
+ N +GL TT+ L YS+ V AFTA GDG + + T++ VP+
Sbjct: 444 DSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPA 503
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
PAD +A V S +I +SWL P P ++ Y L ED E+ HK P T S+
Sbjct: 504 QPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAED--EDQQHKVTFDP-TSSYT 558
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR-------ITSFSRNIVTPWK 498
P ++F ++A + +G G T + + S P+ ++ S + W
Sbjct: 559 LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWV 618
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL--TISMTQSADSGNYTCSVE 556
+ S N V ++G + +S + + + + + + + +
Sbjct: 619 PPPADSRNGVITQYSVAHEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHT 678
Query: 557 NIHGRDE---VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINY 610
++ E V + VP PP V+ + ++H+ W I GY + Y
Sbjct: 679 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTY 738
Query: 611 KR-EHGDWEELQV--------------EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
R E+G+ L + E+ E + L T Y + + A+ G G
Sbjct: 739 VRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGAR 798
Query: 656 CDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRL 715
T G VP +P T T + W G +L + ++Y + +
Sbjct: 799 SKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPG-ELLGYRLQYCRADEARPNT 857
Query: 716 VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ ++ F+V+GL Y R+ A N AG
Sbjct: 858 I--DFGKDDQHFTVTGLHKGTTYIFRLAAKNRAG 889
Score = 112 bits (270), Expect = 6e-24
Identities = 103/382 (26%), Positives = 162/382 (42%), Gaps = 23/382 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPS 116
T++ R + P P+ + + S T+++SW P A + + I QY A E+
Sbjct: 586 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGV--ITQYSVAHEAVDG 641
Query: 117 TPQ-KVIVPG---SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP 172
+ + +V G +S + L+ T Y + + A +G S PV V T E+VPSGP
Sbjct: 642 EDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGP 701
Query: 173 PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNST--VLIASGPGGASYT 230
P+ V VE +ST + V W+ P +G I GY V + L + + I A
Sbjct: 702 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 761
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL 290
R E + TT+SGL Y+V V AY ++ VP P +
Sbjct: 762 WRPEE---SEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMI 818
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGL 350
A++ + + W PP + G L GYR+ Y + N K H T++GL
Sbjct: 819 STTAMN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVTGL 872
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP-- 407
+ T Y + A AG G T ED+PS P ++ + + ++W PP
Sbjct: 873 HKGTTYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVL 931
Query: 408 SSPNGVLVGYTLYMSVIEDGRE 429
+ NG ++ YT+ I +E
Sbjct: 932 AERNGRIISYTVVFRDINSQQE 953
Score = 85.8 bits (203), Expect = 8e-16
Identities = 77/313 (24%), Positives = 124/313 (39%), Gaps = 26/313 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++ W
Sbjct: 773 TISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LLQW 830
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP+ G +LGY + + + I G +TV +GL
Sbjct: 831 HPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TGLH 873
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
K Y + A N R ED+PS P L L++ + ++W+PP +
Sbjct: 874 KGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 932
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G G
Sbjct: 933 ERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGSGP 988
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIEDGR 428
+ + T + + A + + +L+SW P S + LY SV DG
Sbjct: 989 LSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGH 1048
Query: 429 EEGTHKRMLSPST 441
L P+T
Sbjct: 1049 SMRKLIADLQPNT 1061
Score = 82.2 bits (194), Expect = 9e-15
Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 12/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++L+C VG P P W M G E +++ G + ++ S NYTC +
Sbjct: 238 SVNLTCVAVGAPMPYVKWMM---GAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSL 294
Query: 560 GRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR--EHGD 616
G E T V VK P+PPI L V ++ A S+ L W D G+ P+ Y I Y+ G
Sbjct: 295 GMIEATAQVTVKALPKPPIDLVVTETTATSVTLTW-DSGN-SEPVTYYGIQYRAAGTEGP 352
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
++E+ A T+ + + L + Y + A N IG G P + V A T P P+ Q
Sbjct: 353 FQEVDGVA-TTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQ 411
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ +T+ V W G Y V + +P ++ A + +V L P
Sbjct: 412 ARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDA-GLLTTVGSLLP 470
Query: 735 AAHYQLRITAHNNAG 749
Y LR+ A G
Sbjct: 471 GITYSLRVLAFTAVG 485
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 138 bits (335), Expect = 8e-32
Identities = 112/412 (27%), Positives = 178/412 (43%), Gaps = 32/412 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGS 126
P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W + PGS
Sbjct: 421 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSK---YPGS 477
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
V SA V L P +Y R+IA N +G S PS P + T+ P P DV+ E
Sbjct: 478 VNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 536
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW P G L Y V ++ + ++ TV G SR
Sbjct: 537 MEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG-----SRYV 580
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ + Y + VQA N ED P P ++ ++S ++ + W
Sbjct: 581 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 640
Query: 306 PPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVT 359
G L+ YR Y + + + + ++ G L +S L Y+NY +
Sbjct: 641 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 700
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ GDG R+ T E VPSAP + + I + W P PNG+++GYTL
Sbjct: 701 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 760
Query: 420 YMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 761 -KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 811
Score = 52.4 bits (120), Expect = 9e-06
Identities = 64/279 (22%), Positives = 99/279 (35%), Gaps = 18/279 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 329 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 387
Query: 541 SMTQSADSGNYTCSVENIHGRDEV-TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG 599
D G+YTC +D Y + P +P L + D S+ L W
Sbjct: 388 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 447
Query: 600 GSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
SPI YV+ ++ + G W + G+ + L YQ + A N +G+ P
Sbjct: 448 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 507
Query: 657 DIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGCGILYFVIEYREMSQP 711
Y P + + T W +++ G + Y V R ++
Sbjct: 508 LPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE 567
Query: 712 QWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
W N+V + V G TP Y++R+ A N+ G
Sbjct: 568 AW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 601
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 194 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 248
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 249 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 308
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 309 CVATNILGKAENQVRLEVKDP 329
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 71 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 130
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 131 GSIRHTISVRVKAAP 145
Score = 38.3 bits (85), Expect = 0.15
Identities = 29/112 (25%), Positives = 43/112 (38%), Gaps = 8/112 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P+ RV TI + W P N +I Y ++Y + + T
Sbjct: 724 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 783
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
+VQ P + Y + A ++G E TEE P+ PP + R A
Sbjct: 784 KFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPA-PPNEGRCMA 827
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 152 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 210
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 211 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 239
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 138 bits (335), Expect = 8e-32
Identities = 112/412 (27%), Positives = 178/412 (43%), Gaps = 32/412 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPSTPQKVIVPGS 126
P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W + PGS
Sbjct: 677 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSK---YPGS 733
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
V SA V L P +Y R+IA N +G S PS P + T+ P P DV+ E
Sbjct: 734 VNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 792
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW P G L Y V ++ + ++ TV G SR
Sbjct: 793 MEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG-----SRYV 836
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ + Y + VQA N ED P P ++ ++S ++ + W
Sbjct: 837 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 896
Query: 306 PPPMRGRNGILQGYRVTY----APVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVT 359
G L+ YR Y + + + + ++ G L +S L Y+NY +
Sbjct: 897 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 956
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ GDG R+ T E VPSAP + + I + W P PNG+++GYTL
Sbjct: 957 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 1016
Query: 420 YMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 1017 -KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 1067
Score = 52.4 bits (120), Expect = 9e-06
Identities = 64/279 (22%), Positives = 99/279 (35%), Gaps = 18/279 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 585 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 643
Query: 541 SMTQSADSGNYTCSVENIHGRDEV-TYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG 599
D G+YTC +D Y + P +P L + D S+ L W
Sbjct: 644 FGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDAN 703
Query: 600 GSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
SPI YV+ ++ + G W + G+ + L YQ + A N +G+ P
Sbjct: 704 NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 763
Query: 657 DIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGCGILYFVIEYREMSQP 711
Y P + + T W +++ G + Y V R ++
Sbjct: 764 LPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE 823
Query: 712 QWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
W N+V + V G TP Y++R+ A N+ G
Sbjct: 824 AW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 857
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 450 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 504
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 505 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 564
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 565 CVATNILGKAENQVRLEVKDP 585
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 327 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 386
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 387 GSIRHTISVRVKAAP 401
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 408 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 466
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 467 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 495
Score = 37.1 bits (82), Expect = 0.35
Identities = 26/104 (25%), Positives = 39/104 (37%), Gaps = 7/104 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P+ RV TI + W P N +I Y ++Y + + T
Sbjct: 980 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 1039
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP 172
+VQ P + Y + A ++G E TEE P+ P
Sbjct: 1040 KFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPAPP 1076
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 477 LPSD-SVPARITSFSR--NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+P D + P IT S +IV P ++NI + C G PAP+ WT N VS
Sbjct: 80 IPMDLTQPPTITKQSAKDHIVDP-RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 138
Query: 534 ---SDGTLTISMTQSAD----SGNYTCSVENIHG 560
GTL I G Y C N G
Sbjct: 139 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFG 172
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 137 bits (331), Expect = 2e-31
Identities = 115/413 (27%), Positives = 182/413 (44%), Gaps = 32/413 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY---KEAPESWPSTPQKVIVPG 125
VP+ P+N+ + ++Q+R+++++W NS I YIV++ KE P W + V G
Sbjct: 611 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTR---VQG 667
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSST 184
T+ + L P Y R+IA N +G+S+PSQP T P PQ++RV+A
Sbjct: 668 KKTTV-ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 726
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
E+I+ WEP + NG L Y V ++ P GA V E T +
Sbjct: 727 EMIIKWEPLKSMEQNGPGLEYRVTWK-------------PQGA--PVEWEEETVTNHTLR 771
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++ +A Y V VQA N ED P P + ++S V+V+W
Sbjct: 772 VMTP-AVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTW 830
Query: 305 EPPPMRGRNGILQGYRVTY---APVTDWYGNEDAVT-KQISGLHTT--LSGLRRYTNYSV 358
P +G L+GY++ + + D + V + SG + + L ++ + +
Sbjct: 831 STVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHL 890
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
TV A+ + G G + P T E VP P +K ++ +SW P NG L GY
Sbjct: 891 TVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYL 950
Query: 419 LYMSVIEDGREEG--THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L +I D E G + +PS S S ++F++ A T G G+
Sbjct: 951 LQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1003
Score = 62.1 bits (144), Expect = 1e-08
Identities = 68/248 (27%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 516 TWTMNGVGLE--STLRKNVSSDGT-LTISMTQSADSGNYTCSVEN-IHGRDEVTYTVEVK 571
+W+ +G E T + DG LTIS D G Y CS + ++T +
Sbjct: 551 SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLD 610
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINY---KREHGDWEELQVEAGTSE 628
VP P L + + S+ L W D S I Y++ + K E G WEEL G
Sbjct: 611 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKT 670
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCD-IVHAYTKGTVPVK-PKHSQMITLNTTTVTV 686
V+ L RYQ + A N +G P H T P + P++ ++ + +
Sbjct: 671 TVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMII 730
Query: 687 -W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA--AHYQLR 741
W L S G G +EYR +PQ V + T ++ +TPA A Y ++
Sbjct: 731 KWEPLKSMEQNGPG-----LEYRVTWKPQGAPVEWE-EETVTNHTLRVMTPAVYAPYDVK 784
Query: 742 ITAHNNAG 749
+ A N G
Sbjct: 785 VQAINQLG 792
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/89 (30%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 488 SFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
S S + +T K E + L C G+P P W G L + TL I
Sbjct: 244 SGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGKTLKIENVSYQ 303
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D GNY C+ N G + V V+ PP+
Sbjct: 304 DKGNYRCTASNFLGTATHDFHVIVEEPPR 332
Score = 40.7 bits (91), Expect = 0.028
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTL 538
D P T N T + L C P +W + V R ++ +GTL
Sbjct: 420 DVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTL 479
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
I+ T D+G+Y+C VEN G+ VT ++++
Sbjct: 480 QINRTTEEDAGSYSCWVENAIGKTAVTANLDIR 512
Score = 38.3 bits (85), Expect = 0.15
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 7/205 (3%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L + ++SVR++WE N + Y V + + G + +T+
Sbjct: 610 DVPD-PPENLHLSERQNRSVRLTWEAG--ADHNSNISEYIVEFEGNKEEPGRWEELTRVQ 666
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH-TEEDVPSA-PADIKAAVSSRN 398
T + L + Y V A G + P H T P P +I+ S
Sbjct: 667 GKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 726
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
++++ W P S G ++ G + ++ TL T A +
Sbjct: 727 EMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMT--PAVYAPYDVK 784
Query: 459 VSASTRLGEGEATRVVTVLPSDSVP 483
V A +LG G + VT+ + P
Sbjct: 785 VQAINQLGSGPDPQSVTLYSGEDYP 809
Score = 34.7 bits (76), Expect = 1.8
Identities = 31/126 (24%), Positives = 49/126 (38%), Gaps = 3/126 (2%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP--STPQKVIVPGS 126
VPE P ++VI T +SW P N + Y++QY+ +++ I S
Sbjct: 915 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 974
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
S + NL T Y + A G +P + +T E G + V T
Sbjct: 975 KPSWHLSNLNATTKYKFYLRACTSQGCGKPITE-ESSTLGEGSKGIGKISGVNLTQKTHP 1033
Query: 187 IVTWEP 192
+ +EP
Sbjct: 1034 VEVFEP 1039
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-----REHGDWEELQVEAGT 626
VP QP L V+ D+ L W + GY++ Y+ E G+ ++ + +
Sbjct: 915 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 974
Query: 627 --SEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
S H L NL T+Y+ Y+ A G G P
Sbjct: 975 KPSWH-LSNLNATTKYKFYLRACTSQGCGKP 1004
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 468 GEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES- 526
G AT V+ + P R T ++ V N L C G P P W +NG +++
Sbjct: 317 GTATHDFHVIVEE--PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNH 374
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+V ++ + Q + Y C N+HG
Sbjct: 375 PFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 408
Score = 33.1 bits (72), Expect = 5.6
Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 9/146 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I + P+ E + C G P P +WT +G T + + S+ + T
Sbjct: 34 VPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFR 93
Query: 542 MTQ----SADSGNYTCSVENIHG---RDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQW 593
+ S G Y C N G +E+ + V V P+ I + D + L
Sbjct: 94 IPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP- 152
Query: 594 SDQGDGGSPILGYVINYKREHGDWEE 619
+ G P+ Y +N + EH + +E
Sbjct: 153 CNPPKGLPPLHIYWMNIELEHIEQDE 178
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 137 bits (331), Expect = 2e-31
Identities = 161/666 (24%), Positives = 272/666 (40%), Gaps = 61/666 (9%)
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
E+ P + + + TS + + +I+ +N+ G++E ++V +VP G
Sbjct: 13963 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVI---DVP-G 14018
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
P +++ V E+ + WE P D I+GY V +++ + VL +TV
Sbjct: 14019 PVRNLEVTETFDGEVSLAWEEPLTD-GGSKIIGYVVERRDIKRKTWVLATDRAESCEFTV 14077
Query: 232 RTVEGAGTARSRTTLSGLQKHAA-YAVVVQAYN---SRXXXXXXXXXXXXXMEDVPSLPP 287
+GLQK Y V A N + DVP PP
Sbjct: 14078 ---------------TGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPG-PP 14121
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHT 345
+ ++ V ++WEPP G + Y + T W + A+T + L
Sbjct: 14122 LNVTITDVNRFGVSLTWEPPEYDG-GAEITNYVIELRDKTSIRW---DTAMTVRAEDLSA 14177
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV-RAAPVYCHTEEDV--PSAPADIKAAVSSRNKILV 402
T++ + YS V A G G AA + + + PS P ++ ++ +++ + +
Sbjct: 14178 TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQL 14237
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
W PP G ++GY + E+G++ M L+++ + + + VSA
Sbjct: 14238 KWEPPLKDGGSPILGYIIERC--EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSA 14295
Query: 462 STRLGEGEATRVVTVLPSDSV---PAR-ITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ G + + ++ L +D P +++F + I++ G P P TW
Sbjct: 14296 ENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATW 14355
Query: 518 TMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV-- 572
LE+ R K +S+ L IS ++ +D G YT +EN ++ ++V V
Sbjct: 14356 CFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLEN--RVKTISGEIDVNVIA 14413
Query: 573 -PPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSE 628
P P L D DS+HL W DGGSP+ GYV+ KRE W ++ E
Sbjct: 14414 RPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE-KREVSRKTWTKVMDFVTDLE 14472
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQM--ITLNTTT 683
+P+L G Y + A N+ G G P + V+ T TVP P++ + T N+
Sbjct: 14473 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIF 14532
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
+T W DGG I +++E +W V T+ V+GL Y R+
Sbjct: 14533 LT-WDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETK--MEVTGLEEGKWYAYRVK 14589
Query: 744 AHNNAG 749
A N G
Sbjct: 14590 ALNRQG 14595
Score = 134 bits (323), Expect = 2e-30
Identities = 167/663 (25%), Positives = 267/663 (40%), Gaps = 51/663 (7%)
Query: 111 PESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS 170
P + + K++V + T Q+ + T + I A N LG + + V P
Sbjct: 17090 PVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT-ITAVNNLGTASKEMRLNVLGRPGPPV 17148
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
GP ++ E+ S+ ++ ++W PP+ D I Y + +E N + V ++S P +YT
Sbjct: 17149 GP---IKFESVSADQMTLSWFPPKDD-GGSKITNYVIEKREANRKTWVHVSSEPKECTYT 17204
Query: 231 V-RTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA 289
+ + +EG + ++ Q + VP P
Sbjct: 17205 IPKLLEG--------------HEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKP 17250
Query: 290 LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISGLHTT 346
++++ S+ V+WE P G + + GY + T W N D + G+
Sbjct: 17251 T-VSSVTRNSMTVNWEEPEYDGGSPVT-GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYK 17308
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSW 404
++GL ++Y V A AAG G + P T D P P K +++ + W
Sbjct: 17309 VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEW 17368
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
PP G V GY + E+G+EE + + A ++F VSA
Sbjct: 17369 SPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVN 17426
Query: 464 RLGEGEATRVVTVLPSD----SVPARITSFSRN-IVTPWKENISLSCNKVGVPAPATTWT 518
G GE V V+ S ++ + R+ IV I + G P P TW
Sbjct: 17427 IAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWN 17486
Query: 519 MNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP 576
MN L E+T+ S ++ I Q + G Y+ +N G + T V+V P P
Sbjct: 17487 MNERTLPQEATIETTAIS-SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGP 17545
Query: 577 ---PILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVL 631
P LA + +S L W S + DGGSPI YVI + + W + +
Sbjct: 17546 VGTPFLA-HNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATV 17604
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQM--ITLNTTTVTV 686
L G Y I A N IG G + A TVP +P+ ++ +T NT T+T
Sbjct: 17605 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLT- 17663
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W DGG I+ +V+E R + ++ V+N R ++V GL Y+ R++A N
Sbjct: 17664 WNPPKYDGGSEIINYVLESRLIGTEKFHKVTND-NLLSRKYTVKGLKEGDTYEYRVSAVN 17722
Query: 747 NAG 749
G
Sbjct: 17723 IVG 17725
Score = 132 bits (318), Expect = 9e-30
Identities = 161/707 (22%), Positives = 288/707 (40%), Gaps = 64/707 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
+P P +++D TI I+W +P + G +PI Y V+YK++ ++ W ++ Q +
Sbjct: 27010 LPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL----R 27065
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T ++ L Y R+ + N++G S+PS +E P D+ E + + L
Sbjct: 27066 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKT--L 27123
Query: 187 IV------TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
IV T P R N+L + + + + + S T+ +
Sbjct: 27124 IVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSG 27180
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ T+ + A+ +VV+ D P PP + ++ +S
Sbjct: 27181 KYTLTIQNVLSAASLTLVVKVL------------------DTPG-PPTNITVQDVTKESA 27221
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
+SW+ P G ++ Y + + W +VT + L ++ L+ Y
Sbjct: 27222 VLSWDVPENDG-GAPVKNYHIEKREASKKAWV----SVTNNCNRLSYKVTNLQEGAIYYF 27276
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V G G+ A + PS P + S++ + ++WL P G + +
Sbjct: 27277 RVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHY 27336
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VL 477
+ + +E G++ K ++ ST H S + + F V A + G + ++ VL
Sbjct: 27337 V-VEALEKGQKNWV-KCAVAKST-HHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 27393
Query: 478 PSDSV-PARIT--SF-SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+ + P I +F S + N+ + G P P T + +GV L++T+R N
Sbjct: 27394 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 27453
Query: 534 SDG-TLTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADS 588
LTI++ +S AD+G Y + N G + + V P PP VV D +S
Sbjct: 27454 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 27513
Query: 589 LHLQWS-DQGDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
+ L+W + DGGS + Y++ KRE W E+ + + L G YQ I
Sbjct: 27514 VTLKWEPPKYDGGSQVTNYIL-LKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIK 27572
Query: 646 AFNRIGTGLPCDIVHAYTK--GTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFV 702
A NR G D K T P P + + ++TV W + +GG ++ +
Sbjct: 27573 AENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYH 27632
Query: 703 IEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E ++ + W+ + V T F V+ ++ Y+ R+ A N AG
Sbjct: 27633 LEMKDRNSILWQKANKLVIRTTH-FKVTTISAGLIYEFRVYAENAAG 27678
Score = 128 bits (309), Expect = 1e-28
Identities = 162/706 (22%), Positives = 281/706 (39%), Gaps = 54/706 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P V D +++++WT+P + G + I +Y+++ K + W + V
Sbjct: 14911 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV----PT 14966
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSSTE 185
T + L Y R+ A N+ G+SEPS+P E P PP+ + V +
Sbjct: 14967 TQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 15026
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ W P++D I Y V +++ + + TV+ ++ T
Sbjct: 15027 ADLKWTVPEKD-GGSPITNYIVEKRDVRRKGWQTVDT-------TVKD--------TKCT 15070
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCNALSSQSVRVS 303
++ L + + Y V A N+ +D + P P AL ++ + V +
Sbjct: 15071 VTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLK 15130
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVC 361
WEPP G I Q Y + + G + +G + ++ + T V
Sbjct: 15131 WEPPKNDGGRPI-QRYVIEKK---ERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVR 15186
Query: 362 AFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGY 417
A AG G + P + ED PS P D+ + R I ++W PP G ++GY
Sbjct: 15187 AENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 15246
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV---V 474
+ M + + + R + E P + + V A +G E + + V
Sbjct: 15247 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK-EYVLRVRAVNAIGVSEPSEISENV 15305
Query: 475 TVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS 534
D P I + +I+ E +S+ VP P +W +G ++++ R + +
Sbjct: 15306 VAKDPDCKPT-IDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN 15364
Query: 535 D---GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP-PILAVVDSYADSLH 590
D L + + AD+G YT ++EN G + V+V P P + D S
Sbjct: 15365 DHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCK 15424
Query: 591 LQWS-DQGDGGSPILGYVINYKREHGDWEELQVEAGTSE--HVLPNLWCGTRYQLYITAF 647
L W + DGG+PIL YV+ +RE G + V +G ++ + +L Y + A
Sbjct: 15425 LTWEPPEFDGGTPILHYVLE-RREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 15483
Query: 648 NRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVI 703
N++G G ++ V A P P ++ +T+ W DGG I+ ++I
Sbjct: 15484 NKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYII 15543
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
E + +W+ N ++ GL YQ R+ A N AG
Sbjct: 15544 EKIAKGEERWKR-CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 15588
Score = 128 bits (309), Expect = 1e-28
Identities = 164/708 (23%), Positives = 278/708 (39%), Gaps = 64/708 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P IR+ D +I + W++P Y G S + Y+V+ ++ E W + K V
Sbjct: 28094 PGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV--RT 28151
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ------SEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T V NL+P +Y+ R+ A N GQ +EP Q + E+ V AK
Sbjct: 28152 TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAK 28211
Query: 182 SSTELIVT----WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
+ ++ V PP W + + L S++ I + + T+ V
Sbjct: 28212 AGEDVQVLIPFKGRPPPTVTWRKDE-------KNLGSDARYSIENTDSSSLLTIPQVTRN 28264
Query: 238 GTARSRTTL-SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
T + T+ +G+ + + V V+ D P+ LQ +S
Sbjct: 28265 DTGKYILTIENGVGEPKSSTVSVKVL------------------DTPAACQ-KLQVKHVS 28305
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+V + W+PP + G + I+ Y + T V+ + S L L T +
Sbjct: 28306 RGTVTLLWDPPLIDGGSPIIN-YVIEKRDATK--RTWSVVSHKCSSTSFKLIDLSEKTPF 28362
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V A G G +VP+ D+ S++ +++SW P G ++
Sbjct: 28363 FFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVI- 28421
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
T Y+ V G+ E T T E S+ ++ +F V A G + + +
Sbjct: 28422 -TEYV-VERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 28479
Query: 477 LPSDSVPARITSFS----RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKN 531
+ + S + N+ L G P P+ +W +G+ L ES +
Sbjct: 28480 TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 28539
Query: 532 VSSDGTLTISM--TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYAD 587
++ +T+S+ + G YT ++N R V TV PP P + + AD
Sbjct: 28540 SKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKAD 28599
Query: 588 SLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S+ L W + +GG I Y I KRE +W+ + + +PNL YQ +
Sbjct: 28600 SVILSWDVPEDNGGGEITCYSIE-KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRV 28658
Query: 645 TAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYF 701
A NR G P I+ A + +P P + + + +++ W DGG + F
Sbjct: 28659 RAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGF 28718
Query: 702 VIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+E +E + W+ V N+ + R + +GL YQ R+ A N+AG
Sbjct: 28719 HVEKKERNSILWQKV-NTSPISGREYRATGLVEGLDYQFRVYAENSAG 28765
Score = 127 bits (307), Expect = 2e-28
Identities = 179/723 (24%), Positives = 284/723 (39%), Gaps = 63/723 (8%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES- 113
+TV + I L P P IR+ + +I ISW P Y G I NYIV+ KE +
Sbjct: 26403 ITVPITIIVLDRPGPPGP--IRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT 26460
Query: 114 WPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGP 172
W Q V + TS + L + Y R+ AENR G+S S+ V P GP
Sbjct: 26461 WHIVSQAV----ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGP 26516
Query: 173 PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR 232
P +V + + ++VTW+ P D ++GY++ ++E S++L + A+ +
Sbjct: 26517 PGTPKVVHATKSTMLVTWQVPVND-GGSRVIGYHLEYKE---RSSILWSK----ANKIL- 26567
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC 292
A ++ +SGL + Y V A N D P PPG +
Sbjct: 26568 ------IADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD-PCDPPGQPEV 26620
Query: 293 NALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRR 352
++ +SV + W P G + GY V + D + T I + ++ L
Sbjct: 26621 TNITRKSVSLKWSKPHYDG-GAKITGYIVERRELPDGRWLKCNYTN-IQETYFEVTELTE 26678
Query: 353 YTNYSVTVCAFTAAGD----GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
Y V A AA P+ + + P D+K R+ I+V
Sbjct: 26679 DQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKF----RDVIVVKAGEVL 26734
Query: 409 SPNGVLVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPP---RATHQFWVSASTR 464
N + G L +S +DG E R ST +H R T Q+ ++
Sbjct: 26735 KINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNV 26794
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G VL PA N +T E SLS + A
Sbjct: 26795 AGTRSVAVNCKVLDKPGPPAGPLEI--NGLTA--EKCSLSWGRPQEDGGADIDYYIVEKR 26850
Query: 525 ESTLRKNVSSDGTLTIS---MTQSADSGNYTCSVENI--HGRDEVTYTVEVK------VP 573
E++ +G L ++ +T+ Y V + +G E +V +K VP
Sbjct: 26851 ETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVP 26910
Query: 574 PQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
P L + +S+ L WS + DGGS I GY+I + ++ W + + V
Sbjct: 26911 SPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVK 26970
Query: 632 PN-LWCGTRYQLYITAFNRIGTGLPCD---IVHAYTKGTVPVKPKHSQMITLNTTTVTV- 686
L G Y+ + A N G LP + ++ A +P P +++ TT+T+
Sbjct: 26971 STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIA 27030
Query: 687 WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHN 746
W+ DGG I + +EY++ W+ S++ TE +++SGLT A Y R+ + N
Sbjct: 27031 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE--YTISGLTTGAEYVFRVKSVN 27088
Query: 747 NAG 749
G
Sbjct: 27089 KVG 27091
Score = 127 bits (306), Expect = 2e-28
Identities = 157/709 (22%), Positives = 287/709 (40%), Gaps = 69/709 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P ++V D T+ + W++P + G II YI++ +A W + V
Sbjct: 29181 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK--- 29237
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +V +LQ Y R+ A N G+ + + + + P D+ K T ++
Sbjct: 29238 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ-THVV 29296
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
G + ++ +Q + + V S P ++ ++R + S T+
Sbjct: 29297 RA----------GASIRLFIAYQGRPTPTAVW--SKPD-SNLSLRADIHTTDSFSTLTVE 29343
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
++ A + N+ + D P PPG + ++ S + W+ P
Sbjct: 29344 NCNRNDAGKYTLTVENN---SGSKSITFTVKVLDTPG-PPGPITFKDVTRGSATLMWDAP 29399
Query: 308 PMRGRNGILQGYRVTYAPVT--DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
+ G + Y V + W + T+QI ++ G+ Y + V+
Sbjct: 29400 LLDG-GARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY--FRVSAVNEYG 29456
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVI 424
G+ TE+ P+ P + +S++ +++WL P G + GY L M
Sbjct: 29457 VGEPYEMPEPIVATEQ--PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM--- 29511
Query: 425 EDGREEGTHKRMLSPST--LSHETSRSPPRATHQFWVSASTRLGEGEA----TRVVTVLP 478
R++G+ + + T L+ R + ++F V A G E + V+ P
Sbjct: 29512 ---RQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEP 29568
Query: 479 SDSVPARITSFSRNIVT-----PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
A +T + ++T P+ ++ +S G PAP TW + + L+ T R +++
Sbjct: 29569 QIEPTADLTGITNQLITCKAGSPFTIDVPIS----GRPAPKVTWKLEEMRLKETDRVSIT 29624
Query: 534 SDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADS 588
+ TLT+ + DSG Y ++EN G + TV V P P + V A+S
Sbjct: 29625 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAES 29684
Query: 589 LHLQWSDQGD-GGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYIT 645
L W + D GG+ I Y++ KRE G W+ + ++ + +L Y ++
Sbjct: 29685 CVLSWGEPKDGGGTEITNYIVE-KRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVS 29743
Query: 646 AFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ NR G P + H + + P +P+ ++ N ++ W + + DGG I+
Sbjct: 29744 SENRFGVSKPLESAPIIAEHPFVPPSAPTRPE-VYHVSANAMSIR-WEEPYHDGGSKIIG 29801
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +E +E + W + N V E + V+GL YQ R A N AG
Sbjct: 29802 YWVEKKERNTILW-VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 29849
Score = 126 bits (305), Expect = 3e-28
Identities = 160/712 (22%), Positives = 284/712 (39%), Gaps = 63/712 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P PK ++ D ++ ++W P G SP+ Y+V+ +E T KV+ +
Sbjct: 14415 PSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRK---TWTKVMDFVTDL 14471
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+V +L Y ++ A N+ G EP+ +PV ++T VP PP++V+ +++
Sbjct: 14472 EFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPD-PPENVKWRDRTANS 14530
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP+ D I GY ++ P G+ V G A ++
Sbjct: 14531 IFLTWDPPKND-GGSRIKGY-------------IVERCPRGSDKWVAC--GEPVAETKME 14574
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL++ YA V+A N + D P L L+ +V+ +
Sbjct: 14575 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 14634
Query: 306 ---PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVT-KQISGLHT-TLSGLRRYTNYSVTV 360
P + G+ ++T+ + +T + + T T+ +R + +
Sbjct: 14635 IELPATVTGK----PEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII 14690
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
A G RA V D P PA + L++W PP G + T Y
Sbjct: 14691 EAVNVCG---RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI--TNY 14745
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLP 478
+ E HK + + + ++ P + F V+A G GE + +T
Sbjct: 14746 VVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKY 14805
Query: 479 SDSVPARITSFSRNIVTPWKENISLS-CNKVGVP-APATTWTMNGVGLEST----LRKNV 532
P T + +T K+ ++L+ C +P T + + + ++ K
Sbjct: 14806 QFDPPGPPTRLEPSDIT--KDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMP 14863
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVV-DSY 585
D T + + + EN+ G + + + E + PP PP V D
Sbjct: 14864 VKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVG 14923
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLY 643
S+ L W+ + DGG+ I YVI + D W + T++H+LP L G Y
Sbjct: 14924 KTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFR 14983
Query: 644 ITAFNRIG---TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
+ A N+ G P D V K P P+ ++I + T + W DGG I
Sbjct: 14984 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPIT 15043
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+++E R++ + W+ V +V+ T+ +V+ LT + Y R+ A N G +
Sbjct: 15044 NYIVEKRDVRRKGWQTVDTTVKDTK--CTVTPLTEGSLYVFRVAAENAIGQS 15093
Score = 126 bits (304), Expect = 4e-28
Identities = 125/486 (25%), Positives = 204/486 (41%), Gaps = 30/486 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYGNEDAVTK 338
D P PP + +S S V+WEPP + G + I+ Y V A W VT
Sbjct: 20712 DTPG-PPVNVTVKEISKDSAYVTWEPPIIDGGSPIIN-YVVQKRDAERKSW----STVTT 20765
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ S ++ L +Y V A G G P D+K S++
Sbjct: 20766 ECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKS 20825
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
+ W P S G ++GY V++ EE +R++ +L + + F
Sbjct: 20826 SCSIGWKKPHSDGGSRIIGY-----VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTF 20880
Query: 458 WVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKENIS--LSCNKVGVPAPA 514
VSA GEG + + V D V P ++ KEN + L G PAP+
Sbjct: 20881 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 20940
Query: 515 TTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
+W L + R +V S TL + Q +D+G YT +++N+ G E T +++V
Sbjct: 20941 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 21000
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE--HGDWEELQVEAGT 626
P P + + A+++ L+W+ + DGGS I Y++ KR+ + W
Sbjct: 21001 GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSVNNKWVTCASAVQK 21059
Query: 627 SEHVLPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ + L G Y ++A N+ +G GL + + A VP P ++ + +V
Sbjct: 21060 TTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSV 21119
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
++ W D GG I + +E++E + W+ +N R F V+GLT Y+ R+
Sbjct: 21120 SLTWTDPKKTGGSPITGYHLEFKERNSLLWKR-ANKTPIRMRDFKVTGLTEGLEYEFRVM 21178
Query: 744 AHNNAG 749
A N AG
Sbjct: 21179 AINLAG 21184
Score = 126 bits (303), Expect = 6e-28
Identities = 155/614 (25%), Positives = 250/614 (40%), Gaps = 50/614 (8%)
Query: 157 SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
S PV V + P P V+V +S + +TW PP +D G+ + +YV +
Sbjct: 24635 SFPVNVKVLDR-PGPPEGPVQVTGVTSEKCSLTWSPPLQD--GGSDISHYV----VEKRE 24687
Query: 217 TVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXX 276
T +A +TV E + T L ++ + V Y
Sbjct: 24688 TSRLA-------WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMK 24740
Query: 277 XXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNED 334
+P PP +L+ ++ S+ V W P G + I+ GY V + W
Sbjct: 24741 NPFV-LPG-PPKSLEVTNIAKDSMTVCWNRPDSDGGSEII-GYIVEKRDRSGIRWI---K 24794
Query: 335 AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA-APVYCHTEEDV--PSAPADIK 391
++I+ L ++GL Y V A AAG G + A VY + V P P +
Sbjct: 24795 CNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAH 24854
Query: 392 AAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST----LSHET 446
+++N I ++W P G ++GY V+E + + ++++P T E
Sbjct: 24855 IVDTTKNSITLAWGKPIYDGGSEILGY-----VVEICKADEEEWQIVTPQTGLRVTRFEI 24909
Query: 447 SRSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENI 501
S+ ++ V A ++G GEAT V TV P D + A + + IV +
Sbjct: 24910 SKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSA 24969
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHG 560
+ G P P TW+ ++ + T L+I D+G Y +EN G
Sbjct: 24970 RIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG 25029
Query: 561 RDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGD 616
TV+V P PP LAV + DS L W DGG+ + YVI+ KRE
Sbjct: 25030 SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID-KRESTRKA 25088
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
+ + + + + NL G Y + A N G G+P + V A P P +
Sbjct: 25089 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 25148
Query: 677 ITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
++ T+ + +W DGG +L +V+E + +W +V+ S + V V+GL+
Sbjct: 25149 TDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV--VTGLSSG 25205
Query: 736 AHYQLRITAHNNAG 749
YQ R+ A+N G
Sbjct: 25206 QEYQFRVKAYNEKG 25219
Score = 125 bits (301), Expect = 1e-27
Identities = 146/644 (22%), Positives = 248/644 (38%), Gaps = 41/644 (6%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+VTS S++ + N G + P+ + + GPP +R++ S
Sbjct: 26375 TVTSLSIKEASKEDVGTYELCVSNSAGSI--TVPITIIVLDR--PGPPGPIRIDEVSCDS 26430
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W PP+ D I Y V +E S + +++ AR+
Sbjct: 26431 ITISWNPPEYD-GGCQISNYIVEKKETTSTTWHIVSQA---------------VARTSIK 26474
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSW 304
+ L + Y V A N P PPG + + ++ V+W
Sbjct: 26475 IVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 26534
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
+ P G + ++ GY + Y + ++ A I+ +SGL Y V A
Sbjct: 26535 QVPVNDGGSRVI-GYHLEYKERSSILWSK-ANKILIADTQMKVSGLDEGLMYEYRVYAEN 26592
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSV 423
AG G + D P + +R + + W P G + GY +
Sbjct: 26593 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 26652
Query: 424 IEDGREEGTHKRMLSPSTLS-HETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+ DGR + + + E + F +A+ + E + ++ D
Sbjct: 26653 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 26712
Query: 483 PARI---TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDG-- 536
P R+ F IV E + ++ + G P P +W +G+ +E R +S+D
Sbjct: 26713 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 26772
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
LT+ D+G Y +++N+ G V +V P PP L + A+ L W
Sbjct: 26773 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWG 26832
Query: 595 -DQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
Q DGG+ I Y++ KRE H W + E + + L G Y +T N+ G
Sbjct: 26833 RPQEDGGADIDYYIVE-KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYG 26891
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
G P + + A TVP P ++ ++ ++T+ W DGG I ++IE RE
Sbjct: 26892 VGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREK 26951
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+ +W V+ RV S +GL Y+ R+ A N AG +L
Sbjct: 26952 NSLRWVRVNKKPVYDLRVKS-TGLREGCEYEYRVYAENAAGLSL 26994
Score = 124 bits (299), Expect = 2e-27
Identities = 157/633 (24%), Positives = 243/633 (38%), Gaps = 56/633 (8%)
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
H + N G++ + V V P+GP V+++ ++ + ++W PP+ D G+
Sbjct: 23144 HYVVKLTNSAGEAIETLNVIVLDKPGPPTGP---VKMDEVTADSITLSWGPPKYD--GGS 23198
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ Y+ + S +T I S A AR+ L+ Y + A
Sbjct: 23199 SINNYIVEKRDTSTTTWQIVS--------------ATVARTTIKACRLKTGCEYQFRIAA 23244
Query: 262 YN--SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
N + VP PPG S S+ V W P G + ++ GY
Sbjct: 23245 ENRYGKSTYLNSEPTVAQYPFKVPG-PPGTPVVTLSSRDSMEVQWNEPISDGGSRVI-GY 23302
Query: 320 RVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
+ W Q TT GL Y V A G G + C
Sbjct: 23303 HLERKERNSILWVKLNKTPIPQTK-FKTT--GLEEGVEYEFRVSAENIVGIGKPSKVSEC 23359
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRM 436
+ D P +A + +RN + + W P+ G + GY + + +GR K
Sbjct: 23360 YVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGR---WMKAS 23416
Query: 437 LSPSTLSH-ETSRSPPRATHQFWVSASTRLG----EGEATRVVTVLPSDSV-PARIT--- 487
+ +H E + ++F V A G E+T +T D V P RI+
Sbjct: 23417 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITA--RDEVDPPRISMDP 23474
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA 546
+ IV E+ + + G P P W L +T R + S+D ++S+ +
Sbjct: 23475 KYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAV 23534
Query: 547 --DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS--YADSLHLQWSDQ-GDGGS 601
DSGNY +N+ G VT V+V P PP VV S A+ L W DGGS
Sbjct: 23535 RVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGS 23594
Query: 602 PILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
I+ Y++ +RE W + T + L G Y I A N+ G G P +
Sbjct: 23595 DIINYIVE-RRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE 23653
Query: 660 HAYTKG--TVPVKPKHSQMITL-NTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
K VP PK ++ T+ + + VW DGG IL +V+E R+ +W
Sbjct: 23654 PVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRC 23713
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ R+ V+GL Y+ R++A N AG
Sbjct: 23714 HKRLIGELRL-RVTGLIENHDYEFRVSAENAAG 23745
Score = 121 bits (291), Expect = 2e-26
Identities = 121/483 (25%), Positives = 198/483 (40%), Gaps = 28/483 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
PG + + ++ S+ ++W P G + I Q Y + + + IS
Sbjct: 29082 PGIPEPSNITGNSITLTWARPESDGGSEIQQ-YILERREKKSTRWVKVISKRPISETRFK 29140
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAAVSSRNKILVS 403
++GL Y V A AAG G + + C + P P +K +S+ + +
Sbjct: 29141 VTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLE 29200
Query: 404 WLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT-HQFWVSA 461
W P G+ ++GY + M + G HK + T ++F VSA
Sbjct: 29201 WSKPVFDGGMEIIGYIIEMCKADLG---DWHKVNAEACVKTRYTVTDLQAGEEYKFRVSA 29257
Query: 462 STRLGEGEATRVV-TVLPSDSVPARI----TSFSRNIVTPWKENISLSCNKVGVPAPATT 516
G+G++ V T+ D + A +F + V +I L G P P
Sbjct: 29258 INGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAV 29317
Query: 517 WTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W+ L +LR ++ S TLT+ D+G YT +VEN G +T+TV+V
Sbjct: 29318 WSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDT 29375
Query: 574 PQPP-ILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKRE--HGDWEELQVEAGTSEH 629
P PP + D S L W + DGG+ I YV+ KRE W+ + +
Sbjct: 29376 PGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVE-KREASRRSWQVISEKCTRQIF 29434
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI-TLNTTTVTVWL 688
+ +L G Y ++A N G G P ++ P P+ ++ T ++ V WL
Sbjct: 29435 KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWL 29494
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG I +++E R+ W ++ Q T F+V L Y+ R+ A N+A
Sbjct: 29495 KPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLT---FTVERLVEKTEYEFRVKAKNDA 29551
Query: 749 GHA 751
G++
Sbjct: 29552 GYS 29554
Score = 120 bits (288), Expect = 4e-26
Identities = 126/485 (25%), Positives = 194/485 (40%), Gaps = 31/485 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG + ++ S+ V W P G + I GY + G + + I
Sbjct: 27995 PPGIPEVTKITKNSMTVVWSRPIADGGSDI-SGYFLEKRDKKS-LGWFKVLKETIRDTRQ 28052
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNKILV 402
++GL ++Y VCA AAG G + P + D P PA I+ A S+++ I +
Sbjct: 28053 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 28112
Query: 403 SWLPPSSPNGVLVGYTLYMSVIEDGREE--GTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P G V T Y+ I G EE T T + S P + F VS
Sbjct: 28113 GWSKPVYDGGSAV--TGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 28170
Query: 461 ASTRLGEG------EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G+G E + +L + + + + +++ E++ + G P P
Sbjct: 28171 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDV-ALRTSVIAKAGEDVQVLIPFKGRPPPT 28229
Query: 515 TTWTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + L S R +N S LTI D+G Y ++EN G + + TV VK
Sbjct: 28230 VTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVK 28288
Query: 572 VPPQPPI---LAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P L V ++ L W DGGSPI+ YVI KR+ W + +
Sbjct: 28289 VLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE-KRDATKRTWSVVSHKCS 28347
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH-SQMITLNTTTV 684
++ L +L T + + A N IG G PC+ VP + S + T+ +
Sbjct: 28348 STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI 28407
Query: 685 TVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
W DGG I +V+E + + W S++ + VS L + + R+ A
Sbjct: 28408 LSWTKPDFDGGSVITEYVVERKGKGEQTW---SHAGISKTCEIEVSQLKEQSVLEFRVFA 28464
Query: 745 HNNAG 749
N G
Sbjct: 28465 KNEKG 28469
Score = 118 bits (285), Expect = 9e-26
Identities = 164/709 (23%), Positives = 270/709 (38%), Gaps = 57/709 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N +VID ++ +SW++P Y G I YIV+ + W TP I +
Sbjct: 23765 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI---N 23821
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T+ V+ L Y+ RI A N+ G E + EE P D+ +E + +
Sbjct: 23822 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINI 23881
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
G L +V + T + G + ++ + L
Sbjct: 23882 RA-----------GGSLRLFV---PIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 23927
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ ++ + + NS + D PS PP L+ ++ SV ++WEP
Sbjct: 23928 DNVNRYDSGKYTLTLENS---SGTKSAFVTVRVLDTPS-PPVNLKVTEITKDSVSITWEP 23983
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + G + I + Y V T + AV + L+ +Y V A
Sbjct: 23984 PLLDGGSKI-KNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 24040
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIE 425
G G+ A +VP P I +RN + +SW P G ++ Y + M
Sbjct: 24041 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 24100
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE----ATRVVT---VLP 478
+ + + +++ T + F V A G + A +V V+
Sbjct: 24101 SEKWSECARVKSLQAVITNLTQGEE----YLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE 24156
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD--- 535
D PA +S+S + K + +S G P P TWT +G+ L+ T R NV+
Sbjct: 24157 PDVKPA-FSSYSVQVGQDLKIEVPIS----GRPKPTITWTKDGLPLKQTTRINVTDSLDL 24211
Query: 536 GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADSLHLQW 593
TL+I T D G Y +V N+ G+ + + P PP V D A+S+ L W
Sbjct: 24212 TTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSW 24271
Query: 594 SDQ-GDGGSPILGYVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ GG I Y++ KR+ W+ + + + L GT YQ I A NR
Sbjct: 24272 NPPLYTGGCQITNYIVQ-KRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRY 24330
Query: 651 GT--GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYRE 707
G L D + A P P ++ ++ + W + +GG ++ + +E +E
Sbjct: 24331 GQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKE 24390
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYN 756
+ W V+ ++ + F L Y+ R+ A N G A N
Sbjct: 24391 RNSILWTKVNKTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKN 24438
Score = 118 bits (283), Expect = 2e-25
Identities = 156/650 (24%), Positives = 247/650 (38%), Gaps = 60/650 (9%)
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+T+ S++ I N +GQ S +++ T ++ P P V+ + S+ +
Sbjct: 24211 LTTLSIKETHKDDGGQYGITVANVVGQKTAS--IEIVTLDK-PDPPKGPVKFDDVSAESI 24267
Query: 187 IVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++W PP L+ G I Y V Q+ ++ +TV V A AR+
Sbjct: 24268 TLSWNPP---LYTGGCQITNYIV--QKRDTTTTVW-------------DVVSATVARTTL 24309
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL-PPGALQCNALSSQSVRVS 303
++ L+ Y + A N PPG A+S S+ +
Sbjct: 24310 KVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQ 24369
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G + ++ GY + + V K I +H T L Y V
Sbjct: 24370 WHEPVNNGGSPVI-GYHLERKERNSILWTK--VNKTI--IHDTQFKAQNLEEGIEYEFRV 24424
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTL 419
A G G + C+ D P + + RN+I + W P G ++ GY +
Sbjct: 24425 YAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIV 24484
Query: 420 YMSVIEDGR-EEGTHKRMLSPS-TLSHETSRSPPRATHQFWVSASTRLG----EGEATRV 473
+ DGR + + ++ T+S T ++F V A G ++T
Sbjct: 24485 EKRDLPDGRWMKASFTNVIETQFTVSGLTEDQ----RYEFRVIAKNAAGAISKPSDSTGP 24540
Query: 474 VTVLPSDSVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR- 529
+T +P RI+ F IV E L + G P P W +E + R
Sbjct: 24541 ITAKDEVELP-RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARC 24599
Query: 530 --KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSY 585
KN L + D G Y N+ G V+V P PP + V
Sbjct: 24600 EIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVT 24659
Query: 586 ADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQL 642
++ L WS DGGS I YV+ KRE W + E T+ + L G Y
Sbjct: 24660 SEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVF 24718
Query: 643 YITAFNRIGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGIL 699
I A N+ G G P + K +P PK ++ + ++TV W DGG I+
Sbjct: 24719 RIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEII 24778
Query: 700 YFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++E R+ S +W + N + T+ V+GLT Y+ R++A N AG
Sbjct: 24779 GYIVEKRDRSGIRW-IKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAG 24827
Score = 118 bits (283), Expect = 2e-25
Identities = 160/702 (22%), Positives = 267/702 (38%), Gaps = 57/702 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N ++D +I ++W +P Y G S I+ Y+V+ +A E W TPQ +
Sbjct: 24847 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL---R 24903
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
VT + L Y +R+ A N++G E + E+ P D+ E + +
Sbjct: 24904 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG--I 24961
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+V G ++ F+ T I +T + G ++ ++
Sbjct: 24962 VVR---------AGGSARIHIPFK---GRPTPEITWSREEGEFTDKVQIEKGVNYTQLSI 25009
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ A +++ NS + D P PP L + S + WEP
Sbjct: 25010 DNCDRNDAGKYILKLENS---SGSKSAFVTVKVLDTPG-PPQNLAVKEVRKDSAFLVWEP 25065
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P + G ++ Y + T Y N V+ + S + L Y V A
Sbjct: 25066 PIIDG-GAKVKNYVIDKRESTRKAYAN---VSSKCSKTSFKVENLTEGAIYYFRVMAENE 25121
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVI 424
G GV V + PS P + S+ + W P G V GY + M
Sbjct: 25122 FGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM--- 25178
Query: 425 EDGREEGTHK-RMLSPSTLSHETSRSPPRAT-HQFWVSASTRLGEGEATRV-VTVLPSDS 481
+ +GT K +++ S + + +QF V A G+ + + V V+ D
Sbjct: 25179 ---QPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDL 25235
Query: 482 V--PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P+ F+ + E++ + +G P P +W +G L+ T R NV T T
Sbjct: 25236 TIQPSLKLPFNTYSIQAG-EDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 25294
Query: 540 ISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQWS 594
+ + D G YT + N G +V V P PP+ + + AD + + W
Sbjct: 25295 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWE 25354
Query: 595 DQG-DGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
GG I Y++ KR+ W + + + L GT YQ I A NR G
Sbjct: 25355 PPAYTGGCQISNYIVE-KRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYG 25413
Query: 652 TGLPCD--IVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
P D V P P + +++ + V W + DGG I+ + +E +E
Sbjct: 25414 KSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEK 25473
Query: 709 SQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ W +L +Q T+ F +GL Y+ +++A N G
Sbjct: 25474 NSILWVKLNKTPIQDTK--FKTTGLDEGLEYEFKVSAENIVG 25513
Score = 117 bits (282), Expect = 2e-25
Identities = 150/625 (24%), Positives = 245/625 (39%), Gaps = 46/625 (7%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
+ A N +G+ +QV ++P P ++ + SS + +W+PP+ D I
Sbjct: 22065 LTARNIVGEVGDVITIQV---HDIPGPPTGPIKFDEVSSDFVTFSWDPPEND-GGVPISN 22120
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y V ++ +S + V +A+ +RT T ++ +GL+ + V Q
Sbjct: 22121 YVVEMRQTDSTTWVELATT------VIRT-----TYKATRLTTGLEYQ--FRVKAQNRYG 22167
Query: 265 RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA 324
VP PPG Q A++ S+ +SW P G + IL GY V
Sbjct: 22168 VGPGITSACIVANYPFKVPG-PPGTPQVTAVTKDSMTISWHEPLSDGGSPIL-GYHVERK 22225
Query: 325 PVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
W A+ + G SGL Y V A AG + P D
Sbjct: 22226 ERNGILWQTVSKAL---VPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALD 22282
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPST 441
P +R+ + + W P G + Y + + +GR + + +
Sbjct: 22283 PIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENE 22342
Query: 442 LSHETSRSPPRATHQFWVSASTRLGE----GEATRVVTVLPSDSVPA-RI-TSFSRNIVT 495
+ S A ++F V A G E + +T P ++ F ++
Sbjct: 22343 FT--VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 22400
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGTLTISMTQSA--DSGNYT 552
E L + G P P W+ +G LE T + + +D + + S DSG YT
Sbjct: 22401 KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 22460
Query: 553 CSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYADSLHLQW-SDQGDGGSPILGYVIN 609
+ N G + + V+V P PP LAV + ++ L W DGG+ I Y++
Sbjct: 22461 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQ 22520
Query: 610 YKREHG--DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKG 665
KRE W + E ++ + L G Y + A N+ G G P + V A
Sbjct: 22521 -KRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPY 22579
Query: 666 TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE 724
P PK+ ++ T+ ++ V W DGG I+ +++E R+ + +W + N T+
Sbjct: 22580 GPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRW-IKCNKKTLTD 22638
Query: 725 RVFSVSGLTPAAHYQLRITAHNNAG 749
+ VSGLT Y+ RI A N AG
Sbjct: 22639 LRYKVSGLTEGHEYEFRIMAENAAG 22663
Score = 117 bits (281), Expect = 3e-25
Identities = 141/615 (22%), Positives = 239/615 (38%), Gaps = 52/615 (8%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ V T PS P +R + + +I++W+ P+ D G I Y + +E + +
Sbjct: 28575 PITVITLGP-PSKPKGPIRFDEIKADSVILSWDVPE-DNGGGEITCYSIEKRETSQTNWK 28632
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX 278
++ S AR+ + L K A Y V+A N
Sbjct: 28633 MVCSS---------------VARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVA 28677
Query: 279 MED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV 336
+P PPG ++S + ++W+ P G + + G+ V +
Sbjct: 28678 KHQFRIPG-PPGKPVIYNVTSDGMSLTWDAPVYDGGSEVT-GFHVEKKERNSILWQK-VN 28734
Query: 337 TKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAA 393
T ISG +GL +Y V A +AG + P + D P P I
Sbjct: 28735 TSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDV- 28793
Query: 394 VSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPR 452
+R I + W PP G +VGY++ G E S + + P
Sbjct: 28794 --TRETITLKWNPPLRDGGSKIVGYSIEK---RQGNERWVRCNFTDVSECQYTVTGLSPG 28848
Query: 453 ATHQFWVSASTRLGE---GEATRVVTVLPSDSVPARIT---SFSRNIVTPWKENISLSCN 506
++F + A +G + + + ++VP + + ++ E++ +
Sbjct: 28849 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 28908
Query: 507 KVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTISMTQSADS--GNYTCSVENIHGRDE 563
G P P TW +GV +E + ++ G+ ++ + + G YT +N G +
Sbjct: 28909 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28968
Query: 564 VTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHGD--WE 618
V+V+ P + + + + + L W + DG +PI Y+I KRE W
Sbjct: 28969 AEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE-KRETSRLAWA 29027
Query: 619 ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI--VHAYTKGTVPVKP--KHS 674
++ + + L G YQ ++A N+ G G P D V A + TVP P
Sbjct: 29028 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEP 29087
Query: 675 QMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
IT N+ T+T W DGG I +++E RE +W V + +E F V+GLT
Sbjct: 29088 SNITGNSITLT-WARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTE 29146
Query: 735 AAHYQLRITAHNNAG 749
Y+ + A N AG
Sbjct: 29147 GNEYEFHVMAENAAG 29161
Score = 114 bits (275), Expect = 1e-24
Identities = 118/490 (24%), Positives = 191/490 (38%), Gaps = 33/490 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQ 339
VPS P A + ++ + V+W+ P G + I+ GY + W D + +
Sbjct: 20018 VPSEPKNA-RVTKVNKDCIFVAWDRPDSDGGSPII-GYLIERKERNSLLWVKANDTLVRS 20075
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
+GL YS + A AG + P T P + +++
Sbjct: 20076 TE---YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST 20132
Query: 400 ILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+ + W P G ++GY + + + + + + +A +QF
Sbjct: 20133 VSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFR 20192
Query: 459 VSASTRLG---EGEATRVVTVLPSDSVPARI---TSFSRNIVTPWKENISLSCNKVGVPA 512
A T + E + VT+L +++VP RI + + N+ L G P
Sbjct: 20193 AIARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPM 20251
Query: 513 PATTWTMNGV------GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
P +W +G G++ +++N+ TL + DSG+YT + EN G T
Sbjct: 20252 PTVSWKKDGTLLKPAEGIKMAMQRNLC---TLELFSVNRKDSGDYTITAENSSGSKSATI 20308
Query: 567 TVEVKVPPQPPILAVVDS-YADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQV 622
++V P PP ++ Y+D L W DGGS I Y+++ KRE +W ++
Sbjct: 20309 KLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD-KRETSRPNWAQVSA 20367
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L G YQ I A N+ G G P A K + + N T
Sbjct: 20368 TVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNIT 20427
Query: 683 T--VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+TV W DGG I +++E RE W V N ER +GL Y+
Sbjct: 20428 KDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKV-NRKPIIERTLKATGLQEGTEYE 20486
Query: 740 LRITAHNNAG 749
R+TA N AG
Sbjct: 20487 FRVTAINKAG 20496
Score = 113 bits (273), Expect = 2e-24
Identities = 122/493 (24%), Positives = 197/493 (39%), Gaps = 35/493 (7%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYG-NEDAVTKQISGL 343
P + +S + + V W PP G I GY + T W N+ A+ ++ +
Sbjct: 19326 PDPPEVTKVSKEEMTVVWNPPEYDGGKSIT-GYFLEKKEKHSTRWVPVNKSAIPERRMKV 19384
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
L Y V A G G + + PV + P P + + ++++ I
Sbjct: 19385 QNLLPD----HEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 19440
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHE---TSRSPPRATH 455
+ W P G ++GY + M I D + KR + + L + + +
Sbjct: 19441 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 19500
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSV--PARI---TSFSRNIVTPWKENISLSCNKVGV 510
+F V A ++G G + + + P I S + ++ I L G
Sbjct: 19501 EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR 19560
Query: 511 PAPATTWTMNGVGLESTLRKN----VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
PAP TW VG+++ +RK V + L I + DSG Y+ ++ N G V
Sbjct: 19561 PAPKVTWRK--VGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 19618
Query: 567 TVEVKVPPQPPI-LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKR-EHGDWEELQVE 623
V V P P L V D S H+ W+ + DGGS + Y++ + + W + E
Sbjct: 19619 NVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPE 19678
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
+ + NL G Y +TA N G G+P D+ V A + P P+ ++ +
Sbjct: 19679 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 19738
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
+ T+ WL DGG I ++ YRE QP R SV + V+GL Y+
Sbjct: 19739 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYK 19797
Query: 740 LRITAHNNAGHAL 752
R+ A N G +L
Sbjct: 19798 FRVAARNAVGVSL 19810
Score = 113 bits (271), Expect = 4e-24
Identities = 150/629 (23%), Positives = 244/629 (38%), Gaps = 58/629 (9%)
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I AEN G + ++V + P GPP V++ S +++WEPP D I
Sbjct: 20295 ITAENSSGSKSATIKLKVL---DKP-GPPASVKINKMYSDRAMLSWEPPLED-GGSEITN 20349
Query: 205 YYVGFQELNS-NSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y V +E + N + A+ P + + +EG H Y + A N
Sbjct: 20350 YIVDKRETSRPNWAQVSATVPITSCSVEKLIEG---------------HE-YQFRICAEN 20393
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSS---QSVRVSWEPPPMRGRNGILQGYR 320
P PPG +S+ + VSW+PP G + I GY
Sbjct: 20394 KYGVGDPVFTEPAIAKN--PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPIT-GYL 20450
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYC 377
+ T K I +GL+ T Y V A AG G + Y
Sbjct: 20451 LEKRE-TQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYA 20509
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTH-KR 435
+ P+ PA K ++R+ + +SW P+ G ++GY ++E R + + R
Sbjct: 20510 RDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGY-----LVEVKRADSDNWVR 20564
Query: 436 MLSPSTLSH---ETSRSPPRATHQFWVSASTRLGEGEATRVVTV-LPSDS-VPAR---IT 487
P L E + +QF V A ++G + + V P D +P
Sbjct: 20565 CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDA 20624
Query: 488 SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS---DGTLTISMTQ 544
+ ++ + L G P P TW+ V L + ++ S D L
Sbjct: 20625 DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVN 20684
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQ-GDGGSP 602
D+G Y ++EN G+ E T V+V P PP+ + V + DS ++ W DGGSP
Sbjct: 20685 KYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSP 20744
Query: 603 ILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
I+ YV+ + E W + E + + NL G Y + A N G G P + A
Sbjct: 20745 IINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 20804
Query: 662 YTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSV 720
P ++ +++ ++ ++ W DGG I+ +V+++ + +W+ V S+
Sbjct: 20805 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL 20863
Query: 721 QATERVFSVSGLTPAAHYQLRITAHNNAG 749
+S LT Y R++A N G
Sbjct: 20864 SLQ---YSAKDLTEGKEYTFRVSAENENG 20889
Score = 111 bits (268), Expect = 1e-23
Identities = 114/482 (23%), Positives = 185/482 (38%), Gaps = 20/482 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P L+ ++ SV + W+ P + G + I Y V T + T +
Sbjct: 21793 DTPG-PVLNLRPTDITKDSVTLHWDLPLIDGGSRITN-YIVEKREATR--KSYSTATTKC 21848
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
++GL Y V A G G + PS P + +++ +
Sbjct: 21849 HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTV 21908
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
++W P G + GY + G ++ TH + T Q
Sbjct: 21909 SLAWPKPKHDGGSKITGYVIEAQ--RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMA 21966
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTW 517
S +R V V +P + + ++ +NI + +G P P TW
Sbjct: 21967 VNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW 22026
Query: 518 TMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L+ T R N + T L I+ +DSG Y + NI G T++V P
Sbjct: 22027 KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP 22086
Query: 575 QPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
PP + + +D + W + DGG PI YV+ ++ + W EL + +
Sbjct: 22087 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 22146
Query: 631 LPNLWCGTRYQLYITAFNR--IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-W 687
L G YQ + A NR +G G+ + A VP P Q+ + ++T+ W
Sbjct: 22147 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 22206
Query: 688 LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNN 747
+ DGG IL + +E +E + W+ VS ++ +F SGLT Y+ R+ A N
Sbjct: 22207 HEPLSDGGSPILGYHVERKERNGILWQTVSKAL-VPGNIFKSSGLTDGIAYEFRVIAENM 22265
Query: 748 AG 749
AG
Sbjct: 22266 AG 22267
Score = 111 bits (266), Expect = 2e-23
Identities = 155/701 (22%), Positives = 253/701 (36%), Gaps = 48/701 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ-YKEAPESWPSTPQKVIVPGSV 127
P P N ++ D+ T + WT+P + G SPI+ Y+V+ K W + ++
Sbjct: 18731 PGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELI--RQ 18788
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L Y RI A N +G+ EP + + +++ PP+ VE + +
Sbjct: 18789 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILH-PPE---VELDVTCRDV 18844
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+T Q + G VL+ V ++ + +
Sbjct: 18845 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK------RVDLIQDLPRVELQIKEA 18898
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
H Y ++ A NS + D P P L+ ++ ++ +SWE P
Sbjct: 18899 VRADHGKY--IISAKNS---SGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENP 18952
Query: 308 PMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
G + I + V Y W VTK++ + L Y VCA
Sbjct: 18953 LDNGGSEITN-FIVEYRKPNQKGWSIVASDVTKRL-----IKANLLANNEYYFRVCAENK 19006
Query: 366 AGDGVRA---APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL-VGYTLYM 421
G G P+ D P P ++ A + + + W P G + Y +
Sbjct: 19007 VGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVER 19066
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
+ E HK + + + R ++F V GE + + V+ +
Sbjct: 19067 RLKGSDDWERVHKGSIKET--HYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKED 19124
Query: 482 VPARITSFSRNIVTPWK--ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---- 535
+ + + V K + I L G P P WT + + T V D
Sbjct: 19125 LQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 19184
Query: 536 -GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQW 593
+++ + +D G Y + N G TV V P P L +VD +D + W
Sbjct: 19185 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCW 19244
Query: 594 SD-QGDGGSPILGYVINY-KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ DGG I Y++ + + W T + L G Y + A N+IG
Sbjct: 19245 DPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG 19304
Query: 652 TGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREM 708
TG P + V A TK P +P ++ ++ +T VW DGG I + +E +E
Sbjct: 19305 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEK 19364
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ S ER V L P YQ R+ A N G
Sbjct: 19365 HSTRWVPVNKSA-IPERRMKVQNLLPDHEYQFRVKAENEIG 19404
Score = 110 bits (265), Expect = 2e-23
Identities = 119/481 (24%), Positives = 182/481 (37%), Gaps = 21/481 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D PS P L + SV +SWEPP + G + Y V T +T
Sbjct: 26124 DSPSAPVN-LTIREVKKDSVTLSWEPPLIDG-GAKITNYIVEKRETTR--KAYATITNNC 26179
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
+ + L+ +Y V A G G+ A + P P + +RN
Sbjct: 26180 TKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTA 26239
Query: 401 LVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
+ W P S G + GY + M G E+ + + TL S + F V
Sbjct: 26240 TIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVK--TLEATISGLTAGEEYVFRV 26295
Query: 460 SASTRLGEGEATRV-VTVLPSD-SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+A G + ++ V V+ D + + +E + + G P W
Sbjct: 26296 AAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNW 26355
Query: 518 TMNGVGLESTLRKNVSSDGTLT---ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+G L+ T R NVSS T+T I D G Y V N G V T+ V P
Sbjct: 26356 RKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRP 26415
Query: 575 QPPILAVVDSYA-DSLHLQWS-DQGDGGSPILGYVINYKREHG-DWEELQVEAGTSEHVL 631
PP +D + DS+ + W+ + DGG I Y++ K W + + +
Sbjct: 26416 GPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKI 26475
Query: 632 PNLWCGTRYQLYITAFNRIGTG--LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WL 688
L G+ YQ + A NR G V A + P P +++ +T+ V W
Sbjct: 26476 VRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQ 26535
Query: 689 DSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNA 748
DGG ++ + +EY+E S W +N + + VSGL Y+ R+ A N A
Sbjct: 26536 VPVNDGGSRVIGYHLEYKERSSILWS-KANKILIADTQMKVSGLDEGLMYEYRVYAENIA 26594
Query: 749 G 749
G
Sbjct: 26595 G 26595
Score = 109 bits (263), Expect = 4e-23
Identities = 124/473 (26%), Positives = 189/473 (39%), Gaps = 24/473 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI-SGLHTTLSGLRRY 353
++S S+ V W P G + IL GY + V + + V K + + L + GL
Sbjct: 15841 VTSNSMLVKWNEPKDNG-SPIL-GYWLEKREVNSTHWSR--VNKSLLNALKANVDGLLEG 15896
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRNKILVSWLPPS-SP 410
Y VCA AAG G + P T D P P + +S I + W PP+ +
Sbjct: 15897 LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNG 15956
Query: 411 NGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE- 469
G +VGY + ++ ++M+ + + R A ++ VSA GEG
Sbjct: 15957 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE--GADYKLRVSAVNAAGEGPP 16014
Query: 470 -ATRVVTVLPSDSVPA--RITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
T+ VTV PA S I + + + G P P WT L+
Sbjct: 16015 GETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK 16074
Query: 527 --TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVD 583
+ NV + L I D G Y + N G VEV P P + L V
Sbjct: 16075 DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVV 16134
Query: 584 SYADSLHLQWSD-QGDGGSPILGYVINYK-REHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
+ L WSD + DGGS I G++I K + W + +E S+ + L G Y+
Sbjct: 16135 TNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ-PIETERSKCDITGLLEGQEYK 16193
Query: 642 LYITAFNRIGTGLPCDI--VHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
+ A N+ G G P +I + A P P+ +T+T+ W + +GG I
Sbjct: 16194 FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPI 16253
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
++IE R +P + V+ + T F V L Y+ R+ A N G +
Sbjct: 16254 QGYIIEKRRHDKPDFERVNKRLCPTTS-FLVENLDEHQMYEFRVKAVNEIGES 16305
Score = 109 bits (263), Expect = 4e-23
Identities = 120/487 (24%), Positives = 189/487 (38%), Gaps = 28/487 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + +A++ S+ V+W P G I +GY + + K ++
Sbjct: 25828 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEI-EGY-ILEKRDKEGVRWTKCNKKTLTD 25885
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRNK 399
L ++GL +Y V A AAG G + P + D P P++ K +SR+
Sbjct: 25886 LRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSS 25945
Query: 400 ILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHE---TSRSPPRATH 455
+ ++W P G V GY + V E +E T P+ L + ++ +
Sbjct: 25946 VSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWT--TCTPPTGLQGKQFTVTKLKENTEY 26001
Query: 456 QFWVSASTRLGEGE-ATRVVTVLPSDSV-PARI---TSFSRNIVTPWKENISLSCNKVGV 510
F + A G GE AT +V+ + + P I + +V + L G
Sbjct: 26002 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGR 26061
Query: 511 PAPATTWTM-NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P P W G+ + + SS L I DSG Y ++EN G V
Sbjct: 26062 PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVR 26121
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P P+ L + + DS+ L W DGG+ I Y++ KRE + +
Sbjct: 26122 VLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYATITNNCT 26180
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ + NL G Y + A N G GLP + P+ P ++ + T T
Sbjct: 26181 KTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTAT 26240
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG I +V+E + +W S Q ++SGLT Y R+ A
Sbjct: 26241 IKWEKPESDGGSKITGYVVEMQTKGSEKW---STCTQVKTLEATISGLTAGEEYVFRVAA 26297
Query: 745 HNNAGHA 751
N G +
Sbjct: 26298 VNEKGRS 26304
Score = 109 bits (261), Expect = 7e-23
Identities = 124/489 (25%), Positives = 186/489 (38%), Gaps = 37/489 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQISG 342
PPG ++S + V W P G I+ GY + W N+ + Q +
Sbjct: 25434 PPGTPFVTSISKDQMLVQWHEPVNDGGTKII-GYHLEQKEKNSILWVKLNKTPI--QDTK 25490
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT GL Y V A G G + C D P +A V +RN + +
Sbjct: 25491 FKTT--GLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTL 25548
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGR-EEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P+ G + GY + + DGR + + +L S ++F V
Sbjct: 25549 KWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE---FTVSGLVEDQRYEFRVI 25605
Query: 461 ASTRLGE----GEATRVVTVLPSDSVP--ARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
A G +++ +T P + + IV E L + G P P
Sbjct: 25606 ARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPD 25665
Query: 515 TTWTMNGVGLESTLR----KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
W+ +G LE T K+ TL + D G Y + N+ G + TV+V
Sbjct: 25666 VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 25725
Query: 571 KVPPQPP--ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKREHG--DWEELQVEAG 625
P PP L V A+ +L W+ DGG+ I Y+I KRE W ++ E
Sbjct: 25726 LDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIE-KRETSRLSWTQVSTEVQ 25784
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD-----IVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A N+ G G P + + Y P P+ S IT +
Sbjct: 25785 ALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVS-AITKD 25843
Query: 681 TTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQL 740
+ VT W DGG I +++E R+ +W N T+ V+GLT Y+
Sbjct: 25844 SMVVT-WARPVDDGGTEIEGYILEKRDKEGVRW-TKCNKKTLTDLRLRVTGLTEGHSYEF 25901
Query: 741 RITAHNNAG 749
R+ A N AG
Sbjct: 25902 RVAAENAAG 25910
Score = 108 bits (260), Expect = 9e-23
Identities = 158/700 (22%), Positives = 270/700 (38%), Gaps = 47/700 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYK-EAPESWPSTPQKVIVPGSV 127
P P +V D + + W+ P G S + YIV+YK E E W K +
Sbjct: 17348 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEV---RG 17404
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T V L+ Y R+ A N G EP + V ++ P D++++A ++
Sbjct: 17405 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSP--DLQLDASVRDRIV 17462
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V R I+ Y G + + P A T+E + S +
Sbjct: 17463 VHAGGVIR------IIAYVSGKPPPTVTWNMNERTLPQEA-----TIETTAISSSMVIKN 17511
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ H V + ++ + DVP + L+++S +++W P
Sbjct: 17512 CQRSHQG----VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 17567
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I V +D VT ++ + T+ GL + Y + A + G
Sbjct: 17568 EDDGGSPITN--YVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIG 17624
Query: 368 DG--VRAAPVYCHTEE-DVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSV 423
G V + E VP P D++ ++N + ++W PP G ++ Y L +
Sbjct: 17625 MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRL 17684
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRA--THQFWVSASTRLGEGE---ATRVVTVLP 478
I G E+ HK + + + LS + + + T+++ VSA +G+G+ T+ +T
Sbjct: 17685 I--GTEK-FHK-VTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKD 17740
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGT 537
+ P F + E +L+ G P P +W + + R ++ ++ T
Sbjct: 17741 ELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPAT 17800
Query: 538 LTISMTQS--ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW 593
L + ++ +DSG Y VEN G + V V P PP+ ++ + D + + W
Sbjct: 17801 LALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISW 17860
Query: 594 SDQ-GDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
DGGS I Y+I K D W + + + + L G Y I A N G
Sbjct: 17861 KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYG 17920
Query: 652 TGLP--CDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMS 709
P D + A + VP P + + + V + DGG I +++E RE
Sbjct: 17921 ISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETM 17980
Query: 710 QPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+W V+ F V L Y+ R++A N G
Sbjct: 17981 SKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIG 18020
Score = 108 bits (260), Expect = 9e-23
Identities = 122/487 (25%), Positives = 195/487 (40%), Gaps = 32/487 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P PP L+ ++ SV ++W+PP + G + I + Y V T A +
Sbjct: 22877 DTPG-PPQDLKVKEVTKTSVTLTWDPPLLDGGSKI-KNYIVEKREST-----RKAYSTVA 22929
Query: 341 SGLHTT---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ H T + L+ +Y V A G G+ A + P P I +R
Sbjct: 22930 TNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTR 22989
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
N + +SW P G ++GY + M + ++ +T++ +
Sbjct: 22990 NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEE----YS 23045
Query: 457 FWVSASTRLGEGEATRV-VTVLPSDSV-PARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
F VSA G + ++ V V+ D V P E++ + +G P PA
Sbjct: 23046 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPA 23105
Query: 515 TTWTMNGVGLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW + V L+ T R N S + LTI D G+Y + N G T V V
Sbjct: 23106 VTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVL 23165
Query: 572 VPPQPPI--LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHG--DWEELQVEAGT 626
P PP + + + ADS+ L W + DGGS I Y++ KR+ W+ +
Sbjct: 23166 DKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE-KRDTSTTTWQIVSATVAR 23224
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG--TGLPCDIVHAYTKGTVPVKPKHSQMITLNT--T 682
+ L G YQ I A NR G T L + A VP P + ++TL++ +
Sbjct: 23225 TTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP-GPPGTPVVTLSSRDS 23283
Query: 683 TVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
W + DGG ++ + +E +E + W + N + F +GL Y+ R+
Sbjct: 23284 MEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTKFKTTGLEEGVEYEFRV 23342
Query: 743 TAHNNAG 749
+A N G
Sbjct: 23343 SAENIVG 23349
Score = 105 bits (253), Expect = 7e-22
Identities = 108/394 (27%), Positives = 164/394 (41%), Gaps = 19/394 (4%)
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEG 431
PV+ PS P + +A ++ N + ++W PP G ++GY + Y V ++
Sbjct: 18030 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 18089
Query: 432 THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVT-VLPSDSV--PARI-- 486
H P T ++ + T++F V A GE + V VL D + P I
Sbjct: 18090 NHTPESCPET-KYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILD 18148
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQS 545
+ +R + + LS GVP P TW + R +V+ G+ L I
Sbjct: 18149 ANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAH 18208
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPI 603
D G Y+ +VEN G V+ V V P PP L V + DS +L W + DGGS I
Sbjct: 18209 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 18268
Query: 604 LGYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---V 659
YV+ + W L + H +L G +Y + A N+ G G + +
Sbjct: 18269 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPI 18328
Query: 660 HAYTKGTVPVKPKHSQMITLNTTTVT-VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN 718
A P PK + ++ T V+ VW DGG I +++EY+E W +
Sbjct: 18329 KALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW-IKFK 18387
Query: 719 SVQATERVFSVSGLTPAAHYQLRITAHNNAGHAL 752
+V E V V+GL Y+ R+ A N G L
Sbjct: 18388 TVTNLECV--VTGLQQGKTYRFRVKAENIVGLGL 18419
Score = 105 bits (253), Expect = 7e-22
Identities = 161/683 (23%), Positives = 267/683 (39%), Gaps = 54/683 (7%)
Query: 95 AGNSPIINYI-VQYKEAPESWPSTPQKVIVPGSVT------SASVQNLQPAT---SYHLR 144
AG++ ++N I + K P+S S K I P +T ++S+ ++ AT +
Sbjct: 21319 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 21378
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I A N G + V+VT + VP GPP V + S+ + +TW PP D G+ +
Sbjct: 21379 ITATNPFGTKV--EHVKVTVLD-VP-GPPGPVEISNVSAEKATLTWTPPLED--GGSPIK 21432
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y+ L T S + TV R + L + Y V A N
Sbjct: 21433 SYI----LEKRET----------SRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNH 21478
Query: 265 RXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
++ P PP + + ++ + VSW+ P G + I GY V
Sbjct: 21479 YGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEIT-GYHVER 21537
Query: 324 APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV 383
A+ +S L ++GL+ + Y V A AG G + +D
Sbjct: 21538 REKKSLRWVR-AIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 21596
Query: 384 ---PSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLS 438
P P++ +++ ++W P G+ + GY + + V ++ + T L
Sbjct: 21597 AYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 21656
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLPSDSVP--ARITSFSRNIV 494
+ ++ + + F +SA G GE + V ++ + P R +V
Sbjct: 21657 ITQFVVPDLQTKEK--YNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLV 21714
Query: 495 TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSADSGNYTC 553
+I + G PAP TWT + + L++ +N S L I D+G +
Sbjct: 21715 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 21774
Query: 554 SVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYK 611
++EN G+ V V P P + L D DS+ L W DGGS I Y++ K
Sbjct: 21775 TIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVE-K 21833
Query: 612 RE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV 669
RE + + + + L G Y + A N G G P + P
Sbjct: 21834 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 21893
Query: 670 KPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
P ++ + +TV++ W DGG I +VIE + QW ++ +V+ E V
Sbjct: 21894 PPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT-TVKGLECV-- 21950
Query: 729 VSGLTPAAHYQLRITAHNNAGHA 751
V LT Y ++ A N+AG +
Sbjct: 21951 VRNLTEGEEYTFQVMAVNSAGRS 21973
Score = 104 bits (249), Expect = 2e-21
Identities = 115/486 (23%), Positives = 191/486 (39%), Gaps = 35/486 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PP L+ + + S ++W+ P G ++ Y V V + + T + H
Sbjct: 18239 PPRDLEVSEIRKDSCYLTWKEPLDDG-GSVITNYVVERRDVASAQWSPLSATSKKKS-HF 18296
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGV---RAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
L Y V A G G P+ P P D+ + ++ +
Sbjct: 18297 A-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSL 18355
Query: 403 SWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHK--RMLSPSTLSHETSRSPPRATHQFWV 459
W P G + GY + + +EEGT + + + L + T++F V
Sbjct: 18356 VWNKPDRDGGSPITGYLV------EYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRV 18409
Query: 460 SASTRLGEGEATRVVTVLPSDS-VPARI---TSFSRNIVTPWKENISLSCNKVGVPAPAT 515
A +G G + + + VP + +V + GVP P
Sbjct: 18410 KAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTA 18469
Query: 516 TWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
WT +G +++ V +D LTI D+G Y +V N G V + V
Sbjct: 18470 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD 18529
Query: 573 PPQPPI--LAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTSE 628
P PP + ++D + + + W + DGGSP++ Y++ + D W + + ++
Sbjct: 18530 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTK 18589
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDIV-----HAYTKGTVPVKPKHSQMITLNTTT 683
+P+L G Y + A N+IG G P D H ++ + P KP + IT N T
Sbjct: 18590 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAAT 18648
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
V+ W DGG I + +E RE++ +W V N + F V+GL Y+ R+
Sbjct: 18649 VS-WTLPKSDGGSPITGYYMERREVT-GKWVRV-NKTPIADLKFRVTGLYEGNTYEFRVF 18705
Query: 744 AHNNAG 749
A N AG
Sbjct: 18706 AENLAG 18711
Score = 101 bits (241), Expect = 2e-20
Identities = 124/508 (24%), Positives = 191/508 (37%), Gaps = 54/508 (10%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY----RVTYAPVTDWYGNEDAVTKQIS 341
PPG + A + S+ VSW PP G + I GY R +P +
Sbjct: 16528 PPGKPKVLARTKGSMLVSWTPPLDNGGSPIT-GYWLEKREEGSPYWSRVSRAPITKVGLK 16586
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSRN 398
G+ + L Y A AAG G + P D P P+ + +++
Sbjct: 16587 GVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKS 16646
Query: 399 KILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTH--KRMLSPSTLSHETSRSPPRAT- 454
I + W PP+ G + GY + M +EEGT KR+ P L P
Sbjct: 16647 SISLGWKPPAKDGGSPIKGYIVEM------QEEGTTDWKRVNEPDKLITTCECVVPNLKE 16700
Query: 455 ---HQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF-----SRNIVTPWKENISLSCN 506
++F V A GE E + +P+ + F +V I +
Sbjct: 16701 LRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAV 16760
Query: 507 KVGVPAPATTWTMNGVGL-----------ESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
G P P ++W +G E + + + I + + +G Y+ +
Sbjct: 16761 IKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITA 16820
Query: 556 ENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKRE 613
+N G+ V+V P PP L V D S L W DGG I GYVI +
Sbjct: 16821 KNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI 16880
Query: 614 HGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT------KGT 666
G W ++ + G++ V+P+L +Y + A NR G G P + + T
Sbjct: 16881 DGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPD 16940
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEY-----REMSQPQWRLVSNSVQ 721
P+K K +IT NT ++ W DGG + ++++E + WR N
Sbjct: 16941 PPIKLKIG-LITKNTVHLS-WKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWR-QCNKRD 16997
Query: 722 ATERVFSVSGLTPAAHYQLRITAHNNAG 749
E F+V L Y+ R+ A N AG
Sbjct: 16998 VEELQFTVEDLVEGGEYEFRVKAVNAAG 17025
Score = 100 bits (240), Expect = 2e-20
Identities = 152/646 (23%), Positives = 251/646 (38%), Gaps = 54/646 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS SV++ S + + A+N G+ + V+V P GP V + ++ +
Sbjct: 23526 TSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGP---VVISGVTAEKCT 23582
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP +D +I+ Y V +E S V TV A ++
Sbjct: 23583 LAWKPPLQD-GGSDIINYIVERRE---------------TSRLVWTVVDANVQTLSCKVT 23626
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWE 305
L + Y + A N VP P A + ++ S+ V WE
Sbjct: 23627 KLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK-APEVTTVTKDSMIVVWE 23685
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + + I L ++GL +Y V A A
Sbjct: 23686 RPASDGGSEIL-GY-VLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENA 23743
Query: 366 AGDGVRAAP-VYCHTEEDV--PSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYM 421
AG + P Y + + P P + K +R+ + +SW P G + GY +
Sbjct: 23744 AGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEK 23803
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVV-TV 476
+ G E T M +P T ++T+ + + + F + A + G GE V +
Sbjct: 23804 CDVSVG--EWT---MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPI 23858
Query: 477 LPSDSVPARITSFS---RNIVTPWKE-NISLSCNKVGVPAPATTW-TMNGVGLESTLRKN 531
+ + + A R I+ ++ L G P P W ++G ++ +
Sbjct: 23859 IVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV 23918
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLH 590
SS +L + DSG YT ++EN G TV V P PP+ L V + DS+
Sbjct: 23919 TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVS 23978
Query: 591 LQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAF 647
+ W DGGS I Y++ KRE + + + + L G Y +TA
Sbjct: 23979 ITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAE 24037
Query: 648 NRIGTGLPCDIVHAYTKGTVPVKPKHSQM--ITLNTTTVTVWLDSWGDGGCGILYFVIEY 705
N G GLP VP P + +T N+ +++ W DGG I+ +++E
Sbjct: 24038 NEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLS-WTKPEHDGGSKIIQYIVEM 24096
Query: 706 REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
+ +W + V++ + V ++ LT Y R+ A N G +
Sbjct: 24097 QAKHSEKWSECAR-VKSLQAV--ITNLTQGEEYLFRVVAVNEKGRS 24139
Score = 99 bits (238), Expect = 4e-20
Identities = 114/432 (26%), Positives = 175/432 (40%), Gaps = 31/432 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
++GL Y V A G G V P+ P++P + +++ I + W
Sbjct: 16183 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDW 16242
Query: 405 LPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
P S G + GY + + E +KR L P+T S ++F V A
Sbjct: 16243 KEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR-LCPTT-SFLVENLDEHQMYEFRVKAVN 16300
Query: 464 RLGEGEATRVVTV-LPSDSVPA----RITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
+GE E + + V + D VP R++ I E + + + G+P P W+
Sbjct: 16301 EIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWS 16360
Query: 519 MNGVGLESTL------RKNVS-SDGTLTISMTQSA--DSGNYTCSVENIHGRDEVTYTVE 569
N +E ++ VS S+ +S+ ++ D G YT + N G VE
Sbjct: 16361 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVE 16420
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYK---REHGDWEELQVEA 624
V P PP LAV D A+S +L W D GGS I YVI+ + R+ +WEE+ A
Sbjct: 16421 VYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTA 16480
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
+ + L +Y+ + A N+ G C D V +P P +++
Sbjct: 16481 VEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKG 16540
Query: 683 TVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS----VQATERVFSVSGLTPAAH 737
++ V W +GG I + +E RE P W VS + V F+V L
Sbjct: 16541 SMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVK 16600
Query: 738 YQLRITAHNNAG 749
YQ R A N AG
Sbjct: 16601 YQFRAMAINAAG 16612
Score = 99 bits (238), Expect = 4e-20
Identities = 122/491 (24%), Positives = 192/491 (39%), Gaps = 36/491 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVT 337
D P P L+ + ++ S VSW PP G G +VT+ V + VT
Sbjct: 19624 DTPG-PVSDLKVSDVTKTSCHVSWAPPENDG------GSQVTHYIVEKREADRKTWSTVT 19676
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAV 394
++ ++ L Y V A G GV PV P P ++
Sbjct: 19677 PEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTE 19736
Query: 395 SSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
++N ++WLPP G + GY E + T ++ +L + +
Sbjct: 19737 MTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKK- 19795
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFSRNIVTPWKENISLSCNKVGVP 511
++F V+A +G V + +P +I + + K+ + + + G P
Sbjct: 19796 -YKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKK-LRIEAHVYGKP 19853
Query: 512 APATTWTM--NGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
P W + V S L + S L I DSG Y+ + EN G D V
Sbjct: 19854 HPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKV 19913
Query: 569 ---EVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVI-NYKREHGDWEELQVE 623
+ PPQPP + D AD+ L W DGGS I Y++ GDW
Sbjct: 19914 VVMDAPGPPQPP-FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 19972
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC---DIVHAYTKGTVPVKPKHSQMITLN 680
+ + L G Y + A NR G P +V + G VP +PK++++ +N
Sbjct: 19973 VTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG-VPSEPKNARVTKVN 20031
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS-VQATERVFSVSGLTPAAHY 738
+ V W DGG I+ ++IE +E + W +++ V++TE + +GL Y
Sbjct: 20032 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTE--YPCAGLVEGLEY 20089
Query: 739 QLRITAHNNAG 749
RI A N AG
Sbjct: 20090 SFRIYALNKAG 20100
Score = 98.7 bits (235), Expect = 1e-19
Identities = 146/663 (22%), Positives = 262/663 (39%), Gaps = 59/663 (8%)
Query: 118 PQKVIVPGSVTSAS--VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ+ + + S+S ++N Q + ++A+N G+ + + V V P G P
Sbjct: 17493 PQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFL 17551
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
S +L TW P+ D I Y + +E + + + +YTV
Sbjct: 17552 AHNLTNESCKL--TWFSPEDD-GGSPITNYVIEKRESDRRAWTPV-------TYTV---- 17597
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PGALQCN 293
R T+ GL + AY + A NS + + ++P P L+
Sbjct: 17598 ----TRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVK 17653
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
++ +V ++W PP G + I+ + T+ + + T+ GL+
Sbjct: 17654 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF--HKVTNDNLLSRKYTVKGLKEG 17711
Query: 354 TNYSVTVCAFTAAGDGVRA---APVYCHTEEDVPSAPADIKAAVSSR--NKILVSWLPPS 408
Y V A G G + P+ C E P+ D + ++ R ++
Sbjct: 17712 DTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSG 17771
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
P + + V+ED R TH + +P+TL+ E ++ + ++ V G
Sbjct: 17772 KPKPKVSWFKDEADVLEDDR---THIKT-TPATLALEKIKAKRSDSGKYCVVVENSTGSR 17827
Query: 469 EATRVVTVLPSDSVPARITSFSR----NIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
+ V V+ P SF +V WK + +K+ V +
Sbjct: 17828 KGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM 17887
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE--VTYTVEVK----VPPQPPI 578
T + S+ T +S + EN++G + V+ +++ K VP P
Sbjct: 17888 PVT---SASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQ 17944
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD--WEELQVEA--GTSEHVLPNL 634
V + DS + W+ DGG PI Y++ KRE W + + ++ +P+L
Sbjct: 17945 PIVTEVTKDSALVTWNKPHDGGKPITNYILE-KRETMSKRWARVTKDPIHPYTKFRVPDL 18003
Query: 635 WCGTRYQLYITAFNRIGTG---LPCDIVHAYTKGTVPVKPKHSQMI--TLNTTTVTVWLD 689
G +Y+ ++A N IG G P V A P P + + I T N+ +T W
Sbjct: 18004 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLT-WQP 18062
Query: 690 SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA-TERVFSVSGLTPAAHYQLRITAHNNA 748
DGG IL +++EY+++ +WR +++ ++ E + V+GL Y+ R+ A N A
Sbjct: 18063 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 18122
Query: 749 GHA 751
G +
Sbjct: 18123 GES 18125
Score = 97.5 bits (232), Expect = 2e-19
Identities = 125/500 (25%), Positives = 198/500 (39%), Gaps = 38/500 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L+ + ++ S R+SW+ P G + I +GY + + + V
Sbjct: 16837 DVPG-PPKDLKVSDITRGSCRLSWKMPDDDGGDRI-KGYVIEKRTIDGKAWTK--VNPDC 16892
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV---PSAPADIKAAVSSR 397
+ L Y V A G G + T D P P +K + ++
Sbjct: 16893 GSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITK 16952
Query: 398 NKILVSWLPPSSPNGVLVGYTLYMSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRA 453
N + +SW PP + G V + + + D +E L
Sbjct: 16953 NTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGG 17012
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKE--NISLSCNKVGV 510
++F V A G + + TV P D P S +E N+++ GV
Sbjct: 17013 EYEFRVKAVNAAGVSKPS--ATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGV 17070
Query: 511 PAPATTW---------TMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
P P TW V ++ + K V D TL I ++ +D+G YT + N G
Sbjct: 17071 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 17130
Query: 561 RDEVTYTVEVKVPPQPPI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHG-- 615
+ V P PP+ + AD + L W + DGGS I YVI KRE
Sbjct: 17131 TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE-KREANRK 17189
Query: 616 DWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKPKH 673
W + E + +P L G Y I A N+ G G P D + +VP P
Sbjct: 17190 TWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDK 17249
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVS-NSVQA-TERV-FSV 729
+ ++ ++TV W + DGG + + +E ++ + +W+ V+ + ++A T V + V
Sbjct: 17250 PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKV 17309
Query: 730 SGLTPAAHYQLRITAHNNAG 749
+GL + YQ R+ A N AG
Sbjct: 17310 TGLIEGSDYQFRVYAINAAG 17329
Score = 96.3 bits (229), Expect = 5e-19
Identities = 161/715 (22%), Positives = 271/715 (37%), Gaps = 69/715 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P+ P +I ID + +SW P G S I NYIV+ + W + V +
Sbjct: 19922 PQPPFDISDIDADA--CSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV----TK 19975
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP-SQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
TS V L P Y R+ AENR G SEP + P V P++ RV + +
Sbjct: 19976 TSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCI 20035
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
V W+ P D I+GY + +E NS V VR+ E
Sbjct: 20036 FVAWDRPDSD-GGSPIIGYLIERKERNSLLWVK------ANDTLVRSTE--------YPC 20080
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL + Y+ + A N +P PPG + ++ +V + W
Sbjct: 20081 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTAR-MPVDPPGKPEVIDVTKSTVSLIWAR 20139
Query: 307 PPMRGRNGILQGYRVTYAPVT-DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + I+ GY V + D + + QI T +GL Y A TA
Sbjct: 20140 PKHDGGSKII-GYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTA 20198
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ P T + P I +V+ ++ + V + + G + +S
Sbjct: 20199 VNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK 20257
Query: 425 EDGR----EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD 480
+DG EG K + + + E + + + ++A G AT + VL
Sbjct: 20258 KDGTLLKPAEGI-KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 20316
Query: 481 SVPARIT---SFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
PA + +S + W+ + +++ T + ++ VS+
Sbjct: 20317 GPPASVKINKMYSDRAMLSWEPPLEDGGSEI------TNYIVDKRETSRPNWAQVSATVP 20370
Query: 538 LTISMTQSADSGN---YTCSVENIHGRDEVTYTVEVKV-----PP---QPPILAVVDSYA 586
+T + G+ + EN +G + +T PP PP+++ +
Sbjct: 20371 ITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITK-- 20428
Query: 587 DSLHLQWSDQGD-GGSPILGYVINYKREHG-DWEELQVEAGTSEHV-LPNLWCGTRYQLY 643
D + + W D GGSPI GY++ + +W ++ + + L GT Y+
Sbjct: 20429 DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFR 20488
Query: 644 ITAFNRIGTGLPCDIVH-AYTKGT--VPVKPKHSQMITLNTTTVTVWLDSWG----DGGC 696
+TA N+ G G P D AY + P P ++ ++V++ SWG DGG
Sbjct: 20489 VTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSVSL---SWGKPAYDGGS 20545
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
I+ +++E + W + + F V+GL YQ R+ A N G++
Sbjct: 20546 PIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYS 20600
Score = 96.3 bits (229), Expect = 5e-19
Identities = 120/487 (24%), Positives = 189/487 (38%), Gaps = 34/487 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYGNEDAVTKQISGL 343
PP ++ +S+ V W P G + ++ GY + W V +
Sbjct: 27599 PPSTPWVTNVTRESITVGWHEPVSNGGSAVV-GYHLEMKDRNSILWQKANKLVIRTTHFK 27657
Query: 344 HTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
TT+S GL Y V A AAG G + P D P +++ S+N + +
Sbjct: 27658 VTTISAGLI----YEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSL 27713
Query: 403 SWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
SW P+ G + GY + + DGR T + + S + ++F V A
Sbjct: 27714 SWQQPAFDGGSKITGYIVERRDLPDGR--WTKASFTNVTETQFIISGLTQNSQYEFRVFA 27771
Query: 462 STRLGE----GEATRVVTVLPSDSVPARITSFSRNIVTPWK--ENISLSCNKVGVPAPAT 515
+G E +T + S P V ++ ++ L G PAP
Sbjct: 27772 RNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTI 27831
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVTYTVEVKV 572
W + L++ V + L + + AD SG Y + N G T V++
Sbjct: 27832 EWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILD 27891
Query: 573 PPQPP--ILAVVDSYADSLHLQWSDQG-DGGSPILGYVINYKREHGDWEELQVEAGTSEH 629
P PP + A+ + L W DGG+ I Y++ KRE V E
Sbjct: 27892 KPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE-KRETSRVVWSMVSEHLEEC 27950
Query: 630 VL--PNLWCGTRYQLYITAFNRIGTGLP--CDIVHAYTKGTVPVKPKHSQM--ITLNTTT 683
++ + G Y + A N+ G G P D V A P P ++ IT N+ T
Sbjct: 27951 IITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMT 28010
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V VW DGG I + +E R+ W +++ +++ T + V+GLT + YQ R+
Sbjct: 28011 V-VWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ--KVTGLTENSDYQYRV 28067
Query: 743 TAHNNAG 749
A N AG
Sbjct: 28068 CAVNAAG 28074
Score = 95.1 bits (226), Expect = 1e-18
Identities = 118/485 (24%), Positives = 192/485 (39%), Gaps = 28/485 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQI 340
P PP + ++ S+ V W P G + I+ Y V D G K +
Sbjct: 22581 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN-YIVERR---DKAGQRWIKCNKKTL 22636
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA--APVY--CHTEEDVPSAPADIKAAVSS 396
+ L +SGL Y + A AAG + +P Y C T P P + + +S
Sbjct: 22637 TDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFK-PGPPGNPRVLDTS 22695
Query: 397 RNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
R+ I ++W P G + GY + +++ E+ + +T S+ + +
Sbjct: 22696 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT-SYTITGLTENQEY 22754
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDS--VPARITSFS--RNIVTPWKE-NISLSCNKVGV 510
+ + A G GE V ++ +P I + R +VT + L G
Sbjct: 22755 KIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGR 22814
Query: 511 PAPATTWTMN-GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
PAP W + G L+ ++ SS L + DSG Y +VEN G V
Sbjct: 22815 PAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVR 22874
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKRE--HGDWEELQVEAG 625
V P PP L V + S+ L W DGGS I Y++ KRE + +
Sbjct: 22875 VLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCH 22933
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ + L G Y + A N G GLP + + P+ P ++ + +V+
Sbjct: 22934 KTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVS 22993
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG IL +++E + +W + +V+ TE +++GL Y R++A
Sbjct: 22994 LSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA-TVKVTEA--TITGLIQGEEYSFRVSA 23050
Query: 745 HNNAG 749
N G
Sbjct: 23051 QNEKG 23055
Score = 93.9 bits (223), Expect = 3e-18
Identities = 134/613 (21%), Positives = 230/613 (37%), Gaps = 52/613 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T +VP P + + + + ++W+PP+ D ++ Y V Q+ ++ +++SG
Sbjct: 18526 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDD-GGSPVINYIVEKQDTRKDTWGVVSSG 18584
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV- 282
+++++ + LQK Y V+A N
Sbjct: 18585 ---------------SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFS 18629
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ-IS 341
P PPG ++ + VSW P G + I GY + VT G V K I+
Sbjct: 18630 PPSPPGKPVVTDITENAATVSWTLPKSDGGSPIT-GYYMERREVT---GKWVRVNKTPIA 18685
Query: 342 GLHTTLSGLRRYTNYSVTVCAFTAAG---DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
L ++GL Y V A AG + P+ P P + K SR
Sbjct: 18686 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRE 18745
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRAT--- 454
+ W P S G ++GY V+E + ++ L + + P
Sbjct: 18746 TADLVWTKPLSDGGSPILGY-----VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGN 18800
Query: 455 -HQFWVSASTRLGEGEATRVV-TVLPSDSV---PARITSFSRNIVTPWK-ENISLSCNKV 508
++F + A+ +GEGE + +V+ D + + R+++T + I +
Sbjct: 18801 EYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVK 18860
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSD---GTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TWT G L R ++ D L I AD G Y S +N G + +
Sbjct: 18861 GRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGS 18920
Query: 566 YTVEVKVPPQP-PILAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKREHGDWEELQVE 623
V V P P L V + ++ + W + D GGS I +++ Y++ + +
Sbjct: 18921 AIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS 18980
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLN 680
T + NL Y + A N++G G + + A P +P++ +
Sbjct: 18981 DVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKG 19040
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHY 738
T V + W DGG L + +E R W R+ S++ T + V Y
Sbjct: 19041 KTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETH--YMVDRCVENQIY 19098
Query: 739 QLRITAHNNAGHA 751
+ R+ N G +
Sbjct: 19099 EFRVQTKNEGGES 19111
Score = 92.3 bits (219), Expect = 9e-18
Identities = 141/624 (22%), Positives = 238/624 (38%), Gaps = 59/624 (9%)
Query: 148 ENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
EN G+ E + V+V T GPP +V V+ S VTWEPP D I+ Y V
Sbjct: 20696 ENSCGKKEYTIVVKVLDTP----GPPVNVTVKEISKDSAYVTWEPPIID-GGSPIINYVV 20750
Query: 208 GFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXX 267
++ S + + S+ V + L++ +Y V A N
Sbjct: 20751 QKRDAERKSWSTVTTECSKTSFRV---------------ANLEEGKSYFFRVFAENEYGI 20795
Query: 268 XXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVT 327
P P L+ ++S S + W+ P G + I+ GY V +
Sbjct: 20796 GDPGETRDAVKASQTPG-PVVDLKVRSVSKSSCSIGWKKPHSDGGSRII-GYVVDFLTEE 20853
Query: 328 DWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP 387
+ + V K +S L + L Y+ V A G+G + + +DV +
Sbjct: 20854 NKW---QRVMKSLS-LQYSAKDLTEGKEYTFRVSAENENGEGT-PSEITVVARDDVVAPD 20908
Query: 388 ADIKAA-----VSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
D+K ++ N +P V + + ++ + +
Sbjct: 20909 LDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLI 20968
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENIS 502
++ +S ++ ++ G E T + V+ +P F VT +
Sbjct: 20969 VYDCQKSD---AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDE--VTAEAMTLK 21023
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTL---TISMTQSADSGNYT--CSVEN 557
+ K + T + + +S K V+ + T +T+ + YT S EN
Sbjct: 21024 WAPPKDDGGSEITNYILEK--RDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAEN 21081
Query: 558 IHGRDEVTYTVEV------KVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINY 610
+G E + + VP PP +VD DS+ L W+D + GGSPI GY + +
Sbjct: 21082 KYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEF 21141
Query: 611 KREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG---LPCDIVHAYTKG 665
K + W+ + + + L G Y+ + A N G G LP + V A
Sbjct: 21142 KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPI 21201
Query: 666 TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATER 725
P KP+ IT N+ T+ +W + DGG + +++E R++ W + +N V E
Sbjct: 21202 DPPGKPEVIN-ITRNSVTL-IWTEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPEC 21258
Query: 726 VFSVSGLTPAAHYQLRITAHNNAG 749
F+V+ L Y+ RI A N AG
Sbjct: 21259 AFTVTDLVEGGKYEFRIRAKNTAG 21282
Score = 85.0 bits (201), Expect = 1e-15
Identities = 144/628 (22%), Positives = 236/628 (37%), Gaps = 65/628 (10%)
Query: 150 RLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGF 209
+L S S+ VT GPPQ++ V+ + WEPP D + Y +
Sbjct: 25023 KLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID-GGAKVKNYVIDK 25081
Query: 210 QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXX 269
+E + ++S S+ V L + A Y V A N
Sbjct: 25082 RESTRKAYANVSSKCSKTSFKVEN---------------LTEGAIYYFRVMAENEFGVGV 25126
Query: 270 XXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW 329
+ PS PPG + +S S + WE P G + +L GY V P
Sbjct: 25127 PVETVDAVKAAEPPS-PPGKVTLTDVSQTSASLMWEKPEHDGGSRVL-GYVVEMQPK--- 25181
Query: 330 YGNED-AVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG---VRAAPVYCHTEEDVPS 385
G E ++ + + ++GL Y V A+ G V PV PS
Sbjct: 25182 -GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPS 25240
Query: 386 APA-----DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPS 440
I+A + +I V P + + V G L + + E T S
Sbjct: 25241 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETAT-------S 25293
Query: 441 TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVL--PSDSV-PARITSFSRN-IVTP 496
T+ H ++ V+A+ G V VL P V P R S + +V
Sbjct: 25294 TVLH-IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 25352
Query: 497 WKENISLS-C---NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
W+ C N + TT T + V +T+ + T+ I+ ++ +
Sbjct: 25353 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVS--ATVART-----TIKITKLKTGTEYQFR 25405
Query: 553 CSVENIHGRDEV--TYTVEVKVP---PQPPILAVVDSYA-DSLHLQWSDQ-GDGGSPILG 605
EN +G+ + V V+ P P PP V S + D + +QW + DGG+ I+G
Sbjct: 25406 IFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIG 25465
Query: 606 YVINYKREHGD-WEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + K ++ W +L + ++ L G Y+ ++A N +G G P + +
Sbjct: 25466 YHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFV 25525
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
P + I + VT+ W DGG I +++E +++ +W + ++
Sbjct: 25526 ARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW-MKASFTNV 25584
Query: 723 TERVFSVSGLTPAAHYQLRITAHNNAGH 750
E F+VSGL Y+ R+ A N AG+
Sbjct: 25585 LETEFTVSGLVEDQRYEFRVIARNAAGN 25612
Score = 83.8 bits (198), Expect = 3e-15
Identities = 138/603 (22%), Positives = 226/603 (37%), Gaps = 55/603 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P++++V + ++ ++W P G S I NYIV+ +E+ ST V T
Sbjct: 22879 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYST---VATNCHKT 22935
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S V LQ SY+ R++AEN G P++ + E P PP + + + + +
Sbjct: 22936 SWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL-PPGKITLMDVTRNSVSL 22994
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+WE P+ D ILGY V Q S+ A TV+ E T++G
Sbjct: 22995 SWEKPEHD-GGSRILGYIVEMQTKGSDKWATCA--------TVKVTE--------ATITG 23037
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L + Y+ V A N + +D+ P L N + + P
Sbjct: 23038 LIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVP 23097
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GR + P+ +A + + + L T R + V V +AG+
Sbjct: 23098 FIGRPTPAVTWHKDNVPLKQ-TTRVNAESTENNSLLTIKDACREDVGHYV-VKLTNSAGE 23155
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
+ V + P+ P +K + + I +SW PP G + + I + R
Sbjct: 23156 AIETLNVIVLDKPGPPTGP--VKMDEVTADSITLSWGPPKYDGGSSIN-----NYIVEKR 23208
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRAT---HQFWVSASTRLG-------EGEATRVVTVLP 478
+ T + +T++ T ++ T +QF ++A R G E + +P
Sbjct: 23209 DTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVP 23268
Query: 479 SDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT 537
+T SR ++ W E IS ++V + N + L L K
Sbjct: 23269 GPPGTPVVTLSSRDSMEVQWNEPISDGGSRV-IGYHLERKERNSI-LWVKLNKTPIPQTK 23326
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV------PPQPPILAVVDSYADSLHL 591
+ + + S ENI G + + E V PP P +V +S+ L
Sbjct: 23327 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVT--RNSVTL 23384
Query: 592 QWSDQG-DGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
QW DGGS I GY++ K G W + H + L RY+ + A N
Sbjct: 23385 QWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARN 23444
Query: 649 RIG 651
G
Sbjct: 23445 AAG 23447
Score = 83.4 bits (197), Expect = 4e-15
Identities = 143/705 (20%), Positives = 258/705 (36%), Gaps = 52/705 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQKVIVPGS 126
+VP+ P V + + ++W +P+ G PI NYI++ +E + W + I P
Sbjct: 17937 RVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHP-- 17994
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST-- 184
T V +L Y R+ AEN +G +PS P + ++ + P V EA +T
Sbjct: 17995 YTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCN 18054
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ +TW+PP+ D ILGY V +Q++ A++T + ++
Sbjct: 18055 SVDLTWQPPRHD-GGSKILGYIVEYQKVGDEEW-------RRANHTPES-----CPETKY 18101
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++GL+ Y V A N+ ++D P L N Q ++V
Sbjct: 18102 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVG- 18160
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK---QISGLHTTLSGLRRYTNYSVTVC 361
+R + I++G V + VT + DA TK ++ + + L +R + +
Sbjct: 18161 --DTLR-LSAIIKG--VPFPKVTWKKEDRDAPTKARIDVTPVGSKLE-IRNAAHEDGGIY 18214
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
+ T D P P D++ + ++ ++W P G ++ T Y+
Sbjct: 18215 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI--TNYV 18272
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTVLP 478
D + SH + F V+A + G G E + + L
Sbjct: 18273 VERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 18332
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKV----GVPAPATTWTMNGVGLESTLRKNVSS 534
P V K +SL NK G P G + ++ +
Sbjct: 18333 PLHPPGPPKDLHH--VDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVT 18390
Query: 535 DGTLTISMTQSADSGNYTCSVENI--HGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQ 592
+ ++ Q + + ENI G + T +E + PP + + + L ++
Sbjct: 18391 NLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVK 18450
Query: 593 WSDQGDGGSPILGYVINYKREHGDWEELQ------VEAGTSEHVLPNLWCGTR--YQLYI 644
+ I G + + D E++ VE VL C R + I
Sbjct: 18451 AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 18510
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIE 704
T N G+ + P P + +T T++ W DGG ++ +++E
Sbjct: 18511 TVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS-WQPPKDDGGSPVINYIVE 18569
Query: 705 YREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + W +VS+ T+ + L Y R+ A N G
Sbjct: 18570 KQDTRKDTWGVVSSGSSKTK--LKIPHLQKGCEYVFRVRAENKIG 18612
Score = 82.2 bits (194), Expect = 9e-15
Identities = 65/247 (26%), Positives = 107/247 (43%), Gaps = 9/247 (3%)
Query: 511 PAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
P W L + + + I + D G Y ++N HG+ E ++V
Sbjct: 13954 PKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV 14013
Query: 571 -KVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKR-EHGDWEELQVEAGTS 627
VP L V +++ + L W + DGGS I+GYV+ + + W A +
Sbjct: 14014 IDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESC 14073
Query: 628 EHVLPNLW-CGTRYQLYITAFNRIGTGLPCDI---VHAYTKGTVPVKPKHSQMITLNTTT 683
E + L G Y ++A NR+GTG P + V A +K VP P + + +N
Sbjct: 14074 EFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFG 14133
Query: 684 VTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRI 742
V++ W DGG I +VIE R+ + +W + +V+A + +V+ + Y R+
Sbjct: 14134 VSLTWEPPEYDGGAEITNYVIELRDKTSIRWD-TAMTVRAEDLSATVTDVVEGQEYSFRV 14192
Query: 743 TAHNNAG 749
A N G
Sbjct: 14193 RAQNRIG 14199
Score = 81.4 bits (192), Expect = 2e-14
Identities = 122/561 (21%), Positives = 210/561 (37%), Gaps = 45/561 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N+ + + + ++ +SW P G + I NYIV+ +E +T + + T
Sbjct: 26126 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT---ITNNCTKT 26182
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+ ++NLQ SY+ R++A N G P++ + E P P + V+ +T I
Sbjct: 26183 TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI- 26241
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
WE P+ D I GY V Q S V+T+E T+SG
Sbjct: 26242 KWEKPESD-GGSKITGYVVEMQTKGSEK--------WSTCTQVKTLE--------ATISG 26284
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L Y V A N + D+ P L + + ++ P
Sbjct: 26285 LTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVP 26344
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+GR +R + + + +K ++ L + Y +C +AG
Sbjct: 26345 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE--LCVSNSAGS 26402
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
P+ D P P I+ S + I +SW PP G + + Y+ ++
Sbjct: 26403 --ITVPITI-IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQI--SNYIVEKKETT 26457
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE---GEATRVVTVLP-----SD 480
H + + S + R + +QF V A R G+ E++ VV P
Sbjct: 26458 STTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPP 26517
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
P + + ++ W+ ++ ++ V + L S K + +D + +
Sbjct: 26518 GTPKVVHATKSTMLVTWQVPVNDGGSR--VIGYHLEYKERSSILWSKANKILIADTQMKV 26575
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVE---VKVPPQPPILAVVDSYA-DSLHLQWS-D 595
S Y ENI G + + + E + P PP V + S+ L+WS
Sbjct: 26576 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKP 26635
Query: 596 QGDGGSPILGYVINYKREHGD 616
DGG+ I GY++ +RE D
Sbjct: 26636 HYDGGAKITGYIVE-RRELPD 26655
Score = 77.8 bits (183), Expect = 2e-13
Identities = 147/655 (22%), Positives = 236/655 (36%), Gaps = 78/655 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P + D + + ++W P G S I NY+V+ + E W V
Sbjct: 14711 PGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTV----KD 14766
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTEL 186
T+ L P Y R+ AEN G EP Q +T + P GPP + + +
Sbjct: 14767 TNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAV 14826
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP-GGASYTVRTVEGAGTARSRTT 245
+TW P D I GY+V + +++ V P +Y V+
Sbjct: 14827 TLTWCEPDDD-GGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVK------------- 14872
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
GL Y V A N ++D P PPG + SVR++
Sbjct: 14873 --GLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLN 14930
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT---LSGLRRYTNYSVTV 360
W P G ++ Y + G ++ V + G+ TT L GL YS V
Sbjct: 14931 WTKPEHDG-GAKIESYVIEMLKT----GTDEWV-RVAEGVPTTQHLLPGLMEGQEYSFRV 14984
Query: 361 CAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
A AG+ + PV C + PS P ++ ++N + W P G +
Sbjct: 14985 RAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPI-- 15042
Query: 418 TLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV-TV 476
T Y+ D R +G + + + + F V+A +G+ + T + +V
Sbjct: 15043 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSV 15102
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSC----NKVGVPAP----------ATTWTMNG- 521
L D+ ++ +V K ++ L N G P T W G
Sbjct: 15103 LAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGK 15162
Query: 522 -VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI-L 579
G + R +GT + A++ V + E+ + PP PP+ L
Sbjct: 15163 TAGPDCNFRVTDVIEGT-EVQFQVRAEN---EAGVGHPSEPTEILSIEDPTSPPSPPLDL 15218
Query: 580 AVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHGD-WEEL------QVEAGTSEHVL 631
V D+ + + W + +GGSPI+GY + + W + ++ E V+
Sbjct: 15219 HVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVV 15278
Query: 632 PNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV 686
P+ Y L + A N IG P +I ++ V P I L T + V
Sbjct: 15279 PD----KEYVLRVRAVNAIGVSEPSEI----SENVVAKDPDCKPTIDLETHDIIV 15325
Score = 77.8 bits (183), Expect = 2e-13
Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 8/142 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N+ V + + ++W P G SPIINY+VQ ++A +SW + V S
Sbjct: 20714 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST----VTTECSK 20769
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
TS V NL+ SY R+ AEN G +P + + P GP D++V + S +
Sbjct: 20770 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSCS 20828
Query: 188 VTWEPPQRDLWNGNILGYYVGF 209
+ W+ P D I+GY V F
Sbjct: 20829 IGWKKPHSD-GGSRIIGYVVDF 20849
Score = 76.2 bits (179), Expect = 6e-13
Identities = 87/323 (26%), Positives = 130/323 (40%), Gaps = 29/323 (8%)
Query: 76 IRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
+R + + + ISW P Y G I NYIV+ ++ + T V + T+ +
Sbjct: 25339 VRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTT---TWHMVSATVARTTIKITK 25395
Query: 135 LQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
L+ T Y RI AENR G+S P S+ V V + P GPP V + S +++V W
Sbjct: 25396 LKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP-GPPGTPFVTSISKDQMLVQWHE 25454
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
P D I+GY++ +E NS V + P + +TT GL +
Sbjct: 25455 PVND-GGTKIIGYHLEQKEKNSILWVKLNKTP------------IQDTKFKTT--GLDEG 25499
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y V A N D P PPG + ++ +V + W+ P G
Sbjct: 25500 LEYEFKVSAENIVGIGKPSKVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYDGG 25558
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD---- 368
+ I GY V + D + + T + T+SGL Y V A AAG+
Sbjct: 25559 SKI-TGYIVEKKDLPDGRWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAGNFSEP 25616
Query: 369 GVRAAPVYCHTEEDVPSAPADIK 391
+ + E D P+A D K
Sbjct: 25617 SDSSGAITARDEIDAPNASLDPK 25639
Score = 72.9 bits (171), Expect = 6e-12
Identities = 87/368 (23%), Positives = 141/368 (38%), Gaps = 25/368 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P+ + ++ TI + W +P + G SPI YI++ + + K + P T
Sbjct: 16222 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCP--TT 16279
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT-TTEEVPSGPPQDVRVEAKSSTELI 187
S V+NL Y R+ A N +G+SEPS P+ V +EVP P +R+ + T +
Sbjct: 16280 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP--PTIKLRLSVRGDTIKV 16337
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
EP ++ G + E + N TV+ P A + A++ ++
Sbjct: 16338 KAGEPVHIP---ADVTGLPMPKIEWSKNETVI--EKPTDALQITKEEVSRSEAKTELSIP 16392
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
+ V A N + D PS PP L + ++S ++W+ P
Sbjct: 16393 KAVREDKGTYTVTASN---RLGSVFRNVHVEVYDRPS-PPRNLAVTDIKAESCYLTWDAP 16448
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G + I Y + + + VT + L Y V A G
Sbjct: 16449 LDNGGSEITH-YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 16507
Query: 368 --DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYTLYMSVI 424
D ++ V +P P K ++ +LVSW PP G + GY L
Sbjct: 16508 ISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWL----- 16562
Query: 425 EDGREEGT 432
+ REEG+
Sbjct: 16563 -EKREEGS 16569
Score = 70.5 bits (165), Expect = 3e-11
Identities = 63/210 (30%), Positives = 86/210 (40%), Gaps = 8/210 (3%)
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQ-GDGGSPIL 604
D G Y VEN HG + TV V P PPI V D S+ +W DGGS I+
Sbjct: 15702 DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEII 15761
Query: 605 GYVINYKREHGDWEELQVEAGTSEHV---LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y + K + E V T H + L G Y + A NR G G PC
Sbjct: 15762 NYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL 15821
Query: 662 YTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
K P P + + + ++ V + D G IL + +E RE++ W V+ S
Sbjct: 15822 VAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKS 15881
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ + +V GL Y R+ A N AG
Sbjct: 15882 LLNALKA-NVDGLLEGLTYVFRVCAENAAG 15910
Score = 69.3 bits (162), Expect = 7e-11
Identities = 86/333 (25%), Positives = 135/333 (40%), Gaps = 38/333 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P N D + ++ W P G S IINY ++ K+ + P + + ++V ++
Sbjct: 15729 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTK--PDS-EWIVVTSTLR 15785
Query: 129 SA--SVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSST 184
SV L Y R+ AENR G P S+P+ P P + + VE +S
Sbjct: 15786 HCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPI-VEDVTSN 15844
Query: 185 ELIVTWEPPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
++V W P+ NG+ ILGY++ +E+NS S +++ A +
Sbjct: 15845 SMLVKWNEPKD---NGSPILGYWLEKREVNSTHW----------SRVNKSLLNA----LK 15887
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVR 301
+ GL + Y V A N+ D P PPG + SS ++
Sbjct: 15888 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD-PISPPGPPIPRVTDTSSTTIE 15946
Query: 302 VSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
+ WEPP G G + GY V V +W K I T+ +R +Y +
Sbjct: 15947 LEWEPPAFNG-GGEIVGYFVDKQLVGTNEW---SRCTEKMIKVRQYTVKEIREGADYKLR 16002
Query: 360 VCAFTAAGDGV--RAAPVYCHTEEDVPSAPADI 390
V A AAG+G PV ++ P+ D+
Sbjct: 16003 VSAVNAAGEGPPGETQPVTVAEPQEPPAVELDV 16035
Score = 69.3 bits (162), Expect = 7e-11
Identities = 135/600 (22%), Positives = 233/600 (38%), Gaps = 65/600 (10%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+SW P G S I NY+++ +EA ++W + P T ++ L Y RI
Sbjct: 17163 LSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSE---PKECTY-TIPKLLEGHEYVFRI 17218
Query: 146 IAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
+A+N+ G EP S+P VP G P V + + + V WE P+ D +
Sbjct: 17219 MAQNKYGIGEPLDSEPETARNLFSVP-GAPDKPTVSSVTRNSMTVNWEEPEYD-GGSPVT 17276
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
GY++ ++ S + P ++ A T ++GL + + Y V A N
Sbjct: 17277 GYWLEMKDTTSKRWKRVNRDP------IK----AMTLGVSYKVTGLIEGSDYQFRVYAIN 17326
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGA--LQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P PPG + + S + W PP G + + GY V
Sbjct: 17327 AAGVGPASLPSDPATARD-PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKV-TGYIV 17384
Query: 322 TYAP--VTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
Y +W +D K++ G ++GL+ Y V A AG G
Sbjct: 17385 EYKEEGKEEWEKGKD---KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIE 17441
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS-----VIEDGREEGT-- 432
+D +P D++ S R++I+V G ++ Y+S + E T
Sbjct: 17442 MKDRLVSP-DLQLDASVRDRIVVH-------AGGVIRIIAYVSGKPPPTVTWNMNERTLP 17493
Query: 433 HKRMLSPSTLSHETSRSPPRATHQ--FWVSASTRLGEGEATRVVTVLPSDSVPARI-TSF 489
+ + + +S + +HQ + + A GE + T +V VL VP + T F
Sbjct: 17494 QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL---DVPGPVGTPF 17550
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
+ +T ++ + +P T + + + V+ T + Q G
Sbjct: 17551 LAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQG 17610
Query: 550 N---YTCSVENIHGRDEVTYTVE-------VKVPPQPPILAVVDSYADSLHLQWS-DQGD 598
+ + EN G T E + VP +P L V + +++ L W+ + D
Sbjct: 17611 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 17670
Query: 599 GGSPILGYVINYKREHGDWEELQVEAG---TSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
GGS I+ YV+ R G + +V + ++ + L G Y+ ++A N +G G P
Sbjct: 17671 GGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 17729
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 7/158 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP PKN RV I ++W +P + G SPII Y+++ KE W ++
Sbjct: 20018 VPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLV---R 20074
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T L Y RI A N+ G S PS+P + T +P PP V + + +
Sbjct: 20075 STEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA-RMPVDPPGKPEVIDVTKSTV 20133
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP 224
+ W P+ D I+GY+V +L + V + P
Sbjct: 20134 SLIWARPKHD-GGSKIIGYFVEACKLPGDKWVRCNTAP 20170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 72/307 (23%), Positives = 114/307 (37%), Gaps = 27/307 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
VP P + + + + ++WT P G SPI +YI++ +E W + +
Sbjct: 21399 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 21458
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
V + +Q Y R+ A N G+ EP Q V + P GPP+ V +
Sbjct: 21459 VATKLIQG----NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNT 21514
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
V+W+ P D I GY+V +E S V P + R
Sbjct: 21515 ATVSWKRPVDD-GGSEITGYHVERREKKSLRWVRAIKTP--------------VSDLRCK 21559
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
++GLQ+ + Y V A N M+D P PP + +S ++
Sbjct: 21560 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 21619
Query: 304 WEPPPMRGRNGI-LQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W P G G+ + GY V + V D +D + + L+ Y+ + A
Sbjct: 21620 WGKPHYDG--GLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 21677
Query: 363 FTAAGDG 369
AG G
Sbjct: 21678 INDAGVG 21684
Score = 64.5 bits (150), Expect = 2e-09
Identities = 41/146 (28%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
+ VP P N+ + D + ++W P Y G + I NY+++ ++ W + + V
Sbjct: 14115 YDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTA---MTVR 14171
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVPSGPPQDVRVEAK 181
SA+V ++ Y R+ A+NR+G +PS V+V E PS PP ++ +
Sbjct: 14172 AEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQ 14230
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYV 207
+ + + + WEPP +D ILGY +
Sbjct: 14231 TQSSVQLKWEPPLKD-GGSPILGYII 14255
Score = 64.1 bits (149), Expect = 3e-09
Identities = 100/411 (24%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I ++ + S T+Q W +P Y G S I YIV+ KE PE W I+
Sbjct: 23369 PGRPEAI-IVTRNSVTLQ--WKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIID--- 23422
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R+IA N G SEPS+ +T +EV PP+ + ++ K
Sbjct: 23423 THFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEV--DPPR-ISMDPKYKDT 23479
Query: 186 LIV-TWE--PPQRDLWNGNI--LGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
++V E D++ I + + G QEL++ + + I S S +V+ +
Sbjct: 23480 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 23539
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+ + V V+ D P P G + + ++++
Sbjct: 23540 NYILKAKNVAGERSVTVNVKVL------------------DRPGPPEGPVVISGVTAEKC 23581
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
++W+PP G + I+ Y V + + DA + +S T L YT +
Sbjct: 23582 TLAWKPPLQDGGSDII-NYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMA 23640
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGYT 418
V + G+ + + PV VP AP + +++ ++V W P+S G ++GY
Sbjct: 23641 VNKY-GVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYV 23699
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L E R HKR++ L + ++F VSA G E
Sbjct: 23700 LEKRDKEGIRWTRCHKRLIGELRL--RVTGLIENHDYEFRVSAENAAGLSE 23748
Score = 63.7 bits (148), Expect = 3e-09
Identities = 67/260 (25%), Positives = 111/260 (42%), Gaps = 31/260 (11%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP +N+ V + + ++W +P G S II Y+V+ ++ ++W +
Sbjct: 14016 VPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRA----E 14071
Query: 127 VTSASVQNLQPA-TSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKS 182
+V LQ Y R+ A NR+G EP PV+ + +VP GPP +V + +
Sbjct: 14072 SCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVN 14130
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARS 242
+ +TWEPP+ D I Y + EL +++ + TVR +
Sbjct: 14131 RFGVSLTWEPPEYD-GGAEITNYVI---ELRDKTSI-----RWDTAMTVRAED------L 14175
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV---PSLPPGALQCNALSSQS 299
T++ + + Y+ V+A N + D PS PP L + + S
Sbjct: 14176 SATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSS 14234
Query: 300 VRVSWEPPPMRGRNGILQGY 319
V++ WEPP G + IL GY
Sbjct: 14235 VQLKWEPPLKDGGSPIL-GY 14253
Score = 63.3 bits (147), Expect = 5e-09
Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
Query: 572 VPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINY--KREHGDWEELQVEAGTS 627
V P PP I V +S+ + WS DGGS I GY + K+ G ++ L+ +
Sbjct: 27991 VTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDT 28050
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTV 684
+ L + YQ + A N G G P + A P P ++ +++
Sbjct: 28051 RQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSI 28110
Query: 685 TV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
T+ W DGG + +V+E R+ + +W VS + + VS L P +Y R++
Sbjct: 28111 TLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVS 28170
Query: 744 AHNNAG 749
A N AG
Sbjct: 28171 AVNCAG 28176
Score = 62.9 bits (146), Expect = 6e-09
Identities = 93/387 (24%), Positives = 149/387 (38%), Gaps = 41/387 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P+ PKN V ++ + W P + G S IINYIV+ ++ A + W +K +
Sbjct: 22582 PDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD--- 22638
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS--QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L Y RI+AEN G S PS P GPP + RV S +
Sbjct: 22639 LRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSS 22698
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ + W P D I GY V L I + P AG + T
Sbjct: 22699 ISIAWNKPIYD-GGSEITGYMVEI-ALPEEDEWQIVTPP------------AGLKATSYT 22744
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
++GL ++ Y + + A NS ED P L + ++R
Sbjct: 22745 ITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCT 22804
Query: 306 P---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTV 360
P++GR V +A D + D + + + +T L + R+ + +
Sbjct: 22805 LRLFVPIKGR----PAPEVKWA--RDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYIL 22858
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
++G ++A V D P P D+K ++ + ++W PP +L G +
Sbjct: 22859 TVENSSGS--KSAFVNVRV-LDTPGPPQDLKVKEVTKTSVTLTWDPP-----LLDGGSKI 22910
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETS 447
+ I + R E T K + +T H+TS
Sbjct: 22911 KNYIVEKR-ESTRKAYSTVATNCHKTS 22936
Score = 61.7 bits (143), Expect = 1e-08
Identities = 101/427 (23%), Positives = 151/427 (35%), Gaps = 28/427 (6%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQK 120
I + P P V + + W P Y G I Y ++ KE + K
Sbjct: 19315 IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNK 19374
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRV 178
+P VQNL P Y R+ AEN +G EPS P + ++ P GPP + RV
Sbjct: 19375 SAIPER--RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRV 19432
Query: 179 EAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAG 238
+ + + W P D I+GY V + AS G R A
Sbjct: 19433 VDTTKHSITLGWGKPVYD-GGAPIIGYVV-----EMRPKIADASPDEGWK---RCNAAAQ 19483
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQ 298
R T++ L ++ Y V A N +++ L P + +A S +
Sbjct: 19484 LVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI--LEPPEIDLDA-SMR 19540
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDW--YGNEDAVTKQISGLHTTLSGL--RRYT 354
+ + P+R + R AP W G ++ V K L T++ L T
Sbjct: 19541 KLVIVRAGCPIR----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNST 19596
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
+ T A D P +D+K + ++ VSW PP + G
Sbjct: 19597 RDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQ 19656
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV- 473
V + + D + T + T H T+ P + F V+A G G T V
Sbjct: 19657 VTHYIVEKREADRKTWSTVTPEVK-KTSFHVTNLVPGN-EYYFRVTAVNEYGPGVPTDVP 19714
Query: 474 VTVLPSD 480
VL SD
Sbjct: 19715 KPVLASD 19721
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 4/134 (2%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQK 120
+ + +VP P +V ++ ISW +P + G SPI+ Y V+ KE T K
Sbjct: 22178 VANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSK 22237
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
+VPG++ +S L +Y R+IAEN G+S+PS+P + + P + V +
Sbjct: 22238 ALVPGNIFKSS--GLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNI 22295
Query: 181 KSSTELIVTWEPPQ 194
T + + W P+
Sbjct: 22296 TRHT-VTLKWAKPE 22308
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P +++V D + +SW P G S + +YIV+ +EA ++W + +V
Sbjct: 19626 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV----KK 19681
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPS-GPPQDVRVEAKSSTE 185
TS V NL P Y+ R+ A N G P+ P V ++ + PP+ + V +
Sbjct: 19682 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNS 19741
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W PP RD I GY ++E
Sbjct: 19742 ATLAWLPPLRD-GGAKIDGYITSYRE 19766
Score = 60.1 bits (139), Expect = 4e-08
Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P K+I+ D + +++W P + G +PI++Y+++ +EA T V+ +
Sbjct: 15406 LPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR---TYIPVMSGENK 15462
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ---PVQVTTTEEVPSGPPQDVRVEAKSST 184
S +V++L P Y R+ A N++G E + PV + + P PP DV V ++
Sbjct: 15463 LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV-IAQDPKQPPDPPVDVEVHNPTAE 15521
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ +TW+PP D I+GY +
Sbjct: 15522 AMTITWKPPLYD-GGSKIMGYII 15543
Score = 60.1 bits (139), Expect = 4e-08
Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 7/151 (4%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVP 124
+++P P +V+ + ++ +SWT P G SPI Y ++ +E W + I
Sbjct: 16523 YRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITK 16582
Query: 125 GSVTSA--SVQNLQPATSYHLRIIAENRLGQSEPSQPV--QVTTTEEVPSGPPQDVRVEA 180
+ +V L Y R +A N G PS+P +V P GPP V+
Sbjct: 16583 VGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 16642
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQE 211
K+ + + + W+PP +D I GY V QE
Sbjct: 16643 KTKSSISLGWKPPAKD-GGSPIKGYIVEMQE 16672
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Query: 75 NIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQ 133
N+R D ++ + W P G S I NYIV+ +EA ST + V
Sbjct: 21800 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYST---ATTKCHKCTYKVT 21856
Query: 134 NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
L Y R++AEN G EP++ + E PS PP + + + + + + W P
Sbjct: 21857 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS-PPDSLNIMDITKSTVSLAWPKP 21915
Query: 194 QRDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
+ D I GY + Q S+ I + G
Sbjct: 21916 KHD-GGSKITGYVIEAQRKGSDQWTHITTVKG 21946
Score = 58.4 bits (135), Expect = 1e-07
Identities = 87/331 (26%), Positives = 118/331 (35%), Gaps = 32/331 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P I + + T+ +W P G S IINYIV+ +E W V
Sbjct: 23567 PEGPVVISGVTAEKCTL--AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANV----QT 23620
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S V L Y RI+A N+ G EP S+PV VP P+ V +
Sbjct: 23621 LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDA-PKAPEVTTVTKDS 23679
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+IV WE P D ILGY VL G +T G R R T
Sbjct: 23680 MIVVWERPASD-GGSEILGY------------VLEKRDKEGIRWTRCHKRLIGELRLRVT 23726
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVS 303
GL ++ Y V A N+ D PP + ++ SV +S
Sbjct: 23727 --GLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLS 23784
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W P G I QGY V V+ I+ + + L Y+ +CA
Sbjct: 23785 WSKPIYDGGCEI-QGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 23843
Query: 364 TAAGDGVRA---APVYCHTEEDVPSAPADIK 391
AG G A P+ + + P D++
Sbjct: 23844 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLE 23874
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P P V D +SWT P + G SPI Y ++ +E W + P +
Sbjct: 18631 PSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNK---TPIADL 18687
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEP---SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L +Y R+ AEN G S+P S P++ + P GPP + +++ KS
Sbjct: 18688 KFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK-PPGPPINPKLKDKSRET 18746
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ W P D ILGY V Q+
Sbjct: 18747 ADLVWTKPLSD-GGSPILGYVVECQK 18771
Score = 57.6 bits (133), Expect = 2e-07
Identities = 75/361 (20%), Positives = 138/361 (38%), Gaps = 39/361 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
E P+N+R+ D ++ +SW QP + G S I YIV+ ++ P+ W + + T
Sbjct: 27696 EPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNV---TET 27752
Query: 129 SASVQNLQPATSYHLRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ L + Y R+ A N +G S PS+ V T + GP D+ +E +
Sbjct: 27753 QFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYR 27812
Query: 188 VTWEPPQRDLWNGN---ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
R +G + +Y +EL +N+ V + + AS ++ + +
Sbjct: 27813 AGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYEL 27872
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L A+ + VQ + D P P G ++ ++++ + + W
Sbjct: 27873 KLRNAMGSASATIRVQ------------------ILDKPGPPGGPIEFKTVTAEKITLLW 27914
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNE---DAVTKQISGLHTTLSGLRRYTNYSVTVC 361
PP G G ++T+ V + V++ + T + + + Y V
Sbjct: 27915 RPPADDG------GAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVR 27968
Query: 362 AFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYT 418
A G G + + V P P + ++N + V W P + G + GY
Sbjct: 27969 AVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYF 28028
Query: 419 L 419
L
Sbjct: 28029 L 28029
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/121 (30%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGSV 127
P P N+ DQ ++Q+ W P G SPI+ YI++ +E ++W K +VP
Sbjct: 14219 PSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMK-LVPE-- 14275
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+ V L+ Y R+ AEN+ G S+PS+ + T ++ P D+ K E+I
Sbjct: 14276 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVI 14334
Query: 188 V 188
V
Sbjct: 14335 V 14335
Score = 56.8 bits (131), Expect = 4e-07
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP+ P ++D + ++ ++WT P G SPI Y +++KE K P +
Sbjct: 21102 VPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANK--TPIRM 21159
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEV-PSGPPQDVRVEAKSSTE 185
V L Y R++A N G +PS P + V + + P G P+ + + S T
Sbjct: 21160 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT- 21218
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
+ W P+ D + GY V ++L S S
Sbjct: 21219 --LIWTEPKYD-GGHKLTGYIVEKRDLPSKS 21246
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Query: 69 VPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEA-PESWPSTPQKVIVPG 125
VP P I ++D + ISW P G SP+INYIV+ ++ ++W V+ G
Sbjct: 18530 VPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW-----GVVSSG 18584
Query: 126 -SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSS 183
S T + +LQ Y R+ AEN++G P + P PP V +
Sbjct: 18585 SSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITE 18644
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
V+W P+ D I GYY+ +E+
Sbjct: 18645 NAATVSWTLPKSD-GGSPITGYYMERREV 18672
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 10/143 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP PK+++V D + ++SW P G I Y+++ + ++W KV
Sbjct: 16838 VPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWT----KVNPDCG 16893
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSST 184
T+ V +L Y R+ AENR G P + +Q TT + P PP +++ +
Sbjct: 16894 STTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKN 16953
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ ++W+PP+ D G+ + +Y+
Sbjct: 16954 TVHLSWKPPKND--GGSPVTHYI 16974
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/186 (25%), Positives = 81/186 (43%), Gaps = 9/186 (4%)
Query: 572 VPPQPPILA-VVDSYADSLHLQWSDQ-GDGGSPILGYVINYKREHGD-W-EELQVEAGTS 627
VPP P V A+++ ++W + DGGS I+GY + K + W +E +V
Sbjct: 29766 VPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLEC 29825
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT-V 686
+ + L G YQ A N G + P ++ + +TV+ +
Sbjct: 29826 NYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLI 29885
Query: 687 WLDSWGDGGCGILYFVIEYR---EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
W DGG ++ ++IE + E+ +W L N ++ F+V+ L+ Y+ R+
Sbjct: 29886 WSAPAYDGGSKVVGYIIERKPVSEVGDGRW-LKCNYTIVSDNFFTVTALSEGDTYEFRVL 29944
Query: 744 AHNNAG 749
A N AG
Sbjct: 29945 AKNAAG 29950
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
Query: 573 PPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVL 631
PP P +V D ++S+ ++W++ D GSPILGY + KRE +V +
Sbjct: 15829 PPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLE-KREVNSTHWSRVNKSLLNALK 15887
Query: 632 PN---LWCGTRYQLYITAFNRIGTGL---PCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
N L G Y + A N G G P D A+ + P P T +TT
Sbjct: 15888 ANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIEL 15947
Query: 686 VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
W +GG I+ + ++ + + +W + + R ++V + A Y+LR++A
Sbjct: 15948 EWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM-IKVRQYTVKEIREGADYKLRVSAV 16006
Query: 746 NNAG 749
N AG
Sbjct: 16007 NAAG 16010
Score = 54.8 bits (126), Expect = 2e-06
Identities = 75/309 (24%), Positives = 118/309 (38%), Gaps = 35/309 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
PE P + V + S +SW P G + I +YIVQ +E +W + +V V
Sbjct: 22485 PEGP--LAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEV----QV 22538
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
T V L Y R++A N+ G EP S+PV + P PP++ V +
Sbjct: 22539 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDPPKNPEVTTITKDS 22597
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W P D I+ Y V ++ +G +T+ R
Sbjct: 22598 MVVCWGHPDSD-GGSEIINYIVERRD---------KAGQRWIKCNKKTLTDL-----RYK 22642
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
+SGL + Y + A N+ D PPG + S S+ ++
Sbjct: 22643 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIA 22702
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT---TLSGLRRYTNYSVTV 360
W P G + I GY V A + +E + +GL T++GL Y + +
Sbjct: 22703 WNKPIYDGGSEI-TGYMVEIALPEE---DEWQIVTPPAGLKATSYTITGLTENQEYKIRI 22758
Query: 361 CAFTAAGDG 369
A + G G
Sbjct: 22759 YAMNSEGLG 22767
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 5/149 (3%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIV 123
L + P P V + +I + W +P + G S ++ Y ++ K+ K+++
Sbjct: 27592 LPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI 27651
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
T V + Y R+ AEN G +PS P + + PP++VR+ S
Sbjct: 27652 --RTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDA-CEPPRNVRITDISK 27708
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQEL 212
+ ++W+ P D I GY V ++L
Sbjct: 27709 NSVSLSWQQPAFD-GGSKITGYIVERRDL 27736
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGSV 127
P P N +V D ++ ++W++P Y G +P+ Y+V+ KEA + W + + G
Sbjct: 25930 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK- 25988
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQ 174
+V L+ T Y+ RI A N G EP+ P V E + PP+
Sbjct: 25989 -QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIE--PPE 26033
Score = 52.4 bits (120), Expect = 9e-06
Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWP--STPQKVIVPG 125
P P +V D ++ +SW +P Y G SPII Y+V+ K A ++W + PQ +
Sbjct: 20516 PAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL---- 20571
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V L T Y R+ A N++G S+PS
Sbjct: 20572 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 20603
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 70 PEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
P +P I+ + + + + W P G S I NYI++ +++ + W + V
Sbjct: 21003 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV----Q 21058
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSE--PSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T+ V L Y R+ AEN+ G E S+P+ +VP PP V+ + +
Sbjct: 21059 KTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS 21118
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNS 214
+ +TW P++ I GY++ F+E NS
Sbjct: 21119 -VSLTWTDPKK-TGGSPITGYHLEFKERNS 21146
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/152 (28%), Positives = 65/152 (42%), Gaps = 11/152 (7%)
Query: 67 HQVPEMPKN-IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIV 123
H +P P I+ + S + SW P G PI NY+V+ ++ + W VI
Sbjct: 22083 HDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR 22142
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENR--LGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
T+ L Y R+ A+NR +G S + +VP GPP +V A
Sbjct: 22143 ----TTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVP-GPPGTPQVTAV 22197
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELN 213
+ + ++W P D ILGY+V +E N
Sbjct: 22198 TKDSMTISWHEPLSD-GGSPILGYHVERKERN 22228
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQ 119
+ + + VP+ P + +I ++W +P + G S I YI++ +E + W
Sbjct: 29071 VAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVIS 29130
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVR 177
K P S T V L Y ++AEN G S ++ E P GPP V+
Sbjct: 29131 KR--PISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 29188
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
V S T + + W P D I+GY +
Sbjct: 29189 VTDTSKTTVSLEWSKPVFD-GGMEIIGYII 29217
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
Q P+ P ++ V + + + I+W P Y G S I+ YI++ + E W + +VP
Sbjct: 15505 QPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEH-LVP- 15562
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR--VEAKSS 183
+ + + + L+ Y R+ AEN G SEPS+ T + P +R +E K
Sbjct: 15563 -ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRG 15621
Query: 184 TEL 186
E+
Sbjct: 15622 DEI 15624
Score = 49.6 bits (113), Expect = 6e-05
Identities = 62/242 (25%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
S T V N+ S + EN G V+V T GPPQD++V+ + T
Sbjct: 22839 SYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTP----GPPQDLKVKEVTKTS 22894
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ +TW+PP D I Y V +E + +A+ S+ V
Sbjct: 22895 VTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKV-------------- 22939
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
LQ+ +Y V A N + P LPPG + ++ SV +SWE
Sbjct: 22940 -DQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERP-LPPGKITLMDVTRNSVSLSWE 22997
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P G + IL GY V + ++ A + T++GL + YS V A
Sbjct: 22998 KPEHDGGSRIL-GYIV---EMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNE 23053
Query: 366 AG 367
G
Sbjct: 23054 KG 23055
Score = 49.6 bits (113), Expect = 6e-05
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 10/171 (5%)
Query: 67 HQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVP 124
++ P P V ++ ++W +P G + I YI++ ++ W +K +
Sbjct: 25826 YKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTD 25885
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEV-PSGPPQDVRVEAKS 182
V L SY R+ AEN G EPS+P V + + P GPP + +V S
Sbjct: 25886 ---LRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 25942
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSN--STVLIASGPGGASYTV 231
+ + + W P D + GY V +E ++ +T +G G +TV
Sbjct: 25943 RSSVSLAWSKPIYD-GGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25992
Score = 49.2 bits (112), Expect = 8e-05
Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 9/106 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
VP+ P+N++ D+ + +I ++W P G S I YIV+ + W + + P +
Sbjct: 14514 VPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGE----PVA 14569
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP---VQVTTTEEVP 169
T V L+ Y R+ A NR G S+PS+P +Q T+E P
Sbjct: 14570 ETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAP 14615
Score = 49.2 bits (112), Expect = 8e-05
Identities = 98/450 (21%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ PK V ++ + W +P + G S I+ Y+++ ++ W +++I G
Sbjct: 23663 VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI--GE 23720
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQP--VQVTTTEEVPSGPPQDVRVEAKSST 184
+ V L Y R+ AEN G SEPS P Q GPP + +V + +
Sbjct: 23721 LR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 23779
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ ++W P D I GY V +++ + + P G + T VE
Sbjct: 23780 SVFLSWSKPIYD-GGCEIQGYIVEKCDVSVGEWTM-CTPPTGINKTNIEVEKL------- 23830
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L+KH Y + A N +E+ P L ++R
Sbjct: 23831 ----LEKH-EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGG 23885
Query: 305 EP---PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVC 361
P++GR V + V + + S L + RY + T+
Sbjct: 23886 SLRLFVPIKGR----PTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 23941
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
++ G ++A V D PS P ++K +++ + ++W PP +L G +
Sbjct: 23942 LENSS--GTKSAFVTVRV-LDTPSPPVNLKVTEITKDSVSITWEPP-----LLDGGSKIK 23993
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETS----RSPPRATHQFWVSASTRLGEGEATRVVTVL 477
+ I + R E T K + T H+ S + ++ F V+A G G + +
Sbjct: 23994 NYIVEKR-EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPI 24052
Query: 478 PSDSVPARITSFSRNIVTPWKENISLSCNK 507
VP + + VT + ++SLS K
Sbjct: 24053 KVAEVPQPPGKITVDDVT--RNSVSLSWTK 24080
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP+ P I V D ++ +SWT+P + G S II YIV+ + + E W + +
Sbjct: 24056 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 24115
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP 156
+T NL Y R++A N G+S+P
Sbjct: 24116 VIT-----NLTQGEEYLFRVVAVNEKGRSDP 24141
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGT--LTISMTQSADSGNYTCSVE 556
++ + C G P + +W G + S + + +D T LT++M + +DSG+YTC
Sbjct: 8625 SVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIAT 8684
Query: 557 NIHGRDEVTYTVEVKVPP 574
N+ G DE + + V+ PP
Sbjct: 8685 NMAGSDECSAPLTVREPP 8702
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 8/143 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
+P PK++ V + ++ + W +P + G S II YIV+ ++ W ++ I
Sbjct: 24745 LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITD-- 24802
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVTTTEEV-PSGPPQDVRVEAKSST 184
V L Y R+ AEN G EPS V + V GPP + + +
Sbjct: 24803 -LRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKN 24861
Query: 185 ELIVTWEPPQRDLWNGNILGYYV 207
+ + W P D ILGY V
Sbjct: 24862 SITLAWGKPIYD-GGSEILGYVV 24883
Score = 47.6 bits (108), Expect = 2e-04
Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 13/145 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIV-P 124
++P P + + S + ++W P Y G S + + V+ KE W QKV P
Sbjct: 28682 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILW----QKVNTSP 28737
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVT--TTEEVPSGPPQDVRVEAKS 182
S L Y R+ AEN G S PS P + T + P G P + V ++
Sbjct: 28738 ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET 28797
Query: 183 STELIVTWEPPQRDLWNGNILGYYV 207
T + W PP RD I+GY +
Sbjct: 28798 IT---LKWNPPLRD-GGSKIVGYSI 28818
Score = 47.2 bits (107), Expect = 3e-04
Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWP--STPQKVIVPG 125
P P V D+ +I + W P G SPI YIV+ +E W + P K+I
Sbjct: 16632 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLI--- 16688
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
+ V NL+ Y R+ A N G+SEPS TT E+P+ Q+
Sbjct: 16689 TTCECVVPNLKELRKYRFRVKAVNEAGESEPSD-----TTGEIPATDIQE 16733
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 469 EATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL 528
E RV + P + S +N+ E+++L C+ G P+P TW +ES++
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 529 RKNVSSDGTLTISMTQSA---DSGNYTCSVENIHGRDEVTYTVEVKV 572
++ + M + A DSG +TCS N G + + V+V
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPGS 126
VPE P+++ V + T+ ++W P Y G S IINY+++ + E + ++
Sbjct: 17643 VPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 17702
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T V+ L+ +Y R+ A N +GQ +PS
Sbjct: 17703 YT---VKGLKEGDTYEYRVSAVNIVGQGKPS 17730
Score = 46.8 bits (106), Expect = 4e-04
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRII 146
I W +P G SP+I Y ++ KE + K I+ T QNL+ Y R+
Sbjct: 24368 IQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHD--TQFKAQNLEEGIEYEFRVY 24425
Query: 147 AENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
AEN +G + S+ + + P G P+ + V+ E+ + W P D I G
Sbjct: 24426 AENIVGVGKASKNSECYVARDPCDPPGTPEPIMVK---RNEITLQWTKPVYD-GGSMITG 24481
Query: 205 YYVGFQEL 212
Y V ++L
Sbjct: 24482 YIVEKRDL 24489
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 6/118 (5%)
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM 519
+AS G + VTV S ++ ++ P E+ L C G P TW
Sbjct: 4644 TASNEAGSSSCSATVTVREPPSFVKKVDP--SYLMLPG-ESARLHCKLKGSPVIQVTWFK 4700
Query: 520 NGVGLE--STLRKN-VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L +T+R V+S+ L I+ + DSG+Y+C N G D + + +K PP
Sbjct: 4701 NNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 4758
Score = 45.2 bits (102), Expect = 0.001
Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 14/128 (10%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSD-SVPARITSFSRNIVTPWKENISLSCNKVGVPA 512
T+ F V +G+ T VV V SD +VP T +N + L C G
Sbjct: 6700 TYTFQVQ--NNVGKSSCTAVVDV--SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSP 6755
Query: 513 PATTW------TMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
+ W ++G ++T NV TL ++ S+D GNYTC N+ G DE
Sbjct: 6756 ISVAWFHEKTKIVSGAKYQTTFSDNVC---TLQLNSLDSSDMGNYTCVAANVAGSDECRA 6812
Query: 567 TVEVKVPP 574
+ V+ PP
Sbjct: 6813 VLTVQEPP 6820
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS---SDGTLT 539
P + + V E+I L C G P +W N L + + N+S S LT
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 7350
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I+ + DSG+Y C N G + + VK PP
Sbjct: 7351 INEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 7385
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P + TW NG+ + + R N+++ L I + D+G Y C +EN G+D +
Sbjct: 8820 GTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCS 8879
Query: 566 YTVEVKVPPQ--PPILAVVDSYADSLHLQ 592
+ + PP + V S DS LQ
Sbjct: 8880 AQILILEPPYFVKQLEPVKVSVGDSASLQ 8908
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 85 TIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T+ + W +P Y G I +YIV+ ++ P W I+ T V L +Y
Sbjct: 22299 TVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFT---VSGLTEDAAYE 22355
Query: 143 LRIIAENRLGQ-SEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
R+IA+N G S PS+P T + P V V+ K + L
Sbjct: 22356 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVIL 22400
Score = 44.4 bits (100), Expect = 0.002
Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P +P+ + I + S T+ W++P A G S I Y ++ ++ W ++ I
Sbjct: 27996 PGIPE-VTKITKNSMTVV--WSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRD--- 28049
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSSTE 185
T V L + Y R+ A N GQ S+P + + P GPP +R+ + +
Sbjct: 28050 TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSS 28109
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQE 211
+ + W P D + GY V ++
Sbjct: 28110 ITLGWSKPVYD-GGSAVTGYVVEIRQ 28134
Score = 43.2 bits (97), Expect = 0.005
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 79 IDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
ID TI + W P G S I+ Y ++ ++ E W + S +V L P
Sbjct: 28791 IDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDV---SECQYTVTGLSP 28847
Query: 138 ATSYHLRIIAENRLGQ-SEPSQP--VQVTTTEEVP 169
Y RIIA N +G S PSQ + +T E VP
Sbjct: 28848 GDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVP 28882
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 3/96 (3%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLT 539
P +SF + T +SL C G P W + L S+ + ++S ++
Sbjct: 6443 PPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIH 6502
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
I ++D G Y C +N G D TV++K PP+
Sbjct: 6503 ILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPR 6538
Score = 42.3 bits (95), Expect = 0.009
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 13/219 (5%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYT 354
+SS V W+PP G I Q Y + + + T G TT++ L
Sbjct: 19235 VSSDRCTVCWDPPEDDGGCEI-QNYILEKCETKRMVWSTYSATVLTPG--TTVTRLIEGN 19291
Query: 355 NYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y V A G G + PV T+ D P P + S+ ++ V W PP G
Sbjct: 19292 EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGG 19351
Query: 413 -VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE-- 469
+ GY L R +K + + + P +QF V A +G GE
Sbjct: 19352 KSITGYFLEKKEKHSTRWVPVNKSAIPERRM--KVQNLLPDHEYQFRVKAENEIGIGEPS 19409
Query: 470 -ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK 507
+R V P T+F +V K +I+L K
Sbjct: 19410 LPSRPVVAKDPIEPPGPPTNF--RVVDTTKHSITLGWGK 19446
Score = 41.9 bits (94), Expect = 0.012
Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%)
Query: 447 SRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCN 506
SR P ++ G E ++VL PA I +I + +L C
Sbjct: 8480 SRVEPANAGKYTCQIKNDAGMQECFATLSVLE----PATIVEKPESIKVTTGDTCTLECT 8535
Query: 507 KVGVPAPATTWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSVENIHGRDE 563
G P +T W +G L S + +S L I +DSG Y+ V+N G+D
Sbjct: 8536 VAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDS 8595
Query: 564 VTYTVEVKVPPQPP 577
T +++V PP
Sbjct: 8596 CTASLQVSDRTVPP 8609
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
+ P P ++ ++D T+ ++W +P + G S I Y+++ ++ + W V G
Sbjct: 21890 EAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI---TTVKG 21946
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVP 169
V+NL Y +++A N G+S P S+PV V +P
Sbjct: 21947 --LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP 21990
Score = 41.5 bits (93), Expect = 0.016
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGNYTCSVENI 558
+LS +G+P P W NGV L + DG +L I T+ D G YTC N
Sbjct: 3521 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3580
Query: 559 HGR 561
+G+
Sbjct: 3581 YGK 3583
Score = 41.5 bits (93), Expect = 0.016
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q+ SAS LG ++ + +L VP ++ E+ + C+ G
Sbjct: 8112 QYNCSASNPLGTASSSAKL-ILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKI 8170
Query: 516 TWTMN------GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
TW + G + TL +N + TLT+ D+G YTC NI G+D + +
Sbjct: 8171 TWAKDNREIRPGGNYKMTLVENTA---TLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLG 8227
Query: 570 VKVPPQ 575
V+ PP+
Sbjct: 8228 VQEPPR 8233
Score = 41.5 bits (93), Expect = 0.016
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
Q P +++V + I W +P++ G S II Y+V + W Q+V+ S
Sbjct: 20809 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW----QRVMKSLS 20864
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
+ S ++L Y R+ AEN G+ PS+ + V ++V + P D++
Sbjct: 20865 L-QYSAKDLTEGKEYTFRVSAENENGEGTPSE-ITVVARDDVVA-PDLDLK 20912
Score = 40.7 bits (91), Expect = 0.028
Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P+ I V + I + WT+P Y G S I YIV+ ++ P+ W ++
Sbjct: 24451 PGTPEPIMV---KRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIE--- 24504
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ-SEPSQPV-QVTTTEEV 168
T +V L Y R+IA+N G S+PS +T +EV
Sbjct: 24505 TQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEV 24547
Score = 40.3 bits (90), Expect = 0.037
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 468 GEATRVVTVLPSDS-VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
G++ V+V SD VP +++ ++ L C G + W +G + S
Sbjct: 7651 GKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVS 7710
Query: 527 TLRKNVS-SDG--TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ S S+ TL +S+ + +D+G YTC N+ G DE + + V+ PP
Sbjct: 7711 GPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 7761
Score = 39.5 bits (88), Expect = 0.065
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-----SDGTLTISMTQSADSGNYTCS 554
++ C G P P W +GV L + R VS + L ISMT + D+G YT
Sbjct: 1098 SVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIV 1157
Query: 555 VENIHG 560
V N HG
Sbjct: 1158 VRNKHG 1163
Score = 39.5 bits (88), Expect = 0.065
Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q+ S +G TVL D P T RN+ + L C G
Sbjct: 5013 QYTFEISNEVGSSSCETTFTVLDRDIAPF-FTKPLRNVDSVVNGTCRLDCKIAGSLPMRV 5071
Query: 516 TWTMNGVGLESTLRKNVSS-DGT--LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+W +G + ++ R ++ +GT L I D+GN+TC N G + + + V+
Sbjct: 5072 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 5131
Query: 573 PP 574
PP
Sbjct: 5132 PP 5133
Score = 39.5 bits (88), Expect = 0.065
Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)
Query: 456 QFWVSASTRLGEGEATRVVTVL-PSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPA 514
Q+ SAS LG ++ +T P S I S +++ E+ C+ G
Sbjct: 7171 QYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAG--ESADFECHVTGAQPMR 7228
Query: 515 TTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
TW+ + + ++ G L I DSG YTC N G+D + + VK
Sbjct: 7229 ITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 7288
Query: 572 VPPQ 575
PP+
Sbjct: 7289 EPPK 7292
Score = 39.5 bits (88), Expect = 0.065
Identities = 41/192 (21%), Positives = 77/192 (40%), Gaps = 8/192 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P G L+ ++++ ++W PP G I Y + + + V+ ++
Sbjct: 25727 DRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANI-SHYIIEKRETSRLSWTQ--VSTEV 25783
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDG--VRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
L+ ++ L Y V A G G + + PV P P+ + + +++
Sbjct: 25784 QALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKD 25843
Query: 399 KILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
++V+W P G + GY L E R +K+ L+ L + +++F
Sbjct: 25844 SMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRL--RVTGLTEGHSYEF 25901
Query: 458 WVSASTRLGEGE 469
V+A G GE
Sbjct: 25902 RVAAENAAGVGE 25913
Score = 39.1 bits (87), Expect = 0.086
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS---SDGTLT 539
PA I + + E +L C G P + W +G L S+ + S +L
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLR 6689
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP 577
I + D+G YT V+N G+ T V+V PP
Sbjct: 6690 ILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPP 6727
Score = 39.1 bits (87), Expect = 0.086
Identities = 26/126 (20%), Positives = 50/126 (39%), Gaps = 3/126 (2%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q+ A +G+ T + + P+ S + + L G
Sbjct: 9149 QYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 9208
Query: 516 TWTMNGVGLESTLRKNVS-SDGTLTISMTQSA--DSGNYTCSVENIHGRDEVTYTVEVKV 572
W N + ++ T ++ + TL + + ++ D+G YTC V N G T ++ +K
Sbjct: 9209 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 9268
Query: 573 PPQPPI 578
P +PP+
Sbjct: 9269 PKKPPV 9274
Score = 38.7 bits (86), Expect = 0.11
Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 4/110 (3%)
Query: 468 GEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST 527
G AT T+ + P I S +V ++ + C G P +W ++G + +
Sbjct: 5774 GTATSKATLFVKEP-PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAI 5832
Query: 528 LRKNVSS-DG--TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +S DG T IS + +SG Y C N G + ++VK PP
Sbjct: 5833 QKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 5882
Score = 38.7 bits (86), Expect = 0.11
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISM 542
A + S + V P K +I L G + TW +G + ++ + N V+++ T + +
Sbjct: 6914 AFLKRLSDHSVEPGK-SIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEI 6972
Query: 543 TQSA--DSGNYTCSVENIHGRDEVTYTVEVKVPP 574
S D+G Y+C +EN GRD V PP
Sbjct: 6973 LNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 7006
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G E + V+TVL PARI + +L C G P + W +G L
Sbjct: 7558 GMRECSAVLTVLE----PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELS 7613
Query: 526 STLRKNVS---SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP 577
+ + +++ +L I + +D G Y+ V+N G+ T +V V PP
Sbjct: 7614 ADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPP 7668
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 508 VGVPAPATTWTMNGVGLES----TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE 563
VG PAP TW L + T+ N + GT ++ Q DSG Y C EN+ G E
Sbjct: 3645 VGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLG--E 3702
Query: 564 VTYTVEVKV 572
T E+ V
Sbjct: 3703 STCAAELLV 3711
Score = 37.9 bits (84), Expect = 0.20
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT---ISMTQSADSGNYTCSVE 556
++ L C G P +W + L S + + S+ LT I +AD G Y C
Sbjct: 8342 DVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKAT 8401
Query: 557 NIHGRDEVTYTVEVKVPPQ 575
N G D ++ +K PP+
Sbjct: 8402 NDVGSDTCVGSIALKAPPR 8420
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSVE 556
++ L C G P TW N + S+ + ++ S L I+ +D+G Y C V
Sbjct: 5898 DVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVS 5957
Query: 557 NIHGRDEVTYTVEVKVPP 574
N G + V +K PP
Sbjct: 5958 NEGGSCSCSTRVALKEPP 5975
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGTLTISMTQ--SADSGNYTCSV 555
E + LSC+ G W G ++ + R + S + GT + + ADSG+Y C
Sbjct: 9288 EYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 9347
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N+ G D V +K P
Sbjct: 9348 SNVAGSDTTKSKVTIKDKP 9366
Score = 37.1 bits (82), Expect = 0.35
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 3/75 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTISMTQSA--DSGNYTCSVENIH 559
L+C G P TW N ++ + + +S + T + +T DSG Y C +N
Sbjct: 5246 LACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEA 5305
Query: 560 GRDEVTYTVEVKVPP 574
G D + V VK P
Sbjct: 5306 GSDHCSSIVIVKESP 5320
Score = 36.7 bits (81), Expect = 0.46
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS-SDGT--LTISMTQSADSGNYTCSVEN 557
I L C G + W + + ++ + S D T L IS + DSG YTCS N
Sbjct: 5619 IDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATN 5678
Query: 558 IHGRDEVTYTVEVKVPP 574
G ++ + + VK PP
Sbjct: 5679 KAGHNQCSGHLTVKEPP 5695
Score = 36.7 bits (81), Expect = 0.46
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
PA+I ++++ K+ ++L C G P W +G + + ++S + +
Sbjct: 6067 PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFR 6126
Query: 543 TQSA---DSGNYTCSVENIHGR---DEVTYTVEVKVPP 574
QS DSG YT VEN G D ++ +PP
Sbjct: 6127 IQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPP 6164
Score = 36.7 bits (81), Expect = 0.46
Identities = 25/122 (20%), Positives = 47/122 (38%), Gaps = 4/122 (3%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
Q+ G + VL ++P T + +I + C G +
Sbjct: 6137 QYTFKVENDFGSSSCDAYLRVL-DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISA 6195
Query: 516 TWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
W +G + ++ + + +L ++ + D+ NYTC V N+ G D + + VK
Sbjct: 6196 QWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 6255
Query: 573 PP 574
PP
Sbjct: 6256 PP 6257
Score = 36.7 bits (81), Expect = 0.46
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 3/85 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSV 555
+++SL C G P +W L T ++ TL + DSG YTC
Sbjct: 7021 DSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 7080
Query: 556 ENIHGRDEVTYTVEVKVPPQPPILA 580
EN G ++ PP A
Sbjct: 7081 ENSIGTASSKTVFRIQERQLPPSFA 7105
Score = 36.7 bits (81), Expect = 0.46
Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSV 555
E+ C+ G +W + + S + +S + LT+ DSG YTC
Sbjct: 9095 ESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYA 9154
Query: 556 ENIHGRDEVTYTVEVKVPPQPP 577
N G+D T + +K PP
Sbjct: 9155 VNEVGKDSCTAQLNIKERLIPP 9176
Score = 36.3 bits (80), Expect = 0.61
Identities = 26/110 (23%), Positives = 42/110 (38%), Gaps = 5/110 (4%)
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT 515
++ AS G T +TV +++ P S +++ T + C G P T
Sbjct: 4452 EYTCKASNEYGSVSCTATLTV--TEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIET 4509
Query: 516 TWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSVENIHGRD 562
W +G L + +S + L +S D G Y+C N G D
Sbjct: 4510 IWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGAD 4559
Score = 36.3 bits (80), Expect = 0.61
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP +++ + D ++ +SWT+P + G S I Y+V+ K + ++W
Sbjct: 28388 EVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG-----IS 28442
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE 166
V L+ + R+ A+N G S+P +T E
Sbjct: 28443 KTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE 28483
Score = 35.9 bits (79), Expect = 0.80
Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 15/151 (9%)
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSD-SVPARI 486
+E+GT ++ P+T P + ++ V A R G + ++TV + V
Sbjct: 1508 KEDGTQSLIIVPAT---------PSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMF 1558
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTIS 541
+N+ + + G P P W N + + +GT L I
Sbjct: 1559 VEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKID 1618
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
T S DS YT + N GRD V V+V
Sbjct: 1619 STVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649
Score = 35.9 bits (79), Expect = 0.80
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 508 VGVPAPATT-WTMNGVGLESTLRKNVSSDGTLT---ISMTQSADSGNYTCSVENIHGRDE 563
VG AP T W + L S ++V D T T + ++ DSG Y C + N G
Sbjct: 5718 VGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTAT 5777
Query: 564 VTYTVEVKVPPQ 575
T+ VK PPQ
Sbjct: 5778 SKATLFVKEPPQ 5789
Score = 35.9 bits (79), Expect = 0.80
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS---DGTLTISMTQSADSGNYTCSVE 556
++ L C G P W + + ++ + ++S D +L I +++D G Y C
Sbjct: 7401 DVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKAT 7460
Query: 557 NIHGRDEVTYTVEVKVPPQ 575
N G D + +V+ K PP+
Sbjct: 7461 NEVGSDTCSCSVKFKEPPR 7479
Score = 35.9 bits (79), Expect = 0.80
Identities = 27/141 (19%), Positives = 58/141 (41%), Gaps = 7/141 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP +++ + + ++W+ P G S I +I++ K+A P +
Sbjct: 16123 VPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQP----IETER 16178
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTEL 186
+ + L Y R+IA+N+ G P + + + + P P+ + ++ + +
Sbjct: 16179 SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTI 16238
Query: 187 IVTWEPPQRDLWNGNILGYYV 207
+ W+ P R I GY +
Sbjct: 16239 TLDWKEP-RSNGGSPIQGYII 16258
Score = 35.5 bits (78), Expect = 1.1
Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 14/228 (6%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
D P P G + + ++ +SV + WEPP G + + Y + + E V+ +
Sbjct: 27495 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQV-TNYILLKRETSTAVWTE--VSATV 27551
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAG--DGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ + L Y + A G D + +A V P P+ +R
Sbjct: 27552 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 27611
Query: 399 KILVSWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQF 457
I V W P S G +VGY L M + +K ++ T + + ++F
Sbjct: 27612 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI--RTTHFKVTTISAGLIYEF 27669
Query: 458 WVSASTRLGEGEATR-VVTVLPSDSVP----ARITSFSRNIVT-PWKE 499
V A G G+ + VL D+ RIT S+N V+ W++
Sbjct: 27670 RVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQ 27717
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT--LTISMTQSADSGNYTCSVE 556
E C G P P W +NG + + R V DG L I +S D+G + E
Sbjct: 1856 ETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAE 1915
Query: 557 NIHGRDEVTYTVEVK 571
N G E +E++
Sbjct: 1916 NPEGVIEHKVKLEIQ 1930
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 3/82 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSV 555
++ SL C G P +W L T + ++ TL + DSG Y C
Sbjct: 8903 DSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKA 8962
Query: 556 ENIHGRDEVTYTVEVKVPPQPP 577
EN G + + V+ PP
Sbjct: 8963 ENSVGEVSASTFLTVQEQKLPP 8984
Score = 34.7 bits (76), Expect = 1.8
Identities = 34/148 (22%), Positives = 57/148 (38%), Gaps = 10/148 (6%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T Q+ + +G T T+L P + + + ++ L C G P
Sbjct: 6324 TGQYTCHVTNDVGSDSCT---TMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEI 6380
Query: 514 ATTWTMNGVGLESTLRKNVSS-DGTLTISMTQ--SADSGNYTCSVENIHGRDEVTYTVEV 570
W N L ++ + ++ D I M + DSG++ C +N G + V V
Sbjct: 6381 RVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 6440
Query: 571 KVPPQ----PPILAVVDSYADSLHLQWS 594
K PP PPI+ + + SL + S
Sbjct: 6441 KEPPVFSSFPPIVETLKNAEVSLECELS 6468
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTLTISMTQSADSGNYTCSV 555
+ + L C TW+ +G L + + TL I + + DSG Y C+
Sbjct: 4586 KKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 4645
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G + TV V+ PP
Sbjct: 4646 SNEAGSSSCSATVTVREPP 4664
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/39 (35%), Positives = 24/39 (61%)
Query: 535 DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ +L + + +++DSG YTC V N+ G E + + VK P
Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEP 5225
Score = 34.3 bits (75), Expect = 2.4
Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE----SWPSTPQKVIVPG 125
+ P V D T+ + W+ P Y G S ++ YI++ K E W ++
Sbjct: 29867 DAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDN 29926
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLG 152
T V L +Y R++A+N G
Sbjct: 29927 FFT---VTALSEGDTYEFRVLAKNAAG 29950
Score = 33.9 bits (74), Expect = 3.2
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVS---SDGT--LTISMTQSADSGNYTCSVENIHGRDE 563
G P P +W +G + ++ V SDG LTI A+SG Y+ N G+
Sbjct: 31 GFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQAT 90
Query: 564 VTYTVEVKVPPQPP 577
T + VK PP
Sbjct: 91 STAELLVKAETAPP 104
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 508 VGVPAPATTWTMNGVGLESTLR-KNVSSDG--TLTISMTQSADSGNYTCSVENIHGRDEV 564
+G P W +G LE+ R + ++ G +L + S DSG TC N +G D
Sbjct: 1729 IGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHT 1788
Query: 565 TYTVEVK 571
+ T+ VK
Sbjct: 1789 SATLIVK 1795
Score = 33.1 bits (72), Expect = 5.6
Identities = 35/157 (22%), Positives = 60/157 (38%), Gaps = 10/157 (6%)
Query: 425 EDGREEGT---HKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
+DG+E T ++ + ++S E + T + S G+ + ++TV
Sbjct: 6199 KDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTV---KE 6255
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
P+ + R P + G P W + V L S + + +G+ +
Sbjct: 6256 PPSFLVKPGRQQAIP-DSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFL 6314
Query: 542 MTQSADS---GNYTCSVENIHGRDEVTYTVEVKVPPQ 575
S D+ G YTC V N G D T + V PP+
Sbjct: 6315 NLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPK 6351
Score = 33.1 bits (72), Expect = 5.6
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGL---ESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
++L+C G W +GV L E+ V + TL I T + SG Y+CS N
Sbjct: 7119 VTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASN 7178
Query: 558 IHGRDEVTYTVEVKVPPQPPILAV 581
G + + + P + P +
Sbjct: 7179 PLGTASSSARLTAREPKKSPFFDI 7202
>AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion
molecule protein.
Length = 1224
Score = 137 bits (331), Expect = 2e-31
Identities = 115/413 (27%), Positives = 182/413 (44%), Gaps = 32/413 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY---KEAPESWPSTPQKVIVPG 125
VP+ P+N+ + ++Q+R+++++W NS I YIV++ KE P W + V G
Sbjct: 627 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTR---VQG 683
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSST 184
T+ + L P Y R+IA N +G+S+PSQP T P PQ++RV+A
Sbjct: 684 KKTTV-ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 742
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
E+I+ WEP + NG L Y V ++ P GA V E T +
Sbjct: 743 EMIIKWEPLKSMEQNGPGLEYRVTWK-------------PQGA--PVEWEEETVTNHTLR 787
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++ +A Y V VQA N ED P P + ++S V+V+W
Sbjct: 788 VMTP-AVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTW 846
Query: 305 EPPPMRGRNGILQGYRVTY---APVTDWYGNEDAVT-KQISGLHTT--LSGLRRYTNYSV 358
P +G L+GY++ + + D + V + SG + + L ++ + +
Sbjct: 847 STVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHL 906
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
TV A+ + G G + P T E VP P +K ++ +SW P NG L GY
Sbjct: 907 TVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYL 966
Query: 419 LYMSVIEDGREEG--THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L +I D E G + +PS S S ++F++ A T G G+
Sbjct: 967 LQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1019
Score = 62.1 bits (144), Expect = 1e-08
Identities = 68/248 (27%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 516 TWTMNGVGLE--STLRKNVSSDGT-LTISMTQSADSGNYTCSVEN-IHGRDEVTYTVEVK 571
+W+ +G E T + DG LTIS D G Y CS + ++T +
Sbjct: 567 SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLD 626
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINY---KREHGDWEELQVEAGTSE 628
VP P L + + S+ L W D S I Y++ + K E G WEEL G
Sbjct: 627 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKT 686
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCD-IVHAYTKGTVPVK-PKHSQMITLNTTTVTV 686
V+ L RYQ + A N +G P H T P + P++ ++ + +
Sbjct: 687 TVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMII 746
Query: 687 -W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA--AHYQLR 741
W L S G G +EYR +PQ V + T ++ +TPA A Y ++
Sbjct: 747 KWEPLKSMEQNGPG-----LEYRVTWKPQGAPVEWE-EETVTNHTLRVMTPAVYAPYDVK 800
Query: 742 ITAHNNAG 749
+ A N G
Sbjct: 801 VQAINQLG 808
Score = 44.0 bits (99), Expect = 0.003
Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 1/116 (0%)
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM 519
S+ST +G +A + P +P + +I E + L C G+P P W
Sbjct: 234 SSSTEIGS-KANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNK 292
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
G L + TL I D GNY C+ N G + V V+ PP+
Sbjct: 293 IGGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPR 348
Score = 40.7 bits (91), Expect = 0.028
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTL 538
D P T N T + L C P +W + V R ++ +GTL
Sbjct: 436 DVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTL 495
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
I+ T D+G+Y+C VEN G+ VT ++++
Sbjct: 496 QINRTTEEDAGSYSCWVENAIGKTAVTANLDIR 528
Score = 38.3 bits (85), Expect = 0.15
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 7/205 (3%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L + ++SVR++WE N + Y V + + G + +T+
Sbjct: 626 DVPD-PPENLHLSERQNRSVRLTWEAG--ADHNSNISEYIVEFEGNKEEPGRWEELTRVQ 682
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH-TEEDVPSA-PADIKAAVSSRN 398
T + L + Y V A G + P H T P P +I+ S
Sbjct: 683 GKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 742
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
++++ W P S G ++ G + ++ TL T A +
Sbjct: 743 EMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMT--PAVYAPYDVK 800
Query: 459 VSASTRLGEGEATRVVTVLPSDSVP 483
V A +LG G + VT+ + P
Sbjct: 801 VQAINQLGSGPDPQSVTLYSGEDYP 825
Score = 34.7 bits (76), Expect = 1.8
Identities = 31/126 (24%), Positives = 49/126 (38%), Gaps = 3/126 (2%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP--STPQKVIVPGS 126
VPE P ++VI T +SW P N + Y++QY+ +++ I S
Sbjct: 931 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 990
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
S + NL T Y + A G +P + +T E G + V T
Sbjct: 991 KPSWHLSNLNATTKYKFYLRACTSQGCGKPITE-ESSTLGEGSKGIGKISGVNLTQKTHP 1049
Query: 187 IVTWEP 192
+ +EP
Sbjct: 1050 VEVFEP 1055
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-----REHGDWEELQVEAGT 626
VP QP L V+ D+ L W + GY++ Y+ E G+ ++ + +
Sbjct: 931 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 990
Query: 627 --SEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
S H L NL T+Y+ Y+ A G G P
Sbjct: 991 KPSWH-LSNLNATTKYKFYLRACTSQGCGKP 1020
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 468 GEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES- 526
G AT V+ + P R T ++ V N L C G P P W +NG +++
Sbjct: 333 GTATHDFHVIVEE--PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNH 390
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+V ++ + Q + Y C N+HG
Sbjct: 391 PFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 424
Score = 33.1 bits (72), Expect = 5.6
Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 9/146 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I + P+ E + C G P P +WT +G T + + S+ + T
Sbjct: 34 VPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFR 93
Query: 542 MTQ----SADSGNYTCSVENIHG---RDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQW 593
+ S G Y C N G +E+ + V V P+ I + D + L
Sbjct: 94 IPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP- 152
Query: 594 SDQGDGGSPILGYVINYKREHGDWEE 619
+ G P+ Y +N + EH + +E
Sbjct: 153 CNPPKGLPPLHIYWMNIELEHIEQDE 178
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 137 bits (331), Expect = 2e-31
Identities = 115/413 (27%), Positives = 182/413 (44%), Gaps = 32/413 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY---KEAPESWPSTPQKVIVPG 125
VP+ P+N+ + ++Q+R+++++W NS I YIV++ KE P W + V G
Sbjct: 613 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTR---VQG 669
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSST 184
T+ + L P Y R+IA N +G+S+PSQP T P PQ++RV+A
Sbjct: 670 KKTTV-ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 728
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
E+I+ WEP + NG L Y V ++ P GA V E T +
Sbjct: 729 EMIIKWEPLKSMEQNGPGLEYRVTWK-------------PQGA--PVEWEEETVTNHTLR 773
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++ +A Y V VQA N ED P P + ++S V+V+W
Sbjct: 774 VMTP-AVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTW 832
Query: 305 EPPPMRGRNGILQGYRVTY---APVTDWYGNEDAVT-KQISGLHTT--LSGLRRYTNYSV 358
P +G L+GY++ + + D + V + SG + + L ++ + +
Sbjct: 833 STVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHL 892
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
TV A+ + G G + P T E VP P +K ++ +SW P NG L GY
Sbjct: 893 TVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYL 952
Query: 419 LYMSVIEDGREEG--THKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
L +I D E G + +PS S S ++F++ A T G G+
Sbjct: 953 LQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1005
Score = 62.1 bits (144), Expect = 1e-08
Identities = 68/248 (27%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 516 TWTMNGVGLE--STLRKNVSSDGT-LTISMTQSADSGNYTCSVEN-IHGRDEVTYTVEVK 571
+W+ +G E T + DG LTIS D G Y CS + ++T +
Sbjct: 553 SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLD 612
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINY---KREHGDWEELQVEAGTSE 628
VP P L + + S+ L W D S I Y++ + K E G WEEL G
Sbjct: 613 VPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKT 672
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCD-IVHAYTKGTVPVK-PKHSQMITLNTTTVTV 686
V+ L RYQ + A N +G P H T P + P++ ++ + +
Sbjct: 673 TVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMII 732
Query: 687 -W--LDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA--AHYQLR 741
W L S G G +EYR +PQ V + T ++ +TPA A Y ++
Sbjct: 733 KWEPLKSMEQNGPG-----LEYRVTWKPQGAPVEWE-EETVTNHTLRVMTPAVYAPYDVK 786
Query: 742 ITAHNNAG 749
+ A N G
Sbjct: 787 VQAINQLG 794
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/89 (30%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 488 SFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
S S + +T K E + L C G+P P W G L + TL I
Sbjct: 246 SGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGKTLKIENVSYQ 305
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D GNY C+ N G + V V+ PP+
Sbjct: 306 DKGNYRCTASNFLGTATHDFHVIVEEPPR 334
Score = 40.7 bits (91), Expect = 0.028
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTL 538
D P T N T + L C P +W + V R ++ +GTL
Sbjct: 422 DVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTL 481
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
I+ T D+G+Y+C VEN G+ VT ++++
Sbjct: 482 QINRTTEEDAGSYSCWVENAIGKTAVTANLDIR 514
Score = 38.3 bits (85), Expect = 0.15
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 7/205 (3%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
DVP PP L + ++SVR++WE N + Y V + + G + +T+
Sbjct: 612 DVPD-PPENLHLSERQNRSVRLTWEAG--ADHNSNISEYIVEFEGNKEEPGRWEELTRVQ 668
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH-TEEDVPSA-PADIKAAVSSRN 398
T + L + Y V A G + P H T P P +I+ S
Sbjct: 669 GKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPK 728
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
++++ W P S G ++ G + ++ TL T A +
Sbjct: 729 EMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMT--PAVYAPYDVK 786
Query: 459 VSASTRLGEGEATRVVTVLPSDSVP 483
V A +LG G + VT+ + P
Sbjct: 787 VQAINQLGSGPDPQSVTLYSGEDYP 811
Score = 34.7 bits (76), Expect = 1.8
Identities = 31/126 (24%), Positives = 49/126 (38%), Gaps = 3/126 (2%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP--STPQKVIVPGS 126
VPE P ++VI T +SW P N + Y++QY+ +++ I S
Sbjct: 917 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 976
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
S + NL T Y + A G +P + +T E G + V T
Sbjct: 977 KPSWHLSNLNATTKYKFYLRACTSQGCGKPITE-ESSTLGEGSKGIGKISGVNLTQKTHP 1035
Query: 187 IVTWEP 192
+ +EP
Sbjct: 1036 VEVFEP 1041
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-----REHGDWEELQVEAGT 626
VP QP L V+ D+ L W + GY++ Y+ E G+ ++ + +
Sbjct: 917 VPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPS 976
Query: 627 --SEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
S H L NL T+Y+ Y+ A G G P
Sbjct: 977 KPSWH-LSNLNATTKYKFYLRACTSQGCGKP 1006
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 3/94 (3%)
Query: 468 GEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES- 526
G AT V+ + P R T ++ V N L C G P P W +NG +++
Sbjct: 319 GTATHDFHVIVEE--PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNH 376
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+V ++ + Q + Y C N+HG
Sbjct: 377 PFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 410
Score = 33.1 bits (72), Expect = 5.6
Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 9/146 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I + P+ E + C G P P +WT +G T + + S+ + T
Sbjct: 36 VPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFR 95
Query: 542 MTQ----SADSGNYTCSVENIHG---RDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQW 593
+ S G Y C N G +E+ + V V P+ I + D + L
Sbjct: 96 IPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP- 154
Query: 594 SDQGDGGSPILGYVINYKREHGDWEE 619
+ G P+ Y +N + EH + +E
Sbjct: 155 CNPPKGLPPLHIYWMNIELEHIEQDE 180
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 135 bits (326), Expect = 9e-31
Identities = 100/357 (28%), Positives = 150/357 (42%), Gaps = 22/357 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPST-PQKVIVPGSV 127
P P + V D TIQ+SW++ + +SPI Y +Q + P W + G+
Sbjct: 608 PGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNA 667
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A V L P Y R+IA N LG EPS P ++ T E PS P + + EL
Sbjct: 668 ETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGEL 727
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
IV W P R+ NG+ GY + F+ G + V GA +
Sbjct: 728 IVNWTPMSREYQNGDGFGYLLSFRR------------QGSTHWQTARVPGADAQYFVYSN 775
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ + + V +++YN R E+ P + P + +SS + V+WEP
Sbjct: 776 ESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEP 835
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCAFT 364
+ NGIL GY + Y D D V + +GL T+ +SGL T Y VTV A+
Sbjct: 836 V-QQDMNGILLGYEIRYWKAGDKEAAADRV--RTAGLDTSARVSGLHPNTKYHVTVRAYN 892
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTL 419
AG G + T + P P + S + + + W P P + GY +
Sbjct: 893 RAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 82.6 bits (195), Expect = 7e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 17/194 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
S ++++P T + ++I + NR G S V + EE P P V + SS+E+ VTW
Sbjct: 774 SNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTW 833
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
EP Q+D+ NG +LGY + + + A A+ VRT G T+ +SGL
Sbjct: 834 EPVQQDM-NGILLGYEIRYWK---------AGDKEAAADRVRTA-GLDTS---ARVSGLH 879
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPM 309
+ Y V V+AYN M+ P PPG + SS S+ + W+P P
Sbjct: 880 PNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISW-TFSSSSLSIKWDPVVPF 938
Query: 310 RGRNGILQGYRVTY 323
R + + GY++ Y
Sbjct: 939 RNESAV-TGYKMLY 951
Score = 57.6 bits (133), Expect = 2e-07
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 20/211 (9%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP--ATTWT 518
A +G+ +T +++V + + +S N+ +N++L C+ P TWT
Sbjct: 490 AENFMGKANSTGILSVRDATKITLAPSSADINL----GDNLTLQCHASHDPTMDLTFTWT 545
Query: 519 MNGVGLESTL------RKNVSSD-GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
++ ++ R NV G LTI Q G YTC + + TV V+
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVR 605
Query: 572 VPPQPPILAVVDSYAD-SLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQ-----VEA 624
PP PP VV D ++ L WS D SPI Y + + G W++++ +E
Sbjct: 606 GPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEG 665
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L Y+ + A N +GTG P
Sbjct: 666 NAETAQVLGLTPWMDYEFRVIASNILGTGEP 696
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/261 (21%), Positives = 94/261 (36%), Gaps = 16/261 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I + C P W+ L ++ R V+ DGTL I +D G YTC EN G
Sbjct: 436 ILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T + V+ + P A + + D+L LQ D + + I++
Sbjct: 496 KANSTGILSVRDATKITLAPSSADI-NLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFD 554
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
+ G + V+ + + N R+ T + +G P P
Sbjct: 555 KPGGHYRRTNVKETIGDLTILN--AQLRHGGKYTCMAQTVVDSASKEATVLVRGP-PGPP 611
Query: 672 KHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN---SVQATERVFS 728
+ + TT+ + D I + ++ R +W+ V +++
Sbjct: 612 GGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQ 671
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GLTP Y+ R+ A N G
Sbjct: 672 VLGLTPWMDYEFRVIASNILG 692
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N+ C G P P W NG L S R V + G L S DSG Y C EN H
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKH 401
Query: 560 G 560
G
Sbjct: 402 G 402
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ ++L C G P P W L +++ TL I D G Y C EN
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQW---TTAEPTLQIPSVSFEDEGTYECEAENS 311
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYAD-SLHLQW 593
GRD V + V+ P+ + + D+ AD +L+W
Sbjct: 312 KGRDTVQGRIIVQAQPE-WLKVISDTEADIGSNLRW 346
Score = 33.1 bits (72), Expect = 5.6
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGDWEELQVEAGTS----EHVLPNLWCGTRY 640
+ +++ W Q D +LGY I Y + GD E T+ + L T+Y
Sbjct: 826 SSEMNVTWEPVQQDMNGILLGYEIRYWKA-GDKEAAADRVRTAGLDTSARVSGLHPNTKY 884
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
+ + A+NR GTG +A T P +P + T +++++++ D
Sbjct: 885 HVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWD 933
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
+E + L+C P W MNG + LE R + + ++ T++ D+G Y C
Sbjct: 54 EEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLA 113
Query: 556 EN 557
N
Sbjct: 114 SN 115
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 135 bits (326), Expect = 9e-31
Identities = 100/357 (28%), Positives = 150/357 (42%), Gaps = 22/357 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPST-PQKVIVPGSV 127
P P + V D TIQ+SW++ + +SPI Y +Q + P W + G+
Sbjct: 608 PGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNA 667
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A V L P Y R+IA N LG EPS P ++ T E PS P + + EL
Sbjct: 668 ETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGEL 727
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
IV W P R+ NG+ GY + F+ G + V GA +
Sbjct: 728 IVNWTPMSREYQNGDGFGYLLSFRR------------QGSTHWQTARVPGADAQYFVYSN 775
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ + + V +++YN R E+ P + P + +SS + V+WEP
Sbjct: 776 ESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEP 835
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCAFT 364
+ NGIL GY + Y D D V + +GL T+ +SGL T Y VTV A+
Sbjct: 836 V-QQDMNGILLGYEIRYWKAGDKEAAADRV--RTAGLDTSARVSGLHPNTKYHVTVRAYN 892
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTL 419
AG G + T + P P + S + + + W P P + GY +
Sbjct: 893 RAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 82.6 bits (195), Expect = 7e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 17/194 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
S ++++P T + ++I + NR G S V + EE P P V + SS+E+ VTW
Sbjct: 774 SNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTW 833
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
EP Q+D+ NG +LGY + + + A A+ VRT G T+ +SGL
Sbjct: 834 EPVQQDM-NGILLGYEIRYWK---------AGDKEAAADRVRTA-GLDTS---ARVSGLH 879
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPM 309
+ Y V V+AYN M+ P PPG + SS S+ + W+P P
Sbjct: 880 PNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISW-TFSSSSLSIKWDPVVPF 938
Query: 310 RGRNGILQGYRVTY 323
R + + GY++ Y
Sbjct: 939 RNESAV-TGYKMLY 951
Score = 57.6 bits (133), Expect = 2e-07
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 20/211 (9%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP--ATTWT 518
A +G+ +T +++V + + +S N+ +N++L C+ P TWT
Sbjct: 490 AENFMGKANSTGILSVRDATKITLAPSSADINL----GDNLTLQCHASHDPTMDLTFTWT 545
Query: 519 MNGVGLESTL------RKNVSSD-GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
++ ++ R NV G LTI Q G YTC + + TV V+
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVR 605
Query: 572 VPPQPPILAVVDSYAD-SLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQ-----VEA 624
PP PP VV D ++ L WS D SPI Y + + G W++++ +E
Sbjct: 606 GPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEG 665
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L Y+ + A N +GTG P
Sbjct: 666 NAETAQVLGLTPWMDYEFRVIASNILGTGEP 696
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/261 (21%), Positives = 94/261 (36%), Gaps = 16/261 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I + C P W+ L ++ R V+ DGTL I +D G YTC EN G
Sbjct: 436 ILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T + V+ + P A + + D+L LQ D + + I++
Sbjct: 496 KANSTGILSVRDATKITLAPSSADI-NLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFD 554
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
+ G + V+ + + N R+ T + +G P P
Sbjct: 555 KPGGHYRRTNVKETIGDLTILN--AQLRHGGKYTCMAQTVVDSASKEATVLVRGP-PGPP 611
Query: 672 KHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN---SVQATERVFS 728
+ + TT+ + D I + ++ R +W+ V +++
Sbjct: 612 GGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQ 671
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GLTP Y+ R+ A N G
Sbjct: 672 VLGLTPWMDYEFRVIASNILG 692
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N+ C G P P W NG L S R V + G L S DSG Y C EN H
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKH 401
Query: 560 G 560
G
Sbjct: 402 G 402
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ ++L C G P P W L +++ TL I D G Y C EN
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQW---TTAEPTLQIPSVSFEDEGTYECEAENS 311
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYAD-SLHLQW 593
GRD V + V+ P+ + + D+ AD +L+W
Sbjct: 312 KGRDTVQGRIIVQAQPE-WLKVISDTEADIGSNLRW 346
Score = 33.1 bits (72), Expect = 5.6
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGDWEELQVEAGTS----EHVLPNLWCGTRY 640
+ +++ W Q D +LGY I Y + GD E T+ + L T+Y
Sbjct: 826 SSEMNVTWEPVQQDMNGILLGYEIRYWKA-GDKEAAADRVRTAGLDTSARVSGLHPNTKY 884
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
+ + A+NR GTG +A T P +P + T +++++++ D
Sbjct: 885 HVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWD 933
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
+E + L+C P W MNG + LE R + + ++ T++ D+G Y C
Sbjct: 54 EEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLA 113
Query: 556 EN 557
N
Sbjct: 114 SN 115
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 135 bits (326), Expect = 9e-31
Identities = 100/357 (28%), Positives = 150/357 (42%), Gaps = 22/357 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPST-PQKVIVPGSV 127
P P + V D TIQ+SW++ + +SPI Y +Q + P W + G+
Sbjct: 608 PGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNA 667
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A V L P Y R+IA N LG EPS P ++ T E PS P + + EL
Sbjct: 668 ETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGEL 727
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
IV W P R+ NG+ GY + F+ G + V GA +
Sbjct: 728 IVNWTPMSREYQNGDGFGYLLSFRR------------QGSTHWQTARVPGADAQYFVYSN 775
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ + + V +++YN R E+ P + P + +SS + V+WEP
Sbjct: 776 ESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEP 835
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCAFT 364
+ NGIL GY + Y D D V + +GL T+ +SGL T Y VTV A+
Sbjct: 836 V-QQDMNGILLGYEIRYWKAGDKEAAADRV--RTAGLDTSARVSGLHPNTKYHVTVRAYN 892
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTL 419
AG G + T + P P + S + + + W P P + GY +
Sbjct: 893 RAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 82.6 bits (195), Expect = 7e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 17/194 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
S ++++P T + ++I + NR G S V + EE P P V + SS+E+ VTW
Sbjct: 774 SNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTW 833
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
EP Q+D+ NG +LGY + + + A A+ VRT G T+ +SGL
Sbjct: 834 EPVQQDM-NGILLGYEIRYWK---------AGDKEAAADRVRTA-GLDTS---ARVSGLH 879
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPM 309
+ Y V V+AYN M+ P PPG + SS S+ + W+P P
Sbjct: 880 PNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISW-TFSSSSLSIKWDPVVPF 938
Query: 310 RGRNGILQGYRVTY 323
R + + GY++ Y
Sbjct: 939 RNESAV-TGYKMLY 951
Score = 57.6 bits (133), Expect = 2e-07
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 20/211 (9%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP--ATTWT 518
A +G+ +T +++V + + +S N+ +N++L C+ P TWT
Sbjct: 490 AENFMGKANSTGILSVRDATKITLAPSSADINL----GDNLTLQCHASHDPTMDLTFTWT 545
Query: 519 MNGVGLESTL------RKNVSSD-GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
++ ++ R NV G LTI Q G YTC + + TV V+
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVR 605
Query: 572 VPPQPPILAVVDSYAD-SLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQ-----VEA 624
PP PP VV D ++ L WS D SPI Y + + G W++++ +E
Sbjct: 606 GPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEG 665
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L Y+ + A N +GTG P
Sbjct: 666 NAETAQVLGLTPWMDYEFRVIASNILGTGEP 696
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/261 (21%), Positives = 94/261 (36%), Gaps = 16/261 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I + C P W+ L ++ R V+ DGTL I +D G YTC EN G
Sbjct: 436 ILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T + V+ + P A + + D+L LQ D + + I++
Sbjct: 496 KANSTGILSVRDATKITLAPSSADI-NLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFD 554
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
+ G + V+ + + N R+ T + +G P P
Sbjct: 555 KPGGHYRRTNVKETIGDLTILN--AQLRHGGKYTCMAQTVVDSASKEATVLVRGP-PGPP 611
Query: 672 KHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN---SVQATERVFS 728
+ + TT+ + D I + ++ R +W+ V +++
Sbjct: 612 GGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQ 671
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GLTP Y+ R+ A N G
Sbjct: 672 VLGLTPWMDYEFRVIASNILG 692
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N+ C G P P W NG L S R V + G L S DSG Y C EN H
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKH 401
Query: 560 G 560
G
Sbjct: 402 G 402
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ ++L C G P P W L +++ TL I D G Y C EN
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQW---TTAEPTLQIPSVSFEDEGTYECEAENS 311
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYAD-SLHLQW 593
GRD V + V+ P+ + + D+ AD +L+W
Sbjct: 312 KGRDTVQGRIIVQAQPE-WLKVISDTEADIGSNLRW 346
Score = 33.1 bits (72), Expect = 5.6
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGDWEELQVEAGTS----EHVLPNLWCGTRY 640
+ +++ W Q D +LGY I Y + GD E T+ + L T+Y
Sbjct: 826 SSEMNVTWEPVQQDMNGILLGYEIRYWKA-GDKEAAADRVRTAGLDTSARVSGLHPNTKY 884
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
+ + A+NR GTG +A T P +P + T +++++++ D
Sbjct: 885 HVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWD 933
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
+E + L+C P W MNG + LE R + + ++ T++ D+G Y C
Sbjct: 54 EEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLA 113
Query: 556 EN 557
N
Sbjct: 114 SN 115
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 135 bits (326), Expect = 9e-31
Identities = 100/357 (28%), Positives = 150/357 (42%), Gaps = 22/357 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPST-PQKVIVPGSV 127
P P + V D TIQ+SW++ + +SPI Y +Q + P W + G+
Sbjct: 608 PGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNA 667
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A V L P Y R+IA N LG EPS P ++ T E PS P + + EL
Sbjct: 668 ETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGEL 727
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
IV W P R+ NG+ GY + F+ G + V GA +
Sbjct: 728 IVNWTPMSREYQNGDGFGYLLSFRR------------QGSTHWQTARVPGADAQYFVYSN 775
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
++ + + V +++YN R E+ P + P + +SS + V+WEP
Sbjct: 776 ESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEP 835
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCAFT 364
+ NGIL GY + Y D D V + +GL T+ +SGL T Y VTV A+
Sbjct: 836 V-QQDMNGILLGYEIRYWKAGDKEAAADRV--RTAGLDTSARVSGLHPNTKYHVTVRAYN 892
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTL 419
AG G + T + P P + S + + + W P P + GY +
Sbjct: 893 RAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 82.6 bits (195), Expect = 7e-15
Identities = 60/194 (30%), Positives = 92/194 (47%), Gaps = 17/194 (8%)
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
S ++++P T + ++I + NR G S V + EE P P V + SS+E+ VTW
Sbjct: 774 SNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTW 833
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
EP Q+D+ NG +LGY + + + A A+ VRT G T+ +SGL
Sbjct: 834 EPVQQDM-NGILLGYEIRYWK---------AGDKEAAADRVRTA-GLDTS---ARVSGLH 879
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPM 309
+ Y V V+AYN M+ P PPG + SS S+ + W+P P
Sbjct: 880 PNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISW-TFSSSSLSIKWDPVVPF 938
Query: 310 RGRNGILQGYRVTY 323
R + + GY++ Y
Sbjct: 939 RNESAV-TGYKMLY 951
Score = 57.6 bits (133), Expect = 2e-07
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 20/211 (9%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP--ATTWT 518
A +G+ +T +++V + + +S N+ +N++L C+ P TWT
Sbjct: 490 AENFMGKANSTGILSVRDATKITLAPSSADINL----GDNLTLQCHASHDPTMDLTFTWT 545
Query: 519 MNGVGLESTL------RKNVSSD-GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
++ ++ R NV G LTI Q G YTC + + TV V+
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVR 605
Query: 572 VPPQPPILAVVDSYAD-SLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQ-----VEA 624
PP PP VV D ++ L WS D SPI Y + + G W++++ +E
Sbjct: 606 GPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEG 665
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L Y+ + A N +GTG P
Sbjct: 666 NAETAQVLGLTPWMDYEFRVIASNILGTGEP 696
Score = 45.2 bits (102), Expect = 0.001
Identities = 55/261 (21%), Positives = 94/261 (36%), Gaps = 16/261 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I + C P W+ L ++ R V+ DGTL I +D G YTC EN G
Sbjct: 436 ILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T + V+ + P A + + D+L LQ D + + I++
Sbjct: 496 KANSTGILSVRDATKITLAPSSADI-NLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFD 554
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
+ G + V+ + + N R+ T + +G P P
Sbjct: 555 KPGGHYRRTNVKETIGDLTILN--AQLRHGGKYTCMAQTVVDSASKEATVLVRGP-PGPP 611
Query: 672 KHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSN---SVQATERVFS 728
+ + TT+ + D I + ++ R +W+ V +++
Sbjct: 612 GGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQ 671
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GLTP Y+ R+ A N G
Sbjct: 672 VLGLTPWMDYEFRVIASNILG 692
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N+ C G P P W NG L S R V + G L S DSG Y C EN H
Sbjct: 343 NLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKH 401
Query: 560 G 560
G
Sbjct: 402 G 402
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ ++L C G P P W L +++ TL I D G Y C EN
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQW---TTAEPTLQIPSVSFEDEGTYECEAENS 311
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYAD-SLHLQW 593
GRD V + V+ P+ + + D+ AD +L+W
Sbjct: 312 KGRDTVQGRIIVQAQPE-WLKVISDTEADIGSNLRW 346
Score = 33.1 bits (72), Expect = 5.6
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 586 ADSLHLQWSD-QGDGGSPILGYVINYKREHGDWEELQVEAGTS----EHVLPNLWCGTRY 640
+ +++ W Q D +LGY I Y + GD E T+ + L T+Y
Sbjct: 826 SSEMNVTWEPVQQDMNGILLGYEIRYWKA-GDKEAAADRVRTAGLDTSARVSGLHPNTKY 884
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLD 689
+ + A+NR GTG +A T P +P + T +++++++ D
Sbjct: 885 HVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWD 933
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSV 555
+E + L+C P W MNG + LE R + + ++ T++ D+G Y C
Sbjct: 54 EEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLA 113
Query: 556 EN 557
N
Sbjct: 114 SN 115
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 132 bits (318), Expect = 9e-30
Identities = 96/349 (27%), Positives = 155/349 (44%), Gaps = 32/349 (9%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
S +P P+++ + SR +++SW P I + V + ++ PG
Sbjct: 425 SSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN-RERALNTTQPG 483
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSST 184
S+ +V NL+P Y R++A N G E SQP++V T E+ GP ++++ + S T
Sbjct: 484 SL-QLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 542
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+++TWEPP NG + GY + E+++ I G SY
Sbjct: 543 SILITWEPPAYA--NGPVQGYRLFCTEVSTGKEQNIEVD--GLSYK-------------- 584
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L GL+K Y++ AYN + DVPS PP + ++S+S++VSW
Sbjct: 585 -LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSW 643
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
PPP +NG + GY++ + T + T + + L +GL + + YS V A T
Sbjct: 644 LPPPSGTQNGFITGYKIRHRKTT---RRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMT 700
Query: 365 AAGDG------VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPP 407
G G P E VP P+ + + N I++SW PP
Sbjct: 701 VNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSWTPP 748
Score = 95.1 bits (226), Expect = 1e-18
Identities = 97/334 (29%), Positives = 139/334 (41%), Gaps = 40/334 (11%)
Query: 146 IAENRLGQSEPSQ----PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
+AEN G ++ S P + V P+DV SS + ++W PP GN
Sbjct: 401 VAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEA--KGN 458
Query: 202 ILGYYVGF-QELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
I + V F +E ++ L + PG TV L+ A Y V
Sbjct: 459 IQTFTVFFSREGDNRERALNTTQPGSLQLTV---------------GNLKPEAMYTFRVV 503
Query: 261 AYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
AYN + VP P LQ + S S+ ++WEPP NG +QG
Sbjct: 504 AYNEWGPGESSQPIKVATQPELQVPG-PVENLQAVSTSPTSILITWEPPAYA--NGPVQG 560
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
YR+ V+ G E + ++ GL L GL+++T YS+ A+ G GV +
Sbjct: 561 YRLFCTEVST--GKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVV 616
Query: 379 TEEDVPSA-PADIKAAVSSRNKILVSWLPPSS--PNGVLVGYTL-YMSVIEDGREEGTHK 434
T DVPSA P ++ V + I VSWLPP S NG + GY + + G E
Sbjct: 617 TLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME---- 672
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
L P+ L + + + + F VSA T G G
Sbjct: 673 -TLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTG 705
Score = 72.9 bits (171), Expect = 6e-12
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 13/206 (6%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV-TKQI 340
+PS P + +SS+ VR+SW PP G +Q + V ++ D E A+ T Q
Sbjct: 428 LPSAPRDVVPV-LVSSRFVRLSWRPPAEA--KGNIQTFTVFFSREGD--NRERALNTTQP 482
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED--VPSAPADIKAAVSSRN 398
L T+ L+ Y+ V A+ G G + P+ T+ + VP +++A +S
Sbjct: 483 GSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPT 542
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
IL++W PP+ NG + GY L+ + + G+E+ + LS++ +
Sbjct: 543 SILITWEPPAYANGPVQGYRLFCTEVSTGKEQN-----IEVDGLSYKLEGLKKFTEYSLR 597
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPA 484
A R G G +T +TV+ VP+
Sbjct: 598 FLAYNRYGPGVSTDDITVVTLSDVPS 623
Score = 48.8 bits (111), Expect = 1e-04
Identities = 59/291 (20%), Positives = 108/291 (37%), Gaps = 19/291 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTI 540
VP + N+ +I C G P P W NG V + S + V +
Sbjct: 329 VPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL 388
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP--PQPPILA-----VVDSYADS--LHL 591
+ +S D G Y C EN G + + + V P P +L VV S + L
Sbjct: 389 GVVKS-DEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRL 447
Query: 592 QWSDQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITAFNR 649
W + I + + + RE + E + G+ + + NL Y + A+N
Sbjct: 448 SWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNE 507
Query: 650 IGTGLPCDIVHAYTKG--TVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
G G + T+ VP ++ Q ++ + T++ + + + + + E
Sbjct: 508 WGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTE 567
Query: 708 MSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFT 758
+S + +++ + + GL Y LR A+N G ++ + T
Sbjct: 568 VSTGK----EQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDIT 614
Score = 48.4 bits (110), Expect = 1e-04
Identities = 61/286 (21%), Positives = 114/286 (39%), Gaps = 22/286 (7%)
Query: 470 ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR 529
++ V+ P D VP ++S R + W+ N + ++ G E L
Sbjct: 424 SSSVLPSAPRDVVPVLVSS--RFVRLSWRPPAEAKGN---IQTFTVFFSREGDNRERAL- 477
Query: 530 KNVSSDGTLTISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPPI------LAV 581
N + G+L +++ YT V N G E + ++V P+ + L
Sbjct: 478 -NTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQA 536
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQ 641
V + S+ + W P+ GY + + E +E +E + L L T Y
Sbjct: 537 VSTSPTSILITWEPPAYANGPVQGYRL-FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYS 595
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVP-VKPKHSQMITLNTTTVTV-WL-DSWGDGGCGI 698
L A+NR G G+ D + T VP P++ + +N+ ++ V WL G I
Sbjct: 596 LRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFI 655
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I +R+ ++ R +++ + +GL + Y +++A
Sbjct: 656 TGYKIRHRKTTR---RGEMETLEPNNLWYLFTGLEKGSQYSFQVSA 698
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 7/142 (4%)
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLP 478
+++++ D R++ L + H P +Q S LG+ + T
Sbjct: 79 IHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEAS----LGDSGSIISRTAKV 134
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL---ESTLRKNVSSD 535
+ + P R S + ++ + + L C +G P P W N L R V
Sbjct: 135 AVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS 194
Query: 536 GTLTISMTQSADSGNYTCSVEN 557
G L IS Q D G Y CS N
Sbjct: 195 GALQISRLQPGDIGIYRCSARN 216
Score = 36.3 bits (80), Expect = 0.61
Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 10/143 (6%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + SR+I++SW P +G N I Y +++++
Sbjct: 610 TDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR-- 667
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSG 171
+ + P ++ L+ + Y ++ A G PS T E +
Sbjct: 668 -RGEMETLEPNNLWYL-FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQV 725
Query: 172 PPQDVRVEAKSSTE-LIVTWEPP 193
P Q + + T +I++W PP
Sbjct: 726 PDQPSSLHVRPQTNCIIMSWTPP 748
Score = 35.9 bits (79), Expect = 0.80
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGN 550
N+V ++ L C G P P+ TW ++ +K ++ L IS DSG
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 307
Query: 551 YTCSVENIHGRDEVTYTVEVKVPP 574
YTC V + + + V VPP
Sbjct: 308 YTCVVTYKNENISASAELTVLVPP 331
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 129 bits (312), Expect = 5e-29
Identities = 107/387 (27%), Positives = 166/387 (42%), Gaps = 33/387 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P + + + IQ+SW P II Y + Y A + Q + +
Sbjct: 270 VPAQPADFQAEVESDTRIQLSWLLP--PQERIIMYELVYWAAEDE---DQQHKVTFDPTS 324
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
S ++++L+P T Y ++ A + +G + ++ T + PS PPQ V + ST + V
Sbjct: 325 SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRV 384
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
+W PP D NG I Y V ++ ++ G V+G S L G
Sbjct: 385 SWVPPPADSRNGVITQYSVAYEAVD------------GEDRGRHVVDGISREHSSWDLVG 432
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L+K Y V V+A+ EDVPS PP ++ L+S +V V W+ P
Sbjct: 433 LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPV 492
Query: 309 MRGRNGILQGYRVTYAPVTDWYGN-----EDAV-------TKQISGLHTTLSGLRRYTNY 356
++G ++GY+VTY + + +D + ++ TT+SGL T Y
Sbjct: 493 PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTY 552
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
SVTV A+T GDG R+ P T V + + A + + +L+SW P S +
Sbjct: 553 SVTVAAYTTKGDGARSKPKIVTTTGAV--FAKNFRVAAAMKTSVLLSWEVPDSYKSAVPF 610
Query: 417 YTLY--MSVIEDGREEGTHKRMLSPST 441
LY SV DG L P+T
Sbjct: 611 KILYNGQSVEVDGHSMRKLIADLQPNT 637
Score = 104 bits (249), Expect = 2e-21
Identities = 104/377 (27%), Positives = 162/377 (42%), Gaps = 40/377 (10%)
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+ SA + PA Y +R+ PS +QV T + VP+ P D + E +S T
Sbjct: 229 ATNSAGTRYSAPANLY-VRVRRVAPRFSIPPSPTIQVKTQQGVPA-QPADFQAEVESDTR 286
Query: 186 LIVTWE-PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ ++W PPQ + ++ Y+ E + + +SYT
Sbjct: 287 IQLSWLLPPQERIIMYELV-YWAAEDEDQQHKVTFDPT----SSYT-------------- 327
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
L L+ Y + A + + PS PP + C ++ S +VRVSW
Sbjct: 328 -LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSW 386
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT--LSGLRRYTNYSVTVCA 362
PPP RNG++ Y V Y V D V IS H++ L GL ++T Y V V A
Sbjct: 387 VPPPADSRNGVITQYSVAYEAV-DGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRA 445
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSW-LP-PSSPNGVLVGYTL 419
T G G ++PV T+EDVPS P ++ + + V W LP PS +G + GY +
Sbjct: 446 HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQV 505
Query: 420 YMSVIEDGREEG---THKRMLSPS------TLSHETSRS--PPRATHQFWVSASTRLGEG 468
+E+G G ML+ + + +ET+ S P T+ V+A T G+G
Sbjct: 506 TYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDG 565
Query: 469 EATRVVTVLPSDSVPAR 485
++ V + +V A+
Sbjct: 566 ARSKPKIVTTTGAVFAK 582
Score = 79.0 bits (186), Expect = 9e-14
Identities = 61/213 (28%), Positives = 92/213 (43%), Gaps = 9/213 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T++ R + P P+ + + S T+++SW P A N I Y V Y+
Sbjct: 355 TIEARTAQSTPSAP--PQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGED 412
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQ 174
+ +S + L+ T Y + + A +G S PV V T E+VPSGPP+
Sbjct: 413 RGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPR 472
Query: 175 DVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNST--VLIASGPGGASYTVR 232
V VE +ST + V W+ P +G I GY V + L + + I A R
Sbjct: 473 KVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWR 532
Query: 233 TVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
E + TT+SGL Y+V V AY ++
Sbjct: 533 PEE---SEDYETTISGLTPETTYSVTVAAYTTK 562
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 129 bits (311), Expect = 6e-29
Identities = 101/363 (27%), Positives = 161/363 (44%), Gaps = 39/363 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAG-NSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P P+++ +R I+++W P + + + Y V Y + + + PG +
Sbjct: 438 LPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERV-ENTSHPGEM 496
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSSTEL 186
++QNL PAT Y R++A+N+ G E S P++V T EV GP ++R A S T +
Sbjct: 497 -QVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
VTWE P NG I Y + + E ++ + + T+
Sbjct: 556 TVTWETPVSG--NGEIQNYKLYYMEKGTDKE-----------------QDVDVSSHSYTI 596
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL+K+ Y+ V AYN + DVPS P L +S+S+ + W+P
Sbjct: 597 NGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQP 656
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFT 364
P +NG + GY++ Y + D +SG L + GL R T Y+ V A T
Sbjct: 657 PAPATQNGQITGYKIRYRKAS---RKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALT 713
Query: 365 AAGDGVRAAPVYCHT------EEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVG 416
G G + T E VP P+ ++ V+S I+VSW PP + N V+ G
Sbjct: 714 INGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTS---IVVSWTPPENQNIVVRG 770
Query: 417 YTL 419
Y +
Sbjct: 771 YAI 773
Score = 99.1 bits (236), Expect = 8e-20
Identities = 101/421 (23%), Positives = 176/421 (41%), Gaps = 56/421 (13%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
Q+P N+R +I ++W P +GN I NY + Y E T ++ V S
Sbjct: 537 QLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEK-----GTDKEQDVDVSS 591
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
S ++ L+ T Y R++A N+ G + V V T +VPS PQ++ +E ++S ++
Sbjct: 592 HSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIM 651
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP NG I GY + +++ + S V T V G ++ +
Sbjct: 652 IHWQPPAPATQNGQITGYKIRYRKASRKSDV-----------TETLVSGTQLSQ---LIE 697
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXME---DVPSLP--PGALQCNALSSQSVRV 302
GL + Y V A E D +P P +L L + S+ V
Sbjct: 698 GLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVT-SIVV 756
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTV 360
SW PP +N +++GY + Y G+ A T ++ + T+ L ++Y +T+
Sbjct: 757 SWTPP--ENQNIVVRGYAIGYG-----IGSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 809
Query: 361 CAFTAAGDGV---RAAPVYCHTEED-------------VPS-----APADIKAAVSSRNK 399
AF G+G+ +A HT+ VP P ++A++ S +
Sbjct: 810 KAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDT 869
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
I ++W S P + + Y +V + T + + +TLS+ + P ++F
Sbjct: 870 IRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFS 929
Query: 459 V 459
V
Sbjct: 930 V 930
Score = 92.7 bits (220), Expect = 7e-18
Identities = 104/441 (23%), Positives = 173/441 (39%), Gaps = 37/441 (8%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + + S++I I W P N I Y ++Y++A S
Sbjct: 621 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKA--SR 678
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE------V 168
S + +V G+ S ++ L T Y+ R+ A G + + T E V
Sbjct: 679 KSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRV 738
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P + V T ++V+W PP+ N + GY +G+ + S I
Sbjct: 739 PE-VPSSLHVRPLV-TSIVVSWTPPENQ--NIVVRGYAIGYG-IGSPHAQTIKVDYKQRY 793
Query: 229 YTVRTVEGAG----TARSRTTLS-GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
YT+ ++ + T ++ + G+ + + S + P
Sbjct: 794 YTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTP 853
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
+PP +Q + LS ++R++W + I T W N A TK +
Sbjct: 854 MMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR----WKTNIPANTKYKNAN 909
Query: 344 HTTLS----GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
TTLS GL+ T Y +V + + T E VP++P VS K
Sbjct: 910 ATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGK 969
Query: 400 ---ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP---STLSHETSRSPPRA 453
I+V+W PPS NG + GY +Y S D E H ++ P + L+H+
Sbjct: 970 PKTIIVNWQPPSEANGKITGYIIYYST--DVNAE-IHDWVIEPVVGNRLTHQIQELTLDT 1026
Query: 454 THQFWVSASTRLGEGEATRVV 474
+ F + A G G + V
Sbjct: 1027 PYYFKIQARNSKGMGPMSEAV 1047
Score = 88.2 bits (209), Expect = 1e-16
Identities = 88/334 (26%), Positives = 136/334 (40%), Gaps = 31/334 (9%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGP----PQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
IAEN +G ++ + + +GP P+DV S+ + +TW P D +G+
Sbjct: 411 IAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDP-HGD 469
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
L Y V + + G A V G + T+ L Y V A
Sbjct: 470 NLTYSVFYTK------------EGIARERVENTSHPG--EMQVTIQNLMPATVYIFRVMA 515
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
N +V P L+ A S S+ V+WE P + G NG +Q Y+
Sbjct: 516 QNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETP-VSG-NGEIQNYK 573
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE 380
+ Y G + +S T++GL++YT YS V A+ G GV V T
Sbjct: 574 LYYMEK----GTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTL 629
Query: 381 EDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
DVPS AP ++ V + I++ W P P++ NG + GY + + R+ + ++
Sbjct: 630 SDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYR--KASRKSDVTETLV 687
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT 471
S + LS + F V+A T G G AT
Sbjct: 688 SGTQLSQLIEGLDRGTEYNFRVAALTINGTGPAT 721
Score = 68.9 bits (161), Expect = 9e-11
Identities = 92/398 (23%), Positives = 155/398 (38%), Gaps = 30/398 (7%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSS-PNGVLVGYTLYMSVIEDGREEGTHKRML 437
T +PSAP D+ A++ S I ++W P+S P+G + Y+++ + ++G +
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT--KEGIARERVENTS 491
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV--LPSDSVPARITSFSRNIVT 495
P + P + F V A + G GE++ + V P +P + +
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 496 PWKENISLSCNKVG---VPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
P ++ G + + G E + +VSS + TI+ + ++
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDV--DVSSH-SYTINGLKKYTEYSFR 608
Query: 553 CSVENIHGRDEVTYTVEVK----VP---PQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
N HG T V V+ VP PQ L V +S + +H Q I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 606 YVINYKR--EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y++ D E V ++ L GT Y + A GTG D + A T
Sbjct: 669 YKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAET 728
Query: 664 ------KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVS 717
+ VP P + L T+ V W + + I Y + P + +
Sbjct: 729 FESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQN-IVVRGYAIGYG-IGSPHAQTIK 786
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
V +R +++ L P++HY + + A NN G + LY
Sbjct: 787 --VDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLY 822
Score = 68.1 bits (159), Expect = 2e-10
Identities = 92/398 (23%), Positives = 162/398 (40%), Gaps = 39/398 (9%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS 341
+PS P + + +S++ ++++W P L Y V Y + E
Sbjct: 438 LPSAPRDVV-ASLVSTRFIKLTWRTPASDPHGDNLT-YSVFYTK--EGIARERVENTSHP 493
Query: 342 G-LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV--PSAPADIKAAVSSRN 398
G + T+ L T Y V A G G +AP+ T+ +V P +++A +S
Sbjct: 494 GEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT 553
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQF 457
I V+W P S NG + Y LY E+GT K + S+ S+ + + F
Sbjct: 554 SITVTWETPVSGNGEIQNYKLYY------MEKGTDKEQDVDVSSHSYTINGLKKYTEYSF 607
Query: 458 WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-T 516
V A + G G +T V V VP ++ +N+ + + S+ + PAPAT
Sbjct: 608 RVVAYNKHGPGVSTPDVAVRTLSDVP---SAAPQNLSLEVRNSKSIMIH-WQPPAPATQN 663
Query: 517 WTMNGVGL---ESTLRKNVSS---DGTLTISMTQSADSG---NYTCSVENIHGRDEVTYT 567
+ G + +++ + +V+ GT + + D G N+ + I+G T
Sbjct: 664 GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDW 723
Query: 568 V----------EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
+ E +VP P L V S+ + W+ + + GY I Y
Sbjct: 724 LSAETFESDLDETRVPEVPSSLH-VRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHA 782
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ ++V+ + + NL + Y + + AFN +G G+P
Sbjct: 783 QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIP 820
Score = 46.8 bits (106), Expect = 4e-04
Identities = 61/273 (22%), Positives = 100/273 (36%), Gaps = 20/273 (7%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTISMTQSADSGN 550
NI +I C G P P W NG + + S K V + + +S D G
Sbjct: 349 NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKS-DEGF 407
Query: 551 YTCSVENIHGRDE------VTYTVEVKVPPQPPI-LAVVDSYADS--LHLQW-SDQGDGG 600
Y C EN G + + P P VV S + + L W + D
Sbjct: 408 YQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH 467
Query: 601 SPILGYVINYKREHGDWEELQ--VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
L Y + Y +E E ++ G + + NL T Y + A N+ G+G
Sbjct: 468 GDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAP 527
Query: 659 VHAYTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
+ T+ V P + + + T++TV ++ G I + + Y E +
Sbjct: 528 LRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDK---- 583
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + ++++GL Y R+ A+N G
Sbjct: 584 EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVE 556
+++ L C G+P P W N L ES+ R + + G+L IS D+G Y C +
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 557 NIHGRDEVTYTVEVKVPPQPPIL 579
N G + + E+ V QP L
Sbjct: 324 N--GNETIEAQAELTVQAQPEFL 344
Score = 41.9 bits (94), Expect = 0.012
Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 20/193 (10%)
Query: 73 PKNIRVIDQQSR--TIQISWTQPYAGNSPIINYIVQYKEAPES----WPSTPQKVIVPGS 126
PK++ V+ ++ + TI ++W P N I YI+ Y + W P V G+
Sbjct: 958 PKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP----VVGN 1013
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT-----TEEVPSGPPQDVRVEAK 181
+ +Q L T Y+ +I A N G S+ VQ T ++++P+ +
Sbjct: 1014 RLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQASGSGGKGS 1073
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+L ++PP +G+ + L+SN ++I G + V + R
Sbjct: 1074 RLPDLGSDYKPPM----SGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTR 1129
Query: 242 SRTTLSGLQKHAA 254
RTT +K AA
Sbjct: 1130 -RTTSHQKKKRAA 1141
Score = 35.5 bits (78), Expect = 1.1
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 5/161 (3%)
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+++++ D R + L S + H P +Q V+ LG +R ++ +
Sbjct: 92 FLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQC-VATVESLGT-IISRTAKLIVA 149
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
+P R TS N L+C P W N L R G L
Sbjct: 150 -GLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLV 207
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA 580
IS D G Y C VE+ G + + VE+KV P P +++
Sbjct: 208 ISNATEGDGGLYRCVVES-GGPPKYSDEVELKVLPDPEVIS 247
Score = 32.3 bits (70), Expect = 9.9
Identities = 36/168 (21%), Positives = 60/168 (35%), Gaps = 18/168 (10%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
SR WK NI + A ++ + G L+ N + ++ +T+ S
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANATTLSYLVTG------LKPNTLYE--FSVMVTKGRRSS 939
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVIN 609
++ + HG T+ + PP+ + + ++ + W + I GY+I
Sbjct: 940 TWSMTA---HG---TTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIY 993
Query: 610 Y----KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
Y E DW V H + L T Y I A N G G
Sbjct: 994 YSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG 1041
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 129 bits (311), Expect = 6e-29
Identities = 101/363 (27%), Positives = 161/363 (44%), Gaps = 39/363 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAG-NSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P P+++ +R I+++W P + + + Y V Y + + + PG +
Sbjct: 438 LPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERV-ENTSHPGEM 496
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSSTEL 186
++QNL PAT Y R++A+N+ G E S P++V T EV GP ++R A S T +
Sbjct: 497 -QVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
VTWE P NG I Y + + E ++ + + T+
Sbjct: 556 TVTWETPVSG--NGEIQNYKLYYMEKGTDKE-----------------QDVDVSSHSYTI 596
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL+K+ Y+ V AYN + DVPS P L +S+S+ + W+P
Sbjct: 597 NGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQP 656
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFT 364
P +NG + GY++ Y + D +SG L + GL R T Y+ V A T
Sbjct: 657 PAPATQNGQITGYKIRYRKAS---RKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALT 713
Query: 365 AAGDGVRAAPVYCHT------EEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVG 416
G G + T E VP P+ ++ V+S I+VSW PP + N V+ G
Sbjct: 714 INGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTS---IVVSWTPPENQNIVVRG 770
Query: 417 YTL 419
Y +
Sbjct: 771 YAI 773
Score = 99.1 bits (236), Expect = 8e-20
Identities = 101/421 (23%), Positives = 176/421 (41%), Gaps = 56/421 (13%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
Q+P N+R +I ++W P +GN I NY + Y E T ++ V S
Sbjct: 537 QLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEK-----GTDKEQDVDVSS 591
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
S ++ L+ T Y R++A N+ G + V V T +VPS PQ++ +E ++S ++
Sbjct: 592 HSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIM 651
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP NG I GY + +++ + S V T V G ++ +
Sbjct: 652 IHWQPPAPATQNGQITGYKIRYRKASRKSDV-----------TETLVSGTQLSQ---LIE 697
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXME---DVPSLP--PGALQCNALSSQSVRV 302
GL + Y V A E D +P P +L L + S+ V
Sbjct: 698 GLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVT-SIVV 756
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTV 360
SW PP +N +++GY + Y G+ A T ++ + T+ L ++Y +T+
Sbjct: 757 SWTPP--ENQNIVVRGYAIGYG-----IGSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 809
Query: 361 CAFTAAGDGV---RAAPVYCHTEED-------------VPS-----APADIKAAVSSRNK 399
AF G+G+ +A HT+ VP P ++A++ S +
Sbjct: 810 KAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDT 869
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
I ++W S P + + Y +V + T + + +TLS+ + P ++F
Sbjct: 870 IRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFS 929
Query: 459 V 459
V
Sbjct: 930 V 930
Score = 92.7 bits (220), Expect = 7e-18
Identities = 104/441 (23%), Positives = 173/441 (39%), Gaps = 37/441 (8%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + + S++I I W P N I Y ++Y++A S
Sbjct: 621 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKA--SR 678
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE------V 168
S + +V G+ S ++ L T Y+ R+ A G + + T E V
Sbjct: 679 KSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRV 738
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P + V T ++V+W PP+ N + GY +G+ + S I
Sbjct: 739 PE-VPSSLHVRPLV-TSIVVSWTPPENQ--NIVVRGYAIGYG-IGSPHAQTIKVDYKQRY 793
Query: 229 YTVRTVEGAG----TARSRTTLS-GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
YT+ ++ + T ++ + G+ + + S + P
Sbjct: 794 YTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTP 853
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
+PP +Q + LS ++R++W + I T W N A TK +
Sbjct: 854 MMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR----WKTNIPANTKYKNAN 909
Query: 344 HTTLS----GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
TTLS GL+ T Y +V + + T E VP++P VS K
Sbjct: 910 ATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGK 969
Query: 400 ---ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP---STLSHETSRSPPRA 453
I+V+W PPS NG + GY +Y S D E H ++ P + L+H+
Sbjct: 970 PKTIIVNWQPPSEANGKITGYIIYYST--DVNAE-IHDWVIEPVVGNRLTHQIQELTLDT 1026
Query: 454 THQFWVSASTRLGEGEATRVV 474
+ F + A G G + V
Sbjct: 1027 PYYFKIQARNSKGMGPMSEAV 1047
Score = 88.2 bits (209), Expect = 1e-16
Identities = 88/334 (26%), Positives = 136/334 (40%), Gaps = 31/334 (9%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGP----PQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
IAEN +G ++ + + +GP P+DV S+ + +TW P D +G+
Sbjct: 411 IAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDP-HGD 469
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
L Y V + + G A V G + T+ L Y V A
Sbjct: 470 NLTYSVFYTK------------EGIARERVENTSHPG--EMQVTIQNLMPATVYIFRVMA 515
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
N +V P L+ A S S+ V+WE P + G NG +Q Y+
Sbjct: 516 QNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETP-VSG-NGEIQNYK 573
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE 380
+ Y G + +S T++GL++YT YS V A+ G GV V T
Sbjct: 574 LYYMEK----GTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTL 629
Query: 381 EDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
DVPS AP ++ V + I++ W P P++ NG + GY + + R+ + ++
Sbjct: 630 SDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYR--KASRKSDVTETLV 687
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT 471
S + LS + F V+A T G G AT
Sbjct: 688 SGTQLSQLIEGLDRGTEYNFRVAALTINGTGPAT 721
Score = 68.9 bits (161), Expect = 9e-11
Identities = 92/398 (23%), Positives = 155/398 (38%), Gaps = 30/398 (7%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSS-PNGVLVGYTLYMSVIEDGREEGTHKRML 437
T +PSAP D+ A++ S I ++W P+S P+G + Y+++ + ++G +
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT--KEGIARERVENTS 491
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV--LPSDSVPARITSFSRNIVT 495
P + P + F V A + G GE++ + V P +P + +
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 496 PWKENISLSCNKVG---VPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
P ++ G + + G E + +VSS + TI+ + ++
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDV--DVSSH-SYTINGLKKYTEYSFR 608
Query: 553 CSVENIHGRDEVTYTVEVK----VP---PQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
N HG T V V+ VP PQ L V +S + +H Q I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 606 YVINYKR--EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y++ D E V ++ L GT Y + A GTG D + A T
Sbjct: 669 YKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAET 728
Query: 664 ------KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVS 717
+ VP P + L T+ V W + + I Y + P + +
Sbjct: 729 FESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQN-IVVRGYAIGYG-IGSPHAQTIK 786
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
V +R +++ L P++HY + + A NN G + LY
Sbjct: 787 --VDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLY 822
Score = 68.1 bits (159), Expect = 2e-10
Identities = 92/398 (23%), Positives = 162/398 (40%), Gaps = 39/398 (9%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS 341
+PS P + + +S++ ++++W P L Y V Y + E
Sbjct: 438 LPSAPRDVV-ASLVSTRFIKLTWRTPASDPHGDNLT-YSVFYTK--EGIARERVENTSHP 493
Query: 342 G-LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV--PSAPADIKAAVSSRN 398
G + T+ L T Y V A G G +AP+ T+ +V P +++A +S
Sbjct: 494 GEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT 553
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQF 457
I V+W P S NG + Y LY E+GT K + S+ S+ + + F
Sbjct: 554 SITVTWETPVSGNGEIQNYKLYY------MEKGTDKEQDVDVSSHSYTINGLKKYTEYSF 607
Query: 458 WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-T 516
V A + G G +T V V VP ++ +N+ + + S+ + PAPAT
Sbjct: 608 RVVAYNKHGPGVSTPDVAVRTLSDVP---SAAPQNLSLEVRNSKSIMIH-WQPPAPATQN 663
Query: 517 WTMNGVGL---ESTLRKNVSS---DGTLTISMTQSADSG---NYTCSVENIHGRDEVTYT 567
+ G + +++ + +V+ GT + + D G N+ + I+G T
Sbjct: 664 GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDW 723
Query: 568 V----------EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
+ E +VP P L V S+ + W+ + + GY I Y
Sbjct: 724 LSAETFESDLDETRVPEVPSSLH-VRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHA 782
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ ++V+ + + NL + Y + + AFN +G G+P
Sbjct: 783 QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIP 820
Score = 46.8 bits (106), Expect = 4e-04
Identities = 61/273 (22%), Positives = 100/273 (36%), Gaps = 20/273 (7%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTISMTQSADSGN 550
NI +I C G P P W NG + + S K V + + +S D G
Sbjct: 349 NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKS-DEGF 407
Query: 551 YTCSVENIHGRDE------VTYTVEVKVPPQPPI-LAVVDSYADS--LHLQW-SDQGDGG 600
Y C EN G + + P P VV S + + L W + D
Sbjct: 408 YQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH 467
Query: 601 SPILGYVINYKREHGDWEELQ--VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
L Y + Y +E E ++ G + + NL T Y + A N+ G+G
Sbjct: 468 GDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAP 527
Query: 659 VHAYTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
+ T+ V P + + + T++TV ++ G I + + Y E +
Sbjct: 528 LRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDK---- 583
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + ++++GL Y R+ A+N G
Sbjct: 584 EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVE 556
+++ L C G+P P W N L ES+ R + + G+L IS D+G Y C +
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 557 NIHGRDEVTYTVEVKVPPQPPIL 579
N G + + E+ V QP L
Sbjct: 324 N--GNETIEAQAELTVQAQPEFL 344
Score = 41.9 bits (94), Expect = 0.012
Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 20/193 (10%)
Query: 73 PKNIRVIDQQSR--TIQISWTQPYAGNSPIINYIVQYKEAPES----WPSTPQKVIVPGS 126
PK++ V+ ++ + TI ++W P N I YI+ Y + W P V G+
Sbjct: 958 PKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP----VVGN 1013
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT-----TEEVPSGPPQDVRVEAK 181
+ +Q L T Y+ +I A N G S+ VQ T ++++P+ +
Sbjct: 1014 RLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQASGSGGKGS 1073
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+L ++PP +G+ + L+SN ++I G + V + R
Sbjct: 1074 RLPDLGSDYKPPM----SGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTR 1129
Query: 242 SRTTLSGLQKHAA 254
RTT +K AA
Sbjct: 1130 -RTTSHQKKKRAA 1141
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 1/78 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD 562
L+C P W N L R G L IS D G Y C VE+ G
Sbjct: 171 LNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVES-GGPP 229
Query: 563 EVTYTVEVKVPPQPPILA 580
+ + VE+KV P P +++
Sbjct: 230 KYSDEVELKVLPDPEVIS 247
Score = 32.3 bits (70), Expect = 9.9
Identities = 36/168 (21%), Positives = 60/168 (35%), Gaps = 18/168 (10%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
SR WK NI + A ++ + G L+ N + ++ +T+ S
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANATTLSYLVTG------LKPNTLYE--FSVMVTKGRRSS 939
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVIN 609
++ + HG T+ + PP+ + + ++ + W + I GY+I
Sbjct: 940 TWSMTA---HG---TTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIY 993
Query: 610 Y----KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
Y E DW V H + L T Y I A N G G
Sbjct: 994 YSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG 1041
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 129 bits (311), Expect = 6e-29
Identities = 101/363 (27%), Positives = 161/363 (44%), Gaps = 39/363 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAG-NSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P P+++ +R I+++W P + + + Y V Y + + + PG +
Sbjct: 438 LPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERV-ENTSHPGEM 496
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVEAKSSTEL 186
++QNL PAT Y R++A+N+ G E S P++V T EV GP ++R A S T +
Sbjct: 497 -QVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
VTWE P NG I Y + + E ++ + + T+
Sbjct: 556 TVTWETPVSG--NGEIQNYKLYYMEKGTDKE-----------------QDVDVSSHSYTI 596
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+GL+K+ Y+ V AYN + DVPS P L +S+S+ + W+P
Sbjct: 597 NGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQP 656
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFT 364
P +NG + GY++ Y + D +SG L + GL R T Y+ V A T
Sbjct: 657 PAPATQNGQITGYKIRYRKAS---RKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALT 713
Query: 365 AAGDGVRAAPVYCHT------EEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVG 416
G G + T E VP P+ ++ V+S I+VSW PP + N V+ G
Sbjct: 714 INGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTS---IVVSWTPPENQNIVVRG 770
Query: 417 YTL 419
Y +
Sbjct: 771 YAI 773
Score = 99.1 bits (236), Expect = 8e-20
Identities = 101/421 (23%), Positives = 176/421 (41%), Gaps = 56/421 (13%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
Q+P N+R +I ++W P +GN I NY + Y E T ++ V S
Sbjct: 537 QLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEK-----GTDKEQDVDVSS 591
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
S ++ L+ T Y R++A N+ G + V V T +VPS PQ++ +E ++S ++
Sbjct: 592 HSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIM 651
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ W+PP NG I GY + +++ + S V T V G ++ +
Sbjct: 652 IHWQPPAPATQNGQITGYKIRYRKASRKSDV-----------TETLVSGTQLSQ---LIE 697
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXME---DVPSLP--PGALQCNALSSQSVRV 302
GL + Y V A E D +P P +L L + S+ V
Sbjct: 698 GLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVT-SIVV 756
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTV 360
SW PP +N +++GY + Y G+ A T ++ + T+ L ++Y +T+
Sbjct: 757 SWTPP--ENQNIVVRGYAIGYG-----IGSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 809
Query: 361 CAFTAAGDGV---RAAPVYCHTEED-------------VPS-----APADIKAAVSSRNK 399
AF G+G+ +A HT+ VP P ++A++ S +
Sbjct: 810 KAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDT 869
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV-IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
I ++W S P + + Y +V + T + + +TLS+ + P ++F
Sbjct: 870 IRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFS 929
Query: 459 V 459
V
Sbjct: 930 V 930
Score = 92.7 bits (220), Expect = 7e-18
Identities = 104/441 (23%), Positives = 173/441 (39%), Gaps = 37/441 (8%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESW 114
T D+ + +LS P+N+ + + S++I I W P N I Y ++Y++A S
Sbjct: 621 TPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKA--SR 678
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE------V 168
S + +V G+ S ++ L T Y+ R+ A G + + T E V
Sbjct: 679 KSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRV 738
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
P P + V T ++V+W PP+ N + GY +G+ + S I
Sbjct: 739 PE-VPSSLHVRPLV-TSIVVSWTPPENQ--NIVVRGYAIGYG-IGSPHAQTIKVDYKQRY 793
Query: 229 YTVRTVEGAG----TARSRTTLS-GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
YT+ ++ + T ++ + G+ + + S + P
Sbjct: 794 YTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTP 853
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
+PP +Q + LS ++R++W + I T W N A TK +
Sbjct: 854 MMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR----WKTNIPANTKYKNAN 909
Query: 344 HTTLS----GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
TTLS GL+ T Y +V + + T E VP++P VS K
Sbjct: 910 ATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGK 969
Query: 400 ---ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP---STLSHETSRSPPRA 453
I+V+W PPS NG + GY +Y S D E H ++ P + L+H+
Sbjct: 970 PKTIIVNWQPPSEANGKITGYIIYYST--DVNAE-IHDWVIEPVVGNRLTHQIQELTLDT 1026
Query: 454 THQFWVSASTRLGEGEATRVV 474
+ F + A G G + V
Sbjct: 1027 PYYFKIQARNSKGMGPMSEAV 1047
Score = 88.2 bits (209), Expect = 1e-16
Identities = 88/334 (26%), Positives = 136/334 (40%), Gaps = 31/334 (9%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGP----PQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
IAEN +G ++ + + +GP P+DV S+ + +TW P D +G+
Sbjct: 411 IAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDP-HGD 469
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
L Y V + + G A V G + T+ L Y V A
Sbjct: 470 NLTYSVFYTK------------EGIARERVENTSHPG--EMQVTIQNLMPATVYIFRVMA 515
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
N +V P L+ A S S+ V+WE P + G NG +Q Y+
Sbjct: 516 QNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETP-VSG-NGEIQNYK 573
Query: 321 VTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE 380
+ Y G + +S T++GL++YT YS V A+ G GV V T
Sbjct: 574 LYYMEK----GTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTL 629
Query: 381 EDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
DVPS AP ++ V + I++ W P P++ NG + GY + + R+ + ++
Sbjct: 630 SDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYR--KASRKSDVTETLV 687
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT 471
S + LS + F V+A T G G AT
Sbjct: 688 SGTQLSQLIEGLDRGTEYNFRVAALTINGTGPAT 721
Score = 68.9 bits (161), Expect = 9e-11
Identities = 92/398 (23%), Positives = 155/398 (38%), Gaps = 30/398 (7%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSS-PNGVLVGYTLYMSVIEDGREEGTHKRML 437
T +PSAP D+ A++ S I ++W P+S P+G + Y+++ + ++G +
Sbjct: 434 TTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYT--KEGIARERVENTS 491
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV--LPSDSVPARITSFSRNIVT 495
P + P + F V A + G GE++ + V P +P + +
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 496 PWKENISLSCNKVG---VPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
P ++ G + + G E + +VSS + TI+ + ++
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDV--DVSSH-SYTINGLKKYTEYSFR 608
Query: 553 CSVENIHGRDEVTYTVEVK----VP---PQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
N HG T V V+ VP PQ L V +S + +H Q I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 606 YVINYKR--EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y++ D E V ++ L GT Y + A GTG D + A T
Sbjct: 669 YKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAET 728
Query: 664 ------KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVS 717
+ VP P + L T+ V W + + I Y + P + +
Sbjct: 729 FESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQN-IVVRGYAIGYG-IGSPHAQTIK 786
Query: 718 NSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
V +R +++ L P++HY + + A NN G + LY
Sbjct: 787 --VDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLY 822
Score = 68.1 bits (159), Expect = 2e-10
Identities = 92/398 (23%), Positives = 162/398 (40%), Gaps = 39/398 (9%)
Query: 282 VPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS 341
+PS P + + +S++ ++++W P L Y V Y + E
Sbjct: 438 LPSAPRDVV-ASLVSTRFIKLTWRTPASDPHGDNLT-YSVFYTK--EGIARERVENTSHP 493
Query: 342 G-LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV--PSAPADIKAAVSSRN 398
G + T+ L T Y V A G G +AP+ T+ +V P +++A +S
Sbjct: 494 GEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT 553
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQF 457
I V+W P S NG + Y LY E+GT K + S+ S+ + + F
Sbjct: 554 SITVTWETPVSGNGEIQNYKLYY------MEKGTDKEQDVDVSSHSYTINGLKKYTEYSF 607
Query: 458 WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-T 516
V A + G G +T V V VP ++ +N+ + + S+ + PAPAT
Sbjct: 608 RVVAYNKHGPGVSTPDVAVRTLSDVP---SAAPQNLSLEVRNSKSIMIH-WQPPAPATQN 663
Query: 517 WTMNGVGL---ESTLRKNVSS---DGTLTISMTQSADSG---NYTCSVENIHGRDEVTYT 567
+ G + +++ + +V+ GT + + D G N+ + I+G T
Sbjct: 664 GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDW 723
Query: 568 V----------EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
+ E +VP P L V S+ + W+ + + GY I Y
Sbjct: 724 LSAETFESDLDETRVPEVPSSLH-VRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHA 782
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ ++V+ + + NL + Y + + AFN +G G+P
Sbjct: 783 QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIP 820
Score = 46.8 bits (106), Expect = 4e-04
Identities = 61/273 (22%), Positives = 100/273 (36%), Gaps = 20/273 (7%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG-VGLESTLRKNVSSDGTLTISMTQSADSGN 550
NI +I C G P P W NG + + S K V + + +S D G
Sbjct: 349 NIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKS-DEGF 407
Query: 551 YTCSVENIHGRDE------VTYTVEVKVPPQPPI-LAVVDSYADS--LHLQW-SDQGDGG 600
Y C EN G + + P P VV S + + L W + D
Sbjct: 408 YQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH 467
Query: 601 SPILGYVINYKREHGDWEELQ--VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
L Y + Y +E E ++ G + + NL T Y + A N+ G+G
Sbjct: 468 GDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAP 527
Query: 659 VHAYTKGTV--PVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
+ T+ V P + + + T++TV ++ G I + + Y E +
Sbjct: 528 LRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDK---- 583
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + ++++GL Y R+ A+N G
Sbjct: 584 EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVE 556
+++ L C G+P P W N L ES+ R + + G+L IS D+G Y C +
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 557 NIHGRDEVTYTVEVKVPPQPPIL 579
N G + + E+ V QP L
Sbjct: 324 N--GNETIEAQAELTVQAQPEFL 344
Score = 41.9 bits (94), Expect = 0.012
Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 20/193 (10%)
Query: 73 PKNIRVIDQQSR--TIQISWTQPYAGNSPIINYIVQYKEAPES----WPSTPQKVIVPGS 126
PK++ V+ ++ + TI ++W P N I YI+ Y + W P V G+
Sbjct: 958 PKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP----VVGN 1013
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT-----TEEVPSGPPQDVRVEAK 181
+ +Q L T Y+ +I A N G S+ VQ T ++++P+ +
Sbjct: 1014 RLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMPNDQASGSGGKGS 1073
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+L ++PP +G+ + L+SN ++I G + V + R
Sbjct: 1074 RLPDLGSDYKPPM----SGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTR 1129
Query: 242 SRTTLSGLQKHAA 254
RTT +K AA
Sbjct: 1130 -RTTSHQKKKRAA 1141
Score = 35.5 bits (78), Expect = 1.1
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 5/161 (3%)
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+++++ D R + L S + H P +Q V+ LG +R ++ +
Sbjct: 92 FLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQC-VATVESLGT-IISRTAKLIVA 149
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
+P R TS N L+C P W N L R G L
Sbjct: 150 -GLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLV 207
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA 580
IS D G Y C VE+ G + + VE+KV P P +++
Sbjct: 208 ISNATEGDGGLYRCVVES-GGPPKYSDEVELKVLPDPEVIS 247
Score = 32.3 bits (70), Expect = 9.9
Identities = 36/168 (21%), Positives = 60/168 (35%), Gaps = 18/168 (10%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSG 549
SR WK NI + A ++ + G L+ N + ++ +T+ S
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANATTLSYLVTG------LKPNTLYE--FSVMVTKGRRSS 939
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVIN 609
++ + HG T+ + PP+ + + ++ + W + I GY+I
Sbjct: 940 TWSMTA---HG---TTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIY 993
Query: 610 Y----KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
Y E DW V H + L T Y I A N G G
Sbjct: 994 YSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMG 1041
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 122 bits (293), Expect = 9e-27
Identities = 88/338 (26%), Positives = 146/338 (43%), Gaps = 16/338 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQ-KVIVPGSV 127
P P+ + + + T Q+SW +SPI Y++Q + W + ++ G
Sbjct: 268 PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKT 327
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE-VPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R +A N +G EPS+P + TEE +P P +V S +EL
Sbjct: 328 FTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSEL 387
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
++TWE +L NG GY V F+ G + + + A +R
Sbjct: 388 VITWETVPEELQNGRGFGYVVAFRPY------------GKMIWMLTVLASADASRYVFRN 435
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ + + V V +N++ E+ P+ PP ++ +LS+ + V W
Sbjct: 436 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 495
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + R G +QGY V Y D N + + T ++ L+ Y + V A+ +A
Sbjct: 496 PLEKNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSA 554
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
G G +A V T + PS P SS +KI+++W
Sbjct: 555 GTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 592
Score = 58.8 bits (136), Expect = 1e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVI 122
S + + P +I + I++ W P N I Y V+Y E +K+
Sbjct: 467 SAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRH-EDKEENARKIR 525
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
G+ TS + NL+ + YHL + A N G S V VTT + PS PP ++ + S
Sbjct: 526 TVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSS 584
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLI 220
+++I+ W+ + + GY V ++ +ST +I
Sbjct: 585 DSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVI 622
Score = 51.6 bits (118), Expect = 2e-05
Identities = 59/229 (25%), Positives = 88/229 (38%), Gaps = 14/229 (6%)
Query: 534 SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYAD-SLHLQ 592
S G L I Q +G Y C V+ R + V+ PP PP +D D + L
Sbjct: 228 SAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLS 287
Query: 593 WSDQGDGGSPILGYVINYKREHG-DWEELQ-----VEAGTSEHVLPNLWCGTRYQLYITA 646
W D SPI YVI + W+ + ++ T + L Y+ A
Sbjct: 288 WRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVA 347
Query: 647 FNRIGTGLPC-DIVHAYTKGTVP-VKPKH-SQMITLNTTTVTVW--LDSWGDGGCGILYF 701
N IG G P T+ +P V P + S + V W + G G Y
Sbjct: 348 ANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGY- 406
Query: 702 VIEYREMSQPQWRL-VSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V+ +R + W L V S A+ VF + P + +++++ NN G
Sbjct: 407 VVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKG 455
Score = 49.6 bits (113), Expect = 6e-05
Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 23/264 (8%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P TW L+ R +S DG L I +D+G+YTC N G
Sbjct: 97 VVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFG 156
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
T + VK P + PP V + +S+ L D I+ G++I++
Sbjct: 157 TASSTGNLVVKDPTRVMVPPSSMDV-TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD 215
Query: 612 REHGDWEELQVEAGTSEHVLPNL---WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
R+ GD E + ++ N+ G + T+ +R+ D++ +G P
Sbjct: 216 RD-GDHFERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAA--ADLI---VRGP-P 268
Query: 669 VKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF 727
P+ + + TT + D I +VI+ R W+ VS + + + F
Sbjct: 269 GPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTF 328
Query: 728 --SVSGLTPAAHYQLRITAHNNAG 749
+V GL P Y+ R A N G
Sbjct: 329 TATVVGLNPWVEYEFRTVAANVIG 352
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
+EN+ C G P P W NG L + R + GTL I++ +D+G Y C EN
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ-GTLNITIVNLSDAGMYQCLAEN 60
Query: 558 IHG 560
HG
Sbjct: 61 KHG 63
Score = 45.2 bits (102), Expect = 0.001
Identities = 58/264 (21%), Positives = 96/264 (36%), Gaps = 11/264 (4%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
E +P + P + S + ++WE P +NG GY V + P +
Sbjct: 367 EALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASA 426
Query: 340 ISGLHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSR 397
+ + + + ++ + V V F G+G + ++ E+ P+ PA I A S
Sbjct: 427 DASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA 486
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
I V W P N G + GY + ED +EE K + S + + +
Sbjct: 487 TDIEVFWASPLEKNRGRIQGYEVKYWRHED-KEENARKIRTVGNQTSTKITNLKGSVLYH 545
Query: 457 FWVSASTRLGEGEATRVVTVL----PSDSVPARI--TSFSRNIVTPWKENISLSCNKVGV 510
V A G G ++ V V P P I S I+ W + +L N+ V
Sbjct: 546 LAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD-NESEV 604
Query: 511 PAPATTWTMNGVGLESTLRKNVSS 534
+ N S + N +S
Sbjct: 605 KGYKVLYRWNRQSSTSVIETNKTS 628
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 7/143 (4%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP A+ + ++ + ++SW P P + I P + + V + I G
Sbjct: 267 PPGPPEAVTIDEITDTTAQLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELIDG 325
Query: 343 --LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP-VYCHTEEDVPS-APADIKAAVSSRN 398
T+ GL + Y A G G + P TEE +P PA++ S++
Sbjct: 326 KTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKS 385
Query: 399 KILVSW--LPPSSPNGVLVGYTL 419
+++++W +P NG GY +
Sbjct: 386 ELVITWETVPEELQNGRGFGYVV 408
Score = 33.5 bits (73), Expect = 4.3
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 564 VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWSDQGDGG-SPILGYVINYKREHGDWEE-- 619
V Y+ E + P +PP S A + + W+ + I GY + Y R H D EE
Sbjct: 464 VVYSAEEE-PTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR-HEDKEENA 521
Query: 620 --LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
++ + + NL Y L + A+N GTG V+ T+ P +P
Sbjct: 522 RKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQP 575
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 122 bits (293), Expect = 9e-27
Identities = 88/338 (26%), Positives = 146/338 (43%), Gaps = 16/338 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQ-KVIVPGSV 127
P P+ + + + T Q+SW +SPI Y++Q + W + ++ G
Sbjct: 597 PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKT 656
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE-VPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R +A N +G EPS+P + TEE +P P +V S +EL
Sbjct: 657 FTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSEL 716
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
++TWE +L NG GY V F+ G + + + A +R
Sbjct: 717 VITWETVPEELQNGRGFGYVVAFRPY------------GKMIWMLTVLASADASRYVFRN 764
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ + + V V +N++ E+ P+ PP ++ +LS+ + V W
Sbjct: 765 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 824
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + R G +QGY V Y D N + + T ++ L+ Y + V A+ +A
Sbjct: 825 PLEKNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSA 883
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
G G +A V T + PS P SS +KI+++W
Sbjct: 884 GTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 921
Score = 58.8 bits (136), Expect = 1e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVI 122
S + + P +I + I++ W P N I Y V+Y E +K+
Sbjct: 796 SAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRH-EDKEENARKIR 854
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
G+ TS + NL+ + YHL + A N G S V VTT + PS PP ++ + S
Sbjct: 855 TVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSS 913
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLI 220
+++I+ W+ + + GY V ++ +ST +I
Sbjct: 914 DSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVI 951
Score = 52.8 bits (121), Expect = 7e-06
Identities = 62/264 (23%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P TW L+ R +S DG L I +D+G+YTC N G
Sbjct: 425 VVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFG 484
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
T + VK P + PP V + +S+ L D I+ G++I++
Sbjct: 485 TASSTGNLVVKDPTRVMVPPSSMDV-TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD 543
Query: 612 REHGDWEELQVEAGTSEHVLPNL---WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
R+ +E + + + ++ N+ G + T+ +R+ D++ +G P
Sbjct: 544 RDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAA--ADLI---VRGP-P 597
Query: 669 VKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF 727
P+ + + TT + D I +VI+ R W+ VS + + + F
Sbjct: 598 GPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTF 657
Query: 728 --SVSGLTPAAHYQLRITAHNNAG 749
+V GL P Y+ R A N G
Sbjct: 658 TATVVGLNPWVEYEFRTVAANVIG 681
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
+EN+ C G P P W NG L + R + GTL I++ +D+G Y C EN
Sbjct: 330 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ-GTLNITIVNLSDAGMYQCLAEN 388
Query: 558 IHG 560
HG
Sbjct: 389 KHG 391
Score = 45.2 bits (102), Expect = 0.001
Identities = 58/264 (21%), Positives = 96/264 (36%), Gaps = 11/264 (4%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
E +P + P + S + ++WE P +NG GY V + P +
Sbjct: 696 EALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASA 755
Query: 340 ISGLHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSR 397
+ + + + ++ + V V F G+G + ++ E+ P+ PA I A S
Sbjct: 756 DASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA 815
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
I V W P N G + GY + ED +EE K + S + + +
Sbjct: 816 TDIEVFWASPLEKNRGRIQGYEVKYWRHED-KEENARKIRTVGNQTSTKITNLKGSVLYH 874
Query: 457 FWVSASTRLGEGEATRVVTVL----PSDSVPARI--TSFSRNIVTPWKENISLSCNKVGV 510
V A G G ++ V V P P I S I+ W + +L N+ V
Sbjct: 875 LAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD-NESEV 933
Query: 511 PAPATTWTMNGVGLESTLRKNVSS 534
+ N S + N +S
Sbjct: 934 KGYKVLYRWNRQSSTSVIETNKTS 957
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 7/143 (4%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP A+ + ++ + ++SW P P + I P + + V + I G
Sbjct: 596 PPGPPEAVTIDEITDTTAQLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELIDG 654
Query: 343 --LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP-VYCHTEEDVPS-APADIKAAVSSRN 398
T+ GL + Y A G G + P TEE +P PA++ S++
Sbjct: 655 KTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKS 714
Query: 399 KILVSW--LPPSSPNGVLVGYTL 419
+++++W +P NG GY +
Sbjct: 715 ELVITWETVPEELQNGRGFGYVV 737
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTM-NGVGLESTLRKNVSSDGTLTISMTQSAD 547
F + T + L C +G P P W +G + R++ S+G L I Q D
Sbjct: 231 FPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-KSNGILEIPNFQQED 289
Query: 548 SGNYTCSVENIHGRD 562
+G Y C EN G++
Sbjct: 290 AGLYECVAENSRGKN 304
Score = 37.1 bits (82), Expect = 0.35
Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTL--RKNVSSDGTLTISMTQSADSGNYTCSV 555
++ + L+C G P P W +NG +++ + R +V L + ++ D+G Y C+
Sbjct: 43 EKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTA 102
Query: 556 ENIHG 560
N G
Sbjct: 103 TNSFG 107
Score = 33.5 bits (73), Expect = 4.3
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 564 VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWSDQGDGG-SPILGYVINYKREHGDWEE-- 619
V Y+ E + P +PP S A + + W+ + I GY + Y R H D EE
Sbjct: 793 VVYSAEEE-PTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR-HEDKEENA 850
Query: 620 --LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
++ + + NL Y L + A+N GTG V+ T+ P +P
Sbjct: 851 RKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQP 904
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 122 bits (293), Expect = 9e-27
Identities = 88/338 (26%), Positives = 146/338 (43%), Gaps = 16/338 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQ-KVIVPGSV 127
P P+ + + + T Q+SW +SPI Y++Q + W + ++ G
Sbjct: 597 PGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKT 656
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE-VPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R +A N +G EPS+P + TEE +P P +V S +EL
Sbjct: 657 FTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSEL 716
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
++TWE +L NG GY V F+ G + + + A +R
Sbjct: 717 VITWETVPEELQNGRGFGYVVAFRPY------------GKMIWMLTVLASADASRYVFRN 764
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ + + V V +N++ E+ P+ PP ++ +LS+ + V W
Sbjct: 765 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 824
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + R G +QGY V Y D N + + T ++ L+ Y + V A+ +A
Sbjct: 825 PLEKNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSA 883
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
G G +A V T + PS P SS +KI+++W
Sbjct: 884 GTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 921
Score = 58.8 bits (136), Expect = 1e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVI 122
S + + P +I + I++ W P N I Y V+Y E +K+
Sbjct: 796 SAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRH-EDKEENARKIR 854
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
G+ TS + NL+ + YHL + A N G S V VTT + PS PP ++ + S
Sbjct: 855 TVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSS 913
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLI 220
+++I+ W+ + + GY V ++ +ST +I
Sbjct: 914 DSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVI 951
Score = 52.8 bits (121), Expect = 7e-06
Identities = 62/264 (23%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P TW L+ R +S DG L I +D+G+YTC N G
Sbjct: 425 VVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFG 484
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
T + VK P + PP V + +S+ L D I+ G++I++
Sbjct: 485 TASSTGNLVVKDPTRVMVPPSSMDV-TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFD 543
Query: 612 REHGDWEELQVEAGTSEHVLPNL---WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
R+ +E + + + ++ N+ G + T+ +R+ D++ +G P
Sbjct: 544 RDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAA--ADLI---VRGP-P 597
Query: 669 VKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF 727
P+ + + TT + D I +VI+ R W+ VS + + + F
Sbjct: 598 GPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTF 657
Query: 728 --SVSGLTPAAHYQLRITAHNNAG 749
+V GL P Y+ R A N G
Sbjct: 658 TATVVGLNPWVEYEFRTVAANVIG 681
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
+EN+ C G P P W NG L + R + GTL I++ +D+G Y C EN
Sbjct: 330 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ-GTLNITIVNLSDAGMYQCLAEN 388
Query: 558 IHG 560
HG
Sbjct: 389 KHG 391
Score = 45.2 bits (102), Expect = 0.001
Identities = 58/264 (21%), Positives = 96/264 (36%), Gaps = 11/264 (4%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
E +P + P + S + ++WE P +NG GY V + P +
Sbjct: 696 EALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASA 755
Query: 340 ISGLHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSR 397
+ + + + ++ + V V F G+G + ++ E+ P+ PA I A S
Sbjct: 756 DASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA 815
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
I V W P N G + GY + ED +EE K + S + + +
Sbjct: 816 TDIEVFWASPLEKNRGRIQGYEVKYWRHED-KEENARKIRTVGNQTSTKITNLKGSVLYH 874
Query: 457 FWVSASTRLGEGEATRVVTVL----PSDSVPARI--TSFSRNIVTPWKENISLSCNKVGV 510
V A G G ++ V V P P I S I+ W + +L N+ V
Sbjct: 875 LAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD-NESEV 933
Query: 511 PAPATTWTMNGVGLESTLRKNVSS 534
+ N S + N +S
Sbjct: 934 KGYKVLYRWNRQSSTSVIETNKTS 957
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 7/143 (4%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP A+ + ++ + ++SW P P + I P + + V + I G
Sbjct: 596 PPGPPEAVTIDEITDTTAQLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELIDG 654
Query: 343 --LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP-VYCHTEEDVPS-APADIKAAVSSRN 398
T+ GL + Y A G G + P TEE +P PA++ S++
Sbjct: 655 KTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKS 714
Query: 399 KILVSW--LPPSSPNGVLVGYTL 419
+++++W +P NG GY +
Sbjct: 715 ELVITWETVPEELQNGRGFGYVV 737
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTM-NGVGLESTLRKNVSSDGTLTISMTQSAD 547
F + T + L C +G P P W +G + R++ S+G L I Q D
Sbjct: 231 FPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-KSNGILEIPNFQQED 289
Query: 548 SGNYTCSVENIHGRD 562
+G Y C EN G++
Sbjct: 290 AGLYECVAENSRGKN 304
Score = 37.1 bits (82), Expect = 0.35
Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTL--RKNVSSDGTLTISMTQSADSGNYTCSV 555
++ + L+C G P P W +NG +++ + R +V L + ++ D+G Y C+
Sbjct: 43 EKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTA 102
Query: 556 ENIHG 560
N G
Sbjct: 103 TNSFG 107
Score = 33.5 bits (73), Expect = 4.3
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 564 VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWSDQGDGG-SPILGYVINYKREHGDWEE-- 619
V Y+ E + P +PP S A + + W+ + I GY + Y R H D EE
Sbjct: 793 VVYSAEEE-PTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR-HEDKEENA 850
Query: 620 --LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
++ + + NL Y L + A+N GTG V+ T+ P +P
Sbjct: 851 RKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQP 904
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 121 bits (292), Expect = 1e-26
Identities = 95/341 (27%), Positives = 152/341 (44%), Gaps = 21/341 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQ-KVIVPGSV 127
P P++++V D S T Q+SW NSPI + +Q + W + I+ G
Sbjct: 598 PGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKT 657
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE-EVPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R++A N +G EPS+P ++ T+ VP P ++ S +EL
Sbjct: 658 YNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSEL 717
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
++TWE +L NG GY + F+ + S + + V +VE + ++
Sbjct: 718 VITWESIPEELQNGEGFGYIIMFRPVGSTT---------WSKEKVSSVESSRFVYRNESI 768
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
L + + V V YN+ ED P L P + S+ + VSW
Sbjct: 769 IPL---SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNA 825
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK-QISGLHTT--LSGLRRYTNYSVTVCAF 363
G + GY V Y TD E + K ++SG TT ++GL+ T Y +V A+
Sbjct: 826 IAWNRNTGRVLGYEVLY--WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAY 882
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
AG G + PV T++ PS P A + +K+ ++W
Sbjct: 883 NTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNW 923
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/161 (24%), Positives = 75/161 (46%), Gaps = 4/161 (2%)
Query: 73 PKNIRVIDQQSRTIQISWTQ-PYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P+ + + +++SW + N+ ++ Y V Y +S S K+ V G+VT+
Sbjct: 806 PRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYW-TDDSKESMIGKIRVSGNVTTK 864
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L+ T Y + A N G S PV VTT + PS PP ++ + +S +L + W
Sbjct: 865 NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNS-KLCLNW 923
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
E + +LGY + +++ + T ++ + A V
Sbjct: 924 EHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLV 964
Score = 50.8 bits (116), Expect = 3e-05
Identities = 84/371 (22%), Positives = 136/371 (36%), Gaps = 26/371 (7%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PP +Q +SS + ++SW P N +Q + + T P + + V + ++
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGP--DNNSPIQIFTIQTRTPFSVGWQAVATVPEILN 654
Query: 342 G--LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP-VYCHTEEDVP-SAPADIKAAVSSR 397
G + T+ GL + Y V A + G G + P T+ VP AP +I SR
Sbjct: 655 GKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSR 714
Query: 398 NKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
++++++W +P NG GY + + + S + P +
Sbjct: 715 SELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPF 774
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVP------ARITSFSRNIVTPWKENISLSCNKVG 509
+ V GEG + V V + P + SFS + + I+ + N
Sbjct: 775 EVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGR 834
Query: 510 VPA-PATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVE--NIHG----RD 562
V WT + ES + K S T ++T + Y SV N G
Sbjct: 835 VLGYEVLYWTDD--SKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSP 892
Query: 563 EVTYTVEVKVPPQPPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKREHGDWEEL 620
V T + P QPP L L W + S +LGY I Y++ +
Sbjct: 893 PVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHI 952
Query: 621 QVEAGTSEHVL 631
TS +L
Sbjct: 953 LETNNTSAELL 963
Score = 49.2 bits (112), Expect = 8e-05
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 16/230 (6%)
Query: 534 SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQ 592
S G L I Q SG Y C+V+ + V+ PP PP + V D + + L
Sbjct: 558 SVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLS 617
Query: 593 WSDQGDGGSPILGYVINYKREHG-DWEELQ-----VEAGTSEHVLPNLWCGTRYQLYITA 646
W D SPI + I + W+ + + T + L Y+ + A
Sbjct: 618 WRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVA 677
Query: 647 FNRIGTGLPCDIVHAY-TKGTVPVKPK---HSQMITLNTTTVTVW--LDSWGDGGCGILY 700
N IG G P + TK +VPV H + + +T W + G G Y
Sbjct: 678 GNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT-WESIPEELQNGEGFGY 736
Query: 701 FVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+I +R + W + +SV+++ V+ + P + +++++ +NN G
Sbjct: 737 -IIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEG 785
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
+N+ C G P P TW NG L R + + GTL I+M +DSG Y C+ EN
Sbjct: 333 DNLLWECKASGKPNPWYTWLKNGERLNPEERIQIEN-GTLIITMLNVSDSGVYQCAAEN 390
Score = 44.0 bits (99), Expect = 0.003
Identities = 60/263 (22%), Positives = 108/263 (41%), Gaps = 19/263 (7%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+I + C P A +W L + R + DG+L I +D+G+YTC N
Sbjct: 426 DIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQF 485
Query: 560 GRDEVTYTVEVK---VPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINY 610
G + T ++ VK V PP V + +S+ L D ++ G VI+
Sbjct: 486 GTAKNTGSLIVKERTVITVPPSKMDV-TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDL 544
Query: 611 KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI-GTGLPCDIVHAYTKGTVPV 669
K+ +E + E+ + ++ N+ + T + DI+ +G P
Sbjct: 545 KKGVAHFERIGGES-VGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADII---VRGP-PG 599
Query: 670 KPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF- 727
P+ Q+ +++TT + + D I F I+ R W+ V+ + + +
Sbjct: 600 PPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYN 659
Query: 728 -SVSGLTPAAHYQLRITAHNNAG 749
+V GL+P Y+ R+ A N+ G
Sbjct: 660 ATVVGLSPWVEYEFRVVAGNSIG 682
Score = 39.1 bits (87), Expect = 0.086
Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 4/140 (2%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLTISMTQSAD 547
F I ++ L C +G P P +W ++G L ++ + S L I Q D
Sbjct: 233 FPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYS-KSQAILEIPNFQQED 291
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG-GSPILGY 606
G Y C N+ GR+ + PP+ + +L W + G +P +
Sbjct: 292 EGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTW 351
Query: 607 VINYKREHGDWEELQVEAGT 626
+ N +R + + E +Q+E GT
Sbjct: 352 LKNGERLNPE-ERIQIENGT 370
Score = 37.1 bits (82), Expect = 0.35
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTISMTQS-ADSGNYTCSV 555
K + L+C G P+P W NG ++ T+ + D G+L I+ + D G Y C
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
Query: 556 ENIHG 560
N+ G
Sbjct: 103 TNLLG 107
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 121 bits (292), Expect = 1e-26
Identities = 95/341 (27%), Positives = 152/341 (44%), Gaps = 21/341 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTPQ-KVIVPGSV 127
P P++++V D S T Q+SW NSPI + +Q + W + I+ G
Sbjct: 598 PGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKT 657
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE-EVPSGPPQDVRVEAKSSTEL 186
+A+V L P Y R++A N +G EPS+P ++ T+ VP P ++ S +EL
Sbjct: 658 YNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSEL 717
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
++TWE +L NG GY + F+ + S + + V +VE + ++
Sbjct: 718 VITWESIPEELQNGEGFGYIIMFRPVGSTT---------WSKEKVSSVESSRFVYRNESI 768
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
L + + V V YN+ ED P L P + S+ + VSW
Sbjct: 769 IPL---SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNA 825
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK-QISGLHTT--LSGLRRYTNYSVTVCAF 363
G + GY V Y TD E + K ++SG TT ++GL+ T Y +V A+
Sbjct: 826 IAWNRNTGRVLGYEVLY--WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAY 882
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
AG G + PV T++ PS P A + +K+ ++W
Sbjct: 883 NTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNW 923
Score = 54.8 bits (126), Expect = 2e-06
Identities = 40/161 (24%), Positives = 75/161 (46%), Gaps = 4/161 (2%)
Query: 73 PKNIRVIDQQSRTIQISWTQ-PYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P+ + + +++SW + N+ ++ Y V Y +S S K+ V G+VT+
Sbjct: 806 PRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYW-TDDSKESMIGKIRVSGNVTTK 864
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ L+ T Y + A N G S PV VTT + PS PP ++ + +S +L + W
Sbjct: 865 NITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNS-KLCLNW 923
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTV 231
E + +LGY + +++ + T ++ + A V
Sbjct: 924 EHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLV 964
Score = 50.8 bits (116), Expect = 3e-05
Identities = 84/371 (22%), Positives = 136/371 (36%), Gaps = 26/371 (7%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PP +Q +SS + ++SW P N +Q + + T P + + V + ++
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGP--DNNSPIQIFTIQTRTPFSVGWQAVATVPEILN 654
Query: 342 G--LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP-VYCHTEEDVP-SAPADIKAAVSSR 397
G + T+ GL + Y V A + G G + P T+ VP AP +I SR
Sbjct: 655 GKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSR 714
Query: 398 NKILVSW--LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
++++++W +P NG GY + + + S + P +
Sbjct: 715 SELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPF 774
Query: 456 QFWVSASTRLGEGEATRVVTVLPSDSVP------ARITSFSRNIVTPWKENISLSCNKVG 509
+ V GEG + V V + P + SFS + + I+ + N
Sbjct: 775 EVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGR 834
Query: 510 VPA-PATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVE--NIHG----RD 562
V WT + ES + K S T ++T + Y SV N G
Sbjct: 835 VLGYEVLYWTDD--SKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSP 892
Query: 563 EVTYTVEVKVPPQPPILAVVDSYADSLHLQWS--DQGDGGSPILGYVINYKREHGDWEEL 620
V T + P QPP L L W + S +LGY I Y++ +
Sbjct: 893 PVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHI 952
Query: 621 QVEAGTSEHVL 631
TS +L
Sbjct: 953 LETNNTSAELL 963
Score = 49.2 bits (112), Expect = 8e-05
Identities = 55/230 (23%), Positives = 93/230 (40%), Gaps = 16/230 (6%)
Query: 534 SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP-ILAVVDSYADSLHLQ 592
S G L I Q SG Y C+V+ + V+ PP PP + V D + + L
Sbjct: 558 SVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLS 617
Query: 593 WSDQGDGGSPILGYVINYKREHG-DWEELQ-----VEAGTSEHVLPNLWCGTRYQLYITA 646
W D SPI + I + W+ + + T + L Y+ + A
Sbjct: 618 WRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVA 677
Query: 647 FNRIGTGLPCDIVHAY-TKGTVPVKPK---HSQMITLNTTTVTVW--LDSWGDGGCGILY 700
N IG G P + TK +VPV H + + +T W + G G Y
Sbjct: 678 GNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVIT-WESIPEELQNGEGFGY 736
Query: 701 FVIEYREMSQPQW-RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+I +R + W + +SV+++ V+ + P + +++++ +NN G
Sbjct: 737 -IIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEG 785
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
+N+ C G P P TW NG L R + + GTL I+M +DSG Y C+ EN
Sbjct: 333 DNLLWECKASGKPNPWYTWLKNGERLNPEERIQIEN-GTLIITMLNVSDSGVYQCAAEN 390
Score = 44.0 bits (99), Expect = 0.003
Identities = 60/263 (22%), Positives = 108/263 (41%), Gaps = 19/263 (7%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+I + C P A +W L + R + DG+L I +D+G+YTC N
Sbjct: 426 DIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQF 485
Query: 560 GRDEVTYTVEVK---VPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINY 610
G + T ++ VK V PP V + +S+ L D ++ G VI+
Sbjct: 486 GTAKNTGSLIVKERTVITVPPSKMDV-TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDL 544
Query: 611 KREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI-GTGLPCDIVHAYTKGTVPV 669
K+ +E + E+ + ++ N+ + T + DI+ +G P
Sbjct: 545 KKGVAHFERIGGES-VGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADII---VRGP-PG 599
Query: 670 KPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF- 727
P+ Q+ +++TT + + D I F I+ R W+ V+ + + +
Sbjct: 600 PPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYN 659
Query: 728 -SVSGLTPAAHYQLRITAHNNAG 749
+V GL+P Y+ R+ A N+ G
Sbjct: 660 ATVVGLSPWVEYEFRVVAGNSIG 682
Score = 39.1 bits (87), Expect = 0.086
Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 4/140 (2%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSSDGTLTISMTQSAD 547
F I ++ L C +G P P +W ++G L ++ + S L I Q D
Sbjct: 233 FPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYS-KSQAILEIPNFQQED 291
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDG-GSPILGY 606
G Y C N+ GR+ + PP+ + +L W + G +P +
Sbjct: 292 EGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTW 351
Query: 607 VINYKREHGDWEELQVEAGT 626
+ N +R + + E +Q+E GT
Sbjct: 352 LKNGERLNPE-ERIQIENGT 370
Score = 37.1 bits (82), Expect = 0.35
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTISMTQS-ADSGNYTCSV 555
K + L+C G P+P W NG ++ T+ + D G+L I+ + D G Y C
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
Query: 556 ENIHG 560
N+ G
Sbjct: 103 TNLLG 107
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 118 bits (285), Expect = 9e-26
Identities = 96/375 (25%), Positives = 157/375 (41%), Gaps = 23/375 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTP-QKVIVPGSV 127
P P +R+ D ++ ++ ++W++ +SPI Y +Q K + W I+ G++
Sbjct: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A +L P Y R++A N LG+ EPS P ++ T P+ P DV + EL
Sbjct: 664 EAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNREL 723
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+TW P R+ GN GY V F+ + G + TV T R
Sbjct: 724 TITWAPLSREYHYGNNFGYIVAFKPFD------------GEEWKKVTVTNPDTGRYVHKD 771
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ A+ V V+A+N++ +D PS P + LSS + V WE
Sbjct: 772 ETMSPSTAFQVKVKAFNNKGDGPYSLLAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE- 830
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
I++ Y++ Y D + V L L T Y + V A +A
Sbjct: 831 ---HVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSA 887
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPNGVLVGY-TLYM-S 422
G G + + T++ PS P I ++V S ++ +++W + S + GY LY
Sbjct: 888 GCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPD 947
Query: 423 VIEDGREEGTHKRML 437
DG+ THK +
Sbjct: 948 GQHDGKLYSTHKHSI 962
Score = 49.2 bits (112), Expect = 8e-05
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
I S E P + V S I + W + + +Y ++Y A + +V
Sbjct: 801 INSAQDAPSEAPTEVGVKVLSSSEISVHWE--HVLEKIVESYQIRYWAAHDK-EEAANRV 857
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
V SA ++NL P T Y + + A N G PS ++ T + PS PP+ + +
Sbjct: 858 QVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIIS-SVR 916
Query: 182 SSTELIVTWE 191
S + I+TW+
Sbjct: 917 SGSRYIITWD 926
Score = 46.0 bits (104), Expect = 7e-04
Identities = 53/262 (20%), Positives = 101/262 (38%), Gaps = 18/262 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P +W+ L ++ R + DG+L I+ D G YTC EN G
Sbjct: 432 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRG 491
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T T+ + P + PI A + + ++ +Q + D + GYVI++
Sbjct: 492 KANSTGTLVITDPTRIILAPINADI-TVGENATMQCAASFDPALDLTFVWSFNGYVIDFN 550
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI-GTGLPCDIVHAYTKGTVPVK 670
+E+ ++ + E ++ N + TA + + D+V +G P
Sbjct: 551 KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLV---VRGP-PGP 606
Query: 671 PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS---VQATERVF 727
P ++ + T+V + D I + I+ + + W+ ++
Sbjct: 607 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAA 666
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
L P Y+ R+ A N G
Sbjct: 667 RAVDLIPWMEYEFRVVATNTLG 688
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
PA I +++ +N++L C +G P P W + ST + S L I
Sbjct: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-AVLKIFN 299
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D G Y C ENI G+D+ + V+ P+
Sbjct: 300 IQLEDEGIYECEAENIRGKDKHQARIYVQAFPE 332
Score = 35.9 bits (79), Expect = 0.80
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHV--LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y I Y H D EE +V+ + E+ L NL T+Y + + A N G G P D++ A
Sbjct: 840 YQIRYWAAH-DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 898
Query: 662 YTKGTVPVKP 671
+TK P +P
Sbjct: 899 FTKKAPPSQP 908
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI-SMTQSADSGNYTCSVENIH 559
+SL+C P P W MN ++ T + G L I + + D+G Y C N +
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 120
Query: 560 G 560
G
Sbjct: 121 G 121
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 118 bits (285), Expect = 9e-26
Identities = 96/375 (25%), Positives = 157/375 (41%), Gaps = 23/375 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTP-QKVIVPGSV 127
P P +R+ D ++ ++ ++W++ +SPI Y +Q K + W I+ G++
Sbjct: 593 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 652
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A +L P Y R++A N LG+ EPS P ++ T P+ P DV + EL
Sbjct: 653 EAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNREL 712
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+TW P R+ GN GY V F+ + G + TV T R
Sbjct: 713 TITWAPLSREYHYGNNFGYIVAFKPFD------------GEEWKKVTVTNPDTGRYVHKD 760
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ A+ V V+A+N++ +D PS P + LSS + V WE
Sbjct: 761 ETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE- 819
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
I++ Y++ Y D + V L L T Y + V A +A
Sbjct: 820 ---HVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSA 876
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPNGVLVGY-TLYM-S 422
G G + + T++ PS P I ++V S ++ +++W + S + GY LY
Sbjct: 877 GCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPD 936
Query: 423 VIEDGREEGTHKRML 437
DG+ THK +
Sbjct: 937 GQHDGKLYSTHKHSI 951
Score = 49.2 bits (112), Expect = 8e-05
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
I S E P + V S I + W + + +Y ++Y A + +V
Sbjct: 790 INSAQDAPSEAPTEVGVKVLSSSEISVHWE--HVLEKIVESYQIRYWAAHDK-EEAANRV 846
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
V SA ++NL P T Y + + A N G PS ++ T + PS PP+ + +
Sbjct: 847 QVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIIS-SVR 905
Query: 182 SSTELIVTWE 191
S + I+TW+
Sbjct: 906 SGSRYIITWD 915
Score = 46.0 bits (104), Expect = 7e-04
Identities = 53/262 (20%), Positives = 101/262 (38%), Gaps = 18/262 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P +W+ L ++ R + DG+L I+ D G YTC EN G
Sbjct: 421 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRG 480
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T T+ + P + PI A + + ++ +Q + D + GYVI++
Sbjct: 481 KANSTGTLVITDPTRIILAPINADI-TVGENATMQCAASFDPALDLTFVWSFNGYVIDFN 539
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI-GTGLPCDIVHAYTKGTVPVK 670
+E+ ++ + E ++ N + TA + + D+V +G P
Sbjct: 540 KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLV---VRGP-PGP 595
Query: 671 PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS---VQATERVF 727
P ++ + T+V + D I + I+ + + W+ ++
Sbjct: 596 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAA 655
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
L P Y+ R+ A N G
Sbjct: 656 RAVDLIPWMEYEFRVVATNTLG 677
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
PA I +++ +N++L C +G P P W + ST + S L I
Sbjct: 230 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-AVLKIFN 288
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D G Y C ENI G+D+ + V+ P+
Sbjct: 289 IQLEDEGIYECEAENIRGKDKHQARIYVQAFPE 321
Score = 35.9 bits (79), Expect = 0.80
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHV--LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y I Y H D EE +V+ + E+ L NL T+Y + + A N G G P D++ A
Sbjct: 829 YQIRYWAAH-DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 887
Query: 662 YTKGTVPVKP 671
+TK P +P
Sbjct: 888 FTKKAPPSQP 897
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI-SMTQSADSGNYTCSVENIH 559
+SL+C P P W MN ++ T + G L I + + D+G Y C N +
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 109
Query: 560 G 560
G
Sbjct: 110 G 110
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 118 bits (285), Expect = 9e-26
Identities = 96/375 (25%), Positives = 157/375 (41%), Gaps = 23/375 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEA-PESWPSTP-QKVIVPGSV 127
P P +R+ D ++ ++ ++W++ +SPI Y +Q K + W I+ G++
Sbjct: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPV-QVTTTEEVPSGPPQDVRVEAKSSTEL 186
+A +L P Y R++A N LG+ EPS P ++ T P+ P DV + EL
Sbjct: 664 EAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNREL 723
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
+TW P R+ GN GY V F+ + G + TV T R
Sbjct: 724 TITWAPLSREYHYGNNFGYIVAFKPFD------------GEEWKKVTVTNPDTGRYVHKD 771
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ A+ V V+A+N++ +D PS P + LSS + V WE
Sbjct: 772 ETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE- 830
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
I++ Y++ Y D + V L L T Y + V A +A
Sbjct: 831 ---HVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSA 887
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPNGVLVGY-TLYM-S 422
G G + + T++ PS P I ++V S ++ +++W + S + GY LY
Sbjct: 888 GCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPD 947
Query: 423 VIEDGREEGTHKRML 437
DG+ THK +
Sbjct: 948 GQHDGKLYSTHKHSI 962
Score = 49.2 bits (112), Expect = 8e-05
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
I S E P + V S I + W + + +Y ++Y A + +V
Sbjct: 801 INSAQDAPSEAPTEVGVKVLSSSEISVHWE--HVLEKIVESYQIRYWAAHDK-EEAANRV 857
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
V SA ++NL P T Y + + A N G PS ++ T + PS PP+ + +
Sbjct: 858 QVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIIS-SVR 916
Query: 182 SSTELIVTWE 191
S + I+TW+
Sbjct: 917 SGSRYIITWD 926
Score = 46.0 bits (104), Expect = 7e-04
Identities = 53/262 (20%), Positives = 101/262 (38%), Gaps = 18/262 (6%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ + C P P +W+ L ++ R + DG+L I+ D G YTC EN G
Sbjct: 432 VIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRG 491
Query: 561 RDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPIL------GYVINYK 611
+ T T+ + P + PI A + + ++ +Q + D + GYVI++
Sbjct: 492 KANSTGTLVITDPTRIILAPINADI-TVGENATMQCAASFDPALDLTFVWSFNGYVIDFN 550
Query: 612 REHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRI-GTGLPCDIVHAYTKGTVPVK 670
+E+ ++ + E ++ N + TA + + D+V +G P
Sbjct: 551 KENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLV---VRGP-PGP 606
Query: 671 PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS---VQATERVF 727
P ++ + T+V + D I + I+ + + W+ ++
Sbjct: 607 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAA 666
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
L P Y+ R+ A N G
Sbjct: 667 RAVDLIPWMEYEFRVVATNTLG 688
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
PA I +++ +N++L C +G P P W + ST + S L I
Sbjct: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-AVLKIFN 299
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D G Y C ENI G+D+ + V+ P+
Sbjct: 300 IQLEDEGIYECEAENIRGKDKHQARIYVQAFPE 332
Score = 35.9 bits (79), Expect = 0.80
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHV--LPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
Y I Y H D EE +V+ + E+ L NL T+Y + + A N G G P D++ A
Sbjct: 840 YQIRYWAAH-DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 898
Query: 662 YTKGTVPVKP 671
+TK P +P
Sbjct: 899 FTKKAPPSQP 908
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI-SMTQSADSGNYTCSVENIH 559
+SL+C P P W MN ++ T + G L I + + D+G Y C N +
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 120
Query: 560 G 560
G
Sbjct: 121 G 121
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 109 bits (262), Expect = 5e-23
Identities = 111/455 (24%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 70 PEMPKNIRVIDQQSR-TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV--IVPGS 126
P P I ++++ + T +SW+ +SPI +Y +Q + T + V I+ G
Sbjct: 670 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGD 729
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+ SA +L P Y R++A N +G +PS P + + T E VP P +V + E
Sbjct: 730 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 789
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++ WEP + NG GY V F+ N T G V + E + +
Sbjct: 790 LVIAWEPVSEEFQNGEGFGYIVAFR---PNGT------RGWKEKMVTSSEASKFIYRDES 840
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ L + V V YN++ E PS P ++ ++S + V+W+
Sbjct: 841 VPPL---TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK 897
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
++ G QG+ V Y + + V + + L+GL T Y TV A+
Sbjct: 898 --HIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNG 955
Query: 366 AGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMS 422
AG G ++ V T++ PS AP++++ +++ + W P P + +VGY ++
Sbjct: 956 AGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY- 1013
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
R+EG + + P + V A + G+G A+ + V PS S
Sbjct: 1014 -----RQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRV-PSYS- 1066
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ITS + T + S++ + + P+T+W
Sbjct: 1067 GGKITSAQSTLHTLSTSSSSVTL-LLALMIPSTSW 1100
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A + G A+ + +L S A + + I+ + + + C G P P +W
Sbjct: 460 AENKYGAIYASAELKILASAPTFA-LNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKG 518
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL- 579
+ R + DG+L I +D G Y C EN+ G E+ ++ VK P + +
Sbjct: 519 DRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTP 578
Query: 580 -AVVDSYADSLHLQWSDQGDGGSPIL------GYVINYKREHGDWEELQVEAGTSEHVLP 632
+ +S+ L D + G I+++ E G +E ++ +A +++ ++
Sbjct: 579 KRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIR 638
Query: 633 NL 634
N+
Sbjct: 639 NI 640
Score = 52.8 bits (121), Expect = 7e-06
Identities = 88/431 (20%), Positives = 166/431 (38%), Gaps = 36/431 (8%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PPG + ++ + +SW P + + Y + +P + + V + I+
Sbjct: 670 PPGPPGIVIVEEITESTATLSWS--PAADNHSPISSYNLQARSPFSLGWQTVKTVPEIIT 727
Query: 342 G-LHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPV-YCHTEEDVP-SAPADIKAAVSSR 397
G + + ++ L + Y V A G G + P T E VP +AP ++ R
Sbjct: 728 GDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRR 787
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS---HETSRSPPR 452
++++++W P S NG GY + G ++M++ S S + PP
Sbjct: 788 HELVIAWEPVSEEFQNGEGFGYIV---AFRPNGTRGWKEKMVTSSEASKFIYRDESVPPL 844
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVPA------RITSFS-RNIVTPWKENISLSC 505
+ V G+G +++V + ++ P+ + TS S I+ WK +I S
Sbjct: 845 TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK-HIKES- 902
Query: 506 NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG----- 560
+G P + E T + + +T + Y +V +G
Sbjct: 903 --LGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGP 960
Query: 561 -RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDW 617
EV+ T + P Q P + + L W S ++GY + Y++E G
Sbjct: 961 PSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQE-GHS 1019
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI 677
+E + V+P G Y + + A++ G G + + + S +
Sbjct: 1020 NSQVIETQKLQAVVPLPDAGV-YIIEVRAYSEGGDGTASSQIRVPSYSGGKITSAQSTLH 1078
Query: 678 TLNTTTVTVWL 688
TL+T++ +V L
Sbjct: 1079 TLSTSSSSVTL 1089
Score = 49.2 bits (112), Expect = 8e-05
Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLE--------STLRKNV 532
P RI + E+I L+C + + T WT+ G ++ ++R
Sbjct: 571 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 630
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV--PPQPPILAVVDSYADSLH 590
SS L I +G Y C V+ D V+ E+ V PP PP + +V+ +S
Sbjct: 631 SS-ADLMIRNILLMHAGRYGCRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEEITESTA 687
Query: 591 -LQWSDQGDGGSPILGYVINYKREHG-DWEEL----QVEAGTSEHVLP---NLWCGTRYQ 641
L WS D SPI Y + + W+ + ++ G E + N W Y+
Sbjct: 688 TLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPW--VEYE 745
Query: 642 LYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKH-SQMITLNTTTVTVW--LDSWGDGGC 696
+ A N IGTG P T VP P + S V W + G
Sbjct: 746 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 805
Query: 697 GILYFVIEYREMSQPQWR-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G Y ++ +R W+ + S +A++ ++ + P +++++ +NN G
Sbjct: 806 GFGY-IVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKG 858
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTIS-MTQSADSGNYTCS 554
++ ++L+C G P P+ W NG + LES R ++ DGT IS +++ DSG+Y C
Sbjct: 116 EKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSL-IDGTFIISNPSEAKDSGHYQCL 174
Query: 555 VENIHG 560
N G
Sbjct: 175 ATNTVG 180
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
C G P P W NGV L R + +G L I +D+G Y C EN +G +
Sbjct: 411 CKATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYG--AI 467
Query: 565 TYTVEVKVPPQPPILAV 581
+ E+K+ P A+
Sbjct: 468 YASAELKILASAPTFAL 484
Score = 39.1 bits (87), Expect = 0.086
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 501 ISLSCNKVGVPAPATTWT-MNG-VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ + C +G P P TW +NG + ++ LRK S L I Q D+G Y C EN
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYIPSKARLRK---SQAVLEIPNVQLDDAGIYECRAENS 374
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQGDG 599
G++ ++V P + + D+ DS L+W + G
Sbjct: 375 RGKNSFRGQLQVYTYPH-WVEKLNDTQLDSGSPLRWECKATG 415
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 107 bits (258), Expect = 2e-22
Identities = 110/455 (24%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 70 PEMPKNIRVIDQQSR-TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV--IVPGS 126
P P I ++++ + T +SW+ +SPI +Y +Q + T + V I+ G
Sbjct: 596 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGD 655
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+ SA +L P Y R++A N +G +PS P + + T E VP P +V + E
Sbjct: 656 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 715
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++ WEP + NG GY V F+ N T G V + E + +
Sbjct: 716 LVIAWEPVSEEFQNGEGFGYIVAFR---PNGT------RGWKEKMVTSSEASKFIYRDES 766
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ L + V V YN++ E PS P ++ ++S + V+W+
Sbjct: 767 VPPL---TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK 823
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
++ G QG+ V Y + + V + + L+GL T Y TV A+
Sbjct: 824 --HIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNG 881
Query: 366 AGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMS 422
AG G ++ V T++ PS AP++++ +++ + W P P + +VGY ++
Sbjct: 882 AGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY- 939
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
R+EG + + P + V A + G+G A+ + V PS S
Sbjct: 940 -----RQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRV-PSYS- 992
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ITS + + + S++ + + P+T+W
Sbjct: 993 GGKITSAQSTLHSLSTSSSSVTL-LLALMIPSTSW 1026
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A + G A+ + +L S A + + I+ + + + C G P P +W
Sbjct: 386 AENKYGAIYASAELKILASAPTFA-LNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKG 444
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL- 579
+ R + DG+L I +D G Y C EN+ G E+ ++ VK P + +
Sbjct: 445 DRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTP 504
Query: 580 -AVVDSYADSLHLQWSDQGDGGSPIL------GYVINYKREHGDWEELQVEAGTSEHVLP 632
+ +S+ L D + G I+++ E G +E ++ +A +++ ++
Sbjct: 505 KRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIR 564
Query: 633 NL 634
N+
Sbjct: 565 NI 566
Score = 51.2 bits (117), Expect = 2e-05
Identities = 87/431 (20%), Positives = 166/431 (38%), Gaps = 36/431 (8%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PPG + ++ + +SW P + + Y + +P + + V + I+
Sbjct: 596 PPGPPGIVIVEEITESTATLSWS--PAADNHSPISSYNLQARSPFSLGWQTVKTVPEIIT 653
Query: 342 G-LHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPV-YCHTEEDVP-SAPADIKAAVSSR 397
G + + ++ L + Y V A G G + P T E VP +AP ++ R
Sbjct: 654 GDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRR 713
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS---HETSRSPPR 452
++++++W P S NG GY + G ++M++ S S + PP
Sbjct: 714 HELVIAWEPVSEEFQNGEGFGYIV---AFRPNGTRGWKEKMVTSSEASKFIYRDESVPPL 770
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVPA------RITSFS-RNIVTPWKENISLSC 505
+ V G+G +++V + ++ P+ + TS S I+ WK +I S
Sbjct: 771 TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK-HIKES- 828
Query: 506 NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG----- 560
+G P + E T + + +T + Y +V +G
Sbjct: 829 --LGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGP 886
Query: 561 -RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDW 617
EV+ T + P Q P + + L W S ++GY + Y++E G
Sbjct: 887 PSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQE-GHS 945
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI 677
+E + V+P G Y + + A++ G G + + + S +
Sbjct: 946 NSQVIETQKLQAVVPLPDAGV-YIIEVRAYSEGGDGTASSQIRVPSYSGGKITSAQSTLH 1004
Query: 678 TLNTTTVTVWL 688
+L+T++ +V L
Sbjct: 1005 SLSTSSSSVTL 1015
Score = 49.2 bits (112), Expect = 8e-05
Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLE--------STLRKNV 532
P RI + E+I L+C + + T WT+ G ++ ++R
Sbjct: 497 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 556
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV--PPQPPILAVVDSYADSLH 590
SS L I +G Y C V+ D V+ E+ V PP PP + +V+ +S
Sbjct: 557 SS-ADLMIRNILLMHAGRYGCRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEEITESTA 613
Query: 591 -LQWSDQGDGGSPILGYVINYKREHG-DWEEL----QVEAGTSEHVLP---NLWCGTRYQ 641
L WS D SPI Y + + W+ + ++ G E + N W Y+
Sbjct: 614 TLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPW--VEYE 671
Query: 642 LYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKH-SQMITLNTTTVTVW--LDSWGDGGC 696
+ A N IGTG P T VP P + S V W + G
Sbjct: 672 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 731
Query: 697 GILYFVIEYREMSQPQWR-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G Y ++ +R W+ + S +A++ ++ + P +++++ +NN G
Sbjct: 732 GFGY-IVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKG 784
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTIS-MTQSADSGNYTCS 554
++ ++L+C G P P+ W NG + LES R ++ DGT IS +++ DSG+Y C
Sbjct: 42 EKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSL-IDGTFIISNPSEAKDSGHYQCL 100
Query: 555 VENIHG 560
N G
Sbjct: 101 ATNTVG 106
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
C G P P W NGV L R + +G L I +D+G Y C EN +G +
Sbjct: 337 CKATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYG--AI 393
Query: 565 TYTVEVKVPPQPPILAV 581
+ E+K+ P A+
Sbjct: 394 YASAELKILASAPTFAL 410
Score = 39.1 bits (87), Expect = 0.086
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 501 ISLSCNKVGVPAPATTWT-MNG-VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ + C +G P P TW +NG + ++ LRK S L I Q D+G Y C EN
Sbjct: 244 VKMECFALGNPVPTITWMKVNGYIPSKARLRK---SQAVLEIPNVQLDDAGIYECRAENS 300
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQGDG 599
G++ ++V P + + D+ DS L+W + G
Sbjct: 301 RGKNSFRGQLQVYTYPH-WVEKLNDTQLDSGSPLRWECKATG 341
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 107 bits (258), Expect = 2e-22
Identities = 110/455 (24%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 70 PEMPKNIRVIDQQSR-TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV--IVPGS 126
P P I ++++ + T +SW+ +SPI +Y +Q + T + V I+ G
Sbjct: 670 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGD 729
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+ SA +L P Y R++A N +G +PS P + + T E VP P +V + E
Sbjct: 730 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 789
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++ WEP + NG GY V F+ N T G V + E + +
Sbjct: 790 LVIAWEPVSEEFQNGEGFGYIVAFR---PNGT------RGWKEKMVTSSEASKFIYRDES 840
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ L + V V YN++ E PS P ++ ++S + V+W+
Sbjct: 841 VPPL---TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK 897
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
++ G QG+ V Y + + V + + L+GL T Y TV A+
Sbjct: 898 --HIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNG 955
Query: 366 AGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLP--PSSPNGVLVGYTLYMS 422
AG G ++ V T++ PS AP++++ +++ + W P P + +VGY ++
Sbjct: 956 AGYGPPSSEVSATTKKSPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY- 1013
Query: 423 VIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
R+EG + + P + V A + G+G A+ + V PS S
Sbjct: 1014 -----RQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRV-PSYS- 1066
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTW 517
+ITS + + + S++ + + P+T+W
Sbjct: 1067 GGKITSAQSTLHSLSTSSSSVTL-LLALMIPSTSW 1100
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A + G A+ + +L S A + + I+ + + + C G P P +W
Sbjct: 460 AENKYGAIYASAELKILASAPTFA-LNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKG 518
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL- 579
+ R + DG+L I +D G Y C EN+ G E+ ++ VK P + +
Sbjct: 519 DRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTP 578
Query: 580 -AVVDSYADSLHLQWSDQGDGGSPIL------GYVINYKREHGDWEELQVEAGTSEHVLP 632
+ +S+ L D + G I+++ E G +E ++ +A +++ ++
Sbjct: 579 KRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIR 638
Query: 633 NL 634
N+
Sbjct: 639 NI 640
Score = 51.2 bits (117), Expect = 2e-05
Identities = 87/431 (20%), Positives = 166/431 (38%), Gaps = 36/431 (8%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PPG + ++ + +SW P + + Y + +P + + V + I+
Sbjct: 670 PPGPPGIVIVEEITESTATLSWS--PAADNHSPISSYNLQARSPFSLGWQTVKTVPEIIT 727
Query: 342 G-LHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPV-YCHTEEDVP-SAPADIKAAVSSR 397
G + + ++ L + Y V A G G + P T E VP +AP ++ R
Sbjct: 728 GDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRR 787
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS---HETSRSPPR 452
++++++W P S NG GY + G ++M++ S S + PP
Sbjct: 788 HELVIAWEPVSEEFQNGEGFGYIV---AFRPNGTRGWKEKMVTSSEASKFIYRDESVPPL 844
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVPA------RITSFS-RNIVTPWKENISLSC 505
+ V G+G +++V + ++ P+ + TS S I+ WK +I S
Sbjct: 845 TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK-HIKES- 902
Query: 506 NKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG----- 560
+G P + E T + + +T + Y +V +G
Sbjct: 903 --LGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGP 960
Query: 561 -RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD--QGDGGSPILGYVINYKREHGDW 617
EV+ T + P Q P + + L W S ++GY + Y++E G
Sbjct: 961 PSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQE-GHS 1019
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI 677
+E + V+P G Y + + A++ G G + + + S +
Sbjct: 1020 NSQVIETQKLQAVVPLPDAGV-YIIEVRAYSEGGDGTASSQIRVPSYSGGKITSAQSTLH 1078
Query: 678 TLNTTTVTVWL 688
+L+T++ +V L
Sbjct: 1079 SLSTSSSSVTL 1089
Score = 49.2 bits (112), Expect = 8e-05
Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLE--------STLRKNV 532
P RI + E+I L+C + + T WT+ G ++ ++R
Sbjct: 571 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 630
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV--PPQPPILAVVDSYADSLH 590
SS L I +G Y C V+ D V+ E+ V PP PP + +V+ +S
Sbjct: 631 SS-ADLMIRNILLMHAGRYGCRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEEITESTA 687
Query: 591 -LQWSDQGDGGSPILGYVINYKREHG-DWEEL----QVEAGTSEHVLP---NLWCGTRYQ 641
L WS D SPI Y + + W+ + ++ G E + N W Y+
Sbjct: 688 TLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPW--VEYE 745
Query: 642 LYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKH-SQMITLNTTTVTVW--LDSWGDGGC 696
+ A N IGTG P T VP P + S V W + G
Sbjct: 746 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 805
Query: 697 GILYFVIEYREMSQPQWR-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G Y ++ +R W+ + S +A++ ++ + P +++++ +NN G
Sbjct: 806 GFGY-IVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKG 858
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 498 KENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTIS-MTQSADSGNYTCS 554
++ ++L+C G P P+ W NG + LES R ++ DGT IS +++ DSG+Y C
Sbjct: 116 EKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSL-IDGTFIISNPSEAKDSGHYQCL 174
Query: 555 VENIHG 560
N G
Sbjct: 175 ATNTVG 180
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
C G P P W NGV L R + +G L I +D+G Y C EN +G +
Sbjct: 411 CKATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYG--AI 467
Query: 565 TYTVEVKVPPQPPILAV 581
+ E+K+ P A+
Sbjct: 468 YASAELKILASAPTFAL 484
Score = 39.1 bits (87), Expect = 0.086
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 501 ISLSCNKVGVPAPATTWT-MNG-VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ + C +G P P TW +NG + ++ LRK S L I Q D+G Y C EN
Sbjct: 318 VKMECFALGNPVPTITWMKVNGYIPSKARLRK---SQAVLEIPNVQLDDAGIYECRAENS 374
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQGDG 599
G++ ++V P + + D+ DS L+W + G
Sbjct: 375 RGKNSFRGQLQVYTYPH-WVEKLNDTQLDSGSPLRWECKATG 415
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 106 bits (254), Expect = 5e-22
Identities = 100/347 (28%), Positives = 154/347 (44%), Gaps = 44/347 (12%)
Query: 134 NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
+++ + +YH +A + LG E + V + + P P V ++T + +TW
Sbjct: 289 DVKDSANYH-PCVAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW--- 340
Query: 194 QRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHA 253
D N + + YYV E S S GP Y ++ E T +R ++ GL ++
Sbjct: 341 --DSGNPDPVSYYV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNS 384
Query: 254 AYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRN 313
Y + V A NS E P+ PP +Q LS+ ++ V WE P N
Sbjct: 385 EYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVEP--N 442
Query: 314 GILQGYRVTYA-----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G+++GYRV Y PV +W N D L TT+ L Y+V V AFT+ G
Sbjct: 443 GLIRGYRVYYTMEPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVG 496
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDG 427
DG + P+ T++ VP P +++A S I +SW PP + ++ Y L + G
Sbjct: 497 DGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHG 554
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV 474
RE G R P+T S+ P + F ++A + G G T VV
Sbjct: 555 REVG---RTFDPTT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 597
Score = 91.1 bits (216), Expect = 2e-17
Identities = 87/344 (25%), Positives = 148/344 (43%), Gaps = 32/344 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 319 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 372
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ PP++V+ S+T +I
Sbjct: 373 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMI 432
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 433 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 477
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 478 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 536
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R + Y + + +G E T + + + L+ T Y+ + A + G
Sbjct: 537 ----RQESIIKYELLFREGD--HGREVGRTFDPTTSY-VVEDLKPNTEYAFRLAARSPQG 589
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
G V T + + +P + K + + +L+SW P + N
Sbjct: 590 LGAFTPVVRQRTLQSI--SPKNFKVKMIMKTSVLLSWEFPDNYN 631
Score = 74.1 bits (174), Expect = 2e-12
Identities = 66/255 (25%), Positives = 111/255 (43%), Gaps = 11/255 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY-TCSVENI 558
N++++C VG P P W G E ++ G + +T DS NY C +
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYHPCVAMSS 304
Query: 559 HGRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDW 617
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 305 LGVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGNP-DPVSYYVIEYKSKSQDG 362
Query: 618 E-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQ 675
+++ + T+ + + L + Y+++++A N IG G P + V T P + P++ Q
Sbjct: 363 PYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQ 422
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 423 ARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLE 481
Query: 735 AAHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 482 DETYTVRVLAFTSVG 496
Score = 52.8 bits (121), Expect = 7e-06
Identities = 73/310 (23%), Positives = 125/310 (40%), Gaps = 22/310 (7%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + + A +GE +TVL D +P+ + V ++ C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 508 VGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG---R 561
G P P TW + + ++ S R G L I ++ D G Y C N G
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 562 DEVTYTVEV-KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL 620
V V +V P+ IL + ++ + GSP + YV + E
Sbjct: 219 SPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVA-VGSP-MPYVKWMQGAEDLTPED 276
Query: 621 QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ G + L ++ Y + A + +G + V T ++P P + M+T N
Sbjct: 277 DMPVGRNVLELTDVKDSANYHPCV-AMSSLGV---IEAVAQITVKSLPKAP-GTPMVTEN 331
Query: 681 T-TTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
T T++T+ DS + Y+VIEY+ SQ + + T +S+ GL+P + Y+
Sbjct: 332 TATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTTR--YSIGGLSPNSEYE 387
Query: 740 LRITAHNNAG 749
+ ++A N+ G
Sbjct: 388 IWVSAVNSIG 397
Score = 44.0 bits (99), Expect = 0.003
Identities = 69/323 (21%), Positives = 127/323 (39%), Gaps = 27/323 (8%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLS 438
T + +P AP ++ I ++W S N V Y Y+ + ++G ++
Sbjct: 315 TVKSLPKAPGTPMVTENTATSITITW---DSGNPDPVSY--YVIEYKSKSQDGPYQIKED 369
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITS-------FSR 491
+T + P + ++ WVSA +G+G + V + PAR +
Sbjct: 370 ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSAT 429
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY 551
++ W+E + + G T + VG + + NV D +L ++ + Y
Sbjct: 430 TMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVG--NWQKHNV--DDSLLTTVGSLLEDETY 485
Query: 552 TCSVENIH--GRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
T V G ++ ++VK VP QP L S+ L WS I+
Sbjct: 486 TVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ--ESIIK 543
Query: 606 YVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
Y + ++ +HG E + T+ +V+ +L T Y + A + G G +V T
Sbjct: 544 YELLFREGDHGR-EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTL 602
Query: 665 GTVPVKPKHSQMITLNTTTVTVW 687
++ K +MI + T+ + W
Sbjct: 603 QSISPKNFKVKMI-MKTSVLLSW 624
>X64698-1|CAA45939.1| 1100|Homo sapiens titin protein.
Length = 1100
Score = 105 bits (252), Expect = 9e-22
Identities = 161/683 (23%), Positives = 267/683 (39%), Gaps = 54/683 (7%)
Query: 95 AGNSPIINYI-VQYKEAPESWPSTPQKVIVPGSVT------SASVQNLQPAT---SYHLR 144
AG++ ++N I + K P+S S K I P +T ++S+ ++ AT +
Sbjct: 299 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 358
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILG 204
I A N G + V+VT + VP GPP V + S+ + +TW PP D G+ +
Sbjct: 359 ITATNPFGTKV--EHVKVTVLD-VP-GPPGPVEISNVSAEKATLTWTPPLED--GGSPIK 412
Query: 205 YYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNS 264
Y+ L T S + TV R + L + Y V A N
Sbjct: 413 SYI----LEKRET----------SRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNH 458
Query: 265 RXXXXXXXXXXXXXMEDV-PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
++ P PP + + ++ + VSW+ P G + I GY V
Sbjct: 459 YGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEIT-GYHVER 517
Query: 324 APVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV 383
A+ +S L ++GL+ + Y V A AG G + +D
Sbjct: 518 REKKSLRWVR-AIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA 576
Query: 384 ---PSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLS 438
P P++ +++ ++W P G+ + GY + + V ++ + T L
Sbjct: 577 AYPPGPPSNPHVTDTTKKSASLAWGKPHIDGGLEITGYVVEHQKVGDEAWIKDTTGTALR 636
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--VTVLPSDSVP--ARITSFSRNIV 494
+ ++ + + F +SA G GE + V ++ + P R +V
Sbjct: 637 ITQFVVPDLQTKEK--YNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLV 694
Query: 495 TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSADSGNYTC 553
+I + G PAP TWT + + L++ +N S L I D+G +
Sbjct: 695 VRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVM 754
Query: 554 SVENIHGRDEVTYTVEVKVPPQP-PILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYK 611
++EN G+ V V +P P L D DS+ L W DGGS I Y++ K
Sbjct: 755 TIENPAGKKSGFVNVRVLDTARPSPQLRPTDITKDSVTLHWDLPLIDGGSRITNYIVE-K 813
Query: 612 RE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV 669
RE + + + + L G Y + A N G G P + P
Sbjct: 814 REATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS 873
Query: 670 KPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFS 728
P ++ + +TV++ W DGG I +VIE + QW ++ +V+ E V
Sbjct: 874 PPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHIT-TVKGLECV-- 930
Query: 729 VSGLTPAAHYQLRITAHNNAGHA 751
V LT Y ++ A N+AG +
Sbjct: 931 VRNLTEGEEYTFQVMAVNSAGRS 953
Score = 82.2 bits (194), Expect = 9e-15
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHG-DWEEL-QVEAGTSE 628
VP PP +VD DS+ L W+D + GGSPI GY + +K + W+ + +
Sbjct: 82 VPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRD 141
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTG---LPCDIVHAYTKGTVPVKPKHSQMITLNTTTVT 685
+ L G Y+ + A N G G LP + V A P KP+ IT N+ T+
Sbjct: 142 FKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVIN-ITRNSVTL- 199
Query: 686 VWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAH 745
+W + DGG + +++E R++ W + +N V E F+V+ L Y+ RI A
Sbjct: 200 IWTEPKYDGGHKLTGYIVEKRDLPSKSW-MKANHVNVPECAFTVTDLVEGGKYEFRIRAK 258
Query: 746 NNAG 749
N AG
Sbjct: 259 NTAG 262
Score = 65.7 bits (153), Expect = 9e-10
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 27/307 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGS 126
VP P + + + + ++WT P G SPI +YI++ +E W + +
Sbjct: 379 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 438
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
V + +Q Y R+ A N G+ EP Q V + P GPP+ V +
Sbjct: 439 VATKLIQG----NEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNT 494
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
V+W+ P D I GY+V +E S V P + R
Sbjct: 495 ATVSWKRPVDD-GGSEITGYHVERREKKSLRWVRAIKTP--------------VSDLRCK 539
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV--PSLPPGALQCNALSSQSVRVS 303
++GLQ+ + Y V A N M+D P PP + +S ++
Sbjct: 540 VTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 599
Query: 304 WEPPPMRGRNGI-LQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W P + G G+ + GY V + V D +D + + L+ Y+ + A
Sbjct: 600 WGKPHIDG--GLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 657
Query: 363 FTAAGDG 369
AG G
Sbjct: 658 INDAGVG 664
Score = 56.8 bits (131), Expect = 4e-07
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP+ P ++D + ++ ++WT P G SPI Y +++KE K P +
Sbjct: 82 VPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANK--TPIRM 139
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEV-PSGPPQDVRVEAKSSTE 185
V L Y R++A N G +PS P + V + + P G P+ + + S T
Sbjct: 140 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT- 198
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNS 216
+ W P+ D + GY V ++L S S
Sbjct: 199 --LIWTEPKYD-GGHKLTGYIVEKRDLPSKS 226
Score = 56.8 bits (131), Expect = 4e-07
Identities = 40/151 (26%), Positives = 62/151 (41%), Gaps = 6/151 (3%)
Query: 76 IRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
+R D ++ + W P G S I NYIV+ +EA ST + V
Sbjct: 781 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYST---ATTKCHKCTYKVTG 837
Query: 135 LQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQ 194
L Y R++AEN G EP++ + E PS PP + + + + + + W P+
Sbjct: 838 LSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPS-PPDSLNIMDITKSTVSLAWPKPK 896
Query: 195 RDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
D I GY + Q S+ I + G
Sbjct: 897 HD-GGSKITGYVIEAQRKGSDQWTHITTVKG 926
Score = 56.0 bits (129), Expect = 7e-07
Identities = 70/327 (21%), Positives = 115/327 (35%), Gaps = 14/327 (4%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P L+ ++ SV + W+ P + G + I Y V T + T +
Sbjct: 777 PSPQLRPTDITKDSVTLHWDLPLIDGGSRITN-YIVEKREATR--KSYSTATTKCHKCTY 833
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
++GL Y V A G G + PS P + +++ + ++W
Sbjct: 834 KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWP 893
Query: 406 PPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
P G + GY + G ++ TH + T Q S
Sbjct: 894 KPKHDGGSKITGYVIEAQ--RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAG 951
Query: 465 LGEGEATRVVTVLPSDSVPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGV 522
+R V V +P + + ++ +NI + +G P P TW
Sbjct: 952 RSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 1011
Query: 523 GLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPI- 578
L+ T R N + T L I+ +DSG Y + NI G T++V P PP
Sbjct: 1012 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 1071
Query: 579 -LAVVDSYADSLHLQWS-DQGDGGSPI 603
+ + +D + W + DGG PI
Sbjct: 1072 PIKFDEVSSDFVTFSWDPPENDGGVPI 1098
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 10/131 (7%)
Query: 88 ISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+ W P G S I NYI++ +++ + W + V T+ V L Y R+
Sbjct: 2 LKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV----QKTTFRVTRLHEGMEYTFRV 57
Query: 146 IAENRLGQSE--PSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
AEN+ G E S+P+ +VP PP V+ + + + +TW P++ I
Sbjct: 58 SAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDS-VSLTWTDPKK-TGGSPIT 115
Query: 204 GYYVGFQELNS 214
GY++ F+E NS
Sbjct: 116 GYHLEFKERNS 126
Score = 49.6 bits (113), Expect = 6e-05
Identities = 39/106 (36%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 556 ENIHGRDEVTYTVE-VKVP--PQPP-ILAVVDSYADSLHLQW-SDQGDGGSPILGYVINY 610
EN +G E T T E VK P PP L ++D ++ L W + DGGS I GYVI
Sbjct: 851 ENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEA 910
Query: 611 KREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+R+ D W + G E V+ NL G Y + A N G P
Sbjct: 911 QRKGSDQWTHITTVKGL-ECVVRNLTEGEEYTFQVMAVNSAGRSAP 955
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQ-YKEAPESWPSTPQKVIVPG 125
+ P P ++ ++D T+ ++W +P + G S I Y+++ ++ + W V G
Sbjct: 870 EAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI---TTVKG 926
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP--SQPVQVTTTEEVP 169
V+NL Y +++A N G+S P S+PV V +P
Sbjct: 927 --LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLP 970
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 103 bits (246), Expect = 5e-21
Identities = 92/353 (26%), Positives = 153/353 (43%), Gaps = 32/353 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADS----QITTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYK--DGEHGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
G A + T + + + +KA + + +L+SW P + N + LY
Sbjct: 593 LGASTAEISARTMQSMFAKNFHVKAVM--KTSVLLSWEIPENYNSAMPFKILY 643
Score = 100 bits (239), Expect = 3e-20
Identities = 87/322 (27%), Positives = 136/322 (42%), Gaps = 28/322 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR 485
G G +T ++ S+ A+
Sbjct: 590 PQGLGASTAEISARTMQSMFAK 611
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG ++ S+ ++W+ G + Y + + P N + + K+I G+ T
Sbjct: 325 PPGTPVVTESTATSITLTWDS----GNPEPVSYYIIQHKPK-----NSEELYKEIDGVAT 375
Query: 346 T---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKIL 401
T ++GL Y++Y V A G G + PV T E PS AP D++A + S IL
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
V W P PNG + GY +Y ++ K ++ S ++ P+ T+ V A
Sbjct: 436 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLA 494
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSF 489
T +G+G + + V+ VP + +F
Sbjct: 495 FTSIGDGPLSSDIQVITQTGVPGQPLNF 522
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 66.1 bits (154), Expect = 7e-10
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRD 196
++++W PP+ D
Sbjct: 531 SILLSWTPPRSD 542
Score = 46.8 bits (106), Expect = 4e-04
Identities = 79/353 (22%), Positives = 135/353 (38%), Gaps = 28/353 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVW 687
+ Y + A + G G + A T ++ K H + + + T+ + W
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAV-MKTSVLLSW 627
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 103 bits (246), Expect = 5e-21
Identities = 92/353 (26%), Positives = 153/353 (43%), Gaps = 32/353 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 322 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 375
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 436 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADS----QITTIG 480
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 481 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 539
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 540 ----RSDTIANYELVYK--DGEHGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 592
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
G A + T + + + +KA + + +L+SW P + N + LY
Sbjct: 593 LGASTAEISARTMQSMFAKNFHVKAVM--KTSVLLSWEIPENYNSAMPFKILY 643
Score = 100 bits (239), Expect = 3e-20
Identities = 87/322 (27%), Positives = 136/322 (42%), Gaps = 28/322 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 318 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 359
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 360 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 417
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 418 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 475
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 476 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 535
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 536 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 589
Query: 464 RLGEGEATRVVTVLPSDSVPAR 485
G G +T ++ S+ A+
Sbjct: 590 PQGLGASTAEISARTMQSMFAK 611
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG ++ S+ ++W+ G + Y + + P N + + K+I G+ T
Sbjct: 325 PPGTPVVTESTATSITLTWDS----GNPEPVSYYIIQHKPK-----NSEELYKEIDGVAT 375
Query: 346 T---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKIL 401
T ++GL Y++Y V A G G + PV T E PS AP D++A + S IL
Sbjct: 376 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
V W P PNG + GY +Y ++ K ++ S ++ P+ T+ V A
Sbjct: 436 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLA 494
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSF 489
T +G+G + + V+ VP + +F
Sbjct: 495 FTSIGDGPLSSDIQVITQTGVPGQPLNF 522
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 252 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 308
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 309 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 364
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 365 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 424
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 425 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 483
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 484 PQKTYSVKVLAFTSIG 499
Score = 66.1 bits (154), Expect = 7e-10
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 473 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 530
Query: 185 ELIVTWEPPQRD 196
++++W PP+ D
Sbjct: 531 SILLSWTPPRSD 542
Score = 46.8 bits (106), Expect = 4e-04
Identities = 79/353 (22%), Positives = 135/353 (38%), Gaps = 28/353 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 291 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 343
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 344 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 400
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 401 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 459
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 518
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 519 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 575
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVW 687
+ Y + A + G G + A T ++ K H + + + T+ + W
Sbjct: 576 KPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAV-MKTSVLLSW 627
Score = 32.3 bits (70), Expect = 9.9
Identities = 32/125 (25%), Positives = 43/125 (34%), Gaps = 15/125 (12%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCSV 555
G P P TW T N G LR G L I ++ +D G Y C
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 556 ENIHG 560
N G
Sbjct: 210 TNSAG 214
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 103 bits (246), Expect = 5e-21
Identities = 92/353 (26%), Positives = 153/353 (43%), Gaps = 32/353 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 312 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 365
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 366 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 425
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 426 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADS----QITTIG 470
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 471 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 529
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 530 ----RSDTIANYELVYK--DGEHGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 582
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
G A + T + + + +KA + + +L+SW P + N + LY
Sbjct: 583 LGASTAEISARTMQSMFAKNFHVKAVM--KTSVLLSWEIPENYNSAMPFKILY 633
Score = 100 bits (239), Expect = 3e-20
Identities = 87/322 (27%), Positives = 136/322 (42%), Gaps = 28/322 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 308 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 349
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 350 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 407
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 408 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 465
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 466 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 525
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 526 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 579
Query: 464 RLGEGEATRVVTVLPSDSVPAR 485
G G +T ++ S+ A+
Sbjct: 580 PQGLGASTAEISARTMQSMFAK 601
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG ++ S+ ++W+ G + Y + + P N + + K+I G+ T
Sbjct: 315 PPGTPVVTESTATSITLTWDS----GNPEPVSYYIIQHKPK-----NSEELYKEIDGVAT 365
Query: 346 T---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKIL 401
T ++GL Y++Y V A G G + PV T E PS AP D++A + S IL
Sbjct: 366 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 425
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
V W P PNG + GY +Y ++ K ++ S ++ P+ T+ V A
Sbjct: 426 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLA 484
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSF 489
T +G+G + + V+ VP + +F
Sbjct: 485 FTSIGDGPLSSDIQVITQTGVPGQPLNF 512
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 242 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 298
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 299 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 354
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 355 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 414
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 415 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 473
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 474 PQKTYSVKVLAFTSIG 489
Score = 66.1 bits (154), Expect = 7e-10
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 403 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 462
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 463 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 520
Query: 185 ELIVTWEPPQRD 196
++++W PP+ D
Sbjct: 521 SILLSWTPPRSD 532
Score = 51.2 bits (117), Expect = 2e-05
Identities = 73/314 (23%), Positives = 117/314 (37%), Gaps = 28/314 (8%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
G P P TW T N G LR S G L I ++ +D G Y C N
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSE--SIGALQIEQSEESDQGKYECVATNSA 207
Query: 560 G-RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGS-PILGYVINYKREHGDW 617
G R + V+V PP ++ + + + GGS I + + W
Sbjct: 208 GTRYSAPANLYVRVRRVPPRFSIPPTNHEIM--------PGGSVNITCVAVGSPMPYVKW 259
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL-PCDIVHAYTKGTVPVKPKHSQM 676
L E T E +P + N + ++ A + TV PK
Sbjct: 260 -MLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGT 318
Query: 677 ITLNTTTVTVWLDSWGDGGC-GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
+ +T T +W G + Y++I+++ + + + V T +SV+GL+P
Sbjct: 319 PVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTR--YSVAGLSPY 376
Query: 736 AHYQLRITAHNNAG 749
+ Y+ R+ A NN G
Sbjct: 377 SDYEFRVVAVNNIG 390
Score = 46.8 bits (106), Expect = 4e-04
Identities = 79/353 (22%), Positives = 135/353 (38%), Gaps = 28/353 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 281 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 333
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 334 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 390
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 391 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 449
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 450 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 508
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 509 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 565
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVW 687
+ Y + A + G G + A T ++ K H + + + T+ + W
Sbjct: 566 KPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAV-MKTSVLLSW 617
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 103 bits (246), Expect = 5e-21
Identities = 92/353 (26%), Positives = 153/353 (43%), Gaps = 32/353 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 295 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 348
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 349 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 408
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 409 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADS----QITTIG 453
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 454 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 512
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 513 ----RSDTIANYELVYK--DGEHGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 565
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
G A + T + + + +KA + + +L+SW P + N + LY
Sbjct: 566 LGASTAEISARTMQSMFAKNFHVKAVM--KTSVLLSWEIPENYNSAMPFKILY 616
Score = 100 bits (239), Expect = 3e-20
Identities = 87/322 (27%), Positives = 136/322 (42%), Gaps = 28/322 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 291 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 332
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 333 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 390
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 391 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 448
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 449 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 508
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 509 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 562
Query: 464 RLGEGEATRVVTVLPSDSVPAR 485
G G +T ++ S+ A+
Sbjct: 563 PQGLGASTAEISARTMQSMFAK 584
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG ++ S+ ++W+ G + Y + + P N + + K+I G+ T
Sbjct: 298 PPGTPVVTESTATSITLTWDS----GNPEPVSYYIIQHKPK-----NSEELYKEIDGVAT 348
Query: 346 T---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKIL 401
T ++GL Y++Y V A G G + PV T E PS AP D++A + S IL
Sbjct: 349 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 408
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
V W P PNG + GY +Y ++ K ++ S ++ P+ T+ V A
Sbjct: 409 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLA 467
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSF 489
T +G+G + + V+ VP + +F
Sbjct: 468 FTSIGDGPLSSDIQVITQTGVPGQPLNF 495
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 225 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 281
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 282 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 337
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 338 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 397
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 398 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 456
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 457 PQKTYSVKVLAFTSIG 472
Score = 66.1 bits (154), Expect = 7e-10
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 386 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 445
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 446 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 503
Query: 185 ELIVTWEPPQRD 196
++++W PP+ D
Sbjct: 504 SILLSWTPPRSD 515
Score = 46.8 bits (106), Expect = 4e-04
Identities = 79/353 (22%), Positives = 135/353 (38%), Gaps = 28/353 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 264 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 316
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 317 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 373
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 374 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 432
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 433 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 491
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 492 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 548
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVW 687
+ Y + A + G G + A T ++ K H + + + T+ + W
Sbjct: 549 KPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAV-MKTSVLLSW 600
Score = 34.7 bits (76), Expect = 1.8
Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 12/122 (9%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 66 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 125
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSS-DGTLTISMTQSADSGNYTCSVENI 558
G P P TW T N G LR + G L I ++ +D G Y C N
Sbjct: 126 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNS 185
Query: 559 HG 560
G
Sbjct: 186 AG 187
>AK074077-1|BAB84903.1| 572|Homo sapiens FLJ00148 protein protein.
Length = 572
Score = 102 bits (244), Expect = 8e-21
Identities = 94/365 (25%), Positives = 151/365 (41%), Gaps = 30/365 (8%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T + +L+ Y + + A N +G+S S PV+V E P+ PQ+V+V ++++L
Sbjct: 19 TMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLE 78
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
VTW+PP + NGNI GY + + E +S + ++ L
Sbjct: 79 VTWDPPPPESQNGNIQGYKIYYWEADSQN-------------ETEKMKVLFLPEPVVRLK 125
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L H Y V + A+N+ + P P L + ++S ++ VSW P
Sbjct: 126 NLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG-APSFLAFSEITSTTLNVSWGEP 184
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---LHTTLSGLRRYTNYSVTVCAFT 364
NGILQGYRV Y P+ G VT ++ G + L + Y V A T
Sbjct: 185 --AAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQART 242
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
A + E P +P D+ S +++ + W S + GY +
Sbjct: 243 ITYGPELQANITAGPAEGSPGSPRDV-LVTKSASELTLQWTEGHSGDTPTTGYVIEARPS 301
Query: 425 EDGREEGTHK---RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
++G + K R + TLS + R T++F V A G GE + PS +
Sbjct: 302 DEGLWDMFVKDIPRSATSYTLSLDKLRQ--GVTYEFRVVAVNEAGYGEPSN-----PSTA 354
Query: 482 VPARI 486
V A++
Sbjct: 355 VSAQV 359
Score = 100 bits (239), Expect = 3e-20
Identities = 55/191 (28%), Positives = 92/191 (48%), Gaps = 1/191 (0%)
Query: 227 ASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP 286
A + +TV + T+ + L+ L+K+ Y V++ AYN E P++
Sbjct: 5 AQSSFKTVNSSSTS-TMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMA 63
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
P +Q L++ + V+W+PPP +NG +QGY++ Y E +
Sbjct: 64 PQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVR 123
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L L +T Y V++ AF AAGDG ++ P T + P AP+ + + + + VSW
Sbjct: 124 LKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGE 183
Query: 407 PSSPNGVLVGY 417
P++ NG+L GY
Sbjct: 184 PAAANGILQGY 194
Score = 56.0 bits (129), Expect = 7e-07
Identities = 75/330 (22%), Positives = 128/330 (38%), Gaps = 25/330 (7%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSW- 404
L+ L++Y Y V + A+ G+ +APV E P+ AP +++ + +++ V+W
Sbjct: 23 LTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWD 82
Query: 405 -LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
PP S NG + GY +Y + E K + P + + + + +SA
Sbjct: 83 PPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS-HTKYLVSISAFN 141
Query: 464 RLGEGEAT--------RVVTVLPSDSVPARITSFSRNIV--TPWKENISLSCNKVGVPAP 513
G+G + + PS + ITS + N+ P N L +V V P
Sbjct: 142 AAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRV-VYEP 200
Query: 514 ATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV--- 570
+ GV T+ + L + + + I E+ +
Sbjct: 201 LAP--VQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPA 258
Query: 571 KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAG 625
+ P P +V A L LQW++ G +P GYVI + + G W+ ++ A
Sbjct: 259 EGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSAT 318
Query: 626 TSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
+ L L G Y+ + A N G G P
Sbjct: 319 SYTLSLDKLRQGVTYEFRVVAVNEAGYGEP 348
Score = 54.4 bits (125), Expect = 2e-06
Identities = 76/309 (24%), Positives = 113/309 (36%), Gaps = 28/309 (9%)
Query: 73 PKNIRVIDQQSRTIQISWTQP--YAGNSPIINYIVQYKEAPESWPSTPQKVI-VPGSVTS 129
P+N++V + ++++W P + N I Y + Y EA + KV+ +P V
Sbjct: 64 PQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVR 123
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++NL T Y + I A N G S P Q T + P G P + +ST L V+
Sbjct: 124 --LKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVS 180
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P NG + GY V ++ L P V TVE G + + L
Sbjct: 181 WGEPAAA--NGILQGYRVVYEPL----------APVQGVSKVVTVEVRGNWQRWLKVRDL 228
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
K Y VQA E P P L S+ + + W
Sbjct: 229 TKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTK--SASELTLQW----T 282
Query: 310 RGRNG--ILQGYRVTYAPVTD--WYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
G +G GY + P + W + + + +L LR+ Y V A
Sbjct: 283 EGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNE 342
Query: 366 AGDGVRAAP 374
AG G + P
Sbjct: 343 AGYGEPSNP 351
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVT 128
P P+++ V S + + WT+ ++G++P Y+++ + + E W + + P S T
Sbjct: 262 PGSPRDVLVTKSASE-LTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDI--PRSAT 318
Query: 129 S--ASVQNLQPATSYHLRIIAENRLGQSEPSQP-VQVTTTEEVP 169
S S+ L+ +Y R++A N G EPS P V+ E P
Sbjct: 319 SYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP 362
Score = 42.7 bits (96), Expect = 0.007
Identities = 64/235 (27%), Positives = 94/235 (40%), Gaps = 24/235 (10%)
Query: 530 KNVSSDGTLTI-SMTQSADSGNYTC--SVENIHGRDEVTYTVEVKVPPQPPILA-----V 581
K V+S T T+ +T Y + NI G + VEV V P +A V
Sbjct: 10 KTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQV 69
Query: 582 VDSYADSLHLQWSD---QGDGGSPILGYVINYKR--EHGDWEELQVEAGTSEHV-LPNLW 635
A L + W + G+ I GY I Y + E+++V V L NL
Sbjct: 70 TPLTASQLEVTWDPPPPESQNGN-IQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLT 128
Query: 636 CGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGG 695
T+Y + I+AFN G G D T P P + +TT+ V SWG+
Sbjct: 129 SHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNV---SWGEPA 185
Query: 696 C--GILY-FVIEYREMSQPQW--RLVSNSVQAT-ERVFSVSGLTPAAHYQLRITA 744
GIL + + Y ++ Q ++V+ V+ +R V LT Y R+ A
Sbjct: 186 AANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 240
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 101 bits (241), Expect = 2e-20
Identities = 97/335 (28%), Positives = 146/335 (43%), Gaps = 43/335 (12%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V + + P P V ++T + +TW D N + + Y
Sbjct: 299 VAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW-----DSGNPDPVSY 349
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
YV E S S GP Y ++ E T +R ++ GL ++ Y + V A NS
Sbjct: 350 YV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNSEYEIWVSAVNSI 395
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA- 324
E P+ P +Q LS+ ++ V WE P NG+++GYRV Y
Sbjct: 396 GQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP--NGLIRGYRVYYTM 453
Query: 325 ----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
PV +W N D L TT+ L Y+V V AFT+ GDG + P+ T
Sbjct: 454 EPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 507
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
++ VP P +++A S I +SW PP + ++ Y L + GRE G R P
Sbjct: 508 QQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGREVG---RTFDP 562
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVV 474
+T S+ P + F ++A + G G T VV
Sbjct: 563 TT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 596
Score = 88.6 bits (210), Expect = 1e-16
Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 32/344 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 318 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 371
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ P++V+ S+T +I
Sbjct: 372 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 431
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 432 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 476
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 477 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 535
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R + Y + + +G E T + + + L+ T Y+ + A + G
Sbjct: 536 ----RQESIIKYELLFREGD--HGREVGRTFDPTTSY-VVEDLKPNTEYAFRLAARSPQG 588
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
G V T + + +P + K + + +L+SW P + N
Sbjct: 589 LGAFTPVVRQRTLQSI--SPKNFKVKMIMKTSVLLSWEFPDNYN 630
Score = 80.2 bits (189), Expect = 4e-14
Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 10/254 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N++++C VG P P W G E ++ G + +T DS NYTC +
Sbjct: 248 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSL 304
Query: 560 GRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 305 GVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGN-PDPVSYYVIEYKSKSQDGP 362
Query: 619 -ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQM 676
+++ + T+ + + L + Y+++++A N IG G P + V T P P++ Q
Sbjct: 363 YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQA 422
Query: 677 ITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 423 RMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLED 481
Query: 736 AHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 482 ETYTVRVLAFTSVG 495
Score = 52.0 bits (119), Expect = 1e-05
Identities = 73/310 (23%), Positives = 124/310 (40%), Gaps = 23/310 (7%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + + A +GE +TVL D +P+ + V ++ C
Sbjct: 99 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 158
Query: 508 VGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG---R 561
G P P TW + + ++ S R G L I ++ D G Y C N G
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 562 DEVTYTVEV-KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL 620
V V +V P+ IL + ++ + GSP + YV + E
Sbjct: 219 SPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVA-VGSP-MPYVKWMQGAEDLTPED 276
Query: 621 QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ G + L ++ Y A + +G + V T ++P P + M+T N
Sbjct: 277 DMPVGRNVLELTDVKDSANYT--CVAMSSLGV---IEAVAQITVKSLPKAP-GTPMVTEN 330
Query: 681 T-TTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
T T++T+ DS + Y+VIEY+ SQ + + T +S+ GL+P + Y+
Sbjct: 331 TATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTTR--YSIGGLSPNSEYE 386
Query: 740 LRITAHNNAG 749
+ ++A N+ G
Sbjct: 387 IWVSAVNSIG 396
Score = 43.2 bits (97), Expect = 0.005
Identities = 70/324 (21%), Positives = 129/324 (39%), Gaps = 29/324 (8%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLS 438
T + +P AP ++ I ++W S N V Y Y+ + ++G ++
Sbjct: 314 TVKSLPKAPGTPMVTENTATSITITW---DSGNPDPVSY--YVIEYKSKSQDGPYQIKED 368
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP--------ARITSFS 490
+T + P + ++ WVSA +G+G + V + P AR+ S +
Sbjct: 369 ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLS-A 427
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++ W+E + + G T + VG + + NV D +L ++ +
Sbjct: 428 TTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVG--NWQKHNV--DDSLLTTVGSLLEDET 483
Query: 551 YTCSVENIH--GRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL 604
YT V G ++ ++VK VP QP L S+ L WS I+
Sbjct: 484 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ--ESII 541
Query: 605 GYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + ++ +HG E + T+ +V+ +L T Y + A + G G +V T
Sbjct: 542 KYELLFREGDHGR-EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 600
Query: 664 KGTVPVKPKHSQMITLNTTTVTVW 687
++ K +MI + T+ + W
Sbjct: 601 LQSISPKNFKVKMI-MKTSVLLSW 623
>AK001694-1|BAA91841.1| 574|Homo sapiens protein ( Homo sapiens
cDNA FLJ10832 fis, clone NT2RP4001150, weakly similar to
NG-CAM RELATED CELL ADHESION MOLECULE PRECURSOR. ).
Length = 574
Score = 101 bits (241), Expect = 2e-20
Identities = 64/211 (30%), Positives = 98/211 (46%), Gaps = 12/211 (5%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
E VP+ P + + ++ + V+WEPPP+ +NG +QGY++ + W +T++
Sbjct: 22 EAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF-----WEAQRGNLTER 76
Query: 340 ISGLHTT-----LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV 394
+ L L L YT Y V+V AF AAGDG R+ P T++ PSAP+ +K +
Sbjct: 77 VKTLFPAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSE 136
Query: 395 SSRNKILVSWLPPSSPNGVLVGYTLYMSVIE--DGREEGTHKRMLSPSTLSHETSRSPPR 452
+ + VSW P PNG+L GY L DG + + S L +
Sbjct: 137 LTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEG 196
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
T++F + A T E VT P + P
Sbjct: 197 VTYRFRIRAKTFTYGPEIEANVTTGPGEGAP 227
Score = 99 bits (238), Expect = 4e-20
Identities = 95/343 (27%), Positives = 142/343 (41%), Gaps = 30/343 (8%)
Query: 149 NRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVG 208
N +G+ S P +V E VP+ P++V V ++T+L VTWEPP D NG+I GY +
Sbjct: 5 NAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIY 64
Query: 209 FQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXX 268
F E G + V+T+ A + L L + AY V V A+N+
Sbjct: 65 FWEAQR----------GNLTERVKTL---FPAENSVKLKNLTGYTAYMVSVAAFNAAGDG 111
Query: 269 XXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD 328
+ PS P +++ + L++ SV VSWE P NGIL+GYR+ Y P +
Sbjct: 112 PRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNVSWEAPQF--PNGILEGYRLVYEPCSP 168
Query: 329 WYGNEDAVTKQISG---LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS 385
G VT + G L + L Y + A T A V E P
Sbjct: 169 VDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPG 228
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK---RMLSPSTL 442
P + V + I + W G + Y + ++G + K + +S T
Sbjct: 229 PPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTF 287
Query: 443 SHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR 485
S + + P ++ F V A G G + PS SVPA+
Sbjct: 288 SMDILK--PGVSYDFRVIAVNDYGFGTPSS-----PSQSVPAQ 323
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 6/140 (4%)
Query: 73 PKNIRVIDQQSRTIQISWTQPY--AGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
P+N+ V + + ++W P + N I Y + + EA + K + P S
Sbjct: 29 PRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFPAE-NSV 87
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NL T+Y + + A N G S P Q T + PS P V+ ++T + V+W
Sbjct: 88 KLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSA-PSSVKFSELTTTSVNVSW 146
Query: 191 EPPQRDLWNGNILGYYVGFQ 210
E PQ NG + GY + ++
Sbjct: 147 EAPQ--FPNGILEGYRLVYE 164
Score = 51.2 bits (117), Expect = 2e-05
Identities = 65/311 (20%), Positives = 120/311 (38%), Gaps = 19/311 (6%)
Query: 363 FTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP--SSPNGVLVGYTL 419
+ A G+G + P E VP+A P ++ ++ ++ V+W PP S NG + GY +
Sbjct: 4 YNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 63
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
Y + G K + P+ S + + V+A G+G +
Sbjct: 64 YFWEAQRGNLTERVKTLF-PAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQ 122
Query: 480 DSVPARITSFSRNIVTPWKENISLSC----NKVGVPAPATTWTMNGV-GLESTLRKNVSS 534
+ P+ +S + +T N+S N + + V G+ + +V
Sbjct: 123 QAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKG 182
Query: 535 DGTLTISMTQSADSGNYTCSVEN---IHGRD-EVTYTVEV-KVPPQPPILAVVDSYADSL 589
+ L + + A+ Y + +G + E T + P PP + ++ Y+ ++
Sbjct: 183 NSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAI 242
Query: 590 HLQWSDQGDGGSPILGYVINYK-REHGDWE----ELQVEAGTSEHVLPNLWCGTRYQLYI 644
+ WS G PI YVI + + G W+ ++ E + + L G Y +
Sbjct: 243 AIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV 302
Query: 645 TAFNRIGTGLP 655
A N G G P
Sbjct: 303 IAVNDYGFGTP 313
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSAS 131
P + +I + S I I W+ G PI Y+++ + + E W + + S + S
Sbjct: 229 PPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFS 288
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
+ L+P SY R+IA N G PS P Q
Sbjct: 289 MDILKPGVSYDFRVIAVNDYGFGTPSSPSQ 318
>AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS
protein.
Length = 475
Score = 101 bits (241), Expect = 2e-20
Identities = 97/335 (28%), Positives = 146/335 (43%), Gaps = 43/335 (12%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V + + P P V ++T + +TW D N + + Y
Sbjct: 173 VAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW-----DSGNPDPVSY 223
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
YV E S S GP Y ++ E T +R ++ GL ++ Y + V A NS
Sbjct: 224 YV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNSEYEIWVSAVNSI 269
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA- 324
E P+ P +Q LS+ ++ V WE P NG+++GYRV Y
Sbjct: 270 GQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP--NGLIRGYRVYYTM 327
Query: 325 ----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
PV +W N D L TT+ L Y+V V AFT+ GDG + P+ T
Sbjct: 328 EPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 381
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
++ VP P +++A S I +SW PP + ++ Y L + GRE G R P
Sbjct: 382 QQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGREVG---RTFDP 436
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVV 474
+T S+ P + F ++A + G G T VV
Sbjct: 437 TT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 470
Score = 83.0 bits (196), Expect = 5e-15
Identities = 66/240 (27%), Positives = 107/240 (44%), Gaps = 23/240 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 192 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 245
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ P++V+ S+T +I
Sbjct: 246 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 305
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 306 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 350
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 351 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 409
Score = 80.2 bits (189), Expect = 4e-14
Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 10/254 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N++++C VG P P W G E ++ G + +T DS NYTC +
Sbjct: 122 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSL 178
Query: 560 GRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 179 GVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGN-PDPVSYYVIEYKSKSQDGP 236
Query: 619 -ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQM 676
+++ + T+ + + L + Y+++++A N IG G P + V T P P++ Q
Sbjct: 237 YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQA 296
Query: 677 ITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 297 RMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLED 355
Query: 736 AHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 356 ETYTVRVLAFTSVG 369
Score = 71.7 bits (168), Expect = 1e-11
Identities = 43/139 (30%), Positives = 74/139 (53%), Gaps = 6/139 (4%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+N++ + T+ + W +P N I Y V Y PE QK V S+ + +V
Sbjct: 291 PRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLT-TV 349
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+L +Y +R++A +G S P+QV T + VP G P ++R EA+S T + ++W P
Sbjct: 350 GSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVP-GQPMNLRAEARSETSITLSWSP 408
Query: 193 PQRDLWNGNILGYYVGFQE 211
P+++ +I+ Y + F+E
Sbjct: 409 PRQE----SIIKYELLFRE 423
Score = 39.1 bits (87), Expect = 0.086
Identities = 65/300 (21%), Positives = 118/300 (39%), Gaps = 28/300 (9%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLS 438
T + +P AP ++ I ++W S N V Y Y+ + ++G ++
Sbjct: 188 TVKSLPKAPGTPMVTENTATSITITW---DSGNPDPVSY--YVIEYKSKSQDGPYQIKED 242
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP--------ARITSFS 490
+T + P + ++ WVSA +G+G + V + P AR+ S +
Sbjct: 243 ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLS-A 301
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++ W+E + + G T + VG + + NV D +L ++ +
Sbjct: 302 TTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVG--NWQKHNV--DDSLLTTVGSLLEDET 357
Query: 551 YTCSVENIH--GRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL 604
YT V G ++ ++VK VP QP L S+ L WS I+
Sbjct: 358 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ--ESII 415
Query: 605 GYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + ++ +HG E + T+ +V+ +L T Y + A + G G +V T
Sbjct: 416 KYELLFREGDHGR-EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 474
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P N+R + +I +SW+ P II Y + ++E + P T
Sbjct: 385 VPGQPMNLRAEARSETSITLSWSPP--RQESIIKYELLFREGDHG--REVGRTFDP--TT 438
Query: 129 SASVQNLQPATSYHLRIIAENRLG 152
S V++L+P T Y R+ A + G
Sbjct: 439 SYVVEDLKPNTEYAFRLAARSPQG 462
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 101 bits (241), Expect = 2e-20
Identities = 97/335 (28%), Positives = 146/335 (43%), Gaps = 43/335 (12%)
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
+A + LG E + V + + P P V ++T + +TW D N + + Y
Sbjct: 325 VAMSSLGVIEAVAQITVKSLPKAPGTP----MVTENTATSITITW-----DSGNPDPVSY 375
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSR 265
YV E S S GP Y ++ E T +R ++ GL ++ Y + V A NS
Sbjct: 376 YV--IEYKSKSQ----DGP----YQIK--EDITT--TRYSIGGLSPNSEYEIWVSAVNSI 421
Query: 266 XXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYA- 324
E P+ P +Q LS+ ++ V WE P NG+++GYRV Y
Sbjct: 422 GQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP--NGLIRGYRVYYTM 479
Query: 325 ----PVTDWYG-NEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
PV +W N D L TT+ L Y+V V AFT+ GDG + P+ T
Sbjct: 480 EPEHPVGNWQKHNVD------DSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 533
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
++ VP P +++A S I +SW PP + ++ Y L + GRE G R P
Sbjct: 534 QQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGREVG---RTFDP 588
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVV 474
+T S+ P + F ++A + G G T VV
Sbjct: 589 TT-SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 622
Score = 88.6 bits (210), Expect = 1e-16
Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 32/344 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I I+W +GN P+ Y+++YK + P ++ I +
Sbjct: 344 LPKAPGTPMVTENTATSITITWD---SGNPDPVSYYVIEYKSKSQDGPYQIKEDI---TT 397
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T S+ L P + Y + + A N +GQ PS+ V T E+ P+ P++V+ S+T +I
Sbjct: 398 TRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMI 457
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V WE P NG I GY V + + P G ++ V+ + TT+
Sbjct: 458 VQWEEPVEP--NGLIRGYRVYY--------TMEPEHPVG-NWQKHNVDDS----LLTTVG 502
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L + Y V V A+ S + VP P L+ A S S+ +SW PP
Sbjct: 503 SLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMN-LRAEARSETSITLSWSPP 561
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R + Y + + +G E T + + + L+ T Y+ + A + G
Sbjct: 562 ----RQESIIKYELLFREGD--HGREVGRTFDPTTSY-VVEDLKPNTEYAFRLAARSPQG 614
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
G V T + + +P + K + + +L+SW P + N
Sbjct: 615 LGAFTPVVRQRTLQSI--SPKNFKVKMIMKTSVLLSWEFPDNYN 656
Score = 80.2 bits (189), Expect = 4e-14
Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 10/254 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
N++++C VG P P W G E ++ G + +T DS NYTC +
Sbjct: 274 NVNITCVAVGSPMPYVKWMQ---GAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSL 330
Query: 560 GRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK +P P V ++ A S+ + W D G+ P+ YVI YK + D
Sbjct: 331 GVIEAVAQITVKSLPKAPGTPMVTENTATSITITW-DSGN-PDPVSYYVIEYKSKSQDGP 388
Query: 619 -ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHSQM 676
+++ + T+ + + L + Y+++++A N IG G P + V T P P++ Q
Sbjct: 389 YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQA 448
Query: 677 ITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA 735
L+ TT+ V W + G Y V E P ++V + +V L
Sbjct: 449 RMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVD-DSLLTTVGSLLED 507
Query: 736 AHYQLRITAHNNAG 749
Y +R+ A + G
Sbjct: 508 ETYTVRVLAFTSVG 521
Score = 52.0 bits (119), Expect = 1e-05
Identities = 73/310 (23%), Positives = 124/310 (40%), Gaps = 23/310 (7%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + + A +GE +TVL D +P+ + V ++ C
Sbjct: 125 PRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAA 184
Query: 508 VGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG---R 561
G P P TW + + ++ S R G L I ++ D G Y C N G
Sbjct: 185 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 244
Query: 562 DEVTYTVEV-KVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL 620
V V +V P+ IL + ++ + GSP + YV + E
Sbjct: 245 SPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVA-VGSP-MPYVKWMQGAEDLTPED 302
Query: 621 QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ G + L ++ Y A + +G + V T ++P P + M+T N
Sbjct: 303 DMPVGRNVLELTDVKDSANYT--CVAMSSLGV---IEAVAQITVKSLPKAP-GTPMVTEN 356
Query: 681 T-TTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
T T++T+ DS + Y+VIEY+ SQ + + T +S+ GL+P + Y+
Sbjct: 357 TATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTTR--YSIGGLSPNSEYE 412
Query: 740 LRITAHNNAG 749
+ ++A N+ G
Sbjct: 413 IWVSAVNSIG 422
Score = 43.2 bits (97), Expect = 0.005
Identities = 70/324 (21%), Positives = 129/324 (39%), Gaps = 29/324 (8%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLS 438
T + +P AP ++ I ++W S N V Y Y+ + ++G ++
Sbjct: 340 TVKSLPKAPGTPMVTENTATSITITW---DSGNPDPVSY--YVIEYKSKSQDGPYQIKED 394
Query: 439 PSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP--------ARITSFS 490
+T + P + ++ WVSA +G+G + V + P AR+ S +
Sbjct: 395 ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLS-A 453
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++ W+E + + G T + VG + + NV D +L ++ +
Sbjct: 454 TTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVG--NWQKHNV--DDSLLTTVGSLLEDET 509
Query: 551 YTCSVENIH--GRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL 604
YT V G ++ ++VK VP QP L S+ L WS I+
Sbjct: 510 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ--ESII 567
Query: 605 GYVINYKR-EHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y + ++ +HG E + T+ +V+ +L T Y + A + G G +V T
Sbjct: 568 KYELLFREGDHGR-EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 626
Query: 664 KGTVPVKPKHSQMITLNTTTVTVW 687
++ K +MI + T+ + W
Sbjct: 627 LQSISPKNFKVKMI-MKTSVLLSW 649
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 100 bits (239), Expect = 3e-20
Identities = 93/354 (26%), Positives = 153/354 (43%), Gaps = 33/354 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+P+ P V + + +I ++W +GN P+ YI+Q+K P++ K I +
Sbjct: 316 LPKPPGTPVVTESTATSITLTWD---SGNPEPVSYYIIQHK--PKNSEEL-YKEIDGVAT 369
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T SV L P + Y R++A N +G+ PS+PV T+E+ PS P+DV+ SST ++
Sbjct: 370 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 429
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V W+ P+ NG I GY V + ++ V ++ V + TT+
Sbjct: 430 VQWKEPEEP--NGQIQGYRV-YYTMDPTQHV--------NNWMKHNVADS----QITTIG 474
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L Y+V V A+ S VP P + S S+ +SW PP
Sbjct: 475 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN-FKAEPESETSILLSWTPP 533
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
R+ + Y + Y +G E +T + G L GL+ + Y + A + G
Sbjct: 534 ----RSDTIANYELVYK--DGEHGEEQRITIE-PGTSYRLQGLKPNSLYYFRLAARSPQG 586
Query: 368 DGVRAAPVYCHT-EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
G A + T + V + +KA + + +L+SW P + N + LY
Sbjct: 587 LGASTAEISARTMQSTVFAKNFHVKAVM--KTSVLLSWEIPENYNSAMPFKILY 638
Score = 99.1 bits (236), Expect = 8e-20
Identities = 85/312 (27%), Positives = 132/312 (42%), Gaps = 28/312 (8%)
Query: 164 TTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
T + +P P V E+ ++T + +TW D N + YY+ I
Sbjct: 312 TVKALPKPPGTPVVTES-TATSITLTW-----DSGNPEPVSYYI------------IQHK 353
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
P + + ++G T +R +++GL ++ Y V A N+ E P
Sbjct: 354 PKNSEELYKEIDGVAT--TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAP 411
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S P +Q LSS ++ V W+ P NG +QGYRV Y + N
Sbjct: 412 SSAPRDVQARMLSSTTILVQWKEP--EEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 469
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
TT+ L YSV V AFT+ GDG ++ + T+ VP P + KA S IL+S
Sbjct: 470 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLS 529
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
W PP S + Y L V +DG E G +R+ S+ P + + F ++A +
Sbjct: 530 WTPPRS--DTIANYEL---VYKDG-EHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARS 583
Query: 464 RLGEGEATRVVT 475
G G +T ++
Sbjct: 584 PQGLGASTAEIS 595
Score = 81.4 bits (192), Expect = 2e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 14/208 (6%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PPG ++ S+ ++W+ G + Y + + P N + + K+I G+ T
Sbjct: 319 PPGTPVVTESTATSITLTWDS----GNPEPVSYYIIQHKPK-----NSEELYKEIDGVAT 369
Query: 346 T---LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKIL 401
T ++GL Y++Y V A G G + PV T E PS AP D++A + S IL
Sbjct: 370 TRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 429
Query: 402 VSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSA 461
V W P PNG + GY +Y ++ K ++ S ++ P+ T+ V A
Sbjct: 430 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLA 488
Query: 462 STRLGEGEATRVVTVLPSDSVPARITSF 489
T +G+G + + V+ VP + +F
Sbjct: 489 FTSIGDGPLSSDIQVITQTGVPGQPLNF 516
Score = 77.0 bits (181), Expect = 3e-13
Identities = 68/256 (26%), Positives = 114/256 (44%), Gaps = 14/256 (5%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+++++C VG P P W + G E ++ G + + S NYTC +
Sbjct: 246 SVNITCVAVGSPMPYVKWML---GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTL 302
Query: 560 GRDEVTYTVEVKVPPQPPILAVV-DSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE 618
G E + VK P+PP VV +S A S+ L W D G+ P+ Y+I +K ++ E
Sbjct: 303 GVIEAIAQITVKALPKPPGTPVVTESTATSITLTW-DSGN-PEPVSYYIIQHKPKNS--E 358
Query: 619 ELQVE---AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVK-PKHS 674
EL E T+ + + L + Y+ + A N IG G P + V T P P+
Sbjct: 359 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 418
Query: 675 QMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLT 733
Q L++TT+ V W + G Y V + +Q + ++V A ++ ++ L
Sbjct: 419 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV-ADSQITTIGNLV 477
Query: 734 PAAHYQLRITAHNNAG 749
P Y +++ A + G
Sbjct: 478 PQKTYSVKVLAFTSIG 493
Score = 66.1 bits (154), Expect = 7e-10
Identities = 39/132 (29%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query: 66 SHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
S Q P P++++ S TI + W +P N I Y V Y P + K V
Sbjct: 407 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 466
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
S + ++ NL P +Y ++++A +G S +QV T VP G P + + E +S T
Sbjct: 467 DSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVP-GQPLNFKAEPESET 524
Query: 185 ELIVTWEPPQRD 196
++++W PP+ D
Sbjct: 525 SILLSWTPPRSD 536
Score = 46.8 bits (106), Expect = 4e-04
Identities = 81/354 (22%), Positives = 136/354 (38%), Gaps = 29/354 (8%)
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLP 406
L+ +R+ NY T A + G A + T + +P P S+ I ++W
Sbjct: 285 LNDVRQSANY--TCVAMSTLGVIEAIAQI---TVKALPKPPGTPVVTESTATSITLTW-- 337
Query: 407 PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
S N V Y Y+ + E +K + +T + + P + ++F V A +G
Sbjct: 338 -DSGNPEPVSY--YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIG 394
Query: 467 EGEATRVVTVLPSDSVP--------ARITSFSRNIVTPWKENISLSCNKVGVPAPAT--- 515
G + V S+ P AR+ S S I+ WKE + G T
Sbjct: 395 RGPPSEPVLTQTSEQAPSSAPRDVQARMLS-STTILVQWKEPEEPNGQIQGYRVYYTMDP 453
Query: 516 TWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
T +N + +++ G L T S +T S+ + ++ + VP Q
Sbjct: 454 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFT-SIGDGPLSSDIQVITQTGVPGQ 512
Query: 576 PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHVLPNL 634
P S+ L W+ I Y + YK EHG+ + + +E GTS + L L
Sbjct: 513 PLNFKAEPESETSILLSWTPPRS--DTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGL 569
Query: 635 WCGTRYQLYITAFNRIGTGLPCDIVHAYT-KGTVPVKPKHSQMITLNTTTVTVW 687
+ Y + A + G G + A T + TV K H + + + T+ + W
Sbjct: 570 KPNSLYYFRLAARSPQGLGASTAEISARTMQSTVFAKNFHVKAV-MKTSVLLSW 622
Score = 36.3 bits (80), Expect = 0.61
Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 13/121 (10%)
Query: 451 PRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNI---VTPWKENISLSCNK 507
PR + AS +GE + +TVL D +P + V ++ C
Sbjct: 90 PRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAA 149
Query: 508 VGVPAPATTW--------TMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
G P P TW T N G LR S G L I ++ +D G Y C N
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSE--SIGALQIEQSEESDQGKYECVATNSA 207
Query: 560 G 560
G
Sbjct: 208 G 208
>U42594-1|AAD00019.1| 782|Homo sapiens fibronectin protein.
Length = 782
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 127 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 181
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 182 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 236
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 237 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 277
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 278 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 332
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 333 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 388
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 389 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 440
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 441 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 500
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 501 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 554
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 555 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 610
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 611 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 653
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 582 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 633
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 634 TEATITGLEPGTEYTIYVIALKNNQKSEP 662
Score = 35.5 bits (78), Expect = 1.1
Identities = 84/409 (20%), Positives = 153/409 (37%), Gaps = 43/409 (10%)
Query: 282 VPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
+P++PP L+ + ++RV+W PPP L + V Y+PV + ED I
Sbjct: 32 IPAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKN---EEDVAELSI 84
Query: 341 SGLH--TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
S L+ L T Y V+V ++ + + P+ + + S P I + + N
Sbjct: 85 SPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITAN 140
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
V W+ +P + GY + G + P + + T + T ++
Sbjct: 141 SFTVHWI---APRATITGYRIRH---HPEHFSGRPREDRVPHSRNSITLTNLTPGT-EYV 193
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
VS G E+ ++ + S R +V ++ +S + V T
Sbjct: 194 VSIVALNGREESPLLIGQQSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRIT 249
Query: 519 MNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE---------VTYTVE 569
G S +++ T +++ +YT +V + GR + + Y E
Sbjct: 250 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 309
Query: 570 VKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAG--TS 627
+ P Q + V D +S+ ++W SP+ GY + ++G AG +
Sbjct: 310 IDKPSQ---MQVTDVQDNSISVKWL---PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 363
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E + L Y + + A N G P + A T P K +Q+
Sbjct: 364 EMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTDLKFTQV 411
>BX640638-1|CAE45786.1| 1034|Homo sapiens hypothetical protein
protein.
Length = 1034
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 128 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 182
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 183 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 237
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 238 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 278
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 279 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 333
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 334 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 389
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 390 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 441
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 442 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 501
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 502 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 555
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 556 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 611
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 612 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 654
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 583 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 634
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 635 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 674
Score = 35.5 bits (78), Expect = 1.1
Identities = 84/409 (20%), Positives = 153/409 (37%), Gaps = 43/409 (10%)
Query: 282 VPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
+P++PP L+ + ++RV+W PPP L + V Y+PV + ED I
Sbjct: 33 IPAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKN---EEDVAELSI 85
Query: 341 SGLH--TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
S L+ L T Y V+V ++ + + P+ + + S P I + + N
Sbjct: 86 SPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITAN 141
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
V W+ +P + GY + G + P + + T + T ++
Sbjct: 142 SFTVHWI---APRATITGYRIRH---HPEHFSGRPREDRVPHSRNSITLTNLTPGT-EYV 194
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
VS G E+ ++ + S R +V ++ +S + V T
Sbjct: 195 VSIVALNGREESPLLIGQQSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRIT 250
Query: 519 MNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE---------VTYTVE 569
G S +++ T +++ +YT +V + GR + + Y E
Sbjct: 251 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 310
Query: 570 VKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAG--TS 627
+ P Q + V D +S+ ++W SP+ GY + ++G AG +
Sbjct: 311 IDKPSQ---MQVTDVQDNSISVKWL---PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 364
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E + L Y + + A N G P + A T P K +Q+
Sbjct: 365 EMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTDLKFTQV 412
>BC117176-1|AAI17177.1| 2176|Homo sapiens fibronectin 1 protein.
Length = 2176
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1359 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1413
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1414 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1468
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1469 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1509
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1564
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1565 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 1620
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 1621 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 1672
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1732
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 1733 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 1786
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 1787 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 1842
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 1843 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 998 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1051
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1052 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1107
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1108 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1144
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1196
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1253
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1254 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1308
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1366
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1367 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1477
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1589
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 760
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 761 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 816
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 817 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 860
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 918
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 919 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 971
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 972 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1024
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1025 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1131
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1132 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 622 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 677
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 735
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 792
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 793 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 843
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 844 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 898
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 954
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 955 PISRNTFAEVTGLS-PGVTYYFKVFA 979
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1814 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1865
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEP 1894
>BC025843-1|AAH25843.1| 449|Homo sapiens L1CAM protein protein.
Length = 449
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/197 (30%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY------APVTDWYGNE 333
ED P P L+S +V V W P + G L+GY VTY + + ++
Sbjct: 1 EDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHK 60
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAA 393
D V + LSGLR Y++Y + V AF G G A+ T E VP P +
Sbjct: 61 DHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP-ASEFTFSTPEGVPGHPEALHLE 119
Query: 394 VSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
S +L+ W PP S NGVL GY L +++G + + P +H + P
Sbjct: 120 CQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHL 179
Query: 454 THQFWVSASTRLGEGEA 470
++F + A+T+ G GEA
Sbjct: 180 RYRFQLQATTKEGPGEA 196
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/141 (32%), Positives = 71/141 (50%), Gaps = 16/141 (11%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
V+VP + TS + L+P +SYHL + A N G S P+ +T E VP G P+ + +E
Sbjct: 63 VVVPANTTSVILSGLRPYSSYHLEVQAFNGRG-SGPASEFTFSTPEGVP-GHPEALHLEC 120
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+S+T L++ W+PP NG + GY + + L+ G G S+ +R E
Sbjct: 121 QSNTSLLLRWQPPLSH--NGVLTGYVLSYHPLDE-------GGKGQLSFNLRDPE----L 167
Query: 241 RSRTTLSGLQKHAAYAVVVQA 261
R+ L+ L H Y +QA
Sbjct: 168 RTH-NLTDLSPHLRYRFQLQA 187
Score = 57.6 bits (133), Expect = 2e-07
Identities = 61/242 (25%), Positives = 99/242 (40%), Gaps = 13/242 (5%)
Query: 166 EEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
E+ P P+ +E +S+ ++V W P G++ GY V + S
Sbjct: 1 EDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQR-----KHSK 55
Query: 226 GASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL 285
+ V A T + LSGL+ +++Y + VQA+N R E VP
Sbjct: 56 RHIHKDHVVVPANT--TSVILSGLRPYSSYHLEVQAFNGR-GSGPASEFTFSTPEGVPG- 111
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P AL S+ S+ + W+PP NG+L GY ++Y P+ + + + + L T
Sbjct: 112 HPEALHLECQSNTSLLLRWQPP--LSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRT 169
Query: 346 -TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
L+ L + Y + A T G G S +I +A + N +VSW
Sbjct: 170 HNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI-SATAGENYSVVSW 228
Query: 405 LP 406
+P
Sbjct: 229 VP 230
Score = 36.3 bits (80), Expect = 0.61
Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 6/147 (4%)
Query: 610 YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPV 669
+ + H + + V A T+ +L L + Y L + AFN G+G + + +G VP
Sbjct: 53 HSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG-VPG 111
Query: 670 KPKHSQM-ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATE-RVF 727
P+ + NT+ + W G + +V+ Y + + +S +++ E R
Sbjct: 112 HPEALHLECQSNTSLLLRWQPPLSHNGV-LTGYVLSYHPLDEGGKGQLSFNLRDPELRTH 170
Query: 728 SVSGLTPAAHY--QLRITAHNNAGHAL 752
+++ L+P Y QL+ T G A+
Sbjct: 171 NLTDLSPHLRYRFQLQATTKEGPGEAI 197
>AL832202-1|CAD91166.1| 2265|Homo sapiens hypothetical protein
protein.
Length = 2265
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1448 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1502
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1503 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1557
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1558 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1598
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1599 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1653
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1654 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 1709
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 1710 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 1761
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 1762 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1821
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 1822 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 1875
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 1876 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 1931
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 1932 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1974
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 1087 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1140
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1141 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1196
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1197 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1233
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1234 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1285
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1286 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1342
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1343 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1397
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1398 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1455
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1456 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1509
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1510 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1566
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1567 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1626
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1627 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1678
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1679 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1713
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 795 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 849
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 850 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 905
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 906 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 949
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 950 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 1007
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 1008 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 1060
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 1061 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1113
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1114 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1170
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1171 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1220
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1221 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1280
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1281 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1336
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 711 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 766
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 767 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 824
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 825 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 881
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 882 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 932
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 933 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 987
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 988 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 1043
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 1044 PISRNTFAEVTGLS-PGVTYYFKVFA 1068
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1903 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1954
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 1955 TEATITGLEPGTEYTIYVIALKNNQKSEP 1983
>AB209840-1|BAD93077.1| 2351|Homo sapiens Fibronectin 1 variant
protein.
Length = 2351
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1445 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1499
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1500 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1554
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1555 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1595
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1596 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1650
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1651 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 1706
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 1707 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 1758
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 1759 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1818
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 1819 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 1872
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 1873 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 1928
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 1929 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1971
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 1084 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1137
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1138 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1193
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1194 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1230
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1231 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1282
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1283 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1339
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1340 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1394
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1395 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1452
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1453 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1506
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1507 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1563
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1564 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1623
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1624 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1675
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1676 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1710
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 792 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 846
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 847 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 902
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 903 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 946
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 947 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 1004
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 1005 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 1057
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 1058 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1110
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1111 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1167
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1168 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1217
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1218 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1277
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1278 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1333
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 708 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 763
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 764 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 821
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 822 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 878
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 879 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 929
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 930 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 984
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 985 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 1040
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 1041 PISRNTFAEVTGLS-PGVTYYFKVFA 1065
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1900 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1951
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 1952 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 1991
>AB191261-1|BAD52437.1| 2265|Homo sapiens fibronectin 1 protein.
Length = 2265
Score = 93.9 bits (223), Expect = 3e-18
Identities = 139/583 (23%), Positives = 228/583 (39%), Gaps = 63/583 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1359 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1413
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1414 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1468
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1469 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1509
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1564
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1565 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 1620
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 1621 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 1672
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 1673 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1732
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 1733 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 1786
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 1787 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 1842
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
Y+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 1843 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1885
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 998 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1051
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1052 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1107
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1108 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1144
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1196
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1253
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1254 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1308
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1366
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1367 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1477
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1589
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 760
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 761 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 816
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 817 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 860
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 918
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 919 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 971
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 972 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1024
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1025 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1131
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1132 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 622 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 677
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 735
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 792
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 793 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 843
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 844 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 898
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 954
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 955 PISRNTFAEVTGLS-PGVTYYFKVFA 979
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1814 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1865
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 1905
>AB209287-1|BAD92524.1| 1011|Homo sapiens Fibronectin 1 variant
protein.
Length = 1011
Score = 92.7 bits (220), Expect = 7e-18
Identities = 138/581 (23%), Positives = 227/581 (39%), Gaps = 63/581 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 105 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 159
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 160 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 214
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 215 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 255
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 256 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 310
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 311 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-- 366
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
+ P+ +P AP D+K + + W P PN L GY + ++ E +
Sbjct: 367 -SQPLVQTAVTTIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTPKE---KT 418
Query: 431 GTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVLPSDSVP--ARI 486
G K + L+P + S S ++ V A L A VVT L + S P AR+
Sbjct: 419 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 478
Query: 487 TSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T + +T W+ PA T ++ T++ +V S T+T +
Sbjct: 479 TDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS-YTIT-GLQPG 532
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
D Y ++ + V + P L + + +SL + W + I G
Sbjct: 533 TDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPP---RARITG 588
Query: 606 YVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYI 644
Y+I Y++ E+ + G +E + L GT Y +Y+
Sbjct: 589 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 629
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 560 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 611
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +I +SEP + T+E+P
Sbjct: 612 TEATITGLEPGTEYTIYVITLKNNQKSEPL--IGRKKTDELP 651
Score = 35.5 bits (78), Expect = 1.1
Identities = 84/409 (20%), Positives = 153/409 (37%), Gaps = 43/409 (10%)
Query: 282 VPSLPPGA-LQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
+P++PP L+ + ++RV+W PPP L + V Y+PV + ED I
Sbjct: 10 IPAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKN---EEDVAELSI 62
Query: 341 SGLH--TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
S L+ L T Y V+V ++ + + P+ + + S P I + + N
Sbjct: 63 SPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITAN 118
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
V W+ +P + GY + G + P + + T + T ++
Sbjct: 119 SFTVHWI---APRATITGYRIRH---HPEHFSGRPREDRVPHSRNSITLTNLTPGT-EYV 171
Query: 459 VSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT 518
VS G E+ ++ + S R +V ++ +S + V T
Sbjct: 172 VSIVALNGREESPLLIGQQSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRIT 227
Query: 519 MNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDE---------VTYTVE 569
G S +++ T +++ +YT +V + GR + + Y E
Sbjct: 228 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 287
Query: 570 VKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAG--TS 627
+ P Q + V D +S+ ++W SP+ GY + ++G AG +
Sbjct: 288 IDKPSQ---MQVTDVQDNSISVKWL---PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 341
Query: 628 EHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E + L Y + + A N G P + A T P K +Q+
Sbjct: 342 EMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTDLKFTQV 389
>BC070072-1|AAH70072.1| 853|Homo sapiens FNDC3A protein protein.
Length = 853
Score = 91.1 bits (216), Expect = 2e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 26 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 82
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 83 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 141
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 142 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 185
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 186 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 245
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 246 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 302
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 303 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 360
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 361 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 416
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 417 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 468
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 469 YEIKGLSPATTYYCRVQALSVVGAGRFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 528
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 529 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 583
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 584 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 639
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 640 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 697
Score = 55.6 bits (128), Expect = 9e-07
Identities = 69/296 (23%), Positives = 117/296 (39%), Gaps = 19/296 (6%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLE 525
E E ++ P P RI + ++N +T WK + S N + W G G
Sbjct: 15 EAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNGSKIQNFVLEWD-EGKGNG 70
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DEVTYTVEVKVPPQPPILAV 581
+ + S I+ A + S N +G +EV Y P P +
Sbjct: 71 EFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVL 130
Query: 582 VDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTR 639
+ L LQWS G + Y++ + E + + + + + + NL T+
Sbjct: 131 TKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTK 190
Query: 640 YQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGC 696
Y+ + A+N G P ++V T K +PVKP I ++ +T W +GG
Sbjct: 191 YKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKIT-WDPPKDNGGA 249
Query: 697 GILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
I +V+E E S +W ++ + AT R L P Y+LR+ ++ G +
Sbjct: 250 TINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCFYRLRVYCISDGGQS 302
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 605 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 659
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 660 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 718
Query: 187 IVTWE 191
+TWE
Sbjct: 719 EITWE 723
>BC060816-1|AAH60816.1| 853|Homo sapiens FNDC3A protein protein.
Length = 853
Score = 91.1 bits (216), Expect = 2e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 26 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 82
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 83 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 141
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 142 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 185
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 186 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 245
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 246 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 302
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 303 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 360
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 361 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 416
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 417 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 468
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 469 YEIKGLSPATTYYCRVQALSVVGAGRFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 528
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 529 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 583
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 584 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 639
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 640 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 697
Score = 55.6 bits (128), Expect = 9e-07
Identities = 69/296 (23%), Positives = 117/296 (39%), Gaps = 19/296 (6%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLE 525
E E ++ P P RI + ++N +T WK + S N + W G G
Sbjct: 15 EAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNGSKIQNFVLEWD-EGKGNG 70
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DEVTYTVEVKVPPQPPILAV 581
+ + S I+ A + S N +G +EV Y P P +
Sbjct: 71 EFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVL 130
Query: 582 VDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTR 639
+ L LQWS G + Y++ + E + + + + + + NL T+
Sbjct: 131 TKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTK 190
Query: 640 YQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGC 696
Y+ + A+N G P ++V T K +PVKP I ++ +T W +GG
Sbjct: 191 YKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKIT-WDPPKDNGGA 249
Query: 697 GILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA 751
I +V+E E S +W ++ + AT R L P Y+LR+ ++ G +
Sbjct: 250 TINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCFYRLRVYCISDGGQS 302
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 605 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 659
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 660 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 718
Query: 187 IVTWE 191
+TWE
Sbjct: 719 EITWE 723
>BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein
protein.
Length = 1191
Score = 90.6 bits (215), Expect = 3e-17
Identities = 87/375 (23%), Positives = 142/375 (37%), Gaps = 30/375 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAG--NSPIINYIVQYKEAPESWPSTPQKV--IVPGSVT 128
P+ + V S + + W P + I Y V Y P + ++
Sbjct: 5 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 64
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
++ L P T+Y + + A G S+P VTTT VP P + A ++ ++
Sbjct: 65 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA--LL 122
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W PP+ G +LGY + + + I G +TV +G
Sbjct: 123 QWHPPKE--LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTV---------------TG 165
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
L K Y + A N R ED+PS P L L++ + ++W+PP
Sbjct: 166 LHKGTTYIFRLAAKN-RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPV 224
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+ RNG + Y V + + ++ T TL+GL+ T Y + V A+T+ G
Sbjct: 225 LAERNGRIISYTVVFRDINSQQELQNITTDT----RFTLTGLKPDTTYDIKVRAWTSKGS 280
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY--MSVIED 426
G + + T + + A + + +L+SW P S + LY SV D
Sbjct: 281 GPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVD 340
Query: 427 GREEGTHKRMLSPST 441
G L P+T
Sbjct: 341 GHSMRKLIADLQPNT 355
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/149 (32%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI-- 340
PS PP ++ L+S +V V W+ P ++G ++GY+VTY + + + + +
Sbjct: 1 PSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVML 60
Query: 341 -SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
TT+SGL T YSVTV A+T GDG R+ P T VP P + + ++ N
Sbjct: 61 AEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT-MMISTTAMNT 119
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
L+ W PP G L+GY L ++ R
Sbjct: 120 ALLQWHPPKELPGELLGYRLQYCRADEAR 148
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/264 (27%), Positives = 110/264 (41%), Gaps = 20/264 (7%)
Query: 169 PSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
PSGPP+ V VE +ST + V W+ P +G I GY V + L + P G
Sbjct: 1 PSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE-------PRGLP 53
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG 288
++ V A TT+SGL Y+V V AY ++ VP P
Sbjct: 54 -IIQDVMLA--EAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTM 110
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS 348
+ A++ + + W PP + G L GYR+ Y + N K H T++
Sbjct: 111 MISTTAMN--TALLQWHPP--KELPGELLGYRLQYCRADEARPNTIDFGK--DDQHFTVT 164
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP 407
GL + T Y + A AG G T ED+PS P ++ + + ++W PP
Sbjct: 165 GLHKGTTYIFRLAAKNRAGLG-EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPP 223
Query: 408 --SSPNGVLVGYTLYMSVIEDGRE 429
+ NG ++ YT+ I +E
Sbjct: 224 VLAERNGRIISYTVVFRDINSQQE 247
Score = 71.7 bits (168), Expect = 1e-11
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 23/247 (9%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQK 120
+I + + VP P + + T + W P ++ Y +QY A E+ P+T
Sbjct: 96 KIVTTTGAVPGRP-TMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNT--- 151
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
+ +V L T+Y R+ A+NR G E + ++ T E++PSG PQ++ V
Sbjct: 152 IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK-EIRTPEDLPSGFPQNLHVTG 210
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+++ + W+PP NG I+ Y V F+++NS ++ + T
Sbjct: 211 LTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQ-------------ELQNI----TT 253
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
+R TL+GL+ Y + V+A+ S+ M V + + A SV
Sbjct: 254 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTM-PVEQVFAKNFRVAAAMKTSV 312
Query: 301 RVSWEPP 307
+SWE P
Sbjct: 313 LLSWEVP 319
Score = 33.9 bits (74), Expect = 3.2
Identities = 43/186 (23%), Positives = 70/186 (37%), Gaps = 12/186 (6%)
Query: 573 PPQPPILAVVDSY-ADSLHLQWS--DQGDGGSPILGYVINYKR-EHGDWEELQVE----- 623
P PP V+ + ++H+ W I GY + Y R E+G+ L +
Sbjct: 1 PSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVML 60
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTT 683
A E + L T Y + + A+ G G T G VP +P T T
Sbjct: 61 AEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA 120
Query: 684 VTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
+ W G +L + ++Y + + + ++ F+V+GL Y R+
Sbjct: 121 LLQWHPPKELPG-ELLGYRLQYCRADEARPNTI--DFGKDDQHFTVTGLHKGTTYIFRLA 177
Query: 744 AHNNAG 749
A N AG
Sbjct: 178 AKNRAG 183
Score = 32.7 bits (71), Expect = 7.5
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 387 PADIKAAVSSRNKILVSW-LP-PSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSH 444
P ++ + + V W LP PS +G + GY + +E+G G +
Sbjct: 5 PRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ 64
Query: 445 ETSRS--PPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARIT 487
ET+ S P T+ V+A T G+G ++ V + +VP R T
Sbjct: 65 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT 109
>BC132812-1|AAI32813.1| 1198|Homo sapiens FNDC3A protein protein.
Length = 1198
Score = 90.6 bits (215), Expect = 3e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 371 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 427
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 428 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 486
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 487 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 530
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 531 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 590
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 591 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 647
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 648 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 705
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 706 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 761
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 762 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 813
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 814 YEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 873
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 874 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 928
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 929 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 984
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 985 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 1042
Score = 59.3 bits (137), Expect = 8e-08
Identities = 119/610 (19%), Positives = 218/610 (35%), Gaps = 53/610 (8%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQ----KVIVPGSVTS 129
D Q+RT+ ++W+ P S +IN PE + ST + K + G T+
Sbjct: 276 DIQARTVVLTWSPP----SSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETN 331
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ +L+PA YH ++ AE + PS+ ++ TT P R+ ++ L +
Sbjct: 332 ITLNDLKPAMDYHAKVQAEYNSIKGTPSE-AEIFTTLSCEPDIPNPPRIANRTKNSLTLQ 390
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W+ P + I + + + E N + + + A + R +
Sbjct: 391 WKAPSDN--GSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARND 448
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW-EPPP 308
+ ++ V Y S PS+P + A + + W +P
Sbjct: 449 YGTSGFSEEVLYYTSGC---------------APSMPASPVLTKA-GITWLSLQWSKPSG 492
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GI Y + T YG + + L T+ LRR T Y V A+ + G
Sbjct: 493 TPSDEGI--SYILEMEEETSGYGFKPKYDGE--DLAYTVKNLRRSTKYKFKVIAYNSEGK 548
Query: 369 GVRAAPVYCHTEEDVPSAPA--DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ V T D P P +K + S + ++W PP G + Y+ + +
Sbjct: 549 SNPSEVVEFTTCPDKPGIPVKPSVKGKIHS-HSFKITWDPPKDNGGATI--NKYVVEMAE 605
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
G + + S +T H R P ++ V + G+ + + V + +VP
Sbjct: 606 GSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLV-QTPAVPPGP 664
Query: 487 TSFSRNIVTPWKENISLSCNK--VGVPAPATTWTMNGVGLESTLRKNV--SSDGTLTISM 542
R P + I L V +P + +++ +E + V S+ T+S
Sbjct: 665 CLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSS 724
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA----VVDSYADSLHLQWSDQGD 598
+ ++ N G + ++ P PP V A + W
Sbjct: 725 LLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS 784
Query: 599 GGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
G+ + Y + + G + G S + + L T Y + A + +G G ++
Sbjct: 785 NGTDVTEYRLEWGGVEGSMQICYCGPGLS-YEIKGLSPATTYYCRVQALSVVGAGPFSEV 843
Query: 659 VHAYTKGTVP 668
V T +VP
Sbjct: 844 VACVTPPSVP 853
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/374 (23%), Positives = 147/374 (39%), Gaps = 30/374 (8%)
Query: 400 ILVSWLPPSSP-NGV--------LVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
++++W PPSS NG L GY L S +DG+ + + + TL+
Sbjct: 282 VVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAM 341
Query: 450 PPRATHQF-WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNK 507
A Q + S E E ++ P P RI + ++N +T WK + S N
Sbjct: 342 DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNG 398
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DE 563
+ W G G + + S I+ A + S N +G +E
Sbjct: 399 SKIQNFVLEWD-EGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEE 457
Query: 564 VTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQ 621
V Y P P + + L LQWS G + Y++ + E + + +
Sbjct: 458 VLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPK 517
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMIT 678
+ + + NL T+Y+ + A+N G P ++V T K +PVKP I
Sbjct: 518 YDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIH 577
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAH 737
++ +T W +GG I +V+E E S +W ++ + AT R L P
Sbjct: 578 SHSFKIT-WDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCF 633
Query: 738 YQLRITAHNNAGHA 751
Y+LR+ ++ G +
Sbjct: 634 YRLRVYCISDGGQS 647
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 950 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 1004
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 1005 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 1063
Query: 187 IVTWE 191
+TWE
Sbjct: 1064 EITWE 1068
>AL137000-1|CAI39726.2| 1142|Homo sapiens fibronectin type III
domain containing 3A protein.
Length = 1142
Score = 90.6 bits (215), Expect = 3e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 315 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 371
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 372 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 430
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 431 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 474
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 475 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 534
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 535 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 591
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 592 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 649
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 650 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 705
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 706 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 757
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 758 YEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 817
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 818 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 872
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 873 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 928
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 929 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 986
Score = 59.3 bits (137), Expect = 8e-08
Identities = 119/610 (19%), Positives = 218/610 (35%), Gaps = 53/610 (8%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQ----KVIVPGSVTS 129
D Q+RT+ ++W+ P S +IN PE + ST + K + G T+
Sbjct: 220 DIQARTVVLTWSPP----SSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETN 275
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ +L+PA YH ++ AE + PS+ ++ TT P R+ ++ L +
Sbjct: 276 ITLNDLKPAMDYHAKVQAEYNSIKGTPSE-AEIFTTLSCEPDIPNPPRIANRTKNSLTLQ 334
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W+ P + I + + + E N + + + A + R +
Sbjct: 335 WKAPSDN--GSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARND 392
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW-EPPP 308
+ ++ V Y S PS+P + A + + W +P
Sbjct: 393 YGTSGFSEEVLYYTSGC---------------APSMPASPVLTKA-GITWLSLQWSKPSG 436
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GI Y + T YG + + L T+ LRR T Y V A+ + G
Sbjct: 437 TPSDEGI--SYILEMEEETSGYGFKPKYDGE--DLAYTVKNLRRSTKYKFKVIAYNSEGK 492
Query: 369 GVRAAPVYCHTEEDVPSAPA--DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ V T D P P +K + S + ++W PP G + Y+ + +
Sbjct: 493 SNPSEVVEFTTCPDKPGIPVKPSVKGKIHS-HSFKITWDPPKDNGGATI--NKYVVEMAE 549
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
G + + S +T H R P ++ V + G+ + + V + +VP
Sbjct: 550 GSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLV-QTPAVPPGP 608
Query: 487 TSFSRNIVTPWKENISLSCNK--VGVPAPATTWTMNGVGLESTLRKNV--SSDGTLTISM 542
R P + I L V +P + +++ +E + V S+ T+S
Sbjct: 609 CLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSS 668
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA----VVDSYADSLHLQWSDQGD 598
+ ++ N G + ++ P PP V A + W
Sbjct: 669 LLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS 728
Query: 599 GGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
G+ + Y + + G + G S + + L T Y + A + +G G ++
Sbjct: 729 NGTDVTEYRLEWGGVEGSMQICYCGPGLS-YEIKGLSPATTYYCRVQALSVVGAGPFSEV 787
Query: 659 VHAYTKGTVP 668
V T +VP
Sbjct: 788 VACVTPPSVP 797
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/374 (23%), Positives = 147/374 (39%), Gaps = 30/374 (8%)
Query: 400 ILVSWLPPSSP-NGV--------LVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
++++W PPSS NG L GY L S +DG+ + + + TL+
Sbjct: 226 VVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAM 285
Query: 450 PPRATHQF-WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNK 507
A Q + S E E ++ P P RI + ++N +T WK + S N
Sbjct: 286 DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNG 342
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DE 563
+ W G G + + S I+ A + S N +G +E
Sbjct: 343 SKIQNFVLEWD-EGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEE 401
Query: 564 VTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQ 621
V Y P P + + L LQWS G + Y++ + E + + +
Sbjct: 402 VLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPK 461
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMIT 678
+ + + NL T+Y+ + A+N G P ++V T K +PVKP I
Sbjct: 462 YDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIH 521
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAH 737
++ +T W +GG I +V+E E S +W ++ + AT R L P
Sbjct: 522 SHSFKIT-WDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCF 577
Query: 738 YQLRITAHNNAGHA 751
Y+LR+ ++ G +
Sbjct: 578 YRLRVYCISDGGQS 591
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 894 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 948
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 949 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 1007
Query: 187 IVTWE 191
+TWE
Sbjct: 1008 EITWE 1012
>AJ749707-1|CAG44603.1| 1134|Homo sapiens human gene expressed in
odontoblast protein protein.
Length = 1134
Score = 90.6 bits (215), Expect = 3e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 307 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 363
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 364 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 422
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 423 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 466
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 467 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 526
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 527 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 583
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 584 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 641
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 642 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 697
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 698 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 749
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 750 YEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 809
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 810 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 864
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 865 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 920
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 921 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 978
Score = 59.3 bits (137), Expect = 8e-08
Identities = 119/610 (19%), Positives = 218/610 (35%), Gaps = 53/610 (8%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQ----KVIVPGSVTS 129
D Q+RT+ ++W+ P S +IN PE + ST + K + G T+
Sbjct: 212 DIQARTVVLTWSPP----SSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETN 267
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ +L+PA YH ++ AE + PS+ ++ TT P R+ ++ L +
Sbjct: 268 ITLNDLKPAMDYHAKVQAEYNSIKGTPSE-AEIFTTLSCEPDIPNPPRIANRTKNSLTLQ 326
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W+ P + I + + + E N + + + A + R +
Sbjct: 327 WKAPSDN--GSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARND 384
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW-EPPP 308
+ ++ V Y S PS+P + A + + W +P
Sbjct: 385 YGTSGFSEEVLYYTSGC---------------APSMPASPVLTKA-GITWLSLQWSKPSG 428
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GI Y + T YG + + L T+ LRR T Y V A+ + G
Sbjct: 429 TPSDEGI--SYILEMEEETSGYGFKPKYDGE--DLAYTVKNLRRSTKYKFKVIAYNSEGK 484
Query: 369 GVRAAPVYCHTEEDVPSAPA--DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ V T D P P +K + S + ++W PP G + Y+ + +
Sbjct: 485 SNPSEVVEFTTCPDKPGIPVKPSVKGKIHS-HSFKITWDPPKDNGGATI--NKYVVEMAE 541
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
G + + S +T H R P ++ V + G+ + + V + +VP
Sbjct: 542 GSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLV-QTPAVPPGP 600
Query: 487 TSFSRNIVTPWKENISLSCNK--VGVPAPATTWTMNGVGLESTLRKNV--SSDGTLTISM 542
R P + I L V +P + +++ +E + V S+ T+S
Sbjct: 601 CLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSS 660
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA----VVDSYADSLHLQWSDQGD 598
+ ++ N G + ++ P PP V A + W
Sbjct: 661 LLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS 720
Query: 599 GGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
G+ + Y + + G + G S + + L T Y + A + +G G ++
Sbjct: 721 NGTDVTEYRLEWGGVEGSMQICYCGPGLS-YEIKGLSPATTYYCRVQALSVVGAGPFSEV 779
Query: 659 VHAYTKGTVP 668
V T +VP
Sbjct: 780 VACVTPPSVP 789
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/374 (23%), Positives = 147/374 (39%), Gaps = 30/374 (8%)
Query: 400 ILVSWLPPSSP-NGV--------LVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
++++W PPSS NG L GY L S +DG+ + + + TL+
Sbjct: 218 VVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAM 277
Query: 450 PPRATHQF-WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNK 507
A Q + S E E ++ P P RI + ++N +T WK + S N
Sbjct: 278 DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNG 334
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DE 563
+ W G G + + S I+ A + S N +G +E
Sbjct: 335 SKIQNFVLEWD-EGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEE 393
Query: 564 VTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQ 621
V Y P P + + L LQWS G + Y++ + E + + +
Sbjct: 394 VLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPK 453
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMIT 678
+ + + NL T+Y+ + A+N G P ++V T K +PVKP I
Sbjct: 454 YDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIH 513
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAH 737
++ +T W +GG I +V+E E S +W ++ + AT R L P
Sbjct: 514 SHSFKIT-WDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCF 569
Query: 738 YQLRITAHNNAGHA 751
Y+LR+ ++ G +
Sbjct: 570 YRLRVYCISDGGQS 583
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 886 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 940
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 941 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 999
Query: 187 IVTWE 191
+TWE
Sbjct: 1000 EITWE 1004
>AJ749706-1|CAG44602.1| 1198|Homo sapiens human gene expressed in
odontoblast protein protein.
Length = 1198
Score = 90.6 bits (215), Expect = 3e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 371 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 427
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 428 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 486
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 487 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 530
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 531 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 590
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 591 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 647
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 648 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 705
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 706 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 761
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 762 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 813
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 814 YEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 873
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 874 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 928
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 929 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 984
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 985 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 1042
Score = 59.3 bits (137), Expect = 8e-08
Identities = 119/610 (19%), Positives = 218/610 (35%), Gaps = 53/610 (8%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQ----KVIVPGSVTS 129
D Q+RT+ ++W+ P S +IN PE + ST + K + G T+
Sbjct: 276 DIQARTVVLTWSPP----SSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETN 331
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ +L+PA YH ++ AE + PS+ ++ TT P R+ ++ L +
Sbjct: 332 ITLNDLKPAMDYHAKVQAEYNSIKGTPSE-AEIFTTLSCEPDIPNPPRIANRTKNSLTLQ 390
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W+ P + I + + + E N + + + A + R +
Sbjct: 391 WKAPSDN--GSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARND 448
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW-EPPP 308
+ ++ V Y S PS+P + A + + W +P
Sbjct: 449 YGTSGFSEEVLYYTSGC---------------APSMPASPVLTKA-GITWLSLQWSKPSG 492
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GI Y + T YG + + L T+ LRR T Y V A+ + G
Sbjct: 493 TPSDEGI--SYILEMEEETSGYGFKPKYDGE--DLAYTVKNLRRSTKYKFKVIAYNSEGK 548
Query: 369 GVRAAPVYCHTEEDVPSAPA--DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ V T D P P +K + S + ++W PP G + Y+ + +
Sbjct: 549 SNPSEVVEFTTCPDKPGIPVKPSVKGKIHS-HSFKITWDPPKDNGGATI--NKYVVEMAE 605
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
G + + S +T H R P ++ V + G+ + + V + +VP
Sbjct: 606 GSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLV-QTPAVPPGP 664
Query: 487 TSFSRNIVTPWKENISLSCNK--VGVPAPATTWTMNGVGLESTLRKNV--SSDGTLTISM 542
R P + I L V +P + +++ +E + V S+ T+S
Sbjct: 665 CLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSS 724
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA----VVDSYADSLHLQWSDQGD 598
+ ++ N G + ++ P PP V A + W
Sbjct: 725 LLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS 784
Query: 599 GGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
G+ + Y + + G + G S + + L T Y + A + +G G ++
Sbjct: 785 NGTDVTEYRLEWGGVEGSMQICYCGPGLS-YEIKGLSPATTYYCRVQALSVVGAGPFSEV 843
Query: 659 VHAYTKGTVP 668
V T +VP
Sbjct: 844 VACVTPPSVP 853
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/374 (23%), Positives = 147/374 (39%), Gaps = 30/374 (8%)
Query: 400 ILVSWLPPSSP-NGV--------LVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
++++W PPSS NG L GY L S +DG+ + + + TL+
Sbjct: 282 VVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAM 341
Query: 450 PPRATHQF-WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNK 507
A Q + S E E ++ P P RI + ++N +T WK + S N
Sbjct: 342 DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNG 398
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DE 563
+ W G G + + S I+ A + S N +G +E
Sbjct: 399 SKIQNFVLEWD-EGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEE 457
Query: 564 VTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQ 621
V Y P P + + L LQWS G + Y++ + E + + +
Sbjct: 458 VLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPK 517
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMIT 678
+ + + NL T+Y+ + A+N G P ++V T K +PVKP I
Sbjct: 518 YDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIH 577
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAH 737
++ +T W +GG I +V+E E S +W ++ + AT R L P
Sbjct: 578 SHSFKIT-WDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCF 633
Query: 738 YQLRITAHNNAGHA 751
Y+LR+ ++ G +
Sbjct: 634 YRLRVYCISDGGQS 647
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 950 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 1004
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 1005 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 1063
Query: 187 IVTWE 191
+TWE
Sbjct: 1064 EITWE 1068
>AB023187-1|BAA76814.2| 1151|Homo sapiens KIAA0970 protein protein.
Length = 1151
Score = 90.6 bits (215), Expect = 3e-17
Identities = 164/719 (22%), Positives = 273/719 (37%), Gaps = 76/719 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P++P R+ ++ ++ + W P S I N+++++ E + + GS
Sbjct: 324 PDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYM---GSQKQ 380
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA R+ A N G S S+ V T+ PS P V +A T L +
Sbjct: 381 FKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQ 439
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + I Y + +E S G + + +G A T+ L
Sbjct: 440 WSKPSGTPSDEGI-SYILEMEEETS-----------GYGFKPK-YDGEDLAY---TVKNL 483
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y V AYNS D P +P + S S +++W+PP
Sbjct: 484 RRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKD 543
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
G + Y V A ++ GN+ + + L Y + V + G
Sbjct: 544 NG-GATINKYVVEMAEGSN--GNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS 600
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNK---ILVSWLPPSSPNGVLVG-YTLYMSVIE 425
+ + T VP P + + R K I + W PP G + Y++ MS IE
Sbjct: 601 AVSESLLVQTPA-VPPGPC-LPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE 658
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--LPSD 480
++E + + S + S P T+ F + A+ ++G G E + T P
Sbjct: 659 --KDE--PREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQ 714
Query: 481 SVPARITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT 539
P ++T S W+ +S N V T + + G+E +++ G L+
Sbjct: 715 CKPPQVTCRSATCAQVNWEVPLS---NGTDV----TEYRLEWGGVEGSMQICYCGPG-LS 766
Query: 540 ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQ-PPILAVVDSYADS-------- 588
+ + + Y C V+ ++ G + V PP P I+ + +D
Sbjct: 767 YEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 826
Query: 589 ----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
L + W D GS IL Y I++ GD + L V TS +++ NL T Y++ I
Sbjct: 827 PSTCLAISWEKPCDHGSEILAYSIDF----GDKQSLTVGKVTS-YIINNLQPDTTYRIRI 881
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYF-VI 703
A N +G G ++ TK +P P + + + + + WG+G L I
Sbjct: 882 QALNSLGAGPFSHMIKLKTK-PLPPDPPRLECVAFSHQNLKL---KWGEGTPKTLSTDSI 937
Query: 704 EYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+Y +M R VS + + V L + Y+ I A N AG Y FTT
Sbjct: 938 QYHLQMEDKNGRFVS-LYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTT 995
Score = 59.3 bits (137), Expect = 8e-08
Identities = 119/610 (19%), Positives = 218/610 (35%), Gaps = 53/610 (8%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQ----KVIVPGSVTS 129
D Q+RT+ ++W+ P S +IN PE + ST + K + G T+
Sbjct: 229 DIQARTVVLTWSPP----SSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETN 284
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ +L+PA YH ++ AE + PS+ ++ TT P R+ ++ L +
Sbjct: 285 ITLNDLKPAMDYHAKVQAEYNSIKGTPSE-AEIFTTLSCEPDIPNPPRIANRTKNSLTLQ 343
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W+ P + I + + + E N + + + A + R +
Sbjct: 344 WKAPSDN--GSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARND 401
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW-EPPP 308
+ ++ V Y S PS+P + A + + W +P
Sbjct: 402 YGTSGFSEEVLYYTSGC---------------APSMPASPVLTKA-GITWLSLQWSKPSG 445
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
GI Y + T YG + + L T+ LRR T Y V A+ + G
Sbjct: 446 TPSDEGI--SYILEMEEETSGYGFKPKYDGE--DLAYTVKNLRRSTKYKFKVIAYNSEGK 501
Query: 369 GVRAAPVYCHTEEDVPSAPA--DIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ V T D P P +K + S + ++W PP G + Y+ + +
Sbjct: 502 SNPSEVVEFTTCPDKPGIPVKPSVKGKIHS-HSFKITWDPPKDNGGATI--NKYVVEMAE 558
Query: 427 GREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
G + + S +T H R P ++ V + G+ + + V + +VP
Sbjct: 559 GSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLV-QTPAVPPGP 617
Query: 487 TSFSRNIVTPWKENISLSCNK--VGVPAPATTWTMNGVGLESTLRKNV--SSDGTLTISM 542
R P + I L V +P + +++ +E + V S+ T+S
Sbjct: 618 CLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSS 677
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA----VVDSYADSLHLQWSDQGD 598
+ ++ N G + ++ P PP V A + W
Sbjct: 678 LLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLS 737
Query: 599 GGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
G+ + Y + + G + G S + + L T Y + A + +G G ++
Sbjct: 738 NGTDVTEYRLEWGGVEGSMQICYCGPGLS-YEIKGLSPATTYYCRVQALSVVGAGPFSEV 796
Query: 659 VHAYTKGTVP 668
V T +VP
Sbjct: 797 VACVTPPSVP 806
Score = 57.6 bits (133), Expect = 2e-07
Identities = 88/374 (23%), Positives = 147/374 (39%), Gaps = 30/374 (8%)
Query: 400 ILVSWLPPSSP-NGV--------LVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETSRS 449
++++W PPSS NG L GY L S +DG+ + + + TL+
Sbjct: 235 VVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAM 294
Query: 450 PPRATHQF-WVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT-PWKENISLSCNK 507
A Q + S E E ++ P P RI + ++N +T WK + S N
Sbjct: 295 DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWK---APSDNG 351
Query: 508 VGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR----DE 563
+ W G G + + S I+ A + S N +G +E
Sbjct: 352 SKIQNFVLEWD-EGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEE 410
Query: 564 VTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGYVINYKREHGDWE-ELQ 621
V Y P P + + L LQWS G + Y++ + E + + +
Sbjct: 411 VLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPK 470
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVKPKHSQMIT 678
+ + + NL T+Y+ + A+N G P ++V T K +PVKP I
Sbjct: 471 YDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIH 530
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQ-PQWRLVSNSVQATERVFSVSGLTPAAH 737
++ +T W +GG I +V+E E S +W ++ + AT R L P
Sbjct: 531 SHSFKIT-WDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSG--AT-REHLCDRLNPGCF 586
Query: 738 YQLRITAHNNAGHA 751
Y+LR+ ++ G +
Sbjct: 587 YRLRVYCISDGGQS 600
Score = 33.1 bits (72), Expect = 5.6
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 8/125 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+P P + + + +++ W + P ++ I Y +Q ++ + S + G
Sbjct: 903 LPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVS-----LYRGP 957
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ VQ L +TSY I A N G+ SQ TT + VP+ + ++E +
Sbjct: 958 CHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAA-LKAPKIEKVNDHIC 1016
Query: 187 IVTWE 191
+TWE
Sbjct: 1017 EITWE 1021
>BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa protein.
Length = 1589
Score = 90.2 bits (214), Expect = 4e-17
Identities = 110/510 (21%), Positives = 201/510 (39%), Gaps = 43/510 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP P ++ V + + +SW P G+ I+ ++ + + E+W ++ P
Sbjct: 637 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTEL--PVKS 694
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSGPPQDVRVEAKSST 184
++ +L SY R+ N G EPS+ +VT ++P P + + + T
Sbjct: 695 PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK-IIPSRNTDT 753
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++V+WE +D ++GYY+ S + P V+G SR
Sbjct: 754 SVVVSWE-ESKDA--KELVGYYIEASVAGSGKWEPCNNNP---------VKG-----SRF 796
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRV 302
T GL +Y V+A N+ ++ P PP + C S+ +
Sbjct: 797 TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVL 856
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYSVTV 360
W+ P G + GY V Y V D + +A K +S +S L+ Y V
Sbjct: 857 GWKQPDKIG-GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQV 915
Query: 361 CAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
A AG G +A C E+ VP P +K + ++ +++ W PP V
Sbjct: 916 AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPV- 974
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSH---ETSRSPPRATHQFWVSASTRLGEGEATRV 473
T Y +++ + + R L+ + + + + ++ F V A + G G+ + +
Sbjct: 975 -TGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDL 1033
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
+ +++ P N+ +++ C+K+ P +W+ + V E + R V
Sbjct: 1034 AGPVVAETRPG-TKEVVVNVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEVE 1091
Query: 534 SDGT---LTISMTQSADSGNYTCSVENIHG 560
S G +T D G Y+C V + G
Sbjct: 1092 SKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1121
Score = 81.4 bits (192), Expect = 2e-14
Identities = 101/405 (24%), Positives = 161/405 (39%), Gaps = 45/405 (11%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPS--SPNGVLVGYTLYMSVIEDGREEGTHKRM 436
+E VP P D+ ++R+ +++SW PP G++ + E+ + T +
Sbjct: 633 SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPV 692
Query: 437 LSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--------LPSDSVPAR 485
SP + + ++ F V S G G EAT V V P +P+R
Sbjct: 693 KSPRFALFDLAEG---KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSR 749
Query: 486 ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T S +V W+E+ VG A ++ G G N T +
Sbjct: 750 NTDTS--VVVSWEESKDAK-ELVGYYIEA---SVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
Query: 546 ADSGNYTCSVENIHGRDEVTY---TVEVK---VPPQPPI-LAVVDSYADSLHLQWSDQGD 598
S + N G E + +EVK PP PP + ++S+ DS+ L W
Sbjct: 804 GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDK 863
Query: 599 -GGSPILGYVINYKR----EHGDWEELQVEAGTSE-HVLPNLWCGTRYQLYITAFNRIGT 652
GG+ I GY +NY+ G W E V+A + E + + NL YQ + A N G
Sbjct: 864 IGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGL 923
Query: 653 GLPCDIVHAY--TKGTVPVK-PKHSQMIT--LNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
G P + + + T+ V P HS + + V W G + + ++ +E
Sbjct: 924 GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 983
Query: 708 --MSQPQWRLVSNSVQATERVF-SVSGLTPAAHYQLRITAHNNAG 749
+ QWR ++ + A + V+ V GL Y R+ A N AG
Sbjct: 984 AKAKEDQWRGLNEA--AIKNVYLKVRGLKEGVSYVFRVRAINQAG 1026
Score = 66.1 bits (154), Expect = 7e-10
Identities = 105/430 (24%), Positives = 153/430 (35%), Gaps = 36/430 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P P +++ ++ I ISW QP G SPI+ Y + E +SW P
Sbjct: 510 PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCND---TPVKF 566
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
V L SY R+ A N++G PS+ + + R A + ++I
Sbjct: 567 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVFEPVAALDPAEKARLKGRPSAPWTGQII 626
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG-----GASYTVRTVEGAGTAR- 241
VT E P + G V E + VL PG G Y V E AGT
Sbjct: 627 VTEEEPSEGIVPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCE-AGTENW 683
Query: 242 -----------SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PG 288
R L L + +Y V+ NS + D +P PG
Sbjct: 684 QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPG 743
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS 348
+ + + SV VSWE L GY + A V E + G T
Sbjct: 744 KIIPSRNTDTSVVVSWEESKDAKE---LVGYYIE-ASVAGSGKWEPCNNNPVKGSRFTCH 799
Query: 349 GLRRYTNYSVTVCAFTAAG---DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
GL +Y V A AAG + + PS P DI S R+ +++ W
Sbjct: 800 GLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWK 859
Query: 406 PPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
P G + GY + Y VI+ + + + S +++ S +QF V+A
Sbjct: 860 QPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMN 919
Query: 464 RLGEGEATRV 473
G G + V
Sbjct: 920 MAGLGAPSAV 929
Score = 64.1 bits (149), Expect = 3e-09
Identities = 128/549 (23%), Positives = 202/549 (36%), Gaps = 57/549 (10%)
Query: 167 EVPSGP--PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS-------T 217
E+ P P DV+ + +I++W+ P D ILGY++ E+ ++S
Sbjct: 505 EIEGAPAAPLDVKCLEANKDYIIISWKQPAVD-GGSPILGYFIDKCEVGTDSWSQCNDTP 563
Query: 218 VLIASGP-----GGASYT--VRTVEGAGTA-RSRTTLSGLQKHAAYAVVVQAYNSRXXXX 269
V A P G SY VR V G SR A ++ S
Sbjct: 564 VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVFEPVAALDPAEKARLKGRPSAPWTG 623
Query: 270 XXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW 329
E + PP L + V +SW+PP RG GI+ A +W
Sbjct: 624 QIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENW 683
Query: 330 YGNEDAVTKQISGLHTTLSGLRRYTNYSVTV-CAFTA-AGDGVRAAPVYCHTEE-DVPSA 386
+ + L L +Y V C+ +A G+ A V ++ D+P A
Sbjct: 684 QRVNTEL--PVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKA 741
Query: 387 PADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS-H- 444
P I + ++ ++VSW S LVGY + SV G+ E + + S + H
Sbjct: 742 PGKIIPSRNTDTSVVVSW-EESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHG 800
Query: 445 -ETSRS---PPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARIT---SFSRNIVTPW 497
T +S RA + +S ++ + EA V + S P IT SF ++V W
Sbjct: 801 LVTGQSYIFRVRAVNAAGLSEYSQ--DSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGW 858
Query: 498 KENISLSCNKV------------GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
K+ + ++ GVP + V E+ N+ + +
Sbjct: 859 KQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAM 918
Query: 546 ADSG-NYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPI 603
+G +V +E T + VP P L + DSL LQW G +P+
Sbjct: 919 NMAGLGAPSAVSECFKCEEWT----IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPV 974
Query: 604 LGYVINYKR---EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
GY ++ K + W L A + ++ + L G Y + A N+ G G P D+
Sbjct: 975 TGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLA 1034
Query: 660 HAYTKGTVP 668
T P
Sbjct: 1035 GPVVAETRP 1043
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 484 ARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLES----TLRKNVSSDGTL 538
AR+ ++VT + + ++L+CN G P P +W N L S L+
Sbjct: 1476 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1535
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
TI+ +ADSG Y V+N +G + +TV V +P + +A ++S
Sbjct: 1536 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1581
Score = 46.4 bits (105), Expect = 6e-04
Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 499 ENISLSCNKVGVPA-----PATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGN 550
E +SL C V P P W NGV L + G TLT S D G
Sbjct: 420 ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
Query: 551 YTCSVENIHGRDEVTYTV-------EVKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGS 601
YT V ++ + V E++ P P+ + +++ D + + W DGGS
Sbjct: 480 YTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGS 539
Query: 602 PILGYVINYKREHG--DWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
PILGY I+ K E G W + + + L G Y + A N++G G P
Sbjct: 540 PILGYFID-KCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
Score = 35.9 bits (79), Expect = 0.80
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 495 TPW-KENISLSCNKVGVPAPATTWTMNGV--GLESTLRKNV--SSDG--TLTISMTQSAD 547
T W KEN+ L C+ G P P TW N V + + K + S G TL I+ D
Sbjct: 287 TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINACDFED 346
Query: 548 SGNYTCSVENIHGRDEVTYTVEVK 571
+ Y S N+ G +V VK
Sbjct: 347 TAQYRASAMNVKGELSAYASVVVK 370
>X02761-1|CAA26536.1| 2328|Homo sapiens fibronectin precursor protein.
Length = 2328
Score = 89.8 bits (213), Expect = 5e-17
Identities = 155/685 (22%), Positives = 255/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1332 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1386
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1387 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1441
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1442 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1482
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1483 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1537
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1538 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1595
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1596 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1644
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1645 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1702
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1703 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1762
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1763 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 1814
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1815 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1873
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1874 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1927
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 1928 VTEA-TITGLEPGTEYTIYVIALKN 1951
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 971 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1024
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1025 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1080
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1081 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1117
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1118 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1169
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1170 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1226
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1227 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1281
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1282 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1339
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1340 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1393
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1394 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1450
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1451 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1510
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1511 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1562
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1563 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1597
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 679 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 733
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 734 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 789
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 790 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 833
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 834 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 891
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 892 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 944
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 945 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 997
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 998 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1054
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1055 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1104
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1105 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1164
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1165 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1220
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 595 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 650
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 651 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 708
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 709 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 765
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 766 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 816
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 817 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 871
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 872 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 927
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 928 PISRNTFAEVTGLS-PGVTYYFKVFA 952
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1877 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1928
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 1929 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 1968
>BX640999-1|CAE46002.1| 2193|Homo sapiens hypothetical protein
protein.
Length = 2193
Score = 89.8 bits (213), Expect = 5e-17
Identities = 155/685 (22%), Positives = 255/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1197 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1251
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1252 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1306
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1307 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1347
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1348 PGVDYTITVHAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1402
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1403 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1460
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1461 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1509
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1510 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1567
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1568 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1627
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1628 VSVYALKDTLTSRPAQG---VVTTLENVGPPRR--ARVTDATETTITISWRTKTE---TI 1679
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1680 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1738
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1739 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1792
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 1793 VTEA-TITGLEPGTEYTIYVIALKN 1816
Score = 66.9 bits (156), Expect = 4e-10
Identities = 148/691 (21%), Positives = 248/691 (35%), Gaps = 76/691 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 745 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 798
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 799 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 854
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 855 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 891
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 892 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 943
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 944 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1000
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ +VP D+ + + I + W P +S ++GY + +V+ G
Sbjct: 1001 KESVPISDTIIPEVPQL-TDLSFVDITDSSIGLRWTPLNS--STIIGYRI--TVVAAGEG 1055
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV--TVLPSDSVPARIT 487
+ + S + + P + V GE T + T +P + R T
Sbjct: 1056 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT-DLRFT 1114
Query: 488 SFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
+ + + W S+ V + V E + + S + +T
Sbjct: 1115 NIGPDTMRVTWAPPPSIDLTNFLV-------RYSPVKNEEDVAELSISPSDNAVVLTNLL 1167
Query: 547 DSGNYTCSVENIHGRDEVT-YTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPIL 604
Y SV +++ + E T K P + D A+S + W + I
Sbjct: 1168 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP---RATIT 1224
Query: 605 GYVINYKREH--GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
GY I + EH G E +V + L NL GT Y + I A N G +
Sbjct: 1225 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIG 1280
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
+ TV P+ +++ T++ + SW + Y+ I Y E + +V
Sbjct: 1281 QQSTVSDVPRDLEVVAATPTSLLI---SWDAPAVTVRYYRITYGETGGNS-PVQEFTVPG 1336
Query: 723 TERVFSVSGLTPAAHYQLRITAHNNAGHALA 753
++ ++SGL P Y + + A G + A
Sbjct: 1337 SKSTATISGLKPGVDYTITVHAVTGRGDSPA 1367
Score = 64.9 bits (151), Expect = 2e-09
Identities = 134/593 (22%), Positives = 219/593 (36%), Gaps = 72/593 (12%)
Query: 69 VPEMPK--NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+PE+P+ ++ +D +I + WT +S II Y + A E P V S
Sbjct: 1011 IPEVPQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYRITVVAAGEGIPIFED--FVDSS 1066
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
V +V L+P Y + +I G+S P+ T T++ PP D+R +
Sbjct: 1067 VGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTM 1121
Query: 187 IVTWEPPQR-DLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
VTW PP DL N + V + + + V A ++ + A
Sbjct: 1122 RVTWAPPPSIDLTN-----FLVRYSPVKNEEDV--------AELSISPSDNA------VV 1162
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L Y V V + + ++ P + + +++ S V W
Sbjct: 1163 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-----PTGIDFSDITANSFTVHWI 1217
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
P + GYR+ + P ED V + + TL+ L T Y V++ A
Sbjct: 1218 AP-----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLTPGTEYVVSIVAL- 1269
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
+G +P+ + V P D++ ++ +L+SW P+ V V Y ++
Sbjct: 1270 ---NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRY-YRITYG 1321
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
E G + + S + S P + V A T G+ A+ S +
Sbjct: 1322 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVHAVTGRGDSPASSKPI---SINYRT 1378
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPAP-----ATTWTMNGVGLESTLRKNVSSDGT-L 538
I S+ VT ++N S+S + +P TT NG G T K D T +
Sbjct: 1379 EIDKPSQMQVTDVQDN-SISVKWLPSSSPVTGYRVTTTPKNGPG--PTKTKTAGPDQTEM 1435
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW-SDQG 597
TI Q + +N G + V +P LA D DS+ + W S QG
Sbjct: 1436 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1495
Query: 598 DGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
+ Y + Y E G E G + L L G+ Y + + A +
Sbjct: 1496 Q----VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1544
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 453 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 507
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 508 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 563
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 564 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 607
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 608 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 665
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 666 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 718
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 719 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 771
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 772 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 828
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 829 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 878
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 879 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 938
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 939 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 994
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 369 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 424
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 425 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 482
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 483 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 539
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 540 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 590
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 591 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 645
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 646 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 701
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 702 PISRNTFAEVTGLS-PGVTYYFKVFA 726
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1742 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1793
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 1794 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 1833
>BX640920-1|CAE45958.1| 1255|Homo sapiens hypothetical protein
protein.
Length = 1255
Score = 89.8 bits (213), Expect = 5e-17
Identities = 155/685 (22%), Positives = 255/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 259 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 313
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 314 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 368
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 369 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 409
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 410 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 464
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 465 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 522
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 523 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 571
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 572 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 629
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 630 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 689
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 690 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 741
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 742 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 800
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 801 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 854
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 855 VTEA-TITGLEPGTEYTIYVIALKN 878
Score = 50.4 bits (115), Expect = 3e-05
Identities = 118/538 (21%), Positives = 194/538 (36%), Gaps = 66/538 (12%)
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
+V +S + NL P Y++ + + + S P+ T VP PP D+R
Sbjct: 124 VVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVP--PPTDLRFTNI 178
Query: 182 SSTELIVTWEPPQR-DLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ VTW PP DL N + V + + + V A ++ + A
Sbjct: 179 GPDTMRVTWAPPPSIDLTN-----FLVRYSPVKNEEDV--------AELSISPSDNA--- 222
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
L+ L Y V V + + ++ P + + +++ S
Sbjct: 223 ---VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-----PTGIDFSDITANSF 274
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVT 359
V W P + GYR+ + P ED V + + TL+ L T Y V+
Sbjct: 275 TVHWIAP-----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLTPGTEYVVS 327
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ A +G +P+ + V P D++ ++ +L+SW P+ V V Y
Sbjct: 328 IVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRY-Y 378
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
++ E G + + S + S P + V A T G+ A+ S
Sbjct: 379 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI---S 435
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAP-----ATTWTMNGVGLESTLRKNVSS 534
+ I S+ VT ++N S+S + +P TT NG G T K
Sbjct: 436 INYRTEIDKPSQMQVTDVQDN-SISVKWLPSSSPVTGYRVTTTPKNGPG--PTKTKTAGP 492
Query: 535 DGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
D T +TI Q + +N G + V +P LA D DS+ + W
Sbjct: 493 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 552
Query: 594 -SDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
S QG + Y + Y E G E G + L L G+ Y + + A +
Sbjct: 553 ESPQGQ----VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 606
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 804 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 855
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 856 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 895
>BX537590-1|CAD97791.1| 2446|Homo sapiens hypothetical protein
protein.
Length = 2446
Score = 89.8 bits (213), Expect = 5e-17
Identities = 155/685 (22%), Positives = 255/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1450 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1504
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1505 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1559
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1560 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1600
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1601 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1655
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1656 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1714 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1762
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1763 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1820
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1821 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1881 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 1932
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1991
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1992 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 2046 VTEA-TITGLEPGTEYTIYVIALKN 2069
Score = 67.3 bits (157), Expect = 3e-10
Identities = 148/691 (21%), Positives = 248/691 (35%), Gaps = 76/691 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 998 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1051
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1052 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1107
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1108 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1144
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1196
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNSLGEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1253
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ +VP D+ + + I + W P +S ++GY + +V+ G
Sbjct: 1254 KESVPISDTIIPEVPQL-TDLSFVDITDSSIGLRWTPLNS--STIIGYRI--TVVAAGEG 1308
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV--TVLPSDSVPARIT 487
+ + S + + P + V GE T + T +P + R T
Sbjct: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT-DLRFT 1367
Query: 488 SFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA 546
+ + + W S+ V + V E + + S + +T
Sbjct: 1368 NIGPDTMRVTWAPPPSIDLTNFLV-------RYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
Query: 547 DSGNYTCSVENIHGRDEVT-YTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGDGGSPIL 604
Y SV +++ + E T K P + D A+S + W + I
Sbjct: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP---RATIT 1477
Query: 605 GYVINYKREH--GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
GY I + EH G E +V + L NL GT Y + I A N G +
Sbjct: 1478 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIG 1533
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
+ TV P+ +++ T++ + SW + Y+ I Y E + +V
Sbjct: 1534 QQSTVSDVPRDLEVVAATPTSLLI---SWDAPAVTVRYYRITYGETGGNS-PVQEFTVPG 1589
Query: 723 TERVFSVSGLTPAAHYQLRITAHNNAGHALA 753
++ ++SGL P Y + + A G + A
Sbjct: 1590 SKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
Score = 64.5 bits (150), Expect = 2e-09
Identities = 134/593 (22%), Positives = 219/593 (36%), Gaps = 72/593 (12%)
Query: 69 VPEMPK--NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
+PE+P+ ++ +D +I + WT +S II Y + A E P V S
Sbjct: 1264 IPEVPQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYRITVVAAGEGIPIFED--FVDSS 1319
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
V +V L+P Y + +I G+S P+ T T++ PP D+R +
Sbjct: 1320 VGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTM 1374
Query: 187 IVTWEPPQR-DLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
VTW PP DL N + V + + + V A ++ + A
Sbjct: 1375 RVTWAPPPSIDLTN-----FLVRYSPVKNEEDV--------AELSISPSDNA------VV 1415
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L Y V V + + ++ P + + +++ S V W
Sbjct: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-----PTGIDFSDITANSFTVHWI 1470
Query: 306 PPPMRGRNGILQGYRVTYAPV-TDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
P + GYR+ + P ED V + + TL+ L T Y V++ A
Sbjct: 1471 AP-----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLTPGTEYVVSIVAL- 1522
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
+G +P+ + V P D++ ++ +L+SW P+ V V Y ++
Sbjct: 1523 ---NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA----VTVRY-YRITYG 1574
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
E G + + S + S P + V A T G+ A+ S +
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI---SINYRT 1631
Query: 485 RITSFSRNIVTPWKENISLSCNKVGVPAP-----ATTWTMNGVGLESTLRKNVSSDGT-L 538
I S+ VT ++N S+S + +P TT NG G T K D T +
Sbjct: 1632 EIDKPSQMQVTDVQDN-SISVKWLPSSSPVTGYRVTTTPKNGPG--PTKTKTAGPDQTEM 1688
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW-SDQG 597
TI Q + +N G + V +P LA D DS+ + W S QG
Sbjct: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
Query: 598 DGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFN 648
+ Y + Y E G E G + L L G+ Y + + A +
Sbjct: 1749 Q----VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1797
Score = 58.8 bits (136), Expect = 1e-07
Identities = 94/446 (21%), Positives = 167/446 (37%), Gaps = 48/446 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 760
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 761 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 816
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 817 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 860
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 918
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 919 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 971
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A + G + P+ + AP +++ + + +LV W PP + +
Sbjct: 972 TYYFKVFALS---HGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1024
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1025 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPW 497
T L P S+P T + IV W
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITW 1107
Score = 52.4 bits (120), Expect = 9e-06
Identities = 83/409 (20%), Positives = 153/409 (37%), Gaps = 37/409 (9%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 622 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 677
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 735
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 792
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 793 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 843
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 844 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 898
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 954
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
+S +T + T S P T+ F V A L G ++ +T + + A
Sbjct: 955 PISRNTFAEVTGLS-PGVTYYFKVFA---LSHGRESKPLTAQQTTKLDA 999
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1995 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 2046
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 2086
>AC012462-1|AAX76513.1| 2217|Homo sapiens unknown protein.
Length = 2217
Score = 89.8 bits (213), Expect = 5e-17
Identities = 155/685 (22%), Positives = 255/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1359 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1413
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1414 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1468
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1469 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1509
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1564
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1565 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1623 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1671
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1672 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1729
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1730 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1790 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 1841
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1842 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1900
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1901 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 1955 VTEA-TITGLEPGTEYTIYVIALKN 1978
Score = 61.7 bits (143), Expect = 1e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 760
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 761 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 816
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 817 TTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 860
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 918
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 919 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 971
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 972 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1024
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1025 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1131
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1132 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 998 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1051
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1052 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1107
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1108 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1144
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1196
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1253
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1254 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1308
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1366
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1367 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1421 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1477
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1589
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1624
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/386 (20%), Positives = 146/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 622 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 677
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 735
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L +K+ +V
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY-----IVNV 790
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
Y P PP + + S+ V W P + GYR+
Sbjct: 791 YQI-SEDGEQSLILSTSQTTAPDAPPDTT-VDQVDDTSIVVRWSRP-----QAPITGYRI 843
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 844 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 898
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 899 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 954
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 955 PISRNTFAEVTGLS-PGVTYYFKVFA 979
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1904 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 1955
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 1995
>X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein.
Length = 1451
Score = 89.4 bits (212), Expect = 6e-17
Identities = 111/511 (21%), Positives = 203/511 (39%), Gaps = 46/511 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP P ++ V + + +SW P G+ I+ ++ + + E+W ++ P
Sbjct: 500 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTEL--PVKS 557
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSGPPQDVRVEAKSST 184
++ +L SY R+ N G EPS+ +VT ++P P + + + T
Sbjct: 558 PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK-IIPSRNTDT 616
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++V+WE +D ++GYY+ S + P V+T R
Sbjct: 617 SVVVSWE-ESKDA--KELVGYYIEANVAGSGKWEPCNNNP------VKT--------HRF 659
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED--VPSLPPGALQCNALSSQSVRV 302
T GL +Y V+A N+ ++ P PP + C S+ +
Sbjct: 660 TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVL 719
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYSVTV 360
W+ P G + GY V Y V D + +A K + +S L+ Y V
Sbjct: 720 GWKQPDKTG-GAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQV 778
Query: 361 CAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSSRNKILVSWLPP-SSPNGVLV 415
A AG G +A C E+ VP P +K + ++ +++ W PP S +
Sbjct: 779 AAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVT 838
Query: 416 GYTLYMSVIEDGREEGTHKRMLSPSTLSH---ETSRSPPRATHQFWVSASTRLGEGEATR 472
GY ++ + E +E+ R L+ + + + + ++ F V A + G G+ +
Sbjct: 839 GY--FVDLKEKAKED--QWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSD 894
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV 532
+ + +++ P R N+ +++ C+K+ P +W+ + V E + R V
Sbjct: 895 LAGPVVAETRPGR-KEVVVNVDDDGVISLNFECDKM-TPKSEFSWSKDYVSTEDSPRLEV 952
Query: 533 SSDGT---LTISMTQSADSGNYTCSVENIHG 560
S G +T D G Y+C V + G
Sbjct: 953 ESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 983
Score = 80.6 bits (190), Expect = 3e-14
Identities = 101/404 (25%), Positives = 160/404 (39%), Gaps = 44/404 (10%)
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPS--SPNGVLVGYTLYMSVIEDGREEGTHKRM 436
+E VP P D+ ++R+ +++SW PP G++ + E+ + T +
Sbjct: 496 SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPV 555
Query: 437 LSPSTLSHETSRSPPRATHQFWVSASTRLGEG---EATRVVTV--------LPSDSVPAR 485
SP + + ++ F V S G G EAT V V P +P+R
Sbjct: 556 KSPRFALFDLAEG---KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSR 612
Query: 486 ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
T S +V W+E+ VG A + G G N T +
Sbjct: 613 NTDTS--VVVSWEESKDAK-ELVGYYIEA---NVAGSGKWEPCNNNPVKTHRFTCHGLVT 666
Query: 546 ADSGNYTCSVENIHGRDEVTY---TVEVK---VPPQPPI-LAVVDSYADSLHLQWSD-QG 597
S + N G E + +EVK PP PP + ++S+ DS+ L W
Sbjct: 667 GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDK 726
Query: 598 DGGSPILGYVINYKR----EHGDWEELQVEAGTSE-HVLPNLWCGTRYQLYITAFNRIGT 652
GG+ I GY +NY+ G W E V+A E + + NL YQ + A N G
Sbjct: 727 TGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVAAMNMAGL 786
Query: 653 GLPCDIVHAY--TKGTVPVK-PKHSQMIT--LNTTTVTVWLDSWGDGGCGILYFVIEYRE 707
G P + + + T+ V P HS + + V W G + + ++ +E
Sbjct: 787 GAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKE 846
Query: 708 MS-QPQWRLVSNSVQATERVF-SVSGLTPAAHYQLRITAHNNAG 749
+ + QWR ++ + A + V+ V GL Y R+ A N AG
Sbjct: 847 KAKEDQWRGLNEA--AIKNVYLKVRGLKEGVSYVFRVRAINQAG 888
Score = 60.5 bits (140), Expect = 3e-08
Identities = 125/548 (22%), Positives = 200/548 (36%), Gaps = 57/548 (10%)
Query: 167 EVPSGP--PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNS-------T 217
E+ P P DV+ + +I++W+ P D ILGY++ E+ ++S
Sbjct: 369 EIEGAPAAPLDVKCLEANKDYIIISWKQPAVD-GGSPILGYFIDKCEVGTDSWSQCNDTP 427
Query: 218 VLIASGP-----GGASYT--VRTVEGAGTA-RSRTTLSGLQKHAAYAVVVQAYNSRXXXX 269
V A P G SY VR V G SR + + A +++ S
Sbjct: 428 VKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWT 487
Query: 270 XXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW 329
VP PP L + V +SW+PP RG GI+ A +W
Sbjct: 488 VIVTEEEPSEGIVPG-PPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENW 546
Query: 330 YGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV--RAAPVYCHTEE-DVPSA 386
+ + L L +Y V +AG G A V ++ D+P A
Sbjct: 547 QRVNTELP--VKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKA 604
Query: 387 PADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHK------RMLSPS 440
P I + ++ ++VSW S LVGY + +V G+ E + R
Sbjct: 605 PGKIIPSRNTDTSVVVSW-EESKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHG 663
Query: 441 TLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARIT---SFSRNIVTPW 497
++ ++ RA + +S ++ + EA V + S P IT SF ++V W
Sbjct: 664 LVTGQSYIFRVRAVNAAGLSEYSQ--DSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGW 721
Query: 498 KENISLSCNKV------------GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
K+ ++ GVP + V E+ N+ + +
Sbjct: 722 KQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVAAM 781
Query: 546 ADSG-NYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGG-SPI 603
+G +V +E T + VP P L + DSL LQW G +P+
Sbjct: 782 NMAGLGAPSAVSECFKCEEWT----IAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPV 837
Query: 604 LGYVINYKRE--HGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIVH 660
GY ++ K + W L A + ++ + L G Y + A N+ G G P D+
Sbjct: 838 TGYFVDLKEKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAG 897
Query: 661 AYTKGTVP 668
T P
Sbjct: 898 PVVAETRP 905
Score = 60.1 bits (139), Expect = 4e-08
Identities = 105/433 (24%), Positives = 155/433 (35%), Gaps = 43/433 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P P +++ ++ I ISW QP G SPI+ Y + E +SW P
Sbjct: 374 PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCND---TPVKF 430
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST--- 184
V L SY R+ A N++G PS+ + + P + R+++ ST
Sbjct: 431 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEAVAALD----PAEKARLKSPLSTLDW 486
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG-----GASYTVRTVEGAGT 239
+IVT E P + G V E + VL PG G Y V E AGT
Sbjct: 487 TVIVTEEEPSEGIVPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCE-AGT 543
Query: 240 AR------------SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP- 286
R L L + +Y V+ NS + D +P
Sbjct: 544 ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPK 603
Query: 287 -PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
PG + + + SV VSWE L GY + A V E +
Sbjct: 604 APGKIIPSRNTDTSVVVSWEESKDAKE---LVGYYIE-ANVAGSGKWEPCNNNPVKTHRF 659
Query: 346 TLSGLRRYTNYSVTVCAFTAAG---DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
T GL +Y V A AAG + + PS P DI S R+ +++
Sbjct: 660 TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVL 719
Query: 403 SWLPPSSPNGV-LVGYTL-YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
W P G + GY + Y VI+ + + + +++ S +QF V+
Sbjct: 720 GWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVA 779
Query: 461 ASTRLGEGEATRV 473
A G G + V
Sbjct: 780 AMNMAGLGAPSAV 792
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 484 ARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLEST----LRKNVSSDGTL 538
AR+ ++VT + + ++L+CN G P P +W N L T L+
Sbjct: 1338 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYF 1397
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
TI+ +ADSG Y V+N +G + +TV V +P + +A ++S
Sbjct: 1398 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1443
Score = 47.6 bits (108), Expect = 2e-04
Identities = 56/207 (27%), Positives = 82/207 (39%), Gaps = 22/207 (10%)
Query: 499 ENISLSCNKVGVPA-----PATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGN 550
E +SL C V P P W NGV L + G TLT S D G
Sbjct: 284 ETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 343
Query: 551 YTCSVENIHGRDEVTYTV-------EVKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGS 601
YT V ++ + V E++ P P+ + +++ D + + W DGGS
Sbjct: 344 YTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGS 403
Query: 602 PILGYVINYKREHG--DWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
PILGY I+ K E G W + + + L G Y + A N++G G P +
Sbjct: 404 PILGYFID-KCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRV 462
Query: 659 VHAYTKGTVPVKPK-HSQMITLNTTTV 684
A K + S + TL+ T +
Sbjct: 463 SEAVAALDPAEKARLKSPLSTLDWTVI 489
Score = 35.9 bits (79), Expect = 0.80
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 495 TPW-KENISLSCNKVGVPAPATTWTMNGV--GLESTLRKNV--SSDG--TLTISMTQSAD 547
T W KEN+ L C+ G P P TW N V + + K + S G TL I+ D
Sbjct: 151 TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINACDFED 210
Query: 548 SGNYTCSVENIHGRDEVTYTVEVK 571
+ Y S N+ G +V VK
Sbjct: 211 TAQYRASAMNVKGELSAYASVVVK 234
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 89.4 bits (212), Expect = 6e-17
Identities = 81/314 (25%), Positives = 129/314 (41%), Gaps = 28/314 (8%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPST 117
R+ +L P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W
Sbjct: 619 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 678
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDV 176
+ PGSV SA V L P +Y R+IA N +G S PS P + T+ P P DV
Sbjct: 679 SK---YPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 734
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ E + +TW P G L Y V ++ + ++ TV G
Sbjct: 735 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG 783
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
SR + + Y + VQA N ED+PS P + +
Sbjct: 784 -----SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPN 837
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTN 355
+++ + W+ P NGI+ GY + Y G + + T+ +
Sbjct: 838 LETINLEWDHP--EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 895
Query: 356 YSVTVCAFTAAGDG 369
Y T+ A T G G
Sbjct: 896 YRFTLSARTQVGSG 909
Score = 67.7 bits (158), Expect = 2e-10
Identities = 57/212 (26%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y Y + V A G G V ++ ED+PSAP + + I + W P PNG
Sbjct: 794 YVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNG 853
Query: 413 VLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA- 470
+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 854 IMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV 912
Query: 471 TRVVTVLPSDSVP-ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL- 528
T P+++ P A + V S + ATT + +T+
Sbjct: 913 TEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTTIA 972
Query: 529 -RKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
V++ T T + T + +S T S IH
Sbjct: 973 TTTTVATTTTTTAAATTTTESPPTTTSGTKIH 1004
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 386 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 440
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 441 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 500
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 501 CVATNILGKAENQVRLEVKDP 521
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/131 (25%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
IG +P P+ RV TI + W P N +I Y ++Y +
Sbjct: 817 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 876
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSE------PSQPVQVTTTEEVPSGPPQD 175
+ T +VQ P + Y + A ++G E P+ P + T T P+ PP
Sbjct: 877 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTT 936
Query: 176 V-RVEAKSSTE 185
V A SST+
Sbjct: 937 VGATGAVSSTD 947
Score = 43.6 bits (98), Expect = 0.004
Identities = 62/297 (20%), Positives = 106/297 (35%), Gaps = 16/297 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
P L+ L+ +SVR++W P N + Y V + G +K +++
Sbjct: 631 PRDLELTDLAERSVRLTWIPGD--ANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA 688
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVP--SAPADIKAAVSSRNKILVSW 404
+ L Y NY V A G + P + P S P D+K + +N + ++W
Sbjct: 689 VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 748
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
P ++ + G L V RE ++ + ++P ++ V A
Sbjct: 749 TPMNATSA--FGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAEND 806
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSC------NKVGVPAPATTWT 518
G+G V + +P+ F + P E I+L N + +
Sbjct: 807 FGKGPEPESVIGYSGEDLPSAPRRF--RVRQPNLETINLEWDHPEHPNGIMIGYTLKYVA 864
Query: 519 MNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
NG + + +N S + T T+ T +T S G E T E PP
Sbjct: 865 FNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV-TEESPAPP 920
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 263 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 322
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 323 GSIRHTISVRVKAAP 337
Score = 40.3 bits (90), Expect = 0.037
Identities = 65/294 (22%), Positives = 101/294 (34%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 521 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 579
Query: 541 SMTQSADSGNYTCSVENIHGRD-----------EVTYTVEVKV-----PPQPPILAVVDS 584
D G+YTC +D + T T + P +P L + D
Sbjct: 580 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 639
Query: 585 YADSLHLQWSDQGDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQ 641
S+ L W SPI YV+ ++ + G W + G+ + L YQ
Sbjct: 640 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQ 699
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGC 696
+ A N +G+ P Y P + + T W +++ G
Sbjct: 700 FRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGP 759
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
+ Y V R ++ W N+V + V G TP Y++R+ A N+ G
Sbjct: 760 NLRYIVKWRRRETREAW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 808
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 402
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
Score = 35.5 bits (78), Expect = 1.1
Identities = 36/221 (16%), Positives = 73/221 (33%), Gaps = 1/221 (0%)
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
P L Y++ ++R V S +V+ Y++ + A N G G + V
Sbjct: 759 PNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIG 818
Query: 662 YTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQ-WRLVSNSV 720
Y+ +P P+ ++ N T+ + D ++ + ++Y + + + + +
Sbjct: 819 YSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF 878
Query: 721 QATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXPPIPAAGAR 780
+ F+V P + Y+ ++A G A+ + P +P
Sbjct: 879 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVG 938
Query: 781 SLGGARXXXXXXXXXXXXXXXXXXXXXXKRNKTGTTETVAT 821
+ G TT TVAT
Sbjct: 939 ATGAVSSTDATAIAATTEATTVPIIPTVAPTTIATTTTVAT 979
Score = 33.5 bits (73), Expect = 4.3
Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGT-HKRMLSPSTL 442
P P D++ + + ++W+P + N + Y + ED + G H P ++
Sbjct: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFE--EDQFQPGVWHDHSKYPGSV 685
Query: 443 SHETSRSPPRATHQFWVSASTRLG 466
+ R P +QF V A +G
Sbjct: 686 NSAVLRLSPYVNYQFRVIAINEVG 709
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 89.4 bits (212), Expect = 6e-17
Identities = 81/314 (25%), Positives = 129/314 (41%), Gaps = 28/314 (8%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPST 117
R+ +L P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W
Sbjct: 588 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 647
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDV 176
+ PGSV SA V L P +Y R+IA N +G S PS P + T+ P P DV
Sbjct: 648 SK---YPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 703
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ E + +TW P G L Y V ++ + ++ TV G
Sbjct: 704 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG 752
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
SR + + Y + VQA N ED+PS P + +
Sbjct: 753 -----SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPN 806
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTN 355
+++ + W+ P NGI+ GY + Y G + + T+ +
Sbjct: 807 LETINLEWDHP--EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 864
Query: 356 YSVTVCAFTAAGDG 369
Y T+ A T G G
Sbjct: 865 YRFTLSARTQVGSG 878
Score = 66.9 bits (156), Expect = 4e-10
Identities = 45/146 (30%), Positives = 70/146 (47%), Gaps = 4/146 (2%)
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y Y + V A G G V ++ ED+PSAP + + I + W P PNG
Sbjct: 763 YVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNG 822
Query: 413 VLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA- 470
+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 823 IMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV 881
Query: 471 TRVVTVLPSDSVP-ARITSFSRNIVT 495
T P+++ P A T+ +I T
Sbjct: 882 TEESPAPPNEATPTAAYTNNQADIAT 907
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 355 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 409
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 410 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 469
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 470 CVATNILGKAENQVRLEVKDP 490
Score = 46.4 bits (105), Expect = 6e-04
Identities = 67/318 (21%), Positives = 113/318 (35%), Gaps = 18/318 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
P L+ L+ +SVR++W P N + Y V + G +K +++
Sbjct: 600 PRDLELTDLAERSVRLTWIPGD--ANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA 657
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVP--SAPADIKAAVSSRNKILVSW 404
+ L Y NY V A G + P + P S P D+K + +N + ++W
Sbjct: 658 VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 717
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
P ++ + G L V RE ++ + ++P ++ V A
Sbjct: 718 TPMNATSA--FGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAEND 775
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSC------NKVGVPAPATTWT 518
G+G V + +P+ F + P E I+L N + +
Sbjct: 776 FGKGPEPESVIGYSGEDLPSAPRRF--RVRQPNLETINLEWDHPEHPNGIMIGYTLKYVA 833
Query: 519 MNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ-- 575
NG + + +N S + T T+ T +T S G E T E PP
Sbjct: 834 FNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV-TEESPAPPNEA 892
Query: 576 PPILAVVDSYADSLHLQW 593
P A ++ AD W
Sbjct: 893 TPTAAYTNNQADIATQGW 910
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 232 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 291
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 292 GSIRHTISVRVKAAP 306
Score = 40.3 bits (90), Expect = 0.037
Identities = 65/294 (22%), Positives = 101/294 (34%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 490 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 548
Query: 541 SMTQSADSGNYTCSVENIHGRD-----------EVTYTVEVKV-----PPQPPILAVVDS 584
D G+YTC +D + T T + P +P L + D
Sbjct: 549 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 608
Query: 585 YADSLHLQWSDQGDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQ 641
S+ L W SPI YV+ ++ + G W + G+ + L YQ
Sbjct: 609 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQ 668
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGC 696
+ A N +G+ P Y P + + T W +++ G
Sbjct: 669 FRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGP 728
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
+ Y V R ++ W N+V + V G TP Y++R+ A N+ G
Sbjct: 729 NLRYIVKWRRRETREAW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 777
Score = 38.7 bits (86), Expect = 0.11
Identities = 28/124 (22%), Positives = 46/124 (37%), Gaps = 7/124 (5%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
IG +P P+ RV TI + W P N +I Y ++Y +
Sbjct: 786 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 845
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
+ T +VQ P + Y + A ++G E TEE P+ P + A
Sbjct: 846 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPAPPNEATPTAAY 898
Query: 182 SSTE 185
++ +
Sbjct: 899 TNNQ 902
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 313 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 371
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 372 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 400
Score = 33.5 bits (73), Expect = 4.3
Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGT-HKRMLSPSTL 442
P P D++ + + ++W+P + N + Y + ED + G H P ++
Sbjct: 597 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFE--EDQFQPGVWHDHSKYPGSV 654
Query: 443 SHETSRSPPRATHQFWVSASTRLG 466
+ R P +QF V A +G
Sbjct: 655 NSAVLRLSPYVNYQFRVIAINEVG 678
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 89.4 bits (212), Expect = 6e-17
Identities = 81/314 (25%), Positives = 129/314 (41%), Gaps = 28/314 (8%)
Query: 61 RIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKE---APESWPST 117
R+ +L P+ P+++ + D R+++++W A NSPI +Y+VQ++E P W
Sbjct: 619 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 678
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDV 176
+ PGSV SA V L P +Y R+IA N +G S PS P + T+ P P DV
Sbjct: 679 SK---YPGSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 734
Query: 177 RVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ E + +TW P G L Y V ++ + ++ TV G
Sbjct: 735 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE-----------AWNNVTVWG 783
Query: 237 AGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
SR + + Y + VQA N ED+PS P + +
Sbjct: 784 -----SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPN 837
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTN 355
+++ + W+ P NGI+ GY + Y G + + T+ +
Sbjct: 838 LETINLEWDHP--EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 895
Query: 356 YSVTVCAFTAAGDG 369
Y T+ A T G G
Sbjct: 896 YRFTLSARTQVGSG 909
Score = 67.7 bits (158), Expect = 2e-10
Identities = 57/212 (26%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y Y + V A G G V ++ ED+PSAP + + I + W P PNG
Sbjct: 794 YVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNG 853
Query: 413 VLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA- 470
+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 854 IMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV 912
Query: 471 TRVVTVLPSDSVP-ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL- 528
T P+++ P A + V S + ATT + +T+
Sbjct: 913 TEESPAPPNEATPTAAPPTLPPTTVGATGAVSSTDATAIAATTEATTVPIIPTVAPTTIA 972
Query: 529 -RKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
V++ T T + T + +S T S IH
Sbjct: 973 TTTTVATTTTTTAAATTTTESPPTTTSGTKIH 1004
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
R ++ T+ ++ RA +Q + S G A V+VL VP R+ S ++
Sbjct: 386 REVAGDTIIFRDTQISSRAVYQ--CNTSNEHGYLLANAFVSVL---DVPPRMLSPRNQLI 440
Query: 495 TPWKENIS-LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYT 552
N + L C G P P W NG G +V +G+L I M + D G YT
Sbjct: 441 RVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT 500
Query: 553 CSVENIHGRDEVTYTVEVKVP 573
C NI G+ E +EVK P
Sbjct: 501 CVATNILGKAENQVRLEVKDP 521
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/131 (25%), Positives = 51/131 (38%), Gaps = 7/131 (5%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
IG +P P+ RV TI + W P N +I Y ++Y +
Sbjct: 817 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 876
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSE------PSQPVQVTTTEEVPSGPPQD 175
+ T +VQ P + Y + A ++G E P+ P + T T P+ PP
Sbjct: 877 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTT 936
Query: 176 V-RVEAKSSTE 185
V A SST+
Sbjct: 937 VGATGAVSSTD 947
Score = 43.6 bits (98), Expect = 0.004
Identities = 62/297 (20%), Positives = 106/297 (35%), Gaps = 16/297 (5%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
P L+ L+ +SVR++W P N + Y V + G +K +++
Sbjct: 631 PRDLELTDLAERSVRLTWIPGD--ANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA 688
Query: 347 LSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVP--SAPADIKAAVSSRNKILVSW 404
+ L Y NY V A G + P + P S P D+K + +N + ++W
Sbjct: 689 VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 748
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
P ++ + G L V RE ++ + ++P ++ V A
Sbjct: 749 TPMNATSA--FGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAEND 806
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSC------NKVGVPAPATTWT 518
G+G V + +P+ F + P E I+L N + +
Sbjct: 807 FGKGPEPESVIGYSGEDLPSAPRRF--RVRQPNLETINLEWDHPEHPNGIMIGYTLKYVA 864
Query: 519 MNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
NG + + +N S + T T+ T +T S G E T E PP
Sbjct: 865 FNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV-TEESPAPP 920
Score = 43.2 bits (97), Expect = 0.005
Identities = 25/75 (33%), Positives = 31/75 (41%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
++ L C GVP P W G L S K + + L I+ DSG Y C N
Sbjct: 263 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 322
Query: 560 GRDEVTYTVEVKVPP 574
G T +V VK P
Sbjct: 323 GSIRHTISVRVKAAP 337
Score = 40.3 bits (90), Expect = 0.037
Identities = 65/294 (22%), Positives = 101/294 (34%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLESTLRKNVSSDGTLTI 540
P RI + V + L C P+ T W + L R D +LTI
Sbjct: 521 PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTI 579
Query: 541 SMTQSADSGNYTCSVENIHGRD-----------EVTYTVEVKV-----PPQPPILAVVDS 584
D G+YTC +D + T T + P +P L + D
Sbjct: 580 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 639
Query: 585 YADSLHLQWSDQGDGGSPILGYVINYKREH---GDWEELQVEAGTSEHVLPNLWCGTRYQ 641
S+ L W SPI YV+ ++ + G W + G+ + L YQ
Sbjct: 640 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQ 699
Query: 642 LYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMI---TLNTTTVTVW--LDSWGDGGC 696
+ A N +G+ P Y P + + T W +++ G
Sbjct: 700 FRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGP 759
Query: 697 GILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPA-AHYQLRITAHNNAG 749
+ Y V R ++ W N+V + V G TP Y++R+ A N+ G
Sbjct: 760 NLRYIVKWRRRETREAW----NNVTVWGSRY-VVGQTPVYVPYEIRVQAENDFG 808
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES---TLRKNVSSDGTLTISMTQSAD 547
+N++ E+ L C G P P W +NG L+S + V+ D T+ TQ +
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISS 402
Query: 548 SGNYTCSVENIHGRDEVTYTVEV-KVPPQ 575
Y C+ N HG V V VPP+
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDVPPR 431
Score = 35.5 bits (78), Expect = 1.1
Identities = 36/221 (16%), Positives = 73/221 (33%), Gaps = 1/221 (0%)
Query: 602 PILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
P L Y++ ++R V S +V+ Y++ + A N G G + V
Sbjct: 759 PNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIG 818
Query: 662 YTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQ-WRLVSNSV 720
Y+ +P P+ ++ N T+ + D ++ + ++Y + + + + +
Sbjct: 819 YSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF 878
Query: 721 QATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTTHXXXXXXXXXXXPPIPAAGAR 780
+ F+V P + Y+ ++A G A+ + P +P
Sbjct: 879 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLPPTTVG 938
Query: 781 SLGGARXXXXXXXXXXXXXXXXXXXXXXKRNKTGTTETVAT 821
+ G TT TVAT
Sbjct: 939 ATGAVSSTDATAIAATTEATTVPIIPTVAPTTIATTTTVAT 979
Score = 33.5 bits (73), Expect = 4.3
Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGT-HKRMLSPSTL 442
P P D++ + + ++W+P + N + Y + ED + G H P ++
Sbjct: 628 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFE--EDQFQPGVWHDHSKYPGSV 685
Query: 443 SHETSRSPPRATHQFWVSASTRLG 466
+ R P +QF V A +G
Sbjct: 686 NSAVLRLSPYVNYQFRVIAINEVG 709
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 89.0 bits (211), Expect = 8e-17
Identities = 81/365 (22%), Positives = 146/365 (40%), Gaps = 31/365 (8%)
Query: 65 LSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP 124
+S P P N+ S I ++W +P + +I Y V Y +A E + +V++
Sbjct: 414 MSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKA-EGLNNEEYQVVIG 472
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
T + +L+PA++Y I+A +G S+ S V T E+VP PP ++ + ++S T
Sbjct: 473 NDTTHYIIDDLEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPP-EISLTSRSPT 531
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+++++W P G ++ Y + F+ NS ++ +E GT
Sbjct: 532 DILISWLPIPAKYRRGQVVLYRLSFRLSTENS--------------IQVLELPGTTH-EY 576
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA--LQCNALSSQSVRV 302
L GL+ + Y V + A + P + L L+ ++ V
Sbjct: 577 LLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISV 636
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
W+ +QGY++ Y + + L TLSGL Y V + A
Sbjct: 637 RWQQDV--EDTAAIQGYKLYYK--EEGQQENGPIFLDTKDLLYTLSGLDPRRKYHVRLLA 692
Query: 363 FTAAGDGVRAAPVY----CHTEED----VPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
+ DG +A C + D P P + A ++ + I + W P+ +
Sbjct: 693 YNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTAAQI 752
Query: 415 VGYTL 419
+ YT+
Sbjct: 753 INYTI 757
Score = 73.7 bits (173), Expect = 3e-12
Identities = 61/276 (22%), Positives = 113/276 (40%), Gaps = 12/276 (4%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P + ++ P C G+P+P +W NG + S R + + L I+
Sbjct: 326 PPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNS-KLVINQ 384
Query: 543 TQSADSGNYTCSVENIHG----RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGD 598
D Y C EN G R +T + P P + + ++ L W
Sbjct: 385 IIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLY 444
Query: 599 GGSPILGYVINYKREHG-DWEELQVEAG--TSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
++ Y ++Y + G + EE QV G T+ +++ +L + Y YI A+ +G
Sbjct: 445 NSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPMGASQM 504
Query: 656 CDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCG-ILYFVIEYREMSQPQW 713
D V T VP++P + + + T + + WL G ++ + + +R ++
Sbjct: 505 SDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSI 564
Query: 714 RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+++ + T + + GL P + Y +RITA G
Sbjct: 565 QVL--ELPGTTHEYLLEGLKPDSVYLVRITAATRVG 598
Score = 69.7 bits (163), Expect = 5e-11
Identities = 128/601 (21%), Positives = 221/601 (36%), Gaps = 67/601 (11%)
Query: 89 SWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV----TSASVQNLQPATSYHLR 144
S T+P AG + + SW +K+ G + + + + P +
Sbjct: 335 SLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQIIPEDDAIYQ 394
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN-IL 203
+AEN G + V +E+ PS P +V E SS+ +++ WE P L+N + ++
Sbjct: 395 CMAENSQGSILSRARLTVVMSEDRPSAP-YNVHAETMSSSAILLAWERP---LYNSDKVI 450
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y V + + A G Y V V G T + + L+ + Y + AY
Sbjct: 451 AYSVHYMK---------AEGLNNEEYQV--VIGNDT--THYIIDDLEPASNYTFYIVAYM 497
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
+EDVP PP + + S + +SW P P + R G + YR+++
Sbjct: 498 PMGASQMSDHVTQNTLEDVPLRPP-EISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSF 556
Query: 324 APVTDWYGNEDAVTKQISGLHT-TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
T+ N V + H L GL+ + Y V + A T G G + T +
Sbjct: 557 RLSTE---NSIQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKA 613
Query: 383 VP-SAPADIKAAVSSRN--KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
AP + + N I V W + GY LY E+G++E L
Sbjct: 614 TSVKAPKSPELHLEPLNCTTISVRWQQDVEDTAAIQGYKLYYK--EEGQQE-NGPIFLDT 670
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEG-EATRVVT----------VLPSDSVPARI-- 486
L + S PR + + A + +G +A + V+ ++P P +
Sbjct: 671 KDLLYTLSGLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYA 730
Query: 487 -TSFSRNIVTPWKE---------NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG 536
+ S +I W+ N ++ CN VG+ + + L + + +
Sbjct: 731 KANTSSSIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLVLYLQ-TSETHMLVQGLEPNT 789
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQ 596
++ D + S H T PP + +++ D+ + W
Sbjct: 790 KYEFAVRLHVDQLSSPWSPVVYHS----TLPEAPAGPPVGVKVTLIED--DTALVSWKPP 843
Query: 597 GDGGSPILGYVINYKREH----GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGT 652
+ + Y I Y G+W+ L E + +L NL G Y + I+A N +G
Sbjct: 844 DGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGE 903
Query: 653 G 653
G
Sbjct: 904 G 904
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P P ++ S +I + W +P + IINY ++ P + + + S T
Sbjct: 722 PPPPHHLYAKANTSSSIFLHWRRPAFTAAQIINYTIRCN--PVGLQNASLVLYLQTSETH 779
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
VQ L+P T Y + S S V +T E P+GPP V+V +V+
Sbjct: 780 MLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVS 839
Query: 190 WEPP 193
W+PP
Sbjct: 840 WKPP 843
Score = 47.2 bits (107), Expect = 3e-04
Identities = 46/193 (23%), Positives = 85/193 (44%), Gaps = 10/193 (5%)
Query: 562 DEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD---QGDGGSPILGYVINYKRE-HGDW 617
D VT VP +PP +++ + + W + G +L Y ++++
Sbjct: 506 DHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVL-YRLSFRLSTENSI 564
Query: 618 EELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV-HAYTKGTVPVKPKHSQM 676
+ L++ T E++L L + Y + ITA R+G G H K T PK ++
Sbjct: 565 QVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPEL 624
Query: 677 IT--LNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
LN TT++V + I + + Y+E Q + + + + ++++SGL P
Sbjct: 625 HLEPLNCTTISVRWQQDVEDTAAIQGYKLYYKEEGQQENGPIF--LDTKDLLYTLSGLDP 682
Query: 735 AAHYQLRITAHNN 747
Y +R+ A+NN
Sbjct: 683 RRKYHVRLLAYNN 695
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT-----QS 545
+++ K+ + L C G TW NG + R V S+G+L IS +
Sbjct: 46 QDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVEGRRGEQ 105
Query: 546 ADSGNYTCSVENIHG 560
+D G Y C N +G
Sbjct: 106 SDEGFYQCLAMNKYG 120
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/95 (31%), Positives = 36/95 (37%), Gaps = 8/95 (8%)
Query: 504 SCNKVGVPAPATTWTMNGVGLESTL-RKNVSSDGTLTISMTQSADSGNYTCSVENI-HGR 561
+C P TW N L T+ R G L I DSGNY C + H R
Sbjct: 155 ACKISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRR 214
Query: 562 D--EVTYTV----EVKVPPQPPILAVVDSYADSLH 590
E + TV E K P I+A + SLH
Sbjct: 215 KSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLH 249
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/63 (26%), Positives = 25/63 (39%)
Query: 491 RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
+NI T + + L C G P P +W+ V +G L IS + +G
Sbjct: 242 QNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLMISDVRLQHAGV 301
Query: 551 YTC 553
Y C
Sbjct: 302 YVC 304
>BX640731-1|CAE45847.1| 2444|Homo sapiens hypothetical protein
protein.
Length = 2444
Score = 88.6 bits (210), Expect = 1e-16
Identities = 152/684 (22%), Positives = 256/684 (37%), Gaps = 71/684 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1448 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1502
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1503 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1557
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1558 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1598
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1599 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1653
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ GL+ Y V+V A +G+
Sbjct: 1654 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1711
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1712 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1760
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA----RI 486
G H+ +P R ++ VS + E+ ++ S ++PA +
Sbjct: 1761 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAPADLKF 1819
Query: 487 TSFS-RNIVTPW-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQ 544
T + ++ W N+ L+ +V V T M + L V S +
Sbjct: 1820 TQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV 1879
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPIL 604
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1880 SVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TIT 1931
Query: 605 GYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A T
Sbjct: 1932 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAST 1990
Query: 664 KGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQAT 723
P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1991 AIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2044
Query: 724 ERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 2045 TEA-TITGLEPGTEYTIYVIALKN 2067
Score = 61.7 bits (143), Expect = 1e-08
Identities = 149/695 (21%), Positives = 248/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V SV+
Sbjct: 1087 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSVSKY 1140
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1141 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1196
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G+ +SGL
Sbjct: 1197 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSGS------IVVSGLT 1233
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1234 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1285
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1286 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1342
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1343 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1397
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1398 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1455
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1456 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1509
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1510 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1566
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1567 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1626
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1627 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1678
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ GL P Y + + A N +G + L
Sbjct: 1679 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1713
Score = 60.9 bits (141), Expect = 2e-08
Identities = 127/596 (21%), Positives = 218/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 795 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 849
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 850 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 905
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 906 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 949
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 950 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 1007
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 1008 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 1060
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 1061 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1113
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1114 TGYRLTVGLTRRGQ---PRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1170
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1171 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1220
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G++ +S YT V + +V P PP +++ D+ L
Sbjct: 1221 TSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1280
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1281 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1336
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 711 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 766
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 767 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 824
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 825 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 881
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 882 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 932
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 933 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 987
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 988 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 1043
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 1044 PISRNTFAEVTGLS-PGVTYYFKVFA 1068
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1993 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 2044
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 2045 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 2084
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 87.8 bits (208), Expect = 2e-16
Identities = 100/430 (23%), Positives = 170/430 (39%), Gaps = 35/430 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
VP + + I+++W P N ++ Y ++Y E + + V G+
Sbjct: 526 VPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTE---VRGN 582
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT-----TEEVPSGPPQDVRVEAK 181
T + +LQP Y +RI A G PSQ + T VP P +++V+AK
Sbjct: 583 ETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFA-PAELKVQAK 641
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV---LIASGPGGASYTVRTVEGAG 238
+ L+V+W+PP I GY + ++E+ + + G G ++ V V
Sbjct: 642 MES-LVVSWQPPPHPT---QISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKK 697
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX--------MEDVPSLPPGAL 290
+ + L+ L Y V + A+N ++ P LPP +
Sbjct: 698 KVK-QYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHV 756
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQI-SGLHTTLS 348
+ SS S+ + W+ P + Y V ++P W N VT SG +
Sbjct: 757 HAESNSSTSIWLRWKKPDFTTVK--IVNYTVRFSP---WGLRNASLVTYYTSSGEDILIG 811
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP 407
GL+ +T Y V + DG + V T D PS P+D++ + + + + + W PP
Sbjct: 812 GLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPP 871
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
+ PNG +V Y + S E + S E + F + A T +G
Sbjct: 872 TEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGP 931
Query: 468 GEATRVVTVL 477
G +R+ V+
Sbjct: 932 GPFSRLQDVI 941
Score = 85.8 bits (203), Expect = 8e-16
Identities = 82/319 (25%), Positives = 137/319 (42%), Gaps = 34/319 (10%)
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+V V G S + + + + + +AEN G + + + V E +PS P + V
Sbjct: 380 RVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTR-VTAT 438
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
SS+ ++V WE P ++ + I+G+ + +Q+ A G Y
Sbjct: 439 PLSSSAVLVAWERP--EMHSEQIIGFSLHYQK---------ARGMDNVEYQF----AVNN 483
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
+ + L+ + Y V AY+ ++DVPS P L ++ +
Sbjct: 484 DTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAP-QLSLSSPNPSD 542
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV-TKQISGLHT--TLSGLRRYTNY 356
+RV+W P P NG + Y++ Y G ED + + ++ G T L+ L+ Y
Sbjct: 543 IRVAWLPLPPSLSNGQVVKYKIEYG-----LGKEDQIFSTEVRGNETQLMLNSLQPNKVY 597
Query: 357 SVTVCAFTAAGDGVRAAPVY-----CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
V + A TAAG G + ++ H + VP APA++K + ++VSW PP P
Sbjct: 598 RVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQ-AKMESLVVSWQPPPHPT 656
Query: 412 GVLVGYTLYMSVIEDGREE 430
+ GY LY E G EE
Sbjct: 657 QI-SGYKLYWR--EVGAEE 672
Score = 72.5 bits (170), Expect = 8e-12
Identities = 59/244 (24%), Positives = 104/244 (42%), Gaps = 22/244 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
+P P + S + ++W +P + II + + Y++A + + V T
Sbjct: 428 LPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKA-RGMDNVEYQFAVNNDTT 486
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V++L+P T Y ++A ++LG S S P V T ++VPS PQ + + + + +++ V
Sbjct: 487 ELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQ-LSLSSPNPSDIRV 545
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W P L NG ++ Y + + G G T E G ++ L+
Sbjct: 546 AWLPLPPSLSNGQVVKYKIEY-------------GLGKEDQIFST-EVRGN-ETQLMLNS 590
Query: 249 LQKHAAYAVVVQAYNSRXXXXXX--XXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSW 304
LQ + Y V + A + M + +P P L+ A +S+ VSW
Sbjct: 591 LQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQA-KMESLVVSW 649
Query: 305 EPPP 308
+PPP
Sbjct: 650 QPPP 653
Score = 71.3 bits (167), Expect = 2e-11
Identities = 64/255 (25%), Positives = 105/255 (41%), Gaps = 12/255 (4%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSADSGNYTCSVENIHG--- 560
C G P PA W NG L R V G+L I+ D+G Y C EN G
Sbjct: 356 CRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMAC 415
Query: 561 -RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHG-DWE 618
+ V +P P + + ++ + W I+G+ ++Y++ G D
Sbjct: 416 AAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNV 475
Query: 619 ELQ--VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E Q V T+E + +L T Y+ Y+ A++++G +T VP +
Sbjct: 476 EYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSL 535
Query: 677 ITLNTTTVTV-WLDSWGDGGCG-ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
+ N + + V WL G ++ + IEY + Q + S V+ E ++ L P
Sbjct: 536 SSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQ--IFSTEVRGNETQLMLNSLQP 593
Query: 735 AAHYQLRITAHNNAG 749
Y++RI+A AG
Sbjct: 594 NKVYRVRISAGTAAG 608
Score = 66.5 bits (155), Expect = 5e-10
Identities = 61/237 (25%), Positives = 93/237 (39%), Gaps = 11/237 (4%)
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
V+G G + T + GLQ Y V + NS E +PS P +
Sbjct: 383 VQGGGGSLVITQI-GLQDAGYYQCVAE--NSAGMACAAASLAVVVREGLPSAPT-RVTAT 438
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
LSS +V V+WE P M I G+ + Y E + L
Sbjct: 439 PLSSSAVLVAWERPEMHSEQII--GFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPN 496
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPN 411
T+Y V A++ G + P HT +DVPSA + + + + I V+W LPPS N
Sbjct: 497 TDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSN 556
Query: 412 GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
G +V Y + + G+E+ + + + P ++ +SA T G G
Sbjct: 557 GQVVKYKIEYGL---GKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFG 610
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
A +AG AA + E +PSAP + A S + +LV+W P + ++G++L+
Sbjct: 407 AENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHY 466
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
G + ++ ++ T + P ++F+V A ++LG + V D
Sbjct: 467 QKAR-GMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDD 525
Query: 482 VPARITSFSRNIVTP 496
VP+ S + P
Sbjct: 526 VPSAAPQLSLSSPNP 540
Score = 39.9 bits (89), Expect = 0.049
Identities = 22/95 (23%), Positives = 40/95 (42%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P ++R+ T+++ W P N I+ Y++ Y + G++ SA V
Sbjct: 851 PSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEV 910
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
L+ T Y ++ A +G S+ V T +E
Sbjct: 911 HGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQE 945
Score = 39.1 bits (87), Expect = 0.086
Identities = 20/53 (37%), Positives = 26/53 (49%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
C+ G+PAP TW + V L R V +G L I Q +D+G Y C N
Sbjct: 164 CHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATN 216
>AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein.
Length = 980
Score = 87.8 bits (208), Expect = 2e-16
Identities = 100/430 (23%), Positives = 170/430 (39%), Gaps = 35/430 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQ--PYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
VP + + I+++W P N ++ Y ++Y E + + V G+
Sbjct: 256 VPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTE---VRGN 312
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT-----TEEVPSGPPQDVRVEAK 181
T + +LQP Y +RI A G PSQ + T VP P +++V+AK
Sbjct: 313 ETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFA-PAELKVQAK 371
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV---LIASGPGGASYTVRTVEGAG 238
+ L+V+W+PP I GY + ++E+ + + G G ++ V V
Sbjct: 372 MES-LVVSWQPPPHPT---QISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKK 427
Query: 239 TARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXX--------MEDVPSLPPGAL 290
+ + L+ L Y V + A+N ++ P LPP +
Sbjct: 428 KVK-QYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHV 486
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQI-SGLHTTLS 348
+ SS S+ + W+ P + Y V ++P W N VT SG +
Sbjct: 487 HAESNSSTSIWLRWKKPDFTTVK--IVNYTVRFSP---WGLRNASLVTYYTSSGEDILIG 541
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSA-PADIKAAVSSRNKILVSWLPP 407
GL+ +T Y V + DG + V T D PS P+D++ + + + + + W PP
Sbjct: 542 GLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPP 601
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
+ PNG +V Y + S E + S E + F + A T +G
Sbjct: 602 TEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGP 661
Query: 468 GEATRVVTVL 477
G +R+ V+
Sbjct: 662 GPFSRLQDVI 671
Score = 85.8 bits (203), Expect = 8e-16
Identities = 82/319 (25%), Positives = 137/319 (42%), Gaps = 34/319 (10%)
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+V V G S + + + + + +AEN G + + + V E +PS P + V
Sbjct: 110 RVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTR-VTAT 168
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
SS+ ++V WE P ++ + I+G+ + +Q+ A G Y
Sbjct: 169 PLSSSAVLVAWERP--EMHSEQIIGFSLHYQK---------ARGMDNVEYQF----AVNN 213
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
+ + L+ + Y V AY+ ++DVPS P L ++ +
Sbjct: 214 DTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAP-QLSLSSPNPSD 272
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAV-TKQISGLHT--TLSGLRRYTNY 356
+RV+W P P NG + Y++ Y G ED + + ++ G T L+ L+ Y
Sbjct: 273 IRVAWLPLPPSLSNGQVVKYKIEYG-----LGKEDQIFSTEVRGNETQLMLNSLQPNKVY 327
Query: 357 SVTVCAFTAAGDGVRAAPVY-----CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPN 411
V + A TAAG G + ++ H + VP APA++K + ++VSW PP P
Sbjct: 328 RVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQ-AKMESLVVSWQPPPHPT 386
Query: 412 GVLVGYTLYMSVIEDGREE 430
+ GY LY E G EE
Sbjct: 387 QI-SGYKLYWR--EVGAEE 402
Score = 72.5 bits (170), Expect = 8e-12
Identities = 59/244 (24%), Positives = 104/244 (42%), Gaps = 22/244 (9%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
+P P + S + ++W +P + II + + Y++A + + V T
Sbjct: 158 LPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKA-RGMDNVEYQFAVNNDTT 216
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V++L+P T Y ++A ++LG S S P V T ++VPS PQ + + + + +++ V
Sbjct: 217 ELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQ-LSLSSPNPSDIRV 275
Query: 189 TWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
W P L NG ++ Y + + G G T E G ++ L+
Sbjct: 276 AWLPLPPSLSNGQVVKYKIEY-------------GLGKEDQIFST-EVRGN-ETQLMLNS 320
Query: 249 LQKHAAYAVVVQAYNSRXXXXXX--XXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSW 304
LQ + Y V + A + M + +P P L+ A +S+ VSW
Sbjct: 321 LQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQA-KMESLVVSW 379
Query: 305 EPPP 308
+PPP
Sbjct: 380 QPPP 383
Score = 71.3 bits (167), Expect = 2e-11
Identities = 64/255 (25%), Positives = 105/255 (41%), Gaps = 12/255 (4%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSADSGNYTCSVENIHG--- 560
C G P PA W NG L R V G+L I+ D+G Y C EN G
Sbjct: 86 CRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMAC 145
Query: 561 -RDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHG-DWE 618
+ V +P P + + ++ + W I+G+ ++Y++ G D
Sbjct: 146 AAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNV 205
Query: 619 ELQ--VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E Q V T+E + +L T Y+ Y+ A++++G +T VP +
Sbjct: 206 EYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSL 265
Query: 677 ITLNTTTVTV-WLDSWGDGGCG-ILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTP 734
+ N + + V WL G ++ + IEY + Q + S V+ E ++ L P
Sbjct: 266 SSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQ--IFSTEVRGNETQLMLNSLQP 323
Query: 735 AAHYQLRITAHNNAG 749
Y++RI+A AG
Sbjct: 324 NKVYRVRISAGTAAG 338
Score = 66.5 bits (155), Expect = 5e-10
Identities = 61/237 (25%), Positives = 93/237 (39%), Gaps = 11/237 (4%)
Query: 234 VEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCN 293
V+G G + T + GLQ Y V + NS E +PS P +
Sbjct: 113 VQGGGGSLVITQI-GLQDAGYYQCVAE--NSAGMACAAASLAVVVREGLPSAPT-RVTAT 168
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
LSS +V V+WE P M I G+ + Y E + L
Sbjct: 169 PLSSSAVLVAWERPEMHSEQII--GFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPN 226
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW--LPPSSPN 411
T+Y V A++ G + P HT +DVPSA + + + + I V+W LPPS N
Sbjct: 227 TDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSN 286
Query: 412 GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
G +V Y + + G+E+ + + + P ++ +SA T G G
Sbjct: 287 GQVVKYKIEYGL---GKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFG 340
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
A +AG AA + E +PSAP + A S + +LV+W P + ++G++L+
Sbjct: 137 AENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHY 196
Query: 422 SVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDS 481
G + ++ ++ T + P ++F+V A ++LG + V D
Sbjct: 197 QKAR-GMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDD 255
Query: 482 VPARITSFSRNIVTP 496
VP+ S + P
Sbjct: 256 VPSAAPQLSLSSPNP 270
Score = 39.9 bits (89), Expect = 0.049
Identities = 22/95 (23%), Positives = 40/95 (42%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P ++R+ T+++ W P N I+ Y++ Y + G++ SA V
Sbjct: 581 PSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEV 640
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
L+ T Y ++ A +G S+ V T +E
Sbjct: 641 HGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQE 675
>BX538018-1|CAD97965.1| 2444|Homo sapiens hypothetical protein
protein.
Length = 2444
Score = 87.4 bits (207), Expect = 2e-16
Identities = 154/685 (22%), Positives = 254/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1448 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1502
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1503 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1557
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1558 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1598
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1599 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1653
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ L+ Y V+V A +G+
Sbjct: 1654 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIESLQPTVEYVVSVYAQNPSGESQ 1711
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1712 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1760
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1761 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1818
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1819 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1878
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1879 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 1930
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1931 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1989
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1990 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2043
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 2044 VTEA-TITGLEPGTEYTIYVIALKN 2067
Score = 60.1 bits (139), Expect = 4e-08
Identities = 127/596 (21%), Positives = 217/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 795 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 849
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 850 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 905
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 906 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 949
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 950 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 1007
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 1008 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 1060
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 1061 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1113
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1114 TGYRLTVGLTRRGQ---PRQYNVGPSDSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1170
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1171 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1220
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G + +S YT V + +V P PP +++ D+ L
Sbjct: 1221 TSDSGNIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1280
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1281 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1336
Score = 56.0 bits (129), Expect = 7e-07
Identities = 147/695 (21%), Positives = 245/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V S +
Sbjct: 1087 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSDSKY 1140
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1141 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1196
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G +SGL
Sbjct: 1197 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSG------NIVVSGLT 1233
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1234 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1285
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1286 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1342
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1343 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1397
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1398 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1455
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1456 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1509
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1510 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1566
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1567 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1626
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1627 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1678
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ L P Y + + A N +G + L
Sbjct: 1679 AGPDQTEMTIESLQPTVEYVVSVYAQNPSGESQPL 1713
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 711 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 766
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 767 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 824
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 825 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 881
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 882 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 932
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 933 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 987
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 988 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 1043
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 1044 PISRNTFAEVTGLS-PGVTYYFKVFA 1068
Score = 51.2 bits (117), Expect = 2e-05
Identities = 142/697 (20%), Positives = 259/697 (37%), Gaps = 80/697 (11%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
S VP P++++ ++ + I WT P S + Y V P + P + +
Sbjct: 993 SDTVPS-PRDLQFVEVTDVKVTIMWTPP---ESAVTGYRVDV--IPVNLPGEHGQRLPIS 1046
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
T A V L P +Y+ ++ A + +S+P Q T + P +++ ++ +
Sbjct: 1047 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD-----APTNLQFVNETDST 1101
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W PP+ I GY + TV + Y V G + S+
Sbjct: 1102 VLVRWTPPR-----AQITGYRL---------TVGLTRRGQPRQYNV------GPSDSKYP 1141
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L LQ + Y V + A ++ S+PP + ++ ++ ++W
Sbjct: 1142 LRNLQPASEYTVSLVAIKGN-QESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWT 1197
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P P R G G R + G SG + +SGL Y T+
Sbjct: 1198 PAP---RIGFKLGVRPSQG------GEAPREVTSDSG-NIVVSGLTPGVEYVYTIQVLRD 1247
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL-VSWLPPSSPNGVLVGYTLYMSVI 424
+ R AP+ + S P ++ + +L VSW ++P+ + GY + +
Sbjct: 1248 GQE--RDAPIVNKVVTPL-SPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRI-TTTP 1301
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVP 483
+G++ + + ++ S P ++ VS T + E+ + T++P+ P
Sbjct: 1302 TNGQQGNSLEEVVHADQSSCTFDNLSPGL--EYNVSVYTVKDDKESVPISDTIIPAVPPP 1359
Query: 484 A--RITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
R T+ + + W S+ V + V E + + S +
Sbjct: 1360 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-------RYSPVKNEEDVAELSISPSDNAV 1412
Query: 541 SMTQSADSGNYTCSVENIHGRDEVT-YTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGD 598
+T Y SV +++ + E T K P + D A+S + W
Sbjct: 1413 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP-- 1470
Query: 599 GGSPILGYVINYKREH--GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
+ I GY I + EH G E +V + L NL GT Y + I A N G
Sbjct: 1471 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1525
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
+ + TV P+ +++ T++ + SW + Y+ I Y E +
Sbjct: 1526 SPLLIGQQSTVSDVPRDLEVVAATPTSLLI---SWDAPAVTVRYYRITYGETGGNS-PVQ 1581
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALA 753
+V ++ ++SGL P Y + + A G + A
Sbjct: 1582 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1618
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1993 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 2044
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 2045 TEATITGLEPGTEYTIYVIALKNNQKSEP 2073
>BX538017-1|CAD97964.1| 2444|Homo sapiens hypothetical protein
protein.
Length = 2444
Score = 87.4 bits (207), Expect = 2e-16
Identities = 154/685 (22%), Positives = 254/685 (37%), Gaps = 73/685 (10%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P I D + + + W P A I Y +++ PE + P++ VP S S
Sbjct: 1448 DSPTGIDFSDITANSFTVHWIAPRA---TITGYRIRHH--PEHFSGRPREDRVPHSRNSI 1502
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++ NL P T Y + I+A N G+ E P+ + V S P+D+ V A + T L+++W
Sbjct: 1503 TLTNLTPGTEYVVSIVALN--GREE--SPLLIGQQSTV-SDVPRDLEVVAATPTSLLISW 1557
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+ P + Y + + E NS V + PG ++S T+SGL+
Sbjct: 1558 DAPA-----VTVRYYRITYGETGGNSPVQEFTVPG--------------SKSTATISGLK 1598
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + V A R P +Q + S+ V W P
Sbjct: 1599 PGVDYTITVYAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLP---- 1653
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + GYRVT P + G T T+ L+ Y V+V A +G+
Sbjct: 1654 -SSSPVTGYRVTTTP-KNGPGPTKTKTAGPDQTEMTIESLQPTVEYVVSVYAQNPSGESQ 1711
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE 430
T D P A V S I ++W SP G + Y + S ED
Sbjct: 1712 PLVQT-AVTNIDRPKGLAFTDVDVDS---IKIAW---ESPQGQVSRYRVTYSSPED---- 1760
Query: 431 GTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFS 490
G H+ +P R ++ VS + E+ ++ S ++PA T
Sbjct: 1761 GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT-QSTAIPAP-TDLK 1818
Query: 491 RNIVTP------W-KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT 543
VTP W N+ L+ +V V T M + L V S +
Sbjct: 1819 FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1878
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPI 603
S + T + G V T+E PP+ V D+ ++ + W + + I
Sbjct: 1879 VSVYALKDTLTSRPAQG---VVTTLENVSPPRR--ARVTDATETTITISWRTKTE---TI 1930
Query: 604 LGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY 662
G+ ++ +G + ++ + + L GT Y++Y+ N P ++ A
Sbjct: 1931 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDAS 1989
Query: 663 TKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
T P S + L TT ++ L SW I ++I+Y + P +V
Sbjct: 1990 TAIDAP-----SNLRFLATTPNSL-LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2043
Query: 723 TERVFSVSGLTPAAHYQLRITAHNN 747
+++GL P Y + + A N
Sbjct: 2044 VTEA-TITGLEPGTEYTIYVIALKN 2067
Score = 60.1 bits (139), Expect = 4e-08
Identities = 127/596 (21%), Positives = 217/596 (36%), Gaps = 61/596 (10%)
Query: 56 VTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VT + G + P + + V + + + +SW + + + + V+Y+ + E
Sbjct: 795 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV---SASDTVSGFRVEYELSEEG-- 849
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
PQ + +P + TS ++ +L P Y + + + G+ Q + ++T++ P D
Sbjct: 850 DEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD 905
Query: 176 VRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVE 235
V+ T ++V W PQ I GY ++ + G+S + E
Sbjct: 906 PTVDQVDDTSIVVRWSRPQ-----APITGY-----------RIVYSPSVEGSSTELNLPE 949
Query: 236 GAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNAL 295
A + G+Q + V + S + VPS P LQ +
Sbjct: 950 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS--PRDLQFVEV 1007
Query: 296 SSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS-GLHTTLSGLRRYT 354
+ V + W PP + GYRV PV E IS ++GL
Sbjct: 1008 TDVKVTIMWTPP-----ESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEVTGLSPGV 1060
Query: 355 NYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y V A G + P+ + AP +++ + + +LV W PP + +
Sbjct: 1061 TYYFKV---FAVSHGRESKPLTAQQTTKL-DAPTNLQFVNETDSTVLVRWTPPRAQ---I 1113
Query: 415 VGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG-EATRV 473
GY L + + G+ + + PS + P + + + A E +AT V
Sbjct: 1114 TGYRLTVGLTRRGQ---PRQYNVGPSDSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1170
Query: 474 VTVL-PSDSVPARITSFSR-NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
T L P S+P T + IV W + K+GV P+ G E+ R+
Sbjct: 1171 FTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGV-RPSQ-------GGEAP-REV 1220
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHL 591
S G + +S YT V + +V P PP +++ D+ L
Sbjct: 1221 TSDSGNIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1280
Query: 592 QWSDQGDGGSPILGYVIN---YKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYI 644
S + I GY I + G+ E V A S NL G Y + +
Sbjct: 1281 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1336
Score = 56.0 bits (129), Expect = 7e-07
Identities = 147/695 (21%), Positives = 245/695 (35%), Gaps = 79/695 (11%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P N++ +++ T+ + WT P A I Y + P++ V S +
Sbjct: 1087 DAPTNLQFVNETDSTVLVRWTPPRA---QITGYRLTVGLTRRG---QPRQYNVGPSDSKY 1140
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
++NLQPA+ Y + ++A + Q P TT + S PP + V + T +++TW
Sbjct: 1141 PLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVITW 1196
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P R +G+ +G + S G A V + G +SGL
Sbjct: 1197 TPAPR-------IGFKLGVR----------PSQGGEAPREVTSDSG------NIVVSGLT 1233
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV-RVSWEPPPM 309
Y +Q P PP L A V VSWE
Sbjct: 1234 PGVEYVYTIQVLRDGQERDAPIVNKVV----TPLSPPTNLHLEANPDTGVLTVSWE---- 1285
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + GYR+T P GN T L Y+V+V +T D
Sbjct: 1286 RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVK-DD 1342
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ P+ VP P D++ + + V+W PP P+ L + + S +++ E
Sbjct: 1343 KESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKN--E 1397
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E + +SPS + + P + VS+ E R DS P I F
Sbjct: 1398 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGI-DF 1455
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTM--NGVGLESTLRKNVSSDGTLTISMTQSAD 547
S S + + + A T + + + R++ +I++T
Sbjct: 1456 SDITAN------SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1509
Query: 548 SGNYTCSVENIHGRDEVTYTV--EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILG 605
Y S+ ++GR+E + + V P L VV + SL + W +
Sbjct: 1510 GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---AVTVRY 1566
Query: 606 YVINYKREHGD--WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y I Y G+ +E V S + L G Y + + A G +
Sbjct: 1567 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1626
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQ---WRLVSNS 719
T KP Q+ + +++V WL S V YR + P+ + +
Sbjct: 1627 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSP--------VTGYRVTTTPKNGPGPTKTKT 1678
Query: 720 VQATERVFSVSGLTPAAHYQLRITAHNNAGHALAL 754
+ ++ L P Y + + A N +G + L
Sbjct: 1679 AGPDQTEMTIESLQPTVEYVVSVYAQNPSGESQPL 1713
Score = 51.6 bits (118), Expect = 2e-05
Identities = 79/386 (20%), Positives = 144/386 (37%), Gaps = 34/386 (8%)
Query: 82 QSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSY 141
Q + I W P S I YI++++ P++ ++ +PG + S +++ L+P Y
Sbjct: 711 QPNSHPIQWNAPQP--SHISKYILRWR--PKNSVGRWKEATIPGHLNSYTIKGLKPGVVY 766
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGN 201
++I+ + G E ++ TT+ P V E + L+ T E ++ +
Sbjct: 767 EGQLISIQQYGHQEVTRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVT-EITASS 824
Query: 202 ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQA 261
+ +V + S V G + T+ + L Y V V
Sbjct: 825 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ 881
Query: 262 YNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV 321
+ D P P + + S+ V W P + GYR+
Sbjct: 882 ISEDGEQSLILSTSQTTAPDAPPDPT----VDQVDDTSIVVRWSRP-----QAPITGYRI 932
Query: 322 TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE- 380
Y+P + G+ + + TLS L+ Y++T+ A + + PV E
Sbjct: 933 VYSPSVE--GSSTELNLPETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQET 987
Query: 381 -----EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKR 435
D +P D++ + K+ + W PP S + GY + + + E G +
Sbjct: 988 TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES---AVTGYRVDVIPVNLPGEHG-QRL 1043
Query: 436 MLSPSTLSHETSRSPPRATHQFWVSA 461
+S +T + T S P T+ F V A
Sbjct: 1044 PISRNTFAEVTGLS-PGVTYYFKVFA 1068
Score = 51.2 bits (117), Expect = 2e-05
Identities = 142/697 (20%), Positives = 259/697 (37%), Gaps = 80/697 (11%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
S VP P++++ ++ + I WT P S + Y V P + P + +
Sbjct: 993 SDTVPS-PRDLQFVEVTDVKVTIMWTPP---ESAVTGYRVDV--IPVNLPGEHGQRLPIS 1046
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
T A V L P +Y+ ++ A + +S+P Q T + P +++ ++ +
Sbjct: 1047 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD-----APTNLQFVNETDST 1101
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
++V W PP+ I GY + TV + Y V G + S+
Sbjct: 1102 VLVRWTPPR-----AQITGYRL---------TVGLTRRGQPRQYNV------GPSDSKYP 1141
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L LQ + Y V + A ++ S+PP + ++ ++ ++W
Sbjct: 1142 LRNLQPASEYTVSLVAIKGN-QESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWT 1197
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTA 365
P P R G G R + G SG + +SGL Y T+
Sbjct: 1198 PAP---RIGFKLGVRPSQG------GEAPREVTSDSG-NIVVSGLTPGVEYVYTIQVLRD 1247
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL-VSWLPPSSPNGVLVGYTLYMSVI 424
+ R AP+ + S P ++ + +L VSW ++P+ + GY + +
Sbjct: 1248 GQE--RDAPIVNKVVTPL-SPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRI-TTTP 1301
Query: 425 EDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVP 483
+G++ + + ++ S P ++ VS T + E+ + T++P+ P
Sbjct: 1302 TNGQQGNSLEEVVHADQSSCTFDNLSPGL--EYNVSVYTVKDDKESVPISDTIIPAVPPP 1359
Query: 484 A--RITSFSRNIV-TPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
R T+ + + W S+ V + V E + + S +
Sbjct: 1360 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-------RYSPVKNEEDVAELSISPSDNAV 1412
Query: 541 SMTQSADSGNYTCSVENIHGRDEVT-YTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGD 598
+T Y SV +++ + E T K P + D A+S + W
Sbjct: 1413 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP-- 1470
Query: 599 GGSPILGYVINYKREH--GDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC 656
+ I GY I + EH G E +V + L NL GT Y + I A N G
Sbjct: 1471 -RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1525
Query: 657 DIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
+ + TV P+ +++ T++ + SW + Y+ I Y E +
Sbjct: 1526 SPLLIGQQSTVSDVPRDLEVVAATPTSLLI---SWDAPAVTVRYYRITYGETGGNS-PVQ 1581
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALA 753
+V ++ ++SGL P Y + + A G + A
Sbjct: 1582 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1618
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 1993 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 2044
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 2045 TEATITGLEPGTEYTIYVIALKNNQKSEP 2073
>X64699-1|CAA45940.1| 531|Homo sapiens titin protein.
Length = 531
Score = 86.6 bits (205), Expect = 4e-16
Identities = 94/385 (24%), Positives = 158/385 (41%), Gaps = 27/385 (7%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLV-GYTLYMSVIEDGREEGTHKRMLSPSTL 442
P P + K +R+ + +SW P G + GY + + G E T M +P T
Sbjct: 12 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVG--EWT---MCTPPTG 66
Query: 443 SHETS----RSPPRATHQFWVSASTRLGEGEATRVV-TVLPSDSVPARITSFS---RNIV 494
++T+ + + + F + A + G GE V ++ + + A R I+
Sbjct: 67 INKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 126
Query: 495 TPWKE-NISLSCNKVGVPAPATTW-TMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYT 552
++ L G P P W ++G ++ + SS +L + DSG YT
Sbjct: 127 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYT 186
Query: 553 CSVENIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQ-GDGGSPILGYVINY 610
++EN G TV V P PP+ L V + DS+ + W DGGS I Y++
Sbjct: 187 LTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVE- 245
Query: 611 KRE--HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
KRE + + + + L G Y +TA N G GLP VP
Sbjct: 246 KREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP 305
Query: 669 VKPKHSQM--ITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERV 726
P + +T N+ +++ W DGG I+ +++E + +W + V++ + V
Sbjct: 306 QPPGKITVDDVTRNSVSLS-WTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR-VKSLQAV 363
Query: 727 FSVSGLTPAAHYQLRITAHNNAGHA 751
++ LT Y R+ A N G +
Sbjct: 364 --ITNLTQGEEYLFRVVAVNEKGRS 386
Score = 86.2 bits (204), Expect = 6e-16
Identities = 123/537 (22%), Positives = 203/537 (37%), Gaps = 41/537 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPES-WPS-TPQKVIVPGS 126
P P N +VID ++ +SW++P Y G I YIV+ + W TP I +
Sbjct: 12 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI---N 68
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T+ V+ L Y+ RI A N+ G E + EE P D+ +E + +
Sbjct: 69 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINI 128
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTL 246
G L +V + T + G + ++ + L
Sbjct: 129 RA-----------GGSLRLFV---PIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVL 174
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP 306
+ ++ + + NS + D PS PP L+ ++ SV ++WEP
Sbjct: 175 DNVNRYDSGKYTLTLENS---SGTKSAFVTVRVLDTPS-PPVNLKVTEITKDSVSITWEP 230
Query: 307 PPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P + G + I + Y V T + AV + L+ +Y V A
Sbjct: 231 PLLDGGSKI-KNYIVEKREATR--KSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 287
Query: 367 GDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIE 425
G G+ A +VP P I +RN + +SW P G ++ Y + M
Sbjct: 288 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 347
Query: 426 DGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV-VTVLPSDSV-- 482
+ + + +++ T + F V A G + + V ++ D V
Sbjct: 348 SEKWSECARVKSLQAVITNLTQGEE----YLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE 403
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTLT 539
P +FS V ++ + + G P P TWT +G+ L+ T R NV+ TL+
Sbjct: 404 PDVKPAFSSYSVQVGQD-LKMEVPIFGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLS 462
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVV--DSYADSLHLQWS 594
I T D G Y +V N+ G+ + + P PP V D A+S+ L W+
Sbjct: 463 IKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWN 519
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYK-EAPESWPSTPQKVIVPG 125
+VP+ P I V D ++ +SWT+P + G S II YIV+ + + E W + +
Sbjct: 303 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 362
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEP 156
+T NL Y R++A N G+S+P
Sbjct: 363 VIT-----NLTQGEEYLFRVVAVNEKGRSDP 388
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 7/122 (5%)
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVE-VKVP--PQPPILAVVDSYA-DSLHLQWSD 595
I Q S + + EN +G T + +KV PQPP VD +S+ L W+
Sbjct: 268 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 327
Query: 596 -QGDGGSPILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
+ DGGS I+ Y++ + +H + W E + + V+ NL G Y + A N G
Sbjct: 328 PEHDGGSKIIQYIVEMQAKHSEKWSEC-ARVKSLQAVITNLTQGEEYLFRVVAVNEKGRS 386
Query: 654 LP 655
P
Sbjct: 387 DP 388
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 83.8 bits (198), Expect = 3e-15
Identities = 39/108 (36%), Positives = 64/108 (59%)
Query: 59 DLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTP 118
D I L+ Q P P I + D ++RTI + WT + GNSPI Y ++ K +SW S
Sbjct: 704 DRGIIQLTVQEPPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQ 763
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE 166
+ V + SA++ ++ P+++Y +R+ A+NR+G+SEPS + +T E
Sbjct: 764 RTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADE 811
Score = 70.5 bits (165), Expect = 3e-11
Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 12/186 (6%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD------ 535
+PA ITS+ + + +SC G W + + + + S
Sbjct: 616 IPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEE 675
Query: 536 --GTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQW 593
TL I T DSG ++C N +G D + V+ PP PP + + D A ++ L+W
Sbjct: 676 VISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIEIKDVKARTITLRW 735
Query: 594 SDQGDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNR 649
+ DG SPI GY I K + W+ Q V + + ++ + Y + + A NR
Sbjct: 736 TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNR 795
Query: 650 IGTGLP 655
IG P
Sbjct: 796 IGKSEP 801
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG----VGLESTLR 529
V V+ D P I++FS +V+P E +SL CN G P P TWT++ G +
Sbjct: 228 VQVVLEDGTPKIISAFSEKVVSP-AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRIS 286
Query: 530 KNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+ ++S+G L IS +Q D G Y C+ N G V Y + V
Sbjct: 287 QMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAG--VVLYQARINV 331
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLES 526
+ + R+ P++S P+ + F + + L C +G P P W + + LE
Sbjct: 39 QSNSARLFVSDPANSAPSILDGFDHRKAMAG-QRVELPCKALGHPEPDYRWLKDNMPLEL 97
Query: 527 TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ R + G L I + +DSG+Y C V N +G +V + VK P
Sbjct: 98 SGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 143
Score = 37.9 bits (84), Expect = 0.20
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMN-GVGLESTL------RKNVSSDGTLTISMTQSADSGNYTC 553
+ L+C+ G P P W + G G+ R V S+G+L I DSG Y C
Sbjct: 537 VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLC 596
Query: 554 SVENIHGRD-EVTYTVEVKVP 573
V N G D + + VK+P
Sbjct: 597 KVSNDVGADVSKSMYLTVKIP 617
Score = 33.5 bits (73), Expect = 4.3
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 467 EGEATRVVTVLP--SDSVPARITSFSRNIVTPWK-------ENISLSCNKVGVPAPAT-T 516
EGE T V V P S S +T + P++ + + + C V P T T
Sbjct: 400 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITIT 459
Query: 517 WTMNGVGLESTLR---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
W +G + +L N+ +L IS +GNYTC N E + V+VP
Sbjct: 460 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 519
Query: 574 PQ 575
P+
Sbjct: 520 PK 521
>Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C
gene protein.
Length = 1274
Score = 83.4 bits (197), Expect = 4e-15
Identities = 63/231 (27%), Positives = 100/231 (43%), Gaps = 7/231 (3%)
Query: 525 ESTLRKNVSSDGTL-TISMTQSADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPILAVV 582
E +R + D ++ T+ + D G YT +V+N G D+V TV+V VP P +
Sbjct: 722 EGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKIS 781
Query: 583 DSYADSLHLQWSDQG-DGGSPILGYVINYKREHG-DWEELQVE-AGTSEHVLPNLWCGTR 639
+ DS +QW DGG PILGY++ K++ W +L + H + G
Sbjct: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQELSHEARRMIEGVV 841
Query: 640 YQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
Y++ + A N IG P + P +P H + ++ TTV++ W G G+
Sbjct: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +EY +W + + V L A R+ AHN AG
Sbjct: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSIL-VKDLPTGARLLFRVRAHNMAG 951
Score = 65.3 bits (152), Expect = 1e-09
Identities = 94/385 (24%), Positives = 140/385 (36%), Gaps = 22/385 (5%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
DVP P A + + + S V WEPP G IL GY + W N D +
Sbjct: 770 DVPDAP-AAPKISNVGEDSCTVQWEPPAYDGGQPIL-GYILERKKKKSYRWMQLNFDLIQ 827
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y + V A A G + PS P + S
Sbjct: 828 ELSHEARRMIEGVV----YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+ + W PP G L GY++ +G E S P A
Sbjct: 884 TTVSLKWRPPERVGAGGLDGYSV--EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
Query: 457 FWVSASTRLGEGE---ATRVVTVLPSDSVPA-RITSFSRNIVTPWK-ENISLSCNKVGVP 511
F V A G G T VTV P ++ R + E ++L G P
Sbjct: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
Query: 512 APATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P TWT G L E +N +D L I + SG Y +V + D+ T ++
Sbjct: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQGD-GGSPILGYVI-NYKREHGDWEELQVEAGT 626
V P PP L V D++ ++ L+W D G + + GY + ++ +W +
Sbjct: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRR 1121
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG 651
+ V+P L G Y + + N +G
Sbjct: 1122 THCVVPELIIGNGYYFRVFSQNMVG 1146
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 27/196 (13%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ P ++ + + + W P Y G PI+ YI++ K+ W +I
Sbjct: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLI---Q 827
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD---VRVEAKSS 183
S + + Y +R+ A N +G S PS Q +P GPP + + VE S
Sbjct: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSD 883
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGF------------QELNSNSTVLIASGPGGAS--Y 229
T + + W PP+R + G + GY V + Q L ++++L+ P GA +
Sbjct: 884 TTVSLKWRPPER-VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
Query: 230 TVRTVEGAGTARSRTT 245
VR AG TT
Sbjct: 943 RVRAHNMAGPGAPVTT 958
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C G P P +W NG+ L R + S G LT+ + + D G Y C N+
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1259
Query: 560 GRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1260 GEARCECRLEVRVP 1273
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
PPQD+RV + + W+PPQ D+ N + GY V
Sbjct: 1068 PPQDLRVTDAWGLNVALEWKPPQ-DVGNTELWGYTV 1102
>X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding
protein C protein.
Length = 1274
Score = 83.4 bits (197), Expect = 4e-15
Identities = 63/231 (27%), Positives = 100/231 (43%), Gaps = 7/231 (3%)
Query: 525 ESTLRKNVSSDGTL-TISMTQSADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPILAVV 582
E +R + D ++ T+ + D G YT +V+N G D+V TV+V VP P +
Sbjct: 722 EGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKIS 781
Query: 583 DSYADSLHLQWSDQG-DGGSPILGYVINYKREHG-DWEELQVE-AGTSEHVLPNLWCGTR 639
+ DS +QW DGG PILGY++ K++ W +L + H + G
Sbjct: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQELSHEARRMIEGVV 841
Query: 640 YQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
Y++ + A N IG P + P +P H + ++ TTV++ W G G+
Sbjct: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +EY +W + + V L A R+ AHN AG
Sbjct: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSIL-VKDLPTGARLLFRVRAHNMAG 951
Score = 65.3 bits (152), Expect = 1e-09
Identities = 94/385 (24%), Positives = 140/385 (36%), Gaps = 22/385 (5%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
DVP P A + + + S V WEPP G IL GY + W N D +
Sbjct: 770 DVPDAP-AAPKISNVGEDSCTVQWEPPAYDGGQPIL-GYILERKKKKSYRWMQLNFDLIQ 827
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y + V A A G + PS P + S
Sbjct: 828 ELSHEARRMIEGVV----YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+ + W PP G L GY++ +G E S P A
Sbjct: 884 TTVSLKWRPPERVGAGGLDGYSV--EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
Query: 457 FWVSASTRLGEGE---ATRVVTVLPSDSVPA-RITSFSRNIVTPWK-ENISLSCNKVGVP 511
F V A G G T VTV P ++ R + E ++L G P
Sbjct: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
Query: 512 APATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P TWT G L E +N +D L I + SG Y +V + D+ T ++
Sbjct: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQGD-GGSPILGYVI-NYKREHGDWEELQVEAGT 626
V P PP L V D++ ++ L+W D G + + GY + ++ +W +
Sbjct: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRR 1121
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG 651
+ V+P L G Y + + N +G
Sbjct: 1122 THCVVPELIIGNGYYFRVFSQNMVG 1146
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 27/196 (13%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ P ++ + + + W P Y G PI+ YI++ K+ W +I
Sbjct: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLI---Q 827
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD---VRVEAKSS 183
S + + Y +R+ A N +G S PS Q +P GPP + + VE S
Sbjct: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSD 883
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGF------------QELNSNSTVLIASGPGGAS--Y 229
T + + W PP+R + G + GY V + Q L ++++L+ P GA +
Sbjct: 884 TTVSLKWRPPER-VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
Query: 230 TVRTVEGAGTARSRTT 245
VR AG TT
Sbjct: 943 RVRAHNMAGPGAPVTT 958
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C G P P +W NG+ L R + S G LT+ + + D G Y C N+
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1259
Query: 560 GRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1260 GEARCECRLEVRVP 1273
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
PPQD+RV + + W+PPQ D+ N + GY V
Sbjct: 1068 PPQDLRVTDAWGLNVALEWKPPQ-DVGNTELWGYTV 1102
>AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isoform B
protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 5202
Score = 83.4 bits (197), Expect = 4e-15
Identities = 82/352 (23%), Positives = 146/352 (41%), Gaps = 34/352 (9%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
++D +SR + ++W P N I +Y + + PG+VT+ +V +L P
Sbjct: 2541 LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGR--------LYLRTPGNVTNCTVMHLHP 2592
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDL 197
T+Y ++ A G S + V T P G P + + + T +I++W+PP
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPPTHP- 2650
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAV 257
NG + + + + + + P S+++R ++ + LS K+ Y V
Sbjct: 2651 -NGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFID------KTSALSPWTKY-EYRV 2700
Query: 258 VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQ 317
++ + PP L +V+V+W+PP + +NG +
Sbjct: 2701 LMSTLHGGTNSSAWVEVTTRPSRPAGVQPP---VVTVLEPDAVQVTWKPPLI--QNGDIL 2755
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA----GDGVRAA 373
Y + + P D + VT + L ++ L +TNYSVT+ A + G +
Sbjct: 2756 SYEI-HMP--DPHITLTNVTSAV--LSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESL 2810
Query: 374 PVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
P Y T VP + S + +++SW PPS PNG + Y L I+
Sbjct: 2811 PTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQ 2862
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 67.7 bits (158), Expect = 2e-10
Identities = 65/231 (28%), Positives = 104/231 (45%), Gaps = 23/231 (9%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRG--RNGILQGYRV--TYAPVTDWYGNEDAVTK 338
P P + +L+ S+ V+W+ P +RG IL+ Y T P E T
Sbjct: 1954 PQSVPTPSRVRSLNGYSIEVTWDEPVVRGVIEKYILKAYSEDSTRPPRMPSASAEFVNTS 2013
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
++G+ L+GL + NY+VT+ A T AG + + T ++ P A S +
Sbjct: 2014 NLTGI---LTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQE-VQPPVAKSLPS 2069
Query: 399 KILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFW 458
+L+SW PP NG++ Y LYM DGR + S S ++ + HQF
Sbjct: 2070 SLLLSWNPPKKANGIITQYCLYM----DGR------LIYSGSEENYIVTDLAVFTPHQFL 2119
Query: 459 VSASTRLGEGEATRVV---TVLPSDSVPARITSF--SRNIVTPWKENISLS 504
+SA T +G ++ V+ LP + V + + + SR I WK+ +S
Sbjct: 2120 LSACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKIS 2170
Score = 67.7 bits (158), Expect = 2e-10
Identities = 78/346 (22%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+Q++W P N I++Y + + + + V +V S V +L P T+Y + I
Sbjct: 2740 VQVTWKPPLIQNGDILSYEIHMPDPHITLTN------VTSAVLSQKVTHLIPFTNYSVTI 2793
Query: 146 IA----ENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+A LG S P VTT VP GP + V S + ++++W+PP + N
Sbjct: 2794 VACSGGNGYLGGCTESLPTYVTTHPTVPQNVGP---LSVIPLSESYVVISWQPPSKP--N 2848
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
G L Y + +++ +AS P + +GT GL + Y ++
Sbjct: 2849 GPNLRYELLRRKIQQP----LASNPPEDLNRWHNIY-SGTQWLYED-KGLSRFTTYEYML 2902
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPP-GA-LQCNALSSQSVRVSWEPPPMRGRNGILQ 317
+NS + + LP GA L + L+ ++ V W P ++ G ++
Sbjct: 2903 FVHNS----VGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query: 318 GYRVTYAPVTDWYGNEDAVTKQISGLHTTLSG-LRRYTNYSVTVCAFTAAGDGVRAAPVY 376
Y + ++ T + D++ K + +++ + G L+ T Y + + F + +A ++
Sbjct: 2959 YYTLFWSSAT----SNDSL-KILPDVNSHVIGHLKPNTEYWIFISVFNGV-HSINSAGLH 3012
Query: 377 CHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMS 422
T + P + + + + V W PS+PNGV+ Y++Y++
Sbjct: 3013 ATTCDGEPQGMLPPEVVIINSTAVRVIWTSPSNPNGVVTEYSIYVN 3058
Score = 64.9 bits (151), Expect = 2e-09
Identities = 79/317 (24%), Positives = 133/317 (41%), Gaps = 41/317 (12%)
Query: 108 KEAPESWPSTPQKVIVPGSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTT 165
K + E S+ ++ I GSV + S NL+P +Y RI A N G+ S+ V+ T
Sbjct: 3437 KASIEEMCSSAEETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGL-SKAVRARTK 3495
Query: 166 EEVPSG--PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
E+VP G PP +++ T +++ W P + NG I+ YY+ L+ +G
Sbjct: 3496 EDVPQGVSPPTWTKIDNLEDT-IVLNWRKPIQS--NGPII-YYI-----------LLRNG 3540
Query: 224 PGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
GT+ S + G+Q Y+ ++A
Sbjct: 3541 ---------IERFRGTSLSFSDKEGIQPFQEYSYQLKACTVAGCATSSKVVAATTQGVPE 3591
Query: 284 SLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL 343
S+ P ++ ALS+ ++ +SW P NG+++ Y++ G T
Sbjct: 3592 SILPPSI--TALSAVALHLSWSVPEKS--NGVIKEYQIRQV------GKGLIHTDTTDRR 3641
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILV 402
T++GL+ YTNYS T+ A T+AG + P T + P + + + + +
Sbjct: 3642 QHTVTGLQPYTNYSFTLTACTSAG-CTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVEL 3700
Query: 403 SWLPPSSPNGVLVGYTL 419
W P PNG++ Y L
Sbjct: 3701 YWSLPEKPNGLVSQYQL 3717
Score = 64.1 bits (149), Expect = 3e-09
Identities = 98/399 (24%), Positives = 154/399 (38%), Gaps = 55/399 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P I + + + ISW P N I +Y +Q E + P V + T
Sbjct: 4268 PPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRNEMLYPFSFDP----VTFNYTD--- 4320
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTW 190
+ L P ++Y + A G S S+P +TT E PS PP + A S+T++ V W
Sbjct: 4321 EELLPFSTYSYALQACTSGGCST-SKPTSITTLEAAPSEVSPPD---LWAVSATQMNVCW 4376
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP + NG I Y V + S + G G +S LQ
Sbjct: 4377 SPPT--VQNGKITKYLVRYDNKES-------------------LAGQGLC---LLVSHLQ 4412
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP-SLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A + ME +P ++ LQ S+S+ ++W+PP
Sbjct: 4413 PYSQYNFSLVACTN-GGCTASVSKSAWTMEALPENMDSPTLQVTG--SESIEITWKPP-- 4467
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R NG ++ Y + + G E T G+ YS TV A + G G
Sbjct: 4468 RNPNGQIRSYELRRDGTIVYTGLETRYRD-----FTLTPGVE----YSYTVTASNSQG-G 4517
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ + V T PS K +ILV+W PP NG ++ YTL++ + +
Sbjct: 4518 ILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERET 4577
Query: 430 EGTHKRMLSPS--TLSHETSRSPPRATHQFWVSASTRLG 466
+ H S S+ ++ P ++ + A T LG
Sbjct: 4578 KIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLG 4616
Score = 61.7 bits (143), Expect = 1e-08
Identities = 79/344 (22%), Positives = 134/344 (38%), Gaps = 39/344 (11%)
Query: 85 TIQISWTQPYAGNSP-IINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
++Q+ W+ P N+P Y +Q + +S + P + S V +LQP T Y
Sbjct: 2450 SLQVVWSTPARNNAPGSPRYQLQMRSG-DSTHGFLELFSNPSASLSYEVSDLQPYTEYMF 2508
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNIL 203
R++A N G + S + T E+ P + ++ KS ++VTW+ P++ NG I
Sbjct: 2509 RLVASNGFGSAHSSW-IPFMTAEDKPGPVVPPILLDVKSRM-MLVTWQHPRKS--NGVIT 2564
Query: 204 GYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYN 263
Y + L+ L PG + T+ L + AY V+A
Sbjct: 2565 HYNI---YLHGR---LYLRTPGNV--------------TNCTVMHLHPYTAYKFQVEACT 2604
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
S+ + P P + + + SV +SW+PP NG+++ + +
Sbjct: 2605 SKGCSLSPESQTVWTLPGAPEGIPSP-ELFSDTPTSVIISWQPP--THPNGLVENFTIER 2661
Query: 324 APVTDWYGNEDAVT-KQISGLHT-----TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYC 377
G E+ T + H+ S L +T Y V T G +A V
Sbjct: 2662 RV----KGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVEV 2717
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYM 421
T P+ V + + V+W PP NG ++ Y ++M
Sbjct: 2718 TTRPSRPAGVQPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHM 2761
Score = 61.7 bits (143), Expect = 1e-08
Identities = 86/347 (24%), Positives = 139/347 (40%), Gaps = 34/347 (9%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV-QNLQPATSY 141
S I+I W P N IINY + Y+ + V G++ L+P T Y
Sbjct: 3880 SACIEIKWMPPEKPNGIIINYFI-YRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLY 3938
Query: 142 HLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR---VEAKSSTELIVTWEPPQRDLW 198
R+ A N G E +T T E PPQD +A S+ +++ W P+
Sbjct: 3939 EYRVRACNSKGSVESLW--SLTQTLE---APPQDFPAPWAQATSAHSVLLNWTKPESP-- 3991
Query: 199 NGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVV 258
NG I Y V +QE + T + P ++TV+ GT+ + L GL+ Y +
Sbjct: 3992 NGIISHYRVVYQERPDDPTF---NSPTVHAFTVK-----GTSH-QAHLYGLEPFTTYRIG 4042
Query: 259 VQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
V A N +E PS + + +++ + W PMR NG+++
Sbjct: 4043 VVAAN-HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWS-EPMR-TNGVIKT 4099
Query: 319 YRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCH 378
Y + +D + + +Q L +T Y++T+ A T AG +AP
Sbjct: 4100 YNI----FSDGFLEYSGLNRQF-----LFRRLDPFTLYTLTLEACTRAG-CAHSAPQPLW 4149
Query: 379 TEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIE 425
T+E P + + +SW P +PNG ++ Y + E
Sbjct: 4150 TDEAPPDSQLAPTVHSVKSTSVELSWSEPVNPNGKIIRYEVIRRCFE 4196
Score = 57.6 bits (133), Expect = 2e-07
Identities = 82/350 (23%), Positives = 143/350 (40%), Gaps = 49/350 (14%)
Query: 82 QSRTIQISWTQPYAGNSPIINY-IVQYKEAPESWPS----TPQKVIVPGSVTSASV---- 132
+S ++++SW++P N II Y +++ ++W + +K++ T +
Sbjct: 4167 KSTSVELSWSEPVNPNGKIIRYEVIRRCFEGKAWGNQTIQADEKIVFTEYNTERNTFMYN 4226
Query: 133 -QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG-PPQDVRVEAKSSTELIVTW 190
LQP T +I N G + S V V T + P G P + + + +L+++W
Sbjct: 4227 DTGLQPWTQCEYKIYTWNSAGHTCSSWNV-VRTLQAPPEGLSPPVISYVSMNPQKLLISW 4285
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP++ NG I Y + E+ + P +YT L
Sbjct: 4286 IPPEQS--NGIIQSYRLQRNEM----LYPFSFDPVTFNYTDEE---------------LL 4324
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS-LPPGALQCNALSSQSVRVSWEPPPM 309
+ Y+ +QA S +E PS + P L A+S+ + V W PP +
Sbjct: 4325 PFSTYSYALQACTS-GGCSTSKPTSITTLEAAPSEVSPPDLW--AVSATQMNVCWSPPTV 4381
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+NG + Y V Y N++++ Q GL +S L+ Y+ Y+ ++ A T G
Sbjct: 4382 --QNGKITKYLVR-------YDNKESLAGQ--GLCLLVSHLQPYSQYNFSLVACTNGG-C 4429
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T E +P V+ I ++W PP +PNG + Y L
Sbjct: 4430 TASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYEL 4479
Score = 57.6 bits (133), Expect = 2e-07
Identities = 85/347 (24%), Positives = 139/347 (40%), Gaps = 44/347 (12%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV-PGSVTSASVQNLQPATSYHL 143
T+ + WT P N ++ Y + Y+ + P V++ GS TS L P T Y
Sbjct: 4652 TVSLLWTGPLQPNGKVLYYEL-YRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEY 4710
Query: 144 RIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV---EAKSSTELIVTWEPPQRDLWNG 200
++ A N G++ P T P+ PP+ +R SST+ +V P + NG
Sbjct: 4711 QVWAVNSAGKA----PSSWTWCRTGPA-PPEGLRAPTFHVISSTQAVVNISAPGKP--NG 4763
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
+ Y L +S GA TV G A ++ TL GLQ Y++ V+
Sbjct: 4764 IVSLYR------------LFSSSAHGAE----TVLSEGMA-TQQTLHGLQAFTNYSIGVE 4806
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQSVRVSWEPPPMRGRNGILQG 318
A + P+ P G + Q L+S++ W PP NG++
Sbjct: 4807 ACTC---FNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFP--NGVIHS 4861
Query: 319 YRVTY----APVTDWYGNEDAVTKQISGL--HTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
Y + + P + + + +GL +L GL+ YT Y + V A G +
Sbjct: 4862 YELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVG-STAS 4920
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
+ T++++P A + S+ + + V+W NG L Y L
Sbjct: 4921 EWISFTTQKELPQYRAPF-SVDSNLSVVCVNWSDTFLLNGQLKEYVL 4966
Score = 56.0 bits (129), Expect = 7e-07
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 48/363 (13%)
Query: 70 PEMPKNI---RVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV----- 121
P +P+N+ VI + ISW P N P + Y + ++ + S P +
Sbjct: 2818 PTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWH 2877
Query: 122 -IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
I G+ + L T+Y + N +G + PS+ V VTT +P ++
Sbjct: 2878 NIYSGTQWLYEDKGLSRFTTYEYMLFVHNSVGFT-PSREVTVTTLAGLPERGA-NLTASV 2935
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ T + V W P G + Y + + SN ++ I P S+ +
Sbjct: 2936 LNHTAIDVRWAKPTVQDLQGEVEYYTLFWSSATSNDSLKIL--PDVNSHVI--------- 2984
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNS-RXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
L+ + Y + + +N E LPP + N S +
Sbjct: 2985 ------GHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQGMLPPEVVIIN---STA 3035
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYS-- 357
VRV W P NG++ Y + + N+ T L L +T Y
Sbjct: 3036 VRVIWTSPS--NPNGVVTEYSI-------YVNNKLYKTGMNVPGSFILRDLSPFTIYDIQ 3086
Query: 358 VTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
V VC A V++ T ED PS P ++SR+ + + W+ P PNG+++G
Sbjct: 3087 VEVCTIYAC---VKSNGTQITTVEDTPSDIPTPTIRGITSRS-LQIDWVSPRKPNGIILG 3142
Query: 417 YTL 419
Y L
Sbjct: 3143 YDL 3145
Score = 54.4 bits (125), Expect = 2e-06
Identities = 141/622 (22%), Positives = 222/622 (35%), Gaps = 61/622 (9%)
Query: 159 PVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
P+ T E P +V V+ + S + V WE P R NG +L + V F T
Sbjct: 2318 PLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRP--NG-LLTHSVLF-------TG 2367
Query: 219 LIASGPGGASYTVRTVEGAGTARSRTTL----SGLQKHAAYAVVVQAYNSRXXXXXXXXX 274
+ P G +YT+ V + T L GL Y V V NS+
Sbjct: 2368 IFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPIT 2427
Query: 275 XXXXMEDVPSLPPGAL--QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGN 332
P P G L + ++ + S++V W P G + Y++ +G
Sbjct: 2428 IAM----PPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHGF 2482
Query: 333 EDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIK 391
+ + + L +S L+ YT Y + A G ++ + T ED P I
Sbjct: 2483 LELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFG-SAHSSWIPFMTAEDKPGPVVPPIL 2541
Query: 392 AAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPP 451
V SR +LV+W P NGV+ Y +Y+ GR ++ T+ H P
Sbjct: 2542 LDVKSR-MMLVTWQHPRKSNGVITHYNIYL----HGRLYLRTPGNVTNCTVMH----LHP 2592
Query: 452 RATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS--CNKVG 509
++F V A T G + TV P I S TP IS + G
Sbjct: 2593 YTAYKFQVEACTSKGCSLSPESQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNG 2652
Query: 510 VPAPAT-TWTMNGVGLESTLRKNVSSDGTLTISMTQSAD---SGNYTCSVENIHGRDEVT 565
+ T + G +TL S I T + Y + +HG +
Sbjct: 2653 LVENFTIERRVKGKEEVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS 2712
Query: 566 YTVEVKVPP------QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
VEV P QPP++ V++ D++ + W IL Y I+ H
Sbjct: 2713 AWVEVTTRPSRPAGVQPPVVTVLE--PDAVQVTWKPPLIQNGDILSYEIHMPDPH--ITL 2768
Query: 620 LQVEAGTSEHVLPNLWCGTRYQLYITAFN----RIGTGLPCDIVHAYTKGTVPVKPKHSQ 675
V + + +L T Y + I A + +G + T TVP
Sbjct: 2769 TNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLS 2828
Query: 676 MITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQP-------QWRLVSNSVQATERVF 727
+I L+ + V + W G + Y ++ R++ QP N T+ ++
Sbjct: 2829 VIPLSESYVVISWQPPSKPNGPNLRYELLR-RKIQQPLASNPPEDLNRWHNIYSGTQWLY 2887
Query: 728 SVSGLTPAAHYQLRITAHNNAG 749
GL+ Y+ + HN+ G
Sbjct: 2888 EDKGLSRFTTYEYMLFVHNSVG 2909
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/92 (36%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 83 SRTIQISWTQPYAGNSPIINYIVQYKEA--PES-WPSTPQKVIVP--GSVTSASVQNLQP 137
SRT W+ P N I +Y +Q+ A P+S P TP ++ G AS+ LQP
Sbjct: 4842 SRTASFRWSPPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLGGLQP 4901
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T+Y LR++A N +G S S+ + TT +E+P
Sbjct: 4902 YTTYKLRVVAHNEVG-STASEWISFTTQKELP 4932
Score = 49.6 bits (113), Expect = 6e-05
Identities = 75/291 (25%), Positives = 113/291 (38%), Gaps = 27/291 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+ L P T Y L + A R G + S P Q T+E P V + ST + ++W
Sbjct: 4120 RRLDPFTLYTLTLEACTRAGCAH-SAP-QPLWTDEAPPDSQLAPTVHSVKSTSVELSWSE 4177
Query: 193 PQRDLWNGNILGYYV---GFQ-ELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSG 248
P NG I+ Y V F+ + N T+ +T E T T G
Sbjct: 4178 PVNP--NGKIIRYEVIRRCFEGKAWGNQTI---QADEKIVFTEYNTE-RNTFMYNDT--G 4229
Query: 249 LQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPP 308
LQ + +NS L P + +++ Q + +SW PP
Sbjct: 4230 LQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPEGLSPPVISYVSMNPQKLLISWIPPE 4289
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
NGI+Q YR+ + + + D VT + T L ++ YS + A T+ G
Sbjct: 4290 QS--NGIIQSYRLQRNEMLYPF-SFDPVT-----FNYTDEELLPFSTYSYALQACTSGGC 4341
Query: 369 GVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPPSSPNGVLVGY 417
+ P T E PS +P D+ A S ++ V W PP+ NG + Y
Sbjct: 4342 ST-SKPTSITTLEAAPSEVSPPDLWAV--SATQMNVCWSPPTVQNGKITKY 4389
Score = 49.6 bits (113), Expect = 6e-05
Identities = 96/365 (26%), Positives = 137/365 (37%), Gaps = 36/365 (9%)
Query: 70 PEMPKNIRVIDQQSR---TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS 126
P P + Q+R I ++W P N IINY + +E E S
Sbjct: 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query: 127 --VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP-SGPPQDVRVE-AKS 182
+ S V L+P Y +RI A LG + S + T E P PP + V+ A
Sbjct: 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCAS-SDWTFIQTPEIAPLMQPPPHLEVQMAPG 4647
Query: 183 STELIVT--WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ V+ W P + NG +L YY EL IA+ P S V G+ T+
Sbjct: 4648 GFQPTVSLLWTGPLQP--NGKVL-YY----ELYRRQ---IATQPR-KSNPVLIYNGSSTS 4696
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQ 298
S L Y V A NS P+ P G A + +SS
Sbjct: 4697 FID---SELLPFTEYEYQVWAVNSAGKAPSSWTWCRTG----PAPPEGLRAPTFHVISST 4749
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
V+ P NGI+ YR+ + +G E +++ ++ TL GL+ +TNYS+
Sbjct: 4750 QAVVNISAPGKP--NGIVSLYRLFSSSA---HGAETVLSEGMA-TQQTLHGLQAFTNYSI 4803
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
V A T + T PS + + + W PP PNGV+ Y
Sbjct: 4804 GVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYE 4863
Query: 419 LYMSV 423
L V
Sbjct: 4864 LQFHV 4868
Score = 48.0 bits (109), Expect = 2e-04
Identities = 73/304 (24%), Positives = 114/304 (37%), Gaps = 31/304 (10%)
Query: 121 VIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEA 180
++ G S LQP T Y R+IA + G S S + TT P P RV +
Sbjct: 1907 LVYQGKEQSVYEGGLQPFTEYLYRVIASHE-GGSVYSDWSRGRTTGAAPQSVPTPSRVRS 1965
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
+ + VTW+ P + G I Y + +S + S + E T+
Sbjct: 1966 LNGYSIEVTWDEP---VVRGVIEKYILKAYSEDSTRPPRMPSA---------SAEFVNTS 2013
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPS--LPPGALQCNALSSQ 298
L+GL YAV + A ++ P PP A +L S
Sbjct: 2014 NLTGILTGLLPFKNYAVTLTACTLAGCTESSHALNISTPQEAPQEVQPPVA---KSLPS- 2069
Query: 299 SVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
S+ +SW PP + NGI+ Y + + G+E+ + ++ L +T +
Sbjct: 2070 SLLLSWNPP--KKANGIITQYCLYMDGRLIYSGSEE---------NYIVTDLAVFTPHQF 2118
Query: 359 TVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYT 418
+ A T G ++ V +T + P V I + W P +G+L Y
Sbjct: 2119 LLSACTHVG-CTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYV 2177
Query: 419 LYMS 422
LYMS
Sbjct: 2178 LYMS 2181
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/366 (22%), Positives = 140/366 (38%), Gaps = 51/366 (13%)
Query: 62 IGSLSHQVPE--MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQ 119
+ + + VPE +P +I + + + +SW+ P N I Y ++ T
Sbjct: 3582 VAATTQGVPESILPPSITALSAVA--LHLSWSVPEKSNGVIKEYQIRQVGKGLIHTDTTD 3639
Query: 120 KVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
+ +V LQP T+Y + A G + S+P T + P G R
Sbjct: 3640 R-------RQHTVTGLQPYTNYSFTLTACTSAGCTS-SEPFLGQTLQAAPEGVWVTPRHI 3691
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT 239
+ST + + W P++ NG + Y +L+ N +L G ++T + +E
Sbjct: 3692 IINSTTVELYWSLPEKP--NGLVSQY-----QLSRNGNLLFLGGSEEQNFTDKNLE---- 3740
Query: 240 ARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQS 299
SR T V S E++ PP + S
Sbjct: 3741 PNSRYTYK--------LEVKTGGGSSASDDYIVQTPMSTPEEI--YPP--YNITVIGPYS 3788
Query: 300 VRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQIS--GLH--TTLSGLRRYTN 355
+ V+W PP + ++ V Y + N+ +VT G H T L L +T
Sbjct: 3789 IFVAWIPPGI-----LIPEIPVEYNVLL----NDGSVTPLAFSVGHHQSTLLENLTPFTQ 3839
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSWLPPSSPNGVL 414
Y + + A GV ++ ++ T E P + + A+ S I + W+PP PNG++
Sbjct: 3840 YEIRIQACQNGSCGV-SSRMFVKTPEAAPMDLNSPVLKALGSAC-IEIKWMPPEKPNGII 3897
Query: 415 VGYTLY 420
+ Y +Y
Sbjct: 3898 INYFIY 3903
Score = 44.8 bits (101), Expect = 0.002
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 295 LSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT-TLSGLRRY 353
L S+++ + W+ P R +GIL+ Y + + T + + L +
Sbjct: 2154 LDSRTIHIQWKQP--RKISGILERYVLYMSNHTHDFTIWSVIYNSTELFQDHMLQYVLPG 2211
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
Y + + A T G V A T+ED+P KA S + VSW P PNGV
Sbjct: 2212 NKYLIKLGACTGGGCTVSEASEAL-TDEDIPEGVPAPKAHSYSPDSFNVSWTEPEYPNGV 2270
Query: 414 LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG 466
+ Y LY+ I + + S LS+ P + H F V A T G
Sbjct: 2271 ITSYGLYLDGI----------LIHNSSELSYRAYGFAPWSLHSFRVQACTAKG 2313
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 17/131 (12%)
Query: 79 IDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPA 138
ID TI ++W +P N PII YI+ + E + T S++ + + +QP
Sbjct: 3510 IDNLEDTIVLNWRKPIQSNGPIIYYIL-LRNGIERFRGT--------SLSFSDKEGIQPF 3560
Query: 139 TSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG--PPQDVRVEAKSSTELIVTWEPPQRD 196
Y ++ A G + S+ V TT+ VP PP + A S+ L ++W P++
Sbjct: 3561 QEYSYQLKACTVAGCATSSK-VVAATTQGVPESILPPS---ITALSAVALHLSWSVPEKS 3616
Query: 197 LWNGNILGYYV 207
NG I Y +
Sbjct: 3617 --NGVIKEYQI 3625
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG-LHTTLSG--L 350
AL S + + W PP NGI+ Y + P E + G L G L
Sbjct: 3877 ALGSACIEIKWMPPEKP--NGIIINYFIYRRPAG--IEEESVLFVWSEGALEFMDEGDTL 3932
Query: 351 RRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP 410
R +T Y V A + G V + T E P A +S + +L++W P SP
Sbjct: 3933 RPFTLYEYRVRACNSKGS-VESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKPESP 3991
Query: 411 NGVLVGY-TLYMSVIEDGREEGTHKRMLSPSTLSHETS--RSPPRATHQFWVSASTRLGE 467
NG++ Y +Y +D + SH+ P T++ V A+ GE
Sbjct: 3992 NGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGE 4051
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 16/147 (10%)
Query: 350 LRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWLPP 407
L+ Y Y + A+ + G G+ A V T+EDVP +P + + I+++W P
Sbjct: 3466 LKPYMTYEYRISAWNSYGRGLSKA-VRARTKEDVPQGVSPPTWTKIDNLEDTIVLNWRKP 3524
Query: 408 SSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGE 467
NG ++ Y L + IE R GT S + P + + + A T G
Sbjct: 3525 IQSNGPIIYYILLRNGIE--RFRGT-------SLSFSDKEGIQPFQEYSYQLKACTVAGC 3575
Query: 468 GEATRVVTV----LPSDSVPARITSFS 490
+++VV +P +P IT+ S
Sbjct: 3576 ATSSKVVAATTQGVPESILPPSITALS 3602
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS--APADIKAAVSSRNKILVSWL 405
+GL+ +T + + +AG + V T + P +P I + K+L+SW+
Sbjct: 4228 TGLQPWTQCEYKIYTWNSAGHTCSSWNVV-RTLQAPPEGLSPPVISYVSMNPQKLLISWI 4286
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
PP NG++ Y L R E + P T ++ P +T+ + + A T
Sbjct: 4287 PPEQSNGIIQSYRLQ-------RNEMLYPFSFDPVTFNYTDEELLPFSTYSYALQACTS- 4338
Query: 466 GEGEATRVVTVLPSDSVPARIT 487
G ++ ++ ++ P+ ++
Sbjct: 4339 GGCSTSKPTSITTLEAAPSEVS 4360
Score = 33.5 bits (73), Expect = 4.3
Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 13/144 (9%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
ED+P P A + ++ S S VSW P NG++ Y + + +
Sbjct: 2238 EDIPEGVP-APKAHSYSPDSFNVSWTEPEYP--NGVITSYGLYL---------DGILIHN 2285
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
S L G ++ +S V A TA G + V T E P ++ K
Sbjct: 2286 SSELSYRAYGFAPWSLHSFRVQACTAKGCALGPL-VENRTLEAPPEGTVNVFVKTQGSRK 2344
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSV 423
V W P PNG+L L+ +
Sbjct: 2345 AHVRWEAPFRPNGLLTHSVLFTGI 2368
>U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding
protein-C protein.
Length = 1274
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 7/231 (3%)
Query: 525 ESTLRKNVSSDGTL-TISMTQSADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPILAVV 582
E +R + D ++ T+ + D G YT +V+N G D+V TV+V VP P +
Sbjct: 722 EGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKIS 781
Query: 583 DSYADSLHLQWSDQG-DGGSPILGYVINYKREHG-DWEELQVE-AGTSEHVLPNLWCGTR 639
+ DS +QW DGG PILGY++ K++ W L + H + G
Sbjct: 782 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 841
Query: 640 YQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
Y++ + A N IG P + P +P H + ++ TTV++ W G G+
Sbjct: 842 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 901
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +EY +W + + V L A R+ AHN AG
Sbjct: 902 DGYSVEYCPEGCSEWVAALQGLTEHTSIL-VKDLPTGARLLFRVRAHNMAG 951
Score = 65.3 bits (152), Expect = 1e-09
Identities = 94/385 (24%), Positives = 140/385 (36%), Gaps = 22/385 (5%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
DVP P A + + + S V WEPP G IL GY + W N D +
Sbjct: 770 DVPDAP-AAPKISNVGEDSCTVQWEPPAYDGGQPIL-GYILERKKKKSYRWMRLNFDLIQ 827
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y + V A A G + PS P + S
Sbjct: 828 ELSHEARRMIEGVV----YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 883
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+ + W PP G L GY++ +G E S P A
Sbjct: 884 TTVSLKWRPPERVGAGGLDGYSV--EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 941
Query: 457 FWVSASTRLGEGE---ATRVVTVLPSDSVPA-RITSFSRNIVTPWK-ENISLSCNKVGVP 511
F V A G G T VTV P ++ R + E ++L G P
Sbjct: 942 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1001
Query: 512 APATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P TWT G L E +N +D L I + SG Y +V + D+ T ++
Sbjct: 1002 RPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1061
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQGD-GGSPILGYVI-NYKREHGDWEELQVEAGT 626
V P PP L V D++ ++ L+W D G + + GY + ++ +W +
Sbjct: 1062 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRR 1121
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG 651
+ V+P L G Y + + N +G
Sbjct: 1122 THCVVPELIIGNGYYFRVFSQNMVG 1146
Score = 54.0 bits (124), Expect = 3e-06
Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 27/196 (13%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ P ++ + + + W P Y G PI+ YI++ K+ W +I
Sbjct: 771 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLI---Q 827
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD---VRVEAKSS 183
S + + Y +R+ A N +G S PS Q +P GPP + + VE S
Sbjct: 828 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSD 883
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGF------------QELNSNSTVLIASGPGGAS--Y 229
T + + W PP+R + G + GY V + Q L ++++L+ P GA +
Sbjct: 884 TTVSLKWRPPER-VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 942
Query: 230 TVRTVEGAGTARSRTT 245
VR AG TT
Sbjct: 943 RVRAHNMAGPGAPVTT 958
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C G P P +W NG+ L R + S G LT+ + + D G Y C N+
Sbjct: 1200 LCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1259
Query: 560 GRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1260 GEARCECRLEVRVP 1273
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
PPQD+RV + + W+PPQ D+ N + GY V
Sbjct: 1068 PPQDLRVTDAWGLNVALEWKPPQ-DVGNTELWGYTV 1102
>AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein C,
cardiac protein.
Length = 1273
Score = 82.6 bits (195), Expect = 7e-15
Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 7/231 (3%)
Query: 525 ESTLRKNVSSDGTL-TISMTQSADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPILAVV 582
E +R + D ++ T+ + D G YT +V+N G D+V TV+V VP P +
Sbjct: 721 EGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKIS 780
Query: 583 DSYADSLHLQWSDQG-DGGSPILGYVINYKREHG-DWEELQVE-AGTSEHVLPNLWCGTR 639
+ DS +QW DGG PILGY++ K++ W L + H + G
Sbjct: 781 NVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVV 840
Query: 640 YQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGI 698
Y++ + A N IG P + P +P H + ++ TTV++ W G G+
Sbjct: 841 YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGL 900
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ +EY +W + + V L A R+ AHN AG
Sbjct: 901 DGYSVEYCPEGCSEWVAALQGLTEHTSIL-VKDLPTGARLLFRVRAHNMAG 950
Score = 65.3 bits (152), Expect = 1e-09
Identities = 94/385 (24%), Positives = 140/385 (36%), Gaps = 22/385 (5%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
DVP P A + + + S V WEPP G IL GY + W N D +
Sbjct: 769 DVPDAP-AAPKISNVGEDSCTVQWEPPAYDGGQPIL-GYILERKKKKSYRWMRLNFDLIQ 826
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y + V A A G + PS P + S
Sbjct: 827 ELSHEARRMIEGVV----YEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSD 882
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+ + W PP G L GY++ +G E S P A
Sbjct: 883 TTVSLKWRPPERVGAGGLDGYSV--EYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLL 940
Query: 457 FWVSASTRLGEGE---ATRVVTVLPSDSVPA-RITSFSRNIVTPWK-ENISLSCNKVGVP 511
F V A G G T VTV P ++ R + E ++L G P
Sbjct: 941 FRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKP 1000
Query: 512 APATTWTMNGVGL--ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE 569
P TWT G L E +N +D L I + SG Y +V + D+ T ++
Sbjct: 1001 RPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1060
Query: 570 VKVPPQPP-ILAVVDSYADSLHLQWSDQGD-GGSPILGYVI-NYKREHGDWEELQVEAGT 626
V P PP L V D++ ++ L+W D G + + GY + ++ +W +
Sbjct: 1061 VVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRR 1120
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG 651
+ V+P L G Y + + N +G
Sbjct: 1121 THCVVPELIIGNGYYFRVFSQNMVG 1145
Score = 54.0 bits (124), Expect = 3e-06
Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 27/196 (13%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGS 126
VP+ P ++ + + + W P Y G PI+ YI++ K+ W +I
Sbjct: 770 VPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLI---Q 826
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD---VRVEAKSS 183
S + + Y +R+ A N +G S PS Q +P GPP + + VE S
Sbjct: 827 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPF----MPIGPPSEPTHLAVEDVSD 882
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGF------------QELNSNSTVLIASGPGGAS--Y 229
T + + W PP+R + G + GY V + Q L ++++L+ P GA +
Sbjct: 883 TTVSLKWRPPER-VGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLF 941
Query: 230 TVRTVEGAGTARSRTT 245
VR AG TT
Sbjct: 942 RVRAHNMAGPGAPVTT 957
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C G P P +W NG+ L R + S G LT+ + + D G Y C N+
Sbjct: 1199 LCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQ 1258
Query: 560 GRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1259 GEARCECRLEVRVP 1272
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 172 PPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
PPQD+RV + + W+PPQ D+ N + GY V
Sbjct: 1067 PPQDLRVTDAWGLNVALEWKPPQ-DVGNTELWGYTV 1101
>X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein.
Length = 1123
Score = 81.8 bits (193), Expect = 1e-14
Identities = 70/250 (28%), Positives = 103/250 (41%), Gaps = 10/250 (4%)
Query: 509 GVPAPATTWTMNGVGL-ESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEV 564
G P P W+ + E + R S TL I + + DSG Y +++N G
Sbjct: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
Query: 565 TYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQG-DGGSPILGYVINYKREHGD-WEELQ 621
+ V+V P PP+ V D + W DGGSPILGY I K++ W L
Sbjct: 611 SIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
Query: 622 VEAGTSEHVLPNLWC-GTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ P G Y++ I A N IG P + V P + ++
Sbjct: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVT 730
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
TTVT+ W G G+ +V+EY W +V+N + F+++GL A
Sbjct: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW-IVANKDLIDKTKFTITGLPTDAKIF 789
Query: 740 LRITAHNNAG 749
+R+ A N AG
Sbjct: 790 VRVKAVNAAG 799
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
Query: 88 ISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P Y G SPI+ Y ++ K+ S W + T+ + + +Y +RI
Sbjct: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC---KETTFEPKKMIEGVAYEVRI 694
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
A N +G S+PS P + V S PP + V++ + T + + W PP
Sbjct: 695 FAVNAIGISKPSMPSRPFVPLAVTS-PPTLLTVDSVTDTTVTMRWRPP 741
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/389 (20%), Positives = 138/389 (35%), Gaps = 30/389 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
D P PP A + ++WEPP G + IL GY + W N D
Sbjct: 618 DFPD-PPVAPTVTEVGDDWCIMNWEPPAYDGGSPIL-GYFIERKKKQSSRWMRLNFDLCK 675
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y V + A A G + P V S P + +
Sbjct: 676 ETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRS----PPR 452
+ + W PP L GY L EGT +++ L +T + P
Sbjct: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCF------EGTEDWIVANKDLIDKTKFTITGLPTD 785
Query: 453 ATHQFWVSASTRLGEGEATRVVT-VLPSDSVPARITSFSRNIVTPWKENISLSCNKV--- 508
A V A G E +L + + R++ + + + N V
Sbjct: 786 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 845
Query: 509 -GVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TW +G ++ +N +D + I + + SG Y V+ + +
Sbjct: 846 QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 905
Query: 566 YTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVI-NYKREHGDWEELQV 622
+++ P PP I+ + D + +++ L W+ DG + I GY I ++ +W +
Sbjct: 906 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 965
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ + L G Y + + N G
Sbjct: 966 HYHRTSATITELVIGNEYYFRVFSENMCG 994
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA--DSGNYTCSVE 556
N +L+C+ G P P TW N V + R + S+ G T+ + + + D G Y C
Sbjct: 1045 NATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1104
Query: 557 NIHGRDEVTYTVEVKVPPQ 575
N G E+ +EVKV Q
Sbjct: 1105 NDLGTVEIECKLEVKVIAQ 1123
Score = 38.7 bits (86), Expect = 0.11
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
Query: 53 DSKVTVD--LRIGSLSHQV---PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ 106
D +V VD + S+ Q+ P P+ +++ D + ++WT P GN+ I Y +Q
Sbjct: 892 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 951
Query: 107 YKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSE 155
+ T VI TSA++ L Y+ R+ +EN G SE
Sbjct: 952 KADKKSMEWFT---VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 997
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
GPPQ V++E + +TW PP+ D N I GY +
Sbjct: 915 GPPQIVKIEDVWGENVALTWTPPKDD-GNAAITGYTI 950
>BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein.
Length = 1120
Score = 81.8 bits (193), Expect = 1e-14
Identities = 70/250 (28%), Positives = 103/250 (41%), Gaps = 10/250 (4%)
Query: 509 GVPAPATTWTMNGVGL-ESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEV 564
G P P W+ + E + R S TL I + + DSG Y +++N G
Sbjct: 525 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 584
Query: 565 TYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQG-DGGSPILGYVINYKREHGD-WEELQ 621
+ V+V P PP+ V D + W DGGSPILGY I K++ W L
Sbjct: 585 SIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 644
Query: 622 VEAGTSEHVLPNLWC-GTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ P G Y++ I A N IG P + V P + ++
Sbjct: 645 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVT 704
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
TTVT+ W G G+ +V+EY W +V+N + F+++GL A
Sbjct: 705 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW-IVANKDLIDKTKFTITGLPTDAKIF 763
Query: 740 LRITAHNNAG 749
+R+ A N AG
Sbjct: 764 VRVKAVNAAG 773
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
Query: 88 ISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P Y G SPI+ Y ++ K+ S W + T+ + + +Y +RI
Sbjct: 612 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC---KETTFEPKKMIEGVAYEVRI 668
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
A N +G S+PS P + V S PP + V++ + T + + W PP
Sbjct: 669 FAVNAIGISKPSMPSRPFVPLAVTS-PPTLLTVDSVTDTTVTMRWRPP 715
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/389 (20%), Positives = 138/389 (35%), Gaps = 30/389 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
D P PP A + ++WEPP G + IL GY + W N D
Sbjct: 592 DFPD-PPVAPTVTEVGDDWCIMNWEPPAYDGGSPIL-GYFIERKKKQSSRWMRLNFDLCK 649
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y V + A A G + P V S P + +
Sbjct: 650 ETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 705
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRS----PPR 452
+ + W PP L GY L EGT +++ L +T + P
Sbjct: 706 TTVTMRWRPPDHIGAAGLDGYVLEYCF------EGTEDWIVANKDLIDKTKFTITGLPTD 759
Query: 453 ATHQFWVSASTRLGEGEATRVVT-VLPSDSVPARITSFSRNIVTPWKENISLSCNKV--- 508
A V A G E +L + + R++ + + + N V
Sbjct: 760 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 819
Query: 509 -GVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TW +G ++ +N +D + I + + SG Y V+ + +
Sbjct: 820 QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 879
Query: 566 YTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVI-NYKREHGDWEELQV 622
+++ P PP I+ + D + +++ L W+ DG + I GY I ++ +W +
Sbjct: 880 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 939
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ + L G Y + + N G
Sbjct: 940 HYHRTSATITELVIGNEYYFRVFSENMCG 968
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA--DSGNYTCSVE 556
N +L+C+ G P P TW N V + R + S+ G T+ + + + D G Y C
Sbjct: 1019 NATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1078
Query: 557 NIHGRDEVTYTVEVKV 572
N G E+ +EVKV
Sbjct: 1079 NDLGTVEIECKLEVKV 1094
Score = 38.7 bits (86), Expect = 0.11
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
Query: 53 DSKVTVD--LRIGSLSHQV---PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ 106
D +V VD + S+ Q+ P P+ +++ D + ++WT P GN+ I Y +Q
Sbjct: 866 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 925
Query: 107 YKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSE 155
+ T VI TSA++ L Y+ R+ +EN G SE
Sbjct: 926 KADKKSMEWFT---VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 971
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
GPPQ V++E + +TW PP+ D N I GY +
Sbjct: 889 GPPQIVKIEDVWGENVALTWTPPKDD-GNAAITGYTI 924
>BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein C,
slow type protein.
Length = 1123
Score = 81.8 bits (193), Expect = 1e-14
Identities = 70/250 (28%), Positives = 103/250 (41%), Gaps = 10/250 (4%)
Query: 509 GVPAPATTWTMNGVGL-ESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEV 564
G P P W+ + E + R S TL I + + DSG Y +++N G
Sbjct: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
Query: 565 TYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQG-DGGSPILGYVINYKREHGD-WEELQ 621
+ V+V P PP+ V D + W DGGSPILGY I K++ W L
Sbjct: 611 SIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
Query: 622 VEAGTSEHVLPNLWC-GTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ P G Y++ I A N IG P + V P + ++
Sbjct: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVT 730
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQ 739
TTVT+ W G G+ +V+EY W +V+N + F+++GL A
Sbjct: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW-IVANKDLIDKTKFTITGLPTDAKIF 789
Query: 740 LRITAHNNAG 749
+R+ A N AG
Sbjct: 790 VRVKAVNAAG 799
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 6/108 (5%)
Query: 88 ISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P Y G SPI+ Y ++ K+ S W + T+ + + +Y +RI
Sbjct: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC---KETTFEPKKMIEGVAYEVRI 694
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPP 193
A N +G S+PS P + V S PP + V++ + T + + W PP
Sbjct: 695 FAVNAIGISKPSMPSRPFVPLAVTS-PPTLLTVDSVTDTTVTMRWRPP 741
Score = 45.2 bits (102), Expect = 0.001
Identities = 81/389 (20%), Positives = 138/389 (35%), Gaps = 30/389 (7%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
D P PP A + ++WEPP G + IL GY + W N D
Sbjct: 618 DFPD-PPVAPTVTEVGDDWCIMNWEPPAYDGGSPIL-GYFIERKKKQSSRWMRLNFDLCK 675
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y V + A A G + P V S P + +
Sbjct: 676 ETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
Query: 398 NKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRS----PPR 452
+ + W PP L GY L EGT +++ L +T + P
Sbjct: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCF------EGTEDWIVANKDLIDKTKFTITGLPTD 785
Query: 453 ATHQFWVSASTRLGEGEATRVVT-VLPSDSVPARITSFSRNIVTPWKENISLSCNKV--- 508
A V A G E +L + + R++ + + + N V
Sbjct: 786 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 845
Query: 509 -GVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TW +G ++ +N +D + I + + SG Y V+ + +
Sbjct: 846 QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 905
Query: 566 YTVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVI-NYKREHGDWEELQV 622
+++ P PP I+ + D + +++ L W+ DG + I GY I ++ +W +
Sbjct: 906 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 965
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+ + L G Y + + N G
Sbjct: 966 HYHRTSATITELVIGNEYYFRVFSENMCG 994
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNV-SSDGTLTISMTQSA--DSGNYTCSVE 556
N +L+C+ G P P TW N V + R + S+ G T+ + + + D G Y C
Sbjct: 1045 NATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1104
Query: 557 NIHGRDEVTYTVEVKVPPQ 575
N G E+ +EVKV Q
Sbjct: 1105 NDLGTVEIECKLEVKVIAQ 1123
Score = 38.7 bits (86), Expect = 0.11
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
Query: 53 DSKVTVD--LRIGSLSHQV---PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQ 106
D +V VD + S+ Q+ P P+ +++ D + ++WT P GN+ I Y +Q
Sbjct: 892 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 951
Query: 107 YKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSE 155
+ T VI TSA++ L Y+ R+ +EN G SE
Sbjct: 952 KADKKSMEWFT---VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 997
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
GPPQ V++E + +TW PP+ D N I GY +
Sbjct: 915 GPPQIVKIEDVWGENVALTWTPPKDD-GNAAITGYTI 950
>AL354664-1|CAH71310.1| 3063|Homo sapiens collagen type XII alpha 1
protein.
Length = 3063
Score = 81.0 bits (191), Expect = 2e-14
Identities = 95/409 (23%), Positives = 174/409 (42%), Gaps = 57/409 (13%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ +V P+N++V D+ + + +I+WTQ ++ Y + Y+ ++V P
Sbjct: 719 TEEVKGAPRNLKVTDETTDSFKITWTQ---APGRVLRYRIIYRPVA---GGESREVTTPP 772
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+ +++NL P T Y + +I E G P P+ E G P+D+RV +++
Sbjct: 773 NQRRRTLENLIPDTKYEVSVIPEYFSG---PGTPLTGNAATEEVRGNPRDLRVSDPTTST 829
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W G + Y V + + GG + V TV G T T
Sbjct: 830 MKLSWSGAP-----GKVKQYLVTYTPV-----------AGGETQEV-TVRGDTT---NTV 869
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L GL++ YA+ V A + +E+ S P L ++ S+ W
Sbjct: 870 LQGLKEGTQYALSVTALYA-SGAGDALFGEGTTLEERGS--PQDLVTKDITDTSIGAYWT 926
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTVCAF 363
P G+++GYRV++ + Y + D K + +HT + L+ T Y ++V A
Sbjct: 927 SAP-----GMVRGYRVSWKSL---YDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFAT 978
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
++G+G P+ ++ +K + N + V+W P +P G +V Y +
Sbjct: 979 YSSGEG---EPLTGDATTELSQDSKTLKVDEETENTMRVTWKP--AP-GKVVNYRVVY-- 1030
Query: 424 IEDGREEGTHKRMLS---PSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
R G K+M++ P+ S R P+ T+ V ++GEG+
Sbjct: 1031 ----RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK 1075
Score = 76.6 bits (180), Expect = 5e-13
Identities = 108/445 (24%), Positives = 183/445 (41%), Gaps = 51/445 (11%)
Query: 58 VDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPST 117
++ + ++ + PK++ + S + +W+ AG + + +Y + YKEA T
Sbjct: 620 IEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSP--AGEN-VFSYHITYKEAAGDDEVT 676
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
V+ P S TS + +L+P T Y + + AE G S P + TTEEV G P++++
Sbjct: 677 ---VVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEE--TTEEV-KGAPRNLK 730
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
V +++ +TW G +L Y + ++ + GG S V T
Sbjct: 731 VTDETTDSFKITWTQAP-----GRVLRYRIIYRPV-----------AGGESREVTTPPN- 773
Query: 238 GTARSRTTLSGLQKHAAYAV-VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
+ R TL L Y V V+ Y S E+V P L+ + +
Sbjct: 774 ---QRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAAT---EEVRGNPRD-LRVSDPT 826
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+ ++++SW P G ++ Y VTY PV G VT + +T L GL+ T Y
Sbjct: 827 TSTMKLSWSGAP-----GKVKQYLVTYTPVAG--GETQEVTVRGDTTNTVLQGLKEGTQY 879
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+++V A A+G G EE +P D+ + I W +S G++ G
Sbjct: 880 ALSVTALYASGAGDALFGEGTTLEE--RGSPQDLVTKDITDTSIGAYW---TSAPGMVRG 934
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATR--VV 474
Y + + D + G ++ L + P ++ V A+ GEGE
Sbjct: 935 YRVSWKSLYDDVDTG--EKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDAT 992
Query: 475 TVLPSDSVPARITSFSRNIV-TPWK 498
T L DS ++ + N + WK
Sbjct: 993 TELSQDSKTLKVDEETENTMRVTWK 1017
Score = 59.7 bits (138), Expect = 6e-08
Identities = 77/291 (26%), Positives = 120/291 (41%), Gaps = 40/291 (13%)
Query: 72 MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSAS 131
+ +N++V + ++ + W P G P++ Y V Y + PS + ++VPG+
Sbjct: 1936 LARNVQVYNPTPNSLDVRW-DPAPG--PVLQYRVVYSPVDGTRPS--ESIVVPGNTRMVH 1990
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
++ L P T Y + ++A G+ PS P Q T +P P+++RV +++ L V W
Sbjct: 1991 LERLIPDTLYSVNLVALYSDGEGNPS-PAQGRT---LPRSGPRNLRVFGETTNSLSVAW- 2045
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
D +G + Y + + + TV G YT TV G R+ L LQ
Sbjct: 2046 ----DHADGPVQQYRIIY-----SPTV----GDPIDEYT--TVPG---RRNNVILQPLQP 2087
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRG 311
Y + V A V LPP + + RVSW+P P
Sbjct: 2088 DTPYKITVIAVYEDGDGGHLTGNG----RTVGLLPPQNIHISDEWYTRFRVSWDPSP--- 2140
Query: 312 RNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
+ +L GY++ Y PV E V + S TL L T Y V V A
Sbjct: 2141 -SPVL-GYKIVYKPVGSNEPMEAFVGEMTS---YTLHNLNPSTTYDVNVYA 2186
Score = 57.2 bits (132), Expect = 3e-07
Identities = 85/368 (23%), Positives = 152/368 (41%), Gaps = 57/368 (15%)
Query: 75 NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
++ + D T+ + W QP G + YI+ YK ++ P+ P++V + +V + +
Sbjct: 1479 SLNIYDVGPTTMHVQW-QPVGGAT---GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 1534
Query: 135 LQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQ 194
L P T Y + + A SEP +VT +P PQD+++ + + + V WEP
Sbjct: 1535 LVPNTEYAVTVQAVLHDLTSEPVTVREVT----LPLPRPQDLKLRDVTHSTMNVFWEPVP 1590
Query: 195 RDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAA 254
G + Y V ++ + V+ VE + + T+L L
Sbjct: 1591 -----GKVRKYIVRYKTPEED---------------VKEVE-VDRSETSTSLKDLFSQTL 1629
Query: 255 YAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNG 314
Y V V A + VP+ P L+ ++S+ R +W+ G +
Sbjct: 1630 YTVSVSAVHDEGESPPVTAQETT--RPVPA--PTNLKITEVTSEGFRGTWD----HGASD 1681
Query: 315 ILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTVCAF---TAAGDG 369
+ YR+T+AP +G+ D + ++G TL L T Y V++ A + D
Sbjct: 1682 V-SLYRITWAP----FGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDD 1736
Query: 370 V----RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ R P+ T + S P +++ ++ N + V W P S G + Y + Y
Sbjct: 1737 LIGSERTLPIL--TTQAPKSGPRNLQVYNATSNSLTVKWDPAS---GRVQKYRITYQPST 1791
Query: 425 EDGREEGT 432
+G E+ T
Sbjct: 1792 GEGNEQTT 1799
Score = 56.4 bits (130), Expect = 5e-07
Identities = 74/303 (24%), Positives = 120/303 (39%), Gaps = 41/303 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++++ D T+ + W +P G + YIV+YK E ++V V S TS S+
Sbjct: 1569 PQDLKLRDVTHSTMNVFW-EPVPGK--VRKYIVRYKTPEED----VKEVEVDRSETSTSL 1621
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
++L T Y + + A + G+S P + TT VP+ P ++++ +S TW+
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQE--TTRPVPA--PTNLKITEVTSEGFRGTWDH 1677
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
D+ S I P G+S + T+ + L +
Sbjct: 1678 GASDV------------------SLYRITWAPFGSSDKMETILNGD--ENTLVFENLNPN 1717
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXME----DVPSLPPGALQCNALSSQSVRVSWEPPP 308
Y V + A + P P LQ +S S+ V W+P
Sbjct: 1718 TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA- 1776
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+G +Q YR+TY P T GNE T L L+ T Y++TV + G+
Sbjct: 1777 ----SGRVQKYRITYQPSTG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 369 GVR 371
G R
Sbjct: 1832 GGR 1834
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/147 (25%), Positives = 72/147 (48%), Gaps = 14/147 (9%)
Query: 63 GSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
G + ++ + K ++V ++ T++++W +P G ++NY V Y+ +
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK--VVNYRVVYRPHGRGKQMVAK--- 1042
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
VP +VTS ++ LQP T+Y + ++ ++G+ + Q TT S P++++ +
Sbjct: 1043 VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQG-SGTTASRFKS--PRNLKTSDPT 1099
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGF 209
+ VTWEP G + GY V F
Sbjct: 1100 MSSFRVTWEPAP-----GEVKGYKVTF 1121
Score = 46.4 bits (105), Expect = 6e-04
Identities = 78/342 (22%), Positives = 133/342 (38%), Gaps = 45/342 (13%)
Query: 65 LSHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV 123
L+ Q P+ P+N++V + S ++ + W P +G + Y + Y+ P + Q +
Sbjct: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGR--VQKYRITYQ--PSTGEGNEQTTTI 1801
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
G S +Q L+P T Y I + E + T+ P +++RV S+
Sbjct: 1802 GGRQNSVVLQKLKPDTPY--TITVSSLYPDGEGGRMTGRGKTK--PLNTVRNLRVYDPST 1857
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
+ L V W+ + GN Y + + L+ PG +Y +
Sbjct: 1858 STLNVRWDHAE-----GNPRQYKLFYAPAAGGPEELVPI-PGNTNYAI------------ 1899
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVS 303
L LQ +Y V V + M + +Q + S+ V
Sbjct: 1900 --LRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR----NVQVYNPTPNSLDVR 1953
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W+P P +LQ YRV Y+PV +E V + + L L T YSV + A
Sbjct: 1954 WDPAP----GPVLQ-YRVVYSPVDGTRPSESIVVPGNTRM-VHLERLIPDTLYSVNLVAL 2007
Query: 364 TAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSW 404
+ G+G +P T +P S P +++ + N + V+W
Sbjct: 2008 YSDGEG-NPSPAQGRT---LPRSGPRNLRVFGETTNSLSVAW 2045
Score = 45.2 bits (102), Expect = 0.001
Identities = 66/296 (22%), Positives = 110/296 (37%), Gaps = 38/296 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++ D +I WT + + Y V +K + T +K + P +
Sbjct: 908 PQDLVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDD-VDTGEKNL-PEDAIHTMI 962
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP T Y + + A G+ EP + T E+ S + ++V+ ++ + VTW+P
Sbjct: 963 ENLQPETKYRISVFATYSSGEGEP---LTGDATTEL-SQDSKTLKVDEETENTMRVTWKP 1018
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G ++ Y V ++ + ++A P + TV L LQ
Sbjct: 1019 AP-----GKVVNYRVVYRP-HGRGKQMVAKVPPTVTSTV--------------LKRLQPQ 1058
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y + V P L+ + + S RV+WEP P
Sbjct: 1059 TTYDITVLPIYKMGEGKLRQGSGTTASR---FKSPRNLKTSDPTMSSFRVTWEPAP---- 1111
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
G ++GY+VT+ P D + V L LR T Y V V G+
Sbjct: 1112 -GEVKGYKVTFHPTGDDRRLGELVVGPYDNT-VVLEELRAGTTYKVNVFGMFDGGE 1165
Score = 45.2 bits (102), Expect = 0.001
Identities = 131/597 (21%), Positives = 226/597 (37%), Gaps = 74/597 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
E P N+ + ++ R+ ++SWT P + + Y V+Y P S Q+ V TS
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPP---SDSVDRYKVEY--YPVS-GGKRQEFYVSRMETST 1439
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+++L+P T Y + + + + + E S+P++ TE+ P + + T + V W
Sbjct: 1440 VLKDLKPETEYVVNVYS---VVEDEYSEPLK--GTEKTLPVPVVSLNIYDVGPTTMHVQW 1494
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+P G GY + ++ + VR G + L+ L
Sbjct: 1495 QPV------GGATGYILSYKPVKDTEPT--------RPKEVR----LGPTVNDMQLTDLV 1536
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
+ YAV VQA +P P L+ ++ ++ V WEP P +
Sbjct: 1537 PNTEYAVTVQA----VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK 1592
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
R I++ Y+ V + V S T+L L T Y+V+V A G+
Sbjct: 1593 VRKYIVR-YKTPEEDVKE-------VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE-- 1642
Query: 371 RAAPVYC-HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL------VGYTLYMSV 423
+ PV T VP AP ++K + +W +S + G + M
Sbjct: 1643 -SPPVTAQETTRPVP-APTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
I +G E L+P+T+ +E S + A + + +G ++T S P
Sbjct: 1701 ILNGDENTLVFENLNPNTI-YEVSIT---AIYPDESESDDLIGSERTLPILTTQAPKSGP 1756
Query: 484 ARITSF---SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
+ + S ++ W + S K + +T G G E T + +
Sbjct: 1757 RNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPST----GEGNEQT--TTIGGRQNSVV 1809
Query: 541 SMTQSADSGNYTCSVENIHGRDE-VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQG 597
D+ YT +V +++ E T K P + L V D +L+++W D
Sbjct: 1810 LQKLKPDT-PYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW-DHA 1867
Query: 598 DGGSPILGYVINYKREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
+G Y + Y G EEL + T+ +L NL T Y + + G G
Sbjct: 1868 EGNP--RQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDG 1922
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+NI + D+ ++SW SP++ Y + YK + P + V G +TS ++
Sbjct: 2119 PQNIHISDEWYTRFRVSWDP---SPSPVLGYKIVYKPVGSN---EPMEAFV-GEMTSYTL 2171
Query: 133 QNLQPATSYHLRIIAENRLGQSEP 156
NL P+T+Y + + A+ G S P
Sbjct: 2172 HNLNPSTTYDVNVYAQYDSGLSVP 2195
Score = 43.6 bits (98), Expect = 0.004
Identities = 81/380 (21%), Positives = 142/380 (37%), Gaps = 35/380 (9%)
Query: 285 LPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLH 344
+PP L + ++S + +W P G N + Y +TY +E V + S
Sbjct: 633 VPPKDLSFSEVTSYGFKTNWSPA---GEN--VFSYHITYKEAAG--DDEVTVVEPASSTS 685
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
LS L+ T Y V V A G + A T E+V AP ++K + + ++W
Sbjct: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGE--ETTEEVKGAPRNLKVTDETTDSFKITW 743
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
+P VL +Y V G + + +P T + T ++ VS
Sbjct: 744 --TQAPGRVLRYRIIYRPV-----AGGESREVTTPPNQRRRTLENLIPDT-KYEVSVIPE 795
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G T + ++ V R + P + LS + G P + + +
Sbjct: 796 YFSGPGTPLTGNAATEEV--RGNPRDLRVSDPTTSTMKLSWS--GAPGKVKQYLVTYTPV 851
Query: 525 ESTLRKNVSSDGTLTISMTQSADSG-NYTCSVENIH--GRDEVTY----TVEVKVPPQPP 577
+ V+ G T ++ Q G Y SV ++ G + + T+E + PQ
Sbjct: 852 AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD- 910
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE--ELQVEAGTSEHVLPNLW 635
L D S+ W+ + GY +++K + D + E + ++ NL
Sbjct: 911 -LVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQ 966
Query: 636 CGTRYQLYITAFNRIGTGLP 655
T+Y++ + A G G P
Sbjct: 967 PETKYRISVFATYSSGEGEP 986
Score = 41.1 bits (92), Expect = 0.021
Identities = 81/347 (23%), Positives = 135/347 (38%), Gaps = 47/347 (13%)
Query: 74 KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI-VPGSVTSASV 132
+N+RV D + T+ + W +A +P QYK P++++ +PG+ A +
Sbjct: 1848 RNLRVYDPSTSTLNVRWD--HAEGNPR-----QYKLFYAPAAGGPEELVPIPGNTNYAIL 1900
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP TSY + ++ G + T + G ++V+V + L V W+P
Sbjct: 1901 RNLQPDTSYTVTVVPVYTEGDGGRTS----DTGRTLMRGLARNVQVYNPTPNSLDVRWDP 1956
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G +L Y V + ++ PG R V L L
Sbjct: 1957 AP-----GPVLQYRVVYSPVDGTRPSESIVVPG----NTRMVH----------LERLIPD 1997
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y+V + A S +P P L+ ++ S+ V+W+
Sbjct: 1998 TLYSVNLVALYSDGEGNPSPAQG----RTLPRSGPRNLRVFGETTNSLSVAWD-----HA 2048
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
+G +Q YR+ Y+P T ++ T + L L+ T Y +TV A GDG
Sbjct: 2049 DGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHL 2107
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
T +P P +I + + VSW P SP ++GY +
Sbjct: 2108 TG-NGRTVGLLP--PQNIHISDEWYTRFRVSWDPSPSP---VLGYKI 2148
Score = 39.9 bits (89), Expect = 0.049
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 567 TVEVKV-PPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWEELQVEA 624
++E +V PP ++D +++H+ W+ D PI+GY I G +E + A
Sbjct: 20 SIEAEVDPPSDLNFKIIDE--NTVHMSWAKPVD---PIVGYRITVDPTTDGPTKEFTLSA 74
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
T+E +L L T Y + IT+++ + +P + T PV+ K + +
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGK-TEIQKC 133
Query: 683 TVTVWLD 689
+V+ W D
Sbjct: 134 SVSAWTD 140
Score = 38.3 bits (85), Expect = 0.15
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 58 VDLRIGSL--SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VD ++G L +V E P N+ ++ S+ ++++W SP+ Y V P +
Sbjct: 320 VDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP---SPSPVTGYKVIL--TPMTAG 374
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
S + V T+ SV++L T Y + + A + SEP ++ T +V +
Sbjct: 375 SRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRG 434
Query: 176 VRVEA 180
V ++A
Sbjct: 435 VDIKA 439
Score = 37.5 bits (83), Expect = 0.26
Identities = 46/224 (20%), Positives = 86/224 (38%), Gaps = 15/224 (6%)
Query: 525 ESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENI-HGRDEVTYTV-EVKVP-PQPPILA 580
E T K V T+ + +T + Y +V+ + H TV EV +P P+P L
Sbjct: 1514 EPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLK 1573
Query: 581 VVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRY 640
+ D ++++ W + Y++ YK D +E++V+ + L +L+ T Y
Sbjct: 1574 LRDVTHSTMNVFWEPVP---GKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLY 1630
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ ++A + G P + T VP + + T + +W G +
Sbjct: 1631 TVSVSAVHDEGESPP--VTAQETTRPVPAPTN----LKITEVTSEGFRGTWDHGASDVSL 1684
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I + + + E L P Y++ ITA
Sbjct: 1685 YRITWAPFGSSD--KMETILNGDENTLVFENLNPNTIYEVSITA 1726
>AL096771-3|CAI19908.1| 3063|Homo sapiens collagen type XII alpha 1
protein.
Length = 3063
Score = 81.0 bits (191), Expect = 2e-14
Identities = 95/409 (23%), Positives = 174/409 (42%), Gaps = 57/409 (13%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ +V P+N++V D+ + + +I+WTQ ++ Y + Y+ ++V P
Sbjct: 719 TEEVKGAPRNLKVTDETTDSFKITWTQ---APGRVLRYRIIYRPVA---GGESREVTTPP 772
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+ +++NL P T Y + +I E G P P+ E G P+D+RV +++
Sbjct: 773 NQRRRTLENLIPDTKYEVSVIPEYFSG---PGTPLTGNAATEEVRGNPRDLRVSDPTTST 829
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W G + Y V + + GG + V TV G T T
Sbjct: 830 MKLSWSGAP-----GKVKQYLVTYTPV-----------AGGETQEV-TVRGDTT---NTV 869
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L GL++ YA+ V A + +E+ S P L ++ S+ W
Sbjct: 870 LQGLKEGTQYALSVTALYA-SGAGDALFGEGTTLEERGS--PQDLVTKDITDTSIGAYWT 926
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTVCAF 363
P G+++GYRV++ + Y + D K + +HT + L+ T Y ++V A
Sbjct: 927 SAP-----GMVRGYRVSWKSL---YDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFAT 978
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
++G+G P+ ++ +K + N + V+W P +P G +V Y +
Sbjct: 979 YSSGEG---EPLTGDATTELSQDSKTLKVDEETENTMRVTWKP--AP-GKVVNYRVVY-- 1030
Query: 424 IEDGREEGTHKRMLS---PSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
R G K+M++ P+ S R P+ T+ V ++GEG+
Sbjct: 1031 ----RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK 1075
Score = 76.6 bits (180), Expect = 5e-13
Identities = 108/445 (24%), Positives = 183/445 (41%), Gaps = 51/445 (11%)
Query: 58 VDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPST 117
++ + ++ + PK++ + S + +W+ AG + + +Y + YKEA T
Sbjct: 620 IEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSP--AGEN-VFSYHITYKEAAGDDEVT 676
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
V+ P S TS + +L+P T Y + + AE G S P + TTEEV G P++++
Sbjct: 677 ---VVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEE--TTEEV-KGAPRNLK 730
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
V +++ +TW G +L Y + ++ + GG S V T
Sbjct: 731 VTDETTDSFKITWTQAP-----GRVLRYRIIYRPV-----------AGGESREVTTPPN- 773
Query: 238 GTARSRTTLSGLQKHAAYAV-VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
+ R TL L Y V V+ Y S E+V P L+ + +
Sbjct: 774 ---QRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAAT---EEVRGNPRD-LRVSDPT 826
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+ ++++SW P G ++ Y VTY PV G VT + +T L GL+ T Y
Sbjct: 827 TSTMKLSWSGAP-----GKVKQYLVTYTPVAG--GETQEVTVRGDTTNTVLQGLKEGTQY 879
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+++V A A+G G EE +P D+ + I W +S G++ G
Sbjct: 880 ALSVTALYASGAGDALFGEGTTLEE--RGSPQDLVTKDITDTSIGAYW---TSAPGMVRG 934
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATR--VV 474
Y + + D + G ++ L + P ++ V A+ GEGE
Sbjct: 935 YRVSWKSLYDDVDTG--EKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDAT 992
Query: 475 TVLPSDSVPARITSFSRNIV-TPWK 498
T L DS ++ + N + WK
Sbjct: 993 TELSQDSKTLKVDEETENTMRVTWK 1017
Score = 59.7 bits (138), Expect = 6e-08
Identities = 77/291 (26%), Positives = 120/291 (41%), Gaps = 40/291 (13%)
Query: 72 MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSAS 131
+ +N++V + ++ + W P G P++ Y V Y + PS + ++VPG+
Sbjct: 1936 LARNVQVYNPTPNSLDVRW-DPAPG--PVLQYRVVYSPVDGTRPS--ESIVVPGNTRMVH 1990
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
++ L P T Y + ++A G+ PS P Q T +P P+++RV +++ L V W
Sbjct: 1991 LERLIPDTLYSVNLVALYSDGEGNPS-PAQGRT---LPRSGPRNLRVFGETTNSLSVAW- 2045
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
D +G + Y + + + TV G YT TV G R+ L LQ
Sbjct: 2046 ----DHADGPVQQYRIIY-----SPTV----GDPIDEYT--TVPG---RRNNVILQPLQP 2087
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRG 311
Y + V A V LPP + + RVSW+P P
Sbjct: 2088 DTPYKITVIAVYEDGDGGHLTGNG----RTVGLLPPQNIHISDEWYTRFRVSWDPSP--- 2140
Query: 312 RNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
+ +L GY++ Y PV E V + S TL L T Y V V A
Sbjct: 2141 -SPVL-GYKIVYKPVGSNEPMEAFVGEMTS---YTLHNLNPSTTYDVNVYA 2186
Score = 57.2 bits (132), Expect = 3e-07
Identities = 85/368 (23%), Positives = 152/368 (41%), Gaps = 57/368 (15%)
Query: 75 NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
++ + D T+ + W QP G + YI+ YK ++ P+ P++V + +V + +
Sbjct: 1479 SLNIYDVGPTTMHVQW-QPVGGAT---GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 1534
Query: 135 LQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQ 194
L P T Y + + A SEP +VT +P PQD+++ + + + V WEP
Sbjct: 1535 LVPNTEYAVTVQAVLHDLTSEPVTVREVT----LPLPRPQDLKLRDVTHSTMNVFWEPVP 1590
Query: 195 RDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAA 254
G + Y V ++ + V+ VE + + T+L L
Sbjct: 1591 -----GKVRKYIVRYKTPEED---------------VKEVE-VDRSETSTSLKDLFSQTL 1629
Query: 255 YAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNG 314
Y V V A + VP+ P L+ ++S+ R +W+ G +
Sbjct: 1630 YTVSVSAVHDEGESPPVTAQETT--RPVPA--PTNLKITEVTSEGFRGTWD----HGASD 1681
Query: 315 ILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTVCAF---TAAGDG 369
+ YR+T+AP +G+ D + ++G TL L T Y V++ A + D
Sbjct: 1682 V-SLYRITWAP----FGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDD 1736
Query: 370 V----RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ R P+ T + S P +++ ++ N + V W P S G + Y + Y
Sbjct: 1737 LIGSERTLPIL--TTQAPKSGPRNLQVYNATSNSLTVKWDPAS---GRVQKYRITYQPST 1791
Query: 425 EDGREEGT 432
+G E+ T
Sbjct: 1792 GEGNEQTT 1799
Score = 56.4 bits (130), Expect = 5e-07
Identities = 74/303 (24%), Positives = 120/303 (39%), Gaps = 41/303 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++++ D T+ + W +P G + YIV+YK E ++V V S TS S+
Sbjct: 1569 PQDLKLRDVTHSTMNVFW-EPVPGK--VRKYIVRYKTPEED----VKEVEVDRSETSTSL 1621
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
++L T Y + + A + G+S P + TT VP+ P ++++ +S TW+
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQE--TTRPVPA--PTNLKITEVTSEGFRGTWDH 1677
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
D+ S I P G+S + T+ + L +
Sbjct: 1678 GASDV------------------SLYRITWAPFGSSDKMETILNGD--ENTLVFENLNPN 1717
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXME----DVPSLPPGALQCNALSSQSVRVSWEPPP 308
Y V + A + P P LQ +S S+ V W+P
Sbjct: 1718 TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA- 1776
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+G +Q YR+TY P T GNE T L L+ T Y++TV + G+
Sbjct: 1777 ----SGRVQKYRITYQPSTG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 369 GVR 371
G R
Sbjct: 1832 GGR 1834
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/147 (25%), Positives = 72/147 (48%), Gaps = 14/147 (9%)
Query: 63 GSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
G + ++ + K ++V ++ T++++W +P G ++NY V Y+ +
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK--VVNYRVVYRPHGRGKQMVAK--- 1042
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
VP +VTS ++ LQP T+Y + ++ ++G+ + Q TT S P++++ +
Sbjct: 1043 VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQG-SGTTASRFKS--PRNLKTSDPT 1099
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGF 209
+ VTWEP G + GY V F
Sbjct: 1100 MSSFRVTWEPAP-----GEVKGYKVTF 1121
Score = 46.4 bits (105), Expect = 6e-04
Identities = 78/342 (22%), Positives = 133/342 (38%), Gaps = 45/342 (13%)
Query: 65 LSHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV 123
L+ Q P+ P+N++V + S ++ + W P +G + Y + Y+ P + Q +
Sbjct: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGR--VQKYRITYQ--PSTGEGNEQTTTI 1801
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
G S +Q L+P T Y I + E + T+ P +++RV S+
Sbjct: 1802 GGRQNSVVLQKLKPDTPY--TITVSSLYPDGEGGRMTGRGKTK--PLNTVRNLRVYDPST 1857
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
+ L V W+ + GN Y + + L+ PG +Y +
Sbjct: 1858 STLNVRWDHAE-----GNPRQYKLFYAPAAGGPEELVPI-PGNTNYAI------------ 1899
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVS 303
L LQ +Y V V + M + +Q + S+ V
Sbjct: 1900 --LRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR----NVQVYNPTPNSLDVR 1953
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W+P P +LQ YRV Y+PV +E V + + L L T YSV + A
Sbjct: 1954 WDPAP----GPVLQ-YRVVYSPVDGTRPSESIVVPGNTRM-VHLERLIPDTLYSVNLVAL 2007
Query: 364 TAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSW 404
+ G+G +P T +P S P +++ + N + V+W
Sbjct: 2008 YSDGEG-NPSPAQGRT---LPRSGPRNLRVFGETTNSLSVAW 2045
Score = 45.2 bits (102), Expect = 0.001
Identities = 66/296 (22%), Positives = 110/296 (37%), Gaps = 38/296 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++ D +I WT + + Y V +K + T +K + P +
Sbjct: 908 PQDLVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDD-VDTGEKNL-PEDAIHTMI 962
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP T Y + + A G+ EP + T E+ S + ++V+ ++ + VTW+P
Sbjct: 963 ENLQPETKYRISVFATYSSGEGEP---LTGDATTEL-SQDSKTLKVDEETENTMRVTWKP 1018
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G ++ Y V ++ + ++A P + TV L LQ
Sbjct: 1019 AP-----GKVVNYRVVYRP-HGRGKQMVAKVPPTVTSTV--------------LKRLQPQ 1058
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y + V P L+ + + S RV+WEP P
Sbjct: 1059 TTYDITVLPIYKMGEGKLRQGSGTTASR---FKSPRNLKTSDPTMSSFRVTWEPAP---- 1111
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
G ++GY+VT+ P D + V L LR T Y V V G+
Sbjct: 1112 -GEVKGYKVTFHPTGDDRRLGELVVGPYDNT-VVLEELRAGTTYKVNVFGMFDGGE 1165
Score = 45.2 bits (102), Expect = 0.001
Identities = 131/597 (21%), Positives = 226/597 (37%), Gaps = 74/597 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
E P N+ + ++ R+ ++SWT P + + Y V+Y P S Q+ V TS
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPP---SDSVDRYKVEY--YPVS-GGKRQEFYVSRMETST 1439
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+++L+P T Y + + + + + E S+P++ TE+ P + + T + V W
Sbjct: 1440 VLKDLKPETEYVVNVYS---VVEDEYSEPLK--GTEKTLPVPVVSLNIYDVGPTTMHVQW 1494
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+P G GY + ++ + VR G + L+ L
Sbjct: 1495 QPV------GGATGYILSYKPVKDTEPT--------RPKEVR----LGPTVNDMQLTDLV 1536
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
+ YAV VQA +P P L+ ++ ++ V WEP P +
Sbjct: 1537 PNTEYAVTVQA----VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK 1592
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
R I++ Y+ V + V S T+L L T Y+V+V A G+
Sbjct: 1593 VRKYIVR-YKTPEEDVKE-------VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE-- 1642
Query: 371 RAAPVYC-HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL------VGYTLYMSV 423
+ PV T VP AP ++K + +W +S + G + M
Sbjct: 1643 -SPPVTAQETTRPVP-APTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
I +G E L+P+T+ +E S + A + + +G ++T S P
Sbjct: 1701 ILNGDENTLVFENLNPNTI-YEVSIT---AIYPDESESDDLIGSERTLPILTTQAPKSGP 1756
Query: 484 ARITSF---SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
+ + S ++ W + S K + +T G G E T + +
Sbjct: 1757 RNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPST----GEGNEQT--TTIGGRQNSVV 1809
Query: 541 SMTQSADSGNYTCSVENIHGRDE-VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQG 597
D+ YT +V +++ E T K P + L V D +L+++W D
Sbjct: 1810 LQKLKPDT-PYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW-DHA 1867
Query: 598 DGGSPILGYVINYKREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
+G Y + Y G EEL + T+ +L NL T Y + + G G
Sbjct: 1868 EGNP--RQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDG 1922
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+NI + D+ ++SW SP++ Y + YK + P + V G +TS ++
Sbjct: 2119 PQNIHISDEWYTRFRVSWDP---SPSPVLGYKIVYKPVGSN---EPMEAFV-GEMTSYTL 2171
Query: 133 QNLQPATSYHLRIIAENRLGQSEP 156
NL P+T+Y + + A+ G S P
Sbjct: 2172 HNLNPSTTYDVNVYAQYDSGLSVP 2195
Score = 43.6 bits (98), Expect = 0.004
Identities = 81/380 (21%), Positives = 142/380 (37%), Gaps = 35/380 (9%)
Query: 285 LPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLH 344
+PP L + ++S + +W P G N + Y +TY +E V + S
Sbjct: 633 VPPKDLSFSEVTSYGFKTNWSPA---GEN--VFSYHITYKEAAG--DDEVTVVEPASSTS 685
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
LS L+ T Y V V A G + A T E+V AP ++K + + ++W
Sbjct: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGE--ETTEEVKGAPRNLKVTDETTDSFKITW 743
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
+P VL +Y V G + + +P T + T ++ VS
Sbjct: 744 --TQAPGRVLRYRIIYRPV-----AGGESREVTTPPNQRRRTLENLIPDT-KYEVSVIPE 795
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G T + ++ V R + P + LS + G P + + +
Sbjct: 796 YFSGPGTPLTGNAATEEV--RGNPRDLRVSDPTTSTMKLSWS--GAPGKVKQYLVTYTPV 851
Query: 525 ESTLRKNVSSDGTLTISMTQSADSG-NYTCSVENIH--GRDEVTY----TVEVKVPPQPP 577
+ V+ G T ++ Q G Y SV ++ G + + T+E + PQ
Sbjct: 852 AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD- 910
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE--ELQVEAGTSEHVLPNLW 635
L D S+ W+ + GY +++K + D + E + ++ NL
Sbjct: 911 -LVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQ 966
Query: 636 CGTRYQLYITAFNRIGTGLP 655
T+Y++ + A G G P
Sbjct: 967 PETKYRISVFATYSSGEGEP 986
Score = 41.1 bits (92), Expect = 0.021
Identities = 81/347 (23%), Positives = 135/347 (38%), Gaps = 47/347 (13%)
Query: 74 KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI-VPGSVTSASV 132
+N+RV D + T+ + W +A +P QYK P++++ +PG+ A +
Sbjct: 1848 RNLRVYDPSTSTLNVRWD--HAEGNPR-----QYKLFYAPAAGGPEELVPIPGNTNYAIL 1900
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP TSY + ++ G + T + G ++V+V + L V W+P
Sbjct: 1901 RNLQPDTSYTVTVVPVYTEGDGGRTS----DTGRTLMRGLARNVQVYNPTPNSLDVRWDP 1956
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G +L Y V + ++ PG R V L L
Sbjct: 1957 AP-----GPVLQYRVVYSPVDGTRPSESIVVPG----NTRMVH----------LERLIPD 1997
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y+V + A S +P P L+ ++ S+ V+W+
Sbjct: 1998 TLYSVNLVALYSDGEGNPSPAQG----RTLPRSGPRNLRVFGETTNSLSVAWD-----HA 2048
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
+G +Q YR+ Y+P T ++ T + L L+ T Y +TV A GDG
Sbjct: 2049 DGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHL 2107
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
T +P P +I + + VSW P SP ++GY +
Sbjct: 2108 TG-NGRTVGLLP--PQNIHISDEWYTRFRVSWDPSPSP---VLGYKI 2148
Score = 39.9 bits (89), Expect = 0.049
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 567 TVEVKV-PPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWEELQVEA 624
++E +V PP ++D +++H+ W+ D PI+GY I G +E + A
Sbjct: 20 SIEAEVDPPSDLNFKIIDE--NTVHMSWAKPVD---PIVGYRITVDPTTDGPTKEFTLSA 74
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
T+E +L L T Y + IT+++ + +P + T PV+ K + +
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGK-TEIQKC 133
Query: 683 TVTVWLD 689
+V+ W D
Sbjct: 134 SVSAWTD 140
Score = 38.3 bits (85), Expect = 0.15
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 58 VDLRIGSL--SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VD ++G L +V E P N+ ++ S+ ++++W SP+ Y V P +
Sbjct: 320 VDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP---SPSPVTGYKVIL--TPMTAG 374
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
S + V T+ SV++L T Y + + A + SEP ++ T +V +
Sbjct: 375 SRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRG 434
Query: 176 VRVEA 180
V ++A
Sbjct: 435 VDIKA 439
Score = 37.5 bits (83), Expect = 0.26
Identities = 46/224 (20%), Positives = 86/224 (38%), Gaps = 15/224 (6%)
Query: 525 ESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENI-HGRDEVTYTV-EVKVP-PQPPILA 580
E T K V T+ + +T + Y +V+ + H TV EV +P P+P L
Sbjct: 1514 EPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLK 1573
Query: 581 VVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRY 640
+ D ++++ W + Y++ YK D +E++V+ + L +L+ T Y
Sbjct: 1574 LRDVTHSTMNVFWEPVP---GKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLY 1630
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ ++A + G P + T VP + + T + +W G +
Sbjct: 1631 TVSVSAVHDEGESPP--VTAQETTRPVPAPTN----LKITEVTSEGFRGTWDHGASDVSL 1684
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I + + + E L P Y++ ITA
Sbjct: 1685 YRITWAPFGSSD--KMETILNGDENTLVFENLNPNTIYEVSITA 1726
>AL080250-2|CAI19898.1| 3063|Homo sapiens collagen type XII alpha 1
protein.
Length = 3063
Score = 81.0 bits (191), Expect = 2e-14
Identities = 95/409 (23%), Positives = 174/409 (42%), Gaps = 57/409 (13%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
+ +V P+N++V D+ + + +I+WTQ ++ Y + Y+ ++V P
Sbjct: 719 TEEVKGAPRNLKVTDETTDSFKITWTQ---APGRVLRYRIIYRPVA---GGESREVTTPP 772
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
+ +++NL P T Y + +I E G P P+ E G P+D+RV +++
Sbjct: 773 NQRRRTLENLIPDTKYEVSVIPEYFSG---PGTPLTGNAATEEVRGNPRDLRVSDPTTST 829
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
+ ++W G + Y V + + GG + V TV G T T
Sbjct: 830 MKLSWSGAP-----GKVKQYLVTYTPV-----------AGGETQEV-TVRGDTT---NTV 869
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L GL++ YA+ V A + +E+ S P L ++ S+ W
Sbjct: 870 LQGLKEGTQYALSVTALYA-SGAGDALFGEGTTLEERGS--PQDLVTKDITDTSIGAYWT 926
Query: 306 PPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHTTLSGLRRYTNYSVTVCAF 363
P G+++GYRV++ + Y + D K + +HT + L+ T Y ++V A
Sbjct: 927 SAP-----GMVRGYRVSWKSL---YDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFAT 978
Query: 364 TAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSV 423
++G+G P+ ++ +K + N + V+W P +P G +V Y +
Sbjct: 979 YSSGEG---EPLTGDATTELSQDSKTLKVDEETENTMRVTWKP--AP-GKVVNYRVVY-- 1030
Query: 424 IEDGREEGTHKRMLS---PSTLSHETSRSPPRATHQFWVSASTRLGEGE 469
R G K+M++ P+ S R P+ T+ V ++GEG+
Sbjct: 1031 ----RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK 1075
Score = 76.6 bits (180), Expect = 5e-13
Identities = 108/445 (24%), Positives = 183/445 (41%), Gaps = 51/445 (11%)
Query: 58 VDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPST 117
++ + ++ + PK++ + S + +W+ AG + + +Y + YKEA T
Sbjct: 620 IEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSP--AGEN-VFSYHITYKEAAGDDEVT 676
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
V+ P S TS + +L+P T Y + + AE G S P + TTEEV G P++++
Sbjct: 677 ---VVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEE--TTEEV-KGAPRNLK 730
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
V +++ +TW G +L Y + ++ + GG S V T
Sbjct: 731 VTDETTDSFKITWTQAP-----GRVLRYRIIYRPV-----------AGGESREVTTPPN- 773
Query: 238 GTARSRTTLSGLQKHAAYAV-VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
+ R TL L Y V V+ Y S E+V P L+ + +
Sbjct: 774 ---QRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAAT---EEVRGNPRD-LRVSDPT 826
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+ ++++SW P G ++ Y VTY PV G VT + +T L GL+ T Y
Sbjct: 827 TSTMKLSWSGAP-----GKVKQYLVTYTPVAG--GETQEVTVRGDTTNTVLQGLKEGTQY 879
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+++V A A+G G EE +P D+ + I W +S G++ G
Sbjct: 880 ALSVTALYASGAGDALFGEGTTLEE--RGSPQDLVTKDITDTSIGAYW---TSAPGMVRG 934
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATR--VV 474
Y + + D + G ++ L + P ++ V A+ GEGE
Sbjct: 935 YRVSWKSLYDDVDTG--EKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDAT 992
Query: 475 TVLPSDSVPARITSFSRNIV-TPWK 498
T L DS ++ + N + WK
Sbjct: 993 TELSQDSKTLKVDEETENTMRVTWK 1017
Score = 59.7 bits (138), Expect = 6e-08
Identities = 77/291 (26%), Positives = 120/291 (41%), Gaps = 40/291 (13%)
Query: 72 MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSAS 131
+ +N++V + ++ + W P G P++ Y V Y + PS + ++VPG+
Sbjct: 1936 LARNVQVYNPTPNSLDVRW-DPAPG--PVLQYRVVYSPVDGTRPS--ESIVVPGNTRMVH 1990
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
++ L P T Y + ++A G+ PS P Q T +P P+++RV +++ L V W
Sbjct: 1991 LERLIPDTLYSVNLVALYSDGEGNPS-PAQGRT---LPRSGPRNLRVFGETTNSLSVAW- 2045
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
D +G + Y + + + TV G YT TV G R+ L LQ
Sbjct: 2046 ----DHADGPVQQYRIIY-----SPTV----GDPIDEYT--TVPG---RRNNVILQPLQP 2087
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRG 311
Y + V A V LPP + + RVSW+P P
Sbjct: 2088 DTPYKITVIAVYEDGDGGHLTGNG----RTVGLLPPQNIHISDEWYTRFRVSWDPSP--- 2140
Query: 312 RNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
+ +L GY++ Y PV E V + S TL L T Y V V A
Sbjct: 2141 -SPVL-GYKIVYKPVGSNEPMEAFVGEMTS---YTLHNLNPSTTYDVNVYA 2186
Score = 57.2 bits (132), Expect = 3e-07
Identities = 85/368 (23%), Positives = 152/368 (41%), Gaps = 57/368 (15%)
Query: 75 NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
++ + D T+ + W QP G + YI+ YK ++ P+ P++V + +V + +
Sbjct: 1479 SLNIYDVGPTTMHVQW-QPVGGAT---GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 1534
Query: 135 LQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQ 194
L P T Y + + A SEP +VT +P PQD+++ + + + V WEP
Sbjct: 1535 LVPNTEYAVTVQAVLHDLTSEPVTVREVT----LPLPRPQDLKLRDVTHSTMNVFWEPVP 1590
Query: 195 RDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAA 254
G + Y V ++ + V+ VE + + T+L L
Sbjct: 1591 -----GKVRKYIVRYKTPEED---------------VKEVE-VDRSETSTSLKDLFSQTL 1629
Query: 255 YAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNG 314
Y V V A + VP+ P L+ ++S+ R +W+ G +
Sbjct: 1630 YTVSVSAVHDEGESPPVTAQETT--RPVPA--PTNLKITEVTSEGFRGTWD----HGASD 1681
Query: 315 ILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTVCAF---TAAGDG 369
+ YR+T+AP +G+ D + ++G TL L T Y V++ A + D
Sbjct: 1682 V-SLYRITWAP----FGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDD 1736
Query: 370 V----RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ R P+ T + S P +++ ++ N + V W P S G + Y + Y
Sbjct: 1737 LIGSERTLPIL--TTQAPKSGPRNLQVYNATSNSLTVKWDPAS---GRVQKYRITYQPST 1791
Query: 425 EDGREEGT 432
+G E+ T
Sbjct: 1792 GEGNEQTT 1799
Score = 56.4 bits (130), Expect = 5e-07
Identities = 74/303 (24%), Positives = 120/303 (39%), Gaps = 41/303 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++++ D T+ + W +P G + YIV+YK E ++V V S TS S+
Sbjct: 1569 PQDLKLRDVTHSTMNVFW-EPVPGK--VRKYIVRYKTPEED----VKEVEVDRSETSTSL 1621
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
++L T Y + + A + G+S P + TT VP+ P ++++ +S TW+
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQE--TTRPVPA--PTNLKITEVTSEGFRGTWDH 1677
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
D+ S I P G+S + T+ + L +
Sbjct: 1678 GASDV------------------SLYRITWAPFGSSDKMETILNGD--ENTLVFENLNPN 1717
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXME----DVPSLPPGALQCNALSSQSVRVSWEPPP 308
Y V + A + P P LQ +S S+ V W+P
Sbjct: 1718 TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA- 1776
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+G +Q YR+TY P T GNE T L L+ T Y++TV + G+
Sbjct: 1777 ----SGRVQKYRITYQPSTG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 369 GVR 371
G R
Sbjct: 1832 GGR 1834
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/147 (25%), Positives = 72/147 (48%), Gaps = 14/147 (9%)
Query: 63 GSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
G + ++ + K ++V ++ T++++W +P G ++NY V Y+ +
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK--VVNYRVVYRPHGRGKQMVAK--- 1042
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
VP +VTS ++ LQP T+Y + ++ ++G+ + Q TT S P++++ +
Sbjct: 1043 VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQG-SGTTASRFKS--PRNLKTSDPT 1099
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGF 209
+ VTWEP G + GY V F
Sbjct: 1100 MSSFRVTWEPAP-----GEVKGYKVTF 1121
Score = 46.4 bits (105), Expect = 6e-04
Identities = 78/342 (22%), Positives = 133/342 (38%), Gaps = 45/342 (13%)
Query: 65 LSHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV 123
L+ Q P+ P+N++V + S ++ + W P +G + Y + Y+ P + Q +
Sbjct: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGR--VQKYRITYQ--PSTGEGNEQTTTI 1801
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
G S +Q L+P T Y I + E + T+ P +++RV S+
Sbjct: 1802 GGRQNSVVLQKLKPDTPY--TITVSSLYPDGEGGRMTGRGKTK--PLNTVRNLRVYDPST 1857
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
+ L V W+ + GN Y + + L+ PG +Y +
Sbjct: 1858 STLNVRWDHAE-----GNPRQYKLFYAPAAGGPEELVPI-PGNTNYAI------------ 1899
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVS 303
L LQ +Y V V + M + +Q + S+ V
Sbjct: 1900 --LRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR----NVQVYNPTPNSLDVR 1953
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W+P P +LQ YRV Y+PV +E V + + L L T YSV + A
Sbjct: 1954 WDPAP----GPVLQ-YRVVYSPVDGTRPSESIVVPGNTRM-VHLERLIPDTLYSVNLVAL 2007
Query: 364 TAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSW 404
+ G+G +P T +P S P +++ + N + V+W
Sbjct: 2008 YSDGEG-NPSPAQGRT---LPRSGPRNLRVFGETTNSLSVAW 2045
Score = 45.2 bits (102), Expect = 0.001
Identities = 66/296 (22%), Positives = 110/296 (37%), Gaps = 38/296 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++ D +I WT + + Y V +K + T +K + P +
Sbjct: 908 PQDLVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDD-VDTGEKNL-PEDAIHTMI 962
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP T Y + + A G+ EP + T E+ S + ++V+ ++ + VTW+P
Sbjct: 963 ENLQPETKYRISVFATYSSGEGEP---LTGDATTEL-SQDSKTLKVDEETENTMRVTWKP 1018
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G ++ Y V ++ + ++A P + TV L LQ
Sbjct: 1019 AP-----GKVVNYRVVYRP-HGRGKQMVAKVPPTVTSTV--------------LKRLQPQ 1058
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y + V P L+ + + S RV+WEP P
Sbjct: 1059 TTYDITVLPIYKMGEGKLRQGSGTTASR---FKSPRNLKTSDPTMSSFRVTWEPAP---- 1111
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
G ++GY+VT+ P D + V L LR T Y V V G+
Sbjct: 1112 -GEVKGYKVTFHPTGDDRRLGELVVGPYDNT-VVLEELRAGTTYKVNVFGMFDGGE 1165
Score = 45.2 bits (102), Expect = 0.001
Identities = 131/597 (21%), Positives = 226/597 (37%), Gaps = 74/597 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
E P N+ + ++ R+ ++SWT P + + Y V+Y P S Q+ V TS
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPP---SDSVDRYKVEY--YPVS-GGKRQEFYVSRMETST 1439
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+++L+P T Y + + + + + E S+P++ TE+ P + + T + V W
Sbjct: 1440 VLKDLKPETEYVVNVYS---VVEDEYSEPLK--GTEKTLPVPVVSLNIYDVGPTTMHVQW 1494
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+P G GY + ++ + VR G + L+ L
Sbjct: 1495 QPV------GGATGYILSYKPVKDTEPT--------RPKEVR----LGPTVNDMQLTDLV 1536
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
+ YAV VQA +P P L+ ++ ++ V WEP P +
Sbjct: 1537 PNTEYAVTVQA----VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK 1592
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
R I++ Y+ V + V S T+L L T Y+V+V A G+
Sbjct: 1593 VRKYIVR-YKTPEEDVKE-------VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE-- 1642
Query: 371 RAAPVYC-HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL------VGYTLYMSV 423
+ PV T VP AP ++K + +W +S + G + M
Sbjct: 1643 -SPPVTAQETTRPVP-APTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
I +G E L+P+T+ +E S + A + + +G ++T S P
Sbjct: 1701 ILNGDENTLVFENLNPNTI-YEVSIT---AIYPDESESDDLIGSERTLPILTTQAPKSGP 1756
Query: 484 ARITSF---SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
+ + S ++ W + S K + +T G G E T + +
Sbjct: 1757 RNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPST----GEGNEQT--TTIGGRQNSVV 1809
Query: 541 SMTQSADSGNYTCSVENIHGRDE-VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQG 597
D+ YT +V +++ E T K P + L V D +L+++W D
Sbjct: 1810 LQKLKPDT-PYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW-DHA 1867
Query: 598 DGGSPILGYVINYKREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
+G Y + Y G EEL + T+ +L NL T Y + + G G
Sbjct: 1868 EGNP--RQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDG 1922
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+NI + D+ ++SW SP++ Y + YK + P + V G +TS ++
Sbjct: 2119 PQNIHISDEWYTRFRVSWDP---SPSPVLGYKIVYKPVGSN---EPMEAFV-GEMTSYTL 2171
Query: 133 QNLQPATSYHLRIIAENRLGQSEP 156
NL P+T+Y + + A+ G S P
Sbjct: 2172 HNLNPSTTYDVNVYAQYDSGLSVP 2195
Score = 43.6 bits (98), Expect = 0.004
Identities = 81/380 (21%), Positives = 142/380 (37%), Gaps = 35/380 (9%)
Query: 285 LPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLH 344
+PP L + ++S + +W P G N + Y +TY +E V + S
Sbjct: 633 VPPKDLSFSEVTSYGFKTNWSPA---GEN--VFSYHITYKEAAG--DDEVTVVEPASSTS 685
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
LS L+ T Y V V A G + A T E+V AP ++K + + ++W
Sbjct: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGE--ETTEEVKGAPRNLKVTDETTDSFKITW 743
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
+P VL +Y V G + + +P T + T ++ VS
Sbjct: 744 --TQAPGRVLRYRIIYRPV-----AGGESREVTTPPNQRRRTLENLIPDT-KYEVSVIPE 795
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G T + ++ V R + P + LS + G P + + +
Sbjct: 796 YFSGPGTPLTGNAATEEV--RGNPRDLRVSDPTTSTMKLSWS--GAPGKVKQYLVTYTPV 851
Query: 525 ESTLRKNVSSDGTLTISMTQSADSG-NYTCSVENIH--GRDEVTY----TVEVKVPPQPP 577
+ V+ G T ++ Q G Y SV ++ G + + T+E + PQ
Sbjct: 852 AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD- 910
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE--ELQVEAGTSEHVLPNLW 635
L D S+ W+ + GY +++K + D + E + ++ NL
Sbjct: 911 -LVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQ 966
Query: 636 CGTRYQLYITAFNRIGTGLP 655
T+Y++ + A G G P
Sbjct: 967 PETKYRISVFATYSSGEGEP 986
Score = 41.1 bits (92), Expect = 0.021
Identities = 81/347 (23%), Positives = 135/347 (38%), Gaps = 47/347 (13%)
Query: 74 KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI-VPGSVTSASV 132
+N+RV D + T+ + W +A +P QYK P++++ +PG+ A +
Sbjct: 1848 RNLRVYDPSTSTLNVRWD--HAEGNPR-----QYKLFYAPAAGGPEELVPIPGNTNYAIL 1900
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP TSY + ++ G + T + G ++V+V + L V W+P
Sbjct: 1901 RNLQPDTSYTVTVVPVYTEGDGGRTS----DTGRTLMRGLARNVQVYNPTPNSLDVRWDP 1956
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G +L Y V + ++ PG R V L L
Sbjct: 1957 AP-----GPVLQYRVVYSPVDGTRPSESIVVPG----NTRMVH----------LERLIPD 1997
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y+V + A S +P P L+ ++ S+ V+W+
Sbjct: 1998 TLYSVNLVALYSDGEGNPSPAQG----RTLPRSGPRNLRVFGETTNSLSVAWD-----HA 2048
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
+G +Q YR+ Y+P T ++ T + L L+ T Y +TV A GDG
Sbjct: 2049 DGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHL 2107
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
T +P P +I + + VSW P SP ++GY +
Sbjct: 2108 TG-NGRTVGLLP--PQNIHISDEWYTRFRVSWDPSPSP---VLGYKI 2148
Score = 39.9 bits (89), Expect = 0.049
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 567 TVEVKV-PPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWEELQVEA 624
++E +V PP ++D +++H+ W+ D PI+GY I G +E + A
Sbjct: 20 SIEAEVDPPSDLNFKIIDE--NTVHMSWAKPVD---PIVGYRITVDPTTDGPTKEFTLSA 74
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
T+E +L L T Y + IT+++ + +P + T PV+ K + +
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGK-TEIQKC 133
Query: 683 TVTVWLD 689
+V+ W D
Sbjct: 134 SVSAWTD 140
Score = 38.3 bits (85), Expect = 0.15
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 58 VDLRIGSL--SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VD ++G L +V E P N+ ++ S+ ++++W SP+ Y V P +
Sbjct: 320 VDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP---SPSPVTGYKVIL--TPMTAG 374
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
S + V T+ SV++L T Y + + A + SEP ++ T +V +
Sbjct: 375 SRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRG 434
Query: 176 VRVEA 180
V ++A
Sbjct: 435 VDIKA 439
Score = 37.5 bits (83), Expect = 0.26
Identities = 46/224 (20%), Positives = 86/224 (38%), Gaps = 15/224 (6%)
Query: 525 ESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENI-HGRDEVTYTV-EVKVP-PQPPILA 580
E T K V T+ + +T + Y +V+ + H TV EV +P P+P L
Sbjct: 1514 EPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLK 1573
Query: 581 VVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRY 640
+ D ++++ W + Y++ YK D +E++V+ + L +L+ T Y
Sbjct: 1574 LRDVTHSTMNVFWEPVP---GKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLY 1630
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ ++A + G P + T VP + + T + +W G +
Sbjct: 1631 TVSVSAVHDEGESPP--VTAQETTRPVPAPTN----LKITEVTSEGFRGTWDHGASDVSL 1684
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I + + + E L P Y++ ITA
Sbjct: 1685 YRITWAPFGSSD--KMETILNGDENTLVFENLNPNTIYEVSITA 1726
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 80.6 bits (190), Expect = 3e-14
Identities = 79/335 (23%), Positives = 138/335 (41%), Gaps = 26/335 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQ-YKEAP-ESWPSTPQKVIVPGS 126
+P P V D T+ +SW + +YI++ + A SW + + V
Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV----K 579
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
+++++ L+P Y + A N G S+PSQ T++V P+ D + +
Sbjct: 580 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN 639
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR---TVEGAGTARS 242
++ P L + +I ++ Q+ I P GA++ E A++
Sbjct: 640 AVLHLHNPTV-LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN 698
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC--NALSSQSV 300
+ L+K Y + + + + +E+ PS PP + N + ++
Sbjct: 699 SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAI 758
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDA--VTKQISG--LHTTLSGLRRYTN 355
VSW+PPP +NG++Q Y+V W GNE + K + G L + L
Sbjct: 759 LVSWQPPPEDTQNGMVQEYKV-------WCLGNETRYHINKTVDGSTLSVVIPFLVPGIR 811
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAPAD 389
YSV V A T AG GV++ P + + P +P D
Sbjct: 812 YSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPED 846
Score = 52.8 bits (121), Expect = 7e-06
Identities = 75/317 (23%), Positives = 115/317 (36%), Gaps = 32/317 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G+ EA+ +TV P + R+ V ++ C G P PA W
Sbjct: 293 AENMVGKAEASATLTVQVGSEPPHFVVK-PRDQVVALGRTVTFQCEATGNPQPAIFWRRE 351
Query: 521 GVGL--------ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD------EVTY 566
G +S+ R +VS G LTI+ Q +D G Y C N+ G EVT
Sbjct: 352 GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVE 623
+ + PP Q P+ V + + L G IL D Q+E
Sbjct: 412 VIADRPPPVIRQGPVNQTV-AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGT----------GLPCDIVHAYTKGTVPVKPKH 673
G + L RY + + T G+P +P P
Sbjct: 471 NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
++ ++ TVT+ W + G Y + + S W+ V+ +V+ TE ++ GL
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK-TE-TSAIKGL 588
Query: 733 TPAAHYQLRITAHNNAG 749
P A Y + A N G
Sbjct: 589 KPNAIYLFLVRAANAYG 605
Score = 52.4 bits (120), Expect = 9e-06
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY 551
N+ ++ C G P P W + L + R + D TL I + D G+Y
Sbjct: 231 NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSY 289
Query: 552 TCSVENIHGRDEVTYTVEVKVPPQPPILAV 581
TC EN+ G+ E + T+ V+V +PP V
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVV 319
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
G P P +W +G L+ + G L I+ T+ +D+G Y C N+ G E +
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERE-SEVA 215
Query: 569 EVKVPPQP 576
E+ V +P
Sbjct: 216 ELTVLERP 223
>AY358146-1|AAQ88513.1| 847|Homo sapiens YVTM2421 protein.
Length = 847
Score = 80.2 bits (189), Expect = 4e-14
Identities = 161/718 (22%), Positives = 265/718 (36%), Gaps = 75/718 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
PE P ++ + ++ + W P S I NY++++ E ++ + GS
Sbjct: 22 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKR---NSGFRQCFFGSQKH 78
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA Y R+ A N +G S SQ V T +P P +R+ T + +
Sbjct: 79 CKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQ-MPSALRLVRAGITWVTLQ 137
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P+ ++ Y + QE + N + YT + T+ L
Sbjct: 138 WSKPE-GCSPEEVITYTLEIQE-DENDNLF------HPKYTGEDL--------TCTVKNL 181
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A N+ D P P L ++S V W+PP
Sbjct: 182 KRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKD 241
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTVCAFTA 365
G + IL+ Y + +TD GN +A ++ SG T T + L+ T Y + C +
Sbjct: 242 NGGSEILK-YLL---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCIST 295
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YTLYMSV 423
G + + T P + ++K + + W P+S +G V Y++ M+
Sbjct: 296 GGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE 355
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
ED E H P L P ++F V A G G + V + + P
Sbjct: 356 PEDVASEVYH----GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPP 410
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSSDGTLT 539
+ + P C VG +P ++ ++ L E + GT T
Sbjct: 411 GQCKA-------PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDT 463
Query: 540 -ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAV-----VDSYAD 587
+ + Y C ++ N G + V + P P L V +D+Y D
Sbjct: 464 RFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPD 523
Query: 588 S----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLY 643
S L L W + + GS IL Y I+ GD + V T+ HV+ +L T Y++
Sbjct: 524 SPSACLVLNWEEPCNNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPETTYRIR 577
Query: 644 ITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
I A N IG G + A T+ P+ P+ + W DS + ++
Sbjct: 578 IQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHAAEDIV 635
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
++ R +S + + V LT Y RI A + AG Y F+T
Sbjct: 636 YTLQLEDRNKRFIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFST 692
Score = 62.5 bits (145), Expect = 8e-09
Identities = 45/165 (27%), Positives = 80/165 (48%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP +R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 117 IPQMPSALRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 172
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 173 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 232
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 233 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 276
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 8/192 (4%)
Query: 562 DEVTYTVEVKVP--PQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEE 619
+ V++T P P PP LA SL LQW D GS I Y++ + +
Sbjct: 11 EPVSFTTHSCAPECPFPPKLA--HRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGF 68
Query: 620 LQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMIT 678
Q G+ +H L L Y + A N IGT V YT G +P P +++
Sbjct: 69 RQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSALRLVR 128
Query: 679 LNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAH 737
T VT+ W G ++ + +E +E L + +V L +
Sbjct: 129 AGITWVTLQWSKPEGCSPEEVITYTLEIQEDEND--NLFHPKYTGEDLTCTVKNLKRSTQ 186
Query: 738 YQLRITAHNNAG 749
Y+ R+TA N G
Sbjct: 187 YKFRLTASNTEG 198
Score = 34.7 bits (76), Expect = 1.8
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 600 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 659
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 660 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEVNSCEILWET 719
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 720 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 770
>AK223599-1|BAD97319.1| 1204|Homo sapiens factor for adipocyte
differentiation 104 variant protein.
Length = 1204
Score = 79.8 bits (188), Expect = 5e-14
Identities = 162/718 (22%), Positives = 264/718 (36%), Gaps = 75/718 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
PE P ++ + ++ + W P S I NY++++ E ++ + GS
Sbjct: 379 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKR---NSGFRQCFFGSQKH 435
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA Y R+ A N +G S SQ V T +P P V A T + +
Sbjct: 436 CKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQ 494
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P+ ++ Y + QE + N + YT + T+ L
Sbjct: 495 WSKPE-GCSPEEVITYTLEIQE-DENDNLF------HPKYTGEDL--------TCTVKNL 538
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A N+ D P P L ++S V W+PP
Sbjct: 539 KRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKD 598
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTVCAFTA 365
G + IL+ Y + +TD GN +A ++ SG T T + L+ T Y + C +
Sbjct: 599 NGGSEILK-YLL---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCIST 652
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YTLYMSV 423
G + + T P + ++K + + W P+S +G V Y++ M+
Sbjct: 653 GGHSQCSESLPVRTLSIAPGQCRSPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE 712
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
ED E H P L P ++F V A G G + V + + P
Sbjct: 713 PEDVASEVYH----GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPP 767
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSSDGTLT 539
+ + P C VG +P ++ ++ L E + GT T
Sbjct: 768 GQCKA-------PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDT 820
Query: 540 -ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAV-----VDSYAD 587
+ + Y C ++ N G + V + P P L V +D+Y D
Sbjct: 821 RFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPD 880
Query: 588 S----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLY 643
S L L W + + GS IL Y I+ GD + V T+ HV+ +L T Y++
Sbjct: 881 SPSACLVLNWEEPCNNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPETTYRIR 934
Query: 644 ITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
I A N IG G + A T+ P+ P+ + W DS + ++
Sbjct: 935 IQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHAAEDIV 992
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
++ R +S + + V LT Y RI A + AG Y F+T
Sbjct: 993 YTLQLEDRNKRFIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFST 1049
Score = 61.7 bits (143), Expect = 1e-08
Identities = 126/613 (20%), Positives = 218/613 (35%), Gaps = 55/613 (8%)
Query: 77 RVIDQQSRTIQISWTQPYA---GNSPIINYIVQYKEA-PESWPSTPQKVIVPGSVTSASV 132
+V + Q+R + +SW P G +++ Y+ A + K+I G ++
Sbjct: 283 QVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNL 342
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-PQDVRVEAKSSTELIVTWE 191
++L+PAT YH+R+ A + S+PV TT P P P + +KSS L + W+
Sbjct: 343 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSS--LTLQWK 400
Query: 192 PPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P + NG+ I Y + + E N SG + ++ L+ L
Sbjct: 401 AP---IDNGSKITNYLLEWDEGKRN------SGFRQCFF---------GSQKHCKLTKLC 442
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + A N + ++P +P A V + W P
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKP--- 498
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFTAAGD 368
G +TY N++ + +G L T+ L+R T Y + A G
Sbjct: 499 --EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGK 556
Query: 369 GVRAAPVYCHTEEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ + C T D P P +K V+S V W PP G + Y+ I D
Sbjct: 557 SCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHG-FSVKWDPPKDNGGSEI--LKYLLEITD 613
Query: 427 GREEGTHKRM-LSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR 485
G E + S S + + P ++ + G + + + V P +
Sbjct: 614 GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQ 673
Query: 486 ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG------TLT 539
S R + P + + L + VPA + ++ +E T ++V+S+ T
Sbjct: 674 CRS-PRVLGRPKHKEVHLEWD---VPASESGCEVSEYSVEMTEPEDVASEVYHGPELECT 729
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP---ILAVVDSYADSLHL-QWSD 595
+ + N G + E+ PP + D L W
Sbjct: 730 VGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWES 789
Query: 596 QGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
G+ I Y + + E + EL + + +L +Y + AFN+ G G
Sbjct: 790 PDSSGADISEYRLEW-GEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPY 848
Query: 656 CDIVHAYTKGTVP 668
++V T + P
Sbjct: 849 SELVLCQTPASAP 861
Score = 60.5 bits (140), Expect = 3e-08
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 474 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 529
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 530 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 589
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 590 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 633
Score = 58.0 bits (134), Expect = 2e-07
Identities = 72/295 (24%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK-VGVPAPAT-TWTMNGVGL 524
E E RV +L P +R +V W + LSC G+ P + ++ G
Sbjct: 266 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGR 325
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSV----ENIHGR--DEVTYTVEVKVP--PQP 576
+ K + S L ++ + +Y V ++ G + V++T P P P
Sbjct: 326 DGKY-KIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFP 384
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LPNLW 635
P LA SL LQW D GS I Y++ + + Q G+ +H L L
Sbjct: 385 PKLA--HRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLC 442
Query: 636 CGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDG 694
Y + A N IGT V YT G +P P +++ T VT+ W G
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCS 502
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + +E +E L + +V L + Y+ R+TA N G
Sbjct: 503 PEEVITYTLEIQEDEND--NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEG 555
Score = 42.7 bits (96), Expect = 0.007
Identities = 92/438 (21%), Positives = 158/438 (36%), Gaps = 41/438 (9%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQ-QSRTIQISWTQPYAGNS-PIINYIVQYKEAP 111
S+ + L + +LS P ++ RV+ + + + + + W P + + + Y V+ E P
Sbjct: 656 SQCSESLPVRTLSI-APGQCRSPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE-P 713
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
E S + G +V NL P T Y R+ A N G S ++TT +G
Sbjct: 714 EDVASE----VYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTA----AG 765
Query: 172 PPQDVRVEAKSSTE---LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS 228
PP + S T ++V WE P D +I Y + + E + S LI G
Sbjct: 766 PPGQCKAPCISCTPDGCVLVGWESP--DSSGADISEYRLEWGE-DEESLELIYHGT-DTR 821
Query: 229 YTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG 288
+ +R + A R Y+ +V E + + P
Sbjct: 822 FEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDS 881
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS 348
C L +WE P G + Y + + GN + +H +
Sbjct: 882 PSACLVL-------NWEEPCNNGSE--ILAYTIDLGDTSITVGN--------TTMH-VMK 923
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPS 408
L T Y + + A G G + + T +P P ++ A + + + W +
Sbjct: 924 DLLPETTYRIRIQAINEIGAGPFSQFIKAKT-RPLPPLPPRLECAAAGPQSLKLKWGDSN 982
Query: 409 SPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEG 468
S +Y +ED R + PS +++ R + F + A++ GEG
Sbjct: 983 SKTHAAED-IVYTLQLED-RNKRFISIYRGPSH-TYKVQRLTEFTCYSFRIQAASEAGEG 1039
Query: 469 EATRVVTVLPSDSVPARI 486
+ T + SVP I
Sbjct: 1040 PFSETYTFSTTKSVPPTI 1057
Score = 33.9 bits (74), Expect = 3.2
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 957 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 1016
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 1017 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWET 1076
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 1077 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 1127
Score = 32.7 bits (71), Expect = 7.5
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISW-TQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
S + VP K RV + + +I W T P P+ NYI+Q ES K +
Sbjct: 1048 STTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPV-NYILQVLVGRES----EYKQV 1102
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENR 150
G + + LQ T Y R+ A R
Sbjct: 1103 YKGEEATFQISGLQTNTDYRFRVCACRR 1130
>AB098597-1|BAC53727.1| 1204|Homo sapiens FAD104 protein.
Length = 1204
Score = 79.8 bits (188), Expect = 5e-14
Identities = 162/718 (22%), Positives = 264/718 (36%), Gaps = 75/718 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
PE P ++ + ++ + W P S I NY++++ E ++ + GS
Sbjct: 379 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKR---NSGFRQCFFGSQKH 435
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA Y R+ A N +G S SQ V T +P P V A T + +
Sbjct: 436 CKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQ 494
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P+ ++ Y + QE + N + YT + T+ L
Sbjct: 495 WSKPE-GCSPEEVITYTLEIQE-DENDNLF------HPKYTGEDL--------TCTVKNL 538
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A N+ D P P L ++S V W+PP
Sbjct: 539 KRSTQYTFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKD 598
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTVCAFTA 365
G + IL+ Y + +TD GN +A ++ SG T T + L+ T Y + C +
Sbjct: 599 NGGSEILK-YLL---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCIST 652
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YTLYMSV 423
G + + T P + ++K + + W P+S +G V Y++ M+
Sbjct: 653 GGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE 712
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
ED E H P L P ++F V A G G + V + + P
Sbjct: 713 PEDVASEVYH----GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPP 767
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSSDGTLT 539
+ + P C VG +P ++ ++ L E + GT T
Sbjct: 768 GQCKA-------PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDT 820
Query: 540 -ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAV-----VDSYAD 587
+ + Y C ++ N G + V + P P L V +D+Y D
Sbjct: 821 RFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPD 880
Query: 588 S----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLY 643
S L L W + + GS IL Y I+ GD + V T+ HV+ +L T Y++
Sbjct: 881 SPSACLVLNWEEPCNNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPETTYRIR 934
Query: 644 ITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
I A N IG G + A T+ P+ P+ + W DS + ++
Sbjct: 935 IQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHAAEDIV 992
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
++ R +S + + V LT Y RI A + AG Y F+T
Sbjct: 993 YTLQLEDRNKRFIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFST 1049
Score = 60.1 bits (139), Expect = 4e-08
Identities = 125/613 (20%), Positives = 218/613 (35%), Gaps = 55/613 (8%)
Query: 77 RVIDQQSRTIQISWTQPYA---GNSPIINYIVQYKEA-PESWPSTPQKVIVPGSVTSASV 132
+V + Q+R + +SW P G +++ Y+ A + K+I G ++
Sbjct: 283 QVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNL 342
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-PQDVRVEAKSSTELIVTWE 191
++L+PAT YH+R+ A + S+PV TT P P P + +KSS L + W+
Sbjct: 343 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSS--LTLQWK 400
Query: 192 PPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P + NG+ I Y + + E N SG + ++ L+ L
Sbjct: 401 AP---IDNGSKITNYLLEWDEGKRN------SGFRQCFF---------GSQKHCKLTKLC 442
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + A N + ++P +P A V + W P
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKP--- 498
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFTAAGD 368
G +TY N++ + +G L T+ L+R T Y+ + A G
Sbjct: 499 --EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYTFRLTASNTEGK 556
Query: 369 GVRAAPVYCHTEEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ + C T D P P +K V+S V W PP G + Y+ I D
Sbjct: 557 SCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHG-FSVKWDPPKDNGGSEI--LKYLLEITD 613
Query: 427 GREEGTHKRM-LSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR 485
G E + S S + + P ++ + G + + + V P +
Sbjct: 614 GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQ 673
Query: 486 ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG------TLT 539
R + P + + L + VPA + ++ +E T ++V+S+ T
Sbjct: 674 CRP-PRVLGRPKHKEVHLEWD---VPASESGCEVSEYSVEMTEPEDVASEVYHGPELECT 729
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPP---ILAVVDSYADSLHL-QWSD 595
+ + N G + E+ PP + D L W
Sbjct: 730 VGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWES 789
Query: 596 QGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
G+ I Y + + E + EL + + +L +Y + AFN+ G G
Sbjct: 790 PDSSGADISEYRLEW-GEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPY 848
Query: 656 CDIVHAYTKGTVP 668
++V T + P
Sbjct: 849 SELVLCQTPASAP 861
Score = 60.1 bits (139), Expect = 4e-08
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 474 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 529
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 530 DLTCTVKNLKRSTQYTFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 589
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 590 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 633
Score = 57.2 bits (132), Expect = 3e-07
Identities = 72/295 (24%), Positives = 112/295 (37%), Gaps = 17/295 (5%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK-VGVPAPAT-TWTMNGVGL 524
E E RV +L P +R +V W + LSC G+ P + ++ G
Sbjct: 266 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGR 325
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSV----ENIHGR--DEVTYTVEVKVP--PQP 576
+ K + S L ++ + +Y V ++ G + V++T P P P
Sbjct: 326 DGKY-KIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFP 384
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LPNLW 635
P LA SL LQW D GS I Y++ + + Q G+ +H L L
Sbjct: 385 PKLA--HRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLC 442
Query: 636 CGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDG 694
Y + A N IGT V YT G +P P +++ T VT+ W G
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCS 502
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + +E +E L + +V L + Y R+TA N G
Sbjct: 503 PEEVITYTLEIQEDEND--NLFHPKYTGEDLTCTVKNLKRSTQYTFRLTASNTEG 555
Score = 33.9 bits (74), Expect = 3.2
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 957 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 1016
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 1017 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWET 1076
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 1077 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 1127
Score = 32.7 bits (71), Expect = 7.5
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISW-TQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
S + VP K RV + + +I W T P P+ NYI+Q ES K +
Sbjct: 1048 STTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPV-NYILQVLVGRES----EYKQV 1102
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENR 150
G + + LQ T Y R+ A R
Sbjct: 1103 YKGEEATFQISGLQTNTDYRFRVCACRR 1130
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/317 (24%), Positives = 130/317 (41%), Gaps = 20/317 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGS 126
+P P +V D ++ +SW G P YI++ + SW + V
Sbjct: 521 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHV----K 576
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
T +V+ L+P T Y + A N G S+PS T+++ P D R K +
Sbjct: 577 TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD 636
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQ-ELNSNSTVLIASGPG-GASYTVRTVEGAGTARSR 243
++V P + + V Q + V+ G A+ + + ++
Sbjct: 637 VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 696
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA---LQCNALSSQSV 300
L L+K Y + V+ Y + E+ PS PP + L + +S S+
Sbjct: 697 AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSI 756
Query: 301 RVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYS 357
VSW+PPP +NGI+Q Y++ T ++ N+ DA + + + GL Y
Sbjct: 757 SVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV-----IIGGLFPGIQYR 811
Query: 358 VTVCAFTAAGDGVRAAP 374
V V A T+AG GV++ P
Sbjct: 812 VEVAASTSAGVGVKSEP 828
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 480 DSVPARITSFSR--------NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
DS PA +T F R N V +E + C G P P W + L R +
Sbjct: 213 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYD 271
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
+ D TL I T S D G Y C EN G+ E + T+ V+ PPQ
Sbjct: 272 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 315
Score = 44.4 bits (100), Expect = 0.002
Identities = 75/321 (23%), Positives = 123/321 (38%), Gaps = 45/321 (14%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A R+G+ EA+ +TV P + R+ + ++ C G P PA W
Sbjct: 295 AENRVGKMEASATLTV----RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE 350
Query: 521 GVG--------LESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG------RDEVTY 566
G + R +VS G LTI+ Q +D+G Y C + G + EVT
Sbjct: 351 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD 410
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYV-INYKREHGDWEELQV 622
+ + PP Q P + +L L+ GD P++ ++ + D
Sbjct: 411 VLTDRPPPIILQGPANQTLAVDGTAL-LKCKATGD-PLPVISWLKEGFTFPGRDPRATIQ 468
Query: 623 EAGTSEHVLPNLW---CGTRYQLYITAFNRIGTGLPCDIVHA-------YTKGTVPVKPK 672
E GT + + NL GT + ++ D+ + Y +P P
Sbjct: 469 EQGTLQ--IKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS 526
Query: 673 HSQMITLNTTTVTVWLDSWGDGGCGIL----YFVIEYREMSQPQWRLVSNSVQATERVFS 728
Q+ + +VT+ SW G G L Y + + + W+ V+N V+ T +++
Sbjct: 527 KPQVTDVTKNSVTL---SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTT--LYT 581
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GL P Y + A N G
Sbjct: 582 VRGLRPNTIYLFMVRAINPQG 602
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 492 NIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++V E L C G P P W + V ++ + G L IS T+ +D+G
Sbjct: 141 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM 200
Query: 551 YTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
YTC N+ G + + E+ V +P L
Sbjct: 201 YTCVGTNMVGERD-SDPAELTVFERPTFL 228
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/317 (24%), Positives = 130/317 (41%), Gaps = 20/317 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGS 126
+P P +V D ++ +SW G P YI++ + SW + V
Sbjct: 537 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHV----K 592
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
T +V+ L+P T Y + A N G S+PS T+++ P D R K +
Sbjct: 593 TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD 652
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQ-ELNSNSTVLIASGPG-GASYTVRTVEGAGTARSR 243
++V P + + V Q + V+ G A+ + + ++
Sbjct: 653 VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 712
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA---LQCNALSSQSV 300
L L+K Y + V+ Y + E+ PS PP + L + +S S+
Sbjct: 713 AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSI 772
Query: 301 RVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYS 357
VSW+PPP +NGI+Q Y++ T ++ N+ DA + + + GL Y
Sbjct: 773 SVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV-----IIGGLFPGIQYR 827
Query: 358 VTVCAFTAAGDGVRAAP 374
V V A T+AG GV++ P
Sbjct: 828 VEVAASTSAGVGVKSEP 844
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 480 DSVPARITSFSR--------NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
DS PA +T F R N V +E + C G P P W + L R +
Sbjct: 229 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYD 287
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
+ D TL I T S D G Y C EN G+ E + T+ V+ PPQ
Sbjct: 288 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 331
Score = 44.4 bits (100), Expect = 0.002
Identities = 75/321 (23%), Positives = 123/321 (38%), Gaps = 45/321 (14%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A R+G+ EA+ +TV P + R+ + ++ C G P PA W
Sbjct: 311 AENRVGKMEASATLTV----RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE 366
Query: 521 GVG--------LESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG------RDEVTY 566
G + R +VS G LTI+ Q +D+G Y C + G + EVT
Sbjct: 367 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD 426
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYV-INYKREHGDWEELQV 622
+ + PP Q P + +L L+ GD P++ ++ + D
Sbjct: 427 VLTDRPPPIILQGPANQTLAVDGTAL-LKCKATGD-PLPVISWLKEGFTFPGRDPRATIQ 484
Query: 623 EAGTSEHVLPNLW---CGTRYQLYITAFNRIGTGLPCDIVHA-------YTKGTVPVKPK 672
E GT + + NL GT + ++ D+ + Y +P P
Sbjct: 485 EQGTLQ--IKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS 542
Query: 673 HSQMITLNTTTVTVWLDSWGDGGCGIL----YFVIEYREMSQPQWRLVSNSVQATERVFS 728
Q+ + +VT+ SW G G L Y + + + W+ V+N V+ T +++
Sbjct: 543 KPQVTDVTKNSVTL---SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTT--LYT 597
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GL P Y + A N G
Sbjct: 598 VRGLRPNTIYLFMVRAINPQG 618
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 492 NIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++V E L C G P P W + V ++ + G L IS T+ +D+G
Sbjct: 157 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM 216
Query: 551 YTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
YTC N+ G + + E+ V +P L
Sbjct: 217 YTCVGTNMVGERD-SDPAELTVFERPTFL 244
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/335 (23%), Positives = 137/335 (40%), Gaps = 26/335 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQ-YKEAP-ESWPSTPQKVIVPGS 126
+P P V D T+ +SW + +YI++ + A SW + + V
Sbjct: 199 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV----K 254
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
+++++ L+P Y + A N G S+PSQ T++V P+ D + +
Sbjct: 255 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN 314
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR---TVEGAGTARS 242
++ P L + +I ++ Q+ I P GA++ E A++
Sbjct: 315 AVLHLHNPTV-LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN 373
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC--NALSSQSV 300
+ L+K Y + + + + +E+ PS PP + N + ++
Sbjct: 374 SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAI 433
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDA--VTKQISG--LHTTLSGLRRYTN 355
VSW+PPP +NG++Q Y+V W GNE + K + G + L
Sbjct: 434 LVSWQPPPEDTQNGMVQEYKV-------WCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 486
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAPAD 389
YSV V A T AG GV++ P + + P +P D
Sbjct: 487 YSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPED 521
Score = 44.8 bits (101), Expect = 0.002
Identities = 67/281 (23%), Positives = 101/281 (35%), Gaps = 35/281 (12%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGL--------ESTLRKNVSSDGTLTISMTQSADSGNYT 552
++ C G P PA W G +S+ R +VS G LTI+ Q +D G Y
Sbjct: 3 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 62
Query: 553 CSVENIHGRD------EVTYTVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPI 603
C N+ G EVT + + PP Q P+ V + + L G I
Sbjct: 63 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTV-AVDGTFVLSCVATGSPVPTI 121
Query: 604 LGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRY-------------QLYITAFNRI 650
L D Q+E G + L RY YI ++
Sbjct: 122 LWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQGKV 181
Query: 651 GT-GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
G+P +P P ++ ++ TVT+ W + G Y + +
Sbjct: 182 NEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHA 241
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
S W+ V+ +V+ TE ++ GL P A Y + A N G
Sbjct: 242 SGSSWQTVAENVK-TE-TSAIKGLKPNAIYLFLVRAANAYG 280
Score = 43.2 bits (97), Expect = 0.005
Identities = 51/209 (24%), Positives = 74/209 (35%), Gaps = 25/209 (11%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
VT + +D P I N LSC G P P W +GV L ST +
Sbjct: 80 VTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIK 138
Query: 534 --SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK-------VPPQPP------I 578
+G L I + D+G YTC G + +EV+ VP QPP +
Sbjct: 139 QLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQGKVNEFGVPVQPPRPTDPNL 198
Query: 579 L-------AVVDSYADSLHLQWSDQGDGGSPILGYVIN-YKREHG-DWEELQVEAGTSEH 629
+ V D +++ L W + G+ Y+I + G W+ + T
Sbjct: 199 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETS 258
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDI 658
+ L Y + A N G P I
Sbjct: 259 AIKGLKPNAIYLFLVRAANAYGISDPSQI 287
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/335 (23%), Positives = 137/335 (40%), Gaps = 26/335 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQ-YKEAP-ESWPSTPQKVIVPGS 126
+P P V D T+ +SW + +YI++ + A SW + + V
Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV----K 579
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
+++++ L+P Y + A N G S+PSQ T++V P+ D + +
Sbjct: 580 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN 639
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR---TVEGAGTARS 242
++ P L + +I ++ Q+ I P GA++ E A++
Sbjct: 640 AVLHLHNPTV-LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN 698
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC--NALSSQSV 300
+ L+K Y + + + + +E+ PS PP + N + ++
Sbjct: 699 SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAI 758
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDA--VTKQISG--LHTTLSGLRRYTN 355
VSW+PPP +NG++Q Y+V W GNE + K + G + L
Sbjct: 759 LVSWQPPPEDTQNGMVQEYKV-------WCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 811
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAPAD 389
YSV V A T AG GV++ P + + P +P D
Sbjct: 812 YSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPED 846
Score = 52.8 bits (121), Expect = 7e-06
Identities = 75/317 (23%), Positives = 115/317 (36%), Gaps = 32/317 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G+ EA+ +TV P + R+ V ++ C G P PA W
Sbjct: 293 AENMVGKAEASATLTVQVGSEPPHFVVK-PRDQVVALGRTVTFQCEATGNPQPAIFWRRE 351
Query: 521 GVGL--------ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD------EVTY 566
G +S+ R +VS G LTI+ Q +D G Y C N+ G EVT
Sbjct: 352 GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVE 623
+ + PP Q P+ V + + L G IL D Q+E
Sbjct: 412 VIADRPPPVIRQGPVNQTV-AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGT----------GLPCDIVHAYTKGTVPVKPKH 673
G + L RY + + T G+P +P P
Sbjct: 471 NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
++ ++ TVT+ W + G Y + + S W+ V+ +V+ TE ++ GL
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK-TE-TSAIKGL 588
Query: 733 TPAAHYQLRITAHNNAG 749
P A Y + A N G
Sbjct: 589 KPNAIYLFLVRAANAYG 605
Score = 52.4 bits (120), Expect = 9e-06
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY 551
N+ ++ C G P P W + L + R + D TL I + D G+Y
Sbjct: 231 NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSY 289
Query: 552 TCSVENIHGRDEVTYTVEVKVPPQPPILAV 581
TC EN+ G+ E + T+ V+V +PP V
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVV 319
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
G P P +W +G L+ + G L I+ T+ +D+G Y C N+ G E +
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERE-SEVA 215
Query: 569 EVKVPPQP 576
E+ V +P
Sbjct: 216 ELTVLERP 223
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 79.0 bits (186), Expect = 9e-14
Identities = 72/287 (25%), Positives = 118/287 (41%), Gaps = 14/287 (4%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTI 540
PA ++I P +C G P P TW NG +G +R +++ TLTI
Sbjct: 329 PAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLK-NNNSTLTI 387
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQ 596
S D Y C EN G + + + V +P P + V + + + WS+
Sbjct: 388 SGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEP 447
Query: 597 GDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNRIGT 652
I+GYV++ R+ D EL+ V T +H++ +L T Y YI A+ G
Sbjct: 448 LANTKEIIGYVLHI-RKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGA 506
Query: 653 GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQ 712
A T G P P S + +++ +W + W F + YR S+
Sbjct: 507 SSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLLW-EPWPRLAQHEGGFKLFYRPASKTS 565
Query: 713 WRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
+ + T +++S L P A Y++++ A+N G A F +
Sbjct: 566 F-TGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVS 611
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 3/124 (2%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
+P P+N+R + S +++SW++P A II Y++ ++A + P + V S
Sbjct: 423 LPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADP-PELEYQEAVSKSTF 481
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V +L+P+T+Y I A G S S P +T E P+ PP VRV SS +L+
Sbjct: 482 QHLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLL- 540
Query: 189 TWEP 192
WEP
Sbjct: 541 -WEP 543
Score = 71.3 bits (167), Expect = 2e-11
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 26/268 (9%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
++ ++ + P + +AEN G S+ S + V E +P GPP++VR + SSTE+
Sbjct: 383 STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLP-GPPRNVRAVSVSSTEVR 441
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V+W P + I+GY + ++ A+ P Y E + + +S
Sbjct: 442 VSWSEPLAN--TKEIIGYVLHIRK---------AADPPELEYQ----EAVSKSTFQHLVS 486
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L+ AY+ ++AY R + + P+ PP L L S S+++ WEP
Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPP--LSVRVLGSSSLQLLWEPW 544
Query: 308 PMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P ++ G+++ Y P + + + +S + LS L Y V + A+
Sbjct: 545 PRLAQHE--GGFKLFYRPASKTSFTGPILLPGTVSSYN--LSQLDPTAVYEVKLLAYNQH 600
Query: 367 GDG---VRAAPVYCHTEEDVPSAPADIK 391
GDG VR + +E S P D +
Sbjct: 601 GDGNATVRFVSLRGASERTALSPPCDCR 628
Score = 50.4 bits (115), Expect = 3e-05
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 1/126 (0%)
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
T+SG+ A +AG +A + E +P P +++A S ++ VSW
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWS 445
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
P + ++GY L++ D E ++ +S ST H S P + F++ A T
Sbjct: 446 EPLANTKEIIGYVLHIRKAADPPEL-EYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPR 504
Query: 466 GEGEAT 471
G A+
Sbjct: 505 GASSAS 510
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 6/66 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQ------SADSGNYTCS 554
I L C G P TW NGV L + + ++G+L I + +D G+Y C
Sbjct: 59 IVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECV 118
Query: 555 VENIHG 560
+N G
Sbjct: 119 AQNRFG 124
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES 113
S +V +L P ++RV+ S +Q+ W +P+ + + P S
Sbjct: 507 SSASVPTLASTLGEAPAPPPLSVRVLGSSS--LQLLW-EPWPRLAQHEGGFKLFYR-PAS 562
Query: 114 WPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVT-TTEEVPSG 171
S +++PG+V+S ++ L P Y ++++A N+ G + + V + +E
Sbjct: 563 KTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGASERTALS 622
Query: 172 PPQDVRVE 179
PP D R E
Sbjct: 623 PPCDCRKE 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 505 CNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
C G+P P TW N V +++ R + G L I+ ++ D G + C NI
Sbjct: 160 CQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNI 214
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 79.0 bits (186), Expect = 9e-14
Identities = 72/287 (25%), Positives = 118/287 (41%), Gaps = 14/287 (4%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTI 540
PA ++I P +C G P P TW NG +G +R +++ TLTI
Sbjct: 329 PAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLK-NNNSTLTI 387
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVK----VPPQPPILAVVDSYADSLHLQWSDQ 596
S D Y C EN G + + + V +P P + V + + + WS+
Sbjct: 388 SGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEP 447
Query: 597 GDGGSPILGYVINYKREHGDWEELQ----VEAGTSEHVLPNLWCGTRYQLYITAFNRIGT 652
I+GYV++ R+ D EL+ V T +H++ +L T Y YI A+ G
Sbjct: 448 LANTKEIIGYVLHI-RKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGA 506
Query: 653 GLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQ 712
A T G P P S + +++ +W + W F + YR S+
Sbjct: 507 SSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLLW-EPWPRLAQHEGGFKLFYRPASKTS 565
Query: 713 WRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALYNFTT 759
+ + T +++S L P A Y++++ A+N G A F +
Sbjct: 566 F-TGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVS 611
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 3/124 (2%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
+P P+N+R + S +++SW++P A II Y++ ++A + P + V S
Sbjct: 423 LPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADP-PELEYQEAVSKSTF 481
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
V +L+P+T+Y I A G S S P +T E P+ PP VRV SS +L+
Sbjct: 482 QHLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLL- 540
Query: 189 TWEP 192
WEP
Sbjct: 541 -WEP 543
Score = 71.3 bits (167), Expect = 2e-11
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 26/268 (9%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
++ ++ + P + +AEN G S+ S + V E +P GPP++VR + SSTE+
Sbjct: 383 STLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLP-GPPRNVRAVSVSSTEVR 441
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
V+W P + I+GY + ++ A+ P Y E + + +S
Sbjct: 442 VSWSEPLAN--TKEIIGYVLHIRK---------AADPPELEYQ----EAVSKSTFQHLVS 486
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
L+ AY+ ++AY R + + P+ PP L L S S+++ WEP
Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPP--LSVRVLGSSSLQLLWEPW 544
Query: 308 PMRGRNGILQGYRVTYAPVTDW-YGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAA 366
P ++ G+++ Y P + + + +S + LS L Y V + A+
Sbjct: 545 PRLAQHE--GGFKLFYRPASKTSFTGPILLPGTVSSYN--LSQLDPTAVYEVKLLAYNQH 600
Query: 367 GDG---VRAAPVYCHTEEDVPSAPADIK 391
GDG VR + +E S P D +
Sbjct: 601 GDGNATVRFVSLRGASERTALSPPCDCR 628
Score = 50.4 bits (115), Expect = 3e-05
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 1/126 (0%)
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
T+SG+ A +AG +A + E +P P +++A S ++ VSW
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWS 445
Query: 406 PPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRL 465
P + ++GY L++ D E ++ +S ST H S P + F++ A T
Sbjct: 446 EPLANTKEIIGYVLHIRKAADPPEL-EYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPR 504
Query: 466 GEGEAT 471
G A+
Sbjct: 505 GASSAS 510
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 6/66 (9%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQ------SADSGNYTCS 554
I L C G P TW NGV L + + ++G+L I + +D G+Y C
Sbjct: 59 IVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECV 118
Query: 555 VENIHG 560
+N G
Sbjct: 119 AQNRFG 124
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES 113
S +V +L P ++RV+ S +Q+ W +P+ + + P S
Sbjct: 507 SSASVPTLASTLGEAPAPPPLSVRVLGSSS--LQLLW-EPWPRLAQHEGGFKLFYR-PAS 562
Query: 114 WPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPS-QPVQVT-TTEEVPSG 171
S +++PG+V+S ++ L P Y ++++A N+ G + + V + +E
Sbjct: 563 KTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGASERTALS 622
Query: 172 PPQDVRVE 179
PP D R E
Sbjct: 623 PPCDCRKE 630
Score = 32.3 bits (70), Expect = 9.9
Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 505 CNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
C G+P P TW N V +++ R + G L I+ ++ D G + C NI
Sbjct: 160 CQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNI 214
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/317 (24%), Positives = 130/317 (41%), Gaps = 20/317 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGS 126
+P P +V D ++ +SW G P YI++ + SW + V
Sbjct: 242 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHV----K 297
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
T +V+ L+P T Y + A N G S+PS T+++ P D R K +
Sbjct: 298 TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD 357
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQ-ELNSNSTVLIASGPG-GASYTVRTVEGAGTARSR 243
++V P + + V Q + V+ G A+ + + ++
Sbjct: 358 VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 417
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA---LQCNALSSQSV 300
L L+K Y + V+ Y + E+ PS PP + L + +S S+
Sbjct: 418 AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSI 477
Query: 301 RVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYS 357
VSW+PPP +NGI+Q Y++ T ++ N+ DA + + + GL Y
Sbjct: 478 SVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV-----IIGGLFPGIQYR 532
Query: 358 VTVCAFTAAGDGVRAAP 374
V V A T+AG GV++ P
Sbjct: 533 VEVAASTSAGVGVKSEP 549
Score = 48.8 bits (111), Expect = 1e-04
Identities = 75/321 (23%), Positives = 123/321 (38%), Gaps = 41/321 (12%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A R+G+ EA+ +TV P + R+ + ++ C G P PA W
Sbjct: 12 AENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE 71
Query: 521 GVG--------LESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG------RDEVTY 566
G + R +VS G LTI+ Q +D+G Y C + G + EVT
Sbjct: 72 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD 131
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYV-INYKREHGDWEELQV 622
+ + PP Q P + +L L+ GD P++ ++ + D
Sbjct: 132 VLTDRPPPIILQGPANQTLAVDGTAL-LKCKATGD-PLPVISWLKEGFTFPGRDPRATIQ 189
Query: 623 EAGTSEHVLPNLW---CGTRYQLYITAFNRIGTGLPCDIVHA-------YTKGTVPVKPK 672
E GT + + NL GT + ++ D+ + Y +P P
Sbjct: 190 EQGTLQ--IKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS 247
Query: 673 HSQMITLNTTTVTVWLDSWGDGGCGIL----YFVIEYREMSQPQWRLVSNSVQATERVFS 728
Q+ + +VT+ SW G G L Y + + + W+ V+N V+ T +++
Sbjct: 248 KPQVTDVTKNSVTL---SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTT--LYT 302
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GL P Y + A N G
Sbjct: 303 VRGLRPNTIYLFMVRAINPQG 323
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/335 (23%), Positives = 137/335 (40%), Gaps = 26/335 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQ-YKEAP-ESWPSTPQKVIVPGS 126
+P P V D T+ +SW + +YI++ + A SW + + V
Sbjct: 560 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV----K 615
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
+++++ L+P Y + A N G S+PSQ T++V P+ D + +
Sbjct: 616 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN 675
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR---TVEGAGTARS 242
++ P L + +I ++ Q+ I P GA++ E A++
Sbjct: 676 AVLHLHNPTV-LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN 734
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC--NALSSQSV 300
+ L+K Y + + + + +E+ PS PP + N + ++
Sbjct: 735 SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAI 794
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDA--VTKQISG--LHTTLSGLRRYTN 355
VSW+PPP +NG++Q Y+V W GNE + K + G + L
Sbjct: 795 LVSWQPPPEDTQNGMVQEYKV-------WCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 847
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAPAD 389
YSV V A T AG GV++ P + + P +P D
Sbjct: 848 YSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPED 882
Score = 50.4 bits (115), Expect = 3e-05
Identities = 75/317 (23%), Positives = 114/317 (35%), Gaps = 35/317 (11%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G+ EA+ +TV P R+ V ++ C G P PA W
Sbjct: 332 AENMVGKAEASATLTV----QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRRE 387
Query: 521 GVGL--------ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD------EVTY 566
G +S+ R +VS G LTI+ Q +D G Y C N+ G EVT
Sbjct: 388 GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 447
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVE 623
+ + PP Q P+ V + + L G IL D Q+E
Sbjct: 448 VIADRPPPVIRQGPVNQTV-AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 506
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGT----------GLPCDIVHAYTKGTVPVKPKH 673
G + L RY + + T G+P +P P
Sbjct: 507 NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 566
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
++ ++ TVT+ W + G Y + + S W+ V+ +V+ TE ++ GL
Sbjct: 567 PEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK-TE-TSAIKGL 624
Query: 733 TPAAHYQLRITAHNNAG 749
P A Y + A N G
Sbjct: 625 KPNAIYLFLVRAANAYG 641
Score = 50.0 bits (114), Expect = 5e-05
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY 551
N+ ++ C G P P W + L + R + D TL I + D G+Y
Sbjct: 270 NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSY 328
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
TC EN+ G+ E + T+ V+ PP
Sbjct: 329 TCVAENMVGKAEASATLTVQEPP 351
Score = 46.4 bits (105), Expect = 6e-04
Identities = 51/205 (24%), Positives = 74/205 (36%), Gaps = 21/205 (10%)
Query: 474 VTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVS 533
VT + +D P I N LSC G P P W +GV L ST +
Sbjct: 445 VTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIK 503
Query: 534 --SDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK---VPPQPP------IL--- 579
+G L I + D+G YTC G + +EV+ VP QPP ++
Sbjct: 504 QLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 563
Query: 580 ----AVVDSYADSLHLQWSDQGDGGSPILGYVIN-YKREHG-DWEELQVEAGTSEHVLPN 633
V D +++ L W + G+ Y+I + G W+ + T +
Sbjct: 564 PSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKG 623
Query: 634 LWCGTRYQLYITAFNRIGTGLPCDI 658
L Y + A N G P I
Sbjct: 624 LKPNAIYLFLVRAANAYGISDPSQI 648
Score = 37.1 bits (82), Expect = 0.35
Identities = 43/191 (22%), Positives = 78/191 (40%), Gaps = 15/191 (7%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
G P P +W +G L+ + G L I+ T+ +D+G Y C N+ G E +
Sbjct: 196 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERE-SEVA 254
Query: 569 EVKVPPQPPILAVVDSYA----DSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEA 624
E+ V +P + + A DS + +GD P+ + ++++ G+ + + E
Sbjct: 255 ELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD---PV--PTVRWRKDDGELPKSRYEI 309
Query: 625 GTSEHVLP--NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTT 682
+H L + G A N +G + VKP+ Q++ L
Sbjct: 310 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPR-DQVVALG-R 366
Query: 683 TVTVWLDSWGD 693
TVT ++ G+
Sbjct: 367 TVTFQCEATGN 377
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 79.0 bits (186), Expect = 9e-14
Identities = 78/317 (24%), Positives = 130/317 (41%), Gaps = 20/317 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGS 126
+P P +V D ++ +SW G P YI++ + SW + V
Sbjct: 523 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHV----K 578
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
T +V+ L+P T Y + A N G S+PS T+++ P D R K +
Sbjct: 579 TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGD 638
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQ-ELNSNSTVLIASGPG-GASYTVRTVEGAGTARSR 243
++V P + + V Q + V+ G A+ + + ++
Sbjct: 639 VLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERS 698
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGA---LQCNALSSQSV 300
L L+K Y + V+ Y + E+ PS PP + L + +S S+
Sbjct: 699 AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSI 758
Query: 301 RVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNE--DAVTKQISGLHTTLSGLRRYTNYS 357
VSW+PPP +NGI+Q Y++ T ++ N+ DA + + + GL Y
Sbjct: 759 SVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV-----IIGGLFPGIQYR 813
Query: 358 VTVCAFTAAGDGVRAAP 374
V V A T+AG GV++ P
Sbjct: 814 VEVAASTSAGVGVKSEP 830
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 480 DSVPARITSFSR--------NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKN 531
DS PA +T F R N V +E + C G P P W + L R +
Sbjct: 215 DSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYD 273
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
+ D TL I T S D G Y C EN G+ E + T+ V+ PPQ
Sbjct: 274 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 317
Score = 44.4 bits (100), Expect = 0.002
Identities = 75/321 (23%), Positives = 123/321 (38%), Gaps = 45/321 (14%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A R+G+ EA+ +TV P + R+ + ++ C G P PA W
Sbjct: 297 AENRVGKMEASATLTV----RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE 352
Query: 521 GVG--------LESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG------RDEVTY 566
G + R +VS G LTI+ Q +D+G Y C + G + EVT
Sbjct: 353 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD 412
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYV-INYKREHGDWEELQV 622
+ + PP Q P + +L L+ GD P++ ++ + D
Sbjct: 413 VLTDRPPPIILQGPANQTLAVDGTAL-LKCKATGD-PLPVISWLKEGFTFPGRDPRATIQ 470
Query: 623 EAGTSEHVLPNLW---CGTRYQLYITAFNRIGTGLPCDIVHA-------YTKGTVPVKPK 672
E GT + + NL GT + ++ D+ + Y +P P
Sbjct: 471 EQGTLQ--IKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS 528
Query: 673 HSQMITLNTTTVTVWLDSWGDGGCGIL----YFVIEYREMSQPQWRLVSNSVQATERVFS 728
Q+ + +VT+ SW G G L Y + + + W+ V+N V+ T +++
Sbjct: 529 KPQVTDVTKNSVTL---SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTT--LYT 583
Query: 729 VSGLTPAAHYQLRITAHNNAG 749
V GL P Y + A N G
Sbjct: 584 VRGLRPNTIYLFMVRAINPQG 604
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 492 NIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
++V E L C G P P W + V ++ + G L IS T+ +D+G
Sbjct: 143 DVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM 202
Query: 551 YTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
YTC N+ G + + E+ V +P L
Sbjct: 203 YTCVGTNMVGERD-SDPAELTVFERPTFL 230
>BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein.
Length = 1212
Score = 78.2 bits (184), Expect = 2e-13
Identities = 94/433 (21%), Positives = 181/433 (41%), Gaps = 48/433 (11%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE 112
+K+T+ + +P P N+ + + + ++W +P G +P+ + +
Sbjct: 485 NKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIGSG 544
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS-- 170
+W + + P +V +L+ SY R+ A N+ G S+PS+P + P+
Sbjct: 545 TWEAISSES--PVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATL 602
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
PP V+ + T + +TW+P + + +LGYY+ +++ ++ + + P
Sbjct: 603 PPPAQVQAFRDTQTSVSLTWDPVK----DPELLGYYIYSRKVGTSEWQTVNNKP------ 652
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED---VPSLPP 287
++G +R T+ GL+ Y V++ + ++ PS P
Sbjct: 653 ---IQG-----TRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPY 704
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYG-NEDAVTKQISGLH 344
G N ++ V + W+PP RG IL GY + + DW+ N+ + ++
Sbjct: 705 GFALLNCGKNEMV-IGWKPPKRRGGGKIL-GYFLDQHDSEELDWHAVNQQPIPTRV---- 758
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSSRNKI 400
+S L Y A AG G +AP ++ P P D++A+ +
Sbjct: 759 CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSL 818
Query: 401 LVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS--H-ETSRSPPRATHQ 456
++ W PP G + GY ++S E+G E+ + ++P +S H S P ++
Sbjct: 819 VLQWEPPLYMGAGPVTGY--HVSFQEEGSEQW---KPVTPGPISGTHLRVSDLQPGKSYV 873
Query: 457 FWVSASTRLGEGE 469
F V A G G+
Sbjct: 874 FQVQAMNSAGLGQ 886
Score = 67.7 bits (158), Expect = 2e-10
Identities = 87/375 (23%), Positives = 146/375 (38%), Gaps = 36/375 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P N+R +D + ++W P +PI Y ++ + W + + PG
Sbjct: 373 PGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE---APGGT 429
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-----PQDVRVEAKS 182
+Q L SY R+ A +R+G S PS+ ++ + + P D+ +
Sbjct: 430 CRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITI 489
Query: 183 STELI---VTWEPPQRDLWNGNILGYYV--GFQELNSNS----TVLIASGPGGASYTVRT 233
ST+ VT P ++ I YV ++E + T + G S T
Sbjct: 490 STDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIG-SGTWEA 548
Query: 234 VEGAGTARS-RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL--PPGAL 290
+ RS R + L+K +Y V+A N + P+ PP +
Sbjct: 549 ISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQV 608
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGLHTTLS 348
Q + SV ++W+P ++ L GY + V ++W + K I G T+
Sbjct: 609 QAFRDTQTSVSLTWDPV----KDPELLGYYIYSRKVGTSEW---QTVNNKPIQGTRFTVP 661
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
GLR Y V + + AG G +A P+ PSAP +N++++ W
Sbjct: 662 GLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWK 721
Query: 406 PPS-SPNGVLVGYTL 419
PP G ++GY L
Sbjct: 722 PPKRRGGGKILGYFL 736
Score = 64.9 bits (151), Expect = 2e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 23/219 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P P +++ + I W P G I+ Y + ++ E W + Q+ I P V
Sbjct: 700 PSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPI-PTRV 758
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPS-GPPQDVRVEAKSST 184
V +L Y R A N G E S P + +E +P GPP DVR +T
Sbjct: 759 --CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRAT 816
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
L++ WEPP + G + GY+V FQE S + GP + G +
Sbjct: 817 SLVLQWEPPLY-MGAGPVTGYHVSFQEEGSEQWKPVTPGP---------ISG-----THL 861
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
+S LQ +Y VQA NS +ED P
Sbjct: 862 RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKP 900
Score = 56.0 bits (129), Expect = 7e-07
Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKE-APESW-PSTPQKVIVPGS 126
P P ++R + ++ ++ + W P Y G P+ Y V ++E E W P TP P S
Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPG----PIS 857
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T V +LQP SY ++ A N G +PS P E+ P +V V+ + +
Sbjct: 858 GTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGF--I 915
Query: 187 IVTWEPPQ 194
+ +E P+
Sbjct: 916 YLAFEAPE 923
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/185 (28%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 487 TSFSRNIVTPWKENISLSC--NKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTIS 541
TS + + KE SLSC ++ + A + W +G L S+ R+ + +L +S
Sbjct: 274 TSVLKPVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVS 333
Query: 542 MTQSADSGNYTCSVENIHG-RDEVTYTV----EVKVPPQP--PI-LAVVDSYADSLHLQW 593
T D G Y V + G R++ TY + E + P P P+ + +D D L L W
Sbjct: 334 CTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTW 393
Query: 594 SDQGDG-GSPILGYVINY-KREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ D G+PI Y I + E G+W + GT + L G Y+ + A +R+
Sbjct: 394 APPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRV 453
Query: 651 GTGLP 655
G+ +P
Sbjct: 454 GSSVP 458
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGL 343
PP ++ + + + S+ + WEPP G G + GY V++ W + ISG
Sbjct: 804 PPYDVRASEVRATSLVLQWEPPLYMGA-GPVTGYHVSFQEEGSEQW---KPVTPGPISGT 859
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
H +S L+ +Y V A +AG G + P ED P A +I+ V I ++
Sbjct: 860 HLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGA-HEIEVGVDEEGFIYLA 918
Query: 404 WLPPSSPN 411
+ P +P+
Sbjct: 919 FEAPEAPD 926
Score = 39.1 bits (87), Expect = 0.086
Identities = 115/549 (20%), Positives = 198/549 (36%), Gaps = 58/549 (10%)
Query: 152 GQSEPSQPVQVTTTE-EVPSGP--PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVG 208
G E S V V E E P P P +VR + LI+TW PP D I Y +
Sbjct: 352 GPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPS-DTRGNPITAYTIE 410
Query: 209 FQELNSNSTVLIASGPGGASYTV--RTVEGAG-----TARSRTTLSGLQKHAAYAVVVQA 261
+ S + PGG VEG A SR S + A+ VV+
Sbjct: 411 RCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRVG-SSVPSKASELVVMGD 469
Query: 262 YNSRXXXXXX-------XXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEPPPMRGR 312
+++ ED ++P P + + + V ++WE P RGR
Sbjct: 470 HDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGR 529
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQ--ISGLHTTLSGLRRYTNYSVTVCAFTAAG--- 367
+ + W +A++ + + + L + +Y V A G
Sbjct: 530 APLTYSLEKSVIGSGTW----EAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSD 585
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDG 427
+ P+ PA ++A ++ + ++W P P L+GY +Y +
Sbjct: 586 PSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPE--LLGYYIYSRKVGTS 643
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT------RVVTVLPSDS 481
+ + + + + + R+ ++F V + + G GE++ RV L + S
Sbjct: 644 EWQTVNNKPIQGTRFTVPGLRTGKE--YEFCVRSVSEAGVGESSAATEPIRVKQALATPS 701
Query: 482 VP---ARITSFSRNIVTPWKENISLSCNKV-GV-----PAPATTW-TMNGVGLESTLRKN 531
P A + +V WK K+ G + W +N + + + K
Sbjct: 702 APYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCK- 760
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP-PQPPI-LAVVDSYADSL 589
SD A + N+ V + + E +P P PP + + A SL
Sbjct: 761 -VSDLHEGHFYEFRARAANW-AGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSL 818
Query: 590 HLQWSDQ-GDGGSPILGYVINYKREHGD-WEELQVEAGTSEHV-LPNLWCGTRYQLYITA 646
LQW G P+ GY ++++ E + W+ + + H+ + +L G Y + A
Sbjct: 819 VLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQA 878
Query: 647 FNRIGTGLP 655
N G G P
Sbjct: 879 MNSAGLGQP 887
Score = 32.3 bits (70), Expect = 9.9
Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Query: 497 WKEN-ISLSCNKVGVPAPATTWTMNGVGLESTL----RKNVSSD-GTLTISMTQSA--DS 548
W+ + L+C P P TW N ++ L + ++++ G L++ + + A DS
Sbjct: 166 WEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDS 225
Query: 549 GNYTCSVENIHGR 561
YT V+N HG+
Sbjct: 226 ATYTVRVKNAHGQ 238
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 77.8 bits (183), Expect = 2e-13
Identities = 78/335 (23%), Positives = 136/335 (40%), Gaps = 26/335 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQ-YKEAP-ESWPSTPQKVIVPGS 126
+P P V D T+ +SW + +YI++ + A SW + + V
Sbjct: 524 IPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV----K 579
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPPQDVRVEAKSSTE 185
+++++ L+P Y + A N G S+PSQ T++V P+ D + +
Sbjct: 580 TETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGN 639
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVR---TVEGAGTARS 242
++ P L +I ++ Q+ I P GA++ E A++
Sbjct: 640 AVLHLHNPTV-LSPSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN 698
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQC--NALSSQSV 300
+ L+K Y + + + + +E+ PS PP + N + ++
Sbjct: 699 SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAI 758
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDW-YGNEDA--VTKQISG--LHTTLSGLRRYTN 355
VSW+PPP +NG++Q Y+V W GNE + K + G + L
Sbjct: 759 LVSWQPPPEDTQNGMVQEYKV-------WCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 811
Query: 356 YSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSAPAD 389
YSV V A T AG GV++ P + + P +P D
Sbjct: 812 YSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPED 846
Score = 52.8 bits (121), Expect = 7e-06
Identities = 75/317 (23%), Positives = 115/317 (36%), Gaps = 32/317 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G+ EA+ +TV P + R+ V ++ C G P PA W
Sbjct: 293 AENMVGKAEASATLTVQVGSEPPHFVVK-PRDQVVALGRTVTFQCEATGNPQPAIFWRRE 351
Query: 521 GVGL--------ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRD------EVTY 566
G +S+ R +VS G LTI+ Q +D G Y C N+ G EVT
Sbjct: 352 GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Query: 567 TVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVE 623
+ + PP Q P+ V + + L G IL D Q+E
Sbjct: 412 VIADRPPPVIRQGPVNQTV-AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 624 AGTSEHVLPNLWCGTRYQLYITAFNRIGT----------GLPCDIVHAYTKGTVPVKPKH 673
G + L RY + + T G+P +P P
Sbjct: 471 NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSK 530
Query: 674 SQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGL 732
++ ++ TVT+ W + G Y + + S W+ V+ +V+ TE ++ GL
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK-TE-TSAIKGL 588
Query: 733 TPAAHYQLRITAHNNAG 749
P A Y + A N G
Sbjct: 589 KPNAIYLFLVRAANAYG 605
Score = 52.4 bits (120), Expect = 9e-06
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNY 551
N+ ++ C G P P W + L + R + D TL I + D G+Y
Sbjct: 231 NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSY 289
Query: 552 TCSVENIHGRDEVTYTVEVKVPPQPPILAV 581
TC EN+ G+ E + T+ V+V +PP V
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVV 319
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTV 568
G P P +W +G L+ + G L I+ T+ +D+G Y C N+ G E +
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERE-SEVA 215
Query: 569 EVKVPPQP 576
E+ V +P
Sbjct: 216 ELTVLERP 223
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 77.8 bits (183), Expect = 2e-13
Identities = 61/240 (25%), Positives = 102/240 (42%), Gaps = 16/240 (6%)
Query: 70 PEMPKNIRVIDQQSR-TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV--IVPGS 126
P P I ++++ + T +SW+ +SPI +Y +Q + T + V I+ G
Sbjct: 376 PPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGD 435
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ-VTTTEEVPSGPPQDVRVEAKSSTE 185
+ SA +L P Y R++A N +G +PS P + + T E VP P +V + E
Sbjct: 436 MESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHE 495
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTT 245
L++ WEP + NG GY V F+ N T G V + E + +
Sbjct: 496 LVIAWEPVSEEFQNGEGFGYIVAFR---PNGT------RGWKEKMVTSSEASKFIYRDES 546
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
+ L + V V YN++ E PS P ++ ++S + V+W+
Sbjct: 547 VPPL---TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK 603
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A + G A+ + +L S A + + I+ + + + C G P P +W
Sbjct: 166 AENKYGAIYASAELKILASAPTFA-LNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKG 224
Query: 521 GVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL- 579
+ R + DG+L I +D G Y C EN+ G E+ ++ VK P + +
Sbjct: 225 DRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTP 284
Query: 580 -AVVDSYADSLHLQWSDQGDGGSPIL------GYVINYKREHGDWEELQVEAGTSEHVLP 632
+ +S+ L D + G I+++ E G +E ++ +A +++ ++
Sbjct: 285 KRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIR 344
Query: 633 NL 634
N+
Sbjct: 345 NI 346
Score = 49.2 bits (112), Expect = 8e-05
Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 33/294 (11%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATT--WTMNGVGLE--------STLRKNV 532
P RI + E+I L+C + + T WT+ G ++ ++R
Sbjct: 277 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 336
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV--PPQPPILAVVDSYADSLH 590
SS L I +G Y C V+ D V+ E+ V PP PP + +V+ +S
Sbjct: 337 SS-ADLMIRNILLMHAGRYGCRVQTT--ADSVSDEAELLVRGPPGPPGIVIVEEITESTA 393
Query: 591 -LQWSDQGDGGSPILGYVINYKREHG-DWEEL----QVEAGTSEHVLP---NLWCGTRYQ 641
L WS D SPI Y + + W+ + ++ G E + N W Y+
Sbjct: 394 TLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPW--VEYE 451
Query: 642 LYITAFNRIGTGLPCDIVHAY-TKGTVP-VKPKH-SQMITLNTTTVTVW--LDSWGDGGC 696
+ A N IGTG P T VP P + S V W + G
Sbjct: 452 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 511
Query: 697 GILYFVIEYREMSQPQWR-LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
G Y ++ +R W+ + S +A++ ++ + P +++++ +NN G
Sbjct: 512 GFGY-IVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKG 564
Score = 46.0 bits (104), Expect = 7e-04
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 2/127 (1%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTK- 338
E VP P + + + ++WEP +NG GY V + P E VT
Sbjct: 476 EAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSS 535
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ S + T + V V + GDG V C E + +AP D+KA S
Sbjct: 536 EASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSV 595
Query: 398 NKILVSW 404
++ILV+W
Sbjct: 596 SEILVAW 602
Score = 45.2 bits (102), Expect = 0.001
Identities = 44/212 (20%), Positives = 87/212 (41%), Gaps = 15/212 (7%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQIS 341
P PPG + ++ + +SW P + + Y + +P + + V + I+
Sbjct: 376 PPGPPGIVIVEEITESTATLSWS--PAADNHSPISSYNLQARSPFSLGWQTVKTVPEIIT 433
Query: 342 G-LHTTLS-GLRRYTNYSVTVCAFTAAGDGVRAAPV-YCHTEEDVP-SAPADIKAAVSSR 397
G + + ++ L + Y V A G G + P T E VP +AP ++ R
Sbjct: 434 GDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRR 493
Query: 398 NKILVSWLPPSS--PNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS---HETSRSPPR 452
++++++W P S NG GY + G ++M++ S S + PP
Sbjct: 494 HELVIAWEPVSEEFQNGEGFGYIV---AFRPNGTRGWKEKMVTSSEASKFIYRDESVPPL 550
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
+ V G+G +++V + ++ P+
Sbjct: 551 TPFEVKVGVYNNKGDGPFSQIVVICSAEGEPS 582
Score = 41.9 bits (94), Expect = 0.012
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
C G P P W NGV L R + +G L I +D+G Y C EN +G +
Sbjct: 117 CKATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYG--AI 173
Query: 565 TYTVEVKVPPQPPILAV 581
+ E+K+ P A+
Sbjct: 174 YASAELKILASAPTFAL 190
Score = 39.1 bits (87), Expect = 0.086
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 501 ISLSCNKVGVPAPATTWT-MNG-VGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
+ + C +G P P TW +NG + ++ LRK S L I Q D+G Y C EN
Sbjct: 24 VKMECFALGNPVPTITWMKVNGYIPSKARLRK---SQAVLEIPNVQLDDAGIYECRAENS 80
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQGDG 599
G++ ++V P + + D+ DS L+W + G
Sbjct: 81 RGKNSFRGQLQVYTYPH-WVEKLNDTQLDSGSPLRWECKATG 121
>BC039297-1|AAH39297.1| 1204|Homo sapiens fibronectin type III domain
containing 3B protein.
Length = 1204
Score = 77.0 bits (181), Expect = 3e-13
Identities = 161/718 (22%), Positives = 264/718 (36%), Gaps = 75/718 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
PE P ++ + ++ + W P S I NY++++ E ++ + GS
Sbjct: 379 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKR---NSGFRQCFFGSQKH 435
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA Y R+ A N +G S SQ V T +P P V A T + +
Sbjct: 436 CKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQ 494
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P+ ++ Y + QE + N + YT + T+ L
Sbjct: 495 WSKPE-GCSPEEVITYTLEIQE-DENDNLF------HPKYTGEDL--------TCTVKNL 538
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A N+ D P P L ++S V W+PP
Sbjct: 539 KRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKD 598
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTVCAFTA 365
G + IL+ Y + +TD GN +A ++ SG T T + L+ T Y + C +
Sbjct: 599 NGGSEILK-YLL---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCIST 652
Query: 366 AGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YTLYMSV 423
G + + T P + ++K + + W P+S +G V Y++ M+
Sbjct: 653 GGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE 712
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
ED E H P L P ++F V A G G + V + + P
Sbjct: 713 PEDVASEVYH----GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPP 767
Query: 484 ARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSSDGTLT 539
+ + P C VG +P ++ ++ L E + GT T
Sbjct: 768 GQCKA-------PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDT 820
Query: 540 -ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAVVD-----SYAD 587
+ + Y C ++ N G + V + P P L V++ +Y D
Sbjct: 821 RFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLWQTPASAPDPVSTLCVLEEEPLDAYPD 880
Query: 588 S----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLY 643
S L L W + + GS IL Y I+ GD + V T+ HV+ +L T Y++
Sbjct: 881 SPSACLVLNWEEPCNNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPETTYRIR 934
Query: 644 ITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
I A N IG G + A T+ P+ P+ + W DS + ++
Sbjct: 935 IQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHAAEDIV 992
Query: 704 EYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
++ R +S + + V LT Y RI A + AG Y F+T
Sbjct: 993 YTLQLEDRNKRFIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFST 1049
Score = 60.5 bits (140), Expect = 3e-08
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 474 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 529
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 530 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 589
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 590 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 633
Score = 59.3 bits (137), Expect = 8e-08
Identities = 100/470 (21%), Positives = 174/470 (37%), Gaps = 44/470 (9%)
Query: 77 RVIDQQSRTIQISWTQPYA---GNSPIINYIVQYKEA-PESWPSTPQKVIVPGSVTSASV 132
+V + Q+R + +SW P G +++ Y+ A + K+I G ++
Sbjct: 283 QVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNL 342
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-PQDVRVEAKSSTELIVTWE 191
++L+PAT YH+R+ A + S+PV TT P P P + +KSS L + W+
Sbjct: 343 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSS--LTLQWK 400
Query: 192 PPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P + NG+ I Y + + E N SG + ++ L+ L
Sbjct: 401 AP---IDNGSKITNYLLEWDEGKRN------SGFRQCFF---------GSQKHCKLTKLC 442
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + A N + ++P +P A V + W P
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKP--- 498
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFTAAGD 368
G +TY N++ + +G L T+ L+R T Y + A G
Sbjct: 499 --EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGK 556
Query: 369 GVRAAPVYCHTEEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ + C T D P P +K V+S V W PP G + Y+ I D
Sbjct: 557 SCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHG-FSVKWDPPKDNGGSEI--LKYLLEITD 613
Query: 427 GREEGTHKRM-LSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPAR 485
G E + S S + + P ++ + G + + + V P +
Sbjct: 614 GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQ 673
Query: 486 ITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD 535
R + P + + L + VPA + ++ +E T ++V+S+
Sbjct: 674 CRP-PRVLGRPKHKEVHLEWD---VPASESGCEVSEYSVEMTEPEDVASE 719
Score = 58.0 bits (134), Expect = 2e-07
Identities = 72/295 (24%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK-VGVPAPAT-TWTMNGVGL 524
E E RV +L P +R +V W + LSC G+ P + ++ G
Sbjct: 266 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGR 325
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSV----ENIHGR--DEVTYTVEVKVP--PQP 576
+ K + S L ++ + +Y V ++ G + V++T P P P
Sbjct: 326 DGKY-KIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFP 384
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LPNLW 635
P LA SL LQW D GS I Y++ + + Q G+ +H L L
Sbjct: 385 PKLA--HRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLC 442
Query: 636 CGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDG 694
Y + A N IGT V YT G +P P +++ T VT+ W G
Sbjct: 443 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCS 502
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + +E +E L + +V L + Y+ R+TA N G
Sbjct: 503 PEEVITYTLEIQEDEND--NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEG 555
Score = 33.9 bits (74), Expect = 3.2
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 957 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 1016
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 1017 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWET 1076
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 1077 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 1127
Score = 32.7 bits (71), Expect = 7.5
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISW-TQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
S + VP K RV + + +I W T P P+ NYI+Q ES K +
Sbjct: 1048 STTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPV-NYILQVLVGRES----EYKQV 1102
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENR 150
G + + LQ T Y R+ A R
Sbjct: 1103 YKGEEATFQISGLQTNTDYRFRVCACRR 1130
>U42593-1|AAD00018.1| 545|Homo sapiens fibronectin protein.
Length = 545
Score = 76.2 bits (179), Expect = 6e-13
Identities = 80/348 (22%), Positives = 144/348 (41%), Gaps = 44/348 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
+ P ++V D Q +I + W +SP+ Y V P++ P + T
Sbjct: 74 DKPSQMQVTDVQDNSISVKWLP---SSSPVTGYRVT--TTPKNGPGPTKTKTAGPDQTEM 128
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+++ LQP Y + + A+N G+S+P VTT +P+ P D++ + T L W
Sbjct: 129 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA--PTDLKFTQVTPTSLSAQW 183
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
PP N + GY V T +GP ++ + A + S +SGL
Sbjct: 184 TPP-----NVQLTGYRV-------RVTPKEKTGP------MKEINLAPDS-SSVVVSGLM 224
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y V V A +E+V PP + + ++ +SW R
Sbjct: 225 VATKYEVSVYALKD-TLTSRPAQGVVTTLENVS--PPRRARVTDATETTITISW-----R 276
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
+ + G++V P + + + T++GL+ T+Y + + +T D
Sbjct: 277 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYL--YT-LNDNA 331
Query: 371 RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP-NGVLVGY 417
R++PV + AP++++ ++ N +LVSW PP + G ++ Y
Sbjct: 332 RSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY 378
Score = 61.7 bits (143), Expect = 1e-08
Identities = 90/409 (22%), Positives = 157/409 (38%), Gaps = 31/409 (7%)
Query: 346 TLSGLRRYTNYSVTVCAFTAAGDGVRAA-PVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
T+SGL+ +Y++TV A T GD ++ P+ + ++ P+ ++ N I V W
Sbjct: 35 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK-PSQMQVTDVQDNSISVKW 93
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
LP SSP + GY ++ T + P P + V A
Sbjct: 94 LPSSSP---VTGYR--VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 148
Query: 465 LGEGE---ATRVVTV-LPSDSVPARITSFSRNIVTPW-KENISLSCNKVGVPAPATTWTM 519
GE + T V T+ P+D ++T S + W N+ L+ +V V T M
Sbjct: 149 SGESQPLVQTAVTTIPAPTDLKFTQVTPTS--LSAQWTPPNVQLTGYRVRVTPKEKTGPM 206
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ L V S + S + T + G V T+E PP+
Sbjct: 207 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG---VVTTLENVSPPRR--A 261
Query: 580 AVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE-ELQVEAGTSEHVLPNLWCGT 638
V D+ ++ + W + + I G+ ++ +G + ++ + + L GT
Sbjct: 262 RVTDATETTITISWRTKTE---TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT 318
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
Y++Y+ N P ++ A T P S + L TT ++ L SW I
Sbjct: 319 DYKIYLYTLNDNARSSPV-VIDASTAIDAP-----SNLRFLATTPNSL-LVSWQPPRARI 371
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNN 747
++I+Y + P +V +++GL P Y + + A N
Sbjct: 372 TGYIIKYEKPGSPPREVVPRPRPGVTEA-TITGLEPGTEYTIYVIALKN 419
Score = 60.9 bits (141), Expect = 2e-08
Identities = 76/309 (24%), Positives = 118/309 (38%), Gaps = 36/309 (11%)
Query: 98 SPIINYIVQYKEAPESWPSTP-QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQS-E 155
SP + Y V + ++P Q+ VPGS ++A++ L+P Y + + A G S
Sbjct: 1 SPGLEYNVSVYTVKDDKENSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 60
Query: 156 PSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSN 215
S+P+ + E+ P ++V + V W P + + GY V
Sbjct: 61 SSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPS-----SSPVTGYRV-------- 105
Query: 216 STVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXX 275
T +GPG + AG ++ T+ GLQ Y V V A N
Sbjct: 106 -TTTPKNGPGPTK-----TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP---SGESQPLV 156
Query: 276 XXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDA 335
+ +P+ P L+ ++ S+ W PP N L GYRV P + G
Sbjct: 157 QTAVTTIPA--PTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTP-KEKTGPMKE 208
Query: 336 VTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVS 395
+ +SGL T Y V+V A R A T E+V S P + +
Sbjct: 209 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENV-SPPRRARVTDA 266
Query: 396 SRNKILVSW 404
+ I +SW
Sbjct: 267 TETTITISW 275
Score = 49.6 bits (113), Expect = 6e-05
Identities = 43/164 (26%), Positives = 71/164 (43%), Gaps = 17/164 (10%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+ RV D TI ISW I + Q P + + Q+ I P V S ++
Sbjct: 258 PRRARVTDATETTITISWRTK---TETITGF--QVDAVPANGQTPIQRTIKP-DVRSYTI 311
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
LQP T Y + + L + S PV + + + + P ++R A + L+V+W+P
Sbjct: 312 TGLQPGTDYKIYLYT---LNDNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQP 366
Query: 193 PQRDLWNGNILGYYVGFQELNS-NSTVLIASGPGGASYTVRTVE 235
P+ I GY + +++ S V+ PG T+ +E
Sbjct: 367 PR-----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLE 405
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 11/89 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 345 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 396
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEP 156
T A++ L+P T Y + +IA +SEP
Sbjct: 397 TEATITGLEPGTEYTIYVIALKNNQKSEP 425
>AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member 3
protein.
Length = 1437
Score = 76.2 bits (179), Expect = 6e-13
Identities = 93/433 (21%), Positives = 180/433 (41%), Gaps = 48/433 (11%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPE- 112
+K+T+ + +P P N+ + + + ++W +P + + Y ++
Sbjct: 485 NKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSG 544
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS-- 170
+W + + P +V +L+ SY R+ A N+ G S+PS+P + P+
Sbjct: 545 TWEAISSES--PVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATL 602
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
PP V+ + T + +TW+P + + +LGYY+ +++ ++ + + P
Sbjct: 603 PPPAQVQAFRDTQTSVSLTWDPVK----DPELLGYYIYSRKVGTSEWQTVNNKP------ 652
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED---VPSLPP 287
++G +R T+ GL+ Y V++ + ++ PS P
Sbjct: 653 ---IQG-----TRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPY 704
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYG-NEDAVTKQISGLH 344
G N ++ V + W+PP RG IL GY + + DW+ N+ + ++
Sbjct: 705 GFALLNCGKNEMV-IGWKPPKRRGGGKIL-GYFLDQHDSEELDWHAVNQQPIPTRV---- 758
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSSRNKI 400
+S L Y A AG G +AP ++ P P D++A+ +
Sbjct: 759 CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSL 818
Query: 401 LVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS--H-ETSRSPPRATHQ 456
++ W PP G + GY ++S E+G E+ + ++P +S H S P ++
Sbjct: 819 VLQWEPPLYMGAGPVTGY--HVSFQEEGSEQW---KPVTPGPISGTHLRVSDLQPGKSYV 873
Query: 457 FWVSASTRLGEGE 469
F V A G G+
Sbjct: 874 FQVQAMNSAGLGQ 886
Score = 67.7 bits (158), Expect = 2e-10
Identities = 87/375 (23%), Positives = 146/375 (38%), Gaps = 36/375 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P N+R +D + ++W P +PI Y ++ + W + + PG
Sbjct: 373 PGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE---APGGT 429
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-----PQDVRVEAKS 182
+Q L SY R+ A +R+G S PS+ ++ + + P D+ +
Sbjct: 430 CRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITI 489
Query: 183 STELI---VTWEPPQRDLWNGNILGYYV--GFQELNSNS----TVLIASGPGGASYTVRT 233
ST+ VT P ++ I YV ++E + T + G S T
Sbjct: 490 STDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIG-SGTWEA 548
Query: 234 VEGAGTARS-RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL--PPGAL 290
+ RS R + L+K +Y V+A N + P+ PP +
Sbjct: 549 ISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQV 608
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGLHTTLS 348
Q + SV ++W+P ++ L GY + V ++W + K I G T+
Sbjct: 609 QAFRDTQTSVSLTWDPV----KDPELLGYYIYSRKVGTSEW---QTVNNKPIQGTRFTVP 661
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
GLR Y V + + AG G +A P+ PSAP +N++++ W
Sbjct: 662 GLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWK 721
Query: 406 PPS-SPNGVLVGYTL 419
PP G ++GY L
Sbjct: 722 PPKRRGGGKILGYFL 736
Score = 64.9 bits (151), Expect = 2e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 23/219 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P P +++ + I W P G I+ Y + ++ E W + Q+ I P V
Sbjct: 700 PSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPI-PTRV 758
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPS-GPPQDVRVEAKSST 184
V +L Y R A N G E S P + +E +P GPP DVR +T
Sbjct: 759 --CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRAT 816
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
L++ WEPP + G + GY+V FQE S + GP + G +
Sbjct: 817 SLVLQWEPPLY-MGAGPVTGYHVSFQEEGSEQWKPVTPGP---------ISG-----THL 861
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
+S LQ +Y VQA NS +ED P
Sbjct: 862 RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKP 900
Score = 56.0 bits (129), Expect = 7e-07
Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKE-APESW-PSTPQKVIVPGS 126
P P ++R + ++ ++ + W P Y G P+ Y V ++E E W P TP P S
Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPG----PIS 857
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T V +LQP SY ++ A N G +PS P E+ P +V V+ + +
Sbjct: 858 GTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGF--I 915
Query: 187 IVTWEPPQ 194
+ +E P+
Sbjct: 916 YLAFEAPE 923
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/185 (28%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 487 TSFSRNIVTPWKENISLSC--NKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTIS 541
TS + + KE SLSC ++ + A + W +G L S+ R+ + +L +S
Sbjct: 274 TSVLKPVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVS 333
Query: 542 MTQSADSGNYTCSVENIHG-RDEVTYTV----EVKVPPQP--PI-LAVVDSYADSLHLQW 593
T D G Y V + G R++ TY + E + P P P+ + +D D L L W
Sbjct: 334 CTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTW 393
Query: 594 SDQGDG-GSPILGYVINY-KREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ D G+PI Y I + E G+W + GT + L G Y+ + A +R+
Sbjct: 394 APPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRV 453
Query: 651 GTGLP 655
G+ +P
Sbjct: 454 GSSVP 458
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGL 343
PP ++ + + + S+ + WEPP G G + GY V++ W + ISG
Sbjct: 804 PPYDVRASEVRATSLVLQWEPPLYMGA-GPVTGYHVSFQEEGSEQW---KPVTPGPISGT 859
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
H +S L+ +Y V A +AG G + P ED P A +I+ V I ++
Sbjct: 860 HLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGA-HEIEVGVDEEGFIYLA 918
Query: 404 WLPPSSPN 411
+ P +P+
Sbjct: 919 FEAPEAPD 926
Score = 35.9 bits (79), Expect = 0.80
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNV-SSDGTLTISMTQSADSGNYTCSV 555
+ + L+C G P P +W N V R V ++ T+TI S DSG Y V
Sbjct: 1350 KTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFV 1409
Query: 556 ENIHGRDEVTYTVEV 570
+N +G + T+ V
Sbjct: 1410 KNKYGSETGQVTISV 1424
Score = 32.3 bits (70), Expect = 9.9
Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Query: 497 WKEN-ISLSCNKVGVPAPATTWTMNGVGLESTL----RKNVSSD-GTLTISMTQSA--DS 548
W+ + L+C P P TW N ++ L + ++++ G L++ + + A DS
Sbjct: 166 WEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDS 225
Query: 549 GNYTCSVENIHGR 561
YT V+N HG+
Sbjct: 226 ATYTVRVKNAHGQ 238
>AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens
cDNA FLJ46367 fis, clone TESTI4051424, weakly similar
to M-protein, striated muscle. ).
Length = 1172
Score = 74.9 bits (176), Expect = 1e-12
Identities = 93/433 (21%), Positives = 180/433 (41%), Gaps = 48/433 (11%)
Query: 54 SKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE 112
+K+T+ + +P P N+ + + + ++W +P G +P+ + +
Sbjct: 220 NKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIGSG 279
Query: 113 SWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS-- 170
+W + + P +V +L+ SY R+ A N+ G S+PS+P + P+
Sbjct: 280 TWEAISSES--PVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATL 337
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
PP V+ + T + +TW+P + + +LGYY+ +++ ++ + + P
Sbjct: 338 PPPAQVQAFRDTQTSVSLTWDPVK----DPELLGYYIYSRKVGTSEWQTVNNKP------ 387
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMED---VPSLPP 287
++G +R T+ L+ Y V++ + ++ PS P
Sbjct: 388 ---IQG-----TRFTVPRLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPY 439
Query: 288 GALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY--APVTDWYG-NEDAVTKQISGLH 344
G N ++ V + W+PP RG IL GY + + DW+ N+ + ++
Sbjct: 440 GFALLNCGKNEMV-IGWKPPKRRGGGKIL-GYFLDQHDSEELDWHAVNQQPIPTRV---- 493
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSSRNKI 400
+S L Y A AG G +AP ++ P P D++A+ +
Sbjct: 494 CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSL 553
Query: 401 LVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS--H-ETSRSPPRATHQ 456
++ W PP G + GY ++S E+G E+ + ++P +S H S P ++
Sbjct: 554 VLQWEPPLYMGAGPVTGY--HVSFQEEGSEQW---KPVTPGPISGTHLRVSDLQPGKSYV 608
Query: 457 FWVSASTRLGEGE 469
F V A G G+
Sbjct: 609 FQVQAMNSAGLGQ 621
Score = 64.9 bits (151), Expect = 2e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 23/219 (10%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P P +++ + I W P G I+ Y + ++ E W + Q+ I P V
Sbjct: 435 PSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPI-PTRV 493
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPS-GPPQDVRVEAKSST 184
V +L Y R A N G E S P + +E +P GPP DVR +T
Sbjct: 494 --CKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRAT 551
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
L++ WEPP + G + GY+V FQE S + GP + G +
Sbjct: 552 SLVLQWEPPLY-MGAGPVTGYHVSFQEEGSEQWKPVTPGP---------ISG-----THL 596
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP 283
+S LQ +Y VQA NS +ED P
Sbjct: 597 RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKP 635
Score = 62.9 bits (146), Expect = 6e-09
Identities = 85/375 (22%), Positives = 145/375 (38%), Gaps = 36/375 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P N+R +D + ++W P +PI Y ++ + W + + PG
Sbjct: 108 PGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE---APGGT 164
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-----PQDVRVEAKS 182
++ L SY R+ A +R+G S PS+ ++ + + P D+ +
Sbjct: 165 CRCPIRGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITI 224
Query: 183 STELI---VTWEPPQRDLWNGNILGYYV--GFQELNSNS----TVLIASGPGGASYTVRT 233
ST+ VT P ++ I YV ++E + T + G S T
Sbjct: 225 STDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIG-SGTWEA 283
Query: 234 VEGAGTARS-RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL--PPGAL 290
+ RS R + L+K +Y V+A N + P+ PP +
Sbjct: 284 ISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQV 343
Query: 291 QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGLHTTLS 348
Q + SV ++W+P ++ L GY + V ++W + K I G T+
Sbjct: 344 QAFRDTQTSVSLTWDPV----KDPELLGYYIYSRKVGTSEW---QTVNNKPIQGTRFTVP 396
Query: 349 GLRRYTNYSVTVCAFTAAGDGVRAA---PVYCHTEEDVPSAPADIKAAVSSRNKILVSWL 405
LR Y V + + AG G +A P+ PSAP +N++++ W
Sbjct: 397 RLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWK 456
Query: 406 PPS-SPNGVLVGYTL 419
PP G ++GY L
Sbjct: 457 PPKRRGGGKILGYFL 471
Score = 57.6 bits (133), Expect = 2e-07
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 16/185 (8%)
Query: 487 TSFSRNIVTPWKENISLSC--NKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTIS 541
TS + + KE SLSC ++ + A + W +G L S+ R+ + +L +S
Sbjct: 9 TSVLKPVFAREKEPFSLSCLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVS 68
Query: 542 MTQSADSGNYTCSVENIHG-RDEVTYTV----EVKVPPQP--PI-LAVVDSYADSLHLQW 593
T D G YT V + G R++ TY + E + P P P+ + +D D L L W
Sbjct: 69 CTYKEDEGLYTVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTW 128
Query: 594 SDQGDG-GSPILGYVINY-KREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRI 650
+ D G+PI Y I + E G+W + GT + L G Y+ + A +R+
Sbjct: 129 APPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIRGLVEGQSYRFRVRAISRV 188
Query: 651 GTGLP 655
G+ +P
Sbjct: 189 GSSVP 193
Score = 56.0 bits (129), Expect = 7e-07
Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKE-APESW-PSTPQKVIVPGS 126
P P ++R + ++ ++ + W P Y G P+ Y V ++E E W P TP P S
Sbjct: 537 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPG----PIS 592
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T V +LQP SY ++ A N G +PS P E+ P +V V+ + +
Sbjct: 593 GTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEVGVDEEGF--I 650
Query: 187 IVTWEPPQ 194
+ +E P+
Sbjct: 651 YLAFEAPE 658
Score = 45.2 bits (102), Expect = 0.001
Identities = 88/393 (22%), Positives = 153/393 (38%), Gaps = 35/393 (8%)
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREE--GTHKRMLSP- 439
+PS P ++ A+ ++++W PS + Y+L SVI G E + + SP
Sbjct: 235 IPSPPTNVHASEIREAYVVLAWEEPSPRGRAPLTYSLEKSVIGSGTWEAISSESPVRSPR 294
Query: 440 -STLSHETSRS---PPRATHQFWVSASTRLGEGEATR--VVTVLPSDSVPA-RITSFSRN 492
+ L E +S RA +Q+ +S + E A R T+ P V A R T S +
Sbjct: 295 FAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVS 354
Query: 493 IV-TPWKENISLSCNKVGVPAPATTW-TMNGVGLESTL----RKNVSSDGTLTISMTQSA 546
+ P K+ L + W T+N ++ T R + + A
Sbjct: 355 LTWDPVKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPRLRTGKEYEFCVRSVSEA 414
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILG 605
G + + E I + + P P A+++ + + + W + GG ILG
Sbjct: 415 GVGESSAATEPIRVKQALA------TPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILG 468
Query: 606 YVIN-YKREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG---LPCDIVH 660
Y ++ + E DW + Q T + +L G Y+ A N G G P +
Sbjct: 469 YFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFE 528
Query: 661 AYTKGTVPV--KPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVS 717
+ T+P P + + T++ + W G + + + ++E QW+ V+
Sbjct: 529 C-KEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVT 587
Query: 718 -NSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ T VS L P Y ++ A N+AG
Sbjct: 588 PGPISGTH--LRVSDLQPGKSYVFQVQAMNSAG 618
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTKQISGL 343
PP ++ + + + S+ + WEPP G G + GY V++ W + ISG
Sbjct: 539 PPYDVRASEVRATSLVLQWEPPLYMGA-GPVTGYHVSFQEEGSEQW---KPVTPGPISGT 594
Query: 344 HTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
H +S L+ +Y V A +AG G + P ED P A +I+ V I ++
Sbjct: 595 HLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGA-HEIEVGVDEEGFIYLA 653
Query: 404 WLPPSSPN 411
+ P +P+
Sbjct: 654 FEAPEAPD 661
Score = 40.7 bits (91), Expect = 0.028
Identities = 112/548 (20%), Positives = 198/548 (36%), Gaps = 56/548 (10%)
Query: 152 GQSEPSQPVQVTTTE-EVPSGP--PQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVG 208
G E S V V E E P P P +VR + LI+TW PP D I Y +
Sbjct: 87 GPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPS-DTRGNPITAYTIE 145
Query: 209 FQELNSNSTVLIASGPGGASYT-VRTVEGAGTARSRTTL-----SGLQKHAAYAVVVQAY 262
+ S + PGG +R + + R R S + A+ VV+ +
Sbjct: 146 RCQGESGEWIACHEAPGGTCRCPIRGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDH 205
Query: 263 NSRXXXXXX-------XXXXXXXMEDVPSLP--PGALQCNALSSQSVRVSWEPPPMRGRN 313
++ ED ++P P + + + V ++WE P RGR
Sbjct: 206 DAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRGRA 265
Query: 314 GILQGYRVTYAPVTDWYGNEDAVTKQ--ISGLHTTLSGLRRYTNYSVTVCAFTAAG---D 368
+ + W +A++ + + + L + +Y V A G
Sbjct: 266 PLTYSLEKSVIGSGTW----EAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDP 321
Query: 369 GVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
+ P+ PA ++A ++ + ++W P P L+GY +Y +
Sbjct: 322 SEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPE--LLGYYIYSRKVGTSE 379
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEAT------RVVTVLPSDSV 482
+ + + + + + R+ ++F V + + G GE++ RV L + S
Sbjct: 380 WQTVNNKPIQGTRFTVPRLRTGKE--YEFCVRSVSEAGVGESSAATEPIRVKQALATPSA 437
Query: 483 P---ARITSFSRNIVTPWKENISLSCNKV-GV-----PAPATTW-TMNGVGLESTLRKNV 532
P A + +V WK K+ G + W +N + + + K
Sbjct: 438 PYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCK-- 495
Query: 533 SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP-PQPPI-LAVVDSYADSLH 590
SD A + N+ V + + E +P P PP + + A SL
Sbjct: 496 VSDLHEGHFYEFRARAANW-AGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLV 554
Query: 591 LQWSDQ-GDGGSPILGYVINYKREHGD-WEELQVEAGTSEHV-LPNLWCGTRYQLYITAF 647
LQW G P+ GY ++++ E + W+ + + H+ + +L G Y + A
Sbjct: 555 LQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLRVSDLQPGKSYVFQVQAM 614
Query: 648 NRIGTGLP 655
N G G P
Sbjct: 615 NSAGLGQP 622
Score = 35.9 bits (79), Expect = 0.80
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNV-SSDGTLTISMTQSADSGNYTCSV 555
+ + L+C G P P +W N V R V ++ T+TI S DSG Y V
Sbjct: 1085 KTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFV 1144
Query: 556 ENIHGRDEVTYTVEV 570
+N +G + T+ V
Sbjct: 1145 KNKYGSETGQVTISV 1159
>BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein C,
fast type protein.
Length = 1141
Score = 74.5 bits (175), Expect = 2e-12
Identities = 70/270 (25%), Positives = 105/270 (38%), Gaps = 14/270 (5%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-----LRKNVSSDGTLTISMTQSAD 547
IV + L + G P P TW +T + K V + I Q D
Sbjct: 554 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS-SFVIESAQRED 612
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYA-DSLHLQWS-DQGDGGSPILG 605
G YT V N G D + ++V P PP + S D L W DGG P+ G
Sbjct: 613 EGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTG 672
Query: 606 YVINYKREHGD-WEELQVEAGT-SEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y++ K++ W +L E T + + + G Y++ + A N IG P +
Sbjct: 673 YLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM 732
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
+P H + + TT T+ W G GI +++EY +W V + +
Sbjct: 733 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW--VPANTEP 790
Query: 723 TERV-FSVSGLTPAAHYQLRITAHNNAGHA 751
ER F+V L A R+ N AG +
Sbjct: 791 VERCGFTVKNLPTGARILFRVVGVNIAGRS 820
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 7/143 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKE-APESWPSTPQKVIVPGS 126
VP+ P+ +R+ + W P Y G P+ Y+V+ K+ + W +V
Sbjct: 638 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT--E 695
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T S + ++ Y +R+ A N +G S+PS + P+ P + VE + T
Sbjct: 696 TTYESTKMIE-GILYEMRVFAVNAIGVSQPSMNTK-PFMPIAPTSEPLHLIVEDVTDTTT 753
Query: 187 IVTWEPPQRDLWNGNILGYYVGF 209
+ W PP R + G I GY V +
Sbjct: 754 TLKWRPPNR-IGAGGIDGYLVEY 775
Score = 50.0 bits (114), Expect = 5e-05
Identities = 84/385 (21%), Positives = 138/385 (35%), Gaps = 22/385 (5%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVT 337
DVP PP A++ ++ + WEPP G + GY V W N + T
Sbjct: 637 DVPD-PPEAVRITSVGEDWAILVWEPPMYDGGKPVT-GYLVERKKKGSQRWMKLNFEVFT 694
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSR 397
+ + G+ Y + V A A G + S P + +
Sbjct: 695 ETTYESTKMIEGIL----YEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTD 750
Query: 398 NKILVSWLPPSSPN-GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQ 456
+ W PP+ G + GY + + +G EE P A
Sbjct: 751 TTTTLKWRPPNRIGAGGIDGYLVEYCL--EGSEEWVPANTEPVERCGFTVKNLPTGARIL 808
Query: 457 FWVSASTRLGEGEATRV---VTVLPSDSVPA-RITSFSRNI-VTPWKENISLSCNKVGVP 511
F V G E + VT+ P R+ R + E ++L G P
Sbjct: 809 FRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 868
Query: 512 APATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA--DSGNYTCSVENIHGRDEVTYTVE 569
P WT G L+++ +SD + Q+A DSG Y SV+ + +D T +
Sbjct: 869 RPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIR 928
Query: 570 VKVPPQPPI-LAVVDSYADSLHLQW-SDQGDGGSPILGYVI-NYKREHGDWEELQVEAGT 626
V PPI + V + + + ++W + + DG S I+GY + ++ +W +
Sbjct: 929 VVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRH 988
Query: 627 SEHVLPNLWCGTRYQLYITAFNRIG 651
+ + +L G Y + N G
Sbjct: 989 TSCTVSDLIVGNEYYFRVYTENICG 1013
Score = 38.3 bits (85), Expect = 0.15
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESW-PSTPQKVIVPGSVTS 129
P ++ V D T + W P G I Y+V+Y E E W P+ + V G
Sbjct: 740 PLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGF--- 796
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP 172
+V+NL R++ N G+SEP+ Q T E+ P
Sbjct: 797 -TVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPP 838
Score = 36.3 bits (80), Expect = 0.61
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTISMTQSA--DSGNYTCSVENI 558
+L+C G P P W N + + + +++ G LT+++ + + D+G YTC N
Sbjct: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNE 1125
Query: 559 HGRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1126 LGEALAECKLEVRVP 1140
Score = 33.5 bits (73), Expect = 4.3
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 170 SGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
+GPP +V V+ T +V W+ P+ D N I+GY+V
Sbjct: 933 AGPPINVMVKEVWGTNALVEWQAPKDD-GNSEIMGYFV 969
>X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.
Length = 1142
Score = 74.1 bits (174), Expect = 2e-12
Identities = 70/268 (26%), Positives = 104/268 (38%), Gaps = 14/268 (5%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-----LRKNVSSDGTLTISMTQSAD 547
IV + L + G P P TW +T + K V + I Q D
Sbjct: 555 IVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCS-SFVIESAQRED 613
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYA-DSLHLQWS-DQGDGGSPILG 605
G YT V N G D + ++V P PP + S D L W DGG P+ G
Sbjct: 614 EGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTG 673
Query: 606 YVINYKREHGD-WEELQVEAGT-SEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT 663
Y++ K++ W +L E T + + + G Y++ + A N IG P +
Sbjct: 674 YLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM 733
Query: 664 KGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQA 722
+P H + + TT T+ W G GI +++EY +W V + +
Sbjct: 734 PIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEW--VPANTEP 791
Query: 723 TERV-FSVSGLTPAAHYQLRITAHNNAG 749
ER F+V L A R+ N AG
Sbjct: 792 VERCGFTVKNLPTGARILFRVVGVNIAG 819
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 7/143 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKE-APESWPSTPQKVIVPGS 126
VP+ P+ +R+ + W P Y G P+ Y+V+ K+ + W +V
Sbjct: 639 VPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT--E 696
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
T S + ++ Y +R+ A N +G S+PS + P+ P + VE + T
Sbjct: 697 TTYESTKMIE-GILYEMRVFAVNAIGVSQPSMNTK-PFMPIAPTSEPLHLIVEDVTDTTT 754
Query: 187 IVTWEPPQRDLWNGNILGYYVGF 209
+ W PP R + G I GY V +
Sbjct: 755 TLKWRPPNR-IGAGGIDGYLVEY 776
Score = 49.6 bits (113), Expect = 6e-05
Identities = 39/158 (24%), Positives = 69/158 (43%), Gaps = 5/158 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSA--DSGNYTCSVE 556
E ++L G P P WT G L+++ +SD + Q+A DSG Y SV+
Sbjct: 857 EQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ 916
Query: 557 NIHGRDEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQW-SDQGDGGSPILGYVI-NYKRE 613
+ +D T + V PPI + V + + + ++W + + DG S I+GY + ++
Sbjct: 917 IENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKK 976
Query: 614 HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIG 651
+W + + + +L G Y + N G
Sbjct: 977 TMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICG 1014
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESW-PSTPQKVIVPGSVTS 129
P ++ V D T + W P G I Y+V+Y E E W P+ + V G
Sbjct: 741 PLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGF--- 797
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP 172
+V+NL R++ N G++EP+ Q T E+ P
Sbjct: 798 -TVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPP 839
Score = 36.3 bits (80), Expect = 0.61
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTISMTQSA--DSGNYTCSVENI 558
+L+C G P P W N + + + +++ G LT+++ + + D+G YTC N
Sbjct: 1067 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNE 1126
Query: 559 HGRDEVTYTVEVKVP 573
G +EV+VP
Sbjct: 1127 LGEALAECKLEVRVP 1141
Score = 33.5 bits (73), Expect = 4.3
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 170 SGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
+GPP +V V+ T +V W+ P+ D N I+GY+V
Sbjct: 934 AGPPINVMVKEVWGTNALVEWQAPKDD-GNSEIMGYFV 970
>L02870-1|AAA75438.1| 2944|Homo sapiens alpha-1 type VII collagen
protein.
Length = 2944
Score = 73.7 bits (173), Expect = 3e-12
Identities = 133/597 (22%), Positives = 230/597 (38%), Gaps = 73/597 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP---ESWPSTPQKVIVPGSVTS 129
P+++ + + S+++++ WT A + P+ Y VQY + PS Q+V VP TS
Sbjct: 235 PRDLVLSEPSSQSLRVQWT---AASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETS 291
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ L+P T Y + +IA L + + V T GP ++ ++ ++ L+V
Sbjct: 292 VRLRGLRPLTEYQVTVIA---LYANSIGEAVSGTARTTALEGP--ELTIQNTTAHSLLVA 346
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W GY V ++ L+ T GPG S +R +E GT
Sbjct: 347 WRSVP------GATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLE-PGT---------- 389
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
Y V V R +L P L S+ +SW P
Sbjct: 390 ----DYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-----VILGPTSILLSWNLVPE 440
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+GYR+ + T + V L GL+ T Y +T+ G
Sbjct: 441 ------ARGYRLEWRRETGLEPPQKVVLPS-DVTRYQLDGLQPGTEYRLTLYTL-LEGHE 492
Query: 370 VRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
V T ++P +P D++A ++ VSW P + G T Y ++
Sbjct: 493 VATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSP-------VPGATQYRIIVRS-- 543
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG--EGEATRVVTVLPSDSVPARI 486
+G + ++ P + + +A + V S R+G EG A+ V+TV P +
Sbjct: 544 TQGVERTLVLPGSQT-AFDLDDVQAGLSYTVRVSARVGPREGSAS-VLTVRREPETPLAV 601
Query: 487 TSFSRNIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
+V + ++ V G +W+ G G ES+ + + D T T +T
Sbjct: 602 PGL--RVVVSDATRVRVAWGPVPGASGFRISWS-TGSGPESS--QTLPPDSTAT-DITGL 655
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPI--LAVVDSYADSLHLQWSDQGDGGSP 602
Y +V + GR+E V V + P P+ + V + + S+ + W+ + G +
Sbjct: 656 QPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWT-RVPGAT- 713
Query: 603 ILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
GY +++ HG + V + L L T Y +++ A G P +V
Sbjct: 714 --GYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVV 768
Score = 57.2 bits (132), Expect = 3e-07
Identities = 133/548 (24%), Positives = 209/548 (38%), Gaps = 73/548 (13%)
Query: 70 PEMP----KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
PE+P +++ + + +++SW+ P G + QY+ S + +++PG
Sbjct: 504 PELPVSPVTDLQATELPGQRVRVSWS-PVPGAT-------QYRIIVRSTQGVERTLVLPG 555
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE-EVPSGPPQDVRVEAKSST 184
S T+ + ++Q SY +R+ A R+G E S V E E P P +RV +T
Sbjct: 556 SQTAFDLDDVQAGLSYTVRVSA--RVGPREGSASVLTVRREPETPLAVP-GLRVVVSDAT 612
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ V W P G+ + + ST SGP + +T+ TA T
Sbjct: 613 RVRVAWGPVP------GASGFRISW------ST---GSGPESS----QTLPPDSTA---T 650
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++GLQ Y V V R P P + SS SV ++W
Sbjct: 651 DITGLQPGTTYQVAVSVLRGREEGPAAVIVARTD----PLGPVRTVHVTQASSSSVTITW 706
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
P G GYRV++ +G E + L GL T Y+V V A
Sbjct: 707 TRVP--GAT----GYRVSWHSA---HGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHV 757
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
A DG A+ V T + + ++ +S + + ++W+ GV G T Y +
Sbjct: 758 AGVDGPPAS-VVVRTAPEPVGRVSRLQILNASSDVLRITWV------GV-TGATAYR--L 807
Query: 425 EDGREEGTHKR--MLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
GR EG R +L +T S E ++ V+A EG +V P ++
Sbjct: 808 AWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAP 867
Query: 483 PARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLES-TLRKNVSSDGTLTI 540
PA T ++V + ++ L V W G +S L +SS +
Sbjct: 868 PALGT---LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSS---YHL 921
Query: 541 SMTQSADSGNYTCSVENIHGR-DEVTYTVEVKVPPQPPI-LAVVDSYADSLHLQWSDQGD 598
+ A SV G T + P P I L VVD+ DS+ L W+
Sbjct: 922 DGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSR 981
Query: 599 GGSPILGY 606
S IL +
Sbjct: 982 ASSYILSW 989
Score = 55.6 bits (128), Expect = 9e-07
Identities = 90/387 (23%), Positives = 155/387 (40%), Gaps = 40/387 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
++P P LQ L Q VRVSW P P G Q YR+ V G E +
Sbjct: 505 ELPVSPVTDLQATELPGQRVRVSWSPVP-----GATQ-YRII---VRSTQGVERTLVLPG 555
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
S L ++ +Y+V V A +G A+ + E + P A ++ VS ++
Sbjct: 556 SQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGLRVVVSDATRV 614
Query: 401 LVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
V+W P +G + ++ G E + L P + + + + P T+Q V+
Sbjct: 615 RVAWGPVPGASGFRISWS-----TGSGPES---SQTLPPDSTATDITGLQPGTTYQ--VA 664
Query: 461 ASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWT 518
S G E V V +D + P R ++ +++++ +V G +W
Sbjct: 665 VSVLRGREEGPAAVIVARTDPLGPVRTV----HVTQASSSSVTITWTRVPGATGYRVSW- 719
Query: 519 MNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVE-NIHGRDEVTYTVEVKVPPQP- 576
+ G E + + VS + T+ D+ YT V ++ G D +V V+ P+P
Sbjct: 720 HSAHGPEKS--QLVSGEATVAELDGLEPDT-EYTVHVRAHVAGVDGPPASVVVRTAPEPV 776
Query: 577 ---PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LP 632
L ++++ +D L + W G + Y + + R G Q+ G ++ +
Sbjct: 777 GRVSRLQILNASSDVLRITWV----GVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIV 659
L G Y + +TA G P IV
Sbjct: 833 GLEGGVSYSVRVTALVGDREGTPVSIV 859
Score = 41.5 bits (93), Expect = 0.016
Identities = 107/469 (22%), Positives = 172/469 (36%), Gaps = 49/469 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVT----DWYGNEDAVTKQISG 342
P L + SSQS+RV W +G + GY+V Y P+T V
Sbjct: 235 PRDLVLSEPSSQSLRVQWT-----AASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGE 289
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
L GLR T Y VTV A A G + T + P ++ ++ + +LV
Sbjct: 290 TSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP----ELTIQNTTAHSLLV 345
Query: 403 SWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAS 462
+W S P GY + V+ G T ++ L P S P ++ V+ S
Sbjct: 346 AW--RSVPGA--TGYRVTWRVLSGG---PTQQQELGPGQGSVLLRDLEPGTDYE--VTVS 396
Query: 463 TRLGEGEATRVVTVLPSDSVPARITSFSRNIVTP---WKENISLSCNKVGVPAPATTWTM 519
T G +V P+ S+ AR + + P +I LS N V
Sbjct: 397 TLFGR-------SVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWR 449
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN-IHGRDEVTYTVEVKVPPQPPI 578
GLE + + SD T + Y ++ + G + T V P+ P+
Sbjct: 450 RETGLEPPQKVVLPSDVT-RYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPV 508
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILG---YVINYKREHGDWEELQVEAGTSEHVLPNLW 635
V D A L Q SP+ G Y I + G L + + L ++
Sbjct: 509 SPVTDLQATELPGQ--RVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQ 566
Query: 636 CGTRYQLYITAFNRIGTGL-PCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDG 694
G Y + ++A R+G ++ + P+ +++ + T V V +WG
Sbjct: 567 AGLSYTVRVSA--RVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRV---AWGPV 621
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
G F I + S P+ S ++ ++GL P YQ+ ++
Sbjct: 622 P-GASGFRISWSTGSGPE---SSQTLPPDSTATDITGLQPGTTYQVAVS 666
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 70 PEMPK-NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P +P +RV+D ++ ++WT +S I+++ + + P +PQ +PG +
Sbjct: 955 PRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSW-RPLRGPGQEVPGSPQ--TLPGISS 1011
Query: 129 SASVQNLQPATSY 141
S V L+P SY
Sbjct: 1012 SQRVTGLEPGVSY 1024
>U73778-1|AAC51244.1| 3063|Homo sapiens collagen type XII alpha-1
protein.
Length = 3063
Score = 72.9 bits (171), Expect = 6e-12
Identities = 107/445 (24%), Positives = 182/445 (40%), Gaps = 51/445 (11%)
Query: 58 VDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPST 117
++ + ++ + PK++ + S + +W+ AG + + +Y + YKEA T
Sbjct: 620 IEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSP--AGEN-VFSYHITYKEAAGDDEVT 676
Query: 118 PQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVR 177
V+ P S TS + +L+P T Y + + AE G S P + TTEEV G P++++
Sbjct: 677 ---VVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEE--TTEEV-KGAPRNLK 730
Query: 178 VEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGA 237
V +++ +TW G +L + ++ + GG S V T
Sbjct: 731 VTDETTDSFKITWTQAP-----GRVLRCRIIYRPV-----------AGGESREVTTPPN- 773
Query: 238 GTARSRTTLSGLQKHAAYAV-VVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALS 296
+ R TL L Y V V+ Y S E+V P L+ + +
Sbjct: 774 ---QRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAAT---EEVRGNPRD-LRVSDPT 826
Query: 297 SQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNY 356
+ ++++SW P G ++ Y VTY PV G VT + +T L GL+ T Y
Sbjct: 827 TSTMKLSWSGAP-----GKVKQYLVTYTPVAG--GETQEVTVRGDTTNTVLQGLKEGTQY 879
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVG 416
+++V A A+G G EE +P D+ + I W +S G++ G
Sbjct: 880 ALSVTALYASGAGDALFGEGTTLEE--RGSPQDLVTKDITDTSIGAYW---TSAPGMVRG 934
Query: 417 YTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATR--VV 474
Y + + D + G ++ L + P ++ V A+ GEGE
Sbjct: 935 YRVSWKSLYDDVDTG--EKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDAT 992
Query: 475 TVLPSDSVPARITSFSRNIV-TPWK 498
T L DS ++ + N + WK
Sbjct: 993 TELSQDSKTLKVDEETENTMRVTWK 1017
Score = 59.7 bits (138), Expect = 6e-08
Identities = 75/303 (24%), Positives = 122/303 (40%), Gaps = 41/303 (13%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++++ D T+ + W +P G + YIV+YK E ++V V S TS S+
Sbjct: 1569 PQDLKLRDVTHSTMNVFW-EPVPGK--VRKYIVRYKTPEED----VKEVEVDRSETSTSL 1621
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
++L T Y + + A + G+S P + TT VP+ P ++++ +S TW+
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQE--TTRPVPA--PTNLKITEVTSEGFRGTWDH 1677
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
D+ S I GP G+S + T+ + L +
Sbjct: 1678 GASDV------------------SLYRITWGPFGSSDKMETILNGD--ENTLVFENLNPN 1717
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXME----DVPSLPPGALQCNALSSQSVRVSWEPPP 308
Y V + A + + P P LQ +S S+ V W+P
Sbjct: 1718 TIYEVSITAIYADESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA- 1776
Query: 309 MRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
+G +Q YR+TY P T GNE T L L+ T Y++TV + G+
Sbjct: 1777 ----SGRVQKYRITYQPSTG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 369 GVR 371
G R
Sbjct: 1832 GGR 1834
Score = 58.0 bits (134), Expect = 2e-07
Identities = 77/291 (26%), Positives = 119/291 (40%), Gaps = 40/291 (13%)
Query: 72 MPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSAS 131
+ +N++V + + + W P G P++ Y V Y + PS + ++VPG+
Sbjct: 1936 LARNVQVYNPTPNRLGVRW-DPAPG--PVLQYRVVYSPVDGTRPS--ESIVVPGNTRMVH 1990
Query: 132 VQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWE 191
++ L P T Y + ++A G+ PS P Q T +P P+++RV +++ L V W
Sbjct: 1991 LERLIPDTLYSVNLVALYSDGEGNPS-PAQGRT---LPRSGPRNLRVFGETTNSLSVAW- 2045
Query: 192 PPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQK 251
D +G + Y + + + TV G YT TV G R+ L LQ
Sbjct: 2046 ----DHADGPVQQYRIIY-----SPTV----GDPIDEYT--TVPG---RRNNVILQPLQP 2087
Query: 252 HAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRG 311
Y + V A V LPP + + RVSW+P P
Sbjct: 2088 DTPYKITVIAVYEDGDGGHLTGNG----RTVGLLPPQNIHISDEWYTRFRVSWDPSP--- 2140
Query: 312 RNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
+ +L GY++ Y PV E V + S TL L T Y V V A
Sbjct: 2141 -SPVL-GYKIVYKPVGSNEPMEAFVGEMTS---YTLHNLNPSTTYDVNVYA 2186
Score = 56.4 bits (130), Expect = 5e-07
Identities = 85/368 (23%), Positives = 151/368 (41%), Gaps = 57/368 (15%)
Query: 75 NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQN 134
++ + D T+ + W QP G + YI+ YK ++ P+ P++V + +V + +
Sbjct: 1479 SLNIYDVGPTTMHVQW-QPVGGAT---GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 1534
Query: 135 LQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQ 194
L P T Y + + A SEP +VT +P PQD+++ + + + V WEP
Sbjct: 1535 LVPNTEYAVTVQAVLHDLTSEPVTVREVT----LPLPRPQDLKLRDVTHSTMNVFWEPVP 1590
Query: 195 RDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAA 254
G + Y V ++ + V+ VE + + T+L L
Sbjct: 1591 -----GKVRKYIVRYKTPEED---------------VKEVE-VDRSETSTSLKDLFSQTL 1629
Query: 255 YAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNG 314
Y V V A + VP+ P L+ ++S+ R +W+ G +
Sbjct: 1630 YTVSVSAVHDEGESPPVTAQETT--RPVPA--PTNLKITEVTSEGFRGTWD----HGASD 1681
Query: 315 ILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL--SGLRRYTNYSVTVCAFTA---AGDG 369
+ YR+T+ P +G+ D + ++G TL L T Y V++ A A D
Sbjct: 1682 V-SLYRITWGP----FGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYADESESDD 1736
Query: 370 V----RAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL-YMSVI 424
+ R P+ T + S P +++ ++ N + V W P S G + Y + Y
Sbjct: 1737 LIGSERTLPIL--TTQAPKSGPRNLQVYNATSNSLTVKWDPAS---GRVQKYRITYQPST 1791
Query: 425 EDGREEGT 432
+G E+ T
Sbjct: 1792 GEGNEQTT 1799
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/147 (25%), Positives = 72/147 (48%), Gaps = 14/147 (9%)
Query: 63 GSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
G + ++ + K ++V ++ T++++W +P G ++NY V Y+ +
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK--VVNYRVVYRPHGRGKQMVAK--- 1042
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
VP +VTS ++ LQP T+Y + ++ ++G+ + Q TT S P++++ +
Sbjct: 1043 VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQG-SGTTASRFKS--PRNLKTSDPT 1099
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGF 209
+ VTWEP G + GY V F
Sbjct: 1100 MSSFRVTWEPAP-----GEVKGYKVTF 1121
Score = 45.6 bits (103), Expect = 0.001
Identities = 131/597 (21%), Positives = 225/597 (37%), Gaps = 74/597 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
E P N+ + ++ R+ ++SWT P + + Y V+Y P S Q+ V TS
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPP---SDSVDRYKVEY--YPVS-GGKRQEFYVSRMETST 1439
Query: 131 SVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTW 190
+++L+P T Y + + + + + E S+P++ TE+ P + + T + V W
Sbjct: 1440 VLKDLKPETEYVVNVYS---VVEDEYSEPLK--GTEKTLPVPVVSLNIYDVGPTTMHVQW 1494
Query: 191 EPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
+P G GY + ++ + VR G + L+ L
Sbjct: 1495 QPV------GGATGYILSYKPVKDTEPT--------RPKEVR----LGPTVNDMQLTDLV 1536
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
+ YAV VQA +P P L+ ++ ++ V WEP P +
Sbjct: 1537 PNTEYAVTVQA----VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK 1592
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGV 370
R I++ Y+ V + V S T+L L T Y+V+V A G+
Sbjct: 1593 VRKYIVR-YKTPEEDVKE-------VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE-- 1642
Query: 371 RAAPVYC-HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVL------VGYTLYMSV 423
+ PV T VP AP ++K + +W +S + G + M
Sbjct: 1643 -SPPVTAQETTRPVP-APTNLKITEVTSEGFRGTWDHGASDVSLYRITWGPFGSSDKMET 1700
Query: 424 IEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVP 483
I +G E L+P+T+ +E S + A + +G ++T S P
Sbjct: 1701 ILNGDENTLVFENLNPNTI-YEVSITAIYADES---ESDDLIGSERTLPILTTQAPKSGP 1756
Query: 484 ARITSF---SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTI 540
+ + S ++ W + S K + +T G G E T + +
Sbjct: 1757 RNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPST----GEGNEQT--TTIGGRQNSVV 1809
Query: 541 SMTQSADSGNYTCSVENIHGRDE-VTYTVEVKVPPQPPI--LAVVDSYADSLHLQWSDQG 597
D+ YT +V +++ E T K P + L V D +L+++W D
Sbjct: 1810 LQKLKPDT-PYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW-DHA 1867
Query: 598 DGGSPILGYVINYKREHGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
+G Y + Y G EEL + T+ +L NL T Y + + G G
Sbjct: 1868 EGNP--RQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDG 1922
Score = 45.2 bits (102), Expect = 0.001
Identities = 66/296 (22%), Positives = 110/296 (37%), Gaps = 38/296 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+++ D +I WT + + Y V +K + T +K + P +
Sbjct: 908 PQDLVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDD-VDTGEKNL-PEDAIHTMI 962
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP T Y + + A G+ E P+ T E+ S + ++V+ ++ + VTW+P
Sbjct: 963 ENLQPETKYRISVFATYSSGEGE---PLTGDATTEL-SQDSKTLKVDEETENTMRVTWKP 1018
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G ++ Y V ++ + ++A P + TV L LQ
Sbjct: 1019 AP-----GKVVNYRVVYRP-HGRGKQMVAKVPPTVTSTV--------------LKRLQPQ 1058
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y + V P L+ + + S RV+WEP P
Sbjct: 1059 TTYDITVLPIYKMGEGKLRQGSGTTASR---FKSPRNLKTSDPTMSSFRVTWEPAP---- 1111
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGD 368
G ++GY+VT+ P D + V L LR T Y V V G+
Sbjct: 1112 -GEVKGYKVTFHPTGDDRRLGELVVGPYDNT-VVLEELRAGTTYKVNVFGMFDGGE 1165
Score = 44.4 bits (100), Expect = 0.002
Identities = 77/342 (22%), Positives = 132/342 (38%), Gaps = 45/342 (13%)
Query: 65 LSHQVPEM-PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIV 123
L+ Q P+ P+N++V + S ++ + W P +G + Y + Y+ P + Q +
Sbjct: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGR--VQKYRITYQ--PSTGEGNEQTTTI 1801
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSS 183
G S +Q L+P T Y I + E + T+ P +++RV S+
Sbjct: 1802 GGRQNSVVLQKLKPDTPY--TITVSSLYPDGEGGRMTGRGKTK--PLNTVRNLRVYDPST 1857
Query: 184 TELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSR 243
+ L V W+ + GN Y + + L+ PG +Y +
Sbjct: 1858 STLNVRWDHAE-----GNPRQYKLFYAPAAGGPEELVPI-PGNTNYAI------------ 1899
Query: 244 TTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVS 303
L LQ +Y V V + M + +Q + + V
Sbjct: 1900 --LRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR----NVQVYNPTPNRLGVR 1953
Query: 304 WEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAF 363
W+P P +LQ YRV Y+PV +E V + + L L T YSV + A
Sbjct: 1954 WDPAP----GPVLQ-YRVVYSPVDGTRPSESIVVPGNTRM-VHLERLIPDTLYSVNLVAL 2007
Query: 364 TAAGDGVRAAPVYCHTEEDVP-SAPADIKAAVSSRNKILVSW 404
+ G+G +P T +P S P +++ + N + V+W
Sbjct: 2008 YSDGEG-NPSPAQGRT---LPRSGPRNLRVFGETTNSLSVAW 2045
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P+NI + D+ ++SW SP++ Y + YK + P + V G +TS ++
Sbjct: 2119 PQNIHISDEWYTRFRVSWDP---SPSPVLGYKIVYKPVGSN---EPMEAFV-GEMTSYTL 2171
Query: 133 QNLQPATSYHLRIIAENRLGQSEP 156
NL P+T+Y + + A+ G S P
Sbjct: 2172 HNLNPSTTYDVNVYAQYDSGLSVP 2195
Score = 43.6 bits (98), Expect = 0.004
Identities = 81/380 (21%), Positives = 142/380 (37%), Gaps = 35/380 (9%)
Query: 285 LPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLH 344
+PP L + ++S + +W P G N + Y +TY +E V + S
Sbjct: 633 VPPKDLSFSEVTSYGFKTNWSPA---GEN--VFSYHITYKEAAG--DDEVTVVEPASSTS 685
Query: 345 TTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
LS L+ T Y V V A G + A T E+V AP ++K + + ++W
Sbjct: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGE--ETTEEVKGAPRNLKVTDETTDSFKITW 743
Query: 405 LPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTR 464
+P VL +Y V G + + +P T + T ++ VS
Sbjct: 744 --TQAPGRVLRCRIIYRPV-----AGGESREVTTPPNQRRRTLENLIPDT-KYEVSVIPE 795
Query: 465 LGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
G T + ++ V R + P + LS + G P + + +
Sbjct: 796 YFSGPGTPLTGNAATEEV--RGNPRDLRVSDPTTSTMKLSWS--GAPGKVKQYLVTYTPV 851
Query: 525 ESTLRKNVSSDGTLTISMTQSADSG-NYTCSVENIH--GRDEVTY----TVEVKVPPQPP 577
+ V+ G T ++ Q G Y SV ++ G + + T+E + PQ
Sbjct: 852 AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD- 910
Query: 578 ILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWE--ELQVEAGTSEHVLPNLW 635
L D S+ W+ + GY +++K + D + E + ++ NL
Sbjct: 911 -LVTKDITDTSIGAYWT---SAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQ 966
Query: 636 CGTRYQLYITAFNRIGTGLP 655
T+Y++ + A G G P
Sbjct: 967 PETKYRISVFATYSSGEGEP 986
Score = 41.1 bits (92), Expect = 0.021
Identities = 32/127 (25%), Positives = 60/127 (47%), Gaps = 10/127 (7%)
Query: 567 TVEVKV-PPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYK-REHGDWEELQVEA 624
++E +V PP ++D +++H+ W++ D PI+GY I G +E + A
Sbjct: 20 SIEAEVDPPSDLNFKIIDE--NTVHMSWAEPVD---PIVGYRITVDPTTDGPTKEFTLSA 74
Query: 625 GTSEHVLPNLWCGTRYQLYITAFNRIGTGLPC--DIVHAYTKGTVPVKPKHSQMITLNTT 682
T+E +L L T Y + IT+++ + +P + T PV+ K + +
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGK-TEIQKC 133
Query: 683 TVTVWLD 689
+V+ W D
Sbjct: 134 SVSAWTD 140
Score = 40.7 bits (91), Expect = 0.028
Identities = 81/347 (23%), Positives = 135/347 (38%), Gaps = 47/347 (13%)
Query: 74 KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVI-VPGSVTSASV 132
+N+RV D + T+ + W +A +P QYK P++++ +PG+ A +
Sbjct: 1848 RNLRVYDPSTSTLNVRWD--HAEGNPR-----QYKLFYAPAAGGPEELVPIPGNTNYAIL 1900
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+NLQP TSY + ++ G + T + G ++V+V + L V W+P
Sbjct: 1901 RNLQPDTSYTVTVVPVYTEGDGGRTS----DTGRTLMRGLARNVQVYNPTPNRLGVRWDP 1956
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
G +L Y V + ++ PG R V L L
Sbjct: 1957 AP-----GPVLQYRVVYSPVDGTRPSESIVVPG----NTRMVH----------LERLIPD 1997
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y+V + A S +P P L+ ++ S+ V+W+
Sbjct: 1998 TLYSVNLVALYSDGEGNPSPAQG----RTLPRSGPRNLRVFGETTNSLSVAWD-----HA 2048
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRA 372
+G +Q YR+ Y+P T ++ T + L L+ T Y +TV A GDG
Sbjct: 2049 DGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHL 2107
Query: 373 APVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
T +P P +I + + VSW P SP ++GY +
Sbjct: 2108 TG-NGRTVGLLP--PQNIHISDEWYTRFRVSWDPSPSP---VLGYKI 2148
Score = 38.3 bits (85), Expect = 0.15
Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 58 VDLRIGSL--SHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWP 115
VD ++G L +V E P N+ ++ S+ ++++W SP+ Y V P +
Sbjct: 320 VDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP---SPSPVTGYKVIL--TPMTAG 374
Query: 116 STPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQD 175
S + V T+ SV++L T Y + + A + SEP ++ T +V +
Sbjct: 375 SRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRG 434
Query: 176 VRVEA 180
V ++A
Sbjct: 435 VDIKA 439
Score = 37.1 bits (82), Expect = 0.35
Identities = 46/224 (20%), Positives = 86/224 (38%), Gaps = 15/224 (6%)
Query: 525 ESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENI-HGRDEVTYTV-EVKVP-PQPPILA 580
E T K V T+ + +T + Y +V+ + H TV EV +P P+P L
Sbjct: 1514 EPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLK 1573
Query: 581 VVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRY 640
+ D ++++ W + Y++ YK D +E++V+ + L +L+ T Y
Sbjct: 1574 LRDVTHSTMNVFWEPVP---GKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLY 1630
Query: 641 QLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILY 700
+ ++A + G P + T VP + + T + +W G +
Sbjct: 1631 TVSVSAVHDEGESPP--VTAQETTRPVPAPTN----LKITEVTSEGFRGTWDHGASDVSL 1684
Query: 701 FVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ I + + + E L P Y++ ITA
Sbjct: 1685 YRITWGPFGSSD--KMETILNGDENTLVFENLNPNTIYEVSITA 1726
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 72.9 bits (171), Expect = 6e-12
Identities = 39/125 (31%), Positives = 65/125 (52%), Gaps = 2/125 (1%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
VP P ++ + DQ +++Q+SWT NSPI +I++Y++A + V G+ T
Sbjct: 630 VPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 689
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
+A ++ L P +Y R++A N +G+S PS+ Q T P P V L+
Sbjct: 690 TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 748
Query: 188 VTWEP 192
+TW+P
Sbjct: 749 ITWKP 753
Score = 59.3 bits (137), Expect = 8e-08
Identities = 45/159 (28%), Positives = 61/159 (38%), Gaps = 6/159 (3%)
Query: 517 WTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQP 576
W + L S R V D L ++ DSG YTC + + V P P
Sbjct: 575 WLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNP 633
Query: 577 PI-LAVVDSYADSLHLQWSDQGDGGSPILGYVINYK---REHGDWEELQVEAGTSEHVLP 632
P L + D S+ L W+ D SPI ++I Y+ + G W +GT
Sbjct: 634 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL 693
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAY-TKGTVPVK 670
L Y + A N IG LP + Y TK + P K
Sbjct: 694 KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDK 732
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+SL C G+P P W L + + TL I ADSGNY C +N G
Sbjct: 282 LSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALG 341
Query: 561 RDEVTYTVEVKVPP 574
T +V VK P
Sbjct: 342 AIHHTISVRVKAAP 355
Score = 37.1 bits (82), Expect = 0.35
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 11/111 (9%)
Query: 477 LPSDSV-PARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKN 531
+P D V P IT S ++ + +ENI + C G P P+ +WT NG + L
Sbjct: 32 VPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
Query: 532 VSSDGTLTISMTQSADS----GNYTCSVENIHGRDEVTYTVEVKVPPQPPI 578
GTL I++ + G Y C+ N G V+ + V+ P + P+
Sbjct: 92 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGA-AVSNNIVVR-PSRSPL 140
Score = 37.1 bits (82), Expect = 0.35
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGT 537
+ P IT+ +++P ++ +L C G P P +W NGV +E + + D T
Sbjct: 353 AAPYWITAPQNLVLSPGEDG-TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-T 410
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
+ S Q S Y C+ N +G V V P P IL
Sbjct: 411 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP-PRIL 451
Score = 35.9 bits (79), Expect = 0.80
Identities = 57/257 (22%), Positives = 92/257 (35%), Gaps = 16/257 (6%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDGTLTISMTQSADSGNYTCSVENIH 559
L C G P P W G S L +++ +GTL I + Q +G YTC N
Sbjct: 468 LDCAFFGSPLPTIEWFKGAKG--SALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
Query: 560 GRDEVTYTVEVKVPP---QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGD 616
G + +E+K + P AVV + + + D + + RE
Sbjct: 526 GMAKNEVHLEIKDATWIVKQPEYAVVQR-GSMVSFECKVKHDHTLSLTVLWLKDNRELPS 584
Query: 617 WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQM 676
E V+ +H++ Y N + V + VP P ++
Sbjct: 585 DERFTVD---KDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVV--DVPNPPFDLEL 639
Query: 677 ITLNTTTVTVWLDSWGDGGCGILYFVIEYRE-MSQPQWRLVSNSVQATERVFSVSGLTPA 735
+V + D I F+IEY + M +P V T+ + L+P
Sbjct: 640 TDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLK-LSPY 698
Query: 736 AHYQLRITAHNNAGHAL 752
+Y R+ A N+ G +L
Sbjct: 699 VNYSFRVMAVNSIGKSL 715
>L23982-1|AAA58965.1| 2912|Homo sapiens collagen type VII protein.
Length = 2912
Score = 72.5 bits (170), Expect = 8e-12
Identities = 133/597 (22%), Positives = 230/597 (38%), Gaps = 73/597 (12%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAP---ESWPSTPQKVIVPGSVTS 129
P+++ + + S+++++ WT A + P+ Y VQY + PS Q+V VP TS
Sbjct: 235 PRDLVLSEPSSQSLRVQWT---AASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETS 291
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ L+P T Y + +IA L + + V T GP ++ ++ ++ L+V
Sbjct: 292 VRLRGLRPLTEYQVTVIA---LYANSIGEAVSGTARTTALEGP--ELTIQNTTAHSLLVA 346
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W GY V ++ L+ T GPG S +R +E GT
Sbjct: 347 WRSVP------GATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLE-PGT---------- 389
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
Y V V R +L P L S+ +SW P
Sbjct: 390 ----DYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-----VILGPTSILLSWNLVPE 440
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
+GYR+ + T + V L GL+ T Y +T+ G
Sbjct: 441 ------ARGYRLEWRRETGLEPPQKVVLPS-DVTRYQLDGLQPGTEYRLTLYTL-LEGHE 492
Query: 370 VRAAPVYCHTEEDVPSAP-ADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR 428
V T ++P +P D++A ++ VSW P + G T Y ++
Sbjct: 493 VATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSP-------VPGATQYRIIVRS-- 543
Query: 429 EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLG--EGEATRVVTVLPSDSVPARI 486
+G + ++ P + + +A + V S R+G EG A+ V+TV P +
Sbjct: 544 TQGVERTLVLPGSQT-AFDLDDVQAGLSYTVRVSARVGPREGSAS-VLTVRRELETPLAV 601
Query: 487 TSFSRNIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQS 545
+V + ++ V G +W+ G G ES+ + + D T T +T
Sbjct: 602 PGL--RVVVSDATRVRVAWGPVPGASGFRISWS-TGSGPESS--QTLPPDSTAT-DITGL 655
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEV-KVPPQPPI--LAVVDSYADSLHLQWSDQGDGGSP 602
Y +V + GR+E V V + P P+ + V + + S+ + W+ + G +
Sbjct: 656 QPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWT-RVPGAT- 713
Query: 603 ILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIV 659
GY +++ HG + V + L L T Y +++ A G P +V
Sbjct: 714 --GYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVV 768
Score = 56.4 bits (130), Expect = 5e-07
Identities = 104/422 (24%), Positives = 166/422 (39%), Gaps = 63/422 (14%)
Query: 70 PEMP----KNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG 125
PE+P +++ + + +++SW+ P G + QY+ S + +++PG
Sbjct: 504 PELPVSPVTDLQATELPGQRVRVSWS-PVPGAT-------QYRIIVRSTQGVERTLVLPG 555
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE-EVPSGPPQDVRVEAKSST 184
S T+ + ++Q SY +R+ A R+G E S V E E P P +RV +T
Sbjct: 556 SQTAFDLDDVQAGLSYTVRVSA--RVGPREGSASVLTVRRELETPLAVP-GLRVVVSDAT 612
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
+ V W P G+ + + ST SGP + +T+ TA T
Sbjct: 613 RVRVAWGPVP------GASGFRISW------ST---GSGPESS----QTLPPDSTA---T 650
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
++GLQ Y V V R P P + SS SV ++W
Sbjct: 651 DITGLQPGTTYQVAVSVLRGREEGPAAVIVARTD----PLGPVRTVHVTQASSSSVTITW 706
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFT 364
P G GYRV++ +G E + L GL T Y+V V A
Sbjct: 707 TRVP--GAT----GYRVSWHSA---HGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHV 757
Query: 365 AAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI 424
A DG A+ V T + + ++ +S + + ++W+ GV G T Y +
Sbjct: 758 AGVDGPPAS-VVVRTAPEPVGRVSRLQILNASSDVLRITWV------GV-TGATAYR--L 807
Query: 425 EDGREEGTHKR--MLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
GR EG R +L +T S E ++ V+A EG +V P ++
Sbjct: 808 AWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAP 867
Query: 483 PA 484
PA
Sbjct: 868 PA 869
Score = 55.6 bits (128), Expect = 9e-07
Identities = 107/479 (22%), Positives = 192/479 (40%), Gaps = 52/479 (10%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI 340
++P P LQ L Q VRVSW P P G Q YR+ V G E +
Sbjct: 505 ELPVSPVTDLQATELPGQRVRVSWSPVP-----GATQ-YRII---VRSTQGVERTLVLPG 555
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKI 400
S L ++ +Y+V V A +G A+ + E + P A ++ VS ++
Sbjct: 556 SQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRRELETPLAVPGLRVVVSDATRV 614
Query: 401 LVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVS 460
V+W P +G + ++ G E + L P + + + + P T+Q V+
Sbjct: 615 RVAWGPVPGASGFRISWS-----TGSGPES---SQTLPPDSTATDITGLQPGTTYQ--VA 664
Query: 461 ASTRLGEGEATRVVTVLPSDSV-PARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWT 518
S G E V V +D + P R ++ +++++ +V G +W
Sbjct: 665 VSVLRGREEGPAAVIVARTDPLGPVRTV----HVTQASSSSVTITWTRVPGATGYRVSW- 719
Query: 519 MNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVE-NIHGRDEVTYTVEVKVPPQP- 576
+ G E + + VS + T+ D+ YT V ++ G D +V V+ P+P
Sbjct: 720 HSAHGPEKS--QLVSGEATVAELDGLEPDT-EYTVHVRAHVAGVDGPPASVVVRTAPEPV 776
Query: 577 ---PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LP 632
L ++++ +D L + W G + Y + + R G Q+ G ++ +
Sbjct: 777 GRVSRLQILNASSDVLRITWV----GVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832
Query: 633 NLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSW 691
L G Y + +TA G P IV T P ++ ++ + W
Sbjct: 833 GLEGGVSYSVRVTALVGDREGTPVSIV-VTTPPEAPPALGTLHVVQRGEHSLRLRWEPVP 891
Query: 692 GDGGCGILYFVIEYR-EMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+ G F++ ++ E Q Q R++ + + + + GL PA Y++R++ AG
Sbjct: 892 REQG-----FLLHWQPEGGQEQSRVLGPELSS----YHLDGLEPATQYRVRLSVLGPAG 941
Score = 48.4 bits (110), Expect = 1e-04
Identities = 90/417 (21%), Positives = 149/417 (35%), Gaps = 53/417 (12%)
Query: 68 QVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
+ P +RV+ + ++++W P G S + + + S P + Q + P
Sbjct: 596 ETPLAVPGLRVVVSDATRVRVAWG-PVPGAS---GFRISWSTG--SGPESSQTL--PPDS 647
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T+ + LQP T+Y + + G+ E V V T+ P GP + V V SS+ +
Sbjct: 648 TATDITGLQPGTTYQVAVSVLR--GREEGPAAVIVARTD--PLGPVRTVHVTQASSSSVT 703
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+TW GY V + A GP + + V G T L
Sbjct: 704 ITWTRVP------GATGYRVSWHS---------AHGPEKS----QLVSGEATV---AELD 741
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
GL+ Y V V+A+ + E V + LQ SS +R++W
Sbjct: 742 GLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRV--SRLQILNASSDVLRITWV-- 797
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
G G YR+ + + + GL +YSV V A
Sbjct: 798 ---GVTG-ATAYRLAWGRSEGGPMRHQILPGNTDS--AEIRGLEGGVSYSVRVTALVGDR 851
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDG 427
+G + + T + P A + + + + W P G L+ + E G
Sbjct: 852 EGTPVS-IVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPREQGFLLHWQ-----PEGG 905
Query: 428 REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPA 484
+E+ R+L P S+ P ++ +S GEG + V S VP+
Sbjct: 906 QEQ---SRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959
Score = 40.7 bits (91), Expect = 0.028
Identities = 107/469 (22%), Positives = 172/469 (36%), Gaps = 49/469 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVT----DWYGNEDAVTKQISG 342
P L + SSQS+RV W +G + GY+V Y P+T V
Sbjct: 235 PRDLVLSEPSSQSLRVQWT-----AASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGE 289
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILV 402
L GLR T Y VTV A A G + T + P ++ ++ + +LV
Sbjct: 290 TSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP----ELTIQNTTAHSLLV 345
Query: 403 SWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAS 462
+W S P GY + V+ G T ++ L P S P ++ V+ S
Sbjct: 346 AW--RSVPGA--TGYRVTWRVLSGG---PTQQQELGPGQGSVLLRDLEPGTDYE--VTVS 396
Query: 463 TRLGEGEATRVVTVLPSDSVPARITSFSRNIVTP---WKENISLSCNKVGVPAPATTWTM 519
T G +V P+ S+ AR + + P +I LS N V
Sbjct: 397 TLFGR-------SVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWR 449
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVEN-IHGRDEVTYTVEVKVPPQPPI 578
GLE + + SD T + Y ++ + G + T V P+ P+
Sbjct: 450 RETGLEPPQKVVLPSDVT-RYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPV 508
Query: 579 LAVVDSYADSLHLQWSDQGDGGSPILG---YVINYKREHGDWEELQVEAGTSEHVLPNLW 635
V D A L Q SP+ G Y I + G L + + L ++
Sbjct: 509 SPVTDLQATELPGQ--RVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQ 566
Query: 636 CGTRYQLYITAFNRIGTGL-PCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDG 694
G Y + ++A R+G ++ + P+ +++ + T V V +WG
Sbjct: 567 AGLSYTVRVSA--RVGPREGSASVLTVRRELETPLAVPGLRVVVSDATRVRV---AWGPV 621
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRIT 743
G F I + S P+ S ++ ++GL P YQ+ ++
Sbjct: 622 P-GASGFRISWSTGSGPE---SSQTLPPDSTATDITGLQPGTTYQVAVS 666
Score = 35.5 bits (78), Expect = 1.1
Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 119 QKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
Q ++ ++S + L+PAT Y +R+ + LG + +VT E P P ++RV
Sbjct: 908 QSRVLGPELSSYHLDGLEPATQYRVRL---SVLGPAGEGPSAEVTARTESPRVPSIELRV 964
Query: 179 EAKSSTELIVTWEPPQR 195
S + + W P R
Sbjct: 965 VDTSIDSVTLAWTPVSR 981
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 70 PEMPK-NIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P +P +RV+D ++ ++WT +S I+++ + + P +PQ +PG +
Sbjct: 955 PRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSW-RPLRGPGQEVPGSPQ--TLPGISS 1011
Query: 129 SASVQNLQPATSY 141
S V L+P SY
Sbjct: 1012 SQRVTGLEPGVSY 1024
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 71.3 bits (167), Expect = 2e-11
Identities = 64/279 (22%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 494 VTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMTQSAD 547
V W+ N ++++C P+ +W +G L S+ N+ T L ++ D
Sbjct: 414 VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 473
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGY 606
GNY C+ N G++ + + + P P + V+ Y+ + +Q+ + + GG PIL Y
Sbjct: 474 FGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKY 533
Query: 607 VINYKRE-----HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
++ H W + + + + L T Y + + A N G G +I A
Sbjct: 534 KAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLG---EISAA 590
Query: 662 YTKGTVPVK-----PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
T PV+ PK + + ++ V L DGG I ++++ YR +S +W+
Sbjct: 591 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSS-EWKPE 649
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
++ V + L A Y++ + A N G + A +
Sbjct: 650 IRLPSGSDHVM-LKSLDWNAEYEVYVVAENQQGKSKAAH 687
Score = 59.3 bits (137), Expect = 8e-08
Identities = 78/348 (22%), Positives = 139/348 (39%), Gaps = 28/348 (8%)
Query: 421 MSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
MS +DG +EE K + S + + ++ A + GE +AT + V
Sbjct: 245 MSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW---TMNGVGLESTLRKNV- 532
+IT +E ++L+C G P P+ TW T N E TL ++
Sbjct: 305 FAKP----KITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 360
Query: 533 ----SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP--QPPILAVVDSYA 586
+ +LT+ Q D+G Y C+ N G+D + +EV+ P Q P+ AV
Sbjct: 361 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV-AVYTWEG 419
Query: 587 DSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV-EAGTSEHVLPNLWCGTRYQLY-I 644
+ +++ + I + ++ +++ ++ ++ + Y
Sbjct: 420 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 479
Query: 645 TAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
TA NRIG L +V A T P P Q+ ++T + + GG IL +
Sbjct: 480 TAVNRIGQESLEFILVQADT----PSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKA 535
Query: 704 EYREMSQPQW--RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
E+R + + W + + E + ++ GL P Y +R+ A N G
Sbjct: 536 EWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 583
Score = 46.0 bits (104), Expect = 7e-04
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 10/124 (8%)
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRK 530
+V V P+ I + + N+ ++++L C+ G P P +WT +G + E K
Sbjct: 207 IVNVPPTIQARQNIVNATANL----GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEK 262
Query: 531 NVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
+ SD + LTI D Y C EN G + T+ +KV +P I V + A
Sbjct: 263 YIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA--TIHLKVFAKPKITYVENQTAME 320
Query: 589 LHLQ 592
L Q
Sbjct: 321 LEEQ 324
Score = 41.5 bits (93), Expect = 0.016
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P PK + + +I+++ + G SPI +Y+V+Y+ W ++ +P
Sbjct: 602 PSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEW---KPEIRLPSGSDH 658
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++L Y + ++AEN+ G+S+ + V T+ + P+ P + + ST IV
Sbjct: 659 VMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQ--PTAIPANGSPTSGLSTGAIV 715
Score = 36.3 bits (80), Expect = 0.61
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P +I ++ S T Q+ + +P A G PI+ Y +++ E W S
Sbjct: 500 PSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 558
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--TEEVPSGP 172
++ L+P T+Y +R+ A N G E S + T + PS P
Sbjct: 559 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAP 605
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 71.3 bits (167), Expect = 2e-11
Identities = 64/279 (22%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 494 VTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMTQSAD 547
V W+ N ++++C P+ +W +G L S+ N+ T L ++ D
Sbjct: 424 VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 483
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGY 606
GNY C+ N G++ + + + P P + V+ Y+ + +Q+ + + GG PIL Y
Sbjct: 484 FGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKY 543
Query: 607 VINYKRE-----HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
++ H W + + + + L T Y + + A N G G +I A
Sbjct: 544 KAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLG---EISAA 600
Query: 662 YTKGTVPVK-----PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
T PV+ PK + + ++ V L DGG I ++++ YR +S +W+
Sbjct: 601 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSS-EWKPE 659
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
++ V + L A Y++ + A N G + A +
Sbjct: 660 IRLPSGSDHVM-LKSLDWNAEYEVYVVAENQQGKSKAAH 697
Score = 52.0 bits (119), Expect = 1e-05
Identities = 77/358 (21%), Positives = 139/358 (38%), Gaps = 38/358 (10%)
Query: 421 MSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
MS +DG +EE K + S + + ++ A + GE +AT + V
Sbjct: 245 MSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLR------- 529
+IT +E ++L+C G P P+ TW + + S +
Sbjct: 305 FAKP----KITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPE 360
Query: 530 KNVSSDG-----------TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP--QP 576
K + DG +LT+ Q D+G Y C+ N G+D + +EV+ P Q
Sbjct: 361 KQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG 420
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV-EAGTSEHVLPNLW 635
P+ AV + +++ + I + ++ +++ ++ ++
Sbjct: 421 PV-AVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPD 479
Query: 636 CGTRYQLY-ITAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGD 693
+ Y TA NRIG L +V A T P P Q+ ++T + +
Sbjct: 480 SENDFGNYNCTAVNRIGQESLEFILVQADT----PSSPSIDQVEPYSSTAQVQFDEPEAT 535
Query: 694 GGCGILYFVIEYREMSQPQW--RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
GG IL + E+R + + W + + E + ++ GL P Y +R+ A N G
Sbjct: 536 GGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 593
Score = 46.0 bits (104), Expect = 7e-04
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 10/124 (8%)
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRK 530
+V V P+ I + + N+ ++++L C+ G P P +WT +G + E K
Sbjct: 207 IVNVPPTIQARQNIVNATANL----GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEK 262
Query: 531 NVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
+ SD + LTI D Y C EN G + T+ +KV +P I V + A
Sbjct: 263 YIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA--TIHLKVFAKPKITYVENQTAME 320
Query: 589 LHLQ 592
L Q
Sbjct: 321 LEEQ 324
Score = 41.5 bits (93), Expect = 0.016
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P PK + + +I+++ + G SPI +Y+V+Y+ W ++ +P
Sbjct: 612 PSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEW---KPEIRLPSGSDH 668
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++L Y + ++AEN+ G+S+ + V T+ + P+ P + + ST IV
Sbjct: 669 VMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQ--PTAIPANGSPTSGLSTGAIV 725
Score = 36.3 bits (80), Expect = 0.61
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P +I ++ S T Q+ + +P A G PI+ Y +++ E W S
Sbjct: 510 PSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 568
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--TEEVPSGP 172
++ L+P T+Y +R+ A N G E S + T + PS P
Sbjct: 569 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAP 615
>AF091889-1|AAF75819.1| 1546|Homo sapiens Usher syndrome type IIa
protein protein.
Length = 1546
Score = 71.3 bits (167), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNG 1495
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
>AF055580-1|AAC23748.2| 1546|Homo sapiens Usher syndrome type IIa
protein protein.
Length = 1546
Score = 71.3 bits (167), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLKWFPPEELNG 1495
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 71.3 bits (167), Expect = 2e-11
Identities = 64/279 (22%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 494 VTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMTQSAD 547
V W+ N ++++C P+ +W +G L S+ N+ T L ++ D
Sbjct: 495 VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 554
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGY 606
GNY C+ N G++ + + + P P + V+ Y+ + +Q+ + + GG PIL Y
Sbjct: 555 FGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKY 614
Query: 607 VINYKRE-----HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
++ H W + + + + L T Y + + A N G G +I A
Sbjct: 615 KAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLG---EISAA 671
Query: 662 YTKGTVPVK-----PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
T PV+ PK + + ++ V L DGG I ++++ YR +S +W+
Sbjct: 672 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSS-EWKPE 730
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
++ V + L A Y++ + A N G + A +
Sbjct: 731 IRLPSGSDHVM-LKSLDWNAEYEVYVVAENQQGKSKAAH 768
Score = 59.3 bits (137), Expect = 8e-08
Identities = 78/348 (22%), Positives = 139/348 (39%), Gaps = 28/348 (8%)
Query: 421 MSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
MS +DG +EE K + S + + ++ A + GE +AT + V
Sbjct: 326 MSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 385
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW---TMNGVGLESTLRKNV- 532
+IT +E ++L+C G P P+ TW T N E TL ++
Sbjct: 386 FAKP----KITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 441
Query: 533 ----SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP--QPPILAVVDSYA 586
+ +LT+ Q D+G Y C+ N G+D + +EV+ P Q P+ AV
Sbjct: 442 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV-AVYTWEG 500
Query: 587 DSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV-EAGTSEHVLPNLWCGTRYQLY-I 644
+ +++ + I + ++ +++ ++ ++ + Y
Sbjct: 501 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 560
Query: 645 TAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVI 703
TA NRIG L +V A T P P Q+ ++T + + GG IL +
Sbjct: 561 TAVNRIGQESLEFILVQADT----PSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKA 616
Query: 704 EYREMSQPQW--RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
E+R + + W + + E + ++ GL P Y +R+ A N G
Sbjct: 617 EWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 664
Score = 46.0 bits (104), Expect = 7e-04
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 10/124 (8%)
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRK 530
+V V P+ I + + N+ ++++L C+ G P P +WT +G + E K
Sbjct: 288 IVNVPPTIQARQNIVNATANL----GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEK 343
Query: 531 NVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
+ SD + LTI D Y C EN G + T+ +KV +P I V + A
Sbjct: 344 YIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA--TIHLKVFAKPKITYVENQTAME 401
Query: 589 LHLQ 592
L Q
Sbjct: 402 LEEQ 405
Score = 40.3 bits (90), Expect = 0.037
Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P PK + + +I+++ + G SPI +Y+V+Y+ W ++ +P
Sbjct: 683 PSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEW---KPEIRLPSGSDH 739
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE 166
+++L Y + ++AEN+ G+S+ + V T+ +
Sbjct: 740 VMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQ 776
Score = 36.3 bits (80), Expect = 0.61
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P +I ++ S T Q+ + +P A G PI+ Y +++ E W S
Sbjct: 581 PSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 639
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--TEEVPSGP 172
++ L+P T+Y +R+ A N G E S + T + PS P
Sbjct: 640 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAP 686
>L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin
binding protein H mRNA, complete cds. ).
Length = 476
Score = 70.9 bits (166), Expect = 2e-11
Identities = 76/308 (24%), Positives = 124/308 (40%), Gaps = 20/308 (6%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSP 439
EDVPSAP + S + + VSW PP + L GY L + +G E P
Sbjct: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL--ELCREGASEWVPVSA-RP 124
Query: 440 STLSHETSRSPPRATHQFW-VSASTRLGEGEATRV---VTVLPSDSVPA-RITSFSRNI- 493
++ +T R+ VSA + G G + + + + P R+ R
Sbjct: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
Query: 494 VTPWKENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDGTLTISMTQSADSGNY 551
+ E ++L G P P TWT NG L+S + D L I Q +DSG Y
Sbjct: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
Query: 552 --TCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVI 608
T VE++ + + V ++ P P + ++D + + LQW+ Q G + +LGY++
Sbjct: 245 ELTVRVEDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
Query: 609 -NYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---K 664
++ G W + + + +L G Y + + N G + K
Sbjct: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQK 363
Query: 665 GTVPVKPK 672
+ KPK
Sbjct: 364 ADIAAKPK 371
Score = 41.5 bits (93), Expect = 0.016
Identities = 24/40 (60%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
EDVPS P L + +SS SV VSWEPP GR G LQGY
Sbjct: 68 EDVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLG-LQGY 105
Score = 40.3 bits (90), Expect = 0.037
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIV 123
S VP P + + D S ++ +SW P G + Y+++ +E W +
Sbjct: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR--- 123
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVP 169
P VT +V+NL + LR+ A + G P+ QP+ + E P
Sbjct: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
Score = 39.9 bits (89), Expect = 0.049
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 13/134 (9%)
Query: 53 DSKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAP 111
++K +D+ L + P P +IR++D + WT P GN+ ++ Y+VQ +
Sbjct: 254 EAKAVIDI----LVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
T + P T+ ++ +L SY R+ +EN G S T T+E+
Sbjct: 310 TGQWFTVLERYHP---TTCTISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHI 361
Query: 172 PPQDVRVEAKSSTE 185
D+ + K E
Sbjct: 362 QKADIAAKPKGFIE 375
>BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 70.9 bits (166), Expect = 2e-11
Identities = 76/308 (24%), Positives = 124/308 (40%), Gaps = 20/308 (6%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLSP 439
EDVPSAP + S + + VSW PP + L GY L + +G E P
Sbjct: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVL--ELCREGASEWVPVSA-RP 124
Query: 440 STLSHETSRSPPRATHQFW-VSASTRLGEGEATRV---VTVLPSDSVPA-RITSFSRNI- 493
++ +T R+ VSA + G G + + + + P R+ R
Sbjct: 125 MMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTY 184
Query: 494 VTPWKENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDGTLTISMTQSADSGNY 551
+ E ++L G P P TWT NG L+S + D L I Q +DSG Y
Sbjct: 185 IRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRY 244
Query: 552 --TCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVI 608
T VE++ + + V ++ P P + ++D + + LQW+ Q G + +LGY++
Sbjct: 245 ELTVRVEDLEAKAVIDILV-IEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
Query: 609 -NYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---K 664
++ G W + + + +L G Y + + N G + K
Sbjct: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQK 363
Query: 665 GTVPVKPK 672
+ KPK
Sbjct: 364 ADIAAKPK 371
Score = 41.5 bits (93), Expect = 0.016
Identities = 24/40 (60%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
EDVPS P L + +SS SV VSWEPP GR G LQGY
Sbjct: 68 EDVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLG-LQGY 105
Score = 40.3 bits (90), Expect = 0.037
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIV 123
S VP P + + D S ++ +SW P G + Y+++ +E W +
Sbjct: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSAR--- 123
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVP 169
P VT +V+NL + LR+ A + G P+ QP+ + E P
Sbjct: 124 PMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172
Score = 39.9 bits (89), Expect = 0.049
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 13/134 (9%)
Query: 53 DSKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAP 111
++K +D+ L + P P +IR++D + WT P GN+ ++ Y+VQ +
Sbjct: 254 EAKAVIDI----LVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
T + P T+ ++ +L SY R+ +EN G S T T+E+
Sbjct: 310 TGQWFTVLERYHP---TTCTISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHI 361
Query: 172 PPQDVRVEAKSSTE 185
D+ + K E
Sbjct: 362 QKADIAAKPKGFIE 375
Score = 36.3 bits (80), Expect = 0.61
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C+ P P W N + ++ + + +S G T+ + + + DSG YTC N+
Sbjct: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
Query: 560 GRDEVTYTVEVK 571
G V +EVK
Sbjct: 461 GEASVDCRLEVK 472
>BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein.
Length = 601
Score = 70.9 bits (166), Expect = 2e-11
Identities = 64/279 (22%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 494 VTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMTQSAD 547
V W+ N ++++C P+ +W +G L S+ N+ T L ++ D
Sbjct: 167 VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 226
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGY 606
GNY C+ N G++ + + + P P + V+ Y+ + +Q+ + + GG PIL Y
Sbjct: 227 FGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKY 286
Query: 607 VINYKRE-----HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
++ H W + + + + L T Y + + A N G G +I A
Sbjct: 287 KAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLG---EISAA 343
Query: 662 YTKGTVPVK-----PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
T PV+ PK + + ++ V L DGG I ++++ YR +S +W+
Sbjct: 344 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSS-EWKPE 402
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
++ V + L A Y++ + A N G + A +
Sbjct: 403 IRLPSGSDHVM-LKSLDWNADYEVYVVAENQQGKSKAAH 440
Score = 50.8 bits (116), Expect = 3e-05
Identities = 69/314 (21%), Positives = 124/314 (39%), Gaps = 34/314 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A + GE +AT + V +IT +E ++L+C G P P+ TW +
Sbjct: 32 AENKAGEQDATIHLKVFAKP----KITYVENQTAMELEEQVTLTCEASGDPIPSITWRTS 87
Query: 521 GVGLESTLR-------KNVSSDG-----------TLTISMTQSADSGNYTCSVENIHGRD 562
+ S + K + DG +LT+ Q D+G Y C+ N G+D
Sbjct: 88 TRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQD 147
Query: 563 EVTYTVEVKVPP--QPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEEL 620
+ +EV+ P Q P+ AV + +++ + I + ++ +
Sbjct: 148 SQSMYLEVQYAPKLQGPV-AVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 206
Query: 621 QV-EAGTSEHVLPNLWCGTRYQLY-ITAFNRIG-TGLPCDIVHAYTKGTVPVKPKHSQMI 677
++ ++ ++ + Y TA NRIG L +V A T P P Q+
Sbjct: 207 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADT----PSSPSIDQVE 262
Query: 678 TLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW--RLVSNSVQATERVFSVSGLTPA 735
++T + + GG IL + E+R + + W + + E + ++ GL P
Sbjct: 263 PYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPE 322
Query: 736 AHYQLRITAHNNAG 749
Y +R+ A N G
Sbjct: 323 TTYAVRLAALNGKG 336
Score = 41.5 bits (93), Expect = 0.016
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P PK + + +I+++ + G SPI +Y+V+Y+ W ++ +P
Sbjct: 355 PSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEW---KPEIRLPSGSDH 411
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++L Y + ++AEN+ G+S+ + V T+ + P+ P + + ST IV
Sbjct: 412 VMLKSLDWNADYEVYVVAENQQGKSKAAHFVFRTSAQ--PTAIPANGSPTSGLSTGAIV 468
Score = 36.3 bits (80), Expect = 0.61
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P +I ++ S T Q+ + +P A G PI+ Y +++ E W S
Sbjct: 253 PSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 311
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--TEEVPSGP 172
++ L+P T+Y +R+ A N G E S + T + PS P
Sbjct: 312 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAP 358
>AL445650-3|CAH70620.1| 1546|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 1546
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
>AL358858-1|CAH71587.1| 1546|Homo sapiens Usher syndrome 2A (autosomal
recessive, mild) protein.
Length = 1546
Score = 70.9 bits (166), Expect = 2e-11
Identities = 94/359 (26%), Positives = 140/359 (38%), Gaps = 44/359 (12%)
Query: 78 VIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQP 137
+I S ++ ++WT + PI YI+ P V G TSA++ NL P
Sbjct: 1157 IIPIGSDSVTLTWTTLSNQSGPIEKYILSCAPLAGGQPC----VSYEGHETSATIWNLVP 1212
Query: 138 ATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPS--GPPQDVRVEAKSSTELIVTWEPPQR 195
Y + A G S P+ VTT + P PP+ ++ SSTEL V W PP
Sbjct: 1213 FAKYDFSVQACTS-GGCLHSLPITVTTAQAPPQRLSPPKMQKI---SSTELHVEWSPPAE 1268
Query: 196 DLWNGNILGYYVGFQELNS-------NSTVLIASG-PGGASYTVRTVEGA-GTARSRTTL 246
NG I+ Y + + L S S V +SG S+ E A ++ TT+
Sbjct: 1269 --LNGIIIRYELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTI 1326
Query: 247 SGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVP--SLPPGALQCNALSSQSVRVSW 304
+GL+ + Y V A N E P +PP LSS S+ +SW
Sbjct: 1327 TGLEPYTKYEFRVLAVNMAGSVSSAWVSERTG-ESAPVFMIPPSVF---PLSSYSLNISW 1382
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT--------TLSGLRRYTNY 356
E P G + GY + + Q+ LHT T+ GL+ Y Y
Sbjct: 1383 EKPADNVTRGKVVGYDINMLSEQSPQQSIPMAFSQL--LHTAKSQELSYTVEGLKPYRIY 1440
Query: 357 SVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAV---SSRNKILVSWLPPSSPNG 412
T+ + G A+ + + +APA ++ + + I + W PP NG
Sbjct: 1441 EFTITLCNSVGCVTSAS----GAGQTLAAAPAQLRPPLVKGINSTTIHLRWFPPEELNG 1495
Score = 52.4 bits (120), Expect = 9e-06
Identities = 37/150 (24%), Positives = 70/150 (46%), Gaps = 9/150 (6%)
Query: 283 PSLPPGALQCN---ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQ 339
P +P G L + + S SV ++W + ++G ++ Y ++ AP+ G + V+ +
Sbjct: 1145 PGVPEGNLTLSYIIPIGSDSVTLTWTT--LSNQSGPIEKYILSCAPLA---GGQPCVSYE 1199
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK 399
T+ L + Y +V A T+ G + + P+ T + P + K S +
Sbjct: 1200 GHETSATIWNLVPFAKYDFSVQACTSGGC-LHSLPITVTTAQAPPQRLSPPKMQKISSTE 1258
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ V W PP+ NG+++ Y LYM + +E
Sbjct: 1259 LHVEWSPPAELNGIIIRYELYMRRLRSTKE 1288
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 70.5 bits (165), Expect = 3e-11
Identities = 64/279 (22%), Positives = 118/279 (42%), Gaps = 22/279 (7%)
Query: 494 VTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMTQSAD 547
V W+ N ++++C P+ +W +G L S+ N+ T L ++ D
Sbjct: 414 VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSEND 473
Query: 548 SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSD-QGDGGSPILGY 606
GNY C+ N G++ + + P P + V+ Y+ + +Q+ + + GG PIL Y
Sbjct: 474 FGNYNCTAVNRIGQESFEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKY 533
Query: 607 VINYKRE-----HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHA 661
++ H W + + + + L T Y + + A N G G +I A
Sbjct: 534 KAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLG---EISAA 590
Query: 662 YTKGTVPVK-----PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLV 716
T PV+ PK + + ++ V L DGG I ++++ YR +S +W+
Sbjct: 591 SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSS-EWKPE 649
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHALALY 755
++ V + L A Y++ + A N G + A +
Sbjct: 650 IRLPSGSDHVM-LKSLDWNAEYEVYVVAENQQGKSKAAH 687
Score = 57.6 bits (133), Expect = 2e-07
Identities = 74/347 (21%), Positives = 135/347 (38%), Gaps = 26/347 (7%)
Query: 421 MSVIEDG----REEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTV 476
MS +DG +EE K + S + + ++ A + GE +AT + V
Sbjct: 245 MSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Query: 477 LPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTW---TMNGVGLESTLRKNV- 532
+IT +E ++L+C G P P+ TW T N E TL ++
Sbjct: 305 FAKP----KITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 360
Query: 533 ----SSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP--QPPILAVVDSYA 586
+ +LT+ Q D+G Y C+ N G+D + +EV+ P Q P+ AV
Sbjct: 361 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPV-AVYTWEG 419
Query: 587 DSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQV-EAGTSEHVLPNLWCGTRYQLY-I 644
+ +++ + I + ++ +++ ++ ++ + Y
Sbjct: 420 NQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNC 479
Query: 645 TAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIE 704
TA NRIG + P P Q+ ++T + + GG IL + E
Sbjct: 480 TAVNRIGQE---SFEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAE 536
Query: 705 YREMSQPQW--RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
+R + + W + + E + ++ GL P Y +R+ A N G
Sbjct: 537 WRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKG 583
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRK 530
+V V P+ I + + N+ ++++L C+ P P +WT +G + E K
Sbjct: 207 IVNVPPTIRARQNIVNATANL----GQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEK 262
Query: 531 NVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADS 588
+ SD + LTI D Y C EN G + T+ +KV +P I V + A
Sbjct: 263 YIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA--TIHLKVFAKPKITYVENQTAME 320
Query: 589 LHLQ 592
L Q
Sbjct: 321 LEEQ 324
Score = 41.5 bits (93), Expect = 0.016
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
P PK + + +I+++ + G SPI +Y+V+Y+ W ++ +P
Sbjct: 602 PSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEW---KPEIRLPSGSDH 658
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIV 188
+++L Y + ++AEN+ G+S+ + V T+ + P+ P + + ST IV
Sbjct: 659 VMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQ--PTAIPANGSPTSGLSTGAIV 715
Score = 36.3 bits (80), Expect = 0.61
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P P +I ++ S T Q+ + +P A G PI+ Y +++ E W S
Sbjct: 500 PSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 558
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTT--TEEVPSGP 172
++ L+P T+Y +R+ A N G E S + T + PS P
Sbjct: 559 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAP 605
>BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,
165kDa protein.
Length = 1465
Score = 70.5 bits (165), Expect = 3e-11
Identities = 119/516 (23%), Positives = 199/516 (38%), Gaps = 60/516 (11%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTK----QI 340
P LQC+ + V V+W+PP + ++ GY V V +W DA K +
Sbjct: 386 PMDLQCHDANRDYVIVTWKPPNTTTESPVM-GYFVDRCEVGTNNWVQCNDAPVKICKYPV 444
Query: 341 SGLHTTLS-----------GLRRYTNYSVTVCAFTAAG---------DGVRAAPVY---C 377
+GL S G+ R + S V A +G + +Y
Sbjct: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
+ VP P + A+ SRN +++SW PP+ + Y + SV+ G + + +
Sbjct: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTA 564
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--------VTVLPSDSVPARITSF 489
S + ++ F V ++ R G E + + VTV+PS P R+ +
Sbjct: 565 VRSP-RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGRVLA- 620
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSAD- 547
SRN T ++ + + G L E K + + + +T
Sbjct: 621 SRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680
Query: 548 -----SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGS 601
+ N EN D + + VP P + +++ S+ L W + GGS
Sbjct: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740
Query: 602 PILGYVINYKRE--HGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCD- 657
PILGY ++ KRE H +W E+ + + L G+ Y+ I A N G G P D
Sbjct: 741 PILGYYLD-KREVHHKNWHEVNSSPSKPTILTVDGLMEGSLYEFKIAAVNLAGIGEPSDP 799
Query: 658 IVHAYTKGTVPVKPKHSQMITL----NTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
H + +P + +T +T+ V +W G + + +++RE +W
Sbjct: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859
Query: 714 RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V+ + A+ R VS L Y R+ A N G
Sbjct: 860 ITVNQTTTAS-RYLKVSDLQQGKTYVFRVRAVNANG 894
Score = 59.7 bits (138), Expect = 6e-08
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP P I +++ ++ + W P ++G SPI+ Y + +E ++W P
Sbjct: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS---PSK 766
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE--EVPS-GPPQDVRVEAKSS 183
T +V L + Y +I A N G EPS P + E +P GP D+
Sbjct: 767 PTILTVDGLMEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826
Query: 184 TELIVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLI 220
T L++ W+ P +++G+ + GY+V F+E ++ + +
Sbjct: 827 TSLVMLWKAP---VYSGSSPVSGYFVDFREEDAGEWITV 862
Score = 58.8 bits (136), Expect = 1e-07
Identities = 113/553 (20%), Positives = 205/553 (37%), Gaps = 41/553 (7%)
Query: 141 YHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPP---QDVRVEAKSSTELIVTWEPPQRDL 197
Y LRI++ R G S+ S + V + + +G P D++ + +IVTW+PP
Sbjct: 353 YTLRIVS--RGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTT 410
Query: 198 WNGNILGYYVGFQELNSNSTVLIASGP------------GGASYT--VRTVEGAGTAR-S 242
++GY+V E+ +N+ V P G SY VR V AG +R S
Sbjct: 411 -ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPS 469
Query: 243 RTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRV 302
R + + +QA + + PP + + +S V +
Sbjct: 470 RVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVL 529
Query: 303 SWEPPPMRGRNGILQGYRVTYAPVTDWY--GNEDAVTKQISGLHTTLSGLRRYTNYSVTV 360
SWEPP RG++ ++ + W + AV + + G + Y ++
Sbjct: 530 SWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEG-KSYVFRVLSA 588
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLY 420
+ +P+ VPSAP + A+ +++ ++V W P L+GY +
Sbjct: 589 NRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEED-LLGYYVD 647
Query: 421 MSVIEDGR-EEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
V E HK + + H + V+A + + V+ V +
Sbjct: 648 CCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAA 707
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-- 537
+VP+ + + K +P + ++ + V+S +
Sbjct: 708 LTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKP 767
Query: 538 --LTISMTQSADSGNYTCSVENIHGRDEVT-----YTVEVKVPPQP-PI--LAVVDSYAD 587
LT+ + + N+ G E + + E P+P P L +
Sbjct: 768 TILTVDGLMEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDT 827
Query: 588 SLHLQW-SDQGDGGSPILGYVINYKREH-GDWEELQVEAGTSEHV-LPNLWCGTRYQLYI 644
SL + W + G SP+ GY ++++ E G+W + S ++ + +L G Y +
Sbjct: 828 SLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTASRYLKVSDLQQGKTYVFRV 887
Query: 645 TAFNRIGTGLPCD 657
A N G G P D
Sbjct: 888 RAVNANGVGKPSD 900
Score = 40.7 bits (91), Expect = 0.028
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT----QSADSGNYTCS 554
+ ++L+C G P P W N ++ + +V + +SMT S DSG Y+ +
Sbjct: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSIN 1419
Query: 555 VENIHGRDEVTYTVEV-----KVPPQPP 577
++N +G +++ TV V K+P P
Sbjct: 1420 IKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447
>X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein.
Length = 1465
Score = 69.7 bits (163), Expect = 5e-11
Identities = 119/516 (23%), Positives = 198/516 (38%), Gaps = 60/516 (11%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVTK----QI 340
P LQC+ + V V+W+PP + ++ GY V V +W DA K +
Sbjct: 386 PMDLQCHDANRDYVIVTWKPPNTTTESPVM-GYFVDRCEVGTNNWVQCNDAPVKICKYPV 444
Query: 341 SGLHTTLS-----------GLRRYTNYSVTVCAFTAAG---------DGVRAAPVY---C 377
+GL S G+ R + S V A +G + +Y
Sbjct: 445 TGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDL 504
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
+ VP P + A+ SRN +++SW PP+ + Y + SV+ G + + +
Sbjct: 505 EGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGTWQRVNAQTA 564
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV--------VTVLPSDSVPARITSF 489
S + ++ F V ++ R G E + + VTV+PS P R+ +
Sbjct: 565 VRSP-RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPS--APGRVLA- 620
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSAD- 547
SRN T ++ + + G L E K + + + +T
Sbjct: 621 SRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680
Query: 548 -----SGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGS 601
+ N EN D + + VP P + +++ S+ L W + GGS
Sbjct: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740
Query: 602 PILGYVINYKRE--HGDWEELQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCD- 657
PILGY ++ KRE H +W E+ + + L G+ Y+ I A N G G P D
Sbjct: 741 PILGYYLD-KREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDP 799
Query: 658 IVHAYTKGTVPVKPKHSQMITL----NTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQW 713
H + +P + +T +T+ V +W G + + +++RE +W
Sbjct: 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEW 859
Query: 714 RLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
V + A+ R VS L Y R+ A N G
Sbjct: 860 ITVDQTTTAS-RYLKVSDLQQGKTYVFRVRAVNANG 894
Score = 59.3 bits (137), Expect = 8e-08
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP-ESWPSTPQKVIVPGS 126
VP P I +++ ++ + W P ++G SPI+ Y + +E ++W P
Sbjct: 710 VPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSS---PSK 766
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE--EVPS-GPPQDVRVEAKSS 183
T +V L + Y +I A N G EPS P + E +P GP D+
Sbjct: 767 PTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRD 826
Query: 184 TELIVTWEPPQRDLWNGN--ILGYYVGFQELNSNSTVLI 220
T L++ W+ P +++G+ + GY+V F+E ++ + +
Sbjct: 827 TSLVMLWKAP---VYSGSSPVSGYFVDFREEDAGEWITV 862
Score = 56.8 bits (131), Expect = 4e-07
Identities = 104/520 (20%), Positives = 189/520 (36%), Gaps = 36/520 (6%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP------ 224
G P D++ + +IVTW+PP ++GY+V E+ +N+ V P
Sbjct: 384 GAPMDLQCHDANRDYVIVTWKPPNTTT-ESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442
Query: 225 ------GGASYT--VRTVEGAGTAR-SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXX 275
G SY VR V AG +R SR + + +QA +
Sbjct: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502
Query: 276 XXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWY--GNE 333
+ PP + + +S V +SWEPP RG++ ++ + W +
Sbjct: 503 DLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGTWQRVNAQ 562
Query: 334 DAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAA 393
AV + + G + Y ++ + +P+ VPSAP + A+
Sbjct: 563 TAVRSPRYAVFDLMEG-KSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLAS 621
Query: 394 VSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGR-EEGTHKRMLSPSTLSHETSRSPPR 452
+++ ++V W P L+GY + V E HK + + H +
Sbjct: 622 RNTKTSVVVQWDRPKHEED-LLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQY 680
Query: 453 ATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPA 512
V+A + + V+ V + +VP+ + + K +
Sbjct: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740
Query: 513 PATTWTMNGVGLESTLRKNVSSDGT----LTISMTQSADSGNYTCSVENIHGRDEVT--- 565
P + ++ + V+S + LT+ + + N+ G E +
Sbjct: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800
Query: 566 --YTVEVKVPPQP-PI--LAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREH-GDWE 618
+ E P+P P L + SL + W + G SP+ GY ++++ E G+W
Sbjct: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860
Query: 619 ELQVEAGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCD 657
+ S ++ + +L G Y + A N G G P D
Sbjct: 861 TVDQTTTASRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD 900
Score = 40.7 bits (91), Expect = 0.028
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMT----QSADSGNYTCS 554
+ ++L+C G P P W N ++ + +V + +SMT S DSG Y+ +
Sbjct: 1360 KTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSIN 1419
Query: 555 VENIHGRDEVTYTVEV-----KVPPQPP 577
++N +G +++ TV V K+P P
Sbjct: 1420 IKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447
>X53587-1|CAA37656.1| 1822|Homo sapiens integrin beta 4 protein
protein.
Length = 1822
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1641 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1699
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1700 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1741
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---- 342
PG L ALS S+++SWE P R NG + GY VT G A ++ G
Sbjct: 1644 PGPLVFTALSPDSLQLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPE 1698
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDG 369
T+ GL Y V A T G G
Sbjct: 1699 SRLTVPGLSENVPYKFKVQARTTEGFG 1725
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1656 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1715
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1716 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1744
>X52186-1|CAA36433.1| 1805|Homo sapiens integrin beta 4 subunit
protein.
Length = 1805
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1624 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1682
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1683 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1724
Score = 36.7 bits (81), Expect = 0.46
Identities = 65/253 (25%), Positives = 93/253 (36%), Gaps = 21/253 (8%)
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
GS + A ++ P+ II R + PS T VP P + V A T
Sbjct: 1469 GSRSRAQMKGFPPSRGPRDSIILAGR--PAAPSWGPDSRLTAGVPDTPTRLV-FSALGPT 1525
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV-LIASGPGGASYTVRTV--EGAGTAR 241
L V+W+ P+ + + GY V +Q LN L P S V + + R
Sbjct: 1526 SLRVSWQEPRCER---PLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1582
Query: 242 SRT-TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
R + G + + +++ + PS P G L ALS S+
Sbjct: 1583 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLS-TPSAP-GPLVFTALSPDSL 1640
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG----LHTTLSGLRRYTNY 356
++SWE P R NG + GY VT G A ++ G T+ GL Y
Sbjct: 1641 QLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPESRLTVPGLSENVPY 1695
Query: 357 SVTVCAFTAAGDG 369
V A T G G
Sbjct: 1696 KFKVQARTTEGFG 1708
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1639 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1698
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1699 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1727
>X51841-1|CAA36134.1| 1752|Homo sapiens protein ( Human mRNA for
integrin beta(4)subunit. ).
Length = 1752
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1629
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1630 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---- 342
PG L ALS S+++SWE P R NG + GY VT G A ++ G
Sbjct: 1574 PGPLVFTALSPDSLQLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPE 1628
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDG 369
T+ GL Y V A T G G
Sbjct: 1629 SRLTVPGLSENVPYKFKVQARTTEGFG 1655
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1586 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1645
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1646 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1674
>U66541-3|AAC51632.1| 1752|Homo sapiens beta4-integrin protein.
Length = 1752
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1629
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1630 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---- 342
PG L ALS S+++SWE P R NG + GY VT G A ++ G
Sbjct: 1574 PGPLVFTALSPDSLQLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPE 1628
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDG 369
T+ GL Y V A T G G
Sbjct: 1629 SRLTVPGLSENVPYKFKVQARTTEGFG 1655
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1586 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1645
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1646 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1674
>U66541-2|AAC51634.1| 1805|Homo sapiens beta4-integrin protein.
Length = 1805
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1624 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1682
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1683 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1724
Score = 36.7 bits (81), Expect = 0.46
Identities = 65/253 (25%), Positives = 93/253 (36%), Gaps = 21/253 (8%)
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
GS + A ++ P+ II R + PS T VP P + V A T
Sbjct: 1469 GSRSRAQMKGFPPSRGPRDSIILAGR--PAAPSWGPDSRLTAGVPDTPTRLV-FSALGPT 1525
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV-LIASGPGGASYTVRTV--EGAGTAR 241
L V+W+ P+ + + GY V +Q LN L P S V + + R
Sbjct: 1526 SLRVSWQEPRCER---PLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1582
Query: 242 SRT-TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
R + G + + +++ + PS P G L ALS S+
Sbjct: 1583 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLS-TPSAP-GPLVFTALSPDSL 1640
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG----LHTTLSGLRRYTNY 356
++SWE P R NG + GY VT G A ++ G T+ GL Y
Sbjct: 1641 QLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPESRLTVPGLSENVPY 1695
Query: 357 SVTVCAFTAAGDG 369
V A T G G
Sbjct: 1696 KFKVQARTTEGFG 1708
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1639 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1698
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1699 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1727
>U66541-1|AAC51633.1| 1822|Homo sapiens beta4-integrin protein.
Length = 1822
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 38.3 bits (85), Expect = 0.15
Identities = 74/338 (21%), Positives = 124/338 (36%), Gaps = 28/338 (8%)
Query: 167 EVPSGPPQDVRVEAKS-STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG 225
E P GPP D K S T PP L NG + + G T A+ G
Sbjct: 1411 EAPHGPPDDGGAGGKGGSLPRSATPGPPGEHLVNGRMDFAFPGSTNSLHRMTTTSAAAYG 1470
Query: 226 G--ASYTVRTVEGAGTARSRTTLSGLQ-KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV 282
+ + V + +R S + +H+ + + Y++ + D
Sbjct: 1471 THLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVPDT 1530
Query: 283 PSLPPGALQCNALSSQSVRVSWEPP----PMRGRN---GILQGYRVTYAPVTDWYGNEDA 335
P+ L +AL S+RVSW+ P P++G + +L G + + +
Sbjct: 1531 PT----RLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIPN-PAQTSV 1585
Query: 336 VTKQISGLHTTLSGLRRYTNYS--------VTVCAFTAAGDGVRAAPVYCHTEEDVPSAP 387
V + + H+ + +R + +T+ + + P T PSAP
Sbjct: 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLS-TPSAP 1644
Query: 388 ADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETS 447
+ S + + +SW P PNG +VGY + + + G T R+ S S T
Sbjct: 1645 GPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPESRLTV 1703
Query: 448 RS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
++F V A T G G E ++T+ D P
Sbjct: 1704 PGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1741
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1656 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1715
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1716 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1744
>U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 69.7 bits (163), Expect = 5e-11
Identities = 79/310 (25%), Positives = 127/310 (40%), Gaps = 24/310 (7%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTLYMSVIEDGREEGTHKRMLS- 438
EDVPSAP + S + + VSW PP + L GY V+E RE G+ +S
Sbjct: 68 EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGY-----VLELCREGGSEWVPVSA 122
Query: 439 -PSTLSHETSRSPPRATHQFW-VSASTRLGEGEATRV---VTVLPSDSVPA-RITSFSRN 492
P ++ +T R+ VSA G G + + + + P R+ R
Sbjct: 123 RPMMVTQQTVRNLALGDKFLLRVSAVRPAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQ 182
Query: 493 I-VTPWKENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDGTLTISMTQSADSG 549
+ E ++L G P P TWT NG L+S + D L I Q +DSG
Sbjct: 183 TYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSG 242
Query: 550 NY--TCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS-DQGDGGSPILGY 606
Y T VE++ + + V ++ P P + ++D + + LQW+ Q G + +LGY
Sbjct: 243 RYELTVRVEDLEAKAVIDILV-IEKPGPPCCIRLLDVWGCNAALQWTPPQDTGNTELLGY 301
Query: 607 VI-NYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT-- 663
++ ++ G W + + + +L G Y + + N G +
Sbjct: 302 MVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHI 361
Query: 664 -KGTVPVKPK 672
K + KPK
Sbjct: 362 QKADIAAKPK 371
Score = 41.5 bits (93), Expect = 0.016
Identities = 24/40 (60%), Positives = 26/40 (65%), Gaps = 2/40 (5%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
EDVPS P L + +SS SV VSWEPP GR G LQGY
Sbjct: 68 EDVPSAPL-LLTLDDVSSSSVTVSWEPPERLGRLG-LQGY 105
Score = 39.1 bits (87), Expect = 0.086
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 8/109 (7%)
Query: 66 SHQVPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQY-KEAPESWPSTPQKVIV 123
S VP P + + D S ++ +SW P G + Y+++ +E W +
Sbjct: 67 SEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGGSEWVPVSAR--- 123
Query: 124 PGSVTSASVQNLQPATSYHLRIIAENRLGQSEPS---QPVQVTTTEEVP 169
P VT +V+NL + LR+ A G P+ QP+ + E P
Sbjct: 124 PMMVTQQTVRNLALGDKFLLRVSAVRPAGAGPPAMLDQPIHIRENIEAP 172
Score = 37.1 bits (82), Expect = 0.35
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 13/134 (9%)
Query: 53 DSKVTVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAP 111
++K +D+ L + P P IR++D + WT P GN+ ++ Y+VQ +
Sbjct: 254 EAKAVIDI----LVIEKPGPPCCIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKK 309
Query: 112 ESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSG 171
T + P T+ ++ +L SY R+ +EN G S T T+E+
Sbjct: 310 TGQWFTVLERYHP---TTCTISDLIIGNSYSFRVFSENLCGLS-----TSATVTKELAHI 361
Query: 172 PPQDVRVEAKSSTE 185
D+ + K E
Sbjct: 362 QKADIAAKPKGFIE 375
Score = 36.3 bits (80), Expect = 0.61
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLESTLR-KNVSSDGTLTISMTQSA--DSGNYTCSVENIH 559
L C+ P P W N + ++ + + +S G T+ + + + DSG YTC N+
Sbjct: 401 LFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVL 460
Query: 560 GRDEVTYTVEVK 571
G V +EVK
Sbjct: 461 GEASVDCRLEVK 472
>BC126411-1|AAI26412.1| 1752|Homo sapiens integrin, beta 4 protein.
Length = 1752
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1629
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1630 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---- 342
PG L ALS S+++SWE P R NG + GY VT G A ++ G
Sbjct: 1574 PGPLVFTALSPDSLQLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPE 1628
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDG 369
T+ GL Y V A T G G
Sbjct: 1629 SRLTVPGLSENVPYKFKVQARTTEGFG 1655
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1586 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1645
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1646 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1674
>BC118916-1|AAI18917.1| 1752|Homo sapiens ITGB4 protein protein.
Length = 1752
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1137 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1189
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1190 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1249
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1250 ITAYEVCYGLVNDDNRPIGPMKKVL 1274
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1241
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1242 EP--AETNGEITAYEVCYGLVND 1262
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1629
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1630 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1671
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1129 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1182
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1183 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1232
Score = 34.3 bits (75), Expect = 2.4
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG---- 342
PG L ALS S+++SWE P R NG + GY VT G A ++ G
Sbjct: 1574 PGPLVFTALSPDSLQLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPE 1628
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDG 369
T+ GL Y V A T G G
Sbjct: 1629 SRLTVPGLSENVPYKFKVQARTTEGFG 1655
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1586 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1645
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1646 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1674
>AJ251004-1|CAB61345.1| 1873|Homo sapiens integrin beta 4 protein.
Length = 1873
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1136 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1188
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1189 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1248
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1249 ITAYEVCYGLVNDDNRPIGPMKKVL 1273
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1182 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1240
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1241 EP--AETNGEITAYEVCYGLVND 1261
Score = 37.5 bits (83), Expect = 0.26
Identities = 83/344 (24%), Positives = 126/344 (36%), Gaps = 29/344 (8%)
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSST 184
GS + A ++ P+ II R + PS T VP P + V A T
Sbjct: 1538 GSRSRAQMKGFPPSRGPRDSIILAGR--PAAPSWGPDSRLTAGVPDTPTRLV-FSALGPT 1594
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTV-LIASGPGGASYTVRTV--EGAGTAR 241
L V+W+ P+ + + GY V +Q LN L P S V + + R
Sbjct: 1595 SLRVSWQEPRCER---PLQGYSVEYQLLNGGELHRLNIPNPAQTSVVVEDLLPNHSYVFR 1651
Query: 242 SRT-TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
R + G + + +++ + PS P G L ALS S+
Sbjct: 1652 VRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLS-TPSAP-GPLVFTALSPDSL 1709
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG----LHTTLSGLRRYTNY 356
++SWE P R NG + GY VT G A ++ G T+ GL Y
Sbjct: 1710 QLSWERP--RRPNGDIVGYLVTCEMA---QGGGPATAFRVDGDSPESRLTVPGLSENVPY 1764
Query: 357 SVTVCAFTAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSR----NKILVSWLPPSSPN 411
V A T G G R + +++ P +A + +S S+
Sbjct: 1765 KFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSRAGLFQHPLQSEYSSISTTHTSATE 1824
Query: 412 GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATH 455
LVG TL +E G G+ R ++ +S + S +TH
Sbjct: 1825 PFLVGPTLGAQHLEAG---GSLTRHVTQEFVSRTLTTSGTLSTH 1865
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Query: 384 PSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLS 443
PSAP + S + + +SW P PNG +VGY + + + G T R+ S S
Sbjct: 1693 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGG-GPATAFRVDGDSPES 1751
Query: 444 HETSRS-PPRATHQFWVSASTRLGEG-EATRVVTVLPSDSVP 483
T ++F V A T G G E ++T+ D P
Sbjct: 1752 RLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGP 1793
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1128 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1181
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1182 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1231
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLR 144
++Q+SW +P N I+ Y+V + A P+T +V + +V L Y +
Sbjct: 1708 SLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFK 1767
Query: 145 IIAENRLGQSEPSQPVQVTTTEEVPSGP-PQ 174
+ A G + + T E GP PQ
Sbjct: 1768 VQARTTEGFGPERE--GIITIESQDGGPFPQ 1796
>AB208913-1|BAD92150.1| 1515|Homo sapiens integrin beta 4 isoform 3
precursor variant protein.
Length = 1515
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 294 ALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRY 353
A S+ + +W PP +G GYRV Y D + ++ + L+ L Y
Sbjct: 1169 AAGSRKIHFNWLPP-----SGKPMGYRVKYWIQGDSESEAHLLDSKVPSVE--LTNLYPY 1221
Query: 354 TNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV 413
+Y + VCA+ A G+G ++ V C T ++VPS P + V S +SW P+ NG
Sbjct: 1222 CDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGE 1281
Query: 414 LVGYTL-YMSVIEDGREEGTHKRML 437
+ Y + Y V +D R G K++L
Sbjct: 1282 ITAYEVCYGLVNDDNRPIGPMKKVL 1306
Score = 37.9 bits (84), Expect = 0.20
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 246 LSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWE 305
L+ L + Y + V AY ++ ++VPS PG L N +SS ++SW
Sbjct: 1215 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPS-EPGRLAFNVVSSTVTQLSWA 1273
Query: 306 PPPMRGRNGILQGYRVTYAPVTD 328
P NG + Y V Y V D
Sbjct: 1274 EP--AETNGEITAYEVCYGLVND 1294
Score = 35.9 bits (79), Expect = 0.80
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 386 APADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHE 445
AP + A + KI +WLPPS G +GY + + D E +L S E
Sbjct: 1161 APQNPNAKAAGSRKIHFNWLPPS---GKPMGYRVKYWIQGDSESEA---HLLDSKVPSVE 1214
Query: 446 TSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVT 495
+ P ++ V A GEG + +V+ VP+ + N+V+
Sbjct: 1215 LTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVS 1264
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 68.9 bits (161), Expect = 9e-11
Identities = 81/317 (25%), Positives = 127/317 (40%), Gaps = 23/317 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSV 127
P P V + +I ++W + + +Y+++ A +W + V +
Sbjct: 556 PGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGV----QL 611
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTE 185
+ +V LQP T Y + A G SEPS PV V T + PS P +D + E
Sbjct: 612 ETHTVSGLQPNTIYLFLVRAVGAWGLSEPS-PVSEPVRTQDSSPSRPVEDPWRGQQGLAE 670
Query: 186 LIVTWEPP----QRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+ V + P R L + V Q + +GP G S+T+ ++ ++
Sbjct: 671 VAVRLQEPIVLGPRTLQVSWTVDGPV--QLVQGFRVSWRVAGPEGGSWTMLDLQSP--SQ 726
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQS 299
T L GL + VQA E+ PS PP A+ + S
Sbjct: 727 QSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSS 786
Query: 300 VRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
+ VSWEPP +NG++ Y++ + ++ N A S + L GL Y
Sbjct: 787 ITVSWEPPLPSQQNGVITEYQIWCLGNESRFHLNRSAAGWARSAM---LRGLVPGLLYRT 843
Query: 359 TVCAFTAAGDGVRAAPV 375
V A T+AG GV +APV
Sbjct: 844 LVAAATSAGVGVPSAPV 860
Score = 49.2 bits (112), Expect = 8e-05
Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
++ C G P P W G T R + SD +L I + D G YTC EN G
Sbjct: 275 VTFLCEVKGDPPPRLRWRKED-GELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVG 333
Query: 561 RDEVTYTVEVKVPPQ 575
R E + ++ V VPPQ
Sbjct: 334 RAEASGSLSVHVPPQ 348
Score = 46.0 bits (104), Expect = 7e-04
Identities = 50/213 (23%), Positives = 80/213 (37%), Gaps = 23/213 (10%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTL 538
D +P I N ++ L C G P P+ W +G L+ L+ ++GTL
Sbjct: 447 DGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTL 506
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVK------VPPQPPI-----------LAV 581
I+ Q D G Y+C ++ G E T++ +K V P PP V
Sbjct: 507 YIANVQEMDMGFYSCVAKSSTG--EATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVV 564
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVIN-YKREHGD-WEELQVEAGTSEHVLPNLWCGTR 639
+ +S+ L W G+ + YVI + G+ W + H + L T
Sbjct: 565 TEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTI 624
Query: 640 YQLYITAFNRIGTGLPCDIVH-AYTKGTVPVKP 671
Y + A G P + T+ + P +P
Sbjct: 625 YLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSRP 657
Score = 42.3 bits (95), Expect = 0.009
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G EA+ ++V VP ++ + ++ + E+++ C G P PA W
Sbjct: 328 AENSVGRAEASGSLSV----HVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKE 383
Query: 521 GV--------GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
G L+ T R +VS G L I+ Q D+G Y C ++ G +E+K
Sbjct: 384 GSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIK 442
Score = 40.3 bits (90), Expect = 0.037
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 492 NIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
N+V E L C G P P+ +W +G L+ + G L +S T +D+G
Sbjct: 174 NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGM 233
Query: 551 YTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
Y C N+ G E + EV V +P L
Sbjct: 234 YVCVASNMAGERE-SAAAEVMVLERPSFL 261
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 68.9 bits (161), Expect = 9e-11
Identities = 81/317 (25%), Positives = 127/317 (40%), Gaps = 23/317 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQY--KEAPESWPSTPQKVIVPGSV 127
P P V + +I ++W + + +Y+++ A +W + V +
Sbjct: 556 PGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGV----QL 611
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ--VTTTEEVPSGPPQDVRVEAKSSTE 185
+ +V LQP T Y + A G SEPS PV V T + PS P +D + E
Sbjct: 612 ETHTVSGLQPNTIYLFLVRAVGAWGLSEPS-PVSEPVRTQDSSPSRPVEDPWRGQQGLAE 670
Query: 186 LIVTWEPP----QRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+ V + P R L + V Q + +GP G S+T+ ++ ++
Sbjct: 671 VAVRLQEPIVLGPRTLQVSWTVDGPV--QLVQGFRVSWRVAGPEGGSWTMLDLQSP--SQ 726
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPG--ALQCNALSSQS 299
T L GL + VQA E+ PS PP A+ + S
Sbjct: 727 QSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSS 786
Query: 300 VRVSWEPPPMRGRNGILQGYRV-TYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSV 358
+ VSWEPP +NG++ Y++ + ++ N A S + L GL Y
Sbjct: 787 ITVSWEPPLPSQQNGVITEYQIWCLGNESRFHLNRSAAGWARSAM---LRGLVPGLLYRT 843
Query: 359 TVCAFTAAGDGVRAAPV 375
V A T+AG GV +APV
Sbjct: 844 LVAAATSAGVGVPSAPV 860
Score = 49.2 bits (112), Expect = 8e-05
Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
++ C G P P W G T R + SD +L I + D G YTC EN G
Sbjct: 275 VTFLCEVKGDPPPRLRWRKED-GELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVG 333
Query: 561 RDEVTYTVEVKVPPQ 575
R E + ++ V VPPQ
Sbjct: 334 RAEASGSLSVHVPPQ 348
Score = 46.0 bits (104), Expect = 7e-04
Identities = 50/213 (23%), Positives = 80/213 (37%), Gaps = 23/213 (10%)
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTL 538
D +P I N ++ L C G P P+ W +G L+ L+ ++GTL
Sbjct: 447 DGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTL 506
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVK------VPPQPPI-----------LAV 581
I+ Q D G Y+C ++ G E T++ +K V P PP V
Sbjct: 507 YIANVQEMDMGFYSCVAKSSTG--EATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVV 564
Query: 582 VDSYADSLHLQWSDQGDGGSPILGYVIN-YKREHGD-WEELQVEAGTSEHVLPNLWCGTR 639
+ +S+ L W G+ + YVI + G+ W + H + L T
Sbjct: 565 TEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTI 624
Query: 640 YQLYITAFNRIGTGLPCDIVH-AYTKGTVPVKP 671
Y + A G P + T+ + P +P
Sbjct: 625 YLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSRP 657
Score = 41.9 bits (94), Expect = 0.012
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A +G EA+ ++V VP ++ + ++ + E+++ C G P PA W
Sbjct: 328 AENSVGRAEASGSLSV----HVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKE 383
Query: 521 GV--------GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVK 571
G L+ T R +VS G L I+ Q D+G Y C ++ G +E+K
Sbjct: 384 GSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIK 442
Score = 40.3 bits (90), Expect = 0.037
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 492 NIVTPWKENISLSCNKV-GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGN 550
N+V E L C G P P+ +W +G L+ + G L +S T +D+G
Sbjct: 174 NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGM 233
Query: 551 YTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
Y C N+ G E + EV V +P L
Sbjct: 234 YVCVASNMAGERE-SAAAEVMVLERPSFL 261
>X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein.
Length = 1138
Score = 68.5 bits (160), Expect = 1e-10
Identities = 58/206 (28%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 509 GVPAPATTWTMNGVGL-ESTLRKNVSS---DGTLTISMTQSADSGNYTCSVENIHGRDEV 564
G P P W+ + E + R S TL I + + DSG Y +++N G
Sbjct: 549 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 608
Query: 565 TYTVEVKVPPQPPILAVVDSYADS-LHLQWSDQG-DGGSPILGYVINYKREHGD-WEELQ 621
+ V+V P PP+ V D + W DGGSPILGY I K++ W L
Sbjct: 609 SIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 668
Query: 622 VEAGTSEHVLPNLWC-GTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLN 680
+ P G Y++ I A N IG P + V P + ++
Sbjct: 669 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVT 728
Query: 681 TTTVTV-WLDSWGDGGCGILYFVIEY 705
TTVT+ W G G+ +V+EY
Sbjct: 729 DTTVTMRWRPPDHIGAAGLDGYVLEY 754
Score = 48.8 bits (111), Expect = 1e-04
Identities = 44/184 (23%), Positives = 83/184 (45%), Gaps = 13/184 (7%)
Query: 88 ISWTQP-YAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
++W P Y G SPI+ Y ++ K+ S W + T+ + + +Y +RI
Sbjct: 636 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC---KETTFEPKKMIEGVAYEVRI 692
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
A N +G S+PS P + V S PP + V++ + T + + W PP + + GY
Sbjct: 693 FAVNAIGISKPSMPSRPFVPLAVTS-PPTLLTVDSVTDTTVTMRWRPPDH-IGAAGLDGY 750
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGT-----ARSRTTLSGLQKHAAYAVVVQ 260
+ + +++ + G A+Y + + +++ T++GL A V V+
Sbjct: 751 VLEYC-FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 809
Query: 261 AYNS 264
A N+
Sbjct: 810 AVNA 813
Score = 41.1 bits (92), Expect = 0.021
Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 6/148 (4%)
Query: 509 GVPAPATTWTMNGVGLESTLR--KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTY 566
G P P TW +G ++ +N +D + I + + SG Y V+ + +
Sbjct: 863 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 922
Query: 567 TVEVKVPPQPP-ILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKREHGDWEELQVEA 624
+ + P PP I+ + D + ++ L W+ DG + I GY I K + E L+V
Sbjct: 923 DIRIIDRPGPPQIVKIEDVWGRNVALTWTPPKDDGNAAITGYTIQ-KADKKSMEWLRVIE 981
Query: 625 GTSEHV-LPNLWCGTRYQLYITAFNRIG 651
E V L G Y + + N G
Sbjct: 982 HIIEPVPHTELVIGNEYYFRVFSENMCG 1009
Score = 40.3 bits (90), Expect = 0.037
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD---GTLTISMTQSADSGNYTCSVENI 558
+L+C+ G P P TW N V + R + S+ TL I D G Y C N
Sbjct: 1062 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLGVCTLEIGKPSPYDGGTYCCKAVND 1121
Query: 559 HGRDEVTYTVEVKVPPQ 575
G E+ +EVKV Q
Sbjct: 1122 LGTVEIECKLEVKVIAQ 1138
Score = 39.1 bits (87), Expect = 0.086
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPY-AGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P P+ +++ D R + ++WT P GN+ I Y +Q + W + +I P
Sbjct: 930 PGPPQIVKIEDVWGRNVALTWTPPKDDGNAAITGYTIQKADKKSMEWLRVIEHIIEPVPH 989
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSE 155
T + N Y+ R+ +EN G SE
Sbjct: 990 TELVIGN-----EYYFRVFSENMCGLSE 1012
Score = 32.7 bits (71), Expect = 7.5
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYV 207
GPPQ V++E + +TW PP+ D N I GY +
Sbjct: 931 GPPQIVKIEDVWGRNVALTWTPPKDD-GNAAITGYTI 966
>BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein
protein.
Length = 868
Score = 68.1 bits (159), Expect = 2e-10
Identities = 85/396 (21%), Positives = 156/396 (39%), Gaps = 27/396 (6%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVT 337
E +P P +A SSQ + ++W P G IL GY + W D
Sbjct: 358 EALPKAPSAPAILSA-SSQGITLTWTAPRGPGSAHIL-GYLIERRKKGSNTWTAVND--- 412
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAAV 394
+ + T++ +R+ Y V A +G G P V+ P +++
Sbjct: 413 QPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTD 472
Query: 395 SSRNKILVSWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
S I +SW P + G GY + + + + H + +T + + R P
Sbjct: 473 RSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLR--PGE 530
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPA----RITSFSRNIVT-PWKENISLSCNKV 508
+ V+A G+ + + + T++ + V + S +++++T + + + +
Sbjct: 531 GYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFE 590
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTY 566
+P P TW +G+ L V+ DG L I + +DSG YT + + G+ EV +
Sbjct: 591 AMPMPEVTWLKDGLPLPKR-SVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGK-EVAH 648
Query: 567 TVEVKV---PPQPPILAVVDSYADSLHLQWSDQGDGGSPI-LGY-VINYKREHGDWEELQ 621
+ ++V P P + + ++ ++ +W D + L Y V HG W E
Sbjct: 649 SFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAA 708
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD 657
T+ L + G Y + A N +G P D
Sbjct: 709 DRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSD 744
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYADSLHLQWSDQGD-GGSPI 603
D G Y+ ++ + G + T++V P PP + V D + + L+W D GG +
Sbjct: 234 DCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTV 293
Query: 604 LGYVINYKRE-HGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVH- 660
YV+ ++ W ++ + A ++ ++ G +Y + A G G +
Sbjct: 294 ECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEI 353
Query: 661 AYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
+P P +++ ++ +T+ W G G IL ++IE R+ W V N
Sbjct: 354 LVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAV-ND 412
Query: 720 VQATERVFSVSGLTPAAHYQLRITA 744
ER ++V+ + Y+ R+TA
Sbjct: 413 QPVPERRWTVADVRQGCQYEFRVTA 437
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/172 (22%), Positives = 75/172 (43%), Gaps = 10/172 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
+P+ P ++ S+ I ++WT P G++ I+ Y+++ K+ +W + + +
Sbjct: 360 LPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERR 419
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSST 184
T A V+ Y R+ A G EP P + P G ++++V +S+T
Sbjct: 420 WTVADVRQ---GCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNT 476
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ ++W P D G+ YV + +S+S + G T T +G
Sbjct: 477 SITLSWAGP--DTQEGDEAQGYV-VELCSSDSLQWLPCHVGTVPVTTYTAKG 525
Score = 41.1 bits (92), Expect = 0.021
Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIIN-YIVQYKEAPESWPSTPQKV-IVPGSV 127
P + +N++V D+ + +I +SW P Y+V+ + +S P V VP V
Sbjct: 462 PGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSS-DSLQWLPCHVGTVP--V 518
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T+ + + L+P Y +R+ A N GQS+PS
Sbjct: 519 TTYTAKGLRPGEGYFVRVTAVNEGGQSQPS 548
Score = 34.3 bits (75), Expect = 2.4
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+SC G P P TW N LE + ++ +LTI DSG Y EN
Sbjct: 793 MSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTL 852
Query: 560 GRDEVTYTVEVKVP 573
G+ T T+ V P
Sbjct: 853 GQAVSTATLIVIEP 866
Score = 33.9 bits (74), Expect = 3.2
Identities = 31/142 (21%), Positives = 54/142 (38%), Gaps = 6/142 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV--TYAPVTDWYGNEDAVTK 338
D P P G ++ V + W PP G + + Y V A + W +A
Sbjct: 259 DKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTV-ECYVVERRQAGRSTWLKVGEAPAD 317
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ + R+YT + V AG+ + + + E +P AP+ +S
Sbjct: 318 STTFTDAHVEPGRKYT-FRVRAVTSEGAGEALESEEILV-APEALPKAPSAPAILSASSQ 375
Query: 399 KILVSWLPPSSPNGV-LVGYTL 419
I ++W P P ++GY +
Sbjct: 376 GITLTWTAPRGPGSAHILGYLI 397
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWT-QPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P+ P I + + T+ W P ++Y V + + W ++
Sbjct: 658 PQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIYT---- 713
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
++ + P YH R++A+N LG S+PS Q
Sbjct: 714 NRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQ 747
>AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein
protein.
Length = 868
Score = 68.1 bits (159), Expect = 2e-10
Identities = 85/396 (21%), Positives = 156/396 (39%), Gaps = 27/396 (6%)
Query: 280 EDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV--TDWYGNEDAVT 337
E +P P +A SSQ + ++W P G IL GY + W D
Sbjct: 358 EALPKAPSAPAILSA-SSQGITLTWTAPRGPGSAHIL-GYLIERRKKGSNTWTAVND--- 412
Query: 338 KQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP---VYCHTEEDVPSAPADIKAAV 394
+ + T++ +R+ Y V A +G G P V+ P +++
Sbjct: 413 QPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTD 472
Query: 395 SSRNKILVSWLPPSSPNG-VLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRA 453
S I +SW P + G GY + + + + H + +T + + R P
Sbjct: 473 RSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLR--PGE 530
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPA----RITSFSRNIVT-PWKENISLSCNKV 508
+ V+A G+ + + + T++ + V + S +++++T + + + +
Sbjct: 531 GYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFE 590
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT--LTISMTQSADSGNYTCSVENIHGRDEVTY 566
+P P TW +G+ L V+ DG L I + +DSG YT + + G+ EV +
Sbjct: 591 AMPMPEVTWLKDGLPLPKR-SVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGK-EVAH 648
Query: 567 TVEVKV---PPQPPILAVVDSYADSLHLQWSDQGDGGSPI-LGY-VINYKREHGDWEELQ 621
+ ++V P P + + ++ ++ +W D + L Y V HG W E
Sbjct: 649 SFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAA 708
Query: 622 VEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD 657
T+ L + G Y + A N +G P D
Sbjct: 709 DRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSD 744
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVKVPPQPP--ILAVVDSYADSLHLQWSDQGD-GGSPI 603
D G Y+ ++ + G + T++V P PP + V D + + L+W D GG +
Sbjct: 234 DCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTV 293
Query: 604 LGYVINYKRE-HGDWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVH- 660
YV+ ++ W ++ + A ++ ++ G +Y + A G G +
Sbjct: 294 ECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEI 353
Query: 661 AYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNS 719
+P P +++ ++ +T+ W G G IL ++IE R+ W V N
Sbjct: 354 LVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAV-ND 412
Query: 720 VQATERVFSVSGLTPAAHYQLRITA 744
ER ++V+ + Y+ R+TA
Sbjct: 413 QPVPERRWTVADVRQGCQYEFRVTA 437
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/172 (22%), Positives = 75/172 (43%), Gaps = 10/172 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQY-KEAPESWPSTPQKVIVPGS 126
+P+ P ++ S+ I ++WT P G++ I+ Y+++ K+ +W + + +
Sbjct: 360 LPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERR 419
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSST 184
T A V+ Y R+ A G EP P + P G ++++V +S+T
Sbjct: 420 WTVADVRQ---GCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNT 476
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ ++W P D G+ YV + +S+S + G T T +G
Sbjct: 477 SITLSWAGP--DTQEGDEAQGYV-VELCSSDSLQWLPCHVGTVPVTTYTAKG 525
Score = 41.1 bits (92), Expect = 0.021
Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIIN-YIVQYKEAPESWPSTPQKV-IVPGSV 127
P + +N++V D+ + +I +SW P Y+V+ + +S P V VP V
Sbjct: 462 PGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSS-DSLQWLPCHVGTVP--V 518
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS 157
T+ + + L+P Y +R+ A N GQS+PS
Sbjct: 519 TTYTAKGLRPGEGYFVRVTAVNEGGQSQPS 548
Score = 34.3 bits (75), Expect = 2.4
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE---STLRKNVSSDGTLTISMTQSADSGNYTCSVENIH 559
+SC G P P TW N LE + ++ +LTI DSG Y EN
Sbjct: 793 MSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTL 852
Query: 560 GRDEVTYTVEVKVP 573
G+ T T+ V P
Sbjct: 853 GQAVSTATLIVIEP 866
Score = 33.9 bits (74), Expect = 3.2
Identities = 31/142 (21%), Positives = 54/142 (38%), Gaps = 6/142 (4%)
Query: 281 DVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRV--TYAPVTDWYGNEDAVTK 338
D P P G ++ V + W PP G + + Y V A + W +A
Sbjct: 259 DKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTV-ECYVVERRQAGRSTWLKVGEAPAD 317
Query: 339 QISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRN 398
+ + R+YT + V AG+ + + + E +P AP+ +S
Sbjct: 318 STTFTDAHVEPGRKYT-FRVRAVTSEGAGEALESEEILV-APEALPKAPSAPAILSASSQ 375
Query: 399 KILVSWLPPSSPNGV-LVGYTL 419
I ++W P P ++GY +
Sbjct: 376 GITLTWTAPRGPGSAHILGYLI 397
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 6/94 (6%)
Query: 70 PEMPKNIRVIDQQSRTIQISWT-QPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
P+ P I + + T+ W P ++Y V + + W ++
Sbjct: 658 PQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIYT---- 713
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQ 161
++ + P YH R++A+N LG S+PS Q
Sbjct: 714 NRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQ 747
>BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine
kinase protein.
Length = 894
Score = 67.7 bits (158), Expect = 2e-10
Identities = 38/151 (25%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQKVI 122
+P+ P+N+ ++ +Q ++++WT +G P+ + +Q + + P P++ +
Sbjct: 224 LPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPL 283
Query: 123 VP-GSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
SV ++ +L P T YH+R+ + G S + + V T E VP GPP+++
Sbjct: 284 TSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISA- 342
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQ 210
++ ++ V W+ P+ L G +LGY + +Q
Sbjct: 343 TRNGSQAFVHWQEPRAPL-QGTLLGYRLAYQ 372
Score = 47.2 bits (107), Expect = 3e-04
Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 9/213 (4%)
Query: 163 TTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
T T V P+++ + ++ TEL V W P ++ + Q + S+ + I +
Sbjct: 218 TATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLT----HCTLQAVLSDDGMGIQA 273
Query: 223 GPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV 282
G T + A + L L H Y + V +S+ E V
Sbjct: 274 GEPDPPEEPLTSQ-ASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGV 332
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + SQ+ V W+ P G L GYR+ Y D +Q
Sbjct: 333 PLGPPENISATRNGSQAF-VHWQEP-RAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVT 390
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPV 375
L L G +N +V V A+TAAGDG + PV
Sbjct: 391 LE--LQGDGSVSNLTVCVAAYTAAGDGPWSLPV 421
>M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor
protein.
Length = 885
Score = 67.3 bits (157), Expect = 3e-10
Identities = 38/151 (25%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQKVI 122
+P+ P+N+ ++ +Q ++++WT +G P+ + +Q + + P P++ +
Sbjct: 224 LPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPL 283
Query: 123 VP-GSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
SV ++ +L P T YH+R+ + G S + + V T E VP GPP+++
Sbjct: 284 TSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPKNISA- 342
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQ 210
++ ++ V W+ P+ L G +LGY + +Q
Sbjct: 343 TRNGSQAFVHWQEPRAPL-QGTLLGYRLAYQ 372
Score = 49.2 bits (112), Expect = 8e-05
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 11/228 (4%)
Query: 163 TTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
T T V P+++ + ++ TEL V W P ++ + Q + S+ + I +
Sbjct: 218 TATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLT----HCTLQAVLSDDGMGIQA 273
Query: 223 GPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV 282
G T + A + L L H Y + V +S+ E V
Sbjct: 274 GEPDPPEEPLTSQ-ASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGV 332
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + SQ+ V W+ P G L GYR+ Y D +Q
Sbjct: 333 PLGPPKNISATRNGSQAF-VHWQEP-RAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVT 390
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDV--PSAPA 388
L L G +N +V V A+TAAGDG + PV V PS PA
Sbjct: 391 LE--LQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPVKEPSTPA 436
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4077 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4136
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4170
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3102 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3156
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3157 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 3216
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3217 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3245
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3135
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 3136 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 3194
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3195 SDSLEVRILSGGSK 3208
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2752 GEDELDFDVNIQVPP 2766
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3711
Query: 573 PP 574
PP
Sbjct: 3712 PP 3713
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+ TW +G V L +++R +S L + T D+G
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAG 2453
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2454 QYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3606 GDDDKEYLVRVHVPP 3620
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3322 TNPAGEEDRIFNLNVYVTP 3340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3769
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3804
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4355 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4415 GDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4114 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4167
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4227
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4228 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 4334 VGFVKAIGFVYVKEPP 4349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3845 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3896
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3897 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3952
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3953 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 50.0 bits (114), Expect = 5e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2855 GEDSLQYDVRVLVPP 2869
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGT-LTISMTQ 544
S S N+V N + L C G+PAP+ TW +G + S V S G L ++ Q
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2303 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPP 2384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4065 GTALGKIKLNVQVPP 4079
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2494 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2554 SPAGHKSRSFSLNVFVSP 2571
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3514 EVSKHFILKVLEPP 3527
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4457 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4517 SVLVRVPVIVQV 4528
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2273
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2274 VAGTAKKEYNLQVYIRP 2290
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2654 EMIKHYEVKVYIPP 2667
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 1115 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIT 1174
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 1175 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 1208
Score = 64.9 bits (151), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 140 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 194
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 195 EREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQH 254
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 255 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 632 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 689
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 690 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 749
Query: 573 PP 574
PP
Sbjct: 750 PP 751
Score = 60.1 bits (139), Expect = 4e-08
Identities = 38/134 (28%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 114 SVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 173
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ N+KR E+
Sbjct: 174 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNHKRIEN 232
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 233 SDSLEVRILSGGSK 246
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 584 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 643
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 644 GDDDKEYLVRVHVPP 658
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 300 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 359
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 360 TNPAGEEDRIFNLNVYVTP 378
Score = 53.2 bits (122), Expect = 5e-06
Identities = 47/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L T P A H ++A+ G + +TV V
Sbjct: 1152 KDGRAIVESIRQRVLSSGSLQI-TFVQPGDAGHYTCMAANVA-GSSSTSTKLTV----HV 1205
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 1206 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 1265
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 1266 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 1298
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 748 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 807
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 808 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 842
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 1313 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 1371
Query: 559 HGRDEVTYTVEVKVPP 574
G + V VK PP
Sbjct: 1372 VGFVKAIGFVYVKEPP 1387
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 823 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 882
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 883 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 934
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 935 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 990
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 991 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 1026
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/81 (32%), Positives = 40/81 (49%)
Query: 494 VTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTC 553
+ P N L+C G P P W GV +E + R +G+L I T + D+G+YTC
Sbjct: 1398 IEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTC 1457
Query: 554 SVENIHGRDEVTYTVEVKVPP 574
N G E + ++ ++ PP
Sbjct: 1458 VATNEAGVVERSMSLTLQSPP 1478
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 61
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 62 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 94
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 1043 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 1102
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 1103 GTALGKIKLNVQVPP 1117
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 387 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 446
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 447 AVYTCVASNRAGVDNKHYNLQVFAPP 472
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 492 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 551
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 552 EVSKHFILKVLEPP 565
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 1495 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 1554
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 1555 SVLVRVPVIVQV 1566
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/94 (34%), Positives = 50/94 (53%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTIS 541
VP I+ + V + I+LSC G+P P TW +G + ++R+ V S G+L I+
Sbjct: 4078 VPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIA 4137
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
Q D+G+YTC N+ G + + V VPP+
Sbjct: 4138 FVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR 4171
Score = 66.5 bits (155), Expect = 5e-10
Identities = 40/134 (29%), Positives = 68/134 (50%), Gaps = 6/134 (4%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENI 558
++SL C VP P TW NG + + + +DG L I + +D+G Y C N+
Sbjct: 3077 SVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINV 3136
Query: 559 HGRDEVTYTVEVKVPPQ---PPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EH 614
GRD+ + + V VPP P +V++ ++ + L G P + ++ NYKR E+
Sbjct: 3137 AGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGI-PPPTIAWLKNYKRIEN 3195
Query: 615 GDWEELQVEAGTSE 628
D E+++ +G S+
Sbjct: 3196 SDSLEVRILSGGSK 3209
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 9/149 (6%)
Query: 430 EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSF 489
E TH +L+ + H ++ T Q+ A G + + V VP I
Sbjct: 3103 ESTHVEILADGQMLH-IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY----VPPSIEGP 3157
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLEST--LRKNVSSDGT-LTISMTQS 545
R ++ N ++L+C+ G+P P W N +E++ L + S G+ L I+ +Q
Sbjct: 3158 EREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQH 3217
Query: 546 ADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+DSGNYTC N+ G+ + Y + ++VPP
Sbjct: 3218 SDSGNYTCIASNMEGKAQKYYFLSIQVPP 3246
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 1169 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 1228
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 1229 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 1262
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
++L C +P+ + +W +G L+S N++++G TL I Q +D+G YTC NI
Sbjct: 2693 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2752
Query: 560 GRDEVTYTVEVKVPP 574
G DE+ + V ++VPP
Sbjct: 2753 GEDELDFDVNIQVPP 2767
Score = 60.9 bits (141), Expect = 2e-08
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 3/122 (2%)
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
T ++ AS+ G+ + +V V ++ T R+I ++L C VP P
Sbjct: 3595 TGRYTCLASSPAGDDDKEYLVRVHVPPNIAG--TDEPRDITVLRNRQVTLECKSDAVPPP 3652
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
TW NG L++T R + S G L I+ D+ NYTC NI G+ + + V V
Sbjct: 3653 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV 3712
Query: 573 PP 574
PP
Sbjct: 3713 PP 3714
Score = 59.3 bits (137), Expect = 8e-08
Identities = 31/85 (36%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQSADSG 549
NI K ++SL+C G+P P+TTW +G V L +++R +S L + T D+G
Sbjct: 2396 NISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVR-ILSGGRMLRLMQTTMEDAG 2454
Query: 550 NYTCSVENIHGRDEVTYTVEVKVPP 574
YTC V N G + + + V VPP
Sbjct: 2455 QYTCVVRNAAGEERKIFGLSVLVPP 2479
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L CN G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 1658 SLTLECNAAGNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 1718 AGEKEIKYEVDVLVPP 1733
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/93 (29%), Positives = 43/93 (46%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISM 542
P ++T +N +S+ C+ G P P WT+N + + + R ++SDGTL I
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKN 670
Query: 543 TQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
D+G Y C N G D+ T+ P+
Sbjct: 671 AAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
+ L+C G+PAP TW +G L T + G L IS Q D+G YTC +
Sbjct: 3547 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3606
Query: 560 GRDEVTYTVEVKVPP 574
G D+ Y V V VPP
Sbjct: 3607 GDDDKEYLVRVHVPP 3621
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 1565 IKLECKTRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 1624
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 1625 GTAEKSFHVDVYVPP 1639
Score = 53.6 bits (123), Expect = 4e-06
Identities = 28/76 (36%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E + LSC G+P P TWT N + + +V+ L I DSG Y C+ EN
Sbjct: 4276 EQLRLSCKATGIPLPKLTWTFNNNIIPAHF-DSVNGHSELVIERVSKEDSGTYVCTAENS 4334
Query: 559 HGRDEVTYTVEVKVPP 574
G + T V VK PP
Sbjct: 4335 VGFVKATGFVYVKEPP 4350
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES--TLRKNVSSDG-TLTISMTQSADSGNYTCSV 555
EN+ L CN G+P P W +G + S T R VS++G TL I ++D+G YTC
Sbjct: 3263 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3322
Query: 556 ENIHGRDEVTYTVEVKVPP 574
N G ++ + + V V P
Sbjct: 3323 TNPAGEEDRIFNLNVYVTP 3341
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 481 SVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-LRKNVSSDGTLT 539
+VP I +++V ++ L C GVP P TW +G L R ++ +G L
Sbjct: 3711 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH 3770
Query: 540 ISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I D+G Y C N G D ++V VPP
Sbjct: 3771 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPP 3805
Score = 52.0 bits (119), Expect = 1e-05
Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 2102 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 2161
Query: 541 SMTQSADSGNYTCSVENIHGRDE-VTYTVEVKVPP 574
Q D+G YTC N+ G+ E Y V + VPP
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWVPP 2196
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/86 (31%), Positives = 42/86 (48%)
Query: 489 FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADS 548
+ N + P N L+C G P P W GV +E + R +G+L I T + D+
Sbjct: 4356 YPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4415
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
G+YTC N G E + ++ ++ PP
Sbjct: 4416 GDYTCVATNEAGVVERSMSLTLQSPP 4441
Score = 51.6 bits (118), Expect = 2e-05
Identities = 46/153 (30%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 425 EDGRE--EGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSV 482
+DGR E +R+LS +L + P A H ++A+ G + +TV V
Sbjct: 4115 KDGRAIVESIRQRVLSSGSLQIAFVQ-PGDAGHYTCMAANVA-GSSSTSTKLTV----HV 4168
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTIS 541
P RI S + L C G+P PA W + V L + L K + G L +
Sbjct: 4169 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILE 4228
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
DSG YTC N G D T ++ V V P
Sbjct: 4229 NVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4261
Score = 50.8 bits (116), Expect = 3e-05
Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
S S N+V N + L C G+PAP+ TW +G V S + +S L ++ TQ
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQ 2074
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 2104
Score = 50.8 bits (116), Expect = 3e-05
Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 15/216 (6%)
Query: 362 AFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKIL--VSWLPPSSPNGVLVGYTL 419
A AAG R + H + P ++ V+ + + + +P S N G+ L
Sbjct: 3786 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3845
Query: 420 YMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS 479
+ + R+LS +L + AT++ V+ G+ + T +TV
Sbjct: 3846 NVD------QNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGA--GDDKRTVDLTVQVP 3897
Query: 480 DSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTL 538
S+ T F +VT + ++C GVP P+ WT NG+ L + S G +
Sbjct: 3898 PSIADEPTDF---LVTKHAPAV-ITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI 3953
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
I TQ +G YTC N G T+ V PP
Sbjct: 3954 EILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3989
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIH 559
ISL C P P TW +G L S+ + + G L I + D+G YTC N
Sbjct: 2796 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2855
Query: 560 GRDEVTYTVEVKVPP 574
G D + Y V V VPP
Sbjct: 2856 GEDSLQYDVRVLVPP 2870
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV-GVPAPATTWTM 519
A + G+ ++ VTV + I+ N++ + ++L C + G P P W
Sbjct: 869 AENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG--QQLTLPCTLLAGNPIPERRWIK 926
Query: 520 NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N L V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 927 NSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 493 IVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNY 551
IVT K +ISL C G+P P TW +G L + +G L + +D+G Y
Sbjct: 2304 IVTRGK-SISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2362
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N+ G + Y + V PP
Sbjct: 2363 VCVAVNVAGMTDKKYDLSVHAPP 2385
Score = 48.4 bits (110), Expect = 1e-04
Identities = 64/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VCAFT-AAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C T AG+ +A +
Sbjct: 1109 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 1222 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ +GTL I+ D+G Y
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEEGTLLVIASVTPYDNGEY 1336
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPP 1359
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/115 (27%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMN 520
A GE V VL + + + ++ + C G PAP +W +
Sbjct: 2851 AVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKD 2910
Query: 521 GVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
G L E K +S+ L I TQ D G Y C EN G + + + V VPP
Sbjct: 2911 GQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2965
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTIS 541
P+ I S N+ ISL+C G P P +W N ++ + G TL I
Sbjct: 2965 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQII 3024
Query: 542 MTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+ +D G YTC N G + +++ V VPP
Sbjct: 3025 RAKVSDGGEYTCIAINXAGESKKKFSLTVYVPP 3057
Score = 46.8 bits (106), Expect = 4e-04
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKN-VSSDGTLTISMTQSADSGNYTCSVENIH 559
I L C G P+P TW G+ + ++ R + V G L IS D+G Y C +N
Sbjct: 4006 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4065
Query: 560 GRDEVTYTVEVKVPP 574
G + V+VPP
Sbjct: 4066 GTALGKIKLNVQVPP 4080
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 498 KENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVE 556
K++++L+C G P P TW +G L+ ++ S G L I+ Q +G YTC
Sbjct: 2495 KQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2554
Query: 557 NIHGRDEVTYTVEVKVPP 574
+ G ++++ V V P
Sbjct: 2555 SPAGHKSRSFSLNVFVSP 2572
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 1439 TSQKYFNIDVLVPP 1452
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 490 SRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADS 548
+ ++T +I++ C G P P W NG+ L S+ + +++ + I Q +D
Sbjct: 3350 AEKLMTYVDTSINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3409
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP 574
YTC N G D Y ++V PP
Sbjct: 3410 AVYTCVASNRAGVDNKHYNLQVFAPP 3435
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
S++C G PAP+ W +G L VS+ G L + ++ DSG YTC N G
Sbjct: 3455 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3514
Query: 561 RDEVTYTVEVKVPP 574
+ ++V PP
Sbjct: 3515 EVSKHFILKVLEPP 3528
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/72 (33%), Positives = 34/72 (47%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
I L+C G P P TW+ G + R NV S+ +L I+ Q D+ + C N+ G
Sbjct: 4458 IILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMG 4517
Query: 561 RDEVTYTVEVKV 572
V V V+V
Sbjct: 4518 SVLVRVPVIVQV 4529
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 501 ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVEN 557
ISL C G+P P W G V +S R + S G L IS+ + +D+ Y+C N
Sbjct: 2215 ISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN 2274
Query: 558 IHGRDEVTYTVEVKVPP 574
+ G + Y ++V + P
Sbjct: 2275 VAGTAKKEYNLQVYIRP 2291
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN 1154
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 1155 IAGNVTQAVKLNVHVPPK 1172
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 1824 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 1881
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDG-TLTISMTQSADSGNYTCSVENIHG 560
SL C P TW +G LES + G TL I Q ++G Y+C N G
Sbjct: 2595 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2654
Query: 561 RDEVTYTVEVKVPP 574
Y V+V +PP
Sbjct: 2655 EMIKHYEVKVYIPP 2668
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1997
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1998 GATELFYSLQVHVAP 2012
Score = 41.5 bits (93), Expect = 0.016
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 503 LSCNKVGVPAPATTWTMNGVGLE-STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGR 561
+ C G+P P W + L ST G L I TQ D+G+YTC N GR
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 562 DEVTYTVEVKVPP 574
T++V PP
Sbjct: 781 ATGKITLDVGSPP 793
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + + +SG Y C+ N
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTA 1057
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 1058 GYAKRKVQLTVYVR 1071
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 1811
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 1812 GDHKKEFEVTVHVPP 1826
Score = 37.1 bits (82), Expect = 0.35
Identities = 20/90 (22%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + + +++L C G P P W +G + L + + L + +
Sbjct: 1457 TNFPKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 1516
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Score = 32.3 bits (70), Expect = 9.9
Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 500 NISLSCNKVGVPAPATTWT-MNGVGLESTLRKNVSS-----DGTLTISMTQSADSGNYTC 553
N++L C G P P W ++ + + S +VSS G L I ++D G Y C
Sbjct: 809 NVTLPCYVQGYPEPTIKWRRLDNMPIFSR-PFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 554 SVENIHGR--DEVTYTVEVKVPP 574
EN G+ E T TV V P
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAP 890
>AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein.
Length = 1685
Score = 65.7 bits (153), Expect = 9e-10
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 17/194 (8%)
Query: 571 KVPPQPPI-LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR----EHGDWEELQVEA 624
+ PP PP + ++S+ DS+ L W GG+ I GY +NY+ G W E V+A
Sbjct: 931 RAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKA 990
Query: 625 GTSE-HVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY--TKGTVPVK-PKHSQMIT-- 678
+ E + + NL YQ + A N G G P + + + T+ V P HS +
Sbjct: 991 VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYRE--MSQPQWRLVSNSVQATERVF-SVSGLTPA 735
+ V W G + + ++ +E + QWR ++ + A + V+ V GL
Sbjct: 1051 RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA--AIKNVYLKVRGLKEG 1108
Query: 736 AHYQLRITAHNNAG 749
Y R+ A N AG
Sbjct: 1109 VSYVFRVRAINQAG 1122
Score = 60.5 bits (140), Expect = 3e-08
Identities = 64/290 (22%), Positives = 116/290 (40%), Gaps = 17/290 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQI 340
P PP + C S+ + W+ P G + GY V Y V D + +A K +
Sbjct: 933 PPSPPCDITCLESFRDSMVLGWKQPDKTG-GAEITGYYVNYREVIDGVPGKWREANVKAV 991
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSS 396
S +S L+ Y V A AG G +A C E+ VP P +K +
Sbjct: 992 SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVR 1051
Query: 397 RNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSH---ETSRSPPRA 453
++ +++ W PP V T Y +++ + + R L+ + + + +
Sbjct: 1052 KDSLVLQWKPPVHSGRTPV--TGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGV 1109
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
++ F V A + G G+ + + + +++ P N+ +++ C+K+ P
Sbjct: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRPG-TKEVVVNVDDDGVISLNFECDKM-TPKS 1167
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHG 560
+W+ + V E + R V S G +T D G Y+C V + G
Sbjct: 1168 EFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
Score = 58.8 bits (136), Expect = 1e-07
Identities = 87/413 (21%), Positives = 156/413 (37%), Gaps = 32/413 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP P ++ V + + +SW P G+ I+ ++ + + E+W ++ P
Sbjct: 637 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTEL--PVKS 694
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSGPPQDVRVEAKSST 184
++ +L SY R+ N G EPS+ +VT ++P P + + + T
Sbjct: 695 PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK-IIPSRNTDT 753
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++V+WE +D ++GYY+ S + P V+G SR
Sbjct: 754 SVVVSWE-ESKDA--KELVGYYIEASVAGSGKWEPCNNNP---------VKG-----SRF 796
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
T GL +Y V+A N+ ++ C ALS + ++
Sbjct: 797 TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT- 855
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-HTTLSGLRRYTNYSVTVCAF 363
RGR + N+ ++ L T +S + +T
Sbjct: 856 ---ASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
Query: 364 TAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-Y 420
AA G ++ P+ T+ PS P DI S R+ +++ W P G + GY + Y
Sbjct: 913 KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNY 972
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
VI+ + + + S +++ S +QF V+A G G + V
Sbjct: 973 REVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAV 1025
Score = 56.4 bits (130), Expect = 5e-07
Identities = 144/646 (22%), Positives = 219/646 (33%), Gaps = 63/646 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P P +++ ++ I ISW QP G SPI+ Y + E +SW P
Sbjct: 510 PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCND---TPVKF 566
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
V L SY R+ A N++G PS+ + + R A + ++I
Sbjct: 567 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQII 626
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG-----GASYTVRTVEGAGTAR- 241
VT E P + G V E + VL PG G Y V E AGT
Sbjct: 627 VTEEEPSEGIVPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCE-AGTENW 683
Query: 242 -----------SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PG 288
R L L + +Y V+ NS + D +P PG
Sbjct: 684 QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPG 743
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS 348
+ + + SV VSWE L GY + A V E + G T
Sbjct: 744 KIIPSRNTDTSVVVSWEESKDAKE---LVGYYIE-ASVAGSGKWEPCNNNPVKGSRFTCH 799
Query: 349 GLRRYTNYSVTVCAFTAAG--------DGVRA-APVYCHTEEDVPSAPADIKAAVSSRNK 399
GL +Y V A AAG + + A + DV A +D +++
Sbjct: 800 GLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRG 859
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
+ PP+ L+G + + + S E PP+
Sbjct: 860 RVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGK 919
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKV----------- 508
S S L + + R P D + SF ++V WK+ ++
Sbjct: 920 SKSDPL-KKKTDRAPPSPPCDI--TCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVI 976
Query: 509 -GVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYT 567
GVP + V E+ N+ + + +G S + + E +T
Sbjct: 977 DGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCE-EWT 1035
Query: 568 VEVKVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKR---EHGDWEELQVE 623
+ V PP L + DSL LQW G +P+ GY ++ K + W L
Sbjct: 1036 IAVPGPPHS--LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA 1093
Query: 624 AGTSEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
A + ++ + L G Y + A N+ G G P D+ T P
Sbjct: 1094 AIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRP 1139
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 484 ARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLES----TLRKNVSSDGTL 538
AR+ ++VT + + ++L+CN G P P +W N L S L+
Sbjct: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYF 1631
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
TI+ +ADSG Y V+N +G + +TV V +P + +A ++S
Sbjct: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1677
Score = 46.4 bits (105), Expect = 6e-04
Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 499 ENISLSCNKVGVPA-----PATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGN 550
E +SL C V P P W NGV L + G TLT S D G
Sbjct: 420 ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
Query: 551 YTCSVENIHGRDEVTYTV-------EVKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGS 601
YT V ++ + V E++ P P+ + +++ D + + W DGGS
Sbjct: 480 YTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGS 539
Query: 602 PILGYVINYKREHG--DWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
PILGY I+ K E G W + + + L G Y + A N++G G P
Sbjct: 540 PILGYFID-KCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
Score = 39.5 bits (88), Expect = 0.065
Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP---ESWPSTPQKVIVP 124
VP P +++ + + ++ + W P ++G +P+ Y V KEA + W + I
Sbjct: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI-- 1095
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
V+ L+ SY R+ A N+ G +PS E P V V+
Sbjct: 1096 -KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
Score = 35.9 bits (79), Expect = 0.80
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 495 TPW-KENISLSCNKVGVPAPATTWTMNGV--GLESTLRKNV--SSDG--TLTISMTQSAD 547
T W KEN+ L C+ G P P TW N V + + K + S G TL I+ D
Sbjct: 287 TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINACDFED 346
Query: 548 SGNYTCSVENIHGRDEVTYTVEVK 571
+ Y S N+ G +V VK
Sbjct: 347 TAQYRASAMNVKGELSAYASVVVK 370
Score = 32.7 bits (71), Expect = 7.5
Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGY 417
E P+AP D+K ++++ I++SW P+ G ++GY
Sbjct: 507 EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
Score = 32.3 bits (70), Expect = 9.9
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 663 TKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQ 721
++G VP P + + V + W G GI+YFV E E W+ V+ +
Sbjct: 633 SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELP 691
Query: 722 ATERVFSVSGLTPAAHYQLRITAHNNAG 749
F++ L Y R+ N+AG
Sbjct: 692 VKSPRFALFDLAEGKSYCFRVRCSNSAG 719
>X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA for
tyrosine kinase receptor. ).
Length = 894
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/151 (24%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQKVI 122
+P+ P+N+ ++ +Q ++++WT +G P+ + +Q + + P P++ +
Sbjct: 224 LPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPL 283
Query: 123 VP-GSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
SV ++ +L P YH+R+ + G S + + V T E VP GPP+++
Sbjct: 284 TSQASVPPHQLRLGSLHPHPPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISA- 342
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQ 210
++ ++ V W+ P+ L G +LGY + +Q
Sbjct: 343 TRNGSQAFVHWQEPRAPL-QGTLLGYRLAYQ 372
Score = 46.8 bits (106), Expect = 4e-04
Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 9/213 (4%)
Query: 163 TTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
T T V P+++ + ++ TEL V W P ++ + Q + S+ + I +
Sbjct: 218 TATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLT----HCTLQAVLSDDGMGIQA 273
Query: 223 GPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV 282
G T + A + L L H Y + V +S+ E V
Sbjct: 274 GEPDPPEEPLTSQ-ASVPPHQLRLGSLHPHPPYHIRVACTSSQGPSSWTHWLPVETPEGV 332
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + SQ+ V W+ P G L GYR+ Y D +Q
Sbjct: 333 PLGPPENISATRNGSQAF-VHWQEP-RAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVT 390
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPV 375
L L G +N +V V A+TAAGDG + PV
Sbjct: 391 LE--LQGDGSVSNLTVCVAAYTAAGDGPWSLPV 421
>S65125-1|AAB20305.1| 894|Homo sapiens UFO protein.
Length = 894
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/151 (24%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESW------PSTPQKVI 122
+P+ P+N+ ++ +Q ++++WT +G P+ + +Q + + P P++ +
Sbjct: 224 LPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPL 283
Query: 123 VP-GSVTSASVQ--NLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
SV ++ +L P YH+R+ + G S + + V T E VP GPP+++
Sbjct: 284 TSQASVPPHQLRLGSLHPHPPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISA- 342
Query: 180 AKSSTELIVTWEPPQRDLWNGNILGYYVGFQ 210
++ ++ V W+ P+ L G +LGY + +Q
Sbjct: 343 TRNGSQAFVHWQEPRAPL-QGTLLGYRLAYQ 372
Score = 46.8 bits (106), Expect = 4e-04
Identities = 55/213 (25%), Positives = 82/213 (38%), Gaps = 9/213 (4%)
Query: 163 TTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIAS 222
T T V P+++ + ++ TEL V W P ++ + Q + S+ + I +
Sbjct: 218 TATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLT----HCTLQAVLSDDGMGIQA 273
Query: 223 GPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDV 282
G T + A + L L H Y + V +S+ E V
Sbjct: 274 GEPDPPEEPLTSQ-ASVPPHQLRLGSLHPHPPYHIRVACTSSQGPSSWTHWLPVETPEGV 332
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISG 342
P PP + SQ+ V W+ P G L GYR+ Y D +Q
Sbjct: 333 PLGPPENISATRNGSQAF-VHWQEP-RAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVT 390
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPV 375
L L G +N +V V A+TAAGDG + PV
Sbjct: 391 LE--LQGDGSVSNLTVCVAAYTAAGDGPWSLPV 421
>AL391822-9|CAI14665.1| 297|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 297
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNG 412
Y Y + V A G G V ++ ED+PSAP + + I + W P PNG
Sbjct: 25 YVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNG 84
Query: 413 VLVGYTLYMSVIEDGREEGTH-KRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
+++GYTL V +G + G SP+ R+ P + ++F +SA T++G GEA
Sbjct: 85 IMIGYTL-KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA 142
Score = 40.7 bits (91), Expect = 0.028
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
Query: 141 YHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
Y +R+ AEN G+ + V + E++PS P+ RV + + + W+ P+ NG
Sbjct: 28 YEIRVQAENDFGKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPEHP--NG 84
Query: 201 NILGY---YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
++GY YV F ++ P +TV+ + +R R TLS
Sbjct: 85 IMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTD--PVSRYRFTLS 132
Score = 38.3 bits (85), Expect = 0.15
Identities = 27/111 (24%), Positives = 41/111 (36%), Gaps = 7/111 (6%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
IG +P P+ RV TI + W P N +I Y ++Y +
Sbjct: 48 IGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE 107
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP 172
+ T +VQ P + Y + A ++G E TEE P+ P
Sbjct: 108 NFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGE-------AVTEESPAPP 151
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS-DGTLTI 540
VP +I +++ + + + CN G P P TW+ G + +VS+ DGTL+I
Sbjct: 240 VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSI 299
Query: 541 SMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC NI G DE T+ V+ PP
Sbjct: 300 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPP 333
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENI 558
+++L C G P+P TW +GV +++ + + G L I Q D G Y C ++
Sbjct: 729 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 788
Query: 559 HGRDEVTYTVEVKVPP 574
G E+ Y V+V VPP
Sbjct: 789 AGEKEIKYEVDVLVPP 804
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/75 (38%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
I L C G+P PA TW +G + S+ + G L I Q +DS YTC V N+
Sbjct: 636 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVA 695
Query: 560 GRDEVTYTVEVKVPP 574
G E ++ V+V VPP
Sbjct: 696 GTAEKSFHVDVYVPP 710
Score = 50.4 bits (115), Expect = 3e-05
Identities = 65/263 (24%), Positives = 94/263 (35%), Gaps = 25/263 (9%)
Query: 325 PVTDWYGNEDAVTKQISGLHTTL-SGLRRYTNYSVT-----VC-AFTAAGDGVRAAPVYC 377
P+ W E + S HT L SG + T + +C A AG+ +A +
Sbjct: 180 PIITW-AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAVKLNV 238
Query: 378 HTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRML 437
H + P +K V R I P + G + + +G H
Sbjct: 239 HVPPKIQRGPKHLKVQVGQRVDI------PCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 292
Query: 438 SPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPS--DSVPARITSFSRNIVT 495
TLS + + + + E E T V P+ D P T+F +
Sbjct: 293 PDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 352
Query: 496 PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRK---NVSSDGTL-TISMTQSADSGNY 551
+ I C G P P W NG E T R+ ++ DGTL I+ D+G Y
Sbjct: 353 ---QRIEFPCPAKGTPKPTIKWLHNG--RELTGREPGISILEDGTLLVIASVTPYDNGEY 407
Query: 552 TCSVENIHGRDEVTYTVEVKVPP 574
C N G E Y ++V VPP
Sbjct: 408 ICVAVNEAGTTERKYNLKVHVPP 430
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 488 SFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
S S N+V N + L C G+PAP+ TW +G V S + +S L ++ Q
Sbjct: 1086 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 1145
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
+D+G YTC N G + + V VPP
Sbjct: 1146 ISDTGRYTCVAVNAAGEKQRDIDLRVYVPP 1175
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 502 SLSCNKVGVPAPATTWTMNGVGL-ESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+L C G P+P W + V + ES+ + V++ L + D+G Y+C NI G
Sbjct: 450 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGRILKLFRATPEDAGRYSCKAINIAG 509
Query: 561 RDEVTYTVEVKVPP 574
+ + ++V VPP
Sbjct: 510 TSQKYFNIDVLVPP 523
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Query: 482 VPARITS--FSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV---SSDG 536
VP I S S +V +K ++L C G+P P+ TW + + +T + N+ SS
Sbjct: 895 VPPTIKSSGLSERVVVKYKP-VALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGR 952
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L I+ T D+G YTC N G + + V PP
Sbjct: 953 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 990
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 482 VPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD-GTLTI 540
VP I +N+ + + L C +P P TW +G L ++S + L I
Sbjct: 1173 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKI 1232
Query: 541 SMTQSADSGNYTCSVENIHG 560
Q D+G YTC N+ G
Sbjct: 1233 EDAQVQDTGRYTCEATNVAG 1252
Score = 42.7 bits (96), Expect = 0.007
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLES-TLRKNVSSDGTLTISMTQSADSGNYTCSVEN 557
E ++L C +P P TW + + R G++ I+ T+++DSG Y C N
Sbjct: 166 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAIN 225
Query: 558 IHGRDEVTYTVEVKVPPQ 575
I G + V VPP+
Sbjct: 226 IAGNVTQAVKLNVHVPPK 243
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLT-ISMTQSADSGNYTCSVENIH 559
+ L C G P P TW + L + + G + I Q +D+G Y C N
Sbjct: 1009 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSA 1068
Query: 560 GRDEVTYTVEVKVPP 574
G E+ Y+++V V P
Sbjct: 1069 GATELFYSLQVHVAP 1083
Score = 39.5 bits (88), Expect = 0.065
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRK-NVSSDGTLTISMTQSADSGNYTCSVENIH 559
++L C G P P+ W+ G + ++ K + +DG+L + +SG Y C+ N
Sbjct: 69 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 128
Query: 560 G--RDEVTYTVEVK 571
G + +V TV V+
Sbjct: 129 GYAKRKVQLTVYVR 142
Score = 39.1 bits (87), Expect = 0.086
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-LTISMTQSADSGNYTCSVENIH 559
+ L C+ G P P W +G ++ + +G L I+ Q +++G Y C N
Sbjct: 823 LELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTA 882
Query: 560 GRDEVTYTVEVKVPP 574
G + + V V VPP
Sbjct: 883 GDHKEEFEVTVHVPP 897
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/43 (44%), Positives = 23/43 (53%)
Query: 532 VSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
V SDG+L I Q D G YTC N+ G + T +V V V P
Sbjct: 10 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLP 52
Score = 36.3 bits (80), Expect = 0.61
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 487 TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDGTLTISMTQ 544
T+F + +++L C G P P W +G + L + + L + +
Sbjct: 528 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR 587
Query: 545 SADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
D G Y C+V N G+ + + +PP
Sbjct: 588 RNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 617
>M10905-1|AAA52462.1| 793|Homo sapiens FN1 protein.
Length = 793
Score = 63.7 bits (148), Expect = 3e-09
Identities = 80/349 (22%), Positives = 143/349 (40%), Gaps = 46/349 (13%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVP-GSVTS 129
+ PK + D +I+I+W P + Y V Y +PE + P G +
Sbjct: 40 DRPKGLAFTDVDVDSIKIAWESP---QGQVSRYRVTYS-SPED--GIHELFPAPDGEEDT 93
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
A +Q L+P + Y + ++A L SQP+ T + +P+ P D++ + T L
Sbjct: 94 AELQGLRPGSEYTVSVVA---LHDDMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQ 148
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W PP N + GY V T +GP ++ + A + S +SGL
Sbjct: 149 WTPP-----NVQLTGYRV-------RVTPKEKTGP------MKEINLAPDS-SSVVVSGL 189
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
Y V V A +E+V PP + + ++ +SW
Sbjct: 190 MVATKYEVSVYALKD-TLTSRPAQGVVTTLENVS--PPRRARVTDATETTITISW----- 241
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDG 369
R + + G++V P + + + T++GL+ T+Y + + +T D
Sbjct: 242 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYL--YT-LNDN 296
Query: 370 VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSP-NGVLVGY 417
R++PV + AP++++ ++ N +LVSW PP + G ++ Y
Sbjct: 297 ARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY 344
Score = 60.1 bits (139), Expect = 4e-08
Identities = 98/414 (23%), Positives = 160/414 (38%), Gaps = 40/414 (9%)
Query: 241 RSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSV 300
++ T+ GLQ Y V V A N ++ P L + S+
Sbjct: 1 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVDSI 55
Query: 301 RVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT-LSGLRRYTNYSVT 359
+++WE P G + YRVTY+ D G + T L GLR + Y+V+
Sbjct: 56 KIAWESP-----QGQVSRYRVTYSSPED--GIHELFPAPDGEEDTAELQGLRPGSEYTVS 108
Query: 360 VCAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTL 419
V A D + + P+ +P AP D+K + + W P PN L GY +
Sbjct: 109 VVALH---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTP---PNVQLTGYRV 161
Query: 420 YMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQFWVSA-STRLGEGEATRVVTVL 477
++ E + G K + L+P + S S ++ V A L A VVT L
Sbjct: 162 RVTPKE---KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 218
Query: 478 PSDSVP--ARITSFSRNIVT-PWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSS 534
+ S P AR+T + +T W+ PA T ++ T++ +V S
Sbjct: 219 ENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT----PIQRTIKPDVRS 274
Query: 535 DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWS 594
T+T + D Y ++ + V + P L + + +SL + W
Sbjct: 275 -YTIT-GLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQ 331
Query: 595 DQGDGGSPILGYVINYKREHGDWEEL--QVEAGTSEHVLPNLWCGTRYQLYITA 646
+ I GY+I Y++ E+ + G +E + L GT Y +Y+ A
Sbjct: 332 PP---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 382
Score = 53.2 bits (122), Expect = 5e-06
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 42/302 (13%)
Query: 62 IGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKV 121
IG+ S +P P +++ ++ WT P N + Y V+ ++ P
Sbjct: 122 IGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGPMKEIN- 176
Query: 122 IVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAK 181
+ P S +S V L AT Y + + A S P+Q V VTT E V PP+ RV
Sbjct: 177 LAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDA 232
Query: 182 SSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTAR 241
+ T + ++W I G+ V N + + P SYT+
Sbjct: 233 TETTITISWRTKTE-----TITGFQVDAVPANGQTPIQRTIKPDVRSYTI---------- 277
Query: 242 SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVR 301
+GLQ Y + + N ++ P L+ A + S+
Sbjct: 278 -----TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID-----APSNLRFLATTPNSLL 327
Query: 302 VSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-HTTLSGLRRYTNYSVTV 360
VSW+PP R + GY + Y + V + G+ T++GL T Y++ V
Sbjct: 328 VSWQPPRAR-----ITGYIIKYEKPGS--PPREVVPRPRPGVTEATITGLEPGTEYTIYV 380
Query: 361 CA 362
A
Sbjct: 381 IA 382
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 13/102 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPG---SV 127
+ P N+R + ++ +SW P A I YI++Y++ P +P + +VP V
Sbjct: 311 DAPSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEK-----PGSPPREVVPRPRPGV 362
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVP 169
T A++ L+P T Y + +IA +SEP + T+E+P
Sbjct: 363 TEATITGLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELP 402
Score = 43.6 bits (98), Expect = 0.004
Identities = 66/277 (23%), Positives = 100/277 (36%), Gaps = 37/277 (13%)
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
T +++ LQP Y + + A+N G+S+P VT + DV V++ +
Sbjct: 2 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-----IK 56
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLS 247
+ WE PQ G + Y V + L + P G T L
Sbjct: 57 IAWESPQ-----GQVSRYRVTYSSPEDGIHELFPA-PDGEEDTAE-------------LQ 97
Query: 248 GLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPP 307
GL+ + Y V V A + +P+ P L+ ++ S+ W PP
Sbjct: 98 GLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPA--PTDLKFTQVTPTSLSAQWTPP 152
Query: 308 PMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAG 367
N L GYRV P + G + +SGL T Y V+V A
Sbjct: 153 -----NVQLTGYRVRVTP-KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 206
Query: 368 DGVRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
R A T E+V S P + ++ I +SW
Sbjct: 207 TS-RPAQGVVTTLENV-SPPRRARVTDATETTITISW 241
>U42458-1|AAD09450.1| 287|Homo sapiens fibronectin protein.
Length = 287
Score = 63.3 bits (147), Expect = 5e-09
Identities = 71/293 (24%), Positives = 115/293 (39%), Gaps = 38/293 (12%)
Query: 71 EMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSA 130
++P+++ V+ ++ ISW P + Y + Y E + P Q+ VPGS ++A
Sbjct: 1 DVPRDLEVVAATPTSLLISWDAPAV---TVRYYRITYGETGGNSPV--QEFTVPGSKSTA 55
Query: 131 SVQNLQPATSYHLRIIAENRLGQS-EPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
++ L+P Y + + A G S S+P+ + E+ P ++V + V
Sbjct: 56 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVK 113
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P + + GY V T +GPG + AG ++ T+ GL
Sbjct: 114 WLPS-----SSPVTGYRV---------TTTPKNGPGPTK-----TKTAGPDQTEMTIEGL 154
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
Q Y V V A N + +P+ P L+ ++ S+ W PP
Sbjct: 155 QPTVEYVVSVYAQNP---SGESQPLVQTAVTTIPA--PTDLKFTQVTPTSLSAQWTPP-- 207
Query: 310 RGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
N L GYRV P + G + +SGL T Y V+V A
Sbjct: 208 ---NVQLTGYRVRVTP-KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 256
Score = 52.0 bits (119), Expect = 1e-05
Identities = 61/246 (24%), Positives = 98/246 (39%), Gaps = 24/246 (9%)
Query: 287 PGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTT 346
P L+ A + S+ +SW+ P + R YR+TY GN + G +T
Sbjct: 3 PRDLEVVAATPTSLLISWDAPAVTVRY-----YRITYGETG---GNSPVQEFTVPGSKST 54
Query: 347 --LSGLRRYTNYSVTVCAFTAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVS 403
+SGL+ +Y++TV A T GD + P+ + ++ P+ ++ N I V
Sbjct: 55 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI-DKPSQMQVTDVQDNSISVK 113
Query: 404 WLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSAST 463
WLP SSP + GY ++ T + P P + V A
Sbjct: 114 WLPSSSP---VTGYR--VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 168
Query: 464 RLGEGE---ATRVVTV-LPSDSVPARITSFSRNIVTPW-KENISLSCNKVGVPAPATTWT 518
GE + T V T+ P+D ++T S + W N+ L+ +V V T
Sbjct: 169 PSGESQPLVQTAVTTIPAPTDLKFTQVTPTS--LSAQWTPPNVQLTGYRVRVTPKEKTGP 226
Query: 519 MNGVGL 524
M + L
Sbjct: 227 MKEINL 232
Score = 32.7 bits (71), Expect = 7.5
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P +++ ++ WT P N + Y V+ ++ P + P S +S V
Sbjct: 187 PTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVTPKEKTGPMKEIN-LAPDS-SSVVV 241
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRV 178
L AT Y + + A S P+Q V VTT E V PP+ RV
Sbjct: 242 SGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARV 284
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 63.3 bits (147), Expect = 5e-09
Identities = 66/283 (23%), Positives = 121/283 (42%), Gaps = 19/283 (6%)
Query: 490 SRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGT-----LTISMT 543
++ I W+ N I++SC+ P + W + + L + N+ + T L I+ T
Sbjct: 406 NQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPT 465
Query: 544 QSADSGNYTCSVENIHGRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQWSD-QGDGGS 601
D G Y C+ N G Y + + VP P + +++ + + ++ GG
Sbjct: 466 SDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGV 525
Query: 602 PILGYVINYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVH 660
PI Y ++ K + W+ ++ + VL NL T Y++ + A N G G D
Sbjct: 526 PIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQG---DYSK 582
Query: 661 AYTKGTVPVKPKHSQMI---TLNTTTVTVWLDSWGDGGCGILYFVIEYREM-SQPQWRLV 716
T+PV+ I + + + + DGG IL ++++YR + QW +
Sbjct: 583 IEIFQTLPVREPSPPSIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKEDQW--L 640
Query: 717 SNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA-LALYNFT 758
VQ + + L Y+++ITA N G++ +Y F+
Sbjct: 641 EKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFS 683
Score = 51.2 bits (117), Expect = 2e-05
Identities = 44/146 (30%), Positives = 73/146 (50%), Gaps = 13/146 (8%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGS 126
VP P +++I+ T ++S+ +P + G PI +Y V KE A E W + V G
Sbjct: 495 VPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIW----KIVRSHGV 550
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV--PSGPPQDVRVEAKSST 184
T + NL+P T+Y +R+ A N GQ + S+ +++ T V PS P + + S
Sbjct: 551 QTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSK-IEIFQTLPVREPSPPSIHGQPSSGKSF 609
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQ 210
+L +T ++D IL Y V ++
Sbjct: 610 KLSIT----KQDDGGAPILEYIVKYR 631
Score = 49.6 bits (113), Expect = 6e-05
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 5/103 (4%)
Query: 473 VVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTLRKNV 532
+V V P+ S+P + S N E ++ SC G P PA +W NG +E + +
Sbjct: 204 IVNVPPAISMPQK----SFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYIL 259
Query: 533 SSDGT-LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
T LT+ ++D G Y C N G DE ++V V P
Sbjct: 260 KGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQP 302
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASV 132
P +I ++ ++S T+ G +PI+ YIV+Y+ + +KV G+ +
Sbjct: 596 PPSIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKEDQWLEKKV--QGNKDHIIL 653
Query: 133 QNLQPATSYHLRIIAENRLGQSEPS 157
++LQ Y ++I A NRLG SEP+
Sbjct: 654 EHLQWTMGYEVQITAANRLGYSEPT 678
>AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens cDNA
FLJ43332 fis, clone NT2RI3006340, highly similar to
Myomesin 1. ).
Length = 1685
Score = 63.3 bits (147), Expect = 5e-09
Identities = 53/194 (27%), Positives = 85/194 (43%), Gaps = 17/194 (8%)
Query: 571 KVPPQPPI-LAVVDSYADSLHLQWSDQGD-GGSPILGYVINYKR----EHGDWEELQVEA 624
+ PP PP + ++S+ DS+ L W GG+ I GY +NY+ G W E V+A
Sbjct: 931 RAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKA 990
Query: 625 GTSE-HVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAY--TKGTVPVK-PKHSQMIT-- 678
+ E + + N YQ + A N G G P + + + T+ V P HS +
Sbjct: 991 VSEEAYKISNSKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEV 1050
Query: 679 LNTTTVTVWLDSWGDGGCGILYFVIEYRE--MSQPQWRLVSNSVQATERVF-SVSGLTPA 735
+ V W G + + ++ +E + QWR ++ + A + V+ V GL
Sbjct: 1051 RKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEA--AIKNVYLKVRGLKEG 1108
Query: 736 AHYQLRITAHNNAG 749
Y R+ A N AG
Sbjct: 1109 VSYVFRVRAINQAG 1122
Score = 61.3 bits (142), Expect = 2e-08
Identities = 88/413 (21%), Positives = 157/413 (38%), Gaps = 32/413 (7%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSV 127
VP P ++ V + + +SW P G+ I+ ++ + + E+W ++ P
Sbjct: 637 VPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTEL--PVKS 694
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTE---EVPSGPPQDVRVEAKSST 184
++ +L SY R+ N G EPS+ +VT ++P P + + + T
Sbjct: 695 PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGK-IIPSRNTDT 753
Query: 185 ELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT 244
++V+WE +D ++GYY+ S + P V+G SR
Sbjct: 754 SVVVSWE-ESKDA--KELVGYYIEASVAGSGKWEPCNNNP---------VKG-----SRF 796
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
T GL +Y V+A N+ ++ C ALS + ++
Sbjct: 797 TCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLT- 855
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGL-HTTLSGLRRYTNYSVTVCAF 363
RGR + N+ ++ L T +S + +T
Sbjct: 856 ---ASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQ 912
Query: 364 TAAGDG-VRAAPVYCHTEEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGV-LVGYTL-Y 420
AA G ++ P+ T+ PS P DI S R+ +++ W P G + GY + Y
Sbjct: 913 KAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNY 972
Query: 421 MSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRV 473
VI+ + + + S +++ S S +QF V+A G G + V
Sbjct: 973 REVIDGVPGKWREANVKAVSEEAYKISNSKENMVYQFQVAAMNMAGLGAPSAV 1025
Score = 58.0 bits (134), Expect = 2e-07
Identities = 143/643 (22%), Positives = 218/643 (33%), Gaps = 57/643 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P P +++ ++ I ISW QP G SPI+ Y + E +SW P
Sbjct: 510 PAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCND---TPVKF 566
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELI 187
V L SY R+ A N++G PS+ + + R A + ++I
Sbjct: 567 ARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQII 626
Query: 188 VTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPG-----GASYTVRTVEGAGTAR- 241
VT E P + G V E + VL PG G Y V E AGT
Sbjct: 627 VTEEEPSEGIVPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCE-AGTENW 683
Query: 242 -----------SRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLP--PG 288
R L L + +Y V+ NS + D +P PG
Sbjct: 684 QRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPG 743
Query: 289 ALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS 348
+ + + SV VSWE L GY + A V E + G T
Sbjct: 744 KIIPSRNTDTSVVVSWEESKDAKE---LVGYYIE-ASVAGSGKWEPCNNNPVKGSRFTCH 799
Query: 349 GLRRYTNYSVTVCAFTAAG--------DGVRA-APVYCHTEEDVPSAPADIKAAVSSRNK 399
GL +Y V A AAG + + A + DV A +D +++
Sbjct: 800 GLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRG 859
Query: 400 ILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWV 459
+ PP+ L+G + + + S E PP+
Sbjct: 860 RVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGK 919
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM 519
S S L + + R P D + SF ++V WK+ ++ +
Sbjct: 920 SKSDPL-KKKTDRAPPSPPCDI--TCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVI 976
Query: 520 NGV-GLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVE--------V 570
+GV G S+ IS ++ + + N+ G + E +
Sbjct: 977 DGVPGKWREANVKAVSEEAYKISNSKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTI 1036
Query: 571 KVPPQPPILAVVDSYADSLHLQWSDQ-GDGGSPILGYVINYKR---EHGDWEELQVEAGT 626
VP P L + DSL LQW G +P+ GY ++ K + W L A
Sbjct: 1037 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIK 1096
Query: 627 SEHV-LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
+ ++ + L G Y + A N+ G G P D+ T P
Sbjct: 1097 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRP 1139
Score = 58.0 bits (134), Expect = 2e-07
Identities = 63/290 (21%), Positives = 115/290 (39%), Gaps = 17/290 (5%)
Query: 283 PSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNE--DAVTKQI 340
P PP + C S+ + W+ P G + GY V Y V D + +A K +
Sbjct: 933 PPSPPCDITCLESFRDSMVLGWKQPDKTG-GAEITGYYVNYREVIDGVPGKWREANVKAV 991
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED----VPSAPADIKAAVSS 396
S +S + Y V A AG G +A C E+ VP P +K +
Sbjct: 992 SEEAYKISNSKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVR 1051
Query: 397 RNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSH---ETSRSPPRA 453
++ +++ W PP V T Y +++ + + R L+ + + + +
Sbjct: 1052 KDSLVLQWKPPVHSGRTPV--TGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGV 1109
Query: 454 THQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAP 513
++ F V A + G G+ + + + +++ P N+ +++ C+K+ P
Sbjct: 1110 SYVFRVRAINQAGVGKPSDLAGPVVAETRPG-TKEVVVNVDDDGVISLNFECDKM-TPKS 1167
Query: 514 ATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHG 560
+W+ + V E + R V S G +T D G Y+C V + G
Sbjct: 1168 EFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 1217
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 484 ARITSFSRNIVTPWK-ENISLSCNKVGVPAPATTWTMNGVGLES----TLRKNVSSDGTL 538
AR+ ++VT + + ++L+CN G P P +W N L S L+
Sbjct: 1572 ARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDGHCNLKFEAGRTAYF 1631
Query: 539 TISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDS 584
TI+ +ADSG Y V+N +G + +TV V +P + +A ++S
Sbjct: 1632 TINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALES 1677
Score = 46.4 bits (105), Expect = 6e-04
Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 499 ENISLSCNKVGVPA-----PATTWTMNGVGLESTLRKNVSSDG---TLTISMTQSADSGN 550
E +SL C V P P W NGV L + G TLT S D G
Sbjct: 420 ETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGL 479
Query: 551 YTCSVENIHGRDEVTYTV-------EVKVPPQPPI-LAVVDSYADSLHLQWSDQG-DGGS 601
YT V ++ + V E++ P P+ + +++ D + + W DGGS
Sbjct: 480 YTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGS 539
Query: 602 PILGYVINYKREHG--DWEEL-QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLP 655
PILGY I+ K E G W + + + L G Y + A N++G G P
Sbjct: 540 PILGYFID-KCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFP 595
Score = 39.5 bits (88), Expect = 0.065
Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAP---ESWPSTPQKVIVP 124
VP P +++ + + ++ + W P ++G +P+ Y V KEA + W + I
Sbjct: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI-- 1095
Query: 125 GSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVE 179
V+ L+ SY R+ A N+ G +PS E P V V+
Sbjct: 1096 -KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVD 1149
Score = 35.9 bits (79), Expect = 0.80
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 495 TPW-KENISLSCNKVGVPAPATTWTMNGV--GLESTLRKNV--SSDG--TLTISMTQSAD 547
T W KEN+ L C+ G P P TW N V + + K + S G TL I+ D
Sbjct: 287 TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINACDFED 346
Query: 548 SGNYTCSVENIHGRDEVTYTVEVK 571
+ Y S N+ G +V VK
Sbjct: 347 TAQYRASAMNVKGELSAYASVVVK 370
Score = 32.7 bits (71), Expect = 7.5
Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSPNG-VLVGY 417
E P+AP D+K ++++ I++SW P+ G ++GY
Sbjct: 507 EGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGY 544
Score = 32.3 bits (70), Expect = 9.9
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 663 TKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQ 721
++G VP P + + V + W G GI+YFV E E W+ V+ +
Sbjct: 633 SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFV-EKCEAGTENWQRVNTELP 691
Query: 722 ATERVFSVSGLTPAAHYQLRITAHNNAG 749
F++ L Y R+ N+AG
Sbjct: 692 VKSPRFALFDLAEGKSYCFRVRCSNSAG 719
>AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens
cDNA FLJ37794 fis, clone BRHIP3000488. ).
Length = 903
Score = 63.3 bits (147), Expect = 5e-09
Identities = 65/258 (25%), Positives = 109/258 (42%), Gaps = 26/258 (10%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TW +G+ + R ++ LTIS DSG ++N HG T
Sbjct: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
Query: 566 YTVEVKVPP----QPPILAVVDSYADSLHLQWS-DQGDGGSPILGYVINYKREHGD-WEE 619
+ V PP QP V D +++ + W+ DGG+P+LGY++ +++ + W
Sbjct: 693 LHLSVLEPPGFASQPQ---VTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVP 749
Query: 620 LQVE--AGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKH---- 673
+ + GT + + L T Y+ + A N+ G G P + + PVKP
Sbjct: 750 VNKDPIQGT-KCTVDGLLEDTEYEFRVIAVNKAGPGQP-SVPSSSVVAKDPVKPPGLVQD 807
Query: 674 -SQMITLNTTTVTVWLD-SWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSG 731
+ N++ W + + GD G +++E +W + + + ++V G
Sbjct: 808 LHVSDSSNSSISLAWREPAEGDPPSG---YILEMWAEDTKEWSKCT-KIPISGTCYTVGG 863
Query: 732 LTPAAHYQLRITAHNNAG 749
L Y RI A N AG
Sbjct: 864 LIERQKYFFRIRAVNEAG 881
Score = 59.3 bits (137), Expect = 8e-08
Identities = 43/158 (27%), Positives = 70/158 (44%), Gaps = 6/158 (3%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEAPESWPSTPQKVIVPGSVT 128
P +V D + I+W P G +P++ YIV+ ++ + K + G T
Sbjct: 701 PGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG--T 758
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE--VPSGPPQDVRVEAKSSTEL 186
+V L T Y R+IA N+ G +PS P ++ P G QD+ V S++ +
Sbjct: 759 KCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSSI 818
Query: 187 IVTW-EPPQRDLWNGNILGYYVGFQELNSNSTVLIASG 223
+ W EP + D +G IL + + S T + SG
Sbjct: 819 SLAWREPAEGDPPSGYILEMWAEDTKEWSKCTKIPISG 856
Score = 37.9 bits (84), Expect = 0.20
Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 16/153 (10%)
Query: 286 PPGAL---QCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTD--WYG-NEDAVTKQ 339
PPG Q ++ ++V ++W P G +L GY V W N+D
Sbjct: 700 PPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVL-GYIVERRKKGSNLWVPVNKDP---- 754
Query: 340 ISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPA---DIKAAVSS 396
I G T+ GL T Y V A AG G + P +D P D+ + SS
Sbjct: 755 IQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSS 814
Query: 397 RNKILVSWLPPSSPNGVLVGYTLYMSVIEDGRE 429
+ I ++W P+ + GY L M ED +E
Sbjct: 815 NSSISLAWREPAEGDPP-SGYILEMWA-EDTKE 845
>BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein.
Length = 867
Score = 62.5 bits (145), Expect = 8e-09
Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 13/217 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVS---SDGTLTISMTQSADSGNYTCSVENIHGRDEVT 565
G P P TW +G+ + R ++ LTIS DSG ++N HG T
Sbjct: 633 GKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATAT 692
Query: 566 YTVEVKVPPQPP--ILAVVDSYADSLHLQW-SDQGDGGSPILGYVINYKREHG--DWEEL 620
+ V P+PP + ++ +H++W + + +GG P+ +++ +R G W ++
Sbjct: 693 LHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVE-RRAVGKKSWIKI 751
Query: 621 -QVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTV--PVKPKHSQMI 677
+V+ + + G YQ I A N G P + + + P Q+
Sbjct: 752 GEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVT 811
Query: 678 TLNTTTVTV-WLDSWGDGGCGILYFVIEYREMSQPQW 713
+ VT+ W DGG +L +++E R+ W
Sbjct: 812 DVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW 848
Score = 54.8 bits (126), Expect = 2e-06
Identities = 41/171 (23%), Positives = 72/171 (42%), Gaps = 8/171 (4%)
Query: 57 TVDLRIGSLSHQVPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKEA-PESW 114
T L + L P + + ++ + + W P G P+ +IV+ + +SW
Sbjct: 690 TATLHLSVLDRPKPPQGR-VEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSW 748
Query: 115 PSTPQKVIVPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEV-PSGPP 173
+ V G VT+ S ++ +Y RI+A N G S+P + +V + P G
Sbjct: 749 IKIGE---VDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFA 805
Query: 174 QDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGP 224
+V + + +TW P +D +LGY V ++ SN V + P
Sbjct: 806 SQPQVTDVTKEAVTITWNAPTQD-GGAPVLGYIVERRKKGSNLWVPVNKDP 855
Score = 33.5 bits (73), Expect = 4.3
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 7/106 (6%)
Query: 471 TRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM-NGVGLESTLR 529
TR + DSVP + + + P + G P P +W +G+ ++ + +
Sbjct: 55 TRSSNIPAGDSVPEFVEK-PQPVTAPEGDKAVFRARVQGNPKPHISWKRESGIPIKESAK 113
Query: 530 ---KNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKV 572
+++ + L + S DS NY C N H + YTV + V
Sbjct: 114 IFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHA--DAIYTVSLLV 157
>AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein
protein.
Length = 584
Score = 62.5 bits (145), Expect = 8e-09
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM- 519
A ++G+ E V V+ + + T + + P+ + ++++C G P P TW
Sbjct: 82 AENQVGKDEMRVRVKVVTAPATIRNKTCLA--VQVPYGDVVTVACEAKGEPMPKVTWLSP 139
Query: 520 -NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N V S+ + + DGTL I Q +DSGNYTC V N G D T + V V P
Sbjct: 140 TNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQP 195
Score = 53.6 bits (123), Expect = 4e-06
Identities = 36/114 (31%), Positives = 49/114 (42%), Gaps = 4/114 (3%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM-NGVGL 524
GE +TVL P S I ISL+C+ G P P+ W + NG L
Sbjct: 281 GEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDL 340
Query: 525 ES---TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
+S R +DG L IS S D+G Y C N G E +++V + P+
Sbjct: 341 QSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPE 394
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
Query: 483 PARITSFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNG-----VGLESTLRKN--VSS 534
P RITS ++ N + L+C +G+P TW + G+++ L N +
Sbjct: 488 PPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHP 547
Query: 535 DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
G+LTI D+G Y C +NI G D T + V
Sbjct: 548 QGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 583
Score = 39.1 bits (87), Expect = 0.086
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 499 ENISLSCNKVGVPAPATTWTM-NGVGLES--TL-RKNVSSDGTLTISMTQSADSGNYTCS 554
E + L C G +WT+ NG+ LE TL R ++ +GTLT+ D G Y C
Sbjct: 409 ETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 468
Query: 555 VENIHGRDEVTYTVEVKVPPQPP 577
+E +G VT ++ V V PP
Sbjct: 469 METEYG-PSVT-SIPVIVIAYPP 489
Score = 38.7 bits (86), Expect = 0.11
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLES-----------TLRKNVSSDGTLTISMTQSADS 548
++ + C G+P P +W++ L + T R V ++GTL + +
Sbjct: 16 DLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREE 75
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP----QPPILAVVDSYADSLHLQWSDQGD 598
G+YTC EN G+DE+ V+V P LAV Y D + + +G+
Sbjct: 76 GDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTCLAVQVPYGDVVTVACEAKGE 129
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 503 LSCNKVGVPAPATTWTM-NGVGLESTLRKN---VSSDGTLTISMTQSADSGNYTCSVENI 558
+ C G+P P W GV L + N V +G+L I + +DS C N
Sbjct: 220 IDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNE 279
Query: 559 HGRDEVTYTVEVKVPPQPPI 578
G + + V P + PI
Sbjct: 280 GGEARLILQLTVLEPMEKPI 299
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 62.1 bits (144), Expect = 1e-08
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 461 ASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM- 519
A ++G+ E V V+ + + T + + P+ + ++++C G P P TW
Sbjct: 2326 AENQVGKDEMRVRVKVVTAPATIRNKTYLA--VQVPYGDVVTVACEAKGEPMPKVTWLSP 2383
Query: 520 -NGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
N V S+ + + DGTL I Q +DSGNYTC V N G D T + V V P
Sbjct: 2384 TNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQP 2439
Score = 53.6 bits (123), Expect = 4e-06
Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 6/114 (5%)
Query: 468 GEATRVV--TVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM-NGVGL 524
GEA +V TVL P S I ISL+C+ G P P+ W + NG L
Sbjct: 2525 GEARLIVQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDL 2584
Query: 525 ES---TLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQ 575
+S R +DG L IS S D+G Y C N G E +++V + P+
Sbjct: 2585 QSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPE 2638
Score = 53.2 bits (122), Expect = 5e-06
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 6/103 (5%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLEST-----LRKNVSSDGT 537
P +T + + + + C G P P TWT G T R V +GT
Sbjct: 1853 PQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGT 1912
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILA 580
L I Q D G Y C+ N+HG D + + V V QP ILA
Sbjct: 1913 LVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTV-QQPQILA 1954
Score = 42.7 bits (96), Expect = 0.007
Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 468 GEATRVVTV-LPSDSVPARITSFS-RNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G A R V + + + ARIT S R + + L C+ G P P W + +
Sbjct: 2129 GSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMI 2188
Query: 526 STL-----RKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPP 574
L R V ++GTL + D+G+Y C N G D V V+V + P
Sbjct: 2189 DALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKP 2242
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
Query: 483 PARITSFSRNIVTPWKEN-ISLSCNKVGVPAPATTWTMNG-----VGLESTLRKN--VSS 534
P RITS ++ N + L+C +G+P TW + G+++ L N +
Sbjct: 2732 PPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHP 2791
Query: 535 DGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEV 570
G+LTI D+G Y C +NI G D T + V
Sbjct: 2792 QGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
Score = 41.5 bits (93), Expect = 0.016
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGV----GLESTLRKNVSSDGTLTISMTQSADSGNYTCS 554
E+++L CN + +P +W + L +T + +GTL+I Q +DSG Y C
Sbjct: 593 ESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCV 652
Query: 555 VENIHGRDEVTYTVEV 570
N G D T + V
Sbjct: 653 AVNQQGADHFTVGITV 668
Score = 39.1 bits (87), Expect = 0.086
Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 499 ENISLSCNKVGVPAPATTWTM-NGVGLES--TL-RKNVSSDGTLTISMTQSADSGNYTCS 554
E + L C G +WT+ NG+ LE TL R ++ +GTLT+ D G Y C
Sbjct: 2653 ETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 2712
Query: 555 VENIHGRDEVTYTVEVKVPPQPP 577
+E +G VT ++ V V PP
Sbjct: 2713 METEYG-PSVT-SIPVIVIAYPP 2733
Score = 38.7 bits (86), Expect = 0.11
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 500 NISLSCNKVGVPAPATTWTMNGVGLES-----------TLRKNVSSDGTLTISMTQSADS 548
++ + C G+P P +W++ L + T R V ++GTL + +
Sbjct: 2260 DLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREE 2319
Query: 549 GNYTCSVENIHGRDEVTYTVEVKVPP----QPPILAVVDSYADSLHLQWSDQGD 598
G+YTC EN G+DE+ V+V P LAV Y D + + +G+
Sbjct: 2320 GDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGE 2373
Score = 37.5 bits (83), Expect = 0.26
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 7/102 (6%)
Query: 483 PARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLESTL-----RKNVSSDGT 537
P + S +++ + I++ C G PAP +W + T+ R + + T
Sbjct: 1950 PQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRT 2009
Query: 538 LTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPIL 579
L+I +D G Y C N G D + + + V PP++
Sbjct: 2010 LSIKEASFSDRGVYKCVASNAAGADSL--AIRLHVAALPPVI 2049
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 503 LSCNKVGVPAPATTWTM-NGVGLESTLRKN---VSSDGTLTISMTQSADSGNYTCSVENI 558
+ C G+P P W GV L + N V +G+L I + +DS C N
Sbjct: 2464 IDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNE 2523
Query: 559 HGRDEVTYTVEVKVPPQPPI 578
G + + V P + PI
Sbjct: 2524 GGEARLIVQLTVLEPMEKPI 2543
Score = 34.3 bits (75), Expect = 2.4
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 503 LSCNKVGVPAPATTWTM-NGVGLESTL-----RKNVSSDGTLTISMTQSADSGNYTCSVE 556
LSCN +P+ W + +G L++ + + ++ S G L I + +DSG Y C +
Sbjct: 499 LSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQ 558
Query: 557 NIHGRDEVTYTVEVKVPPQPP 577
D + Y V V+ P P
Sbjct: 559 VRDEMDRMVYRVLVQSPSTQP 579
Score = 33.9 bits (74), Expect = 3.2
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 492 NIVTPWKENISLSCNKVGVPAPATTWTM-NGVGLEST--LRKN--VSSDGTLTISMTQSA 546
NI P +I + C P P+ W + +G + + L N V +GTL I
Sbjct: 2056 NISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPK 2115
Query: 547 DSGNYTCSVENIHGRDEVTYTVEVK 571
DSG Y C N+ G T + V+
Sbjct: 2116 DSGRYECVAANLVGSARRTVQLNVQ 2140
>BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1264
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
VPE P + ++ ++W G SPI + V+YK S W + + P S
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDI--PPSK 777
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ---SEPSQPVQV----TTTEEVPSGPPQDVRVEA 180
S V++L+P ++Y R+IA N G+ S S+P QV P P EA
Sbjct: 778 LSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEA 837
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
S T++++ W N I G+Y+ ++ +S++ + Y VEG +
Sbjct: 838 VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDN---------DSDYKRDVVEG---S 885
Query: 241 RSRTTLSGLQKHAAYAVVVQAYN 263
+ + LQ +Y + +Q +N
Sbjct: 886 KQWHMIGHLQPETSYDIKMQCFN 908
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/85 (27%), Positives = 39/85 (45%)
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERV 726
VP P + T + T+V V +GG I F +EY+ M W + + + ++
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 727 FSVSGLTPAAHYQLRITAHNNAGHA 751
V L P + Y+ R+ A N+ G +
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYGES 804
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 570 VKVPPQPPILAVVDSYA-DSLHLQWSDQGDGGSPILGYVINYKREH------GDWEELQV 622
+ VP P IL+ ++ D+ +L W DGG PI Y + Y++ G W ++V
Sbjct: 574 ISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRV 633
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
+E L L + Y++ + A + G G P + +K
Sbjct: 634 PGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSK 675
Score = 40.3 bits (90), Expect = 0.037
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG 536
SD V + S+ + + ++L C GVPAP W +G + S R+ S
Sbjct: 217 SDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSH-- 274
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDE-VTYTVEV 570
L ADSGNY+C N G + VTY V V
Sbjct: 275 -LATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNV 308
Score = 40.3 bits (90), Expect = 0.037
Identities = 47/224 (20%), Positives = 83/224 (37%), Gaps = 17/224 (7%)
Query: 168 VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG--PG 225
VP P + + S T + VTW P R I + V ++ + +++ ++ A P
Sbjct: 720 VPEAPDRPT-ISTASETSVYVTWIP--RANGGSPITAFKVEYKRMRTSNWLVAAEDIPPS 776
Query: 226 GASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL 285
S VR++E T + R H +++ S P
Sbjct: 777 KLSVEVRSLEPGSTYKFRVIAIN---HYG-----ESFRSSASRPYQVVGFPNRFSSRPIT 828
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P A+S + + W P N +QG+ + Y P TD + D + G
Sbjct: 829 GPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRP-TDSDNDSDYKRDVVEGSKQ 887
Query: 346 --TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSA 386
+ L+ T+Y + + F G+ + + C T+ + VP A
Sbjct: 888 WHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGA 931
Score = 38.7 bits (86), Expect = 0.11
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 86 IQISWTQ-PYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
I + WT P + N+ PI + + Y+ S ++ +V GS + +LQP TSY +
Sbjct: 843 IMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDI 902
Query: 144 RIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDVR 177
++ N G+SE S + T + VP V+
Sbjct: 903 KMQCFNEGGESEFSNVMICETKVKRVPGASEYPVK 937
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPES--WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T + W G PI Y V+Y++ + + V VPGS + L+P++ Y
Sbjct: 593 TYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYE 652
Query: 143 LRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ ++A + G+ +P+ T+ E+ S
Sbjct: 653 VLMVARSAAGEGQPAMLTFRTSKEKTAS 680
Score = 33.9 bits (74), Expect = 3.2
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ +C+ G PAP TW N + + R + +G L IS D G Y C +N G
Sbjct: 329 VHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG-LKISGVTVEDVGMYQCVADNGIG 387
Query: 561 RDEVTYTVEVK 571
T +E++
Sbjct: 388 FMHSTGRLEIE 398
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
VP P + + S+++ W + +GGSPI + + YKR +W + S+
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 631 LP--NLWCGTRYQLYITAFNRIG 651
+ +L G+ Y+ + A N G
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYG 802
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
VPE P + ++ ++W G SPI + V+YK S W + + P S
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDI--PPSK 777
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ---SEPSQPVQV----TTTEEVPSGPPQDVRVEA 180
S V++L+P ++Y R+IA N G+ S S+P QV P P EA
Sbjct: 778 LSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEA 837
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
S T++++ W N I G+Y+ ++ +S++ + Y VEG +
Sbjct: 838 VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDN---------DSDYKRDVVEG---S 885
Query: 241 RSRTTLSGLQKHAAYAVVVQAYN 263
+ + LQ +Y + +Q +N
Sbjct: 886 KQWHMIGHLQPETSYDIKMQCFN 908
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/85 (27%), Positives = 39/85 (45%)
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERV 726
VP P + T + T+V V +GG I F +EY+ M W + + + ++
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 727 FSVSGLTPAAHYQLRITAHNNAGHA 751
V L P + Y+ R+ A N+ G +
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYGES 804
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG 536
SD V + S+ + + ++L C GVPAP W +G + ES R+ S
Sbjct: 217 SDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLYSH-- 274
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDE-VTYTVEV 570
L ADSGNY+C N G + VTY V V
Sbjct: 275 -LATDSVDPADSGNYSCMAGNKSGDVKYVTYMVNV 308
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 570 VKVPPQPPILAVVDSYA-DSLHLQWSDQGDGGSPILGYVINYKREH------GDWEELQV 622
+ VP P IL+ ++ D+ +L W DGG PI Y + Y++ G W ++V
Sbjct: 574 ISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRV 633
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
+E L L + Y++ + A + G G P + +K
Sbjct: 634 PGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSK 675
Score = 40.3 bits (90), Expect = 0.037
Identities = 47/224 (20%), Positives = 83/224 (37%), Gaps = 17/224 (7%)
Query: 168 VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG--PG 225
VP P + + S T + VTW P R I + V ++ + +++ ++ A P
Sbjct: 720 VPEAPDRPT-ISTASETSVYVTWIP--RANGGSPITAFKVEYKRMRTSNWLVAAEDIPPS 776
Query: 226 GASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL 285
S VR++E T + R H +++ S P
Sbjct: 777 KLSVEVRSLEPGSTYKFRVIAIN---HYG-----ESFRSSASRPYQVVGFPNRFSSRPIT 828
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P A+S + + W P N +QG+ + Y P TD + D + G
Sbjct: 829 GPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRP-TDSDNDSDYKRDVVEGSKQ 887
Query: 346 --TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSA 386
+ L+ T+Y + + F G+ + + C T+ + VP A
Sbjct: 888 WHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGA 931
Score = 38.7 bits (86), Expect = 0.11
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 86 IQISWTQ-PYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
I + WT P + N+ PI + + Y+ S ++ +V GS + +LQP TSY +
Sbjct: 843 IMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDI 902
Query: 144 RIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDVR 177
++ N G+SE S + T + VP V+
Sbjct: 903 KMQCFNEGGESEFSNVMICETKVKRVPGASEYPVK 937
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPES--WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T + W G PI Y V+Y++ + + V VPGS + L+P++ Y
Sbjct: 593 TYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYE 652
Query: 143 LRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ ++A + G+ +P+ T+ E+ S
Sbjct: 653 VLMVARSAAGEGQPAMLTFRTSKEKTAS 680
Score = 33.9 bits (74), Expect = 3.2
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 501 ISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHG 560
+ +C+ G PAP TW N + + R + +G L IS D G Y C +N G
Sbjct: 329 VHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG-LKISGVTVEDVGMYQCVADNGIG 387
Query: 561 RDEVTYTVEVK 571
T +E++
Sbjct: 388 FMHSTGRLEIE 398
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
VP P + + S+++ W + +GGSPI + + YKR +W + S+
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 631 LP--NLWCGTRYQLYITAFNRIG 651
+ +L G+ Y+ + A N G
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYG 802
>BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1163
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 19/217 (8%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G TRV+ P PA I + + C+ G P P +WT G GL+
Sbjct: 389 GPSPVTRVLLKAP----PAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ 444
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSY 585
+ V S+ +L + G++ CS N R + V V + P ++ V
Sbjct: 445 G--QAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYV-LGTSPHVVTNVSVV 501
Query: 586 A--DSLHLQWSDQGDGGSPILGYVINYK-------REHGDWEELQVEAGTSEHVLPNLWC 636
A ++ W DGG + + + Y R H DW L V G + ++P L
Sbjct: 502 ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQP 560
Query: 637 GTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKP 671
T+YQ + A N++G+G +IV + +G T P P
Sbjct: 561 HTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAP 597
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E ++L C G P P TW + G L + +GTL I + SG YTC +
Sbjct: 152 EPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASST 211
Query: 559 HGRDEVTYTVEVKVPPQPPILAV 581
G T+ ++ V PP++ V
Sbjct: 212 EG--SATHATQLLV-LGPPVIVV 231
Score = 36.7 bits (81), Expect = 0.46
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-TWTMNGVGLE 525
EG AT +L P I +N +++SL+C+ PA T +W + + +
Sbjct: 212 EGSATHATQLLVLG--PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVF 269
Query: 526 --STLRKNVSS--DGTLTISMTQSADSGNYTCSVEN--IHGRDEVTYTVEVKVPPQPPIL 579
S L+ V DG+L + TQ D+G YTC N +H Y + +P I
Sbjct: 270 HISRLQPRVQILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLCMP--GVIR 327
Query: 580 AVVDSYADSLHLQWSDQG 597
V + L + W+ G
Sbjct: 328 CPVRANPPLLFVSWTKDG 345
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 19/142 (13%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK---EAPESWPSTPQKVIVPGS 126
P + N+ V+ + +SW + G + + V Y + P+ + VP
Sbjct: 492 PHVVTNVSVV-ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVG 549
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-----PVQVTTTEEVPSGPPQDV----- 176
V LQP T Y ++A+N+LG S+ P + TT P PP ++
Sbjct: 550 AAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLS 609
Query: 177 ----RVEAKSSTELIVTWEPPQ 194
V ++ +++ W+PP+
Sbjct: 610 PPRGLVAVRTPRGVLLHWDPPE 631
>AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1179
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 19/217 (8%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G TRV+ P PA I + + C+ G P P +WT G GL+
Sbjct: 405 GPSPVTRVLLKAP----PAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ 460
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSY 585
+ V S+ +L + G++ CS N R + V V + P ++ V
Sbjct: 461 G--QAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYV-LGTSPHVVTNVSVV 517
Query: 586 A--DSLHLQWSDQGDGGSPILGYVINYK-------REHGDWEELQVEAGTSEHVLPNLWC 636
A ++ W DGG + + + Y R H DW L V G + ++P L
Sbjct: 518 ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQP 576
Query: 637 GTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKP 671
T+YQ + A N++G+G +IV + +G T P P
Sbjct: 577 HTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAP 613
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E ++L C G P P TW + G L + +GTL I + SG YTC +
Sbjct: 152 EPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASST 211
Query: 559 HGRDEVTYTVEVKVPPQPPILAV 581
G T+ ++ V PP++ V
Sbjct: 212 EG--SATHATQLLV-LGPPVIVV 231
Score = 36.7 bits (81), Expect = 0.46
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-TWTMNGVGLE 525
EG AT +L P I +N +++SL+C+ PA T +W + + +
Sbjct: 212 EGSATHATQLLVLG--PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVF 269
Query: 526 --STL--RKNVSSDGTLTISMTQSADSGNYTCSVEN--IHGRD-----EVTYTVEV-KVP 573
S L R + DG+L + TQ D+G YTC N +H V Y +V +P
Sbjct: 270 HISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMP 329
Query: 574 PQPPI 578
P+ P+
Sbjct: 330 PETPL 334
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 19/142 (13%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK---EAPESWPSTPQKVIVPGS 126
P + N+ V+ + +SW + G + + V Y + P+ + VP
Sbjct: 508 PHVVTNVSVV-ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVG 565
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-----PVQVTTTEEVPSGPPQDV----- 176
V LQP T Y ++A+N+LG S+ P + TT P PP ++
Sbjct: 566 AAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLS 625
Query: 177 ----RVEAKSSTELIVTWEPPQ 194
V ++ +++ W+PP+
Sbjct: 626 PPRGLVAVRTPRGVLLHWDPPE 647
>AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin
superfamily, member 9 protein.
Length = 1163
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 19/217 (8%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G TRV+ P PA I + + C+ G P P +WT G GL+
Sbjct: 389 GPSPVTRVLLKAP----PAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ 444
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSY 585
+ V S+ +L + G++ CS N R + V V + P ++ V
Sbjct: 445 G--QAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYV-LGTSPHVVTNVSVV 501
Query: 586 A--DSLHLQWSDQGDGGSPILGYVINYK-------REHGDWEELQVEAGTSEHVLPNLWC 636
A ++ W DGG + + + Y R H DW L V G + ++P L
Sbjct: 502 ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQP 560
Query: 637 GTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKP 671
T+YQ + A N++G+G +IV + +G T P P
Sbjct: 561 HTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAP 597
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E ++L C G P P TW + G L + +GTL I + SG YTC +
Sbjct: 152 EPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASST 211
Query: 559 HGRDEVTYTVEVKVPPQPPILAV 581
G T+ ++ V PP++ V
Sbjct: 212 EG--SATHATQLLV-LGPPVIVV 231
Score = 36.7 bits (81), Expect = 0.46
Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 11/138 (7%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-TWTMNGVGLE 525
EG AT +L P I +N +++SL+C+ PA T +W + + +
Sbjct: 212 EGSATHATQLLVLG--PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVF 269
Query: 526 --STL--RKNVSSDGTLTISMTQSADSGNYTCSVEN--IHGRDEVTYTVEVKVPPQPPIL 579
S L R + DG+L + TQ D+G YTC N +H Y + +P I
Sbjct: 270 HISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLCMP--GVIR 327
Query: 580 AVVDSYADSLHLQWSDQG 597
V + L + W+ G
Sbjct: 328 CPVRANPPLLFVSWTKDG 345
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 19/142 (13%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK---EAPESWPSTPQKVIVPGS 126
P + N+ V+ + +SW + G + + V Y + P+ + VP
Sbjct: 492 PHVVTNVSVV-ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVG 549
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-----PVQVTTTEEVPSGPPQDV----- 176
V LQP T Y ++A+N+LG S+ P + TT P PP ++
Sbjct: 550 AAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLS 609
Query: 177 ----RVEAKSSTELIVTWEPPQ 194
V ++ +++ W+PP+
Sbjct: 610 PPRGLVAVRTPRGVLLHWDPPE 631
>AK129856-1|BAC85243.1| 295|Homo sapiens protein ( Homo sapiens
cDNA FLJ26346 fis, clone HRT04038, highly similar to
Homo sapiens titin (TTN), transcript variant N2-B. ).
Length = 295
Score = 61.7 bits (143), Expect = 1e-08
Identities = 47/185 (25%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 573 PPQPPILAVVDSYA-DSLHLQWSD-QGDGGSPILGYVINYKREHGD-WEELQVEAGTS-E 628
PP PP V + DS+ + W DGGS I+ Y++ + + G W + + T
Sbjct: 25 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR 84
Query: 629 HVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK-GTV--PVKPKHSQMITLNTTTVT 685
+ + L G Y+ I A N G P Y TV P P + +++ + ++++
Sbjct: 85 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 144
Query: 686 V-WLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ W DGG I +++E + +W++V+ ++++GLT Y++RI A
Sbjct: 145 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 204
Query: 745 HNNAG 749
N+ G
Sbjct: 205 MNSEG 209
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/171 (29%), Positives = 69/171 (40%), Gaps = 9/171 (5%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGSV 127
P+ PKN V ++ + W P + G S IINYIV+ ++ A + W +K +
Sbjct: 26 PDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD--- 82
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQSEPS--QPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
V L Y RI+AEN G S PS P GPP + RV S +
Sbjct: 83 LRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSS 142
Query: 186 LIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEG 236
+ + W P D I GY V L I + P G T T+ G
Sbjct: 143 ISIAWNKPIYD-GGSEITGYMVEI-ALPEEDEWQIVTPPAGLKATSYTITG 191
Score = 44.4 bits (100), Expect = 0.002
Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 12/124 (9%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQP-YAGNSPIINYIVQYKEAPE-SWPSTPQKVIVPGSV 127
P P N RV+D +I I+W +P Y G S I Y+V+ E W Q V P +
Sbjct: 127 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEW----QIVTPPAGL 182
Query: 128 --TSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE 185
TS ++ L Y +RI A N G EP+ V T E PP+ +E +
Sbjct: 183 KATSYTITGLTENQEYKIRIYAMNSEGLGEPAL-VPGTPKAEDRMLPPE---IELDADLR 238
Query: 186 LIVT 189
+VT
Sbjct: 239 KVVT 242
>AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.
Length = 1264
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
VPE P + ++ ++W G SPI + V+YK S W + + P S
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDI--PPSK 777
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ---SEPSQPVQV----TTTEEVPSGPPQDVRVEA 180
S V++L+P ++Y R+IA N G+ S S+P QV P P EA
Sbjct: 778 LSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEA 837
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
S T++++ W N I G+Y+ ++ +S++ + Y VEG +
Sbjct: 838 VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDN---------DSDYKRDVVEG---S 885
Query: 241 RSRTTLSGLQKHAAYAVVVQAYN 263
+ + LQ +Y + +Q +N
Sbjct: 886 KQWHMIGHLQPETSYDIKMQCFN 908
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/85 (27%), Positives = 39/85 (45%)
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERV 726
VP P + T + T+V V +GG I F +EY+ M W + + + ++
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 727 FSVSGLTPAAHYQLRITAHNNAGHA 751
V L P + Y+ R+ A N+ G +
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYGES 804
Score = 41.9 bits (94), Expect = 0.012
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNG--VGLESTLRKNVSSDG 536
SD V + S+ + + ++L C GVPAP W +G + S R+ S
Sbjct: 217 SDDVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLYSH-- 274
Query: 537 TLTISMTQSADSGNYTCSVENIHGRDE-VTYTVEV 570
L ADSGNY+C N G E VTY V V
Sbjct: 275 -LATDSVDPADSGNYSCMAGNKSGDVEYVTYMVNV 308
Score = 41.9 bits (94), Expect = 0.012
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 570 VKVPPQPPILAVVDSYA-DSLHLQWSDQGDGGSPILGYVINYKREH------GDWEELQV 622
+ VP P IL+ ++ D+ +L W DGG PI Y + Y++ G W ++V
Sbjct: 574 ISVPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRV 633
Query: 623 EAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTK 664
+E L L + Y++ + A + G G P I +K
Sbjct: 634 PGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMITFRTSK 675
Score = 40.3 bits (90), Expect = 0.037
Identities = 47/224 (20%), Positives = 83/224 (37%), Gaps = 17/224 (7%)
Query: 168 VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG--PG 225
VP P + + S T + VTW P R I + V ++ + +++ ++ A P
Sbjct: 720 VPEAPDRPT-ISTASETSVYVTWIP--RANGGSPITAFKVEYKRMRTSNWLVAAEDIPPS 776
Query: 226 GASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL 285
S VR++E T + R H +++ S P
Sbjct: 777 KLSVEVRSLEPGSTYKFRVIAIN---HYG-----ESFRSSASRPYQVVGFPNRFSSRPIT 828
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P A+S + + W P N +QG+ + Y P TD + D + G
Sbjct: 829 GPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRP-TDSDNDSDYKRDVVEGSKQ 887
Query: 346 --TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSA 386
+ L+ T+Y + + F G+ + + C T+ + VP A
Sbjct: 888 WHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGA 931
Score = 38.7 bits (86), Expect = 0.11
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 86 IQISWTQ-PYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
I + WT P + N+ PI + + Y+ S ++ +V GS + +LQP TSY +
Sbjct: 843 IMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDI 902
Query: 144 RIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDVR 177
++ N G+SE S + T + VP V+
Sbjct: 903 KMQCFNEGGESEFSNVMICETKVKRVPGASEYPVK 937
Score = 38.3 bits (85), Expect = 0.15
Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 85 TIQISWTQPYAGNSPIINYIVQYKEAPES--WPSTPQKVIVPGSVTSASVQNLQPATSYH 142
T + W G PI Y V+Y++ + + V VPGS + L+P++ Y
Sbjct: 593 TYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPGSENELHLAELEPSSLYE 652
Query: 143 LRIIAENRLGQSEPSQPVQVTTTEEVPS 170
+ ++A + G+ +P+ T+ E+ S
Sbjct: 653 VLMVARSAAGEGQPAMITFRTSKEKTAS 680
Score = 34.3 bits (75), Expect = 2.4
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 446 TSRSPPRATHQFWVSASTRLGEGE-ATRVVTVLPSDSVPARITSFSRNIVTPWKENISLS 504
T P + + A + G+ E T +V VL S+ + ++ + + +
Sbjct: 277 TDSVDPADSGNYSCMAGNKSGDVEYVTYMVNVLEHASISKGL----QDQIVSLGATVHFT 332
Query: 505 CNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEV 564
C+ G PAP TW N + + R + +G L IS D G Y C +N G
Sbjct: 333 CDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG-LKISGVTVEDVGMYQCVADNGIGFMHS 391
Query: 565 TYTVEVK 571
T +E++
Sbjct: 392 TGRLEIE 398
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
VP P + + S+++ W + +GGSPI + + YKR +W + S+
Sbjct: 720 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 779
Query: 631 LP--NLWCGTRYQLYITAFNRIG 651
+ +L G+ Y+ + A N G
Sbjct: 780 VEVRSLEPGSTYKFRVIAINHYG 802
>AB209396-1|BAD92633.1| 675|Homo sapiens surface glycoprotein, Ig
superfamily member variant protein.
Length = 675
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPES-WPSTPQKVIVPGSV 127
VPE P + ++ ++W G SPI + V+YK S W + + P S
Sbjct: 131 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDI--PPSK 188
Query: 128 TSASVQNLQPATSYHLRIIAENRLGQ---SEPSQPVQV----TTTEEVPSGPPQDVRVEA 180
S V++L+P ++Y R+IA N G+ S S+P QV P P EA
Sbjct: 189 LSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEA 248
Query: 181 KSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTA 240
S T++++ W N I G+Y+ ++ +S++ + Y VEG +
Sbjct: 249 VSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDN---------DSDYKRDVVEG---S 296
Query: 241 RSRTTLSGLQKHAAYAVVVQAYN 263
+ + LQ +Y + +Q +N
Sbjct: 297 KQWHMIGHLQPETSYDIKMQCFN 319
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/85 (27%), Positives = 39/85 (45%)
Query: 667 VPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERV 726
VP P + T + T+V V +GG I F +EY+ M W + + + ++
Sbjct: 131 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 190
Query: 727 FSVSGLTPAAHYQLRITAHNNAGHA 751
V L P + Y+ R+ A N+ G +
Sbjct: 191 VEVRSLEPGSTYKFRVIAINHYGES 215
Score = 40.3 bits (90), Expect = 0.037
Identities = 47/224 (20%), Positives = 83/224 (37%), Gaps = 17/224 (7%)
Query: 168 VPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASG--PG 225
VP P + + S T + VTW P R I + V ++ + +++ ++ A P
Sbjct: 131 VPEAPDRPT-ISTASETSVYVTWIP--RANGGSPITAFKVEYKRMRTSNWLVAAEDIPPS 187
Query: 226 GASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSL 285
S VR++E T + R H +++ S P
Sbjct: 188 KLSVEVRSLEPGSTYKFRVIAIN---HYG-----ESFRSSASRPYQVVGFPNRFSSRPIT 239
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHT 345
P A+S + + W P N +QG+ + Y P TD + D + G
Sbjct: 240 GPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRP-TDSDNDSDYKRDVVEGSKQ 298
Query: 346 --TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTE-EDVPSA 386
+ L+ T+Y + + F G+ + + C T+ + VP A
Sbjct: 299 WHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGA 342
Score = 38.7 bits (86), Expect = 0.11
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 86 IQISWTQ-PYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHL 143
I + WT P + N+ PI + + Y+ S ++ +V GS + +LQP TSY +
Sbjct: 254 IMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDI 313
Query: 144 RIIAENRLGQSEPSQ-PVQVTTTEEVPSGPPQDVR 177
++ N G+SE S + T + VP V+
Sbjct: 314 KMQCFNEGGESEFSNVMICETKVKRVPGASEYPVK 348
Score = 33.5 bits (73), Expect = 4.3
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKR-EHGDWEELQVEAGTSEHV 630
VP P + + S+++ W + +GGSPI + + YKR +W + S+
Sbjct: 131 VPEAPDRPTISTASETSVYVTWIPRANGGSPITAFKVEYKRMRTSNWLVAAEDIPPSKLS 190
Query: 631 LP--NLWCGTRYQLYITAFNRIG 651
+ +L G+ Y+ + A N G
Sbjct: 191 VEVRSLEPGSTYKFRVIAINHYG 213
>AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein.
Length = 1189
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 19/217 (8%)
Query: 466 GEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGLE 525
G TRV+ P PA I + + C+ G P P +WT G GL+
Sbjct: 415 GPSPVTRVLLKAP----PAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQ 470
Query: 526 STLRKNVSSDGTLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVPPQPPILAVVDSY 585
+ V S+ +L + G++ CS N R + V V + P ++ V
Sbjct: 471 G--QAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYV-LGTSPHVVTNVSVV 527
Query: 586 A--DSLHLQWSDQGDGGSPILGYVINYK-------REHGDWEELQVEAGTSEHVLPNLWC 636
A ++ W DGG + + + Y R H DW L V G + ++P L
Sbjct: 528 ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQP 586
Query: 637 GTRYQLYITAFNRIGTGLPCDIVHAYTKG--TVPVKP 671
T+YQ + A N++G+G +IV + +G T P P
Sbjct: 587 HTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAP 623
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSDGTLTISMTQSADSGNYTCSVENI 558
E ++L C G P P TW + G L + +GTL I + SG YTC +
Sbjct: 162 EPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASST 221
Query: 559 HGRDEVTYTVEVKVPPQPPILAV 581
G T+ ++ V PP++ V
Sbjct: 222 EG--SATHATQLLV-LGPPVIVV 241
Score = 36.7 bits (81), Expect = 0.46
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPAT-TWTMNGVGLE 525
EG AT +L P I +N +++SL+C+ PA T +W + + +
Sbjct: 222 EGSATHATQLLVLG--PPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVF 279
Query: 526 --STL--RKNVSSDGTLTISMTQSADSGNYTCSVEN--IHGRD-----EVTYTVEV-KVP 573
S L R + DG+L + TQ D+G YTC N +H V Y +V +P
Sbjct: 280 HISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMP 339
Query: 574 PQPPI 578
P+ P+
Sbjct: 340 PETPL 344
Score = 36.7 bits (81), Expect = 0.46
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 19/142 (13%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYK---EAPESWPSTPQKVIVPGS 126
P + N+ V+ + +SW + G + + V Y + P+ + VP
Sbjct: 518 PHVVTNVSVV-ALPKGANVSWEPGFDGGY-LQRFSVWYTPLAKRPDRMHHDWVSLAVPVG 575
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQ-----PVQVTTTEEVPSGPPQDV----- 176
V LQP T Y ++A+N+LG S+ P + TT P PP ++
Sbjct: 576 AAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLS 635
Query: 177 ----RVEAKSSTELIVTWEPPQ 194
V ++ +++ W+PP+
Sbjct: 636 PPRGLVAVRTPRGVLLHWDPPE 657
>BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 1009
Score = 61.3 bits (142), Expect = 2e-08
Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
Query: 591 LQWSDQGDGGSPILGYVINYKREHGD---WEELQV-----EAGTSEHVLPNLWCGTRYQL 642
+QW GSPILGY + Y D E+L + T+E V+ +L GT Y++
Sbjct: 53 IQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTTEEVIGDLKPGTEYRV 112
Query: 643 YITAFNRIGTGLPCDIVHAYTKG----TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCG 697
I A+++ G G H T P P+ +I ++ + V + W +G
Sbjct: 113 SIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAP 172
Query: 698 ILYFVIEY-REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
I Y+ +E+ R +W + +Q V + GL P +YQ + A N+ G
Sbjct: 173 IQYYSVEFIRPDFDKKWTSIHERIQMDSMV--IKGLDPDTNYQFAVRAMNSHG 223
Score = 55.2 bits (127), Expect = 1e-06
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS----VT 128
P +I++ I W P SPI+ Y V Y E Q VP S T
Sbjct: 38 PLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTT 97
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE---VPSGPPQDVRVEAKSSTE 185
+ +L+P T Y + I A ++ G+ S P VTT + +P PQ V S +E
Sbjct: 98 EEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSE 157
Query: 186 LIVTWEP 192
+ ++W+P
Sbjct: 158 VALSWKP 164
Score = 48.8 bits (111), Expect = 1e-04
Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 15/207 (7%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
GPP D+++ A + T + W+ P+ ILGY V + E+ ++ ++ S
Sbjct: 36 GPPLDIKLGALNCTAFSIQWKMPRHP--GSPILGYTVFYSEVGADKSLQEQLHSVPLSRD 93
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL 290
+ T E + L+ Y V + AY+ + LPP A
Sbjct: 94 IPTTE--------EVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAP 145
Query: 291 Q---CNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL 347
Q +S V +SW+P G + +Q Y V + D+ ++ ++I +
Sbjct: 146 QQPHVIVVSDSEVALSWKPGASEG-SAPIQYYSVEFIR-PDFDKKWTSIHERIQMDSMVI 203
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAP 374
GL TNY V A + G R+ P
Sbjct: 204 KGLDPDTNYQFAVRAMNSHGPSPRSWP 230
Score = 44.0 bits (99), Expect = 0.003
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDA----VTKQI 340
PP ++ AL+ + + W+ P G + IL GY V Y+ V D E +++ I
Sbjct: 37 PPLDIKLGALNCTAFSIQWKMPRHPG-SPIL-GYTVFYSEVGADKSLQEQLHSVPLSRDI 94
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT-EED---VPSAPADIKAAVSS 396
+ L+ T Y V++ A++ AG G ++P + T +D P+AP V S
Sbjct: 95 PTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVS 154
Query: 397 RNKILVSWLPPSSPNGVLVGY 417
+++ +SW P +S + Y
Sbjct: 155 DSEVALSWKPGASEGSAPIQY 175
Score = 37.1 bits (82), Expect = 0.35
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 12/109 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA--GNSPIINYIVQY--KEAPESWPSTPQKVIVPG 125
P P+ VI + +SW +P A G++PI Y V++ + + W S +++
Sbjct: 142 PAAPQQPHVIVVSDSEVALSW-KPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERI---- 196
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTT---EEVPSG 171
+ S ++ L P T+Y + A N G S S P + T EE SG
Sbjct: 197 QMDSMVIKGLDPDTNYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEAGSG 245
Score = 35.5 bits (78), Expect = 1.1
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 6/101 (5%)
Query: 387 PADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI--EDGREEGTHKRMLSPS--TL 442
P DIK + + W P P ++GYT++ S + + +E H LS T
Sbjct: 38 PLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTT 97
Query: 443 SHETSRSPPRATHQFWVSASTRLGEG--EATRVVTVLPSDS 481
P ++ ++A ++ G+G + R VT L DS
Sbjct: 98 EEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDS 138
>AK075220-1|BAC11480.1| 760|Homo sapiens protein ( Homo sapiens
cDNA FLJ90739 fis, clone PLACE1010968, highly similar to
FAD104. ).
Length = 760
Score = 61.3 bits (142), Expect = 2e-08
Identities = 148/647 (22%), Positives = 235/647 (36%), Gaps = 72/647 (11%)
Query: 141 YHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNG 200
Y R+ A N +G S SQ V T +P P V A T + + W P+
Sbjct: 3 YTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKPE-GCSPE 60
Query: 201 NILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVVQ 260
++ Y + QE + N + YT + T+ L++ Y +
Sbjct: 61 EVITYTLEIQE-DENDNLF------HPKYTGEDLT--------CTVKNLKRSTQYKFRLT 105
Query: 261 AYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYR 320
A N+ D P P L ++S V W+PP G + IL+ Y
Sbjct: 106 ASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILK-YL 164
Query: 321 VTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVY 376
+ +TD GN +A ++ SG T T + L+ T Y + C + G + +
Sbjct: 165 L---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLP 219
Query: 377 CHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YTLYMSVIEDGREEGTHK 434
T P + ++K + + W P+S +G V Y++ M+ ED E H
Sbjct: 220 VRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYH- 278
Query: 435 RMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARITSFSRNIV 494
P L P ++F V A G G + V + + P + +
Sbjct: 279 ---GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKA------ 328
Query: 495 TPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSSDGTLT-ISMTQSADSG 549
P C VG +P ++ ++ L E + GT T + +
Sbjct: 329 -PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAA 387
Query: 550 NYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAV-----VDSYADS----LHLQWS 594
Y C ++ N G + V + P P L V +D+Y DS L L W
Sbjct: 388 QYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWE 447
Query: 595 DQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGL 654
+ D GS IL Y I+ GD + V T+ HV+ +L T Y++ I A N IG G
Sbjct: 448 EPCDNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPETTYRIRIQAINEIGAGP 501
Query: 655 PCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWR 714
+ A T+ P+ P+ + W DS + ++ ++ R
Sbjct: 502 FSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHAAEDIVYTLQLEDRNKR 559
Query: 715 LVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYNFTT 759
+S + + V LT Y RI A + AG Y F+T
Sbjct: 560 FIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFST 605
Score = 60.5 bits (140), Expect = 3e-08
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 30 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 85
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 86 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 145
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 146 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 189
Score = 45.2 bits (102), Expect = 0.001
Identities = 82/382 (21%), Positives = 142/382 (37%), Gaps = 37/382 (9%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+ + W P + + I Y +++ E ES ++I G+ T +++L PA Y R+
Sbjct: 339 VLVGWESPDSSGADISEYRLEWGEDEESL-----ELIYHGTDTRFEIRDLLPAAQYCCRL 393
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
A N+ G S+ V T P+ P V + L V E P +
Sbjct: 394 QAFNQAGAGPYSELVLCQT----PASAPDPV-------STLCVLEEEPLDAYPDSPSACL 442
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT--TLSGLQKHAAYAVVVQAYN 263
+ ++E N + ++A YT+ + + T + T + L Y + +QA N
Sbjct: 443 VLNWEEPCDNGSEILA-------YTIDLGDTSITVGNTTMHVMKDLLPETTYRIRIQAIN 495
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
+P LPP L+C A QS+++ W + + Y
Sbjct: 496 E-IGAGPFSQFIKAKTRPLPPLPP-RLECAAAGPQSLKLKWGDSNSKTH----AAEDIVY 549
Query: 324 APVTDWYGNEDAVTKQISGLHT-TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
+ N+ ++ HT + L +T YS + A + AG+G + T +
Sbjct: 550 TLQLE-DRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKS 608
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
VP + N + W S G V Y L + V GR E +K++
Sbjct: 609 VPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLV---GR-ESEYKQVYKGEEA 664
Query: 443 SHETSRSPPRATHQFWVSASTR 464
+ + S ++F V A R
Sbjct: 665 TFQISGLQTNTDYRFRVCACRR 686
Score = 42.3 bits (95), Expect = 0.009
Identities = 68/286 (23%), Positives = 107/286 (37%), Gaps = 41/286 (14%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPAT 139
D S + ++W +P S I+ Y + + I G+ T +++L P T
Sbjct: 436 DSPSACLVLNWEEPCDNGSEILAYTIDLGDTS----------ITVGNTTMHVMKDLLPET 485
Query: 140 SYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+Y +RI A N +G SQ ++ T +P PP+ + A L + W
Sbjct: 486 TYRIRIQAINEIGAGPFSQFIK-AKTRPLPPLPPR-LECAAAGPQSLKLKWGDSNSKTHA 543
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
+ Y + ++ N + I GP S+T + + L + Y+ +
Sbjct: 544 AEDIVYTLQLEDRNKR-FISIYRGP---SHTYK-------------VQRLTEFTCYSFRI 586
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPMRGR--NGIL 316
QA + + VP A + L S + WE P M+G N IL
Sbjct: 587 QAASEAGEGPFSETYTFSTTKSVPPTIK-APRVTQLEGNSCEILWETVPSMKGDPVNYIL 645
Query: 317 QGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
Q + Y E+A T QISGL T T+Y VCA
Sbjct: 646 QVLVGRESEYKQVYKGEEA-TFQISGLQTN-------TDYRFRVCA 683
Score = 41.1 bits (92), Expect = 0.021
Identities = 85/407 (20%), Positives = 142/407 (34%), Gaps = 39/407 (9%)
Query: 84 RTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+ + + W P + + + Y V+ E PE S + G +V NL P T Y
Sbjct: 242 KEVHLEWDVPASESGCEVSEYSVEMTE-PEDVASE----VYHGPELECTVGNLLPGTVYR 296
Query: 143 LRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE---LIVTWEPPQRDLWN 199
R+ A N G S ++TT +GPP + S T ++V WE P D
Sbjct: 297 FRVRALNDGGYGPYSDVSEITTA----AGPPGQCKAPCISCTPDGCVLVGWESP--DSSG 350
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
+I Y + + E + S LI G + +R + A R Y+ +V
Sbjct: 351 ADISEYRLEWGE-DEESLELIYHGT-DTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELV 408
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
E + + P C L +WE P G + Y
Sbjct: 409 LCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVL-------NWEEPCDNGSE--ILAY 459
Query: 320 RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
+ + GN + +H + L T Y + + A G G + + T
Sbjct: 460 TIDLGDTSITVGN--------TTMH-VMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKT 510
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
+P P ++ A + + + W +S +Y +ED R + P
Sbjct: 511 -RPLPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAED-IVYTLQLED-RNKRFISIYRGP 567
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
S +++ R + F + A++ GEG + T + SVP I
Sbjct: 568 SH-TYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTI 613
Score = 33.9 bits (74), Expect = 3.2
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 513 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 572
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 573 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWET 632
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 633 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 683
Score = 32.7 bits (71), Expect = 7.5
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISW-TQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
S + VP K RV + + +I W T P P+ NYI+Q ES K +
Sbjct: 604 STTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPV-NYILQVLVGRES----EYKQV 658
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENR 150
G + + LQ T Y R+ A R
Sbjct: 659 YKGEEATFQISGLQTNTDYRFRVCACRR 686
>AF464063-1|AAN86141.1| 282|Homo sapiens contactin 4a protein.
Length = 282
Score = 61.3 bits (142), Expect = 2e-08
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Query: 255 YAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNG 314
+ V V +N++ E+ P+ PP ++ +LS+ + V W P + R G
Sbjct: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNR-G 87
Query: 315 ILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAP 374
+QGY V Y D N + + T ++ L+ Y + V A+ +AG G +A
Sbjct: 88 RIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSAT 147
Query: 375 VYCHTEEDVPSAPADIKAAVSSRNKILVSW 404
V T + PS P SS +KI+++W
Sbjct: 148 VNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
Score = 59.3 bits (137), Expect = 8e-08
Identities = 54/238 (22%), Positives = 95/238 (39%), Gaps = 22/238 (9%)
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEP 192
+++ P + + +++ N G+ S V + EE P+ PP + + S+T++ V W
Sbjct: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
Query: 193 PQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKH 252
P + G I GY V + R + G S T ++ L+
Sbjct: 81 P-LEKNRGRIQGYEVKYWRHEDKEE------------NARKIRTVGNQTS-TKITNLKGS 126
Query: 253 AAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGR 312
Y + V+AYNS + PS PPG + N+ S + ++W+
Sbjct: 127 VLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDN 185
Query: 313 NGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTLS-GLRRYTNYSVTVCAFTAAGDG 369
++GY+V Y W N + T I T++ L +Y + + F+ GDG
Sbjct: 186 ESEVKGYKVLYR----W--NRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG 237
Score = 58.8 bits (136), Expect = 1e-07
Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISWTQPYAGN-SPIINYIVQYKEAPESWPSTPQKVI 122
S + + P +I + I++ W P N I Y V+Y E +K+
Sbjct: 52 SAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRH-EDKEENARKIR 110
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKS 182
G+ TS + NL+ + YHL + A N G S V VTT + PS PP ++ + S
Sbjct: 111 TVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSS 169
Query: 183 STELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLI 220
+++I+ W+ + + GY V ++ +ST +I
Sbjct: 170 DSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVI 207
Score = 35.1 bits (77), Expect = 1.4
Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 10/190 (5%)
Query: 353 YTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPS-APADIKAAVSSRNKILVSWLPPSSPN 411
++ + V V F G+G + ++ E+ P+ PA I A S I V W P N
Sbjct: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKN 85
Query: 412 -GVLVGYTLYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEA 470
G + GY + ED +EE K + S + + + V A G G +
Sbjct: 86 RGRIQGYEVKYWRHED-KEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
Query: 471 TRVVTVL----PSDSVPARI--TSFSRNIVTPWKENISLSCNKVGVPAPATTWTMNGVGL 524
+ V V P P I S I+ W + +L N+ V + N
Sbjct: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD-NESEVKGYKVLYRWNRQSS 203
Query: 525 ESTLRKNVSS 534
S + N +S
Sbjct: 204 TSVIETNKTS 213
Score = 33.5 bits (73), Expect = 4.3
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 564 VTYTVEVKVPPQPPILAVVDSY-ADSLHLQWSDQGDGG-SPILGYVINYKREHGDWEE-- 619
V Y+ E + P +PP S A + + W+ + I GY + Y R H D EE
Sbjct: 49 VVYSAEEE-PTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR-HEDKEENA 106
Query: 620 --LQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKP 671
++ + + NL Y L + A+N GTG V+ T+ P +P
Sbjct: 107 RKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQP 160
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/170 (28%), Positives = 70/170 (41%), Gaps = 11/170 (6%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGL----ESTLRKNVSS----DGTLTISMTQSADSGN 550
+ + L C G P P TW + S+ VSS + TL I DSG
Sbjct: 789 DTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGI 848
Query: 551 YTCSVENIHGRDEVTYTVEVK-VPPQPPILAVVDSYADSLHLQW-SDQGDGGSPILGYVI 608
YTC N HG + TV+V+ VP P + S+ L+W G I GY +
Sbjct: 849 YTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTV 908
Query: 609 NYKREHGD-WEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTGLPCD 657
Y+ E W++ + V+ +L G YQ ++A N G LP +
Sbjct: 909 EYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSE 958
Score = 41.1 bits (92), Expect = 0.021
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 6/101 (5%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYA-GNSPIINYIVQYKE-APESWPSTPQKVIVPGS 126
VP P ++ ++ + W P + GN I Y V+Y+E + W Q+ +
Sbjct: 871 VPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIW----QQSVASTL 926
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE 167
T +++L P Y R+ A N G S PS+P + E
Sbjct: 927 DTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVRLPE 967
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 681 TTTVTVWLDSWGDGGCGILYFVIEYREMSQPQWRLVSNSVQAT-ERVFSVSGLTPAAHYQ 739
T+ + WL G C I + +EYRE W+ SV +T + + L+P YQ
Sbjct: 886 TSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQ---QSVASTLDTYLVIEDLSPGCPYQ 942
Query: 740 LRITAHNNAGHAL 752
R++A N G +L
Sbjct: 943 FRVSASNPWGISL 955
Score = 33.5 bits (73), Expect = 4.3
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 10/90 (11%)
Query: 381 EDVPSAPADIKAAVSSRNKILVSWLPPSSP-NGVLVGYTLYMSVIEDGREEGTHKRMLS- 438
+ VP+AP A S +++ WLPPSS N + GYT+ + REEG+ S
Sbjct: 869 QGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTV------EYREEGSQIWQQSV 922
Query: 439 PSTLSH--ETSRSPPRATHQFWVSASTRLG 466
STL P +QF VSAS G
Sbjct: 923 ASTLDTYLVIEDLSPGCPYQFRVSASNPWG 952
>AY358367-1|AAQ88733.1| 625|Homo sapiens YVTM2421 protein.
Length = 625
Score = 60.9 bits (141), Expect = 2e-08
Identities = 85/365 (23%), Positives = 137/365 (37%), Gaps = 39/365 (10%)
Query: 77 RVIDQQSRTIQISWTQPYA---GNSPIINYIVQYKEA-PESWPSTPQKVIVPGSVTSASV 132
+V + Q+R + +SW P G +++ Y+ A + K+I G ++
Sbjct: 279 QVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNL 338
Query: 133 QNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGP-PQDVRVEAKSSTELIVTWE 191
++L+PAT YH+R+ A + S+PV TT P P P + +KSS L + W+
Sbjct: 339 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSS--LTLQWK 396
Query: 192 PPQRDLWNGN-ILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQ 250
P + NG+ I Y + + E N SG + ++ L+ L
Sbjct: 397 AP---IDNGSKITNYLLEWDEGKRN------SGFRQCFF---------GSQKHCKLTKLC 438
Query: 251 KHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMR 310
Y + A N + ++P +P A V + W P
Sbjct: 439 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKP--- 494
Query: 311 GRNGILQGYRVTYAPVTDWYGNEDAVTKQISG--LHTTLSGLRRYTNYSVTVCAFTAAGD 368
G +TY N++ + +G L T+ L+R T Y + A G
Sbjct: 495 --EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGK 552
Query: 369 GVRAAPVYCHTEEDVPSAPAD--IKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIED 426
+ + C T D P P +K V+S V W PP G + Y+ I D
Sbjct: 553 SCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHG-FSVKWDPPKDNGGSEI--LKYLLEITD 609
Query: 427 GREEG 431
G EG
Sbjct: 610 GNSEG 614
Score = 60.5 bits (140), Expect = 3e-08
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 7/152 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 470 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 525
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 526 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 585
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTV 218
V W+PP +D IL Y + + NS V
Sbjct: 586 SVKWDPP-KDNGGSEILKYLLEITDGNSEGEV 616
Score = 58.0 bits (134), Expect = 2e-07
Identities = 72/295 (24%), Positives = 113/295 (38%), Gaps = 17/295 (5%)
Query: 467 EGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNK-VGVPAPAT-TWTMNGVGL 524
E E RV +L P +R +V W + LSC G+ P + ++ G
Sbjct: 262 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGR 321
Query: 525 ESTLRKNVSSDGTLTISMTQSADSGNYTCSV----ENIHGR--DEVTYTVEVKVP--PQP 576
+ K + S L ++ + +Y V ++ G + V++T P P P
Sbjct: 322 DGKY-KIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFP 380
Query: 577 PILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHV-LPNLW 635
P LA SL LQW D GS I Y++ + + Q G+ +H L L
Sbjct: 381 PKLA--HRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLC 438
Query: 636 CGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDG 694
Y + A N IGT V YT G +P P +++ T VT+ W G
Sbjct: 439 PAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCS 498
Query: 695 GCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
++ + +E +E L + +V L + Y+ R+TA N G
Sbjct: 499 PEEVITYTLEIQEDEND--NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEG 551
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/248 (22%), Positives = 91/248 (36%), Gaps = 20/248 (8%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTS 129
PE P ++ + ++ + W P S I NY++++ E ++ + GS
Sbjct: 375 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKR---NSGFRQCFFGSQKH 431
Query: 130 ASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVT 189
+ L PA Y R+ A N +G S SQ V T +P P V A T + +
Sbjct: 432 CKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQ 490
Query: 190 WEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGL 249
W P+ ++ Y + QE + N + YT + T+ L
Sbjct: 491 WSKPE-GCSPEEVITYTLEIQE-DENDNLF------HPKYTGEDL--------TCTVKNL 534
Query: 250 QKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPM 309
++ Y + A N+ D P P L ++S V W+PP
Sbjct: 535 KRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKD 594
Query: 310 RGRNGILQ 317
G + IL+
Sbjct: 595 NGGSEILK 602
Score = 34.7 bits (76), Expect = 1.8
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 13/154 (8%)
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSP--ILGYVINYKREHGD 616
+ ++ V YT+ +P P +V + + LQWS + +G SP ++ Y + + + D
Sbjct: 458 YSQEVVCYTLG-NIPQMPSAPRLVRAGITWVTLQWS-KPEGCSPEEVITYTLEIQEDEND 515
Query: 617 WEELQVEAGTSEHV---LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVK 670
L T E + + NL T+Y+ +TA N G P +++ T + P +
Sbjct: 516 --NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTR 573
Query: 671 PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIE 704
P +T + +V W +GG IL +++E
Sbjct: 574 PLVKGPVTSHGFSVK-WDPPKDNGGSEILKYLLE 606
>AK096474-1|BAC04800.1| 403|Homo sapiens protein ( Homo sapiens
cDNA FLJ39155 fis, clone OCBBF2001983. ).
Length = 403
Score = 60.9 bits (141), Expect = 2e-08
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 16/173 (9%)
Query: 591 LQWSDQGDGGSPILGYVINYKREHGD---WEELQV-----EAGTSEHVLPNLWCGTRYQL 642
+QW GSPILGY + Y D E+L + T+E V+ +L GT Y +
Sbjct: 53 IQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTTEEVIGDLKPGTEYHV 112
Query: 643 YITAFNRIGTGLPCDIVHAYTKG----TVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCG 697
I A+++ G G H T P P+ +I ++ + V + W +G
Sbjct: 113 SIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAP 172
Query: 698 ILYFVIEY-REMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
I Y+ +E+ R +W + +Q V + GL P +YQ + A N+ G
Sbjct: 173 IQYYSVEFIRPDFDKKWTSIHERIQMDSMV--IKGLDPDTNYQFAVRAMNSHG 223
Score = 58.4 bits (135), Expect = 1e-07
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 7/127 (5%)
Query: 73 PKNIRVIDQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGS----VT 128
P +I++ I W P SPI+ Y V Y E Q VP S T
Sbjct: 38 PLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTT 97
Query: 129 SASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEE---VPSGPPQDVRVEAKSSTE 185
+ +L+P T YH+ I A ++ G+ S P VTT + +P PQ V S +E
Sbjct: 98 EEVIGDLKPGTEYHVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSE 157
Query: 186 LIVTWEP 192
+ ++W+P
Sbjct: 158 VALSWKP 164
Score = 48.4 bits (110), Expect = 1e-04
Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 15/207 (7%)
Query: 171 GPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGASYT 230
GPP D+++ A + T + W+ P+ ILGY V + E+ ++ ++ S
Sbjct: 36 GPPLDIKLGALNCTAFSIQWKMPRHP--GSPILGYTVFYSEVGADKSLQEQLHSVPLSRD 93
Query: 231 VRTVEGAGTARSRTTLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGAL 290
+ T E + L+ Y V + AY+ + LPP A
Sbjct: 94 IPTTE--------EVIGDLKPGTEYHVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAP 145
Query: 291 Q---CNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQISGLHTTL 347
Q +S V +SW+P G + +Q Y V + D+ ++ ++I +
Sbjct: 146 QQPHVIVVSDSEVALSWKPGASEG-SAPIQYYSVEFIR-PDFDKKWTSIHERIQMDSMVI 203
Query: 348 SGLRRYTNYSVTVCAFTAAGDGVRAAP 374
GL TNY V A + G R+ P
Sbjct: 204 KGLDPDTNYQFAVRAMNSHGPSPRSWP 230
Score = 44.0 bits (99), Expect = 0.003
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 286 PPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTYAPV-TDWYGNEDA----VTKQI 340
PP ++ AL+ + + W+ P G + IL GY V Y+ V D E +++ I
Sbjct: 37 PPLDIKLGALNCTAFSIQWKMPRHPG-SPIL-GYTVFYSEVGADKSLQEQLHSVPLSRDI 94
Query: 341 SGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT-EED---VPSAPADIKAAVSS 396
+ L+ T Y V++ A++ AG G ++P + T +D P+AP V S
Sbjct: 95 PTTEEVIGDLKPGTEYHVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVS 154
Query: 397 RNKILVSWLPPSSPNGVLVGY 417
+++ +SW P +S + Y
Sbjct: 155 DSEVALSWKPGASEGSAPIQY 175
Score = 37.1 bits (82), Expect = 0.35
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 12/109 (11%)
Query: 70 PEMPKNIRVIDQQSRTIQISWTQPYA--GNSPIINYIVQY--KEAPESWPSTPQKVIVPG 125
P P+ VI + +SW +P A G++PI Y V++ + + W S +++
Sbjct: 142 PAAPQQPHVIVVSDSEVALSW-KPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERI---- 196
Query: 126 SVTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTT---EEVPSG 171
+ S ++ L P T+Y + A N G S S P + T EE SG
Sbjct: 197 QMDSMVIKGLDPDTNYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEAGSG 245
Score = 35.1 bits (77), Expect = 1.4
Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 387 PADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVI--EDGREEGTHKRMLSPS--TL 442
P DIK + + W P P ++GYT++ S + + +E H LS T
Sbjct: 38 PLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTT 97
Query: 443 SHETSRSPPRATHQFWVSASTRLGEG--EATRVVTVLPSDS 481
P + ++A ++ G+G + R VT L DS
Sbjct: 98 EEVIGDLKPGTEYHVSIAAYSQAGKGRLSSPRHVTTLSQDS 138
>BC033635-1|AAH33635.1| 753|Homo sapiens FNDC3B protein protein.
Length = 753
Score = 60.5 bits (140), Expect = 3e-08
Identities = 45/165 (27%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 69 VPEMPKNIRVIDQQSRTIQISWTQPYAGNSP--IINYIVQYKEAPESWPSTPQKVIVPGS 126
+P+MP R++ + + W++P G SP +I Y ++ +E P+ G
Sbjct: 23 IPQMPSAPRLVRAGITWVTLQWSKP-EGCSPEEVITYTLEIQEDENDNLFHPKYT---GE 78
Query: 127 VTSASVQNLQPATSYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTEL 186
+ +V+NL+ +T Y R+ A N G+S PS+ + TT+ + P P + + +S
Sbjct: 79 DLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGF 138
Query: 187 IVTWEPPQRDLWNGNILGYYVGFQELNSNSTVLIASGPGGAS-YT 230
V W+PP +D IL Y + + NS + + G A+ YT
Sbjct: 139 SVKWDPP-KDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYT 182
Score = 56.0 bits (129), Expect = 7e-07
Identities = 124/543 (22%), Positives = 200/543 (36%), Gaps = 55/543 (10%)
Query: 245 TLSGLQKHAAYAVVVQAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSW 304
T+ L++ Y + A N+ D P P L ++S V W
Sbjct: 83 TVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKW 142
Query: 305 EPPPMRGRNGILQGYRVTYAPVTDWYGNEDAVTKQI--SGLHT--TLSGLRRYTNYSVTV 360
+PP G + IL+ Y + +TD GN +A ++ SG T T + L+ T Y +
Sbjct: 143 DPPKDNGGSEILK-YLL---EITD--GNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRA 196
Query: 361 CAFTAAGDGVRAAPVYCHTEEDVPSAPADIKAAVSSRNK-ILVSWLPPSSPNGVLVG-YT 418
C + G + + T P + ++K + + W P+S +G V Y+
Sbjct: 197 CCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYS 256
Query: 419 LYMSVIEDGREEGTHKRMLSPSTLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLP 478
+ M+ ED E H P L P ++F V A G G + V +
Sbjct: 257 VEMTEPEDVASEVYH----GPE-LECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITT 311
Query: 479 SDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWT-MNGVGL---ESTLRKNVSS 534
+ P + + P C VG +P ++ ++ L E +
Sbjct: 312 AAGPPGQCKA-------PCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIY 364
Query: 535 DGTLT-ISMTQSADSGNYTCSVE--NIHGRDEVTYTVEVKVPPQPP----ILAV-----V 582
GT T + + Y C ++ N G + V + P P L V +
Sbjct: 365 HGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPL 424
Query: 583 DSYADS----LHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEHVLPNLWCGT 638
D+Y DS L L W + + GS IL Y I+ GD + V T+ HV+ +L T
Sbjct: 425 DAYPDSPSACLVLNWEEPCNNGSEILAYTIDL----GD-TSITV-GNTTMHVMKDLLPET 478
Query: 639 RYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDSWGDGGCGI 698
Y++ I A N IG G + A T+ P+ P+ + W DS +
Sbjct: 479 TYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS--NSKTHA 536
Query: 699 LYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAGHA--LALYN 756
++ ++ R +S + + V LT Y RI A + AG Y
Sbjct: 537 AEDIVYTLQLEDRNKRFIS-IYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYT 595
Query: 757 FTT 759
F+T
Sbjct: 596 FST 598
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/203 (26%), Positives = 92/203 (45%), Gaps = 18/203 (8%)
Query: 559 HGRDEVTYTVEVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSP--ILGYVINYKREHGD 616
+ ++ V YT+ +P P +V + + LQWS + +G SP ++ Y + + + D
Sbjct: 11 YSQEVVCYTLG-NIPQMPSAPRLVRAGITWVTLQWS-KPEGCSPEEVITYTLEIQEDEND 68
Query: 617 WEELQVEAGTSEHV---LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYT---KGTVPVK 670
L T E + + NL T+Y+ +TA N G P +++ T + P +
Sbjct: 69 --NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTR 126
Query: 671 PKHSQMITLNTTTVTVWLDSWGDGGCGILYFVIEYREMSQP--QWRLVSNSVQATERVFS 728
P +T + +V W +GG IL +++E + + QW V+ S ATE F
Sbjct: 127 PLVKGPVTSHGFSVK-WDPPKDNGGSEILKYLLEITDGNSEANQWE-VAYSGSATEYTF- 183
Query: 729 VSGLTPAAHYQLRITAHNNAGHA 751
+ L P Y+LR + GH+
Sbjct: 184 -THLKPGTLYKLRACCISTGGHS 205
Score = 45.6 bits (103), Expect = 0.001
Identities = 82/382 (21%), Positives = 143/382 (37%), Gaps = 37/382 (9%)
Query: 86 IQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYHLRI 145
+ + W P + + I Y +++ E ES ++I G+ T +++L PA Y R+
Sbjct: 332 VLVGWESPDSSGADISEYRLEWGEDEESL-----ELIYHGTDTRFEIRDLLPAAQYCCRL 386
Query: 146 IAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWNGNILGY 205
A N+ G S+ V T P+ P V + L V E P +
Sbjct: 387 QAFNQAGAGPYSELVLCQT----PASAPDPV-------STLCVLEEEPLDAYPDSPSACL 435
Query: 206 YVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRT--TLSGLQKHAAYAVVVQAYN 263
+ ++E +N + ++A YT+ + + T + T + L Y + +QA N
Sbjct: 436 VLNWEEPCNNGSEILA-------YTIDLGDTSITVGNTTMHVMKDLLPETTYRIRIQAIN 488
Query: 264 SRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGYRVTY 323
+P LPP L+C A QS+++ W + + Y
Sbjct: 489 E-IGAGPFSQFIKAKTRPLPPLPP-RLECAAAGPQSLKLKWGDSNSKTH----AAEDIVY 542
Query: 324 APVTDWYGNEDAVTKQISGLHT-TLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEED 382
+ N+ ++ HT + L +T YS + A + AG+G + T +
Sbjct: 543 TLQLE-DRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKS 601
Query: 383 VPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSPSTL 442
VP + N + W S G V Y L + V GR E +K++
Sbjct: 602 VPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLV---GR-ESEYKQVYKGEEA 657
Query: 443 SHETSRSPPRATHQFWVSASTR 464
+ + S ++F V A R
Sbjct: 658 TFQISGLQTNTDYRFRVCACRR 679
Score = 42.3 bits (95), Expect = 0.009
Identities = 68/286 (23%), Positives = 107/286 (37%), Gaps = 41/286 (14%)
Query: 80 DQQSRTIQISWTQPYAGNSPIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPAT 139
D S + ++W +P S I+ Y + + I G+ T +++L P T
Sbjct: 429 DSPSACLVLNWEEPCNNGSEILAYTIDLGDTS----------ITVGNTTMHVMKDLLPET 478
Query: 140 SYHLRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTELIVTWEPPQRDLWN 199
+Y +RI A N +G SQ ++ T +P PP+ + A L + W
Sbjct: 479 TYRIRIQAINEIGAGPFSQFIK-AKTRPLPPLPPR-LECAAAGPQSLKLKWGDSNSKTHA 536
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
+ Y + ++ N + I GP S+T + + L + Y+ +
Sbjct: 537 AEDIVYTLQLEDRNKR-FISIYRGP---SHTYK-------------VQRLTEFTCYSFRI 579
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEP-PPMRGR--NGIL 316
QA + + VP A + L S + WE P M+G N IL
Sbjct: 580 QAASEAGEGPFSETYTFSTTKSVPPTIK-APRVTQLEGNSCEILWETVPSMKGDPVNYIL 638
Query: 317 QGYRVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCA 362
Q + Y E+A T QISGL T T+Y VCA
Sbjct: 639 QVLVGRESEYKQVYKGEEA-TFQISGLQTN-------TDYRFRVCA 676
Score = 41.5 bits (93), Expect = 0.016
Identities = 85/407 (20%), Positives = 142/407 (34%), Gaps = 39/407 (9%)
Query: 84 RTIQISWTQPYAGNS-PIINYIVQYKEAPESWPSTPQKVIVPGSVTSASVQNLQPATSYH 142
+ + + W P + + + Y V+ E PE S + G +V NL P T Y
Sbjct: 235 KEVHLEWDVPASESGCEVSEYSVEMTE-PEDVASE----VYHGPELECTVGNLLPGTVYR 289
Query: 143 LRIIAENRLGQSEPSQPVQVTTTEEVPSGPPQDVRVEAKSSTE---LIVTWEPPQRDLWN 199
R+ A N G S ++TT +GPP + S T ++V WE P D
Sbjct: 290 FRVRALNDGGYGPYSDVSEITTA----AGPPGQCKAPCISCTPDGCVLVGWESP--DSSG 343
Query: 200 GNILGYYVGFQELNSNSTVLIASGPGGASYTVRTVEGAGTARSRTTLSGLQKHAAYAVVV 259
+I Y + + E + S LI G + +R + A R Y+ +V
Sbjct: 344 ADISEYRLEWGE-DEESLELIYHGT-DTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELV 401
Query: 260 QAYNSRXXXXXXXXXXXXXMEDVPSLPPGALQCNALSSQSVRVSWEPPPMRGRNGILQGY 319
E + + P C L +WE P G + Y
Sbjct: 402 LCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVL-------NWEEPCNNGSE--ILAY 452
Query: 320 RVTYAPVTDWYGNEDAVTKQISGLHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHT 379
+ + GN + +H + L T Y + + A G G + + T
Sbjct: 453 TIDLGDTSITVGN--------TTMH-VMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKT 503
Query: 380 EEDVPSAPADIKAAVSSRNKILVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRMLSP 439
+P P ++ A + + + W +S +Y +ED R + P
Sbjct: 504 -RPLPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAED-IVYTLQLED-RNKRFISIYRGP 560
Query: 440 STLSHETSRSPPRATHQFWVSASTRLGEGEATRVVTVLPSDSVPARI 486
S +++ R + F + A++ GEG + T + SVP I
Sbjct: 561 SH-TYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTI 606
Score = 36.7 bits (81), Expect = 0.46
Identities = 67/339 (19%), Positives = 116/339 (34%), Gaps = 21/339 (6%)
Query: 343 LHTTLSGLRRYTNYSVTVCAFTAAGDGVRAAPVYCHTEEDVPSAPAD--IKAAVSSRNKI 400
L T+ L+R T Y + A G + + C T D P P +K V+S
Sbjct: 80 LTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHG-F 138
Query: 401 LVSWLPPSSPNGVLVGYTLYMSVIEDGREEGTHKRM-LSPSTLSHETSRSPPRATHQFWV 459
V W PP G + Y+ I DG E + S S + + P ++
Sbjct: 139 SVKWDPPKDNGGSEI--LKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRA 196
Query: 460 SASTRLGEGEATRVVTVLPSDSVPARITSFSRNIVTPWKENISLSCNKVGVPAPATTWTM 519
+ G + + + V P + R + P + + L + VPA + +
Sbjct: 197 CCISTGGHSQCSESLPVRTLSIAPGQCRP-PRVLGRPKHKEVHLEWD---VPASESGCEV 252
Query: 520 NGVGLESTLRKNVSSDG------TLTISMTQSADSGNYTCSVENIHGRDEVTYTVEVKVP 573
+ +E T ++V+S+ T+ + N G + E+
Sbjct: 253 SEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTA 312
Query: 574 PQPP---ILAVVDSYADSLHL-QWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSEH 629
PP + D L W G+ I Y + + E + EL +
Sbjct: 313 AGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRLEW-GEDEESLELIYHGTDTRF 371
Query: 630 VLPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVP 668
+ +L +Y + AFN+ G G ++V T + P
Sbjct: 372 EIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAP 410
Score = 33.9 bits (74), Expect = 3.2
Identities = 36/174 (20%), Positives = 67/174 (38%), Gaps = 4/174 (2%)
Query: 572 VPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKREHGDWEELQVEAGTSE-HV 630
+PP PP L + SL L+W D V + E + + + G S +
Sbjct: 506 LPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYK 565
Query: 631 LPNLWCGTRYQLYITAFNRIGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTVWLDS 690
+ L T Y I A + G G + T +VP K ++ L + + ++
Sbjct: 566 VQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWET 625
Query: 691 WGDGGCGILYFVIEYREMSQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITA 744
+ ++++ + +++ V +AT F +SGL Y+ R+ A
Sbjct: 626 VPSMKGDPVNYILQVLVGRESEYKQVYKGEEAT---FQISGLQTNTDYRFRVCA 676
Score = 33.5 bits (73), Expect = 4.3
Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 3/101 (2%)
Query: 650 IGTGLPCDIVHAYTKGTVPVKPKHSQMITLNTTTVTV-WLDSWGDGGCGILYFVIEYREM 708
IGT V YT G +P P +++ T VT+ W G ++ + +E +E
Sbjct: 6 IGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQED 65
Query: 709 SQPQWRLVSNSVQATERVFSVSGLTPAAHYQLRITAHNNAG 749
L + +V L + Y+ R+TA N G
Sbjct: 66 END--NLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEG 104
Score = 32.7 bits (71), Expect = 7.5
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 6/88 (6%)
Query: 64 SLSHQVPEMPKNIRVIDQQSRTIQISW-TQPYAGNSPIINYIVQYKEAPESWPSTPQKVI 122
S + VP K RV + + +I W T P P+ NYI+Q ES K +
Sbjct: 597 STTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPV-NYILQVLVGRES----EYKQV 651
Query: 123 VPGSVTSASVQNLQPATSYHLRIIAENR 150
G + + LQ T Y R+ A R
Sbjct: 652 YKGEEATFQISGLQTNTDYRFRVCACRR 679
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
Length = 1960
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCS 554
++++L+C PA TW+ +G LES+ R +S+ LTI + + D G YTCS
Sbjct: 1470 QSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCS 1529
Query: 555 VENIHGRDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKRE 613
V N G T + + + P P + + YAD + L W G P+ Y++ E
Sbjct: 1530 VSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYG-PVT-YIVQCSLE 1587
Query: 614 HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
G W L + ++ L G Y ++ G G
Sbjct: 1588 GGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMG 1627
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLE----STLRKNVSSDGTLTISMTQSADSGNYTCS 554
E + L+C G P P +W +G ++ L ++ L + DSG Y C
Sbjct: 21 ETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCF 80
Query: 555 VENIHGRDEVTYTVEVKVPPQ 575
+ G + V+VPP+
Sbjct: 81 AASAAGNCSTLGKILVQVPPR 101
Score = 36.7 bits (81), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGR 561
G P P+ TW + V L + R + +GT L + S D+G YTC +N G+
Sbjct: 374 GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQ 429
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCS 554
++++L+C PA TW+ +G LES+ R +S+ LTI + + D G YTCS
Sbjct: 2094 QSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCS 2153
Query: 555 VENIHGRDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKRE 613
V N G T + + + P P + + YAD + L W G P+ Y++ E
Sbjct: 2154 VSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYG-PVT-YIVQCSLE 2211
Query: 614 HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
G W L + ++ L G Y ++ G G
Sbjct: 2212 GGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMG 2251
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLE----STLRKNVSSDGTLTISMTQSADSGNYTCS 554
E + L+C G P P +W +G ++ L ++ L + DSG Y C
Sbjct: 645 ETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCF 704
Query: 555 VENIHGRDEVTYTVEVKVPPQ 575
+ G + V+VPP+
Sbjct: 705 AASAAGNCSTLGKILVQVPPR 725
Score = 36.7 bits (81), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGR 561
G P P+ TW + V L + R + +GT L + S D+G YTC +N G+
Sbjct: 998 GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQ 1053
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCS 554
++++L+C PA TW+ +G LES+ R +S+ LTI + + D G YTCS
Sbjct: 2094 QSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCS 2153
Query: 555 VENIHGRDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKRE 613
V N G T + + + P P + + YAD + L W G P+ Y++ E
Sbjct: 2154 VSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYG-PVT-YIVQCSLE 2211
Query: 614 HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
G W L + ++ L G Y ++ G G
Sbjct: 2212 GGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMG 2251
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLE----STLRKNVSSDGTLTISMTQSADSGNYTCS 554
E + L+C G P P +W +G ++ L ++ L + DSG Y C
Sbjct: 645 ETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCF 704
Query: 555 VENIHGRDEVTYTVEVKVPPQ 575
+ G + V+VPP+
Sbjct: 705 AASAAGNCSTLGKILVQVPPR 725
Score = 36.7 bits (81), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGR 561
G P P+ TW + V L + R + +GT L + S D+G YTC +N G+
Sbjct: 998 GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQ 1053
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 7/160 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLESTLRKNVSSD----GTLTISMTQSADSGNYTCS 554
++++L+C PA TW+ +G LES+ R +S+ LTI + + D G YTCS
Sbjct: 2094 QSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCS 2153
Query: 555 VENIHGRDEVTYTV-EVKVPPQPPILAVVDSYADSLHLQWSDQGDGGSPILGYVINYKRE 613
V N G T + + + P P + + YAD + L W G P+ Y++ E
Sbjct: 2154 VSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYG-PVT-YIVQCSLE 2211
Query: 614 HGDWEELQVEAGTSEHVLPNLWCGTRYQLYITAFNRIGTG 653
G W L + ++ L G Y ++ G G
Sbjct: 2212 GGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMG 2251
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 499 ENISLSCNKVGVPAPATTWTMNGVGLE----STLRKNVSSDGTLTISMTQSADSGNYTCS 554
E + L+C G P P +W +G ++ L ++ L + DSG Y C
Sbjct: 645 ETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCF 704
Query: 555 VENIHGRDEVTYTVEVKVPPQ 575
+ G + V+VPP+
Sbjct: 705 AASAAGNCSTLGKILVQVPPR 725
Score = 36.7 bits (81), Expect = 0.46
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 509 GVPAPATTWTMNGVGLESTLRKNVSSDGT---LTISMTQSADSGNYTCSVENIHGR 561
G P P+ TW + V L + R + +GT L + S D+G YTC +N G+
Sbjct: 998 GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQ 1053
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.313 0.129 0.385
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 164,992,427
Number of Sequences: 224733
Number of extensions: 7179061
Number of successful extensions: 33616
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 927
Number of HSP's that attempted gapping in prelim test: 20246
Number of HSP's gapped (non-prelim): 9118
length of query: 1104
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1006
effective length of database: 51,211,004
effective search space: 51518270024
effective search space used: 51518270024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 70 (32.3 bits)
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