Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001923-TA|BGIBMGA001923-PA|IPR013098|Immunoglobulin
I-set, IPR013151|Immunoglobulin, IPR003599|Immunoglobulin subtype,
IPR003598|Immunoglobulin subtype 2, IPR007110|Immunoglobulin-like
(366 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 156 1e-37
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 155 2e-37
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 155 2e-37
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 155 2e-37
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 154 4e-37
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 152 2e-36
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 152 2e-36
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 151 3e-36
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 97 7e-20
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 95 3e-19
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 95 3e-19
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 95 3e-19
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 94 8e-19
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 93 1e-18
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 93 1e-18
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 86 2e-16
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 86 2e-16
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 85 3e-16
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 85 3e-16
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 85 3e-16
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 85 4e-16
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 85 5e-16
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 84 9e-16
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 83 1e-15
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 83 1e-15
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 83 1e-15
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 83 1e-15
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 83 1e-15
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 83 1e-15
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 82 3e-15
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 81 5e-15
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 81 5e-15
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 81 5e-15
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 81 8e-15
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 79 2e-14
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 79 2e-14
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 79 2e-14
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 79 2e-14
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 79 2e-14
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 79 2e-14
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 79 2e-14
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 79 3e-14
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 79 3e-14
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 79 3e-14
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 79 3e-14
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 79 3e-14
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 79 3e-14
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 78 6e-14
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 78 6e-14
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 77 7e-14
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 77 1e-13
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 77 1e-13
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 77 1e-13
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 75 4e-13
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 75 5e-13
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 74 9e-13
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 74 9e-13
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 73 1e-12
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 73 1e-12
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 73 1e-12
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 73 2e-12
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 73 2e-12
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 73 2e-12
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 73 2e-12
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 73 2e-12
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 73 2e-12
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 72 4e-12
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 70 1e-11
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 70 1e-11
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 70 1e-11
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 69 2e-11
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 69 3e-11
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 69 3e-11
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 69 3e-11
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 69 3e-11
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 68 5e-11
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 68 6e-11
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 68 6e-11
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 68 6e-11
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 68 6e-11
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 68 6e-11
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 68 6e-11
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 68 6e-11
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 68 6e-11
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 68 6e-11
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 68 6e-11
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 68 6e-11
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 68 6e-11
AL163283-1|CAB90464.1| 169|Homo sapiens human CHD2-52 down synd... 67 8e-11
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 67 1e-10
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 66 1e-10
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 66 1e-10
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 66 1e-10
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 66 2e-10
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 66 2e-10
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 66 2e-10
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 66 2e-10
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 66 2e-10
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 66 2e-10
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 66 2e-10
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 66 2e-10
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 66 2e-10
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 66 2e-10
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 66 2e-10
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 66 2e-10
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 66 2e-10
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 66 2e-10
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 65 3e-10
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 65 3e-10
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 65 4e-10
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 65 4e-10
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 65 4e-10
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 65 4e-10
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 65 4e-10
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 65 4e-10
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 64 6e-10
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 64 6e-10
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 64 6e-10
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 64 6e-10
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 62 2e-09
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 62 2e-09
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 62 2e-09
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 62 4e-09
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 61 5e-09
BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5 prot... 61 5e-09
AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein pr... 61 5e-09
AC079227-1|AAY40948.1| 274|Homo sapiens unknown protein. 61 5e-09
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 61 5e-09
AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein. 61 5e-09
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 61 7e-09
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 60 9e-09
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 60 2e-08
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 60 2e-08
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 60 2e-08
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 60 2e-08
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 59 3e-08
AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein. 58 5e-08
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 58 6e-08
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 58 6e-08
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 57 9e-08
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 57 9e-08
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 57 9e-08
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 57 9e-08
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 57 9e-08
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 57 1e-07
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 57 1e-07
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 57 1e-07
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 57 1e-07
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 57 1e-07
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 57 1e-07
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 57 1e-07
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 57 1e-07
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 57 1e-07
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 57 1e-07
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 57 1e-07
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 57 1e-07
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 56 1e-07
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 56 1e-07
AJ001054-1|CAA04504.1| 148|Homo sapiens NrCAM protein protein. 56 1e-07
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 56 1e-07
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 56 2e-07
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 56 2e-07
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 56 2e-07
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 56 3e-07
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 55 3e-07
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 55 3e-07
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 55 5e-07
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 55 5e-07
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 55 5e-07
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 54 6e-07
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 54 6e-07
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 54 8e-07
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 54 8e-07
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 54 8e-07
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 54 8e-07
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 54 8e-07
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 54 8e-07
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 54 1e-06
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 54 1e-06
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 54 1e-06
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 54 1e-06
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 54 1e-06
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 53 2e-06
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 53 2e-06
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 53 2e-06
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 53 2e-06
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 53 2e-06
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 52 2e-06
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 52 2e-06
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 52 2e-06
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 52 2e-06
S76476-1|AAB33112.1| 612|Homo sapiens trkC protein. 52 2e-06
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 52 2e-06
BT007291-1|AAP35955.1| 612|Homo sapiens neurotrophic tyrosine k... 52 2e-06
BC013693-1|AAH13693.1| 612|Homo sapiens neurotrophic tyrosine k... 52 2e-06
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 52 2e-06
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 52 2e-06
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 52 2e-06
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 52 3e-06
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 52 3e-06
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 52 3e-06
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 52 3e-06
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 52 4e-06
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 52 4e-06
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 51 6e-06
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 51 6e-06
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 50 1e-05
BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein. 50 1e-05
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 50 1e-05
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 50 1e-05
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 50 1e-05
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 50 2e-05
X16356-1|CAA34405.1| 373|Homo sapiens TM3-CEA protein protein. 50 2e-05
X16354-1|CAA34404.1| 526|Homo sapiens TM1-CEA preprotein protein. 50 2e-05
S71326-1|AAB31183.1| 464|Homo sapiens BGPc protein. 50 2e-05
M72238-1|AAA58394.1| 417|Homo sapiens biliary glycoprotein a pr... 50 2e-05
J03858-1|AAA51826.1| 526|Homo sapiens BGP protein. 50 2e-05
D90311-1|BAA14341.1| 417|Homo sapiens biliary glycoprotein prot... 50 2e-05
DQ989182-1|ABI75349.1| 526|Homo sapiens carcinoembryonic antige... 50 2e-05
BC024164-1|AAH24164.1| 493|Homo sapiens CEACAM1 protein protein. 50 2e-05
BC014473-1|AAH14473.1| 468|Homo sapiens CEACAM1 protein protein. 50 2e-05
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 50 2e-05
AL513328-3|CAI17351.1| 116|Homo sapiens muscle, skeletal, recep... 50 2e-05
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 50 2e-05
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 50 2e-05
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 50 2e-05
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 50 2e-05
AC004785-5|AAC18437.1| 417|Homo sapiens BGPg_HUMAN protein. 50 2e-05
AC004785-4|AAC18436.1| 464|Homo sapiens BGPc_HUMAN protein. 50 2e-05
AC004785-3|AAC18434.1| 526|Homo sapiens BGP1_HUMAN protein. 50 2e-05
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 49 2e-05
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 49 2e-05
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 49 2e-05
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 49 3e-05
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 48 4e-05
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 48 4e-05
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 48 4e-05
M76741-1|AAA57141.1| 226|Homo sapiens biliary glycoprotein prot... 48 5e-05
AK023854-1|BAB14704.1| 442|Homo sapiens .117). protein. 48 7e-05
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 47 9e-05
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 47 9e-05
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 47 9e-05
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 47 9e-05
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 47 9e-05
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 47 9e-05
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 47 9e-05
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 47 9e-05
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 47 9e-05
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 47 9e-05
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 47 9e-05
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 47 9e-05
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 47 1e-04
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 47 1e-04
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 47 1e-04
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 47 1e-04
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 47 1e-04
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 47 1e-04
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 46 2e-04
X69301-1|CAA49159.1| 976|Homo sapiens mast/stem cell growth fa... 46 2e-04
X06182-1|CAA29548.1| 976|Homo sapiens protein ( Human c-kit pro... 46 2e-04
U63834-2|AAC50969.1| 972|Homo sapiens KIT protein protein. 46 2e-04
U63834-1|AAC50968.1| 976|Homo sapiens KIT protein protein. 46 2e-04
BC071593-1|AAH71593.1| 976|Homo sapiens KIT protein protein. 46 2e-04
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 46 2e-04
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 46 3e-04
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 46 3e-04
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 46 3e-04
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 46 3e-04
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 46 3e-04
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 46 3e-04
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 46 3e-04
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 45 4e-04
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 45 4e-04
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 45 4e-04
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 45 4e-04
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 45 4e-04
AK023273-1|BAB14500.1| 431|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 45 4e-04
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 45 4e-04
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 45 5e-04
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 45 5e-04
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 45 5e-04
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 44 6e-04
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 44 6e-04
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 44 6e-04
AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion mo... 44 6e-04
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 44 9e-04
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 44 9e-04
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 44 9e-04
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 44 9e-04
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 44 9e-04
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 44 9e-04
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 44 9e-04
AK074556-1|BAC11057.1| 789|Homo sapiens protein ( Homo sapiens ... 44 9e-04
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 44 0.001
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 44 0.001
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 44 0.001
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 44 0.001
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 44 0.001
AY358153-1|AAQ88520.1| 262|Homo sapiens AWKS9372 protein. 44 0.001
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 44 0.001
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 44 0.001
AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing g... 44 0.001
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 44 0.001
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 44 0.001
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 44 0.001
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 44 0.001
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 44 0.001
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 43 0.001
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 43 0.001
BC114334-1|AAI14335.2| 280|Homo sapiens NRG2 protein protein. 43 0.001
BC114333-1|AAI14334.2| 280|Homo sapiens NRG2 protein protein. 43 0.001
BC103984-1|AAI03985.2| 280|Homo sapiens NRG2 protein protein. 43 0.001
BC103983-1|AAI03984.2| 280|Homo sapiens NRG2 protein protein. 43 0.001
BC013955-1|AAH13955.2| 365|Homo sapiens FGFRL1 protein protein. 43 0.001
AK172838-1|BAD18803.1| 218|Homo sapiens protein ( Homo sapiens ... 43 0.001
AF119162-4|AAF28849.1| 844|Homo sapiens neuregulin 2 isoform 2 ... 43 0.001
AF119162-3|AAF28851.1| 852|Homo sapiens neuregulin 2 isoform 4 ... 43 0.001
AF119162-2|AAF28848.1| 850|Homo sapiens neuregulin 2 isoform 1 ... 43 0.001
AF119162-1|AAF28850.1| 858|Homo sapiens neuregulin 2 isoform 3 ... 43 0.001
AF119158-1|AAF28852.1| 426|Homo sapiens neuregulin 2 isoform 5 ... 43 0.001
AF119157-1|AAF28853.1| 422|Homo sapiens neuregulin 2 isoform 6 ... 43 0.001
AB005060-1|BAA23417.1| 850|Homo sapiens NTAK protein. 43 0.001
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 43 0.002
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 43 0.002
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 43 0.002
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 43 0.002
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 43 0.002
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 43 0.002
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 43 0.002
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 43 0.002
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 43 0.002
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 43 0.002
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 43 0.002
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 43 0.002
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 43 0.002
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 43 0.002
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 43 0.002
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 43 0.002
BC100788-1|AAI00789.1| 467|Homo sapiens C9orf94 protein protein. 43 0.002
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 43 0.002
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 43 0.002
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 43 0.002
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 43 0.002
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 43 0.002
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 43 0.002
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 43 0.002
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 43 0.002
AL158150-1|CAM14351.1| 275|Homo sapiens chromosome 9 open readi... 43 0.002
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 43 0.002
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 43 0.002
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 43 0.002
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 43 0.002
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 43 0.002
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 43 0.002
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 43 0.002
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 43 0.002
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 42 0.003
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 42 0.003
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 42 0.003
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 42 0.003
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 42 0.003
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 42 0.003
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 42 0.003
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 42 0.003
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 42 0.003
AL590103-6|CAI12129.1| 188|Homo sapiens heparan sulfate proteog... 42 0.003
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 42 0.003
AK092602-1|BAC03925.1| 262|Homo sapiens protein ( Homo sapiens ... 42 0.003
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 42 0.003
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 42 0.003
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 42 0.003
X68264-1|CAA48332.1| 646|Homo sapiens melanoma associated glyco... 42 0.003
M29277-1|AAA20824.1| 646|Homo sapiens MUC18 glycoprotein protein. 42 0.003
M28882-1|AAA20922.1| 646|Homo sapiens MUC18 glycoprotein protein. 42 0.003
U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein. 42 0.005
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 42 0.005
CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein. 42 0.005
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 42 0.005
BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein. 42 0.005
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 42 0.005
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 42 0.005
AL391822-1|CAI14656.1| 302|Homo sapiens neurofascin homolog (ch... 42 0.005
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 42 0.005
AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens ... 42 0.005
AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens ... 42 0.005
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 156 bits (379), Expect = 1e-37
Identities = 98/344 (28%), Positives = 159/344 (46%), Gaps = 16/344 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + G+R + NG+L+I PF + +H Y C + G I S+++
Sbjct: 69 WYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIR-SQDV 127
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
H+ A L P+ V V D+ + GN V +C++P I+ W D ++++ GS++
Sbjct: 128 HIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSW-EKDTVSLVS--GSRF 184
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G+LYI V D + C R + TG N+ + + V++P P +
Sbjct: 185 LITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNS--ARLFVSDPANSA-PSILDG 241
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
R+ GQ V LPC P P YRW ++ P+E L R + GLL I+
Sbjct: 242 FEHRKAMAGQRVELPCKALGHPEPDYRWLKDN----MPLE---LSGRFQKTVTGLL-IEN 293
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R D+G +VC ++N G+ V L V +P+ P ++S S ++L C V G
Sbjct: 294 IRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTED 353
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCF 345
+ + W NG L P + + I + L + + K D G YQCF
Sbjct: 354 QELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCF 397
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 550 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 607
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 608 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 664
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 665 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 713
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 714 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 773
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 774 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 833
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 834 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 888
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 418 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 473
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 474 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 532
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 533 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 586
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 492 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 545
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 546 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 598
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 599 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 648
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 649 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 708
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 709 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 767
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 768 VEEDSGYYLCKVSNDVGADVSKSMYL 793
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
S +I EP R+ + +D+ LPC P P +W + + TP
Sbjct: 1284 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG--TP-SL 1340
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
T+ R + G I+ V+ ED+G + C NN GS+ + L V P
Sbjct: 1341 VTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1390
Score = 41.5 bits (93), Expect = 0.005
Identities = 78/347 (22%), Positives = 139/347 (40%), Gaps = 42/347 (12%)
Query: 21 LKNGSLEILPFTAELYRHDVHATV----YRCRMRSS-VGYIAMSKNIHVYAALSSPWEVH 75
L +GS ++ T LY DV YRC R G S + ++ + +
Sbjct: 178 LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPS 237
Query: 76 VPDEY----VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLY 131
+ D + +AG V L C H WL D N+ L ++ + G L
Sbjct: 238 ILDGFEHRKAMAGQRVELPCKALGHPEP---DYRWLKD---NMPLELSGRFQKTVTG-LL 290
Query: 132 ISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG 191
I + SD + ++C V + R ++ + V +P + ++ R + VG
Sbjct: 291 IENIRPSDSGS-YVCEVSN-----RYGTAKVIGRLYVKQPL-----KATISPRKVKSSVG 339
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
V L C+V W+ + E L P + + + E L+ V+ D G +
Sbjct: 340 SQVSLSCSVTGTEDQELSWY-RNGEILNPGKNVRI---TGINHENLIMDHMVK-SDGGAY 394
Query: 252 VCWLNNTVGSESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW-L 308
C++ S + +++ + P + E + S P ++L C V G P+ + W L
Sbjct: 395 QCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLMCNVKGTPLPTITWTL 453
Query: 309 HNGRTLEP-NERIE--ILEDG---LRLHIKNTHKDDQGIYQCFASNA 349
+ L+ + RI I +G L+I ++ D G+Y+C A+N+
Sbjct: 454 DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 500
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL--HNG--RTLEP 316
SE + + P + T + + DI L CK G P V W+ NG +
Sbjct: 1284 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTI 1343
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R I +G + I+ +D G Y C A+N
Sbjct: 1344 DGRRSIFSNGSFI-IRTVKAEDSGYYSCIANN 1374
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 155 bits (377), Expect = 2e-37
Identities = 98/344 (28%), Positives = 159/344 (46%), Gaps = 16/344 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + G+R + NG+L+I PF + +H Y C + G I S+++
Sbjct: 58 WYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIR-SQDV 116
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
H+ A L P+ V V D+ + GN V +C++P I+ W D ++++ GS++
Sbjct: 117 HIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSW-EKDTVSLVS--GSRF 173
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G+LYI V D + C R + TG N+ + + V++P P +
Sbjct: 174 LITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNS--ARLFVSDPANSA-PSILDG 230
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
R+ GQ V LPC P P YRW ++ P+E L R + GLL I+
Sbjct: 231 FDHRKAMAGQRVELPCKALGHPEPDYRWLKDN----MPLE---LSGRFQKTVTGLL-IEN 282
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R D+G +VC ++N G+ V L V +P+ P ++S S ++L C V G
Sbjct: 283 IRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTED 342
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCF 345
+ + W NG L P + + I + L + + K D G YQCF
Sbjct: 343 QELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCF 386
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 539 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 597 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 653
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 654 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 702
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 703 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 762
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 763 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 822
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 823 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 877
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 462
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 521
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 522 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 481 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 534
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 535 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 587
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 588 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 637
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 638 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 697
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 698 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 756
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 757 VEEDSGYYLCKVSNDVGADVSKSMYL 782
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
S +I EP R+ + +D+ LPC P P +W + + TP
Sbjct: 1273 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG--TP-SL 1329
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
T+ R + G I+ V+ ED+G + C NN GS+ + L V P
Sbjct: 1330 VTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1379
Score = 41.5 bits (93), Expect = 0.005
Identities = 78/347 (22%), Positives = 139/347 (40%), Gaps = 42/347 (12%)
Query: 21 LKNGSLEILPFTAELYRHDVHATV----YRCRMRSS-VGYIAMSKNIHVYAALSSPWEVH 75
L +GS ++ T LY DV YRC R G S + ++ + +
Sbjct: 167 LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPS 226
Query: 76 VPDEY----VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLY 131
+ D + +AG V L C H WL D N+ L ++ + G L
Sbjct: 227 ILDGFDHRKAMAGQRVELPCKALGHPEP---DYRWLKD---NMPLELSGRFQKTVTG-LL 279
Query: 132 ISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG 191
I + SD + ++C V + R ++ + V +P + ++ R + VG
Sbjct: 280 IENIRPSDSGS-YVCEVSN-----RYGTAKVIGRLYVKQPL-----KATISPRKVKSSVG 328
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
V L C+V W+ + E L P + + + E L+ V+ D G +
Sbjct: 329 SQVSLSCSVTGTEDQELSWY-RNGEILNPGKNVRI---TGINHENLIMDHMVK-SDGGAY 383
Query: 252 VCWLNNTVGSESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW-L 308
C++ S + +++ + P + E + S P ++L C V G P+ + W L
Sbjct: 384 QCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLMCNVKGTPLPTITWTL 442
Query: 309 HNGRTLEP-NERIE--ILEDG---LRLHIKNTHKDDQGIYQCFASNA 349
+ L+ + RI I +G L+I ++ D G+Y+C A+N+
Sbjct: 443 DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL--HNG--RTLEP 316
SE + + P + T + + DI L CK G P V W+ NG +
Sbjct: 1273 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTI 1332
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R I +G + I+ +D G Y C A+N
Sbjct: 1333 DGRRSIFSNGSFI-IRTVKAEDSGYYSCIANN 1363
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 155 bits (377), Expect = 2e-37
Identities = 98/344 (28%), Positives = 159/344 (46%), Gaps = 16/344 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + G+R + NG+L+I PF + +H Y C + G I S+++
Sbjct: 58 WYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIR-SQDV 116
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
H+ A L P+ V V D+ + GN V +C++P I+ W D ++++ GS++
Sbjct: 117 HIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSW-EKDTVSLVS--GSRF 173
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G+LYI V D + C R + TG N+ + + V++P P +
Sbjct: 174 LITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNS--ARLFVSDPANSA-PSILDG 230
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
R+ GQ V LPC P P YRW ++ P+E L R + GLL I+
Sbjct: 231 FDHRKAMAGQRVELPCKALGHPEPDYRWLKDN----MPLE---LSGRFQKTVTGLL-IEN 282
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R D+G +VC ++N G+ V L V +P+ P ++S S ++L C V G
Sbjct: 283 IRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTED 342
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCF 345
+ + W NG L P + + I + L + + K D G YQCF
Sbjct: 343 QELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCF 386
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 539 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 597 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 653
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 654 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 702
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 703 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 762
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 763 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 822
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 823 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 877
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 462
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 521
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 522 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 481 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 534
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 535 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 587
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 588 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 637
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 638 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 697
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 698 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 756
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 757 VEEDSGYYLCKVSNDVGADVSKSMYL 782
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
S +I EP R+ + +D+ LPC P P +W + + TP
Sbjct: 1273 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG--TP-SL 1329
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
T+ R + G I+ V+ ED+G + C NN GS+ + L V P
Sbjct: 1330 VTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1379
Score = 41.5 bits (93), Expect = 0.005
Identities = 78/347 (22%), Positives = 139/347 (40%), Gaps = 42/347 (12%)
Query: 21 LKNGSLEILPFTAELYRHDVHATV----YRCRMRSS-VGYIAMSKNIHVYAALSSPWEVH 75
L +GS ++ T LY DV YRC R G S + ++ + +
Sbjct: 167 LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPS 226
Query: 76 VPDEY----VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLY 131
+ D + +AG V L C H WL D N+ L ++ + G L
Sbjct: 227 ILDGFDHRKAMAGQRVELPCKALGHPEP---DYRWLKD---NMPLELSGRFQKTVTG-LL 279
Query: 132 ISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG 191
I + SD + ++C V + R ++ + V +P + ++ R + VG
Sbjct: 280 IENIRPSDSGS-YVCEVSN-----RYGTAKVIGRLYVKQPL-----KATISPRKVKSSVG 328
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
V L C+V W+ + E L P + + + E L+ V+ D G +
Sbjct: 329 SQVSLSCSVTGTEDQELSWY-RNGEILNPGKNVRI---TGINHENLIMDHMVK-SDGGAY 383
Query: 252 VCWLNNTVGSESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW-L 308
C++ S + +++ + P + E + S P ++L C V G P+ + W L
Sbjct: 384 QCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLMCNVKGTPLPTITWTL 442
Query: 309 HNGRTLEP-NERIE--ILEDG---LRLHIKNTHKDDQGIYQCFASNA 349
+ L+ + RI I +G L+I ++ D G+Y+C A+N+
Sbjct: 443 DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL--HNG--RTLEP 316
SE + + P + T + + DI L CK G P V W+ NG +
Sbjct: 1273 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTI 1332
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R I +G + I+ +D G Y C A+N
Sbjct: 1333 DGRRSIFSNGSFI-IRTVKAEDSGYYSCIANN 1363
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 155 bits (377), Expect = 2e-37
Identities = 98/344 (28%), Positives = 159/344 (46%), Gaps = 16/344 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + G+R + NG+L+I PF + +H Y C + G I S+++
Sbjct: 44 WYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIR-SQDV 102
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
H+ A L P+ V V D+ + GN V +C++P I+ W D ++++ GS++
Sbjct: 103 HIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSW-EKDTVSLVS--GSRF 159
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G+LYI V D + C R + TG N+ + + V++P P +
Sbjct: 160 LITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNS--ARLFVSDPANSA-PSILDG 216
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
R+ GQ V LPC P P YRW ++ P+E L R + GLL I+
Sbjct: 217 FDHRKAMAGQRVELPCKALGHPEPDYRWLKDN----MPLE---LSGRFQKTVTGLL-IEN 268
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R D+G +VC ++N G+ V L V +P+ P ++S S ++L C V G
Sbjct: 269 IRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTED 328
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCF 345
+ + W NG L P + + I + L + + K D G YQCF
Sbjct: 329 QELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCF 372
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 525 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 582
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 583 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 639
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 640 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 688
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 689 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 748
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 749 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 808
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 809 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 863
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 393 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 448
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 449 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 507
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 508 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 561
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 467 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 520
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 521 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 573
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 574 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 623
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 624 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 683
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 684 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 742
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 743 VEEDSGYYLCKVSNDVGADVSKSMYL 768
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
S +I EP R+ + +D+ LPC P P +W + + TP
Sbjct: 1259 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG--TP-SL 1315
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
T+ R + G I+ V+ ED+G + C NN GS+ + L V P
Sbjct: 1316 VTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1365
Score = 41.5 bits (93), Expect = 0.005
Identities = 78/347 (22%), Positives = 139/347 (40%), Gaps = 42/347 (12%)
Query: 21 LKNGSLEILPFTAELYRHDVHATV----YRCRMRSS-VGYIAMSKNIHVYAALSSPWEVH 75
L +GS ++ T LY DV YRC R G S + ++ + +
Sbjct: 153 LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPS 212
Query: 76 VPDEY----VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLY 131
+ D + +AG V L C H WL D N+ L ++ + G L
Sbjct: 213 ILDGFDHRKAMAGQRVELPCKALGHPEP---DYRWLKD---NMPLELSGRFQKTVTG-LL 265
Query: 132 ISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG 191
I + SD + ++C V + R ++ + V +P + ++ R + VG
Sbjct: 266 IENIRPSDSGS-YVCEVSN-----RYGTAKVIGRLYVKQPL-----KATISPRKVKSSVG 314
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
V L C+V W+ + E L P + + + E L+ V+ D G +
Sbjct: 315 SQVSLSCSVTGTEDQELSWY-RNGEILNPGKNVRI---TGINHENLIMDHMVK-SDGGAY 369
Query: 252 VCWLNNTVGSESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW-L 308
C++ S + +++ + P + E + S P ++L C V G P+ + W L
Sbjct: 370 QCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLMCNVKGTPLPTITWTL 428
Query: 309 HNGRTLEP-NERIE--ILEDG---LRLHIKNTHKDDQGIYQCFASNA 349
+ L+ + RI I +G L+I ++ D G+Y+C A+N+
Sbjct: 429 DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 475
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL--HNG--RTLEP 316
SE + + P + T + + DI L CK G P V W+ NG +
Sbjct: 1259 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTI 1318
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R I +G + I+ +D G Y C A+N
Sbjct: 1319 DGRRSIFSNGSFI-IRTVKAEDSGYYSCIANN 1349
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell
adhesion molecule 2 protein.
Length = 2113
Score = 154 bits (374), Expect = 4e-37
Identities = 98/354 (27%), Positives = 160/354 (45%), Gaps = 20/354 (5%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + +R + NG+L++ PF+ + +H Y C ++ G I S NI
Sbjct: 119 WYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIR-SPNI 177
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVL--HYLGS 120
V A P+ V V D+ + GN V +C++P + +S W D ++++ H
Sbjct: 178 RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSW-EKDTVSIIPEHRFFI 236
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
YH G LYIS V D + + C + K +G N + + VT+P + P +
Sbjct: 237 TYH----GGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAESI-PTIL 289
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
S+ + G V LPC +P+P RW + P+ + W + R+ L+I
Sbjct: 290 DGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGR----PLPADSRWTK-RITG---LTI 341
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
+R ED+G ++C + NT GS L+V +P+ V P+ L++ S + L C + G
Sbjct: 342 SDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGS 401
Query: 301 PIELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P + W N + P+E I I L I + K G YQCFA+ A
Sbjct: 402 PEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 455
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 8/172 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ L CA P PT W + + T + + D
Sbjct: 468 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRT--NQYTMSDGT 525
Query: 237 LLSIQKV---RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL 293
+S V + D G + C N VGS + V P S+R + + D +
Sbjct: 526 TISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR-DTLI 584
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+C+V G+P + W + L N R + E+G L + + K D+G Y C
Sbjct: 585 NCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG-TLKLTDVQKGMDEGEYLC 635
Score = 45.6 bits (103), Expect = 3e-04
Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFE----HHEQLTPIEETTLWKRA 230
V PR V+ ++ G+ L C+V +P P W + +Q P+ T R
Sbjct: 748 VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG---RI 804
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKS 289
++L L I+ V ED G ++C +N VG++ S L V P + + P +
Sbjct: 805 QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGH 864
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDG----LRLHIKNTHKDDQGI 341
L+C G ++ W ++P+ I ++G L +K + D
Sbjct: 865 AKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVF 924
Query: 342 YQCFASNARDQAYGM 356
+ C A N+ + G+
Sbjct: 925 FSCHAINSYGEDRGL 939
Score = 44.8 bits (101), Expect = 5e-04
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
+DVRLPC P P +W + + P+ ++ + G L ++ V+ ED+G +
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---SMDGHRLIHTNGTLLLRAVKAEDSGYY 1421
Query: 252 VCWLNNTVGSESVHFTLIVTEP 273
C NT G +++ L+V P
Sbjct: 1422 TCTATNTGGFDTIIVNLLVQVP 1443
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule DSCAML1 protein.
Length = 2053
Score = 152 bits (369), Expect = 2e-36
Identities = 95/352 (26%), Positives = 160/352 (45%), Gaps = 16/352 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + +R + NG+L++ PF+ + +H Y C ++ G I S NI
Sbjct: 59 WYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIR-SPNI 117
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
V A P+ V V D+ + GN V +C++P + +S W D ++++ +++
Sbjct: 118 RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSW-EKDTVSIIPE--NRF 174
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G LYIS V D + + C + K +G N + + VT+P + P +
Sbjct: 175 FITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAESI-PTILDG 231
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S+ + G V LPC +P+P RW + P+ + W + R+ L+I
Sbjct: 232 FHSQEVWAGHTVELPCTASGYPIPAIRWLKDGR----PLPADSRWTK-RITG---LTISD 283
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R ED+G ++C + NT GS L+V +P+ V P+ L++ S + L C + G P
Sbjct: 284 LRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPE 343
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ W N + P+E I I L I + K G YQCFA+ A
Sbjct: 344 FTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 395
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 8/172 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ L CA P PT W + + T + + D
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRT--NQYTMSDGT 465
Query: 237 LLSIQKV---RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL 293
+S V + D G + C N VGS + V P S+R + + D +
Sbjct: 466 TISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR-DTLI 524
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+C+V G+P + W + L N R + E+G L + + K D+G Y C
Sbjct: 525 NCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG-TLKLTDVQKGMDEGEYLC 575
Score = 45.6 bits (103), Expect = 3e-04
Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFE----HHEQLTPIEETTLWKRA 230
V PR V+ ++ G+ L C+V +P P W + +Q P+ T R
Sbjct: 688 VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG---RI 744
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKS 289
++L L I+ V ED G ++C +N VG++ S L V P + + P +
Sbjct: 745 QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGH 804
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDG----LRLHIKNTHKDDQGI 341
L+C G ++ W ++P+ I ++G L +K + D
Sbjct: 805 AKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVF 864
Query: 342 YQCFASNARDQAYGM 356
+ C A N+ + G+
Sbjct: 865 FSCHAINSYGEDRGL 879
Score = 44.8 bits (101), Expect = 5e-04
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
+DVRLPC P P +W + + P+ ++ + G L ++ V+ ED+G +
Sbjct: 1305 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---SMDGHRLIHTNGTLLLRAVKAEDSGYY 1361
Query: 252 VCWLNNTVGSESVHFTLIVTEP 273
C NT G +++ L+V P
Sbjct: 1362 TCTATNTGGFDTIIVNLLVQVP 1383
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 152 bits (369), Expect = 2e-36
Identities = 95/352 (26%), Positives = 160/352 (45%), Gaps = 16/352 (4%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + +R + NG+L++ PF+ + +H Y C ++ G I S NI
Sbjct: 98 WYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIR-SPNI 156
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
V A P+ V V D+ + GN V +C++P + +S W D ++++ +++
Sbjct: 157 RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSW-EKDTVSIIPE--NRF 213
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
G LYIS V D + + C + K +G N + + VT+P + P +
Sbjct: 214 FITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAESI-PTILDG 270
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S+ + G V LPC +P+P RW + P+ + W + R+ L+I
Sbjct: 271 FHSQEVWAGHTVELPCTASGYPIPAIRWLKDGR----PLPADSRWTK-RITG---LTISD 322
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+R ED+G ++C + NT GS L+V +P+ V P+ L++ S + L C + G P
Sbjct: 323 LRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPE 382
Query: 303 ELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ W N + P+E I I L I + K G YQCFA+ A
Sbjct: 383 FTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 434
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 8/172 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ L CA P PT W + + T + + D
Sbjct: 447 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRT--NQYTMSDGT 504
Query: 237 LLSIQKV---RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL 293
+S V + D G + C N VGS + V P S+R + + D +
Sbjct: 505 TISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR-DTLI 563
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+C+V G+P + W + L N R + E+G L + + K D+G Y C
Sbjct: 564 NCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG-TLKLTDVQKGMDEGEYLC 614
Score = 45.6 bits (103), Expect = 3e-04
Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFE----HHEQLTPIEETTLWKRA 230
V PR V+ ++ G+ L C+V +P P W + +Q P+ T R
Sbjct: 727 VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG---RI 783
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKS 289
++L L I+ V ED G ++C +N VG++ S L V P + + P +
Sbjct: 784 QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGH 843
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDG----LRLHIKNTHKDDQGI 341
L+C G ++ W ++P+ I ++G L +K + D
Sbjct: 844 AKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVF 903
Query: 342 YQCFASNARDQAYGM 356
+ C A N+ + G+
Sbjct: 904 FSCHAINSYGEDRGL 918
Score = 44.8 bits (101), Expect = 5e-04
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
+DVRLPC P P +W + + P+ ++ + G L ++ V+ ED+G +
Sbjct: 1344 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---SMDGHRLIHTNGTLLLRAVKAEDSGYY 1400
Query: 252 VCWLNNTVGSESVHFTLIVTEP 273
C NT G +++ L+V P
Sbjct: 1401 TCTATNTGGFDTIIVNLLVQVP 1422
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1a protein.
Length = 2053
Score = 151 bits (367), Expect = 3e-36
Identities = 98/354 (27%), Positives = 160/354 (45%), Gaps = 20/354 (5%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + +R + NG+L++ PF+ + +H Y C ++ G I S NI
Sbjct: 59 WYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIR-SPNI 117
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVL--HYLGS 120
V A P+ V V D+ + GN V +C++P + +S W D ++++ H
Sbjct: 118 RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPFLGQEYVSVVSW-EKDTVSIIPEHRFFI 176
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
YH G LYIS V D + + C + K +G N + + VT+P + P +
Sbjct: 177 TYH----GGLYISDVQKEDALSTYRCITKHKYSGETRQSNG--ARLSVTDPAESI-PTIL 229
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
S+ + G V LPC +P+P RW + P+ + W + R+ L+I
Sbjct: 230 DGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGR----PLPADSRWTK-RITG---LTI 281
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
+R ED+G ++C + NT GS L+V +P+ V P+ L++ S + L C + G
Sbjct: 282 SDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGS 341
Query: 301 PIELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P + W N + P+E I I L I + K G YQCFA+ A
Sbjct: 342 PEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 395
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 8/172 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ L CA P PT W + + T + + D
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRT--NQYTMSDGT 465
Query: 237 LLSIQKV---RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL 293
+S V + D G + C N VGS + V P S+R + + D +
Sbjct: 466 TISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR-DTLI 524
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+C+V G+P + W + L N R + E+G L + + K D+G Y C
Sbjct: 525 NCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG-TLKLTDVQKGMDEGEYLC 575
Score = 45.6 bits (103), Expect = 3e-04
Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFE----HHEQLTPIEETTLWKRA 230
V PR V+ ++ G+ L C+V +P P W + +Q P+ T R
Sbjct: 688 VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG---RI 744
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKS 289
++L L I+ V ED G ++C +N VG++ S L V P + + P +
Sbjct: 745 QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGH 804
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDG----LRLHIKNTHKDDQGI 341
L+C G ++ W ++P+ I ++G L +K + D
Sbjct: 805 AKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVF 864
Query: 342 YQCFASNARDQAYGM 356
+ C A N+ + G+
Sbjct: 865 FSCHAINSYGEDRGL 879
Score = 44.8 bits (101), Expect = 5e-04
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
+DVRLPC P P +W + + P+ ++ + G L ++ V+ ED+G +
Sbjct: 1305 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---SMDGHRLIHTNGTLLLRAVKAEDSGYY 1361
Query: 252 VCWLNNTVGSESVHFTLIVTEP 273
C NT G +++ L+V P
Sbjct: 1362 TCTATNTGGFDTIIVNLLVQVP 1383
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 97.5 bits (232), Expect = 7e-20
Identities = 67/227 (29%), Positives = 103/227 (45%), Gaps = 12/227 (5%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S++ G+LYI V D + C R + TG N+ + + V++P P +
Sbjct: 1 SRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNS--ARLFVSDPANSA-PSI 57
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
R+ GQ V LPC P P YRW ++ P+E L R + GLL
Sbjct: 58 LDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDN----MPLE---LSGRFQKTVTGLL- 109
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
I+ +R D+G +VC ++N G+ V L V +P+ P ++S S ++L C V G
Sbjct: 110 IENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTG 169
Query: 300 HPIELVYWLHNGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCF 345
+ + W NG L P + + I + L + + K D G YQCF
Sbjct: 170 TEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCF 216
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 369 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 426
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 427 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 483
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 484 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 532
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 533 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 592
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 593 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 652
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 653 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 707
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 237 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 292
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 293 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 351
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 352 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 311 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 364
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 365 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 417
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 418 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 467
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 468 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 527
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 528 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 586
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 587 VEEDSGYYLCKVSNDVGADVSKSMYL 612
Score = 39.9 bits (89), Expect = 0.014
Identities = 63/277 (22%), Positives = 114/277 (41%), Gaps = 33/277 (11%)
Query: 82 IAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRH 141
+AG V L C H WL D N+ L ++ + G L I + SD
Sbjct: 67 MAGQRVELPCKALGHPEP---DYRWLKD---NMPLELSGRFQKTVTG-LLIENIRPSDSG 119
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
+ ++C V + R ++ + V +P + ++ R + VG V L C+V
Sbjct: 120 S-YVCEVSN-----RYGTAKVIGRLYVKQPL-----KATISPRKVKSSVGSQVSLSCSVT 168
Query: 202 AWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS 261
W+ + E L P + + + E L+ V+ D G + C++ S
Sbjct: 169 GTEDQELSWY-RNGEILNPGKNVRI---TGINHENLIMDHMVK-SDGGAYQCFVRKDKLS 223
Query: 262 ESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLEP-N 317
+ +++ + P + E + S P ++L C V G P+ + W L + L+ +
Sbjct: 224 AQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLMCNVKGTPLPTITWTLDDDPILKGGS 282
Query: 318 ERIE--ILEDG---LRLHIKNTHKDDQGIYQCFASNA 349
RI I +G L+I ++ D G+Y+C A+N+
Sbjct: 283 HRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 319
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 95.5 bits (227), Expect = 3e-19
Identities = 86/317 (27%), Positives = 136/317 (42%), Gaps = 18/317 (5%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y+C ++VG I + +A L + V G VVL C PPH + I S
Sbjct: 171 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYS- 229
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
W+ ++ + + ++ + G+LYIS V TSD + ++C V++ +T R
Sbjct: 230 -WVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNARVLSPPTPL 287
Query: 165 HVIVTEPKGGVKPRVSVE-QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+ G +P++ V + G V++ C PVPT W +
Sbjct: 288 TLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGY------- 340
Query: 224 TTLWKRARLL-DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTKPE 281
+ +ARL + +L I V+ +DAG + C N+ G S L + T P V K
Sbjct: 341 --IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE-KLN 397
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
+ S + +CK G P WL NG L P R+E++ L +H N ++ D G+
Sbjct: 398 DTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH--NVNQSDAGM 455
Query: 342 YQCFASNARDQAYGMSE 358
YQC A N Y +E
Sbjct: 456 YQCLAENKYGAIYASAE 472
Score = 51.2 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 17/197 (8%)
Query: 177 PRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P ++ Q + I V Q+V + C P PT W + + E KR +L
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW----KKGDRAVREN---KRIAILP 532
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
+G L I + D G++VC N GS + +L V EP + P+ I L+
Sbjct: 533 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 592
Query: 295 CK-VNGHPIELV-YWLHNGRTLEPNER------IEILEDGLRLHIKNTHKDDQGIYQCFA 346
CK ++ +++ YW G+ ++ E I L I+N G Y C
Sbjct: 593 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 652
Query: 347 SNARDQAYGMSEYLFDG 363
D +E L G
Sbjct: 653 QTTADSVSDEAELLVRG 669
Score = 46.8 bits (106), Expect = 1e-04
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 14/171 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C V PVP+YRW T I+ + + R L+D + +D+G + C
Sbjct: 119 VALNCEVRGNPVPSYRWL----RNGTEIDLESDY-RYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 254 WLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY-WLH 309
NTVG S S RT+ V + + L C H E++Y W+
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAV-SVREGQGVVLMCSPPPHSPEIIYSWVF 232
Query: 310 N---GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMS 357
N E + R E G L+I D G Y C N A +S
Sbjct: 233 NEFPSFVAEDSRRFISQETG-NLYISKVQTSDVGSYICLVKNTVTNARVLS 282
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 273 PISVRTKPEVL--RSKPKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLR 328
P+ V+ +++ + +AL+C+V G+P+ WL NG LE + R ++ DG
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-DGTF 157
Query: 329 LHIKNTHKDDQGIYQCFASN 348
+ + D G YQC A+N
Sbjct: 158 IISNPSEAKDSGHYQCLATN 177
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 95.5 bits (227), Expect = 3e-19
Identities = 86/317 (27%), Positives = 136/317 (42%), Gaps = 18/317 (5%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y+C ++VG I + +A L + V G VVL C PPH + I S
Sbjct: 97 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYS- 155
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
W+ ++ + + ++ + G+LYIS V TSD + ++C V++ +T R
Sbjct: 156 -WVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNARVLSPPTPL 213
Query: 165 HVIVTEPKGGVKPRVSVE-QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+ G +P++ V + G V++ C PVPT W +
Sbjct: 214 TLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGY------- 266
Query: 224 TTLWKRARLL-DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTKPE 281
+ +ARL + +L I V+ +DAG + C N+ G S L + T P V K
Sbjct: 267 --IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE-KLN 323
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
+ S + +CK G P WL NG L P R+E++ L +H N ++ D G+
Sbjct: 324 DTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH--NVNQSDAGM 381
Query: 342 YQCFASNARDQAYGMSE 358
YQC A N Y +E
Sbjct: 382 YQCLAENKYGAIYASAE 398
Score = 51.2 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 17/197 (8%)
Query: 177 PRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P ++ Q + I V Q+V + C P PT W + + E KR +L
Sbjct: 406 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW----KKGDRAVREN---KRIAILP 458
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
+G L I + D G++VC N GS + +L V EP + P+ I L+
Sbjct: 459 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 518
Query: 295 CK-VNGHPIELV-YWLHNGRTLEPNER------IEILEDGLRLHIKNTHKDDQGIYQCFA 346
CK ++ +++ YW G+ ++ E I L I+N G Y C
Sbjct: 519 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 578
Query: 347 SNARDQAYGMSEYLFDG 363
D +E L G
Sbjct: 579 QTTADSVSDEAELLVRG 595
Score = 46.8 bits (106), Expect = 1e-04
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 14/171 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C V PVP+YRW T I+ + + R L+D + +D+G + C
Sbjct: 45 VALNCEVRGNPVPSYRWL----RNGTEIDLESDY-RYSLIDGTFIISNPSEAKDSGHYQC 99
Query: 254 WLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY-WLH 309
NTVG S S RT+ V + + L C H E++Y W+
Sbjct: 100 LATNTVGSILSREATLQFAYLGNFSGRTRSAV-SVREGQGVVLMCSPPPHSPEIIYSWVF 158
Query: 310 N---GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMS 357
N E + R E G L+I D G Y C N A +S
Sbjct: 159 NEFPSFVAEDSRRFISQETG-NLYISKVQTSDVGSYICLVKNTVTNARVLS 208
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 273 PISVRTKPEVL--RSKPKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLR 328
P+ V+ +++ + +AL+C+V G+P+ WL NG LE + R ++ DG
Sbjct: 25 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-DGTF 83
Query: 329 LHIKNTHKDDQGIYQCFASN 348
+ + D G YQC A+N
Sbjct: 84 IISNPSEAKDSGHYQCLATN 103
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 95.5 bits (227), Expect = 3e-19
Identities = 86/317 (27%), Positives = 136/317 (42%), Gaps = 18/317 (5%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y+C ++VG I + +A L + V G VVL C PPH + I S
Sbjct: 171 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYS- 229
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
W+ ++ + + ++ + G+LYIS V TSD + ++C V++ +T R
Sbjct: 230 -WVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNARVLSPPTPL 287
Query: 165 HVIVTEPKGGVKPRVSVE-QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+ G +P++ V + G V++ C PVPT W +
Sbjct: 288 TLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGY------- 340
Query: 224 TTLWKRARLL-DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTKPE 281
+ +ARL + +L I V+ +DAG + C N+ G S L + T P V K
Sbjct: 341 --IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE-KLN 397
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
+ S + +CK G P WL NG L P R+E++ L +H N ++ D G+
Sbjct: 398 DTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIH--NVNQSDAGM 455
Query: 342 YQCFASNARDQAYGMSE 358
YQC A N Y +E
Sbjct: 456 YQCLAENKYGAIYASAE 472
Score = 51.2 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 17/197 (8%)
Query: 177 PRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P ++ Q + I V Q+V + C P PT W + + E KR +L
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW----KKGDRAVREN---KRIAILP 532
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
+G L I + D G++VC N GS + +L V EP + P+ I L+
Sbjct: 533 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 592
Query: 295 CK-VNGHPIELV-YWLHNGRTLEPNER------IEILEDGLRLHIKNTHKDDQGIYQCFA 346
CK ++ +++ YW G+ ++ E I L I+N G Y C
Sbjct: 593 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 652
Query: 347 SNARDQAYGMSEYLFDG 363
D +E L G
Sbjct: 653 QTTADSVSDEAELLVRG 669
Score = 46.8 bits (106), Expect = 1e-04
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 14/171 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C V PVP+YRW T I+ + + R L+D + +D+G + C
Sbjct: 119 VALNCEVRGNPVPSYRWL----RNGTEIDLESDY-RYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 254 WLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY-WLH 309
NTVG S S RT+ V + + L C H E++Y W+
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAV-SVREGQGVVLMCSPPPHSPEIIYSWVF 232
Query: 310 N---GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMS 357
N E + R E G L+I D G Y C N A +S
Sbjct: 233 NEFPSFVAEDSRRFISQETG-NLYISKVQTSDVGSYICLVKNTVTNARVLS 282
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 273 PISVRTKPEVL--RSKPKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLR 328
P+ V+ +++ + +AL+C+V G+P+ WL NG LE + R ++ DG
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI-DGTF 157
Query: 329 LHIKNTHKDDQGIYQCFASN 348
+ + D G YQC A+N
Sbjct: 158 IISNPSEAKDSGHYQCLATN 177
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 93.9 bits (223), Expect = 8e-19
Identities = 92/333 (27%), Positives = 143/333 (42%), Gaps = 21/333 (6%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMR-SSVGYIAMSKNIHVYAALSSPWEVHV 76
RQ+L +GSL I + Y+C S+G I +S+ + A +
Sbjct: 101 RQLLPDGSLFISNVVHSKHNKPDEG-YYQCVATVESLGTI-ISRTAKLIVAGLPRFTSQP 158
Query: 77 PDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
V AGN +L C V AD + W + + L L + +L G L IS +
Sbjct: 159 EPSSVYAGNGAILNCEVN---ADLVPFVRW--EQNRQPL-LLDDRVIKLPSGMLVISNAT 212
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV-GQDVR 195
D + C V +G + V ++ +P+ + V ++Q S +RV GQDV
Sbjct: 213 EGDG-GLYRCVVE---SGGPPKYSDEVELKVLPDPEV-ISDLVFLKQPSPLVRVIGQDVV 267
Query: 196 LPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWL 255
LPC P PT +W ++ E L +T +R LL G L I V +DAG + C
Sbjct: 268 LPCVASGLPTPTIKWM-KNEEAL----DTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE 315
+N + L V +P + + DI +C+V G P V W+ NG +
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382
Query: 316 PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P++ +I+++ L + K D+G YQC A N
Sbjct: 383 PSDYFKIVKEH-NLQVLGLVKSDEGFYQCIAEN 414
Score = 66.1 bits (154), Expect = 2e-10
Identities = 73/291 (25%), Positives = 120/291 (41%), Gaps = 27/291 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDD-INVLHYLGSKYHRLDDGSLYISAVS 136
D + G++V+L C + +I EW D +N++ + L DGSL+IS V
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKI---EWKKDGTFLNLVS--DDRRQLLPDGSLFISNVV 115
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
S +HN+ + + + + T++S G PR + + + G L
Sbjct: 116 HS-KHNKPDEGYYQCVATVES-LGTIISRTAKLIVAG--LPRFTSQPEPSSVYAGNGAIL 171
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C V+A VP RW E + Q +++ R L G+L I D G + C +
Sbjct: 172 NCEVNADLVPFVRW--EQNRQPLLLDD-----RVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 257 N---TVGSESVHFTLI----VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ S+ V ++ V + +P L D+ L C +G P + W+
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 310 NGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
N L E +ER+ +L G L I + +DD G Y C A N + +E
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAE 334
Score = 33.9 bits (74), Expect = 0.91
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D+ C V P PT +W ++ + + P + + K L GL+ + D G +
Sbjct: 357 DIVFECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLV------KSDEGFYQ 409
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
C N VG+ LI+ E T P L S P+ +A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHAPATTGP--LPSAPRDVVA 447
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 93.1 bits (221), Expect = 1e-18
Identities = 92/333 (27%), Positives = 143/333 (42%), Gaps = 21/333 (6%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMR-SSVGYIAMSKNIHVYAALSSPWEVHV 76
RQ+L +GSL I + Y+C S+G I +S+ + A +
Sbjct: 101 RQLLPDGSLFISNVVHSKHNKPDEG-YYQCVATVESLGTI-ISRTAKLIVAGLPRFTSQP 158
Query: 77 PDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
V AGN +L C V AD + W + + L L + +L G L IS +
Sbjct: 159 EPSSVYAGNNAILNCEVN---ADLVPFVRW--EQNRQPL-LLDDRVIKLPSGMLVISNAT 212
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV-GQDVR 195
D + C V +G + V ++ +P+ + V ++Q S +RV GQDV
Sbjct: 213 EGDG-GLYRCVVE---SGGPPKYSDEVELKVLPDPEV-ISDLVFLKQPSPLVRVIGQDVV 267
Query: 196 LPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWL 255
LPC P PT +W ++ E L +T +R LL G L I V +DAG + C
Sbjct: 268 LPCVASGLPTPTIKWM-KNEEAL----DTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE 315
+N + L V +P + + DI +C+V G P V W+ NG +
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382
Query: 316 PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P++ +I+++ L + K D+G YQC A N
Sbjct: 383 PSDYFKIVKEH-NLQVLGLVKSDEGFYQCIAEN 414
Score = 66.9 bits (156), Expect = 1e-10
Identities = 73/291 (25%), Positives = 121/291 (41%), Gaps = 27/291 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDD-INVLHYLGSKYHRLDDGSLYISAVS 136
D + G++V+L C + +I EW D +N++ + L DGSL+IS V
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKI---EWKKDGTFLNLVS--DDRRQLLPDGSLFISNVV 115
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
S +HN+ + + + + T++S G PR + + + G + L
Sbjct: 116 HS-KHNKPDEGYYQCVATVES-LGTIISRTAKLIVAG--LPRFTSQPEPSSVYAGNNAIL 171
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C V+A VP RW E + Q +++ R L G+L I D G + C +
Sbjct: 172 NCEVNADLVPFVRW--EQNRQPLLLDD-----RVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 257 N---TVGSESVHFTLI----VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ S+ V ++ V + +P L D+ L C +G P + W+
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 310 NGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
N L E +ER+ +L G L I + +DD G Y C A N + +E
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAE 334
Score = 33.9 bits (74), Expect = 0.91
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D+ C V P PT +W ++ + + P + + K L GL+ + D G +
Sbjct: 357 DIVFECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLV------KSDEGFYQ 409
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
C N VG+ LI+ E T P L S P+ +A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHAPATTGP--LPSAPRDVVA 447
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 93.1 bits (221), Expect = 1e-18
Identities = 92/333 (27%), Positives = 143/333 (42%), Gaps = 21/333 (6%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMR-SSVGYIAMSKNIHVYAALSSPWEVHV 76
RQ+L +GSL I + Y+C S+G I +S+ + A +
Sbjct: 101 RQLLPDGSLFISNVVHSKHNKPDEG-YYQCVATVESLGTI-ISRTAKLIVAGLPRFTSQP 158
Query: 77 PDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
V AGN +L C V AD + W + + L L + +L G L IS +
Sbjct: 159 EPSSVYAGNNAILNCEVN---ADLVPFVRW--EQNRQPL-LLDDRVIKLPSGMLVISNAT 212
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV-GQDVR 195
D + C V +G + V ++ +P+ + V ++Q S +RV GQDV
Sbjct: 213 EGDG-GLYRCVVE---SGGPPKYSDEVELKVLPDPEV-ISDLVFLKQPSPLVRVIGQDVV 267
Query: 196 LPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWL 255
LPC P PT +W ++ E L +T +R LL G L I V +DAG + C
Sbjct: 268 LPCVASGLPTPTIKWM-KNEEAL----DTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE 315
+N + L V +P + + DI +C+V G P V W+ NG +
Sbjct: 323 DNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVI 382
Query: 316 PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P++ +I+++ L + K D+G YQC A N
Sbjct: 383 PSDYFKIVKEH-NLQVLGLVKSDEGFYQCIAEN 414
Score = 66.9 bits (156), Expect = 1e-10
Identities = 73/291 (25%), Positives = 121/291 (41%), Gaps = 27/291 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDD-INVLHYLGSKYHRLDDGSLYISAVS 136
D + G++V+L C + +I EW D +N++ + L DGSL+IS V
Sbjct: 61 DTLSVRGSSVILNCSAYSEPSPKI---EWKKDGTFLNLVS--DDRRQLLPDGSLFISNVV 115
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
S +HN+ + + + + T++S G PR + + + G + L
Sbjct: 116 HS-KHNKPDEGYYQCVATVES-LGTIISRTAKLIVAG--LPRFTSQPEPSSVYAGNNAIL 171
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C V+A VP RW E + Q +++ R L G+L I D G + C +
Sbjct: 172 NCEVNADLVPFVRW--EQNRQPLLLDD-----RVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 257 N---TVGSESVHFTLI----VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ S+ V ++ V + +P L D+ L C +G P + W+
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 310 NGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
N L E +ER+ +L G L I + +DD G Y C A N + +E
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAE 334
Score = 33.9 bits (74), Expect = 0.91
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D+ C V P PT +W ++ + + P + + K L GL+ + D G +
Sbjct: 357 DIVFECEVTGKPTPTVKWV-KNGDMVIPSDYFKIVKEHNLQVLGLV------KSDEGFYQ 409
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
C N VG+ LI+ E T P L S P+ +A
Sbjct: 410 CIAENDVGNAQAGAQLIILEHAPATTGP--LPSAPRDVVA 447
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 85.8 bits (203), Expect = 2e-16
Identities = 84/319 (26%), Positives = 134/319 (42%), Gaps = 19/319 (5%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRIS 102
+Y+C + +G I +S+ + A +E + G VVL C PPH D
Sbjct: 97 MYQCLATNLLGTI-LSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDL-- 153
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W +D+ + ++ + G+LYI+ V SD N + C + +K R+
Sbjct: 154 SYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGN-YTCFITNK-EAQRSVQGPP 211
Query: 163 VSHVIVTEP-KGGVKPRVSVEQRSRRIRVGQD--VRLPCAVHAWPVPTYRWFFEHHEQLT 219
V T+ G +P++ V + I+ +D V+L C PVP W +
Sbjct: 212 TPLVQRTDGVMGEYEPKIEV-RFPETIQAAKDSSVKLECFALGNPVPDISW---RRLDGS 267
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK 279
P+ + ++ + +L I ++ED G + C +N G LI P K
Sbjct: 268 PLPGKVKYSKS----QAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQK 323
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ ++ +CK +G P WL NG L P ERI+I E+G L I + D
Sbjct: 324 IQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI-ENG-TLIITMLNVSDS 381
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 382 GVYQCAAENKYQIIYANAE 400
Score = 59.3 bits (137), Expect = 2e-08
Identities = 65/256 (25%), Positives = 109/256 (42%), Gaps = 29/256 (11%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S ++RLD GSL I++ T + C + + G + + + + + + V
Sbjct: 74 SYHYRLDGGSLAINSPHTDQDIGMYQC-LATNLLGTILSRKAKLQFAYIEDFETKTRSTV 132
Query: 180 SVEQRSRRIRVGQDVRLPCAV--HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL 237
SV R GQ V L C H + +Y W F + ++E +R + G
Sbjct: 133 SV-------REGQGVVLLCGPPPHFGDL-SYAWTFNDNPLY--VQEDN--RRFVSQETGN 180
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHF--TLIVT---------EP-ISVRTKPEVLRS 285
L I KV D G + C++ N SV T +V EP I VR PE +++
Sbjct: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRF-PETIQA 239
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
S + L+C G+P+ + W + P +++ + L I N ++D+G Y+C
Sbjct: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPLPG-KVKYSKSQAILEIPNFQQEDEGFYECI 298
Query: 346 ASNARDQAYGMSEYLF 361
ASN R + + +F
Sbjct: 299 ASNLRGRNLAKGQLIF 314
Score = 58.8 bits (136), Expect = 3e-08
Identities = 59/247 (23%), Positives = 104/247 (42%), Gaps = 22/247 (8%)
Query: 124 RLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQ 183
++++G+L I+ ++ SD + C +K I V+ + P P V++
Sbjct: 365 QIENGTLIITMLNVSDS-GVYQCAAENKYQIIYANAEL---RVLASAPDFSKSP---VKK 417
Query: 184 RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKV 243
+S ++VG D+ + C +A+P W E KR LL++G L I +
Sbjct: 418 KSF-VQVGGDIVIGCKPNAFPRAAISW-------KRGTETLRQSKRIFLLEDGSLKIYNI 469
Query: 244 RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-I 302
R DAG + C N G+ +LIV E + P + I L C+V+ P I
Sbjct: 470 TRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSI 529
Query: 303 ELVY-WLHNGRTLEPNERIEILE----DGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
E+V+ W NG ++ + + E + + L I+N G Y C + +
Sbjct: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
Query: 357 SEYLFDG 363
++ + G
Sbjct: 590 ADIIVRG 596
Score = 47.2 bits (107), Expect = 9e-05
Identities = 48/168 (28%), Positives = 65/168 (38%), Gaps = 16/168 (9%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR-EDAGRF 251
+V L CA + +P P YRW + T I+ T + LD G L+I +D G +
Sbjct: 45 EVILNCAANGYPSPHYRW----KQNGTDIDFTMSYHYR--LDGGSLAINSPHTDQDIGMY 98
Query: 252 VCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY-W 307
C N +G S E +T+ V + + L C H +L Y W
Sbjct: 99 QCLATNLLGTILSRKAKLQFAYIEDFETKTRSTV-SVREGQGVVLLCGPPPHFGDLSYAW 157
Query: 308 LHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
N L E N R E G L+I D G Y CF +N Q
Sbjct: 158 TFNDNPLYVQEDNRRFVSQETG-NLYIAKVEPSDVGNYTCFITNKEAQ 204
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 288 KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQCFA 346
KS++ L+C NG+P W NG ++ DG L I + H D D G+YQC A
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
Query: 347 SN 348
+N
Sbjct: 103 TN 104
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 85.8 bits (203), Expect = 2e-16
Identities = 84/319 (26%), Positives = 134/319 (42%), Gaps = 19/319 (5%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRIS 102
+Y+C + +G I +S+ + A +E + G VVL C PPH D
Sbjct: 97 MYQCLATNLLGTI-LSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDL-- 153
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W +D+ + ++ + G+LYI+ V SD N + C + +K R+
Sbjct: 154 SYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGN-YTCFITNK-EAQRSVQGPP 211
Query: 163 VSHVIVTEP-KGGVKPRVSVEQRSRRIRVGQD--VRLPCAVHAWPVPTYRWFFEHHEQLT 219
V T+ G +P++ V + I+ +D V+L C PVP W +
Sbjct: 212 TPLVQRTDGVMGEYEPKIEV-RFPETIQAAKDSSVKLECFALGNPVPDISW---RRLDGS 267
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK 279
P+ + ++ + +L I ++ED G + C +N G LI P K
Sbjct: 268 PLPGKVKYSKS----QAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQK 323
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ ++ +CK +G P WL NG L P ERI+I E+G L I + D
Sbjct: 324 IQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI-ENG-TLIITMLNVSDS 381
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 382 GVYQCAAENKYQIIYANAE 400
Score = 59.3 bits (137), Expect = 2e-08
Identities = 65/256 (25%), Positives = 109/256 (42%), Gaps = 29/256 (11%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S ++RLD GSL I++ T + C + + G + + + + + + V
Sbjct: 74 SYHYRLDGGSLAINSPHTDQDIGMYQC-LATNLLGTILSRKAKLQFAYIEDFETKTRSTV 132
Query: 180 SVEQRSRRIRVGQDVRLPCAV--HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL 237
SV R GQ V L C H + +Y W F + ++E +R + G
Sbjct: 133 SV-------REGQGVVLLCGPPPHFGDL-SYAWTFNDNPLY--VQEDN--RRFVSQETGN 180
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHF--TLIVT---------EP-ISVRTKPEVLRS 285
L I KV D G + C++ N SV T +V EP I VR PE +++
Sbjct: 181 LYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRF-PETIQA 239
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
S + L+C G+P+ + W + P +++ + L I N ++D+G Y+C
Sbjct: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPLPG-KVKYSKSQAILEIPNFQQEDEGFYECI 298
Query: 346 ASNARDQAYGMSEYLF 361
ASN R + + +F
Sbjct: 299 ASNLRGRNLAKGQLIF 314
Score = 58.8 bits (136), Expect = 3e-08
Identities = 59/247 (23%), Positives = 104/247 (42%), Gaps = 22/247 (8%)
Query: 124 RLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQ 183
++++G+L I+ ++ SD + C +K I V+ + P P V++
Sbjct: 365 QIENGTLIITMLNVSDS-GVYQCAAENKYQIIYANAEL---RVLASAPDFSKSP---VKK 417
Query: 184 RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKV 243
+S ++VG D+ + C +A+P W E KR LL++G L I +
Sbjct: 418 KSF-VQVGGDIVIGCKPNAFPRAAISW-------KRGTETLRQSKRIFLLEDGSLKIYNI 469
Query: 244 RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-I 302
R DAG + C N G+ +LIV E + P + I L C+V+ P I
Sbjct: 470 TRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSI 529
Query: 303 ELVY-WLHNGRTLEPNERIEILE----DGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
E+V+ W NG ++ + + E + + L I+N G Y C + +
Sbjct: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
Query: 357 SEYLFDG 363
++ + G
Sbjct: 590 ADIIVRG 596
Score = 47.2 bits (107), Expect = 9e-05
Identities = 48/168 (28%), Positives = 65/168 (38%), Gaps = 16/168 (9%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR-EDAGRF 251
+V L CA + +P P YRW + T I+ T + LD G L+I +D G +
Sbjct: 45 EVILNCAANGYPSPHYRW----KQNGTDIDFTMSYHYR--LDGGSLAINSPHTDQDIGMY 98
Query: 252 VCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY-W 307
C N +G S E +T+ V + + L C H +L Y W
Sbjct: 99 QCLATNLLGTILSRKAKLQFAYIEDFETKTRSTV-SVREGQGVVLLCGPPPHFGDLSYAW 157
Query: 308 LHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
N L E N R E G L+I D G Y CF +N Q
Sbjct: 158 TFNDNPLYVQEDNRRFVSQETG-NLYIAKVEPSDVGNYTCFITNKEAQ 204
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 288 KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQCFA 346
KS++ L+C NG+P W NG ++ DG L I + H D D G+YQC A
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLA 102
Query: 347 SN 348
+N
Sbjct: 103 TN 104
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 85.4 bits (202), Expect = 3e-16
Identities = 90/341 (26%), Positives = 143/341 (41%), Gaps = 25/341 (7%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVP 77
+Q L NGSL I + H +Y+C +S+ V A++ P
Sbjct: 89 KQQLSNGSLLIQNILHSRH-HKPDEGLYQCEASLGDSGSIISRTAKV--AVAGPLRFLSQ 145
Query: 78 DEYVIA--GNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISA 134
E V A G+ V+L+C V + + + W N D+ + S+ L G+L IS
Sbjct: 146 TESVTAFMGDTVLLKCEV---IGEPMPTIHWQKNQQDLTPIPG-DSRVVVLPSGALQISR 201
Query: 135 VSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV--GQ 192
+ D + C R+ + RT V I+++P G+ ++ QR + G+
Sbjct: 202 LQPGDI-GIYRCSARNPASS-RTGNEAEVR--ILSDP--GLHRQLYFLQRPSNVVAIEGK 255
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D L C V +P P++ W E++ + K+ LL L I V +D+G +
Sbjct: 256 DAVLECCVSGYPPPSFTWL--RGEEVIQLRS----KKYSLLGGSNLLISNVTDDDSGMYT 309
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C + + S L V P P L + DI +C V+G P+ V W+ NG
Sbjct: 310 CVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGD 369
Query: 313 TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ P++ +I+ G L I K D+G YQC A N A
Sbjct: 370 VVIPSDYFQIV-GGSNLRILGVVKSDEGFYQCVAENEAGNA 409
Score = 60.9 bits (141), Expect = 7e-09
Identities = 69/291 (23%), Positives = 119/291 (40%), Gaps = 24/291 (8%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADR-ISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
D + G V+L C +DR + +W D I++ + + +L +GSL I +
Sbjct: 48 DAVTMRGGNVLLDCSAE---SDRGVPVIKW-KKDGIHLALGMDERKQQLSNGSLLIQNIL 103
Query: 137 TSDRH--NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDV 194
S H + L + + G ++ + + V V P R + S +G V
Sbjct: 104 HSRHHKPDEGLYQCEASL-GDSGSIISRTAKVAVAGPL-----RFLSQTESVTAFMGDTV 157
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C V P+PT W ++ + LTPI + R +L G L I +++ D G + C
Sbjct: 158 LLKCEVIGEPMPTIHWQ-KNQQDLTPIPGDS---RVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 255 LNNTVGSESVHFT--LIVTEP-----ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
N S + + I+++P + +P + + D L+C V+G+P W
Sbjct: 214 ARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW 273
Query: 308 LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
L ++ + L G L I N DD G+Y C + + +E
Sbjct: 274 LRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAE 324
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 85.4 bits (202), Expect = 3e-16
Identities = 90/341 (26%), Positives = 143/341 (41%), Gaps = 25/341 (7%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVP 77
+Q L NGSL I + H +Y+C +S+ V A++ P
Sbjct: 89 KQQLSNGSLLIQNILHSRH-HKPDEGLYQCEASLGDSGSIISRTAKV--AVAGPLRFLSQ 145
Query: 78 DEYVIA--GNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISA 134
E V A G+ V+L+C V + + + W N D+ + S+ L G+L IS
Sbjct: 146 TESVTAFMGDTVLLKCEV---IGEPMPTIHWQKNQQDLTPIPG-DSRVVVLPSGALQISR 201
Query: 135 VSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV--GQ 192
+ D + C R+ + RT V I+++P G+ ++ QR + G+
Sbjct: 202 LQPGDI-GIYRCSARNPASS-RTGNEAEVR--ILSDP--GLHRQLYFLQRPSNVVAIEGK 255
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D L C V +P P++ W E++ + K+ LL L I V +D+G +
Sbjct: 256 DAVLECCVSGYPPPSFTWL--RGEEVIQLRS----KKYSLLGGSNLLISNVTDDDSGMYT 309
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C + + S L V P P L + DI +C V+G P+ V W+ NG
Sbjct: 310 CVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGD 369
Query: 313 TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ P++ +I+ G L I K D+G YQC A N A
Sbjct: 370 VVIPSDYFQIV-GGSNLRILGVVKSDEGFYQCVAENEAGNA 409
Score = 60.9 bits (141), Expect = 7e-09
Identities = 69/291 (23%), Positives = 119/291 (40%), Gaps = 24/291 (8%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADR-ISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
D + G V+L C +DR + +W D I++ + + +L +GSL I +
Sbjct: 48 DAVTMRGGNVLLDCSAE---SDRGVPVIKW-KKDGIHLALGMDERKQQLSNGSLLIQNIL 103
Query: 137 TSDRH--NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDV 194
S H + L + + G ++ + + V V P R + S +G V
Sbjct: 104 HSRHHKPDEGLYQCEASL-GDSGSIISRTAKVAVAGPL-----RFLSQTESVTAFMGDTV 157
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C V P+PT W ++ + LTPI + R +L G L I +++ D G + C
Sbjct: 158 LLKCEVIGEPMPTIHWQ-KNQQDLTPIPGDS---RVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 255 LNNTVGSESVHFT--LIVTEP-----ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
N S + + I+++P + +P + + D L+C V+G+P W
Sbjct: 214 ARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW 273
Query: 308 LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
L ++ + L G L I N DD G+Y C + + +E
Sbjct: 274 LRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAE 324
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 85.4 bits (202), Expect = 3e-16
Identities = 88/359 (24%), Positives = 139/359 (38%), Gaps = 36/359 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDINV 114
+ N++++ + + VI GN + L C + PP+ + + L D V
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRV 2245
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
G + L IS SD + C V + G L ++ T G
Sbjct: 2246 RILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNSG 2296
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + R G+ + L C V P PT W + H P+ + K +LD
Sbjct: 2297 SHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEILD 2343
Query: 235 EG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKSD 290
EG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 EGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNS 2403
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ + W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 VSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2462
Score = 82.6 bits (195), Expect = 2e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 1309 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 77.4 bits (182), Expect = 7e-14
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2264 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2323
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2324 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2375
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2376 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSITWFKDGW---- 2425
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2426 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2482
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2543 PHTGRYTCLASS 2554
Score = 77.4 bits (182), Expect = 7e-14
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3124
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3125 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3184
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3185 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 73.7 bits (173), Expect = 9e-13
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 2978 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 3030
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3031 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3090
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3091 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4202
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4203 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4258
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4259 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4307
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 4308 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIE 4361
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4420
Query: 346 ASN 348
A+N
Sbjct: 4421 ATN 4423
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3945 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3995
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3996 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4050
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4051 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4099
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4100 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4212
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4213 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3669
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3730 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3788
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 1060
Score = 69.3 bits (162), Expect = 2e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 1026 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 1084
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 1085 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 1135
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 1195
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2490 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2542
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2602
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2650
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3532 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3584
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3585 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3644
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3834 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3892
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3893 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3941
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3942 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3996
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3997 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4056
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4057 MCVAQNPAGTALG 4069
Score = 66.9 bits (156), Expect = 1e-10
Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2839
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P ++ PE + ++C +G
Sbjct: 2840 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGS 2899
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2900 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2420 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2471
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2472 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2524
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2581
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2582 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2632
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2751
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2752 ---GEDELDFDVNI 2762
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 65.3 bits (152), Expect = 3e-10
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAG 249
G + L C P P W ++ +P+ ++ R R+L G L I + DA
Sbjct: 2211 GNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILSGGRQLQISIAEKSDAA 2265
Query: 250 RFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+ C +N G+ + L V T S E++ ++ KS I+L+C+V G P V
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS-ISLECEVQGIPPPTV 2324
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA---RDQAYGMS 357
W+ +G L + +EIL++G L +KN H D G Y C A N D+ Y +S
Sbjct: 2325 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 3149 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 3203
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3263
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3264 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3323
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3324 PAGEEDRIFNLNVYV 3338
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4363 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4415
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4416 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4475
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4476 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4513
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3490 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3550 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3603
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3258 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3312
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 3372
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2920 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1958
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1959 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 2017
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2018 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 2071
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 2072 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 2131
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2132 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4128 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4176
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4177 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4230
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4231 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4291 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4333
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 347 SN 348
+N
Sbjct: 3879 TN 3880
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3356 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2685 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2738
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 4326 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4379
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4380 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4434
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4435 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4478
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4479 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 85.4 bits (202), Expect = 3e-16
Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L+DG+L + A T + ++C + A T + + +K + V
Sbjct: 388 LEDGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNV 441
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 442 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGRILKLFRA 492
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P + D+AL+C+V G P
Sbjct: 493 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTP 552
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 553 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 601
Score = 81.8 bits (193), Expect = 3e-15
Identities = 79/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 162 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 216
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 217 -GMYLC-VAINIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 265
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 266 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 319
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 320 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 379
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILEDG L I + D G Y C A N
Sbjct: 380 GREPGISILEDGTLLVIASVTPYDNGEYICVAVN 413
Score = 77.4 bits (182), Expect = 7e-14
Identities = 54/195 (27%), Positives = 81/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 878 AANTAGDHKEEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 937
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 938 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 992
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + R L + + L G + I++
Sbjct: 993 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESA 1052
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1053 QISDAGIYKCVAINS 1067
Score = 68.1 bits (159), Expect = 5e-11
Identities = 54/230 (23%), Positives = 94/230 (40%), Gaps = 11/230 (4%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 97 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 155
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 156 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKET-QLISPFSP-----RHTFLPSGSM 206
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN 298
I + R D+G ++C N G+ + L V P ++ P+ L+ + + + C
Sbjct: 207 KITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQ 266
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P+ ++ W G T+ + + L I D GIY C A+N
Sbjct: 267 GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 316
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 538 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 591
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+C+ G P+ +
Sbjct: 592 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAIT 651
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 652 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 698
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 636 IKLECETRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 688
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+CK G+P ++ WL
Sbjct: 689 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLK 748
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I I G +L I + + D+G Y C A++
Sbjct: 749 DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATS 787
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/163 (23%), Positives = 72/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ + + L+ T R +++D I+ + D
Sbjct: 1003 VLVSNPVQLECKAAGNPVPVITWY-KDNRLLSGSTSMTFLNRGQIID-----IESAQISD 1056
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1057 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 1116
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + + D G Y C A NA
Sbjct: 1117 LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 1159
Score = 56.4 bits (130), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 768 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 827
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 828 HVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 880
Score = 55.6 bits (128), Expect = 3e-07
Identities = 73/347 (21%), Positives = 130/347 (37%), Gaps = 29/347 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 931 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 984
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D+
Sbjct: 985 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKDN------------ 1029
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
RL GS ++ ++ + ++ D A+N+ + + + V P +S
Sbjct: 1030 -RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGS 1088
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQ 241
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 1089 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILALT 1142
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
+ D GR+ C N G + L V P ++ + + + + L C+ + P
Sbjct: 1143 SAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIP 1202
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 1203 PPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 1249
Score = 50.8 bits (116), Expect = 7e-06
Identities = 28/120 (23%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
+G L I++V+ +D G + C +N G+ + +++V +++ ++L + + L
Sbjct: 13 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLP 72
Query: 295 CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
CK +G+P V W G + + + DG L++ + ++ G Y C A+N A
Sbjct: 73 CKASGNPKPSVIWSKKGELISTSSAKFSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 131
Score = 36.7 bits (81), Expect = 0.13
Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 6/86 (6%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
V P + E+++ + + Q V L C A P PT W + H L + R+
Sbjct: 1173 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS---- 1228
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVG 260
+L I+ + +D GR+ C N G
Sbjct: 1229 --VLKIEDAQVQDTGRYTCEATNVAG 1252
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 85.0 bits (201), Expect = 4e-16
Identities = 85/343 (24%), Positives = 136/343 (39%), Gaps = 35/343 (10%)
Query: 7 DNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYA 66
D PV+ G I +G L + + A Y C ++VG + +H+
Sbjct: 971 DGQPVSGAEGKFTIQPSGELLVKNLEGQ------DAGTYTCTAENAVG--RARRRVHLTI 1022
Query: 67 ALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD 126
+ + D + G+ + LRC RI T +ND + D
Sbjct: 1023 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT--VNDRPVT------EGVSEQD 1074
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
GS A + + ++C +++ RT VS V V E P + E S
Sbjct: 1075 GGSTLQRAAVSREDSGTYVCWAENRVG--RTQA---VSFVHVKEA-----PVLQGEAFSY 1124
Query: 187 RIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+ VG ++L C V PVP W + P+ + L + L G L+I + R
Sbjct: 1125 LVEPVGGSIQLDCVVRGDPVPDIHWIKDG----LPLRGSHLRHQ---LQNGSLTIHRTER 1177
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
+DAGR+ C N +G L++ + +P+ + + D+AL C+ G P +
Sbjct: 1178 DDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTI 1237
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL G+ L + R+ L DG L ++N D G Y C A N
Sbjct: 1238 EWLQAGQPLRASRRLRTLPDG-SLWLENVETGDAGTYDCVAHN 1279
Score = 66.1 bits (154), Expect = 2e-10
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 12/157 (7%)
Query: 196 LPCAVHAWPVPTYRWFFEHHEQLTPIEE--TTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
L C+V A P P W H + + E+ T +R R L +Q + D+G + C
Sbjct: 517 LECSVEAEPAPKITW---HRDGIVLQEDAHTQFPERGRFLQ-----LQALSTADSGDYSC 568
Query: 254 WLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRT 313
N GS SV F + + ++R+ P + L C+ +G P LV W +
Sbjct: 569 TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVP 628
Query: 314 LEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+P + R EIL +G L I+ D G Y C ASN+
Sbjct: 629 LDPRSPRFEILPEG-SLRIQPVLAQDAGHYLCLASNS 664
Score = 66.1 bits (154), Expect = 2e-10
Identities = 56/199 (28%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 156 RTAVNTLVSHVIVT-EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEH 214
R + HV +T + VKP SV R ++V LPC P PT W E
Sbjct: 827 RNSAGVAHKHVFLTVQASPVVKPLPSVV----RAVAEEEVLLPCEASGIPRPTITWQKEG 882
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
T + ++L G L I EDAG ++C N+ GS L+V P
Sbjct: 883 LNVATGVS-------TQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPP 935
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
+ L + S L CK G P + W +G+ + E ++ L +KN
Sbjct: 936 VIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNL 995
Query: 335 HKDDQGIYQCFASNARDQA 353
D G Y C A NA +A
Sbjct: 996 EGQDAGTYTCTAENAVGRA 1014
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 9/179 (5%)
Query: 175 VKPRV--SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ S R + GQ+VRL C P P W + +P+ +
Sbjct: 127 VAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDG----SPLGQDMGPHLRFY 182
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE---VLRSKPKS 289
LD G L ++ + DAG + C +N G ++ T+ V P +++ + L S+P
Sbjct: 183 LDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGE 242
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ + C V G P V WL +G L ++R + G L I D GI+ C A++
Sbjct: 243 LVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAAS 301
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 7/181 (3%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
V P ++ +Q + + V L C P PT W + QL R+
Sbjct: 752 VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWS-KAGAQLG-----ARGSGYRVSP 805
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
G L I + AGR+ C N+ G H L V V+ P V+R+ + ++ L
Sbjct: 806 SGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLP 865
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
C+ +G P + W G + ++L G +L I + +D G Y C A N+ A
Sbjct: 866 CEASGIPRPTITWQKEGLNVATGVSTQVLPGG-QLRIAHASPEDAGNYLCIAKNSAGSAM 924
Query: 355 G 355
G
Sbjct: 925 G 925
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 31/229 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI--AGNAVVLRCVVPPHCADRIS 102
Y C + VG +HV A E Y++ G ++ L CVV D +
Sbjct: 1092 YVCWAENRVGRTQAVSFVHVKEAPVLQGEAF---SYLVEPVGGSIQLDCVVR---GDPVP 1145
Query: 103 STEWLNDDDINVLHYLGSKY-HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
W+ D L GS H+L +GSL I D R+ C +++ G+ V
Sbjct: 1146 DIHWIKDG----LPLRGSHLRHQLQNGSLTIHRTERDDA-GRYQCLAENEM-GVAKKVVI 1199
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
LV P VE + +R G DV L C P PT W + P+
Sbjct: 1200 LVLQSA---------PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL----QAGQPL 1246
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ +R R L +G L ++ V DAG + C +N +GS + L+V
Sbjct: 1247 RAS---RRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT-KPEVLRSKPKSDIALDCK 296
L IQ+ + D G + C ++N G FTL V P + K E + S + L C
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 60
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
V+G P V WL + +E + ++ G RL + G Y C A N + +A
Sbjct: 61 VSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEA 117
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 12/163 (7%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G + L C V P PT W + P+E + + + G L + +++ AG
Sbjct: 52 GSPLVLTCDVSGVPAPTVTWLKDR----MPVESSAV--HGVVSRGGRLQLSRLQPAQAGT 105
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSK---PKSDIALDCKVNGHPIELVYW 307
+ C NT F + V +R+ V R ++ LDC+ +G P V W
Sbjct: 106 YTCVAENTQAEARKDFVVAVLVAPRIRSS-GVAREHHVLEGQEVRLDCEADGQPPPDVAW 164
Query: 308 LHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L +G L + + DG L +K D G Y C A N
Sbjct: 165 LKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHN 207
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/161 (23%), Positives = 63/161 (39%), Gaps = 10/161 (6%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G + L C P P W + + LT +E + R +L ++ V+ DAG
Sbjct: 421 GAPMELLCDAQGTPQPNITWH-KDGQALTRLENNSRATR-------VLRVENVQVRDAGL 472
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISV--RTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
+ C + G+ F + V P ++ P + + L+C V P + W
Sbjct: 473 YTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWH 532
Query: 309 HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+G L+ + + E G L ++ D G Y C A NA
Sbjct: 533 RDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA 573
Score = 47.6 bits (108), Expect = 7e-05
Identities = 58/221 (26%), Positives = 85/221 (38%), Gaps = 22/221 (9%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A +Y C S G I S + V A + +A +VL C V A +I
Sbjct: 470 AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKI 529
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
+ W D VL L + A+ST+D + + C R+ A
Sbjct: 530 T---WHRDGI--VLQEDAHTQFPERGRFLQLQALSTADSGD-YSCTARNAAGSTSVAFRV 583
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ H + T G P V+V V Q LPC P P W + P+
Sbjct: 584 EI-HTVPTIRSG--PPAVNVS-------VNQTALLPCQADGVPAPLVSW----RKDRVPL 629
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE 262
+ + R +L EG L IQ V +DAG ++C +N+ GS+
Sbjct: 630 DPRS--PRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSD 668
Score = 46.4 bits (105), Expect = 2e-04
Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 7/120 (5%)
Query: 233 LDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKS 289
L++G L ++ V D+G + C + G HF L V EP I +P L P +
Sbjct: 363 LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGA 422
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR-LHIKNTHKDDQGIYQCFASN 348
+ L C G P + W +G+ L R+E R L ++N D G+Y C A +
Sbjct: 423 PMELLCDAQGTPQPNITWHKDGQAL---TRLENNSRATRVLRVENVQVRDAGLYTCLAES 479
Score = 37.9 bits (84), Expect = 0.056
Identities = 38/170 (22%), Positives = 61/170 (35%), Gaps = 8/170 (4%)
Query: 189 RVGQDVR----LPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
R G+D+R LPC P P W+ + + +++ RLL L +
Sbjct: 669 RQGRDLRVLALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAY----RLLPSNALLLTAPG 724
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
+D+ +F C ++N VG + + V P ++ + + L C G P
Sbjct: 725 PQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPT 784
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
V W G L + L I G Y C A N+ A+
Sbjct: 785 VSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH 834
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 84.6 bits (200), Expect = 5e-16
Identities = 63/231 (27%), Positives = 113/231 (48%), Gaps = 23/231 (9%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L++G+L + A T + ++C + A T + + +K + V
Sbjct: 1317 LEEGTLLVIASVTPYDNGEYIC------VAVNEAGTTERKYNLKVHVPPVIKDKEQVSNV 1370
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKV 243
S + + Q L C V P P W+ + + Q+T E +T+ + ++ G +L + +
Sbjct: 1371 S--VLLNQLTNLFCEVEGTPSPIIMWY-KDNVQVT--ESSTI----QTVNNGKILKLFRA 1421
Query: 244 RREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTK-PEVLRSKPKSDIALDCKVNGHP 301
EDAGR+ C N G+ +F + ++ P + T P+ + D+AL+C+V G P
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVKGTP 1481
Query: 302 IELVYWLHNGRTL---EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++W +G+ L +PN +E+L+ G LH+KN ++D+G YQC SNA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPN--VELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Score = 81.0 bits (191), Expect = 6e-15
Identities = 78/274 (28%), Positives = 108/274 (39%), Gaps = 28/274 (10%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V+AG V L C V I+ W + + + ++ L GS+ I+ TSD
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIIT---WAKETQL--ISPFSPRHTFLPSGSMKITETRTSDS 1145
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+LC V I G T L HV P++ + +++VGQ V +PC
Sbjct: 1146 -GMYLC-VATNIAGNVTQAVKLNVHV---------PPKIQRGPKHLKVQVGQRVDIPCNA 1194
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P+P W L E +G LSI + DAG + C N G
Sbjct: 1195 QGTPLPVITWSKGGSTMLVDGEHHVS------NPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-----LDCKVNGHPIELVYWLHNGRTLE 315
++ TL V EP +V + + +A C G P + WLHNGR L
Sbjct: 1249 TDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELT 1308
Query: 316 PNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
E I ILE+G L I + D G Y C A N
Sbjct: 1309 GREPGISILEEGTLLVIASVTPYDNGEYICVAVN 1342
Score = 80.2 bits (189), Expect = 1e-14
Identities = 88/360 (24%), Positives = 137/360 (38%), Gaps = 37/360 (10%)
Query: 5 QSDNTPVASLSGLRQ---ILKNGSLEILPFTAELYRHDVHATV---YRCRMRSSVGYIAM 58
QSD P +L+ L+ +LK L I + L D Y C + G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 59 SK-NIHVYAALSSPWEVHVPDEYVIAGNAVVLRC----VVPPHCADRISSTEWLNDDDIN 113
N++++ + + VI GN + L C + PP+ + + L D
Sbjct: 2186 KNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGR 2245
Query: 114 VLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKG 173
V G + L IS SD + C V + G L ++ T
Sbjct: 2246 VRILSGGR-------QLQISIAEKSDAA-LYSC-VASNVAGTAKKEYNLQVYIRPTITNS 2296
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P + R G+ + L C V P PT W + H P+ + K +L
Sbjct: 2297 GSHPTEIIVTR------GKSISLECEVQGIPPPTVTWMKDGH----PLIKA---KGVEIL 2343
Query: 234 DEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV---RTKPEVLRSKPKS 289
DEG +L ++ + D GR+VC N G + L V P S+ PE + K+
Sbjct: 2344 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKN 2403
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L C+ +G P+ W +G + + + IL G L + T +D G Y C NA
Sbjct: 2404 SVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNA 2463
Score = 77.0 bits (181), Expect = 1e-13
Identities = 79/312 (25%), Positives = 128/312 (41%), Gaps = 26/312 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADR 100
A +Y C + G N+ VY + P E ++ G ++ L C V
Sbjct: 2265 AALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPT 2324
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
++ W+ D ++ G + LD+G L + + SD R++C V + G+
Sbjct: 2325 VT---WMKDGH-PLIKAKGVEI--LDEGHILQLKNIHVSDT-GRYVC-VAVNVAGMTDKK 2376
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
L H P + S E S + V L C P+P+ WF +
Sbjct: 2377 YDLSVHA----PPSIIGNHRSPENIS--VVEKNSVSLTCEASGIPLPSTTWFKDGW---- 2426
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-- 276
P+ +L R+L G +L + + EDAG++ C + N G E F L V P +
Sbjct: 2427 PV---SLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVG 2483
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHK 336
E ++ K K + L C+V G+P+ + W +G+ L+ +E I+ G L I N
Sbjct: 2484 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2543
Query: 337 DDQGIYQCFASN 348
G Y C AS+
Sbjct: 2544 PHTGRYTCLASS 2555
Score = 77.0 bits (181), Expect = 1e-13
Identities = 50/169 (29%), Positives = 77/169 (45%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L C +A P P W+ ++ +T + L D +L I+K D
Sbjct: 3072 VREGTSVSLECESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 3125
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 3126 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 3185
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 3186 WLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3234
Score = 74.1 bits (174), Expect = 7e-13
Identities = 53/195 (27%), Positives = 80/195 (41%), Gaps = 8/195 (4%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVG-QDVRLPCAVHAWPVPTYRWFFEHHE 216
A NT H E V P + S R+ V + V L C + P P+ W +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
T + R+L I K EDAGR+ C N G H L V EP S+
Sbjct: 1867 VNTAQGNLKIQSSGRVLQ-----IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSL 1921
Query: 277 RTKPEVLRSKP--KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
++L + + L+CK G+P+ ++ W + L + + L G + I++
Sbjct: 1922 EDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESA 1981
Query: 335 HKDDQGIYQCFASNA 349
D GIY+C A N+
Sbjct: 1982 QISDAGIYKCVAINS 1996
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/164 (28%), Positives = 71/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W + PI+ T ++ G L I + + D
Sbjct: 2979 VNNFISLTCEVSGFPPPDLSWL----KNXQPIKLNT---NTLIVPGGRTLQIIRAKVSDG 3031
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+C+ N P +
Sbjct: 3032 GEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPV 3091
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 3092 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3135
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 3946 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 3996
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 3997 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 4051
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 4052 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 4100
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 4101 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4153
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 4154 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 4213
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 4214 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 4245
Score = 71.3 bits (167), Expect = 5e-12
Identities = 78/303 (25%), Positives = 129/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 4147 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 4203
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 4204 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 4259
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 4260 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 4308
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG ++ F + P+ P
Sbjct: 4309 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIE 4362
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 4363 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 4421
Query: 346 ASN 348
A+N
Sbjct: 4422 ATN 4424
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 3619 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 3670
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 3671 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3730
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 3731 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 3789
Score = 70.1 bits (164), Expect = 1e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 807 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 862
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 863 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 914
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 915 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 1027
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 1028 FSAGADG-SLYVVSPEGEESGEYVCTATNTAGYA 1060
Score = 68.1 bits (159), Expect = 5e-11
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 13/168 (7%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
+++ Q V L C V PVP W H+ P++E + ++ G L I V+
Sbjct: 2491 KVKEKQSVTLTCEVTGNPVPEITW----HKDGQPLQED---EAHHIISGGRFLQITNVQV 2543
Query: 246 EDAGRFVCWLNNTVGSESVHFTL-IVTEP----ISVRTKPEVLRSKPKSDIALDCKVNGH 300
GR+ C ++ G +S F+L + P + PE + S +L C+ +
Sbjct: 2544 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSY 2603
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + W +G LE N I IL G L I N +D+ G Y C A+N
Sbjct: 2604 PPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATN 2651
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 3533 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 3585
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 3586 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 3645
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 3646 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 3697
Score = 67.3 bits (157), Expect = 8e-11
Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
+ +DV L C V P P WF + LLD G +L ++ RR D
Sbjct: 1467 LNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNV------ELLDRGQVLHLKNARRNDK 1520
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
GR+ C ++N G ++ L + P S++ + S I L+CK G P+ +
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAIT 1580
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G+ + + + ++ G LHI D Y C +N A
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA 1627
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 3835 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 3893
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 3894 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 3942
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 3943 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 3997
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 3998 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 4057
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 4058 MCVAQNPAGTALG 4070
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 907
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 964
Score = 66.1 bits (154), Expect = 2e-10
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R R L L ++ V+ DAG + C +++ GS + L V EP V P+
Sbjct: 567 RIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGG 626
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
S++++ C G+P + W N + + R + DG L IKN D GIY C ASN
Sbjct: 627 SEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASN 685
Query: 349 A 349
+
Sbjct: 686 S 686
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/374 (23%), Positives = 147/374 (39%), Gaps = 42/374 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGS-LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKN 61
W + D PV SLS +IL G L ++ T E A Y C +R++ G
Sbjct: 2421 WFK-DGWPV-SLSNSVRILSGGRMLRLMQTTME------DAGQYTCVVRNAAGEERKIFG 2472
Query: 62 IHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSK 121
+ V E + D V +V L C V + I+ W D +
Sbjct: 2473 LSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT---WHKDGQ----PLQEDE 2525
Query: 122 YHRLDDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
H + G ++ + H R+ C + G ++ +L +V V+ GV +
Sbjct: 2526 AHHIISGGRFLQITNVQVPHTGRYTC-LASSPAGHKSRSFSL--NVFVSPTIAGVGSDGN 2582
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLS 239
E + + + L C +++P T WF + TP+E + R+L G L
Sbjct: 2583 PEDVT--VILNSPTSLVCEAYSYPPATITWFKDG----TPLESN---RNIRILPGGRTLQ 2633
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--------KPEVLRSKPKSDI 291
I + ++AGR+ C N G H+ + V P + P+ ++ K + +
Sbjct: 2634 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2693
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C+ P + W +G+ L+ ++ + I +G L IK D G Y C ASN
Sbjct: 2694 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA- 2752
Query: 352 QAYGMSEYLFDGNV 365
G E FD N+
Sbjct: 2753 ---GEDELDFDVNI 2763
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 10/173 (5%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
++ + + + L C +A P PT W+ + H LT ++ + R+L I + +
Sbjct: 2787 AKDVIINNPISLYCETNAAPPPTLTWYKDGHP-LTSSDKVLILPGGRVLQ-----IPRAK 2840
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK----PEVLRSKPKSDIALDCKVNGH 300
EDAGR+ C N G +S+ + + V P + PE + ++C +G
Sbjct: 2841 VEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGS 2900
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P W +G+ L ++ + L +G L I NT D G Y C A N A
Sbjct: 2901 PAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2953
Score = 65.7 bits (153), Expect = 2e-10
Identities = 70/251 (27%), Positives = 108/251 (43%), Gaps = 26/251 (10%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRD---KITGIRTAVNTLVSHVIVTEPKG-----GVK 176
L DG + S NR + ++ D + TG T T V+ TE K V
Sbjct: 2138 LKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK--TEKKNYNVNIWVP 2195
Query: 177 PRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P + ++ V G + L C P P W ++ +P+ ++ R R+L
Sbjct: 2196 PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW----KKKGSPVLTDSMG-RVRILS 2250
Query: 235 EGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV----TEPISVRTKPEVLRSKPKS 289
G L I + DA + C +N G+ + L V T S E++ ++ KS
Sbjct: 2251 GGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS 2310
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
I+L+C+V G P V W+ +G L + +EIL++G L +KN H D G Y C A N
Sbjct: 2311 -ISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNV 2369
Query: 350 ---RDQAYGMS 357
D+ Y +S
Sbjct: 2370 AGMTDKKYDLS 2380
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 4364 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 4416
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 4417 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 4476
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 4477 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 4514
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 3491 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3550
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 3551 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 3604
Score = 62.9 bits (146), Expect = 2e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 3259 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 3313
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 3314 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTPPP 3373
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 3374 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3418
Score = 62.5 bits (145), Expect = 2e-09
Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 2/125 (1%)
Query: 231 RLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV-RTKPEVLRSKPK 288
+ L G +L I + D GR+VC NT GS +F L V P SV K E L
Sbjct: 2921 KFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2980
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ I+L C+V+G P + WL N + ++ N I+ G L I D G Y C A N
Sbjct: 2981 NFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3040
Query: 349 ARDQA 353
++
Sbjct: 3041 XAGES 3045
Score = 62.5 bits (145), Expect = 2e-09
Identities = 49/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++++++ E + R+L
Sbjct: 3150 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNYKRI----ENSDSLEVRIL 3204
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 3205 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 3264
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 3265 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 3324
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 3325 PAGEEDRIFNLNVYV 3339
Score = 62.1 bits (144), Expect = 3e-09
Identities = 87/360 (24%), Positives = 136/360 (37%), Gaps = 45/360 (12%)
Query: 3 WLQSDNTPVAS----LSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAM 58
W + DN P+ S +S + Q L+ G+L IL L+ D Y C + G I
Sbjct: 826 WRRLDNMPIFSRPFSVSSISQ-LRTGALFIL----NLWASD--KGTYICEAENQFGKIQS 878
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ V ++ + VI G + L C + + I W+ N L
Sbjct: 879 ETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLL--AGNPIPERRWIK----NSAMLL 932
Query: 119 GSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKP 177
+ Y + DGSL+I V D + C V + G ++V HV+ T G
Sbjct: 933 QNPYITVRSDGSLHIERVQLQDG-GEYTC-VASNVAGTNNKTTSVVVHVLPTIQHG---- 986
Query: 178 RVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL 237
Q+ G V LPC P P+ W + + T+ K + D G
Sbjct: 987 -----QQILSTIEGIPVTLPCKASGNPKPSVIW-----SKKGELISTSSAKFSAGAD-GS 1035
Query: 238 LSIQKVRREDAGRFVCWLNNTVG--SESVHFTLIVTEPIS------VRTKPEVLRSKPKS 289
L + E++G +VC NT G V T+ V + + KP +
Sbjct: 1036 LYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGE 1095
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++ L C+V P ++ W + + P + R L G + I T D G+Y C A+N
Sbjct: 1096 EVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATN 1154
Score = 60.1 bits (139), Expect = 1e-08
Identities = 40/163 (24%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V V+L C PVP W+ ++ L+ T R +++D I+ + D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNC-LLSGSTSMTFLNRGQIID-----IESAQISD 1985
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ G+ + ++L V S+ ++ + + L+C+ G P + W
Sbjct: 1986 AGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 308 LHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L +G + + +++L G L + +T D G Y C A NA
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNA 2088
Score = 59.7 bits (138), Expect = 2e-08
Identities = 69/287 (24%), Positives = 119/287 (41%), Gaps = 25/287 (8%)
Query: 71 PWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
P + VP+ + G VL C++ A + T ND D+ + ++ L + S
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIIS--AVDYNLTWQRNDRDVRLAE--PARIRTLANLS 575
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L + +V +D + C V + G +A + ++ V EP P+V+V +++
Sbjct: 576 LELKSVKFNDA-GEYHCMVSSE--GGSSAASVFLT---VQEP-----PKVTVMPKNQSFT 624
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G +V + C+ +P P W + R R+ +G L I+ +DAG
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGS-------HRYRMTSDGTLFIKNAAPKDAG 677
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N+ G++ + TL E + L ++CK +G P V W
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737
Query: 310 NGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNARDQAYG 355
L P+ + I++ L L I+ T D G Y C A N +A G
Sbjct: 738 GDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATG 783
Score = 58.4 bits (135), Expect = 4e-08
Identities = 65/243 (26%), Positives = 99/243 (40%), Gaps = 19/243 (7%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
DG+L I + SD + C V I G TL HV ++P + + R
Sbjct: 1223 DGTLSIDQATPSDA-GIYTC-VATNIAGTDETEITL--HVQEPPTVEDLEPPYNTTFQER 1278
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRR 245
Q + PC P PT +W E LT E +L+EG LL I V
Sbjct: 1279 V--ANQRIEFPCPAKGTPKPTIKWLHNGRE-LTGREPGI-----SILEEGTLLVIASVTP 1330
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR-SKPKSDIA-LDCKVNGHPIE 303
D G ++C N G+ + L V P ++ K +V S + + L C+V G P
Sbjct: 1331 YDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSP 1390
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
++ W + + + I+ + +G L + +D G Y C A N G S+ F+
Sbjct: 1391 IIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIA----GTSQKYFNI 1446
Query: 364 NVL 366
+VL
Sbjct: 1447 DVL 1449
Score = 56.8 bits (131), Expect = 1e-07
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV--LRSKPKSDIALDC 295
L I + D G+++C + G + + + + V P ++ E + + LDC
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P + WL +G+ ++ + +IL +G +L I + G+Y+C A+N
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Score = 56.0 bits (129), Expect = 2e-07
Identities = 37/159 (23%), Positives = 71/159 (44%), Gaps = 11/159 (6%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFV 252
++L C P+P W+ + PI ++ +A +D+G L I + + D+ +
Sbjct: 1565 IKLECKTRGLPMPAITWYKDGQ----PIMSSS---QALYIDKGQYLHIPRAQVSDSATYT 1617
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP---KSDIALDCKVNGHPIELVYWLH 309
C + N G+ F + V P + +K + L+C G+P ++ WL
Sbjct: 1618 CHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPILTWLK 1677
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G ++ N+ I G +L I + + D+G Y C A++
Sbjct: 1678 DGVPVKANDNFRIEAGGKKLEIMSAQEIDRGQYICVATS 1716
Score = 55.2 bits (127), Expect = 3e-07
Identities = 76/348 (21%), Positives = 130/348 (37%), Gaps = 31/348 (8%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
WL+ D PV + G +I +G +L L A Y C ++ G +
Sbjct: 1860 WLKDDQ-PVNTAQGNLKIQSSG--RVLQIAKTLLED---AGRYTCVATNAAGETQQHIQL 1913
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKY 122
HV+ S + +E V+ N V L C + + W D N L +
Sbjct: 1914 HVHEPPSLEDAGKMLNETVLVSNPVQLECKA---AGNPVPVITWYKD---NCLLSGSTSM 1967
Query: 123 HRLDDGSLY-ISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSV 181
L+ G + I + SD + C A+N+ + + + V P +S
Sbjct: 1968 TFLNRGQIIDIESAQISDA-GIYKC----------VAINSAGATELFYSLQVHVAPSISG 2016
Query: 182 EQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSI 240
+ V VRL C P P+ W + +P+ + ++L G +L++
Sbjct: 2017 SNNMVAVVVNNPVRLECEARGIPAPSLTWLKDG----SPVSSFS--NGLQVLSGGRILAL 2070
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
+ D GR+ C N G + L V P ++ + + + + L C+ +
Sbjct: 2071 TSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI 2130
Query: 301 PIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P + WL +G L + I E+ L I++ D G Y C A+N
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 4129 LSSGSLQIAFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 4177
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 4178 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 4231
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 4232 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4291
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 4292 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 4334
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 3760 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3819
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 3820 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3879
Query: 347 SN 348
+N
Sbjct: 3880 TN 3881
Score = 52.4 bits (120), Expect = 2e-06
Identities = 78/313 (24%), Positives = 125/313 (39%), Gaps = 39/313 (12%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV--PDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + S G A S V+ + P +V V ++ G+ V + C + +I+
Sbjct: 589 YHCMVSSEGGSSAAS----VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIA 644
Query: 103 STEWLNDDDINVLHYLGS-KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
T +N + +GS +Y DG+L+I + D + C + + N+
Sbjct: 645 WT-------VNDMFIVGSHRYRMTSDGTLFIKNAAPKDA-GIYGCLASNSAGTDKQ--NS 694
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+ ++ P++ V Q + +G + C P P +WF + +L P
Sbjct: 695 TLRYIEA--------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP- 744
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+T LL GLL IQ+ + DAG + C N G + TL V P +P
Sbjct: 745 --STFLIIDPLL--GLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPA 800
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTH 335
+ + S++ L C V G+P + W L N R + I L G L I N
Sbjct: 801 DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLW 858
Query: 336 KDDQGIYQCFASN 348
D+G Y C A N
Sbjct: 859 ASDKGTYICEAEN 871
Score = 52.0 bits (119), Expect = 3e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 3357 VDTSINIECRXTGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 3409
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 3410 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3469
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 3470 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3511
Score = 50.8 bits (116), Expect = 7e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 18/174 (10%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
+I+V + L C +A P + W+ + + L + + L I++ +
Sbjct: 2686 KIKVNNTLTLECEAYAIPSASLSWY-KDGQPLKSDDHVNIAANGHTLQ-----IKEAQIS 2739
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV------LRSKPKSD------IALD 294
D GR+ C +N G + + F + + P S + E+ R+ D I+L
Sbjct: 2740 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2799
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+ N P + W +G L ++++ IL G L I +D G Y C A N
Sbjct: 2800 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2853
Score = 40.7 bits (91), Expect = 0.008
Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ + VY ++ P ++ + GNA+ L C V D
Sbjct: 4327 YVCTAENSVGFVKATG--FVYVKEPPVFKGDYPSNWIEPLGGNAI-LNCEVK---GDPTP 4380
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 4381 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 4435
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 4436 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 4479
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 4480 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4527
Score = 37.1 bits (82), Expect = 0.098
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 3/113 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I KV D G + C ++ G+ V+EP V P + P L C +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 298 NGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W N R + E RI L + L L +K+ +D G Y C S+
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLAN-LSLELKSVKFNDAGEYHCMVSS 595
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1b protein.
Length = 1842
Score = 83.8 bits (198), Expect = 9e-16
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 9/165 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
V ++LPC +P+P RW + P+ + W + R+ L+I +R ED+G
Sbjct: 28 VNDSLQLPCTAPGYPIPAIRWLKDGR----PLPADSRWTK-RITG---LTISDLRTEDSG 79
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
++C + NT GS L+V +P+ V P+ L++ S + L C + G P + W
Sbjct: 80 TYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYR 139
Query: 310 NGRTLEPNERIEILE-DGLRLHIKNTHKDDQGIYQCFASNARDQA 353
N + P+E I I L I + K G YQCFA+ A
Sbjct: 140 NTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTA 184
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 8/172 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ L CA P PT W + + T + + D
Sbjct: 197 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRT--NQYTMSDGT 254
Query: 237 LLSIQKV---RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL 293
+S V + D G + C N VGS + V P S+R + + D +
Sbjct: 255 TISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR-DTLI 313
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+C+V G+P + W + L N R + E+G L + + K D+G Y C
Sbjct: 314 NCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG-TLKLTDVQKGMDEGEYLC 364
Score = 45.6 bits (103), Expect = 3e-04
Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 16/195 (8%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFE----HHEQLTPIEETTLWKRA 230
V PR V+ ++ G+ L C+V +P P W + +Q P+ T R
Sbjct: 477 VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG---RI 533
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKS 289
++L L I+ V ED G ++C +N VG++ S L V P + + P +
Sbjct: 534 QILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGH 593
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDG----LRLHIKNTHKDDQGI 341
L+C G ++ W ++P+ I ++G L +K + D
Sbjct: 594 AKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVF 653
Query: 342 YQCFASNARDQAYGM 356
+ C A N+ + G+
Sbjct: 654 FSCHAINSYGEDRGL 668
Score = 44.8 bits (101), Expect = 5e-04
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRF 251
+DVRLPC P P +W + + P+ ++ + G L ++ V+ ED+G +
Sbjct: 1094 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPV---SMDGHRLIHTNGTLLLRAVKAEDSGYY 1150
Query: 252 VCWLNNTVGSESVHFTLIVTEP 273
C NT G +++ L+V P
Sbjct: 1151 TCTATNTGGFDTIIVNLLVQVP 1172
Score = 36.7 bits (81), Expect = 0.13
Identities = 41/179 (22%), Positives = 70/179 (39%), Gaps = 15/179 (8%)
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
V++ + + +G V L CA+ P T RW + + E + P E ++ R L L
Sbjct: 106 VTLTPKKLKTGIGSTVILSCALTGSPEFTIRW-YRNTELVLPDEAISI----RGLSNETL 160
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS--KPKSDIALDCK 296
I ++ +G + C+ + F +I E + R P +L C
Sbjct: 161 LITSAQKSHSGAYQCFATRK-AQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCA 219
Query: 297 VNGHPIELVYWLHNGRTL--EPNERIE--ILEDGLRL-HIKNTHKD--DQGIYQCFASN 348
G P V W + + + + R + DG + H+ T D G+Y+C A N
Sbjct: 220 AKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARN 278
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 111 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 167
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 168 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 221
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 222 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 279
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 280 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 335 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 391
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 392 SNVQPSDTMVTQCEARN 408
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 310 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 365
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 366 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 416
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 417 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 471
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 472 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 527
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 528 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 586
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 587 GNYSCVASTELDVVESRAQLLVVGS 611
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 91 HSGSFTITGNNSNFAQRFQGIYRCFASN 118
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 351 DQA 353
A
Sbjct: 319 GSA 321
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 111 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 167
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 168 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 221
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 222 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 279
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 280 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 335 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 391
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 392 SNVQPSDTMVTQCEARN 408
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 310 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 365
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 366 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 416
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 417 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 471
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 472 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 527
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 528 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 586
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 587 GNYSCVASTELDVVESRAQLLVVGS 611
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 91 HSGSFTITGNNSNFAQRFQGIYRCFASN 118
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 351 DQA 353
A
Sbjct: 319 GSA 321
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 111 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 167
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 168 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 221
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 222 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 279
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 280 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 335 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 391
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 392 SNVQPSDTMVTQCEARN 408
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 310 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 365
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 366 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 416
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 417 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 471
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 472 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 527
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 528 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 586
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 587 GNYSCVASTELDVVESRAQLLVVGS 611
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 91 HSGSFTITGNNSNFAQRFQGIYRCFASN 118
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 351 DQA 353
A
Sbjct: 319 GSA 321
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 106 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 162
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 163 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 216
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 217 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 274
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 275 SGPMPADRATYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 329
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 330 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 386
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 387 SNVQPSDTMVTQCEARN 403
Score = 64.1 bits (149), Expect = 7e-10
Identities = 76/325 (23%), Positives = 133/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 305 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 360
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 361 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 411
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 412 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 466
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L VT+ + P
Sbjct: 467 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVTDATQITQGPRST 522
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 523 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 581
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 582 GNYSCVASTELDVVESRAQLLVVGS 606
Score = 38.3 bits (85), Expect = 0.042
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 26 LMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 85
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 86 HSGSFTITGNNSNFAQRFQGIYRCFASN 113
Score = 32.7 bits (71), Expect = 2.1
Identities = 16/63 (25%), Positives = 26/63 (41%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R L + ++D G Y+C A N+
Sbjct: 255 LVLECIAEGFPTPTIKWLRPSGPM-PADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSL 313
Query: 351 DQA 353
A
Sbjct: 314 GSA 316
>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 111 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 167
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 168 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 221
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 222 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 279
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 280 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 335 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 391
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 392 SNVQPSDTMVTQCEARN 408
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 310 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 365
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 366 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 416
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 417 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 471
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 472 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 527
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 528 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 586
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 587 GNYSCVASTELDVVESRAQLLVVGS 611
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 91 HSGSFTITGNNSNFAQRFQGIYRCFASN 118
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
Query: 351 DQA 353
A
Sbjct: 319 GSA 321
>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1255
Score = 83.4 bits (197), Expect = 1e-15
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 109 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 165
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C G RT +
Sbjct: 166 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQ 219
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +W
Sbjct: 220 KEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL--RP 277
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 278 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 332
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 333 WLH-KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 389
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 390 SNVQPSDTMVTQCEARN 406
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 308 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 363
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 364 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 414
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 415 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 469
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 470 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 525
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 526 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 584
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 585 GNYSCVASTELDVVESRAQLLVVGS 609
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 29 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 88
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 89 HSGSFTITGNNSNFAQRFQGIYRCFASN 116
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 258 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 316
Query: 351 DQA 353
A
Sbjct: 317 GSA 319
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 81.8 bits (193), Expect = 3e-15
Identities = 74/277 (26%), Positives = 115/277 (41%), Gaps = 15/277 (5%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR 143
G VVL C PPH + S W+ ++ + + ++ + G LYIS V SD N
Sbjct: 29 GQGVVLLCGPPPHSGE--LSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGN- 85
Query: 144 FLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE-QRSRRIRVGQDVRLPCAVHA 202
+ C V +T R + + G +P++ V+ + G V+L C
Sbjct: 86 YTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALG 145
Query: 203 WPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE 262
P+P W + L + L K + G+L I ++EDAG + C N+ G
Sbjct: 146 NPIPQINW--RRSDGLPFSSKIKLRKFS-----GVLEIPNFQQEDAGSYECIAENSRGKN 198
Query: 263 SVHFTL-IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIE 321
L +P V+ +V + + +C+ +G P WL NG L ER +
Sbjct: 199 VARGRLTYYAKPHWVQLIKDV-EIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQ 257
Query: 322 ILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
I E+G L I N D G++QC A N Y +E
Sbjct: 258 I-ENG-ALTISNLSVTDSGMFQCIAENKHGLVYSSAE 292
Score = 63.3 bits (147), Expect = 1e-09
Identities = 86/372 (23%), Positives = 144/372 (38%), Gaps = 41/372 (11%)
Query: 1 MDWLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK 60
++W +SD P +S LR+ +G LEI F E A Y C +S G
Sbjct: 151 INWRRSDGLPFSSKIKLRKF--SGVLEIPNFQQE------DAGSYECIAENSRGKNVARG 202
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
+ YA W + D + +++ C S WL + VL
Sbjct: 203 RLTYYA--KPHWVQLIKDVEIAVEDSLYWECRAS---GKPKPSYRWLKNGAALVLE---- 253
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+ ++++G+L IS +S +D F C +K + ++ V+ + P P
Sbjct: 254 ERTQIENGALTISNLSVTDS-GMFQCIAENKHGLVYSSAEL---KVVASAPDFSKNPMKK 309
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+ Q ++VG V L C A P W + ++E +R LL++G L I
Sbjct: 310 LVQ----VQVGSLVSLDCKPRASPRALSSW----KKGDVSVQEH---ERISLLNDGGLKI 358
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
V + DAG + C N G + L+VTEP + P + + L C+V
Sbjct: 359 ANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHD 418
Query: 301 P-IELVY-WLHNGRTLEPN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
P +++++ W NG + E++ G L I+N G Y C D
Sbjct: 419 PLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSG-DLMIRNIQLKHSGKYVCMVQTGVDS 477
Query: 353 AYGMSEYLFDGN 364
++ + G+
Sbjct: 478 VSSAADLIVRGS 489
Score = 50.0 bits (114), Expect = 1e-05
Identities = 49/176 (27%), Positives = 77/176 (43%), Gaps = 19/176 (10%)
Query: 188 IRVGQDVRLPCAV--HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+R GQ V L C H+ + +Y W F + +EE + +R + G L I KV
Sbjct: 26 VREGQGVVLLCGPPPHSGEL-SYAWIFNEYPSF--VEEDS--RRFVSQETGHLYISKVEP 80
Query: 246 EDAGRFVCWLNNTVGSESV--HFTLIVT---------EPISVRTKPEVLRSKPKSDIALD 294
D G + C + + V + V T +V EP PE L + S + L+
Sbjct: 81 SDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLE 140
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
C G+PI + W L + +I++ + L I N ++D G Y+C A N+R
Sbjct: 141 CFALGNPIPQINW-RRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSR 195
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 81.4 bits (192), Expect = 5e-15
Identities = 76/280 (27%), Positives = 115/280 (41%), Gaps = 27/280 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
++ V+ AV RC V D + W DD +Y DD +L I +
Sbjct: 233 NQVVLEEEAVEFRCQVQ---GDPQPTVRWKKDD----ADLPRGRYDIKDDYTLRIKKTMS 285
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+D ++C +++ G A TL V P P+ V R + + G+ V P
Sbjct: 286 TDE-GTYMCIAENRV-GKMEASATLT----VRAP-----PQFVVRPRDQIVAQGRTVTFP 334
Query: 198 CAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C P P W E + L P + R + G L+I ++R DAG ++C
Sbjct: 335 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 394
Query: 257 NTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHN 310
GS L VT+ ++ R P +L+ +A+D CK G P+ ++ WL
Sbjct: 395 TVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKE 454
Query: 311 GRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
G T + R I E G L IKN D G Y C A+++
Sbjct: 455 GFTFPGRDPRATIQEQG-TLQIKNLRISDTGTYTCVATSS 493
Score = 51.6 bits (118), Expect = 4e-06
Identities = 49/181 (27%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W+ + T ++ LL G
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR--SHRMLLPSG 88
Query: 237 LLSIQKV---RRE--DAGRFVCWLNNTVGSE-SVHFTL-IVTEPISVRTKPEVLRSKPKS 289
L ++ RR D G +VC N +G S + +L + R P +
Sbjct: 89 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 148
Query: 290 DIALDCKV-NGHPIELVYWLHNG-RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
L+C+ GHP +YW + R + ERI I G +L I NT K D G+Y C +
Sbjct: 149 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIR--GGKLMISNTRKSDAGMYTCVGT 206
Query: 348 N 348
N
Sbjct: 207 N 207
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
G L I R+ DAG + C N VG +S L V E + +P + +
Sbjct: 186 GKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFR 245
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+V G P V W + L P R +I +D L IK T D+G Y C A N
Sbjct: 246 CQVQGDPQPTVRWKKDDADL-PRGRYDI-KDDYTLRIKKTMSTDEGTYMCIAEN 297
Score = 35.5 bits (78), Expect = 0.30
Identities = 51/233 (21%), Positives = 82/233 (35%), Gaps = 21/233 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C + VG + S + V A + V D+ V G V C + +
Sbjct: 291 YMCIAENRVGKMEASATLTVRAP--PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-- 346
Query: 105 EWLNDDDINVL-----HYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
W + N+L S+ G L I+ + SD ++C+ I
Sbjct: 347 -WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDA-GYYICQALTVAGSILAKA 404
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
V+ V+ P P + ++ + V L C P+P W E
Sbjct: 405 QLEVTDVLTDRPP----PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFT--F 458
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P + RA + ++G L I+ +R D G + C ++ G S L VTE
Sbjct: 459 PGRDP----RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 81.4 bits (192), Expect = 5e-15
Identities = 76/280 (27%), Positives = 115/280 (41%), Gaps = 27/280 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
++ V+ AV RC V D + W DD +Y DD +L I +
Sbjct: 249 NQVVLEEEAVEFRCQVQ---GDPQPTVRWKKDD----ADLPRGRYDIKDDYTLRIKKTMS 301
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+D ++C +++ G A TL V P P+ V R + + G+ V P
Sbjct: 302 TDE-GTYMCIAENRV-GKMEASATLT----VRAP-----PQFVVRPRDQIVAQGRTVTFP 350
Query: 198 CAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C P P W E + L P + R + G L+I ++R DAG ++C
Sbjct: 351 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 410
Query: 257 NTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHN 310
GS L VT+ ++ R P +L+ +A+D CK G P+ ++ WL
Sbjct: 411 TVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKE 470
Query: 311 GRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
G T + R I E G L IKN D G Y C A+++
Sbjct: 471 GFTFPGRDPRATIQEQG-TLQIKNLRISDTGTYTCVATSS 509
Score = 51.6 bits (118), Expect = 4e-06
Identities = 49/181 (27%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W+ + T ++ LL G
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR--SHRMLLPSG 104
Query: 237 LLSIQKV---RRE--DAGRFVCWLNNTVGSE-SVHFTL-IVTEPISVRTKPEVLRSKPKS 289
L ++ RR D G +VC N +G S + +L + R P +
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 164
Query: 290 DIALDCKV-NGHPIELVYWLHNG-RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
L+C+ GHP +YW + R + ERI I G +L I NT K D G+Y C +
Sbjct: 165 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIR--GGKLMISNTRKSDAGMYTCVGT 222
Query: 348 N 348
N
Sbjct: 223 N 223
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
G L I R+ DAG + C N VG +S L V E + +P + +
Sbjct: 202 GKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFR 261
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+V G P V W + L P R +I +D L IK T D+G Y C A N
Sbjct: 262 CQVQGDPQPTVRWKKDDADL-PRGRYDI-KDDYTLRIKKTMSTDEGTYMCIAEN 313
Score = 35.5 bits (78), Expect = 0.30
Identities = 51/233 (21%), Positives = 82/233 (35%), Gaps = 21/233 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C + VG + S + V A + V D+ V G V C + +
Sbjct: 307 YMCIAENRVGKMEASATLTVRAP--PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-- 362
Query: 105 EWLNDDDINVL-----HYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
W + N+L S+ G L I+ + SD ++C+ I
Sbjct: 363 -WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDA-GYYICQALTVAGSILAKA 420
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
V+ V+ P P + ++ + V L C P+P W E
Sbjct: 421 QLEVTDVLTDRPP----PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFT--F 474
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P + RA + ++G L I+ +R D G + C ++ G S L VTE
Sbjct: 475 PGRDP----RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 523
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 81.4 bits (192), Expect = 5e-15
Identities = 76/280 (27%), Positives = 115/280 (41%), Gaps = 27/280 (9%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
++ V+ AV RC V D + W DD +Y DD +L I +
Sbjct: 235 NQVVLEEEAVEFRCQVQ---GDPQPTVRWKKDD----ADLPRGRYDIKDDYTLRIKKTMS 287
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+D ++C +++ G A TL V P P+ V R + + G+ V P
Sbjct: 288 TDE-GTYMCIAENRV-GKMEASATLT----VRAP-----PQFVVRPRDQIVAQGRTVTFP 336
Query: 198 CAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C P P W E + L P + R + G L+I ++R DAG ++C
Sbjct: 337 CETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL 396
Query: 257 NTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHN 310
GS L VT+ ++ R P +L+ +A+D CK G P+ ++ WL
Sbjct: 397 TVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKE 456
Query: 311 GRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
G T + R I E G L IKN D G Y C A+++
Sbjct: 457 GFTFPGRDPRATIQEQG-TLQIKNLRISDTGTYTCVATSS 495
Score = 51.6 bits (118), Expect = 4e-06
Identities = 49/181 (27%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W+ + T ++ LL G
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR--SHRMLLPSG 90
Query: 237 LLSIQKV---RRE--DAGRFVCWLNNTVGSE-SVHFTL-IVTEPISVRTKPEVLRSKPKS 289
L ++ RR D G +VC N +G S + +L + R P +
Sbjct: 91 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 150
Query: 290 DIALDCKV-NGHPIELVYWLHNG-RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
L+C+ GHP +YW + R + ERI I G +L I NT K D G+Y C +
Sbjct: 151 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIR--GGKLMISNTRKSDAGMYTCVGT 208
Query: 348 N 348
N
Sbjct: 209 N 209
Score = 51.6 bits (118), Expect = 4e-06
Identities = 37/114 (32%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
G L I R+ DAG + C N VG +S L V E + +P + +
Sbjct: 188 GKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFR 247
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+V G P V W + L P R +I +D L IK T D+G Y C A N
Sbjct: 248 CQVQGDPQPTVRWKKDDADL-PRGRYDI-KDDYTLRIKKTMSTDEGTYMCIAEN 299
Score = 35.5 bits (78), Expect = 0.30
Identities = 51/233 (21%), Positives = 82/233 (35%), Gaps = 21/233 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C + VG + S + V A + V D+ V G V C + +
Sbjct: 293 YMCIAENRVGKMEASATLTVRAP--PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-- 348
Query: 105 EWLNDDDINVL-----HYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
W + N+L S+ G L I+ + SD ++C+ I
Sbjct: 349 -WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDA-GYYICQALTVAGSILAKA 406
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
V+ V+ P P + ++ + V L C P+P W E
Sbjct: 407 QLEVTDVLTDRPP----PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFT--F 460
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P + RA + ++G L I+ +R D G + C ++ G S L VTE
Sbjct: 461 PGRDP----RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 509
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 80.6 bits (190), Expect = 8e-15
Identities = 89/341 (26%), Positives = 142/341 (41%), Gaps = 25/341 (7%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVP 77
+Q L NGSL I + H +Y+C +S+ V A++ P
Sbjct: 23 KQQLSNGSLLIQNILHSRH-HKPDEGLYQCEASLGDSGSIISRTAKV--AVAGPLRFLSQ 79
Query: 78 DEYVIA--GNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISA 134
E V A G+ V+L+C V + + + W N D+ + S+ L G+L IS
Sbjct: 80 TESVTAFMGDTVLLKCEV---IGEPMPTIHWQKNQQDLTPIPG-DSRVVVLPSGALQISR 135
Query: 135 VSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV--GQ 192
+ D + C R+ + RT V I+++P G+ ++ QR + G+
Sbjct: 136 LQPGDI-GIYRCSARNPASS-RTGNEAEVR--ILSDP--GLHRQLYFLQRPSNVVAIEGK 189
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
D L V +P P++ W E++ + K+ LL L I V +D+G +
Sbjct: 190 DAVLEGCVSGYPPPSFTWL--RGEEVIQLRS----KKYSLLGGSNLLISNVTDDDSGMYT 243
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C + + S L V P P L + DI +C V+G P+ V W+ NG
Sbjct: 244 CVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGD 303
Query: 313 TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ P++ +I+ G L I K D+G YQC A N A
Sbjct: 304 VVIPSDYFQIV-GGSNLRILGVVKSDEGFYQCVAENEAGNA 343
Score = 54.0 bits (124), Expect = 8e-07
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 11/176 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G V L C V P+PT W ++ + LTPI + R +L G L I +++ D G
Sbjct: 87 MGDTVLLKCEVIGEPMPTIHWQ-KNQQDLTPIPGDS---RVVVLPSGALQISRLQPGDIG 142
Query: 250 RFVCWLNNTVGSESVHFT--LIVTEP-----ISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
+ C N S + + I+++P + +P + + D L+ V+G+P
Sbjct: 143 IYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPP 202
Query: 303 ELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
WL ++ + L G L I N DD G+Y C + + +E
Sbjct: 203 PSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAE 258
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 79.4 bits (187), Expect = 2e-14
Identities = 80/319 (25%), Positives = 120/319 (37%), Gaps = 17/319 (5%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A VY+C + VG + + I + L + G V+L C P H
Sbjct: 106 AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGL- 164
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
S WL ++ N + G + G+LYI+ + SD N ++ +
Sbjct: 165 -SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSK 223
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
+ E P + + VGQ V L C PVP +W + L+P
Sbjct: 224 FAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWR-KVDGSLSP 282
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTK 279
W A E L I V ED G + C N+ G ++V +IV +P ++
Sbjct: 283 -----QWTTA----EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ + S++ C G P V WL NG L R+E+L LR +D
Sbjct: 334 SDT-EADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLR--FSKLSLEDS 390
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 391 GMYQCVAENKHGTIYASAE 409
Score = 41.5 bits (93), Expect = 0.005
Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
+ V L C A P TYRW E +L P R +L+ L+ + + +DAG
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEP------GSRHQLVGGNLVIMNPTKAQDAGV 108
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPE--VLRSKPKSDIALDCKVNGHPIELVY-W 307
+ C +N VG+ ++ + +K E +++ + L C H L Y W
Sbjct: 109 YQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRW 168
Query: 308 LHN--GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L N + + R + + L+I T+ D G Y C A++ D
Sbjct: 169 LLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMD 214
Score = 40.3 bits (90), Expect = 0.010
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRT-- 313
++ +GS++ + +P+SV E + + L C+ P W NG
Sbjct: 26 SSALGSQTTFGPVFEDQPLSVLFPEE----STEEQVLLACRARASPPATYRWKMNGTEMK 81
Query: 314 LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
LEP R +++ L + + T D G+YQC ASN
Sbjct: 82 LEPGSRHQLVGGNLVI-MNPTKAQDAGVYQCLASN 115
Score = 35.9 bits (79), Expect = 0.23
Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 15/171 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G ++ +PC A P W + T I + R + +G L I+ + R D G+
Sbjct: 433 GGEILIPCQPRAAPKAVVLW-----SKGTEILVNS--SRVTVTPDGTLIIRNISRSDEGK 485
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WL 308
+ C+ N +G + L V + + P ++ L C + P ++L + W
Sbjct: 486 YTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT 545
Query: 309 HNGRTLE---PN---ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ ++ P R + E L I N G Y C A D A
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSA 596
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 79.4 bits (187), Expect = 2e-14
Identities = 80/319 (25%), Positives = 120/319 (37%), Gaps = 17/319 (5%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A VY+C + VG + + I + L + G V+L C P H
Sbjct: 106 AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGL- 164
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
S WL ++ N + G + G+LYI+ + SD N ++ +
Sbjct: 165 -SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSK 223
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
+ E P + + VGQ V L C PVP +W + L+P
Sbjct: 224 FAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWR-KVDGSLSP 282
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTK 279
W A E L I V ED G + C N+ G ++V +IV +P ++
Sbjct: 283 -----QWTTA----EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ + S++ C G P V WL NG L R+E+L LR +D
Sbjct: 334 SDT-EADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLR--FSKLSLEDS 390
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 391 GMYQCVAENKHGTIYASAE 409
Score = 41.5 bits (93), Expect = 0.005
Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
+ V L C A P TYRW E +L P R +L+ L+ + + +DAG
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEP------GSRHQLVGGNLVIMNPTKAQDAGV 108
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPE--VLRSKPKSDIALDCKVNGHPIELVY-W 307
+ C +N VG+ ++ + +K E +++ + L C H L Y W
Sbjct: 109 YQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRW 168
Query: 308 LHN--GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L N + + R + + L+I T+ D G Y C A++ D
Sbjct: 169 LLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMD 214
Score = 40.3 bits (90), Expect = 0.010
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRT-- 313
++ +GS++ + +P+SV E + + L C+ P W NG
Sbjct: 26 SSALGSQTTFGPVFEDQPLSVLFPEE----STEEQVLLACRARASPPATYRWKMNGTEMK 81
Query: 314 LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
LEP R +++ L + + T D G+YQC ASN
Sbjct: 82 LEPGSRHQLVGGNLVI-MNPTKAQDAGVYQCLASN 115
Score = 35.9 bits (79), Expect = 0.23
Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 15/171 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G ++ +PC A P W + T I + R + +G L I+ + R D G+
Sbjct: 433 GGEILIPCQPRAAPKAVVLW-----SKGTEILVNS--SRVTVTPDGTLIIRNISRSDEGK 485
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WL 308
+ C+ N +G + L V + + P ++ L C + P ++L + W
Sbjct: 486 YTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT 545
Query: 309 HNGRTLE---PN---ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ ++ P R + E L I N G Y C A D A
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSA 596
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 79.4 bits (187), Expect = 2e-14
Identities = 89/317 (28%), Positives = 129/317 (40%), Gaps = 31/317 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPW--EVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
+YRC + +G AMS I + A + W E P E V G +VVL C PP A+ +
Sbjct: 111 IYRCFASNKLG-TAMSHEIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPS-AEPL 167
Query: 102 SSTEWLNDDDINVLHYLGSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV- 159
W+N +LH + + +G+LY + V TSD H+ ++C GIRT +
Sbjct: 168 R-IYWMNS---KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--FPGIRTIIQ 221
Query: 160 -NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V T KPR+ S V GQ + L C +P PT +
Sbjct: 222 KEPIDLRVKATNSMIDRKPRLLFPTNSSTHLVALQGQPLVLECIAEGFPTPTIK--SVRP 279
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPI 274
P + T + L + KV ED G + C N++GS ++ + P
Sbjct: 280 SGPMPADRVTYQNHNK-----TLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG---RTLEPNERIEILEDGLRLHI 331
+ KP+ P LDC+V G P V W NG L +++ I L L
Sbjct: 335 WLH-KPQSHLYGPGETARLDCQVEGRPQPEVTWRINGIPVEELAKDQKYRIQRGALIL-- 391
Query: 332 KNTHKDDQGIYQCFASN 348
N D + QC A N
Sbjct: 392 SNVQPSDTMVTQCEARN 408
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 310 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVEGRPQPEVT- 365
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 366 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 416
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 417 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 471
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 472 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 527
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 528 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 586
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 587 GNYSCVASTELDVVESRAQLLVVGS 611
Score = 38.7 bits (86), Expect = 0.032
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL----- 323
++ P+ P L P DI+L C+ +G P W +G +P E + +
Sbjct: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
Query: 324 EDG---LRLHIKNTHKDDQGIYQCFASN 348
G + + N + QGIY+CFASN
Sbjct: 91 HSGSFTITGNNSNFAQRFQGIYRCFASN 118
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 79.4 bits (187), Expect = 2e-14
Identities = 80/319 (25%), Positives = 120/319 (37%), Gaps = 17/319 (5%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A VY+C + VG + + I + L + G V+L C P H
Sbjct: 106 AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGL- 164
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
S WL ++ N + G + G+LYI+ + SD N ++ +
Sbjct: 165 -SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSK 223
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
+ E P + + VGQ V L C PVP +W + L+P
Sbjct: 224 FAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWR-KVDGSLSP 282
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTK 279
W A E L I V ED G + C N+ G ++V +IV +P ++
Sbjct: 283 -----QWTTA----EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ + S++ C G P V WL NG L R+E+L LR +D
Sbjct: 334 SDT-EADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLR--FSKLSLEDS 390
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 391 GMYQCVAENKHGTIYASAE 409
Score = 41.5 bits (93), Expect = 0.005
Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
+ V L C A P TYRW E +L P R +L+ L+ + + +DAG
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEP------GSRHQLVGGNLVIMNPTKAQDAGV 108
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPE--VLRSKPKSDIALDCKVNGHPIELVY-W 307
+ C +N VG+ ++ + +K E +++ + L C H L Y W
Sbjct: 109 YQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRW 168
Query: 308 LHN--GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L N + + R + + L+I T+ D G Y C A++ D
Sbjct: 169 LLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMD 214
Score = 37.1 bits (82), Expect = 0.098
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 7/95 (7%)
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRT-- 313
++ + S++ + +P+SV E + + L C+ P W NG
Sbjct: 26 SSALESQTTFGPVFEDQPLSVLFPEE----STEEQVLLACRARASPPATYRWKMNGTEMK 81
Query: 314 LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
LEP R +++ L + + T D G+YQC ASN
Sbjct: 82 LEPGSRHQLVGGNLVI-MNPTKAQDAGVYQCLASN 115
Score = 35.9 bits (79), Expect = 0.23
Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 15/171 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G ++ +PC A P W + T I + R + +G L I+ + R D G+
Sbjct: 433 GGEILIPCQPRAAPKAVVLW-----SKGTEILVNS--SRVTVTPDGTLIIRNISRSDEGK 485
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WL 308
+ C+ N +G + L V + + P ++ L C + P ++L + W
Sbjct: 486 YTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT 545
Query: 309 HNGRTLE---PN---ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ ++ P R + E L I N G Y C A D A
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSA 596
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 79.4 bits (187), Expect = 2e-14
Identities = 80/319 (25%), Positives = 120/319 (37%), Gaps = 17/319 (5%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A VY+C + VG + + I + L + G V+L C P H
Sbjct: 106 AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGL- 164
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
S WL ++ N + G + G+LYI+ + SD N ++ +
Sbjct: 165 -SYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSK 223
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
+ E P + + VGQ V L C PVP +W + L+P
Sbjct: 224 FAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWR-KVDGSLSP 282
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTK 279
W A E L I V ED G + C N+ G ++V +IV +P ++
Sbjct: 283 -----QWTTA----EPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ + S++ C G P V WL NG L R+E+L LR +D
Sbjct: 334 SDT-EADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLR--FSKLSLEDS 390
Query: 340 GIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 391 GMYQCVAENKHGTIYASAE 409
Score = 41.5 bits (93), Expect = 0.005
Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
+ V L C A P TYRW E +L P R +L+ L+ + + +DAG
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKLEP------GSRHQLVGGNLVIMNPTKAQDAGV 108
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPE--VLRSKPKSDIALDCKVNGHPIELVY-W 307
+ C +N VG+ ++ + +K E +++ + L C H L Y W
Sbjct: 109 YQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRW 168
Query: 308 LHN--GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L N + + R + + L+I T+ D G Y C A++ D
Sbjct: 169 LLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMD 214
Score = 40.3 bits (90), Expect = 0.010
Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 256 NNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRT-- 313
++ +GS++ + +P+SV E + + L C+ P W NG
Sbjct: 26 SSALGSQTTFGPVFEDQPLSVLFPEE----STEEQVLLACRARASPPATYRWKMNGTEMK 81
Query: 314 LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
LEP R +++ L + + T D G+YQC ASN
Sbjct: 82 LEPGSRHQLVGGNLVI-MNPTKAQDAGVYQCLASN 115
Score = 35.9 bits (79), Expect = 0.23
Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 15/171 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G ++ +PC A P W + T I + R + +G L I+ + R D G+
Sbjct: 433 GGEILIPCQPRAAPKAVVLW-----SKGTEILVNS--SRVTVTPDGTLIIRNISRSDEGK 485
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WL 308
+ C+ N +G + L V + + P ++ L C + P ++L + W
Sbjct: 486 YTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT 545
Query: 309 HNGRTLE---PN---ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+ ++ P R + E L I N G Y C A D A
Sbjct: 546 LDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSA 596
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 79.4 bits (187), Expect = 2e-14
Identities = 98/363 (26%), Positives = 134/363 (36%), Gaps = 40/363 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDV---HATVYRCRMRSSVGYIAMS 59
W + D P+ GLR GS P + L+ V Y C R+ G +
Sbjct: 82 WRRGDGQPL----GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAE 137
Query: 60 KNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADR-ISSTEWLNDDDINVLHYL 118
+ V P V+ G V L C+V A R + WL D L
Sbjct: 138 ARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIV---LAGRPLPERHWLKDG--RPLPP- 191
Query: 119 GSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPR 178
GS++ DGSL++ + + R+ C A NT S E V PR
Sbjct: 192 GSRHSIRADGSLHLDR-ALQEHAGRYSC----------VATNTAGSQHRDVELVVQVPPR 240
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
+ G LPC P PT W E + T+ + EG L
Sbjct: 241 IHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL------TSRGPHYNVSKEGTL 294
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEP-ISVRTK-----PEVLRSKPKSDI 291
I + +DAG +VC NTVG S L V T+P I + P + +K ++
Sbjct: 295 LIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEV 354
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
LDC+ G P LV W + R + P R +L G L + D G Y+C ASN
Sbjct: 355 TLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG-SLRLAQVQVGDSGHYECTASNPA 413
Query: 351 DQA 353
A
Sbjct: 414 GSA 416
Score = 74.5 bits (175), Expect = 5e-13
Identities = 58/203 (28%), Positives = 82/203 (40%), Gaps = 4/203 (1%)
Query: 149 RDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTY 208
RD T AVN L + G P+++ R + +G+ L C P PT
Sbjct: 21 RDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTV 80
Query: 209 RWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL 268
W + L R+R D G+L + V ED +VC N G L
Sbjct: 81 TWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARL 140
Query: 269 IVT--EPISVRTKPEVLRSKPKSDIALDCKV-NGHPIELVYWLHNGRTLEPNERIEILED 325
IVT P + + +R ++L C V G P+ +WL +GR L P R I D
Sbjct: 141 IVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD 200
Query: 326 GLRLHIKNTHKDDQGIYQCFASN 348
G LH+ ++ G Y C A+N
Sbjct: 201 G-SLHLDRALQEHAGRYSCVATN 222
Score = 33.1 bits (72), Expect = 1.6
Identities = 31/136 (22%), Positives = 49/136 (36%), Gaps = 8/136 (5%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G L I + DAG + C N +G S L V + P + + L C
Sbjct: 11 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLAC 70
Query: 296 KVNGHPIELVYWLH-NGRTL------EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ G P V W +G+ L R + G+ L ++ +DQ Y C A N
Sbjct: 71 RATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGV-LFFESVAPEDQAPYVCEARN 129
Query: 349 ARDQAYGMSEYLFDGN 364
+ + + G+
Sbjct: 130 VFGKVQAEARLIVTGH 145
>AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ40259 fis, clone TESTI2025486. ).
Length = 600
Score = 79.0 bits (186), Expect = 2e-14
Identities = 67/231 (29%), Positives = 111/231 (48%), Gaps = 20/231 (8%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
+++ DGSL +++VS DR + CR I G AV+T +H++V P V P ++
Sbjct: 28 YQVSDGSLTVTSVSREDR-GAYTCRAYS-IQG--EAVHT--THLLVQGPPFIVSPPENIT 81
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
+ + QD L C A+P TY W+++ + L R R+L +G L I
Sbjct: 82 -----VNISQDALLTCRAEAYPGNLTYTWYWQDENVYF---QNDLKLRVRILIDGTLIIF 133
Query: 242 KVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
+V+ ED+G++ C +N++G S S L V P V P V+ + C V+
Sbjct: 134 RVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAE 193
Query: 301 -PIELVYWLHNGRTLEPNERI--EILEDGLRLHIKNTHKDDQGIYQCFASN 348
P +V W +GR L+ + + ++EDG + I+ ++ G Y C N
Sbjct: 194 PPATVVKWNKDGRPLQVEKNLGWTLMEDG-SIRIEEATEEALGTYTCVPYN 243
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/134 (30%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFT-LIVTEPISVRTKPEVLRSKPKSDI 291
+ +G L++ V RED G + C + G E+VH T L+V P + + PE + D
Sbjct: 30 VSDGSLTVTSVSREDRGAYTCRAYSIQG-EAVHTTHLLVQGPPFIVSPPENITVNISQDA 88
Query: 292 ALDCKVNGHPIELVY-WLHNGRTL----EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ +P L Y W + + R+ IL DG L I +D G Y C
Sbjct: 89 LLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDG-TLIIFRVKPEDSGKYTCVP 147
Query: 347 SNARDQAYGMSEYL 360
SN+ ++ S YL
Sbjct: 148 SNSLGRSPSASAYL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 10/164 (6%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ VG + C V A P T + + L +E+ W L+++G + I++ E
Sbjct: 178 VPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQ-VEKNLGWT---LMEDGSIRIEEATEEA 233
Query: 248 AGRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPE-VLRSKPKSDIALDCKVNGHPIEL 304
G + C NT+G+ +S L++ +P P R + ++ + C G P +
Sbjct: 234 LGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPV 293
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W G+ + L G L + K+D G ++C A+N
Sbjct: 294 ITWRKVGK--PSRSKHSALPSG-SLQFRALSKEDHGEWECVATN 334
Score = 35.5 bits (78), Expect = 0.30
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
+ C G+P +V WL G L + + ++ DG L + + ++D+G Y C A + + +
Sbjct: 1 MTCTAFGNPKPIVTWLKEGTLLGASGKYQV-SDG-SLTVTSVSREDRGAYTCRAYSIQGE 58
Query: 353 AYGMSEYLFDG 363
A + L G
Sbjct: 59 AVHTTHLLVQG 69
Score = 33.5 bits (73), Expect = 1.2
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
R G+++ +PCA P P W + + + K + L G L + + +E
Sbjct: 273 RQEAGRELLIPCAAAGDPFPVITW--------RKVGKPSRSKHS-ALPSGSLQFRALSKE 323
Query: 247 DAGRFVCWLNNTVGS--ESVHFTLIVTEP 273
D G + C N V S S H T+I T P
Sbjct: 324 DHGEWECVATNVVTSITASTHLTVIGTSP 352
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 116 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 175 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 291 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 401
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 402 SRAVYQCNTSN 412
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 428 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 480
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 598
Query: 351 DQ 352
DQ
Sbjct: 599 DQ 600
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 300 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 348
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 349 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 403
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 464 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 510
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 55 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 114
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 115 EYQCFARN 122
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 85 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 143
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 144 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 199
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 200 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 259
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 260 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 312
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 313 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 370
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 371 SRAVYQCNTSN 381
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 397 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 449
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 450 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 509
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 510 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 567
Query: 351 DQ 352
DQ
Sbjct: 568 DQ 569
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 269 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 317
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 318 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 372
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 373 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 432
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 433 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 479
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 24 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 83
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 84 EYQCFARN 91
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 110 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 168
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 169 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 224
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 225 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 284
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 285 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 337
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 338 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 395
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 396 SRAVYQCNTSN 406
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 422 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 474
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 475 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 534
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 535 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 592
Query: 351 DQ 352
DQ
Sbjct: 593 DQ 594
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 294 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 342
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 343 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 397
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 398 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 457
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 458 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 504
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 49 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 108
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 109 EYQCFARN 116
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 116 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 175 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 291 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 401
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 402 SRAVYQCNTSN 412
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 428 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 480
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 598
Query: 351 DQ 352
DQ
Sbjct: 599 DQ 600
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 300 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 348
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 349 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 403
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 464 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 510
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 55 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 114
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 115 EYQCFARN 122
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 116 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 175 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 291 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 401
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 402 SRAVYQCNTSN 412
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 428 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 480
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 598
Query: 351 DQ 352
DQ
Sbjct: 599 DQ 600
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 300 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 348
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 349 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 403
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 464 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 510
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 55 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 114
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 115 EYQCFARN 122
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 78.6 bits (185), Expect = 3e-14
Identities = 75/311 (24%), Positives = 120/311 (38%), Gaps = 21/311 (6%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 116 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 175 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 230
Query: 164 SHVIVTEPKGGVKPRVSVEQ---RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
V+ T P Q S+ + G D+ L C P P W+ + + +
Sbjct: 231 LKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 290
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + +A L I V ED+G + C +N +GS ++ V +P
Sbjct: 291 KAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKD 337
+ L P D L C+ NG+P V W+ NG L+ PN E+ D + ++T
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQIS 401
Query: 338 DQGIYQCFASN 348
+ +YQC SN
Sbjct: 402 SRAVYQCNTSN 412
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 428 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 480
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 481 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 540
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 541 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 598
Query: 351 DQ 352
DQ
Sbjct: 599 DQ 600
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 300 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 348
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 349 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 403
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 464 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 510
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 55 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 114
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 115 EYQCFARN 122
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 77.8 bits (183), Expect = 6e-14
Identities = 48/185 (25%), Positives = 85/185 (45%), Gaps = 10/185 (5%)
Query: 166 VIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT 225
++VTEP VK + S+ ++ G RL C + P WF HE + +
Sbjct: 2082 LLVTEPPKFVKKL----EASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHE----LPASD 2133
Query: 226 LWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
++ + ++ + + ED+G F+C N GS S +IV EP + P ++ +
Sbjct: 2134 KYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVET 2193
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQ 343
++++L+C+++G P V W + R L +++ +I +HI N D G Y
Sbjct: 2194 LKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYH 2253
Query: 344 CFASN 348
C A N
Sbjct: 2254 CKAQN 2258
Score = 74.5 bits (175), Expect = 5e-13
Identities = 45/166 (27%), Positives = 80/166 (48%), Gaps = 6/166 (3%)
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
SR ++ + R C + P W+ + T I+E++ ++ + + +L + +
Sbjct: 3979 SRIVKQDEFTRYECKIGGSPEIKVLWYKDE----TEIQESSKFRMSFVDSVAVLEMHNLS 4034
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C +N GS S +L V EP R KP + + +D+ L+C++ G P
Sbjct: 4035 VEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFH 4094
Query: 305 VYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASN 348
V W + R L ++ +I+ + +HI N D G YQC A+N
Sbjct: 4095 VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATN 4140
Score = 73.3 bits (172), Expect = 1e-12
Identities = 44/168 (26%), Positives = 77/168 (45%), Gaps = 6/168 (3%)
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
+ S+ + G+ ++L C + P WF E + E+ + + + LL+I +
Sbjct: 3036 EASKVAKQGESIQLECKISGSPEIKVSWFRNDSE----LHESWKYNMSFINSVALLTINE 3091
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
ED+G ++C +N VG S L V P KP + + SD+ L C+++G P
Sbjct: 3092 ASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPP 3151
Query: 303 ELVYWLHNGRTLEPNERIEILED--GLRLHIKNTHKDDQGIYQCFASN 348
V W+ + + + +++ +I LHI N D G Y C A+N
Sbjct: 3152 FEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATN 3199
Score = 69.3 bits (162), Expect = 2e-11
Identities = 80/311 (25%), Positives = 128/311 (41%), Gaps = 31/311 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNA-VVLRCVVPPHCADRISS 103
Y C + G+ S ++ V P+ V P + N V L+ +V I
Sbjct: 1410 YTCSATNKAGHNQCSGHLTVK---EPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTI-- 1464
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
+W D+ LH ++ DD S L + A +D ++C++ + + G T+ T
Sbjct: 1465 -KWFKDN--KELHSGAARSVWKDDTSTSLELFAAKATDS-GTYICQLSNDV-GTATSKAT 1519
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
L V EP +K V +R GQ C + P W+ + +E +T I
Sbjct: 1520 L----FVKEPPQFIKKPSPVLV----LRNGQSTTFECQITGTPKIRVSWYLDGNE-ITAI 1570
Query: 222 EETTLWKRARLLDEGLLSIQ--KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK 279
+ K +GL + Q R E++G +VC N G+ S L V EP + +
Sbjct: 1571 Q-----KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 1625
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILE--DGLRLHIKNTHKD 337
+ + SD+ L+C+V G P V WL N R + +++ + + LHI
Sbjct: 1626 LKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPS 1685
Query: 338 DQGIYQCFASN 348
D G YQC SN
Sbjct: 1686 DTGEYQCIVSN 1696
Score = 61.7 bits (143), Expect = 4e-09
Identities = 73/309 (23%), Positives = 122/309 (39%), Gaps = 24/309 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
Y +++ VG + I+V + P + + I G+ + L C+V S
Sbjct: 1314 YTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIV---AGSHPIS 1370
Query: 104 TEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
+W DD +I+ +H + L IS + +D + C +K N
Sbjct: 1371 IQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDS-GTYTCSATNK-----AGHNQC 1423
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
H+ V EP P + +S+ + V+L V T +WF ++ E L
Sbjct: 1424 SGHLTVKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE-LHSGA 1477
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE- 281
++WK L + + D+G ++C L+N VG+ + TL V EP KP
Sbjct: 1478 ARSVWKDDTSTS---LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSP 1534
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQ 339
VL + +C++ G P V W +G + ++ I DGL I ++
Sbjct: 1535 VLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENS 1594
Query: 340 GIYQCFASN 348
G Y C A N
Sbjct: 1595 GTYVCEARN 1603
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/223 (27%), Positives = 91/223 (40%), Gaps = 18/223 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
SL I V +D N F CR + + G + + L IV EP P + S+ +
Sbjct: 834 SLEIIRVDMNDAGN-FTCRATNSV-GSKDSSGAL----IVQEP-----PSFVTKPGSKDV 882
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G V L T RWF + +++L + K A E L + V+ D+
Sbjct: 883 LPGSAVCLKSTFQGSTPLTIRWF-KGNKELVSGGSCYITKEAL---ESSLELYLVKTSDS 938
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-LDCKVNGHPIELVYW 307
G + C ++N G L V EP + K E + K D L CKV G P + W
Sbjct: 939 GTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITW 998
Query: 308 LHNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N R ++ + R+ +E L + + +D G Y C A N
Sbjct: 999 FANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQN 1041
Score = 60.5 bits (140), Expect = 9e-09
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 8/165 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ +G + C + + P ++WF E + ++ ++ + ++ + L I + + D
Sbjct: 132 VALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSI-RSSKYISS--LEILRTQVVD 187
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTE--PISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
G + C +N GS S TL VTE P + ++P+ L + C V G P+
Sbjct: 188 CGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIET 247
Query: 306 YWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
W +G L PN RI E+ L + N D+G+Y C ASN
Sbjct: 248 IWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASN 292
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 6/165 (3%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G V + C V+ P + WF E +E I ++ + L++ + D+G
Sbjct: 4361 GSSVVMECKVYGSPPISVSWFHEGNE----ISSGRKYQTTLTDNTCALTVNMLEESDSGD 4416
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN 310
+ C N GS+ L V EP S KP+ + +++ V G P V W
Sbjct: 4417 YTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKG 4476
Query: 311 GRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASNARDQA 353
L P +R + LED + L + + G Y C SN +A
Sbjct: 4477 SSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKA 4521
Score = 58.8 bits (136), Expect = 3e-08
Identities = 58/224 (25%), Positives = 99/224 (44%), Gaps = 17/224 (7%)
Query: 145 LCRVRDKITGIRTAVNTLVSH-----VIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCA 199
L +++D T + TA N S V V EP VK V+ S + G+ RL C
Sbjct: 370 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK---KVDP-SYLMLPGESARLHCK 425
Query: 200 VHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTV 259
+ PV WF + E + E+ + + E +L I V+ ED+G + C N V
Sbjct: 426 LKGSPVIQVTWFKNNKE----LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDV 481
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLHNGRTLEPNE 318
GS+S +++ EP S E ++ L C+V+G P E + W + + + ++
Sbjct: 482 GSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFE-ISWFKDKKQIRSSK 540
Query: 319 RIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYL 360
+ + + L I + + D G Y+C +N + M+ +L
Sbjct: 541 KYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHL 584
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/177 (26%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
KP E + + + V L C V T W + ++L P ++ + ++
Sbjct: 308 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWS-KDGQKLPPGKDYKICFEDKI--- 363
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV--RTKPEVLRSKPKSDIAL 293
L I + +D+G +VC +N GS S T+ V EP S + P L P L
Sbjct: 364 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYL-MLPGESARL 422
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
CK+ G P+ V W N + L + R+ + L I + +D G Y C A N
Sbjct: 423 HCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 479
Score = 57.2 bits (132), Expect = 9e-08
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 9/163 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ--KVRRED 247
VG++V+L + + WF + E + E +W E + ++Q +V +
Sbjct: 4170 VGKEVQLQTTIEGAEPISVVWFKDKGEIVR--ESDNIWIS---YSENIATLQFSRVEPAN 4224
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG++ C + N G + TL V EP ++ KPE ++ L+C V G P W
Sbjct: 4225 AGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKW 4284
Query: 308 LHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+ L + +I L I N D G+Y N
Sbjct: 4285 FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQN 4327
Score = 56.0 bits (129), Expect = 2e-07
Identities = 72/332 (21%), Positives = 128/332 (38%), Gaps = 26/332 (7%)
Query: 23 NGSLEILPFTAELYR-HDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV 81
N SLE EL+ + + Y C + + G + S H++ + + + D V
Sbjct: 3546 NISLEDFVTELELFEVQPLESGDYSCLVTNDAG--SASCTTHLFVKEPATFVKRLADFSV 3603
Query: 82 IAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRH 141
G+ +VL + S W+ D+ + + + ++ ST + +
Sbjct: 3604 ETGSPIVLEAT---YTGTPPISVSWIKDEYL-ISQSERCSITMTEKSTILEILESTIEDY 3659
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++ C + ++ + LVS V EP ++P VE +G+ L C V
Sbjct: 3660 AQYSCLIENEAG--QDICEALVS---VLEPPYFIEPLEHVEAV-----IGEPATLQCKVD 3709
Query: 202 AWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS 261
P W+ EH T + +K + L I KV D G + C +N+VG+
Sbjct: 3710 GTPEIRISWYKEH----TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGA 3765
Query: 262 ESVHFTLIVTE---PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL--EP 316
+ L++ P K + + +A +C++NG V W +G L +
Sbjct: 3766 VASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDA 3825
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + + + L I T + G Y C ASN
Sbjct: 3826 NLQTSFVHNVATLQILQTDQSHIGQYNCSASN 3857
Score = 55.6 bits (128), Expect = 3e-07
Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 7/195 (3%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A N + S K PR + +G V L V + + W + E
Sbjct: 3197 ATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEV 3256
Query: 218 LTPIEETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
+ E T R +D L + ++G+++C + N G L V EP +
Sbjct: 3257 IRESENT----RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARI 3312
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNT 334
KPE + + AL+C V G P W +GR L + + I + L I
Sbjct: 3313 IEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCA 3372
Query: 335 HKDDQGIYQCFASNA 349
D+G+Y N+
Sbjct: 3373 EMSDKGLYSFEVKNS 3387
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 10/180 (5%)
Query: 175 VKPRVSVEQ-RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
++P VE+ S ++ G L C V P + +WF + E + +K +
Sbjct: 4248 LEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKE----LTSDNKYKISFFN 4303
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---PISVRTKPEVLRSKPKSD 290
L I V D+G + + N VG +S +L V++ P S K + S
Sbjct: 4304 KVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSS 4363
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ ++CKV G P V W H G + + + + ++ L + + D G Y C A+N
Sbjct: 4364 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN 4423
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 16/224 (7%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
+ SL + V TSD + C+V + G+ + N + V EP V+ + S+
Sbjct: 925 ESSLELYLVKTSDS-GTYTCKVSNVAGGVECSAN-----LFVKEPATFVEKL----EPSQ 974
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G +L C V P WF E I+E++ + + + +L + V E
Sbjct: 975 LLKKGDATQLACKVTGTPPIKITWFANDRE----IKESSKHRMSFVESTAVLRLTDVGIE 1030
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
D+G ++C N GS+ +IV E + + + + D+ L +V G P +
Sbjct: 1031 DSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEIT 1090
Query: 307 WLHNGRTLEPNERIE-ILEDGL-RLHIKNTHKDDQGIYQCFASN 348
W + L + + ++D L L I D G YQC +N
Sbjct: 1091 WFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN 1134
Score = 55.2 bits (127), Expect = 3e-07
Identities = 75/319 (23%), Positives = 129/319 (40%), Gaps = 31/319 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVH-VPDEYVIAGNAVVLRCVVPPHCADRISS 103
Y C+ +SVG +A S + + A P+ + D + G V C + ++S
Sbjct: 3755 YSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVS- 3813
Query: 104 TEWLND-----DDINVLHYLGSKYHRLDDGSLYISAVSTSDRH-NRFLCRVRDKITGIRT 157
W D DD N+ S H + +L I + T H ++ C + + +
Sbjct: 3814 --WYKDGVLLKDDANLQT---SFVHNV--ATLQI--LQTDQSHIGQYNCSASNPLGTASS 3864
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
+ ++S V P +KP VSV+ + +G+ C V W ++ E
Sbjct: 3865 SAKLILSEHEVP-PFFDLKP-VSVD-----LALGESGTFKCHVTGTAPIKITWAKDNRE- 3916
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR 277
I +K + + L++ KV + DAG++ C+ +N G +S L V EP
Sbjct: 3917 ---IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFI 3973
Query: 278 TKPEVLRSKPKSDIA-LDCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNT 334
K E R + + +CK+ G P V W + ++ + R+ ++ L + N
Sbjct: 3974 KKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNL 4033
Query: 335 HKDDQGIYQCFASNARDQA 353
+D G Y C A NA A
Sbjct: 4034 SVEDSGDYTCEAHNAAGSA 4052
Score = 55.2 bits (127), Expect = 3e-07
Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 14/190 (7%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+ +++ EP VK V ++ VG L C + P W+ + T +
Sbjct: 4618 AQILILEPPYFVKQLEPV-----KVSVGDSASLQCQLAGTPEIGVSWY----KGDTKLRP 4668
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---PISVRTKP 280
TT +K + L +V D+G ++C N+VG S L V E P S +
Sbjct: 4669 TTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQL 4728
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDD 338
++ + DC ++G V W +G+ L+ PN + L++ L+I T +
Sbjct: 4729 RDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSL 4788
Query: 339 QGIYQCFASN 348
G Y C A+N
Sbjct: 4789 AGQYSCTATN 4798
Score = 54.8 bits (126), Expect = 5e-07
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-LDCK 296
L++ V G++ C + N VGS+S L+VTEP K E + D + L+CK
Sbjct: 2052 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECK 2111
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ G P V W N L ++ R+ ++ + + N +D G + C A N
Sbjct: 2112 IAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQN 2165
Score = 54.0 bits (124), Expect = 8e-07
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 10/158 (6%)
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
RL C + WF + E I + ++ A + L I +V DAG F C
Sbjct: 796 RLDCKIAGSLPMRVSWFKDGKE----IAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCR 851
Query: 255 LNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N+VGS+ LIV EP S TKP P S + L G + W + L
Sbjct: 852 ATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL 911
Query: 315 EPNERI----EILEDGLRLHIKNTHKDDQGIYQCFASN 348
E LE L L++ T D G Y C SN
Sbjct: 912 VSGGSCYITKEALESSLELYLVKT--SDSGTYTCKVSN 947
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 46/118 (38%), Gaps = 2/118 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L + + D G + C N GS+ L V EP S +PE L P ++ +
Sbjct: 2522 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVI 2581
Query: 298 NGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASNARDQA 353
G P V W R L +R I ED + L + N G Y C SN QA
Sbjct: 2582 RGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQA 2639
Score = 53.2 bits (122), Expect = 1e-06
Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR-SKPKSDIALDCK 296
L I KV + D+G++ C N VG + L V EP K E + +K I L+CK
Sbjct: 2993 LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECK 3052
Query: 297 VNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++G P V W N L + + + + L I +D G Y C A N
Sbjct: 3053 ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 3106
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 9/164 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG V L C V P T W+ + +L P E + + L KV D+G
Sbjct: 2757 VGDSVSLQCQVAGTPEITVSWY-KGDTKLRPTPEYRTYFTNNV---ATLVFNKVNINDSG 2812
Query: 250 RFVCWLNNTVGSESVHFTLIVTE---PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C N++G+ S + E P S + + + + L C++NG V
Sbjct: 2813 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 2872
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASN 348
W +G L +E ++ +++ L I T G Y C ASN
Sbjct: 2873 WYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASN 2916
Score = 52.0 bits (119), Expect = 3e-06
Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 15/199 (7%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
+V + + +T + + P S + R + VG V CA+ + W+ +
Sbjct: 4703 SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK-- 4760
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP---- 273
P++++ + + L + L+I K R AG++ C N +GS S LI+TE
Sbjct: 4761 --PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPP 4818
Query: 274 -ISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLHNGRTLEPNERIEI--LEDGLRL 329
+R P +D +C V G PI+ V W + R + + +I LE+ L
Sbjct: 4819 FFDIRLAPVDAVVGESAD--FECHVTGTQPIK-VSWAKDSREIRSGGKYQISYLENSAHL 4875
Query: 330 HIKNTHKDDQGIYQCFASN 348
+ K D G Y C+A N
Sbjct: 4876 TVLKVDKGDSGQYTCYAVN 4894
Score = 52.0 bits (119), Expect = 3e-06
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD---IAL 293
+L ++K DAG + C ++N GS ++++ EP + L S+ + L
Sbjct: 4971 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQL 5030
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEI-LEDGLR-LHIKNTHKDDQGIYQCFASN 348
C V G + WL GR ++P++R G L +++ K D G Y C ASN
Sbjct: 5031 SCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN 5087
Score = 51.2 bits (117), Expect = 6e-06
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 6/158 (3%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
DV L C V P W +++ ++ ++ TL R + + L I K D G +
Sbjct: 1636 DVELECEVTGTPPFEVTWL-KNNREIRSSKKYTLTDRVSVFN---LHITKCDPSDTGEYQ 1691
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C ++N GS S + + EP S K E + KS V G P + WL + +
Sbjct: 1692 CIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 1751
Query: 313 TLEPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASN 348
L+ ++ + I ++ L I++ G Y C A N
Sbjct: 1752 ILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKN 1789
Score = 51.2 bits (117), Expect = 6e-06
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I+ V +GR+ C N G E + L+V EP + K + + K + L+C V
Sbjct: 1770 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVV 1829
Query: 298 NGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIY 342
G P V WL +G+ + P+ + E+ + I++ K D G Y
Sbjct: 1830 AGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 1876
Score = 51.2 bits (117), Expect = 6e-06
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
S +++ EPK KP V +Q + V G+ V+L C V +W E + P
Sbjct: 5000 SSIVIKEPK---KPPV-FDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE-IKPS 5054
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR---- 277
+ + + +L ++ V + D+G +VC +N GS++ + + + +V
Sbjct: 5055 DRCSF---SFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATK 5111
Query: 278 -----------TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG-RTLEPNERIEILED 325
++P+ +R K+ KV G PI V W R L R+ I +
Sbjct: 5112 KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQK 5171
Query: 326 G--LRLHIKNTHKDDQGIYQCFASN 348
G +L I++T K D G+Y+C A N
Sbjct: 5172 GDEAKLEIRDTTKTDSGLYRCVAFN 5196
Score = 50.8 bits (116), Expect = 7e-06
Identities = 49/216 (22%), Positives = 85/216 (39%), Gaps = 16/216 (7%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
S++I V TSD + C+ ++++ +T V V + EP PR + S +
Sbjct: 2238 SIHILNVDTSDI-GEYHCKAQNEVGS-----DTCVCTVKLKEP-----PRFVSKLNSLTV 2286
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+ L ++ +W E E + E + + + L K +A
Sbjct: 2287 VAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI---TFVENVATLQFAKAEPANA 2343
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G+++C + N G TL+V EP + K + L+CKV G P V W
Sbjct: 2344 GKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWY 2403
Query: 309 HNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIY 342
+G+ L ++ + L I + + D G Y
Sbjct: 2404 KDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTY 2439
Score = 48.8 bits (111), Expect = 3e-05
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 6/161 (3%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG+ + C V PV W + + + W+ + ++ +L + + +D G
Sbjct: 229 VGKAAKFICTVTGTPVIETIW----QKDGAALSPSPNWRISDAENKHILELSNLTIQDRG 284
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N G++ LI+ + + E ++S + L+C+V+ V W
Sbjct: 285 VYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSK 344
Query: 310 NGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASN 348
+G+ L P + +I ED + L I D G Y C ASN
Sbjct: 345 DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 385
Score = 48.8 bits (111), Expect = 3e-05
Identities = 42/162 (25%), Positives = 63/162 (38%), Gaps = 8/162 (4%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDA 248
+G V L C V + WF + +E ++ P +++ + L+ LL D
Sbjct: 3419 LGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLE-----PSDT 3473
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G + C N GS+ L V EP S P+ + P + + G P V W
Sbjct: 3474 GIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF 3533
Query: 309 HNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASN 348
R L P E I LED + L + + G Y C +N
Sbjct: 3534 KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTN 3575
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE----PISVRTKPEVLRSKPKSDIAL 293
L++ KV + D+G++ C+ N VG +S L + E P + E + + L
Sbjct: 4875 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKL 4934
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
+ +V G V W N ++P EI + L L ++ +D G+Y C SN
Sbjct: 4935 EGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSN 4991
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/312 (22%), Positives = 115/312 (36%), Gaps = 21/312 (6%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVH-VPDEYVIAGNAVVLRCVVPPHCADRIS 102
+Y +++SVG + ++HV + P + + D I G +VVL C V
Sbjct: 3379 LYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAP---I 3435
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W D + V + +L +S + SD + C V + G L
Sbjct: 3436 SVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDT-GIYTC-VAANVAGSDECSAVL 3493
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V EP + SVE + G + + P +WF + +L P E
Sbjct: 3494 T----VQEPPSFEQTPDSVE-----VLPGMSLTFTSVIRGTPPFKVKWF-KGSRELVPGE 3543
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ + + L +Q + ++G + C + N GS S L V EP + +
Sbjct: 3544 SCNISLEDFVTELELFEVQPL---ESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLAD 3600
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNTHKDDQG 340
+ S I L+ G P V W+ + + +ER I + E L I + +D
Sbjct: 3601 FSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYA 3660
Query: 341 IYQCFASNARDQ 352
Y C N Q
Sbjct: 3661 QYSCLIENEAGQ 3672
Score = 45.2 bits (102), Expect = 4e-04
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 2/115 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I + DAG++ C + N G + + EP T+ E L + ++L C+
Sbjct: 2707 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQ 2766
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
V G P V W L P R + L + +D G Y C A N+
Sbjct: 2767 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENS 2821
Score = 44.4 bits (100), Expect = 6e-04
Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 11/182 (6%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
VK + +R+ I+V G L V P +W+ + P+ + ++ +
Sbjct: 678 VKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGR----PLVASKKYRISFK 733
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVH--FTLIVTEPISVRTKP-EVLRSKPKS 289
+ L D+G++ ++N VGS S FT++ + TKP + S
Sbjct: 734 NNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNG 793
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
LDCK+ G V W +G+ + ++ RI +E L I +D G + C A+
Sbjct: 794 TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 853
Query: 348 NA 349
N+
Sbjct: 854 NS 855
Score = 44.0 bits (99), Expect = 9e-04
Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I EDAG++ C++ N G +S +++ EP + E ++ +L C+
Sbjct: 4589 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQ 4648
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ G P V W L P ++ + L +D G Y C A N+
Sbjct: 4649 LAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENS 4703
Score = 41.5 bits (93), Expect = 0.005
Identities = 36/164 (21%), Positives = 62/164 (37%), Gaps = 6/164 (3%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ G +V V P + WF + +L P + + + + L + V
Sbjct: 4451 VLTGTNVTFTSIVKGTPPFSVSWF-KGSSELVPGDRCNVSLEDSVAE---LELFDVDTSQ 4506
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
+G + C ++N G S L + P + + + L+ G P V W
Sbjct: 4507 SGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTW 4566
Query: 308 LHNGRTLEPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASNA 349
NG + P++R I E L I ++ +D G Y C+ NA
Sbjct: 4567 KKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENA 4610
Score = 40.7 bits (91), Expect = 0.008
Identities = 33/161 (20%), Positives = 64/161 (39%), Gaps = 6/161 (3%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + + C V +P +F+ ++++ + L R + L + + ED
Sbjct: 1915 LGSSIHMECKVSG-SLPISAQWFKDGKEISTSAKYRLVCHERSVS---LEVNNLELEDTA 1970
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C ++N G ++ L V EP S KP ++ P S + + G P + W
Sbjct: 1971 NYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFK 2030
Query: 310 NGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASN 348
+ L + I +G L++ + G Y C +N
Sbjct: 2031 DDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 2071
Score = 40.3 bits (90), Expect = 0.010
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I V+ G++ C N GS++ LIV EP + + E+++ L+
Sbjct: 645 VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 704
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P W +GR L ++ RI + +L + D G Y SN
Sbjct: 705 VAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISN 758
Score = 40.3 bits (90), Expect = 0.010
Identities = 80/346 (23%), Positives = 130/346 (37%), Gaps = 38/346 (10%)
Query: 16 GLRQILKNGSL----EILPFTAELYRHDVHAT-VYRCRMRSSVGYIAMSKNIHVYAALSS 70
G ++++ GS E L + ELY + Y C++ + G + S N+ V +
Sbjct: 907 GNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATF 966
Query: 71 PWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD---- 126
++ P + + G+A L C V I T + ND +I S HR+
Sbjct: 967 VEKLE-PSQLLKKGDATQLACKVTG--TPPIKITWFANDREIKE-----SSKHRMSFVES 1018
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
L ++ V D ++C +++ + S VIV E P + E +
Sbjct: 1019 TAVLRLTDVGIEDS-GEYMCEAQNEAGSDHCS-----SIVIVKE-----SPYFTKEFKPI 1067
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ--KVR 244
+ DV L V P WF ++ T + +K + + L+S+Q K
Sbjct: 1068 EVLKEYDVMLLAEVAGTPPFEITWFKDN----TILRSGRKYKT--FIQDHLVSLQILKFV 1121
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
DAG + C + N VGS + + EP S K E S A + G
Sbjct: 1122 AADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPIT 1181
Query: 305 VYWLHNGR--TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V WL + T + N R+ + L++ G Y C A N
Sbjct: 1182 VTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 1227
Score = 39.9 bits (89), Expect = 0.014
Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L + + +G + C ++N G S L V EP + + +P I L+
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 2674
Query: 298 NGHPIELVYWLHNGRTLEPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
G V W +G + +E+ I+ E L I N+ K D G Y C N
Sbjct: 2675 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN 2727
Score = 37.9 bits (84), Expect = 0.056
Identities = 36/164 (21%), Positives = 64/164 (39%), Gaps = 13/164 (7%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS---IQKVRRED 247
G DV L C + P W+ + E + K+ +++ E L+ I V D
Sbjct: 4078 GADVHLECELQGTPPFHVSWYKDKRELRSG-------KKYKIMSENFLTSIHILNVDAAD 4130
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVY 306
G + C N VGS++ ++ + P K + + ++ L + G PI +V+
Sbjct: 4131 IGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVW 4190
Query: 307 WLHNGRTLEPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASN 348
+ G + ++ I I E+ L + G Y C N
Sbjct: 4191 FKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 4234
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L+I VR ED G++ C + S + I EPI + + + +C+V
Sbjct: 5466 LTIADVRAEDQGQYTCKYEDLETSAELR---IEAEPIQFTKRIQNIVVSEHQSATFECEV 5522
Query: 298 NGHPIELVYWLHNGRTLEPNERIEILEDGLRLH---IKNTHKDDQGIYQCFA 346
+ +V W L +++ DG R H I N DD+G+Y A
Sbjct: 5523 S-FDDAIVTWYKGPTELTESQKYNFRNDG-RCHYMTIHNVTPDDEGVYSVIA 5572
Score = 35.1 bits (77), Expect = 0.39
Identities = 35/161 (21%), Positives = 60/161 (37%), Gaps = 7/161 (4%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G DV L C + P W + + + + +K + L I + D G
Sbjct: 3137 GSDVILQCEISGTPPFEVVWVKDRKQ----VRNSKKFKITSKHFDTNLHILNLEASDVGE 3192
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLH 309
+ C N VGS++ ++ EP K + + L V G PI +V+
Sbjct: 3193 YHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKD 3252
Query: 310 NGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G + +E RI +++ L + + + G Y C N
Sbjct: 3253 RGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKN 3293
Score = 34.3 bits (75), Expect = 0.69
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 6/172 (3%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G + L C V WF + +Q+ ++ L+ + L+ L I D G
Sbjct: 510 GTNALLQCEVSGTGPFEISWF-KDKKQIRSSKKYRLFSQKSLV---CLEIFSFNSADVGE 565
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN 310
+ C + N VG T ++ EP + K + L + + L V G V W+
Sbjct: 566 YECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKG 625
Query: 311 GRTLEPNERIEI-LEDGLR-LHIKNTHKDDQGIYQCFASNARDQAYGMSEYL 360
+ + +I++ +G+ L I + G Y C A N + E +
Sbjct: 626 QEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELI 677
Score = 33.9 bits (74), Expect = 0.91
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G++VC N G + L V EP ++ + + L K +G W
Sbjct: 1219 GKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWF 1278
Query: 309 HNGR--TLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
+G+ TL +I + + L I +T K D G Y
Sbjct: 1279 KDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEY 1314
Score = 33.5 bits (73), Expect = 1.2
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
C+V+G ++ V W + ++P+ R+ ED +L I + +D+G Y A+NA Q
Sbjct: 31 CRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQ 89
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 77.8 bits (183), Expect = 6e-14
Identities = 48/185 (25%), Positives = 85/185 (45%), Gaps = 10/185 (5%)
Query: 166 VIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT 225
++VTEP VK + S+ ++ G RL C + P WF HE + +
Sbjct: 6344 LLVTEPPKFVKKL----EASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHE----LPASD 6395
Query: 226 LWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
++ + ++ + + ED+G F+C N GS S +IV EP + P ++ +
Sbjct: 6396 KYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVET 6455
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQ 343
++++L+C+++G P V W + R L +++ +I +HI N D G Y
Sbjct: 6456 LKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYH 6515
Query: 344 CFASN 348
C A N
Sbjct: 6516 CKAQN 6520
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/187 (26%), Positives = 89/187 (47%), Gaps = 10/187 (5%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+H+ V EP +K + SR ++ + R C + P W+ + T I+E
Sbjct: 8224 AHLGVQEPPRFIKKL----EPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE----TEIQE 8275
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
++ ++ + + +L + + ED+G + C +N GS S +L V EP R KP +
Sbjct: 8276 SSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPI 8335
Query: 284 RSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGI 341
+ +D+ L+C++ G P V W + R L ++ +I+ + +HI N D G
Sbjct: 8336 ETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGE 8395
Query: 342 YQCFASN 348
YQC A+N
Sbjct: 8396 YQCKATN 8402
Score = 72.9 bits (171), Expect = 2e-12
Identities = 44/168 (26%), Positives = 77/168 (45%), Gaps = 6/168 (3%)
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
+ S+ + G+ ++L C + P WF E + E+ + + + LL+I +
Sbjct: 7298 EASKVAKQGESIQLECKISGSPEIKVSWFRNDSE----LHESWKYNMSFINSVALLTINE 7353
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPI 302
ED+G ++C +N VG S L V P KP + + SD+ L C+++G P
Sbjct: 7354 ASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPP 7413
Query: 303 ELVYWLHNGRTLEPNERIEILED--GLRLHIKNTHKDDQGIYQCFASN 348
V W+ + + + +++ +I LHI N D G Y C A+N
Sbjct: 7414 FEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATN 7461
Score = 69.3 bits (162), Expect = 2e-11
Identities = 80/311 (25%), Positives = 128/311 (41%), Gaps = 31/311 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNA-VVLRCVVPPHCADRISS 103
Y C + G+ S ++ V P+ V P + N V L+ +V I
Sbjct: 5672 YTCSATNKAGHNQCSGHLTVK---EPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTI-- 5726
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
+W D+ LH ++ DD S L + A +D ++C++ + + G T+ T
Sbjct: 5727 -KWFKDN--KELHSGAARSVWKDDTSTSLELFAAKATDS-GTYICQLSNDV-GTATSKAT 5781
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
L V EP +K V +R GQ C + P W+ + +E +T I
Sbjct: 5782 L----FVKEPPQFIKKPSPVLV----LRNGQSTTFECQITGTPKIRVSWYLDGNE-ITAI 5832
Query: 222 EETTLWKRARLLDEGLLSIQ--KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK 279
+ K +GL + Q R E++G +VC N G+ S L V EP + +
Sbjct: 5833 Q-----KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRE 5887
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILE--DGLRLHIKNTHKD 337
+ + SD+ L+C+V G P V WL N R + +++ + + LHI
Sbjct: 5888 LKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPS 5947
Query: 338 DQGIYQCFASN 348
D G YQC SN
Sbjct: 5948 DTGEYQCIVSN 5958
Score = 63.3 bits (147), Expect = 1e-09
Identities = 63/260 (24%), Positives = 114/260 (43%), Gaps = 19/260 (7%)
Query: 96 HCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLY---ISAVSTSDRHNRFLCRVRDKI 152
H I++ + +N N L K+ L D + Y I V+T D ++C +
Sbjct: 4307 HLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALND- 4365
Query: 153 TGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFF 212
+G +TA + ++ V P +K ++ + + +G + C + + P ++WF
Sbjct: 4366 SG-KTATSAKLTVVKRAAPV--IKRKIEPLE----VALGHLAKFTCEIQSAPNVRFQWFK 4418
Query: 213 EHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
E + ++ ++ + ++ + L I + + D G + C +N GS S TL VTE
Sbjct: 4419 AGRE-IYESDKCSI-RSSKYISS--LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE 4474
Query: 273 --PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLR 328
P + ++P+ L + C V G P+ W +G L PN +I E+
Sbjct: 4475 AYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHI 4534
Query: 329 LHIKNTHKDDQGIYQCFASN 348
L + N D+G+Y C ASN
Sbjct: 4535 LELSNLTIQDRGVYSCKASN 4554
Score = 61.7 bits (143), Expect = 4e-09
Identities = 73/309 (23%), Positives = 122/309 (39%), Gaps = 24/309 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
Y +++ VG + I+V + P + + I G+ + L C+V S
Sbjct: 5576 YTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIV---AGSHPIS 5632
Query: 104 TEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
+W DD +I+ +H + L IS + +D + C +K N
Sbjct: 5633 IQWFKDDQEISASEKYKFSFHD-NTAFLEISQLEGTDS-GTYTCSATNK-----AGHNQC 5685
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
H+ V EP P + +S+ + V+L V T +WF ++ E L
Sbjct: 5686 SGHLTVKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE-LHSGA 5739
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE- 281
++WK L + + D+G ++C L+N VG+ + TL V EP KP
Sbjct: 5740 ARSVWKDDTSTS---LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSP 5796
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQ 339
VL + +C++ G P V W +G + ++ I DGL I ++
Sbjct: 5797 VLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENS 5856
Query: 340 GIYQCFASN 348
G Y C A N
Sbjct: 5857 GTYVCEARN 5865
Score = 60.9 bits (141), Expect = 7e-09
Identities = 61/223 (27%), Positives = 91/223 (40%), Gaps = 18/223 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
SL I V +D N F CR + + G + + L IV EP P + S+ +
Sbjct: 5096 SLEIIRVDMNDAGN-FTCRATNSV-GSKDSSGAL----IVQEP-----PSFVTKPGSKDV 5144
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G V L T RWF + +++L + K A E L + V+ D+
Sbjct: 5145 LPGSAVCLKSTFQGSTPLTIRWF-KGNKELVSGGSCYITKEAL---ESSLELYLVKTSDS 5200
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-LDCKVNGHPIELVYW 307
G + C ++N G L V EP + K E + K D L CKV G P + W
Sbjct: 5201 GTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITW 5260
Query: 308 LHNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N R ++ + R+ +E L + + +D G Y C A N
Sbjct: 5261 FANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQN 5303
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 6/165 (3%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G V + C V+ P + WF E +E I ++ + L++ + D+G
Sbjct: 8623 GSSVVMECKVYGSPPISVSWFHEGNE----ISSGRKYQTTLTDNTCALTVNMLEESDSGD 8678
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN 310
+ C N GS+ L V EP S KP+ + +++ V G P V W
Sbjct: 8679 YTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKG 8738
Query: 311 GRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASNARDQA 353
L P +R + LED + L + + G Y C SN +A
Sbjct: 8739 SSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKA 8783
Score = 58.8 bits (136), Expect = 3e-08
Identities = 58/224 (25%), Positives = 99/224 (44%), Gaps = 17/224 (7%)
Query: 145 LCRVRDKITGIRTAVNTLVSH-----VIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCA 199
L +++D T + TA N S V V EP VK V+ S + G+ RL C
Sbjct: 4632 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK---KVDP-SYLMLPGESARLHCK 4687
Query: 200 VHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTV 259
+ PV WF + E + E+ + + E +L I V+ ED+G + C N V
Sbjct: 4688 LKGSPVIQVTWFKNNKE----LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDV 4743
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLHNGRTLEPNE 318
GS+S +++ EP S E ++ L C+V+G P E + W + + + ++
Sbjct: 4744 GSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFE-ISWFKDKKQIRSSK 4802
Query: 319 RIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYL 360
+ + + L I + + D G Y+C +N + M+ +L
Sbjct: 4803 KYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHL 4846
Score = 58.4 bits (135), Expect = 4e-08
Identities = 73/332 (21%), Positives = 129/332 (38%), Gaps = 26/332 (7%)
Query: 23 NGSLEILPFTAELYR-HDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV 81
N SLE EL+ + + Y C + + G + S H++ + + + D V
Sbjct: 7808 NISLEDFVTELELFEVQPLESGDYSCLVTNDAG--SASCTTHLFVKEPATFVKRLADFSV 7865
Query: 82 IAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRH 141
G+ +VL + S W+ D+ + + + ++ ST + +
Sbjct: 7866 ETGSPIVLEAT---YTGTPPISVSWIKDEYL-ISQSERCSITMTEKSTILEILESTIEDY 7921
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++ C + ++ + LVS V EP ++P VE +G+ L C V
Sbjct: 7922 AQYSCLIENEAG--QDICEALVS---VLEPPYFIEPLEHVEAV-----IGEPATLQCKVD 7971
Query: 202 AWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGS 261
P W+ EH T + +K + L I KV D G + C +N+VG+
Sbjct: 7972 GTPEIRISWYKEH----TKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGA 8027
Query: 262 ESVHFTLIVTE---PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL--EP 316
+ L++ E P K + + +A +C++NG V W +G L +
Sbjct: 8028 VASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDA 8087
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + + + L I T + G Y C ASN
Sbjct: 8088 NLQTSFVHNVATLQILQTDQSHIGQYNCSASN 8119
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/177 (26%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
KP E + + + V L C V T W + ++L P ++ + ++
Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWS-KDGQKLPPGKDYKICFEDKI--- 4625
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV--RTKPEVLRSKPKSDIAL 293
L I + +D+G +VC +N GS S T+ V EP S + P L P L
Sbjct: 4626 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYL-MLPGESARL 4684
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
CK+ G P+ V W N + L + R+ + L I + +D G Y C A N
Sbjct: 4685 HCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVN 4741
Score = 57.2 bits (132), Expect = 9e-08
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 9/163 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ--KVRRED 247
VG++V+L + + WF + E + E +W E + ++Q +V +
Sbjct: 8432 VGKEVQLQTTIEGAEPISVVWFKDKGEIVR--ESDNIWIS---YSENIATLQFSRVEPAN 8486
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG++ C + N G + TL V EP ++ KPE ++ L+C V G P W
Sbjct: 8487 AGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKW 8546
Query: 308 LHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+ L + +I L I N D G+Y N
Sbjct: 8547 FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQN 8589
Score = 55.6 bits (128), Expect = 3e-07
Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 7/195 (3%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A N + S K PR + +G V L V + + W + E
Sbjct: 7459 ATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEV 7518
Query: 218 LTPIEETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISV 276
+ E T R +D L + ++G+++C + N G L V EP +
Sbjct: 7519 IRESENT----RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARI 7574
Query: 277 RTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNT 334
KPE + + AL+C V G P W +GR L + + I + L I
Sbjct: 7575 IEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCA 7634
Query: 335 HKDDQGIYQCFASNA 349
D+G+Y N+
Sbjct: 7635 EMSDKGLYSFEVKNS 7649
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/180 (24%), Positives = 75/180 (41%), Gaps = 10/180 (5%)
Query: 175 VKPRVSVEQ-RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
++P VE+ S ++ G L C V P + +WF + E + +K +
Sbjct: 8510 LEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKE----LTSDNKYKISFFN 8565
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---PISVRTKPEVLRSKPKSD 290
L I V D+G + + N VG +S +L V++ P S K + S
Sbjct: 8566 KVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSS 8625
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ ++CKV G P V W H G + + + + ++ L + + D G Y C A+N
Sbjct: 8626 VVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN 8685
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 16/224 (7%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
+ SL + V TSD + C+V + G+ + N + V EP V+ + S+
Sbjct: 5187 ESSLELYLVKTSDS-GTYTCKVSNVAGGVECSAN-----LFVKEPATFVEKL----EPSQ 5236
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G +L C V P WF E I+E++ + + + +L + V E
Sbjct: 5237 LLKKGDATQLACKVTGTPPIKITWFANDRE----IKESSKHRMSFVESTAVLRLTDVGIE 5292
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
D+G ++C N GS+ +IV E + + + + D+ L +V G P +
Sbjct: 5293 DSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEIT 5352
Query: 307 WLHNGRTLEPNERIE-ILEDGL-RLHIKNTHKDDQGIYQCFASN 348
W + L + + ++D L L I D G YQC +N
Sbjct: 5353 WFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTN 5396
Score = 55.2 bits (127), Expect = 3e-07
Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 14/190 (7%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+ +++ EP VK V ++ VG L C + P W+ + T +
Sbjct: 8880 AQILILEPPYFVKQLEPV-----KVSVGDSASLQCQLAGTPEIGVSWY----KGDTKLRP 8930
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---PISVRTKP 280
TT +K + L +V D+G ++C N+VG S L V E P S +
Sbjct: 8931 TTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQL 8990
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDD 338
++ + DC ++G V W +G+ L+ PN + L++ L+I T +
Sbjct: 8991 RDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSL 9050
Query: 339 QGIYQCFASN 348
G Y C A+N
Sbjct: 9051 AGQYSCTATN 9060
Score = 54.8 bits (126), Expect = 5e-07
Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-LDCK 296
L++ V G++ C + N VGS+S L+VTEP K E + D + L+CK
Sbjct: 6314 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECK 6373
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ G P V W N L ++ R+ ++ + + N +D G + C A N
Sbjct: 6374 IAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQN 6427
Score = 54.4 bits (125), Expect = 6e-07
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 3/130 (2%)
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSK 286
+K + + L++ KV + DAG++ C+ +N G +S L V EP K E R
Sbjct: 8185 YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEPSRIV 8244
Query: 287 PKSDIA-LDCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQ 343
+ + +CK+ G P V W + ++ + R+ ++ L + N +D G Y
Sbjct: 8245 KQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYT 8304
Query: 344 CFASNARDQA 353
C A NA A
Sbjct: 8305 CEAHNAAGSA 8314
Score = 54.0 bits (124), Expect = 8e-07
Identities = 47/158 (29%), Positives = 61/158 (38%), Gaps = 10/158 (6%)
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
RL C + WF + E I + ++ A + L I +V DAG F C
Sbjct: 5058 RLDCKIAGSLPMRVSWFKDGKE----IAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCR 5113
Query: 255 LNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N+VGS+ LIV EP S TKP P S + L G + W + L
Sbjct: 5114 ATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL 5173
Query: 315 EPNERI----EILEDGLRLHIKNTHKDDQGIYQCFASN 348
E LE L L++ T D G Y C SN
Sbjct: 5174 VSGGSCYITKEALESSLELYLVKT--SDSGTYTCKVSN 5209
Score = 54.0 bits (124), Expect = 8e-07
Identities = 35/118 (29%), Positives = 46/118 (38%), Gaps = 2/118 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L + + D G + C N GS+ L V EP S +PE L P ++ +
Sbjct: 6784 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVI 6843
Query: 298 NGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASNARDQA 353
G P V W R L +R I ED + L + N G Y C SN QA
Sbjct: 6844 RGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQA 6901
Score = 53.2 bits (122), Expect = 1e-06
Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR-SKPKSDIALDCK 296
L I KV + D+G++ C N VG + L V EP K E + +K I L+CK
Sbjct: 7255 LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECK 7314
Query: 297 VNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++G P V W N L + + + + L I +D G Y C A N
Sbjct: 7315 ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHN 7368
Score = 52.8 bits (121), Expect = 2e-06
Identities = 50/216 (23%), Positives = 86/216 (39%), Gaps = 16/216 (7%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
S++I V TSD + C+ ++++ +T V V + EP PR + S +
Sbjct: 6500 SIHILNVDTSDI-GEYHCKAQNEVGS-----DTCVCTVKLKEP-----PRFVSKLNSLTV 6548
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+ L ++ +W E E + E + + + L K +A
Sbjct: 6549 VAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI---TFVENVATLQFAKAEPANA 6605
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G+++C + N G E TL+V EP + K + L+CKV G P V W
Sbjct: 6606 GKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWY 6665
Query: 309 HNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIY 342
+G+ L ++ + L I + + D G Y
Sbjct: 6666 KDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTY 6701
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 9/164 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG V L C V P T W+ + +L P E + + L KV D+G
Sbjct: 7019 VGDSVSLQCQVAGTPEITVSWY-KGDTKLRPTPEYRTYFTNNV---ATLVFNKVNINDSG 7074
Query: 250 RFVCWLNNTVGSESVHFTLIVTE---PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C N++G+ S + E P S + + + + L C++NG V
Sbjct: 7075 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 7134
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASN 348
W +G L +E ++ +++ L I T G Y C ASN
Sbjct: 7135 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASN 7178
Score = 52.0 bits (119), Expect = 3e-06
Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 15/199 (7%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
+V + + +T + + P S + R + VG V CA+ + W+ +
Sbjct: 8965 SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK-- 9022
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP---- 273
P++++ + + L + L+I K R AG++ C N +GS S LI+TE
Sbjct: 9023 --PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPP 9080
Query: 274 -ISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLHNGRTLEPNERIEI--LEDGLRL 329
+R P +D +C V G PI+ V W + R + + +I LE+ L
Sbjct: 9081 FFDIRLAPVDAVVGESAD--FECHVTGTQPIK-VSWAKDSREIRSGGKYQISYLENSAHL 9137
Query: 330 HIKNTHKDDQGIYQCFASN 348
+ K D G Y C+A N
Sbjct: 9138 TVLKVDKGDSGQYTCYAVN 9156
Score = 52.0 bits (119), Expect = 3e-06
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD---IAL 293
+L ++K DAG + C ++N GS ++++ EP + L S+ + L
Sbjct: 9233 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQL 9292
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEI-LEDGLR-LHIKNTHKDDQGIYQCFASN 348
C V G + WL GR ++P++R G L +++ K D G Y C ASN
Sbjct: 9293 SCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN 9349
Score = 51.2 bits (117), Expect = 6e-06
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 6/158 (3%)
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
DV L C V P W +++ ++ ++ TL R + + L I K D G +
Sbjct: 5898 DVELECEVTGTPPFEVTWL-KNNREIRSSKKYTLTDRVSVFN---LHITKCDPSDTGEYQ 5953
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C ++N GS S + + EP S K E + KS V G P + WL + +
Sbjct: 5954 CIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 6013
Query: 313 TLEPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASN 348
L+ ++ + I ++ L I++ G Y C A N
Sbjct: 6014 ILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKN 6051
Score = 51.2 bits (117), Expect = 6e-06
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I+ V +GR+ C N G E + L+V EP + K + + K + L+C V
Sbjct: 6032 LQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVV 6091
Query: 298 NGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIY 342
G P V WL +G+ + P+ + E+ + I++ K D G Y
Sbjct: 6092 AGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQY 6138
Score = 51.2 bits (117), Expect = 6e-06
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
S +++ EPK KP V +Q + V G+ V+L C V +W E + P
Sbjct: 9262 SSIVIKEPK---KPPV-FDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE-IKPS 9316
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR---- 277
+ + + +L ++ V + D+G +VC +N GS++ + + + +V
Sbjct: 9317 DRCSF---SFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATK 9373
Query: 278 -----------TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG-RTLEPNERIEILED 325
++P+ +R K+ KV G PI V W R L R+ I +
Sbjct: 9374 KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQK 9433
Query: 326 G--LRLHIKNTHKDDQGIYQCFASN 348
G +L I++T K D G+Y+C A N
Sbjct: 9434 GDEAKLEIRDTTKTDSGLYRCVAFN 9458
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 6/161 (3%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG+ + C V PV W + + + WK + ++ +L + + +D G
Sbjct: 4491 VGKAAKFICTVTGTPVIETIW----QKDGAALSPSPNWKISDAENKHILELSNLTIQDRG 4546
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C +N G++ LI+ + + E ++S + L+C+V+ V W
Sbjct: 4547 VYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSK 4606
Query: 310 NGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASN 348
+G+ L P + +I ED + L I D G Y C ASN
Sbjct: 4607 DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 4647
Score = 48.8 bits (111), Expect = 3e-05
Identities = 42/162 (25%), Positives = 63/162 (38%), Gaps = 8/162 (4%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDA 248
+G V L C V + WF + +E ++ P +++ + L+ LL D
Sbjct: 7681 LGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLE-----PSDT 7735
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G + C N GS+ L V EP S P+ + P + + G P V W
Sbjct: 7736 GIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF 7795
Query: 309 HNGRTLEPNERIEI-LEDGL-RLHIKNTHKDDQGIYQCFASN 348
R L P E I LED + L + + G Y C +N
Sbjct: 7796 KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTN 7837
Score = 48.4 bits (110), Expect = 4e-05
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 6/117 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE----PISVRTKPEVLRSKPKSDIAL 293
L++ KV + D+G++ C+ N VG +S L + E P + E + + L
Sbjct: 9137 LTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKL 9196
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
+ +V G V W N ++P EI + L L ++ +D G+Y C SN
Sbjct: 9197 EGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSN 9253
Score = 46.8 bits (106), Expect = 1e-04
Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNER--IEILEDG-LRLHIKNTHKDDQGIYQCFAS 347
+ CK++G+P+ + W +G+ ++ ER ++ L+DG L I +D+GIY FAS
Sbjct: 1308 VTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFAS 1367
Query: 348 NARDQA 353
N + A
Sbjct: 1368 NIKGNA 1373
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 9/138 (6%)
Query: 222 EETTLWKRARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
EE R +L EG +L IQ EDAG + C L ++ V + E IS
Sbjct: 13427 EEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQ 13486
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHK 336
E+L + K++ P++ W + +TLE ++ +++ DG + L +K+
Sbjct: 13487 NLEILEGE-KAEFVCSISKESFPVQ---WKRDDKTLESGDKYDVIADGKKRVLVVKDATL 13542
Query: 337 DDQGIYQCFASNARDQAY 354
D G Y AR A+
Sbjct: 13543 QDMGTYVVMVGAARAAAH 13560
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/312 (22%), Positives = 115/312 (36%), Gaps = 21/312 (6%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVH-VPDEYVIAGNAVVLRCVVPPHCADRIS 102
+Y +++SVG + ++HV + P + + D I G +VVL C V
Sbjct: 7641 LYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAP---I 7697
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W D + V + +L +S + SD + C V + G L
Sbjct: 7698 SVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDT-GIYTC-VAANVAGSDECSAVL 7755
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V EP + SVE + G + + P +WF + +L P E
Sbjct: 7756 T----VQEPPSFEQTPDSVE-----VLPGMSLTFTSVIRGTPPFKVKWF-KGSRELVPGE 7805
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ + + L +Q + ++G + C + N GS S L V EP + +
Sbjct: 7806 SCNISLEDFVTELELFEVQPL---ESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLAD 7862
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNER--IEILEDGLRLHIKNTHKDDQG 340
+ S I L+ G P V W+ + + +ER I + E L I + +D
Sbjct: 7863 FSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYA 7922
Query: 341 IYQCFASNARDQ 352
Y C N Q
Sbjct: 7923 QYSCLIENEAGQ 7934
Score = 45.2 bits (102), Expect = 4e-04
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 2/115 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I + DAG++ C + N G + + EP T+ E L + ++L C+
Sbjct: 6969 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQ 7028
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
V G P V W L P R + L + +D G Y C A N+
Sbjct: 7029 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENS 7083
Score = 44.8 bits (101), Expect = 5e-04
Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 10/117 (8%)
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
R+ +V+ +V EP VKP S S ++VGQD+++ + P PT W +
Sbjct: 24142 RSLAVPIVAKDLVIEPD--VKPAFS----SYSVQVGQDLKIEVPISGRPKPTITWTKDG- 24194
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P+++TT LD LSI++ ++D G++ + N VG ++ ++ +
Sbjct: 24195 ---LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLD 24248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 11/182 (6%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
VK + +R+ I+V G L V P +W+ + P+ + ++ +
Sbjct: 4940 VKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGR----PLVASKKYRISFK 4995
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVH--FTLIVTEPISVRTKP-EVLRSKPKS 289
+ L D+G++ ++N VGS S FT++ + TKP + S
Sbjct: 4996 NNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNG 5055
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
LDCK+ G V W +G+ + ++ RI +E L I +D G + C A+
Sbjct: 5056 TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 5115
Query: 348 NA 349
N+
Sbjct: 5116 NS 5117
Score = 44.0 bits (99), Expect = 9e-04
Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I EDAG++ C++ N G +S +++ EP + E ++ +L C+
Sbjct: 8851 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQ 8910
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ G P V W L P ++ + L +D G Y C A N+
Sbjct: 8911 LAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENS 8965
Score = 42.7 bits (96), Expect = 0.002
Identities = 41/180 (22%), Positives = 75/180 (41%), Gaps = 11/180 (6%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL--LSIQKVRREDA 248
G + +PVP WF + I +TL +G L+I V + ++
Sbjct: 20 GSTATFEAHISGFPVPEVSWFRDGQV----ISTSTLPGVQISFSDGRAKLTIPAVTKANS 75
Query: 249 GRFVCWLNNTVGSESVHFTLIV---TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
GR+ N G + L+V T P + + + + + S + L +V G P +V
Sbjct: 76 GRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVV 135
Query: 306 YWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
+ +G ++ + +I ++G L I + +D G Y A+N+ +A +E L G
Sbjct: 136 KFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 42.3 bits (95), Expect = 0.003
Identities = 56/229 (24%), Positives = 88/229 (38%), Gaps = 24/229 (10%)
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
H F+ R G T V + P+V E + ++ G+ R +
Sbjct: 3203 HRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVI 3262
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD--EGLLSIQKVRREDAGRFVCWLNNT 258
P P W+ E EQL +T +K L D E L + + EDA + C N
Sbjct: 3263 SGRPQPKISWYKE--EQLL----STGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKND 3316
Query: 259 VGSESVHFTLIVTEPISVRTKPEV----------LRSKPKSD---IALDCKVNGHPIELV 305
G + +L V P V E+ L+ S+ C+V+G ++ V
Sbjct: 3317 YGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLK-V 3375
Query: 306 YWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
W + ++P+ R+ ED +L I + +D+G Y ASNA Q
Sbjct: 3376 SWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ 3424
Score = 42.3 bits (95), Expect = 0.003
Identities = 36/164 (21%), Positives = 62/164 (37%), Gaps = 6/164 (3%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ G +V V P + WF + +L P + + + + L + V
Sbjct: 8713 VLTGTNVTFTSIVKGTPPFSVSWF-KGSSELVPGDRCNVSLEDSVAE---LELFDVDTSQ 8768
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
+G + C ++N G S L + P + + + L+ G P V W
Sbjct: 8769 SGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTW 8828
Query: 308 LHNGRTLEPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASNA 349
NG + P++R I E L I ++ +D G Y C+ NA
Sbjct: 8829 KKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENA 8872
Score = 42.3 bits (95), Expect = 0.003
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 5/131 (3%)
Query: 135 VSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK--GGVKPRVSVEQRSRRIRVGQ 192
V D H + RV+ + I + +L +V++ + + +K R+SV + +++ G+
Sbjct: 16283 VENLDEHQMYEFRVK-AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGE 16341
Query: 193 DVRLPCAVHAWPVPTYRWFFEHH--EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
V +P V P+P W E+ T + T + +R + LSI K RED G
Sbjct: 16342 PVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT 16401
Query: 251 FVCWLNNTVGS 261
+ +N +GS
Sbjct: 16402 YTVTASNRLGS 16412
Score = 42.3 bits (95), Expect = 0.003
Identities = 45/222 (20%), Positives = 88/222 (39%), Gaps = 11/222 (4%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
+R + VG SKN Y A P+ ++ N + L+ P + + +
Sbjct: 24422 FRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITG 24481
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ D+ ++ + + + + +S + T D+ F ++ I ++
Sbjct: 24482 YIVEKRDLPDGRWMKASFTNVIETQFTVSGL-TEDQRYEFRVIAKNAAGAISKPSDSTGP 24540
Query: 165 HVIVTEPKGGVKPRVSVEQRSRR---IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+T PR+S++ + R + G+ RL VH P+PT W E I
Sbjct: 24541 ---ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKE----I 24593
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
EE+ + + LL ++ R D G+++ +N GS+S
Sbjct: 24594 EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 24635
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I+ + +EDAG + + S S ++ + I+ V+ + L+CK
Sbjct: 2411 MLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEG---TKAVLECK 2467
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQ 343
V+ + V W N ++P++R++ + G RL I TH D+G Y+
Sbjct: 2468 VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYK 2516
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 13/120 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKS-DIALD-- 294
L I + + G++ C +N +G+ S LI++E P KP S D+AL
Sbjct: 8100 LQILQTDQSHIGQYNCSASNPLGTASSSAKLILSE----HEVPPFFDLKPVSVDLALGES 8155
Query: 295 ----CKVNGHPIELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C V G + W + R + P N ++ ++E+ L + K D G Y C+ASN
Sbjct: 8156 GTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASN 8215
Score = 40.7 bits (91), Expect = 0.008
Identities = 33/161 (20%), Positives = 64/161 (39%), Gaps = 6/161 (3%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + + C V +P +F+ ++++ + L R + L + + ED
Sbjct: 6177 LGSSIHMECKVSG-SLPISAQWFKDGKEISTSAKYRLVCHERSVS---LEVNNLELEDTA 6232
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C ++N G ++ L V EP S KP ++ P S + + G P + W
Sbjct: 6233 NYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFK 6292
Query: 310 NGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASN 348
+ L + I +G L++ + G Y C +N
Sbjct: 6293 DDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333
Score = 40.7 bits (91), Expect = 0.008
Identities = 45/180 (25%), Positives = 78/180 (43%), Gaps = 16/180 (8%)
Query: 175 VKPRVSVEQRSRR---IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRAR 231
VKPRV R + + G+ C + +P W+ + ++L P ++ +
Sbjct: 13118 VKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPV-EWYLKG-KKLEPSDKVVPRSEGK 13175
Query: 232 LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP-EVLRSKPKSD 290
+ L+++ V+ EDAG + T H L V EP TKP E + +
Sbjct: 13176 V---HTLTLRDVKLEDAGE----VQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGAT 13228
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASN 348
L+C+V+ + V W NG + +++ EI+ DG +L I + +D Y C A +
Sbjct: 13229 AVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 13287
Score = 40.7 bits (91), Expect = 0.008
Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 9/117 (7%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
++ G +RL V P P W + + T + + K D S+ K +R D
Sbjct: 19140 VKAGDTIRLEAGVRGKPFPEVAWTKD--KDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 19197
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD-CKVNGHPIE 303
G++V NT GS + T ++V KP +R+ D++ D C V P E
Sbjct: 19198 GGKYVVTATNTAGSFVAYAT------VNVLDKPGPVRNLKIVDVSSDRCTVCWDPPE 19248
Score = 40.7 bits (91), Expect = 0.008
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILE--DGLRLHIKNTHKDDQGIYQCFAS 347
D+ ++ ++G P + W +G L+ RI + + D L IK THKDD G Y +
Sbjct: 24173 DLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 24232
Query: 348 NARDQ 352
N Q
Sbjct: 24233 NVVGQ 24237
Score = 40.3 bits (90), Expect = 0.010
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L I V+ G++ C N GS++ LIV EP + + E+++ L+
Sbjct: 4907 VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 4966
Query: 297 VNGHPIELVYWLHNGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G P W +GR L ++ RI + +L + D G Y SN
Sbjct: 4967 VAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISN 5020
Score = 40.3 bits (90), Expect = 0.010
Identities = 80/346 (23%), Positives = 130/346 (37%), Gaps = 38/346 (10%)
Query: 16 GLRQILKNGSL----EILPFTAELYRHDVHAT-VYRCRMRSSVGYIAMSKNIHVYAALSS 70
G ++++ GS E L + ELY + Y C++ + G + S N+ V +
Sbjct: 5169 GNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATF 5228
Query: 71 PWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD---- 126
++ P + + G+A L C V I T + ND +I S HR+
Sbjct: 5229 VEKLE-PSQLLKKGDATQLACKVTG--TPPIKITWFANDREIKE-----SSKHRMSFVES 5280
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR 186
L ++ V D ++C +++ + S VIV E P + E +
Sbjct: 5281 TAVLRLTDVGIEDS-GEYMCEAQNEAGSDHCS-----SIVIVKE-----SPYFTKEFKPI 5329
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ--KVR 244
+ DV L V P WF ++ T + +K + + L+S+Q K
Sbjct: 5330 EVLKEYDVMLLAEVAGTPPFEITWFKDN----TILRSGRKYKT--FIQDHLVSLQILKFV 5383
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
DAG + C + N VGS + + EP S K E S A + G
Sbjct: 5384 AADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPIT 5443
Query: 305 VYWLHNGR--TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V WL + T + N R+ + L++ G Y C A N
Sbjct: 5444 VTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKN 5489
Score = 39.9 bits (89), Expect = 0.014
Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 2/113 (1%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L + + +G + C ++N G S L V EP + + +P I L+
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 6936
Query: 298 NGHPIELVYWLHNGRTLEPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
G V W +G + +E+ I+ E L I N+ K D G Y C N
Sbjct: 6937 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN 6989
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ G+D+++ P P W H+ P+++TT + LL+I+ RED
Sbjct: 23086 VLAGEDLKVDVPFIGRPTPAVTW----HKDNVPLKQTTRVNAESTENNSLLTIKDACRED 23141
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
G +V L N+ G +IV + T P
Sbjct: 23142 VGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGP 23174
Score = 39.1 bits (87), Expect = 0.024
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFAS 347
D+ ++ V G P + W+ +G L+ R+ + E LHIK +KDD G Y A+
Sbjct: 25255 DLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTAT 25314
Query: 348 NARDQA 353
N+ A
Sbjct: 25315 NSAGTA 25320
Score = 38.3 bits (85), Expect = 0.042
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G+ V L C + +P PT W+ E ++ IE + ++ L I++ ED+GR
Sbjct: 957 GESVTLECHISGYPSPTVTWYREDYQ----IESSIDFQITFQSGIARLMIREAFAEDSGR 1012
Query: 251 FVCWLNNTVGSESVHFTLIV 270
F C N G+ S L V
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAV 1032
Score = 38.3 bits (85), Expect = 0.042
Identities = 44/183 (24%), Positives = 69/183 (37%), Gaps = 14/183 (7%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
KP ++ S + GQ R V P+P WF + + + + K
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQS- 1514
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP---EVLRS---KPKS 289
L I D+G + N G S+ L V E + + KP E L++ K S
Sbjct: 1515 --LIIVPATPSDSGEWTVVAQNRAGRSSISVILTV-EAVEHQVKPMFVEKLKNVNIKEGS 1571
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNE----RIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ + + G+P + WL N + P++ RIE + L I +T D Y
Sbjct: 1572 QLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1631
Query: 346 ASN 348
A N
Sbjct: 1632 AIN 1634
Score = 37.9 bits (84), Expect = 0.056
Identities = 36/164 (21%), Positives = 64/164 (39%), Gaps = 13/164 (7%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS---IQKVRRED 247
G DV L C + P W+ + E + K+ +++ E L+ I V D
Sbjct: 8340 GADVHLECELQGTPPFHVSWYKDKRELRSG-------KKYKIMSENFLTSIHILNVDAAD 8392
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVY 306
G + C N VGS++ ++ + P K + + ++ L + G PI +V+
Sbjct: 8393 IGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVW 8452
Query: 307 WLHNGRTLEPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASN 348
+ G + ++ I I E+ L + G Y C N
Sbjct: 8453 FKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 8496
Score = 37.5 bits (83), Expect = 0.074
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 4/93 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
++ G VR P + PVPT +W + E T T +L+I+ R D
Sbjct: 18449 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF----SSVLTIKNCLRRD 18504
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
G + ++N GS++V L V + T P
Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGP 18537
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L+I VR ED G++ C + S + I EPI + + + +C+V
Sbjct: 9728 LTIADVRAEDQGQYTCKYEDLETSAELR---IEAEPIQFTKRIQNIVVSEHQSATFECEV 9784
Query: 298 NGHPIELVYWLHNGRTLEPNERIEILEDGLRLH---IKNTHKDDQGIYQCFA 346
+ +V W L +++ DG R H I N DD+G+Y A
Sbjct: 9785 S-FDDAIVTWYKGPTELTESQKYNFRNDG-RCHYMTIHNVTPDDEGVYSVIA 9834
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 7/118 (5%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
+L ++ +D G +V + + H T+I I V K R K + ++ +C+
Sbjct: 13534 VLVVKDATLQDMGTYVVMVG--AARAAAHLTVIEKLRIVVPLKDT--RVKEQQEVVFNCE 13589
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQ 352
VN + W N + + + IL+ L L I++ H DDQ Y +N R +
Sbjct: 13590 VNTEGAK-AKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGE 13646
Score = 37.1 bits (82), Expect = 0.098
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQ 343
K + + +D G P V W +G+TL+ R+ + L IK K+D G Y+
Sbjct: 26334 KAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE 26393
Query: 344 CFASNA 349
SN+
Sbjct: 26394 LCVSNS 26399
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/98 (20%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
++P + + + I+ G+D+++ V P P W + P+++TT
Sbjct: 25237 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGE----PLKQTTRVNVEETAT 25292
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
+L I++ ++D G++ N+ G+ + + ++IV E
Sbjct: 25293 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE 25330
Score = 36.3 bits (80), Expect = 0.17
Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R+G +V L P P+ W + P++E+ + ++ ++ LSI+ ++E
Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDG----LPLKESEFVRFSKTENKITLSIKNAKKEH 28557
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPIS 275
G++ L+N V +V T+I P S
Sbjct: 28558 GGKYTVILDNAVCRIAVPITVITLGPPS 28585
Score = 35.9 bits (79), Expect = 0.23
Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 4/118 (3%)
Query: 173 GGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
G P E + R G V P PT WF E+ + T + T +
Sbjct: 3617 GPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-- 3674
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTKPEVLRSKPKS 289
G + +RED+G ++C N +G + L+V E + P +S P++
Sbjct: 3675 -GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEA 3731
Score = 35.9 bits (79), Expect = 0.23
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILED--GLRLHIKNTHKDD 338
+V+ + I + +V G P + W G+ L +R+++++D + L IK + D
Sbjct: 18843 DVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRAD 18902
Query: 339 QGIYQCFASNARDQAYG 355
G Y A N+ A G
Sbjct: 18903 HGKYIISAKNSSGHAQG 18919
Score = 35.9 bits (79), Expect = 0.23
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 8/86 (9%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQKVRRE 246
+R G +RL A P PT W P +L D L+++ R
Sbjct: 29296 VRAGASIRLFIAYQGRPTPTAVWS-------KPDSNLSLRADIHTTDSFSTLTVENCNRN 29348
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTE 272
DAG++ + N GS+S+ FT+ V +
Sbjct: 29349 DAGKYTLTVENNSGSKSITFTVKVLD 29374
Score = 35.5 bits (78), Expect = 0.30
Identities = 35/161 (21%), Positives = 60/161 (37%), Gaps = 7/161 (4%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G DV L C + P W + + + + +K + L I + D G
Sbjct: 7399 GSDVILQCEISGTPPFEVVWVKDRKQ----VRNSKKFKITSKHFDTSLHILNLEASDVGE 7454
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG-HPIELVYWLH 309
+ C N VGS++ ++ EP K + + L V G PI +V+
Sbjct: 7455 YHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKD 7514
Query: 310 NGRTLEPNE--RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G + +E RI +++ L + + + G Y C N
Sbjct: 7515 RGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKN 7555
Score = 35.5 bits (78), Expect = 0.30
Identities = 19/52 (36%), Positives = 23/52 (44%)
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V+G P V W N RTL IE + IKN + QG+Y A N
Sbjct: 17475 VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKN 17526
Score = 35.5 bits (78), Expect = 0.30
Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEI-LEDGL-RLHI 331
+SV K +L K +++ LD V G P+ V W +G L+P E I++ ++ L L +
Sbjct: 20224 LSVAMK-SLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLEL 20282
Query: 332 KNTHKDDQGIYQCFASNA 349
+ ++ D G Y A N+
Sbjct: 20283 FSVNRKDSGDYTITAENS 20300
Score = 35.1 bits (77), Expect = 0.39
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 9/91 (9%)
Query: 267 TLIVTEPISVRTKPEVLRSKPKS-------DIALDCKVNGHPIELVYWLHNGRTLEPNER 319
T V P+ + P L S K+ + L+C ++G+P V W +E +
Sbjct: 929 TARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSID 988
Query: 320 IEI-LEDGL-RLHIKNTHKDDQGIYQCFASN 348
+I + G+ RL I+ +D G + C A N
Sbjct: 989 FQITFQSGIARLMIREAFAEDSGRFTCSAVN 1019
Score = 35.1 bits (77), Expect = 0.39
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 6/69 (8%)
Query: 288 KSDIALDCKVNGH-PIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQC 344
K +I L C+V+ P++ W +G + P+ + I DGLR L IK D+G Y C
Sbjct: 12604 KDEITLKCEVSKDVPVK---WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVC 12660
Query: 345 FASNARDQA 353
+ +A
Sbjct: 12661 DCGTDKTKA 12669
Score = 34.3 bits (75), Expect = 0.69
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 4/87 (4%)
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEI---LEDG-LRLHIKN 333
TKP V + + C+V G+P VYW +G L R ++ + G +L I
Sbjct: 1086 TKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISM 1145
Query: 334 THKDDQGIYQCFASNARDQAYGMSEYL 360
T DD G Y N + + L
Sbjct: 1146 TFADDAGEYTIVVRNKHGETSASASLL 1172
Score = 34.3 bits (75), Expect = 0.69
Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 283 LRSKPKSDIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILED--GLRLHIKNTHKDD 338
LR K +C++ G P +V WLH+G+ LE R+ ++ + L + D
Sbjct: 1712 LRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRD 1771
Query: 339 QGIYQCFASN 348
GI C A+N
Sbjct: 1772 SGIITCRATN 1781
Score = 34.3 bits (75), Expect = 0.69
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR-LHIKNTHKDD 338
PE +R C+V G+P V W NG+ + ++R + DG+ L I + D
Sbjct: 1847 PEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYD 1906
Query: 339 QGIYQCFASN 348
G + A N
Sbjct: 1907 TGEVKVTAEN 1916
Score = 34.3 bits (75), Expect = 0.69
Identities = 37/172 (21%), Positives = 65/172 (37%), Gaps = 6/172 (3%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G + L C V WF + +Q+ ++ L+ + L+ L I D G
Sbjct: 4772 GTNALLQCEVSGTGPFEISWF-KDKKQIRSSKKYRLFSQKSLV---CLEIFSFNSADVGE 4827
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN 310
+ C + N VG T ++ EP + K + L + + L V G V W+
Sbjct: 4828 YECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKG 4887
Query: 311 GRTLEPNERIEI-LEDGLR-LHIKNTHKDDQGIYQCFASNARDQAYGMSEYL 360
+ + +I++ +G+ L I + G Y C A N + E +
Sbjct: 4888 QEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELI 4939
Score = 34.3 bits (75), Expect = 0.69
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
+L+I+ D G ++ T G + SV LI+ P E D C
Sbjct: 13716 MLTIKDCGFPDEGEYIV----TAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSC 13771
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
+++ V W NGR ++ ++ + +DG RL IK+ DD+ Y C + + +A
Sbjct: 13772 QLSREKAN-VKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRA 13830
Score = 34.3 bits (75), Expect = 0.69
Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 144 FLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAW 203
++ RVR + I + + +S +V + KP + +E + G+ + +P A
Sbjct: 15283 YVLRVR-AVNAIGVSEPSEISENVVAKDPD-CKPTIDLETHDIIVIEGEKLSIPVPFRAV 15340
Query: 204 PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
PVPT W + E + K + L + K R DAG + L N +GS +
Sbjct: 15341 PVPTVSWHKDGKE--VKASDRLTMKNDHI--SAHLEVPKSVRADAGIYTITLENKLGSAT 15396
Query: 264 VHFTLIV 270
+ V
Sbjct: 15397 ASINVKV 15403
Score = 34.3 bits (75), Expect = 0.69
Identities = 17/58 (29%), Positives = 24/58 (41%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L + G P V W R RI++ G +L I+N +D GIY N
Sbjct: 18163 LRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVEN 18220
Score = 34.3 bits (75), Expect = 0.69
Identities = 22/98 (22%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP V + + ++ + +++ P T W + ++ETT +
Sbjct: 26320 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNW----RKDGQTLKETTRVNVSSSKT 26375
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
LSI++ +ED G + ++N+ GS +V T+IV +
Sbjct: 26376 VTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLD 26413
Score = 34.3 bits (75), Expect = 0.69
Identities = 18/70 (25%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILE--DGLRLHIKNTHKDDQGIYQ 343
K + + V G P+ V W +G +E +EI + L +++ +D +G+Y
Sbjct: 28898 KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYT 28957
Query: 344 CFASNARDQA 353
A NA A
Sbjct: 28958 VEAKNASGSA 28967
Score = 33.9 bits (74), Expect = 0.91
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 290 DIA-LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFA 346
D+A L V G P + W NG L P+ + + DG L I T +D+G Y C A
Sbjct: 3518 DVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMA 3577
Query: 347 SN 348
SN
Sbjct: 3578 SN 3579
Score = 33.9 bits (74), Expect = 0.91
Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
G++VC N G + L V EP ++ + + L K +G W
Sbjct: 5481 GKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWF 5540
Query: 309 HNGR--TLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
+G+ TL +I + + L I +T K D G Y
Sbjct: 5541 KDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEY 5576
Score = 33.9 bits (74), Expect = 0.91
Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRI---RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
S VI+ EP+ ++P + + ++ + G + + P P W E
Sbjct: 29561 SSVIIKEPQ--IEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMR---- 29614
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
++ET D L+++ R D+GR+ L NT G ++ T++V
Sbjct: 29615 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 29664
Score = 32.7 bits (71), Expect = 2.1
Identities = 50/221 (22%), Positives = 89/221 (40%), Gaps = 17/221 (7%)
Query: 138 SDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPRVSVEQRS--RRIRVGQDV 194
S++ R + +V D G+ + V+ V EP +P V+ EQ + RR+ V D
Sbjct: 29426 SEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDV-VDT 29484
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEE--TTLWKRARLLDEGLLSIQKVRREDAGRFV 252
AV AW P + L + + + W A + +++++ + F
Sbjct: 29485 SKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFR 29544
Query: 253 CWLNNTVG-SE--SVHFTLIVTEPISVRTKP------EVLRSKPKSDIALDCKVNGHPIE 303
N G SE ++I+ EP T +++ K S +D ++G P
Sbjct: 29545 VKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAP 29604
Query: 304 LVYWLHNGRTLEPNERIEI--LEDGLRLHIKNTHKDDQGIY 342
V W L+ +R+ I +D L +K++ + D G Y
Sbjct: 29605 KVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRY 29645
Score = 32.3 bits (70), Expect = 2.8
Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
Query: 209 RWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL 268
+WF ++ E + P ++ L ++ L +Q + DAG + VG L
Sbjct: 2826 KWFHKNVE-IKPSDKHRLVSERKVHK---LMLQNISPSDAGEYTA----VVGQLECKAKL 2877
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR 328
V +T + + K+ + +C+V+ + + WL NG +E +E+ +I+ G +
Sbjct: 2878 FVETLHITKTMKNIEVPETKT-ASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-K 2934
Query: 329 LH---IKNTHKDDQGIYQCFASN 348
LH I NT +D Y N
Sbjct: 2935 LHQLIIMNTSTEDSAEYTFVCGN 2957
Score = 32.3 bits (70), Expect = 2.8
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 166 VIVTEPKGGVKPRVSVEQRSR-RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
V V EP+ + V + +I G+ +R+P V PVPT W E E ++
Sbjct: 16020 VTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL---DKDR 16076
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSE 262
+ E L I+ R+D GR+V N+ GS+
Sbjct: 16077 VVIDNVGTKSE--LIIKDALRKDHGRYVITATNSCGSK 16112
Score = 32.3 bits (70), Expect = 2.8
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 175 VKPRV--SVEQRSR-RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRAR 231
V PR+ SV +S ++ G +V L V P+PT W + L P E + +
Sbjct: 20218 VPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK-KDGTLLKPAEGIKMAMQRN 20276
Query: 232 LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
L L S V R+D+G + N+ GS+S L V +
Sbjct: 20277 LCTLELFS---VNRKDSGDYTITAENSSGSKSATIKLKVLD 20314
Score = 32.3 bits (70), Expect = 2.8
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 274 ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIE--ILEDGLRLHI 331
+ V+ K V+ K L+ V+G P + W +G+ LE ++E I + L
Sbjct: 22390 VDVKFKDTVIL-KAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVN 22448
Query: 332 KNTHKDDQGIYQCFASNARDQAYGMSEYLFDGNVL 366
K++ + D G Y A+N G ++++F+ VL
Sbjct: 22449 KDSTRRDSGAYTLTATNPG----GFAKHIFNVKVL 22479
Score = 32.3 bits (70), Expect = 2.8
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL--TPIEETTLWKRARLLDEGLLSIQKVRR 245
IR +RL + P P +W +H E L IE T+ + LL + V R
Sbjct: 22799 IRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYT--------LLIVGNVNR 22850
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTE 272
D+G+++ + N+ GS+S + V +
Sbjct: 22851 FDSGKYILTVENSSGSKSAFVNVRVLD 22877
Score = 31.9 bits (69), Expect = 3.7
Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 288 KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQC 344
K ++ L C+++ V W +G+ ++P++ I DG + L +K K D G Y C
Sbjct: 12959 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC 13016
Score = 31.9 bits (69), Expect = 3.7
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASN 348
L+ V+G P+ + WL + +E + R EI + L +K+ + D G Y ASN
Sbjct: 24572 LEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASN 24629
Score = 31.9 bits (69), Expect = 3.7
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Query: 177 PRVSVEQRSRR---IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
P + ++ R+ +R G R+ P P W E E ++ + K
Sbjct: 24949 PELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IEKGVNYT 25005
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
LSI R DAG+++ L N+ GS+S T+ V +
Sbjct: 25006 Q---LSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLD 25041
Score = 31.1 bits (67), Expect = 6.4
Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 10/91 (10%)
Query: 184 RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP--IEETTLWKRARLLDEGLLSIQ 241
R + I+VG +RL + P P W E + T I+ T + + L I+
Sbjct: 18153 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--------LEIR 18204
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
ED G + + N GS++V ++V +
Sbjct: 18205 NAAHEDGGIYSLTVENPAGSKTVSVKVLVLD 18235
Score = 31.1 bits (67), Expect = 6.4
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 281 EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDD 338
E L K + + + G P+ W +G ++ +E + D L IKN + D
Sbjct: 18445 EGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRD 18504
Query: 339 QGIYQCFASNA 349
G YQ SNA
Sbjct: 18505 TGEYQITVSNA 18515
Score = 30.7 bits (66), Expect = 8.5
Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+E L PI T A+ L+EG +VR E+A T +++V I +
Sbjct: 15557 NEHLVPILTYT----AKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVD--PIDAPKV 15610
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE 318
+RT EV R +IALD ++G P + W+ + + P E
Sbjct: 15611 ILRTSLEVKRG---DEIALDASISGSPYPTITWIKDENVIVPEE 15651
Score = 30.7 bits (66), Expect = 8.5
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V E K + P + I+ G+ +R+ V+ P PT +W E +T +
Sbjct: 19817 VYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVH 19875
Query: 228 KRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
K +L I+ V R+D+G + N+ G+++ ++V +
Sbjct: 19876 KAD---SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMD 19917
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 77.4 bits (182), Expect = 7e-14
Identities = 53/181 (29%), Positives = 79/181 (43%), Gaps = 9/181 (4%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDE 235
P+ V R + + G+ V PC P P W E + L P + R +
Sbjct: 35 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 94
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD- 294
G L+I ++R DAG ++C GS L VT+ ++ R P +L+ +A+D
Sbjct: 95 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDG 154
Query: 295 -----CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
CK G P+ ++ WL G T + R I E G L IKN D G Y C A++
Sbjct: 155 TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQG-TLQIKNLRISDTGTYTCVATS 213
Query: 349 A 349
+
Sbjct: 214 S 214
Score = 37.5 bits (83), Expect = 0.074
Identities = 52/235 (22%), Positives = 84/235 (35%), Gaps = 21/235 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSP--WEVHVPDEYVIAGNAVVLRCVVPPHCADRIS 102
Y C + VG + S + V A +P + V D+ V G V C + +
Sbjct: 8 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF 67
Query: 103 STEWLNDDDINVL-----HYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRT 157
W + N+L S+ G L I+ + SD ++C+ I
Sbjct: 68 ---WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDA-GYYICQALTVAGSILA 123
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
V+ V+ P P + ++ + V L C P+P W E
Sbjct: 124 KAQLEVTDVLTDRPP----PIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFT- 178
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P + RA + ++G L I+ +R D G + C ++ G S L VTE
Sbjct: 179 -FPGRDP----RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 228
Score = 36.7 bits (81), Expect = 0.13
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 17/114 (14%)
Query: 247 DAGRFVCWLNNTVGSESVHFTLIV-TEPIS-----VRTKPEVLRSKPKSDIALDCKVNGH 300
D G ++C N VG TL V P++ VR + +++ + C+ G+
Sbjct: 4 DEGTYMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQ--GRTVTFPCETKGN 61
Query: 301 PIELVYWLHNG--------RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
P V+W G + +PN R + G L I N + D G Y C A
Sbjct: 62 PQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG-DLTITNIQRSDAGYYICQA 114
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/263 (27%), Positives = 107/263 (40%), Gaps = 21/263 (7%)
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
D + + W DD S+Y DD +L I V+ D + + C V + + G A
Sbjct: 249 DPVPTVRWRKDDG----ELPKSRYEIRDDHTLKIRKVTAGDMGS-YTC-VAENMVGKAEA 302
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
TL V P VKPR V + +G+ V C P P W E + L
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQV------VALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 219 T-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR 277
+ R + G L+I V+R D G ++C N GS L VT+ I+ R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 278 TKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLH 330
P + + +A+D C G P+ + W +G + + RI+ LE+G+ L
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV-LQ 475
Query: 331 IKNTHKDDQGIYQCFASNARDQA 353
I+ D G Y C AS +A
Sbjct: 476 IRYAKLGDTGRYTCIASTPSGEA 498
Score = 57.2 bits (132), Expect = 9e-08
Identities = 91/347 (26%), Positives = 129/347 (37%), Gaps = 46/347 (13%)
Query: 18 RQILKNGSLEILPFT-AELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAA-LSSPWEVH 75
R +L +GSL L R D VY C R+ +G A+S N + A L + +
Sbjct: 80 RMLLPSGSLFFLRIVHGRKSRPD--EGVYVCVARNYLGE-AVSHNASLEVAILRDDFRQN 136
Query: 76 VPDEYVIAGNAVVLRCVVPP-HCADRISSTEWLNDDDINVLHYLGSKYHRLD--DGSLYI 132
D V+ G V+ C P H IS W D L K R+ G L I
Sbjct: 137 PSDVMVVVGEPAVMECQPPRGHPEPTIS---WKKDGSP-----LDDKDERITIRGGKLMI 188
Query: 133 SAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQ 192
+ SD +++C V + G R + V+ + V E VK + + V
Sbjct: 189 TYTRKSDA-GKYVC-VGTNMVGERESE---VAELTVLERPSFVK-----RPSNLAVTVDD 238
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
C PVPT RW + E P R + D+ L I+KV D G +
Sbjct: 239 SAEFKCEARGDPVPTVRWRKDDGE--LP------KSRYEIRDDHTLKIRKVTAGDMGSYT 290
Query: 253 CWLNNTVGSESVHFTLIV---TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
C N VG TL V +EP KP + C+ G+P ++W
Sbjct: 291 CVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRR 350
Query: 310 NGR-----TLEP---NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G + +P + R + + G L I N + D G Y C N
Sbjct: 351 EGSQNLLFSYQPPQSSSRFSVSQTG-DLTITNVQRSDVGYYICQTLN 396
Score = 48.4 bits (110), Expect = 4e-05
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 11/180 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W ++ E++ ++ R L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEW-YKGGERVETDKDDPRSHRMLLPSGS 87
Query: 237 LLSIQKVR----REDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKSD 290
L ++ V R D G +VC N +G H + + R P +
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVVGEP 147
Query: 291 IALDCK-VNGHPIELVYWLHNGRTL-EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++C+ GHP + W +G L + +ERI I G +L I T K D G Y C +N
Sbjct: 148 AVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGKLMITYTRKSDAGKYVCVGTN 205
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLE-----PNERIEILEDGLRLHIKNTH----KDDQGIYQ 343
L+CK G P + W G +E P +L G ++ H + D+G+Y
Sbjct: 48 LNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYV 107
Query: 344 CFASNARDQA 353
C A N +A
Sbjct: 108 CVARNYLGEA 117
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/263 (27%), Positives = 107/263 (40%), Gaps = 21/263 (7%)
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
D + + W DD S+Y DD +L I V+ D + + C V + + G A
Sbjct: 249 DPVPTVRWRKDDG----ELPKSRYEIRDDHTLKIRKVTAGDMGS-YTC-VAENMVGKAEA 302
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
TL V P VKPR V + +G+ V C P P W E + L
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQV------VALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 219 T-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR 277
+ R + G L+I V+R D G ++C N GS L VT+ I+ R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 278 TKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLH 330
P + + +A+D C G P+ + W +G + + RI+ LE+G+ L
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV-LQ 475
Query: 331 IKNTHKDDQGIYQCFASNARDQA 353
I+ D G Y C AS +A
Sbjct: 476 IRYAKLGDTGRYTCIASTPSGEA 498
Score = 55.6 bits (128), Expect = 3e-07
Identities = 49/164 (29%), Positives = 68/164 (41%), Gaps = 13/164 (7%)
Query: 188 IRVGQDVRLPCAV-HAWPVPTYRWFFEHHEQLTPIEETTLWKRARL-LDEGLLSIQKVRR 245
+ VG+ + C P PT W + +P+++ K R+ + G L I R+
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISW----KKDGSPLDD----KDERITIRGGKLMITYTRK 193
Query: 246 EDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
DAG++VC N VG ES L V E S +P L C+ G P+
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 253
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V W + L P R EI +D L I+ D G Y C A N
Sbjct: 254 VRWRKDDGEL-PKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAEN 295
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 11/180 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W ++ E++ ++ R L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEW-YKGGERVETDKDDPRSHRMLLPSGS 87
Query: 237 LLSIQKVR----REDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKSD 290
L ++ V R D G +VC N +G H + + R P +
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEP 147
Query: 291 IALDCK-VNGHPIELVYWLHNGRTL-EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++C+ GHP + W +G L + +ERI I G +L I T K D G Y C +N
Sbjct: 148 AVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGKLMITYTRKSDAGKYVCVGTN 205
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLE-----PNERIEILEDGLRLHIKNTH----KDDQGIYQ 343
L+CK G P + W G +E P +L G ++ H + D+G+Y
Sbjct: 48 LNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYV 107
Query: 344 CFASNARDQA 353
C A N +A
Sbjct: 108 CVARNYLGEA 117
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/263 (27%), Positives = 107/263 (40%), Gaps = 21/263 (7%)
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
D + + W DD S+Y DD +L I V+ D + + C V + + G A
Sbjct: 249 DPVPTVRWRKDDG----ELPKSRYEIRDDHTLKIRKVTAGDMGS-YTC-VAENMVGKAEA 302
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
TL V P VKPR V + +G+ V C P P W E + L
Sbjct: 303 SATLTVQVGSEPPHFVVKPRDQV------VALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 219 T-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR 277
+ R + G L+I V+R D G ++C N GS L VT+ I+ R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 278 TKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLH 330
P + + +A+D C G P+ + W +G + + RI+ LE+G+ L
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV-LQ 475
Query: 331 IKNTHKDDQGIYQCFASNARDQA 353
I+ D G Y C AS +A
Sbjct: 476 IRYAKLGDTGRYTCIASTPSGEA 498
Score = 55.6 bits (128), Expect = 3e-07
Identities = 49/164 (29%), Positives = 68/164 (41%), Gaps = 13/164 (7%)
Query: 188 IRVGQDVRLPCAV-HAWPVPTYRWFFEHHEQLTPIEETTLWKRARL-LDEGLLSIQKVRR 245
+ VG+ + C P PT W + +P+++ K R+ + G L I R+
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISW----KKDGSPLDD----KDERITIRGGKLMITYTRK 193
Query: 246 EDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
DAG++VC N VG ES L V E S +P L C+ G P+
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 253
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V W + L P R EI +D L I+ D G Y C A N
Sbjct: 254 VRWRKDDGEL-PKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAEN 295
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 11/180 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W ++ E++ ++ R L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEW-YKGGERVETDKDDPRSHRMLLPSGS 87
Query: 237 LLSIQKVR----REDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKSD 290
L ++ V R D G +VC N +G H + + R P +
Sbjct: 88 LFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEP 147
Query: 291 IALDCK-VNGHPIELVYWLHNGRTL-EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++C+ GHP + W +G L + +ERI I G +L I T K D G Y C +N
Sbjct: 148 AVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGKLMITYTRKSDAGKYVCVGTN 205
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLE-----PNERIEILEDGLRLHIKNTH----KDDQGIYQ 343
L+CK G P + W G +E P +L G ++ H + D+G+Y
Sbjct: 48 LNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYV 107
Query: 344 CFASNARDQA 353
C A N +A
Sbjct: 108 CVARNYLGEA 117
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 74.9 bits (176), Expect = 4e-13
Identities = 71/263 (26%), Positives = 108/263 (41%), Gaps = 24/263 (9%)
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
D + + W DD S+Y DD +L I V+ D + + C V + + G A
Sbjct: 288 DPVPTVRWRKDDG----ELPKSRYEIRDDHTLKIRKVTAGDMGS-YTC-VAENMVGKAEA 341
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
TL V EP P V+ R + + +G+ V C P P W E + L
Sbjct: 342 SATLT----VQEP-----PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 392
Query: 219 T-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVR 277
+ R + G L+I V+R D G ++C N GS L VT+ I+ R
Sbjct: 393 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 452
Query: 278 TKPEVLRSKPKSDIALD------CKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLH 330
P + + +A+D C G P+ + W +G + + RI+ LE+G+ L
Sbjct: 453 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGV-LQ 511
Query: 331 IKNTHKDDQGIYQCFASNARDQA 353
I+ D G Y C AS +A
Sbjct: 512 IRYAKLGDTGRYTCIASTPSGEA 534
Score = 60.9 bits (141), Expect = 7e-09
Identities = 90/344 (26%), Positives = 126/344 (36%), Gaps = 43/344 (12%)
Query: 18 RQILKNGSLEILPFT-AELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAA-LSSPWEVH 75
R +L +GSL L R D VY C R+ +G A+S N + A L + +
Sbjct: 119 RMLLPSGSLFFLRIVHGRKSRPD--EGVYVCVARNYLGE-AVSHNASLEVAILRDDFRQN 175
Query: 76 VPDEYVIAGNAVVLRCVVPP-HCADRISSTEWLNDDDINVLHYLGSKYHRLD--DGSLYI 132
D V G V+ C P H IS W D L K R+ G L I
Sbjct: 176 PSDVMVAVGEPAVMECQPPRGHPEPTIS---WKKDGSP-----LDDKDERITIRGGKLMI 227
Query: 133 SAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQ 192
+ SD +++C V + G R + V+ + V E VK + + V
Sbjct: 228 TYTRKSDA-GKYVC-VGTNMVGERESE---VAELTVLERPSFVK-----RPSNLAVTVDD 277
Query: 193 DVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
C PVPT RW + E R + D+ L I+KV D G +
Sbjct: 278 SAEFKCEARGDPVPTVRWRKDDGELPK--------SRYEIRDDHTLKIRKVTAGDMGSYT 329
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
C N VG TL V EP KP + C+ G+P ++W G
Sbjct: 330 CVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 389
Query: 313 -----TLEP---NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ +P + R + + G L I N + D G Y C N
Sbjct: 390 QNLLFSYQPPQSSSRFSVSQTG-DLTITNVQRSDVGYYICQTLN 432
Score = 48.8 bits (111), Expect = 3e-05
Identities = 45/180 (25%), Positives = 70/180 (38%), Gaps = 11/180 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + G+ L C P PT W ++ E++ ++ R L
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEW-YKGGERVETDKDDPRSHRMLLPSGS 126
Query: 237 LLSIQKVR----REDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKSD 290
L ++ V R D G +VC N +G H + + R P +
Sbjct: 127 LFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEP 186
Query: 291 IALDCK-VNGHPIELVYWLHNGRTL-EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++C+ GHP + W +G L + +ERI I G +L I T K D G Y C +N
Sbjct: 187 AVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGKLMITYTRKSDAGKYVCVGTN 244
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLE-----PNERIEILEDGLRLHIKNTH----KDDQGIYQ 343
L+CK G P + W G +E P +L G ++ H + D+G+Y
Sbjct: 87 LNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYV 146
Query: 344 CFASNARDQA 353
C A N +A
Sbjct: 147 CVARNYLGEA 156
>AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein.
Length = 285
Score = 74.5 bits (175), Expect = 5e-13
Identities = 51/171 (29%), Positives = 75/171 (43%), Gaps = 9/171 (5%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V PC P P W E + L P + R + G L+I ++R DAG
Sbjct: 6 GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAG 65
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD------CKVNGHPIE 303
++C GS L VT+ ++ R P +L+ +A+D CK G P+
Sbjct: 66 YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP 125
Query: 304 LVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
++ WL G T + R I E G L IKN D G Y C A+++ +A
Sbjct: 126 VISWLKEGFTFPGRDPRATIQEQG-TLQIKNLRISDTGTYTCVATSSSGEA 175
Score = 34.3 bits (75), Expect = 0.69
Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 11/145 (7%)
Query: 128 GSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRR 187
G L I+ + SD ++C+ I V+ V+ P P + ++
Sbjct: 52 GDLTITNIQRSDA-GYYICQALTVAGSILAKAQLEVTDVLTDRPP----PIILQGPANQT 106
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ V L C P+P W E P + RA + ++G L I+ +R D
Sbjct: 107 LAVDGTALLKCKATGDPLPVISWLKEGFT--FPGRDP----RATIQEQGTLQIKNLRISD 160
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTE 272
G + C ++ G S L VTE
Sbjct: 161 TGTYTCVATSSSGEASWSAVLDVTE 185
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 73.7 bits (173), Expect = 9e-13
Identities = 78/310 (25%), Positives = 133/310 (42%), Gaps = 30/310 (9%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAAL-SSPWEVHVP-DEYVIAGNAVVLRCVVPPHCADRI 101
VY+C R+S G + Y++L + P V P D V+ G + L C+ H I
Sbjct: 302 VYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHPHPLI 361
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
+ W D N L GS++ G LY+ ++ D H RF C + ++ A N
Sbjct: 362 T---WTRD---NGLELDGSRHVATSSG-LYLQNITQRD-HGRFTCHANNSHGTVQAAAN- 412
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
+IV P P+ +V + + + V C P P W + QL P+
Sbjct: 413 ----IIVQAP-----PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWT-KTGGQL-PV 461
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT-EPISVRTK- 279
E + +L G L I + + D G++ C +++G + V L V + ++V T+
Sbjct: 462 EG-----QHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFTQL 516
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
P+ + +I + C G P ++ W G + + + + ++G L I + DQ
Sbjct: 517 PQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEG-TLTIYDAGFPDQ 575
Query: 340 GIYQCFASNA 349
G Y+C A N+
Sbjct: 576 GRYECVARNS 585
Score = 63.7 bits (148), Expect = 1e-09
Identities = 44/179 (24%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR++ E + + G V C P P W +H +E+ T R + D+G
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHS--LDLEDDT---RLNVFDDG 288
Query: 237 LLSIQKVRREDAGRFVCWLNNTVG-----SESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
L I+ R D G + C N+ G S + ++ + +P S +P+ +
Sbjct: 289 TLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKP-SFVIQPQDTEVLIGTST 347
Query: 292 ALDCKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C GHP L+ W NG L+ + + L+++N + D G + C A+N+
Sbjct: 348 TLECMATGHPHPLITWTRDNGLELDGSRHVATSSG---LYLQNITQRDHGRFTCHANNS 403
Score = 58.8 bits (136), Expect = 3e-08
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 16/221 (7%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
DDG+L I SD+ + C R+ +T L + +P ++P+
Sbjct: 286 DDGTLMIRNTRESDQ-GVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQ------D 338
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+ +G L C P P W ++ +L R GL +Q + +
Sbjct: 339 TEVLIGTSTTLECMATGHPHPLITWTRDNGLELDG-------SRHVATSSGLY-LQNITQ 390
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
D GRF C NN+ G+ +IV P P+ + + C+ +G+P ++
Sbjct: 391 RDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVI 450
Query: 306 YWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
W G L + +L G L I + DQG Y+C A
Sbjct: 451 VWTKTGGQLPVEGQHTVLSSG-TLRIDRAAQHDQGQYECQA 490
Score = 58.0 bits (134), Expect = 5e-08
Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 3/84 (3%)
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHK 336
+P+ + + + C+ G+P + W+HN +L E + R+ + +DG L I+NT +
Sbjct: 239 EPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGT-LMIRNTRE 297
Query: 337 DDQGIYQCFASNARDQAYGMSEYL 360
DQG+YQC A N+ +A S L
Sbjct: 298 SDQGVYQCMARNSAGEAKTQSAML 321
Score = 32.7 bits (71), Expect = 2.1
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+ VG+++ + C P P W +++ I E+ + + DEG L+I D
Sbjct: 522 VEVGKNINISCHAQGEPQPIITW----NKEGVQITESG---KFHVDDEGTLTIYDAGFPD 574
Query: 248 AGRFVCWLNNTVGSESVHFTLIVT 271
GR+ C N+ G + L VT
Sbjct: 575 QGRYECVARNSFGLAVTNMFLTVT 598
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 73.7 bits (173), Expect = 9e-13
Identities = 80/278 (28%), Positives = 114/278 (41%), Gaps = 26/278 (9%)
Query: 71 PWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSL 130
P V P+ V G VL C V ++ W+ D VL + +L D SL
Sbjct: 481 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT---WVRD--WRVLPASTGRVAQLADLSL 535
Query: 131 YISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV 190
IS + +D R+ C V G+ A L +V E P+VS+ S+
Sbjct: 536 EISGIIPTDG-GRYQC-VASNANGVTRASVWL----LVREA-----PQVSIHTSSQHFSQ 584
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G +V++ C+ +P P W E ++E + R + +G L IQ V EDAG
Sbjct: 585 GVEVKVSCSASGYPTPHISWSRESQA----LQEDS---RIHVDAQGTLIIQGVAPEDAGN 637
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN 310
+ C N VG++ TL T+P SV V+ + L C+ +G P V W
Sbjct: 638 YSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG 697
Query: 311 GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G LE E G +L I + D G Y C A N
Sbjct: 698 G--LEMILAPEGSSSG-KLRIPAAQERDAGTYTCRAVN 732
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 2/111 (1%)
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
I + + + G + C + G+ ++VT+P + P L C+V G
Sbjct: 446 ILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG 505
Query: 300 HPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W+ + R L + R+ L D L L I D G YQC ASNA
Sbjct: 506 EAPYNLTWVRDWRVLPASTGRVAQLAD-LSLEISGIIPTDGGRYQCVASNA 555
Score = 33.1 bits (72), Expect = 1.6
Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 20/151 (13%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S+ H G+L I V+ D N + C+ +++ + V + T+P P V
Sbjct: 615 SRIHVDAQGTLIIQGVAPEDAGN-YSCQATNEVGTDQETVT-----LYYTDP-----PSV 663
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
S + VG++ L C P P W+ E + E ++ G L
Sbjct: 664 SAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSS---------SGKLR 714
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
I + DAG + C N +G S L V
Sbjct: 715 IPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 73.3 bits (172), Expect = 1e-12
Identities = 63/240 (26%), Positives = 109/240 (45%), Gaps = 25/240 (10%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S+ L +G+L I V DR ++LC + + G H+ VT PR+
Sbjct: 1698 SRVQVLPNGTLSIQRVEIQDR-GQYLCSASN-LFG--------TDHLHVTLSVVSYPPRI 1747
Query: 180 SVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EG 236
+E+R++ I V G V L C P PT W + T + E++ R ++ +G
Sbjct: 1748 -LERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQ---TVVSESSQGSRQAVVTVDG 1803
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSES--VHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
L + + D G + C +N G +S V +I P+ + + +V+ + L
Sbjct: 1804 TLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLP 1863
Query: 295 CKVNGHPIELVYW-LHNGRTLEP----NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
C G P VYW L +G ++P N ++ + +G L+I+N D+G Y+C A+++
Sbjct: 1864 CTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNG-TLYIRNLASSDRGTYECIATSS 1922
Score = 71.7 bits (168), Expect = 4e-12
Identities = 56/187 (29%), Positives = 87/187 (46%), Gaps = 15/187 (8%)
Query: 176 KPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
KPR V + S I D LPC P+PT W + + R ++L
Sbjct: 1647 KPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHW--TRVPSGLDLSKRKQNSRVQVLP 1704
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEP---ISVRTKPEVLRSKPKSD 290
G LSIQ+V +D G+++C +N G++ +H TL +V+ P + RTK + S S
Sbjct: 1705 NGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHS--GST 1762
Query: 291 IALDCKVNGHPIELVYWLHNGRTL-----EPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L C+ G P V W+ +T+ + + + + DG L + N D+G Y+C
Sbjct: 1763 VELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDG-TLVLHNLSIYDRGFYKCV 1821
Query: 346 ASNARDQ 352
ASN Q
Sbjct: 1822 ASNPGGQ 1828
Score = 69.3 bits (162), Expect = 2e-11
Identities = 64/243 (26%), Positives = 102/243 (41%), Gaps = 22/243 (9%)
Query: 116 HYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGV 175
H +GS H +GSL+I +V+ D +LC R+K+ + ++ HV + +
Sbjct: 1987 HRVGSWIHVYPNGSLFIGSVTEKDS-GVYLCVARNKMGD-----DLILMHVSLR-----L 2035
Query: 176 KP-RVSVEQRSRR-IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT----LWKR 229
KP ++ +Q R+ + G+D ++ C PVP W + + +R
Sbjct: 2036 KPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRR 2095
Query: 230 ARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES--VHFTLIVTEPISVRTKPEVLRSKP 287
L + G L KV + G + C+ NT+G + VH T+I P ++ R K
Sbjct: 2096 YTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKA 2155
Query: 288 KSDIALDCKVNGHPIELVYWL--HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
LDC+V G P ++WL N +R +G L I D G Y C
Sbjct: 2156 GDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG-SLTINKVKLLDSGEYVCV 2214
Query: 346 ASN 348
A N
Sbjct: 2215 ARN 2217
Score = 58.8 bits (136), Expect = 3e-08
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 33/265 (12%)
Query: 103 STEWLNDD--DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN 160
S W+ D ++ L + SK +G+LYI +++SDR + C + TG V
Sbjct: 1873 SVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDR-GTYEC-IATSSTGSERRVV 1930
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
L VT P+ + Q+ + G + L C+ P P W +
Sbjct: 1931 MLTMEERVTSPR-----IEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQ 1985
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESV--HFTLIVTEPISVRT 278
W + G L I V +D+G ++C N +G + + H +L + +P +
Sbjct: 1986 QHRVGSW--IHVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRL-KPAKIDH 2042
Query: 279 K----PEVLRSKPKSDIALDCKVNGHPIELVYW-------LHNGRTLEPN----ERIEIL 323
K +VL K D +DCK +G P+ + W ++N + + R +
Sbjct: 2043 KQYFRKQVLHGK---DFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLF 2099
Query: 324 EDGLRLHIKNTHKDDQGIYQCFASN 348
+G L+ ++G Y C+A N
Sbjct: 2100 NNG-TLYFNKVGVAEEGDYTCYAQN 2123
Score = 56.8 bits (131), Expect = 1e-07
Identities = 47/186 (25%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 177 PRVSVEQRSRRI--RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P V +EQR + I G+ ++LPC P P+ W ++ P++ T + L
Sbjct: 1841 PPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTN--SKLFLFS 1898
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK------ 288
G L I+ + D G + C ++ GSE L + E + T P + + K
Sbjct: 1899 NGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV---TSPRIEAASQKRTEVNF 1955
Query: 289 -SDIALDCKVNGHPIELVYW-LHNGRTLEPNER----IEILEDGLRLHIKNTHKDDQGIY 342
+ L+C G P + W L + ++ R I + +G L I + + D G+Y
Sbjct: 1956 GDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNG-SLFIGSVTEKDSGVY 2014
Query: 343 QCFASN 348
C A N
Sbjct: 2015 LCVARN 2020
Score = 53.2 bits (122), Expect = 1e-06
Identities = 74/313 (23%), Positives = 129/313 (41%), Gaps = 23/313 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C ++++G M ++ V A + + ++ + AG+ VL C V D
Sbjct: 2117 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEV---TGDPKPKI 2173
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
WL + +++ + +Y +GSL I+ V D ++C R+ +G T + L
Sbjct: 2174 FWLLPSN-DMISFSIDRYTFHANGSLTINKVKLLD-SGEYVCVARNP-SGDDTKMYKL-- 2228
Query: 165 HVIVTEPK--GGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
+V++P G+ +V ++ +R + C P P W + LT
Sbjct: 2229 -DVVSKPPLINGLYTNRTV-IKATAVRHSKK-HFDCRAEGTPSPEVMWIMPDNIFLT--- 2282
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--KP 280
R + G L I+ VR D+ F+C N G + L V E + T P
Sbjct: 2283 APYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNP 2342
Query: 281 --EVLRSKPKSDIALDCKVNGH-PIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTH 335
E + ++ AL+C V+G+ P E+++ L NG P ++ I T
Sbjct: 2343 FNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTT 2402
Query: 336 KDDQGIYQCFASN 348
++D G Y+C A N
Sbjct: 2403 REDAGKYRCAARN 2415
Score = 52.8 bits (121), Expect = 2e-06
Identities = 81/366 (22%), Positives = 137/366 (37%), Gaps = 37/366 (10%)
Query: 3 WLQSDNTPV-ASLSGLR-QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK 60
W+ DN + A G R + KNG+LEI + + C R+ G +
Sbjct: 2273 WIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLS------DSADFICVARNEGGESVLVV 2326
Query: 61 NIHVYAALSSPWEVHVPDEYVIA--GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ V L P + +E ++A G + L C V + I W+ + +
Sbjct: 2327 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEII---WILPNGTRFSNGP 2383
Query: 119 GSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSH--VIVTEPKGGVK 176
S + + +I + +T + ++ C R+K+ I V + VI+T G VK
Sbjct: 2384 QSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVK 2443
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
+S G+ + L C P P +W ++ + + L D G
Sbjct: 2444 G-IS----------GESLSLHCVSDGIPKPNIKWTMPSGYV---VDRPQINGKYILHDNG 2489
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHF-TLIVTEPISVRTKP-EVLRSKPKSDIALD 294
L I++ D G ++C N+VG + +IV P + +P + ++ + L
Sbjct: 2490 TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLH 2549
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH------IKNTHKDDQGIYQCFASN 348
C G P + W +L E +LH I+N D GIY+C A N
Sbjct: 2550 CVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKN 2609
Query: 349 ARDQAY 354
Y
Sbjct: 2610 PLGSDY 2615
Score = 50.4 bits (115), Expect = 1e-05
Identities = 57/240 (23%), Positives = 102/240 (42%), Gaps = 29/240 (12%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+Y ++G+LY + V ++ + + C ++ + V+ V +T PR+
Sbjct: 2095 RYTLFNNGTLYFNKVGVAEEGD-YTCYAQNTLGKDEMKVHLTV----IT-----AAPRIR 2144
Query: 181 VEQRS-RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLL 238
++ +RI+ G L C V P P W ++ ++ I+ T G L
Sbjct: 2145 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN------GSL 2198
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVR---TKPEVLRSKP--KSDIA 292
+I KV+ D+G +VC N G ++ + L +V++P + T V+++ S
Sbjct: 2199 TINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKH 2258
Query: 293 LDCKVNGHPIELVYWL--HNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
DC+ G P V W+ N P RI + ++G L I+N D + C A N
Sbjct: 2259 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG-TLEIRNVRLSDSADFICVARN 2317
Score = 38.3 bits (85), Expect = 0.042
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW--LHNGRTL---EPNERIEIL 323
I +P V K SD L C+ G+P+ ++W + +G L + N R+++L
Sbjct: 1644 IFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVL 1703
Query: 324 EDGLRLHIKNTHKDDQGIYQCFASN 348
+G L I+ D+G Y C ASN
Sbjct: 1704 PNG-TLSIQRVEIQDRGQYLCSASN 1727
Score = 37.9 bits (84), Expect = 0.056
Identities = 38/167 (22%), Positives = 66/167 (39%), Gaps = 10/167 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE--GLLSIQKVRR 245
+ VG V L C P P W + + + + R+L + G L +Q
Sbjct: 487 VLVGGTVGLNCPGQGDPTPHVDWLLADGSK---VRAPYVSEDGRILIDKSGKLELQMADS 543
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD--CKVNGHPIE 303
D G + C +N ++ + + + V EP+ + + LD C G P
Sbjct: 544 FDTGVYHCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDA 603
Query: 304 LVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W+ G + + + ++L +G L I DQG Y+C A+N
Sbjct: 604 SISWVIPGNNVLYQSSRDKKVLNNGT-LRILQVTPKDQGYYRCVAAN 649
>AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein
protein.
Length = 584
Score = 73.3 bits (172), Expect = 1e-12
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 27/316 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C + VG M + V A ++ V G+ V + C +++
Sbjct: 78 YTCFAENQVGKDEMRVRVKVVTAPATIRNKTCLAVQVPYGDVVTVACEAKGEPMPKVT-- 135
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
WL+ + V+ KY DG+L I SD N + C VR+ R T+
Sbjct: 136 -WLSPTN-KVIPTSSEKYQIYQDGTLLIQKAQRSDSGN-YTCLVRNSAGEDR---KTVWI 189
Query: 165 HVIVTEPK--GGVKPRVSVEQRSRRIRVGQDVRL-PCAVHAWPVPTYRWFFEHHEQLTPI 221
HV V PK G P +V R I G +L C P P W F L
Sbjct: 190 HVNVQPPKINGNPNPITTV----REIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPA- 244
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTK 279
R + G L I+ +R+ D+ + VC N G + L V EP+ +
Sbjct: 245 --PYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHD 302
Query: 280 P--EVLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLEPNERIEIL---EDGLRLHIKN 333
P E + + I+L+C G P + W L NG L+ ++++ DG+ LHI
Sbjct: 303 PISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGM-LHISG 361
Query: 334 THKDDQGIYQCFASNA 349
D G Y+C A NA
Sbjct: 362 LSSVDAGAYRCVARNA 377
Score = 55.6 bits (128), Expect = 3e-07
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 29/278 (10%)
Query: 82 IAGNAVVLRCVVPPHCADRISSTEWL--NDDDINVLHYLGSKYHRLDDGSLYISAVSTSD 139
+AG+ + L C S W+ N D+ L YH+ D G L+IS +S+ D
Sbjct: 311 MAGHTISLNCSA---AGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD-GMLHISGLSSVD 366
Query: 140 RHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR-RIRVGQDVRLPC 198
+ C R+ V+ V G+KP S + + I G+ ++LPC
Sbjct: 367 A-GAYRCVARNAAGHTERLVSLKV----------GLKPEASKQYHNLVSIINGETLKLPC 415
Query: 199 AVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNT 258
+ W + L E R LLD G L++++ D G +VC +
Sbjct: 416 TPPGAGQGRFSWTLPNGMHL---EGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETE 472
Query: 259 VGSESVHF-TLIVTEPISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLE 315
G +++ P + ++P V+ ++P + + L+C G P + W L + L+
Sbjct: 473 YGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLK 532
Query: 316 PNERIEI-----LEDGLRLHIKNTHKDDQGIYQCFASN 348
+ + L L I++ + D G Y+C A N
Sbjct: 533 AGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKN 570
Score = 52.0 bits (119), Expect = 3e-06
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 12/224 (5%)
Query: 40 VHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCAD 99
V A YRC R++ G+ ++ V + + H +I G + L C P
Sbjct: 365 VDAGAYRCVARNAAGHTERLVSLKVGLKPEASKQYHNLVS-IINGETLKLPCTPPGAGQG 423
Query: 100 RISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
R S T N + LG + LD+G+L + S DR ++CR+ T +V
Sbjct: 424 RFSWT-LPNGMHLEGPQTLG-RVSLLDNGTLTVREASVFDR-GTYVCRME---TEYGPSV 477
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
++ VI P+ +P + R G V+L C P W L
Sbjct: 478 TSIPVIVIAYPPRITSEPTPVIYTRP-----GNTVKLNCMAMGIPKADITWELPDKSHLK 532
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
+ L+ L +G L+IQ + DAG + C N +GS+S
Sbjct: 533 AGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDS 576
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/177 (23%), Positives = 71/177 (40%), Gaps = 16/177 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + C P+P W ++ + E + ++ +G L IQK +R
Sbjct: 113 QVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSE-----KYQIYQDGTLLIQKAQRS 167
Query: 247 DAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTKPEVLRSKPK-----SDIALDCKVNGH 300
D+G + C + N+ G + + V +P + P + + + S +DCK G
Sbjct: 168 DSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGI 227
Query: 301 PIELVYWLHNGRTLEP----NERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P V W + P RI + +G L I++ K D C A N +A
Sbjct: 228 PTPRVLWAFPEGVVLPAPYYGNRITVHGNG-SLDIRSLRKSDSVQLVCMARNEGGEA 283
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 73.3 bits (172), Expect = 1e-12
Identities = 63/240 (26%), Positives = 109/240 (45%), Gaps = 25/240 (10%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRV 179
S+ L +G+L I V DR ++LC + + G H+ VT PR+
Sbjct: 325 SRVQVLPNGTLSIQRVEIQDR-GQYLCSASN-LFG--------TDHLHVTLSVVSYPPRI 374
Query: 180 SVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EG 236
+E+R++ I V G V L C P PT W + T + E++ R ++ +G
Sbjct: 375 -LERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQ---TVVSESSQGSRQAVVTVDG 430
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSES--VHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
L + + D G + C +N G +S V +I P+ + + +V+ + L
Sbjct: 431 TLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLP 490
Query: 295 CKVNGHPIELVYW-LHNGRTLEP----NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
C G P VYW L +G ++P N ++ + +G L+I+N D+G Y+C A+++
Sbjct: 491 CTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNG-TLYIRNLASSDRGTYECIATSS 549
Score = 71.7 bits (168), Expect = 4e-12
Identities = 56/187 (29%), Positives = 87/187 (46%), Gaps = 15/187 (8%)
Query: 176 KPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
KPR V + S I D LPC P+PT W + + R ++L
Sbjct: 274 KPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHW--TRVPSGLDLSKRKQNSRVQVLP 331
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEP---ISVRTKPEVLRSKPKSD 290
G LSIQ+V +D G+++C +N G++ +H TL +V+ P + RTK + S S
Sbjct: 332 NGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHS--GST 389
Query: 291 IALDCKVNGHPIELVYWLHNGRTL-----EPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L C+ G P V W+ +T+ + + + + DG L + N D+G Y+C
Sbjct: 390 VELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDG-TLVLHNLSIYDRGFYKCV 448
Query: 346 ASNARDQ 352
ASN Q
Sbjct: 449 ASNPGGQ 455
Score = 48.8 bits (111), Expect = 3e-05
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 14/140 (10%)
Query: 177 PRVSVEQRSRRI--RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P V +EQR + I G+ ++LPC P P+ W ++ P++ T + L
Sbjct: 468 PPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTN--SKLFLFS 525
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK------ 288
G L I+ + D G + C ++ GSE L + E + T P + + K
Sbjct: 526 NGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV---TSPRIEAASQKRTEVNF 582
Query: 289 -SDIALDCKVNGHPIELVYW 307
+ L+C G P + W
Sbjct: 583 GDKLLLNCSATGEPKPQIMW 602
Score = 38.3 bits (85), Expect = 0.042
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW--LHNGRTL---EPNERIEIL 323
I +P V K SD L C+ G+P+ ++W + +G L + N R+++L
Sbjct: 271 IFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVL 330
Query: 324 EDGLRLHIKNTHKDDQGIYQCFASN 348
+G L I+ D+G Y C ASN
Sbjct: 331 PNG-TLSIQRVEIQDRGQYLCSASN 354
Score = 35.9 bits (79), Expect = 0.23
Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 103 STEWLNDD--DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN 160
S W+ D ++ L + SK +G+LYI +++SDR + C + TG V
Sbjct: 500 SVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDR-GTYEC-IATSSTGSERRVV 557
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRW 210
L VT P+ + Q+ + G + L C+ P P W
Sbjct: 558 MLTMEERVTSPR-----IEAASQKRTEVNFGDKLLLNCSATGEPKPQIMW 602
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 72.9 bits (171), Expect = 2e-12
Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 14/176 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG L C A P W + E++ P+E +R + + G L I + EDAG
Sbjct: 437 VGYSAFLHCEFFASPEAVVSW--QKVEEVKPLEG----RRYHIYENGTLQINRTTEEDAG 490
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN-----GHPIEL 304
+ CW+ N +G +V L + +R P+ R + L C+ H ++L
Sbjct: 491 SYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKL 550
Query: 305 VYWLHNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G E N E I+ DG L I N +DQGIY C A A D A +++
Sbjct: 551 -SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQ 605
Score = 62.9 bits (146), Expect = 2e-09
Identities = 79/313 (25%), Positives = 126/313 (40%), Gaps = 23/313 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIH--VYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRIS 102
YRC + +G IAMS+ I V + P E P E V G+ +VL C PP +
Sbjct: 107 YRCFASNKLG-IAMSEEIEFIVPSVPKFPKEKIDPLE-VEEGDPIVLPCN-PPKGLPPLH 163
Query: 103 STEWLNDDDINVLHY-LGSKYHRLDDGSLYISAVSTSDRHNRFLC-----RVRDKITGIR 156
W+N I + H + + G LY + V D N + C R+R + +
Sbjct: 164 -IYWMN---IELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMP 219
Query: 157 TAVNTLVSHVIVT-EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ S+ I +PK + P S + S I G+ + L C P P W
Sbjct: 220 MKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDW----- 274
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
++ + + A+ L I+ V +D G + C +N +G+ + F +IV EP
Sbjct: 275 NKIGG--DLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPR 332
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
KP+ S+ L C+ G P + W NG ++ + + + N
Sbjct: 333 WTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVFPREISFTNLQ 392
Query: 336 KDDQGIYQCFASN 348
+ +YQC ASN
Sbjct: 393 PNHTAVYQCEASN 405
Score = 37.9 bits (84), Expect = 0.056
Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 195 RLPCAVHAWPVPTYRW------FFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
++ C P PT+ W F+ ++ P + + R+ +EG +S
Sbjct: 54 QIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF---RIPNEGHIS------HFQ 104
Query: 249 GRFVCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGHPIEL 304
G++ C+ +N +G SE + F ++ + P + K + L + I L C G P
Sbjct: 105 GKYRCFASNKLGIAMSEEIEF-IVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLH 163
Query: 305 VYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+YW++ +E +ER+ + + G KD + Y CFA+ R
Sbjct: 164 IYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPR 210
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 72.9 bits (171), Expect = 2e-12
Identities = 86/336 (25%), Positives = 132/336 (39%), Gaps = 24/336 (7%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
++L NGSL I Y+C + G I +S+ H+ + S +EV
Sbjct: 86 EVLSNGSLYISEVEGRRGEQSDEG-FYQCLAMNKYGAI-LSQKAHLALSTISAFEVQPIS 143
Query: 79 EYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTS 138
V G C + H I+ W + + L + L G L I VS
Sbjct: 144 TEVHEGGVARFACKISSHPPAVIT---W--EFNRTTLPMTMDRITALPTGVLQIYDVSQR 198
Query: 139 DRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPC 198
D N + C + + R ++ ++ + E K P + ++ + Q V L C
Sbjct: 199 DSGN-YRC-IAATVAHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLEC 256
Query: 199 AVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNT 258
P P W H+ + R+L G L I VR + AG +VC T
Sbjct: 257 MATGNPKPIISWSRLDHKSIDVFN-------TRVLGNGNLMISDVRLQHAGVYVCRAT-T 308
Query: 259 VGSESVHF---TLIVTEPISVRTKPEVLRSKPKSDIA-LDCKVNGHPIELVYWLHNGRTL 314
G+ + TL V P S PE L ++P++ A C+ G P + WL NGR +
Sbjct: 309 PGTRNFTVAMATLTVLAPPSFVEWPESL-TRPRAGTARFVCQAEGIPSPKMSWLKNGRKI 367
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
N RI++ +L I +D IYQC A N++
Sbjct: 368 HSNGRIKMYNS--KLVINQIIPEDDAIYQCMAENSQ 401
Score = 49.6 bits (113), Expect = 2e-05
Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 274 ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHI-- 331
+S +P+ + K + LDC+ +G V WL NG + N+RIE+L +G L+I
Sbjct: 39 LSFVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNG-SLYISE 97
Query: 332 ---KNTHKDDQGIYQCFASN 348
+ + D+G YQC A N
Sbjct: 98 VEGRRGEQSDEGFYQCLAMN 117
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 72.9 bits (171), Expect = 2e-12
Identities = 49/169 (28%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRED 247
+R G V L +A P P W+ ++ +T + L D +L I+K D
Sbjct: 109 VREGTSVSLEXESNAVPPPVITWY-KNGRMITESTHVEI-----LADGQMLHIKKAEVSD 162
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVR-TKPEVLRSKPKSDIALDCKVNGHPIELVY 306
G++VC N G + +F L V P S+ + EV+ + + L C G P +
Sbjct: 163 TGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIA 222
Query: 307 WLHNGRTLEPNERIE--ILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
WL N + +E ++ +E IL G +L I + D G Y C ASN +A
Sbjct: 223 WLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA 271
Score = 72.5 bits (170), Expect = 2e-12
Identities = 78/303 (25%), Positives = 130/303 (42%), Gaps = 34/303 (11%)
Query: 55 YIAMSKNIHVYAALSSPWEVHVPDE-------YVIAGNA-VVLRCVVPPHCADRISSTEW 106
Y M+ N+ ++ S+ VHVP Y + N+ +L CV I+ W
Sbjct: 1184 YTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAIN---W 1240
Query: 107 LNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHV 166
D++ + + LG KY G L + V D + F V + G T +L HV
Sbjct: 1241 -KKDNVLLANLLG-KYTAEPYGELILENVVLED--SGFYTCVANNAAGEDTHTVSLTVHV 1296
Query: 167 IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTL 226
+ T + + VS+ + G+ +RL C P+P W F ++ + P ++
Sbjct: 1297 LPTFTE--LPGDVSLNK-------GEQLRLSCKATGIPLPKLTWTFNNN--IIPAHFDSV 1345
Query: 227 WKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRS 285
+ L+ I++V +ED+G +VC N+VG +++ F + P+ P
Sbjct: 1346 NGHSELV------IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIE 1399
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
+ L+C+V G P + W G +E + RI L +G L I T +D G Y C
Sbjct: 1400 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCV 1458
Query: 346 ASN 348
A+N
Sbjct: 1459 ATN 1461
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/332 (26%), Positives = 128/332 (38%), Gaps = 33/332 (9%)
Query: 19 QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPD 78
+IL +G++EIL HA Y C R++ G +HV+ P P
Sbjct: 983 RILSSGAIEILATQLN------HAGRYTCVARNAAGSAHRHVTLHVH---EPPVIQPQPS 1033
Query: 79 E-YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
E +VI N ++L C + I+ W + INV + G + L G L IS
Sbjct: 1034 ELHVILNNPILLPCEATGTPSPFIT---W-QKEGINV-NTSGRNHAVLPSGGLQISRAVR 1088
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
D ++C V G TA+ + +V V P +S + I V + + L
Sbjct: 1089 EDA-GTYMC-VAQNPAG--TALGKIKLNV-------QVPPVISPHLKEYVIAVDKPITLS 1137
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C P P W H+ I E+ R R+L G L I V+ DAG + C N
Sbjct: 1138 CEADGLPPPDITW----HKDGRAIVESI---RQRVLSSGSLQITFVQPGDAGHYTCMAAN 1190
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPN 317
GS S L V P +R+ S L C +G P + W + L
Sbjct: 1191 VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANL 1250
Query: 318 ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
E L ++N +D G Y C A+NA
Sbjct: 1251 LGKYTAEPYGELILENVVLEDSGFYTCVANNA 1282
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/180 (30%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHE-QLTPIEETTLWKRAR 231
V P ++ R I V + V L C A P P W Q TP R R
Sbjct: 656 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP--------RVR 707
Query: 232 LLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
+L G L I D + C +N G + F L V P +++ P+ L
Sbjct: 708 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 767
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C G P + W +G L N R ILE+G LHI++ H D G Y C A+NA
Sbjct: 768 TVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-LHIQSAHVTDTGRYLCMATNA 826
Score = 69.3 bits (162), Expect = 2e-11
Identities = 47/164 (28%), Positives = 71/164 (43%), Gaps = 12/164 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + L C V +P P W +EQ + TL ++ G L I + + D
Sbjct: 16 VNNFISLTCEVSGFPPPDLSWL--KNEQPIKLNTNTL-----IVPGGRTLQIIRAKVSDG 68
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE----VLRSKPKSDIALDCKVNGHPIEL 304
G + C N G F+L V P S++ V+ + + ++L+ + N P +
Sbjct: 69 GEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPV 128
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NGR + + +EIL DG LHIK D G Y C A N
Sbjct: 129 ITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 172
Score = 68.1 bits (159), Expect = 5e-11
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LL 238
S E + V + L C P P W + P+ +T + + L G +L
Sbjct: 570 SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGR----PLPQTD---QVQTLGGGEVL 622
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALDCK 296
I + ED GR+ C ++ G + + + V P I+ +P + + L+CK
Sbjct: 623 RISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECK 682
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ P ++ WL NG L+ R+ IL G L I N D Y C ASN
Sbjct: 683 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN 734
Score = 67.3 bits (157), Expect = 8e-11
Identities = 60/253 (23%), Positives = 93/253 (36%), Gaps = 17/253 (6%)
Query: 103 STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTL 162
S W + + + + Y L GSL I + S D + C V + + V+
Sbjct: 872 SINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTAT-YECTVTNGAGDDKRTVDLT 930
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V V P ++ E + + C P P+ W ++ +L P
Sbjct: 931 VQ----------VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT-KNGIRLLPRG 979
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV 282
+ R+L G + I + AGR+ C N GS H TL V EP ++ +P
Sbjct: 980 DGY-----RILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSE 1034
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIY 342
L + I L C+ G P + W G + + R + L I ++D G Y
Sbjct: 1035 LHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTY 1094
Query: 343 QCFASNARDQAYG 355
C A N A G
Sbjct: 1095 MCVAQNPAGTALG 1107
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 14/195 (7%)
Query: 175 VKPRVSVEQRSRRIR-VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V P + +R + + V L C P PT W ++H+++ E + R+L
Sbjct: 187 VPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWL-KNHKRI----ENSDSLEVRIL 241
Query: 234 DEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSD 290
G L I + + D+G + C +N G ++ L + P SV P + +
Sbjct: 242 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN 301
Query: 291 IALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C NG P L+ WL +G+ + ERI + +G L+I D G Y C A+N
Sbjct: 302 VELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATN 361
Query: 349 ---ARDQAYGMSEYL 360
D+ + ++ Y+
Sbjct: 362 PAGEEDRIFNLNVYV 376
Score = 64.9 bits (151), Expect = 4e-10
Identities = 42/159 (26%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
+G + L C V P PT +W + + IE + R R L G L+I EDAG
Sbjct: 1401 LGGNAILNCEVKGDPTPTIQW----NRKGVDIE---ISHRIRQLGNGSLAIYGTVNEDAG 1453
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLH 309
+ C N G +L + P + +P I L+C+ G P + W
Sbjct: 1454 DYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSR 1513
Query: 310 NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G ++ ++R+ +L + L+I + K+D ++C A N
Sbjct: 1514 QGHSISWDDRVNVLSNN-SLYIADAQKEDTSEFECVARN 1551
Score = 64.5 bits (150), Expect = 6e-10
Identities = 35/114 (30%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP--ISVRTKPEVLRSKPKSDIALD 294
+L + K ED+G++ C +N G S HF L V EP I+ + E + + + L
Sbjct: 528 VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 587
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C +G P + W+ +GR L ++++ L G L I +D G Y C AS+
Sbjct: 588 CIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASS 641
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRRE 246
+ +G++V L C + P P +W + PI +R R+ G L+I
Sbjct: 296 VLLGENVELVCNANGIPTPLIQWLKDGK----PIASGET-ERIRVSANGSTLNIYGALTS 350
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVR---TKPEVLRSKPKSDIALDCKVNGHPIE 303
D G++ C N G E F L V ++R + E L + + I ++C+ G P
Sbjct: 351 DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP 410
Query: 304 LVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ WL NG L + I +L G + I D +Y C ASN
Sbjct: 411 QINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 455
Score = 54.0 bits (124), Expect = 8e-07
Identities = 50/225 (22%), Positives = 81/225 (36%), Gaps = 19/225 (8%)
Query: 125 LDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
L GSL I+ V D + C + + G + L HV PR+ +
Sbjct: 1166 LSSGSLQITFVQPGDA-GHYTCMAAN-VAGSSSTSTKLTVHV---------PPRIRSTEG 1214
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ LPC P P W ++ + L + G L ++ V
Sbjct: 1215 HYTVNENSQAILPCVADGIPTPAINWKKDN------VLLANLLGKYTAEPYGELILENVV 1268
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
ED+G + C NN G ++ +L V + P + + L CK G P+
Sbjct: 1269 LEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 1328
Query: 305 VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ W N + + + + L I+ K+D G Y C A N+
Sbjct: 1329 LTWTFNNNIIPAH--FDSVNGHSELVIERVSKEDSGTYVCTAENS 1371
Score = 52.8 bits (121), Expect = 2e-06
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK 288
R +L+ G L IQ D GR++C N G++ L V P S+ P +
Sbjct: 797 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 856
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTL--EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C+ G P + W NG L + N+ L L I + DD Y+C
Sbjct: 857 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 916
Query: 347 SN 348
+N
Sbjct: 917 TN 918
Score = 52.4 bits (120), Expect = 2e-06
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 10/162 (6%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDA 248
V + + C P P W + P+ L RLL G ++ I + + D
Sbjct: 394 VDTSINIECRATGTPPPQINWL----KNGLPLP---LSSHIRLLAAGQVIRIVRAQVSDV 446
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTK--PEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G ++ H+ L V P ++ E + S ++ C +G P +
Sbjct: 447 AVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 506
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
WL +G+ L + + + G+ L + +D G Y C ASN
Sbjct: 507 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 548
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/231 (24%), Positives = 92/231 (39%), Gaps = 35/231 (15%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYV--IAGNAVVLRCVVPPHCADRIS 102
Y C +SVG++ VY ++ P ++ + GNA+ L C V D
Sbjct: 1364 YVCTAENSVGFVKAIG--FVYVKEPPVFKGDYPSHWIEPLGGNAI-LNCEVK---GDPTP 1417
Query: 103 STEWLNDD-DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN- 160
+ +W DI + H + +L +GSL I D + + C ++ + +++
Sbjct: 1418 TIQWNRKGVDIEISH----RIRQLGNGSLAIYGTVNEDAGD-YTCVATNEAGVVERSMSL 1472
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
TL S I+T ++P +V I G + L C P PT W + H
Sbjct: 1473 TLQSPPIIT-----LEPVETV------INAGGKIILNCQATGEPQPTITWSRQGH----- 1516
Query: 221 IEETTLWK-RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ W R +L L I ++ED F C N +GS V +IV
Sbjct: 1517 ---SISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 1564
Score = 39.1 bits (87), Expect = 0.024
Identities = 24/76 (31%), Positives = 34/76 (44%)
Query: 273 PISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIK 332
P + K E L + I+L C+V+G P + WL N + ++ N I+ G L I
Sbjct: 2 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 61
Query: 333 NTHKDDQGIYQCFASN 348
D G Y C A N
Sbjct: 62 RAKVSDGGEYTCIAIN 77
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 72.9 bits (171), Expect = 2e-12
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 27/316 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C + VG M + V A ++ V G+ V + C +++
Sbjct: 2322 YTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVT-- 2379
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
WL+ + V+ KY DG+L I SD N + C VR+ R T+
Sbjct: 2380 -WLSPTN-KVIPTSSEKYQIYQDGTLLIQKAQRSDSGN-YTCLVRNSAGEDR---KTVWI 2433
Query: 165 HVIVTEPK--GGVKPRVSVEQRSRRIRVGQDVRL-PCAVHAWPVPTYRWFFEHHEQLTPI 221
HV V PK G P +V R I G +L C P P W F L
Sbjct: 2434 HVNVQPPKINGNPNPITTV----REIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPA- 2488
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTK 279
R + G L I+ +R+ D+ + VC N G + L V EP+ +
Sbjct: 2489 --PYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHD 2546
Query: 280 P--EVLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLEPNERIEIL---EDGLRLHIKN 333
P E + + I+L+C G P + W L NG L+ ++++ DG+ LHI
Sbjct: 2547 PISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGM-LHISG 2605
Query: 334 THKDDQGIYQCFASNA 349
D G Y+C A NA
Sbjct: 2606 LSSVDAGAYRCVARNA 2621
Score = 64.5 bits (150), Expect = 6e-10
Identities = 50/184 (27%), Positives = 82/184 (44%), Gaps = 11/184 (5%)
Query: 174 GVKPRVSVEQ-RSRRIRVGQDVRLPCAVHAWPVPTYRWF-FEHHEQLTPIEETTLWKRAR 231
G KP++ + ++ + D PC P P W +TP T +R
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTP---NTRIQRFE 1906
Query: 232 LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT--EPISVRTKPEVLRSKPKS 289
+L G L I+KV+ +D G+++C +N G + + L VT +P + + + +
Sbjct: 1907 VLKNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGD 1966
Query: 290 DIALDCKVNGHPIELVYWLHNGR----TLEPNERIEILEDGLRLHIKNTHKDDQGIYQCF 345
IA++C G P + W+ R T+ P E L + L IK D+G+Y+C
Sbjct: 1967 TIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCV 2026
Query: 346 ASNA 349
ASNA
Sbjct: 2027 ASNA 2030
Score = 62.9 bits (146), Expect = 2e-09
Identities = 58/238 (24%), Positives = 106/238 (44%), Gaps = 25/238 (10%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
++ L +G+L I V DR +++C + + G+ V L+S V V +P+ ++
Sbjct: 1904 RFEVLKNGTLVIRKVQVQDR-GQYMCTASN-LHGLDRMV-VLLS-VTVQQPQ-----ILA 1954
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH---EQLTPIEETTLWKRARLLDEGL 237
+ + +G + + C P P W F + ++P+E R L +
Sbjct: 1955 SHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVES-----RITLHENRT 2009
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT--EPISVRTKPEVLRSKPKSDIALDC 295
LSI++ D G + C +N G++S+ L V P+ + K E + P I + C
Sbjct: 2010 LSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHC 2069
Query: 296 KVNGHPIELVYW-LHNGRTLEPNE----RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P+ V W L +G + P++ + + +G L+I+N D G Y+C A+N
Sbjct: 2070 TAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNG-TLYIRNLAPKDSGRYECVAAN 2126
Score = 60.9 bits (141), Expect = 7e-09
Identities = 68/320 (21%), Positives = 124/320 (38%), Gaps = 28/320 (8%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VY+C ++ G +++ +HV A + + + + G ++ + C A + S
Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAK---AAPLPS 2078
Query: 104 TEWLNDD--DINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNT 161
W+ D I +L +G+LYI ++ D R+ C + + R V
Sbjct: 2079 VRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDS-GRYECVAANLVGSARRTVQL 2137
Query: 162 LVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPI 221
V G PR + +R G ++L C+ P P W + +
Sbjct: 2138 NVQRAAANARITGTSPRRT------DVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDAL 2191
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVRTKP 280
+ R ++ G L ++ V +DAG ++C N VG + V + +V +P + K
Sbjct: 2192 --FSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKE 2249
Query: 281 E-VLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLEP----------NERIEILEDGLR 328
E + D+ +DC G P + W L +G + +R + +G
Sbjct: 2250 ENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNG-T 2308
Query: 329 LHIKNTHKDDQGIYQCFASN 348
L+ ++G Y CFA N
Sbjct: 2309 LYFNEVGMREEGDYTCFAEN 2328
Score = 54.4 bits (125), Expect = 6e-07
Identities = 64/278 (23%), Positives = 112/278 (40%), Gaps = 29/278 (10%)
Query: 82 IAGNAVVLRCVVPPHCADRISSTEWL--NDDDINVLHYLGSKYHRLDDGSLYISAVSTSD 139
+AG+ + L C S W+ N D+ L YH+ D G L+IS +S+ D
Sbjct: 2555 MAGHTISLNCSA---AGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD-GMLHISGLSSVD 2610
Query: 140 RHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSR-RIRVGQDVRLPC 198
+ C R+ V+ V G+KP + + + I G+ ++LPC
Sbjct: 2611 A-GAYRCVARNAAGHTERLVSLKV----------GLKPEANKQYHNLVSIINGETLKLPC 2659
Query: 199 AVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNT 258
+ W + L E R LLD G L++++ D G +VC +
Sbjct: 2660 TPPGAGQGRFSWTLPNGMHL---EGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETE 2716
Query: 259 VGSESVHF-TLIVTEPISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYW-LHNGRTLE 315
G +++ P + ++P V+ ++P + + L+C G P + W L + L+
Sbjct: 2717 YGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLK 2776
Query: 316 PNERIEI-----LEDGLRLHIKNTHKDDQGIYQCFASN 348
+ + L L I++ + D G Y+C A N
Sbjct: 2777 AGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKN 2814
Score = 51.6 bits (118), Expect = 4e-06
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 12/224 (5%)
Query: 40 VHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCAD 99
V A YRC R++ G+ ++ V + + H +I G + L C P
Sbjct: 2609 VDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVS-IINGETLKLPCTPPGAGQG 2667
Query: 100 RISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV 159
R S T N + LG + LD+G+L + S DR ++CR+ T +V
Sbjct: 2668 RFSWT-LPNGMHLEGPQTLG-RVSLLDNGTLTVREASVFDR-GTYVCRME---TEYGPSV 2721
Query: 160 NTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
++ VI P+ +P + R G V+L C P W L
Sbjct: 2722 TSIPVIVIAYPPRITSEPTPVIYTRP-----GNTVKLNCMAMGIPKADITWELPDKSHLK 2776
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
+ L+ L +G L+IQ + DAG + C N +GS+S
Sbjct: 2777 AGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDS 2820
Score = 48.8 bits (111), Expect = 3e-05
Identities = 41/177 (23%), Positives = 71/177 (40%), Gaps = 16/177 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + C P+P W ++ + E + ++ +G L IQK +R
Sbjct: 2357 QVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSE-----KYQIYQDGTLLIQKAQRS 2411
Query: 247 DAGRFVCWLNNTVGSESVHFTLIV-TEPISVRTKPEVLRSKPK-----SDIALDCKVNGH 300
D+G + C + N+ G + + V +P + P + + + S +DCK G
Sbjct: 2412 DSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGI 2471
Query: 301 PIELVYWLHNGRTLEP----NERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
P V W + P RI + +G L I++ K D C A N +A
Sbjct: 2472 PTPRVLWAFPEGVVLPAPYYGNRITVHGNG-SLDIRSLRKSDSVQLVCMARNEGGEA 2527
Score = 45.2 bits (102), Expect = 4e-04
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 18/154 (11%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEP--KGGVKP 177
SK+ L G L I ++ SD + C I +R ++ +V V+V P + K
Sbjct: 530 SKFSILSSGWLRIKSMEPSDS-GLYQC-----IAQVRDEMDRMVYRVLVQSPSTQPAEKD 583
Query: 178 RVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL 237
V++ + G+ V LPC A P W + + + T+ +L G
Sbjct: 584 TVTIGKNP-----GESVTLPCNALAIPEAHLSWILPNRRIINDLANTS---HVYMLPNGT 635
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT 271
LSI KV+ D+G + C N G++ HFT+ +T
Sbjct: 636 LSIPKVQVSDSGYYRCVAVNQQGAD--HFTVGIT 667
Score = 42.3 bits (95), Expect = 0.003
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW--LHNGRTLEPN 317
G + F + +P + P+ + ++D C+ G P V W + G + PN
Sbjct: 1840 GPPASKFWSLGEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPN 1899
Query: 318 ERI---EILEDGLRLHIKNTHKDDQGIYQCFASN 348
RI E+L++G L I+ D+G Y C ASN
Sbjct: 1900 TRIQRFEVLKNG-TLVIRKVQVQDRGQYMCTASN 1932
Score = 33.9 bits (74), Expect = 0.91
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 293 LDCKVNGHPIELVYW-LHNGRTL-----EPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
L C V ++W L +G L +P+ + IL G L IK+ D G+YQC A
Sbjct: 499 LSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGW-LRIKSMEPSDSGLYQCIA 557
Query: 347 SNARDQ 352
RD+
Sbjct: 558 -QVRDE 562
>AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion
molecule protein.
Length = 1224
Score = 72.9 bits (171), Expect = 2e-12
Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 14/176 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG L C A P W + E++ P+E +R + + G L I + EDAG
Sbjct: 453 VGYSAFLHCEFFASPEAVVSW--QKVEEVKPLEG----RRYHIYENGTLQINRTTEEDAG 506
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN-----GHPIEL 304
+ CW+ N +G +V L + +R P+ R + L C+ H ++L
Sbjct: 507 SYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKL 566
Query: 305 VYWLHNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G E N E I+ DG L I N +DQGIY C A A D A +++
Sbjct: 567 -SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQ 621
Score = 53.6 bits (123), Expect = 1e-06
Identities = 80/329 (24%), Positives = 128/329 (38%), Gaps = 39/329 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIH--VYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRIS 102
YRC + +G IAMS+ I V + P E P E V G+ +VL C PP +
Sbjct: 107 YRCFASNKLG-IAMSEEIEFIVPSVPKFPKEKIDPLE-VEEGDPIVLPCN-PPKGLPPLH 163
Query: 103 STEWLNDDDINVLHY-LGSKYHRLDDGSLYISAVSTSDRHNRFLC-----RVRD------ 150
W+N I + H + + G LY + V D N + C R+R
Sbjct: 164 -IYWMN---IELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMP 219
Query: 151 -KIT----------GIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCA 199
K+T T + + + + +PK + P S + S I G+ + L C
Sbjct: 220 MKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECF 279
Query: 200 VHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTV 259
P P W ++ + + A+ L I+ V +D G + C +N +
Sbjct: 280 AEGLPTPQVDW-----NKIGG--DLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFL 332
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNER 319
G+ + F +IV EP KP+ S+ L C+ G P + W NG ++ +
Sbjct: 333 GTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPF 392
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ + N + +YQC ASN
Sbjct: 393 AGDVVFPREISFTNLQPNHTAVYQCEASN 421
Score = 37.9 bits (84), Expect = 0.056
Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 195 RLPCAVHAWPVPTYRW------FFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
++ C P PT+ W F+ ++ P + + R+ +EG +S
Sbjct: 54 QIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF---RIPNEGHIS------HFQ 104
Query: 249 GRFVCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGHPIEL 304
G++ C+ +N +G SE + F ++ + P + K + L + I L C G P
Sbjct: 105 GKYRCFASNKLGIAMSEEIEF-IVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLH 163
Query: 305 VYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+YW++ +E +ER+ + + G KD + Y CFA+ R
Sbjct: 164 IYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPR 210
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 72.9 bits (171), Expect = 2e-12
Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 14/176 (7%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG L C A P W + E++ P+E +R + + G L I + EDAG
Sbjct: 439 VGYSAFLHCEFFASPEAVVSW--QKVEEVKPLEG----RRYHIYENGTLQINRTTEEDAG 492
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVN-----GHPIEL 304
+ CW+ N +G +V L + +R P+ R + L C+ H ++L
Sbjct: 493 SYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKL 552
Query: 305 VYWLHNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G E N E I+ DG L I N +DQGIY C A A D A +++
Sbjct: 553 -SWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQ 607
Score = 62.9 bits (146), Expect = 2e-09
Identities = 79/313 (25%), Positives = 126/313 (40%), Gaps = 23/313 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIH--VYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRIS 102
YRC + +G IAMS+ I V + P E P E V G+ +VL C PP +
Sbjct: 109 YRCFASNKLG-IAMSEEIEFIVPSVPKFPKEKIDPLE-VEEGDPIVLPCN-PPKGLPPLH 165
Query: 103 STEWLNDDDINVLHY-LGSKYHRLDDGSLYISAVSTSDRHNRFLC-----RVRDKITGIR 156
W+N I + H + + G LY + V D N + C R+R + +
Sbjct: 166 -IYWMN---IELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMP 221
Query: 157 TAVNTLVSHVIVT-EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ S+ I +PK + P S + S I G+ + L C P P W
Sbjct: 222 MKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDW----- 276
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
++ + + A+ L I+ V +D G + C +N +G+ + F +IV EP
Sbjct: 277 NKIGG--DLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPR 334
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
KP+ S+ L C+ G P + W NG ++ + + + N
Sbjct: 335 WTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVFPREISFTNLQ 394
Query: 336 KDDQGIYQCFASN 348
+ +YQC ASN
Sbjct: 395 PNHTAVYQCEASN 407
Score = 37.9 bits (84), Expect = 0.056
Identities = 39/167 (23%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 195 RLPCAVHAWPVPTYRW------FFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
++ C P PT+ W F+ ++ P + + R+ +EG +S
Sbjct: 56 QIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF---RIPNEGHIS------HFQ 106
Query: 249 GRFVCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGHPIEL 304
G++ C+ +N +G SE + F ++ + P + K + L + I L C G P
Sbjct: 107 GKYRCFASNKLGIAMSEEIEF-IVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLH 165
Query: 305 VYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+YW++ +E +ER+ + + G KD + Y CFA+ R
Sbjct: 166 IYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPR 212
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 71.7 bits (168), Expect = 4e-12
Identities = 89/355 (25%), Positives = 143/355 (40%), Gaps = 36/355 (10%)
Query: 22 KNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHV----- 76
KN +L LPF + + T+ ++ V + N+ V LS+ VHV
Sbjct: 291 KNSNL--LPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 348
Query: 77 ----PDEY--VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLD-DGS 129
P E+ G V + CVV D + W D + LG +D S
Sbjct: 349 PFIQPFEFPRFSIGQRVFIPCVVVS--GDLPITITWQKDGR-PIPGSLGVTIDNIDFTSS 405
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIR 189
L IS +S N + C R++ + S +IV P P+ V+ R +
Sbjct: 406 LRISNLSLMHNGN-YTCIARNEAAAVEHQ-----SQLIVRVP-----PKFVVQPRDQDGI 454
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
G+ V L C+ +PVPT W F + + L R ++L G L I+ V ED+G
Sbjct: 455 YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSG 514
Query: 250 RFVCWLNNTVGSE-SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
++C ++N VG++ S L V P + + P + + C +G +V W
Sbjct: 515 YYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWE 574
Query: 309 HNGRTLEPN------ERIEILEDGL-RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
R + P E+ E+ + L I T ++D G + C A N+ + G+
Sbjct: 575 KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGI 629
Score = 71.3 bits (167), Expect = 5e-12
Identities = 45/143 (31%), Positives = 69/143 (48%), Gaps = 9/143 (6%)
Query: 204 PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
P P YRW ++ P+E L R + GLL I+ +R D+G +VC ++N G+
Sbjct: 4 PEPDYRWLKDN----MPLE---LSGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAK 55
Query: 264 VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEIL 323
V L V +P+ P ++S S ++L C V G + + W NG L P + + I
Sbjct: 56 VIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRIT 115
Query: 324 E-DGLRLHIKNTHKDDQGIYQCF 345
+ L + + K D G YQCF
Sbjct: 116 GINHENLIMDHMVKSDGGAYQCF 138
Score = 52.0 bits (119), Expect = 3e-06
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 11/174 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P++ + + + V L C V P+PT W + PI + + ++++ E
Sbjct: 159 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDD----PILKGGSHRISQMITSE 214
Query: 236 G----LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
G L+I + D G + C NN+ G + V P S+R + + D
Sbjct: 215 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGR-DT 273
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD-DQGIYQC 344
+ C+V G+P + W N L N R E+ L + + K+ D+G Y C
Sbjct: 274 YIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 327
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/326 (23%), Positives = 122/326 (37%), Gaps = 33/326 (10%)
Query: 44 VYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISS 103
VYRC +S G + I+V S ++ IAG + C V + S
Sbjct: 233 VYRCTANNSAGVVLYQARINVRGPASIRPMKNIT---AIAGRDTYIHCRVIGY---PYYS 286
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + N+L + + ++G+L +S V + C V ++ ++T
Sbjct: 287 IKWYKNS--NLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL-----VQPQLSTSQ 339
Query: 164 S-HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVP-TYRWFFEHHEQLTPI 221
S HV V P ++P R +GQ V +PC V + +P T W + PI
Sbjct: 340 SVHVTVKVPPF-IQPF-----EFPRFSIGQRVFIPCVVVSGDLPITITW----QKDGRPI 389
Query: 222 EETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ + L I + G + C N + LIV P +P
Sbjct: 390 PGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPR 449
Query: 282 VLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP-------NERIEILEDGLRLHIKNT 334
+ L+C G+P+ + W + P N RI++L +G L IK+
Sbjct: 450 DQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLL-IKHV 508
Query: 335 HKDDQGIYQCFASNARDQAYGMSEYL 360
++D G Y C SN S YL
Sbjct: 509 VEEDSGYYLCKVSNDVGADVSKSMYL 534
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
S +I EP R+ + +D+ LPC P P +W + + TP
Sbjct: 1025 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNG--TP-SL 1081
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
T+ R + G I+ V+ ED+G + C NN GS+ + L V P
Sbjct: 1082 VTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP 1131
Score = 39.1 bits (87), Expect = 0.024
Identities = 57/253 (22%), Positives = 107/253 (42%), Gaps = 30/253 (11%)
Query: 106 WLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSH 165
WL D N+ L ++ + G L I + SD + ++C V + R ++
Sbjct: 10 WLKD---NMPLELSGRFQKTVTG-LLIENIRPSDSGS-YVCEVSN-----RYGTAKVIGR 59
Query: 166 VIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT 225
+ V +P + ++ R + VG V L C+V W+ + E L P +
Sbjct: 60 LYVKQPL-----KATISPRKVKSSVGSQVSLSCSVTGTEDQELSWY-RNGEILNPGKNVR 113
Query: 226 LWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVRTKPEVL 283
+ + E L+ V+ D G + C++ S + +++ + P + E +
Sbjct: 114 I---TGINHENLIMDHMVK-SDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV 169
Query: 284 RSKPKSDIALDCKVNGHPIELVYW-LHNGRTLEP-NERIE--ILEDG---LRLHIKNTHK 336
S P ++L C V G P+ + W L + L+ + RI I +G L+I ++
Sbjct: 170 VS-PAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQV 228
Query: 337 DDQGIYQCFASNA 349
D G+Y+C A+N+
Sbjct: 229 RDGGVYRCTANNS 241
Score = 33.1 bits (72), Expect = 1.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL--HNG--RTLEP 316
SE + + P + T + + DI L CK G P V W+ NG +
Sbjct: 1025 SEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTI 1084
Query: 317 NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R I +G + I+ +D G Y C A+N
Sbjct: 1085 DGRRSIFSNGSFI-IRTVKAEDSGYYSCIANN 1115
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 69.7 bits (163), Expect = 1e-11
Identities = 69/274 (25%), Positives = 113/274 (41%), Gaps = 24/274 (8%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISAVS 136
D V +GN V C + I WL N++++++ S+ + LDDG+L I
Sbjct: 271 DADVTSGNTVYFTCRAEGNPKPEII---WLRNNNELSMK--TDSRLNLLDDGTLMIQNTQ 325
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
+D+ + C ++ ++T TL P +P ++ ++ + VG+ V L
Sbjct: 326 ETDQ-GIYQCMAKNVAGEVKTQEVTLR---YFGSP---ARPTFVIQPQNTEVLVGESVTL 378
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C+ P P W L P++ R + G L IQ V + D+G + C
Sbjct: 379 ECSATGHPPPRISWTRGDRTPL-PVDP-----RVNITPSGGLYIQNVVQGDSGEYACSAT 432
Query: 257 NTVGSESVHFT--LIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N + +SVH T +IV P+ + C+ G+P ++ W G L
Sbjct: 433 NNI--DSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 490
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R +L G L I DQG Y+C A N
Sbjct: 491 SVDRRHLVLSSG-TLRISGVALHDQGQYECQAVN 523
Score = 67.3 bits (157), Expect = 8e-11
Identities = 50/185 (27%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
+PR++ E + + G V C P P W ++E + R LLD+
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS-----RLNLLDD 316
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTL----IVTEPISVRTKPEVLRSKPKSD 290
G L IQ + D G + C N G ++ TL P V +P+
Sbjct: 317 GTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFV-IQPQNTEVLVGES 375
Query: 291 IALDCKVNGHPIELVYWLHNGRT-LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ L+C GHP + W RT L + R+ I G L+I+N + D G Y C A+N
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSG-GLYIQNVVQGDSGEYACSATNN 434
Query: 350 RDQAY 354
D +
Sbjct: 435 IDSVH 439
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/350 (22%), Positives = 133/350 (38%), Gaps = 34/350 (9%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK-N 61
WL+++N +L +G+L I + +Y+C ++ G + +
Sbjct: 296 WLRNNNELSMKTDSRLNLLDDGTLMIQN------TQETDQGIYQCMAKNVAGEVKTQEVT 349
Query: 62 IHVYAALSSPWEVHVPDEY-VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
+ + + + P V P V+ G +V L C H RIS W D + +
Sbjct: 350 LRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRIS---WTRGDRTPLP--VDP 404
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+ + G LYI V D + C + I + +V + P+ +
Sbjct: 405 RVNITPSGGLYIQNVVQGDS-GEYACSATNNIDSVHATAFIIVQAL----------PQFT 453
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
V + R + GQ V C P P W + QL+ + +R +L G L I
Sbjct: 454 VTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT-KGGSQLS------VDRRHLVLSSGTLRI 506
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDIALDCKVN 298
V D G++ C N +GS+ V L V ++ + P + +++ L C
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQ 566
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P + W +G + + + I +G L I + D G Y+C A N
Sbjct: 567 GEPEPAITWNKDGVQVTESGKFHISPEGF-LTINDVGPADAGRYECVARN 615
Score = 56.8 bits (131), Expect = 1e-07
Identities = 65/255 (25%), Positives = 111/255 (43%), Gaps = 25/255 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C +++ + + I V A + V D VI G V +C + I+ T
Sbjct: 427 YACSATNNIDSVHATAFIIVQAL--PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT 484
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ + ++ H + L G+L IS V+ D+ ++ C+ + I + +V+
Sbjct: 485 KGGSQLSVDRRHLV------LSSGTLRISGVALHDQ-GQYECQAVNIIGSQK-----VVA 532
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ V +P+ V P + + VG +V+LPC+ P P W ++ + E+
Sbjct: 533 HLTV-QPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW----NKDGVQVTES 585
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVL 283
+ + EG L+I V DAGR+ C NT+GS SV L V P +S P V
Sbjct: 586 G---KFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVA 642
Query: 284 RSKPKSDIALDCKVN 298
S ++ +D +N
Sbjct: 643 TSIVEAIATVDRAIN 657
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 69.7 bits (163), Expect = 1e-11
Identities = 69/274 (25%), Positives = 113/274 (41%), Gaps = 24/274 (8%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISAVS 136
D V +GN V C + I WL N++++++ S+ + LDDG+L I
Sbjct: 249 DADVTSGNTVYFTCRAEGNPKPEII---WLRNNNELSMK--TDSRLNLLDDGTLMIQNTQ 303
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
+D+ + C ++ ++T TL P +P ++ ++ + VG+ V L
Sbjct: 304 ETDQ-GIYQCMAKNVAGEVKTQEVTLR---YFGSP---ARPTFVIQPQNTEVLVGESVTL 356
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C+ P P W L P++ R + G L IQ V + D+G + C
Sbjct: 357 ECSATGHPPPRISWTRGDRTPL-PVDP-----RVNITPSGGLYIQNVVQGDSGEYACSAT 410
Query: 257 NTVGSESVHFT--LIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N + +SVH T +IV P+ + C+ G+P ++ W G L
Sbjct: 411 NNI--DSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 468
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R +L G L I DQG Y+C A N
Sbjct: 469 SVDRRHLVLSSG-TLRISGVALHDQGQYECQAVN 501
Score = 67.3 bits (157), Expect = 8e-11
Identities = 50/185 (27%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
+PR++ E + + G V C P P W ++E + R LLD+
Sbjct: 240 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS-----RLNLLDD 294
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTL----IVTEPISVRTKPEVLRSKPKSD 290
G L IQ + D G + C N G ++ TL P V +P+
Sbjct: 295 GTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFV-IQPQNTEVLVGES 353
Query: 291 IALDCKVNGHPIELVYWLHNGRT-LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ L+C GHP + W RT L + R+ I G L+I+N + D G Y C A+N
Sbjct: 354 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSG-GLYIQNVVQGDSGEYACSATNN 412
Query: 350 RDQAY 354
D +
Sbjct: 413 IDSVH 417
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/350 (22%), Positives = 133/350 (38%), Gaps = 34/350 (9%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK-N 61
WL+++N +L +G+L I + +Y+C ++ G + +
Sbjct: 274 WLRNNNELSMKTDSRLNLLDDGTLMIQN------TQETDQGIYQCMAKNVAGEVKTQEVT 327
Query: 62 IHVYAALSSPWEVHVPDEY-VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
+ + + + P V P V+ G +V L C H RIS W D + +
Sbjct: 328 LRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRIS---WTRGDRTPLP--VDP 382
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+ + G LYI V D + C + I + +V + P+ +
Sbjct: 383 RVNITPSGGLYIQNVVQGDS-GEYACSATNNIDSVHATAFIIVQAL----------PQFT 431
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
V + R + GQ V C P P W + QL+ + +R +L G L I
Sbjct: 432 VTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT-KGGSQLS------VDRRHLVLSSGTLRI 484
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDIALDCKVN 298
V D G++ C N +GS+ V L V ++ + P + +++ L C
Sbjct: 485 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQ 544
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P + W +G + + + I +G L I + D G Y+C A N
Sbjct: 545 GEPEPAITWNKDGVQVTESGKFHISPEGF-LTINDVGPADAGRYECVARN 593
Score = 56.8 bits (131), Expect = 1e-07
Identities = 65/255 (25%), Positives = 111/255 (43%), Gaps = 25/255 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C +++ + + I V A + V D VI G V +C + I+ T
Sbjct: 405 YACSATNNIDSVHATAFIIVQAL--PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT 462
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ + ++ H + L G+L IS V+ D+ ++ C+ + I + +V+
Sbjct: 463 KGGSQLSVDRRHLV------LSSGTLRISGVALHDQ-GQYECQAVNIIGSQK-----VVA 510
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ V +P+ V P + + VG +V+LPC+ P P W ++ + E+
Sbjct: 511 HLTV-QPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW----NKDGVQVTES 563
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVL 283
+ + EG L+I V DAGR+ C NT+GS SV L V P +S P V
Sbjct: 564 G---KFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVA 620
Query: 284 RSKPKSDIALDCKVN 298
S ++ +D +N
Sbjct: 621 TSIVEAIATVDRAIN 635
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 69.7 bits (163), Expect = 1e-11
Identities = 69/274 (25%), Positives = 113/274 (41%), Gaps = 24/274 (8%)
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWL-NDDDINVLHYLGSKYHRLDDGSLYISAVS 136
D V +GN V C + I WL N++++++ S+ + LDDG+L I
Sbjct: 271 DADVTSGNTVYFTCRAEGNPKPEII---WLRNNNELSMK--TDSRLNLLDDGTLMIQNTQ 325
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
+D+ + C ++ ++T TL P +P ++ ++ + VG+ V L
Sbjct: 326 ETDQ-GIYQCMAKNVAGEVKTQEVTLR---YFGSP---ARPTFVIQPQNTEVLVGESVTL 378
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C+ P P W L P++ R + G L IQ V + D+G + C
Sbjct: 379 ECSATGHPPPRISWTRGDRTPL-PVDP-----RVNITPSGGLYIQNVVQGDSGEYACSAT 432
Query: 257 NTVGSESVHFT--LIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N + +SVH T +IV P+ + C+ G+P ++ W G L
Sbjct: 433 NNI--DSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQL 490
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ R +L G L I DQG Y+C A N
Sbjct: 491 SVDRRHLVLSSG-TLRISGVALHDQGQYECQAVN 523
Score = 67.3 bits (157), Expect = 8e-11
Identities = 50/185 (27%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
+PR++ E + + G V C P P W ++E + R LLD+
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS-----RLNLLDD 316
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTL----IVTEPISVRTKPEVLRSKPKSD 290
G L IQ + D G + C N G ++ TL P V +P+
Sbjct: 317 GTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFV-IQPQNTEVLVGES 375
Query: 291 IALDCKVNGHPIELVYWLHNGRT-LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ L+C GHP + W RT L + R+ I G L+I+N + D G Y C A+N
Sbjct: 376 VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSG-GLYIQNVVQGDSGEYACSATNN 434
Query: 350 RDQAY 354
D +
Sbjct: 435 IDSVH 439
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/350 (22%), Positives = 133/350 (38%), Gaps = 34/350 (9%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK-N 61
WL+++N +L +G+L I + +Y+C ++ G + +
Sbjct: 296 WLRNNNELSMKTDSRLNLLDDGTLMIQN------TQETDQGIYQCMAKNVAGEVKTQEVT 349
Query: 62 IHVYAALSSPWEVHVPDEY-VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
+ + + + P V P V+ G +V L C H RIS W D + +
Sbjct: 350 LRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRIS---WTRGDRTPLP--VDP 404
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+ + G LYI V D + C + I + +V + P+ +
Sbjct: 405 RVNITPSGGLYIQNVVQGDS-GEYACSATNNIDSVHATAFIIVQAL----------PQFT 453
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
V + R + GQ V C P P W + QL+ + +R +L G L I
Sbjct: 454 VTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT-KGGSQLS------VDRRHLVLSSGTLRI 506
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDIALDCKVN 298
V D G++ C N +GS+ V L V ++ + P + +++ L C
Sbjct: 507 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQ 566
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
G P + W +G + + + I +G L I + D G Y+C A N
Sbjct: 567 GEPEPAITWNKDGVQVTESGKFHISPEGF-LTINDVGPADAGRYECVARN 615
Score = 56.8 bits (131), Expect = 1e-07
Identities = 65/255 (25%), Positives = 111/255 (43%), Gaps = 25/255 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C +++ + + I V A + V D VI G V +C + I+ T
Sbjct: 427 YACSATNNIDSVHATAFIIVQAL--PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT 484
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ + ++ H + L G+L IS V+ D+ ++ C+ + I + +V+
Sbjct: 485 KGGSQLSVDRRHLV------LSSGTLRISGVALHDQ-GQYECQAVNIIGSQK-----VVA 532
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ V +P+ V P + + VG +V+LPC+ P P W ++ + E+
Sbjct: 533 HLTV-QPR--VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW----NKDGVQVTES 585
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVL 283
+ + EG L+I V DAGR+ C NT+GS SV L V P +S P V
Sbjct: 586 G---KFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVA 642
Query: 284 RSKPKSDIALDCKVN 298
S ++ +D +N
Sbjct: 643 TSIVEAIATVDRAIN 657
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 69.3 bits (162), Expect = 2e-11
Identities = 62/274 (22%), Positives = 125/274 (45%), Gaps = 24/274 (8%)
Query: 84 GNAVVLRCVVPPHCADRISSTEWLNDDDINVLH--YLGSKYHRLDDGSLYISAVSTSDRH 141
G+ V L C V + I +W D++ + + S +L G+L+I + SD+
Sbjct: 148 GSNVTLPCYVQGYPEPTI---KWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDK- 203
Query: 142 NRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVH 201
++C ++ I++ V+ ++ P G+ P V+ + GQ + LPC +
Sbjct: 204 GTYICEAENQFGKIQSETTVTVTGLVA--PLIGISPSVA------NVIEGQQLTLPCTLL 255
Query: 202 AW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
A P+P RW ++ L ++ + R+ +G L I++V+ +D G + C +N G
Sbjct: 256 AGNPIPERRWI-KNSAML--LQNPYITVRS----DGSLHIERVQLQDGGEYTCVASNVAG 308
Query: 261 SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNE-R 319
+ + +++V +++ ++L + + L CK +G+P V W G + + +
Sbjct: 309 TNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK 368
Query: 320 IEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
DG L++ + ++ G Y C A+N A
Sbjct: 369 FSAGADG-SLYVVSPGGEESGEYVCTATNTAGYA 401
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 6/178 (3%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P E + +G +V LPC V +P PT +W + + L
Sbjct: 131 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 188
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS--VRTKPEVLRSKPKSDI 291
G L I + D G ++C N G T+ VT ++ + P V +
Sbjct: 189 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQL 248
Query: 292 ALDCK-VNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L C + G+PI W+ N L N I + DG LHI+ D G Y C ASN
Sbjct: 249 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASN 305
Score = 61.3 bits (142), Expect = 5e-09
Identities = 87/360 (24%), Positives = 136/360 (37%), Gaps = 45/360 (12%)
Query: 3 WLQSDNTPVAS----LSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAM 58
W + DN P+ S +S + Q L+ G+L IL L+ D Y C + G I
Sbjct: 167 WRRLDNMPIFSRPFSVSSISQ-LRTGALFIL----NLWASD--KGTYICEAENQFGKIQS 219
Query: 59 SKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ V ++ + VI G + L C + + I W+ N L
Sbjct: 220 ETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLL--AGNPIPERRWIK----NSAMLL 273
Query: 119 GSKYHRL-DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKP 177
+ Y + DGSL+I V D + C V + G ++V HV+ T G
Sbjct: 274 QNPYITVRSDGSLHIERVQLQDG-GEYTC-VASNVAGTNNKTTSVVVHVLPTIQHG---- 327
Query: 178 RVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL 237
Q+ G V LPC P P+ W + + T+ K + D G
Sbjct: 328 -----QQILSTIEGIPVTLPCKASGNPKPSVIW-----SKKGELISTSSAKFSAGAD-GS 376
Query: 238 LSIQKVRREDAGRFVCWLNNTVG--SESVHFTLIVTEPIS------VRTKPEVLRSKPKS 289
L + E++G +VC NT G V T+ V + + KP +
Sbjct: 377 LYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGE 436
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEP-NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
++ L C+V P ++ W + + P + R L G + I T D G+Y C A+N
Sbjct: 437 EVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-SMKITETRTSDSGMYLCVATN 495
Score = 52.0 bits (119), Expect = 3e-06
Identities = 52/178 (29%), Positives = 74/178 (41%), Gaps = 14/178 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
P++ V Q + +G + C P P +WF + +L P +T LL G
Sbjct: 43 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWF-KGDLELRP---STFLIIDPLL--G 96
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCK 296
LL IQ+ + DAG + C N G + TL V P +P + + S++ L C
Sbjct: 97 LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCY 156
Query: 297 VNGHPIELVYW--LHN----GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V G+P + W L N R + I L G L I N D+G Y C A N
Sbjct: 157 VQGYPEPTIKWRRLDNMPIFSRPFSVSS-ISQLRTG-ALFILNLWASDKGTYICEAEN 212
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Query: 232 LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDI 291
+ +G L I+ +DAG + C +N+ G++ + TL E + L
Sbjct: 1 MTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDIT 60
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRL-HIKNTHKDDQGIYQCFASNAR 350
++CK +G P V W L P+ + I++ L L I+ T D G Y C A N
Sbjct: 61 VMECKTSGIPPPQVKWFKGDLELRPSTFL-IIDPLLGLLKIQETQDLDAGDYTCVAINEA 119
Query: 351 DQAYG 355
+A G
Sbjct: 120 GRATG 124
Score = 38.7 bits (86), Expect = 0.032
Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 11/143 (7%)
Query: 120 SKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN-TLVSHVIVTEPKGGVKPR 178
+K+ DGSLY+ + + ++C + + V T+ V + G+
Sbjct: 367 AKFSAGADGSLYVVSPG-GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD 425
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
VE + G++V LPC V + P P W E + ++P R L G +
Sbjct: 426 KPVEIS---VLAGEEVTLPCEVKSLPPPIITWAKE-TQLISPFS-----PRHTFLPSGSM 476
Query: 239 SIQKVRREDAGRFVCWLNNTVGS 261
I + R D+G ++C N G+
Sbjct: 477 KITETRTSDSGMYLCVATNIAGN 499
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 69.3 bits (162), Expect = 2e-11
Identities = 58/228 (25%), Positives = 89/228 (39%), Gaps = 15/228 (6%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQ--- 183
+G LY S V D + C R T N V+ T P Q
Sbjct: 2 NGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTA 61
Query: 184 RSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKV 243
S+ + G D+ L C P P W+ + + + + + +A L I V
Sbjct: 62 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKA-------LRITNV 114
Query: 244 RREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIE 303
ED+G + C +N +GS ++ V +P+ L P D L C+ NG+P
Sbjct: 115 SEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKP 174
Query: 304 LVYWLHNGRTLE---PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
V W+ NG L+ PN E+ D + ++T + +YQC SN
Sbjct: 175 TVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSN 220
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 236 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 288
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 289 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 348
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 349 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 406
Query: 351 DQ 352
DQ
Sbjct: 407 DQ 408
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 108 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 156
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 157 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 211
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 212 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 271
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 272 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 318
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 68.9 bits (161), Expect = 3e-11
Identities = 81/318 (25%), Positives = 126/318 (39%), Gaps = 23/318 (7%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 115 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRT 157
I W+ D+ L L+ G LY S V D ++C R T
Sbjct: 174 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 229
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEH 214
+ VI + P + + + G + L C P P W E
Sbjct: 230 QKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE- 288
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+ + P + T++K E L I V D+G + C N +G+ +H T+ V
Sbjct: 289 -DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCIAKNALGA--IHHTISVRVKA 340
Query: 275 SVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLH 330
+ T P+ L P D L C+ NG+P + WL NG +E P++ + DG +
Sbjct: 341 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI-DGDTII 399
Query: 331 IKNTHKDDQGIYQCFASN 348
N + +YQC ASN
Sbjct: 400 FSNVQERSSAVYQCNASN 417
Score = 61.3 bits (142), Expect = 5e-09
Identities = 74/312 (23%), Positives = 134/312 (42%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 319 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 374
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 375 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 427
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 428 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 474
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + + + +PE
Sbjct: 475 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 534
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 535 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 592
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 593 GTYTCVANTTLD 604
Score = 36.3 bits (80), Expect = 0.17
Identities = 53/237 (22%), Positives = 93/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 408 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 461
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 462 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 518
Query: 159 VNTLVSHV--IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHE 216
V+ + IV +P+ V R S+ +++ + L T W ++ E
Sbjct: 519 VHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSL----------TVLWLKDNRE 568
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
P +E +D+ L + V +D+G + C N T+ S S L V P
Sbjct: 569 --LPSDERFT------VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 617
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 269 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 326
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAA 132
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 68.9 bits (161), Expect = 3e-11
Identities = 81/318 (25%), Positives = 126/318 (39%), Gaps = 23/318 (7%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 115 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRT 157
I W+ D+ L L+ G LY S V D ++C R T
Sbjct: 174 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 229
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEH 214
+ VI + P + + + G + L C P P W E
Sbjct: 230 QKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE- 288
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+ + P + T++K E L I V D+G + C N +G+ +H T+ V
Sbjct: 289 -DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCIAKNALGA--IHHTISVRVKA 340
Query: 275 SVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLH 330
+ T P+ L P D L C+ NG+P + WL NG +E P++ + DG +
Sbjct: 341 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI-DGDTII 399
Query: 331 IKNTHKDDQGIYQCFASN 348
N + +YQC ASN
Sbjct: 400 FSNVQERSSAVYQCNASN 417
Score = 61.3 bits (142), Expect = 5e-09
Identities = 74/312 (23%), Positives = 134/312 (42%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 319 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 374
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 375 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 427
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 428 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 474
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + + + +PE
Sbjct: 475 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 534
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 535 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 592
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 593 GTYTCVANTTLD 604
Score = 36.3 bits (80), Expect = 0.17
Identities = 53/237 (22%), Positives = 93/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 408 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 461
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 462 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 518
Query: 159 VNTLVSHV--IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHE 216
V+ + IV +P+ V R S+ +++ + L T W ++ E
Sbjct: 519 VHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSL----------TVLWLKDNRE 568
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
P +E +D+ L + V +D+G + C N T+ S S L V P
Sbjct: 569 --LPSDERFT------VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 617
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 269 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 326
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAA 132
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 68.9 bits (161), Expect = 3e-11
Identities = 81/318 (25%), Positives = 126/318 (39%), Gaps = 23/318 (7%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 122 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 180
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRT 157
I W+ D+ L L+ G LY S V D ++C R T
Sbjct: 181 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 236
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEH 214
+ VI + P + + + G + L C P P W E
Sbjct: 237 QKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE- 295
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+ + P + T++K E L I V D+G + C N +G+ +H T+ V
Sbjct: 296 -DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCIAKNALGA--IHHTISVRVKA 347
Query: 275 SVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE--PNERIEILEDGLRLH 330
+ T P+ L P D L C+ NG+P + WL NG +E P++ + DG +
Sbjct: 348 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI-DGDTII 406
Query: 331 IKNTHKDDQGIYQCFASN 348
N + +YQC ASN
Sbjct: 407 FSNVQERSSAVYQCNASN 424
Score = 61.3 bits (142), Expect = 5e-09
Identities = 74/312 (23%), Positives = 134/312 (42%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 326 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 381
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 382 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 434
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 435 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 481
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + + + +PE
Sbjct: 482 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 541
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 542 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 599
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 600 GTYTCVANTTLD 611
Score = 36.3 bits (80), Expect = 0.17
Identities = 53/237 (22%), Positives = 93/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 415 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 468
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 469 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 525
Query: 159 VNTLVSHV--IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHE 216
V+ + IV +P+ V R S+ +++ + L T W ++ E
Sbjct: 526 VHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSL----------TVLWLKDNRE 575
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
P +E +D+ L + V +D+G + C N T+ S S L V P
Sbjct: 576 --LPSDERFT------VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 624
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 276 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 333
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 49 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 108
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 109 GTLIINIMSEGKAETYEGVYQCTARNERGAA 139
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 68.5 bits (160), Expect = 3e-11
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 12/183 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
P+ + +S+ ++ Q V+ C V P P WF E +++ A
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENA---GSH 470
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE---VLRSKPK---SD 290
L + K R D+G + C +N G S +TL V + P VL+ D
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL-RLHIKNTHKDDQGIYQCFASNA 349
L C V G P+ + WL NG+ ++ E G+ LHI++ +D G Y C A NA
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 350 RDQ 352
Q
Sbjct: 589 LGQ 591
Score = 54.8 bits (126), Expect = 5e-07
Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 28/196 (14%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
V P S + + GQD L C+V PVP W PI+ A + +
Sbjct: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ----PIQYARSTCEAGVAE 567
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL---RSKPK--- 288
L IQ ED G + C N +G S + V E S R +L SKP
Sbjct: 568 ---LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
Query: 289 -------------SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKN 333
S + + +V+G+P V WLHNG ++ +E + G + L I+
Sbjct: 625 FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
Query: 334 THKDDQGIYQCFASNA 349
+D G Y C A N+
Sbjct: 685 VFPEDTGTYTCEAWNS 700
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + V P P W +E I+E+ + + + L IQ+V E
Sbjct: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNE----IQESEDFHFEQRGTQHSLCIQEVFPE 688
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKS-------DIALDCKVNG 299
D G + C N+ G L V EP T+P + SKP+S + + C + G
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEPHD-GTQPWFI-SKPRSVTASLGQSVLISCAIAG 746
Query: 300 HPIELVYWLHNGRTL-EPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
P V+WL +G+ L + E+L ED L +K G Y+ N
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILE-DGLR-LHIKNTHKDDQGIYQCFASNARDQ 352
CK+ G P V WL L+P+ R+ + E +G++ L I ++DD G+Y C N +
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
Query: 353 AYGMSEYLFDG 363
A +E G
Sbjct: 242 ASMSAELSIQG 252
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASN 348
+ L C+V+ P + W NG+TL+ + I + ++G + I+ +D+G+Y+C A N
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 349 ARDQA 353
QA
Sbjct: 1175 DAGQA 1179
Score = 41.5 bits (93), Expect = 0.005
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V EP G +P + RS +GQ V + CA+ P PT W + ++T +
Sbjct: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL---RDGKALCKDTGHF 768
Query: 228 KRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + D L ++KV+ AG++ L N VG S +L++ + S R P
Sbjct: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML-QNSSARALP 820
Score = 36.3 bits (80), Expect = 0.17
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 270 VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR- 328
+TE + P L K + + +V G+P V W NG+ + R +L+ G+R
Sbjct: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRG 87
Query: 329 ---LHIKNTHKDDQGIYQCFASN 348
L I H++D+G Y C A+N
Sbjct: 88 TFSLVIHAVHEEDRGKYTCEATN 110
Score = 35.1 bits (77), Expect = 0.39
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDG-LRLHIKNTHKDDQGIYQCFASNAR 350
DCK+ G+P V W + +++ + +I+ EDG L I + DD Y C A N+
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888
Query: 351 DQAYGMSEYLFD 362
+A +E + +
Sbjct: 1889 GEATCTAELIVE 1900
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P + + + G+ + L C V + P T W + + L + L + L
Sbjct: 1095 GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLC 1153
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE-PISVRTK-PEVLRSKPKSDI 291
+SI+K ED G + C N G + V + P S TK PE+ +PKS +
Sbjct: 1154 S---VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
Score = 31.9 bits (69), Expect = 3.7
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 169 TEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK 228
T PK + P++ +++R G+ V L V T W + +Q I+E+ K
Sbjct: 1230 TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW-MKFRKQ---IQESEHMK 1285
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
+ L+I R+E G + + N +GS L V +
Sbjct: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
Score = 31.9 bits (69), Expect = 3.7
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 5/104 (4%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V E K VKP S R + G R C + +P P WF + I E+ +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS----IRESRHF 1855
Query: 228 KRARLLDEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ D L I V +D ++ C N++G + LIV
Sbjct: 1856 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 68.1 bits (159), Expect = 5e-11
Identities = 51/170 (30%), Positives = 74/170 (43%), Gaps = 14/170 (8%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DEGLLSIQKVRREDAG 249
G V++ C PVPT W + + +ARL + +L I V+ +DAG
Sbjct: 21 GTTVKMECFALGNPVPTITWMKVNGY---------IPSKARLRKSQAVLEIPNVQLDDAG 71
Query: 250 RFVCWLNNTVGSESVHFTL-IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
+ C N+ G S L + T P V K + S + +CK G P WL
Sbjct: 72 IYECRAENSRGKNSFRGQLQVYTYPHWVE-KLNDTQLDSGSPLRWECKATGKPRPTYRWL 130
Query: 309 HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
NG L P R+E++ L +H N ++ D G+YQC A N Y +E
Sbjct: 131 KNGVPLSPQSRVEMVNGVLMIH--NVNQSDAGMYQCLAENKYGAIYASAE 178
Score = 51.2 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 17/197 (8%)
Query: 177 PRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
P ++ Q + I V Q+V + C P PT W + + E KR +L
Sbjct: 186 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISW----KKGDRAVREN---KRIAILP 238
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD 294
+G L I + D G++VC N GS + +L V EP + P+ I L+
Sbjct: 239 DGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLN 298
Query: 295 CK-VNGHPIELV-YWLHNGRTLEPNER------IEILEDGLRLHIKNTHKDDQGIYQCFA 346
CK ++ +++ YW G+ ++ E I L I+N G Y C
Sbjct: 299 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 358
Query: 347 SNARDQAYGMSEYLFDG 363
D +E L G
Sbjct: 359 QTTADSVSDEAELLVRG 375
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 67.7 bits (158), Expect = 6e-11
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 12/183 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
P+ + +S+ ++ Q V+ C V P P WF E +++ A
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA---GSH 470
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE---VLRSKPK---SD 290
L + K R D+G + C +N G S +TL V + P VL+ D
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL-RLHIKNTHKDDQGIYQCFASNA 349
L C V G P+ + WL NG+ ++ E G+ LHI++ +D G Y C A NA
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 350 RDQ 352
Q
Sbjct: 589 LGQ 591
Score = 56.0 bits (129), Expect = 2e-07
Identities = 63/246 (25%), Positives = 94/246 (38%), Gaps = 33/246 (13%)
Query: 126 DDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
D GS Y+ + R + + C + + + V + V E V P S +
Sbjct: 466 DAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME----VAPSFSSVLK 521
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ GQD L C+V PVP W PI+ A + + L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ----PIQYARSTCEAGVAE---LHIQDAL 574
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL---RSKPK------------- 288
ED G + C N +G S + V E S R +L SKP
Sbjct: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
Query: 289 ---SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQ 343
S + + +V+G+P V WLHNG ++ +E + G + L I+ +D G Y
Sbjct: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYT 694
Query: 344 CFASNA 349
C A N+
Sbjct: 695 CEAWNS 700
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + V P P W +E I+E+ + + + L IQ+V E
Sbjct: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNE----IQESEDFHFEQRGTQHSLWIQEVFPE 688
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKS-------DIALDCKVNG 299
D G + C N+ G L V EP T+P + SKP+S + + C + G
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEPHD-GTQPWFI-SKPRSVTASLGQSVLISCAIAG 746
Query: 300 HPIELVYWLHNGRTL-EPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
P V+WL +G+ L + E+L ED L +K G Y+ N
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILE-DGLR-LHIKNTHKDDQGIYQCFASNARDQ 352
CK+ G P V WL L+P+ R+ + E +G++ L I ++DD G+Y C N +
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
Query: 353 AYGMSEYLFDG 363
A +E G
Sbjct: 242 ASMSAELSIQG 252
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASN 348
+ L C+V+ P + W NG+TL+ + I + ++G + I+ +D+G+Y+C A N
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 349 ARDQA 353
QA
Sbjct: 1175 DAGQA 1179
Score = 42.3 bits (95), Expect = 0.003
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
SL+I V D + C + +RT + + V EP G +P + RS
Sbjct: 679 SLWIQEVFPEDT-GTYTCEAWNSAGEVRTQ-----AVLTVQEPHDGTQPWFISKPRSVTA 732
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
+GQ V + CA+ P PT W + ++T ++ + D L ++KV+ A
Sbjct: 733 SLGQSVLISCAIAGDPFPTVHWL---RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
G++ L N VG S +L++ + S R P
Sbjct: 790 GQYEILLKNRVGECSCQVSLML-QNSSARALP 820
Score = 36.3 bits (80), Expect = 0.17
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 270 VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR- 328
+TE + P L K + + +V G+P V W NG+ + R +L+ G+R
Sbjct: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRG 87
Query: 329 ---LHIKNTHKDDQGIYQCFASN 348
L I H++D+G Y C A+N
Sbjct: 88 TFSLVIHAVHEEDRGKYTCEATN 110
Score = 35.1 bits (77), Expect = 0.39
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDG-LRLHIKNTHKDDQGIYQCFASNAR 350
DCK+ G+P V W + +++ + +I+ EDG L I + DD Y C A N+
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888
Query: 351 DQAYGMSEYLFD 362
+A +E + +
Sbjct: 1889 GEATCTAELIVE 1900
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P + + + G+ + L C V + P T W + + L + L + L
Sbjct: 1095 GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLC 1153
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE-PISVRTK-PEVLRSKPKSDI 291
+SI+K ED G + C N G + V + P S TK PE+ +PKS +
Sbjct: 1154 S---VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
Score = 31.9 bits (69), Expect = 3.7
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 169 TEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK 228
T PK + P++ +++R G+ V L V T W + +Q I+E+ K
Sbjct: 1230 TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW-MKFRKQ---IQESEHMK 1285
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
+ L+I R+E G + + N +GS L V +
Sbjct: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
Score = 31.9 bits (69), Expect = 3.7
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 5/104 (4%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V E K VKP S R + G R C + +P P WF + I E+ +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS----IRESRHF 1855
Query: 228 KRARLLDEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ D L I V +D ++ C N++G + LIV
Sbjct: 1856 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 103 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 155
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 156 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 215
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 216 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 273
Query: 351 DQ 352
DQ
Sbjct: 274 DQ 275
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 9/175 (5%)
Query: 182 EQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
E ++ + G+D RL C + P PT +W P++ + + ++ +
Sbjct: 17 EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FR 71
Query: 242 KVRREDAGRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
+ + C +N G + +++ P + + +++R + LDC G
Sbjct: 72 DTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFG 131
Query: 300 HPIELVYWLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
PI + W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 132 SPIPTLRWFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 185
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 67.7 bits (158), Expect = 6e-11
Identities = 48/162 (29%), Positives = 67/162 (41%), Gaps = 5/162 (3%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DEGLLSIQKVRRE 246
IR RL CA P P W + E +R ++ D+ + I V+ +
Sbjct: 610 IRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARE----RRMHVMPDDDVFFITDVKID 665
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
DAG + C N+ GS S + TL V E S+ E +AL CK G+P +
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRIT 725
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
W R L ER + D L ++N +D G Y C SN
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 767
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/186 (25%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPC-AVHAWPVP-TYRWFFEHHEQLTPIE-ETTLWKRAR 231
+KP++ + + VG+D+R C A + P T+ W + +E LT + E + A+
Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWK-KDNEVLTNADMENFVHVHAQ 551
Query: 232 ----LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK-PEVLRSK 286
+ +L +++V GR+ C + N GS H + + TK P + +
Sbjct: 552 DGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIR 611
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGRTLEP---NERIEILEDGLRLHIKNTHKDDQGIYQ 343
+ L+C GHP + W +G T P R+ ++ D I + DD G+Y
Sbjct: 612 TTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYS 671
Query: 344 CFASNA 349
C A N+
Sbjct: 672 CTAQNS 677
Score = 50.4 bits (115), Expect = 1e-05
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P + V R + VG+ V L C P P WF P+ +L +R L D
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDR----PL---SLTERHHLTPDN 745
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
LL +Q V EDAGR+ C ++NT+G+E H L V
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 67.7 bits (158), Expect = 6e-11
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 12/183 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
P+ + +S+ ++ Q V+ C V P P WF E +++ A
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA---GSH 470
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE---VLRSKPK---SD 290
L + K R D+G + C +N G S +TL V + P VL+ D
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL-RLHIKNTHKDDQGIYQCFASNA 349
L C V G P+ + WL NG+ ++ E G+ LHI++ +D G Y C A NA
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 350 RDQ 352
Q
Sbjct: 589 LGQ 591
Score = 55.6 bits (128), Expect = 3e-07
Identities = 63/246 (25%), Positives = 94/246 (38%), Gaps = 33/246 (13%)
Query: 126 DDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
D GS Y+ + R + + C + + + V + V E V P S +
Sbjct: 466 DAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME----VAPSFSSVLK 521
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ GQD L C+V PVP W PI+ A + + L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ----PIQYARSTCEAGVAE---LHIQDAL 574
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL---RSKPK------------- 288
ED G + C N +G S + V E S R +L SKP
Sbjct: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
Query: 289 ---SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQ 343
S + + +V+G+P V WLHNG ++ +E + G + L I+ +D G Y
Sbjct: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
Query: 344 CFASNA 349
C A N+
Sbjct: 695 CEAWNS 700
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + V P P W +E I+E+ + + + L IQ+V E
Sbjct: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNE----IQESEDFHFEQRGTQHSLCIQEVFPE 688
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKS-------DIALDCKVNG 299
D G + C N+ G L V EP T+P + SKP+S + + C + G
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEPHD-GTQPWFI-SKPRSVTASLGQSVLISCAIAG 746
Query: 300 HPIELVYWLHNGRTL-EPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
P V+WL +G+ L + E+L ED L +K G Y+ N
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILE-DGLR-LHIKNTHKDDQGIYQCFASNARDQ 352
CK+ G P V WL L+P+ R+ + E +G++ L I ++DD G+Y C N +
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
Query: 353 AYGMSEYLFDG 363
A +E G
Sbjct: 242 ASMSAELSIQG 252
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASN 348
+ L C+V+ P + W NG+TL+ + I + ++G + I+ +D+G+Y+C A N
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 349 ARDQA 353
QA
Sbjct: 1175 DAGQA 1179
Score = 41.5 bits (93), Expect = 0.005
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V EP G +P + RS +GQ V + CA+ P PT W + ++T +
Sbjct: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL---RDGKALCKDTGHF 768
Query: 228 KRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
+ + D L ++KV+ AG++ L N VG S +L++ + S R P
Sbjct: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML-QNSSARALP 820
Score = 36.3 bits (80), Expect = 0.17
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 270 VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR- 328
+TE + P L K + + +V G+P V W NG+ + R +L+ G+R
Sbjct: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRG 87
Query: 329 ---LHIKNTHKDDQGIYQCFASN 348
L I H++D+G Y C A+N
Sbjct: 88 TFSLVIHAVHEEDRGKYTCEATN 110
Score = 35.1 bits (77), Expect = 0.39
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDG-LRLHIKNTHKDDQGIYQCFASNAR 350
DCK+ G+P V W + +++ + +I+ EDG L I + DD Y C A N+
Sbjct: 1829 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1888
Query: 351 DQAYGMSEYLFD 362
+A +E + +
Sbjct: 1889 GEATCTAELIVE 1900
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P + + + G+ + L C V + P T W + + L + L + L
Sbjct: 1095 GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLC 1153
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE-PISVRTK-PEVLRSKPKSDI 291
+SI+K ED G + C N G + V + P S TK PE+ +PKS +
Sbjct: 1154 S---VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
Score = 31.9 bits (69), Expect = 3.7
Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)
Query: 169 TEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK 228
T PK + P++ +++R G+ V L V T W + +Q I+E+ K
Sbjct: 1230 TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW-MKFRKQ---IQESEHMK 1285
Query: 229 RARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
+ L+I R+E G + + N +GS L V +
Sbjct: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
Score = 31.9 bits (69), Expect = 3.7
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 5/104 (4%)
Query: 168 VTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLW 227
V E K VKP S R + G R C + +P P WF + I E+ +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS----IRESRHF 1855
Query: 228 KRARLLDEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
+ D L I V +D ++ C N++G + LIV
Sbjct: 1856 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
>AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 67.7 bits (158), Expect = 6e-11
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 21/231 (9%)
Query: 127 DGSLYISAVSTSDRHNRFLCRVRDKITGIRTAV--NTLVSHVIVTEPKGGVKPRVSVEQR 184
+G+LY + V TSD H+ ++C G RT + + V T KPR+
Sbjct: 22 NGNLYFANVLTSDNHSDYICHAH--FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTN 79
Query: 185 SRRIRV---GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
S V GQ + L C +P PT +W P + T + L +
Sbjct: 80 SSSHLVALQGQPLVLECIAEGFPTPTIKWL--RPSGPMPADRVTYQNHNK-----TLQLL 132
Query: 242 KVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
KV ED G + C N++GS ++ + P + KP+ P LDC+V G
Sbjct: 133 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH-KPQSHLYGPGETARLDCQVQGR 191
Query: 301 PIELVYWLHNG---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P V W NG L +++ I L L N D + QC A N
Sbjct: 192 PQPEVTWRINGIPVEELAKDQKYRIQRGALIL--SNVQPSDTMVTQCEARN 240
Score = 61.7 bits (143), Expect = 4e-09
Identities = 75/325 (23%), Positives = 132/325 (40%), Gaps = 28/325 (8%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
YRC +S+G + + V AA P+ +H P ++ G L C V ++
Sbjct: 142 YRCLAENSLGSARHAYYVTVEAA---PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVT- 197
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W + I V + +R+ G+L +S V SD C R++ G+ A
Sbjct: 198 --W-RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEARNR-HGLLLAN---- 248
Query: 164 SHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEE 223
+++ V + + ++ + ++ G L C PVP+ +W E + T +++
Sbjct: 249 AYIYVVQLPAKI---LTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE--DGTTVLQD 303
Query: 224 TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL 283
+ A G L I+ ++ D GR+ C N + ++ L V + + P
Sbjct: 304 ERFFPYAN----GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 359
Query: 284 RSKPKSDIALDCKVNGHPI--ELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQ 339
K S + C+ + P + W +GR L+ + +EDG RL I + DQ
Sbjct: 360 IEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQ 418
Query: 340 GIYQCFASNARDQAYGMSEYLFDGN 364
G Y C AS D ++ L G+
Sbjct: 419 GNYSCVASTELDVVESRAQLLVVGS 443
Score = 34.3 bits (75), Expect = 0.69
Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L+C G P + WL + P +R+ L + ++D G Y+C A N+
Sbjct: 92 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 351 DQA 353
A
Sbjct: 151 GSA 153
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 415 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 467
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 468 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 527
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 528 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 585
Query: 351 DQ 352
DQ
Sbjct: 586 DQ 587
Score = 65.7 bits (153), Expect = 2e-10
Identities = 76/328 (23%), Positives = 121/328 (36%), Gaps = 38/328 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 86 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 144
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 145 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 200
Query: 164 SHVIVTEPKG--------------GVKPRVSV------EQRSRRIRVGQDVRLPCAVHAW 203
V+ P GV R S+ + G D+ L C
Sbjct: 201 LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 260
Query: 204 PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
P P W+ + + + + + +A L I V ED+G + C +N +GS
Sbjct: 261 PTPDIAWYKKGGDLPSDKAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIR 313
Query: 264 VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERI 320
++ V +P+ L P D L C+ NG+P V W+ NG L+ PN
Sbjct: 314 HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 373
Query: 321 EILEDGLRLHIKNTHKDDQGIYQCFASN 348
E+ D + ++T + +YQC SN
Sbjct: 374 EVAGD--TIIFRDTQISSRAVYQCNTSN 399
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 287 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 335
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 336 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 390
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 391 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 450
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 451 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 497
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 25 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 84
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 85 EYQCFARN 92
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 439 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 491
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 492 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 551
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 552 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 609
Query: 351 DQ 352
DQ
Sbjct: 610 DQ 611
Score = 65.7 bits (153), Expect = 2e-10
Identities = 76/328 (23%), Positives = 121/328 (36%), Gaps = 38/328 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 110 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 168
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 169 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 224
Query: 164 SHVIVTEPKG--------------GVKPRVSV------EQRSRRIRVGQDVRLPCAVHAW 203
V+ P GV R S+ + G D+ L C
Sbjct: 225 LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 284
Query: 204 PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
P P W+ + + + + + +A L I V ED+G + C +N +GS
Sbjct: 285 PTPDIAWYKKGGDLPSDKAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIR 337
Query: 264 VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERI 320
++ V +P+ L P D L C+ NG+P V W+ NG L+ PN
Sbjct: 338 HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 397
Query: 321 EILEDGLRLHIKNTHKDDQGIYQCFASN 348
E+ D + ++T + +YQC SN
Sbjct: 398 EVAGD--TIIFRDTQISSRAVYQCNTSN 423
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 311 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 359
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 360 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 414
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 475 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 521
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 49 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 108
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 109 EYQCFARN 116
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 67.7 bits (158), Expect = 6e-11
Identities = 48/161 (29%), Positives = 67/161 (41%), Gaps = 5/161 (3%)
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DEGLLSIQKVRRED 247
RV RL CA P P W + E +R ++ D+ + I V+ +D
Sbjct: 1 RVRTVARLECAATGHPNPQIAWQKDGGTDFPAARE----RRMHVMPDDDVFFITDVKIDD 56
Query: 248 AGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
AG + C N+ GS S + TL V E S+ E +AL CK G+P + W
Sbjct: 57 AGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITW 116
Query: 308 LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
R L ER + D L ++N +D G Y C SN
Sbjct: 117 FKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 157
Score = 50.4 bits (115), Expect = 1e-05
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P + V R + VG+ V L C P P WF P+ +L +R L D
Sbjct: 83 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDR----PL---SLTERHHLTPDN 135
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
LL +Q V EDAGR+ C ++NT+G+E H L V
Sbjct: 136 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 170
Score = 38.3 bits (85), Expect = 0.042
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEP---NERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
L+C GHP + W +G T P R+ ++ D I + DD G+Y C A N+
Sbjct: 8 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNS 67
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 67.7 bits (158), Expect = 6e-11
Identities = 48/162 (29%), Positives = 67/162 (41%), Gaps = 5/162 (3%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DEGLLSIQKVRRE 246
IR RL CA P P W + E +R ++ D+ + I V+ +
Sbjct: 610 IRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARE----RRMHVMPDDDVFFITDVKID 665
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
DAG + C N+ GS S + TL V E S+ E +AL CK G+P +
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRIT 725
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
W R L ER + D L ++N +D G Y C SN
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 767
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/186 (25%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPC-AVHAWPVP-TYRWFFEHHEQLTPIE-ETTLWKRAR 231
+KP++ + + VG+D+R C A + P T+ W + +E LT + E + A+
Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWK-KDNEVLTNADMENFVHVHAQ 551
Query: 232 ----LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK-PEVLRSK 286
+ +L +++V GR+ C + N GS H + + TK P + +
Sbjct: 552 DGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIR 611
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGRTLEP---NERIEILEDGLRLHIKNTHKDDQGIYQ 343
+ L+C GHP + W +G T P R+ ++ D I + DD G+Y
Sbjct: 612 TTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYS 671
Query: 344 CFASNA 349
C A N+
Sbjct: 672 CTAQNS 677
Score = 50.4 bits (115), Expect = 1e-05
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P + V R + VG+ V L C P P WF P+ +L +R L D
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDR----PL---SLTERHHLTPDN 745
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
LL +Q V EDAGR+ C ++NT+G+E H L V
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 67.7 bits (158), Expect = 6e-11
Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 12/183 (6%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
P+ + +S+ ++ Q V+ C V P P WF E +++ A
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA---GSH 470
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE---VLRSKPK---SD 290
L + K R D+G + C +N G S +TL V + P VL+ D
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL-RLHIKNTHKDDQGIYQCFASNA 349
L C V G P+ + WL NG+ ++ E G+ LHI++ +D G Y C A NA
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 350 RDQ 352
Q
Sbjct: 589 LGQ 591
Score = 56.0 bits (129), Expect = 2e-07
Identities = 63/246 (25%), Positives = 94/246 (38%), Gaps = 33/246 (13%)
Query: 126 DDGSLYISAVSTSDRHN-RFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQR 184
D GS Y+ + R + + C + + + V + V E V P S +
Sbjct: 466 DAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVME----VAPSFSSVLK 521
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
+ GQD L C+V PVP W PI+ A + + L IQ
Sbjct: 522 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ----PIQYARSTCEAGVAE---LHIQDAL 574
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVL---RSKPK------------- 288
ED G + C N +G S + V E S R +L SKP
Sbjct: 575 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
Query: 289 ---SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQ 343
S + + +V+G+P V WLHNG ++ +E + G + L I+ +D G Y
Sbjct: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYT 694
Query: 344 CFASNA 349
C A N+
Sbjct: 695 CEAWNS 700
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query: 187 RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRRE 246
++ G V + V P P W +E I+E+ + + + L IQ+V E
Sbjct: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNE----IQESEDFHFEQRGTQHSLWIQEVFPE 688
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKS-------DIALDCKVNG 299
D G + C N+ G L V EP T+P + SKP+S + + C + G
Sbjct: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEPHD-GTQPWFI-SKPRSVTASLGQSVLISCAIAG 746
Query: 300 HPIELVYWLHNGRTL-EPNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASN 348
P V+WL +G+ L + E+L ED L +K G Y+ N
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILE-DGLR-LHIKNTHKDDQGIYQCFASNARDQ 352
CK+ G P V WL L+P+ R+ + E +G++ L I ++DD G+Y C N +
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
Query: 353 AYGMSEYLFDG 363
A +E G
Sbjct: 242 ASMSAELSIQG 252
Score = 42.3 bits (95), Expect = 0.003
Identities = 40/152 (26%), Positives = 66/152 (43%), Gaps = 10/152 (6%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
SL+I V D + C + +RT + + V EP G +P + RS
Sbjct: 679 SLWIQEVFPEDT-GTYTCEAWNSAGEVRTQ-----AVLTVQEPHDGTQPWFISKPRSVTA 732
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
+GQ V + CA+ P PT W + ++T ++ + D L ++KV+ A
Sbjct: 733 SLGQSVLISCAIAGDPFPTVHWL---RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
Query: 249 GRFVCWLNNTVGSESVHFTLIVTEPISVRTKP 280
G++ L N VG S +L++ + S R P
Sbjct: 790 GQYEILLKNRVGECSCQVSLML-QNSSARALP 820
Score = 42.3 bits (95), Expect = 0.003
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASN 348
+ L C+V+ P + W NG+TL+ + I + ++G + I+ +D+G+Y+C A N
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKN 1174
Query: 349 ARDQA 353
QA
Sbjct: 1175 DAGQA 1179
Score = 36.3 bits (80), Expect = 0.17
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 270 VTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR- 328
+TE + P L K + + +V G+P V W NG+ + R +L+ G+R
Sbjct: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRG 87
Query: 329 ---LHIKNTHKDDQGIYQCFASN 348
L I H++D+G Y C A+N
Sbjct: 88 TFSLVIHAVHEEDRGKYTCEATN 110
Score = 36.3 bits (80), Expect = 0.17
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNE--RIEILEDG-LRLHIKNTHKDDQGIYQCFASNAR 350
DCK+ G+P V W + +++ + +I+ EDG L I + DD Y C A N+
Sbjct: 1777 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1836
Query: 351 DQAYGMSEYLFD 362
+A +E++ +
Sbjct: 1837 GEATCTAEHIVE 1848
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G P + + + G+ + L C V + P T W + + L + L + L
Sbjct: 1095 GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL-NGKTLKTTKFIILSQEGSLC 1153
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE-PISVRTK-PEVLRSKPKSDI 291
+SI+K ED G + C N G + V + P S TK PE+ +PKS +
Sbjct: 1154 S---VSIEKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 67.7 bits (158), Expect = 6e-11
Identities = 48/162 (29%), Positives = 67/162 (41%), Gaps = 5/162 (3%)
Query: 188 IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DEGLLSIQKVRRE 246
IR RL CA P P W + E +R ++ D+ + I V+ +
Sbjct: 610 IRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARE----RRMHVMPDDDVFFITDVKID 665
Query: 247 DAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
DAG + C N+ GS S + TL V E S+ E +AL CK G+P +
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRIT 725
Query: 307 WLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
W R L ER + D L ++N +D G Y C SN
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 767
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/186 (25%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPC-AVHAWPVP-TYRWFFEHHEQLTPIE-ETTLWKRAR 231
+KP++ + + VG+D+R C A + P T+ W + +E LT + E + A+
Sbjct: 493 LKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWK-KDNEVLTNADMENFVHVHAQ 551
Query: 232 ----LLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTK-PEVLRSK 286
+ +L +++V GR+ C + N GS H + + TK P + +
Sbjct: 552 DGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIR 611
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGRTLEP---NERIEILEDGLRLHIKNTHKDDQGIYQ 343
+ L+C GHP + W +G T P R+ ++ D I + DD G+Y
Sbjct: 612 TTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYS 671
Query: 344 CFASNA 349
C A N+
Sbjct: 672 CTAQNS 677
Score = 50.4 bits (115), Expect = 1e-05
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL-DE 235
P + V R + VG+ V L C P P WF P+ +L +R L D
Sbjct: 693 PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDR----PL---SLTERHHLTPDN 745
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV 270
LL +Q V EDAGR+ C ++NT+G+E H L V
Sbjct: 746 QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 67.7 bits (158), Expect = 6e-11
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 175 VKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
V PR+ + R++ IRV RL C P+PT RWF + Q + ++ +
Sbjct: 492 VPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWF--KNGQGSNLDGGNY----HV 544
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
+ G L I+ +R+ED G + C N +G L V +P + PE ++ + +
Sbjct: 545 YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQ 604
Query: 293 LDCKVNGHP-IEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
L+C+V P ++L V WL + L R++ +D L I + DQG Y C AS
Sbjct: 605 LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLT--IFGVAERDQGSYTCVASTEL 662
Query: 351 DQ 352
DQ
Sbjct: 663 DQ 664
Score = 65.7 bits (153), Expect = 2e-10
Identities = 76/328 (23%), Positives = 121/328 (36%), Gaps = 38/328 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C R+ G A+S I + + S W D V+ G + L+C PP +
Sbjct: 163 YQCFARNKFG-TALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF 221
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
W++ + + + +G LY S V D + C R T N
Sbjct: 222 --WMSSSMEPITQ--DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 277
Query: 164 SHVIVTEPKG--------------GVKPRVSV------EQRSRRIRVGQDVRLPCAVHAW 203
V+ P GV R S+ + G D+ L C
Sbjct: 278 LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 337
Query: 204 PVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES 263
P P W+ + + + + + +A L I V ED+G + C +N +GS
Sbjct: 338 PTPDIAWYKKGGDLPSDKAKFENFNKA-------LRITNVSEEDSGEYFCLASNKMGSIR 390
Query: 264 VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE---PNERI 320
++ V +P+ L P D L C+ NG+P V W+ NG L+ PN
Sbjct: 391 HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 450
Query: 321 EILEDGLRLHIKNTHKDDQGIYQCFASN 348
E+ D + ++T + +YQC SN
Sbjct: 451 EVAGD--TIIFRDTQISSRAVYQCNTSN 476
Score = 50.0 bits (114), Expect = 1e-05
Identities = 53/228 (23%), Positives = 91/228 (39%), Gaps = 20/228 (8%)
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRI 188
+L I+ VS D + C +K+ IR H I K P E ++ +
Sbjct: 364 ALRITNVSEEDS-GEYFCLASNKMGSIR--------HTISVRVKAA--PYWLDEPKNLIL 412
Query: 189 RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDA 248
G+D RL C + P PT +W P++ + + ++ + +
Sbjct: 413 APGEDGRLVCRANGNPKPTVQWMVNGE----PLQSAPPNPNREVAGDTII-FRDTQISSR 467
Query: 249 GRFVCWLNNTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVY 306
+ C +N G + +++ P + + +++R + LDC G PI +
Sbjct: 468 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 527
Query: 307 WLHNGRTLE-PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W NG+ + E+G L IK K+DQGIY C A+N +A
Sbjct: 528 WFKNGQGSNLDGGNYHVYENG-SLEIKMIRKEDQGIYTCVATNILGKA 574
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGR--TLEPNERIEILEDGLRLHIK----NTHKDDQG 340
P+ +I ++C+ G+P +W N R + + R+ + L I ++ +G
Sbjct: 102 PRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEG 161
Query: 341 IYQCFASN 348
YQCFA N
Sbjct: 162 EYQCFARN 169
>AL163283-1|CAB90464.1| 169|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 169
Score = 67.3 bits (157), Expect = 8e-11
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W + + + G+R + NG+L+I PF + +H Y C + G I S+++
Sbjct: 58 WYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIR-SQDV 116
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLND 109
H+ A L P+ V V D+ + GN V +C++P I+ W D
Sbjct: 117 HIKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKD 163
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 66.9 bits (156), Expect = 1e-10
Identities = 63/241 (26%), Positives = 101/241 (41%), Gaps = 22/241 (9%)
Query: 118 LGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKP 177
+GS H +GSL+I +V+ D +LC R+K+ + ++ HV + +KP
Sbjct: 16 VGSWIHVYPNGSLFIGSVTEKDS-GVYLCVARNKMGD-----DLILMHVSLR-----LKP 64
Query: 178 -RVSVEQRSRR-IRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT----LWKRAR 231
++ +Q R+ + G+D ++ C PVP W + + +R
Sbjct: 65 AKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYT 124
Query: 232 LLDEGLLSIQKVRREDAGRFVCWLNNTVGSES--VHFTLIVTEPISVRTKPEVLRSKPKS 289
L + G L KV + G + C+ NT+G + VH T+I P ++ R K
Sbjct: 125 LFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGD 184
Query: 290 DIALDCKVNGHPIELVYWL--HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
LDC+V G P ++WL N +R +G L I D G Y C A
Sbjct: 185 TAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG-SLTINKVKLLDSGEYVCVAR 243
Query: 348 N 348
N
Sbjct: 244 N 244
Score = 53.2 bits (122), Expect = 1e-06
Identities = 74/313 (23%), Positives = 129/313 (41%), Gaps = 23/313 (7%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C ++++G M ++ V A + + ++ + AG+ VL C V D
Sbjct: 144 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEV---TGDPKPKI 200
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
WL + +++ + +Y +GSL I+ V D ++C R+ +G T + L
Sbjct: 201 FWLLPSN-DMISFSIDRYTFHANGSLTINKVKLLD-SGEYVCVARNP-SGDDTKMYKL-- 255
Query: 165 HVIVTEPK--GGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
+V++P G+ +V ++ +R + C P P W + LT
Sbjct: 256 -DVVSKPPLINGLYTNRTV-IKATAVRHSKK-HFDCRAEGTPSPEVMWIMPDNIFLT--- 309
Query: 223 ETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT--KP 280
R + G L I+ VR D+ F+C N G + L V E + T P
Sbjct: 310 APYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNP 369
Query: 281 --EVLRSKPKSDIALDCKVNGH-PIELVYWLHNGRTLE--PNERIEILEDGLRLHIKNTH 335
E + ++ AL+C V+G+ P E+++ L NG P ++ I T
Sbjct: 370 FNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTT 429
Query: 336 KDDQGIYQCFASN 348
++D G Y+C A N
Sbjct: 430 REDAGKYRCAARN 442
Score = 52.8 bits (121), Expect = 2e-06
Identities = 81/366 (22%), Positives = 137/366 (37%), Gaps = 37/366 (10%)
Query: 3 WLQSDNTPV-ASLSGLR-QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK 60
W+ DN + A G R + KNG+LEI + + C R+ G +
Sbjct: 300 WIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLS------DSADFICVARNEGGESVLVV 353
Query: 61 NIHVYAALSSPWEVHVPDEYVIA--GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ V L P + +E ++A G + L C V + I W+ + +
Sbjct: 354 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEII---WILPNGTRFSNGP 410
Query: 119 GSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSH--VIVTEPKGGVK 176
S + + +I + +T + ++ C R+K+ I V + VI+T G VK
Sbjct: 411 QSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVK 470
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
+S G+ + L C P P +W ++ + + L D G
Sbjct: 471 G-IS----------GESLSLHCVSDGIPKPNIKWTMPSGYV---VDRPQINGKYILHDNG 516
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHF-TLIVTEPISVRTKP-EVLRSKPKSDIALD 294
L I++ D G ++C N+VG + +IV P + +P + ++ + L
Sbjct: 517 TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLH 576
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH------IKNTHKDDQGIYQCFASN 348
C G P + W +L E +LH I+N D GIY+C A N
Sbjct: 577 CVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKN 636
Query: 349 ARDQAY 354
Y
Sbjct: 637 PLGSDY 642
Score = 50.4 bits (115), Expect = 1e-05
Identities = 57/240 (23%), Positives = 102/240 (42%), Gaps = 29/240 (12%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+Y ++G+LY + V ++ + + C ++ + V+ V +T PR+
Sbjct: 122 RYTLFNNGTLYFNKVGVAEEGD-YTCYAQNTLGKDEMKVHLTV----IT-----AAPRIR 171
Query: 181 VEQRS-RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLL 238
++ +RI+ G L C V P P W ++ ++ I+ T G L
Sbjct: 172 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN------GSL 225
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVR---TKPEVLRSKP--KSDIA 292
+I KV+ D+G +VC N G ++ + L +V++P + T V+++ S
Sbjct: 226 TINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKH 285
Query: 293 LDCKVNGHPIELVYWL--HNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
DC+ G P V W+ N P RI + ++G L I+N D + C A N
Sbjct: 286 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG-TLEIRNVRLSDSADFICVARN 344
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 66.5 bits (155), Expect = 1e-10
Identities = 84/334 (25%), Positives = 127/334 (38%), Gaps = 22/334 (6%)
Query: 20 ILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE 79
+L NGSL I F E Y C ++ G + +S+ + AA S + VH
Sbjct: 90 LLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRKARIQAATMSDFHVHPQAT 148
Query: 80 YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSD 139
G +C + H + T N I+ + +Y L G L I+ + D
Sbjct: 149 VGEEGGVARFQCQI--HGLPKPLITWEKNRVPIDTDN---ERYTLLPKGVLQITGLRAED 203
Query: 140 RHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPC 198
F C V I IR + ++ + G K P + V + + V Q L C
Sbjct: 204 G-GIFHC-VASNIASIRISHGARLT--VSGSGSGAYKEPAILVGPENLTLTVHQTAVLEC 259
Query: 199 AVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN- 257
P P W PI + ++L G L I V + +G +VC N
Sbjct: 260 VATGNPRPIVSW---SRLDGRPIGVEGI----QVLGTGNLIISDVTVQHSGVYVCAANRP 312
Query: 258 -TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL-DCKVNGHPIELVYWLHNGRTLE 315
T + L+V P P+ + S+P A+ C+ G P V WL NG+ L
Sbjct: 313 GTRVRRTAQGRLVVQAPAEFVQHPQSI-SRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG 371
Query: 316 PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
P + + + L I +D+ IYQC A N+
Sbjct: 372 PGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENS 405
Score = 35.9 bits (79), Expect = 0.23
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRL--HIK---NTHKDDQGI 341
P I LDC+V G P + W NG L + +L +G + H + D+G
Sbjct: 55 PGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGD 114
Query: 342 YQCFASN 348
Y+C A N
Sbjct: 115 YECVAQN 121
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 66.5 bits (155), Expect = 1e-10
Identities = 84/334 (25%), Positives = 127/334 (38%), Gaps = 22/334 (6%)
Query: 20 ILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE 79
+L NGSL I F E Y C ++ G + +S+ + AA S + VH
Sbjct: 90 LLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRKARIQAATMSDFHVHPQAT 148
Query: 80 YVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSD 139
G +C + H + T N I+ + +Y L G L I+ + D
Sbjct: 149 VGEEGGVARFQCQI--HGLPKPLITWEKNRVPIDTDN---ERYTLLPKGVLQITGLRAED 203
Query: 140 RHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPC 198
F C V I IR + ++ + G K P + V + + V Q L C
Sbjct: 204 G-GIFHC-VASNIASIRISHGARLT--VSGSGSGAYKEPAILVGPENLTLTVHQTAVLEC 259
Query: 199 AVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN- 257
P P W PI + ++L G L I V + +G +VC N
Sbjct: 260 VATGNPRPIVSW---SRLDGRPIGVEGI----QVLGTGNLIISDVTVQHSGVYVCAANRP 312
Query: 258 -TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIAL-DCKVNGHPIELVYWLHNGRTLE 315
T + L+V P P+ + S+P A+ C+ G P V WL NG+ L
Sbjct: 313 GTRVRRTAQGRLVVQAPAEFVQHPQSI-SRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLG 371
Query: 316 PNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
P + + + L I +D+ IYQC A N+
Sbjct: 372 PGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENS 405
Score = 35.9 bits (79), Expect = 0.23
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 287 PKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRL--HIK---NTHKDDQGI 341
P I LDC+V G P + W NG L + +L +G + H + D+G
Sbjct: 55 PGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGD 114
Query: 342 YQCFASN 348
Y+C A N
Sbjct: 115 YECVAQN 121
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 66.5 bits (155), Expect = 1e-10
Identities = 50/161 (31%), Positives = 70/161 (43%), Gaps = 14/161 (8%)
Query: 192 QDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL-LDEGLLSIQKVRREDAGR 250
++V C + P PTY+W LT R R+ +++G L+I V DAG
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGEPLLT---------RDRIQIEQGTLNITIVNLSDAGM 53
Query: 251 FVCWLNNTVG--SESVHFTLIVTEPISVRT-KPEVLRSKPKSDIALDCKVNGHPIELVYW 307
+ C N G + ++I P RT V K ++ ++CK P + W
Sbjct: 54 YQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW 113
Query: 308 LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
L+ NERI I EDG L I N K D G Y C A+N
Sbjct: 114 KKGRDILKENERITISEDG-NLRIINVTKSDAGSYTCIATN 153
Score = 58.0 bits (134), Expect = 5e-08
Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 14/188 (7%)
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
+R ++VG +V + C A P P Y W + ++E +R + ++G L I
Sbjct: 86 KRVTLVKVGGEVVIECKPKASPKPVYTW----KKGRDILKEN---ERITISEDGNLRIIN 138
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGHP 301
V + DAG + C N G+ S L+V +P V P + I L C+V + H
Sbjct: 139 VTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHS 198
Query: 302 IELVY-WLHNGRTLE---PNERIEIL--EDGLRLHIKNTHKDDQGIYQCFASNARDQAYG 355
+++V+ W NG ++ + E + + L I+N G Y C + D+
Sbjct: 199 LDIVFTWSFNGHLIDFDRDGDHFERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSA 258
Query: 356 MSEYLFDG 363
++ + G
Sbjct: 259 AADLIVRG 266
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Query: 288 KSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
+ ++ +CK NG P WL NG L +RI+I + L + I N D G+YQC A
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNL--SDAGMYQCLAE 59
Query: 348 NARDQAYGMSE 358
N + +E
Sbjct: 60 NKHGVIFSNAE 70
Score = 38.7 bits (86), Expect = 0.032
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 16/151 (10%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
+DG+L I V+ SD + + C + TA +T +++V +P RV V S
Sbjct: 130 EDGNLRIINVTKSDAGS-YTCIATNHFG---TASST--GNLVVKDPT-----RVMVPPSS 178
Query: 186 RRIRVGQDVRLPCAV---HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
+ VG+ + LPC V H+ + + W F H + + ++R G L I+
Sbjct: 179 MDVTVGESIVLPCQVTHDHSLDI-VFTWSFNGH-LIDFDRDGDHFERVGGDSAGDLMIRN 236
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
++ + AG++VC + +V S LIV P
Sbjct: 237 IQLKHAGKYVCMVQTSVDRLSAAADLIVRGP 267
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 66.1 bits (154), Expect = 2e-10
Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 3086 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 3137
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 3138 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHAVLQISSAKPSDA-GTYVCLAQNALGTA 3194
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P PT W
Sbjct: 3195 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW----- 3245
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 3246 ---SKLRSPLPWQHR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3300
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 3301 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 3356
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 3357 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 3384
Score = 55.2 bits (127), Expect = 3e-07
Identities = 77/315 (24%), Positives = 113/315 (35%), Gaps = 36/315 (11%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAA--LSSPW-EVHVPDEYVIAGNAVVLRCVVPPHCA 98
A Y C + + +HV A+ LS+P +H P V G RC
Sbjct: 1835 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT---G 1891
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ EW L +K ++ G L + AV +D+ ++LCR G + A
Sbjct: 1892 SPTPTLEWTGGPG----GQLPAKA-QIHGGILRLPAVEPTDQA-QYLCRAHSS-AGQQVA 1944
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
L H GG PRV V ++ G+ VRL C P T W E L
Sbjct: 1945 RAVLHVH-------GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE-GGSL 1996
Query: 219 TPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIV-----TEP 273
P R+ D L I + DAG ++C + G+ ++V P
Sbjct: 1997 PP------QARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARMQVVVLSASDASP 2050
Query: 274 ISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKN 333
V+ + + L+C V G V W G +L P+ ++ G RL +
Sbjct: 2051 PGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVH----GSRLRLPQ 2106
Query: 334 THKDDQGIYQCFASN 348
D G Y C N
Sbjct: 2107 VSPADSGEYVCRVEN 2121
Score = 52.0 bits (119), Expect = 3e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 3276 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 3330
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 3331 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 3382
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 3383 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKEGG-QLP 3441
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 3442 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 3492
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 3493 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 3548
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 3549 DAGQYRCTATNA 3560
Score = 49.2 bits (112), Expect = 2e-05
Identities = 59/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
HRL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 3256 HRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 3304
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 3305 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 3354
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 3355 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 3414
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 3415 ASVEFHCAVPSDQGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 3468
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 3538 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 3596
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 3597 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQDAGTYVCTATN 3645
Score = 46.8 bits (106), Expect = 1e-04
Identities = 78/293 (26%), Positives = 115/293 (39%), Gaps = 44/293 (15%)
Query: 73 EVHVPDEYVIAGNAVVLRCVV---PPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
EVH V G + LRC V PPH W +D V G++ R
Sbjct: 1680 EVHPARSIVPQGGSHSLRCQVSGSPPHYF------YWSREDGRPVPS--GTQ-QRHQGSE 1730
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKGGVKPRVSVEQRSRRI 188
L+ +V SD ++C R+ NT + ++VTE P + V EQRS+ +
Sbjct: 1731 LHFPSVQPSDA-GVYICTCRNLHQS-----NTSRAELLVTEAPSKPITVTVE-EQRSQSV 1783
Query: 189 RVGQDVRLPCAVHAW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EGLLSIQKVRRE 246
R G DV C + P T W H+ +L R +D G+L+I+ V+
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLP----------TRAMDFNGILTIRNVQLS 1833
Query: 247 DAGRFVCWLNNTV----GSESVHFTL--IVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
DAG +VC +N G+ ++H ++ P+ V P L +P C G
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPV-VSIHPPQLTVQPGQLAEFRCSATGS 1892
Query: 301 PIELVYWLHN-GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
P + W G L +I G L + DQ Y C A ++ Q
Sbjct: 1893 PTPTLEWTGGPGGQLPAKAQIH----GGILRLPAVEPTDQAQYLCRAHSSAGQ 1941
Score = 44.0 bits (99), Expect = 9e-04
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 273 PISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--L 329
P V T P E +++ + C G P ++ W N + + R+ + +G R L
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 330 HIKNTHKDDQGIYQCFASNARDQAYGMSE 358
I++ + DQG Y C A NAR +G+ +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMVFGIPD 493
Score = 43.6 bits (98), Expect = 0.001
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 27/233 (11%)
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGVKPRVSVEQR 184
L + VS +D ++CRV + ++ V H + P G +P + +E
Sbjct: 2102 LRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP-IRIEPS 2159
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
S + GQ + L C V + H Q+T + LL + +V
Sbjct: 2160 SSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 2209
Query: 245 REDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKSDIALDCKVN 298
D+G +VC + T G SV T+ ++ PI VR + + L C V
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 2269
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
G V W G +L ++ G RL+I D G Y C ASN +
Sbjct: 2270 GQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNGME 2318
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 2332 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 2389
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 2390 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 2440
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 2491
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 2492 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 2550
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 2551 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 2604
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 2815 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 2862
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 2863 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 2921
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 2922 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 2978
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC + G E FT+ V +E S R + V+ P S
Sbjct: 2979 -------HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 3088
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 3089 YRCVASNA 3096
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 2481 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 2539
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 2540 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 2589
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPK----SDIAL 293
V D+G +VC ++N GS + + + SV + S P + L
Sbjct: 2590 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDL 2649
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 2650 NCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 2703
Score = 39.1 bits (87), Expect = 0.024
Identities = 75/316 (23%), Positives = 111/316 (35%), Gaps = 44/316 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y CR SS G +HV+ +V V AG V L C A S+T
Sbjct: 1931 YLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC----RAAGVPSAT 1986
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ ++ S+ R D +L I A++T+D +LC V G A
Sbjct: 1987 ITWRKEGGSLPPQARSE--RTDIATLLIPAITTADA-GFYLC-VATSPAGTAQAR----M 2038
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
V+V P V +E S + GQ + L C V W+ L P +
Sbjct: 2039 QVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWY-RRGGSLPPHTQ- 2096
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---------PIS 275
+ L + +V D+G +VC + N G + T+ V P+
Sbjct: 2097 --------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2148
Query: 276 VRTKPEVLRSKPKSD-------IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR 328
T+P +R +P S + L+C V G V W G +L + G
Sbjct: 2149 GSTRP--IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH----GSL 2202
Query: 329 LHIKNTHKDDQGIYQC 344
L + D G Y C
Sbjct: 2203 LRLHQVTPADSGEYVC 2218
Score = 37.9 bits (84), Expect = 0.056
Identities = 66/295 (22%), Positives = 105/295 (35%), Gaps = 40/295 (13%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDG 128
S P + +V G + L CVVP +++ W H H+
Sbjct: 2726 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---WHKRGGSLPSH------HQTRGS 2776
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVEQRS 185
L + VS +D ++CRV + +V + V P G P + +E S
Sbjct: 2777 RLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 2835
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
R+ GQ + L C V + H Q+T + + LL + +V
Sbjct: 2836 SRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSP 2885
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSDIAL 293
D+G + C + + G+ L+ EP S P ++P + L
Sbjct: 2886 ADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+C V G V W G +L R + LRLH+ D G Y C A++
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLP--ARHQTHGSQLRLHL--VSPADSGEYVCRAAS 2995
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 3560 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 3614
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + VR +DAG +VC N G L V E +
Sbjct: 3615 LPPDSR---------LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERV 3662
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 292 ALDCKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+L C+V+G P YW +GR + + G LH + D G+Y C N
Sbjct: 1695 SLRCQVSGSPPHYFYWSREDGRPVPSGTQQR--HQGSELHFPSVQPSDAGVYICTCRNLH 1752
Query: 351 DQAYGMSEYL 360
+E L
Sbjct: 1753 QSNTSRAELL 1762
Score = 33.1 bits (72), Expect = 1.6
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 26/232 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L I V+ +D ++C V + T++ + + V P + +E
Sbjct: 2578 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRIE 2635
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + GQ + L C V P W+ P T RL +
Sbjct: 2636 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------HQ 2685
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA------ 292
+ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 2686 MSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 2745
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + + G RL + + D G Y C
Sbjct: 2746 LNCVVPGQAHAQVTWHKRGGSLPSHHQTR----GSRLRLHHVSPADSGEYVC 2793
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/370 (24%), Positives = 151/370 (40%), Gaps = 42/370 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W ++D P+A + R+ NG LEI F E A +Y C +S G +
Sbjct: 259 WRRADGKPIARKA--RRHKSNGILEIPNFQQE------DAGLYECVAENSRGKNVARGQL 310
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST-EWLNDDDINVLHYLGSK 121
YA + W + D +V V C R T +WL + + L
Sbjct: 311 TFYAQPN--WIQKINDIHVAMEENVFWEC----KANGRPKPTYKWLKNGE----PLLTRD 360
Query: 122 YHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSV 181
+++ G+L I+ V+ SD + C +K I + N +S + V G ++
Sbjct: 361 RIQIEQGTLNITIVNLSDA-GMYQCLAENKHGVIFS--NAELSVIAV-----GPDFSRTL 412
Query: 182 EQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
+R ++VG +V + C A P P Y W + ++E +R + ++G L I
Sbjct: 413 LKRVTLVKVGGEVVIECKPKASPKPVYTW----KKGRDILKEN---ERITISEDGNLRII 465
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGH 300
V + DAG + C N G+ S L+V +P V P + I L C+V + H
Sbjct: 466 NVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDH 525
Query: 301 PIELVY-WLHNGRTLEPN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+++V+ W NG ++ + ER+ + L I+N G Y C + D+
Sbjct: 526 SLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRL 585
Query: 354 YGMSEYLFDG 363
++ + G
Sbjct: 586 SAAADLIVRG 595
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 23/188 (12%)
Query: 188 IRVGQDVRLPCAV--HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+R GQ + L C H+ + +Y W F + P + +R + G L I KV +
Sbjct: 134 VRRGQGMVLLCGPPPHSGEL-SYAWIFNEY----PSYQDN--RRFVSQETGNLYIAKVEK 186
Query: 246 EDAGRFVCWLNNTVGSESV---HFTLIVT--------EPISVRTKPEVLRSKPKSDIALD 294
D G + C + NTV + V LI+ EP PE + + + + L+
Sbjct: 187 SDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLE 246
Query: 295 CKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G+P+ + W +G+ + R +G+ L I N ++D G+Y+C A N+R +
Sbjct: 247 CFALGNPVPTIIWRRADGKPIARKAR-RHKSNGI-LEIPNFQQEDAGLYECVAENSRGKN 304
Query: 354 YGMSEYLF 361
+ F
Sbjct: 305 VARGQLTF 312
Score = 37.9 bits (84), Expect = 0.056
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 17/152 (11%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
+DG+L I V+ SD + + C + TA +T +++V +P RV V S
Sbjct: 458 EDGNLRIINVTKSDAGS-YTCIATNHFG---TASST--GNLVVKDPT-----RVMVPPSS 506
Query: 186 RRIRVGQDVRLPCAV---HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQ 241
+ VG+ + LPC V H+ + + W F H + + ++R D G L I+
Sbjct: 507 MDVTVGESIVLPCQVTHDHSLDI-VFTWSFNGH-LIDFDRDGDHFERVGGQDSAGDLMIR 564
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
++ + AG++VC + +V S LIV P
Sbjct: 565 NIQLKHAGKYVCMVQTSVDRLSAAADLIVRGP 596
Score = 37.5 bits (83), Expect = 0.074
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 263 SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP--NERI 320
++H + + EP V L S+ K + L+C+V G+P + W NG ++ + R
Sbjct: 22 TLHGPIFIQEPSPVMFP---LDSEEKK-VKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRY 77
Query: 321 EILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++E L ++ N D G YQC A+N+
Sbjct: 78 SVVEGSLLINNPN-KTQDAGTYQCTATNS 105
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 66.1 bits (154), Expect = 2e-10
Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 3086 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 3137
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 3138 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHAVLQISSAKPSDA-GTYVCLAQNALGTA 3194
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P PT W
Sbjct: 3195 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW----- 3245
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 3246 ---SKLRSPLPWQHR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3300
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 3301 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 3356
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 3357 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 3384
Score = 58.0 bits (134), Expect = 5e-08
Identities = 78/315 (24%), Positives = 113/315 (35%), Gaps = 36/315 (11%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAA--LSSPW-EVHVPDEYVIAGNAVVLRCVVPPHCA 98
A Y C + + +HV A+ LS+P +H P V G RC
Sbjct: 1835 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT---G 1891
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ EW L +K ++ G L + AV +D+ ++LCR G + A
Sbjct: 1892 SPTPTLEWTGGPG----GQLPAKA-QIHGGILRLPAVEPTDQA-QYLCRAHSS-AGQQVA 1944
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
L H GG PRV V ++ G+ VRL C P T W E L
Sbjct: 1945 RAVLHVH-------GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE-GGSL 1996
Query: 219 TPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P R+ D L I + DAG ++C + G+ ++V
Sbjct: 1997 PP------QARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASP 2050
Query: 279 KPEVLRSKPKS-----DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKN 333
P + S S + L+C V G V W G +L P+ ++ G RL +
Sbjct: 2051 PPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVH----GSRLRLPQ 2106
Query: 334 THKDDQGIYQCFASN 348
D G Y C N
Sbjct: 2107 VSPADSGEYVCRVEN 2121
Score = 51.6 bits (118), Expect = 4e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 3276 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 3330
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 3331 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 3382
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 3383 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGG-QLP 3441
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 3442 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 3492
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 3493 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 3548
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 3549 DAGQYRCTATNA 3560
Score = 48.8 bits (111), Expect = 3e-05
Identities = 59/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
HRL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 3256 HRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 3304
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 3305 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 3354
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 3355 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 3414
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 3415 ASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 3468
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 3538 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 3596
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 3597 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQDAGTYVCTATN 3645
Score = 46.8 bits (106), Expect = 1e-04
Identities = 78/293 (26%), Positives = 115/293 (39%), Gaps = 44/293 (15%)
Query: 73 EVHVPDEYVIAGNAVVLRCVV---PPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
EVH V G + LRC V PPH W +D V G++ R
Sbjct: 1680 EVHPARSIVPQGGSHSLRCQVSGSPPHYF------YWSREDGRPVPS--GTQ-QRHQGSE 1730
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKGGVKPRVSVEQRSRRI 188
L+ +V SD ++C R+ NT + ++VTE P + V EQRS+ +
Sbjct: 1731 LHFPSVQPSDA-GVYICTCRNLHQS-----NTSRAELLVTEAPSKPITVTVE-EQRSQSV 1783
Query: 189 RVGQDVRLPCAVHAW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EGLLSIQKVRRE 246
R G DV C + P T W H+ +L R +D G+L+I+ V+
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLP----------TRAMDFNGILTIRNVQLS 1833
Query: 247 DAGRFVCWLNNTV----GSESVHFTL--IVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
DAG +VC +N G+ ++H ++ P+ V P L +P C G
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPV-VSIHPPQLTVQPGQLAEFRCSATGS 1892
Query: 301 PIELVYWLHN-GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
P + W G L +I G L + DQ Y C A ++ Q
Sbjct: 1893 PTPTLEWTGGPGGQLPAKAQIH----GGILRLPAVEPTDQAQYLCRAHSSAGQ 1941
Score = 44.0 bits (99), Expect = 9e-04
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 273 PISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--L 329
P V T P E +++ + C G P ++ W N + + R+ + +G R L
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 330 HIKNTHKDDQGIYQCFASNARDQAYGMSE 358
I++ + DQG Y C A NAR +G+ +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMVFGIPD 493
Score = 43.6 bits (98), Expect = 0.001
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 27/233 (11%)
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGVKPRVSVEQR 184
L + VS +D ++CRV + ++ V H + P G +P + +E
Sbjct: 2102 LRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP-IRIEPS 2159
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
S + GQ + L C V + H Q+T + LL + +V
Sbjct: 2160 SSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 2209
Query: 245 REDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKSDIALDCKVN 298
D+G +VC + T G SV T+ ++ PI VR + + L C V
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 2269
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
G V W G +L ++ G RL+I D G Y C ASN +
Sbjct: 2270 GQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNGME 2318
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 2332 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 2389
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 2390 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 2440
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 2491
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 2492 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 2550
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 2551 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 2604
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 2815 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 2862
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 2863 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 2921
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 2922 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 2978
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC + G E FT+ V +E S R + V+ P S
Sbjct: 2979 -------HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 3088
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 3089 YRCVASNA 3096
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 2481 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 2539
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 2540 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 2589
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPK----SDIAL 293
V D+G +VC ++N GS + + + SV + S P + L
Sbjct: 2590 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDL 2649
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 2650 NCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 2703
Score = 39.1 bits (87), Expect = 0.024
Identities = 76/316 (24%), Positives = 113/316 (35%), Gaps = 44/316 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y CR SS G +HV+ +V V AG V L C A S+T
Sbjct: 1931 YLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC----RAAGVPSAT 1986
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ ++ S+ R D +L I A++T+D +LC V G TA +
Sbjct: 1987 ITWRKEGGSLPPQARSE--RTDIATLLIPAITTADA-GFYLC-VATSPAG--TAQARI-- 2038
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
V+V P V +E S + GQ + L C V W+ L P +
Sbjct: 2039 QVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWY-RRGGSLPPHTQ- 2096
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---------PIS 275
+ L + +V D+G +VC + N G + T+ V P+
Sbjct: 2097 --------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2148
Query: 276 VRTKPEVLRSKPKSD-------IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR 328
T+P +R +P S + L+C V G V W G +L + G
Sbjct: 2149 GSTRP--IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH----GSL 2202
Query: 329 LHIKNTHKDDQGIYQC 344
L + D G Y C
Sbjct: 2203 LRLHQVTPADSGEYVC 2218
Score = 37.9 bits (84), Expect = 0.056
Identities = 66/295 (22%), Positives = 105/295 (35%), Gaps = 40/295 (13%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDG 128
S P + +V G + L CVVP +++ W H H+
Sbjct: 2726 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---WHKRGGSLPSH------HQTRGS 2776
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVEQRS 185
L + VS +D ++CRV + +V + V P G P + +E S
Sbjct: 2777 RLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 2835
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
R+ GQ + L C V + H Q+T + + LL + +V
Sbjct: 2836 SRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSP 2885
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSDIAL 293
D+G + C + + G+ L+ EP S P ++P + L
Sbjct: 2886 ADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+C V G V W G +L R + LRLH+ D G Y C A++
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLP--ARHQTHGSQLRLHL--VSPADSGEYVCRAAS 2995
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 3560 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 3614
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + VR +DAG +VC N G L V E +
Sbjct: 3615 LPPDSR---------LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERV 3662
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 292 ALDCKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+L C+V+G P YW +GR + + G LH + D G+Y C N
Sbjct: 1695 SLRCQVSGSPPHYFYWSREDGRPVPSGTQQR--HQGSELHFPSVQPSDAGVYICTCRNLH 1752
Query: 351 DQAYGMSEYL 360
+E L
Sbjct: 1753 QSNTSRAELL 1762
Score = 33.1 bits (72), Expect = 1.6
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 26/232 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L I V+ +D ++C V + T++ + + V P + +E
Sbjct: 2578 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRIE 2635
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + GQ + L C V P W+ P T RL +
Sbjct: 2636 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------HQ 2685
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA------ 292
+ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 2686 MSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 2745
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + + G RL + + D G Y C
Sbjct: 2746 LNCVVPGQAHAQVTWHKRGGSLPSHHQTR----GSRLRLHHVSPADSGEYVC 2793
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 66.1 bits (154), Expect = 2e-10
Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 3086 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 3137
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 3138 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHAVLQISSAKPSDA-GTYVCLAQNALGTA 3194
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P PT W
Sbjct: 3195 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW----- 3245
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 3246 ---SKLRSPLPWQHR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3300
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 3301 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 3356
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 3357 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 3384
Score = 58.0 bits (134), Expect = 5e-08
Identities = 78/315 (24%), Positives = 113/315 (35%), Gaps = 36/315 (11%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAA--LSSPW-EVHVPDEYVIAGNAVVLRCVVPPHCA 98
A Y C + + +HV A+ LS+P +H P V G RC
Sbjct: 1835 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT---G 1891
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ EW L +K ++ G L + AV +D+ ++LCR G + A
Sbjct: 1892 SPTPTLEWTGGPG----GQLPAKA-QIHGGILRLPAVEPTDQA-QYLCRAHSS-AGQQVA 1944
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
L H GG PRV V ++ G+ VRL C P T W E L
Sbjct: 1945 RAVLHVH-------GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE-GGSL 1996
Query: 219 TPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P R+ D L I + DAG ++C + G+ ++V
Sbjct: 1997 PP------QARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASP 2050
Query: 279 KPEVLRSKPKS-----DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKN 333
P + S S + L+C V G V W G +L P+ ++ G RL +
Sbjct: 2051 PPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVH----GSRLRLPQ 2106
Query: 334 THKDDQGIYQCFASN 348
D G Y C N
Sbjct: 2107 VSPADSGEYVCRVEN 2121
Score = 51.6 bits (118), Expect = 4e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 3276 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 3330
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 3331 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 3382
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 3383 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGG-QLP 3441
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 3442 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 3492
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 3493 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 3548
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 3549 DAGQYRCTATNA 3560
Score = 48.8 bits (111), Expect = 3e-05
Identities = 59/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
HRL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 3256 HRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 3304
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 3305 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 3354
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 3355 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 3414
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 3415 ASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 3468
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 3538 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 3596
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 3597 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQDAGTYVCTATN 3645
Score = 46.8 bits (106), Expect = 1e-04
Identities = 78/293 (26%), Positives = 115/293 (39%), Gaps = 44/293 (15%)
Query: 73 EVHVPDEYVIAGNAVVLRCVV---PPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
EVH V G + LRC V PPH W +D V G++ R
Sbjct: 1680 EVHPARSIVPQGGSHSLRCQVSGSPPHYF------YWSREDGRPVPS--GTQ-QRHQGSE 1730
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKGGVKPRVSVEQRSRRI 188
L+ +V SD ++C R+ NT + ++VTE P + V EQRS+ +
Sbjct: 1731 LHFPSVQPSDA-GVYICTCRNLHQS-----NTSRAELLVTEAPSKPITVTVE-EQRSQSV 1783
Query: 189 RVGQDVRLPCAVHAW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EGLLSIQKVRRE 246
R G DV C + P T W H+ +L R +D G+L+I+ V+
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLP----------TRAMDFNGILTIRNVQLS 1833
Query: 247 DAGRFVCWLNNTV----GSESVHFTL--IVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
DAG +VC +N G+ ++H ++ P+ V P L +P C G
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPV-VSIHPPQLTVQPGQLAEFRCSATGS 1892
Query: 301 PIELVYWLHN-GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
P + W G L +I G L + DQ Y C A ++ Q
Sbjct: 1893 PTPTLEWTGGPGGQLPAKAQIH----GGILRLPAVEPTDQAQYLCRAHSSAGQ 1941
Score = 44.0 bits (99), Expect = 9e-04
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 273 PISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--L 329
P V T P E +++ + C G P ++ W N + + R+ + +G R L
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 330 HIKNTHKDDQGIYQCFASNARDQAYGMSE 358
I++ + DQG Y C A NAR +G+ +
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGMVFGIPD 493
Score = 43.6 bits (98), Expect = 0.001
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 27/233 (11%)
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGVKPRVSVEQR 184
L + VS +D ++CRV + ++ V H + P G +P + +E
Sbjct: 2102 LRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP-IRIEPS 2159
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
S + GQ + L C V + H Q+T + LL + +V
Sbjct: 2160 SSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 2209
Query: 245 REDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKSDIALDCKVN 298
D+G +VC + T G SV T+ ++ PI VR + + L C V
Sbjct: 2210 PADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 2269
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
G V W G +L ++ G RL+I D G Y C ASN +
Sbjct: 2270 GQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNGME 2318
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 2332 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 2389
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 2390 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 2440
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 2441 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 2491
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 2492 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 2550
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 2551 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 2604
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 2815 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 2862
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 2863 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 2921
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 2922 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 2978
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC + G E FT+ V +E S R + V+ P S
Sbjct: 2979 -------HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 3088
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 3089 YRCVASNA 3096
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 2481 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 2539
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 2540 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 2589
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPK----SDIAL 293
V D+G +VC ++N GS + + + SV + S P + L
Sbjct: 2590 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDL 2649
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 2650 NCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 2703
Score = 39.1 bits (87), Expect = 0.024
Identities = 76/316 (24%), Positives = 113/316 (35%), Gaps = 44/316 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y CR SS G +HV+ +V V AG V L C A S+T
Sbjct: 1931 YLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC----RAAGVPSAT 1986
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ ++ S+ R D +L I A++T+D +LC V G TA +
Sbjct: 1987 ITWRKEGGSLPPQARSE--RTDIATLLIPAITTADA-GFYLC-VATSPAG--TAQARI-- 2038
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
V+V P V +E S + GQ + L C V W+ L P +
Sbjct: 2039 QVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWY-RRGGSLPPHTQ- 2096
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---------PIS 275
+ L + +V D+G +VC + N G + T+ V P+
Sbjct: 2097 --------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2148
Query: 276 VRTKPEVLRSKPKSD-------IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR 328
T+P +R +P S + L+C V G V W G +L + G
Sbjct: 2149 GSTRP--IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH----GSL 2202
Query: 329 LHIKNTHKDDQGIYQC 344
L + D G Y C
Sbjct: 2203 LRLHQVTPADSGEYVC 2218
Score = 37.9 bits (84), Expect = 0.056
Identities = 66/295 (22%), Positives = 105/295 (35%), Gaps = 40/295 (13%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDG 128
S P + +V G + L CVVP +++ W H H+
Sbjct: 2726 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---WHKRGGSLPSH------HQTRGS 2776
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVEQRS 185
L + VS +D ++CRV + +V + V P G P + +E S
Sbjct: 2777 RLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 2835
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
R+ GQ + L C V + H Q+T + + LL + +V
Sbjct: 2836 SRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSP 2885
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSDIAL 293
D+G + C + + G+ L+ EP S P ++P + L
Sbjct: 2886 ADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2944
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+C V G V W G +L R + LRLH+ D G Y C A++
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLP--ARHQTHGSQLRLHL--VSPADSGEYVCRAAS 2995
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 3560 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 3614
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + VR +DAG +VC N G L V E +
Sbjct: 3615 LPPDSR---------LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERV 3662
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 292 ALDCKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+L C+V+G P YW +GR + + G LH + D G+Y C N
Sbjct: 1695 SLRCQVSGSPPHYFYWSREDGRPVPSGTQQR--HQGSELHFPSVQPSDAGVYICTCRNLH 1752
Query: 351 DQAYGMSEYL 360
+E L
Sbjct: 1753 QSNTSRAELL 1762
Score = 33.1 bits (72), Expect = 1.6
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 26/232 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L I V+ +D ++C V + T++ + + V P + +E
Sbjct: 2578 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRIE 2635
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + GQ + L C V P W+ P T RL +
Sbjct: 2636 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------HQ 2685
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA------ 292
+ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 2686 MSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 2745
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + + G RL + + D G Y C
Sbjct: 2746 LNCVVPGQAHAQVTWHKRGGSLPSHHQTR----GSRLRLHHVSPADSGEYVC 2793
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 66.1 bits (154), Expect = 2e-10
Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 3065 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 3116
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 3117 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHAVLQISSAKPSDA-GTYVCLAQNALGTA 3173
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P PT W
Sbjct: 3174 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW----- 3224
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 3225 ---SKLRSPLPWQHR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3279
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 3280 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 3335
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 3336 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 3363
Score = 58.0 bits (134), Expect = 5e-08
Identities = 78/315 (24%), Positives = 113/315 (35%), Gaps = 36/315 (11%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAA--LSSPW-EVHVPDEYVIAGNAVVLRCVVPPHCA 98
A Y C + + +HV A+ LS+P +H P V G RC
Sbjct: 1814 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT---G 1870
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ EW L +K ++ G L + AV +D+ ++LCR G + A
Sbjct: 1871 SPTPTLEWTGGPG----GQLPAKA-QIHGGILRLPAVEPTDQA-QYLCRAHSS-AGQQVA 1923
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
L H GG PRV V ++ G+ VRL C P T W E L
Sbjct: 1924 RAVLHVH-------GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE-GGSL 1975
Query: 219 TPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P R+ D L I + DAG ++C + G+ ++V
Sbjct: 1976 PP------QARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASP 2029
Query: 279 KPEVLRSKPKS-----DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKN 333
P + S S + L+C V G V W G +L P+ ++ G RL +
Sbjct: 2030 PPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVH----GSRLRLPQ 2085
Query: 334 THKDDQGIYQCFASN 348
D G Y C N
Sbjct: 2086 VSPADSGEYVCRVEN 2100
Score = 51.6 bits (118), Expect = 4e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 3255 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 3309
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 3310 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 3361
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 3362 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGG-QLP 3420
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 3421 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 3471
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 3472 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 3527
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 3528 DAGQYRCTATNA 3539
Score = 48.8 bits (111), Expect = 3e-05
Identities = 59/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
HRL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 3235 HRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 3283
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 3284 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 3333
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 3334 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 3393
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 3394 ASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 3447
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 3517 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 3575
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 3576 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQDAGTYVCTATN 3624
Score = 46.8 bits (106), Expect = 1e-04
Identities = 78/293 (26%), Positives = 115/293 (39%), Gaps = 44/293 (15%)
Query: 73 EVHVPDEYVIAGNAVVLRCVV---PPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGS 129
EVH V G + LRC V PPH W +D V G++ R
Sbjct: 1659 EVHPARSIVPQGGSHSLRCQVSGSPPHYF------YWSREDGRPVPS--GTQ-QRHQGSE 1709
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKGGVKPRVSVEQRSRRI 188
L+ +V SD ++C R+ NT + ++VTE P + V EQRS+ +
Sbjct: 1710 LHFPSVQPSDA-GVYICTCRNLHQS-----NTSRAELLVTEAPSKPITVTVE-EQRSQSV 1762
Query: 189 RVGQDVRLPCAVHAW-PVPTYRWFFEHHEQLTPIEETTLWKRARLLD-EGLLSIQKVRRE 246
R G DV C + P T W H+ +L R +D G+L+I+ V+
Sbjct: 1763 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLP----------TRAMDFNGILTIRNVQLS 1812
Query: 247 DAGRFVCWLNNTV----GSESVHFTL--IVTEPISVRTKPEVLRSKPKSDIALDCKVNGH 300
DAG +VC +N G+ ++H ++ P+ V P L +P C G
Sbjct: 1813 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPV-VSIHPPQLTVQPGQLAEFRCSATGS 1871
Query: 301 PIELVYWLHN-GRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQ 352
P + W G L +I G L + DQ Y C A ++ Q
Sbjct: 1872 PTPTLEWTGGPGGQLPAKAQIH----GGILRLPAVEPTDQAQYLCRAHSSAGQ 1920
Score = 44.0 bits (99), Expect = 9e-04
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 273 PISVRTKP-EVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--L 329
P V T P E +++ + C G P ++ W N + + R+ + +G R L
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 443
Query: 330 HIKNTHKDDQGIYQCFASNARDQAYGMSE 358
I++ + DQG Y C A NAR +G+ +
Sbjct: 444 IIRDVKESDQGAYTCEAMNARGMVFGIPD 472
Score = 43.6 bits (98), Expect = 0.001
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 27/233 (11%)
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGVKPRVSVEQR 184
L + VS +D ++CRV + ++ V H + P G +P + +E
Sbjct: 2081 LRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP-IRIEPS 2138
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
S + GQ + L C V + H Q+T + LL + +V
Sbjct: 2139 SSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 2188
Query: 245 REDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKSDIALDCKVN 298
D+G +VC + T G SV T+ ++ PI VR + + L C V
Sbjct: 2189 PADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 2248
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
G V W G +L ++ G RL+I D G Y C ASN +
Sbjct: 2249 GQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNGME 2297
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 2311 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 2368
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 2369 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 2419
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 2420 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 2470
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 2471 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 2529
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 2530 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 2583
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 2794 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 2841
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 2842 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 2900
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 2901 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 2957
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC + G E FT+ V +E S R + V+ P S
Sbjct: 2958 -------HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3010
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 3011 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 3067
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 3068 YRCVASNA 3075
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 2460 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 2518
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 2519 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 2568
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPK----SDIAL 293
V D+G +VC ++N GS + + + SV + S P + L
Sbjct: 2569 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDL 2628
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 2629 NCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 2682
Score = 39.1 bits (87), Expect = 0.024
Identities = 76/316 (24%), Positives = 113/316 (35%), Gaps = 44/316 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y CR SS G +HV+ +V V AG V L C A S+T
Sbjct: 1910 YLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC----RAAGVPSAT 1965
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
+ ++ S+ R D +L I A++T+D +LC V G TA +
Sbjct: 1966 ITWRKEGGSLPPQARSE--RTDIATLLIPAITTADA-GFYLC-VATSPAG--TAQARI-- 2017
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
V+V P V +E S + GQ + L C V W+ L P +
Sbjct: 2018 QVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWY-RRGGSLPPHTQ- 2075
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE---------PIS 275
+ L + +V D+G +VC + N G + T+ V P+
Sbjct: 2076 --------VHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2127
Query: 276 VRTKPEVLRSKPKSD-------IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR 328
T+P +R +P S + L+C V G V W G +L + G
Sbjct: 2128 GSTRP--IRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTH----GSL 2181
Query: 329 LHIKNTHKDDQGIYQC 344
L + D G Y C
Sbjct: 2182 LRLHQVTPADSGEYVC 2197
Score = 37.9 bits (84), Expect = 0.056
Identities = 66/295 (22%), Positives = 105/295 (35%), Gaps = 40/295 (13%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDG 128
S P + +V G + L CVVP +++ W H H+
Sbjct: 2705 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---WHKRGGSLPSH------HQTRGS 2755
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVEQRS 185
L + VS +D ++CRV + +V + V P G P + +E S
Sbjct: 2756 RLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 2814
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
R+ GQ + L C V + H Q+T + + LL + +V
Sbjct: 2815 SRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSP 2864
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSDIAL 293
D+G + C + + G+ L+ EP S P ++P + L
Sbjct: 2865 ADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 2923
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+C V G V W G +L R + LRLH+ D G Y C A++
Sbjct: 2924 NCVVPGQAHAQVTWYKRGGSLP--ARHQTHGSQLRLHL--VSPADSGEYVCRAAS 2974
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 3539 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 3593
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + VR +DAG +VC N G L V E +
Sbjct: 3594 LPPDSR---------LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERV 3641
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 292 ALDCKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+L C+V+G P YW +GR + + G LH + D G+Y C N
Sbjct: 1674 SLRCQVSGSPPHYFYWSREDGRPVPSGTQQR--HQGSELHFPSVQPSDAGVYICTCRNLH 1731
Query: 351 DQAYGMSEYL 360
+E L
Sbjct: 1732 QSNTSRAELL 1741
Score = 33.1 bits (72), Expect = 1.6
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 26/232 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L I V+ +D ++C V + T++ + + V P + +E
Sbjct: 2557 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRIE 2614
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + GQ + L C V P W+ P T RL +
Sbjct: 2615 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------HQ 2664
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA------ 292
+ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 2665 MSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 2724
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + + G RL + + D G Y C
Sbjct: 2725 LNCVVPGQAHAQVTWHKRGGSLPSHHQTR----GSRLRLHHVSPADSGEYVC 2772
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 66.1 bits (154), Expect = 2e-10
Identities = 56/199 (28%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 156 RTAVNTLVSHVIVT-EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEH 214
R + HV +T + VKP SV R ++V LPC P PT W E
Sbjct: 61 RNSAGVAHKHVFLTVQASPVVKPLPSVV----RAVAEEEVLLPCEASGIPRPTITWQKEG 116
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
T + ++L G L I EDAG ++C N+ GS L+V P
Sbjct: 117 LNVATGVS-------TQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPP 169
Query: 275 SVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNT 334
+ L + S L CK G P + W +G+ + E ++ L +KN
Sbjct: 170 VIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNL 229
Query: 335 HKDDQGIYQCFASNARDQA 353
D G Y C A NA +A
Sbjct: 230 EGQDAGTYTCTAENAVGRA 248
Score = 61.3 bits (142), Expect = 5e-09
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Query: 231 RLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSD 290
R+ G L I + AGR+ C N+ G H L V V+ P V+R+ + +
Sbjct: 36 RVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEE 95
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNAR 350
+ L C+ +G P + W G + ++L G +L I + +D G Y C A N+
Sbjct: 96 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG-QLRIAHASPEDAGNYLCIAKNSA 154
Query: 351 DQAYG 355
A G
Sbjct: 155 GSAMG 159
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 66.1 bits (154), Expect = 2e-10
Identities = 89/370 (24%), Positives = 151/370 (40%), Gaps = 42/370 (11%)
Query: 3 WLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNI 62
W ++D P+A + R+ NG LEI F E A +Y C +S G +
Sbjct: 259 WRRADGKPIARKA--RRHKSNGILEIPNFQQE------DAGLYECVAENSRGKNVARGQL 310
Query: 63 HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST-EWLNDDDINVLHYLGSK 121
YA + W + D +V V C R T +WL + + L
Sbjct: 311 TFYAQPN--WIQKINDIHVAMEENVFWEC----KANGRPKPTYKWLKNGE----PLLTRD 360
Query: 122 YHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSV 181
+++ G+L I+ V+ SD + C +K I + N +S + V G ++
Sbjct: 361 RIQIEQGTLNITIVNLSDA-GMYQCLAENKHGVIFS--NAELSVIAV-----GPDFSRTL 412
Query: 182 EQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
+R ++VG +V + C A P P Y W + ++E +R + ++G L I
Sbjct: 413 LKRVTLVKVGGEVVIECKPKASPKPVYTW----KKGRDILKEN---ERITISEDGNLRII 465
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV-NGH 300
V + DAG + C N G+ S L+V +P V P + I L C+V + H
Sbjct: 466 NVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDH 525
Query: 301 PIELVY-WLHNGRTLEPN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
+++V+ W NG ++ + ER+ + L I+N G Y C + D+
Sbjct: 526 SLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRL 585
Query: 354 YGMSEYLFDG 363
++ + G
Sbjct: 586 SAAADLIVRG 595
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 23/188 (12%)
Query: 188 IRVGQDVRLPCAV--HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+R GQ + L C H+ + +Y W F + P + +R + G L I KV +
Sbjct: 134 VRRGQGMVLLCGPPPHSGEL-SYAWIFNEY----PSYQDN--RRFVSQETGNLYIAKVEK 186
Query: 246 EDAGRFVCWLNNTVGSESV---HFTLIVT--------EPISVRTKPEVLRSKPKSDIALD 294
D G + C + NTV + V LI+ EP PE + + + + L+
Sbjct: 187 SDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLE 246
Query: 295 CKVNGHPIELVYWLH-NGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G+P+ + W +G+ + R +G+ L I N ++D G+Y+C A N+R +
Sbjct: 247 CFALGNPVPTIIWRRADGKPIARKAR-RHKSNGI-LEIPNFQQEDAGLYECVAENSRGKN 304
Query: 354 YGMSEYLF 361
+ F
Sbjct: 305 VARGQLTF 312
Score = 37.9 bits (84), Expect = 0.056
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 17/152 (11%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
+DG+L I V+ SD + + C + TA +T +++V +P RV V S
Sbjct: 458 EDGNLRIINVTKSDAGS-YTCIATNHFG---TASST--GNLVVKDPT-----RVMVPPSS 506
Query: 186 RRIRVGQDVRLPCAV---HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQ 241
+ VG+ + LPC V H+ + + W F H + + ++R D G L I+
Sbjct: 507 MDVTVGESIVLPCQVTHDHSLDI-VFTWSFNGH-LIDFDRDGDHFERVGGQDSAGDLMIR 564
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
++ + AG++VC + +V S LIV P
Sbjct: 565 NIQLKHAGKYVCMVQTSVDRLSAAADLIVRGP 596
Score = 37.5 bits (83), Expect = 0.074
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 263 SVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEP--NERI 320
++H + + EP V L S+ K + L+C+V G+P + W NG ++ + R
Sbjct: 22 TLHGPIFIQEPSPVMFP---LDSEEKK-VKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRY 77
Query: 321 EILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++E L ++ N D G YQC A+N+
Sbjct: 78 SVVEGSLLINNPN-KTQDAGTYQCTATNS 105
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 58.4 bits (135), Expect = 4e-08
Identities = 45/198 (22%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE--------VLRSK 286
G L I V++EDAG++ C N++G+ ++ +V + ++PE +LR+
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTA---YSKVVKLEVEEESEPEQDTKVFARILRAP 228
Query: 287 PK------SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQG 340
S + L C G P+ + W+ NG + E ++D + G
Sbjct: 229 ESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPG 288
Query: 341 IYQCFASNARDQAYGMSE 358
+Y C A+N + + ++
Sbjct: 289 LYTCIATNKHGEKFSTAK 306
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 65.7 bits (153), Expect = 2e-10
Identities = 63/242 (26%), Positives = 103/242 (42%), Gaps = 22/242 (9%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+Y D SL+I VS D + C V + G A +L HV P++
Sbjct: 302 RYEIRSDHSLWIGHVSAEDE-GTYTC-VAENSVGRAEASGSLSVHV---------PPQLV 350
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLS 239
+ + + G+ V C P P W E + L P + R + G L+
Sbjct: 351 TQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLN 410
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK-------SDIA 292
I V+R DAG +VC + GS + L+ + S+ P V+ P S +
Sbjct: 411 ITAVQRGDAGYYVCQAVSVAGS-ILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVW 469
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L C+V G+P V W +G+ L+ ++ + + + +G L+I N + D G Y C A ++
Sbjct: 470 LPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG-TLYIANVQEMDMGFYSCVAKSSTG 528
Query: 352 QA 353
+A
Sbjct: 529 EA 530
Score = 62.9 bits (146), Expect = 2e-09
Identities = 86/338 (25%), Positives = 129/338 (38%), Gaps = 35/338 (10%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVP 77
R +L +G+L P R VY C R+ +G A S+N + A+ P
Sbjct: 115 RLLLPSGAL-FFPRIVHGRRARPDEGVYTCVARNYLG-AAASRNASLEVAVLRDDFRQSP 172
Query: 78 DEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
V+A G VL CV P + S W D + G R G L +S
Sbjct: 173 GNVVVAVGEPAVLECVPPRGHPE--PSVSW-RKDGARLKEEEGRITIR--GGKLMMSHTL 227
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
SD ++C V + G R + + V+V E +P ++ + V
Sbjct: 228 KSDA-GMYVC-VASNMAGERESA---AAEVMVLE-----RPSFLRRPVNQVVLADAPVTF 277
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C V P P RW E E T R + + L I V ED G + C
Sbjct: 278 LCEVKGDPPPRLRWRKEDGELPTG--------RYEIRSDHSLWIGHVSAEDEGTYTCVAE 329
Query: 257 NTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG----- 311
N+VG +L V P + T+P+ + P +A C+ G+P ++W G
Sbjct: 330 NSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLL 389
Query: 312 ---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
++L+P R + G +L+I + D G Y C A
Sbjct: 390 FPSQSLQPTGRFSVSPRG-QLNITAVQRGDAGYYVCQA 426
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 13/181 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ LPC P P W+ ++ ++ + E R LL G
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWY-KNGARVATVREDPRAHRL-LLPSG 121
Query: 237 LLSIQKV-----RREDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKS 289
L ++ R D G + C N +G+ + + + R P +
Sbjct: 122 ALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGE 181
Query: 290 DIALDC-KVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
L+C GHP V W +G L+ E RI I G +L + +T K D G+Y C AS
Sbjct: 182 PAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIR--GGKLMMSHTLKSDAGMYVCVAS 239
Query: 348 N 348
N
Sbjct: 240 N 240
Score = 30.7 bits (66), Expect = 8.5
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 6/114 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ P + ++ + +G V LPC V P P+ RW + Q ++ + + +
Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRW--KKDGQWLQGDDL----QFKTM 501
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP 287
G L I V+ D G + C ++ G + L + E V P S P
Sbjct: 502 ANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSP 555
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/160 (31%), Positives = 71/160 (44%), Gaps = 11/160 (6%)
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLN 256
CAV ++P P W ++ L + +T R + + G LL+I V D G + C N
Sbjct: 49 CAVESYPQPEISW--TRNKILIKLFDT----RYSIRENGQLLTILSVEDSDDGIYCCTAN 102
Query: 257 NTVGS--ESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTL 314
N VG ES + +P + P ++ L C G+P V W+ L
Sbjct: 103 NGVGGAVESCGALQVKMKP-KITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPL 161
Query: 315 EPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAY 354
N RI +LE G L I N K+D G Y+C A N+ AY
Sbjct: 162 RENSRIAVLESG-SLRIHNVQKEDAGQYRCVAKNSLGTAY 200
Score = 63.7 bits (148), Expect = 1e-09
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 8/185 (4%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLD 234
+KP+++ + +I G LPC P P+ W + +P+ E + R +L+
Sbjct: 119 MKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWI----KGDSPLRENS---RIAVLE 171
Query: 235 EGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-VRTKPEVLRSKPKSDIAL 293
G L I V++EDAG++ C N++G+ + E + + PE S + L
Sbjct: 172 SGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTL 231
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
C G P+ + W+ NG + E ++D + G+Y C A+N +
Sbjct: 232 HCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEK 291
Query: 354 YGMSE 358
+ ++
Sbjct: 292 FSTAK 296
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 65.3 bits (152), Expect = 3e-10
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 9/167 (5%)
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+ + G+D + C V + P P W + H+E++T I + R +L L I + +
Sbjct: 124 QEFKQGEDAEVVCRVSSSPAPAVSWLY-HNEEVTTISDN----RLAMLANNNLQILNINK 178
Query: 246 EDAGRFVCW----LNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
D G + C + + + V IS+ K ++ ++ C+ +G P
Sbjct: 179 SDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSP 238
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NG+ +E NE+ + L ++N D G Y C A+N
Sbjct: 239 EPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATN 285
Score = 55.6 bits (128), Expect = 3e-07
Identities = 86/372 (23%), Positives = 146/372 (39%), Gaps = 39/372 (10%)
Query: 1 MDWLQSDNTPVASLSGLRQILKNGSLEILPFTAELYRHDVH-ATVYRCRMRSSVGYIAMS 59
+DW + S R +++ G + +Y ++ A +YRC+ + G +
Sbjct: 51 IDWYNPQGEKIISTQ--RVVVQKGGVRS---RLTIYNANIEDAGIYRCQATDAKGQTQEA 105
Query: 60 KNI-HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ +Y L+ EV P E+ +A V+ C V A +S WL ++ V
Sbjct: 106 TVVLEIYQKLTFR-EVVSPQEFKQGEDAEVV-CRVSSSPAPAVS---WLYHNE-EVTTIS 159
Query: 119 GSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPR 178
++ L + +L I ++ SD + C R + G ++ VIV P P+
Sbjct: 160 DNRLAMLANNNLQILNINKSDE-GIYRCEGRVEARG---EIDFRDIIVIVNVPPAISMPQ 215
Query: 179 VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLL 238
S + R G+++ C P P WF + +L E + K + L
Sbjct: 216 KSFNATAER---GEEMTFSCRASGSPEPAISWF--RNGKLIEENEKYILKGSNTE----L 266
Query: 239 SIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
+++ + D G +VC N G E F + +P ++ K E + + L C
Sbjct: 267 TVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNET--TYENGQVTLVCDA 324
Query: 298 NGHPIELVYWLH--NGRTL-----EPNERIEI--LEDGLRLHIKNTHKDDQGIYQCFASN 348
G PI + W +G T P+ RIE+ LHIK+ G Y C A+
Sbjct: 325 EGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAA- 383
Query: 349 ARDQAYGMSEYL 360
+R + S YL
Sbjct: 384 SRIGGHQKSMYL 395
Score = 35.9 bits (79), Expect = 0.23
Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
C G P + ++ G + +R+ + + G+R L I N + +D GIY+C A++A+ Q
Sbjct: 42 CTAIGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAKGQ 101
Score = 32.3 bits (70), Expect = 2.8
Identities = 25/115 (21%), Positives = 46/115 (40%), Gaps = 4/115 (3%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I+ V+ +GR+ C + +G L + + + S + I + C V
Sbjct: 365 LHIKDVKLSGSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDV 424
Query: 298 NGHPIELVYWLHNGRTL--EPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASN 348
+P ++W + L + ++ G + L I T +D G Y C A+N
Sbjct: 425 KSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 65.3 bits (152), Expect = 3e-10
Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 1026 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 1077
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 1078 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHAVLQISSAKPSDA-GTYVCLAQNALGTA 1134
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P PT W
Sbjct: 1135 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW----- 1185
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 1186 ---SKLRSPLPWQYR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 1240
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 1241 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 1296
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 1297 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 1324
Score = 51.6 bits (118), Expect = 4e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 1216 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 1270
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 1271 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 1322
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 1323 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGG-QLP 1381
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 1382 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 1432
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 1433 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 1488
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 1489 DAGQYRCTATNA 1500
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 1478 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 1536
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 1537 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVRPQDAGTYVCTATN 1585
Score = 46.4 bits (105), Expect = 2e-04
Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
+RL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 1196 YRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 1244
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 1245 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 1294
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 1295 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 1354
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 1355 ASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 1408
Score = 43.6 bits (98), Expect = 0.001
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 27/233 (11%)
Query: 130 LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGVKPRVSVEQR 184
L + VS +D ++CRV + ++ V H + P G +P + +E
Sbjct: 42 LRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRP-IRIEPS 99
Query: 185 SRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVR 244
S + GQ + L C V + H Q+T + LL + +V
Sbjct: 100 SSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 149
Query: 245 REDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKSDIALDCKVN 298
D+G +VC + T G SV T+ ++ PI VR + + L C V
Sbjct: 150 PADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVA 209
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
G V W G +L ++ G RL+I D G Y C ASN +
Sbjct: 210 GQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNGME 258
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 272 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 329
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 330 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 380
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 381 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 431
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 432 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 490
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 491 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 544
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 114/308 (37%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 755 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 802
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 803 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 861
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 862 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 918
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC + G E FT+ V +E S R + V+ P S
Sbjct: 919 -------HLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 971
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 972 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 1028
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 1029 YRCVASNA 1036
Score = 39.5 bits (88), Expect = 0.018
Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 421 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 479
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 480 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 529
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPK----SDIAL 293
V D+G +VC ++N GS + + + SV + S P + L
Sbjct: 530 VTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDL 589
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 590 NCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 643
Score = 37.9 bits (84), Expect = 0.056
Identities = 66/295 (22%), Positives = 105/295 (35%), Gaps = 40/295 (13%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDG 128
S P + +V G + L CVVP +++ W H H+
Sbjct: 666 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---WHKRGGSLPSH------HQTRGS 716
Query: 129 SLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVEQRS 185
L + VS +D ++CRV + +V + V P G P + +E S
Sbjct: 717 RLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 775
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
R+ GQ + L C V + H Q+T + + LL + +V
Sbjct: 776 SRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSP 825
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSDIAL 293
D+G + C + + G+ L+ EP S P ++P + L
Sbjct: 826 ADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDL 884
Query: 294 DCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+C V G V W G +L R + LRLH+ D G Y C A++
Sbjct: 885 NCVVPGQAHAQVTWYKRGGSLP--ARHQTHGSQLRLHL--VSPADSGEYVCRAAS 935
Score = 35.9 bits (79), Expect = 0.23
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 1500 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 1554
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + VR +DAG +VC N G L V E +
Sbjct: 1555 LPPDSR---------LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERV 1602
Score = 33.1 bits (72), Expect = 1.6
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 26/232 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L I V+ +D ++C V + T++ + + V P + +E
Sbjct: 518 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRIE 575
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + GQ + L C V P W+ P T RL +
Sbjct: 576 SSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------HQ 625
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA------ 292
+ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 626 MSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLD 685
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + + G RL + + D G Y C
Sbjct: 686 LNCVVPGQAHAQVTWHKRGGSLPSHHQTR----GSRLRLHHVSPADSGEYVC 733
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 64.9 bits (151), Expect = 4e-10
Identities = 78/320 (24%), Positives = 126/320 (39%), Gaps = 26/320 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A +Y C ++ G + ++ + L P+ V G +VL C P H D +
Sbjct: 109 AGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDL 168
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD-KITGIRTAVN 160
S WL ++ + ++ +G+LYI+ V SD+ N + C V IT ++ +
Sbjct: 169 SY-RWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN-YSCFVSSPSIT--KSVFS 224
Query: 161 TLVSHVIVTEPKGGVKPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ + + E P + V+ + +GQ+V L C PVP RW + L
Sbjct: 225 KFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW----RKVLE 280
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P+ T A + G +L I ++ ED G + C N G + + V
Sbjct: 281 PMPST-----AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVE 335
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDD 338
SD+ C G PI + WL NG E LRL+ + ++
Sbjct: 336 HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE--------LRLY--DVTFEN 385
Query: 339 QGIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 386 AGMYQCIAENTYGAIYANAE 405
Score = 54.0 bits (124), Expect = 8e-07
Identities = 73/354 (20%), Positives = 128/354 (36%), Gaps = 46/354 (12%)
Query: 26 LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIH--------VYAALSSPWEVHVP 77
LE +P TAE+ ++ ++ Y ++NI +Y W H+
Sbjct: 279 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 338
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
D V G+ + CV I + WL + G YH+ G L + V T
Sbjct: 339 DTEVDIGSDLYWPCVAT---GKPIPTIRWLKN---------GYAYHK---GELRLYDV-T 382
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+ + C + I + + T +K ++ + R I +
Sbjct: 383 FENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI-------IE 435
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C A P P + W + E L +W ++G L I + R D G + C+ N
Sbjct: 436 CKPKAAPKPKFSWS-KGTEWLVNSSRILIW------EDGSLEINNITRNDGGIYTCFAEN 488
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WLHNGRTLE 315
G + TL++T+P + P + + C + P ++L + W NG ++
Sbjct: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 316 PN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
N +R +L+ L I+N G Y C A D + ++ + G
Sbjct: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 14/162 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C A P P Y+W + + ++ T+ R ++ L+ +++DAG + C
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGD----VDLTS--DRYSMVGGNLVINNPDKQKDAGIYYC 114
Query: 254 WLNNTVGS-ESVHFTLI--VTEPISVRTKPEVLRSKPKSDIALDCKVNGH-PIELVY-WL 308
+N G S TL +P +PEV R K + L C H P +L Y WL
Sbjct: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEV-RVKEGKGMVLLCDPPYHFPDDLSYRWL 173
Query: 309 HNGRT--LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + ++R + + L+I N D+G Y CF S+
Sbjct: 174 LNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 44.4 bits (100), Expect = 6e-04
Identities = 62/251 (24%), Positives = 111/251 (44%), Gaps = 33/251 (13%)
Query: 34 ELYRHDV---HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA--GNAVV 88
EL +DV +A +Y+C ++ G I + + + A L+ +E++ + ++A G V+
Sbjct: 375 ELRLYDVTFENAGMYQCIAENTYGAIYANAELKILA-LAPTFEMNPMKKKILAAKGGRVI 433
Query: 89 LRC---VVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFL 145
+ C P TEWL +N S+ +DGSL I+ ++ +D +
Sbjct: 434 IECKPKAAPKPKFSWSKGTEWL----VN-----SSRILIWEDGSLEINNITRNDG-GIYT 483
Query: 146 CRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPV 205
C + G + TLV +T+P R+ + + I VG++ + CA P
Sbjct: 484 CFAENN-RGKANSTGTLV----ITDPT-----RIILAPINADITVGENATMQCAASFDPA 533
Query: 206 P--TYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSE 262
T+ W F + + +E ++R +LD G L I+ + + AGR+ C V +
Sbjct: 534 LDLTFVWSFNGYV-IDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNS 592
Query: 263 SVHFTLIVTEP 273
S L+V P
Sbjct: 593 SASADLVVRGP 603
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 64.9 bits (151), Expect = 4e-10
Identities = 78/320 (24%), Positives = 126/320 (39%), Gaps = 26/320 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A +Y C ++ G + ++ + L P+ V G +VL C P H D +
Sbjct: 98 AGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDL 157
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD-KITGIRTAVN 160
S WL ++ + ++ +G+LYI+ V SD+ N + C V IT ++ +
Sbjct: 158 SY-RWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN-YSCFVSSPSIT--KSVFS 213
Query: 161 TLVSHVIVTEPKGGVKPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ + + E P + V+ + +GQ+V L C PVP RW + L
Sbjct: 214 KFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW----RKVLE 269
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P+ T A + G +L I ++ ED G + C N G + + V
Sbjct: 270 PMPST-----AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVE 324
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDD 338
SD+ C G PI + WL NG E LRL+ + ++
Sbjct: 325 HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE--------LRLY--DVTFEN 374
Query: 339 QGIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 375 AGMYQCIAENTYGAIYANAE 394
Score = 54.0 bits (124), Expect = 8e-07
Identities = 73/354 (20%), Positives = 128/354 (36%), Gaps = 46/354 (12%)
Query: 26 LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIH--------VYAALSSPWEVHVP 77
LE +P TAE+ ++ ++ Y ++NI +Y W H+
Sbjct: 268 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 327
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
D V G+ + CV I + WL + G YH+ G L + V T
Sbjct: 328 DTEVDIGSDLYWPCVAT---GKPIPTIRWLKN---------GYAYHK---GELRLYDV-T 371
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+ + C + I + + T +K ++ + R I +
Sbjct: 372 FENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI-------IE 424
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C A P P + W + E L +W ++G L I + R D G + C+ N
Sbjct: 425 CKPKAAPKPKFSWS-KGTEWLVNSSRILIW------EDGSLEINNITRNDGGIYTCFAEN 477
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WLHNGRTLE 315
G + TL++T+P + P + + C + P ++L + W NG ++
Sbjct: 478 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 537
Query: 316 PN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
N +R +L+ L I+N G Y C A D + ++ + G
Sbjct: 538 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRG 591
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 14/162 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C A P P Y+W + + ++ T+ R ++ L+ +++DAG + C
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGD----VDLTS--DRYSMVGGNLVINNPDKQKDAGIYYC 103
Query: 254 WLNNTVGS-ESVHFTLI--VTEPISVRTKPEVLRSKPKSDIALDCKVNGH-PIELVY-WL 308
+N G S TL +P +PEV R K + L C H P +L Y WL
Sbjct: 104 LASNNYGMVRSTEATLSFGYLDPFPPEERPEV-RVKEGKGMVLLCDPPYHFPDDLSYRWL 162
Query: 309 HNGRT--LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + ++R + + L+I N D+G Y CF S+
Sbjct: 163 LNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
Score = 44.4 bits (100), Expect = 6e-04
Identities = 62/251 (24%), Positives = 111/251 (44%), Gaps = 33/251 (13%)
Query: 34 ELYRHDV---HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA--GNAVV 88
EL +DV +A +Y+C ++ G I + + + A L+ +E++ + ++A G V+
Sbjct: 364 ELRLYDVTFENAGMYQCIAENTYGAIYANAELKILA-LAPTFEMNPMKKKILAAKGGRVI 422
Query: 89 LRC---VVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFL 145
+ C P TEWL +N S+ +DGSL I+ ++ +D +
Sbjct: 423 IECKPKAAPKPKFSWSKGTEWL----VN-----SSRILIWEDGSLEINNITRNDG-GIYT 472
Query: 146 CRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPV 205
C + G + TLV +T+P R+ + + I VG++ + CA P
Sbjct: 473 CFAENN-RGKANSTGTLV----ITDPT-----RIILAPINADITVGENATMQCAASFDPA 522
Query: 206 P--TYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSE 262
T+ W F + + +E ++R +LD G L I+ + + AGR+ C V +
Sbjct: 523 LDLTFVWSFNGYV-IDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNS 581
Query: 263 SVHFTLIVTEP 273
S L+V P
Sbjct: 582 SASADLVVRGP 592
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 64.9 bits (151), Expect = 4e-10
Identities = 78/320 (24%), Positives = 126/320 (39%), Gaps = 26/320 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A +Y C ++ G + ++ + L P+ V G +VL C P H D +
Sbjct: 109 AGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDL 168
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD-KITGIRTAVN 160
S WL ++ + ++ +G+LYI+ V SD+ N + C V IT ++ +
Sbjct: 169 SY-RWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN-YSCFVSSPSIT--KSVFS 224
Query: 161 TLVSHVIVTEPKGGVKPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ + + E P + V+ + +GQ+V L C PVP RW + L
Sbjct: 225 KFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW----RKVLE 280
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P+ T A + G +L I ++ ED G + C N G + + V
Sbjct: 281 PMPST-----AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVE 335
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDD 338
SD+ C G PI + WL NG E LRL+ + ++
Sbjct: 336 HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE--------LRLY--DVTFEN 385
Query: 339 QGIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 386 AGMYQCIAENTYGAIYANAE 405
Score = 54.0 bits (124), Expect = 8e-07
Identities = 73/354 (20%), Positives = 128/354 (36%), Gaps = 46/354 (12%)
Query: 26 LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIH--------VYAALSSPWEVHVP 77
LE +P TAE+ ++ ++ Y ++NI +Y W H+
Sbjct: 279 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 338
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
D V G+ + CV I + WL + G YH+ G L + V T
Sbjct: 339 DTEVDIGSDLYWPCVAT---GKPIPTIRWLKN---------GYAYHK---GELRLYDV-T 382
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+ + C + I + + T +K ++ + R I +
Sbjct: 383 FENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI-------IE 435
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C A P P + W + E L +W ++G L I + R D G + C+ N
Sbjct: 436 CKPKAAPKPKFSWS-KGTEWLVNSSRILIW------EDGSLEINNITRNDGGIYTCFAEN 488
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WLHNGRTLE 315
G + TL++T+P + P + + C + P ++L + W NG ++
Sbjct: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 316 PN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
N +R +L+ L I+N G Y C A D + ++ + G
Sbjct: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 14/162 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C A P P Y+W + + ++ T+ R ++ L+ +++DAG + C
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGD----VDLTS--DRYSMVGGNLVINNPDKQKDAGIYYC 114
Query: 254 WLNNTVGS-ESVHFTLI--VTEPISVRTKPEVLRSKPKSDIALDCKVNGH-PIELVY-WL 308
+N G S TL +P +PEV R K + L C H P +L Y WL
Sbjct: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEV-RVKEGKGMVLLCDPPYHFPDDLSYRWL 173
Query: 309 HNGRT--LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + ++R + + L+I N D+G Y CF S+
Sbjct: 174 LNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 44.4 bits (100), Expect = 6e-04
Identities = 62/251 (24%), Positives = 111/251 (44%), Gaps = 33/251 (13%)
Query: 34 ELYRHDV---HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA--GNAVV 88
EL +DV +A +Y+C ++ G I + + + A L+ +E++ + ++A G V+
Sbjct: 375 ELRLYDVTFENAGMYQCIAENTYGAIYANAELKILA-LAPTFEMNPMKKKILAAKGGRVI 433
Query: 89 LRC---VVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFL 145
+ C P TEWL +N S+ +DGSL I+ ++ +D +
Sbjct: 434 IECKPKAAPKPKFSWSKGTEWL----VN-----SSRILIWEDGSLEINNITRNDG-GIYT 483
Query: 146 CRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPV 205
C + G + TLV +T+P R+ + + I VG++ + CA P
Sbjct: 484 CFAENN-RGKANSTGTLV----ITDPT-----RIILAPINADITVGENATMQCAASFDPA 533
Query: 206 P--TYRWFFEHHEQLTPIEETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSE 262
T+ W F + + +E ++R +LD G L I+ + + AGR+ C V +
Sbjct: 534 LDLTFVWSFNGYV-IDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNS 592
Query: 263 SVHFTLIVTEP 273
S L+V P
Sbjct: 593 SASADLVVRGP 603
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 64.9 bits (151), Expect = 4e-10
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 9/167 (5%)
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRR 245
+ + G+D + C V + P P W + H+E++T I + R +L L I + +
Sbjct: 124 QEFKQGEDAEVVCRVSSSPAPAVSWLY-HNEEVTTISDN----RFAMLANNNLQILNINK 178
Query: 246 EDAGRFVCW----LNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP 301
D G + C + + + V IS+ K ++ ++ C+ +G P
Sbjct: 179 SDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSP 238
Query: 302 IELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ W NG+ +E NE+ + L ++N D G Y C A+N
Sbjct: 239 EPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATN 285
Score = 57.2 bits (132), Expect = 9e-08
Identities = 80/330 (24%), Positives = 132/330 (40%), Gaps = 33/330 (10%)
Query: 42 ATVYRCRMRSSVGYIAMSKNI-HVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADR 100
A +YRC+ + G + + +Y L+ EV P E+ +A V+ C V A
Sbjct: 88 AGIYRCQATDAKGQTQEATVVLEIYQKLTFR-EVVSPQEFKQGEDAEVV-CRVSSSPAPA 145
Query: 101 ISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVN 160
+S WL ++ V +++ L + +L I ++ SD + C R + G ++
Sbjct: 146 VS---WLYHNE-EVTTISDNRFAMLANNNLQILNINKSDE-GIYRCEGRVEARG---EID 197
Query: 161 TLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTP 220
VIV P P+ S + R G+++ C P P WF + +L
Sbjct: 198 FRDIIVIVNVPPAISMPQKSFNATAER---GEEMTFSCRASGSPEPAISWF--RNGKLIE 252
Query: 221 IEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG-SESVHFTLIVTEPISVRTK 279
E + K + L+++ + D G +VC N G E F + +P ++ K
Sbjct: 253 ENEKYILKGSNTE----LTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLK 308
Query: 280 PEVLRSKPKSDIALDCKVNGHPIELVYWLH--NGRTLEPNE-----RIEI--LEDGLRLH 330
E + + L C G PI + W +G T + RIE+ LH
Sbjct: 309 NET--TYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLH 366
Query: 331 IKNTHKDDQGIYQCFASNARDQAYGMSEYL 360
IK+ D G Y C A+ +R + S YL
Sbjct: 367 IKDVKLSDSGRYDCEAA-SRIGGHQKSMYL 395
Score = 37.1 bits (82), Expect = 0.098
Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
C G P + ++ G + +R+ + ++G+R L I N + +D GIY+C A++A+ Q
Sbjct: 42 CTAIGEPESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQ 101
Score = 35.1 bits (77), Expect = 0.39
Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 4/115 (3%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L I+ V+ D+GR+ C + +G L + + + S + I + C V
Sbjct: 365 LHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDV 424
Query: 298 NGHPIELVYWLHNGRTL--EPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASN 348
+P ++W + L + ++ G + L I T +D G Y C A+N
Sbjct: 425 KSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 64.9 bits (151), Expect = 4e-10
Identities = 78/320 (24%), Positives = 126/320 (39%), Gaps = 26/320 (8%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRI 101
A +Y C ++ G + ++ + L P+ V G +VL C P H D +
Sbjct: 109 AGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDL 168
Query: 102 SSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD-KITGIRTAVN 160
S WL ++ + ++ +G+LYI+ V SD+ N + C V IT ++ +
Sbjct: 169 SY-RWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN-YSCFVSSPSIT--KSVFS 224
Query: 161 TLVSHVIVTEPKGGVKPR-VSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ + + E P + V+ + +GQ+V L C PVP RW + L
Sbjct: 225 KFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW----RKVLE 280
Query: 220 PIEETTLWKRARLLDEG-LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P+ T A + G +L I ++ ED G + C N G + + V
Sbjct: 281 PMPST-----AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVE 335
Query: 279 KPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDD 338
SD+ C G PI + WL NG E LRL+ + ++
Sbjct: 336 HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGE--------LRLY--DVTFEN 385
Query: 339 QGIYQCFASNARDQAYGMSE 358
G+YQC A N Y +E
Sbjct: 386 AGMYQCIAENTYGAIYANAE 405
Score = 54.0 bits (124), Expect = 8e-07
Identities = 73/354 (20%), Positives = 128/354 (36%), Gaps = 46/354 (12%)
Query: 26 LEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIH--------VYAALSSPWEVHVP 77
LE +P TAE+ ++ ++ Y ++NI +Y W H+
Sbjct: 279 LEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHIN 338
Query: 78 DEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVST 137
D V G+ + CV I + WL + G YH+ G L + V T
Sbjct: 339 DTEVDIGSDLYWPCVAT---GKPIPTIRWLKN---------GYAYHK---GELRLYDV-T 382
Query: 138 SDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
+ + C + I + + T +K ++ + R I +
Sbjct: 383 FENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI-------IE 435
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNN 257
C A P P + W + E L +W ++G L I + R D G + C+ N
Sbjct: 436 CKPKAAPKPKFSWS-KGTEWLVNSSRILIW------EDGSLEINNITRNDGGIYTCFAEN 488
Query: 258 TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WLHNGRTLE 315
G + TL++T+P + P + + C + P ++L + W NG ++
Sbjct: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
Query: 316 PN------ERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGMSEYLFDG 363
N +R +L+ L I+N G Y C A D + ++ + G
Sbjct: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/162 (27%), Positives = 71/162 (43%), Gaps = 14/162 (8%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVC 253
V L C A P P Y+W + + ++ T+ R ++ L+ +++DAG + C
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGD----VDLTS--DRYSMVGGNLVINNPDKQKDAGIYYC 114
Query: 254 WLNNTVGS-ESVHFTLI--VTEPISVRTKPEVLRSKPKSDIALDCKVNGH-PIELVY-WL 308
+N G S TL +P +PEV R K + L C H P +L Y WL
Sbjct: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEV-RVKEGKGMVLLCDPPYHFPDDLSYRWL 173
Query: 309 HNGRT--LEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
N + ++R + + L+I N D+G Y CF S+
Sbjct: 174 LNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 64.9 bits (151), Expect = 4e-10
Identities = 75/312 (24%), Positives = 136/312 (43%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 333 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 388
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 389 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 441
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT +WF +
Sbjct: 442 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIQWF-------KGAK 488
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + +P + +PE
Sbjct: 489 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPE 548
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 549 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 606
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 607 GTYTCVANTTLD 618
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 110 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 168
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 169 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 224
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 225 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 283
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 284 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 336
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 337 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 394
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 395 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 431
Score = 38.3 bits (85), Expect = 0.042
Identities = 56/237 (23%), Positives = 94/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 422 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 475
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + +W + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 476 SPLPTIQWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 532
Query: 159 VNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPCAV-HAWPVPTYRWFFEHHE 216
V H+ + +P VK P +V QR G V C V H + + + +
Sbjct: 533 V-----HLEIKDPTWIVKQPEYAVVQR------GSMVSFECKVKHDHTLSLTVLWLKDNR 581
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
+L E T+ D+ L + V +D+G + C N T+ S S L V P
Sbjct: 582 ELPSDERFTV-------DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 631
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 283 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 340
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 37 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 96
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 97 GTLIINIMSEGKAETYEGVYQCTARNERGAA 127
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 64.5 bits (150), Expect = 6e-10
Identities = 75/312 (24%), Positives = 135/312 (43%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 332 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 387
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 388 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 440
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 441 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 487
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + +P + +PE
Sbjct: 488 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPE 547
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 605
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 606 GTYTCVANTTLD 617
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 109 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 167
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 168 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 223
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 224 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 282
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 283 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 335
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 336 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 393
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 394 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 430
Score = 37.9 bits (84), Expect = 0.056
Identities = 56/236 (23%), Positives = 94/236 (39%), Gaps = 32/236 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 474
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 475 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 531
Query: 159 VNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPCAV-HAWPVPTYRWFFEHHE 216
V H+ + +P VK P +V QR G V C V H + + + +
Sbjct: 532 V-----HLEIKDPTWIVKQPEYAVVQR------GSMVSFECKVKHDHTLSLTVLWLKDNR 580
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
+L E T+ D+ L + V +D+G + C N T+ S S L V +
Sbjct: 581 ELPSDERFTV-------DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD 629
Score = 37.5 bits (83), Expect = 0.074
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 242 KVRREDAGR--FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
K +R AGR + +L + + V L V P + P+ P+ +I + C+ G
Sbjct: 8 KKKRLSAGRVPLILFLCQMISALEVPLDL-VQPPTITQQSPKDYIIDPRENIVIQCEAKG 66
Query: 300 HPIELVYWLHNGRTLE-PNERIEILEDG---LRLHIKNTHKDD--QGIYQCFASNARDQA 353
P W NG + + + ++ G L ++I + K + +G+YQC A N R A
Sbjct: 67 KPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA 126
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 282 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 339
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 64.5 bits (150), Expect = 6e-10
Identities = 62/242 (25%), Positives = 102/242 (42%), Gaps = 22/242 (9%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+Y D SL+I VS D + C V + G A +L HV P++
Sbjct: 302 RYEIRSDHSLWIGHVSAEDE-GTYTC-VAENSVGRAEASGSLSVHV---------PPQLV 350
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLS 239
+ + + G+ V C P P W E + L P + R + G L+
Sbjct: 351 TQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLN 410
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK-------SDIA 292
I V+R DAG ++C + GS L+ + S+ P V+ P S +
Sbjct: 411 ITAVQRGDAGYYMCQAVSVAGSILAK-ALLEIKGASLDGLPPVILQGPANQTLVLGSSVW 469
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L C+V G+P V W +G+ L+ ++ + + + +G L+I N + D G Y C A ++
Sbjct: 470 LPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANG-TLYIANVQEMDMGFYSCVAKSSTG 528
Query: 352 QA 353
+A
Sbjct: 529 EA 530
Score = 63.7 bits (148), Expect = 1e-09
Identities = 86/338 (25%), Positives = 129/338 (38%), Gaps = 35/338 (10%)
Query: 18 RQILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVP 77
R +L +G+L P R VY C R+ +G A S+N + A+ P
Sbjct: 115 RLLLPSGAL-FFPRIVHGRRARPDEGVYTCVARNYLG-AAASRNASLEVAVLRDDFRQSP 172
Query: 78 DEYVIA-GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVS 136
V+A G VL CV P + S W D + G R G L +S
Sbjct: 173 GNVVVAVGEPAVLECVPPRGHPE--PSVSW-RKDGARLKEEEGRITIR--GGKLMMSHTL 227
Query: 137 TSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRL 196
SD ++C V + G R + + V+V E +P ++ + V
Sbjct: 228 KSDA-GMYVC-VASNMAGERESA---AAEVMVLE-----RPSFLRRPVNQVVLADAPVTF 277
Query: 197 PCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLN 256
C V P P RW E E T R + + L I V ED G + C
Sbjct: 278 LCEVKGDPPPRLRWRKEDGELPTG--------RYEIRSDHSLWIGHVSAEDEGTYTCVAE 329
Query: 257 NTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNG----- 311
N+VG +L V P + T+P+ + P +A C+ G+P ++W G
Sbjct: 330 NSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLL 389
Query: 312 ---RTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
++L+P R + G +L+I + D G Y C A
Sbjct: 390 FPSQSLQPTGRFSVSPRG-QLNITAVQRGDAGYYMCQA 426
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/181 (25%), Positives = 73/181 (40%), Gaps = 13/181 (7%)
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
PR+ + + G+ LPC P P W+ ++ ++ + E R LL G
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWY-KNGARVATVREDPRAHRL-LLPSG 121
Query: 237 LLSIQKV-----RREDAGRFVCWLNNTVGSESVHFTLIVTEPI--SVRTKPEVLRSKPKS 289
L ++ R D G + C N +G+ + + + R P +
Sbjct: 122 ALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGE 181
Query: 290 DIALDC-KVNGHPIELVYWLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
L+C GHP V W +G L+ E RI I G +L + +T K D G+Y C AS
Sbjct: 182 PAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIR--GGKLMMSHTLKSDAGMYVCVAS 239
Query: 348 N 348
N
Sbjct: 240 N 240
Score = 30.7 bits (66), Expect = 8.5
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 6/114 (5%)
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ P + ++ + +G V LPC V P P+ RW + Q ++ + + +
Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRW--KKDGQWLQGDDL----QFKTM 501
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP 287
G L I V+ D G + C ++ G + L + E V P S P
Sbjct: 502 ANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSP 555
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 64.5 bits (150), Expect = 6e-10
Identities = 75/312 (24%), Positives = 135/312 (43%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 338 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 393
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 394 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 446
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 447 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 493
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + +P + +PE
Sbjct: 494 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPE 553
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 554 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 611
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 612 GTYTCVANTTLD 623
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 115 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 174 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 229
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 230 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 288
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 289 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 341
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 342 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 400 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 436
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/237 (24%), Positives = 94/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 427 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 480
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 481 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 537
Query: 159 VNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPCAV-HAWPVPTYRWFFEHHE 216
V H+ + +P VK P +V QR G V C V H + + + +
Sbjct: 538 V-----HLEIKDPTWIVKQPEYAVVQR------GSMVSFECKVKHDHTLSLTVLWLKDNR 586
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
+L E T+ D+ L + V +D+G + C N T+ S S L V P
Sbjct: 587 ELPSDERFTV-------DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 288 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 345
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAA 132
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 64.5 bits (150), Expect = 6e-10
Identities = 75/312 (24%), Positives = 135/312 (43%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 338 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 393
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 394 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 446
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 447 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 493
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + +P + +PE
Sbjct: 494 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPE 553
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 554 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 611
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 612 GTYTCVANTTLD 623
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 115 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 174 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 229
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 230 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 288
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 289 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 341
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 342 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 400 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 436
Score = 39.5 bits (88), Expect = 0.018
Identities = 57/237 (24%), Positives = 94/237 (39%), Gaps = 32/237 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 427 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 480
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 481 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 537
Query: 159 VNTLVSHVIVTEPKGGVK-PRVSVEQRSRRIRVGQDVRLPCAV-HAWPVPTYRWFFEHHE 216
V H+ + +P VK P +V QR G V C V H + + + +
Sbjct: 538 V-----HLEIKDPTWIVKQPEYAVVQR------GSMVSFECKVKHDHTLSLTVLWLKDNR 586
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
+L E T+ D+ L + V +D+G + C N T+ S S L V P
Sbjct: 587 ELPSDERFTV-------DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 288 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 345
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAA 132
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 62.5 bits (145), Expect = 2e-09
Identities = 77/328 (23%), Positives = 119/328 (36%), Gaps = 34/328 (10%)
Query: 41 HATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHC 97
H T YRC ++ G N+ V+ P V V E +V G AV L CV
Sbjct: 3088 HGT-YRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVKVGKAVTLECV---SA 3139
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGS--LYISAVSTSDRHNRFLCRVRDKITGI 155
+ SS W L + + L D L IS+ SD ++C ++ +
Sbjct: 3140 GEPRSSARWTRISSTPAK--LEQRTYGLMDSHTVLQISSAKPSDA-GTYVCLAQNALGTA 3196
Query: 156 RTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHH 215
+ V +V T P+V E+ + G L C+ P T W
Sbjct: 3197 QKQVEVIVD----TGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPARTIHW----- 3247
Query: 216 EQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + W+ L+ L I +V ++D+G+++C + G L V P
Sbjct: 3248 ---SKLRSPLPWQHR--LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3302
Query: 276 VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTH 335
T PE + + L C +G P W G +L P E LH +
Sbjct: 3303 ATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PGRATARNE---LLHFERAA 3358
Query: 336 KDDQGIYQCFASNARDQAYGMSEYLFDG 363
+D G Y+C +N A ++ L G
Sbjct: 3359 PEDSGRYRCRVTNKVGSAEAFAQLLVQG 3386
Score = 54.4 bits (125), Expect = 6e-07
Identities = 77/315 (24%), Positives = 112/315 (35%), Gaps = 36/315 (11%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAA--LSSPW-EVHVPDEYVIAGNAVVLRCVVPPHCA 98
A Y C + + +HV A+ LS+P +H P V G RC
Sbjct: 1837 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT---G 1893
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ EW L +K ++ G L + AV +D+ ++LCR G + A
Sbjct: 1894 SPTPTLEWTGGPG----GQLPAKA-QIHGGILRLPAVEPTDQA-QYLCRAHSS-AGQQVA 1946
Query: 159 VNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQL 218
L H GG PRV V ++ G+ VRL C P T W E L
Sbjct: 1947 RAVLHVH-------GGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE-GGSL 1998
Query: 219 TPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT 278
P R+ D L I + DAG ++C + G+ ++V
Sbjct: 1999 PP------QARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASQ 2052
Query: 279 KPEVLRSKPKS-----DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKN 333
P + S S + L+C V G V W G +L + ++ G RL +
Sbjct: 2053 PPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPHHTQVH----GSRLRLPQ 2108
Query: 334 THKDDQGIYQCFASN 348
D G Y C N
Sbjct: 2109 VSPADSGEYVCRVEN 2123
Score = 51.6 bits (118), Expect = 4e-06
Identities = 72/312 (23%), Positives = 116/312 (37%), Gaps = 34/312 (10%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHCADRISS 103
Y C S G+ + +HV S P+ VP+ + AG V L+C+ H ++
Sbjct: 3278 YICNATSPAGHAEATIILHVE---SPPYATTVPEHASVQAGETVQLQCLA--HGTPPLTF 3332
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV 163
+W + L + + L L+ + D R+ CRV +K+ LV
Sbjct: 3333 -QWSRVG--SSLPGRATARNEL----LHFERAAPEDS-GRYRCRVTNKVGSAEAFAQLLV 3384
Query: 164 S----HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT 219
+ T G P V V + +G V CAV + RWF E QL
Sbjct: 3385 QGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGG-QLP 3443
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE--PISVR 277
P + +G+L IQ + + G ++C + G L++ + +
Sbjct: 3444 P---------GHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLIN 3494
Query: 278 TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKD 337
+ V + +C G P V W G L P I++ G + I +
Sbjct: 3495 IRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPG----IVQSGGVVRIAHVELA 3550
Query: 338 DQGIYQCFASNA 349
D G Y+C A+NA
Sbjct: 3551 DAGQYRCTATNA 3562
Score = 48.8 bits (111), Expect = 3e-05
Identities = 59/238 (24%), Positives = 95/238 (39%), Gaps = 39/238 (16%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
HRL+ +L I V+ D +++C G A T++ HV P P +
Sbjct: 3258 HRLEGDTLIIPRVAQQDS-GQYICNATSP-AGHAEA--TIILHV--ESP-----PYATTV 3306
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
++ G+ V+L C H P T++W ++L RA +E LL ++
Sbjct: 3307 PEHASVQAGETVQLQCLAHGTPPLTFQW---------SRVGSSLPGRATARNE-LLHFER 3356
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEP--------------ISVRTKPEVLRSKPK 288
ED+GR+ C + N VGS L+V P +V+ P++
Sbjct: 3357 AAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIG 3416
Query: 289 SDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFA 346
+ + C V + W G L P + +DG+ L I+N + QG Y C A
Sbjct: 3417 ASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSV---QDGV-LRIQNLDQSCQGTYICQA 3470
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 5/113 (4%)
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDC 295
G++ I V DAG++ C N G+ H L+V + + + P+ +R S C
Sbjct: 3540 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV-QALPQISMPQEVRVPAGSAAVFPC 3598
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+G+P + W +L P+ R+E L + + D G Y C A+N
Sbjct: 3599 IASGYPTPDISWSKLDGSLPPDSRLE----NNMLMLPSVQPQDAGTYVCTATN 3647
Score = 44.8 bits (101), Expect = 5e-04
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 15/125 (12%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE----PISVRTKPEVLRS-KPKSDIA 292
L V+ DAG ++C N S + L+VTE PI+V + + +S +P +D+
Sbjct: 1733 LHFPSVQPSDAGVYICTCRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVT 1792
Query: 293 LDCKVNG-HPIELVYW--LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN- 348
C P + W LHNG+ P ++ +G+ L I+N D G Y C SN
Sbjct: 1793 FICTAKSKSPAYTLVWTRLHNGKL--PTRAMDF--NGI-LTIRNVQLSDAGTYVCTGSNM 1847
Query: 349 -ARDQ 352
A DQ
Sbjct: 1848 FAMDQ 1852
Score = 44.4 bits (100), Expect = 6e-04
Identities = 55/203 (27%), Positives = 83/203 (40%), Gaps = 26/203 (12%)
Query: 160 NTLVSHVIVTE-PKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAW-PVPTYRWFFEHHEQ 217
NT + ++VTE P + V EQRS+ +R G DV C + P T W H+ +
Sbjct: 1757 NTSRAELLVTEAPSKPITVTVE-EQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGK 1815
Query: 218 LTPIEETTLWKRARLLD-EGLLSIQKVRREDAGRFVCWLNNTV----GSESVHFTL--IV 270
L R +D G+L+I+ V+ DAG +VC +N G+ ++H +
Sbjct: 1816 LP----------TRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTL 1865
Query: 271 TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHN-GRTLEPNERIEILEDGLRL 329
+ P+ V P L +P C G P + W G L +I G L
Sbjct: 1866 SAPV-VSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIH----GGIL 1920
Query: 330 HIKNTHKDDQGIYQCFASNARDQ 352
+ DQ Y C A ++ Q
Sbjct: 1921 RLPAVEPTDQAQYLCRAHSSAGQ 1943
Score = 44.4 bits (100), Expect = 6e-04
Identities = 60/242 (24%), Positives = 92/242 (38%), Gaps = 28/242 (11%)
Query: 122 YHRLDDGS-LYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPK-----GGV 175
+H GS L + VS +D ++CRV + ++ V H + P G
Sbjct: 2095 HHTQVHGSRLRLPQVSPADS-GEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGST 2153
Query: 176 KPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
+P + +E S + GQ + L C V + H Q+T +
Sbjct: 2154 RP-IRIEPSSSHVAEGQTLDLNCVVPG----------QAHAQVTWHKRGGSLPARHQTHG 2202
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVG--SESVHFTL---IVTEPIS-VRTKPEVLRSKPKS 289
LL + +V D+G +VC + T G SV T+ ++ PI VR +
Sbjct: 2203 SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQ 2262
Query: 290 DIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ L C V G V W G +L ++ G RL+I D G Y C ASN
Sbjct: 2263 TLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR----GSRLYIFQASPADAGQYVCRASNG 2318
Query: 350 RD 351
+
Sbjct: 2319 ME 2320
Score = 41.9 bits (94), Expect = 0.003
Identities = 65/298 (21%), Positives = 102/298 (34%), Gaps = 35/298 (11%)
Query: 61 NIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS 120
N+ A + P + V G + L CVVP ++ T + V H
Sbjct: 2334 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQV--TWHKRGGSLPVRHQTHG 2391
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
R LY ++ + S ++CRV + +V + + P GV P V
Sbjct: 2392 SLLR-----LYQASPADS---GEYVCRVLGSSVPLEASVLVTIEPA-GSVPALGVTPTVR 2442
Query: 181 VEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSI 240
+E S ++ GQ + L C V W P R RLL
Sbjct: 2443 IESSSSQVAEGQTLDLNCLVAGQAHAQVTW--HKRGGSLPARHQVHGSRLRLL------- 2493
Query: 241 QKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS----------VRTKPEVLRSKPKSD 290
+V D+G +VC + + G++ + + + +S VR +
Sbjct: 2494 -QVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHT 2552
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L+C V + W G +L +I G RL I D G Y C SN
Sbjct: 2553 LDLNCLVASQAPHTITWYKRGGSLPSRHQIV----GSRLRIPQVTPADSGEYVCHVSN 2606
Score = 41.9 bits (94), Expect = 0.003
Identities = 73/308 (23%), Positives = 113/308 (36%), Gaps = 43/308 (13%)
Query: 59 SKNIHVYAALSSP-WEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHY 117
S +HV A +P + V G + L+CVVP +++ W H
Sbjct: 2817 SSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT---W---------HK 2864
Query: 118 LGSKY---HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTE-PKG 173
G H++ L ++ VS +D + C+V + +V + P
Sbjct: 2865 RGGNLPARHQVHGPLLRLNQVSPADS-GEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAP 2923
Query: 174 GVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
G+ + +E S + GQ + L C V W+ P T + RL
Sbjct: 2924 GLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS--LPARHQTHGSQLRL- 2980
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSES-VHFTLIV--TEPISVRTKPEVLRSKPKS- 289
V D+G +VC G E FT+ V +E S R + V+ P S
Sbjct: 2981 -------HHVSPADSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3033
Query: 290 ------DIALDCKVN--GHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGI 341
D + C ++ PI L W + LE N + I +G + I T + G
Sbjct: 3034 TVQQGQDASFKCLIHDGAAPISLE-WKTRNQELEDN--VHISPNGSIITIVGTRPSNHGT 3090
Query: 342 YQCFASNA 349
Y+C ASNA
Sbjct: 3091 YRCVASNA 3098
Score = 39.9 bits (89), Expect = 0.014
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 273 PISVRTKP-EVLRSKPKSDIALDCKVNGHPIE-LVYWLHNGRTLEPNERIEILEDGLR-- 328
P V T P E +++ + C G P L+ W N + R+ + +G R
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGT 464
Query: 329 LHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
L I++ + DQG Y C A NAR +G+ +
Sbjct: 465 LIIRDVKESDQGAYTCEAMNARGMVFGIPD 494
Score = 39.5 bits (88), Expect = 0.018
Identities = 65/297 (21%), Positives = 105/297 (35%), Gaps = 46/297 (15%)
Query: 69 SSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGS---KYHRL 125
S P + +V G + L CVVP +++ W H G YH+
Sbjct: 2728 SMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT---W---------HKRGGSLPSYHQT 2775
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLV---SHVIVTEPKGGVKPRVSVE 182
L + VS +D ++CRV + +V + V P G P + +E
Sbjct: 2776 RGSRLRLHHVSPAD-SGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2834
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S R+ GQ + L C V + H Q+T + + LL + +
Sbjct: 2835 PSSSRVAEGQTLDLKCVVPG----------QAHAQVTWHKRGGNLPARHQVHGPLLRLNQ 2884
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKP------------KSD 290
V D+G + C + + G+ L+ EP S P ++P
Sbjct: 2885 VSPADSGEYSCQVTGSSGTLEAS-VLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQT 2943
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
+ L+C V G V W G +L + G +L + + D G Y C A+
Sbjct: 2944 LDLNCVVPGQAHAQVTWYKRGGSLPARHQTH----GSQLRLHHVSPADSGEYVCRAA 2996
Score = 39.1 bits (87), Expect = 0.024
Identities = 59/240 (24%), Positives = 90/240 (37%), Gaps = 28/240 (11%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVE 182
H++ L + V+ +D ++CRV +V + + GV V +E
Sbjct: 2483 HQVHGSRLRLLQVTPADS-GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE 2541
Query: 183 QRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQK 242
S + G + L C V + T W+ P + R R I +
Sbjct: 2542 SSSASLANGHTLDLNCLVASQAPHTITWYKRGGS--LPSRHQIVGSRLR--------IPQ 2591
Query: 243 VRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS-----VRTKP--EVLRSKPK----SDI 291
V D+G +VC ++N GS +LIVT S R P + S P +
Sbjct: 2592 VTPADSGEYVCHVSNGAGSRET--SLIVTIQGSGSSHVPRVSPPIRIESSSPTVVEGQTL 2649
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARD 351
L+C V P ++ W G +L R + LRLH + D G Y C A+N D
Sbjct: 2650 DLNCVVARQPQAIITWYKRGGSLP--SRHQTHGSHLRLHQMSV--ADSGEYVCRANNNID 2705
Score = 34.3 bits (75), Expect = 0.69
Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQ 217
A T SHV++ P++S+ Q R + G PC +P P W +
Sbjct: 3562 AAGTTQSHVLLLVQ---ALPQISMPQEVR-VPAGSAAVFPCIASGYPTPDISW-SKLDGS 3616
Query: 218 LTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
L P L+ +L + V+ +DAG +VC N G L V E +
Sbjct: 3617 LPPDSR---------LENNMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQVPERV 3664
Score = 32.3 bits (70), Expect = 2.8
Identities = 50/233 (21%), Positives = 83/233 (35%), Gaps = 28/233 (12%)
Query: 123 HRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA-VNTLVSHVIVTEPKGGVKPRVSV 181
H++ L I V+ +D ++C V + T+ + T+ P+ V P + +
Sbjct: 2580 HQIVGSRLRIPQVTPADS-GEYVCHVSNGAGSRETSLIVTIQGSGSSHVPR--VSPPIRI 2636
Query: 182 EQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQ 241
E S + GQ + L C V P W+ P T RL
Sbjct: 2637 ESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGS--LPSRHQTHGSHLRL--------H 2686
Query: 242 KVRREDAGRFVCWLNNTVGSESVHFTLIVT----EPISVRTKPEVLRSKPKSDIA----- 292
++ D+G +VC NN + + + V+ P + + + S +A
Sbjct: 2687 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETL 2746
Query: 293 -LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQC 344
L+C V G V W G +L + G RL + + D G Y C
Sbjct: 2747 DLNCVVPGQAHAQVTWHKRGGSLPSYHQTR----GSRLRLHHVSPADSGEYVC 2795
>AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.
Length = 1115
Score = 62.5 bits (145), Expect = 2e-09
Identities = 79/325 (24%), Positives = 128/325 (39%), Gaps = 38/325 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA---GNAVVLRCVVP---PHCA 98
Y+C R G +A ++ L++ + + ++VI GN V+ C +P P
Sbjct: 104 YQCVARMPAGAVA---SVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQ 160
Query: 99 DRIS-STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITG-IR 156
R S EWL N Y + G+L I S D + C + +T ++
Sbjct: 161 VRYSVKQEWLEASRGN--------YLIMPSGNLQIVNASQEDE-GMYKCAAYNPVTQEVK 211
Query: 157 TAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEH 214
T+ + S + R+ ++ I V GQ + L C P P W +
Sbjct: 212 TSGS---SDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDG 268
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES---VHFTLIVT 271
T + + R L LL I ED+G + C +N VG + + + V
Sbjct: 269 -------SSVTGYNKTRFLLSNLL-IDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVF 320
Query: 272 EPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHI 331
EP V + L L C+V G+P V WL N L ++R+ + LR +
Sbjct: 321 EPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALR--V 378
Query: 332 KNTHKDDQGIYQCFASNARDQAYGM 356
+ +D+G+YQC A N A+ +
Sbjct: 379 LSMGPEDEGVYQCMAENEVGSAHAV 403
Score = 34.3 bits (75), Expect = 0.69
Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V G +++L CV R++ W D +V Y +++ +L I S D
Sbjct: 242 VTKGQSLILECVASGIPPPRVT---WAKDGS-SVTGYNKTRFLL---SNLLIDTTSEEDS 294
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+ C + + AV ++ +V V EP P V++E I GQ +L C V
Sbjct: 295 -GTYRCMADNGVGQPGAAV--ILYNVQVFEP-----PEVTMELSQLVIPWGQSAKLTCEV 346
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P P+ W P+ + +R RL L + + ED G + C N VG
Sbjct: 347 RGNPPPSVLWL----RNAVPLISS---QRLRL-SRRALRVLSMGPEDEGVYQCMAENEVG 398
Query: 261 SESVHFTLIVTEP 273
S L + P
Sbjct: 399 SAHAVVQLRTSRP 411
>AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.
Length = 1114
Score = 62.5 bits (145), Expect = 2e-09
Identities = 79/325 (24%), Positives = 128/325 (39%), Gaps = 38/325 (11%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA---GNAVVLRCVVP---PHCA 98
Y+C R G +A ++ L++ + + ++VI GN V+ C +P P
Sbjct: 104 YQCVARMPAGAVA---SVPATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQ 160
Query: 99 DRIS-STEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITG-IR 156
R S EWL N Y + G+L I S D + C + +T ++
Sbjct: 161 VRYSVKQEWLEASRGN--------YLIMPSGNLQIVNASQEDE-GMYKCAAYNPVTQEVK 211
Query: 157 TAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV--GQDVRLPCAVHAWPVPTYRWFFEH 214
T+ + S + R+ ++ I V GQ + L C P P W +
Sbjct: 212 TSGS---SDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDG 268
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSES---VHFTLIVT 271
T + + R L LL I ED+G + C +N VG + + + V
Sbjct: 269 -------SSVTGYNKTRFLLSNLL-IDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVF 320
Query: 272 EPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHI 331
EP V + L L C+V G+P V WL N L ++R+ + LR +
Sbjct: 321 EPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRRALR--V 378
Query: 332 KNTHKDDQGIYQCFASNARDQAYGM 356
+ +D+G+YQC A N A+ +
Sbjct: 379 LSMGPEDEGVYQCMAENEVGSAHAV 403
Score = 34.3 bits (75), Expect = 0.69
Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V G +++L CV R++ W D +V Y +++ +L I S D
Sbjct: 242 VTKGQSLILECVASGIPPPRVT---WAKDGS-SVTGYNKTRFLL---SNLLIDTTSEEDS 294
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+ C + + AV ++ +V V EP P V++E I GQ +L C V
Sbjct: 295 -GTYRCMADNGVGQPGAAV--ILYNVQVFEP-----PEVTMELSQLVIPWGQSAKLTCEV 346
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P P+ W P+ + +R RL L + + ED G + C N VG
Sbjct: 347 RGNPPPSVLWL----RNAVPLISS---QRLRL-SRRALRVLSMGPEDEGVYQCMAENEVG 398
Query: 261 SESVHFTLIVTEP 273
S L + P
Sbjct: 399 SAHAVVQLRTSRP 411
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 61.7 bits (143), Expect = 4e-09
Identities = 53/178 (29%), Positives = 78/178 (43%), Gaps = 12/178 (6%)
Query: 177 PRVSVEQRSR-RIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
P + E SR V + V + C P+PT +W+ + ++ ++ R ++L
Sbjct: 386 PYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWY-KDAISISRLQNP----RYKVLAS 440
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIA-LD 294
G L IQK+R ED+G F C+ +N G H L VT V T+ V + A L
Sbjct: 441 GGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILR 500
Query: 295 CKVNGHPIELVYWLHNGRTLEPNE----RIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C+V+G P + W L R +LE G L I D G Y C+A+N
Sbjct: 501 CEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG-GLQIAPVFIQDAGNYTCYAAN 557
Score = 52.8 bits (121), Expect = 2e-06
Identities = 49/158 (31%), Positives = 64/158 (40%), Gaps = 8/158 (5%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G L C V P P W E+H + + R LL+ G L I V +DAG
Sbjct: 494 GMTAILRCEVSGAPKPAITWKRENHILASG---SVRIPRFMLLESGGLQIAPVFIQDAGN 550
Query: 251 FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHP-IELVY-WL 308
+ C+ NT GS + TL V S+ PE + L C P + L Y W
Sbjct: 551 YTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWK 610
Query: 309 HNGRTLEPN--ERIEILEDGLRLHIKNTHKDDQGIYQC 344
+ L P+ RI + +DG L I T D G Y C
Sbjct: 611 KDNVALTPSSTSRIVVEKDG-SLLISQTWSGDIGDYSC 647
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 61.3 bits (142), Expect = 5e-09
Identities = 74/312 (23%), Positives = 134/312 (42%), Gaps = 31/312 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 332 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 387
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 388 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 440
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIE 222
V+ ++ EP + P ++ Q + + L CA P+PT WF +
Sbjct: 441 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWF-------KGAK 487
Query: 223 ETTLWKRARLLDE-GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPE 281
+ L + +L E G L I +++ G + C N +G L + + + +PE
Sbjct: 488 GSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPE 547
Query: 282 VLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQ 339
+ S ++ +CKV + H + L V WL + R L +ER + +D L + + DD
Sbjct: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDS 605
Query: 340 GIYQCFASNARD 351
G Y C A+ D
Sbjct: 606 GTYTCVANTTLD 617
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 109 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 167
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 168 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 223
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 224 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 282
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 283 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 335
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 336 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 393
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 394 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 430
Score = 37.5 bits (83), Expect = 0.074
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 242 KVRREDAGR--FVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
K +R AGR + +L + + V L V P + P+ P+ +I + C+ G
Sbjct: 8 KKKRLSAGRVPLILFLCQMISALEVPLDL-VQPPTITQQSPKDYIIDPRENIVIQCEAKG 66
Query: 300 HPIELVYWLHNGRTLE-PNERIEILEDG---LRLHIKNTHKDD--QGIYQCFASNARDQA 353
P W NG + + + ++ G L ++I + K + +G+YQC A N R A
Sbjct: 67 KPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA 126
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 282 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 339
Score = 34.7 bits (76), Expect = 0.52
Identities = 52/236 (22%), Positives = 93/236 (39%), Gaps = 32/236 (13%)
Query: 42 ATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDE---YVIAGNAVVLRCVVPPHCA 98
+ VY+C + GY+ + ++V L+ P + P VIA +L C
Sbjct: 421 SAVYQCNASNEYGYLLANAFVNV---LAEPPRILTPANTLYQVIANRPALLDCAF---FG 474
Query: 99 DRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTA 158
+ + EW + LH Y ++G+L I V+ D + C R+K+ +
Sbjct: 475 SPLPTIEWFKGAKGSALHE--DIYVLHENGTLEIP-VAQKDSTGTYTCVARNKLGMAKNE 531
Query: 159 VNTLVSHV--IVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHE 216
V+ + IV +P+ V R S+ +++ + L T W ++ E
Sbjct: 532 VHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSL----------TVLWLKDNRE 581
Query: 217 QLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTE 272
P +E +D+ L + V +D+G + C N T+ S S L V +
Sbjct: 582 --LPSDERFT------VDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVD 629
>BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5
protein.
Length = 847
Score = 61.3 bits (142), Expect = 5e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLI--VTEPISVRTKPEVLRSKPKSDI 291
D+G L I KV G + C+ + G E V+ T I V P +R PE +P
Sbjct: 302 DDGSLYITKVTTTHVGNYTCYAD---GYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTA 358
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+L C G P + WL NG + P ++++ + +G +HI N +D G Y C A N
Sbjct: 359 SLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKN 417
Score = 35.9 bits (79), Expect = 0.23
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 18/148 (12%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
DDGSLYI+ V+T+ N + C G T + V V P + V S
Sbjct: 302 DDGSLYITKVTTTHVGN-YTCYA----DGYEQVYQTHIFQV-------NVPPVIRVYPES 349
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVR 244
+ G L C P P W ++ +TP L K+ L G + I VR
Sbjct: 350 QAREPGVTASLRCHAEGIPKPQLGW-LKNGIDITP----KLSKQLTLQANGSEVHISNVR 404
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTE 272
ED G + C N G + +L V +
Sbjct: 405 YEDTGAYTCIAKNEAGVDEDISSLFVED 432
>AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein
protein.
Length = 773
Score = 61.3 bits (142), Expect = 5e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLI--VTEPISVRTKPEVLRSKPKSDI 291
D+G L I KV G + C+ + G E V+ T I V P +R PE +P
Sbjct: 228 DDGSLYITKVTTTHVGNYTCYAD---GYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTA 284
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+L C G P + WL NG + P ++++ + +G +HI N +D G Y C A N
Sbjct: 285 SLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKN 343
Score = 35.9 bits (79), Expect = 0.23
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 18/148 (12%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
DDGSLYI+ V+T+ N + C G T + V V P + V S
Sbjct: 228 DDGSLYITKVTTTHVGN-YTCYA----DGYEQVYQTHIFQV-------NVPPVIRVYPES 275
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVR 244
+ G L C P P W ++ +TP L K+ L G + I VR
Sbjct: 276 QAREPGVTASLRCHAEGIPKPQLGW-LKNGIDITP----KLSKQLTLQANGSEVHISNVR 330
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTE 272
ED G + C N G + +L V +
Sbjct: 331 YEDTGAYTCIAKNEAGVDEDISSLFVED 358
>AC079227-1|AAY40948.1| 274|Homo sapiens unknown protein.
Length = 274
Score = 61.3 bits (142), Expect = 5e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLI--VTEPISVRTKPEVLRSKPKSDI 291
D+G L I KV G + C+ + G E V+ T I V P +R PE +P
Sbjct: 4 DDGSLYITKVTTTHVGNYTCYAD---GYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTA 60
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+L C G P + WL NG + P ++++ + +G +HI N +D G Y C A N
Sbjct: 61 SLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKN 119
Score = 35.9 bits (79), Expect = 0.23
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 18/148 (12%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
DDGSLYI+ V+T+ N + C G T + V V P + V S
Sbjct: 4 DDGSLYITKVTTTHVGN-YTCYA----DGYEQVYQTHIFQV-------NVPPVIRVYPES 51
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVR 244
+ G L C P P W ++ +TP L K+ L G + I VR
Sbjct: 52 QAREPGVTASLRCHAEGIPKPQLGW-LKNGIDITP----KLSKQLTLQANGSEVHISNVR 106
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTE 272
ED G + C N G + +L V +
Sbjct: 107 YEDTGAYTCIAKNEAGVDEDISSLFVED 134
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 61.3 bits (142), Expect = 5e-09
Identities = 46/165 (27%), Positives = 66/165 (40%), Gaps = 10/165 (6%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
GQ V + C A P P W + + ++ + + R LL I + +G
Sbjct: 258 GQSVVMECVASADPTPFVSWVRQDGKPIST--DVIVLGRTNLL------IANAQPWHSGV 309
Query: 251 FVCWLNN--TVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWL 308
+VC N T + L V ++ PE L S C+ +G P + WL
Sbjct: 310 YVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWL 369
Query: 309 HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
HNG L PN R+++ G L I D G YQC A N+ A
Sbjct: 370 HNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMA 414
Score = 42.7 bits (96), Expect = 0.002
Identities = 31/148 (20%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 215 HEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP 273
H+ L + +LW L G S+ + G + C + +G + ++
Sbjct: 82 HDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLAT 141
Query: 274 IS-VRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIK 332
++ PE + +C + G P ++ W + TL R+ +L +G+ L I
Sbjct: 142 LADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGV-LQIL 200
Query: 333 NTHKDDQGIYQCFASNARDQAYGMSEYL 360
+ + D G Y+C A+N+ Q + L
Sbjct: 201 DVQESDAGPYRCVATNSARQHFSQEALL 228
>AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein.
Length = 850
Score = 61.3 bits (142), Expect = 5e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLI--VTEPISVRTKPEVLRSKPKSDI 291
D+G L I KV G + C+ + G E V+ T I V P +R PE +P
Sbjct: 305 DDGSLYITKVTTTHVGNYTCYAD---GYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTA 361
Query: 292 ALDCKVNGHPIELVYWLHNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+L C G P + WL NG + P ++++ + +G +HI N +D G Y C A N
Sbjct: 362 SLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKN 420
Score = 35.9 bits (79), Expect = 0.23
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 18/148 (12%)
Query: 126 DDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRS 185
DDGSLYI+ V+T+ N + C G T + V V P + V S
Sbjct: 305 DDGSLYITKVTTTHVGN-YTCYA----DGYEQVYQTHIFQV-------NVPPVIRVYPES 352
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVR 244
+ G L C P P W ++ +TP L K+ L G + I VR
Sbjct: 353 QAREPGVTASLRCHAEGIPKPQLGW-LKNGIDITP----KLSKQLTLQANGSEVHISNVR 407
Query: 245 REDAGRFVCWLNNTVGSESVHFTLIVTE 272
ED G + C N G + +L V +
Sbjct: 408 YEDTGAYTCIAKNEAGVDEDISSLFVED 435
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 60.9 bits (141), Expect = 7e-09
Identities = 85/338 (25%), Positives = 135/338 (39%), Gaps = 44/338 (13%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 110 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 168
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRD------- 150
I W+ D+ L L+ G LY S V D ++C R
Sbjct: 169 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 224
Query: 151 -------KITGIRTAVNTLVSHVIVTEPKGGVKPR------VSVE---QRSRRIRVGQDV 194
K+ + +T+ +++ TE G R ++ E +R G +
Sbjct: 225 QKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELR-GNVL 283
Query: 195 RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCW 254
L C P P W E + + P + T++K E L I V D+G + C
Sbjct: 284 SLECIAEGLPTPIIYWAKE--DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCI 336
Query: 255 LNNTVGSESVHFTLIVTEPISVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGR 312
N +G+ +H T+ V + T P+ L P D L C+ NG+P + WL NG
Sbjct: 337 AKNALGA--IHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 394
Query: 313 TLE--PNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+E P++ + DG + N + +YQC ASN
Sbjct: 395 PIEIAPDDPSRKI-DGDTIIFSNVQERSSAVYQCNASN 431
Score = 48.4 bits (110), Expect = 4e-05
Identities = 75/318 (23%), Positives = 132/318 (41%), Gaps = 43/318 (13%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIA-GNAVVLRCVVPPHCADRISS 103
Y+C ++++G I + ++ V AA P+ + P V++ G L C + RIS
Sbjct: 333 YQCIAKNALGAIHHTISVRVKAA---PYWITAPQNLVLSPGEDGTLICRANGNPKPRIS- 388
Query: 104 TEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNR-FLCRVRDKITGIRTAVNTL 162
WL + + + ++D ++ S V +R + + C ++ G A N
Sbjct: 389 --WLTNG-VPIEIAPDDPSRKIDGDTIIFSNVQ--ERSSAVYQCNASNEY-GYLLA-NAF 441
Query: 163 VSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWF-----FEHHEQ 217
V+ ++ EP + P ++ Q + + L CA P+PT WF HE
Sbjct: 442 VN--VLAEPPRILTPANTLYQ----VIANRPALLDCAFFGSPLPTIEWFKGAKGSALHED 495
Query: 218 LTPIEE--TTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
+ + E T K A + + I +++ G + C N +G
Sbjct: 496 IYVLHENGTLEIKDATWI---VKEIPVAQKDSTGTYTCVARNKLGMAKNE---------- 542
Query: 276 VRTKPEVLRSKPKSDIALDCKV-NGHPIEL-VYWLHNGRTLEPNERIEILEDGLRLHIKN 333
V +PE + S ++ +CKV + H + L V WL + R L +ER + +D L + +
Sbjct: 543 VHLQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVAD 600
Query: 334 THKDDQGIYQCFASNARD 351
DD G Y C A+ D
Sbjct: 601 VSDDDSGTYTCVANTTLD 618
Score = 39.5 bits (88), Expect = 0.018
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 21/185 (11%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
G+D L C + P P W PIE +R +D + V+ +
Sbjct: 370 GEDGTLICRANGNPKPRISWLTNG----VPIEIAPD-DPSRKIDGDTIIFSNVQERSSAV 424
Query: 251 FVCWLNNTVGSESVH-FTLIVTEPISVRTKPEVLRSKPKSDIAL-DCKVNGHPIELVYWL 308
+ C +N G + F ++ EP + T L + AL DC G P+ + W
Sbjct: 425 YQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWF 484
Query: 309 HNGRTLEPNERIEILEDGLRLHIKN----------THKDDQGIYQCFASN----ARDQAY 354
+ +E I +L + L IK+ KD G Y C A N A+++ +
Sbjct: 485 KGAKGSALHEDIYVLHENGTLEIKDATWIVKEIPVAQKDSTGTYTCVARNKLGMAKNEVH 544
Query: 355 GMSEY 359
EY
Sbjct: 545 LQPEY 549
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 283 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 340
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 37 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 96
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 97 GTLIINIMSEGKAETYEGVYQCTARNERGAA 127
>AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein.
Length = 931
Score = 60.5 bits (140), Expect = 9e-09
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGR 250
GQ + L C P P W + T + + R L LL I ED+G
Sbjct: 62 GQSLILECVASGIPPPRVTWAKDG-------SSVTGYNKTRFLLSNLL-IDTTSEEDSGT 113
Query: 251 FVCWLNNTVGSES---VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
+ C +N VG + + + V EP V + L L C+V G+P V W
Sbjct: 114 YRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLW 173
Query: 308 LHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQAYGM 356
L N L ++R+ + LR + + +D+G+YQC A N A+ +
Sbjct: 174 LRNAVPLISSQRLRLSRRALR--VLSMGPEDEGVYQCMAENEVGSAHAV 220
Score = 34.3 bits (75), Expect = 0.69
Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDR 140
V G +++L CV R++ W D +V Y +++ +L I S D
Sbjct: 59 VTKGQSLILECVASGIPPPRVT---WAKDGS-SVTGYNKTRFLL---SNLLIDTTSEEDS 111
Query: 141 HNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAV 200
+ C + + AV ++ +V V EP P V++E I GQ +L C V
Sbjct: 112 -GTYRCMADNGVGQPGAAV--ILYNVQVFEP-----PEVTMELSQLVIPWGQSAKLTCEV 163
Query: 201 HAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVG 260
P P+ W P+ + +R R L L + + ED G + C N VG
Sbjct: 164 RGNPPPSVLWL----RNAVPLISS---QRLR-LSRRALRVLSMGPEDEGVYQCMAENEVG 215
Query: 261 SESVHFTLIVTEP 273
S L + P
Sbjct: 216 SAHAVVQLRTSRP 228
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 170 EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKR 229
+P+ PR ++ + VG+D L C + P P W E +Q P+ ++
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW--EKDQQ--PVAAGARFRL 58
Query: 230 ARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT-------KPEV 282
A+ D L+I + D+G++VC N +G L V + +P
Sbjct: 59 AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTS 118
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTL----EPNERIEILEDGLRLHIKNTHKDD 338
+R + S+ C+V G P V W +GR L P R+E L + L I+ D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 339 QGIYQCFASNARDQAYGMSEYLFDGN 364
G Y+ A N A + + D +
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSD 204
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 17/192 (8%)
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ +TEPKG SV + G L C V A P W+ + ++L+ +
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQA-EAGTTAMLSCEV-AQPQTEVTWY-KDGKKLSSSSKV 1212
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-- 282
+ + L +Q+V + DAG + C G + V F L +TEP +V K ++
Sbjct: 1213 RMEVKGCTRR---LVVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH 1265
Query: 283 --LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDD 338
+R++ + L C+V E V W +G+ L + ++ I G +L ++ + D
Sbjct: 1266 NEVRTEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 339 QGIYQCFASNAR 350
G Y C A R
Sbjct: 1325 AGEYTCEAGGQR 1336
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 10/190 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
S R+ + G+ RL C V P P W + + +T +++ A+ + +L
Sbjct: 241 STGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVYEDAQ--ENFVLK 297
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVLRSKPKSDIALDCKVN 298
I ++ D G + C +N VG ++V EP + + + + L + K C+V
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEV- 356
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
P W L + + I E+G RL ++N DD +Y C + + +
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC---ETPEGSRTV 413
Query: 357 SEYLFDGNVL 366
+E GN+L
Sbjct: 414 AELAVQGNLL 423
Score = 47.2 bits (107), Expect = 9e-05
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 30/206 (14%)
Query: 174 GVKPRVSVEQRSRRIRVGQDV-RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
G P+V E R ++ G + + V +P P WF + + LT + + L
Sbjct: 5257 GQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTASAHIRMTDKKIL 5315
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP-----EVL---- 283
L I V RED+G++ +++N +G+ L+V P KP E L
Sbjct: 5316 ---HTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372
Query: 284 ---RSKPK-----SDIALDCKVNGHPIELVYWLHNGRT-----LEPNERIEILEDGLRLH 330
R PK S I KV G P+ V+WL + P+ + + H
Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432
Query: 331 ---IKNTHKDDQGIYQCFASNARDQA 353
+ + + QG Y C ASNA QA
Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQA 5458
Score = 47.2 bits (107), Expect = 9e-05
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 15/177 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHE-QLTP---IEETTLWKRARLLDEGLLSIQKVRR 245
+G+ V+L C V P P W+ + Q+ P + E A +LD S+ V
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILD----SLTGV-- 6080
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
D+G+++C+ + G+ S ++V P K D C + G P +
Sbjct: 6081 -DSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQI 6139
Query: 306 YWLHNGRTLEPNERIEILEDG----LRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G L + + L + L L I+ K+D G+Y+C N A +E
Sbjct: 6140 RWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Score = 44.4 bits (100), Expect = 6e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILED---GLRLHIKNTHKDDQGIYQCFAS 347
++ DC V G P+ V W +G+ LE ++ I ED G +L I D G+Y+C A
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 348 NA 349
N+
Sbjct: 5203 NS 5204
Score = 41.1 bits (92), Expect = 0.006
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFT--LIVTE-PISVRTKPEVLRSKPKSDIALD 294
L++ +R ED+G V +E VH + L+VTE P+S + + + K + L+
Sbjct: 2133 LTLSGLRPEDSGLMV------FKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLE 2186
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQ 352
C+++ ++ V WL +G L + + I G L I DQG+Y C A +A+
Sbjct: 2187 CELSRPNVD-VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSS 2245
Query: 353 A 353
A
Sbjct: 2246 A 2246
Score = 40.7 bits (91), Expect = 0.008
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
KV G+P +YW +G+ L + I + + + L I + ++D G Y + SNA A
Sbjct: 5283 KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 354 YGMSEYLFDG 363
Y + L G
Sbjct: 5343 YSSARLLVRG 5352
Score = 39.9 bits (89), Expect = 0.014
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK-RARLL 233
V PR + R+ G+D + C + P P RW+ + T + TL + R+ LL
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+L I+ +ED G + C L N +GS L + P+
Sbjct: 6166 ---VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPM 6203
Score = 39.1 bits (87), Expect = 0.024
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNAR 350
L+C+V+ + V W + L+P + E++ DGL +L I + H +D+ Y C A + +
Sbjct: 2309 LECQVSRASAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 351 DQA 353
A
Sbjct: 2368 TSA 2370
Score = 38.7 bits (86), Expect = 0.032
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 305 VYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQAYGMS 357
V WL +GRTL P + E+ R L +++ +DD G+Y+C + R AY +S
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR-IAYQLS 790
Score = 38.7 bits (86), Expect = 0.032
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 228 KRARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR 284
KR +++ EG L++ +R EDAG +VC + S T+ V + + +
Sbjct: 1852 KRFQMVAEGPVRSLTVLGLRAEDAGEYVC--ESRDDHTSAQLTVSVPRVVKFMSGLSTVV 1909
Query: 285 SKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIY 342
++ + C V+ + +V W +G L+P+E+ I + G L I + +D G
Sbjct: 1910 AEEGGEATFQCVVSPSDVAVV-WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQI 1968
Query: 343 QCFASNARDQA 353
A A A
Sbjct: 1969 TVEAEGASSSA 1979
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT-EPISVRTKPEVLRSKPKSDIALDCK 296
L +Q ++RED G + C T GS++ TL VT P+ + + L C+
Sbjct: 3946 LVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCE 4001
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
++ V W L P + ++++DG L ++ ++D G Y C + + A
Sbjct: 4002 LSRAGAS-VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDC 295
+L I+ +DAG + C + + + S+H V E + T+ L+ + K C
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLH----VEEKANCFTEELTNLQVEEKGTAVFTC 2937
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
K HP V W L + + + ++G LRL I K D Y C A+ +A
Sbjct: 2938 KTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRA 2996
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I + DAG ++C G E TL + + R +V + + + L C
Sbjct: 3505 LQICGLAMADAGEYLC----VCGQERTSATLTI-RALPARFIEDVKNQEAREGATAVLQC 3559
Query: 296 KVNGH-PIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
++N P+E W TL +R + +DG + L I+ D G Y C R
Sbjct: 3560 ELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTS 3616
Query: 353 A 353
A
Sbjct: 3617 A 3617
Score = 32.7 bits (71), Expect = 2.1
Identities = 28/121 (23%), Positives = 46/121 (38%), Gaps = 9/121 (7%)
Query: 229 RARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
R +L EG L I +D+GR+ C S V + P+ + + L
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR---VHARPVRFQEALKDLEV 3196
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQ 343
L C ++ V W + L P ++ + ++G L L ++N D G Y
Sbjct: 3197 LEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Query: 344 C 344
C
Sbjct: 3256 C 3256
Score = 32.7 bits (71), Expect = 2.1
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDCK 296
L I ++ +D G + C G + +L VTEP + V D+ C+
Sbjct: 4126 LLIHQLEAKDTGEYAC----VTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCE 4181
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEI-LEDGLRLH---IKNTHKDDQGIYQCFASNARDQ 352
V+ V W G L+ NE E+ + DG R+H +K +D G N
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDG-RIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 353 A 353
A
Sbjct: 4241 A 4241
Score = 32.3 bits (70), Expect = 2.8
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L ++ V +EDAG + C +T S+ ++ V P +T+ + L + L C++
Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMASL--SVRVPRP-KFKTRLQSLEQETGDIARLCCQL 4091
Query: 298 -NGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
+ +V WL G L + E+ G L I D G Y C + A
Sbjct: 4092 SDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAA 4150
Score = 31.9 bits (69), Expect = 3.7
Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I+ + DAG + C G E TL V + R +V + + + L C
Sbjct: 3769 LQIRGLAVVDAGEYSC----VCGQERTSATLTV-RALPARFIEDVKNQEAREGATAVLQC 3823
Query: 296 KVN-GHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
+++ P+E W TL +R + +DG R L I D G Y C R
Sbjct: 3824 ELSKAAPVE---WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTS 3880
Query: 353 A 353
A
Sbjct: 3881 A 3881
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKS-DIALDCKVNGHPIELVYWLHNGRTLEPNE 318
G + L VTE SV ++ + + D+ L C+ + I V W +G+TL +
Sbjct: 3081 GDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA 3139
Query: 319 RIEILEDGLR--LHIKNTHKDDQGIYQCFASNA 349
R ++ +G R L I D G Y+C A A
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGA 3172
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 170 EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKR 229
+P+ PR ++ + VG+D L C + P P W E +Q P+ ++
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW--EKDQQ--PVAAGARFRL 58
Query: 230 ARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT-------KPEV 282
A+ D L+I + D+G++VC N +G L V + +P
Sbjct: 59 AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTS 118
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTL----EPNERIEILEDGLRLHIKNTHKDD 338
+R + S+ C+V G P V W +GR L P R+E L + L I+ D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 339 QGIYQCFASNARDQAYGMSEYLFDGN 364
G Y+ A N A + + D +
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSD 204
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 17/192 (8%)
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ +TEPKG SV + G L C V A P W+ + ++L+ +
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQA-EAGTTAMLSCEV-AQPQTEVTWY-KDGKKLSSSSKV 1212
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-- 282
+ + L +Q+V + DAG + C G + V F L +TEP +V K ++
Sbjct: 1213 RMEVKGCTRR---LVVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH 1265
Query: 283 --LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDD 338
+R++ + L C+V E V W +G+ L + ++ I G +L ++ + D
Sbjct: 1266 NEVRTEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 339 QGIYQCFASNAR 350
G Y C A R
Sbjct: 1325 AGEYTCEAGGQR 1336
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 10/190 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
S R+ + G+ RL C V P P W + + +T +++ A+ + +L
Sbjct: 241 STGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVYEDAQ--ENFVLK 297
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVLRSKPKSDIALDCKVN 298
I ++ D G + C +N VG ++V EP + + + + L + K C+V
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEV- 356
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
P W L + + I E+G RL ++N DD +Y C + + +
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC---ETPEGSRTV 413
Query: 357 SEYLFDGNVL 366
+E GN+L
Sbjct: 414 AELAVQGNLL 423
Score = 47.2 bits (107), Expect = 9e-05
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 30/206 (14%)
Query: 174 GVKPRVSVEQRSRRIRVGQDV-RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
G P+V E R ++ G + + V +P P WF + + LT + + L
Sbjct: 5257 GQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTASAHIRMTDKKIL 5315
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP-----EVL---- 283
L I V RED+G++ +++N +G+ L+V P KP E L
Sbjct: 5316 ---HTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372
Query: 284 ---RSKPK-----SDIALDCKVNGHPIELVYWLHNGRT-----LEPNERIEILEDGLRLH 330
R PK S I KV G P+ V+WL + P+ + + H
Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432
Query: 331 ---IKNTHKDDQGIYQCFASNARDQA 353
+ + + QG Y C ASNA QA
Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQA 5458
Score = 47.2 bits (107), Expect = 9e-05
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 15/177 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHE-QLTP---IEETTLWKRARLLDEGLLSIQKVRR 245
+G+ V+L C V P P W+ + Q+ P + E A +LD S+ V
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILD----SLTGV-- 6080
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
D+G+++C+ + G+ S ++V P K D C + G P +
Sbjct: 6081 -DSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQI 6139
Query: 306 YWLHNGRTLEPNERIEILEDG----LRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G L + + L + L L I+ K+D G+Y+C N A +E
Sbjct: 6140 RWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Score = 44.4 bits (100), Expect = 6e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILED---GLRLHIKNTHKDDQGIYQCFAS 347
++ DC V G P+ V W +G+ LE ++ I ED G +L I D G+Y+C A
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 348 NA 349
N+
Sbjct: 5203 NS 5204
Score = 41.1 bits (92), Expect = 0.006
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFT--LIVTE-PISVRTKPEVLRSKPKSDIALD 294
L++ +R ED+G V +E VH + L+VTE P+S + + + K + L+
Sbjct: 2133 LTLSGLRPEDSGLMV------FKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLE 2186
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQ 352
C+++ ++ V WL +G L + + I G L I DQG+Y C A +A+
Sbjct: 2187 CELSRPNVD-VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSS 2245
Query: 353 A 353
A
Sbjct: 2246 A 2246
Score = 40.7 bits (91), Expect = 0.008
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
KV G+P +YW +G+ L + I + + + L I + ++D G Y + SNA A
Sbjct: 5283 KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 354 YGMSEYLFDG 363
Y + L G
Sbjct: 5343 YSSARLLVRG 5352
Score = 39.9 bits (89), Expect = 0.014
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK-RARLL 233
V PR + R+ G+D + C + P P RW+ + T + TL + R+ LL
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+L I+ +ED G + C L N +GS L + P+
Sbjct: 6166 ---VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPM 6203
Score = 39.1 bits (87), Expect = 0.024
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNAR 350
L+C+V+ + V W + L+P + E++ DGL +L I + H +D+ Y C A + +
Sbjct: 2309 LECQVSRASAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 351 DQA 353
A
Sbjct: 2368 TSA 2370
Score = 38.7 bits (86), Expect = 0.032
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 305 VYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQAYGMS 357
V WL +GRTL P + E+ R L +++ +DD G+Y+C + R AY +S
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR-IAYQLS 790
Score = 38.7 bits (86), Expect = 0.032
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 228 KRARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR 284
KR +++ EG L++ +R EDAG +VC + S T+ V + + +
Sbjct: 1852 KRFQMVAEGPVRSLTVLGLRAEDAGEYVC--ESRDDHTSAQLTVSVPRVVKFMSGLSTVV 1909
Query: 285 SKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIY 342
++ + C V+ + +V W +G L+P+E+ I + G L I + +D G
Sbjct: 1910 AEEGGEATFQCVVSPSDVAVV-WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQI 1968
Query: 343 QCFASNARDQA 353
A A A
Sbjct: 1969 TVEAEGASSSA 1979
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT-EPISVRTKPEVLRSKPKSDIALDCK 296
L +Q ++RED G + C T GS++ TL VT P+ + + L C+
Sbjct: 3946 LVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCE 4001
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
++ V W L P + ++++DG L ++ ++D G Y C + + A
Sbjct: 4002 LSRAGAS-VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDC 295
+L I+ +DAG + C + + + S+H V E + T+ L+ + K C
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLH----VEEKANCFTEELTNLQVEEKGTAVFTC 2937
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
K HP V W L + + + ++G LRL I K D Y C A+ +A
Sbjct: 2938 KTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRA 2996
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I + DAG ++C G E TL + + R +V + + + L C
Sbjct: 3505 LQICGLAMADAGEYLC----VCGQERTSATLTI-RALPARFIEDVKNQEAREGATAVLQC 3559
Query: 296 KVNGH-PIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
++N P+E W TL +R + +DG + L I+ D G Y C R
Sbjct: 3560 ELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTS 3616
Query: 353 A 353
A
Sbjct: 3617 A 3617
Score = 32.7 bits (71), Expect = 2.1
Identities = 28/121 (23%), Positives = 46/121 (38%), Gaps = 9/121 (7%)
Query: 229 RARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
R +L EG L I +D+GR+ C S V + P+ + + L
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR---VHARPVRFQEALKDLEV 3196
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQ 343
L C ++ V W + L P ++ + ++G L L ++N D G Y
Sbjct: 3197 LEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Query: 344 C 344
C
Sbjct: 3256 C 3256
Score = 32.7 bits (71), Expect = 2.1
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDCK 296
L I ++ +D G + C G + +L VTEP + V D+ C+
Sbjct: 4126 LLIHQLEAKDTGEYAC----VTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCE 4181
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEI-LEDGLRLH---IKNTHKDDQGIYQCFASNARDQ 352
V+ V W G L+ NE E+ + DG R+H +K +D G N
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDG-RIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 353 A 353
A
Sbjct: 4241 A 4241
Score = 32.3 bits (70), Expect = 2.8
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L ++ V +EDAG + C +T S+ ++ V P +T+ + L + L C++
Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMASL--SVRVPRP-KFKTRLQSLEQETGDIARLCCQL 4091
Query: 298 -NGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
+ +V WL G L + E+ G L I D G Y C + A
Sbjct: 4092 SDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAA 4150
Score = 31.9 bits (69), Expect = 3.7
Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I+ + DAG + C G E TL V + R +V + + + L C
Sbjct: 3769 LQIRGLAVVDAGEYSC----VCGQERTSATLTV-RALPARFIEDVKNQEAREGATAVLQC 3823
Query: 296 KVN-GHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
+++ P+E W TL +R + +DG R L I D G Y C R
Sbjct: 3824 ELSKAAPVE---WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTS 3880
Query: 353 A 353
A
Sbjct: 3881 A 3881
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKS-DIALDCKVNGHPIELVYWLHNGRTLEPNE 318
G + L VTE SV ++ + + D+ L C+ + I V W +G+TL +
Sbjct: 3081 GDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA 3139
Query: 319 RIEILEDGLR--LHIKNTHKDDQGIYQCFASNA 349
R ++ +G R L I D G Y+C A A
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGA 3172
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 170 EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKR 229
+P+ PR ++ + VG+D L C + P P W E +Q P+ ++
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW--EKDQQ--PVAAGARFRL 58
Query: 230 ARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT-------KPEV 282
A+ D L+I + D+G++VC N +G L V + +P
Sbjct: 59 AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTS 118
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTL----EPNERIEILEDGLRLHIKNTHKDD 338
+R + S+ C+V G P V W +GR L P R+E L + L I+ D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 339 QGIYQCFASNARDQAYGMSEYLFDGN 364
G Y+ A N A + + D +
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSD 204
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 17/192 (8%)
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ +TEPKG SV + G L C V A P W+ + ++L+ +
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQA-EAGTTAMLSCEV-AQPQTEVTWY-KDGKKLSSSSKV 1212
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-- 282
+ + L +Q+V + DAG + C G + V F L +TEP +V K ++
Sbjct: 1213 RMEVKGCTRR---LVVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH 1265
Query: 283 --LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDD 338
+R++ + L C+V E V W +G+ L + ++ I G +L ++ + D
Sbjct: 1266 NEVRTEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 339 QGIYQCFASNAR 350
G Y C A R
Sbjct: 1325 AGEYTCEAGGQR 1336
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 10/190 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
S R+ + G+ RL C V P P W + + +T +++ A+ + +L
Sbjct: 241 STGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVYEDAQ--ENFVLK 297
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVLRSKPKSDIALDCKVN 298
I ++ D G + C +N VG ++V EP + + + + L + K C+V
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEV- 356
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
P W L + + I E+G RL ++N DD +Y C + + +
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC---ETPEGSRTV 413
Query: 357 SEYLFDGNVL 366
+E GN+L
Sbjct: 414 AELAVQGNLL 423
Score = 47.2 bits (107), Expect = 9e-05
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 30/206 (14%)
Query: 174 GVKPRVSVEQRSRRIRVGQDV-RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
G P+V E R ++ G + + V +P P WF + + LT + + L
Sbjct: 5257 GQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTASAHIRMTDKKIL 5315
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP-----EVL---- 283
L I V RED+G++ +++N +G+ L+V P KP E L
Sbjct: 5316 ---HTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372
Query: 284 ---RSKPK-----SDIALDCKVNGHPIELVYWLHNGRT-----LEPNERIEILEDGLRLH 330
R PK S I KV G P+ V+WL + P+ + + H
Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432
Query: 331 ---IKNTHKDDQGIYQCFASNARDQA 353
+ + + QG Y C ASNA QA
Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQA 5458
Score = 47.2 bits (107), Expect = 9e-05
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 15/177 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHE-QLTP---IEETTLWKRARLLDEGLLSIQKVRR 245
+G+ V+L C V P P W+ + Q+ P + E A +LD S+ V
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILD----SLTGV-- 6080
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
D+G+++C+ + G+ S ++V P K D C + G P +
Sbjct: 6081 -DSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQI 6139
Query: 306 YWLHNGRTLEPNERIEILEDG----LRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G L + + L + L L I+ K+D G+Y+C N A +E
Sbjct: 6140 RWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Score = 44.4 bits (100), Expect = 6e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILED---GLRLHIKNTHKDDQGIYQCFAS 347
++ DC V G P+ V W +G+ LE ++ I ED G +L I D G+Y+C A
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 348 NA 349
N+
Sbjct: 5203 NS 5204
Score = 41.1 bits (92), Expect = 0.006
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFT--LIVTE-PISVRTKPEVLRSKPKSDIALD 294
L++ +R ED+G V +E VH + L+VTE P+S + + + K + L+
Sbjct: 2133 LTLSGLRPEDSGLMV------FKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLE 2186
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQ 352
C+++ ++ V WL +G L + + I G L I DQG+Y C A +A+
Sbjct: 2187 CELSRPNVD-VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSS 2245
Query: 353 A 353
A
Sbjct: 2246 A 2246
Score = 40.7 bits (91), Expect = 0.008
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
KV G+P +YW +G+ L + I + + + L I + ++D G Y + SNA A
Sbjct: 5283 KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 354 YGMSEYLFDG 363
Y + L G
Sbjct: 5343 YSSARLLVRG 5352
Score = 39.9 bits (89), Expect = 0.014
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 175 VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK-RARLL 233
V PR + R+ G+D + C + P P RW+ + T + TL + R+ LL
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+L I+ +ED G + C L N +GS L + P+
Sbjct: 6166 ---VLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPM 6203
Score = 39.1 bits (87), Expect = 0.024
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNAR 350
L+C+V+ + V W + L+P + E++ DGL +L I + H +D+ Y C A + +
Sbjct: 2309 LECQVSRASAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 351 DQA 353
A
Sbjct: 2368 TSA 2370
Score = 38.7 bits (86), Expect = 0.032
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 305 VYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQAYGMS 357
V WL +GRTL P + E+ R L +++ +DD G+Y+C + R AY +S
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR-IAYQLS 790
Score = 38.7 bits (86), Expect = 0.032
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 228 KRARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR 284
KR +++ EG L++ +R EDAG +VC + S T+ V + + +
Sbjct: 1852 KRFQMVAEGPVRSLTVLGLRAEDAGEYVC--ESRDDHTSAQLTVSVPRVVKFMSGLSTVV 1909
Query: 285 SKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIY 342
++ + C V+ + +V W +G L+P+E+ I + G L I + +D G
Sbjct: 1910 AEEGGEATFQCVVSPSDVAVV-WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQI 1968
Query: 343 QCFASNARDQA 353
A A A
Sbjct: 1969 TVEAEGASSSA 1979
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT-EPISVRTKPEVLRSKPKSDIALDCK 296
L +Q ++RED G + C T GS++ TL VT P+ + + L C+
Sbjct: 3946 LVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCE 4001
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
++ V W L P + ++++DG L ++ ++D G Y C + + A
Sbjct: 4002 LSRAGAS-VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDC 295
+L I+ +DAG + C + + + S+H V E + T+ L+ + K C
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLH----VEEKANCFTEELTNLQVEEKGTAVFTC 2937
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
K HP V W L + + + ++G LRL I K D Y C A+ +A
Sbjct: 2938 KTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRA 2996
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I + DAG ++C G E TL + + R +V + + + L C
Sbjct: 3505 LQICGLAMADAGEYLC----VCGQERTSATLTI-RALPARFIEDVKNQEAREGATAVLQC 3559
Query: 296 KVNGH-PIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
++N P+E W TL +R + +DG + L I+ D G Y C R
Sbjct: 3560 ELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTS 3616
Query: 353 A 353
A
Sbjct: 3617 A 3617
Score = 32.7 bits (71), Expect = 2.1
Identities = 28/121 (23%), Positives = 46/121 (38%), Gaps = 9/121 (7%)
Query: 229 RARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
R +L EG L I +D+GR+ C S V + P+ + + L
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR---VHARPVRFQEALKDLEV 3196
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQ 343
L C ++ V W + L P ++ + ++G L L ++N D G Y
Sbjct: 3197 LEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Query: 344 C 344
C
Sbjct: 3256 C 3256
Score = 32.7 bits (71), Expect = 2.1
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDCK 296
L I ++ +D G + C G + +L VTEP + V D+ C+
Sbjct: 4126 LLIHQLEAKDTGEYAC----VTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCE 4181
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEI-LEDGLRLH---IKNTHKDDQGIYQCFASNARDQ 352
V+ V W G L+ NE E+ + DG R+H +K +D G N
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDG-RIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 353 A 353
A
Sbjct: 4241 A 4241
Score = 32.3 bits (70), Expect = 2.8
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L ++ V +EDAG + C +T S+ ++ V P +T+ + L + L C++
Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMASL--SVRVPRP-KFKTRLQSLEQETGDIARLCCQL 4091
Query: 298 -NGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
+ +V WL G L + E+ G L I D G Y C + A
Sbjct: 4092 SDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAA 4150
Score = 31.9 bits (69), Expect = 3.7
Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I+ + DAG + C G E TL V + R +V + + + L C
Sbjct: 3769 LQIRGLAVVDAGEYSC----VCGQERTSATLTV-RALPARFIEDVKNQEAREGATAVLQC 3823
Query: 296 KVN-GHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
+++ P+E W TL +R + +DG R L I D G Y C R
Sbjct: 3824 ELSKAAPVE---WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTS 3880
Query: 353 A 353
A
Sbjct: 3881 A 3881
Score = 31.5 bits (68), Expect = 4.9
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 260 GSESVHFTLIVTEPISVRTKPEVLRSKPKS-DIALDCKVNGHPIELVYWLHNGRTLEPNE 318
G + L VTE SV ++ + + D+ L C+ + I V W +G+TL +
Sbjct: 3081 GDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA 3139
Query: 319 RIEILEDGLR--LHIKNTHKDDQGIYQCFASNA 349
R ++ +G R L I D G Y+C A A
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGA 3172
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 15/206 (7%)
Query: 170 EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKR 229
+P+ PR ++ + VG+D L C + P P W E +Q P+ ++
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSW--EKDQQ--PVTAGARFRL 58
Query: 230 ARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT-------KPEV 282
A+ D L+I + D+G++VC N +G L V + +P
Sbjct: 59 AQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTS 118
Query: 283 LRSKPKSDIALDCKVNGHPIELVYWLHNGRTL----EPNERIEILEDGLRLHIKNTHKDD 338
+R + S+ C+V G P V W +GR L P R+E L + L I+ D
Sbjct: 119 IRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRD 178
Query: 339 QGIYQCFASNARDQAYGMSEYLFDGN 364
G Y+ A N A + + D +
Sbjct: 179 GGTYEVRAENPLGAASAAAALVVDSD 204
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 17/192 (8%)
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEET 224
H+ +TEPKG SV + G L C V A P W+ + ++L+ +
Sbjct: 1156 HLHITEPKGVFAKEQSVHNEVQA-EAGTTAMLSCEV-AQPQTEVTWY-KDGKKLSSSSKV 1212
Query: 225 TLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-- 282
+ + L +Q+V + DAG + C G + V F L +TEP +V K ++
Sbjct: 1213 RMEVKGCTRR---LVVQQVGKADAGEYSC----EAGGQRVSFQLHITEPKAVFAKEQLVH 1265
Query: 283 --LRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDD 338
+R++ + L C+V E V W +G+ L + ++ I G +L ++ + D
Sbjct: 1266 NEVRTEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQAD 1324
Query: 339 QGIYQCFASNAR 350
G Y C A R
Sbjct: 1325 AGEYTCEAGGQR 1336
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 10/190 (5%)
Query: 180 SVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLS 239
S R+ + G+ RL C V P P W + + +T +++ A+ + +L
Sbjct: 241 STGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVYEDAQ--ENFVLK 297
Query: 240 IQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEP-ISVRTKPEVLRSKPKSDIALDCKVN 298
I ++ D G + C +N VG ++V EP + + + + L + K C+V
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEV- 356
Query: 299 GHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQAYGM 356
P W L + + I E+G RL ++N DD +Y C + + +
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC---ETPEGSRTV 413
Query: 357 SEYLFDGNVL 366
+E GN+L
Sbjct: 414 AELAVQGNLL 423
Score = 47.2 bits (107), Expect = 9e-05
Identities = 54/206 (26%), Positives = 82/206 (39%), Gaps = 30/206 (14%)
Query: 174 GVKPRVSVEQRSRRIRVGQDV-RLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARL 232
G P+V E R ++ G + + V +P P WF + + LT + + L
Sbjct: 5257 GQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWF-KDGQPLTASAHIRMTDKKIL 5315
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKP-----EVL---- 283
L I V RED+G++ +++N +G+ L+V P KP E L
Sbjct: 5316 ---HTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372
Query: 284 ---RSKPK-----SDIALDCKVNGHPIELVYWLHNGRT-----LEPNERIEILEDGLRLH 330
R PK S I KV G P+ V+WL + P+ + + H
Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432
Query: 331 ---IKNTHKDDQGIYQCFASNARDQA 353
+ + + QG Y C ASNA QA
Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQA 5458
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 15/177 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHE-QLTP---IEETTLWKRARLLDEGLLSIQKVRR 245
+G+ V+L C V P P W+ + Q+ P + E A +LD S+ V
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILD----SLTGV-- 6080
Query: 246 EDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELV 305
D+G+++C+ + G+ S ++V P K D C + G P +
Sbjct: 6081 -DSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQI 6139
Query: 306 YWLHNGRTLEPNERIEILEDG----LRLHIKNTHKDDQGIYQCFASNARDQAYGMSE 358
W +G L + + L + L L I+ K+D G+Y+C N A +E
Sbjct: 6140 RWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Score = 44.4 bits (100), Expect = 6e-04
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILED---GLRLHIKNTHKDDQGIYQCFAS 347
++ DC V G P+ V W +G+ LE ++ I ED G +L I D G+Y+C A
Sbjct: 5143 VSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAE 5202
Query: 348 NA 349
N+
Sbjct: 5203 NS 5204
Score = 41.1 bits (92), Expect = 0.006
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFT--LIVTE-PISVRTKPEVLRSKPKSDIALD 294
L++ +R ED+G V +E VH + L+VTE P+S + + + K + L+
Sbjct: 2133 LTLSGLRPEDSGLMV------FKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLE 2186
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQ 352
C+++ ++ V WL +G L + + I G L I DQG+Y C A +A+
Sbjct: 2187 CELSRPNVD-VRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSS 2245
Query: 353 A 353
A
Sbjct: 2246 A 2246
Score = 40.7 bits (91), Expect = 0.008
Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%)
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
KV G+P +YW +G+ L + I + + + L I + ++D G Y + SNA A
Sbjct: 5283 KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 354 YGMSEYLFDG 363
Y + L G
Sbjct: 5343 YSSARLLVRG 5352
Score = 39.1 bits (87), Expect = 0.024
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNAR 350
L+C+V+ + V W + L+P + E++ DGL +L I + H +D+ Y C A + +
Sbjct: 2309 LECQVSRASAQ-VRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGDVK 2367
Query: 351 DQA 353
A
Sbjct: 2368 TSA 2370
Score = 38.7 bits (86), Expect = 0.032
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 305 VYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQAYGMS 357
V WL +GRTL P + E+ R L +++ +DD G+Y+C + R AY +S
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR-IAYQLS 790
Score = 38.7 bits (86), Expect = 0.032
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 228 KRARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLR 284
KR +++ EG L++ +R EDAG +VC + S T+ V + + +
Sbjct: 1852 KRFQMVAEGPVRSLTVLGLRAEDAGEYVC--ESRDDHTSAQLTVSVPRVVKFMSGLSTVV 1909
Query: 285 SKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIY 342
++ + C V+ + +V W +G L+P+E+ I + G L I + +D G
Sbjct: 1910 AEEGGEATFQCVVSPSDVAVV-WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQI 1968
Query: 343 QCFASNARDQA 353
A A A
Sbjct: 1969 TVEAEGASSSA 1979
Score = 37.5 bits (83), Expect = 0.074
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 191 GQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWK-RARLLDEGLLSIQKVRREDAG 249
G+D + C + P P RW+ + T + TL + R+ LL +L I+ +ED G
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL---VLVIRAASKEDLG 6178
Query: 250 RFVCWLNNTVGSESVHFTLIVTEPI 274
+ C L N +GS L + P+
Sbjct: 6179 LYECELVNRLGSARASAELRIQSPM 6203
Score = 37.1 bits (82), Expect = 0.098
Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 8/119 (6%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVT-EPISVRTKPEVLRSKPKSDIALDCK 296
L +Q ++RED G + C T GS++ TL VT P+ + + L C+
Sbjct: 3946 LVLQDLQREDTGEYTC----TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCE 4001
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
++ V W L P + ++++DG L ++ ++D G Y C + + A
Sbjct: 4002 LSRAGAS-VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMA 4059
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDC 295
+L I+ +DAG + C + + + S+H V E + T+ L+ + K C
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLH----VEEKANCFTEELTNLQVEEKGTAVFTC 2937
Query: 296 KVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQCFASNARDQA 353
K HP V W L + + + ++G LRL I K D Y C A+ +A
Sbjct: 2938 KTE-HPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRA 2996
Score = 34.7 bits (76), Expect = 0.52
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I + DAG ++C G E TL + + R +V + + + L C
Sbjct: 3505 LQICGLAMADAGEYLC----VCGQERTSATLTI-RALPARFIEDVKNQEAREGATAVLQC 3559
Query: 296 KVNGH-PIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
++N P+E W TL +R + +DG + L I+ D G Y C R
Sbjct: 3560 ELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTS 3616
Query: 353 A 353
A
Sbjct: 3617 A 3617
Score = 32.7 bits (71), Expect = 2.1
Identities = 28/121 (23%), Positives = 46/121 (38%), Gaps = 9/121 (7%)
Query: 229 RARLLDEG---LLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRS 285
R +L EG L I +D+GR+ C S V + P+ + + L
Sbjct: 3140 RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVR---VHARPVRFQEALKDLEV 3196
Query: 286 KPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDG--LRLHIKNTHKDDQGIYQ 343
L C ++ V W + L P ++ + ++G L L ++N D G Y
Sbjct: 3197 LEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYS 3255
Query: 344 C 344
C
Sbjct: 3256 C 3256
Score = 32.7 bits (71), Expect = 2.1
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEV-LRSKPKSDIALDCK 296
L I ++ +D G + C G + +L VTEP + V D+ C+
Sbjct: 4126 LLIHQLEAKDTGEYAC----VTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCE 4181
Query: 297 VNGHPIELVYWLHNGRTLEPNERIEI-LEDGLRLH---IKNTHKDDQGIYQCFASNARDQ 352
V+ V W G L+ NE E+ + DG R+H +K +D G N
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDG-RIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 353 A 353
A
Sbjct: 4241 A 4241
Score = 32.3 bits (70), Expect = 2.8
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKV 297
L ++ V +EDAG + C +T S+ ++ V P +T+ + L + L C++
Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMASL--SVRVPRP-KFKTRLQSLEQETGDIARLCCQL 4091
Query: 298 -NGHPIELVYWLHNGRTLEPNERIEILEDGL--RLHIKNTHKDDQGIYQCFASNARDQA 353
+ +V WL G L + E+ G L I D G Y C + A
Sbjct: 4092 SDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAA 4150
Score = 31.9 bits (69), Expect = 3.7
Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 13/121 (10%)
Query: 238 LSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPK--SDIALDC 295
L I+ + DAG + C G E TL V + R +V + + + L C
Sbjct: 3769 LQIRGLAVVDAGEYSC----VCGQERTSATLTV-RALPARFIEDVKNQEAREGATAVLQC 3823
Query: 296 KVN-GHPIELVYWLHNGRTLEPNERIEILEDGLR--LHIKNTHKDDQGIYQCFASNARDQ 352
+++ P+E W TL +R + +DG R L I D G Y C R
Sbjct: 3824 ELSKAAPVE---WRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTS 3880
Query: 353 A 353
A
Sbjct: 3881 A 3881
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 58.8 bits (136), Expect = 3e-08
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 9/168 (5%)
Query: 194 VRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLLSIQKVRREDAGRFV 252
V C P P W E + L + R + G L+I V+R D G ++
Sbjct: 3 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 62
Query: 253 CWLNNTVGSESVHFTLIVTEPISVRTKPEVLRSKPKSDIALD------CKVNGHPIELVY 306
C N GS L VT+ I+ R P + + +A+D C G P+ +
Sbjct: 63 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 122
Query: 307 WLHNGRTLEPNE-RIEILEDGLRLHIKNTHKDDQGIYQCFASNARDQA 353
W +G + + RI+ LE+G+ L I+ D G Y C AS +A
Sbjct: 123 WRKDGVLVSTQDSRIKQLENGV-LQIRYAKLGDTGRYTCIASTPSGEA 169
>AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein.
Length = 383
Score = 58.0 bits (134), Expect = 5e-08
Identities = 71/283 (25%), Positives = 110/283 (38%), Gaps = 20/283 (7%)
Query: 39 DVHATVYRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVI-AGNAVVLRCVVPPHC 97
+ + VY+C R+ G A+S NI V + S W + + +G ++VL C P
Sbjct: 115 ETYEGVYQCTARNERG-AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGL 173
Query: 98 ADRISSTEWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRT 157
I W+ D+ L L+ G LY S V D ++C R T
Sbjct: 174 PPPIIF--WM-DNSFQRLPQSERVSQGLN-GDLYFSNVLPEDTREDYICYARFNHTQTIQ 229
Query: 158 AVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRV---GQDVRLPCAVHAWPVPTYRWFFEH 214
+ VI + P + + + G + L C P P W E
Sbjct: 230 QKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKE- 288
Query: 215 HEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPI 274
+ + P + T++K E L I V D+G + C N +G+ +H T+ V
Sbjct: 289 -DGMLP-KNRTVYKNF----EKTLQIIHVSEADSGNYQCIAKNALGA--IHHTISVRVKA 340
Query: 275 SVR--TKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE 315
+ T P+ L P D L C+ NG+P + WL NG +E
Sbjct: 341 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIE 383
Score = 35.9 bits (79), Expect = 0.23
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
++L+C G P ++YW L P R L I + + D G YQC A NA
Sbjct: 269 LSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNA 326
Score = 35.5 bits (78), Expect = 0.30
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 6/91 (6%)
Query: 269 IVTEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLE-PNERIEILEDG- 326
+V P + P+ P+ +I + C+ G P W NG + + + ++ G
Sbjct: 42 LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 327 --LRLHIKNTHKDD--QGIYQCFASNARDQA 353
L ++I + K + +G+YQC A N R A
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARNERGAA 132
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 57.6 bits (133), Expect = 6e-08
Identities = 44/171 (25%), Positives = 67/171 (39%), Gaps = 9/171 (5%)
Query: 186 RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETT----LWKRARLLDEGLLSIQ 241
+++ G+D ++ C PVP W + + +R L + G L
Sbjct: 27 KQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFN 86
Query: 242 KVRREDAGRFVCWLNNTVGSES--VHFTLIVTEPISVRTKPEVLRSKPKSDIALDCKVNG 299
KV + G + C+ NT+G + VH T+I P ++ R K LDC+V G
Sbjct: 87 KVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTG 146
Query: 300 HPIELVYWL--HNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
P ++WL N +R +G L I D G Y C A N
Sbjct: 147 DPKPKIFWLLPSNDMISFSIDRYTFHANG-SLTINKVKLLDSGEYVCVARN 196
Score = 54.0 bits (124), Expect = 8e-07
Identities = 76/316 (24%), Positives = 128/316 (40%), Gaps = 29/316 (9%)
Query: 45 YRCRMRSSVGYIAMSKNIHVYAALSSPWEVHVPDEYVIAGNAVVLRCVVPPHCADRISST 104
Y C ++++G M ++ V A + + ++ + AG+ VL C V D
Sbjct: 96 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEV---TGDPKPKI 152
Query: 105 EWLNDDDINVLHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVS 164
WL + +++ + +Y +GSL I+ V D ++C R+ +G T + L
Sbjct: 153 FWLLPSN-DMISFSIDRYTFHANGSLTINKVKLLD-SGEYVCVARNP-SGDDTKMYKL-- 207
Query: 165 HVIVTEPKGGVKPRVSVEQRSRRIRVGQDVR-----LPCAVHAWPVPTYRWFFEHHEQLT 219
+V++P P ++ SR + VR C P P W + LT
Sbjct: 208 -DVVSKP-----PLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLT 261
Query: 220 PIEETTLWKRARLLDEGLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPISVRT- 278
R + G L I+ VR D+ F+C N G + L V E + T
Sbjct: 262 ---APYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTF 318
Query: 279 -KP--EVLRSKPKSDIALDCKVNGH-PIELVYWLHNGRTLE--PNERIEILEDGLRLHIK 332
P E + ++ AL+C V+G+ P E+++ L NG P ++ I
Sbjct: 319 RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIIS 378
Query: 333 NTHKDDQGIYQCFASN 348
T ++D G Y+C A N
Sbjct: 379 KTTREDAGKYRCAARN 394
Score = 52.8 bits (121), Expect = 2e-06
Identities = 81/366 (22%), Positives = 137/366 (37%), Gaps = 37/366 (10%)
Query: 3 WLQSDNTPV-ASLSGLR-QILKNGSLEILPFTAELYRHDVHATVYRCRMRSSVGYIAMSK 60
W+ DN + A G R + KNG+LEI + + C R+ G +
Sbjct: 252 WIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLS------DSADFICVARNEGGESVLVV 305
Query: 61 NIHVYAALSSPWEVHVPDEYVIA--GNAVVLRCVVPPHCADRISSTEWLNDDDINVLHYL 118
+ V L P + +E ++A G + L C V + I W+ + +
Sbjct: 306 QLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEII---WILPNGTRFSNGP 362
Query: 119 GSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSH--VIVTEPKGGVK 176
S + + +I + +T + ++ C R+K+ I V + VI+T G VK
Sbjct: 363 QSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVK 422
Query: 177 PRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEG 236
+S G+ + L C P P +W ++ + + L D G
Sbjct: 423 G-IS----------GESLSLHCVSDGIPKPNIKWTMPSGYV---VDRPQINGKYILHDNG 468
Query: 237 LLSIQKVRREDAGRFVCWLNNTVGSESVHF-TLIVTEPISVRTKP-EVLRSKPKSDIALD 294
L I++ D G ++C N+VG + +IV P + +P + ++ + L
Sbjct: 469 TLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLH 528
Query: 295 CKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH------IKNTHKDDQGIYQCFASN 348
C G P + W +L E +LH I+N D GIY+C A N
Sbjct: 529 CVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKN 588
Query: 349 ARDQAY 354
Y
Sbjct: 589 PLGSDY 594
Score = 50.4 bits (115), Expect = 1e-05
Identities = 57/240 (23%), Positives = 102/240 (42%), Gaps = 29/240 (12%)
Query: 121 KYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGGVKPRVS 180
+Y ++G+LY + V ++ + + C ++ + V+ V +T PR+
Sbjct: 74 RYTLFNNGTLYFNKVGVAEEGD-YTCYAQNTLGKDEMKVHLTV----IT-----AAPRIR 123
Query: 181 VEQRS-RRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLT-PIEETTLWKRARLLDEGLL 238
++ +RI+ G L C V P P W ++ ++ I+ T G L
Sbjct: 124 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN------GSL 177
Query: 239 SIQKVRREDAGRFVCWLNNTVGSESVHFTL-IVTEPISVR---TKPEVLRSKP--KSDIA 292
+I KV+ D+G +VC N G ++ + L +V++P + T V+++ S
Sbjct: 178 TINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKH 237
Query: 293 LDCKVNGHPIELVYWL--HNGRTLEP--NERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
DC+ G P V W+ N P RI + ++G L I+N D + C A N
Sbjct: 238 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG-TLEIRNVRLSDSADFICVARN 296
>AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.
Length = 1264
Score = 57.6 bits (133), Expect = 6e-08
Identities = 56/236 (23%), Positives = 93/236 (39%), Gaps = 14/236 (5%)
Query: 115 LHYLGSKYHRLDDGSLYISAVSTSDRHNRFLCRVRDKITGIRTAVNTLVSHVIVTEPKGG 174
L + Y L G+L I VS D+ + + C + +T + V + ++V+ P
Sbjct: 161 LEHSTENYLILPSGNLQILNVSLEDKGS-YKCAAYNPVTH-QLKVEPIGRKLLVSRPSSD 218
Query: 175 -VKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLL 233
V ++ + V L C V P P W + + I + W+R
Sbjct: 219 DVHILHPTHSQALAVLSRSPVTLECVVSGVPAPQVYWLKDGQD----IAPGSNWRRLY-- 272
Query: 234 DEGLLSIQKVRREDAGRFVCWLNNTVGS-ESVHFTLIVTEPISVRTKPEVLRSKPKSDIA 292
L+ V D+G + C N G E V + + V E S+ + + +
Sbjct: 273 --SHLATDSVDPADSGNYSCMAGNKSGDVEYVTYMVNVLEHASISKGLQDQIVSLGATVH 330
Query: 293 LDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
C V+G+P W HN + + P+ R +GL+ I +D G+YQC A N
Sbjct: 331 FTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNGLK--ISGVTVEDVGMYQCVADN 384
Score = 42.3 bits (95), Expect = 0.003
Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 22/134 (16%)
Query: 170 EPKGGVKPRVSVEQRSRRIRVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKR 229
E GG KP + S ++ G V L C PVP RW ++ H +T L +
Sbjct: 398 ENDGGFKPVIITAPVSAKVADGDFVTLSCNASGLPVPVIRW-YDSHGLITSHPSQVLRSK 456
Query: 230 ARLLD----EGL----------------LSIQKVRREDAGRFVCWLNNTVGSESVHFTLI 269
+R EGL L IQ V +E AG+++C N G+ +L+
Sbjct: 457 SRKSQLSRPEGLNLEPVYFVLSQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLM 516
Query: 270 VTEPISVRTKPEVL 283
V P TK E +
Sbjct: 517 VV-PFETNTKAETV 529
Score = 40.3 bits (90), Expect = 0.010
Identities = 60/236 (25%), Positives = 98/236 (41%), Gaps = 39/236 (16%)
Query: 81 VIAGNAVVLRCVVPPHCADRISSTEWLND-DDINVLHYLGSKYHRLDDGSLYISAVSTSD 139
V++ + V L CVV A ++ WL D DI GS + RL L +V +D
Sbjct: 233 VLSRSPVTLECVVSGVPAPQVY---WLKDGQDIAP----GSNWRRLYS-HLATDSVDPAD 284
Query: 140 RHNRFLCRVRDKITGIR--TAVNTLVSHVIVTEPKGGVKPRVSVEQRSRRIRVGQDVRLP 197
N + C +K + T + ++ H +++ G++ ++ + +G V
Sbjct: 285 SGN-YSCMAGNKSGDVEYVTYMVNVLEHASISK---GLQDQI--------VSLGATVHFT 332
Query: 198 CAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGL-LSIQKVRREDAGRFVCWLN 256
C VH P P WF H+ Q PI + AR L G L I V ED G + C +
Sbjct: 333 CDVHGNPAPNCTWF--HNAQ--PIHPS-----ARHLTAGNGLKISGVTVEDVGMYQCVAD 383
Query: 257 NTVGSESVHFTLIVT-----EPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYW 307
N +G L + +P+ + T P + + L C +G P+ ++ W
Sbjct: 384 NGIGFMHSTGRLEIENDGGFKPVII-TAPVSAKVADGDFVTLSCNASGLPVPVIRW 438
Score = 38.7 bits (86), Expect = 0.032
Identities = 35/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Query: 233 LDEGLLSIQKVRREDAGRFVCWLNNTVG---SESVHFTLIVTEPISVRTKPEVLRSKPKS 289
+ +G L+I + G + C NN++G S ++ V TK V+ ++ KS
Sbjct: 77 IHQGTLTILSLNSSLLGYYQCLANNSIGAIVSGPATVSVAVLGDFGSSTK-HVITAEEKS 135
Query: 290 DIALDCKV-NGHPIELVYWLHNGRTLEPN-ERIEILEDGLRLHIKNTHKDDQGIYQCFAS 347
+ C+V +P V + G+ LE + E IL G L I N +D+G Y+C A
Sbjct: 136 AGFIGCRVPESNPKAEVRYKIRGKWLEHSTENYLILPSG-NLQILNVSLEDKGSYKCAAY 194
Query: 348 N 348
N
Sbjct: 195 N 195
Score = 35.1 bits (77), Expect = 0.39
Identities = 19/46 (41%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 305 VYWLHNGRTLEPN-ERIEILEDGLRLHIKNTHKDDQGIYQCFASNA 349
+ WLHNG+TL+ N E I+I + L I + + G YQC A+N+
Sbjct: 59 ISWLHNGKTLDGNLEHIKIHQG--TLTILSLNSSLLGYYQCLANNS 102
>BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth factor
receptor-like 1 protein.
Length = 504
Score = 57.2 bits (132), Expect = 9e-08
Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 177 PRVSVEQRSRRI-RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
P+++ + R++ R+G+ VRL C V P P W + + W R R+L +
Sbjct: 29 PKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSG------WSRFRVLPQ 82
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
GL +++V REDAG +VC N GS SV++TL+V + IS
Sbjct: 83 GL-KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDIS 121
Score = 45.6 bits (103), Expect = 3e-04
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPN-ERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C V G P L W +GRT+ R +L GL+ +K ++D G+Y C A+N
Sbjct: 47 VRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLK--VKQVEREDAGVYVCKATN 103
Score = 41.5 bits (93), Expect = 0.005
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 271 TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH 330
T+P +R + V+ S + L C +GHP + W+ + + L E E + L
Sbjct: 150 TQPSKMRRR--VIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLS 207
Query: 331 IKNTHKDDQGIYQCFASN 348
+KN +D G Y C SN
Sbjct: 208 LKNLRPEDSGKYTCRVSN 225
Score = 41.5 bits (93), Expect = 0.005
Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG VRL C P P W + + LT E K+ + LS++ +R ED+G
Sbjct: 164 VGSSVRLKCVASGHPRPDITWM-KDDQALTRPEAAEPRKK-----KWTLSLKNLRPEDSG 217
Query: 250 RFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
++ C ++N G+ + + + V ++P+ T P + CKV +
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPV 277
Query: 305 VYWL 308
+ WL
Sbjct: 278 IQWL 281
>AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein.
Length = 504
Score = 57.2 bits (132), Expect = 9e-08
Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 177 PRVSVEQRSRRI-RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
P+++ + R++ R+G+ VRL C V P P W + + W R R+L +
Sbjct: 29 PKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSG------WSRFRVLPQ 82
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
GL +++V REDAG +VC N GS SV++TL+V + IS
Sbjct: 83 GL-KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDIS 121
Score = 45.6 bits (103), Expect = 3e-04
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPN-ERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C V G P L W +GRT+ R +L GL+ +K ++D G+Y C A+N
Sbjct: 47 VRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLK--VKQVEREDAGVYVCKATN 103
Score = 41.5 bits (93), Expect = 0.005
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 271 TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH 330
T+P +R + V+ S + L C +GHP + W+ + + L E E + L
Sbjct: 150 TQPSKMRRR--VIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLS 207
Query: 331 IKNTHKDDQGIYQCFASN 348
+KN +D G Y C SN
Sbjct: 208 LKNLRPEDSGKYTCRVSN 225
Score = 41.5 bits (93), Expect = 0.005
Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG VRL C P P W + + LT E K+ + LS++ +R ED+G
Sbjct: 164 VGSSVRLKCVASGHPRPDITWM-KDDQALTRPEAAEPRKK-----KWTLSLKNLRPEDSG 217
Query: 250 RFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
++ C ++N G+ + + + V ++P+ T P + CKV +
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPV 277
Query: 305 VYWL 308
+ WL
Sbjct: 278 IQWL 281
>AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein.
Length = 504
Score = 57.2 bits (132), Expect = 9e-08
Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 177 PRVSVEQRSRRI-RVGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDE 235
P+++ + R++ R+G+ VRL C V P P W + + W R R+L +
Sbjct: 29 PKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSG------WSRFRVLPQ 82
Query: 236 GLLSIQKVRREDAGRFVCWLNNTVGSESVHFTLIVTEPIS 275
GL +++V REDAG +VC N GS SV++TL+V + IS
Sbjct: 83 GL-KVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDIS 121
Score = 45.6 bits (103), Expect = 3e-04
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 291 IALDCKVNGHPIELVYWLHNGRTLEPN-ERIEILEDGLRLHIKNTHKDDQGIYQCFASN 348
+ L C V G P L W +GRT+ R +L GL+ +K ++D G+Y C A+N
Sbjct: 47 VRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLK--VKQVEREDAGVYVCKATN 103
Score = 41.5 bits (93), Expect = 0.005
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 271 TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIELVYWLHNGRTLEPNERIEILEDGLRLH 330
T+P +R + V+ S + L C +GHP + W+ + + L E E + L
Sbjct: 150 TQPSKMRRR--VIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLS 207
Query: 331 IKNTHKDDQGIYQCFASN 348
+KN +D G Y C SN
Sbjct: 208 LKNLRPEDSGKYTCRVSN 225
Score = 41.5 bits (93), Expect = 0.005
Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 190 VGQDVRLPCAVHAWPVPTYRWFFEHHEQLTPIEETTLWKRARLLDEGLLSIQKVRREDAG 249
VG VRL C P P W + + LT E K+ + LS++ +R ED+G
Sbjct: 164 VGSSVRLKCVASGHPRPDITWM-KDDQALTRPEAAEPRKK-----KWTLSLKNLRPEDSG 217
Query: 250 RFVCWLNNTVGSESVHFTLIV-----TEPISVRTKPEVLRSKPKSDIALDCKVNGHPIEL 304
++ C ++N G+ + + + V ++P+ T P + CKV +
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPV 277
Query: 305 VYWL 308
+ WL
Sbjct: 278 IQWL 281
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.425
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 55,769,511
Number of Sequences: 224733
Number of extensions: 2369514
Number of successful extensions: 15489
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 331
Number of HSP's successfully gapped in prelim test: 794
Number of HSP's that attempted gapping in prelim test: 8471
Number of HSP's gapped (non-prelim): 4674
length of query: 366
length of database: 73,234,838
effective HSP length: 91
effective length of query: 275
effective length of database: 52,784,135
effective search space: 14515637125
effective search space used: 14515637125
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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