Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001887-TA|BGIBMGA001887-PA|IPR008672|Mitotic checkpoint
(621 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC009964-1|AAH09964.1| 718|Homo sapiens MAD1 mitotic arrest def... 91 8e-18
AF123318-1|AAD20359.1| 718|Homo sapiens mitotic checkpoint prot... 91 8e-18
AF083811-1|AAD24498.1| 718|Homo sapiens mitotic checkpoint prot... 90 2e-17
U33822-1|AAC52059.1| 803|Homo sapiens TXBP181 protein. 89 6e-17
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 77 1e-13
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 77 1e-13
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 77 1e-13
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 77 1e-13
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 73 3e-12
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 73 4e-12
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 73 4e-12
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 73 4e-12
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 73 4e-12
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 73 4e-12
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 73 4e-12
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 71 1e-11
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 68 9e-11
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 68 9e-11
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 68 9e-11
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 68 9e-11
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 68 9e-11
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 68 9e-11
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 67 2e-10
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 67 2e-10
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 67 2e-10
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 67 2e-10
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 67 2e-10
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 66 3e-10
AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen... 66 3e-10
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 66 5e-10
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 66 5e-10
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 65 6e-10
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 64 1e-09
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 64 1e-09
BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein. 64 1e-09
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 64 1e-09
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 64 1e-09
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 63 2e-09
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 63 2e-09
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 63 2e-09
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 63 2e-09
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 63 2e-09
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 63 2e-09
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 63 3e-09
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 62 4e-09
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 62 6e-09
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 62 6e-09
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 61 1e-08
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 60 2e-08
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 60 2e-08
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 60 2e-08
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 60 2e-08
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 59 4e-08
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 59 4e-08
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 59 4e-08
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 59 4e-08
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 59 4e-08
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 59 4e-08
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 59 4e-08
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 59 4e-08
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 59 4e-08
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 59 4e-08
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 59 4e-08
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 59 5e-08
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 59 5e-08
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 59 5e-08
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 58 7e-08
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 58 7e-08
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 58 7e-08
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 58 7e-08
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 58 9e-08
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 58 9e-08
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 58 9e-08
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 58 9e-08
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 58 9e-08
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 58 9e-08
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 58 9e-08
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 58 1e-07
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 58 1e-07
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 57 2e-07
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 57 2e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 57 2e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 57 2e-07
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 57 2e-07
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 56 3e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 56 3e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 56 3e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 56 3e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 56 3e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 56 3e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 56 3e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 56 3e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 56 3e-07
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 56 4e-07
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 56 4e-07
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 56 5e-07
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 56 5e-07
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 56 5e-07
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 56 5e-07
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 56 5e-07
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 55 7e-07
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 55 7e-07
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 55 7e-07
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 55 7e-07
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 55 7e-07
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 55 7e-07
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 55 9e-07
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 55 9e-07
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 55 9e-07
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 55 9e-07
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 55 9e-07
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 54 1e-06
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 54 1e-06
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 1e-06
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 1e-06
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 54 1e-06
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 54 1e-06
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 54 1e-06
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 54 2e-06
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 54 2e-06
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 54 2e-06
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 54 2e-06
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 54 2e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 54 2e-06
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 54 2e-06
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 54 2e-06
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 54 2e-06
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 54 2e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 54 2e-06
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 54 2e-06
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 54 2e-06
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 54 2e-06
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 53 3e-06
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 53 3e-06
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 53 3e-06
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 53 3e-06
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 53 3e-06
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 53 3e-06
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 53 3e-06
DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein. 53 3e-06
DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1 pro... 53 3e-06
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 53 3e-06
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 53 3e-06
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 53 3e-06
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 53 3e-06
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 53 3e-06
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 53 3e-06
BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein. 53 3e-06
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 53 3e-06
BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sp... 53 3e-06
AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sp... 53 3e-06
AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sp... 53 3e-06
AL445287-5|CAH71068.1| 765|Homo sapiens outer dense fiber of sp... 53 3e-06
AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of s... 53 3e-06
AL359091-22|CAI13505.1| 765|Homo sapiens outer dense fiber of s... 53 3e-06
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 53 3e-06
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 53 3e-06
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 53 3e-06
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 52 5e-06
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 5e-06
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 5e-06
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 52 5e-06
BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein. 52 5e-06
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 52 5e-06
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 52 6e-06
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 52 6e-06
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 52 6e-06
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 52 6e-06
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 52 6e-06
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 52 6e-06
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 52 6e-06
AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein. 52 6e-06
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 52 6e-06
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 52 6e-06
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 52 6e-06
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 52 6e-06
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 52 8e-06
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 52 8e-06
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 52 8e-06
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 52 8e-06
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 52 8e-06
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 52 8e-06
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 52 8e-06
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 52 8e-06
AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein. 52 8e-06
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 52 8e-06
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 52 8e-06
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 52 8e-06
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 52 8e-06
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 52 8e-06
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 51 1e-05
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 51 1e-05
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 51 1e-05
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 51 1e-05
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 51 1e-05
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 51 1e-05
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 51 1e-05
AY237537-1|AAP04414.1| 1335|Homo sapiens KIF27B protein. 51 1e-05
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 51 1e-05
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 51 1e-05
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 51 1e-05
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 51 1e-05
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 51 1e-05
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 51 1e-05
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 51 1e-05
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 51 1e-05
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 51 1e-05
AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein. 51 1e-05
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 51 1e-05
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 51 1e-05
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 51 1e-05
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 51 1e-05
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 51 1e-05
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 51 1e-05
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 51 1e-05
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 51 1e-05
BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein. 51 1e-05
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 51 1e-05
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 51 1e-05
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 51 1e-05
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 51 1e-05
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 51 1e-05
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 51 1e-05
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 51 1e-05
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 51 1e-05
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 51 1e-05
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 51 1e-05
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 51 1e-05
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 50 2e-05
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 50 2e-05
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 50 2e-05
BC047438-1|AAH47438.1| 354|Homo sapiens homer homolog 1 (Drosop... 50 2e-05
AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein. 50 2e-05
AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein. 50 2e-05
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 50 2e-05
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 50 2e-05
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 50 2e-05
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 50 2e-05
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 50 2e-05
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 50 2e-05
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 50 2e-05
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 50 2e-05
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 50 2e-05
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 50 2e-05
AB014555-1|BAA31630.1| 1083|Homo sapiens KIAA0655 protein protein. 50 2e-05
AB013384-1|BAA33713.1| 890|Homo sapiens HIP1R protein. 50 2e-05
BC132717-1|AAI32718.1| 1132|Homo sapiens phosphodiesterase 4D in... 50 3e-05
BC078660-1|AAH78660.1| 1132|Homo sapiens phosphodiesterase 4D in... 50 3e-05
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 50 3e-05
AY237536-1|AAP04413.1| 1401|Homo sapiens KIF27A protein. 50 3e-05
AY027796-1|AAK27377.1| 530|Homo sapiens ninein centrosomal prot... 50 3e-05
AY027795-1|AAK27376.1| 573|Homo sapiens ninein centrosomal prot... 50 3e-05
AY027794-1|AAK27375.1| 573|Homo sapiens ninein centrosomal prot... 50 3e-05
AL833273-1|CAD91152.1| 1509|Homo sapiens hypothetical protein pr... 50 3e-05
AL831815-1|CAD38529.1| 969|Homo sapiens hypothetical protein pr... 50 3e-05
AL354733-4|CAI16013.1| 1401|Homo sapiens kinesin family member 2... 50 3e-05
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AF186776-1|AAG17027.1| 573|Homo sapiens ninein centrosomal prot... 50 3e-05
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 50 3e-05
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 50 3e-05
AB046810-1|BAB13416.2| 1393|Homo sapiens KIAA1590 protein protein. 50 3e-05
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 50 3e-05
AB007946-1|BAA32322.2| 1148|Homo sapiens KIAA0477 protein protein. 50 3e-05
AB007923-1|BAA32299.2| 2296|Homo sapiens KIAA0454 protein protein. 50 3e-05
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 49 4e-05
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 49 4e-05
AY166853-1|AAO17292.1| 1317|Homo sapiens kinesin motor protein p... 49 4e-05
AL133654-1|CAB63770.1| 833|Homo sapiens hypothetical protein pr... 49 4e-05
AL118509-3|CAI43063.2| 1392|Homo sapiens chromosome 20 open read... 49 4e-05
AL118509-2|CAM28305.1| 1317|Homo sapiens chromosome 20 open read... 49 4e-05
AL117376-3|CAI43180.2| 1392|Homo sapiens chromosome 20 open read... 49 4e-05
AL117376-2|CAI43181.2| 1317|Homo sapiens chromosome 20 open read... 49 4e-05
AL049794-2|CAI22745.2| 1392|Homo sapiens chromosome 20 open read... 49 4e-05
AL049794-1|CAM28307.1| 1317|Homo sapiens chromosome 20 open read... 49 4e-05
Y17829-1|CAA76877.1| 354|Homo sapiens Syn47 protein protein. 49 6e-05
X63105-1|CAA44819.1| 726|Homo sapiens Tpr protein. 49 6e-05
BT009846-1|AAP88848.1| 354|Homo sapiens homer homolog 1 (Drosop... 49 6e-05
BC094764-1|AAH94764.1| 692|Homo sapiens TPR protein protein. 49 6e-05
BC016514-1|AAH16514.1| 687|Homo sapiens TPR protein protein. 49 6e-05
BC015502-1|AAH15502.1| 354|Homo sapiens homer homolog 1 (Drosop... 49 6e-05
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 49 6e-05
AY189940-1|AAO39000.1| 180|Homo sapiens HOMER1F protein. 49 6e-05
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 49 6e-05
AK223471-1|BAD97191.1| 354|Homo sapiens homer 1 variant protein. 49 6e-05
AK092201-1|BAC03827.1| 284|Homo sapiens protein ( Homo sapiens ... 49 6e-05
AF093262-1|AAC71026.1| 354|Homo sapiens homer-1b protein. 49 6e-05
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 48 7e-05
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 48 7e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 48 7e-05
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 48 7e-05
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 48 7e-05
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 48 7e-05
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 48 7e-05
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 48 7e-05
BC067085-1|AAH67085.1| 615|Homo sapiens HIP1R protein protein. 48 1e-04
AL832024-1|CAD89923.1| 988|Homo sapiens hypothetical protein pr... 48 1e-04
AL590452-8|CAH72528.1| 2240|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL590452-7|CAH72527.1| 988|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL590452-6|CAH72526.1| 969|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL590452-4|CAH72524.1| 2346|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL590452-3|CAH72523.1| 2362|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL590452-2|CAH72522.1| 1132|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-7|CAI22827.1| 2240|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-6|CAI22826.1| 988|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-5|CAI22825.1| 969|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-4|CAI22824.1| 2346|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-3|CAI22823.1| 2362|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL138796-2|CAI22822.1| 1132|Homo sapiens phosphodiesterase 4D in... 48 1e-04
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 48 1e-04
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 48 1e-04
AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protei... 48 1e-04
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 48 1e-04
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 48 1e-04
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 48 1e-04
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 48 1e-04
AB020671-1|BAA74887.2| 1402|Homo sapiens KIAA0864 protein protein. 48 1e-04
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 48 1e-04
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 48 1e-04
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 48 1e-04
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 48 1e-04
AK090414-1|BAC03395.1| 208|Homo sapiens FLJ00313 protein protein. 48 1e-04
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 48 1e-04
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 48 1e-04
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 47 2e-04
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 47 2e-04
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 47 2e-04
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 47 2e-04
AY319414-1|AAP83847.1| 657|Homo sapiens outer dense fiber of sp... 47 2e-04
AL445287-4|CAH71067.1| 638|Homo sapiens outer dense fiber of sp... 47 2e-04
AL445287-3|CAH71066.1| 701|Homo sapiens outer dense fiber of sp... 47 2e-04
AL359091-17|CAI13500.1| 638|Homo sapiens outer dense fiber of s... 47 2e-04
AL359091-16|CAI13499.1| 701|Homo sapiens outer dense fiber of s... 47 2e-04
AK025632-1|BAB15196.1| 720|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein. 47 2e-04
AF053970-1|AAC08409.1| 610|Homo sapiens outer dense fiber prote... 47 2e-04
AF012549-1|AAB66337.1| 638|Homo sapiens outer dense fiber prote... 47 2e-04
AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein. 47 2e-04
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 47 2e-04
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 47 2e-04
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 47 2e-04
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 47 2e-04
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 47 2e-04
BC078665-1|AAH78665.1| 775|Homo sapiens GRIP and coiled-coil do... 47 2e-04
BC057227-1|AAH57227.1| 318|Homo sapiens Unknown (protein for IM... 47 2e-04
BC014100-1|AAH14100.1| 775|Homo sapiens GRIP and coiled-coil do... 47 2e-04
AL357148-2|CAI16567.1| 1341|Homo sapiens breast cancer antigen N... 47 2e-04
AL357148-1|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 3... 47 2e-04
AL157387-4|CAH71319.1| 1460|Homo sapiens ankyrin repeat domain 3... 47 2e-04
AL157387-3|CAH71320.1| 1341|Homo sapiens breast cancer antigen N... 47 2e-04
AK000204-1|BAA91007.1| 782|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF525417-1|AAM91948.1| 775|Homo sapiens Golgi coiled coil prote... 47 2e-04
AF269087-1|AAK27325.1| 1341|Homo sapiens breast cancer antigen N... 47 2e-04
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 47 2e-04
AB112475-1|BAD05131.1| 782|Homo sapiens StAR protein binding pr... 47 2e-04
AB112474-1|BAD05130.1| 782|Homo sapiens StAR protein binding pr... 47 2e-04
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 47 2e-04
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 47 2e-04
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 46 3e-04
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 46 3e-04
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 46 3e-04
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 46 3e-04
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 46 3e-04
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 46 3e-04
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 46 3e-04
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 46 3e-04
AB202104-1|BAE78628.1| 756|Homo sapiens chromosome 6 open readi... 46 3e-04
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 46 4e-04
U79734-1|AAC51257.1| 914|Homo sapiens huntingtin interacting pr... 46 4e-04
L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human alternati... 46 4e-04
CR457227-1|CAG33508.1| 782|Homo sapiens C6orf18 protein. 46 4e-04
CR456763-1|CAG33044.1| 446|Homo sapiens NDP52 protein. 46 4e-04
BC139786-1|AAI39787.1| 517|Homo sapiens KRT74 protein protein. 46 4e-04
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 46 4e-04
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 46 4e-04
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 46 4e-04
BC110545-1|AAI10546.1| 1037|Homo sapiens huntingtin interacting ... 46 4e-04
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 46 4e-04
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 46 4e-04
BC066592-1|AAH66592.1| 1516|Homo sapiens CUTL1 protein protein. 46 4e-04
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 46 4e-04
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 46 4e-04
BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10 pro... 46 4e-04
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 46 4e-04
AL773544-6|CAI18483.1| 782|Homo sapiens chromosome 6 open readi... 46 4e-04
AL662844-15|CAM25639.1| 871|Homo sapiens coiled-coil alpha-heli... 46 4e-04
AL662844-10|CAI18328.1| 782|Homo sapiens coiled-coil alpha-heli... 46 4e-04
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement prot... 46 4e-04
AK000217-1|BAA91016.1| 782|Homo sapiens protein ( Homo sapiens ... 46 4e-04
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 46 4e-04
AF365404-1|AAL87037.1| 1030|Homo sapiens huntingtin-interacting ... 46 4e-04
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 46 4e-04
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 46 4e-04
AF052288-1|AAC33564.1| 995|Homo sapiens huntingtin interacting ... 46 4e-04
AC005086-1|AAP22331.1| 317|Homo sapiens unknown protein. 46 4e-04
AB103610-1|BAF31272.1| 756|Homo sapiens HCR protein protein. 46 4e-04
AB075522-1|BAE45765.1| 484|Homo sapiens putative protein produc... 46 4e-04
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 46 4e-04
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 46 5e-04
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 46 5e-04
BC000099-1|AAH00099.4| 655|Homo sapiens RRBP1 protein protein. 46 5e-04
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 46 5e-04
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 46 5e-04
AY590151-1|AAT01278.1| 534|Homo sapiens prostate cancer antigen... 46 5e-04
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 46 5e-04
AL137068-3|CAI12356.1| 828|Homo sapiens centrosomal protein 110... 46 5e-04
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 46 5e-04
AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protei... 46 5e-04
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 46 5e-04
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 46 5e-04
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 46 5e-04
AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein. 46 5e-04
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 46 5e-04
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 46 5e-04
Y09420-1|CAA70574.1| 400|Homo sapiens huntingtin interacting pr... 45 7e-04
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 45 7e-04
BC035913-1|AAH35913.1| 737|Homo sapiens PCNT protein protein. 45 7e-04
BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat con... 45 7e-04
BA000025-61|BAB63313.1| 756|Homo sapiens Tricohyalin homologue ... 45 7e-04
AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein. 45 7e-04
AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein. 45 7e-04
AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein. 45 7e-04
AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein. 45 7e-04
AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein. 45 7e-04
AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein. 45 7e-04
AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein. 45 7e-04
AL096710-2|CAI22043.1| 5457|Homo sapiens dystonin protein. 45 7e-04
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 45 7e-04
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 45 7e-04
AB088104-1|BAC54937.1| 756|Homo sapiens tricohyalin homologue p... 45 7e-04
AB029343-1|BAA82158.1| 756|Homo sapiens HCR protein. 45 7e-04
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 45 7e-04
U22897-1|AAA75297.1| 446|Homo sapiens NDP52 protein. 45 0.001
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 45 0.001
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 45 0.001
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 45 0.001
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 45 0.001
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 45 0.001
BC060826-1|AAH60826.1| 843|Homo sapiens GOLGA3 protein protein. 45 0.001
BC015893-1|AAH15893.1| 446|Homo sapiens calcium binding and coi... 45 0.001
BC004130-1|AAH04130.1| 446|Homo sapiens calcium binding and coi... 45 0.001
AL833308-1|CAD89924.1| 878|Homo sapiens hypothetical protein pr... 45 0.001
AK223227-1|BAD96947.1| 446|Homo sapiens nuclear domain 10 prote... 45 0.001
AK222666-1|BAD96386.1| 429|Homo sapiens nuclear domain 10 prote... 45 0.001
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 45 0.001
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 45 0.001
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 45 0.001
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 45 0.001
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 44 0.001
BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein. 44 0.001
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 44 0.001
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 44 0.001
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 44 0.001
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 44 0.001
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 44 0.001
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 44 0.001
AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110... 44 0.001
AK025336-1|BAB15114.1| 963|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK024004-1|BAB14769.1| 519|Homo sapiens protein ( Homo sapiens ... 44 0.001
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 44 0.001
AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein. 44 0.001
AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein. 44 0.001
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 44 0.001
AB014540-1|BAA31615.1| 603|Homo sapiens KIAA0640 protein protein. 44 0.001
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 44 0.002
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 44 0.002
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 44 0.002
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 44 0.002
AK000142-1|BAA90971.1| 752|Homo sapiens protein ( Homo sapiens ... 44 0.002
AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymph... 44 0.002
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 44 0.002
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 44 0.002
BC068997-1|AAH68997.1| 541|Homo sapiens centrosomal protein 63k... 44 0.002
BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain cont... 44 0.002
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 44 0.002
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 44 0.002
AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein. 44 0.002
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 44 0.002
AK056465-1|BAB71192.1| 703|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK023448-1|BAB14578.1| 541|Homo sapiens protein ( Homo sapiens ... 44 0.002
AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid anti... 44 0.002
Y00672-1|CAA68681.1| 142|Homo sapiens protein ( Human tpr mRNA ... 43 0.003
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 43 0.003
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 43 0.003
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 43 0.003
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 43 0.003
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 43 0.003
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 43 0.003
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 43 0.003
BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein. 43 0.003
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 43 0.003
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 43 0.003
BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein. 43 0.003
>BC009964-1|AAH09964.1| 718|Homo sapiens MAD1 mitotic arrest
deficient-like 1 (yeast) protein.
Length = 718
Score = 91.5 bits (217), Expect = 8e-18
Identities = 112/551 (20%), Positives = 227/551 (41%), Gaps = 42/551 (7%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
+ + I +K+ + ++E K ++ E ++ ++R+ ++
Sbjct: 54 RAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQL 113
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN---KDQISEM 212
+++ + ++ + N D K++ + +D L +A + K +ISE+
Sbjct: 114 QEREAGAEEKMQEQLERNRQCQQNLDAAS----KRLREKEDSLAQAGETINALKGRISEL 169
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+ + + ++ +SE + L+++L Q + ++ Q +L+ ++K+LE
Sbjct: 170 QWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
+ + K + L + LE+E+ +LR LR+ LL+E++ L +
Sbjct: 230 QKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRK 289
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXX 390
+ + +Q L +++ + ++L+SW + G + + L +
Sbjct: 290 LGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALK 349
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERD 450
L + L+ E + +G+L + R+ E+L RLQKR+LL+T+ERD
Sbjct: 350 DKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERD 409
Query: 451 SYRQQLDCYEKELT-------VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
R L Y+ ELT +T E V + + ++E L + +
Sbjct: 410 GMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQR 469
Query: 504 AHSKALE---------SLRNEVTRWREEAEGARRDVTKLRTQRD-------LLTASLERI 547
A +E S REEA+ R V +L +R +L A LER
Sbjct: 470 ADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
Query: 548 GPQ-------TKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALR--EGGAQADPEEL 598
Q TKVLH++ NP + A++++ ++ Q E ++L+ LR E G P +L
Sbjct: 530 ALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTV-PADL 588
Query: 599 QQMRQQLENSR 609
+ L +S+
Sbjct: 589 EAAAASLPSSK 599
>AF123318-1|AAD20359.1| 718|Homo sapiens mitotic checkpoint protein
protein.
Length = 718
Score = 91.5 bits (217), Expect = 8e-18
Identities = 112/551 (20%), Positives = 227/551 (41%), Gaps = 42/551 (7%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
+ + I +K+ + ++E K ++ E ++ ++R+ ++
Sbjct: 54 RAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQL 113
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN---KDQISEM 212
+++ + ++ + N D K++ + +D L +A + K +ISE+
Sbjct: 114 QEREAGAEEKMQEQLERNRQCQQNLDAAS----KRLREKEDSLAQAGETINALKGRISEL 169
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+ + + ++ +SE + L+++L Q + ++ Q +L+ ++K+LE
Sbjct: 170 QWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
+ + K + L + LE+E+ +LR LR+ LL+E++ L +
Sbjct: 230 QKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRK 289
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXX 390
+ + +Q L +++ + ++L+SW + G + + L +
Sbjct: 290 LGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALK 349
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERD 450
L + L+ E + +G+L + R+ E+L RLQKR+LL+T+ERD
Sbjct: 350 DKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERD 409
Query: 451 SYRQQLDCYEKELT-------VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
R L Y+ ELT +T E V + + ++E L + +
Sbjct: 410 GMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQR 469
Query: 504 AHSKALE---------SLRNEVTRWREEAEGARRDVTKLRTQRD-------LLTASLERI 547
A +E S REEA+ R V +L +R +L A LER
Sbjct: 470 ADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
Query: 548 GPQ-------TKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALR--EGGAQADPEEL 598
Q TKVLH++ NP + A++++ ++ Q E ++L+ LR E G P +L
Sbjct: 530 ALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTV-PADL 588
Query: 599 QQMRQQLENSR 609
+ L +S+
Sbjct: 589 EAAAASLPSSK 599
>AF083811-1|AAD24498.1| 718|Homo sapiens mitotic checkpoint protein
isoform MAD1a protein.
Length = 718
Score = 89.8 bits (213), Expect = 2e-17
Identities = 111/551 (20%), Positives = 227/551 (41%), Gaps = 42/551 (7%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
+ + I +K+ + ++E K ++ E ++ ++R+ ++
Sbjct: 54 RAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQL 113
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN---KDQISEM 212
+++ + ++ + N D K++ + +D L +A + K +ISE+
Sbjct: 114 QEREAGAEEKMQEQLERNRQCQQNLDAAS----KRLREKEDSLAQAGETINALKGRISEL 169
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+ + + ++ +SE + ++++L Q + ++ Q +L+ ++K+LE
Sbjct: 170 QWSVMDQEMRVKRLESEKQDVQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
+ + K + L + LE+E+ +LR LR+ LL+E++ L +
Sbjct: 230 QKLSLQEQDAAIVKNMKSELVRLPRLERELEQLREESAHLREMRETNGLLQEELEGLQRK 289
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXX 390
+ + +Q L +++ + ++L+SW + G + + L +
Sbjct: 290 LGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALK 349
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERD 450
L + L+ E + +G+L + R+ E+L RLQKR+LL+T+ERD
Sbjct: 350 DKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERD 409
Query: 451 SYRQQLDCYEKELT-------VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
R L Y+ ELT +T E V + + ++E L + +
Sbjct: 410 GMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQR 469
Query: 504 AHSKALE---------SLRNEVTRWREEAEGARRDVTKLRTQRD-------LLTASLERI 547
A +E S REEA+ R V +L +R +L A LER
Sbjct: 470 ADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
Query: 548 GPQ-------TKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALR--EGGAQADPEEL 598
Q TKVLH++ NP + A++++ ++ Q E ++L+ LR E G P +L
Sbjct: 530 ALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTV-PADL 588
Query: 599 QQMRQQLENSR 609
+ L +S+
Sbjct: 589 EAAAASLPSSK 599
>U33822-1|AAC52059.1| 803|Homo sapiens TXBP181 protein.
Length = 803
Score = 88.6 bits (210), Expect = 6e-17
Identities = 112/551 (20%), Positives = 229/551 (41%), Gaps = 43/551 (7%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
+ + I +K+ + ++E K ++ E ++ ++R+ ++
Sbjct: 54 RAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQL 113
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN---KDQISEM 212
+++ + ++ + N D K++ + +D L +A + K +ISE+
Sbjct: 114 QEREAGAEEKMQEQLERNRQCQQNLDAAS----KRLREKEDSLAQAGETINALKGRISEL 169
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+ + + ++ +SE + ++++L Q + ++ Q +L+ ++K+LE
Sbjct: 170 QWSVMDQEMRVKRLESEKQDVQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLE 229
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
+ + K + L + LE+E+ +LR E +LR+ LL+E++ L +
Sbjct: 230 QKLSLQEQDAAIVKNMKSELVRLPRLERELEQLR-EESALREMRETNGLLQEELEGLQRK 288
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXX 390
+ + +Q L +++ + ++L+SW + G + + L +
Sbjct: 289 LGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALK 348
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERD 450
L + L+ E + +G+L + R+ E+L RLQKR+LL+T+ERD
Sbjct: 349 DKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERD 408
Query: 451 SYRQQLDCYEKELT-------VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
R L Y+ ELT +T E V + + ++E L + +
Sbjct: 409 GMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQR 468
Query: 504 AHSKALE---------SLRNEVTRWREEAEGARRDVTKLRTQRD-------LLTASLERI 547
A +E S REEA+ R V +L +R +L A LER
Sbjct: 469 ADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 528
Query: 548 GPQ-------TKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALR--EGGAQADPEEL 598
Q TKVLH++ NP + A++++ ++ Q E ++L+ LR E G P +L
Sbjct: 529 ALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTV-PADL 587
Query: 599 QQMRQQLENSR 609
+ L +S+
Sbjct: 588 EAAAASLPSSK 598
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 77.4 bits (182), Expect = 1e-13
Identities = 105/499 (21%), Positives = 203/499 (40%), Gaps = 27/499 (5%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
+S N + +K Q+L EE+ S +RD RA ++ + ++
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAEAEAREKETKALSLARALEEAMEQK 1492
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---DQISEMKKDMDELLQALEGA 226
A E + L + E DL D+ + E S + Q+ EMK ++EL L+
Sbjct: 1493 A-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA- 1550
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + ++ +
Sbjct: 1551 -TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 287 TAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
A+K+L ++ +LE + N + +++ + +++ + +L + + + +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 345 EAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXX 401
E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEIANSSGKGALALEEKR--- 1725
Query: 402 HLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQQLDC 458
L +A L+ E ++ G + K I ++ L L ++ ++ RQQL+
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 459 YEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHSKALE 510
KEL V L EG S+ L A++ QLE+ L + A K L+
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+ +V R AE + K T+ L LE + + + + + ++
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Query: 571 ELEAAQEEIKKLKVALREG 589
+A E+ LK LR G
Sbjct: 1906 TADAMNREVSSLKNKLRRG 1924
Score = 58.0 bits (134), Expect = 9e-08
Identities = 114/555 (20%), Positives = 215/555 (38%), Gaps = 44/555 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM-------QILFEEEKASLIEQHKRDER 143
E KR K++ AQ+ +L+ + N +R E+ Q+ + L + + +
Sbjct: 1244 EHKRKKVE-----AQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL--LEA 201
D ++E LK D EK +Q+ + ++ LE
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED-EKNSFREQLEEEEEAKHNLEK 1357
Query: 202 NVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
++ Q+++MKK M++ + LE A+ L+K+L + R E+ ++LEK
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417
Query: 261 FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
QQ +L +L + D + + QK+ + EK ++ A ER +A +
Sbjct: 1418 LQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE- 1473
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKL-SSVESQLESWMSAARA-HGVE-SAGALRD 377
E + L +E + EL + + +E + S ++ H +E S AL
Sbjct: 1474 -KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERD------KATGKLNDLTTVRK 429
+E L + +K +ERD ++ K L +
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEK 488
E+ + +K+ + R L E + + +E + L A+++ +
Sbjct: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 489 SL---QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
L + R+ I A + K L+S+ E+ + +EE A R + + +RD L +
Sbjct: 1653 ELDDTRASREEILA-QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 546 RIGPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR 602
+ L L EA+ Q+ +ELE Q + + L++ Q D +L R
Sbjct: 1712 NSSGK-GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 603 ---QQLENSRIKLKR 614
Q+ EN+R +L+R
Sbjct: 1771 SHAQKNENARQQLER 1785
Score = 54.0 bits (124), Expect = 2e-06
Identities = 84/371 (22%), Positives = 161/371 (43%), Gaps = 35/371 (9%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 364 ---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ V + L+ E + + E L E +K+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS--- 1015
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVAL 478
L ++ E++I L++RL R + RQ+L+ ++L T ++ A A
Sbjct: 1016 -KSLAKLKNKHEAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKL 533
++ QL K + + +A + A K AL+ +R ++++ +E+ E R K
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
Q+ L LE + +T++ ++ AA+ + + +E +E+ LK L E A+
Sbjct: 1131 EKQKRDLGEELEAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKT 1182
Query: 594 DPEELQQMRQQ 604
++Q+MRQ+
Sbjct: 1183 HEAQIQEMRQK 1193
Score = 48.0 bits (109), Expect = 1e-04
Identities = 101/491 (20%), Positives = 202/491 (41%), Gaps = 41/491 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 1209
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
+ +L A K LE + +L + V+ L + +++ K VE+QL+ +
Sbjct: 1210 RVKANLEKA---KQTLENERGELANEVKVLLQGK---GDSEHKRKKVEAQLQE-LQVKFN 1262
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
G L D + LT++ + L+ + L +
Sbjct: 1263 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE--- 1319
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLD-------CYEKELT-----VTLCGEEGAG 474
+N++ L L +L V E++S+R+QL+ EK++ V ++
Sbjct: 1320 --ENRQKL--SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHS-KALESLRNEVTRWREEAEGARRDVTKL 533
SV L +++++ LQ +DL H A + L TR ++E + D+
Sbjct: 1376 SVGCLET-AEEVKRKLQ--KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQ 1432
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
R L ++ Q T + A A+++ E EA ++E K L +A A
Sbjct: 1433 RQSACNLEKKQKKF-DQLLAEEKTIS-AKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 594 DPEELQQMRQQ 604
EL+++ +Q
Sbjct: 1491 QKAELERLNKQ 1501
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 77.4 bits (182), Expect = 1e-13
Identities = 105/499 (21%), Positives = 203/499 (40%), Gaps = 27/499 (5%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
+S N + +K Q+L EE+ S +RD RA ++ + ++
Sbjct: 721 QSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAEAEAREKETKALSLARALEEAMEQK 779
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---DQISEMKKDMDELLQALEGA 226
A E + L + E DL D+ + E S + Q+ EMK ++EL L+
Sbjct: 780 A-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA- 837
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + ++ +
Sbjct: 838 -TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 896
Query: 287 TAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
A+K+L ++ +LE + N + +++ + +++ + +L + + + +
Sbjct: 897 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 956
Query: 345 EAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXX 401
E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 957 ENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEIANSSGKGALALEEKR--- 1012
Query: 402 HLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQQLDC 458
L +A L+ E ++ G + K I ++ L L ++ ++ RQQL+
Sbjct: 1013 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLER 1072
Query: 459 YEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHSKALE 510
KEL V L EG S+ L A++ QLE+ L + A K L+
Sbjct: 1073 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1132
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+ +V R AE + K T+ L LE + + + + + ++
Sbjct: 1133 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1192
Query: 571 ELEAAQEEIKKLKVALREG 589
+A E+ LK LR G
Sbjct: 1193 TADAMNREVSSLKNKLRRG 1211
Score = 58.4 bits (135), Expect = 7e-08
Identities = 114/556 (20%), Positives = 216/556 (38%), Gaps = 45/556 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM-------QILFEEEKASLIEQHKRDER 143
E KR K++ AQ+ +L+ + N +R E+ Q+ + L + + +
Sbjct: 530 EHKRKKVE-----AQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 584
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL---LE 200
D ++E LK D EK +Q+ + +++ LE
Sbjct: 585 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED-EKNSFREQLEEEEEEAKHNLE 643
Query: 201 ANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
++ Q+++MKK M++ + LE A+ L+K+L + R E+ ++LEK
Sbjct: 644 KQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKT 703
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
QQ +L +L + D + + QK+ + EK ++ A ER +A +
Sbjct: 704 RLQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 760
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKL-SSVESQLESWMSAARA-HGVE-SAGALR 376
E + L +E + EL + + +E + S ++ H +E S AL
Sbjct: 761 --KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 818
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERD------KATGKLNDLTTVR 428
+E L + +K +ERD ++ K L
Sbjct: 819 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 878
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLCGEEGAGSVALLSARVQQLE 487
+ E+ + +K+ + R L E + + +E + L A+++
Sbjct: 879 REMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 938
Query: 488 KSL---QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
+ L + R+ I A + K L+S+ E+ + +EE A R + + +RD L +
Sbjct: 939 RELDDTRASREEILA-QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 997
Query: 545 ERIGPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQM 601
+ L L EA+ Q+ +ELE Q + + L++ Q D +L
Sbjct: 998 ANSSGK-GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLE 1056
Query: 602 R---QQLENSRIKLKR 614
R Q+ EN+R +L+R
Sbjct: 1057 RGHAQKNENARQQLER 1072
Score = 53.2 bits (122), Expect = 3e-06
Identities = 85/360 (23%), Positives = 153/360 (42%), Gaps = 32/360 (8%)
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI-CN 318
E + V + K+L E + QS+ ++L +L+ E T L A LR +
Sbjct: 137 EEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAE-TELCAEAEELRARLTAK 195
Query: 319 KLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA---ARAHGVES 371
K LEE H L +RV E Q +Q E + + + +E QLE SA + V +
Sbjct: 196 KQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT 255
Query: 372 AGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQ 431
L+ E + + E L E +K+ L ++
Sbjct: 256 EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS----KSLAKLKNKH 311
Query: 432 ESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVALLSARVQQLEKS 489
E++I L++RL R + RQ+L+ ++L T ++ A A ++ QL K
Sbjct: 312 EAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 367
Query: 490 LQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
+ + +A + A K AL+ +R ++++ +E+ E R K Q+ L L
Sbjct: 368 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 427
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
E + +T++ ++ AA+ + + +E +E+ LK L E A+ ++Q+MRQ+
Sbjct: 428 EAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKTHEAQIQEMRQK 479
Score = 49.2 bits (112), Expect = 4e-05
Identities = 85/414 (20%), Positives = 172/414 (41%), Gaps = 30/414 (7%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 318 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 377
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 378 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 437
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 438 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 495
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
+ +L A K LE + +L + V+ L +++ K VE+QL+ +
Sbjct: 496 RVKANLEKA---KQTLENERGELANEVKVLLQGG---RDSEHKRKKVEAQLQE-LQVKFN 548
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
G L D + LT++ + L+ + L +
Sbjct: 549 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE--- 605
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
+N++ L L +L V E++S+R+QL+ E+E L +A L A+V +
Sbjct: 606 --ENRQKL--SLSTKLKQVEDEKNSFREQLEEEEEEAKHNL-----EKQIATLHAQVADM 656
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREE-AEGARRDVTKLRTQRDL 539
+K ++ + + K + L R E+ A + + TK R Q++L
Sbjct: 657 KKKMEDSVGCLETAE-EVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 709
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 77.4 bits (182), Expect = 1e-13
Identities = 105/499 (21%), Positives = 203/499 (40%), Gaps = 27/499 (5%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
+S N + +K Q+L EE+ S +RD RA ++ + ++
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAEAEAREKETKALSLARALEEAMEQK 1492
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---DQISEMKKDMDELLQALEGA 226
A E + L + E DL D+ + E S + Q+ EMK ++EL L+
Sbjct: 1493 A-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA- 1550
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + ++ +
Sbjct: 1551 -TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 287 TAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
A+K+L ++ +LE + N + +++ + +++ + +L + + + +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 345 EAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXX 401
E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEIANSSGKGALALEEKR--- 1725
Query: 402 HLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQQLDC 458
L +A L+ E ++ G + K I ++ L L ++ ++ RQQL+
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 459 YEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHSKALE 510
KEL V L EG S+ L A++ QLE+ L + A K L+
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+ +V R AE + K T+ L LE + + + + + ++
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Query: 571 ELEAAQEEIKKLKVALREG 589
+A E+ LK LR G
Sbjct: 1906 TADAMNREVSSLKNKLRRG 1924
Score = 58.0 bits (134), Expect = 9e-08
Identities = 114/555 (20%), Positives = 215/555 (38%), Gaps = 44/555 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM-------QILFEEEKASLIEQHKRDER 143
E KR K++ AQ+ +L+ + N +R E+ Q+ + L + + +
Sbjct: 1244 EHKRKKVE-----AQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL--LEA 201
D ++E LK D EK +Q+ + ++ LE
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED-EKNSFREQLEEEEEAKHNLEK 1357
Query: 202 NVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
++ Q+++MKK M++ + LE A+ L+K+L + R E+ ++LEK
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417
Query: 261 FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
QQ +L +L + D + + QK+ + EK ++ A ER +A +
Sbjct: 1418 LQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE- 1473
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKL-SSVESQLESWMSAARA-HGVE-SAGALRD 377
E + L +E + EL + + +E + S ++ H +E S AL
Sbjct: 1474 -KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERD------KATGKLNDLTTVRK 429
+E L + +K +ERD ++ K L +
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEK 488
E+ + +K+ + R L E + + +E + L A+++ +
Sbjct: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 489 SL---QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
L + R+ I A + K L+S+ E+ + +EE A R + + +RD L +
Sbjct: 1653 ELDDTRASREEILA-QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 546 RIGPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR 602
+ L L EA+ Q+ +ELE Q + + L++ Q D +L R
Sbjct: 1712 NSSGK-GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 603 ---QQLENSRIKLKR 614
Q+ EN+R +L+R
Sbjct: 1771 SHAQKNENARQQLER 1785
Score = 54.0 bits (124), Expect = 2e-06
Identities = 84/371 (22%), Positives = 161/371 (43%), Gaps = 35/371 (9%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 364 ---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ V + L+ E + + E L E +K+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS--- 1015
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVAL 478
L ++ E++I L++RL R + RQ+L+ ++L T ++ A A
Sbjct: 1016 -KSLAKLKNKHEAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKL 533
++ QL K + + +A + A K AL+ +R ++++ +E+ E R K
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
Q+ L LE + +T++ ++ AA+ + + +E +E+ LK L E A+
Sbjct: 1131 EKQKRDLGEELEAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKT 1182
Query: 594 DPEELQQMRQQ 604
++Q+MRQ+
Sbjct: 1183 HEAQIQEMRQK 1193
Score = 48.0 bits (109), Expect = 1e-04
Identities = 101/491 (20%), Positives = 202/491 (41%), Gaps = 41/491 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 1209
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
+ +L A K LE + +L + V+ L + +++ K VE+QL+ +
Sbjct: 1210 RVKANLEKA---KQTLENERGELANEVKVLLQGK---GDSEHKRKKVEAQLQE-LQVKFN 1262
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
G L D + LT++ + L+ + L +
Sbjct: 1263 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE--- 1319
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLD-------CYEKELT-----VTLCGEEGAG 474
+N++ L L +L V E++S+R+QL+ EK++ V ++
Sbjct: 1320 --ENRQKL--SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHS-KALESLRNEVTRWREEAEGARRDVTKL 533
SV L +++++ LQ +DL H A + L TR ++E + D+
Sbjct: 1376 SVGCLET-AEEVKRKLQ--KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQ 1432
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
R L ++ Q T + A A+++ E EA ++E K L +A A
Sbjct: 1433 RQSACNLEKKQKKF-DQLLAEEKTIS-AKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 594 DPEELQQMRQQ 604
EL+++ +Q
Sbjct: 1491 QKAELERLNKQ 1501
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 77.4 bits (182), Expect = 1e-13
Identities = 105/499 (21%), Positives = 203/499 (40%), Gaps = 27/499 (5%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
+S N + +K Q+L EE+ S +RD RA ++ + ++
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAEAEAREKETKALSLARALEEAMEQK 1492
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---DQISEMKKDMDELLQALEGA 226
A E + L + E DL D+ + E S + Q+ EMK ++EL L+
Sbjct: 1493 A-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA- 1550
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + ++ +
Sbjct: 1551 -TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 287 TAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
A+K+L ++ +LE + N + +++ + +++ + +L + + + +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 345 EAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXX 401
E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEIANSSGKGALALEEKR--- 1725
Query: 402 HLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQQLDC 458
L +A L+ E ++ G + K I ++ L L ++ ++ RQQL+
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 459 YEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHSKALE 510
KEL V L EG S+ L A++ QLE+ L + A K L+
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1845
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+ +V R AE + K T+ L LE + + + + + ++
Sbjct: 1846 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATE 1905
Query: 571 ELEAAQEEIKKLKVALREG 589
+A E+ LK LR G
Sbjct: 1906 TADAMNREVSSLKNKLRRG 1924
Score = 58.0 bits (134), Expect = 9e-08
Identities = 114/555 (20%), Positives = 215/555 (38%), Gaps = 44/555 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM-------QILFEEEKASLIEQHKRDER 143
E KR K++ AQ+ +L+ + N +R E+ Q+ + L + + +
Sbjct: 1244 EHKRKKVE-----AQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSK 1298
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL--LEA 201
D ++E LK D EK +Q+ + ++ LE
Sbjct: 1299 LTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED-EKNSFREQLEEEEEAKHNLEK 1357
Query: 202 NVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
++ Q+++MKK M++ + LE A+ L+K+L + R E+ ++LEK
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTR 1417
Query: 261 FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
QQ +L +L + D + + QK+ + EK ++ A ER +A +
Sbjct: 1418 LQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE- 1473
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKL-SSVESQLESWMSAARA-HGVE-SAGALRD 377
E + L +E + EL + + +E + S ++ H +E S AL
Sbjct: 1474 -KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERD------KATGKLNDLTTVRK 429
+E L + +K +ERD ++ K L +
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEK 488
E+ + +K+ + R L E + + +E + L A+++ +
Sbjct: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 489 SL---QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
L + R+ I A + K L+S+ E+ + +EE A R + + +RD L +
Sbjct: 1653 ELDDTRASREEILA-QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 546 RIGPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR 602
+ L L EA+ Q+ +ELE Q + + L++ Q D +L R
Sbjct: 1712 NSSGK-GALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 603 ---QQLENSRIKLKR 614
Q+ EN+R +L+R
Sbjct: 1771 SHAQKNENARQQLER 1785
Score = 54.0 bits (124), Expect = 2e-06
Identities = 84/371 (22%), Positives = 161/371 (43%), Gaps = 35/371 (9%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 364 ---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ V + L+ E + + E L E +K+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS--- 1015
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVAL 478
L ++ E++I L++RL R + RQ+L+ ++L T ++ A A
Sbjct: 1016 -KSLAKLKNKHEAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKL 533
++ QL K + + +A + A K AL+ +R ++++ +E+ E R K
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
Q+ L LE + +T++ ++ AA+ + + +E +E+ LK L E A+
Sbjct: 1131 EKQKRDLGEELEAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKT 1182
Query: 594 DPEELQQMRQQ 604
++Q+MRQ+
Sbjct: 1183 HEAQIQEMRQK 1193
Score = 48.0 bits (109), Expect = 1e-04
Identities = 101/491 (20%), Positives = 202/491 (41%), Gaps = 41/491 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 1209
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
+ +L A K LE + +L + V+ L + +++ K VE+QL+ +
Sbjct: 1210 RVKANLEKA---KQTLENERGELANEVKVLLQGK---GDSEHKRKKVEAQLQE-LQVKFN 1262
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
G L D + LT++ + L+ + L +
Sbjct: 1263 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE--- 1319
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLD-------CYEKELT-----VTLCGEEGAG 474
+N++ L L +L V E++S+R+QL+ EK++ V ++
Sbjct: 1320 --ENRQKL--SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHS-KALESLRNEVTRWREEAEGARRDVTKL 533
SV L +++++ LQ +DL H A + L TR ++E + D+
Sbjct: 1376 SVGCLET-AEEVKRKLQ--KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQ 1432
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
R L ++ Q T + A A+++ E EA ++E K L +A A
Sbjct: 1433 RQSACNLEKKQKKF-DQLLAEEKTIS-AKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 594 DPEELQQMRQQ 604
EL+++ +Q
Sbjct: 1491 QKAELERLNKQ 1501
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 72.9 bits (171), Expect = 3e-12
Identities = 135/624 (21%), Positives = 259/624 (41%), Gaps = 51/624 (8%)
Query: 23 TEPPKDKLSASTNL-NFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKRLRRDSSGN 81
T+ K+K + + N S+ +++E +S L K K S+ T D + N
Sbjct: 966 TKVEKEKHATENKVKNLSEEMTALEENISKLT---KEKKSLQEAHQQTLDDLQVEEDKVN 1022
Query: 82 GTTAPPSPWE--TKRLKIDLIAAK---AQITKLESRVNHQHTIRKEMQILFEEEKASLIE 136
G + E T L+ L K A + + + ++ + +E + E EK + E
Sbjct: 1023 GLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEE 1082
Query: 137 QHKRDERAVSDME----DXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKTD 186
+ K+ E +S ++ D K+ E + L+A +K+++D
Sbjct: 1083 KLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKK---DMDELLQALEGAQSEVEMLKKELVKQTSR 243
L +++ ++ ++L EA+ + QI KK + ++ + LE A + E L K+ +
Sbjct: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK--Q 1200
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD---SYKDWQTQSKTAQKRLCNMAELEK 300
A+ +L Q++ Q++ + EL+ E D S + ++SK+ +R C E +
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 301 EVTRLRANERS--LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV----KLSSVE 354
+ + +++ + D K L+ Q +L+ RVE + + +L ++K +L ++
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 355 SQLESWMSA--ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY 412
Q+E A A AH ++S+ D L + T KY
Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKT-KY 1379
Query: 413 ERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY---RQQLDCYEKELTVTLCG 469
E D A + +L +K + +++ + S +Q+L ++L L
Sbjct: 1380 ETD-AIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDL-- 1436
Query: 470 EEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALESLRNEVTRWREEAEGAR 527
E + A L + + +K L ++ + + + A K SL E+ + R E
Sbjct: 1437 ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVV 1496
Query: 528 RDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALR 587
+ LR + L E I T+ + T EA+K +K+L ++E L+VAL
Sbjct: 1497 DQLETLRRENKNLQ---EEISDLTEQIAETGKNLQEAEK--TKKL--VEQEKSDLQVALE 1549
Query: 588 EGGAQADPEELQQMRQQLENSRIK 611
E + EE + +R QLE S++K
Sbjct: 1550 EVEGSLEHEESKILRVQLELSQVK 1573
Score = 44.8 bits (101), Expect = 0.001
Identities = 101/526 (19%), Positives = 207/526 (39%), Gaps = 41/526 (7%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDM 148
PW KI + A+ K + + KE E + L E+ + +D+
Sbjct: 832 PWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDL 891
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
+ ++ K L+A KE T+ ++ ++ +L+ + +D+
Sbjct: 892 QLQVQSETENLMDAEERCEGLIKSKILLEAKV-KELTERLEEEEEMNSELVAKKRNLEDK 950
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
S +K+D+D+L L + E + + VK S E+ T L+ + K +T +
Sbjct: 951 CSSLKRDIDDLELTLTKVEKEKHATENK-VKNLS--EEMTALEENISK-------LTKEK 1000
Query: 269 KEL-EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLR-DAICNKLLLE 323
K L E + + D Q + + A+LE++ L + E+ LR D K LE
Sbjct: 1001 KSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD---ALE 380
+ + L+ + ++ E K SQL++ + + H ++ +++ +E
Sbjct: 1061 GDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIE 1120
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L E+ + ++A+G + + K +E+ ++++
Sbjct: 1121 ELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRR 1180
Query: 441 RLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAH 500
L T + ++ L + + +V GE+ + L Q+LEK + +
Sbjct: 1181 DLEEATLQHEATAATLRKKQAD-SVAELGEQ----IDNLQRVKQKLEKEKSELK--MEID 1233
Query: 501 DPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNP 560
D ++ +AL ++ + R RT D + + QT+++H N
Sbjct: 1234 DMASNIEALSKSKSNIER-------------TCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280
Query: 561 AAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
A Q Q + EL EE + L L + QA ++L+++++Q+E
Sbjct: 1281 KARLQTQ-NGELSHRVEEKESLISQLTK-SKQALTQQLEELKRQME 1324
Score = 44.4 bits (100), Expect = 0.001
Identities = 94/479 (19%), Positives = 201/479 (41%), Gaps = 33/479 (6%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEE---EKASLIEQHKRDERAVSDMEDXX 152
K+D A+ + + ESR + M+ +EE + +L ++K + +SD+ +
Sbjct: 1463 KLDESQAELEAAQKESRSLSTELFK--MRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDL-HKQIADLKDKLLEANVSNKDQISE 211
+ +E DL+ ++ + L H++ L+ +L + V ++
Sbjct: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKV 1580
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKE 270
++KD +E+ Q +Q E L+ L + +LK ++E E + Q+ ++
Sbjct: 1581 IEKD-EEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQ 1639
Query: 271 LEYERDSYKDWQTQSKTAQKRLCNM----AELEKEVTRL-RANERSLRDAICNKLLLE-- 323
+ + + Q Q K +Q L + +L++++ + R N L + K+ LE
Sbjct: 1640 MAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQT 1699
Query: 324 EQVHQLTSR--VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALE- 380
E+ +L+ + ++A VQL LH L + + +LE+ ++ +A S R+A E
Sbjct: 1700 ERTRRLSEQELLDASDRVQL-LHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEK 1758
Query: 381 --SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR-KNQESLIHR 437
A+ HL L+ +L++ + K + I +
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 438 LQKRLLLVTRERDSYRQQ-------LDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEKS 489
L+ R+ + E D +++ YE+++ +T EE ++ L V +L+
Sbjct: 1819 LENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAK 1878
Query: 490 LQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASLE 545
++ Y+ + A+++ +++E+ E A+ A V KLR + RD+ + +E
Sbjct: 1879 VKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKME 1937
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 820 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 874
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 875 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 932
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 933 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 992
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 993 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1051
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1052 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1111
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1112 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1171
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1172 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1229
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1230 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1273
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 262 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 321
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 322 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 373
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 374 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 428
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 429 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 483
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 484 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 540
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 541 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 592
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 593 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 640
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 641 LEVMRQELQVAQRKLQ 656
Score = 43.6 bits (98), Expect = 0.002
Identities = 70/322 (21%), Positives = 135/322 (41%), Gaps = 19/322 (5%)
Query: 297 ELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ 356
ELE +T+LRA E SL+D++ L E + Q +++ L + +L E K L + Q
Sbjct: 22 ELELSMTKLRAEEASLQDSLSKLSALNESLAQ--DKLD-LNRLVAQLEEEKSALQGRQRQ 78
Query: 357 LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
E + AR E LR LE + L +++ TL++ER +
Sbjct: 79 AEQEATVAREE-QERLEELR--LEQEVARQGLEGSLRVAEQAQEA-LEQQLPTLRHERSQ 134
Query: 417 ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE---LTVTLCGEEGA 473
+L L+ +E + + ++ + ++ + KE L V L E
Sbjct: 135 LQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAERE 194
Query: 474 GSVALLSARVQQLEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT- 531
G A +LEK +L+G + + LE+ R ++ + A+ +T
Sbjct: 195 GRTLSEEATRLRLEKEALEG-----SLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG 249
Query: 532 KLRTQRDLLTASLERIGPQTKVL-HLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+L R + A+ E+ +++ EAQ + ++ A +E++++L+ +E
Sbjct: 250 ELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQ-REKEAA 308
Query: 591 AQADPEELQQMRQQLENSRIKL 612
+ E Q++ QL+ + +L
Sbjct: 309 WRELEAERAQLQSQLQREQEEL 330
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 816 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 862
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 863 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 922
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 923 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 978
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 979 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1031
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1032 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1085
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1086 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1145
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1146 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1183
Score = 36.7 bits (81), Expect = 0.24
Identities = 44/216 (20%), Positives = 94/216 (43%), Gaps = 17/216 (7%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1085 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1144
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1145 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1202
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1203 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1262
Query: 349 KLSSVESQLESWMSA-ARAHGVESAGALRDALESAL 383
+L S ++Q E + A RAH + L+ L+ L
Sbjct: 1263 RLRSAQAQTERTLEARERAHR-QRVSTLKGQLQQEL 1297
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 1398 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 1452
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 1453 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 1510
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 1511 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 1570
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 1571 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1629
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1630 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1689
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1690 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1749
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1750 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1807
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1808 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1851
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 433 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 488
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 489 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 546
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 547 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 605
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 606 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 661
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 662 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 721
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 722 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 781
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 782 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 841
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 842 KASLDKELMAQKLVQAEREAQASLREQ 868
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 840 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 899
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 900 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 951
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 952 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 1006
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 1007 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1061
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 1062 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 1118
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 1119 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 1170
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 1171 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 1218
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 1219 LEVMRQELQVAQRKLQ 1234
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 1394 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 1440
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 1441 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 1500
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 1501 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 1556
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 1557 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1609
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1610 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1663
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1664 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1723
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1724 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1761
Score = 36.3 bits (80), Expect = 0.32
Identities = 41/200 (20%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1663 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1722
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1723 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1780
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1781 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1840
Query: 349 KLSSVESQLESWMSA-ARAH 367
+L S ++Q E + A RAH
Sbjct: 1841 RLRSAQAQTERTLEARERAH 1860
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 1517 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 1571
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 1572 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 1629
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 1630 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 1689
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 1690 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1748
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1749 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1808
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1809 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1869 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1926
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1927 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1970
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 552 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 607
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 665
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 666 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 724
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 725 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 840
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 841 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 900
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 901 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 960
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 961 KASLDKELMAQKLVQAEREAQASLREQ 987
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 959 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 1019 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 1070
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 1071 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 1125
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 1126 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1180
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 1181 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 1237
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 1238 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 1289
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 1290 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 1337
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 1338 LEVMRQELQVAQRKLQ 1353
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 1513 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 1559
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 1560 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 1619
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 1620 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 1675
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 1676 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1728
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1729 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1782
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1783 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1842
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1843 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1880
Score = 36.3 bits (80), Expect = 0.32
Identities = 41/200 (20%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1782 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1841
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1842 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1899
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1900 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1959
Query: 349 KLSSVESQLESWMSA-ARAH 367
+L S ++Q E + A RAH
Sbjct: 1960 RLRSAQAQTERTLEARERAH 1979
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 1398 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 1452
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 1453 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 1510
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 1511 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 1570
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 1571 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1629
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1630 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1689
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1690 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1749
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1750 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1807
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1808 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1851
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 433 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 488
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 489 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 546
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 547 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 605
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 606 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 661
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 662 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 721
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 722 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 781
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 782 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 841
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 842 KASLDKELMAQKLVQAEREAQASLREQ 868
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 840 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 899
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 900 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 951
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 952 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 1006
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 1007 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1061
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 1062 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 1118
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 1119 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 1170
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 1171 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 1218
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 1219 LEVMRQELQVAQRKLQ 1234
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 1394 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 1440
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 1441 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 1500
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 1501 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 1556
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 1557 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1609
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1610 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1663
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1664 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1723
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1724 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1761
Score = 36.3 bits (80), Expect = 0.32
Identities = 41/200 (20%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1663 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1722
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1723 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1780
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1781 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1840
Query: 349 KLSSVESQLESWMSA-ARAH 367
+L S ++Q E + A RAH
Sbjct: 1841 RLRSAQAQTERTLEARERAH 1860
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 1517 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 1571
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 1572 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 1629
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 1630 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 1689
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 1690 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1748
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1749 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1808
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1809 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1869 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1926
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1927 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1970
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 552 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 607
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 665
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 666 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 724
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 725 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 781 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 840
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 841 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 900
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 901 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 960
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 961 KASLDKELMAQKLVQAEREAQASLREQ 987
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 959 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 1019 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 1070
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 1071 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 1125
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 1126 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1180
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 1181 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 1237
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 1238 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 1289
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 1290 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 1337
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 1338 LEVMRQELQVAQRKLQ 1353
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 1513 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 1559
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 1560 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 1619
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 1620 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 1675
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 1676 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1728
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1729 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1782
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1783 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1842
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1843 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1880
Score = 36.3 bits (80), Expect = 0.32
Identities = 41/200 (20%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1782 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1841
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1842 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1899
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1900 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1959
Query: 349 KLSSVESQLESWMSA-ARAH 367
+L S ++Q E + A RAH
Sbjct: 1960 RLRSAQAQTERTLEARERAH 1979
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 72.5 bits (170), Expect = 4e-12
Identities = 100/464 (21%), Positives = 206/464 (44%), Gaps = 24/464 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E +A +E +L+ + + L++Q+A+++ + ++ S Q+ + + +E ++++
Sbjct: 1419 ELRSAQRERDELRT----QTSALNRQLAEMEAER-DSATSRARQLQKAVAESEEARRSVD 1473
Query: 225 GAQSEVEM---LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
G S V+ L++E V+++ R + T +Q+ Q S+L+ + + K
Sbjct: 1474 GRLSGVQAELALQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKAN 1531
Query: 282 QTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPV 339
+T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +
Sbjct: 1532 ETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL 1591
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q ++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 1592 QRQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK 1650
Query: 400 XXHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSY 452
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 1651 NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1710
Query: 453 RQQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
QL + L GE A +V L + L++ L + +A + +
Sbjct: 1711 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1770
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
LR E R + + KLR+ D + S E+ G + L AEAQ+QI ++
Sbjct: 1771 LRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQ 1828
Query: 572 LEAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LEA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 1829 LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 1872
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 454 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 509
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 510 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 567
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 568 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 626
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 627 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 682
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 683 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 742
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 743 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 802
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 803 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 862
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 863 KASLDKELMAQKLVQAEREAQASLREQ 889
Score = 44.8 bits (101), Expect = 0.001
Identities = 100/436 (22%), Positives = 187/436 (42%), Gaps = 45/436 (10%)
Query: 182 KEKTDLHKQIADLK--DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+EK L K++ K EA S ++Q + ++D+ L + E A E+E + +L
Sbjct: 861 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 920
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q R ++ +L +LE E ++++ ++ L+ ERD + +++ +++ ++ E E
Sbjct: 921 QLQREQE--ELLARLEA---EKEELSEEIAALQQERD---EGLLLAESEKQQALSLKESE 972
Query: 300 KEVTRLRANERSLRDAICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
K T L R ++ L +E Q SR E + ++ +L + +Q E
Sbjct: 973 K--TALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRST---VNALTSELRDLRAQRE 1027
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKA 417
AA AH E A + LG L E+ L+ E +A
Sbjct: 1028 ---EAAAAHAQEVRRLQEQARD--LGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEA 1082
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
KL + R+ Q L++ L +ER++ R+ E+ + E S+
Sbjct: 1083 QRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRS---NEELRSAVKKAESERISLK 1139
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + +Q L+ R + + L + EV R R E ARR++ +LR Q
Sbjct: 1140 LANEDKEQKLALLEEARTAVG-----KEAGELRTGLQEVERSRLE---ARRELQELRRQM 1191
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE 597
+L + R+G + AE Q +++ E A++E ++ + LR+ + +
Sbjct: 1192 KMLDSENTRLGRE----------LAELQGRLALG-ERAEKESRRETLGLRQRLLKGE-AS 1239
Query: 598 LQQMRQQLENSRIKLK 613
L+ MRQ+L+ ++ KL+
Sbjct: 1240 LEVMRQELQVAQRKLQ 1255
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/400 (21%), Positives = 156/400 (39%), Gaps = 35/400 (8%)
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
E LQ L AQ E + EL QTS L QL + E TS+ ++L+ +
Sbjct: 1415 EFLQELRSAQRE----RDELRTQTSA------LNRQLAEMEAERDSATSRARQLQ---KA 1461
Query: 278 YKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + ++ RL + AEL + +R +ER R + LE + S + A
Sbjct: 1462 VAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRAS 1521
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
Q ++ + KL + +L+ + A+ + V+ R +LE G
Sbjct: 1522 QEKISKMKANETKLEGDKRRLKEVLDASESRTVK-LELQRRSLE---GELQRSRLGLSDR 1577
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
L + V +L+ + + K L + + RL L V + R ++
Sbjct: 1578 EAQAQALQDRVDSLQRQVADSEVKAGTL-------QLTVERLNGALAKVEESEGALRDKV 1630
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG--YRDLIAAHDPHAHSKALESLRN 514
+ LT L + + S+ + L+K+L + + A +AL R
Sbjct: 1631 ----RGLTEALA--QSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARK 1684
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + E+ + R +V L QR L+++ + A +++ E
Sbjct: 1685 QSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRL 1744
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
QE + L+ AL + +A+ E+++ +LE R+ L+R
Sbjct: 1745 LQERLGSLQRALAQ--LEAEKREVERSALRLEKDRVALRR 1782
Score = 36.3 bits (80), Expect = 0.32
Identities = 41/200 (20%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 1684 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 1743
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 1744 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 1801
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 1802 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 1861
Query: 349 KLSSVESQLESWMSA-ARAH 367
+L S ++Q E + A RAH
Sbjct: 1862 RLRSAQAQTERTLEARERAH 1881
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 70.9 bits (166), Expect = 1e-11
Identities = 91/443 (20%), Positives = 184/443 (41%), Gaps = 26/443 (5%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
K E K+ + + K D+ K + +L+ ++ + + Q+ EMK ++EL
Sbjct: 95 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELE----KSKRALEQQVEEMKTQLEELEDE 150
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L+ +E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + +
Sbjct: 151 LQA--TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 208
Query: 283 TQSKTAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ + A+K+L ++ +LE + N + +++ + +++ + +L + + +
Sbjct: 209 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL 268
Query: 341 LELHEAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXX 397
+ E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 269 AQAKENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEI---ANSSGKGALAL 324
Query: 398 XXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQ 454
L +A L+ E ++ G + K I ++ L L ++ ++ RQ
Sbjct: 325 EEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQ 384
Query: 455 QLDCYEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHS 506
QL+ KEL V L EG S+ L A++ QLE+ L + A
Sbjct: 385 QLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTE 444
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
K L+ + +V R AE + K T+ L LE + + + + +
Sbjct: 445 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 504
Query: 567 QISKELEAAQEEIKKLKVALREG 589
++ +A E+ LK LR G
Sbjct: 505 DATETADAMNREVSSLKNKLRRG 527
Score = 41.9 bits (94), Expect = 0.006
Identities = 57/260 (21%), Positives = 114/260 (43%), Gaps = 21/260 (8%)
Query: 131 KASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQ 190
+ ++ Q K +E+ + ME + A +E +L D+ K
Sbjct: 264 REEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELA---DEIANSSGKG 320
Query: 191 IADLKDKL-LEANVSNKDQISEMKKDMDELLQ-ALEGAQSEVEMLKKELVKQTSRAEQCT 248
L++K LEA ++ ++ E ++ EL+ L+ A +++ + +L + S A++
Sbjct: 321 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 380
Query: 249 QLKNQLEKQNFEFQQVTSKLKELE-YERDSYKDWQT--QSKTAQ--KRLCN-MAELEKEV 302
+ QLE+QN +++ KL+E+E + YK T ++K AQ ++L N E +
Sbjct: 381 NARQQLERQN---KELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAAC 437
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
++R E+ L+D + L ++++ + L + K +L E + +
Sbjct: 438 KQVRRTEKKLKDVL---LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ---- 490
Query: 363 AARAHGVESAGALRDALESA 382
A A + L DA E+A
Sbjct: 491 RANASRRKLQRELEDATETA 510
Score = 34.3 bits (75), Expect = 1.3
Identities = 42/210 (20%), Positives = 89/210 (42%), Gaps = 14/210 (6%)
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E+ A L+ + ++ DL + + + +H L+K + ++ + + QL+ E EL
Sbjct: 93 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 152
Query: 465 VTLCGEEGAGSVAL-LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
T E+ + + L A Q E+ LQG D + K + +R +V E
Sbjct: 153 AT---EDAKLRLEVNLQAMKAQFERDLQG-------RDEQSEEKKKQLVR-QVREMEAEL 201
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
E R+ + R L L+ + + + A + +++ +++ E+ +
Sbjct: 202 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTR 261
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLK 613
+ E AQA +E ++ + +E I+L+
Sbjct: 262 ASREEILAQA--KENEKKLKSMEAEMIQLQ 289
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 68.1 bits (159), Expect = 9e-11
Identities = 110/511 (21%), Positives = 214/511 (41%), Gaps = 64/511 (12%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+L+S +N H+ E + E L EQ + + D E +++
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIA---DLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
+L+ DK K +Q A KL EA ++ +Q+ D D+ +Q LE
Sbjct: 471 EKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQ-NDLEQVLRQIGDKDQKIQNLE 529
Query: 225 G----AQSEVEMLKKE---LVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERD 276
++ + +L+KE L + E T + NQL+++N Q QVT ++L+ + +
Sbjct: 530 ALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSE 589
Query: 277 SYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
S+K Q L +V +A+ R+ +D + L LE V++L S
Sbjct: 590 SHKQAQ-------------ENLHDQVQEQKAHLRAAQDRV---LSLETSVNELNS----- 628
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L+E+K K+S ++ Q++ A+ + SA A + A + L
Sbjct: 629 -----QLNESKEKVSQLDIQIK-----AKTELLLSAEAAKTAQRADL------QNHLDTA 672
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
+E+ + + D+ T KL D ES + +++ L + ++ + Q+
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 457 DCYEKE-LTVTLCGEEGAGSVAL-------LSARVQQLEKSLQGYRDLIAAH--DPHAHS 506
E + L V E+ + L R +L K L+ ++++++ D S
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-ERIGPQTKVLHLTNNPAAEAQ 565
+ALES++ ++T+ EE + ++D L + + L RI QT V L +
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRI--QTTVTEL--QKVKMEK 848
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPE 596
+ + EL ++++ K+ +L+ ++ + E
Sbjct: 849 EALMTELSTVKDKLSKVSDSLKNSKSEFEKE 879
Score = 55.6 bits (128), Expect = 5e-07
Identities = 86/476 (18%), Positives = 185/476 (38%), Gaps = 22/476 (4%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX---XXXXXXXXXKD 164
KL + + ++++ + L +E K E + R + V++++ KD
Sbjct: 801 KLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD 860
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
+ + + K+ K+ ++KE I DL+ E + Q+ K+ EL ++LE
Sbjct: 861 KLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLE 920
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+ LK EL S EQ Q +N L++ E QQ+ + EL+ + K Q +
Sbjct: 921 KEKEASHQLKLEL---NSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK-QIE 976
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEEQVHQLTSRVEALQP--- 338
+ + ++ + + E E + ++ ++ K +L+ + + LQ
Sbjct: 977 ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFY 1036
Query: 339 -VQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGALRDALESALGXXXXXXXXXXX 395
+ EL + L SVE +L + + + + L L++A
Sbjct: 1037 GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ 1096
Query: 396 XXXXXXHLTEEVATLKYERDK----ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
+++ K ++K KL ++ ++ QE I +L + L + + +S
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE--LKSHKLES 1154
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
++ + + + + E G L A V+Q +++ Q +D + + + +E
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEK 1214
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
+ +E+ G ++ +TA E +G K + +E +KQ
Sbjct: 1215 EAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/532 (16%), Positives = 204/532 (38%), Gaps = 27/532 (5%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
+++ + + +L S++N ++ I + + L+ +D+++
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 159 XXXXKDEFNTAAKEHKDLKANW-DKEK--TDLHKQIADLKDKLLEANVSNKDQISEMKKD 215
+ E N + + A DK++ + L + + K+K L ++ ++KK
Sbjct: 676 LQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 216 MDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYER 275
+ L+ + ++ L+++ T + T+L QLE + L++
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 276 DSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+S K T+ + ++ L E + T+++ E + R ++ V +L
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR--------IQTTVTELQKVKME 847
Query: 336 LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD------ALESALGXXXXX 389
+ + EL K KLS V L++ S + A+ D L+ L
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMEN 907
Query: 390 XXXXXXXXXXXXHLTEEVA-TLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+E + LK E + +L K E +LQ + + +
Sbjct: 908 TLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQS 967
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHAHS 506
+ ++Q++ + EL + + + + L ++ Q + L ++ I+ ++
Sbjct: 968 SEQKKKQIEALQGELKIAVLQKTELEN--KLQQQLTQAAQELAAEKEKISVLQNNYEKSQ 1025
Query: 507 KALESLRNEVTRWREEAEGARRDV----TKLRTQRDLLTASLERIGPQTKVLHLTNNPAA 562
+ + L+++ E R+D+ KL ++ L ++ +IG Q K++ A
Sbjct: 1026 ETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
++ +K+ + QE K L+ +E + + E + + + E IK ++
Sbjct: 1086 TLEQDSAKKEQQLQERCKALQDIQKEKSLK-EKELVNEKSKLAEIEEIKCRQ 1136
Score = 45.2 bits (102), Expect = 7e-04
Identities = 44/237 (18%), Positives = 109/237 (45%), Gaps = 11/237 (4%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQ-HKRDERAVSDME 149
+ + L+ +L A Q T+LE+++ Q T + ++ E+EK S+++ +++ + ++
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQLT-QAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ + + ++ + + + + Q L +L A + +
Sbjct: 1033 SDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQ-NKLIQELKTAKATLEQDS 1091
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++ ++ + E +AL+ Q E + +KELV + S+ + ++K + EK E ++ +LK
Sbjct: 1092 AKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEK---EITKLNEELK 1148
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
++ +S K+ Q + EL+ + L+A ++ N+ +L++QV
Sbjct: 1149 --SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKA---AVEQEKRNQQILKDQV 1200
Score = 36.3 bits (80), Expect = 0.32
Identities = 51/260 (19%), Positives = 109/260 (41%), Gaps = 18/260 (6%)
Query: 121 KEMQILFEEEKASLIEQHK-RDERAVS----DMEDXXXXXXXXXXXXKDEFNTAAKEHKD 175
KE +++ E+ K + IE+ K R E+ ++ +++ KD ++ +
Sbjct: 1115 KEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLE 1174
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LK 234
L+ D K + ++ + ++L+ V +++ E+KK+ E L E E+ +K
Sbjct: 1175 LQGKADSLKAAVEQEKRN--QQILKDQVKKEEE--ELKKEFIEKEAKLHSEIKEKEVGMK 1230
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLC 293
K + Q T L L E+Q ++ ELE + D + + T Q
Sbjct: 1231 KHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQN--- 1287
Query: 294 NMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVK 349
N E + R E + L L+ ++ T+ V+ L Q +Q++ +A +
Sbjct: 1288 NQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNR 1347
Query: 350 LSSVESQLESWMSAARAHGV 369
+ ++++++ M+ + V
Sbjct: 1348 KWAEDNEVQNCMACGKGFSV 1367
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 68.1 bits (159), Expect = 9e-11
Identities = 122/584 (20%), Positives = 241/584 (41%), Gaps = 54/584 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 276 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 333
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 334 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 387
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 388 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 443
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 444 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 500
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 501 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 558
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 559 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 618
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 619 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 675
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 676 EQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 735
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 736 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 795
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ +RI + L + A E+ + + +E+ A + ++++
Sbjct: 796 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 839
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 62 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 114
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 115 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 172
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 173 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 219
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 220 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 272
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 273 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 331
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 332 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 389
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 390 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 448
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 449 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 508
Query: 574 AAQEEIK 580
+ E++
Sbjct: 509 EYETELE 515
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 68.1 bits (159), Expect = 9e-11
Identities = 122/584 (20%), Positives = 241/584 (41%), Gaps = 54/584 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1374 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1431
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1485
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1486 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1541
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1598
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1599 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1716
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1717 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ +RI + L + A E+ + + +E+ A + ++++
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1937
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1213
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1214 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1274 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1333
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1334 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1386
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1387 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1445
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1506 KEELERTNKMLK 1517
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 905
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 906 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 959
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 960 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 1073
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1133
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1134 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1186
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1187 KKALDE-ETRSHEAQVQEMRQK 1207
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1160 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1212
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1213 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1270
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1271 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1318 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1370
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1371 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1429
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1487
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1488 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1607 EYETELE 1613
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 950 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1008
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 1009 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1068
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 1069 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1128
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1129 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1188
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1305
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1306 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1364 EAKQNLERH 1372
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 857 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 912
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 913 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 964
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 965 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 1019
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 1020 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 1069
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1123
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1124 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1183
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1184 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1231
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 68.1 bits (159), Expect = 9e-11
Identities = 122/584 (20%), Positives = 241/584 (41%), Gaps = 54/584 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 17 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 74
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 75 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 128
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 129 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 184
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 185 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 241
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 242 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRK 299
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 300 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 359
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 360 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 416
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 417 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 476
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 477 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 536
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ +RI + L + A E+ + + +E+ A + ++++
Sbjct: 537 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 580
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 68.1 bits (159), Expect = 9e-11
Identities = 122/584 (20%), Positives = 241/584 (41%), Gaps = 54/584 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1252 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1309
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1310 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1363
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1364 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1419
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1420 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1476
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1477 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1534
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1535 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1594
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1595 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1651
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1652 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1711
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1712 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1771
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ +RI + L + A E+ + + +E+ A + ++++
Sbjct: 1772 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1815
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 852 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 911
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 912 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 971
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 972 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1031
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1032 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1091
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1092 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1151
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1152 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1211
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1212 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1264
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1265 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1323
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1324 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1383
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1384 KEELERTNKMLK 1395
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 727 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 783
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 784 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 837
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 838 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 895
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 896 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 951
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 952 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1011
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1012 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1064
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1065 KKALDE-ETRSHEAQVQEMRQK 1085
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1038 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1090
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1091 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1148
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1149 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1195
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1196 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1248
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1249 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1307
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1308 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1365
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1366 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1424
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1425 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1484
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1485 EYETELE 1491
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 772 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 827
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 828 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 886
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 887 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 946
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 947 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1006
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1007 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1066
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1067 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1124
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1125 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1183
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1184 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1241
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1242 EAKQNLERH 1250
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 735 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 790
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 791 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 842
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 843 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 897
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 898 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 947
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 948 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1001
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1002 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1061
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1062 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1109
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 68.1 bits (159), Expect = 9e-11
Identities = 122/584 (20%), Positives = 241/584 (41%), Gaps = 54/584 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1379 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1436
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1437 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1490
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1491 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1546
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1547 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1603
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1604 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1661
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1662 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1721
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1722 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1778
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1779 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1838
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1839 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1898
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ +RI + L + A E+ + + +E+ A + ++++
Sbjct: 1899 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1942
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 979 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1038
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 1039 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1098
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 1099 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1158
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1159 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1218
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1219 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1278
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1279 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1338
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1339 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1391
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1392 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1450
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1451 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1510
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1511 KEELERTNKMLK 1522
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 854 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 910
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 911 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 964
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 965 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1022
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 1023 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 1078
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 1079 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1138
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1139 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1191
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1192 KKALDE-ETRSHEAQVQEMRQK 1212
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1165 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1217
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1218 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1275
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1276 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1322
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1323 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1375
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1376 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1434
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1435 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1492
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1493 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1551
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1552 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1611
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1612 EYETELE 1618
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 899 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 954
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 955 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1013
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 1014 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1073
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 1074 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1133
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1134 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1193
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1194 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1251
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1252 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1310
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1311 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1368
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1369 EAKQNLERH 1377
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 862 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 917
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 918 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 969
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 970 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 1024
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 1025 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 1074
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 1075 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1128
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1129 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1188
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1189 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1236
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 67.3 bits (157), Expect = 2e-10
Identities = 122/583 (20%), Positives = 241/583 (41%), Gaps = 54/583 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 481 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 538
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 539 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 592
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 593 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 648
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 649 RALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 705
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + ++ + + A+K+L ++ +LE + + ++ E +++
Sbjct: 706 --RQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 763
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 764 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 823
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 824 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 880
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 881 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 940
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 941 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1000
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
+ +RI + L + A E+ + + +E+ A + +++
Sbjct: 1001 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1043
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 81 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 140
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 141 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 200
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 201 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 260
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 261 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 320
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 321 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 380
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 381 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 440
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 441 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 493
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 494 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 552
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 553 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 612
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 613 KEELERTNKMLK 624
Score = 55.2 bits (127), Expect = 7e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 267 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 319
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 320 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 377
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 378 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 424
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 425 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 477
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 478 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 536
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 537 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 594
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 595 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 653
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 654 QMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 713
Query: 574 AAQEEIK 580
+ E++
Sbjct: 714 EYETELE 720
Score = 50.0 bits (114), Expect = 2e-05
Identities = 99/477 (20%), Positives = 200/477 (41%), Gaps = 55/477 (11%)
Query: 184 KTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
+T+L+ + +++ +L + K ++ E+ +M+ L+ E +++ +K++ +Q
Sbjct: 13 ETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 68
Query: 244 AEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQSKTAQKRL----C 293
E+ + + + +Q + ++VT +K+K+LE E D + K ++R+
Sbjct: 69 LEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 127
Query: 294 NMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV------------EALQP 338
N+AE E K +T+L+ S+ + +L EE+ Q ++ E +
Sbjct: 128 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 187
Query: 339 VQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALESALGXXXXXXXX 392
+Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 188 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 247
Query: 393 XXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS- 451
L EE+ LK E + +R +E + L+K L TR ++
Sbjct: 248 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 307
Query: 452 ---YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGYRDLI--AAHDPH 503
RQ+ +ELT L E+ + A L Q LEK L G ++ A +
Sbjct: 308 VQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 365
Query: 504 AHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERIGPQTKVLHLTNN 559
K LE+ E+ + E AR + V KL+ + + +T L + K + L +
Sbjct: 366 HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE--AEGKAIKLAKD 423
Query: 560 PAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLENSRIKLKRY 615
A Q+ E QEE + KL V+ + + + LQ + ++ L+R+
Sbjct: 424 -VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 479
Score = 50.0 bits (114), Expect = 2e-05
Identities = 96/459 (20%), Positives = 187/459 (40%), Gaps = 33/459 (7%)
Query: 181 DKEKTDLHKQIADLKD--KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKEL 237
++E+ L Q+ + + + LE ++S + Q+S+ KK + + +E + + +KE+
Sbjct: 456 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 515
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
T + E+ ++LEK QQ +L +L + D+ + + + Q++ +
Sbjct: 516 ENLTQQYEEKAAAYDKLEKTKNRLQQ---ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 572
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
EK ++ A+ER +A + E + L +E + EL L + L
Sbjct: 573 EEKNISSKYADERDRAEAEARE--KETKALSLARALEEALEAKEELERTNKMLKAEMEDL 630
Query: 358 ESWMS--AARAHGVE-SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--Y 412
S H +E S AL +E L + LK +
Sbjct: 631 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQF 690
Query: 413 ERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER---DSYRQQLDCYEKELTV--- 465
ERD +A + N+ R+ + +H + L ER + +++L+ K+L +
Sbjct: 691 ERDLQARDEQNE--EKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQAD 748
Query: 466 -TLCG-EEGAGSVALLSARVQQLEKSLQ---GYRDLIAAHDPHAHSKALESLRNEVTRWR 520
+ G EE + L A+++ ++ L+ RD I A KA +SL ++ + +
Sbjct: 749 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA-KSLEADLMQLQ 807
Query: 521 EEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
E+ A R + +++ L L L Q+ +ELE Q ++
Sbjct: 808 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 867
Query: 581 KLKVALREGGAQAD--PEELQQMR---QQLENSRIKLKR 614
+ +R+ QA+ EL R Q+ E++R +L+R
Sbjct: 868 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 906
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 67.3 bits (157), Expect = 2e-10
Identities = 122/583 (20%), Positives = 240/583 (41%), Gaps = 54/583 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1367 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1424
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1478
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1479 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1534
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1591
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1592 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1709
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1710 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
+ +RI + L + A E+ + + +E+ A + +++
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1206
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1267 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1326
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1327 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1379
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1438
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1499 KEELERTNKMLK 1510
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 898
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 899 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 1066
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1126
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1127 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1179
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1180 KKALDE-ETRSHEAQVQEMRQK 1200
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1153 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1205
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1206 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1263
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1264 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1311 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1363
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1364 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1422
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1480
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1481 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1600 EYETELE 1606
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 942
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 943 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1001
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 1002 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1061
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 1062 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1121
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1122 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1298
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1299 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1357 EAKQNLERH 1365
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/457 (20%), Positives = 180/457 (39%), Gaps = 29/457 (6%)
Query: 181 DKEKTDLHKQIADLKD--KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKEL 237
++E+ L Q+ + + + LE ++S + Q+S+ KK + + +E + + +KE+
Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
T + E+ ++LEK QQ +L +L + D+ + + + Q++ +
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQ---ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
EK ++ A+ER +A + E + L +E + EL L + L
Sbjct: 1459 EEKNISSKYADERDRAEAEARE--KETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 358 ESWMS--AARAHGVE-SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--Y 412
S H +E S AL +E L + LK +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 413 ERD-KATGKLND-----LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
ERD +A + N+ L E+ + +K+ L + L E +
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 467 LCG-EEGAGSVALLSARVQQLEKSLQ---GYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ G EE + L A+++ ++ L+ RD I A KA +SL ++ + +E+
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA-KSLEADLMQLQED 1695
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A R + +++ L L L Q+ +ELE Q ++ +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 583 KVALREGGAQAD--PEELQQMR---QQLENSRIKLKR 614
+R+ QA+ EL R Q+ E++R +L+R
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 850 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 905
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 906 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 957
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 958 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 1012
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 1013 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 1062
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1116
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1117 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1176
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1177 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1224
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 67.3 bits (157), Expect = 2e-10
Identities = 122/583 (20%), Positives = 240/583 (41%), Gaps = 54/583 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1367 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1424
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1478
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1479 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1534
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1591
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1592 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1650 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1709
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1710 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
+ +RI + L + A E+ + + +E+ A + +++
Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1026
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1206
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1267 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1326
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1327 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1379
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1438
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1499 KEELERTNKMLK 1510
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 898
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 899 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 952
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 953 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 1066
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1126
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1127 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1179
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1180 KKALDE-ETRSHEAQVQEMRQK 1200
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1153 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1205
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1206 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1263
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1264 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1311 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1363
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1364 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1422
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1480
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1481 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1540 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1600 EYETELE 1606
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 942
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 943 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1001
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 1002 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1061
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 1062 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1121
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1122 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1298
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1299 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1357 EAKQNLERH 1365
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/457 (20%), Positives = 180/457 (39%), Gaps = 29/457 (6%)
Query: 181 DKEKTDLHKQIADLKD--KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKEL 237
++E+ L Q+ + + + LE ++S + Q+S+ KK + + +E + + +KE+
Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
T + E+ ++LEK QQ +L +L + D+ + + + Q++ +
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQ---ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
EK ++ A+ER +A + E + L +E + EL L + L
Sbjct: 1459 EEKNISSKYADERDRAEAEARE--KETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 358 ESWMS--AARAHGVE-SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--Y 412
S H +E S AL +E L + LK +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 413 ERD-KATGKLND-----LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
ERD +A + N+ L E+ + +K+ L + L E +
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
Query: 467 LCG-EEGAGSVALLSARVQQLEKSLQ---GYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ G EE + L A+++ ++ L+ RD I A KA +SL ++ + +E+
Sbjct: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA-KSLEADLMQLQED 1695
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A R + +++ L L L Q+ +ELE Q ++ +
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 583 KVALREGGAQAD--PEELQQMR---QQLENSRIKLKR 614
+R+ QA+ EL R Q+ E++R +L+R
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 850 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 905
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 906 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 957
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 958 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 1012
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 1013 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 1062
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1116
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1117 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1176
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1177 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1224
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 67.3 bits (157), Expect = 2e-10
Identities = 122/583 (20%), Positives = 240/583 (41%), Gaps = 54/583 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 1374 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 1431
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 1485
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 1486 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 1541
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 1598
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 1599 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1656
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 1657 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 1716
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 1717 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
+ +RI + L + A E+ + + +E+ A + +++
Sbjct: 1894 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 66.5 bits (155), Expect = 3e-10
Identities = 120/552 (21%), Positives = 237/552 (42%), Gaps = 46/552 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRV----NHQHTIRKEMQILFEEEKASLIEQHKRDERA--VS 146
++L+++ + A+A+I KLE + + + + KE ++L E + +E+A ++
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADL------------ 194
+++ + + +E + LK + + +D H+QIADL
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 195 -KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-EMLKKELVKQTSRAEQCTQLKN 252
K++ L+A ++ D K + + ++ LEG S++ E L E + +Q L
Sbjct: 1094 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 253 QLEKQNFEFQQV---TSKLKELEYERD-------SYKDWQTQSKTAQKRLCNM--AELEK 300
+LE E + T+ +EL +R+ D +T+S AQ + A+ +
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE 1213
Query: 301 EVT-RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E+T +L +R+ + NK LE++ L + L + E+ K KL + +L+S
Sbjct: 1214 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273
Query: 360 WMS---AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA-TLKYERD 415
S ARA + L++ +ES G L+ ++ T + ++
Sbjct: 1274 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE 1333
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ KLN T +R+ +E + LQ +L E +Q L+ + L + L +
Sbjct: 1334 ETRQKLNVSTKLRQLEEER-NSLQDQL----DEEMEAKQNLERHISTLNIQL--SDSKKK 1386
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
+ ++ V+ LE+ + ++ I KA + E T+ R + E V L
Sbjct: 1387 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE-LDDLVVDLDN 1445
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAE-AQKQISKELEAAQEEIKKLKVALREGGAQAD 594
QR L++ ++ ++L N +++ A ++ E EA ++E K L +A A
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 595 PEELQQMRQQLE 606
EEL++ + L+
Sbjct: 1506 KEELERTNKMLK 1517
Score = 56.0 bits (129), Expect = 4e-07
Identities = 86/382 (22%), Positives = 166/382 (43%), Gaps = 35/382 (9%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L++ T + E+ +++L+K Q+ ++LKELE + + + Q++L
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTE---EKNLLQEQLQA 905
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL----QPVQLELHEAKVKL 350
EL E +R K LEE +H++ +R+E Q +Q E + ++
Sbjct: 906 ETELYAEAEEMRVR------LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 959
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE-VAT 409
+E QLE +A + +E A +A L L EE ++
Sbjct: 960 LDLEEQLEEEEAARQKLQLEKVTA--EAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTL 467
L + K +LT ++ ES+I L+ RL ++ + RQ+L+ +++L +
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRL----KKEEKSRQELEKLKRKLEGDASD 1073
Query: 468 CGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREE 522
E+ A A ++ QL K + + +A D K AL+ +R ++ +E+
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQED 1133
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
+ R K Q+ L LE + +T++ ++ A + + + +E +E+ L
Sbjct: 1134 LDSERAARNKAEKQKRDLGEELEAL--KTELEDTLDSTATQQELRAKRE-----QEVTVL 1186
Query: 583 KVALREGGAQADPEELQQMRQQ 604
K AL E ++ ++Q+MRQ+
Sbjct: 1187 KKALDE-ETRSHEAQVQEMRQK 1207
Score = 55.6 bits (128), Expect = 5e-07
Identities = 101/487 (20%), Positives = 195/487 (40%), Gaps = 46/487 (9%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEE----KASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
T+LE ++ T ++E++ E+E K +L E+ + E V +M
Sbjct: 1160 TELEDTLDSTAT-QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV------ 1212
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+E ++ K KAN DK K L K+ ADL +L + K ++ KK ++ +Q
Sbjct: 1213 -EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA-KQEVEHKKKKLEAQVQE 1270
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDW 281
L+ S+ E +RAE L +++ K E + VT L E E + KD
Sbjct: 1271 LQSKCSDGE---------RARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
+ S Q + EL +E TR + N LR + L++ QL +EA Q ++
Sbjct: 1318 ASLSSQLQ----DTQELLQEETRQKLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLE 1370
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ ++LS + +L+ + S A E + +E+
Sbjct: 1371 RHISTLNIQLSDSKKKLQDFASTVEAL-EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1429
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
L +E+ L + D +++L ++ + L+ + ERD R + + E
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD--RAEAEARE 1487
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDP-----HAHSKALESLRN 514
KE T L +++ K L+ DL+++ D H K+ +L
Sbjct: 1488 KE-TKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERI-GPQTKVLHLTNNPAAEAQKQISKELE 573
++ + + E ++ + L +++ + G + L + E ++Q+ ++L
Sbjct: 1547 QMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 574 AAQEEIK 580
+ E++
Sbjct: 1607 EYETELE 1613
Score = 52.4 bits (120), Expect = 5e-06
Identities = 102/489 (20%), Positives = 205/489 (41%), Gaps = 55/489 (11%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E K+L + +T+L+ + +++ +L + K ++ E+ +M+ L+ E +++
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRL----AAKKQELEEILHEMEARLEEEEDRGQQLQ 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT--SKLKELEYE----RDSYKDWQTQS 285
+K++ +Q E+ + + + +Q + ++VT +K+K+LE E D +
Sbjct: 950 AERKKMAQQMLDLEEQLE-EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER 1008
Query: 286 KTAQKRL----CNMAELE---KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV----- 333
K ++R+ N+AE E K +T+L+ S+ + +L EE+ Q ++
Sbjct: 1009 KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1068
Query: 334 -------EALQPVQLELHEAKVKLSSVESQLESWMS------AARAHGVESAGALRDALE 380
E + +Q ++ E K++L+ E +L++ ++ A + + ++ L +
Sbjct: 1069 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1128
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L EE+ LK E + +R +E + L+K
Sbjct: 1129 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1188
Query: 441 RLLLVTRERDS----YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK---SLQGY 493
L TR ++ RQ+ +ELT L E+ + A L Q LEK L G
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQL--EQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 494 RDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRD----VTKLRTQRDLLTASLERI 547
++ A + K LE+ E+ + E AR + V KL+ + + +T L
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE- 1305
Query: 548 GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK-KLKVALREGGAQADPEELQQMRQQLE 606
+ K + L + A Q+ E QEE + KL V+ + + + LQ +
Sbjct: 1306 -AEGKAIKLAKD-VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 607 NSRIKLKRY 615
++ L+R+
Sbjct: 1364 EAKQNLERH 1372
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/457 (20%), Positives = 180/457 (39%), Gaps = 29/457 (6%)
Query: 181 DKEKTDLHKQIADLKD--KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKEL 237
++E+ L Q+ + + + LE ++S + Q+S+ KK + + +E + + +KE+
Sbjct: 1349 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1408
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
T + E+ ++LEK QQ +L +L + D+ + + + Q++ +
Sbjct: 1409 ENLTQQYEEKAAAYDKLEKTKNRLQQ---ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
EK ++ A+ER +A + E + L +E + EL L + L
Sbjct: 1466 EEKNISSKYADERDRAEAEARE--KETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 358 ESWMS--AARAHGVE-SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--Y 412
S H +E S AL +E L + LK +
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 413 ERD-KATGKLND-----LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
ERD +A + N+ L E+ + +K+ L + L E +
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1643
Query: 467 LCG-EEGAGSVALLSARVQQLEKSLQ---GYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ G EE + L A+++ ++ L+ RD I A KA +SL ++ + +E+
Sbjct: 1644 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKA-KSLEADLMQLQED 1702
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A R + +++ L L L Q+ +ELE Q ++ +
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 583 KVALREGGAQAD--PEELQQMR---QQLENSRIKLKR 614
+R+ QA+ EL R Q+ E++R +L+R
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Score = 38.3 bits (85), Expect = 0.080
Identities = 87/413 (21%), Positives = 164/413 (39%), Gaps = 44/413 (10%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
Q EM+ DE LQ + Q + E KEL ++ S Q T+ KN L++Q ++ ++
Sbjct: 857 QEEEMQAKEDE-LQKTKERQQKAENELKELEQKHS---QLTEEKNLLQEQLQAETELYAE 912
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
+E+ + K Q + + + E E +L+A + + + L LEE
Sbjct: 913 AEEMRVRLAAKK--QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM---LDLEE--- 964
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
QL A Q +QLE A+ K+ +E ++ E R LE +
Sbjct: 965 QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE-----RKLLEERISDLT 1019
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
E+ L ++K +++L K +E L+K +
Sbjct: 1020 TNLAEE----------EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEG 1069
Query: 448 ERDSYRQQ---LDCYEKELTVTLC--GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDP 502
+ + +Q L EL + L EE ++A L + Q +L+ R+L
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL------ 1123
Query: 503 HAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
H L+ + R +AE +RD+ +L + L +L+ Q ++
Sbjct: 1124 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV 1183
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+K + +E + + ++++ +R+ AQA EEL + +Q + ++ L +
Sbjct: 1184 TVLKKALDEETRSHEAQVQE----MRQKHAQA-VEELTEQLEQFKRAKANLDK 1231
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 67.3 bits (157), Expect = 2e-10
Identities = 122/583 (20%), Positives = 240/583 (41%), Gaps = 54/583 (9%)
Query: 32 ASTNLNFSDSTQSIKEGLSNL--LTFGKRK--SSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
++ N+ SDS + +++ S + L GK++ I ++ +K D T
Sbjct: 17 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK--TKNR 74
Query: 88 SPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS--LIEQHKRDERAV 145
E L +DL + ++ LE + RK Q+L EE+ S ++ R E
Sbjct: 75 LQQELDDLVVDLDNQRQLVSNLEKKQ------RKFDQLLAEEKNISSKYADERDRAEAEA 128
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN 202
+ E + + +K LKA + K D+ K + +L+ ++
Sbjct: 129 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE----KSK 184
Query: 203 VSNKDQISEMKKDMDEL---LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
+ + Q+ EMK ++EL LQA E A+ +E+ + L Q R Q +N+ EK+
Sbjct: 185 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE-EKR-- 241
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV-TRLRANERSLRDAIC 317
+Q+ +L E E E + + + + A+K+L ++ +LE + + ++ E +++
Sbjct: 242 --RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRK 299
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGAL 375
+ +++ +L + + E + K S+E+ L AA + A
Sbjct: 300 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLE 359
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
++ L L L +A L+ E ++ G + ++ +
Sbjct: 360 KEELAEELASSLSGRNALQDEKR---RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 416
Query: 436 HRLQKRLLL---VTRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQL 486
+L L ++ +S RQQL+ KEL L EGA ++A L A++ QL
Sbjct: 417 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 476
Query: 487 EKSL-QGYRDLIAAHDP-HAHSKALESL-------RNEVTRWREEAEGARRDVTKLRTQR 537
E+ + Q R+ AA K L+ + R +++E+AE V +L+ Q
Sbjct: 477 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 536
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
+ +RI + L + A E+ + + +E+ A + +++
Sbjct: 537 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 579
Score = 50.4 bits (115), Expect = 2e-05
Identities = 92/437 (21%), Positives = 170/437 (38%), Gaps = 27/437 (6%)
Query: 199 LEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
LE ++S + Q+S+ KK + + +E + + +KE+ T + E+ ++LEK
Sbjct: 12 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKT 71
Query: 258 NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAIC 317
QQ +L +L + D+ + + + Q++ + EK ++ A+ER +A
Sbjct: 72 KNRLQQ---ELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA 128
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS--AARAHGVE-SAGA 374
+ E + L +E + EL L + L S H +E S A
Sbjct: 129 RE--KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 186
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERD-KATGKLND-----LTT 426
L +E L + LK +ERD +A + N+ L
Sbjct: 187 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 246
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAGSVALLSARVQQ 485
E+ + +K+ L + L E + + G EE V L A+++
Sbjct: 247 QLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKD 306
Query: 486 LEKSLQ---GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTA 542
++ L+ RD I A KA +SL ++ + +E+ A R + +++ L
Sbjct: 307 FQRELEDARASRDEIFATAKENEKKA-KSLEADLMQLQEDLAAAERARKQADLEKEELAE 365
Query: 543 SLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQAD--PEELQQ 600
L L Q+ +ELE Q ++ + +R+ QA+ EL
Sbjct: 366 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT 425
Query: 601 MR---QQLENSRIKLKR 614
R Q+ E++R +L+R
Sbjct: 426 ERSTAQKNESARQQLER 442
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 66.5 bits (155), Expect = 3e-10
Identities = 98/455 (21%), Positives = 187/455 (41%), Gaps = 27/455 (5%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
+S N + +K Q+L EE+ S +RD RA ++ + ++
Sbjct: 856 QSACNLEKKQKKFDQLLAEEKTISAKYAGERD-RAEAEAREKETKALSLARALEEAMEQK 914
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---DQISEMKKDMDELLQALEGA 226
A E + L + E DL D+ + E S + Q+ EMK ++EL L+
Sbjct: 915 A-ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQA- 972
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+E L+ E+ Q +A+ L+ + E+ + +Q+ +++E+E E + + ++ +
Sbjct: 973 -TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1031
Query: 287 TAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
A+K+L ++ +LE + N + +++ + +++ + +L + + + +
Sbjct: 1032 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1091
Query: 345 EAKVKLSSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXX 401
E + KL S+E+ QL+ ++AA A RD L +
Sbjct: 1092 ENEKKLKSMEAEMIQLQEELAAAE-RAKRQAQQERDELADEI---ANSSGKGALALEEKR 1147
Query: 402 HLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV---TRERDSYRQQLDC 458
L +A L+ E ++ G + K I ++ L L ++ ++ RQQL+
Sbjct: 1148 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1207
Query: 459 YEKELTVTLCGEEGA------GSVALLSARVQQLEKSL--QGYRDLIAAHDPHAHSKALE 510
KEL V L EG S+ L A++ QLE+ L + A K L+
Sbjct: 1208 QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK 1267
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
+ +V R AE + K T+ L LE
Sbjct: 1268 DVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1302
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/236 (21%), Positives = 105/236 (44%), Gaps = 17/236 (7%)
Query: 131 KASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQ 190
+ ++ Q K +E+ + ME + A +E +L D+ K
Sbjct: 1083 REEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELA---DEIANSSGKG 1139
Query: 191 IADLKDKL-LEANVSNKDQISEMKKDMDELLQ-ALEGAQSEVEMLKKELVKQTSRAEQCT 248
L++K LEA ++ ++ E ++ EL+ L+ A +++ + +L + S A++
Sbjct: 1140 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1199
Query: 249 QLKNQLEKQNFEFQQVTSKLKELE-YERDSYKDWQT--QSKTAQ--KRLCN-MAELEKEV 302
+ QLE+QN +++ KL+E+E + YK T ++K AQ ++L N E +
Sbjct: 1200 NARQQLERQN---KELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAAC 1256
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
++R E+ L+D + L ++++ + L + K +L E + +
Sbjct: 1257 KQVRRTEKKLKDVL---LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1309
Score = 32.3 bits (70), Expect = 5.3
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 703 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 762
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 763 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 822
>AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen
MU-MB-2.42 protein.
Length = 439
Score = 66.1 bits (154), Expect = 3e-10
Identities = 91/403 (22%), Positives = 175/403 (43%), Gaps = 17/403 (4%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L G Q+E+ L++E V+++ R + T +Q+ Q S+L+ + + K +
Sbjct: 3 LSGVQAELA-LQEESVRRSERERRATL--DQVATLERSLQATESELRASQEKISKMKANE 59
Query: 283 TQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAIC-NKLLLEEQVHQLTSRVEALQPVQ 340
T+ + ++RL + + E +L RSL + ++L L ++ Q + + + +Q
Sbjct: 60 TKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQ 119
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
++ +++VK +++ +E ++ A A ES GALRD +
Sbjct: 120 RQVADSEVKAGTLQLTVER-LNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKN 178
Query: 401 XHLTEEVATLKYERDKATGKLN----DLTTVRKNQESL---IHRLQKRLLLVTRERDSYR 453
HL + + +++R +L+ L+ RK SL + L+ + + +R
Sbjct: 179 LHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAE 238
Query: 454 QQLDCYEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESL 512
QL + L GE A +V L + L++ L + +A + +L
Sbjct: 239 GQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSAL 298
Query: 513 RNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKEL 572
R E R + + KLR+ D + S E+ G + L AEAQ+QI ++L
Sbjct: 299 RLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK-GRLDRTLTGAELELAEAQRQI-QQL 356
Query: 573 EAAQEEIKKL-KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
EA +++ A E AQ ELQQ ++L +++ + +R
Sbjct: 357 EAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTER 399
Score = 36.7 bits (81), Expect = 0.24
Identities = 44/216 (20%), Positives = 94/216 (43%), Gaps = 17/216 (7%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K+ + L +Q+ L+ ++ + + + ++++ + L Q EG + + ++K ++
Sbjct: 211 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERR 270
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E+ L+ L + E ++V LE +R + + +T K +++L + + +
Sbjct: 271 LLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR--RTLDKVEREKLRSHEDTVRL 328
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL-------------QPVQLELHEAKV 348
+R+L A + Q+ QL ++V L Q QLEL +
Sbjct: 329 SAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVE 388
Query: 349 KLSSVESQLESWMSA-ARAHGVESAGALRDALESAL 383
+L S ++Q E + A RAH + L+ L+ L
Sbjct: 389 RLRSAQAQTERTLEARERAHR-QRVSTLKGQLQQEL 423
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 65.7 bits (153), Expect = 5e-10
Identities = 120/545 (22%), Positives = 224/545 (41%), Gaps = 58/545 (10%)
Query: 100 IAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXX 159
I +A+I ++ R + I E+ +K L ++ ++ + D+E
Sbjct: 916 IQLEAKIKEVTERAEEEEEINAELTA----KKRKLEDECSELKKDIDDLELTLAKVEKEK 971
Query: 160 XXXKDEFNTAAKEHKDLK---ANWDKEKTDL---HKQ-IADLKDKLLEANVSNKDQISEM 212
+++ +E L A KEK L H+Q + DL+ + + N+ K + +++
Sbjct: 972 HATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAK-TKL 1030
Query: 213 KKDMDELLQALEGAQS---EVEMLKKELVKQTSRAEQCT--------QLKNQLEKQNFEF 261
++ +D+L +LE + ++E K++L A++ T QL +LEK+ FE
Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+ SK+++ E+ Q + K Q R+ + E + RA R + +L
Sbjct: 1091 SNLISKIED---EQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Query: 321 ----LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
LEE +++VE + + E + + L Q E+ ++A R +S L
Sbjct: 1148 EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELG 1207
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKATGKLND----LTTVRK 429
+ +++ L+ E ++ K +K L D L T +
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEE 1267
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKS 489
Q+ LI+ L + + E Y +QLD EK+ V+ S + QLE+
Sbjct: 1268 EQQRLINDLTAQRARLQTEAGEYSRQLD--EKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
Query: 490 LQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE---- 545
+ L AH AL+S R++ RE+ E + K QR L A+ E
Sbjct: 1326 TKAKNAL--AH-------ALQSSRHDCDLLREQYEEEQEG--KAELQRALSKANSEVAQW 1374
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL--KVALREGGAQADPEELQQMRQ 603
R +T + T EA+K++++ L+ A+E ++ + K A E Q E++ +
Sbjct: 1375 RTKYETDAIQRTEE-LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
Query: 604 QLENS 608
+E S
Sbjct: 1434 DVERS 1438
Score = 51.2 bits (117), Expect = 1e-05
Identities = 81/406 (19%), Positives = 169/406 (41%), Gaps = 35/406 (8%)
Query: 223 LEGAQSEVEM--LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYK 279
L+ A++E EM +K+E K + + +LE++ + + L+ +++ E DS
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQ- 337
D + + + K + KEVT E + + K LE++ +L ++ L+
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 338 ---PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
V+ E H + K+ ++ ++ + A + AL++ + L
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAG-LDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQ 454
L ++V L+ ++ DL ++ E + Q+ + + ++ +
Sbjct: 1022 ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDE 1081
Query: 455 QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
+L+ E E++ + E +V + QL+K + ++L A +E L
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEI------QLQKKI---KELQAR---------IEELGE 1123
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQISKELE 573
E+ R A + + L + + ++ LE G T + L AE QK + ++LE
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQK-LRRDLE 1182
Query: 574 AAQEEIKKLKVALREGGAQADPE------ELQQMRQQLENSRIKLK 613
A + + + ALR+ A + E LQ+++Q+LE + +LK
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/198 (24%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 163 KDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN------VSNKDQISEMK 213
KDE + + K+L+ KEK DL Q+ D L +A + NK Q+
Sbjct: 863 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELE 272
K++ E + E +E+ K++L + S ++ L+ L K E +K+K L
Sbjct: 923 KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 982
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E +T +K ++++ ++ + L+A E + K LE+QV L
Sbjct: 983 EEMAGLD--ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 1040
Query: 333 VEALQPVQLELHEAKVKL 350
+E + ++++L AK KL
Sbjct: 1041 LEQEKKLRMDLERAKRKL 1058
Score = 45.6 bits (103), Expect = 5e-04
Identities = 92/457 (20%), Positives = 178/457 (38%), Gaps = 40/457 (8%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ KD+L ++ K E+++ M LL+ Q +V+ L
Sbjct: 846 AETEKEMATMKEEFQKTKDELAKSEAKRK----ELEEKMVTLLKEKNDLQLQVQSEADSL 901
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNM- 295
R EQ + K QLE + E + + +E+ E + K + + +K + ++
Sbjct: 902 ADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE 961
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV------QLELHEAKVK 349
L K A E +++ L+E + +L+ +ALQ L+ E KV
Sbjct: 962 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 350 -LSSVESQLESWMSAARAHGVESAGALRDALESAL----GXXXXXXXXXXXXXXXXXHLT 404
L+ +++LE + +E LR LE A G L
Sbjct: 1022 ILTKAKTKLEQQVDDLEG-SLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYR--------QQL 456
E++ ++E K+ D V + I LQ R+ + E ++ R Q+
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 457 DCYEKELTVTLCGEEGAGS----VALLSARVQQLEKSLQGYRDLIAAHDP------HAHS 506
D + ++ EE G+ V L R + +K + + H+ H+
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
++ L ++ + + ++ ++L+ + D L+++ E I +K +
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAI---SKAKGNLEKMCRSLED 1257
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQ 603
Q+S EL+ +EE ++L L A+ E + RQ
Sbjct: 1258 QVS-ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQ 1293
Score = 45.6 bits (103), Expect = 5e-04
Identities = 100/523 (19%), Positives = 213/523 (40%), Gaps = 45/523 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +D+ + A L+ + + + E + +EE +A L E +++ R++S
Sbjct: 1427 EVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL-EASQKESRSLST--- 1482
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
D+ T +E+K+L+ +E +DL +QIA+ ++ E K
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQ----QEISDLTEQIAEGGKQIHELEKIKK---- 1534
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLK 269
+++++ E+ ALE A++ +E + ++++ Q +++ ++ +++ E Q+
Sbjct: 1535 QVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAE---LEKEVTRLRANE---RSLRDAICNKLLLE 323
+ S D + +S+ R+ E E E+ AN SLR+ + +L+
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1654
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES-WMSAARAHGVESAGA--LRDALE 380
E L + + ++ +L + + + +++++E W + + L DA E
Sbjct: 1655 ETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASE 1714
Query: 381 SAL---GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR 437
L EV + E A K T + +
Sbjct: 1715 RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKK 1774
Query: 438 LQKRLLLVTRERDSYRQQLDCYEKELTVT--LCGEEGAGSVALLSARVQQLEKSLQGYRD 495
Q + R + + Q + + L L + G + L ARV++LE ++
Sbjct: 1775 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE---- 1830
Query: 496 LIAAHDPHAHSKALESLRNEVTRWRE---EAEGARRDVTKLRTQRDLLTASLERIGPQTK 552
++ +++A++ LR R +E + E R++V +L+ D L A ++ Q +
Sbjct: 1831 ----NEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 553 VLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALRE 588
+N +++ ELE A+E ++ KL+V RE
Sbjct: 1887 EAEEQSNANLSKFRKLQHELEEAEERAHIAESQVNKLRVKSRE 1929
Score = 45.2 bits (102), Expect = 7e-04
Identities = 84/435 (19%), Positives = 164/435 (37%), Gaps = 36/435 (8%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTS 242
EK L Q++ K + K Q+ E K + L AL+ ++ + ++L+++ ++
Sbjct: 1296 EKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQ- 1354
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
E +L+ L K N E Q +K YE D+ + + + +K + E E+ V
Sbjct: 1355 --EGKAELQRALSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKLAQRLQEAEEHV 1407
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+ A SL K L+ +V L VE L + K + + L W
Sbjct: 1408 EAVNAKCASLEKT---KQRLQNEVEDLMLDVERSNAACAALDK---KQRNFDKVLSEWKQ 1461
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
E LE++ +++ TL+ E +++
Sbjct: 1462 KYEETQAE--------LEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEIS 1513
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
DLT IH L+K V +E+ + L+ E L E G + +
Sbjct: 1514 DLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASL------EHEEGKILRIQLE 1567
Query: 483 VQQLEKSLQ---GYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGARRDVTKLRTQ 536
+ Q++ + +D H++ +E++++ + R R +A ++ + +
Sbjct: 1568 LNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNE 1627
Query: 537 RDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG-AQAD 594
++ R+ ++ + T E Q + L ++ ++L + R QA+
Sbjct: 1628 MEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAE 1687
Query: 595 PEELQQMRQQLENSR 609
EEL +Q E SR
Sbjct: 1688 IEELWATLEQTERSR 1702
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain
(1437 AA) protein.
Length = 1437
Score = 65.7 bits (153), Expect = 5e-10
Identities = 103/446 (23%), Positives = 184/446 (41%), Gaps = 50/446 (11%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K KT L +Q+ DL+ L +Q +++ D++ + LEG L +E
Sbjct: 524 KAKTKLEQQVDDLEGSL--------EQEKKLRMDLERAKRKLEGDLK----LAQESTMDN 571
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+Q QL +LEK+ FE + SK+++ E+ Q + K Q R+ + E +
Sbjct: 572 ENDKQ--QLDEKLEKKEFEISNLISKIED---EQAVEIQLQKKIKELQARIEELGEEIEA 626
Query: 302 VTRLRANERSLRDAICNKL-----LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ 356
RA R + +L LEE +++VE + + E + + L Q
Sbjct: 627 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ 686
Query: 357 LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT---EEVATLKYE 413
E+ ++A R +S L + +++ L+ E ++ K
Sbjct: 687 HEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGN 746
Query: 414 RDKATGK-----LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLC 468
+K G+ +++L T + Q+ LI+ L + + E Y +QLD EK+ V+
Sbjct: 747 LEKDGGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD--EKDALVSQL 804
Query: 469 GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARR 528
S + QLE+ + L AH AL+S R++ RE+ E +
Sbjct: 805 SRSKQASTQQIEELKHQLEEETKAKNAL--AH-------ALQSSRHDCDLLREQYEEEQE 855
Query: 529 DVTKLRTQRDLLTASLE----RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL-- 582
K QR L A+ E R +T + T EA+K++++ L+ A+E ++ +
Sbjct: 856 G--KAELQRALSKANSEVAQWRTNTETDAIQRTEE-LEEAKKKLAQRLQEAEEHVEAVNA 912
Query: 583 KVALREGGAQADPEELQQMRQQLENS 608
K A E Q E++ + +E S
Sbjct: 913 KCASLEKTKQRLQNEVEDLMLDVERS 938
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/198 (24%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 163 KDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN------VSNKDQISEMK 213
KDE + + K+L+ KEK DL Q+ D L +A + NK Q+
Sbjct: 362 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 421
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELE 272
K++ E + E +E+ K++L + S ++ L+ L K E +K+K L
Sbjct: 422 KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 481
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E +T +K ++++ ++ + L+A E + K LE+QV L
Sbjct: 482 EEMAGLD--ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 539
Query: 333 VEALQPVQLELHEAKVKL 350
+E + ++++L AK KL
Sbjct: 540 LEQEKKLRMDLERAKRKL 557
Score = 47.2 bits (107), Expect = 2e-04
Identities = 92/457 (20%), Positives = 179/457 (39%), Gaps = 39/457 (8%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ KD+L ++ K E+++ M LL+ Q +V+ L
Sbjct: 345 AETEKEMATMKEEFQKTKDELAKSEAKRK----ELEEKMVTLLKEKNDLQLQVQSEADSL 400
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNM- 295
R EQ + K QLE + E + + +E+ E + K + + +K + ++
Sbjct: 401 ADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE 460
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV------QLELHEAKVK 349
L K A E +++ L+E + +L+ +ALQ L+ E KV
Sbjct: 461 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 520
Query: 350 -LSSVESQLESWMSAARAHGVESAGALRDALESAL----GXXXXXXXXXXXXXXXXXHLT 404
L+ +++LE + +E LR LE A G L
Sbjct: 521 ILTKAKTKLEQQVDDLEG-SLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLD 579
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYR--------QQL 456
E++ ++E K+ D V + I LQ R+ + E ++ R Q+
Sbjct: 580 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 639
Query: 457 DCYEKELTVTLCGEEGAGS----VALLSARVQQLEKSLQGYRDLIAAHDP------HAHS 506
D + ++ EE G+ V L R + +K + + H+ H+
Sbjct: 640 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 699
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
++ L ++ + + ++ ++L+ + D L+++ E I +L + +
Sbjct: 700 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG--NLEKDGGRSLED 757
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQ 603
Q+S EL+ +EE ++L L A+ E + RQ
Sbjct: 758 QVS-ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQ 793
Score = 45.6 bits (103), Expect = 5e-04
Identities = 100/523 (19%), Positives = 213/523 (40%), Gaps = 45/523 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +D+ + A L+ + + + E + +EE +A L E +++ R++S
Sbjct: 927 EVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL-EASQKESRSLST--- 982
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
D+ T +E+K+L+ +E +DL +QIA+ ++ E K
Sbjct: 983 ELFKVKNVYEESLDQLETLRRENKNLQ----QEISDLTEQIAEGGKQIHELEKIKK---- 1034
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLK 269
+++++ E+ ALE A++ +E + ++++ Q +++ ++ +++ E Q+
Sbjct: 1035 QVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHT 1094
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAE---LEKEVTRLRANE---RSLRDAICNKLLLE 323
+ S D + +S+ R+ E E E+ AN SLR+ + +L+
Sbjct: 1095 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1154
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES-WMSAARAHGVESAGA--LRDALE 380
E L + + ++ +L + + + +++++E W + + L DA E
Sbjct: 1155 ETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASE 1214
Query: 381 SAL---GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR 437
L EV + E A K T + +
Sbjct: 1215 RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKK 1274
Query: 438 LQKRLLLVTRERDSYRQQLDCYEKELTVT--LCGEEGAGSVALLSARVQQLEKSLQGYRD 495
Q + R + + Q + + L L + G + L ARV++LE ++
Sbjct: 1275 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE---- 1330
Query: 496 LIAAHDPHAHSKALESLRNEVTRWRE---EAEGARRDVTKLRTQRDLLTASLERIGPQTK 552
++ +++A++ LR R +E + E R++V +L+ D L A ++ Q +
Sbjct: 1331 ----NEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1386
Query: 553 VLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALRE 588
+N +++ ELE A+E ++ KL+V RE
Sbjct: 1387 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSRE 1429
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/432 (17%), Positives = 164/432 (37%), Gaps = 33/432 (7%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
+ A +H+ + A K+ D ++ + D L + + SE+K + D+L E
Sbjct: 679 DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAE 738
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
L+K+ S +Q ++LK + E+Q +T++ L+ E Y +
Sbjct: 739 AISKAKGNLEKD--GGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE 796
Query: 285 -----SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
S+ ++ + + ++E E+ E ++A+ + L+ H E +
Sbjct: 797 KDALVSQLSRSKQASTQQIE-ELKHQLEEETKAKNALAH--ALQSSRHDCDLLREQYEEE 853
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDA-------LESALGXXXXXXXX 392
Q E + LS S++ W + ++ L +A L+ A
Sbjct: 854 QEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAK 913
Query: 393 XXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
L EV L + +++ L ++N + ++ +++ E ++
Sbjct: 914 CASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEAS 973
Query: 453 RQQLDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+++ EL V EE + L + L++ + + IA H LE
Sbjct: 974 QKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE--LEK 1031
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
++ +V + + E + A + ASLE + K+L + + + ++ ++
Sbjct: 1032 IKKQVEQEKCEIQAALEEA----------EASLEH--EEGKILRI-QLELNQVKSEVDRK 1078
Query: 572 LEAAQEEIKKLK 583
+ EEI +LK
Sbjct: 1079 IAEKDEEIDQLK 1090
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 65.3 bits (152), Expect = 6e-10
Identities = 121/589 (20%), Positives = 245/589 (41%), Gaps = 45/589 (7%)
Query: 47 EGLSNLLTFGKRKSSIGS---VDDVTPDKRLRRDS-SGNGTTAPPSPWETKRLKIDLIAA 102
E L+ ++ +++S I + V D+ + ++ +S + +E +++K +L
Sbjct: 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD--ERAVSDMEDXXXXXXXXXX 160
K + + E N H + KE ++L ++ I K + E+ S++E
Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680
Query: 161 XXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSNKDQISEMKK 214
K+ + + KE+ L D+E +L + + LK K+ + + NK+ SE K+
Sbjct: 681 SFKNLTFQLESLEKENSQL----DEENLELRRNVESLKCASMKMAQLQLENKELESE-KE 735
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ + L+ L+ + + E L E+ Q E +L+ LE N + QQ+ S+L++LE E
Sbjct: 736 QLKKGLELLKASFKKTERL--EVSYQGLDIEN-QRLQKTLENSNKKIQQLESELQDLEME 792
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ + + K + KRL +LEKE L L +K LE++ +L + E
Sbjct: 793 NQTLQKNLEELKISSKRL---EQLEKENKSLEQETSQLEK---DKKQLEKENKRLRQQAE 846
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
++ LE E VK+ ++E + ++ +S ES L++ +
Sbjct: 847 -IKDTTLE--ENNVKIGNLEKENKT-LSKEIGIYKESCVRLKELEKENKELVKRATIDIK 902
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQ----KRLLLVTRERD 450
L E + + ++L + N+E L+H Q + LL ++
Sbjct: 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLES 962
Query: 451 SYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
+ ++ L+ E+++ E S Q+L+ + Y L D ++
Sbjct: 963 TLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1020
Query: 511 SLRNEVTRWREEAEGARRDVTKLR-----TQRDLLTASLERIGPQTKVLHL-TNNPAAEA 564
+ E +W E++ R++ K++ +R+ T E+ +T++ L T N +A
Sbjct: 1021 PISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA 1080
Query: 565 Q-KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
Q + ++ + QE+ L+ + Q + L L N +L
Sbjct: 1081 QILALQRQTVSLQEQNTTLQT--QNAKLQVENSTLNSQSTSLMNQNAQL 1127
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 253 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 309
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 310 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 367 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 601
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 602 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Score = 44.4 bits (100), Expect = 0.001
Identities = 91/469 (19%), Positives = 181/469 (38%), Gaps = 49/469 (10%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 466 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 517
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 575
Query: 293 ----CNMAELEKEVTRLRANERSLRDAIC----NKLLLEEQVHQLTSRVEALQPVQLELH 344
+ ++EKE L + + + K +++++ + E + ++ ELH
Sbjct: 576 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 635
Query: 345 EAKVKLSSVESQLESW-MSAARAHGVESAGALRD----ALESALGXXXXXXXXXXXXXXX 399
+ + ++ ++ + ++ + +E + + L+ L
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 400 XXHLTEEVATLKYERDK---ATGKLNDLTTVRKNQESLIHRLQKRLLLV------TRERD 450
L EE L+ + A+ K+ L K ES +L+K L L+ T +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 451 SYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
Q LD + L TL E + L + +Q LE Q + + + SK LE
Sbjct: 756 VSYQGLDIENQRLQKTL--ENSNKKIQQLESELQDLEMENQTLQKNL--EELKISSKRLE 811
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
L E +E +D +L + L E + ++ + K +SK
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 571 ELEAAQEEIKKLKVALREG-----GAQADPEELQQMRQQLENSRIKLKR 614
E+ +E +LK +E A D + L +R+ L + ++K ++
Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Score = 38.3 bits (85), Expect = 0.080
Identities = 93/464 (20%), Positives = 182/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 325 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 624 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 681
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 739
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K+++
Sbjct: 740 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 64.5 bits (150), Expect = 1e-09
Identities = 121/590 (20%), Positives = 245/590 (41%), Gaps = 46/590 (7%)
Query: 47 EGLSNLLTFGKRKSSIGS---VDDVTPDKRLRRDS-SGNGTTAPPSPWETKRLKIDLIAA 102
E L+ ++ +++S I + V D+ + ++ +S + +E +++K +L
Sbjct: 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD--ERAVSDMEDXXXXXXXXXX 160
K + + E N H + KE ++L ++ I K + E+ S++E
Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680
Query: 161 XXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSNKDQISEMKK 214
K+ + + KE+ L D+E +L + + LK K+ + + NK+ SE K+
Sbjct: 681 SFKNLTFQLESLEKENSQL----DEENLELRRNVESLKCASMKMAQLQLENKELESE-KE 735
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ + L+ L+ + + E L E+ Q E +L+ LE N + QQ+ S+L++LE E
Sbjct: 736 QLKKGLELLKASFKKTERL--EVSYQGLDIEN-QRLQKTLENSNKKIQQLESELQDLEME 792
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ + + K + KRL +LEKE L L +K LE++ +L + E
Sbjct: 793 NQTLQKNLEELKISSKRL---EQLEKENKSLEQETSQLEK---DKKQLEKENKRLRQQAE 846
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
++ LE E VK+ ++E + ++ +S ES L++ +
Sbjct: 847 -IKDTTLE--ENNVKIGNLEKENKT-LSKEIGIYKESCVRLKELEKENKELVKRATIDIK 902
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQ-----KRLLLVTRER 449
L E + + ++L + N+E L+H Q + LL ++
Sbjct: 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE 962
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKAL 509
+ ++ L+ E+++ E S Q+L+ + Y L D ++
Sbjct: 963 STLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS 1020
Query: 510 ESLRNEVTRWREEAEGARRDVTKLR-----TQRDLLTASLERIGPQTKVLHL-TNNPAAE 563
+ E +W E++ R++ K++ +R+ T E+ +T++ L T N +
Sbjct: 1021 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080
Query: 564 AQ-KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
AQ + ++ + QE+ L+ + Q + L L N +L
Sbjct: 1081 AQILALQRQTVSLQEQNTTLQT--QNAKLQVENSTLNSQSTSLMNQNAQL 1128
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 253 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 309
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 310 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 367 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 601
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 602 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Score = 44.4 bits (100), Expect = 0.001
Identities = 91/469 (19%), Positives = 181/469 (38%), Gaps = 49/469 (10%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 466 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 517
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 575
Query: 293 ----CNMAELEKEVTRLRANERSLRDAIC----NKLLLEEQVHQLTSRVEALQPVQLELH 344
+ ++EKE L + + + K +++++ + E + ++ ELH
Sbjct: 576 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 635
Query: 345 EAKVKLSSVESQLESW-MSAARAHGVESAGALRD----ALESALGXXXXXXXXXXXXXXX 399
+ + ++ ++ + ++ + +E + + L+ L
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 400 XXHLTEEVATLKYERDK---ATGKLNDLTTVRKNQESLIHRLQKRLLLV------TRERD 450
L EE L+ + A+ K+ L K ES +L+K L L+ T +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 451 SYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
Q LD + L TL E + L + +Q LE Q + + + SK LE
Sbjct: 756 VSYQGLDIENQRLQKTL--ENSNKKIQQLESELQDLEMENQTLQKNL--EELKISSKRLE 811
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
L E +E +D +L + L E + ++ + K +SK
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 571 ELEAAQEEIKKLKVALREG-----GAQADPEELQQMRQQLENSRIKLKR 614
E+ +E +LK +E A D + L +R+ L + ++K ++
Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Score = 38.3 bits (85), Expect = 0.080
Identities = 93/464 (20%), Positives = 182/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 325 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 624 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 681
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 739
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K+++
Sbjct: 740 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 64.5 bits (150), Expect = 1e-09
Identities = 121/590 (20%), Positives = 245/590 (41%), Gaps = 46/590 (7%)
Query: 47 EGLSNLLTFGKRKSSIGS---VDDVTPDKRLRRDS-SGNGTTAPPSPWETKRLKIDLIAA 102
E L+ ++ +++S I + V D+ + ++ +S + +E +++K +L
Sbjct: 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD--ERAVSDMEDXXXXXXXXXX 160
K + + E N H + KE ++L ++ I K + E+ S++E
Sbjct: 621 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 680
Query: 161 XXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSNKDQISEMKK 214
K+ + + KE+ L D+E +L + + LK K+ + + NK+ SE K+
Sbjct: 681 SFKNLTFQLESLEKENSQL----DEENLELRRNVESLKCASMKMAQLQLENKELESE-KE 735
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ + L+ L+ + + E L E+ Q E +L+ LE N + QQ+ S+L++LE E
Sbjct: 736 QLKKGLELLKASFKKTERL--EVSYQGLDIEN-QRLQKTLENSNKKIQQLESELQDLEME 792
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ + + K + KRL +LEKE L L +K LE++ +L + E
Sbjct: 793 NQTLQKNLEELKISSKRL---EQLEKENKSLEQETSQLEK---DKKQLEKENKRLRQQAE 846
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
++ LE E VK+ ++E + ++ +S ES L++ +
Sbjct: 847 -IKDTTLE--ENNVKIGNLEKENKT-LSKEIGIYKESCVRLKELEKENKELVKRATIDIK 902
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQ-----KRLLLVTRER 449
L E + + ++L + N+E L+H Q + LL ++
Sbjct: 903 TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLE 962
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKAL 509
+ ++ L+ E+++ E S Q+L+ + Y L D ++
Sbjct: 963 STLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS 1020
Query: 510 ESLRNEVTRWREEAEGARRDVTKLR-----TQRDLLTASLERIGPQTKVLHL-TNNPAAE 563
+ E +W E++ R++ K++ +R+ T E+ +T++ L T N +
Sbjct: 1021 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080
Query: 564 AQ-KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
AQ + ++ + QE+ L+ + Q + L L N +L
Sbjct: 1081 AQILALQRQTVSLQEQNTTLQT--QNAKLQVENSTLNSQSTSLMNQNAQL 1128
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 253 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 309
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 310 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 367 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 601
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 602 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Score = 44.4 bits (100), Expect = 0.001
Identities = 91/469 (19%), Positives = 181/469 (38%), Gaps = 49/469 (10%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 466 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 517
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 575
Query: 293 ----CNMAELEKEVTRLRANERSLRDAIC----NKLLLEEQVHQLTSRVEALQPVQLELH 344
+ ++EKE L + + + K +++++ + E + ++ ELH
Sbjct: 576 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 635
Query: 345 EAKVKLSSVESQLESW-MSAARAHGVESAGALRD----ALESALGXXXXXXXXXXXXXXX 399
+ + ++ ++ + ++ + +E + + L+ L
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 400 XXHLTEEVATLKYERDK---ATGKLNDLTTVRKNQESLIHRLQKRLLLV------TRERD 450
L EE L+ + A+ K+ L K ES +L+K L L+ T +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 755
Query: 451 SYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
Q LD + L TL E + L + +Q LE Q + + + SK LE
Sbjct: 756 VSYQGLDIENQRLQKTL--ENSNKKIQQLESELQDLEMENQTLQKNL--EELKISSKRLE 811
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
L E +E +D +L + L E + ++ + K +SK
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Query: 571 ELEAAQEEIKKLKVALREG-----GAQADPEELQQMRQQLENSRIKLKR 614
E+ +E +LK +E A D + L +R+ L + ++K ++
Sbjct: 872 EIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Score = 38.3 bits (85), Expect = 0.080
Identities = 93/464 (20%), Positives = 182/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 325 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 564 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 624 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 681
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 739
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K+++
Sbjct: 740 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
>BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein.
Length = 828
Score = 64.1 bits (149), Expect = 1e-09
Identities = 124/578 (21%), Positives = 235/578 (40%), Gaps = 65/578 (11%)
Query: 74 LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS 133
L+ D TTA S + KI+++ +++ + S + T KEM +EE
Sbjct: 243 LQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRE 302
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L ++ AV++++D D+ A + ++++ EK +L +I +
Sbjct: 303 LANKY---NGAVNEIKD-----------LSDKLKVAEGKQEEIQQKGQAEKKELQHKIDE 348
Query: 194 LKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-------- 245
+++K E +I ++ D D + L Q +E L+++ +K+ S E
Sbjct: 349 MEEKEQELQA----KIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLEHLLSKSGG 404
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK---EV 302
CT + +E Q V L + E K+ QT++K + EK +
Sbjct: 405 DCTFIHQFIECQKKLI--VEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDT 462
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
T + +E+ L + + LL++ + S +EA Q +Q L + ++ + +
Sbjct: 463 TDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQ-HLRKELIEAQELARTSKQKCF 521
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKL 421
+A E A R+ +E + +L EE + + RD+
Sbjct: 522 ELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSAR 581
Query: 422 NDL-------TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAG 474
+++ V +++ I LQ+ L V E + +R+ YEKE+T + +
Sbjct: 582 DEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEIT----SLQNSF 637
Query: 475 SVALLSARVQQLEKS--LQGYRDLIA----AHDPHAHSKALES--LRNEVTRWREEAEGA 526
+ QQ E++ LQG + + A + HS E+ L +E+ R +E +
Sbjct: 638 QLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNS 697
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT---KVLHLTNN-------PAAEAQ-KQISKELEAA 575
++ +L + +L S + + Q K HL ++ AE Q K + KE E
Sbjct: 698 QKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKT 757
Query: 576 QEEIK--KLKVALREGGAQADPEELQQMRQQLENSRIK 611
Q + KLK + E Q+ +EL+Q + L+ R K
Sbjct: 758 QTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREK 795
Score = 36.7 bits (81), Expect = 0.24
Identities = 91/424 (21%), Positives = 164/424 (38%), Gaps = 26/424 (6%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQ 263
++D++ + M LQA Q+E + L+KEL+ Q + T K L + E +
Sbjct: 209 DEDRLLSRLEVMGNQLQACSKNQTE-DSLRKELIALQEDKHNYETTAKESLRRVLQEKIE 267
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
V KL E+E + +D T K +R EL + + ++D + +KL +
Sbjct: 268 VVRKLSEVERSLSNTEDECTHLKEMNER--TQEELRELANKYNGAVNEIKD-LSDKLKVA 324
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSV---ESQLESWMSAARAHGVESAGALRDALE 380
E + E Q Q E E + K+ + E +L++ + A +A + AL+
Sbjct: 325 EGKQE-----EIQQKGQAEKKELQHKIDEMEEKEQELQAKIEALQADN-DFTNERLTALQ 378
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L + T ++ + KL + K E +L K
Sbjct: 379 VRLEHLQEKTLKECSSLEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEET--KLSK 436
Query: 441 RLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAH 500
+E D EK T + + A+V L+ LQG + I A
Sbjct: 437 ENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAK 496
Query: 501 DPHAHSK-----ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLH 555
H + A E R + E + R Q + T ++ + Q + LH
Sbjct: 497 QEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLH 556
Query: 556 L-TNNPAAEAQKQISK---ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
+ T N E +I+ EL +A++EI L A + ++ D ++ ++++L+ R +
Sbjct: 557 IDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERD-TDIASLQEELKKVRAE 615
Query: 612 LKRY 615
L+R+
Sbjct: 616 LERW 619
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 64.1 bits (149), Expect = 1e-09
Identities = 107/538 (19%), Positives = 226/538 (42%), Gaps = 39/538 (7%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L+ +I LE+ +N +H +++ + FE+ K +EQHK E+ + +E
Sbjct: 350 LEQELMEKNEKIRSLETNINTEH---EKICLAFEKAKKIHLEQHKEMEKQIERLE---AQ 403
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKK 214
K++ T + +D+ L + + + K ++ + N+ + + ++
Sbjct: 404 LEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKGEMKKENMKKDEALKALQN 462
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSKLKELEY 273
+ E + S +E+ K+ELV ++ E + + QL+K++ ++V KEL+
Sbjct: 463 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKS---EEVYCLQKELKI 519
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
+ S ++ Q+ Q L ++ ++ T +R E L D + LE+QV +L
Sbjct: 520 KNHSLQETSEQNVILQHTLQQQQQMLQQET-IRNGE--LED---TQTKLEKQVSKLE--- 570
Query: 334 EALQPVQLELHEAKVKLSSVESQLESWMSAA---RAHGVESAGALRDA---LESALGXXX 387
Q +Q + + KL +E + ES A R +E G R ++
Sbjct: 571 ---QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 627
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
+ ++ L D+ +L T K E L H + L +
Sbjct: 628 KMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 687
Query: 448 ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK 507
+R+ +L EL TL + V L A++ LE+ +DL A +
Sbjct: 688 KREVLETELQNAHGELKSTLRQLQELRDV-LQKAQL-SLEEKYTTIKDLTA--ELRECKM 743
Query: 508 ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHL--TNNPAAE 563
+E + E+ + + ++ + Q L ++ E G + K++ L T +
Sbjct: 744 EIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 803
Query: 564 AQKQISKELEAAQEEIKKLKVALREGG--AQADPEELQQMRQQLENSRIKLKRYSIVL 619
K+ +K++E+ ++++ K LRE + +E+ Q+++++E ++ ++K V+
Sbjct: 804 ELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 861
Score = 56.4 bits (130), Expect = 3e-07
Identities = 115/524 (21%), Positives = 225/524 (42%), Gaps = 62/524 (11%)
Query: 110 ESRVNHQHTIRKEMQILFEE--EKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
E V QHT++++ Q+L +E L + + E+ VS +E K +
Sbjct: 529 EQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQ---------KQRES 579
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGA 226
+A K K +EK + ADLK K++E + + ++K +MD+ + L
Sbjct: 580 SAEKLRKM------EEKCESAAHEADLKRQKVIELTGTAR----QVKIEMDQYKEELSKM 629
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ E+ LK++ ++A +QL L++ E ++ T+ +KELE + S + T++
Sbjct: 630 EKEIMHLKRD---GENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEA- 685
Query: 287 TAQKRLCNMAELEKEVTRLRANERSL---RDAICN-KLLLEEQVHQLTSRVEALQPVQLE 342
QKR EL+ L++ R L RD + +L LEE+ + L+ ++E
Sbjct: 686 -LQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKME 744
Query: 343 LHEAKVKLSSVESQLE--SWMSAARAHGVESAG-ALRDALESALGXXXXXXXXXXXXXXX 399
+ + K +L ++ L+ +W RA V +R+
Sbjct: 745 IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 804
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
+++ +L + A +L + + E I +L+K + ER R
Sbjct: 805 LKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEI-----ERTQQRM----- 854
Query: 460 EKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRW 519
KE+ + +E +A L + L+ R+ + ++H++ E+ +V
Sbjct: 855 -KEMESVM--KEQEQYIATQYKEAIDLGQELRLTREQVQ----NSHTELAEARHQQVQAQ 907
Query: 520 RE--EAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHLTNNPAAEAQKQISKELEAA 575
RE D+ +L ++D L E +G + + HL AE +K +S E+E+
Sbjct: 908 REIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKK-LSAEVESL 966
Query: 576 QEEIKKLKVALREGGAQ----ADPEE--LQQMRQQLENSRIKLK 613
+E ++ +E A+ AD ++ +QQ+ +QLE ++++L+
Sbjct: 967 KEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE 1010
Score = 51.2 bits (117), Expect = 1e-05
Identities = 77/424 (18%), Positives = 168/424 (39%), Gaps = 19/424 (4%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK 235
+ ++KE+ L I +L+ KL++ N D M + E + K
Sbjct: 255 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 314
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE----RDSYKDWQTQSKTAQKR 291
+ T + Q L+ QLE++ + + +K ELE E + + +T T ++
Sbjct: 315 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEK 374
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+C E K++ L ++ + + LE++ Q + + + +Q ++ + L
Sbjct: 375 ICLAFEKAKKI-HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE 433
Query: 352 SVESQLESWMSAARAHGVESAGALR----DALESALGXXXXXXXXXXXXXXXXXHLTE-E 406
S++ L + ++ AL+ E + HL + E
Sbjct: 434 SLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 493
Query: 407 VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
K+E+ + K ++ ++K + H LQ+ + + +QQ ++E T
Sbjct: 494 GNKEKFEK-QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQE---T 549
Query: 467 LCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGA 526
+ E + L +V +LE+ LQ R+ +A + ES +E R++
Sbjct: 550 IRNGELEDTQTKLEKQVSKLEQELQKQRE-SSAEKLRKMEEKCESAAHEADLKRQKVIEL 608
Query: 527 RRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ--KQISKELEAAQEEIKKLKV 584
+++ + D L ++ + +++HL + +A Q+ L+ + E++K
Sbjct: 609 TGTARQVKIEMDQYKEELSKM--EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTN 666
Query: 585 ALRE 588
A++E
Sbjct: 667 AVKE 670
Score = 36.7 bits (81), Expect = 0.24
Identities = 81/420 (19%), Positives = 166/420 (39%), Gaps = 29/420 (6%)
Query: 192 ADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQL 250
A+L+ +L+E N + + + + +++ A E A+ KE+ KQ R E Q +
Sbjct: 348 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 407
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE------LEKEVTR 304
Q ++Q + + ++ +S T+SK K+ NM + L+ +V+
Sbjct: 408 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKE-NMKKDEALKALQNQVSE 466
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA 364
R L A+ ++ EE V L + + +L + ++ ++ +L+ +
Sbjct: 467 ETIKVRQLDSAL--EICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSL 524
Query: 365 RAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK-ATGKLND 423
+ ++ L+ L+ L ++V+ L+ E K
Sbjct: 525 QETSEQNV-ILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEK 583
Query: 424 LTTVRKNQESLIH----RLQKRLLL------VTRERDSYRQQLDCYEKELT-VTLCGEEG 472
L + + ES H + QK + L V E D Y+++L EKE+ + GE
Sbjct: 584 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 643
Query: 473 AGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE----EAEGARR 528
A ++ L + Q + L+ + + + HS E+ E + RE E + A
Sbjct: 644 AMHLSQLDMILDQTKTELEKKTNAVKELEKLQHS--TETELTEALQKREVLETELQNAHG 701
Query: 529 DVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALRE 588
++ Q L L++ + + T ++ E+E ++E+ ++ AL+E
Sbjct: 702 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE 761
Score = 35.9 bits (79), Expect = 0.43
Identities = 59/355 (16%), Positives = 142/355 (40%), Gaps = 14/355 (3%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L A ++ ++ + ++ Q+ EE+ ++ + ++ED
Sbjct: 692 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQE 751
Query: 155 XXXXXXXXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
K+ E A + L + + ++ ++I L+ L ++ + ++ E
Sbjct: 752 LLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL----ELKE 807
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
K ++ L L+ A+ ++ +KE + ++ +QLK ++E+ +++ S +KE
Sbjct: 808 CNKQIESLNDKLQNAKEQLR--EKEFI-MLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 864
Query: 272 E-YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE-EQVHQL 329
E Y YK+ + + + E+ R + + I +L E E + QL
Sbjct: 865 EQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREI-ERLSSELEDMKQL 923
Query: 330 TSRVEAL-QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ +A + EL +KV+ + +E+++++ + A A + S
Sbjct: 924 SKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAK 983
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L E++ K E ++A +++L +++ +I + LL
Sbjct: 984 WKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALL 1038
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 64.1 bits (149), Expect = 1e-09
Identities = 107/538 (19%), Positives = 226/538 (42%), Gaps = 39/538 (7%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L+ +I LE+ +N +H +++ + FE+ K +EQHK E+ + +E
Sbjct: 604 LEQELMEKNEKIRSLETNINTEH---EKICLAFEKAKKIHLEQHKEMEKQIERLE---AQ 657
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKK 214
K++ T + +D+ L + + + K ++ + N+ + + ++
Sbjct: 658 LEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKGEMKKENMKKDEALKALQN 716
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSKLKELEY 273
+ E + S +E+ K+ELV ++ E + + QL+K++ ++V KEL+
Sbjct: 717 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKS---EEVYCLQKELKI 773
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
+ S ++ Q+ Q L ++ ++ T +R E L D + LE+QV +L
Sbjct: 774 KNHSLQETSEQNVILQHTLQQQQQMLQQET-IRNGE--LED---TQTKLEKQVSKLE--- 824
Query: 334 EALQPVQLELHEAKVKLSSVESQLESWMSAA---RAHGVESAGALRDA---LESALGXXX 387
Q +Q + + KL +E + ES A R +E G R ++
Sbjct: 825 ---QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 881
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
+ ++ L D+ +L T K E L H + L +
Sbjct: 882 KMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 941
Query: 448 ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK 507
+R+ +L EL TL + V L A++ LE+ +DL A +
Sbjct: 942 KREVLETELQNAHGELKSTLRQLQELRDV-LQKAQL-SLEEKYTTIKDLTA--ELRECKM 997
Query: 508 ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHL--TNNPAAE 563
+E + E+ + + ++ + Q L ++ E G + K++ L T +
Sbjct: 998 EIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 1057
Query: 564 AQKQISKELEAAQEEIKKLKVALREGG--AQADPEELQQMRQQLENSRIKLKRYSIVL 619
K+ +K++E+ ++++ K LRE + +E+ Q+++++E ++ ++K V+
Sbjct: 1058 ELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 1115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 115/524 (21%), Positives = 225/524 (42%), Gaps = 62/524 (11%)
Query: 110 ESRVNHQHTIRKEMQILFEE--EKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
E V QHT++++ Q+L +E L + + E+ VS +E K +
Sbjct: 783 EQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQ---------KQRES 833
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGA 226
+A K K +EK + ADLK K++E + + ++K +MD+ + L
Sbjct: 834 SAEKLRKM------EEKCESAAHEADLKRQKVIELTGTAR----QVKIEMDQYKEELSKM 883
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ E+ LK++ ++A +QL L++ E ++ T+ +KELE + S + T++
Sbjct: 884 EKEIMHLKRD---GENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEA- 939
Query: 287 TAQKRLCNMAELEKEVTRLRANERSL---RDAICN-KLLLEEQVHQLTSRVEALQPVQLE 342
QKR EL+ L++ R L RD + +L LEE+ + L+ ++E
Sbjct: 940 -LQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKME 998
Query: 343 LHEAKVKLSSVESQLE--SWMSAARAHGVESAG-ALRDALESALGXXXXXXXXXXXXXXX 399
+ + K +L ++ L+ +W RA V +R+
Sbjct: 999 IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 1058
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
+++ +L + A +L + + E I +L+K + ER R
Sbjct: 1059 LKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEI-----ERTQQRM----- 1108
Query: 460 EKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRW 519
KE+ + +E +A L + L+ R+ + ++H++ E+ +V
Sbjct: 1109 -KEMESVM--KEQEQYIATQYKEAIDLGQELRLTREQVQ----NSHTELAEARHQQVQAQ 1161
Query: 520 RE--EAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHLTNNPAAEAQKQISKELEAA 575
RE D+ +L ++D L E +G + + HL AE +K +S E+E+
Sbjct: 1162 REIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKK-LSAEVESL 1220
Query: 576 QEEIKKLKVALREGGAQ----ADPEE--LQQMRQQLENSRIKLK 613
+E ++ +E A+ AD ++ +QQ+ +QLE ++++L+
Sbjct: 1221 KEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE 1264
Score = 51.2 bits (117), Expect = 1e-05
Identities = 77/424 (18%), Positives = 168/424 (39%), Gaps = 19/424 (4%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK 235
+ ++KE+ L I +L+ KL++ N D M + E + K
Sbjct: 509 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 568
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE----RDSYKDWQTQSKTAQKR 291
+ T + Q L+ QLE++ + + +K ELE E + + +T T ++
Sbjct: 569 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEK 628
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+C E K++ L ++ + + LE++ Q + + + +Q ++ + L
Sbjct: 629 ICLAFEKAKKI-HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE 687
Query: 352 SVESQLESWMSAARAHGVESAGALR----DALESALGXXXXXXXXXXXXXXXXXHLTE-E 406
S++ L + ++ AL+ E + HL + E
Sbjct: 688 SLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 747
Query: 407 VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
K+E+ + K ++ ++K + H LQ+ + + +QQ ++E T
Sbjct: 748 GNKEKFEK-QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQE---T 803
Query: 467 LCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGA 526
+ E + L +V +LE+ LQ R+ +A + ES +E R++
Sbjct: 804 IRNGELEDTQTKLEKQVSKLEQELQKQRE-SSAEKLRKMEEKCESAAHEADLKRQKVIEL 862
Query: 527 RRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ--KQISKELEAAQEEIKKLKV 584
+++ + D L ++ + +++HL + +A Q+ L+ + E++K
Sbjct: 863 TGTARQVKIEMDQYKEELSKM--EKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTN 920
Query: 585 ALRE 588
A++E
Sbjct: 921 AVKE 924
Score = 38.7 bits (86), Expect = 0.060
Identities = 62/373 (16%), Positives = 149/373 (39%), Gaps = 14/373 (3%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L A ++ ++ + ++ Q+ EE+ ++ + ++ED
Sbjct: 946 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQE 1005
Query: 155 XXXXXXXXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
K+ E A + L + + ++ ++I L+ L ++ + ++ E
Sbjct: 1006 LLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL----ELKE 1061
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
K ++ L L+ A+ ++ +KE + ++ +QLK ++E+ +++ S +KE
Sbjct: 1062 CNKQIESLNDKLQNAKEQLR--EKEFI-MLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 1118
Query: 272 E-YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE-EQVHQL 329
E Y YK+ + + + E+ R + + I +L E E + QL
Sbjct: 1119 EQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREI-ERLSSELEDMKQL 1177
Query: 330 TSRVEAL-QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ +A + EL +KV+ + +E+++++ + A A + S
Sbjct: 1178 SKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAK 1237
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
L E++ K E ++A +++L +++ +I + LL E
Sbjct: 1238 WKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESE 1297
Query: 449 RDSYRQQLDCYEK 461
+ ++ +EK
Sbjct: 1298 LTRLQAKISGHEK 1310
Score = 38.3 bits (85), Expect = 0.080
Identities = 61/291 (20%), Positives = 120/291 (41%), Gaps = 16/291 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-------ER 143
E +LK+DL+ Q + E + N +E+ F++ K + E+ ++ ER
Sbjct: 216 ECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILER 275
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA--NWDKEKTDLHK-QIADLKDKLLE 200
+++ E K E ++ + LK N KEK + + +++ +L E
Sbjct: 276 NLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTE 335
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+ S SE+ ++ DE+L+ +E LK + Q R + C Q ++E E
Sbjct: 336 SRQSILKLESEL-ENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQ---EIESSRVE 391
Query: 261 FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
+ + + +L +R+ + SK N + ++ + AN+ + +
Sbjct: 392 LRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSN--KEDRCIGCCEANKLVISELRIKLA 449
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+ E ++ +L + + A Q Q + + SS S LE+ H VES
Sbjct: 450 IKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVES 500
Score = 36.7 bits (81), Expect = 0.24
Identities = 81/420 (19%), Positives = 166/420 (39%), Gaps = 29/420 (6%)
Query: 192 ADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQL 250
A+L+ +L+E N + + + + +++ A E A+ KE+ KQ R E Q +
Sbjct: 602 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 661
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE------LEKEVTR 304
Q ++Q + + ++ +S T+SK K+ NM + L+ +V+
Sbjct: 662 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKE-NMKKDEALKALQNQVSE 720
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA 364
R L A+ ++ EE V L + + +L + ++ ++ +L+ +
Sbjct: 721 ETIKVRQLDSAL--EICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSL 778
Query: 365 RAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK-ATGKLND 423
+ ++ L+ L+ L ++V+ L+ E K
Sbjct: 779 QETSEQNV-ILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEK 837
Query: 424 LTTVRKNQESLIH----RLQKRLLL------VTRERDSYRQQLDCYEKELT-VTLCGEEG 472
L + + ES H + QK + L V E D Y+++L EKE+ + GE
Sbjct: 838 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 897
Query: 473 AGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE----EAEGARR 528
A ++ L + Q + L+ + + + HS E+ E + RE E + A
Sbjct: 898 AMHLSQLDMILDQTKTELEKKTNAVKELEKLQHS--TETELTEALQKREVLETELQNAHG 955
Query: 529 DVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALRE 588
++ Q L L++ + + T ++ E+E ++E+ ++ AL+E
Sbjct: 956 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE 1015
Score = 34.3 bits (75), Expect = 1.3
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 8/134 (5%)
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHS--KALESLRNEVTRWREEA---EGARRD 529
S A + ++ L + L R A HS ES+ E+T+ R + E A++
Sbjct: 105 SSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQ 164
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ-ISKE--LEAAQEEIKKLKVAL 586
+ + + + Q KVL N ++QK I KE L+ ++EE KLKV L
Sbjct: 165 AASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDL 224
Query: 587 REGGAQADPEELQQ 600
E Q E Q+
Sbjct: 225 LEQTKQGKRAERQR 238
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 63.3 bits (147), Expect = 2e-09
Identities = 94/444 (21%), Positives = 178/444 (40%), Gaps = 34/444 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSARV--QQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGGAQADPEELQQMRQQLENSR 609
R QA+ EEL+ + +Q E SR
Sbjct: 1675 ERRNNLQAELEELRAVVEQTERSR 1698
Score = 47.6 bits (108), Expect = 1e-04
Identities = 85/407 (20%), Positives = 171/407 (42%), Gaps = 38/407 (9%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTALKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R++
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGA---------RRDVTKLRTQ 536
LE+ L+ R A + + E E++ EEA GA +R+ + +
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRE--LEEISERLEEAGGATSCQIEMNKKREAEFQKMR 1175
Query: 537 RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
RDL A+L+ + + AE +QI L+ +++++K K
Sbjct: 1176 RDLEEATLQHEATAAALRKKHADSVAELGEQID-NLQRVKQKLEKEK 1221
Score = 41.9 bits (94), Expect = 0.006
Identities = 34/183 (18%), Positives = 92/183 (50%), Gaps = 14/183 (7%)
Query: 199 LEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE----QCTQLKNQL 254
L+ N++ ++ + ++ +++EL +E + ++ +EL++ + R + Q T L NQ
Sbjct: 1667 LKENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQK 1726
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
+K + + Q+ ++++E + ++ + + A+K + + A + +E+ + + L
Sbjct: 1727 KKMDADLSQLQTEVEE------AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1780
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-KLSSVESQLESWMSAARAHGVESAG 373
K +E+ + L R++ + + L+ + ++ KL + +LE+ + A + ES
Sbjct: 1781 M---KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1837
Query: 374 ALR 376
+R
Sbjct: 1838 GMR 1840
Score = 40.7 bits (91), Expect = 0.015
Identities = 80/373 (21%), Positives = 144/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTALKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S + E+ + RE E + RRD+ +
Sbjct: 1124 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 63.3 bits (147), Expect = 2e-09
Identities = 121/553 (21%), Positives = 235/553 (42%), Gaps = 59/553 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDERAVSD 147
E RL+++L A KA +KL++ +++ T+ +E + I F ++ ASL Q + + + +
Sbjct: 1270 EGDRLRVEL-AEKA--SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAK---EHKDLKANWDKEKTDLHKQIADLKDKLLEANVS 204
++E N+ + E ++ + N +K+ L Q+AD K K+ + ++
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV-DDDLG 1385
Query: 205 NKDQISEMKK----DMDELLQALEG---AQSEVEMLKKELVKQ----TSRAEQCTQLKNQ 253
+ + E KK D + L Q LE A ++E K L ++ T + Q+ +
Sbjct: 1386 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1445
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
LEK+ +F Q+ ++ K + ++ A++R AE ++ T+ + R+L
Sbjct: 1446 LEKKQKKFDQLLAEEKSI------------SARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
+A+ K E Q QL + +E L + ++ + +L + LE + R E
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE--- 1550
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
L D L++ ++ T + ++ L + VR+ +
Sbjct: 1551 -LEDELQA---TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL--IKQVRELEAE 1604
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG---EEGAGSVALLSARVQQLEKSL 490
L ++R L V ++ + ++D + E + +E + L A+++ ++ L
Sbjct: 1605 LEDERKQRALAVASKK---KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 491 Q---GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+ RD I A + K L+SL E+ + +EE + R +RD L +
Sbjct: 1662 EEARASRDEIFAQSKESEKK-LKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 548 GPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR-- 602
L L EA+ Q+ +ELE Q ++ L R+ Q D EL R
Sbjct: 1721 ASGKSAL-LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Query: 603 -QQLENSRIKLKR 614
Q+ +N+R +L+R
Sbjct: 1780 AQKSDNARQQLER 1792
Score = 58.8 bits (136), Expect = 5e-08
Identities = 105/495 (21%), Positives = 198/495 (40%), Gaps = 62/495 (12%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E +D +EK +A ++ LEA + Q +++ DM++L+ + + V
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-----DWQTQSK 286
L+K + + +Q +++ QLE+ E Q LE + K D QT+ +
Sbjct: 1529 ELEK---SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++ + + +E+ +ER R A+ +K +E + L +++EA + E+ +
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDA---LESALGXXXXXXXXXXXXXXXXXH 402
KL + + + ARA E +++ L+S H
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
Query: 403 LTEEVATLKYE-RDKATGKL-----------------NDLTTVRKNQESLIHRLQKRLLL 444
+E L E + A+GK +L + N E L R +K L
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
Query: 445 V-------------TRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQ 485
V ++ D+ RQQL+ KEL L EGA +++ L A++ Q
Sbjct: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ A + A +K + ++ + E RR + + Q + A ++
Sbjct: 1826 LEEQLEQ-----EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALREGGAQADPEEL 598
++ Q + A +++++ +EL+ A E E+ LK LR GG +
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR 1940
Query: 599 QQMRQ-QLENSRIKL 612
RQ LE + ++L
Sbjct: 1941 SGRRQLHLEGASLEL 1955
Score = 56.8 bits (131), Expect = 2e-07
Identities = 88/375 (23%), Positives = 160/375 (42%), Gaps = 36/375 (9%)
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
Q T+ + +L+ ++ E +V K ++E E + + Q + L + E E+
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA- 904
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWM 361
A E R A K LEE +H L SRV E Q +Q E + + + +E QL+
Sbjct: 905 EAEEMRARLA-AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 362 SAARAHGVESAGA---LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
A + +E A ++ E L + E + L E +KA
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA- 1022
Query: 419 GKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL---TVTLCGE--EGA 473
+L +R QE +I L++RL ++ + RQ+L+ +++L T L + E
Sbjct: 1023 ---KNLAKIRNKQEVMISDLEERL----KKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHS----KALESLRNEVTRWREEAEGARRD 529
+ L ++ + E+ LQG L D H K + L+ ++ +E+ E +
Sbjct: 1076 AQIDELKLQLAKKEEELQG--ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG 589
K Q+ L+ LE + +T++ + AA+ + + +E +E+ +LK AL E
Sbjct: 1134 RNKAEKQKRDLSEELEAL--KTELEDTLDTTAAQQELRTKRE-----QEVAELKKALEE- 1185
Query: 590 GAQADPEELQQMRQQ 604
+ ++Q MRQ+
Sbjct: 1186 ETKNHEAQIQDMRQR 1200
Score = 46.4 bits (105), Expect = 3e-04
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 24/279 (8%)
Query: 93 KRLKIDLIAAKAQI---TKLESRVNHQ----HTIRKEMQILFEEEKAS---LIEQHKRDE 142
K+++IDL +AQI K V Q K+ Q EE +AS + Q K E
Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN 202
+ + +E + A++ +D A+ + D K +L EA
Sbjct: 1680 KKLKSLE-AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EAR 1737
Query: 203 VSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
++ ++++ E + +M+ L +V+ L EL + S A++ + QLE+QN
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN--- 1794
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+++ +KL+ELE S K T S K + +LE+++ + A ER+ + + +
Sbjct: 1795 KELKAKLQELEGAVKS-KFKATISALEAK----IGQLEEQLEQ-EAKERAAANKLVRRTE 1848
Query: 321 -LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
L+E Q+ + ++ +A ++ ++ QLE
Sbjct: 1849 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887
Score = 41.1 bits (92), Expect = 0.011
Identities = 91/502 (18%), Positives = 189/502 (37%), Gaps = 40/502 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRV---NHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
++L+++ + A+A+I K+E + Q++ + + L E+ A Q +E ++
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ K ++L +K K L + DL+D++ E +
Sbjct: 1027 KIRNKQEVMISDLEERLKKEEKTRQEL----EKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++ K +EL AL E L Q +L+ E + + + +
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L E ++ K + + AQ+ L + E+EV L+ ++L + N E Q+
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQEL--RTKREQEVAELK---KALEEETKNH---EAQI 1194
Query: 327 HQLTSR-VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
+ R AL+ + +L +AK ++ LE E A ++ L+
Sbjct: 1195 QDMRQRHATALEELSEQLEQAK----RFKANLEKNKQGLETDNKELACEVK-VLQQVKAE 1249
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYE-RDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
E L+ E +KA+ N+L N +L+ +K+ +
Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL----DNVSTLLEEAEKKGIK 1305
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA 504
++ S QL ++ L +E LS+R++QLE+ ++
Sbjct: 1306 FAKDAASLESQLQDTQELL------QEETRQKLNLSSRIRQLEEEKNSLQE-----QQEE 1354
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEA 564
+A ++L +V + + ++ V + L + +++ + L A A
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 565 QKQISKELEAAQEEIKKLKVAL 586
++ K Q+E+ L V L
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDL 1436
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 63.3 bits (147), Expect = 2e-09
Identities = 121/553 (21%), Positives = 235/553 (42%), Gaps = 59/553 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDERAVSD 147
E RL+++L A KA +KL++ +++ T+ +E + I F ++ ASL Q + + + +
Sbjct: 1270 EGDRLRVEL-AEKA--SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAK---EHKDLKANWDKEKTDLHKQIADLKDKLLEANVS 204
++E N+ + E ++ + N +K+ L Q+AD K K+ + ++
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV-DDDLG 1385
Query: 205 NKDQISEMKK----DMDELLQALEG---AQSEVEMLKKELVKQ----TSRAEQCTQLKNQ 253
+ + E KK D + L Q LE A ++E K L ++ T + Q+ +
Sbjct: 1386 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1445
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
LEK+ +F Q+ ++ K + ++ A++R AE ++ T+ + R+L
Sbjct: 1446 LEKKQKKFDQLLAEEKSI------------SARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
+A+ K E Q QL + +E L + ++ + +L + LE + R E
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE--- 1550
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
L D L++ ++ T + ++ L + VR+ +
Sbjct: 1551 -LEDELQA---TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL--IKQVRELEAE 1604
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG---EEGAGSVALLSARVQQLEKSL 490
L ++R L V ++ + ++D + E + +E + L A+++ ++ L
Sbjct: 1605 LEDERKQRALAVASKK---KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 491 Q---GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+ RD I A + K L+SL E+ + +EE + R +RD L +
Sbjct: 1662 EEARASRDEIFAQSKESEKK-LKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 548 GPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR-- 602
L L EA+ Q+ +ELE Q ++ L R+ Q D EL R
Sbjct: 1721 ASGKSAL-LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Query: 603 -QQLENSRIKLKR 614
Q+ +N+R +L+R
Sbjct: 1780 AQKSDNARQQLER 1792
Score = 58.8 bits (136), Expect = 5e-08
Identities = 105/495 (21%), Positives = 198/495 (40%), Gaps = 62/495 (12%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E +D +EK +A ++ LEA + Q +++ DM++L+ + + V
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-----DWQTQSK 286
L+K + + +Q +++ QLE+ E Q LE + K D QT+ +
Sbjct: 1529 ELEK---SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++ + + +E+ +ER R A+ +K +E + L +++EA + E+ +
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDA---LESALGXXXXXXXXXXXXXXXXXH 402
KL + + + ARA E +++ L+S H
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
Query: 403 LTEEVATLKYE-RDKATGKL-----------------NDLTTVRKNQESLIHRLQKRLLL 444
+E L E + A+GK +L + N E L R +K L
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
Query: 445 V-------------TRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQ 485
V ++ D+ RQQL+ KEL L EGA +++ L A++ Q
Sbjct: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ A + A +K + ++ + E RR + + Q + A ++
Sbjct: 1826 LEEQLEQ-----EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALREGGAQADPEEL 598
++ Q + A +++++ +EL+ A E E+ LK LR GG +
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR 1940
Query: 599 QQMRQ-QLENSRIKL 612
RQ LE + ++L
Sbjct: 1941 SGRRQLHLEGASLEL 1955
Score = 56.8 bits (131), Expect = 2e-07
Identities = 88/375 (23%), Positives = 160/375 (42%), Gaps = 36/375 (9%)
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
Q T+ + +L+ ++ E +V K ++E E + + Q + L + E E+
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA- 904
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWM 361
A E R A K LEE +H L SRV E Q +Q E + + + +E QL+
Sbjct: 905 EAEEMRARLA-AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 362 SAARAHGVESAGA---LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
A + +E A ++ E L + E + L E +KA
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA- 1022
Query: 419 GKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL---TVTLCGE--EGA 473
+L +R QE +I L++RL ++ + RQ+L+ +++L T L + E
Sbjct: 1023 ---KNLAKIRNKQEVMISDLEERL----KKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHS----KALESLRNEVTRWREEAEGARRD 529
+ L ++ + E+ LQG L D H K + L+ ++ +E+ E +
Sbjct: 1076 AQIDELKLQLAKKEEELQG--ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG 589
K Q+ L+ LE + +T++ + AA+ + + +E +E+ +LK AL E
Sbjct: 1134 RNKAEKQKRDLSEELEAL--KTELEDTLDTTAAQQELRTKRE-----QEVAELKKALEE- 1185
Query: 590 GAQADPEELQQMRQQ 604
+ ++Q MRQ+
Sbjct: 1186 ETKNHEAQIQDMRQR 1200
Score = 46.4 bits (105), Expect = 3e-04
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 24/279 (8%)
Query: 93 KRLKIDLIAAKAQI---TKLESRVNHQ----HTIRKEMQILFEEEKAS---LIEQHKRDE 142
K+++IDL +AQI K V Q K+ Q EE +AS + Q K E
Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN 202
+ + +E + A++ +D A+ + D K +L EA
Sbjct: 1680 KKLKSLE-AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EAR 1737
Query: 203 VSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
++ ++++ E + +M+ L +V+ L EL + S A++ + QLE+QN
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN--- 1794
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+++ +KL+ELE S K T S K + +LE+++ + A ER+ + + +
Sbjct: 1795 KELKAKLQELEGAVKS-KFKATISALEAK----IGQLEEQLEQ-EAKERAAANKLVRRTE 1848
Query: 321 -LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
L+E Q+ + ++ +A ++ ++ QLE
Sbjct: 1849 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887
Score = 41.1 bits (92), Expect = 0.011
Identities = 91/502 (18%), Positives = 189/502 (37%), Gaps = 40/502 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRV---NHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
++L+++ + A+A+I K+E + Q++ + + L E+ A Q +E ++
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1026
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ K ++L +K K L + DL+D++ E +
Sbjct: 1027 KIRNKQEVMISDLEERLKKEEKTRQEL----EKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++ K +EL AL E L Q +L+ E + + + +
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L E ++ K + + AQ+ L + E+EV L+ ++L + N E Q+
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQEL--RTKREQEVAELK---KALEEETKNH---EAQI 1194
Query: 327 HQLTSR-VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
+ R AL+ + +L +AK ++ LE E A ++ L+
Sbjct: 1195 QDMRQRHATALEELSEQLEQAK----RFKANLEKNKQGLETDNKELACEVK-VLQQVKAE 1249
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYE-RDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
E L+ E +KA+ N+L N +L+ +K+ +
Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL----DNVSTLLEEAEKKGIK 1305
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA 504
++ S QL ++ L +E LS+R++QLE+ ++
Sbjct: 1306 FAKDAASLESQLQDTQELL------QEETRQKLNLSSRIRQLEEEKNSLQE-----QQEE 1354
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEA 564
+A ++L +V + + ++ V + L + +++ + L A A
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 565 QKQISKELEAAQEEIKKLKVAL 586
++ K Q+E+ L V L
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDL 1436
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 63.3 bits (147), Expect = 2e-09
Identities = 121/553 (21%), Positives = 235/553 (42%), Gaps = 59/553 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDERAVSD 147
E RL+++L A KA +KL++ +++ T+ +E + I F ++ ASL Q + + + +
Sbjct: 1270 EGDRLRVEL-AEKA--SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAK---EHKDLKANWDKEKTDLHKQIADLKDKLLEANVS 204
++E N+ + E ++ + N +K+ L Q+AD K K+ + ++
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV-DDDLG 1385
Query: 205 NKDQISEMKK----DMDELLQALEG---AQSEVEMLKKELVKQ----TSRAEQCTQLKNQ 253
+ + E KK D + L Q LE A ++E K L ++ T + Q+ +
Sbjct: 1386 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASN 1445
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
LEK+ +F Q+ ++ K + ++ A++R AE ++ T+ + R+L
Sbjct: 1446 LEKKQKKFDQLLAEEKSI------------SARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
+A+ K E Q QL + +E L + ++ + +L + LE + R E
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE--- 1550
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
L D L++ ++ T + ++ L + VR+ +
Sbjct: 1551 -LEDELQA---TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL--IKQVRELEAE 1604
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG---EEGAGSVALLSARVQQLEKSL 490
L ++R L V ++ + ++D + E + +E + L A+++ ++ L
Sbjct: 1605 LEDERKQRALAVASKK---KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1661
Query: 491 Q---GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+ RD I A + K L+SL E+ + +EE + R +RD L +
Sbjct: 1662 EEARASRDEIFAQSKESEKK-LKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 548 GPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR-- 602
L L EA+ Q+ +ELE Q ++ L R+ Q D EL R
Sbjct: 1721 ASGKSAL-LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779
Query: 603 -QQLENSRIKLKR 614
Q+ +N+R +L+R
Sbjct: 1780 AQKSDNARQQLER 1792
Score = 58.8 bits (136), Expect = 5e-08
Identities = 105/495 (21%), Positives = 198/495 (40%), Gaps = 62/495 (12%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E +D +EK +A ++ LEA + Q +++ DM++L+ + + V
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1528
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-----DWQTQSK 286
L+K + + +Q +++ QLE+ E Q LE + K D QT+ +
Sbjct: 1529 ELEK---SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1585
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++ + + +E+ +ER R A+ +K +E + L +++EA + E+ +
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDA---LESALGXXXXXXXXXXXXXXXXXH 402
KL + + + ARA E +++ L+S H
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
Query: 403 LTEEVATLKYE-RDKATGKL-----------------NDLTTVRKNQESLIHRLQKRLLL 444
+E L E + A+GK +L + N E L R +K L
Sbjct: 1706 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1765
Query: 445 V-------------TRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQ 485
V ++ D+ RQQL+ KEL L EGA +++ L A++ Q
Sbjct: 1766 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1825
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ A + A +K + ++ + E RR + + Q + A ++
Sbjct: 1826 LEEQLEQ-----EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1880
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALREGGAQADPEEL 598
++ Q + A +++++ +EL+ A E E+ LK LR GG +
Sbjct: 1881 QLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR 1940
Query: 599 QQMRQ-QLENSRIKL 612
RQ LE + ++L
Sbjct: 1941 SGRRQLHLEGASLEL 1955
Score = 56.8 bits (131), Expect = 2e-07
Identities = 88/375 (23%), Positives = 160/375 (42%), Gaps = 36/375 (9%)
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
Q T+ + +L+ ++ E +V K ++E E + + Q + L + E E+
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA- 904
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWM 361
A E R A K LEE +H L SRV E Q +Q E + + + +E QL+
Sbjct: 905 EAEEMRARLA-AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 362 SAARAHGVESAGA---LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
A + +E A ++ E L + E + L E +KA
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA- 1022
Query: 419 GKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL---TVTLCGE--EGA 473
+L +R QE +I L++RL ++ + RQ+L+ +++L T L + E
Sbjct: 1023 ---KNLAKIRNKQEVMISDLEERL----KKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHS----KALESLRNEVTRWREEAEGARRD 529
+ L ++ + E+ LQG L D H K + L+ ++ +E+ E +
Sbjct: 1076 AQIDELKLQLAKKEEELQG--ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG 589
K Q+ L+ LE + +T++ + AA+ + + +E +E+ +LK AL E
Sbjct: 1134 RNKAEKQKRDLSEELEAL--KTELEDTLDTTAAQQELRTKRE-----QEVAELKKALEE- 1185
Query: 590 GAQADPEELQQMRQQ 604
+ ++Q MRQ+
Sbjct: 1186 ETKNHEAQIQDMRQR 1200
Score = 52.4 bits (120), Expect = 5e-06
Identities = 115/571 (20%), Positives = 227/571 (39%), Gaps = 60/571 (10%)
Query: 91 ETKRLKIDLIAAKAQITK----LESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAV 145
E + ++ L A K ++ + LESRV + + QIL E+K ++ H +D E +
Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEE---ERNQILQNEKKK--MQAHIQDLEEQL 959
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEH---KDLKANWDKEKTDLHKQIADLKDKLLE-- 200
+ E + + +E +D + + KEK + +IA+ +L E
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019
Query: 201 ------ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQ 253
A + NK ++ M D++E L+ E + E+E K++L +T+ + Q +L+ Q
Sbjct: 1020 EKAKNLAKIRNKQEV--MISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 254 LEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN---- 308
+++ + + +L+ L D K ++ +AEL+++ +A+
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 309 ERSLRDAI----CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA 364
E+ RD K LE+ + ++ E + E+ E K L E+ +
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDM 1197
Query: 365 RAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDL 424
R + L + LE A L EV L+ + ++ K
Sbjct: 1198 RQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHK---- 1253
Query: 425 TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLCGEEGAGSVALLSARV 483
RK ++ + L ++ R R ++ + EL V+ EE +
Sbjct: 1254 ---RKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDA 1310
Query: 484 QQLEKSLQGYRDLIAAHDPH-----AHSKALESLRNEVTRWREEAEGARRDVTK-LRTQR 537
LE LQ ++L+ + + LE +N + +EE E AR+++ K + +
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL-----KVALREGGAQ 592
L + +++ T EA+K++ K+ EA + +++ K+ + Q
Sbjct: 1371 SQLADTKKKVDDDLG----TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ 1426
Query: 593 ADPE----ELQQMRQQLENSRIKLKRYSIVL 619
+P+ +L RQ N K K++ +L
Sbjct: 1427 QEPDDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Score = 46.4 bits (105), Expect = 3e-04
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 24/279 (8%)
Query: 93 KRLKIDLIAAKAQI---TKLESRVNHQ----HTIRKEMQILFEEEKAS---LIEQHKRDE 142
K+++IDL +AQI K V Q K+ Q EE +AS + Q K E
Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN 202
+ + +E + A++ +D A+ + D K +L EA
Sbjct: 1680 KKLKSLE-AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EAR 1737
Query: 203 VSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
++ ++++ E + +M+ L +V+ L EL + S A++ + QLE+QN
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN--- 1794
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+++ +KL+ELE S K T S K + +LE+++ + A ER+ + + +
Sbjct: 1795 KELKAKLQELEGAVKS-KFKATISALEAK----IGQLEEQLEQ-EAKERAAANKLVRRTE 1848
Query: 321 -LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
L+E Q+ + ++ +A ++ ++ QLE
Sbjct: 1849 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887
Score = 44.0 bits (99), Expect = 0.002
Identities = 84/426 (19%), Positives = 173/426 (40%), Gaps = 32/426 (7%)
Query: 117 HTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN----TAAKE 172
H + K + L E++ + Q + E + ED K +F T ++
Sbjct: 1528 HELEKSKRAL-EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-E 231
+++ K K+ +L ++ D + + A S K ++K D++ ++A A+ EV +
Sbjct: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK-DLEAQIEAANKARDEVIK 1645
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
L+K + + + + ++ + ++ KLK LE E ++ S+ A++
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1705
Query: 292 L-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKL 350
EL E+T + + +L D K LE ++ QL +E Q L++ K
Sbjct: 1706 AEQERDELADEITNSASGKSALLD---EKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 1762
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATL 410
+ L + ++A R+ +S A R LE T ++ L
Sbjct: 1763 TLQVDTLNAELAAERSAAQKSDNA-RQQLERQNKELKAKLQELEGAVKSKFKAT--ISAL 1819
Query: 411 KYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
+ + + +L R L+ R +K+L + + + R+ D Y++++
Sbjct: 1820 EAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM------- 1872
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
E A +AR++QL++ L+ A + + + L+ E+ E EG R+V
Sbjct: 1873 EKA------NARMKQLKRQLEE-----AEEEATRANASRRKLQRELDDATEANEGLSREV 1921
Query: 531 TKLRTQ 536
+ L+ +
Sbjct: 1922 STLKNR 1927
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 63.3 bits (147), Expect = 2e-09
Identities = 121/553 (21%), Positives = 235/553 (42%), Gaps = 59/553 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDERAVSD 147
E RL+++L A KA +KL++ +++ T+ +E + I F ++ ASL Q + + + +
Sbjct: 1312 EGDRLRVEL-AEKA--SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1368
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAK---EHKDLKANWDKEKTDLHKQIADLKDKLLEANVS 204
++E N+ + E ++ + N +K+ L Q+AD K K+ + ++
Sbjct: 1369 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV-DDDLG 1427
Query: 205 NKDQISEMKK----DMDELLQALEG---AQSEVEMLKKELVKQ----TSRAEQCTQLKNQ 253
+ + E KK D + L Q LE A ++E K L ++ T + Q+ +
Sbjct: 1428 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1487
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
LEK+ +F Q+ ++ K + ++ A++R AE ++ T+ + R+L
Sbjct: 1488 LEKKQKKFDQLLAEEKSI------------SARYAEERDRAEAEAREKETKALSLARALE 1535
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
+A+ K E Q QL + +E L + ++ + +L + LE + R E
Sbjct: 1536 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE--- 1592
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
L D L++ ++ T + ++ L + VR+ +
Sbjct: 1593 -LEDELQA---TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL--IKQVRELEAE 1646
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG---EEGAGSVALLSARVQQLEKSL 490
L ++R L V ++ + ++D + E + +E + L A+++ ++ L
Sbjct: 1647 LEDERKQRALAVASKK---KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL 1703
Query: 491 Q---GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+ RD I A + K L+SL E+ + +EE + R +RD L +
Sbjct: 1704 EEARASRDEIFAQSKESEKK-LKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1762
Query: 548 GPQTKVLHLTNNPAAEAQ-KQISKELEAAQEEIKKLKVALREGGAQADP--EELQQMR-- 602
L L EA+ Q+ +ELE Q ++ L R+ Q D EL R
Sbjct: 1763 ASGKSAL-LDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1821
Query: 603 -QQLENSRIKLKR 614
Q+ +N+R +L+R
Sbjct: 1822 AQKSDNARQQLER 1834
Score = 58.8 bits (136), Expect = 5e-08
Identities = 105/495 (21%), Positives = 198/495 (40%), Gaps = 62/495 (12%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E +D +EK +A ++ LEA + Q +++ DM++L+ + + V
Sbjct: 1511 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH 1570
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-----DWQTQSK 286
L+K + + +Q +++ QLE+ E Q LE + K D QT+ +
Sbjct: 1571 ELEK---SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE 1627
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++ + + +E+ +ER R A+ +K +E + L +++EA + E+ +
Sbjct: 1628 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1687
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDA---LESALGXXXXXXXXXXXXXXXXXH 402
KL + + + ARA E +++ L+S H
Sbjct: 1688 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 1747
Query: 403 LTEEVATLKYE-RDKATGKL-----------------NDLTTVRKNQESLIHRLQKRLLL 444
+E L E + A+GK +L + N E L R +K L
Sbjct: 1748 AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQ 1807
Query: 445 V-------------TRERDSYRQQLDCYEKELTVTLCGEEGA------GSVALLSARVQQ 485
V ++ D+ RQQL+ KEL L EGA +++ L A++ Q
Sbjct: 1808 VDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ 1867
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ A + A +K + ++ + E RR + + Q + A ++
Sbjct: 1868 LEEQLEQ-----EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMK 1922
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALREGGAQADPEEL 598
++ Q + A +++++ +EL+ A E E+ LK LR GG +
Sbjct: 1923 QLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSR 1982
Query: 599 QQMRQ-QLENSRIKL 612
RQ LE + ++L
Sbjct: 1983 SGRRQLHLEGASLEL 1997
Score = 56.8 bits (131), Expect = 2e-07
Identities = 88/375 (23%), Positives = 160/375 (42%), Gaps = 36/375 (9%)
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
Q T+ + +L+ ++ E +V K ++E E + + Q + L + E E+
Sbjct: 888 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA- 946
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWM 361
A E R A K LEE +H L SRV E Q +Q E + + + +E QL+
Sbjct: 947 EAEEMRARLA-AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 1005
Query: 362 SAARAHGVESAGA---LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
A + +E A ++ E L + E + L E +KA
Sbjct: 1006 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA- 1064
Query: 419 GKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL---TVTLCGE--EGA 473
+L +R QE +I L++RL ++ + RQ+L+ +++L T L + E
Sbjct: 1065 ---KNLAKIRNKQEVMISDLEERL----KKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1117
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHS----KALESLRNEVTRWREEAEGARRD 529
+ L ++ + E+ LQG L D H K + L+ ++ +E+ E +
Sbjct: 1118 AQIDELKLQLAKKEEELQG--ALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1175
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG 589
K Q+ L+ LE + +T++ + AA+ + + +E +E+ +LK AL E
Sbjct: 1176 RNKAEKQKRDLSEELEAL--KTELEDTLDTTAAQQELRTKRE-----QEVAELKKALEE- 1227
Query: 590 GAQADPEELQQMRQQ 604
+ ++Q MRQ+
Sbjct: 1228 ETKNHEAQIQDMRQR 1242
Score = 46.4 bits (105), Expect = 3e-04
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 24/279 (8%)
Query: 93 KRLKIDLIAAKAQI---TKLESRVNHQ----HTIRKEMQILFEEEKAS---LIEQHKRDE 142
K+++IDL +AQI K V Q K+ Q EE +AS + Q K E
Sbjct: 1662 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1721
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN 202
+ + +E + A++ +D A+ + D K +L EA
Sbjct: 1722 KKLKSLE-AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EAR 1779
Query: 203 VSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
++ ++++ E + +M+ L +V+ L EL + S A++ + QLE+QN
Sbjct: 1780 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN--- 1836
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+++ +KL+ELE S K T S K + +LE+++ + A ER+ + + +
Sbjct: 1837 KELKAKLQELEGAVKS-KFKATISALEAK----IGQLEEQLEQ-EAKERAAANKLVRRTE 1890
Query: 321 -LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
L+E Q+ + ++ +A ++ ++ QLE
Sbjct: 1891 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 1929
Score = 41.1 bits (92), Expect = 0.011
Identities = 91/502 (18%), Positives = 189/502 (37%), Gaps = 40/502 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRV---NHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
++L+++ + A+A+I K+E + Q++ + + L E+ A Q +E ++
Sbjct: 1009 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLA 1068
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ K ++L +K K L + DL+D++ E +
Sbjct: 1069 KIRNKQEVMISDLEERLKKEEKTRQEL----EKAKRKLDGETTDLQDQIAELQAQIDELK 1124
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++ K +EL AL E L Q +L+ E + + + +
Sbjct: 1125 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1184
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L E ++ K + + AQ+ L + E+EV L+ ++L + N E Q+
Sbjct: 1185 DLSEELEALKTELEDTLDTTAAQQEL--RTKREQEVAELK---KALEEETKNH---EAQI 1236
Query: 327 HQLTSR-VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
+ R AL+ + +L +AK ++ LE E A ++ L+
Sbjct: 1237 QDMRQRHATALEELSEQLEQAK----RFKANLEKNKQGLETDNKELACEVK-VLQQVKAE 1291
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYE-RDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
E L+ E +KA+ N+L N +L+ +K+ +
Sbjct: 1292 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL----DNVSTLLEEAEKKGIK 1347
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA 504
++ S QL ++ L +E LS+R++QLE+ ++
Sbjct: 1348 FAKDAASLESQLQDTQELL------QEETRQKLNLSSRIRQLEEEKNSLQE-----QQEE 1396
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEA 564
+A ++L +V + + ++ V + L + +++ + L A A
Sbjct: 1397 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1456
Query: 565 QKQISKELEAAQEEIKKLKVAL 586
++ K Q+E+ L V L
Sbjct: 1457 YDKLEKTKNRLQQELDDLTVDL 1478
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 63.3 bits (147), Expect = 2e-09
Identities = 99/466 (21%), Positives = 200/466 (42%), Gaps = 30/466 (6%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
+ N+ + K L A K +L QI DLK+K LEA + + ++ + D+ + L L
Sbjct: 1111 QMNSKVENEKGLVAQLQKTVKELQTQIKDLKEK-LEAERTTRAKMERERADLTQDLADLN 1169
Query: 225 GAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
EV ++ T + E + +L +E+ F+ ++ LK+ + + + Q
Sbjct: 1170 ERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQV 1229
Query: 284 QS--KTAQKRLCNMAELEKEVTRL--RANERSLRDAICNKL--LLEEQVHQLTSRVEALQ 337
++ + QK + ++L+ EV L R + + A KL L EE++H+ T++++ +
Sbjct: 1230 ENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVT 1289
Query: 338 PVQLELHEAKVKLSSVESQ----LESWMSAARAHGVESAGALRDALESALGXXXXXXXXX 393
+ +L K KL S + LE + E + R +E G
Sbjct: 1290 QLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQ-IEDLRGQLEKETKSQ 1348
Query: 394 XXXXXXXXHLTEEVATLK--YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
+ L+ YE ++ T + N E + R++ ++ R D
Sbjct: 1349 SALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTED- 1407
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
L+ +KEL + L +E A ++ + +AR LE++ + + D + + S
Sbjct: 1408 ----LEDAKKELAIRL--QEAAEAMGVANARNASLERARHQLQ--LELGDALSDLGKVRS 1459
Query: 512 LRNEVTRWREEAEGARRD-VTKLRTQRDLLTASLERI-GPQTKVLHLTN--NPAAEAQKQ 567
+ + + ++ A D K + LL AS + + T++L L N + Q+
Sbjct: 1460 AAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQET 1519
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ +E + QEEI L +REG + E++++++ +E + +++
Sbjct: 1520 LRRENKNLQEEISNLTNQVREG--TKNLTEMEKVKKLIEEEKTEVQ 1563
Score = 62.5 bits (145), Expect = 4e-09
Identities = 114/515 (22%), Positives = 215/515 (41%), Gaps = 62/515 (12%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L+ K E + Q T+R+E + L +EE ++L Q + + +++ME
Sbjct: 1495 EVQALSTELLKLK---NTYEESIVGQETLRRENKNL-QEEISNLTNQVREGTKNLTEMEK 1550
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKD-LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
K E +E + L+ N E LH Q+ +LLEA + ++
Sbjct: 1551 VKKLIEEE----KTEVQVTLEETEGALERN---ESKILHFQL-----ELLEAKAELERKL 1598
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKL 268
SE ++++ + Q ++ L+ L + + T+LK ++E+ E + Q++
Sbjct: 1599 SEKDEEIENFRRK---QQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCAN 1655
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
+++ S Q Q K Q +L + +L ++ A + ++L + +
Sbjct: 1656 RQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQE 1715
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
T R L + EL EA +++ +Q S +S + + A ++A E +
Sbjct: 1716 QTERGRRLS--EEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA-EEVVQECQN 1772
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+L+EE LK ++D + L R+N E I LQKRL
Sbjct: 1773 AEEKAKKAAIEAANLSEE---LKKKQDT----IAHLERTRENMEQTITDLQKRLA----- 1820
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
E E + L G + L +RV++LE L+G ++ + + ++
Sbjct: 1821 -----------EAE-QMALMGSR--KQIQKLESRVRELEGELEG--EIRRSAEAQRGARR 1864
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI 568
LE E+T +AE ++++++++TQ D L ++ Q +V N K+
Sbjct: 1865 LERCIKELT---YQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQ 1921
Query: 569 SKEL-------EAAQEEIKKLKVALREGGAQADPE 596
EL E A+ ++ KLK+ RE G + E
Sbjct: 1922 QHELNEVKERAEVAESQVNKLKIKAREFGKKVQEE 1956
Score = 54.8 bits (126), Expect = 9e-07
Identities = 91/397 (22%), Positives = 163/397 (41%), Gaps = 53/397 (13%)
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE----LEK 300
E+C QL+ LEK F+ +++ +K L E++ D Q + Q+ L N+ E L K
Sbjct: 876 EECAQLQKALEKSEFQREELKAKQVSLTQEKN---DLILQLQAEQETLANVEEQCEWLIK 932
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS--VESQLE 358
+L A + L + + + EE +LT+R L+ EL + L + V+S+ E
Sbjct: 933 SKIQLEARVKELSERVEEE---EEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKE 989
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE------VATLKY 412
+ + + + S L H+ EE A LK
Sbjct: 990 KRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKL 1049
Query: 413 ER--DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E+ D+ G L R N E +H+L+ L L R+S + L+ ++ L L +
Sbjct: 1050 EQQVDELEGALEQERKARMNCERELHKLEGNLKL---NRES-MENLESSQRHLAEELRKK 1105
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
E + Q+ ++ + L+A K ++ L+ ++ +E+ E R
Sbjct: 1106 E---------LELSQMNSKVENEKGLVA-----QLQKTVKELQTQIKDLKEKLEAERTTR 1151
Query: 531 TKLRTQRDLLTASL----ERI----GPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
K+ +R LT L ER+ G L +T + QK + +++E A +
Sbjct: 1152 AKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKIQK-LHRDMEEATLHFETT 1210
Query: 583 KVALREGGA------QADPEELQQMRQQLENSRIKLK 613
+L++ A + E LQQ++Q+LE + L+
Sbjct: 1211 SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQ 1247
Score = 47.6 bits (108), Expect = 1e-04
Identities = 108/540 (20%), Positives = 213/540 (39%), Gaps = 47/540 (8%)
Query: 104 AQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXK 163
AQ+ K + Q K Q+ +EK LI Q + ++ ++++E+ K
Sbjct: 879 AQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEE----QCEWLIKSK 934
Query: 164 DEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD---QISEMKKDMDELL 220
+ KE + ++ ++L + L+D+ E D + + +K+
Sbjct: 935 IQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTE 994
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ--LEKQNFEFQQVTSKLK---ELEYER 275
++ EVE L +++ K +RA + Q +Q L+ + E ++++S K +LE +
Sbjct: 995 HKVKNLTEEVEFLNEDISK-LNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQV 1053
Query: 276 DSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH-------Q 328
D + Q + A+ C EL K L+ N S+ + ++ L E++ Q
Sbjct: 1054 DELEGALEQERKARMN-CE-RELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQ 1111
Query: 329 LTSRVE-----------ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD 377
+ S+VE ++ +Q ++ + K KL + E + M RA + L +
Sbjct: 1112 MNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEA-ERTTRAKMERERADLTQDLADLNE 1170
Query: 378 ALESALGXXXX--XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
LE G H E ATL +E A+ K ++ + E +
Sbjct: 1171 RLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAE-LEGQV 1229
Query: 436 HRLQKRLLLVTRERDSYRQQL-DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYR 494
LQ+ + +++ + ++ D + +T L R+ + L
Sbjct: 1230 ENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVT 1289
Query: 495 DLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVL 554
L A+D A L S E R EE E + +L ++ T +E + Q +
Sbjct: 1290 QL--ANDLAAQKTKLWSESGEFLRRLEEKEAL---INQLSREKSNFTRQIEDLRGQLEKE 1344
Query: 555 HLTNNPAAEAQKQISKE---LEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
+ + A A ++ ++ L EE +++K L ++ + E+ Q R + EN+ I+
Sbjct: 1345 TKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVN-AEMVQWRMKYENNVIQ 1403
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 62.9 bits (146), Expect = 3e-09
Identities = 107/538 (19%), Positives = 225/538 (41%), Gaps = 39/538 (7%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L+ +I LE+ +N +H +++ + FE+ K +EQHK E+ + +E
Sbjct: 284 LEQELMEKNEKIRSLETNINTEH---EKICLAFEKAKKIHLEQHKEMEKQIERLE---AQ 337
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKK 214
K++ T + +D+ L + + + K ++ + N+ + + ++
Sbjct: 338 LEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKGEMKKENMKKDEALKALQN 396
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSKLKELEY 273
+ E + S +E+ K+ELV ++ E + + QL+K++ ++V KEL+
Sbjct: 397 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKS---EEVYCLQKELKI 453
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
+ S ++ Q+ Q L ++ ++ T +R E L D + LE+QV +L
Sbjct: 454 KNHSLQETSEQNVILQHTLQQQQQMLQQET-IRNGE--LED---TQTKLEKQVSKLE--- 504
Query: 334 EALQPVQLELHEAKVKLSSVESQLESWMSAA---RAHGVESAGALRDA---LESALGXXX 387
Q +Q + + KL +E + ES A R +E G R ++
Sbjct: 505 ---QELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELS 561
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
+ + L D+ +L T K E L H + L +
Sbjct: 562 KMEKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 621
Query: 448 ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK 507
+R+ +L EL TL + V L A++ LE+ +DL A +
Sbjct: 622 KREVLETELQNAHGELKSTLRQLQELRDV-LQKAQL-SLEEKYTTIKDLTA--ELRECKM 677
Query: 508 ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHL--TNNPAAE 563
+E + E+ + + ++ + Q L ++ E G + K++ L T +
Sbjct: 678 EIEDEKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL 737
Query: 564 AQKQISKELEAAQEEIKKLKVALREGG--AQADPEELQQMRQQLENSRIKLKRYSIVL 619
K+ +K++E+ ++++ K LRE + +E+ Q+++++E ++ ++K V+
Sbjct: 738 ELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 795
Score = 58.8 bits (136), Expect = 5e-08
Identities = 110/502 (21%), Positives = 205/502 (40%), Gaps = 45/502 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q++KLE + Q E EE+ S + + V ++ K+
Sbjct: 499 QVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKE 558
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E + KE LK D E +H + L D +L+ + ++ + K++++L + E
Sbjct: 559 ELSKMEKEIMHLKR--DGENKAMH--FSQL-DMILDQTKTELEKKTNAVKELEKLQHSTE 613
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYKDWQT 283
+E L+K V +T +LK+ L +Q E + V K + LE + + KD
Sbjct: 614 TELTEA--LQKREVLETELQNAHGELKSTL-RQLQELRDVLQKAQLSLEEKYTTIKD--- 667
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
TA+ R C M E+E E L +++L++ L+++ Q+T ++ + E+
Sbjct: 668 --LTAELRECKM-EIEDEKQELLEMDQALKE---RNWELKQRAAQVTHLDMTIREHRGEM 721
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+ +KL + E + +ES L D L++A
Sbjct: 722 EQKIIKLEGTLEKSELELKECNKQ-IES---LNDKLQNA-------KEQLREKEFIMLQN 770
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
+E++ LK E ++ ++ ++ +V K QE I K + + ++ R+Q+ EL
Sbjct: 771 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQNSHTEL 830
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
E +++L L+ + L D H + A E ++V EA
Sbjct: 831 A------EARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEA 884
Query: 524 EGARRDVTKLRTQRDLLTAS--LERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ ++ KL + + L + +E I Q H +A++QK ++L E+++K
Sbjct: 885 R-MQAEIKKLSAEVESLKEAYHMEMISHQEN--HAKWKISADSQKSSVQQL---NEQLEK 938
Query: 582 LKVALREGGAQADPEELQQMRQ 603
K+ L E AQ L Q Q
Sbjct: 939 AKLELEE--AQDTVSNLHQQVQ 958
Score = 58.0 bits (134), Expect = 9e-08
Identities = 117/522 (22%), Positives = 228/522 (43%), Gaps = 58/522 (11%)
Query: 110 ESRVNHQHTIRKEMQILFEE--EKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
E V QHT++++ Q+L +E L + + E+ VS +E K +
Sbjct: 463 EQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQ---------KQRES 513
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGA 226
+A K K +EK + ADLK K++E + + ++K +MD+ + L
Sbjct: 514 SAEKLRKM------EEKCESAAHEADLKRQKVIELTGTAR----QVKIEMDQYKEELSKM 563
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ E+ LK++ ++A +QL L++ E ++ T+ +KELE + S + T++
Sbjct: 564 EKEIMHLKRD---GENKAMHFSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEA- 619
Query: 287 TAQKRLCNMAELEKEVTRLRANERSL---RDAICN-KLLLEEQVHQLTSRVEALQPVQLE 342
QKR EL+ L++ R L RD + +L LEE+ + L+ ++E
Sbjct: 620 -LQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKME 678
Query: 343 LHEAKVKLSSVESQLE--SWMSAARAHGVESAG-ALRDALESALGXXXXXXXXXXXXXXX 399
+ + K +L ++ L+ +W RA V +R+
Sbjct: 679 IEDEKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 738
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
+++ +L + A +L + + E I +L+K + T++R + +
Sbjct: 739 LKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIER-TQQRMKEMESVMKE 797
Query: 460 EKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRW 519
+++ T C E L R +Q++ S + +L A H +A + E+ R
Sbjct: 798 QEQYIATQCKEAIDLGQKLRLTR-EQVQNS---HTELAEAR--HQQVQA----QREIERL 847
Query: 520 REEAEGARRDVTKLRTQRDLLTASL-ERIGP-QTKVLHLTNNPAAEAQKQISKELEAAQE 577
E E D+ +L ++D L E +G + + HL AE +K +S E+E+ +E
Sbjct: 848 SSELE----DMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKK-LSAEVESLKE 902
Query: 578 EIKKLKVALREGGAQ----ADPEE--LQQMRQQLENSRIKLK 613
++ +E A+ AD ++ +QQ+ +QLE ++++L+
Sbjct: 903 AYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE 944
Score = 51.2 bits (117), Expect = 1e-05
Identities = 77/424 (18%), Positives = 168/424 (39%), Gaps = 19/424 (4%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK 235
+ ++KE+ L I +L+ KL++ N D M + E + K
Sbjct: 189 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 248
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE----RDSYKDWQTQSKTAQKR 291
+ T + Q L+ QLE++ + + +K ELE E + + +T T ++
Sbjct: 249 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEK 308
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+C E K++ L ++ + + LE++ Q + + + +Q ++ + L
Sbjct: 309 ICLAFEKAKKI-HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE 367
Query: 352 SVESQLESWMSAARAHGVESAGALR----DALESALGXXXXXXXXXXXXXXXXXHLTE-E 406
S++ L + ++ AL+ E + HL + E
Sbjct: 368 SLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 427
Query: 407 VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
K+E+ + K ++ ++K + H LQ+ + + +QQ ++E T
Sbjct: 428 GNKEKFEK-QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQE---T 483
Query: 467 LCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGA 526
+ E + L +V +LE+ LQ R+ +A + ES +E R++
Sbjct: 484 IRNGELEDTQTKLEKQVSKLEQELQKQRE-SSAEKLRKMEEKCESAAHEADLKRQKVIEL 542
Query: 527 RRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ--KQISKELEAAQEEIKKLKV 584
+++ + D L ++ + +++HL + +A Q+ L+ + E++K
Sbjct: 543 TGTARQVKIEMDQYKEELSKM--EKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTN 600
Query: 585 ALRE 588
A++E
Sbjct: 601 AVKE 604
Score = 32.3 bits (70), Expect = 5.3
Identities = 58/355 (16%), Positives = 141/355 (39%), Gaps = 14/355 (3%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L+ +L A ++ ++ + ++ Q+ EE+ ++ + ++ED
Sbjct: 626 LETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQE 685
Query: 155 XXXXXXXXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
K+ E A + L + + ++ ++I L+ L ++ + ++ E
Sbjct: 686 LLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSEL----ELKE 741
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
K ++ L L+ A+ ++ +KE + ++ +QLK ++E+ +++ S +KE
Sbjct: 742 CNKQIESLNDKLQNAKEQLR--EKEFI-MLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 798
Query: 272 E-YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE-EQVHQL 329
E Y K+ + + + E+ R + + I +L E E + QL
Sbjct: 799 EQYIATQCKEAIDLGQKLRLTREQVQNSHTELAEARHQQVQAQREI-ERLSSELEDMKQL 857
Query: 330 TSRVEAL-QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ +A + EL +KV+ + +E+++++ + A A + S
Sbjct: 858 SKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAK 917
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L E++ K E ++A +++L +++ +I + LL
Sbjct: 918 WKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALL 972
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 62.5 bits (145), Expect = 4e-09
Identities = 94/439 (21%), Positives = 189/439 (43%), Gaps = 40/439 (9%)
Query: 171 KEHKDLKANWD---KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDEL---LQALE 224
+ +K LKA + K D+ K + +L+ ++ + + Q+ EMK ++EL LQA E
Sbjct: 30 RTNKMLKAEMEDLVSSKDDVGKNVHELE----KSKRALETQMEEMKTQLEELEDELQATE 85
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
A+ +E+ + L Q R Q +N+ EK+ +Q+ +L E E E + + +
Sbjct: 86 DAKLRLEVNMQALKGQFERDLQARDEQNE-EKR----RQLQRQLHEYETELEDERKQRAL 140
Query: 285 SKTAQKRL-CNMAELEKEV-TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ A+K+L ++ +LE + + ++ E +++ + +++ +L + +
Sbjct: 141 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFAT 200
Query: 343 LHEAKVKLSSVESQLESWMS--AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
E + K S+E+ L AA + A ++ L L
Sbjct: 201 AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR-- 258
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL---VTRERDSYRQQLD 457
L +A L+ E ++ G + ++ + +L L ++ +S RQQL+
Sbjct: 259 -RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLE 317
Query: 458 CYEKELTVTLCGEEGA------GSVALLSARVQQLEKSL-QGYRDLIAAHDP-HAHSKAL 509
KEL L EGA ++A L A++ QLE+ + Q R+ AA K L
Sbjct: 318 RQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 377
Query: 510 ESL-------RNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAA 562
+ + R +++E+AE V +L+ Q + +RI + L + A
Sbjct: 378 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 437
Query: 563 EAQKQISKELEAAQEEIKK 581
E+ + + +E+ A + ++++
Sbjct: 438 ESNEAMGREVNALKSKLRR 456
Score = 52.8 bits (121), Expect = 3e-06
Identities = 102/437 (23%), Positives = 188/437 (43%), Gaps = 49/437 (11%)
Query: 200 EANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQN 258
EA K+ + + + ++E L+A E + +MLK E+ S + + ++LEK
Sbjct: 1 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 60
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTR-LRANERSLRDAI 316
+ + ++++E++ + + +D ++ A+ RL NM L+ + R L+A + +
Sbjct: 61 ---RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE-- 115
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
+ L+ Q+H+ + +E + + AK KL LE +A E+ LR
Sbjct: 116 -KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 174
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK--ATGKLNDLTTVRKNQESL 434
L++ + E+ + RD+ AT K N+ K+ E+
Sbjct: 175 -KLQAQM-----------------KDFQRELEDARASRDEIFATAKENEKKA--KSLEAD 214
Query: 435 IHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEG-AGSVALLSARVQQLEKSL--- 490
+ +LQ+ L R R + + +EL +L G L AR+ QLE+ L
Sbjct: 215 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 274
Query: 491 QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQ 550
QG + ++ A +A E L NE+ R A+ +L Q L + L +
Sbjct: 275 QGNMEAMSDRVRKATQQA-EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 333
Query: 551 TKVLHLTNNPAAEAQ--------KQISKELEAAQEEIKKLKVALREGGAQADPEE--LQQ 600
K + A EA+ +Q ++E +AA + +K+ L+E Q + E +Q
Sbjct: 334 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 393
Query: 601 MRQQLE--NSRIK-LKR 614
++Q E N+R+K LKR
Sbjct: 394 YKEQAEKGNARVKQLKR 410
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/249 (22%), Positives = 115/249 (46%), Gaps = 27/249 (10%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
K+ Q E+ +AS RDE + E+ + + + AA E +A
Sbjct: 181 KDFQRELEDARAS------RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA-- 232
Query: 181 DKEKTDLHKQIAD-------LKD--KLLEANVSN-KDQISEMKKDMDELLQALEGAQSEV 230
D EK +L +++A L+D + LEA ++ ++++ E + +M+ + + A +
Sbjct: 233 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 292
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQK 290
E L EL + S A++ + QLE+QN +++ SKL E+E S +++ +
Sbjct: 293 EQLSNELATERSTAQKNESARQQLERQN---KELRSKLHEMEGAVKS--KFKSTIAALEA 347
Query: 291 RLCNMAE-LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVK 349
++ + E +E+E +A +SL+ L+E + Q+ + + + + + +
Sbjct: 348 KIAQLEEQVEQEAREKQAATKSLKQ---KDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 404
Query: 350 LSSVESQLE 358
+ ++ QLE
Sbjct: 405 VKQLKRQLE 413
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 62.1 bits (144), Expect = 6e-09
Identities = 109/522 (20%), Positives = 226/522 (43%), Gaps = 38/522 (7%)
Query: 102 AKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXX 161
A+ ++ KL++R + IRK+ L E E+ L E+H+ + + +E
Sbjct: 669 AERELEKLQNREDSSEGIRKK---LVEAEE--LEEKHREAQVSAQHLEVHLKQKEQHYEE 723
Query: 162 XKDEFNTAAKEHKDLKANWDKEKT-DLHKQIADLKDKLL---EANVSNKD-QISEMKKDM 216
+ K KDL E H++ A K K+L +A ++ D +I +++ +
Sbjct: 724 KIKVLDNQIK--KDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRI 781
Query: 217 DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
EL +A + A + ++ + Q + Q K LE Q + + KL+E + E+
Sbjct: 782 VELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEE-QLEKI 840
Query: 277 SYKDWQTQSKTAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
S++D +++ + + LE E +L +R L + +L L+E+ QLT+ A
Sbjct: 841 SHQDHSDKNRLLELETRLREVSLEHEEQKLEL-KRQLTEL---QLSLQERESQLTALQAA 896
Query: 336 LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXX 395
++ +L +AK +L ++ E + A AH E DAL ++
Sbjct: 897 RAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKF-DALRNSCTVITDLEEQLNQ 955
Query: 396 XXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQ 455
L + L + D+A+G +++ +R + L + +R + +T S +Q
Sbjct: 956 LTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLT----SQKQT 1011
Query: 456 LDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNE 515
++ + T+ EE + L+ + + E+ + +R ++ + E R
Sbjct: 1012 MEALKTTCTML---EEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 1068
Query: 516 VTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAA 575
T E+ AR D ++ R ++ +++ + K L A + QK ++ L
Sbjct: 1069 DT---EKQSRARAD-QRITESRQVVELAVK----EHKAEILALQQALKEQKLKAESLSDK 1120
Query: 576 QEEIKKLKVALREGGAQADPEELQ---QMRQQLENSRIKLKR 614
+++K K A+ E A++ ++L+ +++Q+L + KL++
Sbjct: 1121 LNDLEK-KHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQ 1161
Score = 37.5 bits (83), Expect = 0.14
Identities = 55/241 (22%), Positives = 97/241 (40%), Gaps = 20/241 (8%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEF 166
T+ +SR I + Q++ E A +++HK + A ++ D+
Sbjct: 1070 TEKQSRARADQRITESRQVV---ELA--VKEHKAEILA---LQQALKEQKLKAESLSDKL 1121
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N K+H L+ N + L + +LK +LLE + Q+ K + L Q L+ A
Sbjct: 1122 NDLEKKHAMLEMNARSLQQKLETE-RELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEA 1180
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
++LK E + E L + EK E ++ + K +++ + + K
Sbjct: 1181 LDRADLLKTERSDLEYQLENIQVLYSH-EKVKME-GTISQQTKLIDFLQAKMDQPAKKKK 1238
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEA 346
R L +V L+ NE KL LE++ + EALQ ++EL A
Sbjct: 1239 GLFSRRKEDPALPTQVP-LQYNEL--------KLALEKEKARCAELEEALQKTRIELRSA 1289
Query: 347 K 347
+
Sbjct: 1290 R 1290
Score = 35.9 bits (79), Expect = 0.43
Identities = 112/538 (20%), Positives = 201/538 (37%), Gaps = 39/538 (7%)
Query: 79 SGNGTTAPPSPWETKRL--KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIE 136
SG + A S E K L +L ++ + K+E + H E++ + +++ L
Sbjct: 436 SGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVEL-- 493
Query: 137 QHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKD 196
K E S +E K A E + DK LH I +
Sbjct: 494 --KASETQRSLLEQDLATYITECSSLKRSLEQARME---VSQEDDKALQLLH-DIREQSR 547
Query: 197 KLLEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ----CTQLK 251
KL E + Q+ EM+ M++L + L A+ ++ + EL + AE+ T+ +
Sbjct: 548 KLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQ 607
Query: 252 NQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS 311
++L K + + + +LE + Q + + Q++L + E T L N R
Sbjct: 608 HKLLKAKDQGKPEVGEYAKLE---KINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQ 664
Query: 312 LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ-LESWMSAARAHGVE 370
++ + L + Q + +S + V+ E E K + + V +Q LE + H E
Sbjct: 665 AKER-AERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEE 723
Query: 371 SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKN 430
L + ++ L + ++ K + K+ L R
Sbjct: 724 KIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQ-RIV 782
Query: 431 QESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL 490
+ S ++L L T+ ++++ ++ L E AG L A+ ++LE+ L
Sbjct: 783 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYL--ETQAGK---LEAQNRKLEEQL 837
Query: 491 QGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQ 550
+ +H H+ L L TR RE + +L+ Q L SL+ Q
Sbjct: 838 EK-----ISHQDHSDKNRLLELE---TRLREVSLEHEEQKLELKRQLTELQLSLQERESQ 889
Query: 551 TKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
L +Q ELE E ++ AL A +E+Q+ L NS
Sbjct: 890 LTALQAARAALESQLRQAKTELEETTAEAEEEIQAL-----TAHRDEIQRKFDALRNS 942
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 62.1 bits (144), Expect = 6e-09
Identities = 109/522 (20%), Positives = 226/522 (43%), Gaps = 38/522 (7%)
Query: 102 AKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXX 161
A+ ++ KL++R + IRK+ L E E+ L E+H+ + + +E
Sbjct: 217 AERELEKLQNREDSSEGIRKK---LVEAEE--LEEKHREAQVSAQHLEVHLKQKEQHYEE 271
Query: 162 XKDEFNTAAKEHKDLKANWDKEKT-DLHKQIADLKDKLL---EANVSNKD-QISEMKKDM 216
+ K KDL E H++ A K K+L +A ++ D +I +++ +
Sbjct: 272 KIKVLDNQIK--KDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRI 329
Query: 217 DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
EL +A + A + ++ + Q + Q K LE Q + + KL+E + E+
Sbjct: 330 VELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEE-QLEKI 388
Query: 277 SYKDWQTQSKTAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
S++D +++ + + LE E +L +R L + +L L+E+ QLT+ A
Sbjct: 389 SHQDHSDKNRLLELETRLREVSLEHEEQKLEL-KRQLTEL---QLSLQERESQLTALQAA 444
Query: 336 LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXX 395
++ +L +AK +L ++ E + A AH E DAL ++
Sbjct: 445 RAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKF-DALRNSCTVITDLEEQLNQ 503
Query: 396 XXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQ 455
L + L + D+A+G +++ +R + L + +R + +T S +Q
Sbjct: 504 LTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLT----SQKQT 559
Query: 456 LDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNE 515
++ + T+ EE + L+ + + E+ + +R ++ + E R
Sbjct: 560 MEALKTTCTML---EEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRML 616
Query: 516 VTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAA 575
T E+ AR D ++ R ++ +++ + K L A + QK ++ L
Sbjct: 617 DT---EKQSRARAD-QRITESRQVVELAVK----EHKAEILALQQALKEQKLKAESLSDK 668
Query: 576 QEEIKKLKVALREGGAQADPEELQ---QMRQQLENSRIKLKR 614
+++K K A+ E A++ ++L+ +++Q+L + KL++
Sbjct: 669 LNDLEK-KHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQ 709
Score = 37.1 bits (82), Expect = 0.18
Identities = 43/221 (19%), Positives = 88/221 (39%), Gaps = 17/221 (7%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEF 166
T+ +SR I + Q++ E A +++HK + A ++ D+
Sbjct: 618 TEKQSRARADQRITESRQVV---ELA--VKEHKAEILA---LQQALKEQKLKAESLSDKL 669
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N K+H L+ N + L + +LK +LLE + Q+ K + L Q L+ A
Sbjct: 670 NDLEKKHAMLEMNARSLQQKLETE-RELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEA 728
Query: 227 QSEVEMLKKELVK--------QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY 278
++LK E Q + + +++ + +Q + +K+ + ++
Sbjct: 729 LDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKVP 788
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
+ +K AELE+ + + R RS R+ ++
Sbjct: 789 LQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHR 829
Score = 33.9 bits (74), Expect = 1.7
Identities = 104/508 (20%), Positives = 188/508 (37%), Gaps = 37/508 (7%)
Query: 107 TKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEF 166
T +E + H E++ + +++ L K E S +E K
Sbjct: 14 TMMEQEMTRLHRRVSEVEAVLSQKEVEL----KASETQRSLLEQDLATYITECSSLKRSL 69
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEG 225
A E + DK LH I + KL E + Q+ EM+ M++L + L
Sbjct: 70 EQARME---VSQEDDKALQLLH-DIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVS 125
Query: 226 AQSEVEMLKKELVKQTSRAEQ----CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
A+ ++ + EL + AE+ T+ +++L K + + + +LE +
Sbjct: 126 ARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLE---KINAEQ 182
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQL 341
Q + + Q++L + E T L N R ++ + L + Q + +S + V+
Sbjct: 183 QLKIQELQEKLEKAVKASTEATELLQNIRQAKER-AERELEKLQNREDSSEGIRKKLVEA 241
Query: 342 ELHEAKVKLSSVESQ-LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
E E K + + V +Q LE + H E L + ++ L
Sbjct: 242 EELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEA 301
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
+ ++ K + K+ L R + S ++L L T+ ++++
Sbjct: 302 HEKGKILSEQKAMINAMDSKIRSLEQ-RIVELSEANKLAANSSLFTQRNMKAQEEMISEL 360
Query: 461 KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWR 520
++ L E AG L A+ ++LE+ L+ +H H+ L L TR R
Sbjct: 361 RQQKFYL--ETQAGK---LEAQNRKLEEQLEK-----ISHQDHSDKNRLLELE---TRLR 407
Query: 521 EEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIK 580
E + +L+ Q L SL+ Q L +Q ELE E +
Sbjct: 408 EVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAE 467
Query: 581 KLKVALREGGAQADPEELQQMRQQLENS 608
+ AL A +E+Q+ L NS
Sbjct: 468 EEIQAL-----TAHRDEIQRKFDALRNS 490
Score = 33.5 bits (73), Expect = 2.3
Identities = 41/181 (22%), Positives = 81/181 (44%), Gaps = 13/181 (7%)
Query: 169 AAKEHKDLKANWDKEK-TDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE-LLQALEGA 226
A KE K LKA +K DL K K +LE N + Q E ++++ + LL+
Sbjct: 654 ALKEQK-LKAESLSDKLNDLEK-----KHAMLEMNARSLQQKLETERELKQRLLEEQAKL 707
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
Q ++++ K + + T ++ + L+ + + + ++ L Y + K T S+
Sbjct: 708 QQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVL-YSHEKVKMEGTISQ 766
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEA 346
Q +L + + + + + + + KL LE++ + EALQ ++EL A
Sbjct: 767 --QTKLIDFLQAKMDQPAKKKKVPLQYNEL--KLALEKEKARCAELEEALQKTRIELRSA 822
Query: 347 K 347
+
Sbjct: 823 R 823
>AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein.
Length = 690
Score = 60.9 bits (141), Expect = 1e-08
Identities = 120/553 (21%), Positives = 223/553 (40%), Gaps = 56/553 (10%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
K I E + N++ T ++ ++ + +E K ++ + ER++S+ ED
Sbjct: 117 KELIALQEDKHNYETTAKESLRRVLQE-KIEVVRKLSEVERSLSNTEDECTHLKEMNERT 175
Query: 163 KDE-------FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKD 215
++E +N A E KDL DK K KQ +++ K + +I EM++
Sbjct: 176 QEELRELANKYNGAVNEIKDLS---DKLKVAEGKQ-EEIQQKGQAEKKELQHKIDEMEEK 231
Query: 216 MDELLQALEGAQSEVEMLKKELVK-----QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
EL +E Q++ + + L + CT + +E Q V L +
Sbjct: 232 EQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLI--VEGHLTK 289
Query: 271 LEYERDSYKDWQTQSKTAQKRLCNMAELEK---EVTRLRANERSLRDAICNKLLLEEQVH 327
E K+ QT++K + EK + T + +E+ L + + LL++ +
Sbjct: 290 AVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQ 349
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
S +EA Q +Q L + ++ + + +A E A R+ +E +
Sbjct: 350 GAQSEIEAKQEIQ-HLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQ 408
Query: 388 XXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDL-------TTVRKNQESLIHRLQ 439
+L EE + + RD+ +++ V +++ I LQ
Sbjct: 409 VLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQ 468
Query: 440 KRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKS--LQGYRDLI 497
+ L V E + +R+ YEKE+T + + + QQ E++ LQG + +
Sbjct: 469 EELKKVRAELERWRKAASEYEKEIT----SLQNSFQLRCQQCEDQQREEATRLQGELEKL 524
Query: 498 A----AHDPHAHSKALES--LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT 551
A + HS E+ L +E+ R +E +++ +L + +L S + + Q
Sbjct: 525 RKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQV 584
Query: 552 ---KVLHLTNN-------PAAEAQ-KQISKELEAAQEEIK--KLKVALREGGAQADPEEL 598
K HL ++ AE Q K + KE E Q + KLK + E Q+ +EL
Sbjct: 585 GSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDEL 644
Query: 599 QQMRQQLENSRIK 611
+Q + L+ R K
Sbjct: 645 KQCKNNLKLLREK 657
Score = 45.2 bits (102), Expect = 7e-04
Identities = 90/419 (21%), Positives = 177/419 (42%), Gaps = 33/419 (7%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQ 263
++D++ + M LQA Q+E + L+KEL+ Q + T K L + E +
Sbjct: 88 DEDRLLSRLEVMGNQLQACSKNQTE-DSLRKELIALQEDKHNYETTAKESLRRVLQEKIE 146
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
V KL E+E + +D T K +R EL + + ++D + E
Sbjct: 147 VVRKLSEVERSLSNTEDECTHLKEMNER--TQEELRELANKYNGAVNEIKDLSDKLKVAE 204
Query: 324 EQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
+ ++ + +A + +Q ++ E + K +++++E+ + A E AL++ L S
Sbjct: 205 GKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEA-LQADNDFTNERLTALQEHLLSK 263
Query: 383 LG---XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT-GKLNDLTTVRKNQESLIHRL 438
G HLT+ V K ++ T K +D + ++L
Sbjct: 264 SGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFS------DTLSPSK 317
Query: 439 QKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDL 496
+K T D+ + D E V+L ++ G+ + + A+ +Q L K L ++L
Sbjct: 318 EKSSDDTT---DAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQEL 374
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL 556
A L++L EE + R V + Q +L A L+R+ T+ L
Sbjct: 375 --ARTSKQKCFELQAL------LEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLRE 426
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRY 615
+ + + EL +A++EI L A + ++ D ++ ++++L+ R +L+R+
Sbjct: 427 EKDSEITSTRD---ELLSARDEILLLHQAAAKVASERD-TDIASLQEELKKVRAELERW 481
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 60.5 bits (140), Expect = 2e-08
Identities = 117/532 (21%), Positives = 219/532 (41%), Gaps = 43/532 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME- 149
E +R + + + Q+ + RV+ T+ + + L + + +E+ ++D + E
Sbjct: 906 EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQ--LERLRQDMKVQKLKEQ 963
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKE-------KTDLHKQIADLKDKLLEAN 202
+ + E AA++H+D A +E K DL KQ+ DLK +L+ +
Sbjct: 964 ETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQD 1023
Query: 203 VSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ 262
S + E+++ + E Q Q E+E K L EQ +L E + Q
Sbjct: 1024 DSQRLVEQEVQEKLRET-QEYNRIQKELEREKASLTLSLMEKEQ--RLLVLQEADSIRQQ 1080
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL 322
++++ ++++ + K+ +AQ L EKE L A E L + + +
Sbjct: 1081 ELSALRQDMQEAQGEQKEL-----SAQMELLRQEVKEKEADFL-AQEAQLLEELEASHIT 1134
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
E+Q+ EA + QL+L +L S ESQLE+ + + A A +L SA
Sbjct: 1135 EQQLRASLWAQEA-KAAQLQL-----RLRSTESQLEALAAEQQPGNQAQAQAQLASLYSA 1188
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG--KLNDLTTVRKNQ--ESLIHRL 438
L V L+ +++ A K L T + S +H+L
Sbjct: 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1248
Query: 439 QKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA 498
+ L + RD R Q+ E+ LT T + + +Q L++ L ++ +
Sbjct: 1249 HQDLWKTQQTRDVLRDQVQKLEERLTDT------EAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 499 AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHL 556
+ +S E + T ++ R ++ ++ Q R+LL A+ E + Q V HL
Sbjct: 1303 KWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQ--VEHL 1360
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVA--LREGGAQADPEELQQMRQQLE 606
EA+ Q S +E+++ + A L+ +++ E Q +++Q E
Sbjct: 1361 -QAAVVEARAQAS-AAGILEEDLRTARSALKLKNEEVESERERAQALQEQGE 1410
Score = 52.0 bits (119), Expect = 6e-06
Identities = 107/570 (18%), Positives = 235/570 (41%), Gaps = 60/570 (10%)
Query: 88 SPWETKR--LKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDE 142
S WE K+ L+ +L+ + L+SR+ R E Q L + K +L Q + +
Sbjct: 1302 SKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQ 1361
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTA--AKEHKDLKANWDKEKTDLHKQIADLK---DK 197
AV + +++ TA A + K+ + ++E+ ++ +LK K
Sbjct: 1362 AAVVEAR----AQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 198 LLEANVS--------NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
L+ N++ ++++ ++ + EL + E ++ +E+L +L K+ + +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Query: 250 LKNQLEKQNFEFQQVTSKLKELEYE--------RDSYKDWQTQSKTAQKRLCNMAELEKE 301
+LEK + + ++E E + R+ KD +TQ + +L + + ++
Sbjct: 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQM 1537
Query: 302 VTRLRANERSLRDAI----CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ R + L+ + C L LEE H++ + + ++ ++ + +V L+ + L
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 358 ES-----WMSAARAHGVES-AGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
E +++ H +ES + L L+ HLT+++
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD 1657
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E ++ L R Q ++ +++ L RER ++L +++L + EE
Sbjct: 1658 QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERG---RELTT-QRQL-MQERAEE 1712
Query: 472 GAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
G G ++ ++ L+ + H H L+ L++++ + + + +
Sbjct: 1713 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHE--LQELKDQLEQQLQGLHRKVGETS 1770
Query: 532 KLRTQRD----LLTASLERIGPQTKV----LHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
L +QR+ +L L+ Q ++ L + A A Q +ELEA Q+E ++
Sbjct: 1771 LLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ-- 1828
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLK 613
+G + E+ ++ LE + + LK
Sbjct: 1829 ---AQGQEERVKEKADALQGALEQAHMTLK 1855
Score = 50.4 bits (115), Expect = 2e-05
Identities = 89/428 (20%), Positives = 178/428 (41%), Gaps = 31/428 (7%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQC-- 247
+++ L + L V Q+ +++++ + +E A+ L+ +L + R E
Sbjct: 600 KLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWE 659
Query: 248 --TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTR 304
T L+ QL+K ++ + L++++ E++ + ++S+ Q+ E L +E R
Sbjct: 660 KNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKR 719
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA 364
E L A+ K L + L R++A++ + +L E LSS + LES + A
Sbjct: 720 ---QEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEA 776
Query: 365 RAHG--VE-SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
+ +E + G L +++ L E + + ERD A +L
Sbjct: 777 QQQNSVIEVTKGQLEVQIQTV---TQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQL 833
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSA 481
++ + +L + V + R+ + ++ +++EL L E +
Sbjct: 834 --AQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRL 891
Query: 482 RVQQLE-KSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLL 540
+ QQ E +++Q R+ + AL ++ E E E T L+TQ++L
Sbjct: 892 KEQQTEMEAIQAQRE----EERTQAESALCQMQLET-----EKERVSLLETLLQTQKELA 942
Query: 541 TAS--LERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEEL 598
AS LER+ KV L E + +L+ AQ E+K+ R+ A E
Sbjct: 943 DASQQLERLRQDMKVQKLKEQ---ETTGILQTQLQEAQRELKEAARQHRDDLAALQEESS 999
Query: 599 QQMRQQLE 606
++ +++
Sbjct: 1000 SLLQDKMD 1007
Score = 49.6 bits (113), Expect = 3e-05
Identities = 104/457 (22%), Positives = 182/457 (39%), Gaps = 20/457 (4%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E T + ++K+ D++ +L + L LL + + + + E
Sbjct: 183 EVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGRE 242
Query: 225 GAQSEVEMLK-KELVKQT-SRAEQCTQLKNQLEKQNFEFQQVTSKLKEL-EYERDSYKDW 281
AQ + + K +EL K+ R+++ QLK+Q + + E Q ++L L + +D+
Sbjct: 243 PAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDY 302
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSL-RDAICNKLLLEEQVHQLTSRV--EALQP 338
+ K ++ + LE T L +E SL R+A KL L++ + +T + E
Sbjct: 303 EKMIKALRE---TVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNI 359
Query: 339 VQLELHEAKVKL-SSVESQLESWMSAARAHGVESA-GALRDALESALGXXXXXXXXXXXX 396
Q HE ++L SS+ SQ + + V S R A++
Sbjct: 360 AQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLL 419
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
EE L+ K TG+ + L + + + L K L+ + R+ RQQL
Sbjct: 420 QQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQL 479
Query: 457 DCYEKE---LTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKALESL 512
+ E+E L + G A QQ E L R+ + +K ESL
Sbjct: 480 EVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESL 539
Query: 513 RNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI---S 569
+E+ RE E + + LR ++ +TA+L R L + N + +
Sbjct: 540 -SELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 598
Query: 570 KELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
+L A E + KV L + Q + EE Q + ++E
Sbjct: 599 VKLSALNEALALDKVGLNQQLLQLE-EENQSVCSRME 634
Score = 46.4 bits (105), Expect = 3e-04
Identities = 81/412 (19%), Positives = 163/412 (39%), Gaps = 29/412 (7%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K + ++ + K+ L+ + + ++ +++D +L + L+G S E+L+ L +
Sbjct: 718 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 777
Query: 242 SRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
+ K QLE Q Q + +++ L+ E D+ + Q + A R AE
Sbjct: 778 QQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Query: 298 LEKEVT---RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
E + + A+E+ + + + K E HQ +AL+ ++ E E +++L +
Sbjct: 838 QEGKTALEQQKAAHEKEV-NQLREKWEKERSWHQ-QELAKALESLEREKMELEMRLKEQQ 895
Query: 355 SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATL-KYE 413
+++E+ + ++ AL + L L + L +
Sbjct: 896 TEMEAIQAQREEERTQAESAL---CQMQLETEKERVSLLETLLQTQKELADASQQLERLR 952
Query: 414 RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA 473
+D KL + T Q L Q+ L R+ +R L ++E + L +
Sbjct: 953 QDMKVQKLKEQETTGILQTQL-QEAQRELKEAARQ---HRDDLAALQEESSSLLQDKMD- 1007
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT-- 531
L +V+ L+ L D + K E+ E R ++E E + +T
Sbjct: 1008 -----LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET--QEYNRIQKELEREKASLTLS 1060
Query: 532 -KLRTQRDLLTASLERIGPQ-TKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ QR L+ + I Q L A QK++S ++E ++E+K+
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
Score = 45.6 bits (103), Expect = 5e-04
Identities = 46/192 (23%), Positives = 93/192 (48%), Gaps = 9/192 (4%)
Query: 171 KEHKDLKANWDKEKT----DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
KE L+ W+KE++ +L K + L+ + +E + K+Q +EM+ + + A
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 227 QSEVEMLKKELVKQ-TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY-ERDSYKDWQTQ 284
+S + ++ E K+ S E Q + +L + + +++ +K + E+++ QTQ
Sbjct: 913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ 972
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+ AQ+ L A ++ L A + + +K+ L++QV L S++ A Q L
Sbjct: 973 LQEAQRELKEAARQHRD--DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-RLV 1029
Query: 345 EAKVKLSSVESQ 356
E +V+ E+Q
Sbjct: 1030 EQEVQEKLRETQ 1041
Score = 45.2 bits (102), Expect = 7e-04
Identities = 48/203 (23%), Positives = 98/203 (48%), Gaps = 16/203 (7%)
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCT 248
++I L+ +L EA + + ++ +DE +AL E+E L++E +Q ++ ++
Sbjct: 1778 QEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQE--QQQAQGQE-E 1834
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC----NMAELEKEVTR 304
++K + + +Q LKE E +K+ Q++ ++ L + LE+ +
Sbjct: 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKE---QARRLEEELAVEGRRVQALEEVLGD 1891
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSA 363
LRA R A+ L L++Q + E + +Q +A+ L + +LE+ +
Sbjct: 1892 LRAESREQEKAL---LALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Query: 364 ARA--HGVESAGALRDALESALG 384
+++ H E+A A +AL+ ALG
Sbjct: 1949 SQSSRHQEEAARARAEALQEALG 1971
Score = 38.3 bits (85), Expect = 0.080
Identities = 83/451 (18%), Positives = 182/451 (40%), Gaps = 22/451 (4%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
A+E +LK + + D ++ +D+ LEA + Q ++ + E AL+GA +
Sbjct: 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 230 VEM-LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTA 288
M LK+ + EQ +L+ +L + Q + L +L E Q ++ A
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE----QEKALLA 1905
Query: 289 QKRLCNMAELEKEVTRLRANERSLRDA-ICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
++ C E EV R+L+D+ + + +L+E+ +L + Q + + A+
Sbjct: 1906 LQQQCAEQAQEHEV-----ETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 348 VKLSSVESQL---ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
+ +++ L + + H +E A R S L
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ ++ + + + L ++ + Q+R L+ + Q+ EK+
Sbjct: 2021 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQ-- 2078
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSL-QGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
L E + L V++L+ +L Q ++++ + + LE+L + E
Sbjct: 2079 -NLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNN-LEALPHSHKTSPMEE 2136
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
+ + D + R QR+L L+ QT+ + A+ + +A+ ++++
Sbjct: 2137 QSLKLDSLEPRLQREL--ERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVA 2194
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLKR 614
+ L+ + D E+ Q+++ +LE +R L++
Sbjct: 2195 MFLQASVLERDSEQ-QRLQDELELTRRALEK 2224
Score = 31.5 bits (68), Expect = 9.2
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 2/135 (1%)
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLER 546
E SL+ + + D KAL +R+ +TR R+ + R+ + + +LL ++
Sbjct: 366 ENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQ 425
Query: 547 IGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
+ K L + ++ + Q E+ L RE Q EEL+Q + LE
Sbjct: 426 WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-REL-LQKAREELRQQLEVLE 483
Query: 607 NSRIKLKRYSIVLVL 621
+L+R ++ L L
Sbjct: 484 QEAWRLRRVNVELQL 498
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 60.5 bits (140), Expect = 2e-08
Identities = 117/532 (21%), Positives = 219/532 (41%), Gaps = 43/532 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME- 149
E +R + + + Q+ + RV+ T+ + + L + + +E+ ++D + E
Sbjct: 906 EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQ--LERLRQDMKVQKLKEQ 963
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKE-------KTDLHKQIADLKDKLLEAN 202
+ + E AA++H+D A +E K DL KQ+ DLK +L+ +
Sbjct: 964 ETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQD 1023
Query: 203 VSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ 262
S + E+++ + E Q Q E+E K L EQ +L E + Q
Sbjct: 1024 DSQRLVEQEVQEKLRET-QEYNRIQKELEREKASLTLSLMEKEQ--RLLVLQEADSIRQQ 1080
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL 322
++++ ++++ + K+ +AQ L EKE L A E L + + +
Sbjct: 1081 ELSALRQDMQEAQGEQKEL-----SAQMELLRQEVKEKEADFL-AQEAQLLEELEASHIT 1134
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
E+Q+ EA + QL+L +L S ESQLE+ + + A A +L SA
Sbjct: 1135 EQQLRASLWAQEA-KAAQLQL-----RLRSTESQLEALAAEQQPGNQAQAQAQLASLYSA 1188
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG--KLNDLTTVRKNQ--ESLIHRL 438
L V L+ +++ A K L T + S +H+L
Sbjct: 1189 LQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL 1248
Query: 439 QKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA 498
+ L + RD R Q+ E+ LT T + + +Q L++ L ++ +
Sbjct: 1249 HQDLWKTQQTRDVLRDQVQKLEERLTDT------EAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 499 AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHL 556
+ +S E + T ++ R ++ ++ Q R+LL A+ E + Q V HL
Sbjct: 1303 KWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQ--VEHL 1360
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVA--LREGGAQADPEELQQMRQQLE 606
EA+ Q S +E+++ + A L+ +++ E Q +++Q E
Sbjct: 1361 -QAAVVEARAQAS-AAGILEEDLRTARSALKLKNEEVESERERAQALQEQGE 1410
Score = 52.0 bits (119), Expect = 6e-06
Identities = 107/570 (18%), Positives = 235/570 (41%), Gaps = 60/570 (10%)
Query: 88 SPWETKR--LKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDE 142
S WE K+ L+ +L+ + L+SR+ R E Q L + K +L Q + +
Sbjct: 1302 SKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQ 1361
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTA--AKEHKDLKANWDKEKTDLHKQIADLK---DK 197
AV + +++ TA A + K+ + ++E+ ++ +LK K
Sbjct: 1362 AAVVEAR----AQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 198 LLEANVS--------NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
L+ N++ ++++ ++ + EL + E ++ +E+L +L K+ + +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Query: 250 LKNQLEKQNFEFQQVTSKLKELEYE--------RDSYKDWQTQSKTAQKRLCNMAELEKE 301
+LEK + + ++E E + R+ KD +TQ + +L + + ++
Sbjct: 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQM 1537
Query: 302 VTRLRANERSLRDAI----CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ R + L+ + C L LEE H++ + + ++ ++ + +V L+ + L
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 358 ES-----WMSAARAHGVES-AGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
E +++ H +ES + L L+ HLT+++
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD 1657
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E ++ L R Q ++ +++ L RER ++L +++L + EE
Sbjct: 1658 QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERG---RELTT-QRQL-MQERAEE 1712
Query: 472 GAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
G G ++ ++ L+ + H H L+ L++++ + + + +
Sbjct: 1713 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHE--LQELKDQLEQQLQGLHRKVGETS 1770
Query: 532 KLRTQRD----LLTASLERIGPQTKV----LHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
L +QR+ +L L+ Q ++ L + A A Q +ELEA Q+E ++
Sbjct: 1771 LLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ-- 1828
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLK 613
+G + E+ ++ LE + + LK
Sbjct: 1829 ---AQGQEERVKEKADALQGALEQAHMTLK 1855
Score = 49.2 bits (112), Expect = 4e-05
Identities = 104/457 (22%), Positives = 182/457 (39%), Gaps = 20/457 (4%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E T + ++K+ D++ +L + L LL + + + + E
Sbjct: 183 EVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGRE 242
Query: 225 GAQSEVEMLK-KELVKQT-SRAEQCTQLKNQLEKQNFEFQQVTSKLKEL-EYERDSYKDW 281
AQ + + K +EL K+ R+++ QLK+Q + + E Q ++L L + +D+
Sbjct: 243 PAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDY 302
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSL-RDAICNKLLLEEQVHQLTSRV--EALQP 338
+ K ++ + LE T L +E SL R+A KL L++ + +T + E
Sbjct: 303 EKMIKALRE---TVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNI 359
Query: 339 VQLELHEAKVKL-SSVESQLESWMSAARAHGVESA-GALRDALESALGXXXXXXXXXXXX 396
Q HE ++L SS+ SQ + + V S R A++
Sbjct: 360 AQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLL 419
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
EE L+ K TG+ + L + + + L K L+ + R+ RQQL
Sbjct: 420 QQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQL 479
Query: 457 DCYEKE---LTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKALESL 512
+ E+E L + G A QQ E L R+ + +K ESL
Sbjct: 480 EVLEQEAWRLRRVNVELQLQGDSAQGQKEDQQEELHLAVRERERLQEMLMGLEAKQSESL 539
Query: 513 RNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI---S 569
+E+ RE E + + LR ++ +TA+L R L + N + +
Sbjct: 540 -SELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAA 598
Query: 570 KELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
+L A E + KV L + Q + EE Q + ++E
Sbjct: 599 VKLSALNEALALDKVGLNQQLLQLE-EENQSVCSRME 634
Score = 46.4 bits (105), Expect = 3e-04
Identities = 81/412 (19%), Positives = 163/412 (39%), Gaps = 29/412 (7%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K + ++ + K+ L+ + + ++ +++D +L + L+G S E+L+ L +
Sbjct: 718 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 777
Query: 242 SRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
+ K QLE Q Q + +++ L+ E D+ + Q + A R AE
Sbjct: 778 QQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Query: 298 LEKEVT---RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
E + + A+E+ + + + K E HQ +AL+ ++ E E +++L +
Sbjct: 838 QEGKTALEQQKAAHEKEV-NQLREKWEKERSWHQ-QELAKALESLEREKMELEMRLKEQQ 895
Query: 355 SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATL-KYE 413
+++E+ + ++ AL + L L + L +
Sbjct: 896 TEMEAIQAQREEERTQAESAL---CQMQLETEKERVSLLETLLQTQKELADASQQLERLR 952
Query: 414 RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA 473
+D KL + T Q L Q+ L R+ +R L ++E + L +
Sbjct: 953 QDMKVQKLKEQETTGILQTQL-QEAQRELKEAARQ---HRDDLAALQEESSSLLQDKMD- 1007
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT-- 531
L +V+ L+ L D + K E+ E R ++E E + +T
Sbjct: 1008 -----LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET--QEYNRIQKELEREKASLTLS 1060
Query: 532 -KLRTQRDLLTASLERIGPQ-TKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ QR L+ + I Q L A QK++S ++E ++E+K+
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
Score = 45.6 bits (103), Expect = 5e-04
Identities = 46/192 (23%), Positives = 93/192 (48%), Gaps = 9/192 (4%)
Query: 171 KEHKDLKANWDKEKT----DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
KE L+ W+KE++ +L K + L+ + +E + K+Q +EM+ + + A
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 227 QSEVEMLKKELVKQ-TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY-ERDSYKDWQTQ 284
+S + ++ E K+ S E Q + +L + + +++ +K + E+++ QTQ
Sbjct: 913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ 972
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+ AQ+ L A ++ L A + + +K+ L++QV L S++ A Q L
Sbjct: 973 LQEAQRELKEAARQHRD--DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-RLV 1029
Query: 345 EAKVKLSSVESQ 356
E +V+ E+Q
Sbjct: 1030 EQEVQEKLRETQ 1041
Score = 45.2 bits (102), Expect = 7e-04
Identities = 95/461 (20%), Positives = 188/461 (40%), Gaps = 40/461 (8%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ ++ +LH + + +++L E + + + SE ++ L +ALE + E E+L++E +
Sbjct: 508 EDQQEELHLAVRE-RERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEV 566
Query: 241 T---SRAEQ----CTQLKNQLEKQNFEFQQVTSKL----KELEYERDSYKDWQTQSKTAQ 289
T +RAEQ + +N L+ + + + KL + L ++ Q +
Sbjct: 567 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEEN 626
Query: 290 KRLCNMAELEKEVTRL----RANERSLRDAICNK-LLLEEQV---HQLTSRVEA-LQPVQ 340
+ +C+ E ++ A R+A+ K LE Q+ + + ++A L+ +Q
Sbjct: 627 QSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ 686
Query: 341 LELHEAKVKLS-------SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXX 393
E E + KLS + +QLE A+ A A+++ E+ +
Sbjct: 687 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEK-EALVREKAALEVRL 745
Query: 394 XXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYR 453
L E++ L ++ L + E +L+ ++ VT+ ++ +
Sbjct: 746 QAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQ 805
Query: 454 QQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLR 513
++ C + EL E + + A +QL ++ Q + + AH K + LR
Sbjct: 806 GEVRCLKLELDT-----ERSQAEQERDAAARQLAQAEQEGKTAL-EQQKAAHEKEVNQLR 859
Query: 514 NEVTRWREEAEGARRDVTKLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKEL 572
+W +E ++++ K + LE R+ Q + E + Q L
Sbjct: 860 E---KWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESAL 916
Query: 573 EAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
Q E +K +V+L E Q +EL QQLE R +K
Sbjct: 917 CQMQLETEKERVSLLETLLQTQ-KELADASQQLERLRQDMK 956
Score = 45.2 bits (102), Expect = 7e-04
Identities = 48/203 (23%), Positives = 98/203 (48%), Gaps = 16/203 (7%)
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCT 248
++I L+ +L EA + + ++ +DE +AL E+E L++E +Q ++ ++
Sbjct: 1778 QEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQE--QQQAQGQE-E 1834
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC----NMAELEKEVTR 304
++K + + +Q LKE E +K+ Q++ ++ L + LE+ +
Sbjct: 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKE---QARRLEEELAVEGRRVQALEEVLGD 1891
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSA 363
LRA R A+ L L++Q + E + +Q +A+ L + +LE+ +
Sbjct: 1892 LRAESREQEKAL---LALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Query: 364 ARA--HGVESAGALRDALESALG 384
+++ H E+A A +AL+ ALG
Sbjct: 1949 SQSSRHQEEAARARAEALQEALG 1971
Score = 38.3 bits (85), Expect = 0.080
Identities = 83/451 (18%), Positives = 182/451 (40%), Gaps = 22/451 (4%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
A+E +LK + + D ++ +D+ LEA + Q ++ + E AL+GA +
Sbjct: 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 230 VEM-LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTA 288
M LK+ + EQ +L+ +L + Q + L +L E Q ++ A
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE----QEKALLA 1905
Query: 289 QKRLCNMAELEKEVTRLRANERSLRDA-ICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
++ C E EV R+L+D+ + + +L+E+ +L + Q + + A+
Sbjct: 1906 LQQQCAEQAQEHEV-----ETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 348 VKLSSVESQL---ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
+ +++ L + + H +E A R S L
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ ++ + + + L ++ + Q+R L+ + Q+ EK+
Sbjct: 2021 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQ-- 2078
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSL-QGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
L E + L V++L+ +L Q ++++ + + LE+L + E
Sbjct: 2079 -NLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNN-LEALPHSHKTSPMEE 2136
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
+ + D + R QR+L L+ QT+ + A+ + +A+ ++++
Sbjct: 2137 QSLKLDSLEPRLQREL--ERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVA 2194
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLKR 614
+ L+ + D E+ Q+++ +LE +R L++
Sbjct: 2195 MFLQASVLERDSEQ-QRLQDELELTRRALEK 2224
Score = 31.5 bits (68), Expect = 9.2
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 2/135 (1%)
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLER 546
E SL+ + + D KAL +R+ +TR R+ + R+ + + +LL ++
Sbjct: 366 ENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQ 425
Query: 547 IGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
+ K L + ++ + Q E+ L RE Q EEL+Q + LE
Sbjct: 426 WEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-RE-LLQKAREELRQQLEVLE 483
Query: 607 NSRIKLKRYSIVLVL 621
+L+R ++ L L
Sbjct: 484 QEAWRLRRVNVELQL 498
>BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein.
Length = 790
Score = 60.1 bits (139), Expect = 2e-08
Identities = 111/541 (20%), Positives = 226/541 (41%), Gaps = 53/541 (9%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
K I E + N++ T ++ ++ + +E K ++ + ER++S+ ED
Sbjct: 238 KELIALQEDKHNYETTAKESLRRVLQE-KIEVVRKLSEVERSLSNTEDECTHLKEMNERT 296
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
++E A ++ N K+ +D K ++++ + + K ++ +M+E Q
Sbjct: 297 QEELRELANKYNG-AVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQE 355
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L Q+++E L+ + E+ T L+ +L + +T ++E + +++ Q
Sbjct: 356 L---QAKIEALQAD---NDFTNERLTALQEKLIVEG----HLTKAVEETKLSKEN----Q 401
Query: 283 TQSKTAQKRLCNMAELEK---EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
T++K + EK + T + +E+ L + + LL++ + S +EA Q +
Sbjct: 402 TRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEI 461
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
Q L + ++ + + +A E A R+ +E +
Sbjct: 462 Q-HLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHID 520
Query: 400 XXHLTEEV-ATLKYERDKATGKLNDL-------TTVRKNQESLIHRLQKRLLLVTRERDS 451
+L EE + + RD+ +++ V +++ I LQ+ L V E +
Sbjct: 521 TENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELER 580
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKS--LQGYRDLIA----AHDPHAH 505
+R+ YEKE+T + + + QQ E++ LQG + + A + H
Sbjct: 581 WRKAASEYEKEIT----SLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECH 636
Query: 506 SKALES--LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT---KVLHLTNN- 559
S E+ L +E+ R +E +++ +L + +L S + + Q K HL ++
Sbjct: 637 SLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSA 696
Query: 560 ------PAAEAQ-KQISKELEAAQEEIK--KLKVALREGGAQADPEELQQMRQQLENSRI 610
AE Q K + KE E Q + KLK + E Q+ +EL+Q + L+ R
Sbjct: 697 DLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLRE 756
Query: 611 K 611
K
Sbjct: 757 K 757
Score = 40.3 bits (90), Expect = 0.020
Identities = 86/415 (20%), Positives = 176/415 (42%), Gaps = 36/415 (8%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQ 263
++D++ + M LQA Q+E + L+KEL+ Q + T K L + E +
Sbjct: 209 DEDRLLSRLEVMGNQLQACSKNQTE-DSLRKELIALQEDKHNYETTAKESLRRVLQEKIE 267
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
V KL E+E + +D T K +R EL + + ++D + E
Sbjct: 268 VVRKLSEVERSLSNTEDECTHLKEMNER--TQEELRELANKYNGAVNEIKDLSDKLKVAE 325
Query: 324 EQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL--E 380
+ ++ + +A + +Q ++ E + K +++++E+ + A E AL++ L E
Sbjct: 326 GKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEA-LQADNDFTNERLTALQEKLIVE 384
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
L ++ TL ++K++ +D T + +++ L L K
Sbjct: 385 GHLTKAVEETKLSKENQTRAKE-SDFSDTLSPSKEKSS---DDTTDAQMDEQDLNEPLAK 440
Query: 441 RLLLV-----TRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ-LEKSLQGYR 494
LL + +Q++ KEL + +E A + +Q LE+ + YR
Sbjct: 441 VSLLKDDLQGAQSEIEAKQEIQHLRKEL---IEAQELARTSKQKCFELQALLEEERKAYR 497
Query: 495 DLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTKV 553
+ + +K ++ L+ ++ R + E R + +++ + RD L ++ + I +
Sbjct: 498 NQV-----EESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEI----LL 548
Query: 554 LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
LH AA+ + ++ + QEE+KK++ L A E ++ L+NS
Sbjct: 549 LH---QAAAKVASERDTDIASLQEELKKVRAELERWRKAA--SEYEKEITSLQNS 598
>AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22037 fis, clone HEP08868. ).
Length = 746
Score = 60.1 bits (139), Expect = 2e-08
Identities = 131/631 (20%), Positives = 262/631 (41%), Gaps = 49/631 (7%)
Query: 4 ESDMSLYSDVLEPFRRVINTEPPKDKLSASTNL---NFSDSTQSIKEGLSNLLT-FGKRK 59
++ M L S + + R+ E LSA+ SD + + EGL L K K
Sbjct: 102 KTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDL-EGLETTLAKTEKEK 160
Query: 60 SSIG-SVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKID-LIAAKAQITKLESRVNHQH 117
++ V +T D LR DS + E + +D L A + ++ L +
Sbjct: 161 QALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLS 220
Query: 118 TIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK 177
T E++ +E+EK E K +A SD++ D K +DL+
Sbjct: 221 TQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKK--RDLE 278
Query: 178 ANWDKEKTDLHKQI-ADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKE 236
N K + + + + L+ KL E ++D+I E+++++ E +A+ + + E
Sbjct: 279 INSVNSKYEDEQSLNSTLQRKLKE----HQDRIEELEEEL-EAERAMRAKIEQNRKREAE 333
Query: 237 LVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
L+K E+ L+++ + V S + EL +S + + +SK + + A
Sbjct: 334 LLKLRRELEEAA-LQSEATASTLRKKHVDS-MAELTEHVESLQ--RVKSKLEKDKQVMKA 389
Query: 297 ELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ 356
E++ + ++S +A + LE+ + + ++V L+ Q E++ + +L + S+
Sbjct: 390 EIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSE 449
Query: 357 LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
L +++ + ++ +L S + +A K++ D
Sbjct: 450 LSREYEESQSR-LNQILRIKTSLTSQVDDYKRQLDEESKSRSTA---VVSLANTKHDLDL 505
Query: 417 ATGKLNDLTTVRKNQESLIHRLQKRLLL--VTRERDSYR--QQLDCYEKELTVTLCGEEG 472
+L + + + L+ +L + E D+ + ++L+ +++L L E
Sbjct: 506 VKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEE 565
Query: 473 AGSVALLSARVQQLEKSLQGYR----DL-IAAHDPHAHSKALESLRN----EVTRWREEA 523
A A AR LEK+ Q + DL I +A + AL+ + + W+++
Sbjct: 566 AAETA--QARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKC 623
Query: 524 EGARRDVTKLRTQ-RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E + +V + + R +T S + + + E + + KE + QEEIK L
Sbjct: 624 EELQVEVDSSQKECRMYMTESFK--------IKTAYEESLEHLESVKKENKTLQEEIKDL 675
Query: 583 KVALREGGAQADPEELQQMRQQLENSRIKLK 613
L EGG ELQ+++++LE + +L+
Sbjct: 676 IDQLGEGGRSV--HELQKLKKKLEMEKEELQ 704
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/532 (18%), Positives = 221/532 (41%), Gaps = 46/532 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASL---IEQHKRDERAVSDMEDXXXXXXXXXXX 161
QI +LE + IR E++ + ++ L I+ ER+ D+E+
Sbjct: 222 QIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINS 281
Query: 162 XKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLK-DKLLEANVS-NKDQISEMKKDMDEL 219
++ + L+ + + + + +L+ ++ + A + N+ + +E+ K EL
Sbjct: 282 VNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKREAELLKLRREL 341
Query: 220 LQALEGAQSEVEMLKKE----LVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYER 275
+A +++ L+K+ + + T E ++K++LEK Q + +++ +L
Sbjct: 342 EEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDK---QVMKAEIDDLNASM 398
Query: 276 DSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
++ + + ++ ++L +++E +V L N+ + +AI +L E +L+ E
Sbjct: 399 ETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEI-NAIRTRLQAENS--ELSREYE 455
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWM---SAARAHGVESAGALRDALESALGXXXXXXX 391
Q ++ K L+S + + S +R+ V S + L+
Sbjct: 456 ESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQG 515
Query: 392 XXXXXXXXXXHLTEEVAT--LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER 449
L EV T KYE D A + +L ++ + + ++
Sbjct: 516 GKSELQRLVSKLNTEVTTWRTKYETD-AIQRTEELEETKRKLAARLQEAEEAAETAQARA 574
Query: 450 DSY---RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL-------IAA 499
S +Q+L ++LT+ L E+ + A L + + +K L ++ + +
Sbjct: 575 ASLEKNKQRLQAEVEDLTIDL--EKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDS 632
Query: 500 HDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNN 559
ES + + T + E E + +T ++ + ++++G + +H
Sbjct: 633 SQKECRMYMTESFKIK-TAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVH---- 687
Query: 560 PAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
E QK + K+LE +EE L+VAL E + + EE + +R QLE +++K
Sbjct: 688 ---ELQK-LKKKLEMEKEE---LQVALEEAESSLEVEESKVIRIQLELAQVK 732
Score = 34.3 bits (75), Expect = 1.3
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 9/124 (7%)
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
K L+ + E+ + +L K + Q++ +K+KELE E+ + + T Q
Sbjct: 29 KPLLNVARQEEEMKAKEEELRKAMAQTQELVNKVKELE-EKTATLSQEKNDLTIQ----- 82
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
L+ E L E L + K+ LE Q+ + R+E + + L AK KL
Sbjct: 83 ---LQAEQENLMDAEERLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGEL 139
Query: 355 SQLE 358
S L+
Sbjct: 140 SDLK 143
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 92/427 (21%), Positives = 180/427 (42%), Gaps = 44/427 (10%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ Q+ ++ + ++ ++L + EL E ++ QL+K L+
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALG------SQLQKKLKEL 1111
Query: 494 RDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKV 553
+ I + E L +E T R + E R D+++ + + ++ LE G T V
Sbjct: 1112 QARI--------EELEEELESERTA-RAKVEKLRSDLSR---ELEEISERLEEAGGATSV 1159
Query: 554 -LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------ELQQMRQQLE 606
+ + AE QK + ++LE A + + ALR+ A + E LQ+++Q+LE
Sbjct: 1160 QIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 607 NSRIKLK 613
+ + K
Sbjct: 1219 KEKSEFK 1225
Score = 43.2 bits (97), Expect = 0.003
Identities = 81/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
S A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 1124 SERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 92/427 (21%), Positives = 180/427 (42%), Gaps = 44/427 (10%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ Q+ ++ + ++ ++L + EL E ++ QL+K L+
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALG------SQLQKKLKEL 1111
Query: 494 RDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKV 553
+ I + E L +E T R + E R D+++ + + ++ LE G T V
Sbjct: 1112 QARI--------EELEEELESERTA-RAKVEKLRSDLSR---ELEEISERLEEAGGATSV 1159
Query: 554 -LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------ELQQMRQQLE 606
+ + AE QK + ++LE A + + ALR+ A + E LQ+++Q+LE
Sbjct: 1160 QIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 607 NSRIKLK 613
+ + K
Sbjct: 1219 KEKSEFK 1225
Score = 43.2 bits (97), Expect = 0.003
Identities = 81/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
S A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 1124 SERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 1118 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 1151
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 1152 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 1211 QRVKQKLEKEKSEFK 1225
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
Score = 41.9 bits (94), Expect = 0.006
Identities = 80/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 1124 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 59.3 bits (137), Expect = 4e-08
Identities = 116/542 (21%), Positives = 222/542 (40%), Gaps = 54/542 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
+RL+ +L A + + V+ +++ L EEKA+++ + ERA ++ +
Sbjct: 83 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 142
Query: 153 XXXXXXXXXXKDEFNTAA---KEHKDLKANWD---KEKTDLHKQIADLKDKLLEANVSNK 206
++E ++++ L+A + K D+ K + +L+ A +
Sbjct: 143 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 202
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTS 266
D +++ + DEL A E A+ +E+ + L Q R L+ + E +Q+
Sbjct: 203 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHER-----DLQGRDEAGEERRRQLAK 256
Query: 267 KLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L++ E ERD + +T + A+K+L E E+ L+A S EE V
Sbjct: 257 QLRDAEVERDEERKQRTLAVAARKKL------EGELEELKAQMASAGQG------KEEAV 304
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA-LRDALESALGX 385
QL ++ + E+ E + + SQ S R G+E+ L++ L ++
Sbjct: 305 KQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKGLEAEVLRLQEELAASDRA 362
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+ A + E+ + G+L L + ++S LL
Sbjct: 363 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-----NSELL-- 415
Query: 446 TRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA- 504
D YR+ L E LT L E + A S R QQLE+ +Q R + D A
Sbjct: 416 ---NDRYRKLLLQVES-LTTELSAERSFSAKAE-SGR-QQLERQIQELRGRLGEEDAGAR 469
Query: 505 --HSKALESLRNEVTRWREEAEGARRDVT---KL--RTQRDLLTASLERIGPQTKVLHLT 557
H + +L +++ + E+ E R+ KL R ++ L L+ + + +V
Sbjct: 470 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQ-VEEERRVADQL 528
Query: 558 NNPAAEAQ---KQISKELEAAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSRIKL 612
+ + KQ+ ++LE A+EE + + R + + E + M +++ R +L
Sbjct: 529 RDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 588
Query: 613 KR 614
+R
Sbjct: 589 RR 590
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 1118 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 1151
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 1152 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 1211 QRVKQKLEKEKSEFK 1225
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
Score = 41.9 bits (94), Expect = 0.006
Identities = 80/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 1124 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 1118 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 1151
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 1152 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 1211 QRVKQKLEKEKSEFK 1225
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
Score = 41.9 bits (94), Expect = 0.006
Identities = 80/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 898
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 1014
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 1072
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 1073 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 1124 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1181
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 1182 TLQHEATAAALRK 1194
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 527 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 585
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 586 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 637
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 638 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 687
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 688 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 743
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 744 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 799
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 800 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 858
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 859 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 918
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 919 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 951
Score = 49.2 bits (112), Expect = 4e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 79 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 131
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 132 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 188
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 189 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 241
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 242 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 301
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 302 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 361
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 362 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 395
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 396 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 454
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 455 QRVKQKLEKEKSEFK 469
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 717 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 772
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 773 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 832
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 833 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 889
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 890 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 943
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 944 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1003
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1004 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1062
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1063 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1122
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1123 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1176
Score = 41.9 bits (94), Expect = 0.006
Identities = 80/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 87 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 142
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 143 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 202
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 203 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 258
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 259 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 316
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 317 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 367
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 368 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 425
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 426 TLQHEATAAALRK 438
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 59.3 bits (137), Expect = 4e-08
Identities = 116/542 (21%), Positives = 222/542 (40%), Gaps = 54/542 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
+RL+ +L A + + V+ +++ L EEKA+++ + ERA ++ +
Sbjct: 1440 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1499
Query: 153 XXXXXXXXXXKDEFNTAA---KEHKDLKANWD---KEKTDLHKQIADLKDKLLEANVSNK 206
++E ++++ L+A + K D+ K + +L+ A +
Sbjct: 1500 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1559
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTS 266
D +++ + DEL A E A+ +E+ + L Q R L+ + E +Q+
Sbjct: 1560 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHER-----DLQGRDEAGEERRRQLAK 1613
Query: 267 KLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L++ E ERD + +T + A+K+L E E+ L+A S EE V
Sbjct: 1614 QLRDAEVERDEERKQRTLAVAARKKL------EGELEELKAQMASAGQG------KEEAV 1661
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA-LRDALESALGX 385
QL ++ + E+ E + + SQ S R G+E+ L++ L ++
Sbjct: 1662 KQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKGLEAEVLRLQEELAASDRA 1719
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+ A + E+ + G+L L + ++S LL
Sbjct: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-----NSELL-- 1772
Query: 446 TRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA- 504
D YR+ L E LT L E + A S R QQLE+ +Q R + D A
Sbjct: 1773 ---NDRYRKLLLQVES-LTTELSAERSFSAKAE-SGR-QQLERQIQELRGRLGEEDAGAR 1826
Query: 505 --HSKALESLRNEVTRWREEAEGARRDVT---KL--RTQRDLLTASLERIGPQTKVLHLT 557
H + +L +++ + E+ E R+ KL R ++ L L+ + + +V
Sbjct: 1827 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQ-VEEERRVADQL 1885
Query: 558 NNPAAEAQ---KQISKELEAAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSRIKL 612
+ + KQ+ ++LE A+EE + + R + + E + M +++ R +L
Sbjct: 1886 RDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945
Query: 613 KR 614
+R
Sbjct: 1946 RR 1947
Score = 42.3 bits (95), Expect = 0.005
Identities = 101/514 (19%), Positives = 188/514 (36%), Gaps = 42/514 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
E + ++EQ +R E + + +DE A+ K L+ +
Sbjct: 1083 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLR--------EAQ 1134
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSRAEQC 247
+A+ ++ L V+ + + + ++D+ E L+AL G + ++ + ++ R ++
Sbjct: 1135 AALAEAQEDLESERVA-RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEV 1193
Query: 248 TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE--LEKEVTRL 305
T+LK LE++ + +L++ + Q + K LE EV+ L
Sbjct: 1194 TELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSEL 1253
Query: 306 RANERSLRDA----ICNKLLLEEQVHQLTSR-----------VEALQPVQLELHEAKVKL 350
RA SL+ A + LE Q+ ++ R E LQ Q EL L
Sbjct: 1254 RAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGAL 1313
Query: 351 SSVES---QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEV 407
+ ES +L +S+ A ++ L++ + L L EE
Sbjct: 1314 NEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEA 1373
Query: 408 ATLK---YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
A + E A +L++ ++ + + ++ RE ++ Q+L EK T
Sbjct: 1374 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRL--AEKTET 1431
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES---LRNEVTRWRE 521
V L LE+ Q L A E LR R R
Sbjct: 1432 VDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA 1491
Query: 522 EAEGARRDVTKLRTQRDL--LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEI 579
EAEG R+ L R L + E + Q + L ++ + K + +
Sbjct: 1492 EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERAC 1551
Query: 580 KKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ + A + AQ EL+ E+++++L+
Sbjct: 1552 RVAEQAANDLRAQV--TELEDELTAAEDAKLRLE 1583
Score = 39.5 bits (88), Expect = 0.035
Identities = 90/418 (21%), Positives = 162/418 (38%), Gaps = 27/418 (6%)
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
SE+++ M E Q E ++++ ++EL +RAE + QL K E Q ++ +
Sbjct: 1082 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQ 1141
Query: 270 E-LEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANE--RSLRDAICNKL--LLE 323
E LE ER + + Q + + L ELE + A + RS R+ +L LE
Sbjct: 1142 EDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE 1201
Query: 324 EQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
E+ + V+ L Q L E +L +W A E LR L S
Sbjct: 1202 EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE-VSELRAELSSL 1260
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRL 442
+ + R +A KL +N ++ + +
Sbjct: 1261 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1320
Query: 443 LLVTRERDSYRQQL-DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AA 499
+ +++E S QL D E L EE +A L +RV+ +E G R+ + A
Sbjct: 1321 IRLSKELSSTEAQLHDAQE------LLQEETRAKLA-LGSRVRAMEAEAAGLREQLEEEA 1373
Query: 500 HDPHAHSKALESLRNEVTRWR---EEAEGARR--DVTKLRTQRDLLTASLERIGPQTKVL 554
+ L++ + +++ WR EE GA + + R R+ A +R+ +T+ +
Sbjct: 1374 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE-AEALTQRLAEKTETV 1432
Query: 555 HLTNNPAAEAQKQI---SKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+++ + +LE ++ + L+ R+ E+ +R E R
Sbjct: 1433 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERER 1490
Score = 38.3 bits (85), Expect = 0.080
Identities = 90/463 (19%), Positives = 174/463 (37%), Gaps = 33/463 (7%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
++L+ +E +L ++A L+++ + + +E+ + +E L + E+E++
Sbjct: 882 QELQQQSAREVGELQGRVAQLEEERARLAEQLRAE-AELCAEAEETRGRLAARKQELELV 940
Query: 234 KKELVKQTSRAEQCT---------------QLKNQLE-----KQNFEFQQVTSKLKELEY 273
EL + E+C+ +L+ LE +Q + ++VT++ K ++
Sbjct: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000
Query: 274 ERDSYKDWQTQSKTAQKRLC-NMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E D SK ++ C + +LR RS R +I + Q R
Sbjct: 1001 EEDLLLLEDQNSKLSKSGSCWKIVWPSSHPRQLRRRRRS-RASISYGSNMRPQSQTWRDR 1059
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXX 392
+ + + EL + K +L S+L+ M + E L E
Sbjct: 1060 LRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE 1119
Query: 393 XXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
L E A L ++ + T K + L L+ + DS
Sbjct: 1120 GGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDST 1179
Query: 453 RQQLDCYEK-ELTVTLCGEEGAGSVALLSARVQQL-EKSLQGYRDLIAAHDPHAHSKALE 510
Q + K E VT + + A VQ+L ++ Q +L + K
Sbjct: 1180 NAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1239
Query: 511 SLRNEVTRWREEAEGA--RRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI 568
E TR EAE + R +++ L+T R R+ Q + + A+ +
Sbjct: 1240 ----EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1295
Query: 569 SKELEAAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSR 609
+++L+ AQ E++ + AL E ++ +EL QL +++
Sbjct: 1296 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1338
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 1283 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 1341
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 1342 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1393
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1394 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1499
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1556 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1614
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1615 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1674
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1707
Score = 48.8 bits (111), Expect = 6e-05
Identities = 86/407 (21%), Positives = 170/407 (41%), Gaps = 38/407 (9%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 887
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 888 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 944
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 945 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 997
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 1057
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 1058 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 1117
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGA---------RRDVTKLRTQ 536
LE+ L+ R A + + E E++ EEA GA +R+ + +
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRE--LEEISERLEEAGGATSCQIEMNKKREAEFQKMR 1175
Query: 537 RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
RDL A+L+ + + AE +QI L+ +++++K K
Sbjct: 1176 RDLEEATLQHEATAAALRKKHADSVAELGEQID-NLQRVKQKLEKEK 1221
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1473 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1528
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1645
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1759
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1760 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1932
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 59.3 bits (137), Expect = 4e-08
Identities = 96/454 (21%), Positives = 182/454 (40%), Gaps = 36/454 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 922 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 980
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 981 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 1032
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 1033 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 1082
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 1083 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 1138
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 1139 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 1194
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 1195 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 1253
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 1254 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 1313
Query: 586 LREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
R QA+ EEL+ + +Q E SR KL ++
Sbjct: 1314 ERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 1346
Score = 49.2 bits (112), Expect = 4e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 474 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 526
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 527 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 583
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 584 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 636
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 637 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 696
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 697 DLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 756
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 757 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 790
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 791 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 849
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 850 QRVKQKLEKEKSEFK 864
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 1112 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 1167
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1168 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1227
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 1228 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 1284
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 1285 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 1338
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L E+++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 1339 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1398
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 1399 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1457
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1458 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1517
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1518 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1571
Score = 41.9 bits (94), Expect = 0.006
Identities = 80/373 (21%), Positives = 145/373 (38%), Gaps = 25/373 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ LK+ L ++ K E+++ M LLQ Q +V+ + L
Sbjct: 482 AEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQDNL 537
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
R +Q + K QLE + E + +E+ E + K + KR + E
Sbjct: 538 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 597
Query: 298 --LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
L K A E +++ L+E + +LT +ALQ E H+ + E
Sbjct: 598 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ----EAHQQALDDLQAEE 653
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ ++ A+ + L +LE LT+E + + E D
Sbjct: 654 DKVNTLTKAKVKLEQQVDDLEGSLEQE-KKVRMDLERAKRKLEGDLKLTQE-SIMDLEND 711
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAG 474
K L K ++ ++ L R+ + + QL KEL + EE
Sbjct: 712 K-----QQLDERLKKKDFELNALNARI----EDEQALGSQLQKKLKELQARIEELEEELE 762
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKL 533
+ A+V++L L R+L + + S++ E+ + RE E + RRD+ +
Sbjct: 763 AERTARAKVEKLRSDLS--RELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 820
Query: 534 RTQRDLLTASLER 546
Q + A+L +
Sbjct: 821 TLQHEATAAALRK 833
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 59.3 bits (137), Expect = 4e-08
Identities = 116/542 (21%), Positives = 222/542 (40%), Gaps = 54/542 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
+RL+ +L A + + V+ +++ L EEKA+++ + ERA ++ +
Sbjct: 1016 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1075
Query: 153 XXXXXXXXXXKDEFNTAA---KEHKDLKANWD---KEKTDLHKQIADLKDKLLEANVSNK 206
++E ++++ L+A + K D+ K + +L+ A +
Sbjct: 1076 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1135
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTS 266
D +++ + DEL A E A+ +E+ + L Q R L+ + E +Q+
Sbjct: 1136 DLRAQVTELEDELTAA-EDAKLRLEVTVQALKTQHER-----DLQGRDEAGEERRRQLAK 1189
Query: 267 KLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L++ E ERD + +T + A+K+L E E+ L+A S EE V
Sbjct: 1190 QLRDAEVERDEERKQRTLAVAARKKL------EGELEELKAQMASAGQG------KEEAV 1237
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA-LRDALESALGX 385
QL ++ + E+ E + + SQ S R G+E+ L++ L ++
Sbjct: 1238 KQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKGLEAEVLRLQEELAASDRA 1295
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+ A + E+ + G+L L + ++S LL
Sbjct: 1296 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-----NSELL-- 1348
Query: 446 TRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHA- 504
D YR+ L E LT L E + A S R QQLE+ +Q R + D A
Sbjct: 1349 ---NDRYRKLLLQVES-LTTELSAERSFSAKAE-SGR-QQLERQIQELRGRLGEEDAGAR 1402
Query: 505 --HSKALESLRNEVTRWREEAEGARRDVT---KL--RTQRDLLTASLERIGPQTKVLHLT 557
H + +L +++ + E+ E R+ KL R ++ L L+ + + +V
Sbjct: 1403 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQ-VEEERRVADQL 1461
Query: 558 NNPAAEAQ---KQISKELEAAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSRIKL 612
+ + KQ+ ++LE A+EE + + R + + E + M +++ R +L
Sbjct: 1462 RDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1521
Query: 613 KR 614
+R
Sbjct: 1522 RR 1523
Score = 51.6 bits (118), Expect = 8e-06
Identities = 112/549 (20%), Positives = 219/549 (39%), Gaps = 44/549 (8%)
Query: 92 TKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDX 151
+++++ + + I +LE+ + + R+++Q+ EK + + K+ E + +ED
Sbjct: 531 SRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL----EKVTTEAKMKKFEEDLLLLEDQ 586
Query: 152 XXXXXXXXXXXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD- 207
+D EF++ A E ++ + +K + IAD++D+L + ++
Sbjct: 587 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 646
Query: 208 ---------QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQN 258
+ SE+++ M E Q E ++++ ++EL +RAE + QL K
Sbjct: 647 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 706
Query: 259 FEFQQVTSKLKE-LEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANE--RSLRD 314
E Q ++ +E LE ER + + Q + + L ELE + A + RS R+
Sbjct: 707 REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE 766
Query: 315 AICNKL--LLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+L LEE+ + V+ L Q L E +L +W A E
Sbjct: 767 QEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE- 825
Query: 372 AGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQ 431
LR L S + + R +A KL +N
Sbjct: 826 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV 885
Query: 432 ESLIHRLQKRLLLVTRERDSYRQQL-DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL 490
++ + + + +++E S QL D E L EE +A L +RV+ +E
Sbjct: 886 SGALNEAESKTIRLSKELSSTEAQLHDAQE------LLQEETRAKLA-LGSRVRAMEAEA 938
Query: 491 QGYRDLI--AAHDPHAHSKALESLRNEVTRWR---EEAEGARR--DVTKLRTQRDLLTAS 543
G R+ + A + L++ + +++ WR EE GA + + R R+ A
Sbjct: 939 AGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE-AEAL 997
Query: 544 LERIGPQTKVLHLTNNPAAEAQKQI---SKELEAAQEEIKKLKVALREGGAQADPEELQQ 600
+R+ +T+ + Q+++ + +LE ++ + L+ R+ E+
Sbjct: 998 TQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1057
Query: 601 MRQQLENSR 609
+R E R
Sbjct: 1058 LRAVEERER 1066
Score = 42.7 bits (96), Expect = 0.004
Identities = 91/464 (19%), Positives = 177/464 (38%), Gaps = 35/464 (7%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
++L+ +E +L ++A L+++ + + +E+ + +E L + E+E++
Sbjct: 458 QELQQQSAREVGELQGRVAQLEEERARLAEQLRAE-AELCAEAEETRGRLAARKQELELV 516
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC 293
EL + E+C++ + Q EK+ + Q + LE E + + Q + T + ++
Sbjct: 517 VSELEARVGEEEECSR-QMQTEKKRLQ-QHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 574
Query: 294 NMAE----LEKEVTRLRANERSLRDAIC----------------NKLLL--EEQVHQLTS 331
E LE + ++L + L D + NKL L E + +
Sbjct: 575 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 634
Query: 332 RVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
R+ + + EL + K +L S+L+ M + E L E
Sbjct: 635 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 694
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
L E A L ++ + T K + L L+ + DS
Sbjct: 695 EGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 754
Query: 452 YRQQLDCYEK-ELTVTLCGEEGAGSVALLSARVQQL-EKSLQGYRDLIAAHDPHAHSKAL 509
Q + K E VT + + A VQ+L ++ Q +L + K
Sbjct: 755 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 814
Query: 510 ESLRNEVTRWREEAEGA--RRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
E TR EAE + R +++ L+T R R+ Q + + A+ +
Sbjct: 815 W----EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 870
Query: 568 ISKELEAAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSR 609
+++L+ AQ E++ + AL E ++ +EL QL +++
Sbjct: 871 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 914
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 58.8 bits (136), Expect = 5e-08
Identities = 94/445 (21%), Positives = 178/445 (40%), Gaps = 35/445 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+ +L D EK L Q+ K + K Q+ E K + L AL+ A+ + +
Sbjct: 499 ENGELSRQLD-EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCD 557
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+L+++ ++T E +L+ L K N E Q +K YE D+ + + + +K
Sbjct: 558 LLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKL 609
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E E+ V + A C+ L E+ H+L + +E L + A L
Sbjct: 610 AQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMVDVERSNAAAAALD 659
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ + ++ + ES L + + A HL T K
Sbjct: 660 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE----TFK 715
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E +++DLT + IH L+K V ++ ++ + +L +E +L EE
Sbjct: 716 RENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQSALEEAEASLEHEE 771
Query: 472 GAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV---TRWREEAEGA 526
G A L ++E+ L +D H + ++SL+ + TR R EA
Sbjct: 772 GKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRV 830
Query: 527 RRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA 585
++ + + ++ + R+ + K + + + Q Q+ + A + + + +
Sbjct: 831 KKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIV 890
Query: 586 LREGG-AQADPEELQQMRQQLENSR 609
R QA+ EEL+ + +Q E SR
Sbjct: 891 ERRNNLLQAELEELRAVVEQTERSR 915
Score = 50.0 bits (114), Expect = 2e-05
Identities = 96/435 (22%), Positives = 184/435 (42%), Gaps = 60/435 (13%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
K K L + + +++ MK++ L +ALE +++ + L++++V Q KN L
Sbjct: 51 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMV-------SLLQEKNDL 103
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV-TRLRANERSLR 313
+ Q Q L + E D + Q + K + E E+E+ L A +R L
Sbjct: 104 QLQ---VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLE 160
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D C++L + +LT L V+ E H + K+ ++ ++ + + A +
Sbjct: 161 DE-CSELKRDIDDLELT-----LAKVEKEKHATENKVKNLTEEM-AGLDEIIAKLTKEKK 213
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQES 433
AL++A + AL L ++V L+ ++ DL ++ E
Sbjct: 214 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEG 273
Query: 434 LIHRLQKRLLLVTRERDSYRQQL---DCYEKELTVTLCGEEGAGS-----VALLSARVQQ 485
+ Q+ ++ + ++ ++L D L + E+ GS + L AR+++
Sbjct: 274 DLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEE 333
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE+ L+ R A +K +E LR++++R EE ++ LE
Sbjct: 334 LEEELEAERT--------ARAK-VEKLRSDLSRELEE-----------------ISERLE 367
Query: 546 RIGPQTKV-LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPE------EL 598
G T V + + AE QK + ++LE A + + ALR+ A + E L
Sbjct: 368 EAGGATSVQIEMNKKREAEFQK-MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 426
Query: 599 QQMRQQLENSRIKLK 613
Q+++Q+LE + + K
Sbjct: 427 QRVKQKLEKEKSEFK 441
Score = 42.7 bits (96), Expect = 0.004
Identities = 86/474 (18%), Positives = 193/474 (40%), Gaps = 34/474 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 689 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 744
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 745 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 804
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ 263
++ + ++ +D ++ A + ++ +L + + ++ + +KQ +
Sbjct: 805 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKS 861
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CNK 319
+ S LK+ + + D K N+A +E+ L+A LR + ++
Sbjct: 862 LQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERSR 915
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
L +E++ + + RV+ L L K K LS +++++E + R ++ A+
Sbjct: 916 KLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 975
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESL 434
DA A ++ + + L++ D+A L + E+
Sbjct: 976 TDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1034
Query: 435 IHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ L R +S + + +T EE ++ L V +L+ ++ Y
Sbjct: 1035 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1094
Query: 494 RDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 1095 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 1148
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 58.8 bits (136), Expect = 5e-08
Identities = 90/435 (20%), Positives = 193/435 (44%), Gaps = 30/435 (6%)
Query: 188 HKQIADLKDKLL---EANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
H++ A K K+L +A ++ D +I +++ + EL +A + A + ++ + Q
Sbjct: 791 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 850
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQ-KRLCNMAELEKEV 302
+ Q K LE Q + + KL+E + E+ S++D +++ + + LE E
Sbjct: 851 ISELRQQKFYLETQAGKLEAQNRKLEE-QLEKISHQDHSDKNRLLELETRLREVSLEHEE 909
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+L +R L + +L L+E+ QLT+ A ++ +L +AK +L ++ E +
Sbjct: 910 QKLEL-KRQLTEL---QLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQ 965
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A AH E DAL ++ L + L + D+A+G +
Sbjct: 966 ALTAHRDEIQRKF-DALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND 1024
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
++ +R + L + +R + +T S +Q ++ + T+ EE + L+
Sbjct: 1025 EIVQLRSEVDHLRREITEREMQLT----SQKQTMEALKTTCTML---EEQVMDLEALNDE 1077
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTA 542
+ + E+ + +R ++ + E R T E+ AR D ++ R ++
Sbjct: 1078 LLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDT---EKQSRARAD-QRITESRQVVEL 1133
Query: 543 SLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQ--- 599
+++ + K L A + QK ++ L +++K K A+ E A++ ++L+
Sbjct: 1134 AVK----EHKAEILALQQALKEQKLKAESLSDKLNDLEK-KHAMLEMNARSLQQKLETER 1188
Query: 600 QMRQQLENSRIKLKR 614
+++Q+L + KL++
Sbjct: 1189 ELKQRLLEEQAKLQQ 1203
Score = 48.4 bits (110), Expect = 7e-05
Identities = 104/521 (19%), Positives = 218/521 (41%), Gaps = 53/521 (10%)
Query: 103 KAQITKLESRVNHQHTIR-KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXX 161
+ Q KL+ ++ + +EM+++ + + L+ +R + S++ +
Sbjct: 543 REQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAA------ 596
Query: 162 XKDEFNTAAKE--HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDEL 219
+EF A E HK LKA D+ K ++ + KL + N + +I E+++ +++
Sbjct: 597 --EEFKRKATECQHKLLKAK-DQGKPEVGEYA-----KLEKINAEQQLKIQELQEKLEKA 648
Query: 220 LQA-------LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
++A L+ + E ++EL K +R + ++ +L + + +K+K LE
Sbjct: 649 VKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEERRHSLENKVKRLE 708
Query: 273 -YERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK-LLLEEQVH 327
ER + D QT+S+ Q+ + ELE++ + + + L + K EE++
Sbjct: 709 TMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIK 768
Query: 328 QLTSRVE-----------ALQPVQLELHEAKVKLSSVESQLESWMSAARA---HGVESAG 373
L ++++ +Q + E HE LS ++ + + S R+ VE +
Sbjct: 769 VLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSE 828
Query: 374 ALRDALESAL---GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKN 430
A + A S+L +L + L+ + K +L ++ +
Sbjct: 829 ANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHS 888
Query: 431 QESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL 490
++ + L+ RL V+ E + + +L EL ++L +E + L A LE L
Sbjct: 889 DKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSL--QERESQLTALQAARAALESQL 946
Query: 491 QGYRDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG 548
+ + + A +AL + R+E+ R + + +T L Q + LT +
Sbjct: 947 RQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELN 1006
Query: 549 PQTKVLHLTNNPAAEAQK---QISKELEAAQEEIKKLKVAL 586
Q L + A+ A Q+ E++ + EI + ++ L
Sbjct: 1007 NQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQL 1047
Score = 40.3 bits (90), Expect = 0.020
Identities = 91/498 (18%), Positives = 190/498 (38%), Gaps = 32/498 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
++ + E + L Q+++ E + + + + EH++ K
Sbjct: 855 RQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLEL 914
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML---KKEL 237
++ T+L + + + +L + S++++ EL + A+ E++ L + E+
Sbjct: 915 KRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEI 974
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
++ + LE+Q Q+T EL ++ Y Q + + +
Sbjct: 975 QRKFDALRNSCTVITDLEEQ---LNQLTEDNAELN-NQNFYLSKQLDEASGAND--EIVQ 1028
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
L EV LR R + + ++ + L + L+ ++L +L E Q
Sbjct: 1029 LRSEVDHLR---REITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQW 1085
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E+W S + +R+ L+ L + E +K + +
Sbjct: 1086 EAWRSVLGDEKSQFECRVRE-LQRMLDTEKQSRARADQRITESRQVVE--LAVKEHKAEI 1142
Query: 418 TGKLNDLTTVRKNQESL---IHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAG 474
L + ESL ++ L+K+ ++ S +Q+L+ E+EL L EE A
Sbjct: 1143 LALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET-ERELKQRLL-EEQAK 1200
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA-----LESLRNEVTRWREEAEGARRD 529
+ + + + QG ++ + D ++ LE+++ + + + EG
Sbjct: 1201 LQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQ 1260
Query: 530 VTKLRTQRDLLTASLERIGPQTKVL--HLTNNPAAEAQKQIS-KELEAAQEEIKKLKVAL 586
TKL D L A +++ + K L +PA Q + EL+ A E+ +K + A
Sbjct: 1261 QTKL---IDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEK-EKARCAE 1316
Query: 587 REGGAQADPEELQQMRQQ 604
E Q EL+ R++
Sbjct: 1317 LEEALQKTRIELRSAREE 1334
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 58.8 bits (136), Expect = 5e-08
Identities = 90/435 (20%), Positives = 193/435 (44%), Gaps = 30/435 (6%)
Query: 188 HKQIADLKDKLL---EANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
H++ A K K+L +A ++ D +I +++ + EL +A + A + ++ + Q
Sbjct: 23 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 82
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQ-KRLCNMAELEKEV 302
+ Q K LE Q + + KL+E + E+ S++D +++ + + LE E
Sbjct: 83 ISELRQQKFYLETQAGKLEAQNRKLEE-QLEKISHQDHSDKNRLLELETRLREVSLEHEE 141
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+L +R L + +L L+E+ QLT+ A ++ +L +AK +L ++ E +
Sbjct: 142 QKLEL-KRQLTEL---QLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQ 197
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A AH E DAL ++ L + L + D+A+G +
Sbjct: 198 ALTAHRDEIQRKF-DALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND 256
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
++ +R + L + +R + +T S +Q ++ + T+ EE + L+
Sbjct: 257 EIVQLRSEVDHLRREITEREMQLT----SQKQTMEALKTTCTML---EEQVMDLEALNDE 309
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTA 542
+ + E+ + +R ++ + E R T E+ AR D ++ R ++
Sbjct: 310 LLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDT---EKQSRARAD-QRITESRQVVEL 365
Query: 543 SLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQ--- 599
+++ + K L A + QK ++ L +++K K A+ E A++ ++L+
Sbjct: 366 AVK----EHKAEILALQQALKEQKLKAESLSDKLNDLEK-KHAMLEMNARSLQQKLETER 420
Query: 600 QMRQQLENSRIKLKR 614
+++Q+L + KL++
Sbjct: 421 ELKQRLLEEQAKLQQ 435
Score = 41.1 bits (92), Expect = 0.011
Identities = 85/484 (17%), Positives = 185/484 (38%), Gaps = 29/484 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
++ + E + L Q+++ E + + + + EH++ K
Sbjct: 87 RQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLEL 146
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML---KKEL 237
++ T+L + + + +L + S++++ EL + A+ E++ L + E+
Sbjct: 147 KRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEI 206
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
++ + LE+Q Q+T EL ++ Y Q + + +
Sbjct: 207 QRKFDALRNSCTVITDLEEQ---LNQLTEDNAELN-NQNFYLSKQLDEASGAND--EIVQ 260
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
L EV LR R + + ++ + L + L+ ++L +L E Q
Sbjct: 261 LRSEVDHLR---REITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQW 317
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E+W S + +R+ L+ L + E +K + +
Sbjct: 318 EAWRSVLGDEKSQFECRVRE-LQRMLDTEKQSRARADQRITESRQVVE--LAVKEHKAEI 374
Query: 418 TGKLNDLTTVRKNQESL---IHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAG 474
L + ESL ++ L+K+ ++ S +Q+L+ E+EL L EE A
Sbjct: 375 LALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET-ERELKQRLL-EEQAK 432
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA-----LESLRNEVTRWREEAEGARRD 529
+ + + + QG ++ + D ++ LE+++ + + + EG
Sbjct: 433 LQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQ 492
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG 589
TKL D L A +++ + KV N +K+ ++ E +E ++K ++ LR
Sbjct: 493 QTKL---IDFLQAKMDQPAKKKKVPLQYNELKLALEKEKARCAE-LEEALQKTRIELRSA 548
Query: 590 GAQA 593
+A
Sbjct: 549 REEA 552
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 58.4 bits (135), Expect = 7e-08
Identities = 88/420 (20%), Positives = 170/420 (40%), Gaps = 35/420 (8%)
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
K Q+ E K + L AL+ A+ + ++L+++ ++T E +L+ L K N E Q
Sbjct: 16 KRQLEEEVKAKNALAHALQSARHDCDLLREQYEEET---EAKARLQGDLSKANSEVAQWR 72
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ 325
+K YE D+ + + + +K + E E+ V + A C+ L E+
Sbjct: 73 TK-----YETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAK--------CSSL--EKT 117
Query: 326 VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
H+L + +E L + A L + + ++ + ES L + + A
Sbjct: 118 KHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSL 177
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
HL T K E +++DLT + IH L+K V
Sbjct: 178 STELFKLKNAYEESLEHLE----TFKRENKNLQEEISDLTEQLGSSGKTIHELEK----V 229
Query: 446 TRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPH 503
++ ++ + +L +E +L EEG A L ++E+ Q +D
Sbjct: 230 RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQ-EKDEEMEQAKR 288
Query: 504 AHSKALESLRNEV---TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNN 559
H + ++SL+ + TR R EA ++ + + ++ + R+ + K + +
Sbjct: 289 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 348
Query: 560 PAAEAQKQISKELEAAQEEIKKLKVALREGG-AQADPEELQQMRQQLENSRIKLKRYSIV 618
+ Q Q+ + A + + + + R QA+ EEL+ + +Q E SR KL ++
Sbjct: 349 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR-KLAEQELI 407
Score = 40.7 bits (91), Expect = 0.015
Identities = 97/479 (20%), Positives = 191/479 (39%), Gaps = 44/479 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + + ++E
Sbjct: 173 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGSSGKTIHELEK 228
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
K E +A +E +A+ + E+ + + A L+ ++A + K Q
Sbjct: 229 VRKQLEAE----KMELQSALEE---AEASLEHEEGKILR--AQLEFNQIKAEIERKRQ-- 277
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+KD +E+ QA V+ L+ L +T + ++K ++E E + S
Sbjct: 278 --EKD-EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 334
Query: 271 LEYE-RDSYKDWQTQSKTAQKRLC-----------NMAELEKEVTRLRANERSLRDAI-- 316
+ E + K Q+ K Q +L N+A +E+ L+A LR +
Sbjct: 335 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 394
Query: 317 --CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVE 370
++ L E+++ + + RV+ L L K K LS +++++E + R +
Sbjct: 395 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 454
Query: 371 SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRK 429
+ A+ DA A ++ + + L++ D+A L +
Sbjct: 455 AKKAITDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQ 513
Query: 430 NQESLIHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEK 488
E+ + L+ L R +S + + +T EE ++ L V +L+
Sbjct: 514 KLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQL 573
Query: 489 SLQGYRDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASL 544
++ Y+ + A++ +++E+ E A+ A V KLR + RD+ T L
Sbjct: 574 KVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGL 632
>BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 415 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 470
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 471 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 528
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 529 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 587
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 588 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 643
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 644 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 703
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 704 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 763
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 764 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 823
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 824 KASLDKELMAQKLVQAEREAQASLREQ 850
Score = 53.2 bits (122), Expect = 3e-06
Identities = 114/531 (21%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
K+DL AQ+ + +S + + ++ + EE+ L E E A +E
Sbjct: 615 KLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVA 674
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKD 215
+ + T E L+ ++ L +Q++ + +L +A + Q+ +++
Sbjct: 675 EQAQEALEQQLPTLRHERSQLQ----EQLAQLSRQLSGREQELEQARREAQRQVEALERA 730
Query: 216 MDEL-LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
E A E A V+++ E +T +E+ T+L+ + E +V +L +LE
Sbjct: 731 AREKEALAKEHAGLAVQLVAAEREGRTL-SEEATRLRLEKEALEGSLFEVQRQLAQLEAR 789
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRV 333
R+ Q +++ Q L L E+ LR + ++ A +K L+ +++ Q
Sbjct: 790 RE-----QLEAE-GQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREA 843
Query: 334 EALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXX 393
+A Q HE L ++ + E+ A + L+ E L
Sbjct: 844 QASLREQRAAHEED--LQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKE-- 899
Query: 394 XXXXXXXXHLTEEVATLKYERDKA-----TGKLNDLTTVRKNQESLIHRLQ-KRLLLVTR 447
L+EE+A L+ ERD+ + K L+ + +L +L R L T
Sbjct: 900 --------ELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATI 951
Query: 448 ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK 507
+ RQ+ D ++ E+ +V L++ + + L+ R+ AA AH++
Sbjct: 952 SLEMERQKRDAQSRQ-------EQDRSTVNALTSEL----RDLRAQREEAAA----AHAQ 996
Query: 508 ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL-----TNNPAA 562
+ L+ + ++ + R+ +LRTQ LL + R G + ++L +
Sbjct: 997 EVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDA--RDGLRRELLEAQRKLRESQEGR 1054
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
E Q+Q + EL + E K + ALR EEL+ ++ E+ RI LK
Sbjct: 1055 EVQRQEAGELRRSLGEGAKEREALRRSN-----EELRSAVKKAESERISLK 1100
>BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 58.4 bits (135), Expect = 7e-08
Identities = 101/447 (22%), Positives = 185/447 (41%), Gaps = 40/447 (8%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKK--ELV--KQTS 242
L KQ++D + + + ++Q+ ++ D +QA E AQ EV+ L+ EL+ ++++
Sbjct: 415 LRKQLSDSESE----RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSN 470
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
A + Q E+ E +++ + +EL +RD ++ Q + R+ ELE+
Sbjct: 471 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARV--RRELERSH 528
Query: 303 TRLRANERSLRDAICNKLL-LEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+L E R + +L+ + E + + T + + LQ + E+ EA K + +LE M
Sbjct: 529 RQLEQLEGK-RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSM 587
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK-------YER 414
+ RA E A +L+D+L L EE + L+ E
Sbjct: 588 TKLRA---EEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 643
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE----------LT 464
A + L +R QE L+ L + + +++ QQL E L+
Sbjct: 644 TVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 703
Query: 465 VTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAH-----DPHAHSKALESLRNEVT 517
L G E A A+ V+ LE++ + L H A + +L E T
Sbjct: 704 RQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT 763
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
R R E E + +++ Q L A E++ + + L L + +++ A QE
Sbjct: 764 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQE 823
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQ 604
+ K + + QA+ E +R+Q
Sbjct: 824 KASLDKELMAQKLVQAEREAQASLREQ 850
Score = 53.2 bits (122), Expect = 3e-06
Identities = 114/531 (21%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 96 KIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXX 155
K+DL AQ+ + +S + + ++ + EE+ L E E A +E
Sbjct: 615 KLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVA 674
Query: 156 XXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKD 215
+ + T E L+ ++ L +Q++ + +L +A + Q+ +++
Sbjct: 675 EQAQEALEQQLPTLRHERSQLQ----EQLAQLSRQLSGREQELEQARREAQRQVEALERA 730
Query: 216 MDEL-LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
E A E A V+++ E +T +E+ T+L+ + E +V +L +LE
Sbjct: 731 AREKEALAKEHAGLAVQLVAAEREGRTL-SEEATRLRLEKEALEGSLFEVQRQLAQLEAR 789
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD-AICNKLLLEEQVHQLTSRV 333
R+ Q +++ Q L L E+ LR + ++ A +K L+ +++ Q
Sbjct: 790 RE-----QLEAE-GQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREA 843
Query: 334 EALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXX 393
+A Q HE L ++ + E+ A + L+ E L
Sbjct: 844 QASLREQRAAHEED--LQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKE-- 899
Query: 394 XXXXXXXXHLTEEVATLKYERDKA-----TGKLNDLTTVRKNQESLIHRLQ-KRLLLVTR 447
L+EE+A L+ ERD+ + K L+ + +L +L R L T
Sbjct: 900 --------ELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATI 951
Query: 448 ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSK 507
+ RQ+ D ++ E+ +V L++ + + L+ R+ AA AH++
Sbjct: 952 SLEMERQKRDAQSRQ-------EQDRSTVNALTSEL----RDLRAQREEAAA----AHAQ 996
Query: 508 ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL-----TNNPAA 562
+ L+ + ++ + R+ +LRTQ LL + R G + ++L +
Sbjct: 997 EVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDA--RDGLRRELLEAQRKLRESQEGR 1054
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
E Q+Q + EL + E K + ALR EEL+ ++ E+ RI LK
Sbjct: 1055 EVQRQEAGELRRSLGEGAKEREALRRSN-----EELRSAVKKAESERISLK 1100
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 58.4 bits (135), Expect = 7e-08
Identities = 127/626 (20%), Positives = 252/626 (40%), Gaps = 50/626 (7%)
Query: 14 LEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKR------KSSIGSVDD 67
++ F NT+ D L L + ++ K+ L N L G K + V +
Sbjct: 269 VKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFE 328
Query: 68 VTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILF 127
+ R S G + T +K DL+ K+++T + + Q + + Q
Sbjct: 329 KIQTLKSRAAGSAQGNNQACN--STSEVK-DLLEQKSKLTIEVAELQRQLQLEVKNQQNI 385
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKT-- 185
+EE+ + + ++ + + E +E +K ++ +T
Sbjct: 386 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 445
Query: 186 -DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
DL Q++++ D+L A S + + ++ELLQA + Q + +++ R
Sbjct: 446 RDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAKQDLQDLLIAKEEQEDLLRKRE 502
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLK-----ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ T LK L+++ Q KLK EL+ R+S ++ T++ N +E +
Sbjct: 503 RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSEQD 561
Query: 300 KEVTRLRAN--ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ T +R + LE +V QL ++E L+ + + E K QL
Sbjct: 562 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 621
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E + AR E+ A R ALE+ L L+E++ ++++
Sbjct: 622 EEALVHARKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 677
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCGEEGA 473
N++ R + I +LQK + +V R S + QLD Y+ E+
Sbjct: 678 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK---------EKNR 728
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
+A + +++ EK+L+ + + A + +E + R ++EA R+ +
Sbjct: 729 RELAEMQRQLK--EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLE-- 784
Query: 534 RTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+T +DL L A +++++ + ++ + ++ +E + +++ + RE
Sbjct: 785 QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRS-REQM 843
Query: 591 AQADPEELQQ--MRQQLENSRIKLKR 614
Q E LQ+ RQ LE +I L+R
Sbjct: 844 EQVRNELLQERAARQDLECDKISLER 869
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 725 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA-LTKRQLL 783
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 784 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLSERISRSR 840
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E ++V ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 841 EQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 900
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 901 AELEDRLES 909
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 58.0 bits (134), Expect = 9e-08
Identities = 98/455 (21%), Positives = 195/455 (42%), Gaps = 38/455 (8%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANV--SNKDQISEMKKDMDELLQALEGAQSEVE 231
K+L N KE L + +++++ ++ + + K Q S K+D+D+L+ L + +V
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVN 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQK 290
LK+ L TS EQ + LE+ + +QVT ++ K +E ++QTQ +K
Sbjct: 950 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ---LEK 1006
Query: 291 RLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQLELHEAKVK 349
+L E+EKE L+ ++R ++ +E+Q+ +L + ++Q VQ L A
Sbjct: 1007 KL---MEVEKEKQELQDDKRRAIES------MEQQLSELKKTLSSVQNEVQEALQRASTA 1057
Query: 350 LSSVESQLESWMSAARAHGVESAGALRDAL---ESALGXXXXXXXXXXXXXXXXXHLTEE 406
LS+ + A+ VE+ L + + HL E
Sbjct: 1058 LSNEQQARRDCQEQAKI-AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEET 1116
Query: 407 VATLKYERDKATGKLNDLTTVRKNQES----LIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
+ + + + + K++ S L+K+ L+ + + ++ KE
Sbjct: 1117 TQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1176
Query: 463 -----LTVTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
L V+L EEG +L R + EK + R +A + + + +E L E+
Sbjct: 1177 GVQGPLNVSL-SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL 1235
Query: 517 TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
E++ A R+ ++ + L + V+ TN E ++++ ++L+ Q
Sbjct: 1236 QE-LEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQ 1294
Query: 577 EEIKKLK---VALREGGAQADPEE--LQQMRQQLE 606
+++KL+ + L+E A+ + LQ ++ LE
Sbjct: 1295 AKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1329
Score = 56.8 bits (131), Expect = 2e-07
Identities = 98/525 (18%), Positives = 201/525 (38%), Gaps = 29/525 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD-EF 166
KLE+ V +HT+ + + + + K L + +++ + E
Sbjct: 854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEV 913
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
A++ + K D+ ++ L+ ++Q++++K+ + +E
Sbjct: 914 QVASQSSQRTGKGQPSNKEDVDDLVSQLR--------QTEEQVNDLKERLKTSTSNVEQY 965
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQS 285
Q+ V L++ L K+ E+ + K++ EFQ Q+ KL E+E E+ +D + ++
Sbjct: 966 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA 1025
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-----HQLTSRVEALQPVQ 340
+ ++ ++EL+K ++ ++ + L E+Q Q VEA +
Sbjct: 1026 IESMEQ--QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYE 1083
Query: 341 LE--LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E LH A V+ + S M++ R H E+ L
Sbjct: 1084 RELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
E++ KL+D V +E + L L + ++ + L
Sbjct: 1144 KCVCRCEDLEKQNRLLHDQIEKLSD-KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRF 1202
Query: 459 YEKELTVTLCGEEGAGSVAL-LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+E + E A +L RV+ LE+ LQ D + A A ++E
Sbjct: 1203 IRREKEIAETRFEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEEL 1262
Query: 518 RWREEAEGARRDVTK-LRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK------ 570
+ E + K LR +++ L L+++ + + L L P EA ++S+
Sbjct: 1263 MKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ 1322
Query: 571 -ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E + +E++K+ K + +Q + ++ R+ L + KR
Sbjct: 1323 AEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKR 1367
Score = 48.8 bits (111), Expect = 6e-05
Identities = 84/392 (21%), Positives = 159/392 (40%), Gaps = 15/392 (3%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQT 241
E+T+L+K +++KL + + +I +K ++ E E+E L +
Sbjct: 10 ERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLV 69
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEK 300
+ +C L+ +LEK N + + +T K KELE +D Q+Q ++T ++ +L +
Sbjct: 70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIR 129
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
RL L + + K L E+ T++ E LQ EL + V + E +LE
Sbjct: 130 TNERLSQELEYLTEDV--KRLNEKLKESNTTKGE-LQLKLDELQASDVSVKYREKRLEQE 186
Query: 361 MSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ L+ + L + EEV+ L+ ++ G
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE---EQMNGL 243
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEK--ELTVTLCGEEGAGSVAL 478
++K+ E L+ +L++ + + +L+ + K L + + A S L
Sbjct: 244 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNEL 303
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
A V++L K L+ + A H LE +++ +E E R +L D
Sbjct: 304 TRA-VEELHKLLKEAGEANKAIQDH----LLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Query: 539 LLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
LL+A+ + ++ +P A A +I K
Sbjct: 359 LLSATKRKGAILSEEELAAMSPTAAAVAKIVK 390
Score = 48.4 bits (110), Expect = 7e-05
Identities = 88/469 (18%), Positives = 183/469 (39%), Gaps = 27/469 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E A K+ +++ N+ KEK + K + +KL E + Q +++ +D + E
Sbjct: 667 EAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYE 726
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEYERDSYKD 280
Q VE ++E+ R ++ T + E+ + + KL E ++ K
Sbjct: 727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKK 786
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPV 339
+ K ++ RL + E + R L + + +LE + R+ + ++ +
Sbjct: 787 EKEMLKLSEVRLSQ--QRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKL 844
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ E+ K KL + Q + +++ L L
Sbjct: 845 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATL 904
Query: 400 XXHLTEEVATLKYERDKATGK--------LNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
HL+ + + + TGK ++DL + + E ++ L++RL T +
Sbjct: 905 KQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQ 964
Query: 452 YRQQLDCYEKELT-VTLCGEEGAGSVALL---SARVQ-QLEKSL-QGYRDLIAAHDPHAH 505
Y+ + E+ L EE ++ + SA Q QLEK L + ++ D
Sbjct: 965 YQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD--K 1022
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
+A+ES+ +++ ++ + +V + QR S E+ + A EAQ
Sbjct: 1023 RRAIESMEQQLSELKKTLSSVQNEVQE-ALQRASTALSNEQ--QARRDCQEQAKIAVEAQ 1079
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQAD-PEELQQMRQQLENSRIKLK 613
+ +EL +++ L+ A + A + L++ Q+ E+ ++ K
Sbjct: 1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECK 1128
Score = 40.3 bits (90), Expect = 0.020
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q+ K+ R Q+ K Q E A H+ +V +M++ K+
Sbjct: 1433 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL-----------KE 1481
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
N A + K L++ + + L ++ + ++ L E V + ++S +++D+ + E
Sbjct: 1482 TLNQAETKSKSLESQVENLQKTLSEKETEARN-LQEQTVQLQSELSRLRQDLQDRTTQEE 1540
Query: 225 GAQSEV----EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
+ ++ E +K +V S+ +K+QL K+N E +Q L + + E D
Sbjct: 1541 QLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELD 1596
Score = 35.1 bits (77), Expect = 0.75
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 15/204 (7%)
Query: 78 SSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRV-NHQHTIRKEMQILFEEEKASLIE 136
SSG+ S E + LK L A+ + LES+V N Q T+ ++ E E +L E
Sbjct: 1462 SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK-----ETEARNLQE 1516
Query: 137 QHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKD 196
Q + + +S + + + KE K KA + H +A +KD
Sbjct: 1517 QTVQLQSELSRLRQDLQDRTTQEEQLRQQI--TEKEEKTRKAIVAAKSKIAH--LAGVKD 1572
Query: 197 KLLEANVSNKDQ---ISEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSR-AEQCTQLK 251
+L + N K + + + K ++D + AL+ + + L++EL + R EQ + +
Sbjct: 1573 QLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQ 1632
Query: 252 NQLEKQNFEFQQVTSKLKELEYER 275
K + +Q+T K ER
Sbjct: 1633 EPSNKVPEQQRQITLKTTPASGER 1656
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/108 (21%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
++ +SLR E+ + + + +L +D A + + L
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN 131
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+++S+ELE E++K+L L+E + ELQ +L+ S + +K
Sbjct: 132 ERLSQELEYLTEDVKRLNEKLKE--SNTTKGELQLKLDELQASDVSVK 177
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 58.0 bits (134), Expect = 9e-08
Identities = 100/458 (21%), Positives = 194/458 (42%), Gaps = 44/458 (9%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANV--SNKDQISEMKKDMDELLQALEGAQSEVE 231
K+L N KE L + +++++ ++ + + K Q S K+D+D+L+ L + +V
Sbjct: 891 KELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVN 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQK 290
LK+ L TS EQ + LE+ + +QVT ++ K +E ++QTQ +K
Sbjct: 950 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ---LEK 1006
Query: 291 RLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQLELHEAKVK 349
+L E+EKE L+ ++R ++ +E+Q+ +L + ++Q VQ L A
Sbjct: 1007 KL---MEVEKEKQELQDDKRRAIES------MEQQLSELKKTLSSVQNEVQEALQRASTA 1057
Query: 350 LSSVESQLESWMSAARAHGVESAGALRDAL---ESALGXXXXXXXXXXXXXXXXXHLTEE 406
LS+ + A+ VE+ L + + HL E
Sbjct: 1058 LSNEQQARRDCQEQAKI-AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEET 1116
Query: 407 VATLKYERDKATGKLNDLTTVRKNQES----LIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
+ + + + + K++ S L+K+ L+ + + ++ KE
Sbjct: 1117 TQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1176
Query: 463 -----LTVTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
L V+L EEG +L R + EK + R +A + + + +E L E+
Sbjct: 1177 GVQGPLNVSL-SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL 1235
Query: 517 TRWREEAEGARRDV---TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
++ R V K Q + L E + V+ TN E ++++ ++L+
Sbjct: 1236 QELQDSLNAEREKVQVTAKTMAQHEELMKKTETM----NVVMETNKMLREEKERLEQDLQ 1291
Query: 574 AAQEEIKKLK---VALREGGAQADPEE--LQQMRQQLE 606
Q +++KL+ + L+E A+ + LQ ++ LE
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1329
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/525 (18%), Positives = 202/525 (38%), Gaps = 29/525 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD-EF 166
KLE+ V +HT+ + + + + K L + +++ + E
Sbjct: 854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEV 913
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
A++ + K D+ ++ L+ ++Q++++K+ + +E
Sbjct: 914 QVASQSSQRTGKGQPSNKEDVDDLVSQLR--------QTEEQVNDLKERLKTSTSNVEQY 965
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQS 285
Q+ V L++ L K+ E+ + K++ EFQ Q+ KL E+E E+ +D + ++
Sbjct: 966 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA 1025
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-----HQLTSRVEALQPVQ 340
+ ++ ++EL+K ++ ++ + L E+Q Q VEA +
Sbjct: 1026 IESMEQ--QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYE 1083
Query: 341 LE--LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E LH A V+ + S M++ R H E+ L
Sbjct: 1084 RELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
E++ KL+D V +E + L L + ++ + L
Sbjct: 1144 KCVCRCEDLEKQNRLLHDQIEKLSD-KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRF 1202
Query: 459 YEKELTVTLCGEEGAGSVAL-LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+E + E A +L RV+ LE+ LQ +D + A A ++E
Sbjct: 1203 IRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEEL 1262
Query: 518 RWREEAEGARRDVTK-LRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK------ 570
+ E + K LR +++ L L+++ + + L L P EA ++S+
Sbjct: 1263 MKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ 1322
Query: 571 -ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E + +E++K+ K + +Q + ++ R+ L + KR
Sbjct: 1323 AEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKR 1367
Score = 48.8 bits (111), Expect = 6e-05
Identities = 84/392 (21%), Positives = 159/392 (40%), Gaps = 15/392 (3%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQT 241
E+T+L+K +++KL + + +I +K ++ E E+E L +
Sbjct: 10 ERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLV 69
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEK 300
+ +C L+ +LEK N + + +T K KELE +D Q+Q ++T ++ +L +
Sbjct: 70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIR 129
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
RL L + + K L E+ T++ E LQ EL + V + E +LE
Sbjct: 130 TNERLSQELEYLTEDV--KRLNEKLKESNTTKGE-LQLKLDELQASDVSVKYREKRLEQE 186
Query: 361 MSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ L+ + L + EEV+ L+ ++ G
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE---EQMNGL 243
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEK--ELTVTLCGEEGAGSVAL 478
++K+ E L+ +L++ + + +L+ + K L + + A S L
Sbjct: 244 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNEL 303
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
A V++L K L+ + A H LE +++ +E E R +L D
Sbjct: 304 TRA-VEELHKLLKEAGEANKAIQDH----LLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Query: 539 LLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
LL+A+ + ++ +P A A +I K
Sbjct: 359 LLSATKRKGAILSEEELAAMSPTAAAVAKIVK 390
Score = 48.4 bits (110), Expect = 7e-05
Identities = 88/469 (18%), Positives = 183/469 (39%), Gaps = 27/469 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E A K+ +++ N+ KEK + K + +KL E + Q +++ +D + E
Sbjct: 667 EAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYE 726
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEYERDSYKD 280
Q VE ++E+ R ++ T + E+ + + KL E ++ K
Sbjct: 727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKK 786
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPV 339
+ K ++ RL + E + R L + + +LE + R+ + ++ +
Sbjct: 787 EKEMLKLSEVRLSQ--QRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKL 844
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ E+ K KL + Q + +++ L L
Sbjct: 845 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATL 904
Query: 400 XXHLTEEVATLKYERDKATGK--------LNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
HL+ + + + TGK ++DL + + E ++ L++RL T +
Sbjct: 905 KRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQ 964
Query: 452 YRQQLDCYEKELT-VTLCGEEGAGSVALL---SARVQ-QLEKSL-QGYRDLIAAHDPHAH 505
Y+ + E+ L EE ++ + SA Q QLEK L + ++ D
Sbjct: 965 YQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD--K 1022
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
+A+ES+ +++ ++ + +V + QR S E+ + A EAQ
Sbjct: 1023 RRAIESMEQQLSELKKTLSSVQNEVQE-ALQRASTALSNEQ--QARRDCQEQAKIAVEAQ 1079
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQAD-PEELQQMRQQLENSRIKLK 613
+ +EL +++ L+ A + A + L++ Q+ E+ ++ K
Sbjct: 1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECK 1128
Score = 40.3 bits (90), Expect = 0.020
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q+ K+ R Q+ K Q E A H+ +V +M++ K+
Sbjct: 1433 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL-----------KE 1481
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
N A + K L++ + + L ++ + ++ L E V + ++S +++D+ + E
Sbjct: 1482 TLNQAETKSKSLESQVENLQKTLSEKETEARN-LQEQTVQLQSELSRLRQDLQDRTTQEE 1540
Query: 225 GAQSEV----EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
+ ++ E +K +V S+ +K+QL K+N E +Q L + + E D
Sbjct: 1541 QLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELD 1596
Score = 35.1 bits (77), Expect = 0.75
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 15/204 (7%)
Query: 78 SSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRV-NHQHTIRKEMQILFEEEKASLIE 136
SSG+ S E + LK L A+ + LES+V N Q T+ ++ E E +L E
Sbjct: 1462 SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK-----ETEARNLQE 1516
Query: 137 QHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKD 196
Q + + +S + + + KE K KA + H +A +KD
Sbjct: 1517 QTVQLQSELSRLRQDLQDRTTQEEQLRQQI--TEKEEKTRKAIVAAKSKIAH--LAGVKD 1572
Query: 197 KLLEANVSNKDQ---ISEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSR-AEQCTQLK 251
+L + N K + + + K ++D + AL+ + + L++EL + R EQ + +
Sbjct: 1573 QLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQ 1632
Query: 252 NQLEKQNFEFQQVTSKLKELEYER 275
K + +Q+T K ER
Sbjct: 1633 EPSNKVPEQQRQITLKTTPASGER 1656
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/108 (21%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
++ +SLR E+ + + + +L +D A + + L
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN 131
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+++S+ELE E++K+L L+E + ELQ +L+ S + +K
Sbjct: 132 ERLSQELEYLTEDVKRLNEKLKE--SNTTKGELQLKLDELQASDVSVK 177
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 9e-08
Identities = 127/626 (20%), Positives = 252/626 (40%), Gaps = 50/626 (7%)
Query: 14 LEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKR------KSSIGSVDD 67
++ F NT+ D L L + ++ K+ L N L G K + V +
Sbjct: 524 VKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFE 583
Query: 68 VTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILF 127
+ R S G + T +K DL+ K+++T + + Q + + Q
Sbjct: 584 KIQTLKSRAAGSAQGNNQACN--STSEVK-DLLEQKSKLTIEVAELQRQLQLEVKNQQNI 640
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKT-- 185
+EE+ + + ++ + + E +E +K ++ +T
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 186 -DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
DL Q++++ D+L A S + + ++ELLQA + Q + +++ R
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAKQDLQDLLIAKEEQEDLLRKRE 757
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLK-----ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ T LK L+++ Q KLK EL+ R+S ++ T++ N +E +
Sbjct: 758 RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSEQD 816
Query: 300 KEVTRLRAN--ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ T +R + LE +V QL ++E L+ + + E K QL
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E + AR E+ A R ALE+ L L+E++ ++++
Sbjct: 877 EEALVHARKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCGEEGA 473
N++ R + I +LQK + +V R S + QLD Y+ E+
Sbjct: 933 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK---------EKNR 983
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
+A + +++ EK+L+ + + A + +E + R ++EA R+ +
Sbjct: 984 RELAEMQRQLK--EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLE-- 1039
Query: 534 RTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+T +DL L A +++++ + ++ + ++ +E + +++ + RE
Sbjct: 1040 QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRS-REQM 1098
Query: 591 AQADPEELQQ--MRQQLENSRIKLKR 614
Q E LQ+ RQ LE +I L+R
Sbjct: 1099 EQLRNELLQERAARQDLECDKISLER 1124
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 980 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA-LTKRQLL 1038
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 1039 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLSERISRSR 1095
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E +++ ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 1096 EQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 1155
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 1156 AELEDRLES 1164
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 9e-08
Identities = 127/626 (20%), Positives = 252/626 (40%), Gaps = 50/626 (7%)
Query: 14 LEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKR------KSSIGSVDD 67
++ F NT+ D L L + ++ K+ L N L G K + V +
Sbjct: 524 VKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFE 583
Query: 68 VTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILF 127
+ R S G + T +K DL+ K+++T + + Q + + Q
Sbjct: 584 KIQTLKSRAAGSAQGNNQACN--STSEVK-DLLEQKSKLTIEVAELQRQLQLEVKNQQNI 640
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKT-- 185
+EE+ + + ++ + + E +E +K ++ +T
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 186 -DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
DL Q++++ D+L A S + + ++ELLQA + Q + +++ R
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAKQDLQDLLIAKEEQEDLLRKRE 757
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLK-----ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ T LK L+++ Q KLK EL+ R+S ++ T++ N +E +
Sbjct: 758 RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSEQD 816
Query: 300 KEVTRLRAN--ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ T +R + LE +V QL ++E L+ + + E K QL
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E + AR E+ A R ALE+ L L+E++ ++++
Sbjct: 877 EEALVHARKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCGEEGA 473
N++ R + I +LQK + +V R S + QLD Y+ E+
Sbjct: 933 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK---------EKNR 983
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
+A + +++ EK+L+ + + A + +E + R ++EA R+ +
Sbjct: 984 RELAEMQRQLK--EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLE-- 1039
Query: 534 RTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+T +DL L A +++++ + ++ + ++ +E + +++ + RE
Sbjct: 1040 QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRS-REQM 1098
Query: 591 AQADPEELQQ--MRQQLENSRIKLKR 614
Q E LQ+ RQ LE +I L+R
Sbjct: 1099 EQLRNELLQERAARQDLECDKISLER 1124
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 980 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA-LTKRQLL 1038
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 1039 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLSERISRSR 1095
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E +++ ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 1096 EQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 1155
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 1156 AELEDRLES 1164
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 9e-08
Identities = 127/626 (20%), Positives = 252/626 (40%), Gaps = 50/626 (7%)
Query: 14 LEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKR------KSSIGSVDD 67
++ F NT+ D L L + ++ K+ L N L G K + V +
Sbjct: 524 VKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFE 583
Query: 68 VTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILF 127
+ R S G + T +K DL+ K+++T + + Q + + Q
Sbjct: 584 KIQTLKSRAAGSAQGNNQACN--STSEVK-DLLEQKSKLTIEVAELQRQLQLEVKNQQNI 640
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKT-- 185
+EE+ + + ++ + + E +E +K ++ +T
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 186 -DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
DL Q++++ D+L A S + + ++ELLQA + Q + +++ R
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAKQDLQDLLIAKEEQEDLLRKRE 757
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLK-----ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ T LK L+++ Q KLK EL+ R+S ++ T++ N +E +
Sbjct: 758 RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSEQD 816
Query: 300 KEVTRLRAN--ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ T +R + LE +V QL ++E L+ + + E K QL
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E + AR E+ A R ALE+ L L+E++ ++++
Sbjct: 877 EEALVHARKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCGEEGA 473
N++ R + I +LQK + +V R S + QLD Y+ E+
Sbjct: 933 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK---------EKNR 983
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
+A + +++ EK+L+ + + A + +E + R ++EA R+ +
Sbjct: 984 RELAEMQRQLK--EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLE-- 1039
Query: 534 RTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+T +DL L A +++++ + ++ + ++ +E + +++ + RE
Sbjct: 1040 QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRS-REQM 1098
Query: 591 AQADPEELQQ--MRQQLENSRIKLKR 614
Q E LQ+ RQ LE +I L+R
Sbjct: 1099 EQLRNELLQERAARQDLECDKISLER 1124
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 980 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA-LTKRQLL 1038
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 1039 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLSERISRSR 1095
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E +++ ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 1096 EQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 1155
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 1156 AELEDRLES 1164
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 58.0 bits (134), Expect = 9e-08
Identities = 127/626 (20%), Positives = 252/626 (40%), Gaps = 50/626 (7%)
Query: 14 LEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKR------KSSIGSVDD 67
++ F NT+ D L L + ++ K+ L N L G K + V +
Sbjct: 524 VKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFE 583
Query: 68 VTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILF 127
+ R S G + T +K DL+ K+++T + + Q + + Q
Sbjct: 584 KIQTLKSRAAGSAQGNNQACN--STSEVK-DLLEQKSKLTIEVAELQRQLQLEVKNQQNI 640
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKT-- 185
+EE+ + + ++ + + E +E +K ++ +T
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 186 -DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
DL Q++++ D+L A S + + ++ELLQA + Q + +++ R
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAKQDLQDLLIAKEEQEDLLRKRE 757
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLK-----ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ T LK L+++ Q KLK EL+ R+S ++ T++ N +E +
Sbjct: 758 RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSEQD 816
Query: 300 KEVTRLRAN--ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ T +R + LE +V QL ++E L+ + + E K QL
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
E + AR E+ A R ALE+ L L+E++ ++++
Sbjct: 877 EEALVHARKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQKEQL 932
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCGEEGA 473
N++ R + I +LQK + +V R S + QLD Y+ E+
Sbjct: 933 RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK---------EKNR 983
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
+A + +++ EK+L+ + + A + +E + R ++EA R+ +
Sbjct: 984 RELAEMQRQLK--EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLE-- 1039
Query: 534 RTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGG 590
+T +DL L A +++++ + ++ + ++ +E + +++ + RE
Sbjct: 1040 QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRS-REQM 1098
Query: 591 AQADPEELQQ--MRQQLENSRIKLKR 614
Q E LQ+ RQ LE +I L+R
Sbjct: 1099 EQLRNELLQERAARQDLECDKISLER 1124
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 980 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA-LTKRQLL 1038
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 1039 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLSERISRSR 1095
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E +++ ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 1096 EQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 1155
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 1156 AELEDRLES 1164
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 58.0 bits (134), Expect = 9e-08
Identities = 114/514 (22%), Positives = 210/514 (40%), Gaps = 53/514 (10%)
Query: 120 RKEMQILFEEEKASL--IEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK 177
RK Q+L EE+ A L +E+ +R E + E ++ ++++ L+
Sbjct: 18 RKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALR 77
Query: 178 ANWD---KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLK 234
A + K D+ K + +L+ A + D +++ + DEL A E A+ +E+
Sbjct: 78 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAA-EDAKLRLEVTV 136
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
+ L Q R L+ + E +Q+ +L++ E ERD + +T + A+K+L
Sbjct: 137 QALKTQHER-----DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL-- 189
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
E E+ L+A S EE V QL ++ + E+ E + +
Sbjct: 190 ----EGELEELKAQMASAGQG------KEEAVKQLRKMQAQMKELWREVEETRTSREEIF 239
Query: 355 SQLESWMSAARAHGVESAGA-LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYE 413
SQ S R G+E+ L++ L ++ + A + E
Sbjct: 240 SQNRE--SEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 297
Query: 414 RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA 473
+ + G+L L + ++S LL D YR+ L E LT L E
Sbjct: 298 KRQLEGRLGQLEEELEEEQS-----NSELL-----NDRYRKLLLQVES-LTTELSAERSF 346
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHA---HSKALESLRNEVTRWREEAEGARRDV 530
+ A S R QQLE+ +Q R + D A H + +L +++ + E+ E R+
Sbjct: 347 SAKAE-SGR-QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRER 404
Query: 531 T---KL--RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ---KQISKELEAAQEEIKKL 582
KL R ++ L L+ + + +V + + KQ+ ++LE A+EE +
Sbjct: 405 ILSGKLVRRAEKRLKEVVLQ-VEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 463
Query: 583 KVALREGGAQAD--PEELQQMRQQLENSRIKLKR 614
+ R + + E + M +++ R +L+R
Sbjct: 464 QAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 497
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 58.0 bits (134), Expect = 9e-08
Identities = 111/558 (19%), Positives = 228/558 (40%), Gaps = 50/558 (8%)
Query: 93 KRLKIDLIAAKAQITKLESRVN-HQHTIRKEMQILFEE-EKASLIEQHKRDERAVSDMED 150
++L++ + +IT L+ + T +KE++ L+ EK S K +E S +E
Sbjct: 297 EKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLS-----KENESLKSKLEH 351
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
K + TA H+ +LK ++ K + A+LK ++ + + +
Sbjct: 352 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQ 411
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ-LKNQLEKQN----FEF 261
+I ++ D A E+E L+ +L+K E + ++++L+K E
Sbjct: 412 HEIENLQNQQDSERAA---HAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 468
Query: 262 QQVTSKLKELEYERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAIC 317
+ +KL+E E +++ + + ++ ++ Q+ + + + E++ L ++ LR+ +
Sbjct: 469 EDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLA 528
Query: 318 N-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
+ + E+ + ++A + ++ ++ E SQL R L+
Sbjct: 529 DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQ 587
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESL 434
L A +++ A K+E +K KL+DL + +
Sbjct: 588 LKLTKA-NENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 646
Query: 435 IHRLQKRLLLVTRE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEK 488
L+ R T E + + + L +K L T L G EE +G + L +Q EK
Sbjct: 647 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 706
Query: 489 S--LQGYRDLIAAHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQR 537
+ Q D + + K +LE + + + E + + ++V +L +
Sbjct: 707 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSK 766
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPE 596
+LLT +++ K + AA Q S++L A QEE KL L R +
Sbjct: 767 ELLTVENQKMEEFRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQ 822
Query: 597 ELQQMRQQLENSRIKLKR 614
+L++ R L N +++K+
Sbjct: 823 KLEEERSVLNNQLLEMKK 840
Score = 31.9 bits (69), Expect = 6.9
Identities = 86/458 (18%), Positives = 186/458 (40%), Gaps = 42/458 (9%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
+E L+ + +TD ++I LK+ +++ +I + ++L + E +S++
Sbjct: 290 QEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL 349
Query: 231 EMLKKE----LVKQTSRAEQCTQLKNQ-LEKQNFEFQQ----VTSKLKELEYERDSYK-D 280
E KE + S+ E Q +E+ F + T++ EL+ + + + D
Sbjct: 350 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD 409
Query: 281 WQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
+Q + + Q + A KE+ LRA L I K E + + S+++ +
Sbjct: 410 YQHEIENLQNQQDSERAAHAKEMEALRA---KLMKVIKEK---ENSLEAIRSKLDKAEDQ 463
Query: 340 QL-ELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
L E+ + KL E + E + A+ E A +++ +++ +
Sbjct: 464 HLVEMEDTLNKLQEAEIKKEKFAEAS-----EEAVSVQRSMQETVNKLHQKEEQFNMLSS 518
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK----RLLLVTRERDSYR- 453
L E +A ++ + + + L ++ E+ I + K +T+ D R
Sbjct: 519 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 578
Query: 454 QQLDCYEKELTVTLCGEEGAGSVALLSARVQQLE-KSLQGYRDLIAAHDPHAHSKALESL 512
++ D E +L +T E + + L ++ + K+ Q ++ H+ K LE
Sbjct: 579 KERDVEELQLKLTKANE----NASFLQKSIEDMTVKAEQSQQEAAKKHE--EEKKELERK 632
Query: 513 RNEVTRWREEAEGARRDVTKLRTQR---DLLTASLERIGPQTKVLHLTNNP---AAEAQK 566
+++ + E + +++ K R +R + T E + K L T + A E
Sbjct: 633 LSDLEKKMETSHNQCQEL-KARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENS 691
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
+ +ELE +++ +K K A A E++ + + +
Sbjct: 692 GLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTE 729
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 57.6 bits (133), Expect = 1e-07
Identities = 100/458 (21%), Positives = 194/458 (42%), Gaps = 44/458 (9%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANV--SNKDQISEMKKDMDELLQALEGAQSEVE 231
K+L N KE L + +++++ ++ + + K Q S K+D+D+L+ L + +V
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVN 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQK 290
LK+ L TS EQ + LE+ + +QVT ++ K +E ++QTQ +K
Sbjct: 950 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ---LEK 1006
Query: 291 RLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQLELHEAKVK 349
+L E+EKE L+ ++R ++ +E+Q+ +L + ++Q VQ L A
Sbjct: 1007 KL---MEVEKEKQELQDDKRRAIES------MEQQLSELKKTLSSVQNEVQEALQRASTA 1057
Query: 350 LSSVESQLESWMSAARAHGVESAGALRDAL---ESALGXXXXXXXXXXXXXXXXXHLTEE 406
LS+ + A+ VE+ L + + HL E
Sbjct: 1058 LSNEQQARRDCQEQAKI-AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEET 1116
Query: 407 VATLKYERDKATGKLNDLTTVRKNQES----LIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
+ + + + + K++ S L+K+ L+ + + ++ KE
Sbjct: 1117 TQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1176
Query: 463 -----LTVTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
L V+L EEG +L R + EK + R +A + + + +E L E+
Sbjct: 1177 GVQGPLNVSL-SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL 1235
Query: 517 TRWREEAEGARRDV---TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
++ R V K Q + L E + V+ TN E ++++ ++L+
Sbjct: 1236 QELQDSLNAEREKVQVTAKTMAQHEELMKKTETM----NVVMETNKMLREEKERLEQDLQ 1291
Query: 574 AAQEEIKKLK---VALREGGAQADPEE--LQQMRQQLE 606
Q +++KL+ + L+E A+ + LQ ++ LE
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1329
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/525 (18%), Positives = 202/525 (38%), Gaps = 29/525 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD-EF 166
KLE+ V +HT+ + + + + K L + +++ + E
Sbjct: 854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEV 913
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
A++ + K D+ ++ L+ ++Q++++K+ + +E
Sbjct: 914 QVASQSSQRTGKGQPSNKEDVDDLVSQLR--------QTEEQVNDLKERLKTSTSNVEQY 965
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQS 285
Q+ V L++ L K+ E+ + K++ EFQ Q+ KL E+E E+ +D + ++
Sbjct: 966 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA 1025
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-----HQLTSRVEALQPVQ 340
+ ++ ++EL+K ++ ++ + L E+Q Q VEA +
Sbjct: 1026 IESMEQ--QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYE 1083
Query: 341 LE--LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E LH A V+ + S M++ R H E+ L
Sbjct: 1084 RELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
E++ KL+D V +E + L L + ++ + L
Sbjct: 1144 KCVCRCEDLEKQNRLLHDQIEKLSD-KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRF 1202
Query: 459 YEKELTVTLCGEEGAGSVAL-LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+E + E A +L RV+ LE+ LQ +D + A A ++E
Sbjct: 1203 IRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEEL 1262
Query: 518 RWREEAEGARRDVTK-LRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK------ 570
+ E + K LR +++ L L+++ + + L L P EA ++S+
Sbjct: 1263 MKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ 1322
Query: 571 -ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E + +E++K+ K + +Q + ++ R+ L + KR
Sbjct: 1323 AEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKR 1367
Score = 48.8 bits (111), Expect = 6e-05
Identities = 84/392 (21%), Positives = 159/392 (40%), Gaps = 15/392 (3%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQT 241
E+T+L+K +++KL + + +I +K ++ E E+E L +
Sbjct: 10 ERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLV 69
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEK 300
+ +C L+ +LEK N + + +T K KELE +D Q+Q ++T ++ +L +
Sbjct: 70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIR 129
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
RL L + + K L E+ T++ E LQ EL + V + E +LE
Sbjct: 130 TNERLSQELEYLTEDV--KRLNEKLKESNTTKGE-LQLKLDELQASDVSVKYREKRLEQE 186
Query: 361 MSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ L+ + L + EEV+ L+ ++ G
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE---EQMNGL 243
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEK--ELTVTLCGEEGAGSVAL 478
++K+ E L+ +L++ + + +L+ + K L + + A S L
Sbjct: 244 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNEL 303
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
A V++L K L+ + A H LE +++ +E E R +L D
Sbjct: 304 TRA-VEELHKLLKEAGEANKAIQDH----LLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Query: 539 LLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
LL+A+ + ++ +P A A +I K
Sbjct: 359 LLSATKRKGAILSEEELAAMSPTAAAVAKIVK 390
Score = 48.4 bits (110), Expect = 7e-05
Identities = 88/469 (18%), Positives = 183/469 (39%), Gaps = 27/469 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E A K+ +++ N+ KEK + K + +KL E + Q +++ +D + E
Sbjct: 667 EAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYE 726
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEYERDSYKD 280
Q VE ++E+ R ++ T + E+ + + KL E ++ K
Sbjct: 727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKK 786
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPV 339
+ K ++ RL + E + R L + + +LE + R+ + ++ +
Sbjct: 787 EKEMLKLSEVRLSQ--QRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKL 844
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ E+ K KL + Q + +++ L L
Sbjct: 845 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATL 904
Query: 400 XXHLTEEVATLKYERDKATGK--------LNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
HL+ + + + TGK ++DL + + E ++ L++RL T +
Sbjct: 905 KQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQ 964
Query: 452 YRQQLDCYEKELT-VTLCGEEGAGSVALL---SARVQ-QLEKSL-QGYRDLIAAHDPHAH 505
Y+ + E+ L EE ++ + SA Q QLEK L + ++ D
Sbjct: 965 YQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD--K 1022
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
+A+ES+ +++ ++ + +V + QR S E+ + A EAQ
Sbjct: 1023 RRAIESMEQQLSELKKTLSSVQNEVQE-ALQRASTALSNEQ--QARRDCQEQAKIAVEAQ 1079
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQAD-PEELQQMRQQLENSRIKLK 613
+ +EL +++ L+ A + A + L++ Q+ E+ ++ K
Sbjct: 1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECK 1128
Score = 40.3 bits (90), Expect = 0.020
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q+ K+ R Q+ K Q E A H+ +V +M++ K+
Sbjct: 1433 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL-----------KE 1481
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
N A + K L++ + + L ++ + ++ L E V + ++S +++D+ + E
Sbjct: 1482 TLNQAETKSKSLESQVENLQKTLSEKETEARN-LQEQTVQLQSELSRLRQDLQDRTTQEE 1540
Query: 225 GAQSEV----EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
+ ++ E +K +V S+ +K+QL K+N E +Q L + + E D
Sbjct: 1541 QLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELD 1596
Score = 35.1 bits (77), Expect = 0.75
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 15/204 (7%)
Query: 78 SSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRV-NHQHTIRKEMQILFEEEKASLIE 136
SSG+ S E + LK L A+ + LES+V N Q T+ ++ E E +L E
Sbjct: 1462 SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK-----ETEARNLQE 1516
Query: 137 QHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKD 196
Q + + +S + + + KE K KA + H +A +KD
Sbjct: 1517 QTVQLQSELSRLRQDLQDRTTQEEQLRQQI--TEKEEKTRKAIVAAKSKIAH--LAGVKD 1572
Query: 197 KLLEANVSNKDQ---ISEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSR-AEQCTQLK 251
+L + N K + + + K ++D + AL+ + + L++EL + R EQ + +
Sbjct: 1573 QLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQ 1632
Query: 252 NQLEKQNFEFQQVTSKLKELEYER 275
K + +Q+T K ER
Sbjct: 1633 EPSNKVPEQQRQITLKTTPASGER 1656
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/108 (21%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
++ +SLR E+ + + + +L +D A + + L
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN 131
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+++S+ELE E++K+L L+E + ELQ +L+ S + +K
Sbjct: 132 ERLSQELEYLTEDVKRLNEKLKE--SNTTKGELQLKLDELQASDVSVK 177
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 57.6 bits (133), Expect = 1e-07
Identities = 100/458 (21%), Positives = 194/458 (42%), Gaps = 44/458 (9%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANV--SNKDQISEMKKDMDELLQALEGAQSEVE 231
K+L N KE L + +++++ ++ + + K Q S K+D+D+L+ L + +V
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSN-KEDVDDLVSQLRQTEEQVN 949
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQK 290
LK+ L TS EQ + LE+ + +QVT ++ K +E ++QTQ +K
Sbjct: 950 DLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQ---LEK 1006
Query: 291 RLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQLELHEAKVK 349
+L E+EKE L+ ++R ++ +E+Q+ +L + ++Q VQ L A
Sbjct: 1007 KL---MEVEKEKQELQDDKRRAIES------MEQQLSELKKTLSSVQNEVQEALQRASTA 1057
Query: 350 LSSVESQLESWMSAARAHGVESAGALRDAL---ESALGXXXXXXXXXXXXXXXXXHLTEE 406
LS+ + A+ VE+ L + + HL E
Sbjct: 1058 LSNEQQARRDCQEQAKI-AVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEET 1116
Query: 407 VATLKYERDKATGKLNDLTTVRKNQES----LIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
+ + + + + K++ S L+K+ L+ + + ++ KE
Sbjct: 1117 TQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKE 1176
Query: 463 -----LTVTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
L V+L EEG +L R + EK + R +A + + + +E L E+
Sbjct: 1177 GVQGPLNVSL-SEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLEREL 1235
Query: 517 TRWREEAEGARRDV---TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
++ R V K Q + L E + V+ TN E ++++ ++L+
Sbjct: 1236 QELQDSLNAEREKVQVTAKTMAQHEELMKKTETM----NVVMETNKMLREEKERLEQDLQ 1291
Query: 574 AAQEEIKKLK---VALREGGAQADPEE--LQQMRQQLE 606
Q +++KL+ + L+E A+ + LQ ++ LE
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE 1329
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/525 (18%), Positives = 202/525 (38%), Gaps = 29/525 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD-EF 166
KLE+ V +HT+ + + + + K L + +++ + E
Sbjct: 854 KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEV 913
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
A++ + K D+ ++ L+ ++Q++++K+ + +E
Sbjct: 914 QVASQSSQRTGKGQPSNKEDVDDLVSQLR--------QTEEQVNDLKERLKTSTSNVEQY 965
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQS 285
Q+ V L++ L K+ E+ + K++ EFQ Q+ KL E+E E+ +D + ++
Sbjct: 966 QAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRA 1025
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-----HQLTSRVEALQPVQ 340
+ ++ ++EL+K ++ ++ + L E+Q Q VEA +
Sbjct: 1026 IESMEQ--QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYE 1083
Query: 341 LE--LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E LH A V+ + S M++ R H E+ L
Sbjct: 1084 RELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVS 1143
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
E++ KL+D V +E + L L + ++ + L
Sbjct: 1144 KCVCRCEDLEKQNRLLHDQIEKLSD-KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRF 1202
Query: 459 YEKELTVTLCGEEGAGSVAL-LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+E + E A +L RV+ LE+ LQ +D + A A ++E
Sbjct: 1203 IRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEEL 1262
Query: 518 RWREEAEGARRDVTK-LRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK------ 570
+ E + K LR +++ L L+++ + + L L P EA ++S+
Sbjct: 1263 MKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQ 1322
Query: 571 -ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E + +E++K+ K + +Q + ++ R+ L + KR
Sbjct: 1323 AEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKR 1367
Score = 48.8 bits (111), Expect = 6e-05
Identities = 84/392 (21%), Positives = 159/392 (40%), Gaps = 15/392 (3%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQT 241
E+T+L+K +++KL + + +I +K ++ E E+E L +
Sbjct: 10 ERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLV 69
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEK 300
+ +C L+ +LEK N + + +T K KELE +D Q+Q ++T ++ +L +
Sbjct: 70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIR 129
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
RL L + + K L E+ T++ E LQ EL + V + E +LE
Sbjct: 130 TNERLSQELEYLTEDV--KRLNEKLKESNTTKGE-LQLKLDELQASDVSVKYREKRLEQE 186
Query: 361 MSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ L+ + L + EEV+ L+ ++ G
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLE---EQMNGL 243
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEK--ELTVTLCGEEGAGSVAL 478
++K+ E L+ +L++ + + +L+ + K L + + A S L
Sbjct: 244 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNEL 303
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
A V++L K L+ + A H LE +++ +E E R +L D
Sbjct: 304 TRA-VEELHKLLKEAGEANKAIQDH----LLEVEQSKDQMEKEMLEKIGRLEKELENAND 358
Query: 539 LLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
LL+A+ + ++ +P A A +I K
Sbjct: 359 LLSATKRKGAILSEEELAAMSPTAAAVAKIVK 390
Score = 48.4 bits (110), Expect = 7e-05
Identities = 88/469 (18%), Positives = 183/469 (39%), Gaps = 27/469 (5%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E A K+ +++ N+ KEK + K + +KL E + Q +++ +D + E
Sbjct: 667 EAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYE 726
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEYERDSYKD 280
Q VE ++E+ R ++ T + E+ + + KL E ++ K
Sbjct: 727 MLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKK 786
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPV 339
+ K ++ RL + E + R L + + +LE + R+ + ++ +
Sbjct: 787 EKEMLKLSEVRLSQ--QRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKL 844
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ E+ K KL + Q + +++ L L
Sbjct: 845 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATL 904
Query: 400 XXHLTEEVATLKYERDKATGK--------LNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
HL+ + + + TGK ++DL + + E ++ L++RL T +
Sbjct: 905 KQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQ 964
Query: 452 YRQQLDCYEKELT-VTLCGEEGAGSVALL---SARVQ-QLEKSL-QGYRDLIAAHDPHAH 505
Y+ + E+ L EE ++ + SA Q QLEK L + ++ D
Sbjct: 965 YQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD--K 1022
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
+A+ES+ +++ ++ + +V + QR S E+ + A EAQ
Sbjct: 1023 RRAIESMEQQLSELKKTLSSVQNEVQE-ALQRASTALSNEQ--QARRDCQEQAKIAVEAQ 1079
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQAD-PEELQQMRQQLENSRIKLK 613
+ +EL +++ L+ A + A + L++ Q+ E+ ++ K
Sbjct: 1080 NKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECK 1128
Score = 40.3 bits (90), Expect = 0.020
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q+ K+ R Q+ K Q E A H+ +V +M++ K+
Sbjct: 1433 QVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL-----------KE 1481
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
N A + K L++ + + L ++ + ++ L E V + ++S +++D+ + E
Sbjct: 1482 TLNQAETKSKSLESQVENLQKTLSEKETEARN-LQEQTVQLQSELSRLRQDLQDRTTQEE 1540
Query: 225 GAQSEV----EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
+ ++ E +K +V S+ +K+QL K+N E +Q L + + E D
Sbjct: 1541 QLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELD 1596
Score = 35.1 bits (77), Expect = 0.75
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 15/204 (7%)
Query: 78 SSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRV-NHQHTIRKEMQILFEEEKASLIE 136
SSG+ S E + LK L A+ + LES+V N Q T+ ++ E E +L E
Sbjct: 1462 SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEK-----ETEARNLQE 1516
Query: 137 QHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKD 196
Q + + +S + + + KE K KA + H +A +KD
Sbjct: 1517 QTVQLQSELSRLRQDLQDRTTQEEQLRQQI--TEKEEKTRKAIVAAKSKIAH--LAGVKD 1572
Query: 197 KLLEANVSNKDQ---ISEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSR-AEQCTQLK 251
+L + N K + + + K ++D + AL+ + + L++EL + R EQ + +
Sbjct: 1573 QLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQRDEPQ 1632
Query: 252 NQLEKQNFEFQQVTSKLKELEYER 275
K + +Q+T K ER
Sbjct: 1633 EPSNKVPEQQRQITLKTTPASGER 1656
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/108 (21%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 506 SKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQ 565
++ +SLR E+ + + + +L +D A + + L
Sbjct: 72 TRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTN 131
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+++S+ELE E++K+L L+E + ELQ +L+ S + +K
Sbjct: 132 ERLSQELEYLTEDVKRLNEKLKE--SNTTKGELQLKLDELQASDVSVK 177
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 57.2 bits (132), Expect = 2e-07
Identities = 121/584 (20%), Positives = 223/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1986 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 2045
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 2046 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 2103
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 2104 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2159
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
S E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2160 SLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGE 2219
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2398
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2399 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2457
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2458 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2513
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2514 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2556
Score = 56.0 bits (129), Expect = 4e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAE 2166
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE-MKKDMD 217
+ A + K L+A +EK H K++ L+ + + + + ++ + +
Sbjct: 2167 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDRLRGEAE 2221
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2222 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2280
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2281 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2340
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2341 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2400
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2401 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2460
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2461 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2520
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2521 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2577 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2632
Query: 610 IKLK 613
+ K
Sbjct: 2633 LSEK 2636
Score = 45.6 bits (103), Expect = 5e-04
Identities = 94/443 (21%), Positives = 178/443 (40%), Gaps = 28/443 (6%)
Query: 177 KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKE 236
+A +K+K + ++ A + K E V ++ ++E +++++ Q EG + ++E
Sbjct: 1796 QAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTAQQRLAAEQE 1851
Query: 237 LVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQTQSKTAQKRL 292
L++ + EQ Q + LE++ Q+ T K +ELE E + + + A K
Sbjct: 1852 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EMEVLLASKA- 1909
Query: 293 CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS 352
AE E T ++ +R +A + L EE EA + QL +A + +
Sbjct: 1910 --KAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAE 1967
Query: 353 VESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY 412
E L + AA AL+ L E+ A K
Sbjct: 1968 AERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 2026
Query: 413 ERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEG 472
+ ++ L +RK +S + R QK L+ D+ RQ+ E+ L + E+
Sbjct: 2027 DIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEILALKASFEKA 2074
Query: 473 AGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
A A L + ++ + + R A A + L + E R RE E ++ +
Sbjct: 2075 AAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREAEERVQKSLA 2132
Query: 532 KLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA 591
A+LE + + + A+++ +++L+ AQE +K A + A
Sbjct: 2133 AEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2192
Query: 592 QADPEELQQMRQQLENSRIKLKR 614
A ++ Q+++Q L+ + L R
Sbjct: 2193 FAVQQKEQELQQTLQQEQSVLDR 2215
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2231 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2289
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2290 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2349 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2408
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2409 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2467
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2468 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2526
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2527 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2579
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2580 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2639
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2640 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2699
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2700 EEG-VRRKQEELQQLEQQ 2716
Score = 37.5 bits (83), Expect = 0.14
Identities = 87/428 (20%), Positives = 173/428 (40%), Gaps = 43/428 (10%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++ LE ++ ++ +E+LQ AQ+E E KQ AE+ + + + E
Sbjct: 1765 ERQLERWQLKANEALRLRLQAEEVLQQKSLAQAEAE-------KQKEEAEREARRRGKAE 1817
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+Q +++ +ELE +R Q TAQ+RL E+E+ RLRA
Sbjct: 1818 EQAVRQRELAE--QELEKQR------QLAEGTAQQRLA----AEQELIRLRAETEQGEQ- 1864
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGAL 375
+ LLEE++ +L A + EL + +L+ V +++E + A++A E + +
Sbjct: 1865 --QRQLLEEELARLQREAAAATQKRQEL---EAELAKVRAEMEV-LLASKAKAEEESRST 1918
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQES 433
+ + L L EE + E D A + + + +
Sbjct: 1919 SEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAA 1978
Query: 434 L--IHRLQKRLLLVTRERDSYRQQLD--CYEKELTVTLCGEEGAGSVALLSARVQQLEKS 489
+ RL+ + +E+++ ++L ++ E+ A A + R+ QL K+
Sbjct: 1979 IGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKA 2038
Query: 490 LQG--YRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT----KLRTQRDLLTAS 543
R D + +E + E+A + ++ ++R+ + S
Sbjct: 2039 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 2098
Query: 544 LER----IGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALRE-GGAQADPEEL 598
E+ Q ++ EA++++ K L A +E ++ K AL E +A EE
Sbjct: 2099 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEA 2158
Query: 599 QQMRQQLE 606
+ +R++ E
Sbjct: 2159 RSLRERAE 2166
Score = 34.7 bits (76), Expect = 0.98
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1379 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1437
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1438 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1493
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1494 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRI 1534
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1593
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1594 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1653
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1654 LASRVKAEAEAAREKQRALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAEA 1713
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1714 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1748
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 56.8 bits (131), Expect = 2e-07
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 9/179 (5%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
DKEK L K+I LK + + +++ E++K+ + LLQ+ E +E E ++ V +
Sbjct: 1582 DKEK--LVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQH--VVE 1637
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
R E+ +L +L ++ +L+E E E + K + K A+ + + ELE+
Sbjct: 1638 AVRQEK-QELYGKLRSTEANKKETEKQLQEAEQEMEEMK--EKMRKFAKSKQQKILELEE 1694
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E RLRA D K +E + S E L+ V++E K S+ S+ +S
Sbjct: 1695 ENDRLRAEVHPAGDTA--KECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDS 1751
Score = 52.8 bits (121), Expect = 3e-06
Identities = 110/550 (20%), Positives = 221/550 (40%), Gaps = 47/550 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLI--EQHKRDERAVSDMEDXXXXXXXXXXXX 162
Q+ E R H I++ +L +EE+ +++ E++K+ + + +
Sbjct: 2396 QVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ 2455
Query: 163 KDEFNTAAKEHKDLKANWDK------EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDM 216
K + ++ K L+ + D+ + + H I KD+L++ + +++ K+++
Sbjct: 2456 KAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKL---KEEI 2512
Query: 217 DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
L ++ SE L EL++ Q +K+ +KQ E Q + KELE +
Sbjct: 2513 RGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ--LQQNKELENKYA 2570
Query: 277 SYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR-VE 334
++ +S+ A + L + L++E L SL+ +I L QV L
Sbjct: 2571 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ---LTRQVTALQEEGTL 2627
Query: 335 ALQPVQLELHEAKV-KLSSVES-------QLESWMSAARAHGVESAGALRDALESALGXX 386
L QL++ E +V +LS++ S +LE + + + G + D L+ L
Sbjct: 2628 GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHL 2687
Query: 387 XXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
E VA L + + KL +T K + I + + +
Sbjct: 2688 HHDAGIMRNETETA---EERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ 2744
Query: 447 RERDSYRQQLDCYEKELTVTL-----CGEEG---AGSVALLSARVQQLEKSLQGYRDLIA 498
RD ++LD +++ +L E+G ALLS + + + +
Sbjct: 2745 NSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLE 2804
Query: 499 AHDPHAHSK--ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI-----GPQT 551
+ SK L L +++ + + + + L+ +RD L LE+ G Q
Sbjct: 2805 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQR 2864
Query: 552 KVLHLTNNPA-AEAQKQISKELEAAQEEIKKLKVALREGGAQADPE--ELQQMRQQLENS 608
+ +PA ++ K+ L+ ++ + K L++ Q + E EL ++ QL+
Sbjct: 2865 SAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEY 2924
Query: 609 RIKLKRYSIV 618
+ K K + I+
Sbjct: 2925 QDKTKAFQIM 2934
Score = 45.2 bits (102), Expect = 7e-04
Identities = 89/546 (16%), Positives = 214/546 (39%), Gaps = 44/546 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-MQILFEEEKASLIEQHKRDERAVSDME 149
E R+ D + K ++ + V Q + E ++ E+ + +++ K + + +
Sbjct: 2090 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR 2149
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ N KE + L+ N D T Q+A + I
Sbjct: 2150 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVT----QLAAFTKSMSSLQDDRDRVI 2205
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
E KK + A++ + E+ + + + C+ LK+QL + + +++ +
Sbjct: 2206 DEAKKWERKFSDAIQSKEEEIRL----------KEDNCSVLKDQLRQMSIHMEELKINIS 2255
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELE-KEVTRLRANERSLRDAICNKLL-LEEQVH 327
LE+++ ++ Q+++C+ + E KE+ R L + N+L LE ++
Sbjct: 2256 RLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2315
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR------AHGVESAGALRDALES 381
L ++ L + E K L + Q E+ + ++ ++++ L L
Sbjct: 2316 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2375
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI------ 435
+ + +A L+ + DK +L +L + ++ +E+++
Sbjct: 2376 EINMKEQKIISLLSGKEEAIQVA--IAELRQQHDKEIKELENLLS-QEEEENIVLEEENK 2432
Query: 436 ------HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKS 489
++L + L + +E + QLD + K ++ + + ++++ S
Sbjct: 2433 KAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSL---QNDRDRIVGDYQQLEERHLS 2489
Query: 490 LQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIG 548
+ +D + ++K E +R + + +E A+ D ++ + DL +
Sbjct: 2490 IILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDS 2549
Query: 549 PQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
Q ++L + E + + +K LE +E ++ LR A EE Q + +++E+
Sbjct: 2550 QQKQLLEVQLQQNKELENKYAK-LEEKLKESEEANEDLRR-SFNALQEEKQDLSKEIESL 2607
Query: 609 RIKLKR 614
++ + +
Sbjct: 2608 KVSISQ 2613
Score = 44.4 bits (100), Expect = 0.001
Identities = 45/198 (22%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 170 AKEHKDLKANWDKEKTDLH-KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+++H + + + K K D K++A LK E + N+++ + + + + E + S
Sbjct: 2746 SRDHANEELDELKRKYDASLKELAQLK----EQGLLNRERDALLSETAFSMNSTEENSLS 2801
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD----SYKDWQTQ 284
+E L ++L+ S+ EQ L +QLE + Q + + L+ ERD + ++
Sbjct: 2802 HLEKLNQQLL---SKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKS 2858
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSL---RDAICNKLL-LEEQVHQLTSRVEALQPVQ 340
+ Q+ + EV L+ SL RD + +L L++Q Q+ + L P++
Sbjct: 2859 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLK 2918
Query: 341 LELHEAKVKLSSVESQLE 358
+L E + K + + E
Sbjct: 2919 AQLQEYQDKTKAFQIMQE 2936
Score = 42.3 bits (95), Expect = 0.005
Identities = 97/533 (18%), Positives = 214/533 (40%), Gaps = 30/533 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E +R++ + A + + +L ++ +KE + +E + + E ++ + +
Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ 1687
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKD-----LKANWD-KEKTDLHKQIADLKDKLLEANVS 204
+ E + A K+ L +N KE+ + K + K ++ +S
Sbjct: 1688 KILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMS 1747
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ-LKNQLEKQNFEFQQ 263
KD +SE +D+ ++ Q+ +E +K QT+ E+ TQ + + E+Q+
Sbjct: 1748 EKDSLSEEVQDLKHQIEDNVSKQANLEATEKH-DNQTNVTEEGTQSIPGETEEQDSLSMS 1806
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCN-MAELEKEVTRLRANERSLRDAICNKLLL 322
E S ++ ++ + N + ++++ R+ E + L
Sbjct: 1807 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTL 1866
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
E + + L S++ L E K++ + Q++ +S E+A +D LE
Sbjct: 1867 ENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV-TKLKETAEEEKDDLEER 1925
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRL 442
L + ++V + + + ++ +L E +L K
Sbjct: 1926 L------MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEK 1979
Query: 443 LLVTRE-RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHD 501
V E R Y +++ +KE +E + V+QL+K Y++ I+A +
Sbjct: 1980 TKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2039
Query: 502 PHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
KALE ++ E +++ E + ++ + R A L KV L ++
Sbjct: 2040 RTV--KALEFVQTES---QKDLEITKENLAQAVEHRKKAQAELASF----KV--LLDDTQ 2088
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+EA + ++ L+ ++E++ K +++ Q D E+L++ +Q E +K K+
Sbjct: 2089 SEAARVLADNLK-LKKELQSNKESVKSQMKQKD-EDLERRLEQAEEKHLKEKK 2139
Score = 41.1 bits (92), Expect = 0.011
Identities = 88/431 (20%), Positives = 175/431 (40%), Gaps = 40/431 (9%)
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVT 265
DQ+ E ++E Q + +E K L+ Q S + + L+ ++ K N QQ+
Sbjct: 1843 DQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQ 1902
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCN-MAELEKEVTRLRANERSLRDAICNKLLLEE 324
+L + +++ ++ + ++RL N +AEL + + + DA LLE
Sbjct: 1903 EELSRVTKLKETAEE---EKDDLEERLMNQLAELNGSIGNYC---QDVTDAQIKNELLES 1956
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSV--ESQLESWMSAARAHGVES-AGALRDALES 381
++ L V L+ + +L + K K+ S + LE A + G +S A L++ L+
Sbjct: 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKE 2016
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKR 441
L V L++ + T DL ++N + +K
Sbjct: 2017 KQQEVKQLQKDCIRYQEKISALERTVKALEFVQ---TESQKDLEITKENLAQAVEHRKK- 2072
Query: 442 LLLVTRERDSYRQQLDCYEKELTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDL 496
E S++ LD + E L +E + + ++++Q ++ L+ R L
Sbjct: 2073 ---AQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLE--RRL 2127
Query: 497 IAAHDPHAHSKA-----LESLRNEVTRWREEAEGARRDVTK----LRTQRDLLTASLERI 547
A + H K L++LR E E + + K ++ ++ L +++ ++
Sbjct: 2128 EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQL 2187
Query: 548 GPQTKVLHLTNNPAA----EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQ 603
TK + + EA+K K +A Q K+ ++ L+E ++L+QM
Sbjct: 2188 AAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQS--KEEEIRLKEDNCSVLKDQLRQMSI 2245
Query: 604 QLENSRIKLKR 614
+E +I + R
Sbjct: 2246 HMEELKINISR 2256
Score = 39.5 bits (88), Expect = 0.035
Identities = 86/497 (17%), Positives = 185/497 (37%), Gaps = 28/497 (5%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
K+L+++L K + ++ + I++++Q K +L +++K + +S
Sbjct: 1455 KQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL-KENKSLQEELSLARGTI 1513
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEM 212
+ + + KE + + + K I ++ LLE N S +
Sbjct: 1514 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE-NQS-------L 1565
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
+ L ALEG + E L KE+ ++S+ + T+ + + ++ E++ + + +
Sbjct: 1566 SSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1625
Query: 272 EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
E + + + ++ L +L + E+ L++A + +EE ++
Sbjct: 1626 SNEAERIQHVVEAVRQEKQEL--YGKLRSTEANKKETEKQLQEA---EQEMEEMKEKMRK 1680
Query: 332 RVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
++ Q LEL E +L + + S ++++ LE
Sbjct: 1681 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSK 1740
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK--NQESLIHRLQKRLLLVTRER 449
L+EEV LK++ + K +L K NQ ++ + + T E+
Sbjct: 1741 KFQSLMSEKDSLSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQ 1800
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKAL 509
DS T C E S + V + S + + D + +
Sbjct: 1801 DSLSMS--------TRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQID--QLKERI 1849
Query: 510 ESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQIS 569
L E + +E ++ + L +Q L+ + + ++L N E +++
Sbjct: 1850 AGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVT 1909
Query: 570 KELEAAQEEIKKLKVAL 586
K E A+EE L+ L
Sbjct: 1910 KLKETAEEEKDDLEERL 1926
Score = 38.7 bits (86), Expect = 0.060
Identities = 70/368 (19%), Positives = 167/368 (45%), Gaps = 29/368 (7%)
Query: 171 KEHKDLKANWDKEKTDLHKQIA--DLKDKLLEANVSNKDQISE-MKKDMDELLQALEGAQ 227
+++K+ + EK L QI+ D + K+L+ V+ + +++ +++++ + + E A+
Sbjct: 1857 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1916
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKT 287
E + L++ L+ Q AE + N Q+ Q+ ++L LE E + K ++ +
Sbjct: 1917 EEKDDLEERLMNQL--AELNGSIGNYC--QDVTDAQIKNEL--LESEMKNLKKCVSELEE 1970
Query: 288 AQKRLCN-MAELEKEVTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++L ++E E+ + + + + NK +E L + + ++ +Q +
Sbjct: 1971 EKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR 2030
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTE 405
+ K+S++E +++ + + + ++ L A+
Sbjct: 2031 YQEKISALERTVKA-LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQS 2089
Query: 406 EVA-----TLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
E A LK +++ + K + + +++ E L RL++ +E+ + +++LD
Sbjct: 2090 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR 2149
Query: 461 KELTVTLCGEEGAGSVALL----SARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
+E V L EE G + + VQQL+++L +A A +K++ SL+++
Sbjct: 2150 RE-KVHL--EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLA-----AFTKSMSSLQDDR 2201
Query: 517 TRWREEAE 524
R +EA+
Sbjct: 2202 DRVIDEAK 2209
Score = 37.5 bits (83), Expect = 0.14
Identities = 83/456 (18%), Positives = 177/456 (38%), Gaps = 42/456 (9%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+++ N E + LK + ++H + K + + ++ + + E++ +DEL +
Sbjct: 1343 QEQINKQGLEIESLKTV--SHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKL 1400
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
+ + +V L +L + + T+++ ++ +Q + + ++L+ E D
Sbjct: 1401 ISKKEEDVSYLSGQL---SEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE----- 1452
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ K Q LC M + +E+ E + I KL L SR EAL+ E
Sbjct: 1453 -RIKQLQVELCEMKQKPEEI----GEESRAKQQIQRKLQA-----ALISRKEALK----E 1498
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
+ +LS +E ++ + A A ++ LG
Sbjct: 1499 NKSLQEELSLARGTIER-LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDR 1557
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
E +L + L LT +++E L+ ++ E ++++ +KE
Sbjct: 1558 SLLENQSLSSSCESLKLALEGLT---EDKEKLVKEIESLKSSKIAESTEWQEKHKELQKE 1614
Query: 463 LTVTLCGEEG----AGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ L E A + + V+Q ++ L G A+ K L+ E+
Sbjct: 1615 YEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKET-EKQLQEAEQEMEE 1673
Query: 519 WREE----AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+E+ A+ ++ + +L + D L A + G K T + + +ELE
Sbjct: 1674 MKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMET---LLSSNASMKEELER 1730
Query: 575 AQEEIKKLKVALREGGAQAD--PEELQQMRQQLENS 608
+ E + L + ++ D EE+Q ++ Q+E++
Sbjct: 1731 VKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEDN 1766
Score = 35.1 bits (77), Expect = 0.75
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
DK T+ +I +K KL E ++ IS ++ + + QA + AQS EM +E V
Sbjct: 136 DKSSTEEEMEIEKIKHKLQE----KEELISTLQAQLTQA-QAEQPAQSSTEM--EEFVMM 188
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+ ++ + + L+ Q + Q +++ E+D+ ++TQ + + L +
Sbjct: 189 KQQLQEKEEFISTLQAQLSQ-TQAEQAAQQVVREKDAR--FETQVRLHEDELLQLVTQAD 245
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
T ++ R L+ LEE L R + + +Q EL A+ + + QL+
Sbjct: 246 VETEMQQKLRVLQRK------LEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQ 297
Score = 34.7 bits (76), Expect = 0.98
Identities = 49/217 (22%), Positives = 93/217 (42%), Gaps = 24/217 (11%)
Query: 167 NTAAKEHKDLKANWDKEKTDL------HK-QIADLKDKLLEANVSNKDQISEMKKDMDEL 219
N A E K K + DK + + H+ ++ LK ++LE ++ +K++DE
Sbjct: 655 NDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 714
Query: 220 LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT---SKLKELEY--- 273
+ + +E KK +S ++ ++QL Q E VT +++K+LE
Sbjct: 715 AKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLA 774
Query: 274 --ERDSYKDWQTQSK-----TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
ER D+++Q+ T Q ++ K+V ++ + L D +L EQ
Sbjct: 775 EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDV-KIEVLQNELDDV---QLQFSEQS 830
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
+ S LQ + E+ E ++ + S++E A
Sbjct: 831 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 867
Score = 31.5 bits (68), Expect = 9.2
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E D++ + ++ T + + L++K E + +++ + ++EL QAL + E+
Sbjct: 818 ELDDVQLQFSEQSTLIRSLQSQLQNKESEV-LEGAERVRHISSKVEELSQALSQKELEIT 876
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQSKTAQK 290
+ + L+++ E Q + ++Q E +T K+ +L E+ S + KT ++
Sbjct: 877 KMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL---GVEIKTLKE 933
Query: 291 RLCNMAELEKEVTRLRANE 309
+L N+ +E + + E
Sbjct: 934 QL-NLLSRAEEAKKEQVEE 951
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 56.8 bits (131), Expect = 2e-07
Identities = 124/544 (22%), Positives = 220/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER +++E+
Sbjct: 1997 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAE 2056
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2057 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2111
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2112 AARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2170
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2171 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2230
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2231 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2290
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2291 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2350
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2351 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2410
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2411 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2467 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2522
Query: 610 IKLK 613
+ K
Sbjct: 2523 LSEK 2526
Score = 54.8 bits (126), Expect = 9e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1876 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1935
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1936 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1993
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1994 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKANVEEAR 2049
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2050 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2109
Query: 286 KTAQKRLCNMAELEKEVTRLRANE--RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2288
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2289 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2347
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2348 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2403
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2446
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1364 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1423
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1424 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1479
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1480 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1525
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1526 LRRQVQDESQRKRQAEVELASRVKAETEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1582
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1583 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1636
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1637 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1693
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1750
Score = 45.2 bits (102), Expect = 7e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1618 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1676
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1677 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1732
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1791
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1792 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1848
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1849 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1907
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1908 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1955
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1956 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 2013
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2100
Score = 44.4 bits (100), Expect = 0.001
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2121 EEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2179
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2180 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2298
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2299 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2357
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2358 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2416
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2417 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2469
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2470 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2529
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2590 EEG-VRRKQEELQQLEQQ 2606
Score = 35.1 bits (77), Expect = 0.75
Identities = 85/399 (21%), Positives = 149/399 (37%), Gaps = 24/399 (6%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1269 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1327
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1328 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1383
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1384 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVD 1437
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
L+ R + ++ + E R+++ + +V + ++ +Q
Sbjct: 1438 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG 1497
Query: 459 YEKEL-TVTLCGEEGAGSVALLSARVQQLEKSLQ--GYRDLIAAHDPHAHSKALESLRNE 515
E EL + EE ++L + +Q R A + + KA E
Sbjct: 1498 AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAARE 1557
Query: 516 VTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAA 575
R + E R + +R L A +ER Q +V T +AEA+ Q SK A
Sbjct: 1558 KQRALQALEELRLQAEE--AERRLRQAEVER-ARQVQVALETAQRSAEAELQ-SKRASFA 1613
Query: 576 QEEIKKLKVALRE---GGAQADPEELQQMRQQLENSRIK 611
E+ +L+ +L+E AQ E ++ +QQ E R +
Sbjct: 1614 -EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1651
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 56.8 bits (131), Expect = 2e-07
Identities = 124/544 (22%), Positives = 220/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER +++E+
Sbjct: 1997 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAE 2056
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2057 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2111
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2112 AARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2170
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2171 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2230
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2231 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2290
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2291 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2350
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2351 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2410
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2411 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2467 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2522
Query: 610 IKLK 613
+ K
Sbjct: 2523 LSEK 2526
Score = 54.8 bits (126), Expect = 9e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1876 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1935
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1936 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1993
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1994 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKANVEEAR 2049
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2050 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2109
Query: 286 KTAQKRLCNMAELEKEVTRLRANE--RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2288
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2289 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2347
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2348 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2403
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2446
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1364 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1423
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1424 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1479
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1480 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1525
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1526 LRRQVQDESQRKRQAEVELASRVKAETEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1582
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1583 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1636
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1637 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1693
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1750
Score = 45.2 bits (102), Expect = 7e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1618 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1676
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1677 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1732
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1791
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1792 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1848
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1849 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1907
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1908 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1955
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1956 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 2013
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2100
Score = 44.4 bits (100), Expect = 0.001
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2121 EEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2179
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2180 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2298
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2299 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2357
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2358 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2416
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2417 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2469
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2470 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2529
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2590 EEG-VRRKQEELQQLEQQ 2606
Score = 35.1 bits (77), Expect = 0.75
Identities = 85/399 (21%), Positives = 149/399 (37%), Gaps = 24/399 (6%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1269 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1327
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1328 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1383
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1384 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVD 1437
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
L+ R + ++ + E R+++ + +V + ++ +Q
Sbjct: 1438 AQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGG 1497
Query: 459 YEKEL-TVTLCGEEGAGSVALLSARVQQLEKSLQ--GYRDLIAAHDPHAHSKALESLRNE 515
E EL + EE ++L + +Q R A + + KA E
Sbjct: 1498 AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAARE 1557
Query: 516 VTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAA 575
R + E R + +R L A +ER Q +V T +AEA+ Q SK A
Sbjct: 1558 KQRALQALEELRLQAEE--AERRLRQAEVER-ARQVQVALETAQRSAEAELQ-SKRASFA 1613
Query: 576 QEEIKKLKVALRE---GGAQADPEELQQMRQQLENSRIK 611
E+ +L+ +L+E AQ E ++ +QQ E R +
Sbjct: 1614 -EKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1651
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 49/179 (27%), Positives = 85/179 (47%), Gaps = 9/179 (5%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
DKEK L K+I LK + + +++ E++K+ + LLQ+ E +E E ++ V +
Sbjct: 1548 DKEK--LVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQH--VVE 1603
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
R E+ +L +L ++ +L+E E E + K + K A+ + + ELE+
Sbjct: 1604 AVRQEK-QELYGKLRSTEANKKETEKQLQEAEQEMEEMK--EKMRKFAKSKQQKILELEE 1660
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
E RLRA D K +E + S E L+ V++E K S+ S+ +S
Sbjct: 1661 ENDRLRAEVHPAGDTA--KECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDS 1717
Score = 52.8 bits (121), Expect = 3e-06
Identities = 110/550 (20%), Positives = 221/550 (40%), Gaps = 47/550 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLI--EQHKRDERAVSDMEDXXXXXXXXXXXX 162
Q+ E R H I++ +L +EE+ +++ E++K+ + + +
Sbjct: 2362 QVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ 2421
Query: 163 KDEFNTAAKEHKDLKANWDK------EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDM 216
K + ++ K L+ + D+ + + H I KD+L++ + +++ K+++
Sbjct: 2422 KAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKL---KEEI 2478
Query: 217 DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
L ++ SE L EL++ Q +K+ +KQ E Q + KELE +
Sbjct: 2479 RGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ--LQQNKELENKYA 2536
Query: 277 SYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR-VE 334
++ +S+ A + L + L++E L SL+ +I L QV L
Sbjct: 2537 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ---LTRQVTALQEEGTL 2593
Query: 335 ALQPVQLELHEAKV-KLSSVES-------QLESWMSAARAHGVESAGALRDALESALGXX 386
L QL++ E +V +LS++ S +LE + + + G + D L+ L
Sbjct: 2594 GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHL 2653
Query: 387 XXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
E VA L + + KL +T K + I + + +
Sbjct: 2654 HHDAGIMRNETETA---EERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ 2710
Query: 447 RERDSYRQQLDCYEKELTVTL-----CGEEG---AGSVALLSARVQQLEKSLQGYRDLIA 498
RD ++LD +++ +L E+G ALLS + + + +
Sbjct: 2711 NSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLE 2770
Query: 499 AHDPHAHSK--ALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI-----GPQT 551
+ SK L L +++ + + + + L+ +RD L LE+ G Q
Sbjct: 2771 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQR 2830
Query: 552 KVLHLTNNPA-AEAQKQISKELEAAQEEIKKLKVALREGGAQADPE--ELQQMRQQLENS 608
+ +PA ++ K+ L+ ++ + K L++ Q + E EL ++ QL+
Sbjct: 2831 SAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEY 2890
Query: 609 RIKLKRYSIV 618
+ K K + I+
Sbjct: 2891 QDKTKAFQIM 2900
Score = 45.2 bits (102), Expect = 7e-04
Identities = 89/546 (16%), Positives = 214/546 (39%), Gaps = 44/546 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-MQILFEEEKASLIEQHKRDERAVSDME 149
E R+ D + K ++ + V Q + E ++ E+ + +++ K + + +
Sbjct: 2056 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR 2115
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ N KE + L+ N D T Q+A + I
Sbjct: 2116 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVT----QLAAFTKSMSSLQDDRDRVI 2171
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
E KK + A++ + E+ + + + C+ LK+QL + + +++ +
Sbjct: 2172 DEAKKWERKFSDAIQSKEEEIRL----------KEDNCSVLKDQLRQMSIHMEELKINIS 2221
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELE-KEVTRLRANERSLRDAICNKLL-LEEQVH 327
LE+++ ++ Q+++C+ + E KE+ R L + N+L LE ++
Sbjct: 2222 RLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2281
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR------AHGVESAGALRDALES 381
L ++ L + E K L + Q E+ + ++ ++++ L L
Sbjct: 2282 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2341
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI------ 435
+ + +A L+ + DK +L +L + ++ +E+++
Sbjct: 2342 EINMKEQKIISLLSGKEEAIQVA--IAELRQQHDKEIKELENLLS-QEEEENIVLEEENK 2398
Query: 436 ------HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKS 489
++L + L + +E + QLD + K ++ + + ++++ S
Sbjct: 2399 KAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSL---QNDRDRIVGDYQQLEERHLS 2455
Query: 490 LQGYRDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIG 548
+ +D + ++K E +R + + +E A+ D ++ + DL +
Sbjct: 2456 IILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDS 2515
Query: 549 PQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
Q ++L + E + + +K LE +E ++ LR A EE Q + +++E+
Sbjct: 2516 QQKQLLEVQLQQNKELENKYAK-LEEKLKESEEANEDLRR-SFNALQEEKQDLSKEIESL 2573
Query: 609 RIKLKR 614
++ + +
Sbjct: 2574 KVSISQ 2579
Score = 44.4 bits (100), Expect = 0.001
Identities = 45/198 (22%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 170 AKEHKDLKANWDKEKTDLH-KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+++H + + + K K D K++A LK E + N+++ + + + + E + S
Sbjct: 2712 SRDHANEELDELKRKYDASLKELAQLK----EQGLLNRERDALLSETAFSMNSTEENSLS 2767
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD----SYKDWQTQ 284
+E L ++L+ S+ EQ L +QLE + Q + + L+ ERD + ++
Sbjct: 2768 HLEKLNQQLL---SKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKS 2824
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSL---RDAICNKLL-LEEQVHQLTSRVEALQPVQ 340
+ Q+ + EV L+ SL RD + +L L++Q Q+ + L P++
Sbjct: 2825 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLK 2884
Query: 341 LELHEAKVKLSSVESQLE 358
+L E + K + + E
Sbjct: 2885 AQLQEYQDKTKAFQIMQE 2902
Score = 43.2 bits (97), Expect = 0.003
Identities = 97/533 (18%), Positives = 214/533 (40%), Gaps = 30/533 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E +R++ + A + + +L ++ +KE + +E + + E ++ + +
Sbjct: 1594 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ 1653
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKD-----LKANWD-KEKTDLHKQIADLKDKLLEANVS 204
+ E + A K+ L +N KE+ + K + K ++ +S
Sbjct: 1654 KILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMS 1713
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ-LKNQLEKQNFEFQQ 263
KD +SE +D+ ++ Q+ +E +K QT+ E+ TQ + + E+Q+
Sbjct: 1714 EKDSLSEEVQDLKHQIEGNVSKQANLEATEKH-DNQTNVTEEGTQSIPGETEEQDSLSMS 1772
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCN-MAELEKEVTRLRANERSLRDAICNKLLL 322
E S ++ ++ + N + ++++ R+ E + L
Sbjct: 1773 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTL 1832
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
E + + L S++ L E K++ + Q++ +S E+A +D LE
Sbjct: 1833 ENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV-TKLKETAEEEKDDLEER 1891
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRL 442
L + ++V + + + ++ +L E +L K
Sbjct: 1892 L------MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEK 1945
Query: 443 LLVTRE-RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHD 501
V E R Y +++ +KE +E + V+QL+K Y++ I+A +
Sbjct: 1946 TKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2005
Query: 502 PHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
KALE ++ E +++ E + ++ + R A L KV L ++
Sbjct: 2006 RTV--KALEFVQTES---QKDLEITKENLAQAVEHRKKAQAELASF----KV--LLDDTQ 2054
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+EA + ++ L+ ++E++ K +++ Q D E+L++ +Q E +K K+
Sbjct: 2055 SEAARVLADNLK-LKKELQSNKESVKSQMKQKD-EDLERRLEQAEEKHLKEKK 2105
Score = 41.5 bits (93), Expect = 0.009
Identities = 44/180 (24%), Positives = 82/180 (45%), Gaps = 15/180 (8%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
DK T+ +I +K KL E ++ IS ++ + + QA + AQS EM + ++KQ
Sbjct: 97 DKSSTEEEMEIEKIKHKLQE----KEELISTLQAQLTQA-QAEQPAQSSTEMEEFVMMKQ 151
Query: 241 T--SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
+ E + L+ QL + E S ++++ E+D+ ++TQ + + L +
Sbjct: 152 QLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDAR--FETQVRLHEDELLQLVTQ 209
Query: 299 EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
T ++ R L+ LEE L R + + +Q EL A+ + + QL+
Sbjct: 210 ADVETEMQQKLRVLQRK------LEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQ 263
Score = 41.1 bits (92), Expect = 0.011
Identities = 88/431 (20%), Positives = 175/431 (40%), Gaps = 40/431 (9%)
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVT 265
DQ+ E ++E Q + +E K L+ Q S + + L+ ++ K N QQ+
Sbjct: 1809 DQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQ 1868
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCN-MAELEKEVTRLRANERSLRDAICNKLLLEE 324
+L + +++ ++ + ++RL N +AEL + + + DA LLE
Sbjct: 1869 EELSRVTKLKETAEE---EKDDLEERLMNQLAELNGSIGNYC---QDVTDAQIKNELLES 1922
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSV--ESQLESWMSAARAHGVES-AGALRDALES 381
++ L V L+ + +L + K K+ S + LE A + G +S A L++ L+
Sbjct: 1923 EMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKE 1982
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKR 441
L V L++ + T DL ++N + +K
Sbjct: 1983 KQQEVKQLQKDCIRYQEKISALERTVKALEFVQ---TESQKDLEITKENLAQAVEHRKK- 2038
Query: 442 LLLVTRERDSYRQQLDCYEKELTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDL 496
E S++ LD + E L +E + + ++++Q ++ L+ R L
Sbjct: 2039 ---AQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLE--RRL 2093
Query: 497 IAAHDPHAHSKA-----LESLRNEVTRWREEAEGARRDVTK----LRTQRDLLTASLERI 547
A + H K L++LR E E + + K ++ ++ L +++ ++
Sbjct: 2094 EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQL 2153
Query: 548 GPQTKVLHLTNNPAA----EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQ 603
TK + + EA+K K +A Q K+ ++ L+E ++L+QM
Sbjct: 2154 AAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQS--KEEEIRLKEDNCSVLKDQLRQMSI 2211
Query: 604 QLENSRIKLKR 614
+E +I + R
Sbjct: 2212 HMEELKINISR 2222
Score = 39.1 bits (87), Expect = 0.046
Identities = 86/497 (17%), Positives = 185/497 (37%), Gaps = 28/497 (5%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
K+L+++L K + ++ + I++++Q K +L +++K + +S
Sbjct: 1421 KQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL-KENKSLQEELSLARGTI 1479
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEM 212
+ + + KE + + + K I ++ LLE N S +
Sbjct: 1480 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE-NQS-------L 1531
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
+ L ALEG + E L KE+ ++S+ + T+ + + ++ E++ + + +
Sbjct: 1532 SSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1591
Query: 272 EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
E + + + ++ L +L + E+ L++A + +EE ++
Sbjct: 1592 SNEAERIQHVVEAVRQEKQEL--YGKLRSTEANKKETEKQLQEA---EQEMEEMKEKMRK 1646
Query: 332 RVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
++ Q LEL E +L + + S ++++ LE
Sbjct: 1647 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSK 1706
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK--NQESLIHRLQKRLLLVTRER 449
L+EEV LK++ + K +L K NQ ++ + + T E+
Sbjct: 1707 KFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQ 1766
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKAL 509
DS T C E S + V + S + + D + +
Sbjct: 1767 DSLSMS--------TRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQID--QLKERI 1815
Query: 510 ESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQIS 569
L E + +E ++ + L +Q L+ + + ++L N E +++
Sbjct: 1816 AGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVT 1875
Query: 570 KELEAAQEEIKKLKVAL 586
K E A+EE L+ L
Sbjct: 1876 KLKETAEEEKDDLEERL 1892
Score = 38.7 bits (86), Expect = 0.060
Identities = 70/368 (19%), Positives = 167/368 (45%), Gaps = 29/368 (7%)
Query: 171 KEHKDLKANWDKEKTDLHKQIA--DLKDKLLEANVSNKDQISE-MKKDMDELLQALEGAQ 227
+++K+ + EK L QI+ D + K+L+ V+ + +++ +++++ + + E A+
Sbjct: 1823 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1882
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKT 287
E + L++ L+ Q AE + N Q+ Q+ ++L LE E + K ++ +
Sbjct: 1883 EEKDDLEERLMNQL--AELNGSIGNYC--QDVTDAQIKNEL--LESEMKNLKKCVSELEE 1936
Query: 288 AQKRLCN-MAELEKEVTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+++L ++E E+ + + + + NK +E L + + ++ +Q +
Sbjct: 1937 EKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR 1996
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTE 405
+ K+S++E +++ + + + ++ L A+
Sbjct: 1997 YQEKISALERTVKA-LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQS 2055
Query: 406 EVA-----TLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE 460
E A LK +++ + K + + +++ E L RL++ +E+ + +++LD
Sbjct: 2056 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR 2115
Query: 461 KELTVTLCGEEGAGSVALL----SARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
+E V L EE G + + VQQL+++L +A A +K++ SL+++
Sbjct: 2116 RE-KVHL--EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLA-----AFTKSMSSLQDDR 2167
Query: 517 TRWREEAE 524
R +EA+
Sbjct: 2168 DRVIDEAK 2175
Score = 37.1 bits (82), Expect = 0.18
Identities = 83/456 (18%), Positives = 176/456 (38%), Gaps = 42/456 (9%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+++ N E + LK + ++H + K + + ++ + + E++ +DEL +
Sbjct: 1309 QEQINKQGLEIESLKTV--SHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKL 1366
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
+ + +V L +L + + T+++ ++ +Q + + ++L+ E D
Sbjct: 1367 ISKKEEDVSYLSGQL---SEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE----- 1418
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ K Q LC M + +E+ E + I KL L SR EAL+ E
Sbjct: 1419 -RIKQLQVELCEMKQKPEEI----GEESRAKQQIQRKLQA-----ALISRKEALK----E 1464
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
+ +LS +E ++ + A A ++ LG
Sbjct: 1465 NKSLQEELSLARGTIER-LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDR 1523
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
E +L + L LT +++E L+ ++ E ++++ +KE
Sbjct: 1524 SLLENQSLSSSCESLKLALEGLT---EDKEKLVKEIESLKSSKIAESTEWQEKHKELQKE 1580
Query: 463 LTVTLCGEEG----AGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ L E A + + V+Q ++ L G A+ K L+ E+
Sbjct: 1581 YEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKET-EKQLQEAEQEMEE 1639
Query: 519 WREE----AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+E+ A+ ++ + +L + D L A + G K T + + +ELE
Sbjct: 1640 MKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMET---LLSSNASMKEELER 1696
Query: 575 AQEEIKKLKVALREGGAQAD--PEELQQMRQQLENS 608
+ E + L + ++ D EE+Q ++ Q+E +
Sbjct: 1697 VKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1732
Score = 34.7 bits (76), Expect = 0.98
Identities = 49/217 (22%), Positives = 93/217 (42%), Gaps = 24/217 (11%)
Query: 167 NTAAKEHKDLKANWDKEKTDL------HK-QIADLKDKLLEANVSNKDQISEMKKDMDEL 219
N A E K K + DK + + H+ ++ LK ++LE ++ +K++DE
Sbjct: 621 NDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 680
Query: 220 LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT---SKLKELEY--- 273
+ + +E KK +S ++ ++QL Q E VT +++K+LE
Sbjct: 681 AKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLA 740
Query: 274 --ERDSYKDWQTQSK-----TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
ER D+++Q+ T Q ++ K+V ++ + L D +L EQ
Sbjct: 741 EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDV-KIEVLQNELDDV---QLQFSEQS 796
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
+ S LQ + E+ E ++ + S++E A
Sbjct: 797 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 833
Score = 31.5 bits (68), Expect = 9.2
Identities = 28/139 (20%), Positives = 66/139 (47%), Gaps = 6/139 (4%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E D++ + ++ T + + L++K E + +++ + ++EL QAL + E+
Sbjct: 784 ELDDVQLQFSEQSTLIRSLQSQLQNKESEV-LEGAERVRHISSKVEELSQALSQKELEIT 842
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQSKTAQK 290
+ + L+++ E Q + ++Q E +T K+ +L E+ S + KT ++
Sbjct: 843 KMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL---GVEIKTLKE 899
Query: 291 RLCNMAELEKEVTRLRANE 309
+L N+ +E + + E
Sbjct: 900 QL-NLLSRAEEAKKEQVEE 917
Score = 31.5 bits (68), Expect = 9.2
Identities = 52/263 (19%), Positives = 111/263 (42%), Gaps = 20/263 (7%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
+ S N + +E+ L + ASL E + E+ + + E E N+
Sbjct: 2706 MSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENS 2765
Query: 169 AAKEHKDLKANWDKEKTDLH--KQIADLKDKLL---EANVSNKDQISEMKKDMDELLQAL 223
+ K + K++ LH Q+ D +++ +A S +++ + ++++ ++
Sbjct: 2766 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE 2825
Query: 224 EGAQ----------SEVEMLKKELVK-QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
EG Q +EV+ LKK + Q R +LKN L++Q + Q ++L L+
Sbjct: 2826 EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKN-LQQQYLQINQEITELHPLK 2884
Query: 273 YERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
+ Y+D + Q+ L + E+ +LR + S I + + E+ + ++
Sbjct: 2885 AQLQEYQDKTKAFQIMQEELRQENLSWQHELDQLRMEKSSWE--IHERRMKEQYLMAISD 2942
Query: 332 RVEALQPVQLELHEAKVKLSSVE 354
+ + L +Q + E + S +
Sbjct: 2943 KDQQLSHLQNLIRELRSSSSQTQ 2965
>BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631
protein.
Length = 701
Score = 56.4 bits (130), Expect = 3e-07
Identities = 71/339 (20%), Positives = 140/339 (41%), Gaps = 10/339 (2%)
Query: 41 STQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKRLRRD--SSGNGTTAPPSPWETKRLKID 98
S Q + + + +L SS+G + D R ++ G A + RL
Sbjct: 179 SLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKH 238
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
+ A +AQ+ + E + + +++ ++E+ + Q + DE+ +S+ E
Sbjct: 239 VEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTE 298
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEKTDLHK-QIADLKDKLLEANVSN-KDQISEMKKDM 216
K + T +E K + + + + Q + E V ++Q+ +++ +
Sbjct: 299 TSDLKTKMATLERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQV 358
Query: 217 DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE-KQNFEFQQVTSKLKELEYER 275
L+ LEGA +V EL K+ +R + + + L+ KQ +Q+ S +E E R
Sbjct: 359 QLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELR 418
Query: 276 DSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
S + + Q +++L +E E+ +LRA + L+ K LE+ L +
Sbjct: 419 GSLDEAEAQRARVEEQL--QSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILE 476
Query: 336 LQPVQLELHEAK---VKLSSVESQLESWMSAARAHGVES 371
L+ EL E + V + E+ + R+ VES
Sbjct: 477 LERELEELKERERLLVAFPDLHRPTETQIHGGRSSSVES 515
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2030 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2085 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2143
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2144 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2203
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2204 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2263
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2264 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2323
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2384 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2440 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2495
Query: 610 IKLK 613
+ K
Sbjct: 2496 LSEK 2499
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1908
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1909 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1966
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2022
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2023 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2082
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2261
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2262 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2320
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2321 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2376
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2377 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2419
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1396
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1397 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1452
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1453 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1498
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1555
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1556 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1609
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1610 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1666
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1723
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1591 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1649
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1705
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1764
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1765 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1821
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1822 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1880
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1881 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1928
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1929 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1986
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2094 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2152
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2153 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2271
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2330
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2389
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2390 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2442
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2563 EEG-VRRKQEELQQLEQQ 2579
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1300
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1301 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1356
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1357 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1397
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1577 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1611
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1974 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2033
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2034 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2088
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2089 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2147
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2148 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2207
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2208 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2267
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2268 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2327
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2328 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2387
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2388 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2444 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2499
Query: 610 IKLK 613
+ K
Sbjct: 2500 LSEK 2503
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1853 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1912
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1913 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1970
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1971 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2026
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2027 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2086
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2087 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2146
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2147 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2206
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2265
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2266 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2324
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2325 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2380
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2381 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2423
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1341 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1400
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1401 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1456
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1457 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1502
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1503 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1559
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1560 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1613
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1614 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1670
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1727
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1595 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1653
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1654 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1709
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1768
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1769 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1825
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1826 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1884
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1885 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1932
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1933 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1990
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1991 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2077
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2098 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2156
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2157 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2215
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2216 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2275
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2276 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2334
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2335 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2393
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2394 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2446
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2447 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2506
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2507 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2566
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2567 EEG-VRRKQEELQQLEQQ 2583
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1246 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1304
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1305 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1360
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1361 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1401
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1460
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1461 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1520
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1521 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1580
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1581 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1615
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2030 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2085 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2143
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2144 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2203
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2204 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2263
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2264 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2323
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2383
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2384 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2440 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2495
Query: 610 IKLK 613
+ K
Sbjct: 2496 LSEK 2499
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1908
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1909 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1966
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1967 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2022
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2023 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2082
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2083 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2142
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2143 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2202
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2261
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2262 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2320
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2321 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2376
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2377 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2419
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1337 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1396
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1397 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1452
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1453 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1498
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1499 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1555
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1556 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1609
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1610 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1666
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1723
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1591 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1649
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1705
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1764
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1765 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1821
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1822 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1880
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1881 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1928
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1929 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1986
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2073
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2094 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2152
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2153 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2271
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2330
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2331 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2389
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2390 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2442
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2443 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2502
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2503 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2563 EEG-VRRKQEELQQLEQQ 2579
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1300
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1301 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1356
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1357 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1397
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1456
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1457 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1516
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1517 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1576
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1577 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1611
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1938 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 1997
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 1998 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2052
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2053 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2111
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2112 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2171
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2172 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2231
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2232 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2291
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2292 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2351
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2352 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2408 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2463
Query: 610 IKLK 613
+ K
Sbjct: 2464 LSEK 2467
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1817 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1876
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1877 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1934
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1935 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 1990
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 1991 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2050
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2051 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2110
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2111 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2170
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2229
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2230 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2288
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2289 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2344
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2345 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2387
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1305 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1364
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1365 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1420
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1421 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1466
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1467 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1523
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1524 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1577
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1578 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1634
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1691
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1559 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1617
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1618 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1673
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1732
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1733 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1789
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1790 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1848
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1849 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1896
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1897 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1954
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1955 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2014
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2015 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2041
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2062 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2120
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2121 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2179
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2180 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2239
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2240 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2298
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2299 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2357
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2358 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2410
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2411 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2470
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2471 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2530
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2531 EEG-VRRKQEELQQLEQQ 2547
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1210 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1268
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1269 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1324
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1325 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1365
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1366 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1424
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1425 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1484
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1485 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1544
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1545 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1579
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2166
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2167 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2221
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2222 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2280
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2281 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2340
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2341 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2400
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2401 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2460
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2461 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2520
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2521 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2577 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2632
Query: 610 IKLK 613
+ K
Sbjct: 2633 LSEK 2636
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1986 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 2045
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 2046 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 2103
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 2104 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2159
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2160 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2219
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2279
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2280 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2339
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2398
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2399 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2457
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2458 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2513
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2514 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2556
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1474 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1533
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1534 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1589
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1590 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1635
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1636 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1692
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1693 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1746
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1747 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1803
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1860
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1728 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1786
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1787 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1842
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1901
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1902 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1958
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1959 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 2017
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 2018 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 2065
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 2066 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 2123
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 2124 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2183
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2184 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2210
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2231 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2289
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2290 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2349 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2408
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2409 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2467
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2468 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2526
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2527 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2579
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2580 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2639
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2640 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2699
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2700 EEG-VRRKQEELQQLEQQ 2716
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1379 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1437
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1438 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1493
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1494 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1534
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1593
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1594 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1653
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1654 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1713
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1714 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1748
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1948 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2007
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2008 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2062
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2063 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2121
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2122 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2181
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2182 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2241
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2242 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2301
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2302 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2361
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2362 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2418 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2473
Query: 610 IKLK 613
+ K
Sbjct: 2474 LSEK 2477
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1827 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1886
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1887 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1944
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1945 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2000
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2001 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2060
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2061 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2120
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2121 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2180
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2239
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2240 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2298
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2299 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2354
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2355 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2397
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1315 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1374
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1375 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1430
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1431 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1476
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1477 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1533
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1534 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1587
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1588 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1644
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1701
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1569 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1627
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1628 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1683
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1742
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1743 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1799
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1800 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1858
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1859 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1906
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1907 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1964
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1965 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2024
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2025 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2051
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2072 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2130
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2131 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2189
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2190 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2249
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2250 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2308
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2309 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2367
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2368 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2420
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2421 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2480
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2481 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2540
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2541 EEG-VRRKQEELQQLEQQ 2557
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1220 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1278
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1279 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1334
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1335 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1375
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1376 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1434
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1435 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1494
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1495 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1554
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1555 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1589
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1956 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2015
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2016 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2070
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2071 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2129
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2130 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2189
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2190 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2249
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2250 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2309
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2310 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2369
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2370 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2426 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2481
Query: 610 IKLK 613
+ K
Sbjct: 2482 LSEK 2485
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1835 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1894
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1895 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1952
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1953 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2008
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2009 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2068
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2069 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2128
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2129 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2188
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2247
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2248 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2306
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2307 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2362
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2363 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2405
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1323 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1382
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1383 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1438
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1439 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1484
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1485 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1541
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1542 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1595
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1596 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1652
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1709
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1577 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1635
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1636 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1691
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1750
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1751 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1807
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1808 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1866
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1867 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1914
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1915 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 1972
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 1973 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2032
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2033 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2059
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2080 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2138
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2139 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2197
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2198 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2257
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2258 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2316
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2317 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2375
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2376 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2428
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2429 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2488
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2489 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2548
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2549 EEG-VRRKQEELQQLEQQ 2565
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1228 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1286
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1287 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1342
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1343 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1383
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1384 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1442
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1443 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1502
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1503 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1562
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1563 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1597
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 56.4 bits (130), Expect = 3e-07
Identities = 124/544 (22%), Positives = 219/544 (40%), Gaps = 45/544 (8%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXX 159
A + Q+ E R + R + + EEE A + + ER + +E+
Sbjct: 1997 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2056
Query: 160 XXXKDEFNTAAKE-HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-SEMKKDMD 217
+ A + K L+A +EK H K++ L+ + + + +++ + +
Sbjct: 2057 QESARQLQLAQEAAQKRLQA---EEKA--HAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2111
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ---NFEFQQVTSKLKELEYE 274
+A E A+ ++E + + E+ +LK E+Q + Q KL++ E E
Sbjct: 2112 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRK-EAE 2170
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVT----RLRANERSLRDAICNKLLLEEQVHQLT 330
+++ + Q + +++ AE+EK LR + ++ +L LEE HQ
Sbjct: 2171 QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2230
Query: 331 SRVEALQPVQLELHEAKVKLSSVESQL--------ESWMSAARAHGVESAGALRDA--LE 380
E LQ ++ E EA + S VE +L E AR A LRD +
Sbjct: 2231 LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ 2290
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKY--ERDKATGKLNDLTTVRKNQESL--IH 436
L +E A L+ E D A + +++ +++
Sbjct: 2291 RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT 2350
Query: 437 RLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSA-RVQQLEKSLQGY 493
RL+ L+ ++++ ++Q +KE EE G L A R +QLE S +
Sbjct: 2351 RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE 2410
Query: 494 R-DLIAAHDPHAHSKALESLRNEVTRWREEAE--GARRDVTKLRTQRDL-LTASLERIGP 549
R L A A ++A E + R+R++AE G + T+L TQ + L +LE
Sbjct: 2411 RLKLRVAEMSRAQARAEE----DAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
Q+ H EA ++ +E E Q+E K L++ E E+L Q Q L+ S
Sbjct: 2467 QSD--HDAER-LREAIAELEREKEKLQQEAKLLQLKSEE-MQTVQQEQLLQETQALQQSF 2522
Query: 610 IKLK 613
+ K
Sbjct: 2523 LSEK 2526
Score = 55.6 bits (128), Expect = 5e-07
Identities = 120/584 (20%), Positives = 222/584 (38%), Gaps = 39/584 (6%)
Query: 57 KRKSSIGSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKL-ESRVNH 115
K ++ I + ++RLRR + + + K D+ AQ+ K +S +
Sbjct: 1876 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1935
Query: 116 QH-----TIRKEMQILFEEEKASLIEQHKRDERAVSDME---DXXXXXXXXXXXXKDEFN 167
Q T+R+ Q+ EEE +L ++ +++E K++
Sbjct: 1936 QKGLVEDTLRQRRQV--EEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE 1993
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A + L A ++ + + +++ K L A Q ++++ L +E A+
Sbjct: 1994 LEAARQRQLAAEEERRRREAEERV----QKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2049
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF--QQVTSKLKELEYERDSYKDWQTQS 285
E ++E +Q A++ Q + Q E++ F QQ +L++ + S D
Sbjct: 2050 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2109
Query: 286 KTAQKRLCNMAELEKEVTRLRA--NERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
A +R AE + A + R + +A K EEQ A + ++ E
Sbjct: 2110 AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEA 2169
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH- 402
+ + + E AA A + L
Sbjct: 2170 EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQK 2229
Query: 403 --LTEEVATLKYERDKATGKLN----DLTTVRKNQESLIHRLQKRL-----LLVTRERDS 451
L EE+ LK E +A + + +L +VR E L +L+ R+ L+ R++D+
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL-SKLKARIEAENRALILRDKDN 2288
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALL-SARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ L E E + E SVA +AR++QL + + +A +A++
Sbjct: 2289 TQRFLQ-EEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2347
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
E TR + EAE ++ + Q L E++ Q EA++Q
Sbjct: 2348 ----EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQL 2403
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
E+ A E +K + A+A+ E+ Q+ R+Q E KL R
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAE-EDAQRFRKQAEEIGEKLHR 2446
Score = 50.8 bits (116), Expect = 1e-05
Identities = 101/418 (24%), Positives = 170/418 (40%), Gaps = 51/418 (12%)
Query: 209 ISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
ISE + M+E + E ++E + ++ L KQ AE Q K Q E++ E QQ
Sbjct: 1364 ISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR 1423
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+ E+ ++ D Q Q ++ Q+ L + + + ++A R A ++L +EE
Sbjct: 1424 MQE--EVVRREEAAVDAQQQKRSIQEELQQLRQSSE--AEIQAKARQAEAAERSRLRIEE 1479
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
++ RV V+L+L + + E +L+ A RA E+ R A E A
Sbjct: 1480 EI-----RV-----VRLQLEATERQRGGAEGELQ----ALRARAEEAEAQKRQAQEEAER 1525
Query: 385 XXXXXXXXXXXXXXXXXHLTEEV-ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L V A + R+K L L +R E RL R
Sbjct: 1526 LRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-LQALEELRLQAEEAERRL--RQA 1582
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA----- 498
V R R + L+ ++ L + A + + QLE+SLQ +A
Sbjct: 1583 EVERARQ-VQVALETAQRSAEAELQSKR-----ASFAEKTAQLERSLQEEHVAVAQLREE 1636
Query: 499 ----AHDPHAHSKALESLRNEVTRWREEAEGA---RRDVTKLRTQRDLLTASLERIGPQT 551
A +A E E+ RW+ +A A R ++ Q+ L A E+ Q
Sbjct: 1637 AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QK 1693
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ---ADPEELQQMRQQLE 606
+ +A++Q ++ E A++E++K + L EG AQ A +EL ++R + E
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQR-QLAEGTAQQRLAAEQELIRLRAETE 1750
Score = 45.6 bits (103), Expect = 5e-04
Identities = 101/507 (19%), Positives = 197/507 (38%), Gaps = 29/507 (5%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+LE + +H +++ E E + E A ++E + +
Sbjct: 1618 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE-RWQLKANEALRLRLQAE 1676
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
A++ +A +K+K + ++ A + K E V ++ ++E +++++ Q EG
Sbjct: 1677 EVAQQKSLAQAEAEKQKEEAERE-ARRRGKAEEQAVRQRE-LAE--QELEKQRQLAEGTA 1732
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQT 283
+ ++EL++ + EQ Q + LE++ Q+ T K +ELE E + +
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA-EM 1791
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLEL 343
+ A K AE E T ++ +R +A + L EE EA + QL
Sbjct: 1792 EVLLASKA---RAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1848
Query: 344 HEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
+A + + E L + AA AL+ L
Sbjct: 1849 EDAARQRAEAERVLAEKL-AAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1907
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
E+ A K + ++ L +RK +S + R QK L+ D+ RQ+ E+ L
Sbjct: 1908 EEQAAQHKADIEER------LAQLRKASDSELER-QKGLV-----EDTLRQRRQVEEEIL 1955
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQG-YRDLIAAHDPHAHSKALESLRNEVTRWREE 522
+ E+ A A L + ++ + + R A A + L + E R RE
Sbjct: 1956 ALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAA--EEERRRREA 2013
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
E ++ + A+LE + + A+++ +++L+ AQE +K
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
A + A A ++ Q+++Q L+ +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQ 2100
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/498 (19%), Positives = 186/498 (37%), Gaps = 26/498 (5%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E ++ E E A Q + ER E+ ++ A++ +A
Sbjct: 2121 EEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAA-EKLRKEAEQEAARRAQA 2179
Query: 181 DKEKTDLHKQIADLK-DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
++ KQ AD + +K + Q +++++++ L LE + +L +EL +
Sbjct: 2180 EQAALR-QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQ---QVTSKLK---ELEYERDSYKDWQTQSKTAQKRLC 293
+ A + + ++Q+E++ F + + SKLK E E +D + Q+
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAE 2298
Query: 294 NMAELEKEVTRLR--ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
M ++ +E RL A E + + + L +++ E +Q VQ E K +
Sbjct: 2299 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ-EATRLKAEAE 2357
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++ Q E AR + + E G E +
Sbjct: 2358 LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE-AERLKLRV 2416
Query: 412 YERDKATGKLN-DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
E +A + D RK E + +L R L T+E+ + Q L+ ++ +
Sbjct: 2417 AEMSRAQARAEEDAQRFRKQAEEIGEKLH-RTELATQEKVTLVQTLEIQRQQ------SD 2469
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
A + A +++ ++ LQ L+ + E L E ++ + +
Sbjct: 2470 HDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL 2529
Query: 531 TKLRTQRDLLTASLERIGPQ--TKVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVAL 586
+ + A LE++ K L + Q+ Q + L A+ EE ++ +
Sbjct: 2530 LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589
Query: 587 REGGAQADPEELQQMRQQ 604
EG + EELQQ+ QQ
Sbjct: 2590 EEG-VRRKQEELQQLEQQ 2606
Score = 35.1 bits (77), Expect = 0.75
Identities = 84/396 (21%), Positives = 152/396 (38%), Gaps = 36/396 (9%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK--QNFEFQQVTSKLKELEYERDSY 278
QA+ + + L +E+ + + E+C + Q +++E Q VT K +LE
Sbjct: 1269 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA-QLEPVASPA 1327
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
K + QS + + + +L + L I L E+ +L + A
Sbjct: 1328 KKPKVQSGS-ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRA--- 1383
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
E + +L+ VE+ LE A AH A A R+A E
Sbjct: 1384 ------EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE-------------LQQRM 1424
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
+ E A + ++ K + + +L +R++ E+ I ++ R R +++
Sbjct: 1425 QEEVVRREEAAVDAQQQKRSIQ-EELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRV 1483
Query: 459 YEKELTVTLCGEEGA-GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV- 516
+L T GA G + L AR ++ E + ++ ++ + EV
Sbjct: 1484 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1543
Query: 517 --TRWREEAEGARRDVTKLRTQRDL-LTA-SLERIGPQTKVLHLTNNPAA--EAQKQISK 570
+R + EAE AR L+ +L L A ER Q +V A AQ+
Sbjct: 1544 LASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEA 1603
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
EL++ + + K A E Q + + Q+R++ E
Sbjct: 1604 ELQSKRASFAE-KTAQLERSLQEEHVAVAQLREEAE 1638
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 56.0 bits (129), Expect = 4e-07
Identities = 113/546 (20%), Positives = 224/546 (41%), Gaps = 47/546 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q ++ + +R ++ + +E++ SL + ++A ED
Sbjct: 635 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA----EDQHLVEMEDTLNKLQ 690
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLK---DKLLEANVSNKDQISEMKKDMDELLQ 221
E KE + L+A +++ + + LK +KLL+ + K SE K +M +L Q
Sbjct: 691 EAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS-SEGKSEMKKLRQ 749
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCT------QLK-NQLEKQNFEFQQVTSKL-KELEY 273
LE A+ +++ L+ E ++S+A T +LK L++ E QV L KEL+
Sbjct: 750 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 809
Query: 274 ERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEEQVHQ 328
++ + + ++ ++ Q+ + + + E++ L ++ LR+ + + + E+ +
Sbjct: 810 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 869
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
++A + ++ ++ E SQL R L+ L A
Sbjct: 870 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKA-NENAS 927
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESLIHRLQKRLLLVT 446
+++ A K+E +K KL+DL + + L+ R T
Sbjct: 928 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT 987
Query: 447 RE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEKS--LQGYRDLIA 498
E + + + L +K L T L G EE +G + L +Q EK+ Q D +
Sbjct: 988 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQ 1047
Query: 499 AHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQRDLLTASLERIGP 549
+ K +LE + + + E + + ++V +L ++LLT +++
Sbjct: 1048 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1107
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPEELQQMRQQLENS 608
K + AA Q S++L A QEE KL L R ++L++ R L N
Sbjct: 1108 FRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ 1163
Query: 609 RIKLKR 614
+++K+
Sbjct: 1164 LLEMKK 1169
Score = 46.4 bits (105), Expect = 3e-04
Identities = 92/551 (16%), Positives = 231/551 (41%), Gaps = 55/551 (9%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
K ++ L+ RV + + ++++ EK+ ++E K V ++ +
Sbjct: 435 KRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 494
Query: 163 KDEFNTAA-KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-------SEMKK 214
+ + + +E L+ + +TD ++I LK+ +++ +I ++ K
Sbjct: 495 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 215 DMDELLQALEGAQSE----VEMLKKELVKQTSRAEQC-TQLKNQLEK----QNFEFQQVT 265
+ + L LE A E + + K +L + +Q +LK K + EF ++
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 614
Query: 266 SKLKEL----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL 321
++++++ ++E ++ ++ Q + A + M L ++ ++ + + +AI +KL
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQDSERAAHAK--EMEALRAKLMKVIKEKENSLEAIRSKLD 672
Query: 322 LEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ---LESWMSAARAHGVESAGALR 376
E H ++ + LQ ++++ E +V + Q ++++ S +A E
Sbjct: 673 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA--TEEKLLDL 730
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
DAL A +++ L+ E++ + K + +T + +E +
Sbjct: 731 DALRKASSEGKSEMKKLRQQLEAA---EKQIKHLEIEKNAESSKASSITRELQGRELKLT 787
Query: 437 RLQKRLLLVTRERDSYRQQL--------DCYEKELTVTLCGEEGAGSVALLSARVQQLEK 488
LQ+ L V++ +++ ++L + E+ ++V +E + + L
Sbjct: 788 NLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 847
Query: 489 SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG 548
L+ R+ +A D A + + ++ + +E+ E ++ K+ ++ L ++
Sbjct: 848 DLEKLRENLA--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN---SSQLTKMN 902
Query: 549 PQTKVLHLTNNPAAEAQKQISKELEAA---QEEIKKLKVALREG---GAQADPEELQQMR 602
+ L L E Q +++K E A Q+ I+ + V + A+ EE +++
Sbjct: 903 DE---LRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELE 959
Query: 603 QQLENSRIKLK 613
++L + K++
Sbjct: 960 RKLSDLEKKME 970
Score = 43.6 bits (98), Expect = 0.002
Identities = 85/454 (18%), Positives = 177/454 (38%), Gaps = 34/454 (7%)
Query: 98 DLIAAKAQITKLESRVNH----QHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L + ++T L+ ++ + T+ KE+QIL +E+ A E+ +R++ + +
Sbjct: 778 ELQGRELKLTNLQENLSEVSQVKETLEKELQIL-KEKFAEASEEAVSVQRSMQETVNKLH 836
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-------LEANVSNK 206
+ + D++A + +EK + +Q+ K+KL ++ + N
Sbjct: 837 QKEEQFNMLSSDLEKLRENLADMEAKF-REKDEREEQLIKAKEKLENDIAEIMKMSGDNS 895
Query: 207 DQISEM-------KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
Q+++M ++D++EL L A L+K + T +AEQ Q +K
Sbjct: 896 SQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ--EAAKKHEE 953
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
E +++ KL +LE + ++ + + K +R + + + E L+ +++L D
Sbjct: 954 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI-LQNLQKTLLDTEDKL 1012
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
E+ L +E L+ Q E K K + M E+ +L D
Sbjct: 1013 KGAREENSGLLQELEELRK-QAE----KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK 1067
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK---NQESLIH 436
++ L + L E K ++ T+++ + +
Sbjct: 1068 QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLS 1127
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEK-ELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
LQ+ + + E R ++ ++K E ++ + S ++ ++ +
Sbjct: 1128 ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1187
Query: 496 LIAAHDPHAHSK--ALESLRNEVTRWREEAEGAR 527
I+ K LE LRNEVT R E A+
Sbjct: 1188 SISITSALLTEKDAELEKLRNEVTVLRGENASAK 1221
Score = 31.9 bits (69), Expect = 6.9
Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
Query: 504 AHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERI----------GPQTK 552
AH+K +E+LR ++ + +E E + + +KL D +E + +
Sbjct: 641 AHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELE 700
Query: 553 VLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
VL N + + +L+A +E++ L ALR+ ++ E++++RQQLE + ++
Sbjct: 701 VLQAKCNEQTKVIDNFTSQLKATEEKLLDLD-ALRKASSEGK-SEMKKLRQQLEAAEKQI 758
Query: 613 KRYSI 617
K I
Sbjct: 759 KHLEI 763
>BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein.
Length = 1291
Score = 56.0 bits (129), Expect = 4e-07
Identities = 100/463 (21%), Positives = 186/463 (40%), Gaps = 42/463 (9%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
EFN ++ H ++ D + + K + L+ + N +I MK ++D+L + L+
Sbjct: 734 EFNKLSERHMHVQLQLDNLRLENEKLLES--KACLQDSYDNLQEI--MKFEIDQLSRNLQ 789
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK--LKELEYER-DSYKD- 280
+ E E LK +L E + N+L Q E ++ +SK LK LE R + K+
Sbjct: 790 NFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKET 849
Query: 281 --WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL-LLEEQVHQLTSRVEALQ 337
+ Q QK ++ EK ++ L + S + + + + ++E + + E +
Sbjct: 850 AKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRSSVCEKTETID 909
Query: 338 PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXX 397
++ EL + K +S E + V+ + D E+
Sbjct: 910 TLKQELKDINCKYNSALVDREESRVLIKKQEVD----ILDLKETLRLRILSEDIERDMLC 965
Query: 398 XXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
H TE++ L K +G L +E+LI LQ +L ++++ Q+ +
Sbjct: 966 EDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKL---NQKKEEVEQKKN 1022
Query: 458 CYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
Y ++ V +A Q K+ ++ +A K LE+ E+
Sbjct: 1023 EYNFKM-------RQLEHVMDSAAEDPQSPKTPPHFQTHLA--------KLLETQEQEIE 1067
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE--LEAA 575
R VTKL R++ A + R+ Q + + N E+Q+ I K L+
Sbjct: 1068 DGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREM---ENLRLESQQLIEKNWLLQGQ 1124
Query: 576 QEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYSIV 618
++IK+ K E Q P+ Q +Q E+ + +L + IV
Sbjct: 1125 LDDIKRQK----ENSDQNHPDNQQLKNEQEESIKERLAKSKIV 1163
Score = 38.3 bits (85), Expect = 0.080
Identities = 53/258 (20%), Positives = 111/258 (43%), Gaps = 29/258 (11%)
Query: 122 EMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
E +L E+ S +E+ + D++ V+D+ + + +T +E KD+ +
Sbjct: 863 EESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRSSVCEKTETIDTLKQELKDINCKY 922
Query: 181 DKEKTD-------LHKQ---IADLKD----KLLEANVSNKDQISEMKKDMDELLQALEGA 226
+ D + KQ I DLK+ ++L ++ ++ ++L E +
Sbjct: 923 NSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEAS 982
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTS----KLKELEYERDSYKDWQ 282
+ +L+ + T + +L+++L ++ E +Q + K+++LE+ DS +
Sbjct: 983 KKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDP 1042
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
KT ++A+L L E+ + D +K LE H +T E + E
Sbjct: 1043 QSPKTPPHFQTHLAKL------LETQEQEIEDGRASKTSLE---HLVTKLNEDREVKNAE 1093
Query: 343 LHEAKVKLSSVES-QLES 359
+ K +L +E+ +LES
Sbjct: 1094 ILRMKEQLREMENLRLES 1111
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 55.6 bits (128), Expect = 5e-07
Identities = 104/470 (22%), Positives = 186/470 (39%), Gaps = 29/470 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L E+E A L EQ + + + ++E
Sbjct: 701 ESRSLSTELFKLK---NAYEEALDQLETVKRENKNL-EQEIADLTEQIAENGKTIHELEK 756
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKDLKA-----NWDKEKTDLHKQIADLKDKLLEANV 203
+ E AA EH++ K + K+++ ++IA+ KD+ +E
Sbjct: 757 SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE-KDEEIEQLK 815
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
N + E M L A +++E LKK++ + E Q + Q + +
Sbjct: 816 RNYQRTVET---MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 872
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLL 321
V +LK+ + D Q K + A L + EV LRA A + L
Sbjct: 873 SVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA---RKL 929
Query: 322 LEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGALRD 377
E+++ RV+ L L K KL + ++S++E AR ++ A+ D
Sbjct: 930 AEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 989
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQESLIH 436
A A +L + V L++ D+A L + E+ I
Sbjct: 990 AAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIR 1048
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELT-VTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
L+ L ++ + L YE+ + +T EE +V L V +L+ ++ Y+
Sbjct: 1049 ELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKR 1108
Query: 496 LIAAHDP--HAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
D +AH ++E+ E A+ A V KLR + T+S
Sbjct: 1109 QAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1158
Score = 52.8 bits (121), Expect = 3e-06
Identities = 106/538 (19%), Positives = 215/538 (39%), Gaps = 31/538 (5%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDM 148
PW KI + A+ K + + + K+ E ++ L E+ + +D+
Sbjct: 56 PWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDL 115
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
+ ++ + K L+A KE T+ + ++ +L +D+
Sbjct: 116 QLQVQAESENLLDAEERCDQLIKAKFQLEAKI-KEVTERAEDEEEINAELTAKKRKLEDE 174
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK- 267
SE+KKD+D+L L + E + ++ T + +L ++ Q+ +
Sbjct: 175 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 234
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR-DAICNKLLLEEQV 326
L +L+ E D + +KT K + +LE + + E+ LR D NK LE +
Sbjct: 235 LDDLQAEEDKV---NSLNKTKSKLEQQVEDLESSLEQ----EKKLRVDLERNKRKLEGDL 287
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD---ALESAL 383
+ L+ + +L E K QL+S + + G++ +++ +E
Sbjct: 288 KLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE 347
Query: 384 GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
E+ L ++A G + + K +E+ +L++ L
Sbjct: 348 EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 407
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYR----DLIAA 499
T + ++ L + +V GE+ + L Q+LEK ++ DL ++
Sbjct: 408 EATLQHEAMVATLRKKHAD-SVAELGEQ----IDNLQRVKQKLEKEKSEFKLEIDDLSSS 462
Query: 500 HDPHAHSKA-LE----SLRNEVTRWREEAEGARRDVTKLRTQRDLL---TASLERIGPQT 551
+ + SKA LE +L ++++ R + E +R +++L TQ+ L L R +
Sbjct: 463 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEK 522
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
+ + + + +A Q ++EL+ EE K K AL Q+ + +R+Q E +
Sbjct: 523 ESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH-ALQSSRHDCDLLREQYEEEQ 579
Score = 44.0 bits (99), Expect = 0.002
Identities = 53/246 (21%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E + E A+L ++H + + D K EF + +
Sbjct: 407 EEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 466
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
K K +L K L+D+L EA N+ E+++ + EL Q+E L ++L ++
Sbjct: 467 SKSKANLEKICRTLEDQLSEARGKNE----EIQRSLSELTTQKSRLQTEAGELSRQLEEK 522
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
S + +QL + F Q T +LK E + K+ + + + C++ L +
Sbjct: 523 ES-------IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDL--LRE 573
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
+ + + L+ A+ +K E + +A+Q + EL EA+ KL+ E
Sbjct: 574 QYEEEQEGKAELQRAL-SKANSEVAQWRTKYETDAIQRTE-ELEEAQEKLAQRLQDSEEQ 631
Query: 361 MSAARA 366
+ A A
Sbjct: 632 VEAVNA 637
Score = 37.1 bits (82), Expect = 0.18
Identities = 101/505 (20%), Positives = 198/505 (39%), Gaps = 53/505 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ RL+ + Q+ + ES V+ ++ EE K L E++K ++
Sbjct: 504 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS 563
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDL-KAN-----W-DKEKTDLHKQIADLKD---KLLE 200
++E A+ + L KAN W K +TD ++ +L++ KL +
Sbjct: 564 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQ 623
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+++Q+ + L + + Q EVE L ++ + S A + + +K E
Sbjct: 624 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 683
Query: 261 FQQVTSKLKELEYERD-SYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
++ +K +E + E + S K+ ++ S K E ++ ++ ++L I +
Sbjct: 684 WK---TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD- 739
Query: 320 LLLEEQVHQLTSRVEALQP--VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD 377
L EQ+ + + L+ Q+EL +A ++L+ E++ AA H E A LR
Sbjct: 740 --LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE------AALEH--EEAKILRI 789
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERDKATGKLNDLTTVRKNQESLI 435
LE EE+ LK Y+R T + VR E++
Sbjct: 790 QLE--------LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAI- 840
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
RL+K++ + D E E+ ++ + A ++ L + QL+ + D
Sbjct: 841 -RLKKKM------------EGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDD 887
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLH 555
+ + A+ R + + E E R + + R L L + ++LH
Sbjct: 888 ALQTQEDLKEQLAIVERRANLL--QAEVEELRATLEQTERARKLAEQELLDSNERVQLLH 945
Query: 556 LTNNPAAEAQKQISKELEAAQEEIK 580
N +K++ +L Q E++
Sbjct: 946 TQNTSLIHTKKKLETDLMQLQSEVE 970
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 55.6 bits (128), Expect = 5e-07
Identities = 86/476 (18%), Positives = 185/476 (38%), Gaps = 22/476 (4%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX---XXXXXXXXXKD 164
KL + + ++++ + L +E K E + R + V++++ KD
Sbjct: 801 KLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD 860
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
+ + + K+ K+ ++KE I DL+ E + Q+ K+ EL ++LE
Sbjct: 861 KLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLE 920
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+ LK EL S EQ Q +N L++ E QQ+ + EL+ + K Q +
Sbjct: 921 KEKEASHQLKLEL---NSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK-QIE 976
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEEQVHQLTSRVEALQP--- 338
+ + ++ + + E E + ++ ++ K +L+ + + LQ
Sbjct: 977 ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFY 1036
Query: 339 -VQLELHEAKVKLSSVESQLESWMS--AARAHGVESAGALRDALESALGXXXXXXXXXXX 395
+ EL + L SVE +L + + + + L L++A
Sbjct: 1037 GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ 1096
Query: 396 XXXXXXHLTEEVATLKYERDK----ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
+++ K ++K KL ++ ++ QE I +L + L + + +S
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEE--LKSHKLES 1154
Query: 452 YRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
++ + + + + E G L A V+Q +++ Q +D + + + +E
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEK 1214
Query: 512 LRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
+ +E+ G ++ +TA E +G K + +E +KQ
Sbjct: 1215 EAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
Score = 54.4 bits (125), Expect = 1e-06
Identities = 130/569 (22%), Positives = 232/569 (40%), Gaps = 88/569 (15%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKR---DERAVSD 147
+ + L +L+ + TKLE + N + +K +Q ++ + R E ++
Sbjct: 303 KNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHR 362
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW--------DKEK---------TDLHKQ 190
+ K+E + +++ LKA + +KE+ LH +
Sbjct: 363 IHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSK 422
Query: 191 IADLKDKLLEANVSNKDQ---ISEMKKDMDELLQALEGAQSEVE-MLKKELVKQTSRAEQ 246
+ + + +L EA+ K+Q SE D ++ + L+ S +E LK+++ T Q
Sbjct: 423 LLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQ 482
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSY------KDWQTQSKTA--QKRLCNMAEL 298
+ K Q ++Q Q T+KL+E + + + KD + Q+ A QK N++ L
Sbjct: 483 LDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLL 542
Query: 299 EKEVTRLRANERS--LRDAICNKL-----LLEEQVHQLTSRV----EALQPVQLELH--- 344
EKE L A ++ A+ N+L L+++V QLT V E+ + Q LH
Sbjct: 543 EKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQV 602
Query: 345 -EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHL 403
E K L + + ++ S ++ E L ++ E
Sbjct: 603 QEQKAHLRAAQDRVLSLETSVN----ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAK 658
Query: 404 TEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT---RERDSYRQQLDCY- 459
T + A L+ D A L D K+QE ++++ +L VT +++ + QL+ +
Sbjct: 659 TAQRADLQNHLDTAQNALQD-----KHQE--LNKITTQLDQVTAKLQDKQEHCSQLESHL 711
Query: 460 ----EKELTVTLCGEEGAGSVALL-------SARVQQLEKSLQGYRDLIAAHDPHAH--S 506
EK L++ EE G + L A +Q + LQ R L + A S
Sbjct: 712 KEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELS 771
Query: 507 KALE-------SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLH--LT 557
K LE S R ++ + E E ++ +TK ++ +L E + +TK+ H L
Sbjct: 772 KQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELN 831
Query: 558 N---NPAAEAQKQISKELEAAQEEIKKLK 583
N E QK + E EA E+ +K
Sbjct: 832 NRIQTTVTELQK-VKMEKEALMTELSTVK 859
Score = 49.2 bits (112), Expect = 4e-05
Identities = 87/532 (16%), Positives = 203/532 (38%), Gaps = 27/532 (5%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
+++ + + +L S++N ++ I + + L+ +D+++
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 159 XXXXKDEFNTAAKEHKDLKANW-DKEK--TDLHKQIADLKDKLLEANVSNKDQISEMKKD 215
E N + + A DK++ + L + + K+K L ++ ++KK
Sbjct: 676 LQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 216 MDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYER 275
+ L+ + ++ L+++ T + T+L QLE + L++
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 276 DSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+S K T+ + ++ L E + T+++ E + R ++ V +L
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR--------IQTTVTELQKVKME 847
Query: 336 LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD------ALESALGXXXXX 389
+ + EL K KLS V L++ S + A+ D L+ L
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMEN 907
Query: 390 XXXXXXXXXXXXHLTEEVA-TLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+E + LK E + +L K E +LQ + + +
Sbjct: 908 TLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQS 967
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHAHS 506
+ ++Q++ + EL + + + + L ++ Q + L ++ I+ ++
Sbjct: 968 SEQKKKQIEALQGELKIAVLQKTELEN--KLQQQLTQAAQELAAEKEKISVLQNNYEKSQ 1025
Query: 507 KALESLRNEVTRWREEAEGARRDV----TKLRTQRDLLTASLERIGPQTKVLHLTNNPAA 562
+ + L+++ E R+D+ KL ++ L ++ +IG Q K++ A
Sbjct: 1026 ETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
++ +K+ + QE K L+ +E + + E + + + E IK ++
Sbjct: 1086 TLEQDSAKKEQQLQERCKALQDIQKEKSLK-EKELVNEKSKLAEIEEIKCRQ 1136
Score = 45.2 bits (102), Expect = 7e-04
Identities = 44/237 (18%), Positives = 109/237 (45%), Gaps = 11/237 (4%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQ-HKRDERAVSDME 149
+ + L+ +L A Q T+LE+++ Q T + ++ E+EK S+++ +++ + ++
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQLT-QAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ + + ++ + + + + Q L +L A + +
Sbjct: 1033 SDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQ-NKLIQELKTAKATLEQDS 1091
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++ ++ + E +AL+ Q E + +KELV + S+ + ++K + EK E ++ +LK
Sbjct: 1092 AKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEK---EITKLNEELK 1148
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
++ +S K+ Q + EL+ + L+A ++ N+ +L++QV
Sbjct: 1149 --SHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKA---AVEQEKRNQQILKDQV 1200
Score = 33.5 bits (73), Expect = 2.3
Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 10/165 (6%)
Query: 121 KEMQILFEEEKASLIEQHK-RDERAVS----DMEDXXXXXXXXXXXXKDEFNTAAKEHKD 175
KE +++ E+ K + IE+ K R E+ ++ +++ KD ++ +
Sbjct: 1115 KEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLE 1174
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LK 234
L+ D K + ++ + ++L+ V +++ E+KK+ E L E E+ +K
Sbjct: 1175 LQGKADSLKAAVEQEKRN--QQILKDQVKKEEE--ELKKEFIEKEAKLHSEIKEKEVGMK 1230
Query: 235 KELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
K + Q T L L E+Q ++ ELE + D +
Sbjct: 1231 KHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLR 1275
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 55.6 bits (128), Expect = 5e-07
Identities = 113/546 (20%), Positives = 224/546 (41%), Gaps = 47/546 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q ++ + +R ++ + +E++ SL + ++A ED
Sbjct: 681 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA----EDQHLVEMEDTLNKLQ 736
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLK---DKLLEANVSNKDQISEMKKDMDELLQ 221
E KE + L+A +++ + + LK +KLL+ + K SE K +M +L Q
Sbjct: 737 EAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS-SEGKSEMKKLRQ 795
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCT------QLK-NQLEKQNFEFQQVTSKL-KELEY 273
LE A+ +++ L+ E ++S+A T +LK L++ E QV L KEL+
Sbjct: 796 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 855
Query: 274 ERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEEQVHQ 328
++ + + ++ ++ Q+ + + + E++ L ++ LR+ + + + E+ +
Sbjct: 856 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 915
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
++A + ++ ++ E SQL R L+ L A
Sbjct: 916 EEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKE-RDVEELQLKLTKA-NENAS 973
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESLIHRLQKRLLLVT 446
+++ A K+E +K KL+DL + + L+ R T
Sbjct: 974 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT 1033
Query: 447 RE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEKS--LQGYRDLIA 498
E + + + L +K L T L G EE +G + L +Q EK+ Q D +
Sbjct: 1034 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQ 1093
Query: 499 AHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQRDLLTASLERIGP 549
+ K +LE + + + E + + ++V +L ++LLT +++
Sbjct: 1094 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1153
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPEELQQMRQQLENS 608
K + AA Q S++L A QEE KL L R ++L++ R L N
Sbjct: 1154 FRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ 1209
Query: 609 RIKLKR 614
+++K+
Sbjct: 1210 LLEMKK 1215
Score = 43.2 bits (97), Expect = 0.003
Identities = 85/454 (18%), Positives = 177/454 (38%), Gaps = 34/454 (7%)
Query: 98 DLIAAKAQITKLESRVNH----QHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L + ++T L+ ++ + T+ KE+QIL +E+ A E+ +R++ + +
Sbjct: 824 ELQGRELKLTNLQENLSEVSQVKETLEKELQIL-KEKFAEASEEAVSVQRSMQETVNKLH 882
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-------LEANVSNK 206
+ + D++A + +EK + +Q+ K+KL ++ + N
Sbjct: 883 QKEEQFNMLSSDLEKLRENLADMEAKF-REKDEREEQLIKAKEKLENDIAEIMKMSGDNP 941
Query: 207 DQISEM-------KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
Q+++M ++D++EL L A L+K + T +AEQ Q +K
Sbjct: 942 SQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ--EAAKKHEE 999
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
E +++ KL +LE + ++ + + K +R + + + E L+ +++L D
Sbjct: 1000 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI-LQNLQKTLLDTEDKL 1058
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
E+ L +E L+ Q E K K + M E+ +L D
Sbjct: 1059 KGAREENSGLLQELEELRK-QAE----KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK 1113
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK---NQESLIH 436
++ L + L E K ++ T+++ + +
Sbjct: 1114 QTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLS 1173
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEK-ELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
LQ+ + + E R ++ ++K E ++ + S ++ ++ +
Sbjct: 1174 ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1233
Query: 496 LIAAHDPHAHSK--ALESLRNEVTRWREEAEGAR 527
I+ K LE LRNEVT R E A+
Sbjct: 1234 SISITSALLTEKDAELEKLRNEVTVLRGENASAK 1267
Score = 41.5 bits (93), Expect = 0.009
Identities = 98/470 (20%), Positives = 203/470 (43%), Gaps = 51/470 (10%)
Query: 174 KDLKANWDKEKTDLHK---QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE- 229
+ L A D E+ ++ K + +++ +L A + + E++ MD+L +E A E
Sbjct: 365 EQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREK 424
Query: 230 VEML------KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
VE+L K+++ R E+ + K LE+++ + + +LE+ R K+ +
Sbjct: 425 VELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHAR--IKELE- 481
Query: 284 QSKTAQKRLCNMAELEKEVTRLRA-NERSLRDAICNKLLLE-EQVHQLTSRVEALQPVQL 341
QS +K + + E E TR+ +E+S + L L ++V +L R+E+ +P
Sbjct: 482 QSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG- 540
Query: 342 ELHEAKVKLSSVE--SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ + LS ++ S L+ + R +L++ +
Sbjct: 541 ---DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAR---EETHQKEIKALYTA 594
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDC 458
L++E +LK + + A + +D+ + K++ E+ I Q+ + + S+ + L
Sbjct: 595 TEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM---EELKVSFSKGLGT 651
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
E E + + Q ++LQ +D A AH+K +E+LR ++ +
Sbjct: 652 ETAEFA------ELKTQIEKMRLDYQHEIENLQNQQDSERA----AHAKEMEALRAKLMK 701
Query: 519 WREEAEGARRDV-TKLRTQRDLLTASLERI----------GPQTKVLHLTNNPAAEAQKQ 567
+E E + + +KL D +E + +VL N +
Sbjct: 702 VIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDN 761
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYSI 617
+ +L+A +E++ L ALR+ ++ E++++RQQLE + ++K I
Sbjct: 762 FTSQLKATEEKLLDLD-ALRKASSEGK-SEMKKLRQQLEAAEKQIKHLEI 809
Score = 38.7 bits (86), Expect = 0.060
Identities = 83/482 (17%), Positives = 203/482 (42%), Gaps = 54/482 (11%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-------SEMKKDMDELLQAL 223
+E L+ + +TD ++I LK+ +++ +I ++ K+ + L L
Sbjct: 550 QEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL 609
Query: 224 EGAQSE----VEMLKKELVKQTSRAEQC-TQLKNQLEK----QNFEFQQVTSKLKEL--- 271
E A E + + K +L + +Q +LK K + EF ++ ++++++
Sbjct: 610 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD 669
Query: 272 -EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH--Q 328
++E ++ ++ Q + A + M L ++ ++ + + +AI +KL E H +
Sbjct: 670 YQHEIENLQNQQDSERAAHAK--EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 727
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQ---LESWMSAARAHGVESAGALRDALESALGX 385
+ + LQ ++++ E +V + Q ++++ S +A E DAL A
Sbjct: 728 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA--TEEKLLDLDALRKASSE 785
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+++ L+ E++ + K + +T + +E + LQ+ L V
Sbjct: 786 GKSEMKKLRQQLEAA---EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEV 842
Query: 446 TRERDSYRQQL--------DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI 497
++ +++ ++L + E+ ++V +E + + L L+ R+ +
Sbjct: 843 SQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL 902
Query: 498 AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
A D A + + ++ + +E+ E ++ K+ + L ++ + L L
Sbjct: 903 A--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN---PSQLTKMNDE---LRLK 954
Query: 558 NNPAAEAQKQISKELEAA---QEEIKKLKVALREG---GAQADPEELQQMRQQLENSRIK 611
E Q +++K E A Q+ I+ + V + A+ EE +++ ++L + K
Sbjct: 955 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1014
Query: 612 LK 613
++
Sbjct: 1015 ME 1016
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 55.6 bits (128), Expect = 5e-07
Identities = 121/556 (21%), Positives = 219/556 (39%), Gaps = 52/556 (9%)
Query: 90 WETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK----ASLIEQHKRDERAV 145
W + L L + + + +LE R+ Q T + +Q EEE+ ++L + E+
Sbjct: 868 WHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKER 927
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN 205
+ + + ++ K K + L Q+ + + +L EA +
Sbjct: 928 VSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQH 987
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
+D ++ ++++ LLQ Q +VE LK +LV Q Q +++++ E Q+
Sbjct: 988 RDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ---EVQEKLRETQEYN 1044
Query: 266 SKLKELEYERDSY------KD-----WQTQSKTAQKRLC----NMAELEKEVTRLRANER 310
KELE E+ S K+ Q Q+ L +M E + E L A
Sbjct: 1045 RIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQME 1104
Query: 311 SLRDAICNKLL-LEEQVHQLTSRVEALQPVQLEL------HEAK-----VKLSSVESQLE 358
LR + K Q QL +EA + +L EAK ++L S ESQLE
Sbjct: 1105 LLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLHLRLRSTESQLE 1164
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
+ + + A A +L SAL V L+ +++ A
Sbjct: 1165 ALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGAR 1224
Query: 419 G--KLNDLTTVRKNQ--ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAG 474
K L T + S + +L + L + RD R Q+ E+ LT T
Sbjct: 1225 SLFKRGPLLTALSAEAVASALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDT------EA 1278
Query: 475 SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLR 534
+ + +Q L++ L ++ + + +S E + T ++ R ++ ++
Sbjct: 1279 EKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338
Query: 535 TQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVA--LREGG 590
Q R+LL A+ E + Q V HL EA+ Q S +E+++ + A L+
Sbjct: 1339 AQGERELLQAAKENLTAQ--VEHL-QAAVVEARAQAS-AAGILEEDLRTARSALKLKNEE 1394
Query: 591 AQADPEELQQMRQQLE 606
+++ E Q +++Q E
Sbjct: 1395 VESERERAQALQEQGE 1410
Score = 52.4 bits (120), Expect = 5e-06
Identities = 107/570 (18%), Positives = 235/570 (41%), Gaps = 60/570 (10%)
Query: 88 SPWETKR--LKIDLIAAKAQITKLESRVNHQHTIRKEMQ---ILFEEEKASLIEQHKRDE 142
S WE K+ L+ +L+ + L+SR+ R E Q L + K +L Q + +
Sbjct: 1302 SKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQ 1361
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTA--AKEHKDLKANWDKEKTDLHKQIADLK---DK 197
AV + +++ TA A + K+ + ++E+ ++ +LK K
Sbjct: 1362 AAVVEAR----AQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 198 LLEANVS--------NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
L+ N++ ++++ ++ + EL + E ++ +E+L +L K+ + +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQE 1477
Query: 250 LKNQLEKQNFEFQQVTSKLKELEYE--------RDSYKDWQTQSKTAQKRLCNMAELEKE 301
+LEK + + ++E E + R+ KD +TQ + +L + + ++
Sbjct: 1478 QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKDRETQRNVLEHQLLELEKKDQM 1537
Query: 302 VTRLRANERSLRDAI----CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
+ R + L+ + C L LEE H++ + + ++ ++ + +V L+ + L
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 358 ES-----WMSAARAHGVES-AGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
E +++ H +ES + L L+ HLT+++
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRD 1657
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
E ++ L R Q ++ +++ L RER ++L +++L + EE
Sbjct: 1658 QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERG---RELTT-QRQL-MQERAEE 1712
Query: 472 GAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
G G ++ ++ L+ + H H L+ L++++ + + + +
Sbjct: 1713 GKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHE--LQELKDQLEQQLQGLHRKVGETS 1770
Query: 532 KLRTQRD----LLTASLERIGPQTKV----LHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
L +QR+ +L L+ Q ++ L + A A Q +ELEA Q+E ++
Sbjct: 1771 LLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQ-- 1828
Query: 584 VALREGGAQADPEELQQMRQQLENSRIKLK 613
+G + E+ ++ LE + + LK
Sbjct: 1829 ---AQGQEERVKEKADALQGALEQAHMTLK 1855
Score = 46.4 bits (105), Expect = 3e-04
Identities = 97/460 (21%), Positives = 188/460 (40%), Gaps = 38/460 (8%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
++++ +LH + + +++L E + + + SE ++ L +ALE E E+L++E +
Sbjct: 508 EEQQEELHLAVRE-RERLQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEV 566
Query: 241 T---SRAEQ----CTQLKNQLEKQNFEFQQVTSKL----KELEYERDSYKDWQTQSKTAQ 289
T +RAEQ + +N L+ + + + KL + L ++ Q +
Sbjct: 567 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEEN 626
Query: 290 KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVK 349
+ +C+ E ++ A + L +A + L E+ L ++++ + EL
Sbjct: 627 QSVCSRMEAAEQAR--NALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD 684
Query: 350 LSSVESQLESWMSAARAHGVESAGALRDAL--ESALGXXXXXXXXXXXXXXXXXHLTEEV 407
+ + +++ +S +R H E+A + L E+ EV
Sbjct: 685 IQEEKEEIQKKLSESR-HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEV 743
Query: 408 ATLKYERDK--ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
ERD+ +L L++ ++ ES + Q++ ++ + Q+ TV
Sbjct: 744 RLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQ------TV 797
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
T E G V L + + RD A A + +L + +E
Sbjct: 798 TQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQ 857
Query: 526 ARRDVTKLRT--QRDLLTA--SLERIGPQTKVL---HLTNNPAAEAQKQISK-ELEAA-- 575
R K R+ Q++L A SLER + ++ T A +AQ++ + + E+A
Sbjct: 858 LREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALC 917
Query: 576 --QEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
Q E +K +V+L E Q +EL QQLE R +K
Sbjct: 918 QMQLETEKERVSLLETLLQTQ-KELADASQQLERLRQDMK 956
Score = 45.6 bits (103), Expect = 5e-04
Identities = 46/192 (23%), Positives = 93/192 (48%), Gaps = 9/192 (4%)
Query: 171 KEHKDLKANWDKEKT----DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
KE L+ W+KE++ +L K + L+ + +E + K+Q +EM+ + + A
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 227 QSEVEMLKKELVKQ-TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY-ERDSYKDWQTQ 284
+S + ++ E K+ S E Q + +L + + +++ +K + E+++ QTQ
Sbjct: 913 ESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ 972
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+ AQ+ L A ++ L A + + +K+ L++QV L S++ A Q L
Sbjct: 973 LQEAQRELKEAARQHRD--DLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQ-RLV 1029
Query: 345 EAKVKLSSVESQ 356
E +V+ E+Q
Sbjct: 1030 EQEVQEKLRETQ 1041
Score = 45.2 bits (102), Expect = 7e-04
Identities = 48/203 (23%), Positives = 98/203 (48%), Gaps = 16/203 (7%)
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCT 248
++I L+ +L EA + + ++ +DE +AL E+E L++E +Q ++ ++
Sbjct: 1778 QEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQE--QQQAQGQE-E 1834
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC----NMAELEKEVTR 304
++K + + +Q LKE E +K+ Q++ ++ L + LE+ +
Sbjct: 1835 RVKEKADALQGALEQAHMTLKERHGELQDHKE---QARRLEEELAVEGRRVQALEEVLGD 1891
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSA 363
LRA R A+ L L++Q + E + +Q +A+ L + +LE+ +
Sbjct: 1892 LRAESREQEKAL---LALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Query: 364 ARA--HGVESAGALRDALESALG 384
+++ H E+A A +AL+ ALG
Sbjct: 1949 SQSSRHQEEAARARAEALQEALG 1971
Score = 44.4 bits (100), Expect = 0.001
Identities = 80/412 (19%), Positives = 163/412 (39%), Gaps = 29/412 (7%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K + ++ + K+ L+ + + ++ +++D +L L+G S E+L+ L +
Sbjct: 718 KRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQ 777
Query: 242 SRAEQCTQLKNQLEKQNFEFQQ----VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
+ + + QLE Q Q + +++ L+ E D+ + Q + A R AE
Sbjct: 778 QQNSVIDEPQGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAE 837
Query: 298 LEKEVT---RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
E + + A+E+ + + + K E HQ +AL+ ++ E E +++L +
Sbjct: 838 QEGKTALEQQKAAHEKEV-NQLREKWEKERSWHQ-QELAKALESLEREKMELEMRLKEQQ 895
Query: 355 SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATL-KYE 413
+++E+ + ++ AL + L L + L +
Sbjct: 896 TEMEAIQAQREEERTQAESAL---CQMQLETEKERVSLLETLLQTQKELADASQQLERLR 952
Query: 414 RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA 473
+D KL + T Q L Q+ L R+ +R L ++E + L +
Sbjct: 953 QDMKVQKLKEQETTGILQTQL-QEAQRELKEAARQ---HRDDLAALQEESSSLLQDKMD- 1007
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT-- 531
L +V+ L+ L D + K E+ E R ++E E + +T
Sbjct: 1008 -----LQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET--QEYNRIQKELEREKASLTLS 1060
Query: 532 -KLRTQRDLLTASLERIGPQ-TKVLHLTNNPAAEAQKQISKELEAAQEEIKK 581
+ QR L+ + I Q L A QK++S ++E ++E+K+
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
Score = 42.3 bits (95), Expect = 0.005
Identities = 95/408 (23%), Positives = 162/408 (39%), Gaps = 40/408 (9%)
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
E++K+ E Q L +S+ ++ K EL R + + L Q +KQN +++++ L+E
Sbjct: 255 ELEKEAHERSQELIQLKSQGDLEKAEL---QDRVTELSALLTQSQKQNEDYEKMIKALRE 311
Query: 271 ----LEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ 325
LE + + S+ AQ+ ++ ++ K++T++ E D I LE
Sbjct: 312 TVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEE---GDNIAQGSGLENS 368
Query: 326 VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
+ +L S + + Q + +A L+ V S L R V+ LR L
Sbjct: 369 L-ELESSIFS----QFDYQDADKALTLVRSVL-----TRRRQAVQD---LRQQLAGCQEA 415
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
L + + L ERD G+ DL + + L K L+
Sbjct: 416 VNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDL-------QGEVDSLSKERELL 468
Query: 446 TRERDSYRQQLDCYEKE---LTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHD 501
+ R+ RQQL+ E+E L + G A QQ E L R+ +
Sbjct: 469 QKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML 528
Query: 502 PHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
+K ESL +E+ RE E + LR ++ +TA+L R L + N
Sbjct: 529 MGLEAKQSESL-SELITLREALESIHLEGELLRQEQTEVTAALARAEQSIAELSSSENTL 587
Query: 562 AEAQKQI---SKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
+ + +L A E + KV L + Q + EE Q + ++E
Sbjct: 588 KTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLE-EENQSVCSRME 634
Score = 39.1 bits (87), Expect = 0.046
Identities = 89/456 (19%), Positives = 193/456 (42%), Gaps = 32/456 (7%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
A+E +LK + + D ++ +D+ LEA + Q ++ + E AL+GA +
Sbjct: 1790 AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQ 1849
Query: 230 VEM-LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTA 288
M LK+ + EQ +L+ +L + Q + L +L E Q ++ A
Sbjct: 1850 AHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE----QEKALLA 1905
Query: 289 QKRLCNMAELEKEVTRLRANERSLRDA-ICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
++ C E EV R+L+D+ + + +L+E+ +L + Q + + A+
Sbjct: 1906 LQQQCAEQAQEHEV-----ETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 348 VKLSSVESQL---ESWMSAARAHGVESAGALR--DALESALGXXXXXXXXXXXXXXXXXH 402
+ +++ L + + H +E A R +A + L
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 403 LTE---EVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
+ E + L+Y+ D +L + + E L H+ ++ LL + + R Q +
Sbjct: 2021 IQEGEIQDQDLRYQED--VQQLQQ--ALAQRDEELRHQQEREQLL--EKSLAQRVQENMI 2074
Query: 460 EKELTVTLCGEEGAGSVALLSARVQQLEKSL-QGYRDLIAAHDPHAHSKALESLRNEVTR 518
+++ + L EE + L V++L+ +L Q ++++ + + LE+L +
Sbjct: 2075 QEKQNLGLEREE--EEIRGLHQSVRELQLTLAQKEQEILELRETQQRNN-LEALPHSHKT 2131
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
E + + D + R QR+L L+ QT+ + A+ + +A+
Sbjct: 2132 SPMEEQSLKLDSLEPRLQREL--ERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSS 2189
Query: 579 IKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
++++ + L+ + D E+ Q+++ +LE +R L++
Sbjct: 2190 LQEVAMFLQASVLERDSEQ-QRLQDELELTRRALEK 2224
Score = 33.5 bits (73), Expect = 2.3
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 2/136 (1%)
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
LE SL+ + + D KAL +R+ +TR R+ + R+ + + +LL +
Sbjct: 365 LENSLELESSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHD 424
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQL 605
+ + K L + ++ + Q E+ L RE Q EEL+Q + L
Sbjct: 425 QWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-RE-LLQKAREELRQQLEVL 482
Query: 606 ENSRIKLKRYSIVLVL 621
E +L+R ++ L L
Sbjct: 483 EQEAWRLRRVNVELQL 498
>AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2
protein.
Length = 1388
Score = 55.6 bits (128), Expect = 5e-07
Identities = 100/463 (21%), Positives = 186/463 (40%), Gaps = 42/463 (9%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
EFN ++ H ++ D + + K + L+ + N +I MK ++D+L + L+
Sbjct: 831 EFNKLSERHMHVQLQLDNLRLENEKLLES--KACLQDSYDNLQEI--MKFEIDQLSRNLQ 886
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK--LKELEYER-DSYKD- 280
+ E E LK +L E + N+L Q E ++ +SK LK LE R + K+
Sbjct: 887 NFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKET 946
Query: 281 --WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL-LLEEQVHQLTSRVEALQ 337
+ Q QK ++ EK ++ L + S + + + + ++E + + E +
Sbjct: 947 AKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETID 1006
Query: 338 PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXX 397
++ EL + K +S E + V+ + D E+
Sbjct: 1007 TLKQELKDINCKYNSALVDREESRVLIKKQEVD----ILDLKETLRLRILSEDIERDMLC 1062
Query: 398 XXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
H TE++ L K +G L +E+LI LQ +L ++++ Q+ +
Sbjct: 1063 EDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKL---NQKKEEVEQKKN 1119
Query: 458 CYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
Y ++ V +A Q K+ ++ +A K LE+ E+
Sbjct: 1120 EYNFKM-------RQLEHVMDSAAEDPQSPKTPPHFQTHLA--------KLLETQEQEIE 1164
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE--LEAA 575
R VTKL R++ A + R+ Q + + N E+Q+ I K L+
Sbjct: 1165 DGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREM---ENLRLESQQLIEKNWLLQGQ 1221
Query: 576 QEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYSIV 618
++IK+ K E Q P+ Q +Q E+ + +L + IV
Sbjct: 1222 LDDIKRQK----ENSDQNHPDNQQLKNEQEESIKERLAKSKIV 1260
Score = 38.3 bits (85), Expect = 0.080
Identities = 53/258 (20%), Positives = 111/258 (43%), Gaps = 29/258 (11%)
Query: 122 EMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
E +L E+ S +E+ + D++ V+D+ + + +T +E KD+ +
Sbjct: 960 EESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKY 1019
Query: 181 DKEKTD-------LHKQ---IADLKD----KLLEANVSNKDQISEMKKDMDELLQALEGA 226
+ D + KQ I DLK+ ++L ++ ++ ++L E +
Sbjct: 1020 NSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEAS 1079
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTS----KLKELEYERDSYKDWQ 282
+ +L+ + T + +L+++L ++ E +Q + K+++LE+ DS +
Sbjct: 1080 KKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDP 1139
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
KT ++A+L L E+ + D +K LE H +T E + E
Sbjct: 1140 QSPKTPPHFQTHLAKL------LETQEQEIEDGRASKTSLE---HLVTKLNEDREVKNAE 1190
Query: 343 LHEAKVKLSSVES-QLES 359
+ K +L +E+ +LES
Sbjct: 1191 ILRMKEQLREMENLRLES 1208
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 55.2 bits (127), Expect = 7e-07
Identities = 105/473 (22%), Positives = 191/473 (40%), Gaps = 35/473 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L E+E A L EQ + + + ++E
Sbjct: 619 ESRSLSTELFKLK---NAYEEALDQLETVKRENKNL-EQEIADLTEQIAENGKTIHELEK 674
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKDLKA-----NWDKEKTDLHKQIADLKDKLLEANV 203
+ E AA EH++ K + K+++ ++IA+ KD+ +E
Sbjct: 675 SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE-KDEEIEQLK 733
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
N + E M L A +++E LKK++ + E Q + Q + +
Sbjct: 734 RNYQRTVET---MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 790
Query: 263 QVTSKLKELEYERDS----YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
V +LK+ + D +D + Q ++R N+ L+ EV LRA A
Sbjct: 791 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERR-ANL--LQAEVEELRATLEQTERA--- 844
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGA 374
+ L E+++ RV+ L L K KL + ++S++E AR ++ A
Sbjct: 845 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 904
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A +L + V L++ D+A L + E+
Sbjct: 905 ITDAAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 963
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELT-VTLCGEEGAGSVALLSARVQQLEKSLQG 492
I L+ L ++ + L YE+ + +T EE +V L V +L+ ++
Sbjct: 964 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1023
Query: 493 YRDLIAAHDP--HAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Y+ D +AH ++E+ E A+ A V KLR + T+S
Sbjct: 1024 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1076
Score = 50.8 bits (116), Expect = 1e-05
Identities = 92/445 (20%), Positives = 184/445 (41%), Gaps = 30/445 (6%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KE T+ + ++ +L +D+ SE+KKD+D+L L + E + ++ T
Sbjct: 66 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 125
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSK-LKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+ +L ++ Q+ + L +L+ E D + +KT K + +LE
Sbjct: 126 EELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKV---NSLNKTKSKLEQQVEDLES 182
Query: 301 EVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
+ + E+ LR D NK LE + + L+ + +L E K QL+S
Sbjct: 183 SLEQ----EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQS 238
Query: 360 WMSAARAHGVESAGALRD---ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
+ + G++ +++ +E E+ L ++
Sbjct: 239 KVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE 298
Query: 417 ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV 476
A G + + K +E+ +L++ L T + ++ L + +V GE+ +
Sbjct: 299 AGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHAD-SVAELGEQ----I 353
Query: 477 ALLSARVQQLEKSLQGYR----DLIAAHDPHAHSKA-LE----SLRNEVTRWREEAEGAR 527
L Q+LEK ++ DL ++ + + SKA LE +L ++++ R + E +
Sbjct: 354 DNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQ 413
Query: 528 RDVTKLRTQRDLL---TASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
R +++L TQ+ L L R + + + + + +A Q ++EL+ EE K K
Sbjct: 414 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 473
Query: 585 ALREGGAQADPEELQQMRQQLENSR 609
AL Q+ + +R+Q E +
Sbjct: 474 ALAH-ALQSSRHDCDLLREQYEEEQ 497
Score = 49.2 bits (112), Expect = 4e-05
Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 14/199 (7%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD-E 218
KDE + + K+L+ +EK DL Q+ + LL+A DQ+ + K ++ +
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE-ERCDQLIKAKFQLEAK 64
Query: 219 LLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE-------KQNFEFQQVTSKLKEL 271
+ + E A+ E E+ + K+ ++C++LK ++ K E +K+K L
Sbjct: 65 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 124
Query: 272 EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
E +T +K +++ ++ + L+A E + K LE+QV L S
Sbjct: 125 TEELSGLD--ETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 332 RVEALQPVQLELHEAKVKL 350
+E + ++++L K KL
Sbjct: 183 SLEQEKKLRVDLERNKRKL 201
Score = 45.6 bits (103), Expect = 5e-04
Identities = 54/246 (21%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E + E A+L ++H + + D K EF + +
Sbjct: 325 EEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 384
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
K K +L K L+D+L EA N+ E+++ + EL Q+E L ++L ++
Sbjct: 385 SKSKANLEKICRTLEDQLSEARGKNE----EIQRSLSELTTQKSRLQTEAGELSRQLEEK 440
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
S + +QL + F Q T +LK E + K+ + + + C++ L +
Sbjct: 441 ES-------IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDL--LRE 491
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
+ + + L+ A+ +K E + +A+Q + EL EAK KL+ E
Sbjct: 492 QYEEEQEGKAELQRAL-SKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDSEEQ 549
Query: 361 MSAARA 366
+ A A
Sbjct: 550 VEAVNA 555
Score = 44.4 bits (100), Expect = 0.001
Identities = 105/487 (21%), Positives = 198/487 (40%), Gaps = 46/487 (9%)
Query: 142 ERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKL 198
ERA D E+ +DE + K+ DL+ A +KEK ++ +L ++L
Sbjct: 70 ERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 128
Query: 199 LEANVSNKDQISEMKKDMDELLQALEGAQSE---VEMLKKELVKQTSRAEQCTQLKNQLE 255
+ + E K + QAL+ Q+E V L K K + E Q +
Sbjct: 129 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 188
Query: 256 KQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
K + ++ KL+ +L+ ++S D + + +RL + + E +L++ + D
Sbjct: 189 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL---KKKDFEYCQLQS---KVED 242
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA 374
L ++++ +L +R+E L+ E+ + + E Q + A +E
Sbjct: 243 EQTLGLQFQKKIKELQARIEELEE---EIEAERATRAKTEKQRSDY-----ARELEE--- 291
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTE--EVATLKYERDKATGKLNDLTTVRKNQE 432
L + LE A G L E ATL++E AT + +V + E
Sbjct: 292 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 351
Query: 433 SLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL-- 490
I LQ+ + +E+ ++ ++D +L+ ++ E + S A L + LE L
Sbjct: 352 Q-IDNLQRVKQKLEKEKSEFKLEID----DLSSSM--ESVSKSKANLEKICRTLEDQLSE 404
Query: 491 -QGYRDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+G + I + + L++ E++R EE E V++L + T E +
Sbjct: 405 ARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESI---VSQLSRSKQAFTQQTEEL 461
Query: 548 GPQTKVLHLTNNPAAEAQKQISKE---LEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
Q + + N A A + + L EE ++ K L+ ++A+ E+ Q R +
Sbjct: 462 KRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN-SEVAQWRTK 520
Query: 605 LENSRIK 611
E I+
Sbjct: 521 YETDAIQ 527
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 55.2 bits (127), Expect = 7e-07
Identities = 105/473 (22%), Positives = 191/473 (40%), Gaps = 35/473 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L E+E A L EQ + + + ++E
Sbjct: 1474 ESRSLSTELFKLK---NAYEEALDQLETVKRENKNL-EQEIADLTEQIAENGKTIHELEK 1529
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKDLKA-----NWDKEKTDLHKQIADLKDKLLEANV 203
+ E AA EH++ K + K+++ ++IA+ KD+ +E
Sbjct: 1530 SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE-KDEEIEQLK 1588
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
N + E M L A +++E LKK++ + E Q + Q + +
Sbjct: 1589 RNYQRTVET---MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 1645
Query: 263 QVTSKLKELEYERDS----YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
V +LK+ + D +D + Q ++R N+ L+ EV LRA A
Sbjct: 1646 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERR-ANL--LQAEVEELRATLEQTERA--- 1699
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGA 374
+ L E+++ RV+ L L K KL + ++S++E AR ++ A
Sbjct: 1700 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 1759
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A +L + V L++ D+A L + E+
Sbjct: 1760 ITDAAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELT-VTLCGEEGAGSVALLSARVQQLEKSLQG 492
I L+ L ++ + L YE+ + +T EE +V L V +L+ ++
Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
Query: 493 YRDLIAAHDP--HAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Y+ D +AH ++E+ E A+ A V KLR + T+S
Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1931
Score = 52.8 bits (121), Expect = 3e-06
Identities = 106/538 (19%), Positives = 215/538 (39%), Gaps = 31/538 (5%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDM 148
PW KI + A+ K + + + K+ E ++ L E+ + +D+
Sbjct: 829 PWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDL 888
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
+ ++ + K L+A KE T+ + ++ +L +D+
Sbjct: 889 QLQVQAESENLLDAEERCDQLIKAKFQLEAKI-KEVTERAEDEEEINAELTAKKRKLEDE 947
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK- 267
SE+KKD+D+L L + E + ++ T + +L ++ Q+ +
Sbjct: 948 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 1007
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR-DAICNKLLLEEQV 326
L +L+ E D + +KT K + +LE + + E+ LR D NK LE +
Sbjct: 1008 LDDLQAEEDKV---NSLNKTKSKLEQQVEDLESSLEQ----EKKLRVDLERNKRKLEGDL 1060
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD---ALESAL 383
+ L+ + +L E K QL+S + + G++ +++ +E
Sbjct: 1061 KLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE 1120
Query: 384 GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
E+ L ++A G + + K +E+ +L++ L
Sbjct: 1121 EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 1180
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYR----DLIAA 499
T + ++ L + +V GE+ + L Q+LEK ++ DL ++
Sbjct: 1181 EATLQHEAMVATLRKKHAD-SVAELGEQ----IDNLQRVKQKLEKEKSEFKLEIDDLSSS 1235
Query: 500 HDPHAHSKA-LE----SLRNEVTRWREEAEGARRDVTKLRTQRDLL---TASLERIGPQT 551
+ + SKA LE +L ++++ R + E +R +++L TQ+ L L R +
Sbjct: 1236 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEK 1295
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
+ + + + +A Q ++EL+ EE K K AL Q+ + +R+Q E +
Sbjct: 1296 ESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH-ALQSSRHDCDLLREQYEEEQ 1352
Score = 44.0 bits (99), Expect = 0.002
Identities = 53/246 (21%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E + E A+L ++H + + D K EF + +
Sbjct: 1180 EEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 1239
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
K K +L K L+D+L EA N+ E+++ + EL Q+E L ++L ++
Sbjct: 1240 SKSKANLEKICRTLEDQLSEARGKNE----EIQRSLSELTTQKSRLQTEAGELSRQLEEK 1295
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
S + +QL + F Q T +LK E + K+ + + + C++ L +
Sbjct: 1296 ES-------IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDL--LRE 1346
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
+ + + L+ A+ +K E + +A+Q + EL EA+ KL+ E
Sbjct: 1347 QYEEEQEGKAELQRAL-SKANSEVAQWRTKYETDAIQRTE-ELEEAQEKLAQRLQDSEEQ 1404
Query: 361 MSAARA 366
+ A A
Sbjct: 1405 VEAVNA 1410
Score = 37.1 bits (82), Expect = 0.18
Identities = 101/505 (20%), Positives = 198/505 (39%), Gaps = 53/505 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ RL+ + Q+ + ES V+ ++ EE K L E++K ++
Sbjct: 1277 QKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQS 1336
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDL-KAN-----W-DKEKTDLHKQIADLKD---KLLE 200
++E A+ + L KAN W K +TD ++ +L++ KL +
Sbjct: 1337 SRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQ 1396
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+++Q+ + L + + Q EVE L ++ + S A + + +K E
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 261 FQQVTSKLKELEYERD-SYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK 319
++ +K +E + E + S K+ ++ S K E ++ ++ ++L I +
Sbjct: 1457 WK---TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD- 1512
Query: 320 LLLEEQVHQLTSRVEALQP--VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRD 377
L EQ+ + + L+ Q+EL +A ++L+ E++ AA H E A LR
Sbjct: 1513 --LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE------AALEH--EEAKILRI 1562
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK--YERDKATGKLNDLTTVRKNQESLI 435
LE EE+ LK Y+R T + VR E++
Sbjct: 1563 QLE--------LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAI- 1613
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
RL+K++ + D E E+ ++ + A ++ L + QL+ + D
Sbjct: 1614 -RLKKKM------------EGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDD 1660
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLH 555
+ + A+ R + + E E R + + R L L + ++LH
Sbjct: 1661 ALRGQEDLKEQLAIVERRANLL--QAEVEELRATLEQTERARKLAEQELLDSNERVQLLH 1718
Query: 556 LTNNPAAEAQKQISKELEAAQEEIK 580
N +K++ +L Q E++
Sbjct: 1719 TQNTSLIHTKKKLETDLMQLQSEVE 1743
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 178 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 234
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 235 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 291
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 292 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 349
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 350 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 409
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 410 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 469
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 470 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 526
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 527 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 572
Score = 39.9 bits (89), Expect = 0.026
Identities = 95/464 (20%), Positives = 181/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 250 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 308
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 309 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 368
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 369 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 428
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 429 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 488
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 489 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 548
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 549 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 606
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 607 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 664
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K KR
Sbjct: 665 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKKKR 706
Score = 33.9 bits (74), Expect = 1.7
Identities = 56/287 (19%), Positives = 117/287 (40%), Gaps = 26/287 (9%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 391 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 442
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 443 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 500
Query: 293 CNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ K++ + + S+++ +E + Q+ +E + E + +L
Sbjct: 501 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 560
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+E + E + + ++ +ALE +LT ++ +L+
Sbjct: 561 HLEKENE--LLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 618
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQK--RLLLVTRERDSYRQQL 456
E + + +L R+N ESL K +L L +E +S ++QL
Sbjct: 619 KENSQLDEENLEL---RRNVESLKCASMKMAQLQLENKELESEKEQL 662
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 250 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 306
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 307 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 363
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 364 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 421
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 422 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 481
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 482 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 541
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 542 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 598
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 599 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 644
Score = 55.2 bits (127), Expect = 7e-07
Identities = 76/322 (23%), Positives = 148/322 (45%), Gaps = 29/322 (9%)
Query: 47 EGLSNLLTFGKRKSSIGS---VDDVTPDKRLRRDS-SGNGTTAPPSPWETKRLKIDLIAA 102
E L+ ++ +++S I + V D+ + ++ +S + +E +++K +L
Sbjct: 558 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 617
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD--ERAVSDMEDXXXXXXXXXX 160
K + + E N H + KE ++L ++ I K + E+ S++E
Sbjct: 618 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 677
Query: 161 XXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSNKDQISEMKK 214
K+ + + KE+ L D+E +L + + LK K+ + + NK+ SE K+
Sbjct: 678 SFKNLTFQLESLEKENSQL----DEENLELRRNVESLKCASMKMAQLQLENKELESE-KE 732
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ + L+ L+ + + E L E+ Q E +L+ LE N + QQ+ S+L++LE E
Sbjct: 733 QLKKGLELLKASFKKTERL--EVSYQGLDIEN-QRLQKTLENSNKKIQQLESELQDLEME 789
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ + + K + KRL +LEKE L L +K LE++ +L + E
Sbjct: 790 NQTLQKNLEELKISSKRL---EQLEKENKSLEQETSQLEK---DKKQLEKENKRLRQQAE 843
Query: 335 ALQPVQLELHEAKVKLSSVESQ 356
++ LE E VK+ ++E +
Sbjct: 844 -IKDTTLE--ENNVKIGNLEKE 862
Score = 41.1 bits (92), Expect = 0.011
Identities = 84/433 (19%), Positives = 165/433 (38%), Gaps = 44/433 (10%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 463 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 514
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 515 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 572
Query: 293 ----CNMAELEKEVTRLRANERSLRDAIC----NKLLLEEQVHQLTSRVEALQPVQLELH 344
+ ++EKE L + + + K +++++ + E + ++ ELH
Sbjct: 573 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 632
Query: 345 EAKVKLSSVESQLESW-MSAARAHGVESAGALRD----ALESALGXXXXXXXXXXXXXXX 399
+ + ++ ++ + ++ + +E + + L+ L
Sbjct: 633 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 692
Query: 400 XXHLTEEVATLKYERDK---ATGKLNDLTTVRKNQESLIHRLQKRLLLV------TRERD 450
L EE L+ + A+ K+ L K ES +L+K L L+ T +
Sbjct: 693 NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLE 752
Query: 451 SYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
Q LD + L TL E + L + +Q LE Q + + + SK LE
Sbjct: 753 VSYQGLDIENQRLQKTL--ENSNKKIQQLESELQDLEMENQTLQKNL--EELKISSKRLE 808
Query: 511 SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
L E +E +D +L + L E + ++ + K +SK
Sbjct: 809 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 868
Query: 571 ELEAAQEEIKKLK 583
E+ +E +LK
Sbjct: 869 EIGIYKESCVRLK 881
Score = 38.3 bits (85), Expect = 0.080
Identities = 93/464 (20%), Positives = 182/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 322 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 380
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 381 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 440
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 441 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 500
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 501 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 560
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 561 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 620
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 621 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 678
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 679 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 736
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K+++
Sbjct: 737 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQ 778
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 55.2 bits (127), Expect = 7e-07
Identities = 105/473 (22%), Positives = 191/473 (40%), Gaps = 35/473 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L E+E A L EQ + + + ++E
Sbjct: 475 ESRSLSTELFKLK---NAYEEALDQLETVKRENKNL-EQEIADLTEQIAENGKTIHELEK 530
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKDLKA-----NWDKEKTDLHKQIADLKDKLLEANV 203
+ E AA EH++ K + K+++ ++IA+ KD+ +E
Sbjct: 531 SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE-KDEEIEQLK 589
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
N + E M L A +++E LKK++ + E Q + Q + +
Sbjct: 590 RNYQRTVET---MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 646
Query: 263 QVTSKLKELEYERDS----YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
V +LK+ + D +D + Q ++R N+ L+ EV LRA A
Sbjct: 647 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERR-ANL--LQAEVEELRATLEQTERA--- 700
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGA 374
+ L E+++ RV+ L L K KL + ++S++E AR ++ A
Sbjct: 701 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 760
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A +L + V L++ D+A L + E+
Sbjct: 761 ITDAAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 819
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELT-VTLCGEEGAGSVALLSARVQQLEKSLQG 492
I L+ L ++ + L YE+ + +T EE +V L V +L+ ++
Sbjct: 820 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 879
Query: 493 YRDLIAAHDP--HAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Y+ D +AH ++E+ E A+ A V KLR + T+S
Sbjct: 880 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 932
Score = 45.6 bits (103), Expect = 5e-04
Identities = 54/246 (21%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E + E A+L ++H + + D K EF + +
Sbjct: 181 EEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 240
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
K K +L K L+D+L EA N+ E+++ + EL Q+E L ++L ++
Sbjct: 241 SKSKANLEKICRTLEDQLSEARGKNE----EIQRSLSELTTQKSRLQTEAGELSRQLEEK 296
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
S + +QL + F Q T +LK E + K+ + + + C++ L +
Sbjct: 297 ES-------IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDL--LRE 347
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
+ + + L+ A+ +K E + +A+Q + EL EAK KL+ E
Sbjct: 348 QYEEEQEGKAELQRAL-SKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDSEEQ 405
Query: 361 MSAARA 366
+ A A
Sbjct: 406 VEAVNA 411
Score = 41.5 bits (93), Expect = 0.009
Identities = 82/442 (18%), Positives = 184/442 (41%), Gaps = 54/442 (12%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQIS-EMKKDMDELLQALEGAQSEVEMLKKELVK 239
DK++ D + D + L++ V ++ + + +K + EL +E + E+E
Sbjct: 74 DKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIE-------- 125
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
AE+ T+ K EKQ ++ + +L E E TQ + +KR +L
Sbjct: 126 ----AERATRAKT--EKQRSDYARELEELSERLEEAGGVT--STQIELNKKREAEFLKLR 177
Query: 300 KEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH----EAKVKLSSVES 355
+++ ++ + K + V +L +++ LQ V+ +L E K+++ + S
Sbjct: 178 RDLEEATLQHEAMVATLRKK--HADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSS 235
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ES +S ++A+ + L D L A G + ++ L ++
Sbjct: 236 SMES-VSKSKANLEKICRTLEDQLSEARG--------------KNEEIQRSLSELTTQKS 280
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ + +L+ + +ES++ +L + T++ + ++QL+ E+ S
Sbjct: 281 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE--EENKAKNALAHALQSS 338
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE-GARRDVTKLR 534
+Q E+ +G +L +AL +EV +WR + E A + +L
Sbjct: 339 RHDCDLLREQYEEEQEGKAEL---------QRALSKANSEVAQWRTKYETDAIQRTEELE 389
Query: 535 TQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKK---LKVALREGGA 591
+ L L+ Q + ++ + ++++ E+E ++++ L AL +
Sbjct: 390 EAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 449
Query: 592 QADPEELQQMRQQLENSRIKLK 613
D + L + + + E S+ +L+
Sbjct: 450 NFD-KVLAEWKTKCEESQAELE 470
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 55.2 bits (127), Expect = 7e-07
Identities = 89/407 (21%), Positives = 174/407 (42%), Gaps = 28/407 (6%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 178 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 234
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ +++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 235 DELDALREKAVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 291
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 292 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 349
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 350 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 409
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 410 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 469
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 470 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 526
Query: 567 QISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
++SK +E + +IKK +E G +A+ E + + EN ++ K
Sbjct: 527 KLSK-IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 572
Score = 48.0 bits (109), Expect = 1e-04
Identities = 59/258 (22%), Positives = 119/258 (46%), Gaps = 20/258 (7%)
Query: 47 EGLSNLLTFGKRKSSIGS---VDDVTPDKRLRRDS-SGNGTTAPPSPWETKRLKIDLIAA 102
E L+ ++ +++S I + V D+ + ++ +S + +E +++K +L
Sbjct: 486 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 545
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD--ERAVSDMEDXXXXXXXXXX 160
K + + E N H + KE ++L ++ I K + E+ S++E
Sbjct: 546 KEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLD 605
Query: 161 XXKD---EFNTAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSNKDQISEMKK 214
K+ + + KE+ L D+E +L + + LK K+ + + NK+ SE K+
Sbjct: 606 SFKNLTFQLESLEKENSQL----DEENLELRRNVESLKCASMKMAQLQLENKELESE-KE 660
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ + L+ L+ + + E L E+ Q E +L+ LE N + QQ+ S+L++LE E
Sbjct: 661 QLKKGLELLKASFKKTERL--EVSYQGLDIEN-QRLQKTLENSNKKIQQLESELQDLEME 717
Query: 275 RDSYKDWQTQSKTAQKRL 292
+ + + K + KRL
Sbjct: 718 NQTLQKNLEELKISSKRL 735
Score = 38.3 bits (85), Expect = 0.080
Identities = 93/464 (20%), Positives = 182/464 (39%), Gaps = 43/464 (9%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 250 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 308
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 309 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 368
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKV-KLSSVESQL 357
A ++SL + ++LL LE + LT VE L+ +E + +K+ K+ +L
Sbjct: 369 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 428
Query: 358 ESWMSAARAHGVESAGALRDA-------------LESALGX-XXXXXXXXXXXXXXXXHL 403
+ V+ +L++ LE + HL
Sbjct: 429 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHL 488
Query: 404 TEEVATLKYERD-KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYE-- 460
+ V++L+ A ++ D+ K I +L + E+ +++L+ Y+
Sbjct: 489 NQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 548
Query: 461 ----KELTVTLCGEEGAG-----SVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALES 511
+EL L E + L +++E Q +L + K L+S
Sbjct: 549 GERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL--ERENRKLKKTLDS 606
Query: 512 LRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
+N + E E ++ D L +R++ SL+ + L L N ++Q+ K
Sbjct: 607 FKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQLENKELESEKEQLKK 664
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
LE + KK + E Q E Q++++ LENS K+++
Sbjct: 665 GLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQ 706
Score = 33.9 bits (74), Expect = 1.7
Identities = 56/287 (19%), Positives = 117/287 (40%), Gaps = 26/287 (9%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 391 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 442
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKE--------LEYERDSYKDWQTQSKTAQKRL 292
+ C L L K+ + ++ L+E LE E + QT S Q+
Sbjct: 443 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN--QTVSSLRQRSQ 500
Query: 293 CNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ K++ + + S+++ +E + Q+ +E + E + +L
Sbjct: 501 ISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH 560
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+E + E + + ++ +ALE +LT ++ +L+
Sbjct: 561 HLEKENE--LLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE 618
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQK--RLLLVTRERDSYRQQL 456
E + + +L R+N ESL K +L L +E +S ++QL
Sbjct: 619 KENSQLDEENLEL---RRNVESLKCASMKMAQLQLENKELESEKEQL 662
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 54.8 bits (126), Expect = 9e-07
Identities = 112/546 (20%), Positives = 224/546 (41%), Gaps = 47/546 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q ++ + +R ++ + +E++ SL + ++A ED
Sbjct: 670 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA----EDQHLVEMEDTLNKLQ 725
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLK---DKLLEANVSNKDQISEMKKDMDELLQ 221
E KE + L+A +++ + + LK +KLL+ + K SE K +M +L Q
Sbjct: 726 EAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS-SEGKSEMKKLRQ 784
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCT------QLK-NQLEKQNFEFQQVTSKL-KELEY 273
LE A+ +++ L+ E ++S+A T +LK L++ E QV L KEL+
Sbjct: 785 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 844
Query: 274 ERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEEQVHQ 328
++ + + ++ ++ Q+ + + + E++ L ++ LR+ + + + E+ +
Sbjct: 845 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 904
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
++A + ++ ++ E SQL R L+ L A
Sbjct: 905 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKA-NENAS 962
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESLIHRLQKRLLLVT 446
+++ A K+E +K KL+DL + + L+ R T
Sbjct: 963 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT 1022
Query: 447 RE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEKS--LQGYRDLIA 498
E + + + L +K L T L G EE +G + L +Q +K+ Q D +
Sbjct: 1023 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1082
Query: 499 AHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQRDLLTASLERIGP 549
+ K +LE + + + E + + ++V +L ++LLT +++
Sbjct: 1083 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1142
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPEELQQMRQQLENS 608
K + AA Q S++L A QEE KL L R ++L++ R L N
Sbjct: 1143 FRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ 1198
Query: 609 RIKLKR 614
+++K+
Sbjct: 1199 LLEMKK 1204
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/222 (20%), Positives = 100/222 (45%), Gaps = 22/222 (9%)
Query: 98 DLIAAKAQITKLESRVNH----QHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L + ++T L+ ++ + T+ KE+QIL +E+ A E+ +R++ + +
Sbjct: 813 ELQGRELKLTNLQENLSEVSQVKETLEKELQIL-KEKFAEASEEAVSVQRSMQETVNKLH 871
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-------LEANVSNK 206
+ + D++A + +EK + +Q+ K+KL ++ + N
Sbjct: 872 QKEEQFNMLSSDLEKLRENLADMEAKF-REKDEREEQLIKAKEKLENDIAEIMKMSGDNS 930
Query: 207 DQISEM-------KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
Q+++M ++D++EL L A L+K + T +AEQ Q +K
Sbjct: 931 SQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ--EAAKKHEE 988
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E +++ KL +LE + ++ + + K +R + + + E
Sbjct: 989 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE 1030
Score = 41.5 bits (93), Expect = 0.009
Identities = 95/463 (20%), Positives = 201/463 (43%), Gaps = 48/463 (10%)
Query: 174 KDLKANWDKEKTDLHK---QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
+ L A D E+ ++ K + +++ +L A + + E++ MD+L +E A E
Sbjct: 365 EQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREK 424
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQK 290
L +L ++ + E L+ ++E+++ + ++ K LE+ R K+ + QS +K
Sbjct: 425 VELLNQLEEEKRKVED---LQFRVEEESITKGDLETQTK-LEHAR--IKELE-QSLLFEK 477
Query: 291 RLCNMAELEKEVTRLRA-NERSLRDAICNKLLLE-EQVHQLTSRVEALQPVQLELHEAKV 348
+ + E E TR+ +E+S + L L ++V +L R+E+ +P + +
Sbjct: 478 TKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG----DVDM 533
Query: 349 KLSSVE--SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEE 406
LS ++ S L+ + R +L++ + L++E
Sbjct: 534 SLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAR---EETHQKEIKALYTATEKLSKE 590
Query: 407 VATLKYERDKATGKLNDLTTVRKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
+LK + + A + +D+ + K++ E+ I Q+ + + S+ + L E
Sbjct: 591 NESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM---EELKVSFSKGLGTETAEFA- 646
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
E + + Q ++LQ +D A AH+K +E+LR ++ + +E E
Sbjct: 647 -----ELKTQIEKMRLDYQHEIENLQNQQDSERA----AHAKEMEALRAKLMKVIKEKEN 697
Query: 526 ARRDV-TKLRTQRDLLTASLERI----------GPQTKVLHLTNNPAAEAQKQISKELEA 574
+ + +KL D +E + +VL N + + +L+A
Sbjct: 698 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA 757
Query: 575 AQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYSI 617
+E++ L ALR+ ++ E++++RQQLE + ++K I
Sbjct: 758 TEEKLLDLD-ALRKASSEGK-SEMKKLRQQLEAAEKQIKHLEI 798
Score = 39.5 bits (88), Expect = 0.035
Identities = 83/482 (17%), Positives = 204/482 (42%), Gaps = 54/482 (11%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-------SEMKKDMDELLQAL 223
+E L+ + +TD ++I LK+ +++ +I ++ K+ + L L
Sbjct: 539 QEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL 598
Query: 224 EGAQSE----VEMLKKELVKQTSRAEQC-TQLKNQLEK----QNFEFQQVTSKLKEL--- 271
E A E + + K +L + +Q +LK K + EF ++ ++++++
Sbjct: 599 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD 658
Query: 272 -EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH--Q 328
++E ++ ++ Q + A + M L ++ ++ + + +AI +KL E H +
Sbjct: 659 YQHEIENLQNQQDSERAAHAK--EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 716
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQ---LESWMSAARAHGVESAGALRDALESALGX 385
+ + LQ ++++ E +V + Q ++++ S +A E DAL A
Sbjct: 717 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA--TEEKLLDLDALRKASSE 774
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+++ L+ E++ + K + +T + +E + LQ+ L V
Sbjct: 775 GKSEMKKLRQQLEAA---EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEV 831
Query: 446 TRERDSYRQQL--------DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI 497
++ +++ ++L + E+ ++V +E + + L L+ R+ +
Sbjct: 832 SQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL 891
Query: 498 AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
A D A + + ++ + +E+ E ++ K+ ++ L ++ + L L
Sbjct: 892 A--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN---SSQLTKMNDE---LRLK 943
Query: 558 NNPAAEAQKQISKELEAA---QEEIKKLKVALREG---GAQADPEELQQMRQQLENSRIK 611
E Q +++K E A Q+ I+ + V + A+ EE +++ ++L + K
Sbjct: 944 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1003
Query: 612 LK 613
++
Sbjct: 1004 ME 1005
>L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.
Length = 1300
Score = 54.8 bits (126), Expect = 9e-07
Identities = 105/541 (19%), Positives = 231/541 (42%), Gaps = 56/541 (10%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEE--EKASLIEQHKRDE--RAVSDMEDXXXX 154
A K+++ KL++ V+ Q + ++M+ +E EK +E+ + + E+
Sbjct: 709 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 768
Query: 155 XXXXXXXXKDEFNTAAKEHKDLK-ANWDKE-KTDLHKQIADLK--DKLLEANVSNKDQIS 210
K+ + AK++ + A+ +E K +H++ +K ++LLEA +
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 828
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-----------EQCTQLKNQLEKQNF 259
+ +D+ + ++AL+ V++ K + + TS+ EQ +K LE++
Sbjct: 829 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 888
Query: 260 EFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ L++L+ E +S K Q ++ K + ++ E+ L+ E L+
Sbjct: 889 DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL--- 945
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDA 378
+ +L+E+ L+S+ + LQ VQ E K ++ ++ Q S+ H
Sbjct: 946 EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPH----------- 994
Query: 379 LESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRL 438
E L L + V +++R K + + V + ++ +L
Sbjct: 995 -EELLKVISEREKEISGLWNELDSLKDAV---EHQRKKNNERQQQVEAVELEAKEVLKKL 1050
Query: 439 QKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ-------LEKSLQ 491
++ + + SY + L +EK+ + G G+ V +L ++++ L+ +
Sbjct: 1051 FPKVSVPSNL--SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECE 1108
Query: 492 GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT 551
Y+ ++A + K S+ E +W+ + + + + + ++++ LER+ +
Sbjct: 1109 KYKSVLAETE-GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSEN 1167
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
K + N E ++ + ELE A+ E +RE AQ + E L ++R + +N R K
Sbjct: 1168 KDI---ENLRRE-REHLEMELEKAEMERSTYVTEVRELKAQLN-ETLTKLRTE-QNERQK 1221
Query: 612 L 612
+
Sbjct: 1222 V 1222
Score = 54.8 bits (126), Expect = 9e-07
Identities = 108/517 (20%), Positives = 204/517 (39%), Gaps = 51/517 (9%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
+A++ K+ ++ +++E++ L EE ++ K + +++
Sbjct: 818 EAELLKVANKEKTVQDLKQEIKALKEE--IGNVQLEKAQQLSITSKVQELQNLLKGKEEQ 875
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+ +E + AN K DL ++ LK + E N + S + +EL
Sbjct: 876 MNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQ-FEELEIV 934
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L+ ++E++ L+ L ++ S TQL ++ +N F+ +LK+ Y++ S
Sbjct: 935 LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQAS----- 989
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
++ L ++E EKE++ L SL+DA+ E Q + R + ++ V+LE
Sbjct: 990 -SFPPHEELLKVISEREKEISGLWNELDSLKDAV------EHQRKKNNERQQQVEAVELE 1042
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
E KL S + HG E ++ + G H
Sbjct: 1043 AKEVLKKLFPKVSVPSNLSYGEWLHGFEKKA--KECMAGTSGSEEVKVLEHKLKEADEMH 1100
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
++ KY+ +V E ++ +LQ+ V +E + ++ ++D E
Sbjct: 1101 TLLQLECEKYK------------SVLAETEGILQKLQRS---VEQEENKWKVKVD--ESH 1143
Query: 463 LTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
T+ S L R++ K ++ R H KA VT RE
Sbjct: 1144 KTIKQMQSSFTSSEQELE-RLRSENKDIENLR-REREHLEMELEKAEMERSTYVTEVREL 1201
Query: 523 AEGARRDVTKLRTQR--------DLLTA--SLERIGPQTKVLHLTNNPAAEAQKQISKEL 572
+TKLRT++ DL A SLE I Q+K++ + +S E
Sbjct: 1202 KAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELI--QSKIVKAAGDTTVIENSDVSPET 1259
Query: 573 EAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
E++++E + V+L + Q + LQ + QQL +
Sbjct: 1260 ESSEKE--TMSVSLNQTVTQLQ-QLLQAVNQQLTKEK 1293
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/513 (18%), Positives = 220/513 (42%), Gaps = 45/513 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 422 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 481
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 482 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 532
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 533 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 589
Query: 362 SAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKA 417
S A SA L + L + LT EE+ ++
Sbjct: 590 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA---G 474
++ L + Q + H L+K V + D R + + E++ + EE
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM--EEFKILND 705
Query: 475 SVALLSARVQQLEK--SLQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDV 530
L + VQ+L+ S Q +D++ + K L+++ + + ++
Sbjct: 706 QNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 765
Query: 531 TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK---ELEAAQE--EIKKLKVA 585
+RT+ LT ++ + + + E +K I + ++++ +E E + LKVA
Sbjct: 766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 825
Query: 586 LREGGAQADPEELQQMRQQLENSRI-KLKRYSI 617
+E Q +E++ +++++ N ++ K ++ SI
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
>D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.
Length = 1307
Score = 54.8 bits (126), Expect = 9e-07
Identities = 105/541 (19%), Positives = 231/541 (42%), Gaps = 56/541 (10%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEE--EKASLIEQHKRDE--RAVSDMEDXXXX 154
A K+++ KL++ V+ Q + ++M+ +E EK +E+ + + E+
Sbjct: 716 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 775
Query: 155 XXXXXXXXKDEFNTAAKEHKDLK-ANWDKE-KTDLHKQIADLK--DKLLEANVSNKDQIS 210
K+ + AK++ + A+ +E K +H++ +K ++LLEA +
Sbjct: 776 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 835
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-----------EQCTQLKNQLEKQNF 259
+ +D+ + ++AL+ V++ K + + TS+ EQ +K LE++
Sbjct: 836 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 895
Query: 260 EFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ L++L+ E +S K Q ++ K + ++ E+ L+ E L+
Sbjct: 896 DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL--- 952
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDA 378
+ +L+E+ L+S+ + LQ VQ E K ++ ++ Q S+ H
Sbjct: 953 EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPH----------- 1001
Query: 379 LESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRL 438
E L L + V +++R K + + V + ++ +L
Sbjct: 1002 -EELLKVISEREKEISGLWNELDSLKDAV---EHQRKKNNERQQQVEAVELEAKEVLKKL 1057
Query: 439 QKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ-------LEKSLQ 491
++ + + SY + L +EK+ + G G+ V +L ++++ L+ +
Sbjct: 1058 FPKVSVPSNL--SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECE 1115
Query: 492 GYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT 551
Y+ ++A + K S+ E +W+ + + + + + ++++ LER+ +
Sbjct: 1116 KYKSVLAETE-GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSEN 1174
Query: 552 KVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
K + N E ++ + ELE A+ E +RE AQ + E L ++R + +N R K
Sbjct: 1175 KDI---ENLRRE-REHLEMELEKAEMERSTYVTEVRELKAQLN-ETLTKLRTE-QNERQK 1228
Query: 612 L 612
+
Sbjct: 1229 V 1229
Score = 54.8 bits (126), Expect = 9e-07
Identities = 108/517 (20%), Positives = 204/517 (39%), Gaps = 51/517 (9%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
+A++ K+ ++ +++E++ L EE ++ K + +++
Sbjct: 825 EAELLKVANKEKTVQDLKQEIKALKEE--IGNVQLEKAQQLSITSKVQELQNLLKGKEEQ 882
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+ +E + AN K DL ++ LK + E N + S + +EL
Sbjct: 883 MNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQ-FEELEIV 941
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L+ ++E++ L+ L ++ S TQL ++ +N F+ +LK+ Y++ S
Sbjct: 942 LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQAS----- 996
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
++ L ++E EKE++ L SL+DA+ E Q + R + ++ V+LE
Sbjct: 997 -SFPPHEELLKVISEREKEISGLWNELDSLKDAV------EHQRKKNNERQQQVEAVELE 1049
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
E KL S + HG E ++ + G H
Sbjct: 1050 AKEVLKKLFPKVSVPSNLSYGEWLHGFEKKA--KECMAGTSGSEEVKVLEHKLKEADEMH 1107
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
++ KY+ +V E ++ +LQ+ V +E + ++ ++D E
Sbjct: 1108 TLLQLECEKYK------------SVLAETEGILQKLQRS---VEQEENKWKVKVD--ESH 1150
Query: 463 LTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
T+ S L R++ K ++ R H KA VT RE
Sbjct: 1151 KTIKQMQSSFTSSEQELE-RLRSENKDIENLR-REREHLEMELEKAEMERSTYVTEVREL 1208
Query: 523 AEGARRDVTKLRTQR--------DLLTA--SLERIGPQTKVLHLTNNPAAEAQKQISKEL 572
+TKLRT++ DL A SLE I Q+K++ + +S E
Sbjct: 1209 KAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELI--QSKIVKAAGDTTVIENSDVSPET 1266
Query: 573 EAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
E++++E + V+L + Q + LQ + QQL +
Sbjct: 1267 ESSEKE--TMSVSLNQTVTQLQ-QLLQAVNQQLTKEK 1300
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/513 (18%), Positives = 220/513 (42%), Gaps = 45/513 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 369 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 428
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 429 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 488
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 489 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 539
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 540 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 596
Query: 362 SAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKA 417
S A SA L + L + LT EE+ ++
Sbjct: 597 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 654
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA---G 474
++ L + Q + H L+K V + D R + + E++ + EE
Sbjct: 655 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM--EEFKILND 712
Query: 475 SVALLSARVQQLEK--SLQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDV 530
L + VQ+L+ S Q +D++ + K L+++ + + ++
Sbjct: 713 QNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 772
Query: 531 TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK---ELEAAQE--EIKKLKVA 585
+RT+ LT ++ + + + E +K I + ++++ +E E + LKVA
Sbjct: 773 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 832
Query: 586 LREGGAQADPEELQQMRQQLENSRI-KLKRYSI 617
+E Q +E++ +++++ N ++ K ++ SI
Sbjct: 833 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 865
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 54.8 bits (126), Expect = 9e-07
Identities = 112/546 (20%), Positives = 224/546 (41%), Gaps = 47/546 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD 164
Q ++ + +R ++ + +E++ SL + ++A ED
Sbjct: 681 QDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA----EDQHLVEMEDTLNKLQ 736
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLK---DKLLEANVSNKDQISEMKKDMDELLQ 221
E KE + L+A +++ + + LK +KLL+ + K SE K +M +L Q
Sbjct: 737 EAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS-SEGKSEMKKLRQ 795
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCT------QLK-NQLEKQNFEFQQVTSKL-KELEY 273
LE A+ +++ L+ E ++S+A T +LK L++ E QV L KEL+
Sbjct: 796 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 855
Query: 274 ERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEEQVHQ 328
++ + + ++ ++ Q+ + + + E++ L ++ LR+ + + + E+ +
Sbjct: 856 LKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDER 915
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
++A + ++ ++ E SQL R L+ L A
Sbjct: 916 EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKA-NENAS 973
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESLIHRLQKRLLLVT 446
+++ A K+E +K KL+DL + + L+ R T
Sbjct: 974 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT 1033
Query: 447 RE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEKS--LQGYRDLIA 498
E + + + L +K L T L G EE +G + L +Q +K+ Q D +
Sbjct: 1034 SETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQ 1093
Query: 499 AHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQRDLLTASLERIGP 549
+ K +LE + + + E + + ++V +L ++LLT +++
Sbjct: 1094 IMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEE 1153
Query: 550 QTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPEELQQMRQQLENS 608
K + AA Q S++L A QEE KL L R ++L++ R L N
Sbjct: 1154 FRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQ 1209
Query: 609 RIKLKR 614
+++K+
Sbjct: 1210 LLEMKK 1215
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/222 (20%), Positives = 100/222 (45%), Gaps = 22/222 (9%)
Query: 98 DLIAAKAQITKLESRVNH----QHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L + ++T L+ ++ + T+ KE+QIL +E+ A E+ +R++ + +
Sbjct: 824 ELQGRELKLTNLQENLSEVSQVKETLEKELQIL-KEKFAEASEEAVSVQRSMQETVNKLH 882
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-------LEANVSNK 206
+ + D++A + +EK + +Q+ K+KL ++ + N
Sbjct: 883 QKEEQFNMLSSDLEKLRENLADMEAKF-REKDEREEQLIKAKEKLENDIAEIMKMSGDNS 941
Query: 207 DQISEM-------KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
Q+++M ++D++EL L A L+K + T +AEQ Q +K
Sbjct: 942 SQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ--EAAKKHEE 999
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E +++ KL +LE + ++ + + K +R + + + E
Sbjct: 1000 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE 1041
Score = 41.5 bits (93), Expect = 0.009
Identities = 98/470 (20%), Positives = 203/470 (43%), Gaps = 51/470 (10%)
Query: 174 KDLKANWDKEKTDLHK---QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE- 229
+ L A D E+ ++ K + +++ +L A + + E++ MD+L +E A E
Sbjct: 365 EQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREK 424
Query: 230 VEML------KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
VE+L K+++ R E+ + K LE+++ + + +LE+ R K+ +
Sbjct: 425 VELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHAR--IKELE- 481
Query: 284 QSKTAQKRLCNMAELEKEVTRLRA-NERSLRDAICNKLLLE-EQVHQLTSRVEALQPVQL 341
QS +K + + E E TR+ +E+S + L L ++V +L R+E+ +P
Sbjct: 482 QSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG- 540
Query: 342 ELHEAKVKLSSVE--SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ + LS ++ S L+ + R +L++ +
Sbjct: 541 ---DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAR---EETHQKEIKALYTA 594
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDC 458
L++E +LK + + A + +D+ + K++ E+ I Q+ + + S+ + L
Sbjct: 595 TEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM---EELKVSFSKGLGT 651
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
E E + + Q ++LQ +D A AH+K +E+LR ++ +
Sbjct: 652 ETAEFA------ELKTQIEKMRLDYQHEIENLQNQQDSERA----AHAKEMEALRAKLMK 701
Query: 519 WREEAEGARRDV-TKLRTQRDLLTASLERI----------GPQTKVLHLTNNPAAEAQKQ 567
+E E + + +KL D +E + +VL N +
Sbjct: 702 VIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDN 761
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYSI 617
+ +L+A +E++ L ALR+ ++ E++++RQQLE + ++K I
Sbjct: 762 FTSQLKATEEKLLDLD-ALRKASSEGK-SEMKKLRQQLEAAEKQIKHLEI 809
Score = 39.5 bits (88), Expect = 0.035
Identities = 83/482 (17%), Positives = 204/482 (42%), Gaps = 54/482 (11%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-------SEMKKDMDELLQAL 223
+E L+ + +TD ++I LK+ +++ +I ++ K+ + L L
Sbjct: 550 QEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL 609
Query: 224 EGAQSE----VEMLKKELVKQTSRAEQC-TQLKNQLEK----QNFEFQQVTSKLKEL--- 271
E A E + + K +L + +Q +LK K + EF ++ ++++++
Sbjct: 610 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD 669
Query: 272 -EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH--Q 328
++E ++ ++ Q + A + M L ++ ++ + + +AI +KL E H +
Sbjct: 670 YQHEIENLQNQQDSERAAHAK--EMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 727
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQ---LESWMSAARAHGVESAGALRDALESALGX 385
+ + LQ ++++ E +V + Q ++++ S +A E DAL A
Sbjct: 728 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKA--TEEKLLDLDALRKASSE 785
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLV 445
+++ L+ E++ + K + +T + +E + LQ+ L V
Sbjct: 786 GKSEMKKLRQQLEAA---EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEV 842
Query: 446 TRERDSYRQQL--------DCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI 497
++ +++ ++L + E+ ++V +E + + L L+ R+ +
Sbjct: 843 SQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL 902
Query: 498 AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
A D A + + ++ + +E+ E ++ K+ ++ L ++ + L L
Sbjct: 903 A--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN---SSQLTKMNDE---LRLK 954
Query: 558 NNPAAEAQKQISKELEAA---QEEIKKLKVALREG---GAQADPEELQQMRQQLENSRIK 611
E Q +++K E A Q+ I+ + V + A+ EE +++ ++L + K
Sbjct: 955 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1014
Query: 612 LK 613
++
Sbjct: 1015 ME 1016
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 54.8 bits (126), Expect = 9e-07
Identities = 117/551 (21%), Positives = 237/551 (43%), Gaps = 62/551 (11%)
Query: 91 ETKRLKIDLIAAKAQ-ITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
ETKR + + K + I +L SR+ T +E++ E+ + + E+ E+A+S +
Sbjct: 31 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL---EKALSTAQ 87
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ T K ++ + + +E + + +++ D+ K S+++QI
Sbjct: 88 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK------SSEEQI 141
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF-------- 261
++++K L E A+ E E+ KK QT E Q+K LEK E+
Sbjct: 142 AKLQK-----LHEKELARKEQELTKK---LQTREREFQEQMKVALEKSQSEYLKISQEKE 193
Query: 262 QQVTSKLKELEYER--------DSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSL 312
QQ + L+ELE ++ + +D Q +++T + R+ + + LEK + + + L
Sbjct: 194 QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 253
Query: 313 R---DAICNKLLLE--EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAH 367
+A NK +E V + + +E+L+ Q L K+++ + Q E +
Sbjct: 254 AVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE 313
Query: 368 GVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E L+D E +++ E KA KL + +V
Sbjct: 314 -QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 372
Query: 428 RKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
K+Q + + L+ ++ +++ ++QQ+D KE V++ E A L ++ QL
Sbjct: 373 LKDQTDKMKQELEAKM---DEQKNHHQQQVDSIIKEHEVSIQRTEKA-----LKDQINQL 424
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA--------EGARRDVTKLRTQRD 538
E L+ + H H + + R+E + A + A + TK +
Sbjct: 425 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK-AYEEQ 483
Query: 539 LLTASLERIGPQTKVLHLTNNPA-AEAQKQ-ISKELEAAQEEIKKLKVALREGGAQADPE 596
L + + +T+ + LT A EAQK+ + EL+A + +++ L L + ++ + +
Sbjct: 484 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME-Q 542
Query: 597 ELQQMRQQLEN 607
+++ + Q E+
Sbjct: 543 KVKSLTQVYES 553
Score = 38.7 bits (86), Expect = 0.060
Identities = 54/257 (21%), Positives = 110/257 (42%), Gaps = 28/257 (10%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L+ +L K Q K++ + + +K +++ S+I++H E ++ E
Sbjct: 365 KLEEELSVLKDQTDKMKQELEAKMDEQKNHH---QQQVDSIIKEH---EVSIQRTEKALK 418
Query: 154 XXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
E + KEH+ +L+A+ + + +L + A L D + +Q
Sbjct: 419 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQT 477
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLK----------NQLEKQN 258
++ + +L Q L ++E +L K++ + + + + CT+L QLEKQN
Sbjct: 478 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 537
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
E +Q L ++ YE + Q +T Q + E E + ++R ++ + +
Sbjct: 538 SEMEQKVKSLTQV-YESKLEDGNKEQEQTKQ----ILVEKENMILQMREGQKKEIEILTQ 592
Query: 319 KL-LLEEQVHQLTSRVE 334
KL E+ +H L E
Sbjct: 593 KLSAKEDSIHILNEEYE 609
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 54.4 bits (125), Expect = 1e-06
Identities = 88/455 (19%), Positives = 183/455 (40%), Gaps = 27/455 (5%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQ----ALEGA 226
K+H + + +L+K++ +DKL+ +V+ K+ + ++ K+M + ++ E A
Sbjct: 245 KQHMNTIKQLESRIEELNKEVKASRDKLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEA 304
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ----NFEFQQVTSKLKELEYERDSYKDWQ 282
+ E E + + V+ + + K LEK+ N E ++ T+K+K+L E+
Sbjct: 305 RQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLY 364
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ RL + E++K + ++ ++ A NKL E H+ T + L+ +
Sbjct: 365 ETKEGETTRL--IREIDKLKEDINSHVIKVKWA-QNKLKAEMDSHKETK--DKLKETTTK 419
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
L +AK + + + + + + L L G
Sbjct: 420 LTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHA 479
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLLLVTRERDSYRQQLDC 458
+E+ LK + +L L T K E R L K ++ R++ + LD
Sbjct: 480 KIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDK 539
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ + + G + L V+ L + DL D K L R
Sbjct: 540 VKTADQLQEQLQRGKQEIENLKEEVESLNSLI---NDL--QKDIEGSRKRESELLLFTER 594
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+ + + L++Q D ++ S ++ Q + + TN + ++ KE E +EE
Sbjct: 595 LTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTN---INLESRLLKEEELRKEE 651
Query: 579 IKKL--KVALREGGAQADPEELQQMRQQLENSRIK 611
++ L ++A R+ +A ++++++ +L R K
Sbjct: 652 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686
Score = 44.0 bits (99), Expect = 0.002
Identities = 90/453 (19%), Positives = 168/453 (37%), Gaps = 42/453 (9%)
Query: 194 LKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
++DK L+ K I E KK + + + E LKK + QL+++
Sbjct: 198 VQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESR 257
Query: 254 LEKQNFEFQQVTSKLKELEYE-----RDSYKDWQTQSKTAQKRLCNMAELEKE--VTRLR 306
+E+ N E + KL + + +K+ + + A K+ C A EKE V +
Sbjct: 258 IEELNKEVKASRDKLIAQDVTAKNAVQQLHKEMAQRMEQANKK-CEEARQEKEAMVMKYV 316
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
E+ D K LE+++ +E +L + K +L QL
Sbjct: 317 RGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRL----HQLYETKEGETT 372
Query: 367 HGVESAGALRDALES-------ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG 419
+ L++ + S A T ++ K E D+
Sbjct: 373 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRK 432
Query: 420 KLND-LTTVRKNQESLIHRLQKRLLLVTRERDSYRQ----QLDCYE---KEL-TVTLCGE 470
D + T ++++E + L +L + E + Q QL+ + KEL + +
Sbjct: 433 NCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK 492
Query: 471 EGAGSVALLSARVQQL-------EKSLQGYRDLIAAHDPHAHS-----KALESLRNEVTR 518
EG + L +V+ L E L Y+++I + K + L+ ++ R
Sbjct: 493 EGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQR 552
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
++E E + +V L + + L +E + L L Q+ E + Q +
Sbjct: 553 GKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQ 612
Query: 579 IKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
KV+ E Q+ E+++Q LE+ +K
Sbjct: 613 FD--KVSCSESQLQSQCEQMKQTNINLESRLLK 643
>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 54.4 bits (125), Expect = 1e-06
Identities = 88/423 (20%), Positives = 173/423 (40%), Gaps = 25/423 (5%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ E+++ +DE ++ + + L+++L ++T E+C++L+ LE++ E QQ +
Sbjct: 367 KVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKT---EECSRLQELLERRKGEAQQSNKE 423
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L+ ++ D +D + +T L N +L+ A E L+D + + LLEE +
Sbjct: 424 LQNMKRLLDQGEDLRHGLETQVMELQN--KLKHVQGPEPAKEVLLKDLLETRELLEEVLE 481
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
E L+ + EL K L + + + R LR +++ A
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 541
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
L E+ E + TG + +KN+E L ++ LL +
Sbjct: 542 VLEAERQKMSALVRGLQRELE----ETSEETGHWQSM--FQKNKEDL-RATKQELLQLRM 594
Query: 448 ERDSYRQQL----DCYEKELTVTLCGEEGAGSVALLS---ARVQQLEKSLQGYR---DLI 497
E++ ++L + ++EL V +L R Q+ K LQ R ++
Sbjct: 595 EKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVA 654
Query: 498 AAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL 556
H K L LR E R RE E + + T + ++D AS ++ + + L
Sbjct: 655 GRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVL 714
Query: 557 TNNPAA--EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AA ++ +E + + I L+ L+E D E + R + + R++ ++
Sbjct: 715 GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEK 774
Query: 615 YSI 617
+
Sbjct: 775 QQL 777
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/452 (20%), Positives = 183/452 (40%), Gaps = 38/452 (8%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTS 242
E +K++ ++K +LL+ + + ++ L+ ++G + E+L K+L++
Sbjct: 416 EAQQSNKELQNMK-RLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRE 474
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
E+ + K ++E+Q ++ + LK E + +D + + Q +++
Sbjct: 475 LLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQ--------YQRDT 526
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+LR RS++DA + +LE + ++++ V L Q EL E + +S +
Sbjct: 527 EQLR---RSMQDATQDHAVLEAERQKMSALVRGL---QRELEETSEETGHWQSMFQKNKE 580
Query: 363 AARAHGVE--SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
RA E ++ +E LG T +V LK E + +
Sbjct: 581 DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEE 640
Query: 421 LNDLTTVRKNQE-SLIHR---LQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV 476
L +L R++QE + HR L+K+L ++ E D R +L+ +L TL
Sbjct: 641 LKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGR-ELEEQNLQLQKTLQQLRQDCEE 699
Query: 477 ALLSARVQQLEKSLQGYRDLI-------AAHDPHAHSKALESLRNEVTRWREEAEGARRD 529
A + V + E ++ G R + + + L ++ R +G
Sbjct: 700 ASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAV 759
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ-------EEIKKL 582
+LR + L A +++ A A++ + LE AQ +E + L
Sbjct: 760 EARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTL 819
Query: 583 KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AL E G Q E L++ + +LE + L R
Sbjct: 820 NRALEEEGKQR--EVLRRGKAELEEQKRLLDR 849
Score = 44.0 bits (99), Expect = 0.002
Identities = 88/435 (20%), Positives = 177/435 (40%), Gaps = 32/435 (7%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK+ + K+++ +L E + E+ + L ++ +A Q+E E +
Sbjct: 578 NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRT 637
Query: 265 TSKLKELEYERDS------YKDWQTQSKTAQKRL--CNMAELEKEVTRLRANERSLR--- 313
+LKEL+ ER S ++D + + + A R+ ELE++ +L+ + LR
Sbjct: 638 QEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDC 697
Query: 314 -DAICNKLLLEEQVHQLTSR---VE-ALQPVQLELHEAKVKLSSVESQLESWMSAARAHG 368
+A K++ E + L R VE L+ Q E E + ++ +E QL+ + G
Sbjct: 698 EEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKE--TRGLVDG 755
Query: 369 VESAGA-LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E+ A LRD L+ L L+ ++A L L
Sbjct: 756 GEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQE 815
Query: 428 RKNQESLIHRLQKRLLLVTR---ERDSYRQQLDCYEKELTVTL--CGEEGAGSVALLSAR 482
++ + K+ ++ R E + ++ LD L L GE+ ++ L A+
Sbjct: 816 QQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQ 875
Query: 483 VQQL-EKSLQGYRDLIA-----AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ 536
++ EK+ + D A + S L L++E+ R R+ + ++ + R
Sbjct: 876 LEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLD 935
Query: 537 RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEI--KKLKVALREGGAQAD 594
++LL L+ + + + + + A K + +++ + E+ +K V L
Sbjct: 936 KELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG 995
Query: 595 PEELQQMRQQLENSR 609
+++ Q+R +L R
Sbjct: 996 RDQVDQLRTELMQER 1010
Score = 41.1 bits (92), Expect = 0.011
Identities = 37/164 (22%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
Query: 197 KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
K LE VS + ++ E K ++ L + + +V+ L+ EL+++ S + K LE
Sbjct: 965 KGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLE 1024
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+QN + + + + + S ++Q++ Q+RL AE E+E T L++ R L
Sbjct: 1025 RQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERL--QAE-EREKTVLQSTNRKLERK 1081
Query: 316 ICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ + +E++ + + + L L + K ++ E ++E
Sbjct: 1082 VKELSIQIEDERQHVNDQKDQL---SLRVKALKRQVDEAEEEIE 1122
Score = 36.3 bits (80), Expect = 0.32
Identities = 44/210 (20%), Positives = 94/210 (44%), Gaps = 9/210 (4%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE---LLQALEGA 226
A++ K L+ + +T+L ++ + + L + +DQ+ +++ ++ + Q LE
Sbjct: 961 ARQLKGLEEKVSRLETELDEE-KNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECD 1019
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +E K+L + + +E + L + + Q + +L+ E E+ + + +
Sbjct: 1020 KISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLE 1079
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELH 344
K L E E++ + ++ SLR + + EE++ +L + Q E H
Sbjct: 1080 RKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQH 1139
Query: 345 EAKVKLSSVESQLE--SWMSAARAHGVESA 372
E +L + LE SW A+R+ ESA
Sbjct: 1140 EVNEQLQARIKSLEKDSWRKASRS-AAESA 1168
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 54.4 bits (125), Expect = 1e-06
Identities = 116/522 (22%), Positives = 201/522 (38%), Gaps = 34/522 (6%)
Query: 126 LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDK 182
L + K L + K + D E+ +DE K+ DLK A +K
Sbjct: 956 LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE---VEMLKKELVK 239
EK ++ +L +++ + S E K + QAL Q+E V L K ++
Sbjct: 1016 EKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR 1075
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
+ E Q +K + ++ KL+ +L+ ++S D Q K + +
Sbjct: 1076 LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD-AAQDKQQLEEKLKKKDS 1134
Query: 299 EKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQP----VQLELHEAKVKLSS 352
E LR + L A K + L+ + +L +EA + V+ + EA +L
Sbjct: 1135 ELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEE 1194
Query: 353 VESQLE--SWMSAARAHGVE----SAGALRDAL-ESALGXXXXXXXXXXXXXXXXXHLTE 405
+ +LE SA + G G LR L E+AL L E
Sbjct: 1195 LSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGE 1254
Query: 406 EVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
+V +L+ R K + ++L + + + L + + +Y QL E ++ V
Sbjct: 1255 QVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLS--EAKIKV 1312
Query: 466 TLCGEEGAGSV---ALLSARVQQLEKSLQGYRDLIA--AHDPHAHSKALESLRNEVTRWR 520
+ A + L +L + L+ LI+ + +++LE LR ++
Sbjct: 1313 EELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEES 1372
Query: 521 EEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ-- 576
+ V LR DLL E Q ++ L + AE + SK E +A Q
Sbjct: 1373 KAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRT 1432
Query: 577 EEIK--KLKVALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
EE++ K K+ALR A+ E LE ++++L+ S
Sbjct: 1433 EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTES 1474
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/296 (23%), Positives = 132/296 (44%), Gaps = 21/296 (7%)
Query: 91 ETKRLKIDLIAAKAQIT-KLESRVNHQHTIRKEMQILFEEEKASL-IEQHKRDE--RAVS 146
+T R++++L KA++ KL + +R+ Q E +ASL E R+E R
Sbjct: 1606 KTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKK 1665
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
ME + A + ++A +E+ ++ L +L E + +
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEE-QRLAAELHEQAQALE 1724
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA----EQCTQLKNQLEKQNFEFQ 262
+ S + +++EL ALE + + ++EL++ T R Q T L NQ +K +
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 1784
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLRANERSLRDAICNKLL 321
Q++ +++E ER ++ + ++K A MA EL+KE ER K
Sbjct: 1785 QLSGEVEEAAQER---REAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-------KKT 1834
Query: 322 LEEQVHQLTSRVEALQPVQLELHEAKV-KLSSVESQLESWMSAARAHGVESAGALR 376
LE+ V +L +R+E + L + +V KL + +LE+ + A + E+ +R
Sbjct: 1835 LEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVR 1890
Score = 50.0 bits (114), Expect = 2e-05
Identities = 85/469 (18%), Positives = 182/469 (38%), Gaps = 31/469 (6%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+++ ++ +E++ E E+A+ K+ A ++E+ +
Sbjct: 1152 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1211
Query: 168 TAAKEHKDL-KANWDKEKTDLHKQ--IADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
K +L + + E+ L + +A L+ K E +Q+ +++ +L +
Sbjct: 1212 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 1271
Query: 225 GAQSEVEMLK---KELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
+ EV+ L + L + + AE+ C ++QL + + +++ +L + +R +
Sbjct: 1272 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 1331
Query: 281 WQTQ-SKTAQKRLCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+ S+ +++ C +++L + L R L + K L V L +
Sbjct: 1332 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDL 1391
Query: 336 LQPVQLELHEAKVKL----SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
L+ E EA+ +L S +++ W S A ++ L +A +
Sbjct: 1392 LREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEE 1451
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
L + L+ E + T +L T+ + L++ L R+ +
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1511
Query: 452 YRQQLDCYEKE---LTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDLIAA---- 499
+++L+ ++E L L EE ++ L + L++ + D ++
Sbjct: 1512 MQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKS 1571
Query: 500 -HDPHAHSKALESLRNEVTRWREEAEGA-RRDVTK-LRTQRDLLTASLE 545
+ KALE ++E+ EEAEGA + TK LR Q +L E
Sbjct: 1572 IQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1620
Score = 35.9 bits (79), Expect = 0.43
Identities = 65/325 (20%), Positives = 129/325 (39%), Gaps = 20/325 (6%)
Query: 290 KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQL-TSRVEALQPVQLELHEAKV 348
K L A+ E+E+ LRA R LR A+ +++ + S + + L+L +
Sbjct: 886 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 945
Query: 349 KLSSVESQLESWM-SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEV 407
L+ E + + S + G L + LE L +++
Sbjct: 946 NLADAEERCHLLIKSKVQLEG--KVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 408 ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTL 467
LK KA + KN + L + + +T+E+ + + + +++ L
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQ---EAHQQALGDLQ 1060
Query: 468 CGEEGAGSVALLSARVQQ----LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
E+ ++ R++Q LE SL+ + L + +A L ++ +E
Sbjct: 1061 AEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTE-----RAKRKLEGDLKLTQESV 1115
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
A +D +L + + L ++ + + L A+ QK+I KEL+A EE+++
Sbjct: 1116 ADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLL---GAQMQKKI-KELQARAEELEEEL 1171
Query: 584 VALREGGAQADPEELQQMRQQLENS 608
A R A+ + + + R+ E S
Sbjct: 1172 EAERAARARVEKQRAEAARELEELS 1196
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 54.4 bits (125), Expect = 1e-06
Identities = 116/522 (22%), Positives = 201/522 (38%), Gaps = 34/522 (6%)
Query: 126 LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDK 182
L + K L + K + D E+ +DE K+ DLK A +K
Sbjct: 956 LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE---VEMLKKELVK 239
EK ++ +L +++ + S E K + QAL Q+E V L K ++
Sbjct: 1016 EKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR 1075
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
+ E Q +K + ++ KL+ +L+ ++S D Q K + +
Sbjct: 1076 LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD-AAQDKQQLEEKLKKKDS 1134
Query: 299 EKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQP----VQLELHEAKVKLSS 352
E LR + L A K + L+ + +L +EA + V+ + EA +L
Sbjct: 1135 ELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEE 1194
Query: 353 VESQLE--SWMSAARAHGVE----SAGALRDAL-ESALGXXXXXXXXXXXXXXXXXHLTE 405
+ +LE SA + G G LR L E+AL L E
Sbjct: 1195 LSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGE 1254
Query: 406 EVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
+V +L+ R K + ++L + + + L + + +Y QL E ++ V
Sbjct: 1255 QVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLS--EAKIKV 1312
Query: 466 TLCGEEGAGSV---ALLSARVQQLEKSLQGYRDLIA--AHDPHAHSKALESLRNEVTRWR 520
+ A + L +L + L+ LI+ + +++LE LR ++
Sbjct: 1313 EELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEES 1372
Query: 521 EEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ-- 576
+ V LR DLL E Q ++ L + AE + SK E +A Q
Sbjct: 1373 KAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRT 1432
Query: 577 EEIK--KLKVALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
EE++ K K+ALR A+ E LE ++++L+ S
Sbjct: 1433 EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTES 1474
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/296 (23%), Positives = 132/296 (44%), Gaps = 21/296 (7%)
Query: 91 ETKRLKIDLIAAKAQIT-KLESRVNHQHTIRKEMQILFEEEKASL-IEQHKRDE--RAVS 146
+T R++++L KA++ KL + +R+ Q E +ASL E R+E R
Sbjct: 1606 KTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKK 1665
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
ME + A + ++A +E+ ++ L +L E + +
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEE-QRLAAELHEQAQALE 1724
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA----EQCTQLKNQLEKQNFEFQ 262
+ S + +++EL ALE + + ++EL++ T R Q T L NQ +K +
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 1784
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLRANERSLRDAICNKLL 321
Q++ +++E ER ++ + ++K A MA EL+KE ER K
Sbjct: 1785 QLSGEVEEAAQER---REAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-------KKT 1834
Query: 322 LEEQVHQLTSRVEALQPVQLELHEAKV-KLSSVESQLESWMSAARAHGVESAGALR 376
LE+ V +L +R+E + L + +V KL + +LE+ + A + E+ +R
Sbjct: 1835 LEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVR 1890
Score = 50.0 bits (114), Expect = 2e-05
Identities = 85/469 (18%), Positives = 182/469 (38%), Gaps = 31/469 (6%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+++ ++ +E++ E E+A+ K+ A ++E+ +
Sbjct: 1152 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1211
Query: 168 TAAKEHKDL-KANWDKEKTDLHKQ--IADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
K +L + + E+ L + +A L+ K E +Q+ +++ +L +
Sbjct: 1212 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 1271
Query: 225 GAQSEVEMLK---KELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
+ EV+ L + L + + AE+ C ++QL + + +++ +L + +R +
Sbjct: 1272 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 1331
Query: 281 WQTQ-SKTAQKRLCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+ S+ +++ C +++L + L R L + K L V L +
Sbjct: 1332 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDL 1391
Query: 336 LQPVQLELHEAKVKL----SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
L+ E EA+ +L S +++ W S A ++ L +A +
Sbjct: 1392 LREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEE 1451
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
L + L+ E + T +L T+ + L++ L R+ +
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1511
Query: 452 YRQQLDCYEKE---LTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDLIAA---- 499
+++L+ ++E L L EE ++ L + L++ + D ++
Sbjct: 1512 MQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKS 1571
Query: 500 -HDPHAHSKALESLRNEVTRWREEAEGA-RRDVTK-LRTQRDLLTASLE 545
+ KALE ++E+ EEAEGA + TK LR Q +L E
Sbjct: 1572 IQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1620
Score = 35.9 bits (79), Expect = 0.43
Identities = 65/325 (20%), Positives = 129/325 (39%), Gaps = 20/325 (6%)
Query: 290 KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQL-TSRVEALQPVQLELHEAKV 348
K L A+ E+E+ LRA R LR A+ +++ + S + + L+L +
Sbjct: 886 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 945
Query: 349 KLSSVESQLESWM-SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEV 407
L+ E + + S + G L + LE L +++
Sbjct: 946 NLADAEERCHLLIKSKVQLEG--KVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 408 ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTL 467
LK KA + KN + L + + +T+E+ + + + +++ L
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQ---EAHQQALGDLQ 1060
Query: 468 CGEEGAGSVALLSARVQQ----LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
E+ ++ R++Q LE SL+ + L + +A L ++ +E
Sbjct: 1061 AEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTE-----RAKRKLEGDLKLTQESV 1115
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
A +D +L + + L ++ + + L A+ QK+I KEL+A EE+++
Sbjct: 1116 ADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLL---GAQMQKKI-KELQARAEELEEEL 1171
Query: 584 VALREGGAQADPEELQQMRQQLENS 608
A R A+ + + + R+ E S
Sbjct: 1172 EAERAARARVEKQRAEAARELEELS 1196
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 54.4 bits (125), Expect = 1e-06
Identities = 88/455 (19%), Positives = 183/455 (40%), Gaps = 27/455 (5%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQ----ALEGA 226
K+H + + +L+K++ +DKL+ +V+ K+ + ++ K+M + ++ E A
Sbjct: 62 KQHMNTIKQLESRIEELNKEVKASRDKLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEA 121
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ----NFEFQQVTSKLKELEYERDSYKDWQ 282
+ E E + + V+ + + K LEK+ N E ++ T+K+K+L E+
Sbjct: 122 RQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLY 181
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ RL + E++K + ++ ++ A NKL E H+ T + L+ +
Sbjct: 182 ETKEGETTRL--IREIDKLKEDINSHVIKVKWA-QNKLKAEMDSHKETK--DKLKETTTK 236
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
L +AK + + + + + + L L G
Sbjct: 237 LTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHA 296
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLLLVTRERDSYRQQLDC 458
+E+ LK + +L L T K E R L K ++ R++ + LD
Sbjct: 297 KIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDK 356
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ + + G + L V+ L + DL D K L R
Sbjct: 357 VKTADQLQEQLQRGKQEIENLKEEVESLNSLI---NDL--QKDIEGSRKRESELLLFTER 411
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+ + + L++Q D ++ S ++ Q + + TN + ++ KE E +EE
Sbjct: 412 LTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTN---INLESRLLKEEELRKEE 468
Query: 579 IKKL--KVALREGGAQADPEELQQMRQQLENSRIK 611
++ L ++A R+ +A ++++++ +L R K
Sbjct: 469 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 503
Score = 44.0 bits (99), Expect = 0.002
Identities = 90/453 (19%), Positives = 168/453 (37%), Gaps = 42/453 (9%)
Query: 194 LKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
++DK L+ K I E KK + + + E LKK + QL+++
Sbjct: 15 VQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESR 74
Query: 254 LEKQNFEFQQVTSKLKELEYE-----RDSYKDWQTQSKTAQKRLCNMAELEKE--VTRLR 306
+E+ N E + KL + + +K+ + + A K+ C A EKE V +
Sbjct: 75 IEELNKEVKASRDKLIAQDVTAKNAVQQLHKEMAQRMEQANKK-CEEARQEKEAMVMKYV 133
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
E+ D K LE+++ +E +L + K +L QL
Sbjct: 134 RGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRL----HQLYETKEGETT 189
Query: 367 HGVESAGALRDALES-------ALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG 419
+ L++ + S A T ++ K E D+
Sbjct: 190 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRK 249
Query: 420 KLND-LTTVRKNQESLIHRLQKRLLLVTRERDSYRQ----QLDCYE---KEL-TVTLCGE 470
D + T ++++E + L +L + E + Q QL+ + KEL + +
Sbjct: 250 NCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK 309
Query: 471 EGAGSVALLSARVQQL-------EKSLQGYRDLIAAHDPHAHS-----KALESLRNEVTR 518
EG + L +V+ L E L Y+++I + K + L+ ++ R
Sbjct: 310 EGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQR 369
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
++E E + +V L + + L +E + L L Q+ E + Q +
Sbjct: 370 GKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQ 429
Query: 579 IKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
KV+ E Q+ E+++Q LE+ +K
Sbjct: 430 FD--KVSCSESQLQSQCEQMKQTNINLESRLLK 460
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 54.4 bits (125), Expect = 1e-06
Identities = 88/423 (20%), Positives = 173/423 (40%), Gaps = 25/423 (5%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ E+++ +DE ++ + + L+++L ++T E+C++L+ LE++ E QQ +
Sbjct: 367 KVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKT---EECSRLQELLERRKGEAQQSNKE 423
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L+ ++ D +D + +T L N +L+ A E L+D + + LLEE +
Sbjct: 424 LQNMKRLLDQGEDLRHGLETQVMELQN--KLKHVQGPEPAKEVLLKDLLETRELLEEVLE 481
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
E L+ + EL K L + + + R LR +++ A
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 541
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
L E+ E + TG + +KN+E L ++ LL +
Sbjct: 542 VLEAERQKMSALVRGLQRELE----ETSEETGHWQSM--FQKNKEDL-RATKQELLQLRM 594
Query: 448 ERDSYRQQL----DCYEKELTVTLCGEEGAGSVALLS---ARVQQLEKSLQGYR---DLI 497
E++ ++L + ++EL V +L R Q+ K LQ R ++
Sbjct: 595 EKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVA 654
Query: 498 AAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL 556
H K L LR E R RE E + + T + ++D AS ++ + + L
Sbjct: 655 GRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVL 714
Query: 557 TNNPAA--EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AA ++ +E + + I L+ L+E D E + R + + R++ ++
Sbjct: 715 GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEK 774
Query: 615 YSI 617
+
Sbjct: 775 QQL 777
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/452 (20%), Positives = 183/452 (40%), Gaps = 38/452 (8%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTS 242
E +K++ ++K +LL+ + + ++ L+ ++G + E+L K+L++
Sbjct: 416 EAQQSNKELQNMK-RLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRE 474
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
E+ + K ++E+Q ++ + LK E + +D + + Q +++
Sbjct: 475 LLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQ--------YQRDT 526
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+LR RS++DA + +LE + ++++ V L Q EL E + +S +
Sbjct: 527 EQLR---RSMQDATQDHAVLEAERQKMSALVRGL---QRELEETSEETGHWQSMFQKNKE 580
Query: 363 AARAHGVE--SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
RA E ++ +E LG T +V LK E + +
Sbjct: 581 DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEE 640
Query: 421 LNDLTTVRKNQE-SLIHR---LQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV 476
L +L R++QE + HR L+K+L ++ E D R +L+ +L TL
Sbjct: 641 LKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGR-ELEEQNLQLQKTLQQLRQDCEE 699
Query: 477 ALLSARVQQLEKSLQGYRDLI-------AAHDPHAHSKALESLRNEVTRWREEAEGARRD 529
A + V + E ++ G R + + + L ++ R +G
Sbjct: 700 ASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAV 759
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ-------EEIKKL 582
+LR + L A +++ A A++ + LE AQ +E + L
Sbjct: 760 EARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTL 819
Query: 583 KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AL E G Q E L++ + +LE + L R
Sbjct: 820 NRALEEEGKQR--EVLRRGKAELEEQKRLLDR 849
Score = 44.0 bits (99), Expect = 0.002
Identities = 88/435 (20%), Positives = 177/435 (40%), Gaps = 32/435 (7%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK+ + K+++ +L E + E+ + L ++ +A Q+E E +
Sbjct: 578 NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRT 637
Query: 265 TSKLKELEYERDS------YKDWQTQSKTAQKRL--CNMAELEKEVTRLRANERSLR--- 313
+LKEL+ ER S ++D + + + A R+ ELE++ +L+ + LR
Sbjct: 638 QEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDC 697
Query: 314 -DAICNKLLLEEQVHQLTSR---VE-ALQPVQLELHEAKVKLSSVESQLESWMSAARAHG 368
+A K++ E + L R VE L+ Q E E + ++ +E QL+ + G
Sbjct: 698 EEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKE--TRGLVDG 755
Query: 369 VESAGA-LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E+ A LRD L+ L L+ ++A L L
Sbjct: 756 GEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQE 815
Query: 428 RKNQESLIHRLQKRLLLVTR---ERDSYRQQLDCYEKELTVTL--CGEEGAGSVALLSAR 482
++ + K+ ++ R E + ++ LD L L GE+ ++ L A+
Sbjct: 816 QQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQ 875
Query: 483 VQQL-EKSLQGYRDLIA-----AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ 536
++ EK+ + D A + S L L++E+ R R+ + ++ + R
Sbjct: 876 LEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLD 935
Query: 537 RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEI--KKLKVALREGGAQAD 594
++LL L+ + + + + + A K + +++ + E+ +K V L
Sbjct: 936 KELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG 995
Query: 595 PEELQQMRQQLENSR 609
+++ Q+R +L R
Sbjct: 996 RDQVDQLRTELMQER 1010
Score = 41.1 bits (92), Expect = 0.011
Identities = 37/164 (22%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
Query: 197 KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
K LE VS + ++ E K ++ L + + +V+ L+ EL+++ S + K LE
Sbjct: 965 KGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLE 1024
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+QN + + + + + S ++Q++ Q+RL AE E+E T L++ R L
Sbjct: 1025 RQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERL--QAE-EREKTVLQSTNRKLERK 1081
Query: 316 ICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ + +E++ + + + L L + K ++ E ++E
Sbjct: 1082 VKELSIQIEDERQHVNDQKDQL---SLRVKALKRQVDEAEEEIE 1122
Score = 36.3 bits (80), Expect = 0.32
Identities = 44/210 (20%), Positives = 94/210 (44%), Gaps = 9/210 (4%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE---LLQALEGA 226
A++ K L+ + +T+L ++ + + L + +DQ+ +++ ++ + Q LE
Sbjct: 961 ARQLKGLEEKVSRLETELDEE-KNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECD 1019
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +E K+L + + +E + L + + Q + +L+ E E+ + + +
Sbjct: 1020 KISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLE 1079
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELH 344
K L E E++ + ++ SLR + + EE++ +L + Q E H
Sbjct: 1080 RKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQH 1139
Query: 345 EAKVKLSSVESQLE--SWMSAARAHGVESA 372
E +L + LE SW A+R+ ESA
Sbjct: 1140 EVNEQLQARIKSLEKDSWRKASRS-AAESA 1168
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 54.4 bits (125), Expect = 1e-06
Identities = 88/423 (20%), Positives = 173/423 (40%), Gaps = 25/423 (5%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ E+++ +DE ++ + + L+++L ++T E+C++L+ LE++ E QQ +
Sbjct: 372 KVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKT---EECSRLQELLERRKGEAQQSNKE 428
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L+ ++ D +D + +T L N +L+ A E L+D + + LLEE +
Sbjct: 429 LQNMKRLLDQGEDLRHGLETQVMELQN--KLKHVQGPEPAKEVLLKDLLETRELLEEVLE 486
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
E L+ + EL K L + + + R LR +++ A
Sbjct: 487 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 546
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
L E+ E + TG + +KN+E L ++ LL +
Sbjct: 547 VLEAERQKMSALVRGLQRELE----ETSEETGHWQSM--FQKNKEDL-RATKQELLQLRM 599
Query: 448 ERDSYRQQL----DCYEKELTVTLCGEEGAGSVALLS---ARVQQLEKSLQGYR---DLI 497
E++ ++L + ++EL V +L R Q+ K LQ R ++
Sbjct: 600 EKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVA 659
Query: 498 AAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL 556
H K L LR E R RE E + + T + ++D AS ++ + + L
Sbjct: 660 GRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVL 719
Query: 557 TNNPAA--EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AA ++ +E + + I L+ L+E D E + R + + R++ ++
Sbjct: 720 GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEK 779
Query: 615 YSI 617
+
Sbjct: 780 QQL 782
Score = 50.8 bits (116), Expect = 1e-05
Identities = 94/452 (20%), Positives = 183/452 (40%), Gaps = 38/452 (8%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTS 242
E +K++ ++K +LL+ + + ++ L+ ++G + E+L K+L++
Sbjct: 421 EAQQSNKELQNMK-RLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRE 479
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
E+ + K ++E+Q ++ + LK E + +D + + Q +++
Sbjct: 480 LLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQ--------YQRDT 531
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
+LR RS++DA + +LE + ++++ V L Q EL E + +S +
Sbjct: 532 EQLR---RSMQDATQDHAVLEAERQKMSALVRGL---QRELEETSEETGHWQSMFQKNKE 585
Query: 363 AARAHGVE--SAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
RA E ++ +E LG T +V LK E + +
Sbjct: 586 DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEE 645
Query: 421 LNDLTTVRKNQE-SLIHR---LQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV 476
L +L R++QE + HR L+K+L ++ E D R +L+ +L TL
Sbjct: 646 LKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGR-ELEEQNLQLQKTLQQLRQDCEE 704
Query: 477 ALLSARVQQLEKSLQGYRDLI-------AAHDPHAHSKALESLRNEVTRWREEAEGARRD 529
A + V + E ++ G R + + + L ++ R +G
Sbjct: 705 ASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAV 764
Query: 530 VTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ-------EEIKKL 582
+LR + L A +++ A A++ + LE AQ +E + L
Sbjct: 765 EARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTL 824
Query: 583 KVALREGGAQADPEELQQMRQQLENSRIKLKR 614
AL E G Q E L++ + +LE + L R
Sbjct: 825 NRALEEEGKQR--EVLRRGKAELEEQKRLLDR 854
Score = 44.0 bits (99), Expect = 0.002
Identities = 88/435 (20%), Positives = 177/435 (40%), Gaps = 32/435 (7%)
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK+ + K+++ +L E + E+ + L ++ +A Q+E E +
Sbjct: 583 NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRT 642
Query: 265 TSKLKELEYERDS------YKDWQTQSKTAQKRL--CNMAELEKEVTRLRANERSLR--- 313
+LKEL+ ER S ++D + + + A R+ ELE++ +L+ + LR
Sbjct: 643 QEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDC 702
Query: 314 -DAICNKLLLEEQVHQLTSR---VE-ALQPVQLELHEAKVKLSSVESQLESWMSAARAHG 368
+A K++ E + L R VE L+ Q E E + ++ +E QL+ + G
Sbjct: 703 EEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKE--TRGLVDG 760
Query: 369 VESAGA-LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E+ A LRD L+ L L+ ++A L L
Sbjct: 761 GEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQE 820
Query: 428 RKNQESLIHRLQKRLLLVTR---ERDSYRQQLDCYEKELTVTL--CGEEGAGSVALLSAR 482
++ + K+ ++ R E + ++ LD L L GE+ ++ L A+
Sbjct: 821 QQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQ 880
Query: 483 VQQL-EKSLQGYRDLIA-----AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ 536
++ EK+ + D A + S L L++E+ R R+ + ++ + R
Sbjct: 881 LEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLD 940
Query: 537 RDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEI--KKLKVALREGGAQAD 594
++LL L+ + + + + + A K + +++ + E+ +K V L
Sbjct: 941 KELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG 1000
Query: 595 PEELQQMRQQLENSR 609
+++ Q+R +L R
Sbjct: 1001 RDQVDQLRTELMQER 1015
Score = 41.1 bits (92), Expect = 0.011
Identities = 37/164 (22%), Positives = 78/164 (47%), Gaps = 8/164 (4%)
Query: 197 KLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
K LE VS + ++ E K ++ L + + +V+ L+ EL+++ S + K LE
Sbjct: 970 KGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLE 1029
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+QN + + + + + S ++Q++ Q+RL AE E+E T L++ R L
Sbjct: 1030 RQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERL--QAE-EREKTVLQSTNRKLERK 1086
Query: 316 ICN-KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ + +E++ + + + L L + K ++ E ++E
Sbjct: 1087 VKELSIQIEDERQHVNDQKDQL---SLRVKALKRQVDEAEEEIE 1127
Score = 36.3 bits (80), Expect = 0.32
Identities = 44/210 (20%), Positives = 94/210 (44%), Gaps = 9/210 (4%)
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE---LLQALEGA 226
A++ K L+ + +T+L ++ + + L + +DQ+ +++ ++ + Q LE
Sbjct: 966 ARQLKGLEEKVSRLETELDEE-KNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECD 1024
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +E K+L + + +E + L + + Q + +L+ E E+ + + +
Sbjct: 1025 KISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLE 1084
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELH 344
K L E E++ + ++ SLR + + EE++ +L + Q E H
Sbjct: 1085 RKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQH 1144
Query: 345 EAKVKLSSVESQLE--SWMSAARAHGVESA 372
E +L + LE SW A+R+ ESA
Sbjct: 1145 EVNEQLQARIKSLEKDSWRKASRS-AAESA 1173
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 54.0 bits (124), Expect = 2e-06
Identities = 90/388 (23%), Positives = 152/388 (39%), Gaps = 34/388 (8%)
Query: 5 SDMSLYSDVLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGS 64
+D + + L P R T PK AST + + S+ G S + G+ SS S
Sbjct: 114 TDTTAKTSKLAPTARKTTTRRPKPTRPASTGVAGASSSL----GPSGSASAGELSSSEPS 169
Query: 65 VDDVTPDKR--LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKE 122
TP + + PP P +K + +AQ+ LE ++ R E
Sbjct: 170 TPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEE----GLRAQVRDLEEKLETLRLKRAE 225
Query: 123 MQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDK 182
++ K +E+HK V + + E AKE + K + +
Sbjct: 226 -----DKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYME 280
Query: 183 EKTDLHKQI--ADLKDKLLEANVSNKDQ-ISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
E D I A L ++ E + Q + +K+ +DEL LE ++E+E K
Sbjct: 281 EMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE------K 334
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL-EYERDSYKDWQTQSKTAQKRL----CN 294
+ A QLK QLE+QN + ++++L E+ + Q + + L
Sbjct: 335 GSDGAASSYQLK-QLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ 393
Query: 295 MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
L++E+++ + L++ + L EE V LT R L+ EL E L ++
Sbjct: 394 RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMN 453
Query: 355 SQLESWMSAARAHGVESAGALRDALESA 382
+ AR +E LR+ L+ A
Sbjct: 454 EMNDELQENARETELE----LREQLDMA 477
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 54.0 bits (124), Expect = 2e-06
Identities = 84/371 (22%), Positives = 161/371 (43%), Gaps = 35/371 (9%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 364 ---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ V + L+ E + + E L E +K+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS--- 1015
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVAL 478
L ++ E++I L++RL R + RQ+L+ ++L T ++ A A
Sbjct: 1016 -KSLAKLKNKHEAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKL 533
++ QL K + + +A + A K AL+ +R ++++ +E+ E R K
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
Q+ L LE + +T++ ++ AA+ + + +E +E+ LK L E A+
Sbjct: 1131 EKQKRDLGEELEAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKT 1182
Query: 594 DPEELQQMRQQ 604
++Q+MRQ+
Sbjct: 1183 HEAQIQEMRQK 1193
Score = 41.1 bits (92), Expect = 0.011
Identities = 50/232 (21%), Positives = 106/232 (45%), Gaps = 15/232 (6%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 1209
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ +L A K LE + +L + V+ L + +++ K VE+QL+
Sbjct: 1210 RVKANLEKA---KQTLENERGELANEVKVLLQGK---GDSEHKRKKVEAQLQ 1255
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 54.0 bits (124), Expect = 2e-06
Identities = 84/371 (22%), Positives = 161/371 (43%), Gaps = 35/371 (9%)
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEV---TRLRAN 308
Q+ +Q E +L ++ ++ + ++ T+ +T Q +L +L++++ T L A
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 309 ERSLRDAI-CNKLLLEEQVHQLTSRV----EALQPVQLELHEAKVKLSSVESQLESWMSA 363
LR + K LEE H L +RV E Q +Q E + + + +E QLE SA
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESA 958
Query: 364 ---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK 420
+ V + L+ E + + E L E +K+
Sbjct: 959 RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS--- 1015
Query: 421 LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL--TVTLCGEEGAGSVAL 478
L ++ E++I L++RL R + RQ+L+ ++L T ++ A A
Sbjct: 1016 -KSLAKLKNKHEAMITDLEERL----RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 479 LSARVQQLEKSLQGYRDLIAAHDPHAHSK--ALESLR---NEVTRWREEAEGARRDVTKL 533
++ QL K + + +A + A K AL+ +R ++++ +E+ E R K
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKA 1130
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
Q+ L LE + +T++ ++ AA+ + + +E +E+ LK L E A+
Sbjct: 1131 EKQKRDLGEELEAL--KTELEDTLDSTAAQQELRSKRE-----QEVNILKKTLEE-EAKT 1182
Query: 594 DPEELQQMRQQ 604
++Q+MRQ+
Sbjct: 1183 HEAQIQEMRQK 1193
Score = 44.4 bits (100), Expect = 0.001
Identities = 67/331 (20%), Positives = 140/331 (42%), Gaps = 23/331 (6%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
L E+ +R+E+ ++E D+ + +LK K++ +L +A
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 194 LKDKLLEANVSNK------DQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQ 246
++++ + N++ K QISE+++D++ + A+ + L +EL +T +
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR 306
Q E ++ Q+V K LE E ++ + Q Q + QK + EL +++ + +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQ-EMRQKHSQAVEELAEQLEQTK 1209
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
+ +L A K LE + +L + V+ L + +++ K VE+QL+ +
Sbjct: 1210 RVKANLEKA---KQTLENERGELANEVKVLLQGK---GDSEHKRKKVEAQLQE-LQVKFN 1262
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
G L D + LT++ + L+ + L +
Sbjct: 1263 EGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE--- 1319
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+N++ L L +L V E++S+R+QL+
Sbjct: 1320 --ENRQKL--SLSTKLKQVEDEKNSFREQLE 1346
Score = 31.9 bits (69), Expect = 6.9
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDK 197
K+ F +E ++ K N +K+ LH Q+AD+K K
Sbjct: 1338 KNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
>AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein.
Length = 1257
Score = 54.0 bits (124), Expect = 2e-06
Identities = 94/469 (20%), Positives = 188/469 (40%), Gaps = 37/469 (7%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDER-AVSD 147
P E L +L A + Q+ + E ++ R ++L E + L+ +H+R R V
Sbjct: 100 PPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLEC-LVSRHERSLRMTVVK 158
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN---VS 204
+ + + HK L + ++++ L+++L AN V+
Sbjct: 159 RQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA 218
Query: 205 NKDQISEMKKDM--------DELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
++Q +++ M E L+ +E Q E L + T Q +L+ LE
Sbjct: 219 LREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLE 278
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
KQN+E Q+ +L L + + +++TA+K L E+ + +R +R+A
Sbjct: 279 KQNYEMAQMKERLAALS---SRVGEVEQEAETARKDLIKTEEMNTKY------QRDIREA 329
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGAL 375
+ K +EE++ L R + Q +H+ KL E++L + A E L
Sbjct: 330 MAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKL---ENELAN-KEAILRQMEEKNRQL 385
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQ-ESL 434
++ LE A L + +A L + ++ G + + + Q E
Sbjct: 386 QERLELAEEKLQQTMRKAETLPEVEAELAQRIAALT-KAEETHGNIEERMRHLEGQLEEK 444
Query: 435 IHRLQKRLLLVTRERDSYRQQLDCYEKELT-----VTLCGEEGAGSVALLSARVQQLEKS 489
LQ+ + ++ D ++ LT + L +E ++ + +Q+ E
Sbjct: 445 NQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETF 504
Query: 490 LQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
+ + + HD + ++ +E LR+E+ + + G+ + T RT D
Sbjct: 505 RKNLEE--SLHDKESLAEEIEKLRSELDQLKMRT-GSLIEPTIPRTHLD 550
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 53.6 bits (123), Expect = 2e-06
Identities = 67/261 (25%), Positives = 106/261 (40%), Gaps = 14/261 (5%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
LES HQ TI + EE +L + E + K+ T
Sbjct: 970 LESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT-QT 1028
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+ KD + + K Q + ++LE+ ++ K+Q+ K D+ E ++ Q
Sbjct: 1029 LTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL---KTDLKENIEMTIENQE 1085
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTA 288
E+ +L EL KQ E Q KN K+ E + +L E+E E+ K Q Q K
Sbjct: 1086 ELRLLGDELKKQQ---EIVAQEKNHAIKKEGELSRTCDRLAEVE-EKLKEKSQQLQEK-- 1139
Query: 289 QKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK- 347
Q++L N+ E E+ + +L++ + NK L E H T R+E Q + E K
Sbjct: 1140 QQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE--HMETERLELAQKLNENYEEVKS 1197
Query: 348 -VKLSSVESQLESWMSAARAH 367
K V +L+ R H
Sbjct: 1198 ITKERKVLKELQKSFETERDH 1218
Score = 49.2 bits (112), Expect = 4e-05
Identities = 98/529 (18%), Positives = 218/529 (41%), Gaps = 33/529 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K ++ L + + +L ++N + +E++ + +E K L E K E +
Sbjct: 1166 ELKNKELTLEHMETERLELAQKLNENY---EEVKSITKERKV-LKELQKSFETERDHLRG 1221
Query: 151 XXXXXXXXXXXXKDEFNTA---AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD 207
K+E A KEH++ + ++ QI + +D L +++ ++
Sbjct: 1222 YIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD-LEKSHTKLQE 1280
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN-QLEKQ--NFEFQQV 264
+I + ++ + L + ++++ M + EL+ + S + T L ++E+ N +FQ+
Sbjct: 1281 EIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQES 1340
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
++K L ERD+ K T + + + + E +E +S ++ N +
Sbjct: 1341 QEEIKSLTKERDNLK---TIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDN 1397
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
+ ++ S +E +P L ++++ + +L+ ++ E R L+ L
Sbjct: 1398 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQR--LQEVLQ 1455
Query: 385 XXXXXXXXXXXXXXXXXHLTEE---VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKR 441
TEE VA + + T +N+L +E+ I +QK+
Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEET--INELRVNLSEKETEISTIQKQ 1513
Query: 442 LLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHD 501
L + + + Q++ YEKE + + ++ + V +L K + +R +
Sbjct: 1514 LEAINDKLQNKIQEI--YEKEEQLNI------KQISEVQENVNEL-KQFKEHRKAKDSAL 1564
Query: 502 PHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
SK LE L N + +EE + ++ +++ ++ L +++ TK + +
Sbjct: 1565 QSIESKMLE-LTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKES 1623
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRI 610
E + Q K + A E +K+ + Q + ++L + EN R+
Sbjct: 1624 QEKEYQFLK-MTAVNETQEKM-CEIEHLKEQFETQKLNLENIETENIRL 1670
Score = 48.4 bits (110), Expect = 7e-05
Identities = 92/509 (18%), Positives = 222/509 (43%), Gaps = 45/509 (8%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAK--EHKDLKANWDKEKT 185
+E+ ++ E+ + VS+ME + + + E D + KEK
Sbjct: 1386 QEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKD 1445
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL + L+ + + + K+ +++ + +EL A + + E + + V + +
Sbjct: 1446 DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKET 1505
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
+ + ++ QLE N + Q +K++E+ YE++ + + S+ + N+ EL++
Sbjct: 1506 EISTIQKQLEAINDKLQ---NKIQEI-YEKEEQLNIKQISEVQE----NVNELKQFKEHR 1557
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV-EALQPVQLELHEAKVKLSSVESQLESWMSAA 364
+A + +L+ +E ++ +LT+R+ E+ + +Q+ + E K ++ V+ L+
Sbjct: 1558 KAKDSALQS-------IESKMLELTNRLQESQEEIQIMIKE-KEEMKRVQEALQIERDQL 1609
Query: 365 RAHGVESAGALRDALESALGXXXXXXXXXXXXXX-XXXHLTEEVATLKYERDKATGKLND 423
+ + E ++++ E HL E+ T K L +
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL-------NLEN 1662
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQ-------QLDCYEKELTVTLCGE-EGAGS 475
+ T ++H + + VT+ERD R + D ++ L T+ + E
Sbjct: 1663 IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE 1722
Query: 476 VALLSARVQQLEKSLQGYRDLIA--AHDPHAHSKALE----SLRNEVTRWREEAEGARRD 529
+ ++ +++ ++++ R +++ ++ K LE +L+ + + +EE A
Sbjct: 1723 LKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMH 1782
Query: 530 VTKLRTQRDLLTASL-ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALRE 588
+ + + D L + E+ + + N A+ Q++I +EL+A + ++ LK + E
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI-QELKANEHQLITLKKDVNE 1841
Query: 589 GGAQADPEELQQMRQQLENSRIKLKRYSI 617
Q E++Q+++Q+++ + L + I
Sbjct: 1842 --TQKKVSEMEQLKKQIKDQSLTLSKLEI 1868
Score = 47.6 bits (108), Expect = 1e-04
Identities = 48/270 (17%), Positives = 130/270 (48%), Gaps = 22/270 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX-- 162
++ + + + N + TI ++++ ++E+ ++ H ++ + D
Sbjct: 1699 KVERDQLKENLRETITRDLE---KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQ 1755
Query: 163 KD-EFNTAAKEHKDLKANWDKEKTDLH-KQIADLKDKLLEANVSNKDQISEMKKDMD--- 217
KD E + A + +DLK + +H K+ + DKL D++S M+KD++
Sbjct: 1756 KDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSN 1815
Query: 218 ----ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
E +Q L+ + ++ LKK++ + + + QLK Q++ Q+ ++ +++ L
Sbjct: 1816 AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL--EIENLNL 1873
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVH--QLT 330
++ +++ + + K+ K N+ +E+ + R + SL++ L +++++ ++
Sbjct: 1874 AQELHENLE-EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARML 1932
Query: 331 SR--VEALQPVQLELHEAKVKLSSVESQLE 358
S+ E + ++ ++ E +++S ++ L+
Sbjct: 1933 SKEHKETVDKLREKISEKTIQISDIQKDLD 1962
Score = 42.3 bits (95), Expect = 0.005
Identities = 48/263 (18%), Positives = 112/263 (42%), Gaps = 24/263 (9%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEH--KDLKANWDKEKTDLH-KQ 190
++ ++ + R+V+ D +D+ +E +DL+ + + +H K+
Sbjct: 1673 ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKE 1732
Query: 191 IADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA----QSEVEMLKKELVKQ------ 240
+ DKL ++IS M+KD++ AL+ Q E+ + L +Q
Sbjct: 1733 HQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDK 1792
Query: 241 -----TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM 295
+ + ++ + ++ LE N + Q+ +LK E++ + K ++ QK++ M
Sbjct: 1793 LRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET---QKKVSEM 1849
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
+L+K++ + +L L L +++H+ ++++ + L + L
Sbjct: 1850 EQLKKQI---KDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERD 1906
Query: 356 QLESWMSAARAHGVESAGALRDA 378
QL+ + +A +E L+ A
Sbjct: 1907 QLKESLQETKARDLEIQQELKTA 1929
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/90 (25%), Positives = 44/90 (48%)
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+SE L+KE+ K + EQ + KN+L N KE +R+++K ++
Sbjct: 2508 KSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENS 2567
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAI 316
++ A +K++T + ER+L+D +
Sbjct: 2568 PKSPKVTGTASKKKQITPSQCKERNLQDPV 2597
Score = 38.3 bits (85), Expect = 0.080
Identities = 69/289 (23%), Positives = 125/289 (43%), Gaps = 36/289 (12%)
Query: 74 LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM--QIL----F 127
+++D + E K + LI K + + + +V+ ++K++ Q L
Sbjct: 1807 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1866
Query: 128 EEEKASLIEQ-HKRDERAVSDME--DXXXXXXXXXXXXKDEFNTAAKEHK--DLKANWD- 181
E E +L ++ H+ E S M+ D +D+ + +E K DL+ +
Sbjct: 1867 EIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL 1926
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDM----DELLQALEGAQ-SEVEMLK-K 235
K L K+ + DKL E QIS+++KD+ DEL + ++ Q E+++L+ K
Sbjct: 1927 KTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVK 1986
Query: 236 ELVKQT-SRAEQCTQLKNQLE-----KQNFEFQQVTSKLKE-------LEYERDSYKDWQ 282
E V + + + QLK Q E K + Q+T KL E + ERD + +
Sbjct: 1987 EDVNMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIK 2046
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
K + + +A L + + R R N + + +LL + Q H + S
Sbjct: 2047 ESLKMERDQF--IATLREMIARDRQNHQVKPE---KRLLSDGQQHLMES 2090
Score = 35.1 bits (77), Expect = 0.75
Identities = 48/196 (24%), Positives = 87/196 (44%), Gaps = 25/196 (12%)
Query: 171 KEHKDLKANWDKEK--TDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
K KDL N + E TDL K++ +K +E N + ++++ LL L+ S
Sbjct: 707 KVPKDLLCNLELEGKITDLQKEL----NKEVEENEALREEVI--------LLSELKSLPS 754
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQSKT 287
EVE L+KE+ ++ T K++L + + +V L+E+ +D Q+ K+
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 288 AQKRLCNMAELEKEVTR-----LRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQL 341
+ N L + + L NER + I N L ++ + S + AL+ +
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEENER-MNQEIVN---LSKEAQKFDSSLGALKTELSY 870
Query: 342 ELHEAKVKLSSVESQL 357
+ E + K V+ +L
Sbjct: 871 KTQELQEKTREVQERL 886
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 53.6 bits (123), Expect = 2e-06
Identities = 102/517 (19%), Positives = 206/517 (39%), Gaps = 42/517 (8%)
Query: 112 RVNHQHTIRKEMQI--LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
R ++ + ++E Q +F+E+ +L E+ E+A ++++ + + +
Sbjct: 814 RERYEDSQQEEAQYGAMFQEQLMTLKEEC---EKARQELQEAKEKVAGIESHSELQISRQ 870
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
E +L AN + + ++ + KL + + +++++ K++ L + A +
Sbjct: 871 QNELAELHANLARALQQVQEKEVRAQ-KLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 929
Query: 230 VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQ 289
E +ELVK+ +RA Q + E+Q +F + L+ +E E + + + + A
Sbjct: 930 QETASRELVKEPARAGD-RQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Query: 290 -----KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
++ + E+EV RL ER A L LE+ +R E +Q L+
Sbjct: 989 MESQGQQQEERGQQEREVARL-TQERGRAQA---DLALEK-----AARAELEMRLQNALN 1039
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E +V+ ++++ L AH + L G L
Sbjct: 1040 EQRVEFATLQEAL--------AHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLK 1091
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E++A + E +G ++ + + L+ + + ++ ++Q D E+ L
Sbjct: 1092 EQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLE 1151
Query: 465 VTLCGEEGAGSV-----ALLSARVQQLEKS----LQGYRDLIAAHDP-HAHSKALESLRN 514
S L + Q+L S R+L A HSKA + +
Sbjct: 1152 AERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKA 1211
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISKELE 573
+V R R+EAE ++ L + +L LE+ G ++ L + ++QK + + L
Sbjct: 1212 QVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK-LEERLR 1270
Query: 574 AAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRI 610
Q E E + A EE+Q +R++ E R+
Sbjct: 1271 LLQAETASNSARAAE-RSSALREEVQSLREEAEKQRV 1306
Score = 50.4 bits (115), Expect = 2e-05
Identities = 102/499 (20%), Positives = 198/499 (39%), Gaps = 55/499 (11%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
K ES H K+ Q L + EK+ + + + D+ +D N
Sbjct: 284 KNESLTMRLHETLKQCQDL-KTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALN 342
Query: 168 TAAKEHKDLKANWDKEKTDLHKQI-ADLKDK--LLEANVSNKDQISEMKKDMDELLQALE 224
+EH W +++ L K++ A L+DK L E N + ++S++++ + +L
Sbjct: 343 ELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQD--N 400
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
Q + E+L L +T + E T N + Q ++++ LE ER Q +
Sbjct: 401 PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQ--------ARVEMLETERG-----QQE 447
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+K +R E+E +L + L+ +I N +E++ Q + A Q+
Sbjct: 448 AKLLAER----GHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQV--- 500
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
+S+ S+L + + + E AG + A E +
Sbjct: 501 ------ASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE 554
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ ++LK + + R++ + + RERD+ +QL+ EK
Sbjct: 555 QLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK--- 611
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALESLRNEVTRWREE 522
E A + +L ++Q ++ + + A + S+ +E L+ V R+E
Sbjct: 612 ------EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A+ V +L Q L + ++ + +V A+ + Q+ ++L+A +E +K
Sbjct: 666 QHEAQAQVAELELQ---LRSEQQKATEKERV--------AQEKDQLQEQLQALKESLKVT 714
Query: 583 KVALREGGAQ-ADPEELQQ 600
K +L E + AD E QQ
Sbjct: 715 KGSLEEEKRRAADALEEQQ 733
Score = 45.6 bits (103), Expect = 5e-04
Identities = 65/299 (21%), Positives = 122/299 (40%), Gaps = 34/299 (11%)
Query: 72 KRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
K+ + +SG+G + + T+ L A +A+++KLE + Q ++ E E+
Sbjct: 1096 KKEKEHASGSGAQSEAAG-RTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAER 1154
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKT 185
AS E+ E +E+ F T ++H + W K +
Sbjct: 1155 ASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEW-KAQV 1213
Query: 186 DLHKQIADLKDKLL-----EANVSNKDQISEMKKDMDEL--LQALEGAQSE-----VEML 233
+Q A+ K+ L+ E ++ N+ Q+ E + + EL L E +S+ + +L
Sbjct: 1214 ARGRQEAERKNSLISSLEEEVSILNR-QVLEKEGESKELKRLVMAESEKSQKLEERLRLL 1272
Query: 234 KKELVKQTSRA--------EQCTQLKNQLEKQNFEF----QQVTSKLKELEYERDSYKDW 281
+ E ++RA E+ L+ + EKQ Q++TS+ + E K W
Sbjct: 1273 QAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAW 1332
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
Q + ++ L + +LE T+ +E +C +L E+ + R E Q Q
Sbjct: 1333 QEKFFQKEQALSTL-QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQ 1390
Score = 44.8 bits (101), Expect = 0.001
Identities = 98/463 (21%), Positives = 193/463 (41%), Gaps = 55/463 (11%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
++E + ++ L+ L+E+ +++ + ++++ L Q AQ+++ + K
Sbjct: 971 EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEK------ 1024
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+RAE +L+N L +Q EF + L E++ KD + A+ R A++ K
Sbjct: 1025 AARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG-KD----QELAKLRGLEAAQI-K 1078
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL---QPVQLELHEAKVKLSSVESQL 357
E+ LR + L++ + K +E ++ EA +P +L + ++S +E Q
Sbjct: 1079 ELEELRQTVKQLKEQLAKKE--KEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQC 1136
Query: 358 ESWMSAA----RAHGVESAG-ALRD-ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ A R+ E A A RD ALE+ G E+A +
Sbjct: 1137 QKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFR 1196
Query: 412 ---YERDKATGKLNDLTTVRKNQE-----SLIHRLQKRLLLVTR---ERDSYRQQLDCY- 459
+ KA + R QE SLI L++ + ++ R E++ ++L
Sbjct: 1197 TKVQDHSKAEDEWK-AQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLV 1255
Query: 460 ----EK----ELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD-----LIAAHDPH--- 503
EK E + L E A + A + R L + +Q R+ +A+ +
Sbjct: 1256 MAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQEL 1315
Query: 504 -AHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAA 562
+ ++ E L E+ W+E+ + ++ L+ + A + + P + A
Sbjct: 1316 TSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQA 1375
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQL 605
A+K+ +ELE +++ L+ L AQ + EL +RQ++
Sbjct: 1376 AAEKRHREELEQSKQAAGGLRAELLR--AQRELGELIPLRQKV 1416
Score = 41.9 bits (94), Expect = 0.006
Identities = 38/172 (22%), Positives = 78/172 (45%), Gaps = 3/172 (1%)
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCT 248
KQ+ +L KL +++ ++K Q ++K + ++ + AQ ++ EL Q S+ EQ
Sbjct: 1549 KQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ-RLQAQLNELQAQLSQKEQAA 1607
Query: 249 Q-LKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLR 306
+ K Q+EK + + +EL+ + S + Q ++K + + EL++ + +
Sbjct: 1608 EHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK 1667
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
E++ R LE QV ++ L Q+ K + + QL+
Sbjct: 1668 EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLD 1719
Score = 40.7 bits (91), Expect = 0.015
Identities = 49/271 (18%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ L++ L + + + T+ E + +++++Q L E K + + RA +E+
Sbjct: 672 QVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEE 731
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
K E + ++HK + ++E+ L+ +L + +++ +
Sbjct: 732 QQRCISEL----KAETRSLVEQHKRERKELEEERAGRK----GLEARLQQLGEAHQAETE 783
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+++++ E + A A+SE E L KE+ R E Q + Q F+ Q +T K +E
Sbjct: 784 VLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAM-FQEQLMTLK-EE 841
Query: 271 LEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQ 328
E R ++ + + + ++ + E+ L AN R+L+ ++ ++
Sbjct: 842 CEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADD 901
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLES 359
L++ E + E+ + + Q E+
Sbjct: 902 LSTLQEKMAATSKEVARLETLVRKAGEQQET 932
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 53.6 bits (123), Expect = 2e-06
Identities = 105/473 (22%), Positives = 189/473 (39%), Gaps = 35/473 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L E+E A L EQ + + + ++E
Sbjct: 619 ESRSLSTELFKLK---NAYEEALDQLETVKRENKNL-EQEIADLTEQIAENGKTIHELEK 674
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKDLKA-----NWDKEKTDLHKQIADLKDKLLEANV 203
+ E AA EH++ K + K+++ ++IA+ KD+ +E
Sbjct: 675 SRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE-KDEEIEQLK 733
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
N + E M L A +E LKK++ + E Q + Q + +
Sbjct: 734 RNYQRTVET---MQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 790
Query: 263 QVTSKLKELEYERDS----YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
V +LK+ + D +D + Q ++R N+ L+ EV LRA A
Sbjct: 791 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERR-ANL--LQAEVEELRATLEQTERA--- 844
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGA 374
+ L E+++ RV+ L L K KL + ++S++E AR ++ A
Sbjct: 845 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 904
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A +L + V L++ D+A L + E+
Sbjct: 905 ITDAAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 963
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELT-VTLCGEEGAGSVALLSARVQQLEKSLQG 492
I L+ L ++ + L YE+ + +T EE +V L V +L+ ++
Sbjct: 964 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1023
Query: 493 YRDLIAAHDP--HAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Y+ D +AH ++E+ E A+ A V KLR + T+S
Sbjct: 1024 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1076
Score = 50.4 bits (115), Expect = 2e-05
Identities = 92/445 (20%), Positives = 184/445 (41%), Gaps = 30/445 (6%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KE T+ + ++ +L +D+ SE+KKD+D+L L + E + ++ T
Sbjct: 66 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 125
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSK-LKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+ +L ++ Q+ + L +L+ E D + +KT K + +LE
Sbjct: 126 EELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKV---NSLNKTKSKLEQQVEDLES 182
Query: 301 EVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
+ + E+ LR D NK LE + + L+ + +L E K QL+S
Sbjct: 183 SLEQ----EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQS 238
Query: 360 WMSAARAHGVESAGALRD---ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
+ + G++ +++ +E E+ L ++
Sbjct: 239 KVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE 298
Query: 417 ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV 476
A G + + K +E+ +L++ L T + ++ L + +V GE+ +
Sbjct: 299 AGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHAD-SVAELGEQ----I 353
Query: 477 ALLSARVQQLEKSLQGYR----DLIAAHDPHAHSKA-LE----SLRNEVTRWREEAEGAR 527
L Q+LEK ++ DL ++ + + SKA LE +L ++++ R + E +
Sbjct: 354 DNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQ 413
Query: 528 RDVTKLRTQRDLL---TASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
R +++L TQ+ L L R + + + + + +A Q ++EL+ EE K K
Sbjct: 414 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 473
Query: 585 ALREGGAQADPEELQQMRQQLENSR 609
AL Q+ + +R+Q E +
Sbjct: 474 ALGH-ALQSSRHDCDLLREQYEEEQ 497
Score = 49.2 bits (112), Expect = 4e-05
Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 14/199 (7%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD-E 218
KDE + + K+L+ +EK DL Q+ + LL+A DQ+ + K ++ +
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE-ERCDQLIKAKFQLEAK 64
Query: 219 LLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE-------KQNFEFQQVTSKLKEL 271
+ + E A+ E E+ + K+ ++C++LK ++ K E +K+K L
Sbjct: 65 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 124
Query: 272 EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTS 331
E +T +K +++ ++ + L+A E + K LE+QV L S
Sbjct: 125 TEELSGLD--ETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 332 RVEALQPVQLELHEAKVKL 350
+E + ++++L K KL
Sbjct: 183 SLEQEKKLRVDLERNKRKL 201
Score = 44.8 bits (101), Expect = 0.001
Identities = 54/246 (21%), Positives = 100/246 (40%), Gaps = 15/246 (6%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E + E A+L ++H + + D K EF + +
Sbjct: 325 EEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESV 384
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
K K +L K L+D+L EA N+ E+++ + EL Q+E L ++L ++
Sbjct: 385 SKSKANLEKICRTLEDQLSEARGKNE----EIQRSLSELTTQKSRLQTEAGELSRQLEEK 440
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
S + +QL + F Q T +LK E + K+ + + + C++ L +
Sbjct: 441 ES-------IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDL--LRE 491
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW 360
+ + + L+ A+ +K E + +A+Q + EL EAK KL+ E
Sbjct: 492 QYEEEQEGKAELQRAL-SKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDSEEQ 549
Query: 361 MSAARA 366
+ A A
Sbjct: 550 VEAVNA 555
Score = 42.7 bits (96), Expect = 0.004
Identities = 104/487 (21%), Positives = 198/487 (40%), Gaps = 46/487 (9%)
Query: 142 ERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKL 198
ERA D E+ +DE + K+ DL+ A +KEK ++ +L ++L
Sbjct: 70 ERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 128
Query: 199 LEANVSNKDQISEMKKDMDELLQALEGAQSE---VEMLKKELVKQTSRAEQCTQLKNQLE 255
+ + E K + QAL+ Q+E V L K K + E Q +
Sbjct: 129 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 188
Query: 256 KQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
K + ++ KL+ +L+ ++S D + + +RL + + E +L++ + D
Sbjct: 189 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL---KKKDFEYCQLQS---KVED 242
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA 374
L ++++ +L +R+E L+ E+ + + E Q + A +E
Sbjct: 243 EQTLGLQFQKKIKELQARIEELEE---EIEAERATRAKTEKQRSDY-----ARELEE--- 291
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTE--EVATLKYERDKATGKLNDLTTVRKNQE 432
L + LE A G L E ATL++E AT + +V + E
Sbjct: 292 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 351
Query: 433 SLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL-- 490
I LQ+ + +E+ ++ ++D +L+ ++ E + S A L + LE L
Sbjct: 352 Q-IDNLQRVKQKLEKEKSEFKLEID----DLSSSM--ESVSKSKANLEKICRTLEDQLSE 404
Query: 491 -QGYRDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
+G + I + + L++ E++R EE E V++L + T E +
Sbjct: 405 ARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESI---VSQLSRSKQAFTQQTEEL 461
Query: 548 GPQTKVLHLTNNP---AAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
Q + + N A ++ + L EE ++ K L+ ++A+ E+ Q R +
Sbjct: 462 KRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN-SEVAQWRTK 520
Query: 605 LENSRIK 611
E I+
Sbjct: 521 YETDAIQ 527
>BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein.
Length = 1236
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/277 (21%), Positives = 116/277 (41%), Gaps = 23/277 (8%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDER-AVSD 147
P E L +L A + Q+ + E ++ R ++L E + L+ +H+R R V
Sbjct: 100 PPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLEC-LVSRHERSLRMTVVK 158
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN---VS 204
+ + + HK L + ++++ L+++L AN V+
Sbjct: 159 RQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA 218
Query: 205 NKDQISEMKKDM--------DELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
++Q +++ M E L+ +E Q E L + T Q +L+ LE
Sbjct: 219 LREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLE 278
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
KQN+E Q+ +L L + + +++TA+K L E+ + +R +R+A
Sbjct: 279 KQNYEMAQMKERLAALS---SRVGEVEQEAETARKDLIKTEEMNTKY------QRDIREA 329
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS 352
+ K +EE++ L R + Q +H+ KL +
Sbjct: 330 MAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLEN 366
>AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 53.6 bits (123), Expect = 2e-06
Identities = 64/273 (23%), Positives = 114/273 (41%), Gaps = 20/273 (7%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDER-AVSD 147
P E L +L + Q+ + E ++ R ++L E + L+ +H+R R V
Sbjct: 77 PQEFATLTRELSMCREQLLEREEEISELKAERNNTRLLLEHLEC-LVSRHERSLRMTVVK 135
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD 207
+ + + HK L + +++ L+++L A+
Sbjct: 136 RQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRAALERVTTLEEQLAGAH----Q 191
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQ-TSRAEQCTQLKNQLEKQNFEFQQVTS 266
Q+S +++ A E + VE+ K L K+ T R E+ +L LEKQNFE Q
Sbjct: 192 QVSALQQGAGVRDGAAE-EEGTVELGPKRLWKEDTGRVEELQEL---LEKQNFELSQARE 247
Query: 267 KLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV 326
+L L + + + TA++ L EL + ++R LR+A+ K +EE++
Sbjct: 248 RLVTLT---TTVTELEEDLGTARRDLIKSEELSSK------HQRDLREALAQKEDMEERI 298
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
L R A Q +H+ KL + + ES
Sbjct: 299 TTLEKRYLAAQREATSIHDLNDKLENELANKES 331
>AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein
protein.
Length = 1258
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/277 (21%), Positives = 116/277 (41%), Gaps = 23/277 (8%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDER-AVSD 147
P E L +L A + Q+ + E ++ R ++L E + L+ +H+R R V
Sbjct: 111 PPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLEC-LVSRHERSLRMTVVK 169
Query: 148 MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN---VS 204
+ + + HK L + ++++ L+++L AN V+
Sbjct: 170 RQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA 229
Query: 205 NKDQISEMKKDM--------DELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
++Q +++ M E L+ +E Q E L + T Q +L+ LE
Sbjct: 230 LREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLE 289
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
KQN+E Q+ +L L + + +++TA+K L E+ + +R +R+A
Sbjct: 290 KQNYEMAQMKERLAALS---SRVGEVEQEAETARKDLIKTEEMNTKY------QRDIREA 340
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS 352
+ K +EE++ L R + Q +H+ KL +
Sbjct: 341 MAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLEN 377
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 53.6 bits (123), Expect = 2e-06
Identities = 102/517 (19%), Positives = 206/517 (39%), Gaps = 42/517 (8%)
Query: 112 RVNHQHTIRKEMQI--LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
R ++ + ++E Q +F+E+ +L E+ E+A ++++ + + +
Sbjct: 820 RERYEDSQQEEAQYGAMFQEQLMTLKEEC---EKARQELQEAKEKVAGIESHSELQISRQ 876
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
E +L AN + + ++ + KL + + +++++ K++ L + A +
Sbjct: 877 QNELAELHANLARALQQVQEKEVRAQ-KLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 935
Query: 230 VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQ 289
E +ELVK+ +RA Q + E+Q +F + L+ +E E + + + + A
Sbjct: 936 QETASRELVKEPARAGD-RQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 994
Query: 290 -----KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
++ + E+EV RL ER A L LE+ +R E +Q L+
Sbjct: 995 MESQGQQQEERGQQEREVARL-TQERGRAQA---DLALEK-----AARAELEMRLQNALN 1045
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E +V+ ++++ L AH + L G L
Sbjct: 1046 EQRVEFATLQEAL--------AHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLK 1097
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E++A + E +G ++ + + L+ + + ++ ++Q D E+ L
Sbjct: 1098 EQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLE 1157
Query: 465 VTLCGEEGAGSV-----ALLSARVQQLEKS----LQGYRDLIAAHDP-HAHSKALESLRN 514
S L + Q+L S R+L A HSKA + +
Sbjct: 1158 AERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKA 1217
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISKELE 573
+V R R+EAE ++ L + +L LE+ G ++ L + ++QK + + L
Sbjct: 1218 QVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK-LEERLR 1276
Query: 574 AAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRI 610
Q E E + A EE+Q +R++ E R+
Sbjct: 1277 LLQAETASNSARAAE-RSSALREEVQSLREEAEKQRV 1312
Score = 50.4 bits (115), Expect = 2e-05
Identities = 102/499 (20%), Positives = 198/499 (39%), Gaps = 55/499 (11%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
K ES H K+ Q L + EK+ + + + D+ +D N
Sbjct: 290 KNESLTMRLHETLKQCQDL-KTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALN 348
Query: 168 TAAKEHKDLKANWDKEKTDLHKQI-ADLKDK--LLEANVSNKDQISEMKKDMDELLQALE 224
+EH W +++ L K++ A L+DK L E N + ++S++++ + +L
Sbjct: 349 ELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQD--N 406
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
Q + E+L L +T + E T N + Q ++++ LE ER Q +
Sbjct: 407 PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQ--------ARVEMLETERG-----QQE 453
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+K +R E+E +L + L+ +I N +E++ Q + A Q+
Sbjct: 454 AKLLAER----GHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQV--- 506
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
+S+ S+L + + + E AG + A E +
Sbjct: 507 ------ASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE 560
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ ++LK + + R++ + + RERD+ +QL+ EK
Sbjct: 561 QLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK--- 617
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALESLRNEVTRWREE 522
E A + +L ++Q ++ + + A + S+ +E L+ V R+E
Sbjct: 618 ------EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 671
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A+ V +L Q L + ++ + +V A+ + Q+ ++L+A +E +K
Sbjct: 672 QHEAQAQVAELELQ---LRSEQQKATEKERV--------AQEKDQLQEQLQALKESLKVT 720
Query: 583 KVALREGGAQ-ADPEELQQ 600
K +L E + AD E QQ
Sbjct: 721 KGSLEEEKRRAADALEEQQ 739
Score = 45.6 bits (103), Expect = 5e-04
Identities = 65/299 (21%), Positives = 122/299 (40%), Gaps = 34/299 (11%)
Query: 72 KRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
K+ + +SG+G + + T+ L A +A+++KLE + Q ++ E E+
Sbjct: 1102 KKEKEHASGSGAQSEAAG-RTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAER 1160
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKT 185
AS E+ E +E+ F T ++H + W K +
Sbjct: 1161 ASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEW-KAQV 1219
Query: 186 DLHKQIADLKDKLL-----EANVSNKDQISEMKKDMDEL--LQALEGAQSE-----VEML 233
+Q A+ K+ L+ E ++ N+ Q+ E + + EL L E +S+ + +L
Sbjct: 1220 ARGRQEAERKNSLISSLEEEVSILNR-QVLEKEGESKELKRLVMAESEKSQKLEERLRLL 1278
Query: 234 KKELVKQTSRA--------EQCTQLKNQLEKQNFEF----QQVTSKLKELEYERDSYKDW 281
+ E ++RA E+ L+ + EKQ Q++TS+ + E K W
Sbjct: 1279 QAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAW 1338
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
Q + ++ L + +LE T+ +E +C +L E+ + R E Q Q
Sbjct: 1339 QEKFFQKEQALSTL-QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQ 1396
Score = 44.8 bits (101), Expect = 0.001
Identities = 98/463 (21%), Positives = 193/463 (41%), Gaps = 55/463 (11%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
++E + ++ L+ L+E+ +++ + ++++ L Q AQ+++ + K
Sbjct: 977 EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEK------ 1030
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+RAE +L+N L +Q EF + L E++ KD + A+ R A++ K
Sbjct: 1031 AARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG-KD----QELAKLRGLEAAQI-K 1084
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL---QPVQLELHEAKVKLSSVESQL 357
E+ LR + L++ + K +E ++ EA +P +L + ++S +E Q
Sbjct: 1085 ELEELRQTVKQLKEQLAKKE--KEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQC 1142
Query: 358 ESWMSAA----RAHGVESAG-ALRD-ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
+ A R+ E A A RD ALE+ G E+A +
Sbjct: 1143 QKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFR 1202
Query: 412 ---YERDKATGKLNDLTTVRKNQE-----SLIHRLQKRLLLVTR---ERDSYRQQLDCY- 459
+ KA + R QE SLI L++ + ++ R E++ ++L
Sbjct: 1203 TKVQDHSKAEDEWK-AQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLV 1261
Query: 460 ----EK----ELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD-----LIAAHDPH--- 503
EK E + L E A + A + R L + +Q R+ +A+ +
Sbjct: 1262 MAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQEL 1321
Query: 504 -AHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAA 562
+ ++ E L E+ W+E+ + ++ L+ + A + + P + A
Sbjct: 1322 TSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQA 1381
Query: 563 EAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQL 605
A+K+ +ELE +++ L+ L AQ + EL +RQ++
Sbjct: 1382 AAEKRHREELEQSKQAAGGLRAELLR--AQRELGELIPLRQKV 1422
Score = 41.9 bits (94), Expect = 0.006
Identities = 38/172 (22%), Positives = 78/172 (45%), Gaps = 3/172 (1%)
Query: 189 KQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCT 248
KQ+ +L KL +++ ++K Q ++K + ++ + AQ ++ EL Q S+ EQ
Sbjct: 1555 KQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ-RLQAQLNELQAQLSQKEQAA 1613
Query: 249 Q-LKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLR 306
+ K Q+EK + + +EL+ + S + Q ++K + + EL++ + +
Sbjct: 1614 EHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK 1673
Query: 307 ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
E++ R LE QV ++ L Q+ K + + QL+
Sbjct: 1674 EAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLD 1725
Score = 40.7 bits (91), Expect = 0.015
Identities = 49/271 (18%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ L++ L + + + T+ E + +++++Q L E K + + RA +E+
Sbjct: 678 QVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEE 737
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
K E + ++HK + ++E+ L+ +L + +++ +
Sbjct: 738 QQRCISEL----KAETRSLVEQHKRERKELEEERAGRK----GLEARLQQLGEAHQAETE 789
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+++++ E + A A+SE E L KE+ R E Q + Q F+ Q +T K +E
Sbjct: 790 VLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAM-FQEQLMTLK-EE 847
Query: 271 LEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQ 328
E R ++ + + + ++ + E+ L AN R+L+ ++ ++
Sbjct: 848 CEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADD 907
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLES 359
L++ E + E+ + + Q E+
Sbjct: 908 LSTLQEKMAATSKEVARLETLVRKAGEQQET 938
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 53.6 bits (123), Expect = 2e-06
Identities = 67/261 (25%), Positives = 106/261 (40%), Gaps = 14/261 (5%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
LES HQ TI + EE +L + E + K+ T
Sbjct: 950 LESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT-QT 1008
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+ KD + + K Q + ++LE+ ++ K+Q+ K D+ E ++ Q
Sbjct: 1009 LTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL---KTDLKENIEMTIENQE 1065
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTA 288
E+ +L EL KQ E Q KN K+ E + +L E+E E+ K Q Q K
Sbjct: 1066 ELRLLGDELKKQQ---EIVAQEKNHAIKKEGELSRTCDRLAEVE-EKLKEKSQQLQEK-- 1119
Query: 289 QKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK- 347
Q++L N+ E E+ + +L++ + NK L E H T R+E Q + E K
Sbjct: 1120 QQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE--HMETERLELAQKLNENYEEVKS 1177
Query: 348 -VKLSSVESQLESWMSAARAH 367
K V +L+ R H
Sbjct: 1178 ITKERKVLKELQKSFETERDH 1198
Score = 50.8 bits (116), Expect = 1e-05
Identities = 99/529 (18%), Positives = 218/529 (41%), Gaps = 33/529 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K ++ L + + +L ++N + +E++ + +E K L E K E +
Sbjct: 1146 ELKNKELTLEHMETERLELAQKLNENY---EEVKSITKERKV-LKELQKSFETERDHLRG 1201
Query: 151 XXXXXXXXXXXXKDEFNTA---AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD 207
K+E A KEH++ + ++ QI + +D L +++ ++
Sbjct: 1202 YIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD-LEKSHTKLQE 1260
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN-QLEKQ--NFEFQQV 264
+I + ++ + L E ++++ M + EL+ + S + T L ++E+ N +FQ+
Sbjct: 1261 EIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQES 1320
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
++K L ERD+ K T + + + + E +E +S ++ N +
Sbjct: 1321 QEEIKSLTKERDNLK---TIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDN 1377
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
+ ++ S +E +P L ++++ + +L+ ++ E R L+ L
Sbjct: 1378 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQR--LQEVLQ 1435
Query: 385 XXXXXXXXXXXXXXXXXHLTEE---VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKR 441
TEE VA + + T +N+L +E+ I +QK+
Sbjct: 1436 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEET--INELRVNLSEKETEISTIQKQ 1493
Query: 442 LLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHD 501
L + + + Q++ YEKE + ++ + +V +L K + +R +
Sbjct: 1494 LEAINDKLQNKIQEI--YEKEEQFNI------KQISEVQEKVNEL-KQFKEHRKAKDSAL 1544
Query: 502 PHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPA 561
SK LE L N + +EE + ++ +++ ++ L +++ TK + +
Sbjct: 1545 QSIESKMLE-LTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKES 1603
Query: 562 AEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRI 610
E + Q K + A E +K+ + Q + ++L + EN R+
Sbjct: 1604 QEKEYQFLK-MTAVNETQEKM-CEIEHLKEQFETQKLNLENIETENIRL 1650
Score = 47.6 bits (108), Expect = 1e-04
Identities = 92/509 (18%), Positives = 222/509 (43%), Gaps = 45/509 (8%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAK--EHKDLKANWDKEKT 185
+E+ ++ E+ + VS+ME + + + E D + KEK
Sbjct: 1366 QEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKD 1425
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL + L+ + + + K+ +++ + +EL A + + E + + V + +
Sbjct: 1426 DLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKET 1485
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
+ + ++ QLE N + Q +K++E+ YE++ + + S+ +K + EL++
Sbjct: 1486 EISTIQKQLEAINDKLQ---NKIQEI-YEKEEQFNIKQISEVQEK----VNELKQFKEHR 1537
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRV-EALQPVQLELHEAKVKLSSVESQLESWMSAA 364
+A + +L+ +E ++ +LT+R+ E+ + +Q+ + E K ++ V+ L+
Sbjct: 1538 KAKDSALQS-------IESKMLELTNRLQESQEEIQIMIKE-KEEMKRVQEALQIERDQL 1589
Query: 365 RAHGVESAGALRDALESALGXXXXXXXXXXXXXX-XXXHLTEEVATLKYERDKATGKLND 423
+ + E ++++ E HL E+ T K L +
Sbjct: 1590 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL-------NLEN 1642
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQ-------QLDCYEKELTVTLCGE-EGAGS 475
+ T ++H + + VT+ERD R + D ++ L T+ + E
Sbjct: 1643 IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE 1702
Query: 476 VALLSARVQQLEKSLQGYRDLIA--AHDPHAHSKALE----SLRNEVTRWREEAEGARRD 529
+ ++ +++ ++++ R +++ ++ K LE +L+ + + +EE A
Sbjct: 1703 LKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMH 1762
Query: 530 VTKLRTQRDLLTASL-ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALRE 588
+ + + D L + E+ + + N A+ Q++I +EL+A + ++ LK + E
Sbjct: 1763 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI-QELKANEHQLITLKKDVNE 1821
Query: 589 GGAQADPEELQQMRQQLENSRIKLKRYSI 617
Q E++Q+++Q+++ + L + I
Sbjct: 1822 --TQKKVSEMEQLKKQIKDQSLTLSKLEI 1848
Score = 46.4 bits (105), Expect = 3e-04
Identities = 48/270 (17%), Positives = 129/270 (47%), Gaps = 22/270 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX-- 162
++ + + + N + TI ++++ ++E+ ++ H ++ + D
Sbjct: 1679 KVERDQLKENLRETITRDLE---KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQ 1735
Query: 163 KD-EFNTAAKEHKDLKANWDKEKTDLH-KQIADLKDKLLEANVSNKDQISEMKKDMD--- 217
KD E + A + +DLK + +H K+ + DKL D++S M+KD++
Sbjct: 1736 KDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSN 1795
Query: 218 ----ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
E +Q L+ + ++ LKK++ + + + QLK Q++ Q+ ++ +++ L
Sbjct: 1796 AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL--EIENLNL 1853
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVH--QLT 330
+ +++ + + K+ K N+ +E+ + R + SL++ L +++++ ++
Sbjct: 1854 AQKLHENLE-EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARML 1912
Query: 331 SR--VEALQPVQLELHEAKVKLSSVESQLE 358
S+ E + ++ ++ E +++S ++ L+
Sbjct: 1913 SKEHKETVDKLREKISEKTIQISDIQKDLD 1942
Score = 42.3 bits (95), Expect = 0.005
Identities = 23/90 (25%), Positives = 44/90 (48%)
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+SE L+KE+ K + EQ + KN+L N KE +R+++K ++
Sbjct: 2430 KSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENS 2489
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAI 316
++ A +K++T + ER+L+D +
Sbjct: 2490 PKSPKVTGTASKKKQITPSQCKERNLQDPV 2519
Score = 41.9 bits (94), Expect = 0.006
Identities = 48/263 (18%), Positives = 112/263 (42%), Gaps = 24/263 (9%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEH--KDLKANWDKEKTDLH-KQ 190
++ ++ + R+V+ D +D+ +E +DL+ + + +H K+
Sbjct: 1653 ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKE 1712
Query: 191 IADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA----QSEVEMLKKELVKQ------ 240
+ DKL ++IS M+KD++ AL+ Q E+ + L +Q
Sbjct: 1713 HQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDK 1772
Query: 241 -----TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM 295
+ + ++ + ++ LE N + Q+ +LK E++ + K ++ QK++ M
Sbjct: 1773 LRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET---QKKVSEM 1829
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
+L+K++ + +L L L +++H+ ++++ + L + L
Sbjct: 1830 EQLKKQI---KDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD 1886
Query: 356 QLESWMSAARAHGVESAGALRDA 378
QL+ + +A +E L+ A
Sbjct: 1887 QLKESLQETKARDLEIQQELKTA 1909
Score = 36.3 bits (80), Expect = 0.32
Identities = 54/248 (21%), Positives = 105/248 (42%), Gaps = 22/248 (8%)
Query: 74 LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEM--QIL----F 127
+++D + E K + LI K + + + +V+ ++K++ Q L
Sbjct: 1787 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1846
Query: 128 EEEKASLIEQ-HKRDERAVSDME--DXXXXXXXXXXXXKDEFNTAAKEHK--DLKANWD- 181
E E +L ++ H+ E S M+ D +D+ + +E K DL+ +
Sbjct: 1847 EIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL 1906
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
K L K+ + DKL E QIS+++KD+D+ L+ Q K +
Sbjct: 1907 KTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLL 1966
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
S +Q L L ++ +++ + E++ D Y+ S +K + E +KE
Sbjct: 1967 SDGQQ--HLTESLREKCSRIKELLKRYSEMD---DHYECLNRLSLDLEKEI----EFQKE 2017
Query: 302 VT-RLRAN 308
++ R++AN
Sbjct: 2018 LSMRVKAN 2025
Score = 35.1 bits (77), Expect = 0.75
Identities = 48/196 (24%), Positives = 87/196 (44%), Gaps = 25/196 (12%)
Query: 171 KEHKDLKANWDKEK--TDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
K KDL N + E TDL K++ +K +E N + ++++ LL L+ S
Sbjct: 687 KVPKDLLCNLELEGKITDLQKEL----NKEVEENEALREEVI--------LLSELKSLPS 734
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQSKT 287
EVE L+KE+ ++ T K++L + + +V L+E+ +D Q+ K+
Sbjct: 735 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 794
Query: 288 AQKRLCNMAELEKEVTR-----LRANERSLRDAICNKLLLEEQVHQLTSRVEALQ-PVQL 341
+ N L + + L NER + I N L ++ + S + AL+ +
Sbjct: 795 TDQEFQNFKTLHMDFEQKYKMVLEENER-MNQEIVN---LSKEAQKFDSSLGALKTELSY 850
Query: 342 ELHEAKVKLSSVESQL 357
+ E + K V+ +L
Sbjct: 851 KTQELQEKTREVQERL 866
>AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparatus
protein 1 variant protein.
Length = 1585
Score = 53.6 bits (123), Expect = 2e-06
Identities = 102/517 (19%), Positives = 206/517 (39%), Gaps = 42/517 (8%)
Query: 112 RVNHQHTIRKEMQI--LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
R ++ + ++E Q +F+E+ +L E+ E+A ++++ + + +
Sbjct: 298 RERYEDSQQEEAQYGAMFQEQLMTLKEEC---EKARQELQEAKEKVAGIESHSELQISRQ 354
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE 229
E +L AN + + ++ + KL + + +++++ K++ L + A +
Sbjct: 355 QNELAELHANLARALQQVQEKEVRAQ-KLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 413
Query: 230 VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQ 289
E +ELVK+ +RA Q + E+Q +F + L+ +E E + + + + A
Sbjct: 414 QETASRELVKEPARAGD-RQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 472
Query: 290 -----KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
++ + E+EV RL ER A L LE+ +R E +Q L+
Sbjct: 473 MESQGQQQEERGQQEREVARL-TQERGRAQA---DLALEK-----AARAELEMRLQNALN 523
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E +V+ ++++ L AH + L G L
Sbjct: 524 EQRVEFATLQEAL--------AHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLK 575
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E++A + E +G ++ + + L+ + + ++ ++Q D E+ L
Sbjct: 576 EQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLE 635
Query: 465 VTLCGEEGAGSV-----ALLSARVQQLEKS----LQGYRDLIAAHDP-HAHSKALESLRN 514
S L + Q+L S R+L A HSKA + +
Sbjct: 636 AERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKA 695
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISKELE 573
+V R R+EAE ++ L + +L LE+ G ++ L + ++QK + + L
Sbjct: 696 QVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK-LEERLR 754
Query: 574 AAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRI 610
Q E E + A EE+Q +R++ E R+
Sbjct: 755 LLQAETASNSARAAE-RSSALREEVQSLREEAEKQRV 790
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/398 (20%), Positives = 156/398 (39%), Gaps = 35/398 (8%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQ-LKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
Q L G + + + + +L + + EQ +Q L++Q+E Q++S LK+ E +
Sbjct: 3 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE-------QLSSSLKQKEQQLKEVA 55
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR--DAI----CNKL-LLEEQVHQLTSR 332
+ Q ++ + A E+E + LR + +L+ +A+ KL +L++Q+
Sbjct: 56 EKQEATRQDHAQQLATAAEEREAS-LRERDAALKQLEALEKEKAAKLEILQQQLQVANEA 114
Query: 333 VEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXX 392
++ Q + K +LS +L++ + AR E+ + + LE L
Sbjct: 115 RDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAE-LELQLRSEQQKATE 173
Query: 393 XXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
L E++ LK G L + ++ + Q+ + + E S
Sbjct: 174 KERVAQEKDQLQEQLQALKESLKVTKGSLEE---EKRRAADALEEQQRCISELKAETRSL 230
Query: 453 RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI------AAHDPHAHS 506
+Q KEL G +G L AR+QQL ++ Q +++ A H
Sbjct: 231 VEQHKRERKELEEERAGRKG------LEARLQQLGEAHQAETEVLRRELAEAMAAQHTAE 284
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRT--QRDLLTASLERIGPQTKVLHLTNNPAAEA 564
E L EV WRE E ++++ + Q L+T E + L A
Sbjct: 285 SECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLK-EECEKARQELQEAKEKVAGI 343
Query: 565 QKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMR 602
+ ++ Q E+ +L L Q +E++ +
Sbjct: 344 ESHSELQISRQQNELAELHANLARALQQVQEKEVRAQK 381
Score = 46.4 bits (105), Expect = 3e-04
Identities = 112/568 (19%), Positives = 226/568 (39%), Gaps = 55/568 (9%)
Query: 72 KRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
K+ + +SG+G + + T+ L A +A+++KLE + Q ++ E E+
Sbjct: 580 KKEKEHASGSGAQSEAAG-RTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAER 638
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKT 185
AS E+ E +E+ F T ++H + W K +
Sbjct: 639 ASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEW-KAQV 697
Query: 186 DLHKQIADLKDKLL-----EANVSNKDQISEMKKDMDEL--LQALEGAQSE-----VEML 233
+Q A+ K+ L+ E ++ N+ Q+ E + + EL L E +S+ + +L
Sbjct: 698 ARGRQEAERKNSLISSLEEEVSILNR-QVLEKEGESKELKRLVMAESEKSQKLEERLRLL 756
Query: 234 KKELVKQTSRA--------EQCTQLKNQLEKQNFEF----QQVTSKLKELEYERDSYKDW 281
+ E ++RA E+ L+ + EKQ Q++TS+ + E K W
Sbjct: 757 QAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAW 816
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQL 341
Q + ++ L + +LE T+ +E +C +L E+ + R E L+ +
Sbjct: 817 QEKFFQKEQALSTL-QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHR-EELEQSKQ 874
Query: 342 ELHEAKVKLSSVESQLESWMSAAR--AHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ +L + +L + + A +A LR S
Sbjct: 875 AAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEE 934
Query: 400 XXHLTEEV----ATLKYERDKATGK-LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQ 454
L E L+ E D+A K + +L VR + E+ + +Q+ RE +
Sbjct: 935 NRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTA 994
Query: 455 QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
+ + ++ V + L+A+V++L K L + + L++++
Sbjct: 995 KYE--GAKVKVLEERQRFQEERQKLTAQVEELSKKLAD-----SDQASKVQQQKLKAVQA 1047
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ ++EA+ + + +L+ Q + E+ K+ +A+KQ ++EL+
Sbjct: 1048 QGGESQQEAQRLQAQLNELQAQ----LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE 1103
Query: 575 AQEEIKKLKVALREGGAQAD--PEELQQ 600
+++L+ +E A+A+ ELQQ
Sbjct: 1104 QLRSLEQLQKENKELRAEAERLGHELQQ 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/184 (21%), Positives = 83/184 (45%), Gaps = 3/184 (1%)
Query: 177 KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKE 236
+ + +E+ L Q+ +L KL +++ ++K Q ++K + ++ + AQ ++ E
Sbjct: 1007 RQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ-RLQAQLNE 1065
Query: 237 LVKQTSRAEQCTQ-LKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM 295
L Q S+ EQ + K Q+EK + + +EL+ + S + Q ++K + +
Sbjct: 1066 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERL 1125
Query: 296 A-ELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
EL++ + + E++ R LE QV ++ L Q+ K + +
Sbjct: 1126 GHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1185
Query: 355 SQLE 358
QL+
Sbjct: 1186 PQLD 1189
Score = 40.7 bits (91), Expect = 0.015
Identities = 49/271 (18%), Positives = 114/271 (42%), Gaps = 12/271 (4%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ L++ L + + + T+ E + +++++Q L E K + + RA +E+
Sbjct: 156 QVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEE 215
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
K E + ++HK + ++E+ L+ +L + +++ +
Sbjct: 216 QQRCISEL----KAETRSLVEQHKRERKELEEERAGRK----GLEARLQQLGEAHQAETE 267
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+++++ E + A A+SE E L KE+ R E Q + Q F+ Q +T K +E
Sbjct: 268 VLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAM-FQEQLMTLK-EE 325
Query: 271 LEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQ 328
E R ++ + + + ++ + E+ L AN R+L+ ++ ++
Sbjct: 326 CEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADD 385
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLES 359
L++ E + E+ + + Q E+
Sbjct: 386 LSTLQEKMAATSKEVARLETLVRKAGEQQET 416
>AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein.
Length = 864
Score = 53.6 bits (123), Expect = 2e-06
Identities = 93/524 (17%), Positives = 224/524 (42%), Gaps = 41/524 (7%)
Query: 121 KEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANW 180
+E+ E + ++ ++E+ ++ + ++ TA KE + K
Sbjct: 16 RELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEELLETADKELGEAKKEI 75
Query: 181 DKEKTDLHKQIADLKDKLLEANV--SNKDQISE---MKKDMDELLQALEGAQSEVEMLKK 235
++ +++ + LE N+ K+++S+ +K D++ ++ LE + + +
Sbjct: 76 KRKLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVE 135
Query: 236 ELV---KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY-KDWQTQSKTAQKR 291
+Q + + +L++ +++++ ++ + LK +E ERD Y K+ + Q+R
Sbjct: 136 SFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEEERDYYKKELERLQHIIQRR 195
Query: 292 LCNMAELEKEVTRL-RANERSLRDAICNKLLLE-EQVHQLTSRVEA-LQPVQLE---LHE 345
C+ + +E + + R E+ ++ +++ E +++ ++ R E ++ +Q L
Sbjct: 196 SCSTSYSAREKSSIFRTPEKGDYNSEIHQITRERDELQRMLERFEKYMEDIQSNVKLLTA 255
Query: 346 AKVKLSSVESQLESWMSAARAHGVES------AGALRDALESALGXXXXXXXXXXXXXXX 399
+ KLS + ++ + +SA R ++ + E AL
Sbjct: 256 ERDKLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREK 315
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
H+ E K E +K + LT V ES + L+ ++L++ +S +L
Sbjct: 316 LEHIEEVSLFGKSELEKT---IEHLTCVNHQLESEKYELKSKVLIMKETIESLENKLKVQ 372
Query: 460 EKELTVTLCGEEGAGSVALLSARV--QQLEKSLQGYRDLIA-----AHDPHAHSKALE-- 510
++ + + G+ + S R+ +QL++S+ Y+ ++ A K LE
Sbjct: 373 AQKFS-HVAGDSSHQKTEVNSLRIVNEQLQRSVDDYQHRLSIKRGELESAQAQIKILEEK 431
Query: 511 --SLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI 568
L ++T EEA ++ + + ++D L +++ K+ +L N A +K +
Sbjct: 432 IDELNLKMTSQDEEAHVMKKTIGVIDKEKDFLQETVDE--KTEKIANLQEN-LANKEKAV 488
Query: 569 SKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
+ +++ E + L+E D E+ +R+QL+ + +L
Sbjct: 489 A-QMKIMISECESSVNQLKETLVNRD-REINSLRRQLDAAHKEL 530
Score = 50.0 bits (114), Expect = 2e-05
Identities = 84/382 (21%), Positives = 156/382 (40%), Gaps = 35/382 (9%)
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+++K + EL++ E SEV L + K + QL QLE+ E + KE
Sbjct: 10 DLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEELLETAD--KE 67
Query: 271 LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLT 330
L + K ++ + ++ MA+L+ E+ + + L D + K LE VHQL
Sbjct: 68 LGEAKKEIKRKLSEMQDLEE---TMAKLQLELNLCQKEKERLSDELLVKSDLETVVHQLE 124
Query: 331 SRVEALQPVQLELHEAKVKLSSV-ESQLESWMSAAR-AHGVESAGALRDALESALGXXXX 388
+ L KV+ +V E QL + R HG++ L++ L
Sbjct: 125 QEKQRL--------SKKVESFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEE 176
Query: 389 XXXXXXXXXXXXXHLTE--EVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
H+ + +T R+K++ T + + S IH+ +T
Sbjct: 177 ERDYYKKELERLQHIIQRRSCSTSYSAREKSS---IFRTPEKGDYNSEIHQ-------IT 226
Query: 447 RERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHS 506
RERD ++ L+ +EK + E+ +V LL+A +L ++ ++A S
Sbjct: 227 RERDELQRMLERFEKYM------EDIQSNVKLLTAERDKLSVLYNEAQEELSA--LRKES 278
Query: 507 KALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ N V+ +E E A D+ ++ +++ L LE I + E
Sbjct: 279 TQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEKTIEHLT 338
Query: 567 QISKELEAAQEEIKKLKVALRE 588
++ +LE+ + E+K + ++E
Sbjct: 339 CVNHQLESEKYELKSKVLIMKE 360
Score = 46.8 bits (106), Expect = 2e-04
Identities = 77/372 (20%), Positives = 154/372 (41%), Gaps = 35/372 (9%)
Query: 181 DKEKTDLHKQIADLKDKL--LEANVSNKDQ--------ISEMKKDMDELLQALEGAQSEV 230
DKEK L + + + +K+ L+ N++NK++ ISE + +++L + L E+
Sbjct: 457 DKEKDFLQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREI 516
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQK 290
L+++L ++ + + K+N Q + + E + Q K K
Sbjct: 517 NSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEISLELEAAVQEKEEMK 576
Query: 291 RLCN--MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV 348
+ + E+ + + + A E+ +D L ++ L +R E +++ H+A+
Sbjct: 577 SRVHKYITEVSRWESLMAAKEKENQD-------LLDRFQMLHNRAE---DWEVKAHQAEG 626
Query: 349 KLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVA 408
+ SSV +L S + R H E L ++ + L EE
Sbjct: 627 ESSSVRLELLS-IDTERRHLRERVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEE-- 683
Query: 409 TLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLC 468
L+++ D+ LNDL+++R+ L +L ++T++ +S + + EL +
Sbjct: 684 -LRHQEDEKATVLNDLSSLRE----LCIKLDSGKDIMTQQLNSKNLEFERVVVELE-NVK 737
Query: 469 GEEGAGSVALLSAR--VQQLEKSLQGYRDL-IAAH-DPHAHSKALESLRNEVTRWREEAE 524
E L + R V+ LE L RD +H H ++ L+ ++T +
Sbjct: 738 SESDLLKKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDTEIQLLKEKLTLSESKLT 797
Query: 525 GARRDVTKLRTQ 536
R+ T LR +
Sbjct: 798 SQSRENTMLRAK 809
Score = 44.8 bits (101), Expect = 0.001
Identities = 75/423 (17%), Positives = 170/423 (40%), Gaps = 38/423 (8%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXK---D 164
K+ S+ H ++K + ++ ++EK L E ++++++ K
Sbjct: 438 KMTSQDEEAHVMKKTIGVI-DKEKDFLQETVDEKTEKIANLQENLANKEKAVAQMKIMIS 496
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN----------KDQISEMKK 214
E ++ + K+ N D+E L +Q+ +L E S +D ++ M +
Sbjct: 497 ECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMAR 556
Query: 215 DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYE 274
+ E+ LE A E E +K + K + + L EK+N Q + + + L
Sbjct: 557 ENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKEN---QDLLDRFQML--- 610
Query: 275 RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ +DW+ ++ A+ + + E+ + R LR+ + LLE+++ + +
Sbjct: 611 HNRAEDWEVKAHQAEG---ESSSVRLELLSIDTERRHLRERV---ELLEKEIQE---HIN 661
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
A + ++ +S +E +L +A + +LR+
Sbjct: 662 AHHAYESQISSMAKAMSRLEEELRH-QEDEKATVLNDLSSLRELCIKLDSGKDIMTQQLN 720
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL---LVTRERDS 451
+ E+ +K E D +L++ KN ESL+ + + L + E+D+
Sbjct: 721 SKNLEFERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDT 780
Query: 452 YRQQLDCYEKELTVTLCG-EEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALE 510
++ +++LT++ + +L A+V QL+ + I+ + + +A++
Sbjct: 781 ---EIQLLKEKLTLSESKLTSQSRENTMLRAKVAQLQTDYDALKRQIST-ERYERERAIQ 836
Query: 511 SLR 513
+R
Sbjct: 837 EMR 839
Score = 42.3 bits (95), Expect = 0.005
Identities = 91/505 (18%), Positives = 206/505 (40%), Gaps = 43/505 (8%)
Query: 122 EMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAK--EHKDLKAN 179
E Q+ E E+ L KR +R+ S ++ K E + + +
Sbjct: 141 ERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEEERDYYKKELERLQHIIQRRSCSTS 200
Query: 180 WD-KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ +EK+ + + + D E + +++ E+++ ++ + +E QS V++L E
Sbjct: 201 YSAREKSSIFRT-PEKGDYNSEIHQITRER-DELQRMLERFEKYMEDIQSNVKLLTAERD 258
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
K + + + + L K++ + + + +E E++ + ++ L E
Sbjct: 259 KLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEH 318
Query: 299 EKEVTRLRANE--RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+EV+ +E +++ C LE + ++L S+V ++ +E E K+K V++Q
Sbjct: 319 IEEVSLFGKSELEKTIEHLTCVNHQLESEKYELKSKVLIMKET-IESLENKLK---VQAQ 374
Query: 357 LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
S ++ +H +LR E L A +K +K
Sbjct: 375 KFSHVAGDSSHQKTEVNSLRIVNEQL---QRSVDDYQHRLSIKRGELESAQAQIKILEEK 431
Query: 417 ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD-CYEK--ELTVTLCGEEGA 473
+++L +Q+ H ++K + ++ +E+D ++ +D EK L L +E A
Sbjct: 432 ----IDELNLKMTSQDEEAHVMKKTIGVIDKEKDFLQETVDEKTEKIANLQENLANKEKA 487
Query: 474 GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKL 533
VA + + + E S+ ++ + D E+ R + + A +++ ++
Sbjct: 488 --VAQMKIMISECESSVNQLKETLVNRD------------REINSLRRQLDAAHKELDEV 533
Query: 534 RTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQA 593
R++ R+ + A ++IS ELEAA +E +++K + + +
Sbjct: 534 GRSREIAFKENRRLQDDLATM-------ARENQEISLELEAAVQEKEEMKSRVHKYITEV 586
Query: 594 DPEELQQMRQQLENSRIKLKRYSIV 618
E ++ EN + L R+ ++
Sbjct: 587 SRWESLMAAKEKENQDL-LDRFQML 610
Score = 34.7 bits (76), Expect = 0.98
Identities = 67/320 (20%), Positives = 125/320 (39%), Gaps = 23/320 (7%)
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR--VEALQPV 339
Q +K +KR+ + E ++ VT N + + +C +L +Q+ Q R E L+
Sbjct: 5 QQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEELLETA 64
Query: 340 QLELHEAK--VKLSSVESQ-LESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
EL EAK +K E Q LE M+ + + ++ L L
Sbjct: 65 DKELGEAKKEIKRKLSEMQDLEETMAKLQLE-LNLCQKEKERLSDELLVKSDLETVVHQL 123
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVR--KNQESLIHRLQKRLLLVTRERDSYRQ 454
L+++V + + T ++ + K ++ RL L + ERD Y++
Sbjct: 124 EQEKQRLSKKVESFAVTERQLTLEVERMRLEHGIKRRDRSPSRLDTFLKGIEEERDYYKK 183
Query: 455 QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
+L+ + + C + S S+ + EK Y I H ++ + L+
Sbjct: 184 ELERLQHIIQRRSCST--SYSAREKSSIFRTPEKG--DYNSEI-----HQITRERDELQR 234
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQIS---KE 571
+ R+ + E + +V L +RD L+ + L + +S KE
Sbjct: 235 MLERFEKYMEDIQSNVKLLTAERDKLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKE 294
Query: 572 LEAAQEEIKKL---KVALRE 588
E A +++++ K ALRE
Sbjct: 295 KELALSDLRRIMAEKEALRE 314
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 53.2 bits (122), Expect = 3e-06
Identities = 117/551 (21%), Positives = 236/551 (42%), Gaps = 62/551 (11%)
Query: 91 ETKRLKIDLIAAKAQ-ITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
ETKR + + K + I +L SR+ T +E++ E+ + + E+ E+A+S +
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL---EKALSTAQ 424
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ T K ++ + + +E + + +++ D+ K S+++QI
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK------SSEEQI 478
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF-------- 261
++++K L E A+ E E+ KK QT E Q+K LEK E+
Sbjct: 479 AKLQK-----LHEKELARKEQELTKK---LQTREREFQEQMKVALEKSQSEYLKISQEKE 530
Query: 262 QQVTSKLKELEYER--------DSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSL 312
QQ + L+ELE ++ + +D Q +++T + R+ + + LEK + + + L
Sbjct: 531 QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Query: 313 R---DAICNKLLLE--EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAH 367
+A NK E V + + +E+L+ Q L K+++ + Q E +
Sbjct: 591 AVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE 650
Query: 368 GVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E L+D E +++ E KA KL + +V
Sbjct: 651 -QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 428 RKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
K+Q + + L+ ++ +++ ++QQ+D KE V++ E A L ++ QL
Sbjct: 710 LKDQTDKMKQELEAKM---DEQKNHHQQQVDSIIKEHEVSIQRTEKA-----LKDQINQL 761
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA--------EGARRDVTKLRTQRD 538
E L+ + H H + + R+E + A + A + TK +
Sbjct: 762 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK-AYEEQ 820
Query: 539 LLTASLERIGPQTKVLHLTNNPA-AEAQKQ-ISKELEAAQEEIKKLKVALREGGAQADPE 596
L + + +T+ + LT A EAQK+ + EL+A + +++ L L + ++ + +
Sbjct: 821 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME-Q 879
Query: 597 ELQQMRQQLEN 607
+++ + Q E+
Sbjct: 880 KVKSLTQVYES 890
Score = 49.2 bits (112), Expect = 4e-05
Identities = 95/406 (23%), Positives = 184/406 (45%), Gaps = 44/406 (10%)
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
K ++ L Q ++ ++ ++ K+ + S EQCT L + EK+ + +Q+ +L+ELE
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETI---QSHKEQCTLLTS--EKEALQ-EQLDERLQELEK 332
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTS 331
+D + +T+ T + N+ E LE++ + A +R + + + K EE++ QL S
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK---EEEIAQLRS 389
Query: 332 RVEALQPVQLELHEAKVKLS-SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXX 390
R++ + EL E K K + +LE +S A+ E+ L+ ++ +
Sbjct: 390 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ-KTEEARRKLKAEMDEQIKTIEKTS 448
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK-RLLLVTRER 449
EE +L+ E + ++ D+ ++K+ E I +LQK + R+
Sbjct: 449 -------------EEERISLQQELSRVKQEVVDV--MKKSSEEQIAKLQKLHEKELARKE 493
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKA 508
++L E+E + VAL ++ + L+ S + ++ +A + KA
Sbjct: 494 QELTKKLQTREREFQEQM-------KVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546
Query: 509 -LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
L N++ ++EAE R + +L + L SL+ Q+K L + AE K
Sbjct: 547 ILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSK--DLAVHLEAEKNKH 601
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+KE+ E+ K +L+ E+LQ ++QQ + KL+
Sbjct: 602 -NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLR 646
Score = 46.4 bits (105), Expect = 3e-04
Identities = 54/253 (21%), Positives = 111/253 (43%), Gaps = 16/253 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTI-RKEMQILFEE-EKASLIEQHKRDERAVSDM 148
+ K L ++ K I +L+S + Q + R EM+ L + EK ++Q + +
Sbjct: 1843 QEKELTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELL 1900
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSN 205
E+ + +H DL+ A ++EK L K+I L+ L +
Sbjct: 1901 EENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1960
Query: 206 KDQISEMKKDMD-ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+ ++ +KK+ D E + ++ Q ++E+ +KQ R E TQL + ++ ++
Sbjct: 1961 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR-EFNTQLAQKEQELEMTIKET 2019
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+K +E+E E ++ + + L +AE + ++ R + DA + +
Sbjct: 2020 INKAQEVEAEL-----LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA--REEEMTA 2072
Query: 325 QVHQLTSRVEALQ 337
+V L +++E LQ
Sbjct: 2073 KVRDLQTQLEELQ 2085
Score = 45.2 bits (102), Expect = 7e-04
Identities = 89/447 (19%), Positives = 177/447 (39%), Gaps = 38/447 (8%)
Query: 185 TDLHKQIADLKDKLLEANVSNKD---QISEMKKDMDELLQALEGAQSEVEMLKKELVKQ- 240
++L Q+ L ++ N+S + Q+ E + + + +E +E E L+KE Q
Sbjct: 1272 SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQ 1331
Query: 241 --TSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
S E C TQLK +L + + +LKE + E S T + +++E
Sbjct: 1332 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E ++ LR + + C L +QV L+ +V+ L ++ E ++ ++
Sbjct: 1392 KEAAISSLR---KQYDEEKCELL---DQVQDLSFKVDTLSKEKISALE---QVDDWSNKF 1442
Query: 358 ESWMSAARAHGVESAGALRD---ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYE- 413
W A++ + +++ LE + LK E
Sbjct: 1443 SEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 414 ---RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS-------YRQQLDCYEKEL 463
+ K K ++L T K+Q + I L+ + T E +S Y QQ D KEL
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLR-NEVTRWREE 522
L + G RV++ E+ + + + + +K E N + +EE
Sbjct: 1563 VQKLQHFQELGEEK--DNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1620
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A D +L ++ A L+R Q K+ + ++ +++ + + + + +L
Sbjct: 1621 ELKALED--RLESESAAKLAELKRKAEQ-KIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
L+E + + L++ + +E+S+
Sbjct: 1678 NTKLQE--REREVHILEEKLKSVESSQ 1702
Score = 42.7 bits (96), Expect = 0.004
Identities = 94/530 (17%), Positives = 209/530 (39%), Gaps = 50/530 (9%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L+ +L K Q K++ + + +K +++ S+I++H E ++ E
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMDEQKNHH---QQQVDSIIKEH---EVSIQRTEKALK 755
Query: 154 XXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
E + KEH+ +L+A+ + + +L + A L D + +Q
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQT 814
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLK----------NQLEKQN 258
++ + +L Q L ++E +L K++ + + + + CT+L QLEKQN
Sbjct: 815 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 874
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
E +Q L ++ YE + Q +T Q + E E + ++R ++ + +
Sbjct: 875 SEMEQKVKSLTQV-YESKLEDGNKEQEQTKQ----ILVEKENMILQMREGQKKEIEILTQ 929
Query: 319 KL-LLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
KL E+ +H L E + + ++ + K K ++ L+ + A +
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE--N 987
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
ALE + +++ V+ L+ + + ++ LT V + + + +
Sbjct: 988 TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE---QIESLTEVHRRELNDVI 1044
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
+ ++ L E ++ EKE V E + L +++ K + ++
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEVA----ELKQKILLFGCEKEEMNKEITWLKEE 1100
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-----ERIGPQT 551
D L L+ ++ + +D TKL+ + L L E Q
Sbjct: 1101 GVKQD-----TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQE 1155
Query: 552 KVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVALREGGAQADPEELQ 599
+++ L + +K +++ +L+ EE + LK + + + + L+
Sbjct: 1156 QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Score = 42.3 bits (95), Expect = 0.005
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 19/251 (7%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHK--DLKAN---WDK 182
+E+ SL E H+R+ V + + E KE + +LK +
Sbjct: 1026 KEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1085
Query: 183 EKTDLHKQIADLKDKLLEANVSN---KDQISEMKKDMDELLQALEGAQSEVEMLK----K 235
EK +++K+I LK++ ++ + + ++Q+ + ++ L Q ++ +E L+ K
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1145
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS-KTAQKRLCN 294
L + T EQ +LK E+ + ++TSKLK + E S K +S K+ + +
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Query: 295 MAELEKEVT-RLR---ANERSLRDAICNKL--LLEEQVHQLTSRVEALQPVQLELHEAKV 348
+L +E+ +L +L +A N+L + + + + SR+ Q ++ EA +
Sbjct: 1206 FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1265
Query: 349 KLSSVESQLES 359
+ S+LE+
Sbjct: 1266 IKTCTVSELEA 1276
Score = 39.1 bits (87), Expect = 0.046
Identities = 49/257 (19%), Positives = 106/257 (41%), Gaps = 20/257 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
K L+I L + + + ++N + F+ K + + + E+ S++E
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETEL 1520
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+D E + L N++++K HK++ E +++
Sbjct: 1521 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRV 1580
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKEL----VKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
E ++ + L + ++E+E KKEL + S+ E+ L+++LE ++
Sbjct: 1581 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES------A 1634
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ 325
+KL EL+ + + + +K+L + E EKE + E L + E +
Sbjct: 1635 AKLAELKRKAEQ------KIAAIKKQLLSQME-EKEEQYKKGTESHLSELNTKLQERERE 1687
Query: 326 VHQLTSRVEALQPVQLE 342
VH L ++++++ Q E
Sbjct: 1688 VHILEEKLKSVESSQSE 1704
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 53.2 bits (122), Expect = 3e-06
Identities = 89/379 (23%), Positives = 161/379 (42%), Gaps = 37/379 (9%)
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRA 307
QL +L+K+ FE + SK+++ E+ Q + K Q R+ + E+E E T RA
Sbjct: 16 QLDEKLKKKEFEMSGLQSKIED---EQALGMQLQKKIKELQARIEELEEEIEAERTS-RA 71
Query: 308 NERSLRDAICNKL-----LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
LR + +L LEE V ++++E + + E + + L Q E+ +
Sbjct: 72 KAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATAA 131
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT---EEVATLKYERDK--- 416
R +S L + +++ L E V+ K +K
Sbjct: 132 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCR 191
Query: 417 -ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+L+++ T + Q+ LI+ L + + + + Y +QLD EK+ TL + G
Sbjct: 192 ALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLD--EKD---TLETQLSRGK 246
Query: 476 VALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT 535
A QQ+E+ + + I A AH AL+S R++ RE+ E K
Sbjct: 247 QAF----TQQIEELKRQLEEEIKAKSALAH--ALQSSRHDCDLLREQYE--EEQEAKAEL 298
Query: 536 QRDLLTASLE----RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL--KVALREG 589
QR + A+ E R +T + T EA+K++++ L+ A+E ++ + K A E
Sbjct: 299 QRAMSKANSEVAQWRTKYETDAIQRTEE-LEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 357
Query: 590 GAQADPEELQQMRQQLENS 608
Q E++ + +E +
Sbjct: 358 TKQRLQNEVEDLMIDVERT 376
Score = 46.0 bits (104), Expect = 4e-04
Identities = 89/437 (20%), Positives = 162/437 (37%), Gaps = 40/437 (9%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTS 242
EK L Q++ K + K Q+ E K L AL+ ++ + ++L+++ ++
Sbjct: 234 EKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ- 292
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEV 302
E +L+ + K N E Q +K YE D+ + + + +K + + E+ V
Sbjct: 293 --EAKAELQRAMSKANSEVAQWRTK-----YETDAIQRTEELEEAKKKLAQRLQDAEEHV 345
Query: 303 TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW-M 361
+ A SL K L+ +V L VE L + + + L W
Sbjct: 346 EAVNAKCASLEKT---KQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKI---LAEWKQ 399
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
H V LES +++ TLK E ++
Sbjct: 400 KCEETHAV---------LESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEI 450
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSA 481
+DLT IH L+K V +E+ + L+ E L E G + +
Sbjct: 451 SDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASL------EHEEGKILRIQL 504
Query: 482 RVQQLEKSLQ---GYRDLIAAHDPHAHSKALESLR---NEVTRWREEAEGARRDVTKLRT 535
V Q++ + +D H + ES++ N R R +A ++ +
Sbjct: 505 EVNQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLN 564
Query: 536 QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA---Q 592
+ ++ R+ + + + N A Q+ + +E K ++A+ E A Q
Sbjct: 565 EMEIQLNHANRMAAE-DLRNYQNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQ 623
Query: 593 ADPEELQQMRQQLENSR 609
A+ EEL+ +Q E SR
Sbjct: 624 AEIEELRATLEQTERSR 640
Score = 45.6 bits (103), Expect = 5e-04
Identities = 94/472 (19%), Positives = 197/472 (41%), Gaps = 47/472 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E++ L +L K E ++ T+++E + L ++E + L EQ + + ++E
Sbjct: 414 ESRSLSTELFKIK---NAYEESLDQLETLKRENKNL-QQEISDLTEQIAEGGKRIHELEK 469
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD-----LKANWDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ ++ ++ K+++ ++IA+ KD+ ++
Sbjct: 470 IKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAE-KDEEIDQMK 528
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE-FQ 262
N +I E M L A ++++ LKK++ + E N++ ++ +Q
Sbjct: 529 RNHIRIEE---SMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQ 585
Query: 263 QVTSKLKELEYERD----SYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ LK+ + D S +D + Q ++R N+ L+ E+ LRA +L +
Sbjct: 586 NTQAILKDTQLHLDDALRSQEDLKEQLAMVERR-ANL--LQAEIEELRA---TLEQTERS 639
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSS----VESQLESWMSAARAHGVESAGA 374
+ + E+++ + RV+ L L K KL + ++ ++E + AR ++ A
Sbjct: 640 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKA 699
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT------GK--LNDLTT 426
+ DA A +L + V L++ D+A GK + L
Sbjct: 700 ITDAAMMA-EELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 758
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
+ E + QKR + + + +++ KELT EE ++ L V +L
Sbjct: 759 KVRELEGEVESEQKRNVEAVKGLHKHERKV----KELTYQT--EEDRKNILRLQDLVDKL 812
Query: 487 EKSLQGYRDLI--AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ 536
+ ++ Y+ A + + +++E+ E A+ A V KLR +
Sbjct: 813 QAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVK 864
Score = 45.2 bits (102), Expect = 7e-04
Identities = 106/532 (19%), Positives = 213/532 (40%), Gaps = 45/532 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L ID+ A L+ + + I E + EE A ++E +++ R++S
Sbjct: 365 EVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETHA-VLESFQKESRSLST--- 420
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
D+ T +E+K+L+ +E +DL +QIA+ ++ E K
Sbjct: 421 ELFKIKNAYEESLDQLETLKRENKNLQ----QEISDLTEQIAEGGKRIHELEKIKK---- 472
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLK 269
+++++ EL ALE A++ +E + ++++ Q +++ ++ +++ E Q+
Sbjct: 473 QVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHI 532
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAE---LEKEVTRLRANERSLRDAI----CNKLLL 322
+E S + + +S+ RL E E E+ AN + D +L
Sbjct: 533 RIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILK 592
Query: 323 EEQVHQLTSRVEALQPV--QLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDAL 379
+ Q+H L + + + + QL + E + L E +L + + + L DA
Sbjct: 593 DTQLH-LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 651
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLTE---EVATLKYERDKATGKLNDLTTVRKNQESLIH 436
E +++ E+ + E A K T +
Sbjct: 652 ERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELK 711
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELTVT--LCGEEGAGSVALLSARVQQLEKSLQGY- 493
+ Q + R + + Q + + L L + G + L A+V++LE ++
Sbjct: 712 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQ 771
Query: 494 -RDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTK 552
R++ A H H + ++ E+T EE R+++ +L+ D L A ++ Q +
Sbjct: 772 KRNVEAVKGLHKHERKVK----ELTYQTEED---RKNILRLQDLVDKLQAKVKSYKRQAE 824
Query: 553 VLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALREGGAQADPEE 597
+N ++I ELE A+E ++ KL+V RE + EE
Sbjct: 825 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 876
Score = 41.5 bits (93), Expect = 0.009
Identities = 59/288 (20%), Positives = 119/288 (41%), Gaps = 21/288 (7%)
Query: 91 ETKRLKIDLIAAKAQIT-KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRD-ERAVSDM 148
+ ++L+ DL +I+ +LE V T QI +++ + ++ +RD E A
Sbjct: 72 KAEKLRSDLSRELEEISERLEEAVGATST-----QIEMNKKREAEFQKMRRDLEEATLQH 126
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-----LEANV 203
E E + +K +KEK+++ +I DL + + N+
Sbjct: 127 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 186
Query: 204 SN-----KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQN 258
+DQ+SE+K +E + + ++ L++ V+ + + ++ L+ QL +
Sbjct: 187 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGK 246
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
F Q +LK E K + + + C++ L ++ + + L+ A+ +
Sbjct: 247 QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL--LREQYEEEQEAKAELQRAM-S 303
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA 366
K E + +A+Q + EL EAK KL+ E + A A
Sbjct: 304 KANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDAEEHVEAVNA 350
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 53.2 bits (122), Expect = 3e-06
Identities = 117/551 (21%), Positives = 236/551 (42%), Gaps = 62/551 (11%)
Query: 91 ETKRLKIDLIAAKAQ-ITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
ETKR + + K + I +L SR+ T +E++ E+ + + E+ E+A+S +
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL---EKALSTAQ 424
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ T K ++ + + +E + + +++ D+ K S+++QI
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK------SSEEQI 478
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF-------- 261
++++K L E A+ E E+ KK QT E Q+K LEK E+
Sbjct: 479 AKLQK-----LHEKELARKEQELTKK---LQTREREFQEQMKVALEKSQSEYLKISQEKE 530
Query: 262 QQVTSKLKELEYER--------DSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSL 312
QQ + L+ELE ++ + +D Q +++T + R+ + + LEK + + + L
Sbjct: 531 QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Query: 313 R---DAICNKLLLE--EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAH 367
+A NK E V + + +E+L+ Q L K+++ + Q E +
Sbjct: 591 AVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE 650
Query: 368 GVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E L+D E +++ E KA KL + +V
Sbjct: 651 -QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 428 RKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
K+Q + + L+ ++ +++ ++QQ+D KE V++ E A L ++ QL
Sbjct: 710 LKDQTDKMKQELEAKM---DEQKNHHQQQVDSIIKEHEVSIQRTEKA-----LKDQINQL 761
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA--------EGARRDVTKLRTQRD 538
E L+ + H H + + R+E + A + A + TK +
Sbjct: 762 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK-AYEEQ 820
Query: 539 LLTASLERIGPQTKVLHLTNNPA-AEAQKQ-ISKELEAAQEEIKKLKVALREGGAQADPE 596
L + + +T+ + LT A EAQK+ + EL+A + +++ L L + ++ + +
Sbjct: 821 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME-Q 879
Query: 597 ELQQMRQQLEN 607
+++ + Q E+
Sbjct: 880 KVKSLTQVYES 890
Score = 49.2 bits (112), Expect = 4e-05
Identities = 95/406 (23%), Positives = 184/406 (45%), Gaps = 44/406 (10%)
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
K ++ L Q ++ ++ ++ K+ + S EQCT L + EK+ + +Q+ +L+ELE
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETI---QSHKEQCTLLTS--EKEALQ-EQLDERLQELEK 332
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTS 331
+D + +T+ T + N+ E LE++ + A +R + + + K EE++ QL S
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK---EEEIAQLRS 389
Query: 332 RVEALQPVQLELHEAKVKLS-SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXX 390
R++ + EL E K K + +LE +S A+ E+ L+ ++ +
Sbjct: 390 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ-KTEEARRKLKAEMDEQIKTIEKTS 448
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK-RLLLVTRER 449
EE +L+ E + ++ D+ ++K+ E I +LQK + R+
Sbjct: 449 -------------EEERISLQQELSRVKQEVVDV--MKKSSEEQIAKLQKLHEKELARKE 493
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKA 508
++L E+E + VAL ++ + L+ S + ++ +A + KA
Sbjct: 494 QELTKKLQTREREFQEQM-------KVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546
Query: 509 -LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
L N++ ++EAE R + +L + L SL+ Q+K L + AE K
Sbjct: 547 ILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSK--DLAVHLEAEKNKH 601
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+KE+ E+ K +L+ E+LQ ++QQ + KL+
Sbjct: 602 -NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLR 646
Score = 46.4 bits (105), Expect = 3e-04
Identities = 54/253 (21%), Positives = 111/253 (43%), Gaps = 16/253 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTI-RKEMQILFEE-EKASLIEQHKRDERAVSDM 148
+ K L ++ K I +L+S + Q + R EM+ L + EK ++Q + +
Sbjct: 1843 QEKELTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELL 1900
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSN 205
E+ + +H DL+ A ++EK L K+I L+ L +
Sbjct: 1901 EENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1960
Query: 206 KDQISEMKKDMD-ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+ ++ +KK+ D E + ++ Q ++E+ +KQ R E TQL + ++ ++
Sbjct: 1961 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR-EFNTQLAQKEQELEMTIKET 2019
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+K +E+E E ++ + + L +AE + ++ R + DA + +
Sbjct: 2020 INKAQEVEAEL-----LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA--REEEMTA 2072
Query: 325 QVHQLTSRVEALQ 337
+V L +++E LQ
Sbjct: 2073 KVRDLQTQLEELQ 2085
Score = 45.2 bits (102), Expect = 7e-04
Identities = 89/447 (19%), Positives = 177/447 (39%), Gaps = 38/447 (8%)
Query: 185 TDLHKQIADLKDKLLEANVSNKD---QISEMKKDMDELLQALEGAQSEVEMLKKELVKQ- 240
++L Q+ L ++ N+S + Q+ E + + + +E +E E L+KE Q
Sbjct: 1272 SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQ 1331
Query: 241 --TSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
S E C TQLK +L + + +LKE + E S T + +++E
Sbjct: 1332 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E ++ LR + + C L +QV L+ +V+ L ++ E ++ ++
Sbjct: 1392 KEAAISSLR---KQYDEEKCELL---DQVQDLSFKVDTLSKEKISALE---QVDDWSNKF 1442
Query: 358 ESWMSAARAHGVESAGALRD---ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYE- 413
W A++ + +++ LE + LK E
Sbjct: 1443 SEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1502
Query: 414 ---RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS-------YRQQLDCYEKEL 463
+ K K ++L T K+Q + I L+ + T E +S Y QQ D KEL
Sbjct: 1503 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLR-NEVTRWREE 522
L + G RV++ E+ + + + + +K E N + +EE
Sbjct: 1563 VQKLQHFQELGEEK--DNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1620
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A D +L ++ A L+R Q K+ + ++ +++ + + + + +L
Sbjct: 1621 ELKALED--RLESESAAKLAELKRKAEQ-KIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
L+E + + L++ + +E+S+
Sbjct: 1678 NTKLQE--REREVHILEEKLKSVESSQ 1702
Score = 42.7 bits (96), Expect = 0.004
Identities = 94/530 (17%), Positives = 209/530 (39%), Gaps = 50/530 (9%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L+ +L K Q K++ + + +K +++ S+I++H E ++ E
Sbjct: 702 KLEEELSVLKDQTDKMKQELEAKMDEQKNHH---QQQVDSIIKEH---EVSIQRTEKALK 755
Query: 154 XXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
E + KEH+ +L+A+ + + +L + A L D + +Q
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQT 814
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLK----------NQLEKQN 258
++ + +L Q L ++E +L K++ + + + + CT+L QLEKQN
Sbjct: 815 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 874
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
E +Q L ++ YE + Q +T Q + E E + ++R ++ + +
Sbjct: 875 SEMEQKVKSLTQV-YESKLEDGNKEQEQTKQ----ILVEKENMILQMREGQKKEIEILTQ 929
Query: 319 KL-LLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
KL E+ +H L E + + ++ + K K ++ L+ + A +
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE--N 987
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
ALE + +++ V+ L+ + + ++ LT V + + + +
Sbjct: 988 TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE---QIESLTEVHRRELNDVI 1044
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
+ ++ L E ++ EKE V E + L +++ K + ++
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEVA----ELKQKILLFGCEKEEMNKEITWLKEE 1100
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-----ERIGPQT 551
D L L+ ++ + +D TKL+ + L L E Q
Sbjct: 1101 GVKQD-----TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQE 1155
Query: 552 KVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVALREGGAQADPEELQ 599
+++ L + +K +++ +L+ EE + LK + + + + L+
Sbjct: 1156 QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Score = 42.3 bits (95), Expect = 0.005
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 19/251 (7%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHK--DLKAN---WDK 182
+E+ SL E H+R+ V + + E KE + +LK +
Sbjct: 1026 KEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1085
Query: 183 EKTDLHKQIADLKDKLLEANVSN---KDQISEMKKDMDELLQALEGAQSEVEMLK----K 235
EK +++K+I LK++ ++ + + ++Q+ + ++ L Q ++ +E L+ K
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1145
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS-KTAQKRLCN 294
L + T EQ +LK E+ + ++TSKLK + E S K +S K+ + +
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Query: 295 MAELEKEVT-RLR---ANERSLRDAICNKL--LLEEQVHQLTSRVEALQPVQLELHEAKV 348
+L +E+ +L +L +A N+L + + + + SR+ Q ++ EA +
Sbjct: 1206 FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1265
Query: 349 KLSSVESQLES 359
+ S+LE+
Sbjct: 1266 IKTCTVSELEA 1276
Score = 39.1 bits (87), Expect = 0.046
Identities = 49/257 (19%), Positives = 106/257 (41%), Gaps = 20/257 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
K L+I L + + + ++N + F+ K + + + E+ S++E
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETEL 1520
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+D E + L N++++K HK++ E +++
Sbjct: 1521 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRV 1580
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKEL----VKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
E ++ + L + ++E+E KKEL + S+ E+ L+++LE ++
Sbjct: 1581 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES------A 1634
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ 325
+KL EL+ + + + +K+L + E EKE + E L + E +
Sbjct: 1635 AKLAELKRKAEQ------KIAAIKKQLLSQME-EKEEQYKKGTESHLSELNTKLQERERE 1687
Query: 326 VHQLTSRVEALQPVQLE 342
VH L ++++++ Q E
Sbjct: 1688 VHILEEKLKSVESSQSE 1704
>AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.19 protein.
Length = 820
Score = 53.2 bits (122), Expect = 3e-06
Identities = 102/555 (18%), Positives = 227/555 (40%), Gaps = 48/555 (8%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEE--EKASLIEQHKRDE--RAVSDMEDXXXX 154
A K+++ KL++ V+ Q + ++M+ +E EK +E+ + + E+
Sbjct: 172 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 231
Query: 155 XXXXXXXXKDEFNTAAKEHKDLK-ANWDKE-KTDLHKQIADLK--DKLLEANVSNKDQIS 210
K+ + AK++ + A+ +E K +H++ +K ++LLEA +
Sbjct: 232 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 291
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-----------EQCTQLKNQLEKQNF 259
+ +D+ + ++AL+ V++ K + + TS+ EQ +K LE++
Sbjct: 292 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 351
Query: 260 EFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ L++L+ E +S K Q ++ K + ++ E+ L+ E L+
Sbjct: 352 DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL--- 408
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALR 376
+ +L+E+ L+S+ + LQ VQ E K ++ ++ Q S+ H ++
Sbjct: 409 EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISERE 468
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEE----VATLKYERDKATGKLNDLTTVRKNQE 432
+ L E+ + L K+N + R+ Q
Sbjct: 469 KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQV 528
Query: 433 SLIHRLQKRLL------LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ- 485
+ K +L + SY + L +EK+ + G G+ V +L ++++
Sbjct: 529 EAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEA 588
Query: 486 ------LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDL 539
L+ + Y+ ++A + K S+ E +W+ + + + + + ++++
Sbjct: 589 DEMHTLLQLECEKYKSVLAETE-GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTS 647
Query: 540 LTASLERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ--EEIKKLKVALREGGAQADPE 596
LER+ + K + + ++ K E+E + E+++LK L E + D
Sbjct: 648 SEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS 707
Query: 597 ELQQMRQQLENSRIK 611
+ +RQ E + +K
Sbjct: 708 YSEAVRQNEELNLLK 722
Score = 32.3 bits (70), Expect = 5.3
Identities = 38/176 (21%), Positives = 82/176 (46%), Gaps = 14/176 (7%)
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
+LHK IA+ KDK ++ +D ++ + + + L+ Q+ +LK E+ K + A
Sbjct: 67 ELHKVIAE-KDKQIK---QTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 122
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN--MAELEKEVT 303
+ ++LEK K++ LE + + +K + ++ N L+ EV
Sbjct: 123 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH----EISNKMEEFKILNDQNKALKSEVQ 178
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
+L ++L NK ++E+ + + E L+ V+ L +++++ E +L +
Sbjct: 179 KL----QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNA 230
Score = 31.5 bits (68), Expect = 9.2
Identities = 28/190 (14%), Positives = 75/190 (39%), Gaps = 3/190 (1%)
Query: 180 WDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
W + + HK I ++ + +++ KD++ L + E + E+E + E
Sbjct: 627 WKVKVDESHKTIKQMQSSFTSSE-QELERLRSENKDIENLRREREHLEMELEKAEMERST 685
Query: 240 QTSRAEQCTQLKNQLEKQ-NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-E 297
+ + L +L+K+ + + + + +EL + + T+ +T Q +A +
Sbjct: 686 YVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGD 745
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
L K L + + A + ++E + + + + L++ +L + +
Sbjct: 746 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 805
Query: 358 ESWMSAARAH 367
++ + H
Sbjct: 806 NQQLTKEKEH 815
>AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 protein.
Length = 1357
Score = 53.2 bits (122), Expect = 3e-06
Identities = 102/555 (18%), Positives = 227/555 (40%), Gaps = 48/555 (8%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEE--EKASLIEQHKRDE--RAVSDMEDXXXX 154
A K+++ KL++ V+ Q + ++M+ +E EK +E+ + + E+
Sbjct: 709 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 768
Query: 155 XXXXXXXXKDEFNTAAKEHKDLK-ANWDKE-KTDLHKQIADLK--DKLLEANVSNKDQIS 210
K+ + AK++ + A+ +E K +H++ +K ++LLEA +
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 828
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-----------EQCTQLKNQLEKQNF 259
+ +D+ + ++AL+ V++ K + + TS+ EQ +K LE++
Sbjct: 829 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 888
Query: 260 EFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ L++L+ E +S K Q ++ K + ++ E+ L+ E L+
Sbjct: 889 DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL--- 945
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALR 376
+ +L+E+ L+S+ + LQ VQ E K ++ ++ Q S+ H ++
Sbjct: 946 EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISERE 1005
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEE----VATLKYERDKATGKLNDLTTVRKNQE 432
+ L E+ + L K+N + R+ Q
Sbjct: 1006 KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQV 1065
Query: 433 SLIHRLQKRLL------LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ- 485
+ K +L + SY + L +EK+ + G G+ V +L ++++
Sbjct: 1066 EAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEA 1125
Query: 486 ------LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDL 539
L+ + Y+ ++A + K S+ E +W+ + + + + + ++++
Sbjct: 1126 DEMHTLLQLECEKYKSVLAETE-GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTS 1184
Query: 540 LTASLERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ--EEIKKLKVALREGGAQADPE 596
LER+ + K + + ++ K E+E + E+++LK L E + D
Sbjct: 1185 SEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS 1244
Query: 597 ELQQMRQQLENSRIK 611
+ +RQ E + +K
Sbjct: 1245 YSEAVRQNEELNLLK 1259
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/513 (18%), Positives = 220/513 (42%), Gaps = 45/513 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 422 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 481
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 482 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 532
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 533 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 589
Query: 362 SAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKA 417
S A SA L + L + LT EE+ ++
Sbjct: 590 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA---G 474
++ L + Q + H L+K V + D R + + E++ + EE
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM--EEFKILND 705
Query: 475 SVALLSARVQQLEK--SLQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDV 530
L + VQ+L+ S Q +D++ + K L+++ + + ++
Sbjct: 706 QNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 765
Query: 531 TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK---ELEAAQE--EIKKLKVA 585
+RT+ LT ++ + + + E +K I + ++++ +E E + LKVA
Sbjct: 766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 825
Query: 586 LREGGAQADPEELQQMRQQLENSRI-KLKRYSI 617
+E Q +E++ +++++ N ++ K ++ SI
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
Score = 31.5 bits (68), Expect = 9.2
Identities = 28/190 (14%), Positives = 75/190 (39%), Gaps = 3/190 (1%)
Query: 180 WDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
W + + HK I ++ + +++ KD++ L + E + E+E + E
Sbjct: 1164 WKVKVDESHKTIKQMQSSFTSSE-QELERLRSENKDIENLRREREHLEMELEKAEMERST 1222
Query: 240 QTSRAEQCTQLKNQLEKQ-NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-E 297
+ + L +L+K+ + + + + +EL + + T+ +T Q +A +
Sbjct: 1223 YVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGD 1282
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
L K L + + A + ++E + + + + L++ +L + +
Sbjct: 1283 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1342
Query: 358 ESWMSAARAH 367
++ + H
Sbjct: 1343 NQQLTKEKEH 1352
>AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ43937 fis, clone TESTI4013924. ).
Length = 623
Score = 53.2 bits (122), Expect = 3e-06
Identities = 88/441 (19%), Positives = 184/441 (41%), Gaps = 26/441 (5%)
Query: 166 FNTAAKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
F+ A E +++K DKEK L Q+ +L +L E + Q+ + K++
Sbjct: 10 FSAMASELEEVKRCMERKDKEKAHLASQVENLTREL-ENGEKQQLQMLDRLKEIQNHFDT 68
Query: 223 LEGAQSEVEMLKKELVKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYE-RDSYKD 280
E + ++ EL + A +Q + ++L++ ++ + ++L+ + ++S +
Sbjct: 69 CEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQ 128
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
W+ + K ++ L +E E+T N + L++ K L + Q+ + + L V
Sbjct: 129 WKLKHKKLERALEKQSETVDELTG--KNNQILKEKDELKTQLYAALQQIENLRKELNDVL 186
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ + +L S E +L S +E +L D +
Sbjct: 187 TKRALQEEELHSKEEKLRDIKSHQADLELEVKNSL-DTIHRLESELKKQSKIQSQMKVEK 245
Query: 401 XHLTEEVATLK--YERDKA-----TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYR 453
HL EE+A LK +DKA + DL+ +R + + + ++ V ++
Sbjct: 246 AHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLT 305
Query: 454 QQLDCYEKE---LTVTLCGEEGAGSVAL--LSARVQQLE-KSLQGYRDLIAAHDPHAHSK 507
Q ++E + L E L L++ +Q ++ K Q ++L+ H S+
Sbjct: 306 AQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELM-KHFKKEKSE 364
Query: 508 A---LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEA 564
A + +L+ E + A+ R + KL++Q D LT L + + K L L +
Sbjct: 365 AENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQ 424
Query: 565 QKQISKELEAAQEEIKKLKVA 585
++ K + +E +++++ A
Sbjct: 425 LEEREKHISIEEEHLRRMEEA 445
Score = 43.2 bits (97), Expect = 0.003
Identities = 108/539 (20%), Positives = 202/539 (37%), Gaps = 39/539 (7%)
Query: 27 KDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKRLRRDSSGNGTT-- 84
KDK A + T+ ++ G L R I + D +R D + T
Sbjct: 27 KDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRH 86
Query: 85 APPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA 144
A + + +R +L ++A + E R R+++++ +E +HK+ ERA
Sbjct: 87 AEDATKQAERYLSELQQSEALKEEAEKR-------REDLKLKAQESIRQWKLKHKKLERA 139
Query: 145 V---SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDL-------HKQIADL 194
+ S+ D KDE T N KE D+ +++
Sbjct: 140 LEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSK 199
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
++KL + D E+K +D + + + + ++ + V++ E+ +LK
Sbjct: 200 EEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQ 259
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
+ + ++ +K+L R + + + A+K + + +L + ++ +
Sbjct: 260 AQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAV--LKDLSDLTAQAKSRDEETA- 316
Query: 315 AICNKLLLEEQVHQ--LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESA 372
I +L LE VHQ L +LQ V+ + HE ++ + + S A H + +
Sbjct: 317 TIITQLKLERDVHQRELKDLTSSLQSVKTK-HEQNIQ--ELMKHFKKEKSEAENH-IRTL 372
Query: 373 GALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQE 432
A ++LE LTEE+ + E K K L + +E
Sbjct: 373 KA--ESLEEK-NMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEERE 429
Query: 433 SLIHRLQKRLLLVTRERDSYRQQLDCY--EKELTVTLCGEEGAGSVALLSARVQQLEKSL 490
I ++ L + R + QL C E+E + + G+E + S + K
Sbjct: 430 KHISIEEEHLRRMEEARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVF 489
Query: 491 QGYRDLIAAHDPH---AHSKA-LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLE 545
D+ +DPH A SK L+ L E+ + R + R Q LT + E
Sbjct: 490 SSGPDI--HYDPHRWLAESKTKLQWLCEELKERENREKNLRHQLMLCRQQLRNLTENKE 546
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 53.2 bits (122), Expect = 3e-06
Identities = 117/551 (21%), Positives = 236/551 (42%), Gaps = 62/551 (11%)
Query: 91 ETKRLKIDLIAAKAQ-ITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDME 149
ETKR + + K + I +L SR+ T +E++ E+ + + E+ E+A+S +
Sbjct: 399 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL---EKALSTAQ 455
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
++ T K ++ + + +E + + +++ D+ K S+++QI
Sbjct: 456 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKK------SSEEQI 509
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF-------- 261
++++K L E A+ E E+ KK QT E Q+K LEK E+
Sbjct: 510 AKLQK-----LHEKELARKEQELTKK---LQTREREFQEQMKVALEKSQSEYLKISQEKE 561
Query: 262 QQVTSKLKELEYER--------DSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANERSL 312
QQ + L+ELE ++ + +D Q +++T + R+ + + LEK + + + L
Sbjct: 562 QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 621
Query: 313 R---DAICNKLLLE--EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAH 367
+A NK E V + + +E+L+ Q L K+++ + Q E +
Sbjct: 622 AVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE 681
Query: 368 GVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV 427
E L+D E +++ E KA KL + +V
Sbjct: 682 -QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 740
Query: 428 RKNQ-ESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
K+Q + + L+ ++ +++ ++QQ+D KE V++ E A L ++ QL
Sbjct: 741 LKDQTDKMKQELEAKM---DEQKNHHQQQVDSIIKEHEVSIQRTEKA-----LKDQINQL 792
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA--------EGARRDVTKLRTQRD 538
E L+ + H H + + R+E + A + A + TK +
Sbjct: 793 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK-AYEEQ 851
Query: 539 LLTASLERIGPQTKVLHLTNNPA-AEAQKQ-ISKELEAAQEEIKKLKVALREGGAQADPE 596
L + + +T+ + LT A EAQK+ + EL+A + +++ L L + ++ + +
Sbjct: 852 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEME-Q 910
Query: 597 ELQQMRQQLEN 607
+++ + Q E+
Sbjct: 911 KVKSLTQVYES 921
Score = 49.2 bits (112), Expect = 4e-05
Identities = 95/406 (23%), Positives = 184/406 (45%), Gaps = 44/406 (10%)
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
K ++ L Q ++ ++ ++ K+ + S EQCT L + EK+ + +Q+ +L+ELE
Sbjct: 310 KTLETLQQRVKRQENLLKRCKETI---QSHKEQCTLLTS--EKEALQ-EQLDERLQELEK 363
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTS 331
+D + +T+ T + N+ E LE++ + A +R + + + K EE++ QL S
Sbjct: 364 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK---EEEIAQLRS 420
Query: 332 RVEALQPVQLELHEAKVKLS-SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXX 390
R++ + EL E K K + +LE +S A+ E+ L+ ++ +
Sbjct: 421 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ-KTEEARRKLKAEMDEQIKTIEKTS 479
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK-RLLLVTRER 449
EE +L+ E + ++ D+ ++K+ E I +LQK + R+
Sbjct: 480 -------------EEERISLQQELSRVKQEVVDV--MKKSSEEQIAKLQKLHEKELARKE 524
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKA 508
++L E+E + VAL ++ + L+ S + ++ +A + KA
Sbjct: 525 QELTKKLQTREREFQEQM-------KVALEKSQSEYLKISQEKEQQESLALEELELQKKA 577
Query: 509 -LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
L N++ ++EAE R + +L + L SL+ Q+K L + AE K
Sbjct: 578 ILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSK--DLAVHLEAEKNKH 632
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+KE+ E+ K +L+ E+LQ ++QQ + KL+
Sbjct: 633 -NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLR 677
Score = 42.7 bits (96), Expect = 0.004
Identities = 94/530 (17%), Positives = 209/530 (39%), Gaps = 50/530 (9%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L+ +L K Q K++ + + +K +++ S+I++H E ++ E
Sbjct: 733 KLEEELSVLKDQTDKMKQELEAKMDEQKNHH---QQQVDSIIKEH---EVSIQRTEKALK 786
Query: 154 XXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
E + KEH+ +L+A+ + + +L + A L D + +Q
Sbjct: 787 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQT 845
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLK----------NQLEKQN 258
++ + +L Q L ++E +L K++ + + + + CT+L QLEKQN
Sbjct: 846 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 905
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
E +Q L ++ YE + Q +T Q + E E + ++R ++ + +
Sbjct: 906 SEMEQKVKSLTQV-YESKLEDGNKEQEQTKQ----ILVEKENMILQMREGQKKEIEILTQ 960
Query: 319 KL-LLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
KL E+ +H L E + + ++ + K K ++ L+ + A +
Sbjct: 961 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE--N 1018
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
ALE + +++ V+ L+ + + ++ LT V + + + +
Sbjct: 1019 TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE---QIESLTEVHRRELNDVI 1075
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
+ ++ L E ++ EKE V E + L +++ K + ++
Sbjct: 1076 SIWEKKLNQQAEELQEIHEIQLQEKEQEVA----ELKQKILLFGCEKEEMNKEITWLKEE 1131
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-----ERIGPQT 551
D L L+ ++ + +D TKL+ + L L E Q
Sbjct: 1132 GVKQD-----TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQE 1186
Query: 552 KVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVALREGGAQADPEELQ 599
+++ L + +K +++ +L+ EE + LK + + + + L+
Sbjct: 1187 QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1236
Score = 42.3 bits (95), Expect = 0.005
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 19/251 (7%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHK--DLKAN---WDK 182
+E+ SL E H+R+ V + + E KE + +LK +
Sbjct: 1057 KEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1116
Query: 183 EKTDLHKQIADLKDKLLEANVSN---KDQISEMKKDMDELLQALEGAQSEVEMLK----K 235
EK +++K+I LK++ ++ + + ++Q+ + ++ L Q ++ +E L+ K
Sbjct: 1117 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1176
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS-KTAQKRLCN 294
L + T EQ +LK E+ + ++TSKLK + E S K +S K+ + +
Sbjct: 1177 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1236
Query: 295 MAELEKEVT-RLR---ANERSLRDAICNKL--LLEEQVHQLTSRVEALQPVQLELHEAKV 348
+L +E+ +L +L +A N+L + + + + SR+ Q ++ EA +
Sbjct: 1237 FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1296
Query: 349 KLSSVESQLES 359
+ S+LE+
Sbjct: 1297 IKTCTVSELEA 1307
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 52.8 bits (121), Expect = 3e-06
Identities = 82/398 (20%), Positives = 160/398 (40%), Gaps = 34/398 (8%)
Query: 219 LLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSY 278
L AL+ A+ + ++L+++ ++T E +L+ L K N E Q +K YE D+
Sbjct: 5 LAHALQSARHDCDLLREQYEEET---EAKAELQRVLSKANSEVAQWRTK-----YETDAI 56
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
+ + + +K + E E+ V + A C+ L E+ H+L + +E L
Sbjct: 57 QRTEELEEAKKKLAQRLQEAEEAVEAVNAK--------CSSL--EKTKHRLQNEIEDLMV 106
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXX 398
+ A L + + ++ + ES L + + A
Sbjct: 107 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 166
Query: 399 XXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDC 458
HL T K E +++DLT + IH L+K V ++ ++ + +L
Sbjct: 167 SLEHLE----TFKRENKNLQEEISDLTEQLGSSGKTIHELEK----VRKQLEAEKMELQS 218
Query: 459 YEKELTVTLCGEEGAGSVALLSAR--VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEV 516
+E +L EEG A L ++E+ L +D H + ++SL+ +
Sbjct: 219 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSL 277
Query: 517 ---TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQT-KVLHLTNNPAAEAQKQISKEL 572
TR R EA ++ + + ++ + R+ + K + + + Q Q+ +
Sbjct: 278 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 337
Query: 573 EAAQEEIKKLKVALREGG-AQADPEELQQMRQQLENSR 609
A + + + + R QA+ EEL+ + +Q E SR
Sbjct: 338 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 375
>DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein.
Length = 805
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 429 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 486
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 487 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 539
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 540 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 596
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 597 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 656
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 657 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 692
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 434 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 486
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 487 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 546
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 547 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 606
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 607 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 657
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 658 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 699
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 260 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 319
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 320 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 374
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 375 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 422
>DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1
protein.
Length = 824
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 448 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 505
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 506 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 558
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 559 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 615
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 616 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 675
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 676 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 711
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 453 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 505
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 506 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 565
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 566 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 625
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 626 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 676
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 677 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 718
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 279 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 338
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 339 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 393
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 394 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 441
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 52.8 bits (121), Expect = 3e-06
Identities = 87/455 (19%), Positives = 183/455 (40%), Gaps = 27/455 (5%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQ----ALEGA 226
K+H + + +L+K++ +D+L+ +V+ K+ + ++ K+M + ++ E A
Sbjct: 245 KQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEA 304
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ----NFEFQQVTSKLKELEYERDSYKDWQ 282
+ E E + + V+ + + K LEK+ N E ++ T+K+K+L E+
Sbjct: 305 RQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLY 364
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ RL + E++K + ++ ++ A NKL E H+ T + L+ +
Sbjct: 365 ETKEGETTRL--IREIDKLKEDINSHVIKVKWA-QNKLKAEMDSHKETK--DKLKETTTK 419
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
L +AK + + + + + + L L G
Sbjct: 420 LTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHA 479
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLLLVTRERDSYRQQLDC 458
+E+ LK + +L L T K E R L K ++ R++ + LD
Sbjct: 480 KIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDK 539
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ + + G + L V+ L + DL D K L R
Sbjct: 540 VKTADQLQEQLQRGKQEIENLKEEVESLNSLI---NDL--QKDIEGSRKRESELLLFTER 594
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+ + + L++Q D ++ S ++ Q + + TN + ++ KE E +EE
Sbjct: 595 LTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTN---INLESRLLKEEELRKEE 651
Query: 579 IKKL--KVALREGGAQADPEELQQMRQQLENSRIK 611
++ L ++A R+ +A ++++++ +L R K
Sbjct: 652 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/512 (18%), Positives = 205/512 (40%), Gaps = 42/512 (8%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
LE + +R+EM FE S + + V +M+D +E
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSA---KTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQ 227
K + L ++E+ ++ K ++ V K+++S + +EL + G Q
Sbjct: 407 MLKSNGALSTE-EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQ 465
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKT 287
+E+ +K+EL ++ + + L+ +LE +F ++ L+ +S T
Sbjct: 466 AEIGQVKQELSRKDT---ELLALQTKLETLTNQFSDSKQHIEVLK-----------ESLT 511
Query: 288 AQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELHE 345
A+++ + + E + RLR E ++ + NK +++ + ++ + ++ L
Sbjct: 512 AKEQRAAILQTEVDALRLRLEE---KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV 568
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTE 405
+ K++ ++ ++E+ R + +L++ ++S
Sbjct: 569 KERKVNVLQKKIENLQEQLR-DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 406 EVATLKYERDK-ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ LK +RD+ K ++ +K+ + L +K LL + LD E +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDL---KEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 465 VTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKA-------LESLRNEV 516
+ G + + L A Q+ E+ L+ L AH+ ++A ++ L E+
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 517 TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
TR+++E+ A+ +V +L L E+ K+ L + K+++ Q
Sbjct: 745 TRYKDESSKAQAEVDRL--LEILKEVENEKNDKDKKIAEL-ERQVKDQNKKVANLKHKEQ 801
Query: 577 EEIKKLKVALREGGAQADPEELQQMRQQLENS 608
E KK L E A+ + L QQL++S
Sbjct: 802 VEKKKSAQMLEE--ARRREDNLNDSSQQLQDS 831
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 20/252 (7%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-EQCT 248
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K++ + + +Q
Sbjct: 732 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 791
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEKEVTR 304
++ N K+ E ++ L+E D+ D Q Q +K R+ + E +E +
Sbjct: 792 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 851
Query: 305 LRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL---ESW 360
+ A E L + E+QV +L + A++ V+ EL K KLSS + L E+
Sbjct: 852 ITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAEKETH 908
Query: 361 MSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
++ RA H E ++AL +A+ EEVA LK E+D+
Sbjct: 909 LTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKREKDR 967
Query: 417 ATGKLNDLTTVR 428
+L T R
Sbjct: 968 LVQQLKQQTQNR 979
Score = 41.9 bits (94), Expect = 0.006
Identities = 83/387 (21%), Positives = 148/387 (38%), Gaps = 39/387 (10%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRDERAVSDME 149
K L+ D +T LE + + TI KE + E EK I+ +K+D + D++
Sbjct: 602 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD---LKDLK 658
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKDQ 208
+ K+ KEH A+ +K D + K LE A K++
Sbjct: 659 EKVSLLQGDLSE-KEASLLDLKEHASSLASSGLKK--------DSRLKTLEIALEQKKEE 709
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
+M+ + + +A A++ EM + ++ R + T+ K++ K E ++ L
Sbjct: 710 CLKMESQLKKAHEAALEARASPEM--SDRIQHLER--EITRYKDESSKAQAEVDRLLEIL 765
Query: 269 KELEYERDS----YKDWQTQSKTAQKRLCNMA---ELEKEVTRLRANERSLRDAICN--K 319
KE+E E++ + + Q K K++ N+ ++EK+ + E R+ N
Sbjct: 766 KEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSS 825
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
L++ + + R+E L+ E + + V +Q ES + A E A+
Sbjct: 826 QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVK 885
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLT----------EEVATLKYERDKATGKLNDLTTVRK 429
+ HLT EEV +K E A D
Sbjct: 886 QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 945
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 946 ELSSSKKKTQEEVAALKREKDRLVQQL 972
Score = 41.1 bits (92), Expect = 0.011
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 13 VLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
+LE + V N + KDK A D + + L + K+KS+ + +
Sbjct: 761 LLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN-LKHKEQVEKKKSA-----QMLEEA 814
Query: 73 RLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKA 132
R R D+ + + ++L+ L +I +LE + I E +++ +E++
Sbjct: 815 RRREDNLNDSS---------QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEES 865
Query: 133 SLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIA 192
+ K+ E + ME + A++ L N E+ +++
Sbjct: 866 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVL 924
Query: 193 DLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN 252
++K + L A +S KD + EL + + Q EV LK+E + + +Q TQ +
Sbjct: 925 EMKQEALLAAISEKDANIALL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980
Query: 253 QLEKQNFE 260
+L N+E
Sbjct: 981 KLMADNYE 988
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/512 (18%), Positives = 205/512 (40%), Gaps = 42/512 (8%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
LE + +R+EM FE S + + V +M+D +E
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSA---KTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQ 227
K + L ++E+ ++ K ++ V K+++S + +EL + G Q
Sbjct: 407 MLKSNGALSTE-EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQ 465
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKT 287
+E+ +K+EL ++ + + L+ +LE +F ++ L+ +S T
Sbjct: 466 AEIGQVKQELSRKDT---ELLALQTKLETLTNQFSDSKQHIEVLK-----------ESLT 511
Query: 288 AQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELHE 345
A+++ + + E + RLR E ++ + NK +++ + ++ + ++ L
Sbjct: 512 AKEQRAAILQTEVDALRLRLEE---KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV 568
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTE 405
+ K++ ++ ++E+ R + +L++ ++S
Sbjct: 569 KERKVNVLQKKIENLQEQLR-DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 406 EVATLKYERDK-ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ LK +RD+ K ++ +K+ + L +K LL + LD E +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDL---KEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 465 VTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKA-------LESLRNEV 516
+ G + + L A Q+ E+ L+ L AH+ ++A ++ L E+
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 517 TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
TR+++E+ A+ +V +L L E+ K+ L + K+++ Q
Sbjct: 745 TRYKDESSKAQAEVDRL--LEILKEVENEKNDKDKKIAEL-ERQVKDQNKKVANLKHKEQ 801
Query: 577 EEIKKLKVALREGGAQADPEELQQMRQQLENS 608
E KK L E A+ + L QQL++S
Sbjct: 802 VEKKKSAQMLEE--ARRREDNLNDSSQQLQDS 831
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 20/252 (7%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-EQCT 248
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K++ + + +Q
Sbjct: 732 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 791
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEKEVTR 304
++ N K+ E ++ L+E D+ D Q Q +K R+ + E +E +
Sbjct: 792 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 851
Query: 305 LRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL---ESW 360
+ A E L + E+QV +L + A++ V+ EL K KLSS + L E+
Sbjct: 852 ITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAEKETH 908
Query: 361 MSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
++ RA H E ++AL +A+ EEVA LK E+D+
Sbjct: 909 LTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKREKDR 967
Query: 417 ATGKLNDLTTVR 428
+L T R
Sbjct: 968 LVQQLKQQTQNR 979
Score = 41.9 bits (94), Expect = 0.006
Identities = 83/387 (21%), Positives = 148/387 (38%), Gaps = 39/387 (10%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRDERAVSDME 149
K L+ D +T LE + + TI KE + E EK I+ +K+D + D++
Sbjct: 602 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD---LKDLK 658
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKDQ 208
+ K+ KEH A+ +K D + K LE A K++
Sbjct: 659 EKVSLLQGDLSE-KEASLLDLKEHASSLASSGLKK--------DSRLKTLEIALEQKKEE 709
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
+M+ + + +A A++ EM + ++ R + T+ K++ K E ++ L
Sbjct: 710 CLKMESQLKKAHEAALEARASPEM--SDRIQHLER--EITRYKDESSKAQAEVDRLLEIL 765
Query: 269 KELEYERDS----YKDWQTQSKTAQKRLCNMA---ELEKEVTRLRANERSLRDAICN--K 319
KE+E E++ + + Q K K++ N+ ++EK+ + E R+ N
Sbjct: 766 KEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSS 825
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
L++ + + R+E L+ E + + V +Q ES + A E A+
Sbjct: 826 QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVK 885
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLT----------EEVATLKYERDKATGKLNDLTTVRK 429
+ HLT EEV +K E A D
Sbjct: 886 QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 945
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 946 ELSSSKKKTQEEVAALKREKDRLVQQL 972
Score = 41.1 bits (92), Expect = 0.011
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 13 VLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
+LE + V N + KDK A D + + L + K+KS+ + +
Sbjct: 761 LLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN-LKHKEQVEKKKSA-----QMLEEA 814
Query: 73 RLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKA 132
R R D+ + + ++L+ L +I +LE + I E +++ +E++
Sbjct: 815 RRREDNLNDSS---------QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEES 865
Query: 133 SLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIA 192
+ K+ E + ME + A++ L N E+ +++
Sbjct: 866 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVL 924
Query: 193 DLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN 252
++K + L A +S KD + EL + + Q EV LK+E + + +Q TQ +
Sbjct: 925 EMKQEALLAAISEKDANIALL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980
Query: 253 QLEKQNFE 260
+L N+E
Sbjct: 981 KLMADNYE 988
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 52.8 bits (121), Expect = 3e-06
Identities = 115/550 (20%), Positives = 224/550 (40%), Gaps = 47/550 (8%)
Query: 105 QITKLESRVNHQHTIR-KEMQILFEEEKASLIEQHKRDERAVSDM---EDXXXXXXXXXX 160
+I L+++ N + KEM+ L + + E+ E S + ED
Sbjct: 627 EIENLQNQQNSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 686
Query: 161 XXKDEFNTAAKEHKDLKANWDKEKT---DLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
E KE + L+A +++ + Q ++KLL+ + K SE K +M
Sbjct: 687 NKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKLLDLDALRKAS-SEGKSEMK 745
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCT------QLK-NQLEKQNFEFQQVTSKL-K 269
+L Q LE A+ +++ L+ E ++S+A T +LK L++ E QV L K
Sbjct: 746 KLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK 805
Query: 270 ELEYERDSYKDWQTQS----KTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEE 324
EL+ ++ + + ++ ++ Q+ + + + E++ L ++ LR+ + + + E
Sbjct: 806 ELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFRE 865
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
+ + ++A + ++ ++ E SQL R L+ L A
Sbjct: 866 KDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKA-N 923
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT--GKLNDLTTVRKNQESLIHRLQKRL 442
+++ A K+E +K KL+DL + + L+ R
Sbjct: 924 ENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARY 983
Query: 443 LLVTRE-RDSYRQQLDCYEKELTVT---LCG--EEGAGSVALLSARVQQLEKS--LQGYR 494
T E + + + L +K L T L G EE +G + L +Q +K+ Q
Sbjct: 984 ERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAE 1043
Query: 495 DLIAAHDPHAHSK-----ALESLRNEVTRWREEAEGAR----RDVTKLRTQRDLLTASLE 545
D + + K +LE + + + E + + ++V +L ++LLT +
Sbjct: 1044 DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQ 1103
Query: 546 RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL-REGGAQADPEELQQMRQQ 604
++ K + AA Q S++L A QEE KL L R ++L++ R
Sbjct: 1104 KMEEFRKEIETLKQAAA----QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV 1159
Query: 605 LENSRIKLKR 614
L N +++K+
Sbjct: 1160 LNNQLLEMKK 1169
Score = 46.8 bits (106), Expect = 2e-04
Identities = 92/551 (16%), Positives = 231/551 (41%), Gaps = 55/551 (9%)
Query: 103 KAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
K ++ L+ RV + + ++++ EK+ ++E K V ++ +
Sbjct: 435 KRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 494
Query: 163 KDEFNTAA-KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI-------SEMKK 214
+ + + +E L+ + +TD ++I LK+ +++ +I ++ K
Sbjct: 495 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 215 DMDELLQALEGAQSE----VEMLKKELVKQTSRAEQC-TQLKNQLEK----QNFEFQQVT 265
+ + L LE A E + + K +L + +Q +LK K + EF ++
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELK 614
Query: 266 SKLKEL----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL 321
++++++ ++E ++ ++ Q + A + M L ++ ++ + + +AI +KL
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQNSERAAHAK--EMEALRAKLMKVIKEKENSLEAIRSKLD 672
Query: 322 LEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ---LESWMSAARAHGVESAGALR 376
E H ++ + LQ ++++ E +V + Q ++++ S +A E
Sbjct: 673 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKA--TEEKLLDL 730
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
DAL A +++ L+ E++ + K + +T + +E +
Sbjct: 731 DALRKASSEGKSEMKKLRQQLEAA---EKQIKHLEIEKNAESSKASSITRELQGRELKLT 787
Query: 437 RLQKRLLLVTRERDSYRQQL--------DCYEKELTVTLCGEEGAGSVALLSARVQQLEK 488
LQ+ L V++ +++ ++L + E+ ++V +E + + L
Sbjct: 788 NLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 847
Query: 489 SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG 548
L+ R+ +A D A + + ++ + +E+ E ++ K+ ++ L ++
Sbjct: 848 DLEKLRENLA--DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN---SSQLTKMN 902
Query: 549 PQTKVLHLTNNPAAEAQKQISKELEAA---QEEIKKLKVALREG---GAQADPEELQQMR 602
+ L L E Q +++K E A Q+ I+ + V + A+ EE +++
Sbjct: 903 DE---LRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELE 959
Query: 603 QQLENSRIKLK 613
++L + K++
Sbjct: 960 RKLSDLEKKME 970
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/222 (20%), Positives = 100/222 (45%), Gaps = 22/222 (9%)
Query: 98 DLIAAKAQITKLESRVNH----QHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L + ++T L+ ++ + T+ KE+QIL +E+ A E+ +R++ + +
Sbjct: 778 ELQGRELKLTNLQENLSEVSQVKETLEKELQIL-KEKFAEASEEAVSVQRSMQETVNKLH 836
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL-------LEANVSNK 206
+ + D++A + +EK + +Q+ K+KL ++ + N
Sbjct: 837 QKEEQFNMLSSDLEKLRENLADMEAKF-REKDEREEQLIKAKEKLENDIAEIMKMSGDNS 895
Query: 207 DQISEM-------KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF 259
Q+++M ++D++EL L A L+K + T +AEQ Q +K
Sbjct: 896 SQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ--EAAKKHEE 953
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
E +++ KL +LE + ++ + + K +R + + + E
Sbjct: 954 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE 995
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 52.8 bits (121), Expect = 3e-06
Identities = 87/455 (19%), Positives = 183/455 (40%), Gaps = 27/455 (5%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQ----ALEGA 226
K+H + + +L+K++ +D+L+ +V+ K+ + ++ K+M + ++ E A
Sbjct: 245 KQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEA 304
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ----NFEFQQVTSKLKELEYERDSYKDWQ 282
+ E E + + V+ + + K LEK+ N E ++ T+K+K+L E+
Sbjct: 305 RQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLY 364
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ RL + E++K + ++ ++ A NKL E H+ T + L+ +
Sbjct: 365 ETKEGETTRL--IREIDKLKEDINSHVIKVKWA-QNKLKAEMDSHKETK--DKLKETTTK 419
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
L +AK + + + + + + L L G
Sbjct: 420 LTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHA 479
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLLLVTRERDSYRQQLDC 458
+E+ LK + +L L T K E R L K ++ R++ + LD
Sbjct: 480 KIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDK 539
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ + + G + L V+ L + DL D K L R
Sbjct: 540 VKTADQLQEQLQRGKQEIENLKEEVESLNSLI---NDL--QKDIEGSRKRESELLLFTER 594
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+ + + L++Q D ++ S ++ Q + + TN + ++ KE E +EE
Sbjct: 595 LTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTN---INLESRLLKEEELRKEE 651
Query: 579 IKKL--KVALREGGAQADPEELQQMRQQLENSRIK 611
++ L ++A R+ +A ++++++ +L R K
Sbjct: 652 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 52.8 bits (121), Expect = 3e-06
Identities = 87/455 (19%), Positives = 183/455 (40%), Gaps = 27/455 (5%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQ----ALEGA 226
K+H + + +L+K++ +D+L+ +V+ K+ + ++ K+M + ++ E A
Sbjct: 351 KQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEA 410
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ----NFEFQQVTSKLKELEYERDSYKDWQ 282
+ E E + + V+ + + K LEK+ N E ++ T+K+K+L E+
Sbjct: 411 RQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLY 470
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ RL + E++K + ++ ++ A NKL E H+ T + L+ +
Sbjct: 471 ETKEGETTRL--IREIDKLKEDINSHVIKVKWA-QNKLKAEMDSHKETK--DKLKETTTK 525
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
L +AK + + + + + + L L G
Sbjct: 526 LTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHA 585
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLLLVTRERDSYRQQLDC 458
+E+ LK + +L L T K E R L K ++ R++ + LD
Sbjct: 586 KIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDK 645
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTR 518
+ + + G + L V+ L + DL D K L R
Sbjct: 646 VKTADQLQEQLQRGKQEIENLKEEVESLNSLI---NDL--QKDIEGSRKRESELLLFTER 700
Query: 519 WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+ + + L++Q D ++ S ++ Q + + TN + ++ KE E +EE
Sbjct: 701 LTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTN---INLESRLLKEEELRKEE 757
Query: 579 IKKL--KVALREGGAQADPEELQQMRQQLENSRIK 611
++ L ++A R+ +A ++++++ +L R K
Sbjct: 758 VQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 792
>BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein.
Length = 829
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 453 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 510
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 511 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 563
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 564 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 620
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 621 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 680
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 681 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 716
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 458 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 510
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 511 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 570
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 571 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 630
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 631 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 681
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 682 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 723
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 284 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 343
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 344 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 398
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 399 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 446
>BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein.
Length = 873
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/513 (18%), Positives = 220/513 (42%), Gaps = 45/513 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 422 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 481
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 482 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 532
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 533 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 589
Query: 362 SAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKA 417
S A SA L + L + LT EE+ ++
Sbjct: 590 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 647
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA---G 474
++ L + Q + H L+K V + D R + + E++ + EE
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM--EEFKILND 705
Query: 475 SVALLSARVQQLEK--SLQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDV 530
L + VQ+L+ S Q +D++ + K L+++ + + ++
Sbjct: 706 QNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 765
Query: 531 TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK---ELEAAQE--EIKKLKVA 585
+RT+ LT ++ + + + E +K I + ++++ +E E + LKVA
Sbjct: 766 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 825
Query: 586 LREGGAQADPEELQQMRQQLENSRI-KLKRYSI 617
+E Q +E++ +++++ N ++ K ++ SI
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 858
>BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 763
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 387 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 444
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 445 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 497
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 498 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 554
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 555 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 614
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 615 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 650
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 392 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 444
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 445 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 504
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 505 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 564
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 565 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 615
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 616 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 657
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 218 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 277
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 278 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 332
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 333 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 380
>AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 805
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 429 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 486
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 487 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 539
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 540 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 596
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 597 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 656
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 657 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 692
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 434 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 486
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 487 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 546
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 547 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 606
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 607 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 657
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 658 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 699
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 260 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 319
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 320 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 374
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 375 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 422
>AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 805
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 429 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 486
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 487 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 539
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 540 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 596
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 597 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 656
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 657 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 692
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 434 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 486
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 487 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 546
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 547 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 606
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 607 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 657
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 658 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 699
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 260 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 319
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 320 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 374
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 375 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 422
>AL445287-5|CAH71068.1| 765|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 765
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 448 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 505
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 506 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 558
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 559 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 615
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 616 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 675
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 676 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 711
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 453 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 505
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 506 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 565
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 566 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 625
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 626 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 676
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 677 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 718
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 279 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 338
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 339 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 393
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 394 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 441
>AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 805
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 429 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 486
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 487 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 539
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 540 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 596
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 597 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 656
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 657 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 692
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 434 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 486
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 487 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 546
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 547 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 606
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 607 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 657
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 658 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 699
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 260 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 319
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 320 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 374
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 375 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 422
>AL359091-22|CAI13505.1| 765|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 765
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/276 (22%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT 241
KEK DL +I L D++ + + +M++D D L++ L +E K E +
Sbjct: 448 KEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLE--NER 505
Query: 242 SRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE 301
+A ++++L + + E QQ+ + +K E D+YK S+ + RL E+ +
Sbjct: 506 LKA-SFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYK-----SQVMKTRL-EADEVAAQ 558
Query: 302 VTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ R + L+D + NK +E Q S++ LQ + L + KL+ + QL+ +
Sbjct: 559 LERCDKENKILKDEM-NK-EIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGY- 615
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
LR +E L+ +V L+ + + + +
Sbjct: 616 ERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQN 675
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ V +E IH+ Q RL TRE + +QL+
Sbjct: 676 IEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLE 711
Score = 52.8 bits (121), Expect = 3e-06
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 27/282 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
L++++I ++T L VN Q T+ ++M+ E++ SL+E+ R S +
Sbjct: 453 LELEIIVLNDRVTDL---VNQQQTLEEKMR----EDRDSLVERLHRQTAEYSAFKLENER 505
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA---NW----DKEKTDLHK---QIADLKDKLLEANVS 204
+D+ N A E + LKA N+ D K+ + K + ++ +L +
Sbjct: 506 LKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKE 565
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
NK EM K+++ + + ++++ L L ++ +C E++N + +
Sbjct: 566 NKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAI 625
Query: 265 TSKLKE-LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLE 323
S L+ +E++ D + + + + +QK +L +V L ER L +
Sbjct: 626 ISDLRSRIEHQGDKLEMAREKHQASQKE---NKQLSLKVDEL---ERKLEATSAQNI--- 676
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
E + + R EA+ QL L E + ++ QLES + AR
Sbjct: 677 EFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDAR 718
Score = 38.7 bits (86), Expect = 0.060
Identities = 36/168 (21%), Positives = 74/168 (44%), Gaps = 6/168 (3%)
Query: 196 DKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
++L+E + +++E + LL L+ EVE L +E+ + ++A+ ++L +E
Sbjct: 279 ERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSME 338
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLR-ANERSLRD 314
Q + KE E R + + Q + AE+E + +L+ ++ RD
Sbjct: 339 SMRGHL-QAQLRSKEAENSRLCMQIKNLERSGNQHK----AEVEAIMEQLKELKQKGDRD 393
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
K + Q + E + + ++L + + ++ S LESW S
Sbjct: 394 KESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRS 441
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 52.8 bits (121), Expect = 3e-06
Identities = 96/512 (18%), Positives = 205/512 (40%), Gaps = 42/512 (8%)
Query: 109 LESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNT 168
LE + +R+EM FE S + + V +M+D +E
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSA---KTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQ 227
K + L ++E+ ++ K ++ V K+++S + +EL + G Q
Sbjct: 407 MLKSNGALSTE-EREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQ 465
Query: 228 SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKT 287
+E+ +K+EL ++ + + L+ +LE +F ++ L+ +S T
Sbjct: 466 AEIGQVKQELSRKDT---ELLALQTKLETLTNQFSDSKQHIEVLK-----------ESLT 511
Query: 288 AQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQPVQLELHE 345
A+++ + + E + RLR E ++ + NK +++ + ++ + ++ L
Sbjct: 512 AKEQRAAILQTEVDALRLRLEE---KETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV 568
Query: 346 AKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTE 405
+ K++ ++ ++E+ R + +L++ ++S
Sbjct: 569 KERKVNVLQKKIENLQEQLR-DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 627
Query: 406 EVATLKYERDK-ATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ LK +RD+ K ++ +K+ + L +K LL + LD E +
Sbjct: 628 TIERLKEQRDRDEREKQEEIDNYKKDLKDL---KEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 465 VTLCGEEGAGSVALLS-ARVQQLEKSLQGYRDLIAAHDPHAHSKA-------LESLRNEV 516
+ G + + L A Q+ E+ L+ L AH+ ++A ++ L E+
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 517 TRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
TR+++E+ A+ +V +L L E+ K+ L + K+++ Q
Sbjct: 745 TRYKDESSKAQAEVDRL--LEILKEVENEKNDKDKKIAEL-ERQVKDQNKKVANLKHKEQ 801
Query: 577 EEIKKLKVALREGGAQADPEELQQMRQQLENS 608
E KK L E A+ + L QQL++S
Sbjct: 802 VEKKKSAQMLEE--ARRREDNLNDSSQQLQDS 831
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 20/252 (7%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-EQCT 248
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K++ + + +Q
Sbjct: 732 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 791
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEKEVTR 304
++ N K+ E ++ L+E D+ D Q Q +K R+ + E +E +
Sbjct: 792 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 851
Query: 305 LRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL---ESW 360
+ A E L + E+QV +L + A++ V+ EL K KLSS + L E+
Sbjct: 852 ITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAEKETH 908
Query: 361 MSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
++ RA H E ++AL +A+ EEVA LK E+D+
Sbjct: 909 LTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKREKDR 967
Query: 417 ATGKLNDLTTVR 428
+L T R
Sbjct: 968 LVQQLKQQTQNR 979
Score = 41.9 bits (94), Expect = 0.006
Identities = 83/387 (21%), Positives = 148/387 (38%), Gaps = 39/387 (10%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRDERAVSDME 149
K L+ D +T LE + + TI KE + E EK I+ +K+D + D++
Sbjct: 602 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKD---LKDLK 658
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKDQ 208
+ K+ KEH A+ +K D + K LE A K++
Sbjct: 659 EKVSLLQGDLSE-KEASLLDLKEHASSLASSGLKK--------DSRLKTLEIALEQKKEE 709
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
+M+ + + +A A++ EM + ++ R + T+ K++ K E ++ L
Sbjct: 710 CLKMESQLKKAHEAALEARASPEM--SDRIQHLER--EITRYKDESSKAQAEVDRLLEIL 765
Query: 269 KELEYERDS----YKDWQTQSKTAQKRLCNMA---ELEKEVTRLRANERSLRDAICN--K 319
KE+E E++ + + Q K K++ N+ ++EK+ + E R+ N
Sbjct: 766 KEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSS 825
Query: 320 LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
L++ + + R+E L+ E + + V +Q ES + A E A+
Sbjct: 826 QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVK 885
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLT----------EEVATLKYERDKATGKLNDLTTVRK 429
+ HLT EEV +K E A D
Sbjct: 886 QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 945
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 946 ELSSSKKKTQEEVAALKREKDRLVQQL 972
Score = 41.1 bits (92), Expect = 0.011
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 13 VLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
+LE + V N + KDK A D + + L + K+KS+ + +
Sbjct: 761 LLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN-LKHKEQVEKKKSA-----QMLEEA 814
Query: 73 RLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKA 132
R R D+ + + ++L+ L +I +LE + I E +++ +E++
Sbjct: 815 RRREDNLNDSS---------QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEES 865
Query: 133 SLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIA 192
+ K+ E + ME + A++ L N E+ +++
Sbjct: 866 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVL 924
Query: 193 DLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN 252
++K + L A +S KD + EL + + Q EV LK+E + + +Q TQ +
Sbjct: 925 EMKQEALLAAISEKDANIALL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980
Query: 253 QLEKQNFE 260
+L N+E
Sbjct: 981 KLMADNYE 988
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 52.8 bits (121), Expect = 3e-06
Identities = 115/522 (22%), Positives = 201/522 (38%), Gaps = 34/522 (6%)
Query: 126 LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDK 182
L + K L + K + D E+ +DE K+ DL+ A +K
Sbjct: 983 LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEK 1042
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE---VEMLKKELVK 239
EK ++ +L +++ + S E K + QAL Q+E V L K ++
Sbjct: 1043 EKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR 1102
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
+ E Q +K + ++ KL+ +L+ ++S D Q K + +
Sbjct: 1103 LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD-AAQDKQQLEEKLKKKDS 1161
Query: 299 EKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRVEALQP----VQLELHEAKVKLSS 352
E LR + L A K + L+ + +L +EA + V+ + EA +L
Sbjct: 1162 ELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEE 1221
Query: 353 VESQLE--SWMSAARAHGVE----SAGALRDAL-ESALGXXXXXXXXXXXXXXXXXHLTE 405
+ +LE SA + G G LR L E+AL L E
Sbjct: 1222 LSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGE 1281
Query: 406 EVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
+V +L+ R K + ++L + + + L + + +Y QL E ++ V
Sbjct: 1282 QVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLS--EAKIKV 1339
Query: 466 TLCGEEGAGSV---ALLSARVQQLEKSLQGYRDLIA--AHDPHAHSKALESLRNEVTRWR 520
+ A + L +L + L+ LI+ + +++LE LR ++
Sbjct: 1340 EELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEES 1399
Query: 521 EEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ-- 576
+ V LR DLL E Q ++ L + AE + SK E +A Q
Sbjct: 1400 KAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRT 1459
Query: 577 EEIK--KLKVALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
EE++ K K+ALR A+ E LE ++++L+ S
Sbjct: 1460 EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTES 1501
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/296 (23%), Positives = 132/296 (44%), Gaps = 21/296 (7%)
Query: 91 ETKRLKIDLIAAKAQIT-KLESRVNHQHTIRKEMQILFEEEKASL-IEQHKRDE--RAVS 146
+T R++++L KA++ KL + +R+ Q E +ASL E R+E R
Sbjct: 1633 KTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKK 1692
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
ME + A + ++A +E+ ++ L +L E + +
Sbjct: 1693 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEE-QRLAAELHEQAQALE 1751
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA----EQCTQLKNQLEKQNFEFQ 262
+ S + +++EL ALE + + ++EL++ T R Q T L NQ +K +
Sbjct: 1752 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 1811
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLRANERSLRDAICNKLL 321
Q++ +++E ER ++ + ++K A MA EL+KE ER K
Sbjct: 1812 QLSGEVEEAAQER---REAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-------KKT 1861
Query: 322 LEEQVHQLTSRVEALQPVQLELHEAKV-KLSSVESQLESWMSAARAHGVESAGALR 376
LE+ V +L +R+E + L + +V KL + +LE+ + A + E+ +R
Sbjct: 1862 LEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVR 1917
Score = 50.0 bits (114), Expect = 2e-05
Identities = 85/469 (18%), Positives = 182/469 (38%), Gaps = 31/469 (6%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+++ ++ +E++ E E+A+ K+ A ++E+ +
Sbjct: 1179 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1238
Query: 168 TAAKEHKDL-KANWDKEKTDLHKQ--IADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
K +L + + E+ L + +A L+ K E +Q+ +++ +L +
Sbjct: 1239 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 1298
Query: 225 GAQSEVEMLK---KELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
+ EV+ L + L + + AE+ C ++QL + + +++ +L + +R +
Sbjct: 1299 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 1358
Query: 281 WQTQ-SKTAQKRLCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+ S+ +++ C +++L + L R L + K L V L +
Sbjct: 1359 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDL 1418
Query: 336 LQPVQLELHEAKVKL----SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
L+ E EA+ +L S +++ W S A ++ L +A +
Sbjct: 1419 LREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEE 1478
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
L + L+ E + T +L T+ + L++ L R+ +
Sbjct: 1479 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1538
Query: 452 YRQQLDCYEKE---LTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDLIAA---- 499
+++L+ ++E L L EE ++ L + L++ + D ++
Sbjct: 1539 MQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKS 1598
Query: 500 -HDPHAHSKALESLRNEVTRWREEAEGA-RRDVTK-LRTQRDLLTASLE 545
+ KALE ++E+ EEAEGA + TK LR Q +L E
Sbjct: 1599 IQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1647
Score = 34.3 bits (75), Expect = 1.3
Identities = 64/325 (19%), Positives = 129/325 (39%), Gaps = 20/325 (6%)
Query: 290 KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQL-TSRVEALQPVQLELHEAKV 348
K L A+ E+E+ LRA R LR A+ +++ + S + + L+L +
Sbjct: 913 KPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQD 972
Query: 349 KLSSVESQLESWM-SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEV 407
L+ E + + S + G L + LE L +++
Sbjct: 973 NLADAEERCHLLIKSKVQLEG--KVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1030
Query: 408 ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTL 467
L+ KA + KN + L + + +T+E+ + + + +++ L
Sbjct: 1031 DDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQ---EAHQQALGDLQ 1087
Query: 468 CGEEGAGSVALLSARVQQ----LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEA 523
E+ ++ R++Q LE SL+ + L + +A L ++ +E
Sbjct: 1088 AEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTE-----RAKRKLEGDLKLTQESV 1142
Query: 524 EGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
A +D +L + + L ++ + + L A+ QK+I KEL+A EE+++
Sbjct: 1143 ADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLL---GAQMQKKI-KELQARAEELEEEL 1198
Query: 584 VALREGGAQADPEELQQMRQQLENS 608
A R A+ + + + R+ E S
Sbjct: 1199 EAERAARARVEKQRAEAARELEELS 1223
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 52.8 bits (121), Expect = 3e-06
Identities = 104/457 (22%), Positives = 189/457 (41%), Gaps = 41/457 (8%)
Query: 29 KLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKRLRRDSS--GNGTTAP 86
KL TN FSDS Q I E L LT +++++I + RL + T
Sbjct: 460 KLETLTN-QFSDSKQHI-EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI 517
Query: 87 PSPWETKRLKI-DLIAAKAQITKLESRVNH-QHTIRKEMQILFEEEKA-SLIEQHKRDER 143
E K + ++ K + E +VN Q I + L ++EK S +++ + +
Sbjct: 518 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 577
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQ-IADLKDK--LLE 200
A + D K+ KE +D +E+ D +K+ + DLK+K LL+
Sbjct: 578 ADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQ 637
Query: 201 ANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQN- 258
++S K+ + ++K+ L A G + + + E+ + + E+C ++++QL+K +
Sbjct: 638 GDLSEKEASLLDLKEHASSL--ASSGLKKDSRLKTLEIALEQKK-EECLKMESQLKKAHE 694
Query: 259 --FEFQ---QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
E + +++ +++ LE E YKD +S AQ + + E+ KEV NE++ +
Sbjct: 695 AALEARASPEMSDRIQHLEREITRYKD---ESSKAQAEVDRLLEILKEVE----NEKNDK 747
Query: 314 DAICNKL--LLEEQVHQLTSRVEALQ-PVQLELHEAKVKLSSVESQLESWMSAARAHGVE 370
D +L L QV +V L+ Q+E ++ L + ++ +++ VE
Sbjct: 748 DKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQVE 807
Query: 371 SAGALRDALESAL-GXXXXXXXXXXXXXXXXXHLT----------EEVATLKYERDKATG 419
+ ++ L HLT EEV +K E A
Sbjct: 808 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAI 867
Query: 420 KLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
D S + Q+ + + RE+D QQL
Sbjct: 868 SEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQL 904
Score = 50.4 bits (115), Expect = 2e-05
Identities = 77/355 (21%), Positives = 148/355 (41%), Gaps = 36/355 (10%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRD----ERAV 145
K L+ D +T LE + + TI KE + E EK I+ +K+D + V
Sbjct: 574 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 633
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEH-------KDLKANWDKEKTDLHKQIADLK--- 195
S ++ K+ ++ A K L+ +++K + K + LK
Sbjct: 634 SLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 693
Query: 196 DKLLEANVSNK--DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
+ LEA S + D+I +++++ AQ+EV+ L E++K+ KN
Sbjct: 694 EAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL-EILKEVENE------KND 746
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR 313
+K+ E + +TS+ +++ + + + + + +K+ M E R E +L
Sbjct: 747 KDKKIAELESLTSR--QVKDQNKKVANLKHKEQVEKKKSAQMLE------EARRREDNLN 798
Query: 314 DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAG 373
D+ +L +EE + + + L+ ++ +L + L+ E+ L + + R H E
Sbjct: 799 DS-SQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLE 857
Query: 374 ALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
++AL +A+ EEVA LK E+D+ +L T R
Sbjct: 858 MKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKREKDRLVQQLKQQTQNR 911
Score = 42.3 bits (95), Expect = 0.005
Identities = 100/469 (21%), Positives = 197/469 (42%), Gaps = 34/469 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFE-----EEKASLIEQHKRDERA- 144
E R +L+A + TKLE+ N ++ +++L E E++A++++ R
Sbjct: 446 ELSRKDTELLALQ---TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 145 VSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD-KEK--TDLHKQIADLKDKLL-- 199
+ + E +E T A E DLK D KE+ L K+I +L+++L
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 200 EANVSN-KDQISEMKKDM---DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
E +S+ K+++ ++ D D L LE A +E E + L +Q R E+ + + +++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER--EKQEEID 620
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+ + + K+ L+ + + K L + + L+K+ +RL+ E +L
Sbjct: 621 NYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS-SGLKKD-SRLKTLEIALEQK 678
Query: 316 ICNKLLLEEQVHQLTSRVEALQP-VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGA 374
L +E Q+ + + AL+ E+ + L ++ + S A+A
Sbjct: 679 KEECLKMESQLKK--AHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEI 736
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY----ERDKATGKLNDLTTVRKN 430
L++ ++VA LK+ E+ K+ L + N
Sbjct: 737 LKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 796
Query: 431 QESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT--LCGEEGAGSVALLSARVQQLEK 488
+LQ LL+ E+ +Q+L+ + +L+ T E+ L + R + LE+
Sbjct: 797 LNDSSQQLQVEELLMAMEK--VKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 854
Query: 489 SLQGYRD-LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ 536
L+ ++ L+AA + AL L + + +EE +R+ +L Q
Sbjct: 855 VLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQ 903
Score = 41.5 bits (93), Expect = 0.009
Identities = 101/515 (19%), Positives = 214/515 (41%), Gaps = 48/515 (9%)
Query: 109 LESRVNHQHTIRKEMQILFE------EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
LE + +R+EM FE + KA +D + +S ME
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK-ISSMERGLRDLEEEIQML 408
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQ 221
K + +E ++ + ++ H + K ++ +S KD ++ ++ ++ L
Sbjct: 409 KSNGALSTEEREEEMKQMEVYRS--HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 466
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKD 280
++ +E+LK+ L T++ ++ L+ +++ ++ + L K+ + +D ++
Sbjct: 467 QFSDSKQHIEVLKESL---TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 523
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
TQ+ + E++V L+ +L++ + +K E+Q+ L RV++LQ
Sbjct: 524 KGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK---EKQMSSLKERVKSLQA-- 578
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ L+++E L A + +E RD E
Sbjct: 579 -DTTNTDTALTTLEEAL-----AEKERTIERLKEQRDRDERE------KQEEIDNYKKDL 626
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR-LQKRLLLVTRERDSYRQQLDCY 459
L E+V+ L+ + + L DL +++ SL L+K L T E +++ +C
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDL---KEHASSLASSGLKKDSRLKTLEIALEQKKEECL 683
Query: 460 EKELTVTLCGEEGAGSVAL--LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+ E + E + A +S R+Q LE+ + Y+D SKA + + +
Sbjct: 684 KMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD--------ESSKAQAEV-DRLL 734
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
+E E + D K + + LT S + KV +L + E +K+ ++ LE A+
Sbjct: 735 EILKEVENEKNDKDKKIAELESLT-SRQVKDQNKKVANLKHKEQVE-KKKSAQMLEEARR 792
Query: 578 EIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
L + ++ + +++++Q+LE+ + KL
Sbjct: 793 REDNLNDSSQQLQVEELLMAMEKVKQELESMKAKL 827
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 52.4 bits (120), Expect = 5e-06
Identities = 123/648 (18%), Positives = 271/648 (41%), Gaps = 54/648 (8%)
Query: 4 ESDMSLYSDVLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNL-LTFGKRKSSI 62
++ + L + V E R+ + E +L+A D +K+ + +L LT K +
Sbjct: 912 KNKIQLEAKVKEMNERLEDEEEMNAELTAKKR-KLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 63 GSVDDVTPDKRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKE 122
+ ++ K L + +G E K L+ A + E +VN + +
Sbjct: 971 HATENKV--KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVK 1028
Query: 123 MQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDK 182
++ ++ + SL EQ K+ D+E ++ + L+ K
Sbjct: 1029 LEQQVDDLEGSL-EQEKKVRM---DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKK 1084
Query: 183 EKTDLHKQIADLKDK-LLEANVSNKDQISEMK-KDMDELLQALEGAQSEVEMLKKELVKQ 240
++ D+++Q + ++D+ +L + K + ++ + ++++E L+A A+++VE L+ +L ++
Sbjct: 1085 KEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRE 1144
Query: 241 ----TSRAEQC---TQLKNQL-EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL 292
+ R E+ T ++ ++ +K+ EFQ++ L+E + ++ T + +K
Sbjct: 1145 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA-----TAAALRKKHA 1199
Query: 293 CNMAELEKEVTRL-RANERSLRDAICNKLLLE------EQVHQLTSRVEAL-QPVQLELH 344
++AEL +++ L R ++ ++ KL L+ EQ+ + + +E + + ++ + +
Sbjct: 1200 DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQAN 1259
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALR--DALESALGXXXXXXXXXXXXXXXXXH 402
E +VKL + L + + E+ R + E+ +
Sbjct: 1260 EYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKR 1319
Query: 403 LTEEVATLKYERDKATGKL-NDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEK 461
EE K A +D +R+ E + ++++ Q YE
Sbjct: 1320 QLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYET 1379
Query: 462 ELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAH--SKALESLRNEVTRW 519
+ EE + L+ R+Q E++++ ++ + H +E L +V R
Sbjct: 1380 DAIQRT--EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1437
Query: 520 REEA---EGARRDVTKL---------RTQRDLLTASLERIGPQTKVLHLTN--NPAAEAQ 565
A + +R+ K+ +Q +L ++ E T++ L N + E
Sbjct: 1438 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1497
Query: 566 KQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ +E + QEEI L L EGG EL+++R+QLE +++L+
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNV--HELEKVRKQLEVEKLELQ 1543
Score = 45.2 bits (102), Expect = 7e-04
Identities = 107/576 (18%), Positives = 230/576 (39%), Gaps = 69/576 (11%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDM 148
PW KI + A+ K T+++E + E + S + + +E+ VS +
Sbjct: 830 PWMKLYFKIKPLLKSAETEK------EMATMKEEFGRIKETLEKSEARRKELEEKMVSLL 883
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDL---KANWDKEKTDLHKQIADLKDKLLEANVSN 205
++ +D N A + L K + + ++++++ D ++ E
Sbjct: 884 QEKNDLQLQVQAE-QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK 942
Query: 206 K---DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ 262
+ D+ SE+KKD+D+L L + E + ++ T ++ +L K+ Q
Sbjct: 943 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ 1002
Query: 263 QVTSK-LKELEYERDSYKDWQTQSKTAQKRLCNM---AELEKEVTR------------LR 306
+ + L +L+ E D ++++ ++ E EK+V L+
Sbjct: 1003 EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 307 ANERSLRDAICNKLLLEEQ-------VHQLTSRVE-----ALQPVQLELHEAKVKLSSVE 354
+ S+ D +KL LEE+ ++Q S++E ALQ +Q +L E + ++ +E
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ-LQKKLKENQARIEELE 1121
Query: 355 SQLESWMSA-ARAHGVES-----AGALRDALESALGXXXXXXXXXXXXXXXXXHLTE--E 406
+LE+ +A A+ + S + + LE A G + E
Sbjct: 1122 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLE 1181
Query: 407 VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVT 466
ATL++E A + +V + E I LQ+ + +E+ ++ +LD +
Sbjct: 1182 EATLQHEATAAALRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Query: 467 LCGEEGAGSVAL--------LSARVQQLEKSLQGYRDLIAAHDPHAHSKA-----LESLR 513
+ + V+ ++++ ++SL + A A E+L
Sbjct: 1241 IKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALI 1300
Query: 514 NEVTR----WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQIS 569
+++TR + ++ E +R + + ++ L +L+ +L EA+ ++
Sbjct: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Query: 570 KELEAAQEEIKKLKVALREGGAQADPEELQQMRQQL 605
+ L A E+ + + Q EEL++ +++L
Sbjct: 1361 RVLSKANSEVAQWRTKYETDAIQR-TEELEEAKKKL 1395
Score = 41.9 bits (94), Expect = 0.006
Identities = 90/470 (19%), Positives = 193/470 (41%), Gaps = 36/470 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + V ++E
Sbjct: 1475 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGEGGKNVHELEK 1530
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
+++ + ++ +D A +++EV +KK++ + E Q + + + +
Sbjct: 1591 NHQRVVDSLQTSLD----AETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1646
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CN 318
+ S LK+ + + D K N+A +E+ L+A LR + +
Sbjct: 1647 SLQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERS 1700
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA----RAHGVESAGA 374
+ L E+++ + + RV+ L L K K+ S +QL+S + A R ++ A
Sbjct: 1701 RKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKA 1760
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A ++ + + L++ D+A L + E+
Sbjct: 1761 ITDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1819
Query: 434 LIHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG 492
+ L+ L R +S + + +T EE ++ L V +L+ ++
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
Query: 493 YRDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDL 539
Y+ + A++ +++E+ E A+ A V KLR + RD+
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
>BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 52.4 bits (120), Expect = 5e-06
Identities = 87/461 (18%), Positives = 194/461 (42%), Gaps = 50/461 (10%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 422 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 481
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 482 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 532
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 533 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 589
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
S A SA L + L + TE+ +L ERD+ T K
Sbjct: 590 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQ-----------TED--SLASERDRLTSKE 634
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRE----RDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L ++ L +QK L + + + Q Y K+ + L E+ +
Sbjct: 635 EELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEI- 693
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
S ++++ K L + + + E +V E+ + + KL+T
Sbjct: 694 --SNKMEEF-KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE--KLKTVE 748
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+LL L ++ + + L+ + K++ ++L+A Q +
Sbjct: 749 ELLETGLIQVATKEEELNAIRTENSSLTKEV-QDLKAKQND 788
Score = 51.2 bits (117), Expect = 1e-05
Identities = 100/535 (18%), Positives = 214/535 (40%), Gaps = 38/535 (7%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
A K+++ KL++ V+ Q + ++M+ +E+ L K E +
Sbjct: 709 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKL----KTVEELLETGLIQVATKEEE 764
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE 218
+ E ++ KE +DLKA ++ + +LK + E + K ++ ++ +
Sbjct: 765 LNAIRTENSSLTKEVQDLKAK-QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLK 823
Query: 219 LLQALEGAQSEVEMLKKELVKQTS-RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ + Q + +EL + EQ +K LE++ + L++L+ E +S
Sbjct: 824 VANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 883
Query: 278 YKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
K Q ++ K + ++ E+ L+ E L+ + +L+E+ L+S+ + L
Sbjct: 884 LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL---EAMLKERESDLSSKTQLL 940
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXXXXXX 394
Q VQ E K ++ ++ Q S+ H ++ +
Sbjct: 941 QDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVE 1000
Query: 395 XXXXXXXHLTEE----VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL------L 444
L E+ + L K+N + R+ Q + K +L +
Sbjct: 1001 HQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKV 1060
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ-------LEKSLQGYRDLI 497
SY + L +EK+ + G G+ V +L ++++ L+ + Y+ ++
Sbjct: 1061 SVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVL 1120
Query: 498 AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
A + K S+ E +W+ + + + + + ++++ LER+ + K +
Sbjct: 1121 AETEGILQ-KLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDI--- 1176
Query: 558 NNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
N E ++ + ELE A+ E +RE AQ + E L ++R + +N R K+
Sbjct: 1177 ENLRRE-REHLEMELEKAEMERSTYVTEVRELKAQLN-ETLTKLRTE-QNERQKV 1228
Score = 51.2 bits (117), Expect = 1e-05
Identities = 112/536 (20%), Positives = 214/536 (39%), Gaps = 34/536 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K + D ++ + + +L+ ++ + K ++ L E E + + K + +++
Sbjct: 781 DLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQ 840
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
+ +E + AN K DL ++ LK + E N + S
Sbjct: 841 ELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEAS 900
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+ +EL L+ ++E++ L+ L ++ S TQL ++ +N F+ +LK+
Sbjct: 901 SASQ-FEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQ 959
Query: 271 LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLT 330
Y++ S ++ L ++E EKE++ L SL+DA+ ++ + +
Sbjct: 960 QNYQQAS------SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1013
Query: 331 -SRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESAL--GXXX 387
+EAL + L + KV +S E Q + A V + ++ S L G
Sbjct: 1014 WEAMEALASTEKMLQD-KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWL 1072
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLL 443
+EEV L+++ +A L + +S++ LQK
Sbjct: 1073 HGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR 1132
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
V +E + ++ ++D E T+ S L R++ K ++ R H
Sbjct: 1133 SVEQEENKWKVKVD--ESHKTIKQMQSSFTSSEQELE-RLRSENKDIENLR-REREHLEM 1188
Query: 504 AHSKALESLRNEVTRWREEAEGARRDVTKLRTQR--------DLLTA--SLERIGPQTKV 553
KA VT RE +TKLRT++ DL A SLE I Q+K+
Sbjct: 1189 ELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELI--QSKI 1246
Query: 554 LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
+ + +S E E++++E + V+L + Q + LQ + QQL +
Sbjct: 1247 VKAAGDTTVIENSDVSPETESSEKE--TMSVSLNQTVTQLQ-QLLQAVNQQLTKEK 1299
Score = 36.7 bits (81), Expect = 0.24
Identities = 59/278 (21%), Positives = 127/278 (45%), Gaps = 26/278 (9%)
Query: 103 KAQITKLESRVNHQ----HTIRKEMQILF-EEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
KA++ KL++ N Q H + K Q ++ +++K L+E+ + E + + ME+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS-NKMEEFKILNDQ 706
Query: 158 XXXXXKD--EFNTAAKE--HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMK 213
+ + T E +KD+ +K + +++ +++ LLE + Q++ +
Sbjct: 707 NKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE-LLETGLI---QVATKE 762
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
++++ + EV+ LK + Q S A +LK + +++ + + V +L E E
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV-EELLEAEL 821
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
+ + K+ KT Q L +++++ L+ E + K +LEE+ L +
Sbjct: 822 LKVANKE-----KTVQ--LSITSKVQELQNLLKGKEEQMNTM---KAVLEEKEKDLANTG 871
Query: 334 EALQPVQLELHEAKVKLSSV-ESQLESWMSAARAHGVE 370
+ LQ +Q E K + V + L+ SA++ +E
Sbjct: 872 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 909
Score = 32.3 bits (70), Expect = 5.3
Identities = 75/357 (21%), Positives = 135/357 (37%), Gaps = 33/357 (9%)
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE--RSLRDAICNKL 320
++T+ + +L+ E+D + A K C E + R+N ++D I L
Sbjct: 326 ELTTLIHQLQ-EKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRI-GTL 383
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALE 380
E V Q V + Q+++ K V Q+E A AH + G LRDA+
Sbjct: 384 EKEHNVFQNKIHVSYQETQQMQM-----KFQQVREQME----AEIAHLKQENGILRDAVS 434
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ L ++ A L E + TGKL +KN E +L+
Sbjct: 435 NTTNQLESKQSAELNK------LRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 488
Query: 441 RLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA-- 498
+L +E + +++ Y ++ T E A L S V + E +Q +
Sbjct: 489 QL----QEAERRWEEVQSYIRKRT----AEHEAAQQDLQSKFVAK-ENEVQSLHSKLTDT 539
Query: 499 -AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
+ ++ + +E R +E E + V + Q + L A +++ Q
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA 598
Query: 558 NNPAAEAQKQIS-KELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ A E K I+ K+ + Q E R + + +++Q M L+ KL+
Sbjct: 599 SVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ 655
>BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 52.4 bits (120), Expect = 5e-06
Identities = 87/461 (18%), Positives = 194/461 (42%), Gaps = 50/461 (10%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 422 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 481
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 482 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 532
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 533 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 589
Query: 362 SAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKL 421
S A SA L + L + TE+ +L ERD+ T K
Sbjct: 590 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQ-----------TED--SLASERDRLTSKE 634
Query: 422 NDLTTVRKNQESLIHRLQKRLLLVTRE----RDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L ++ L +QK L + + + Q Y K+ + L E+ +
Sbjct: 635 EELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEI- 693
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
S ++++ K L + + + E +V E+ + + KL+T
Sbjct: 694 --SNKMEEF-KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE--KLKTVE 748
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEE 578
+LL L ++ + + L+ + K++ ++L+A Q +
Sbjct: 749 ELLETGLIQVATKEEELNAIRTENSSLTKEV-QDLKAKQND 788
Score = 51.2 bits (117), Expect = 1e-05
Identities = 100/535 (18%), Positives = 214/535 (40%), Gaps = 38/535 (7%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
A K+++ KL++ V+ Q + ++M+ +E+ L K E +
Sbjct: 709 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKL----KTVEELLETGLIQVATKEEE 764
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDE 218
+ E ++ KE +DLKA ++ + +LK + E + K ++ ++ +
Sbjct: 765 LNAIRTENSSLTKEVQDLKAK-QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLK 823
Query: 219 LLQALEGAQSEVEMLKKELVKQTS-RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ + Q + +EL + EQ +K LE++ + L++L+ E +S
Sbjct: 824 VANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 883
Query: 278 YKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
K Q ++ K + ++ E+ L+ E L+ + +L+E+ L+S+ + L
Sbjct: 884 LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL---EAMLKERESDLSSKTQLL 940
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALRDALESALGXXXXXXXXXX 394
Q VQ E K ++ ++ Q S+ H ++ +
Sbjct: 941 QDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVE 1000
Query: 395 XXXXXXXHLTEE----VATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL------L 444
L E+ + L K+N + R+ Q + K +L +
Sbjct: 1001 HQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKV 1060
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ-------LEKSLQGYRDLI 497
SY + L +EK+ + G G+ V +L ++++ L+ + Y+ ++
Sbjct: 1061 SVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVL 1120
Query: 498 AAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
A + K S+ E +W+ + + + + + ++++ LER+ + K +
Sbjct: 1121 AETEGILQ-KLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDI--- 1176
Query: 558 NNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
N E ++ + ELE A+ E +RE AQ + E L ++R + +N R K+
Sbjct: 1177 ENLRRE-REHLEMELEKAEMERSTYVTEVRELKAQLN-ETLTKLRTE-QNERQKV 1228
Score = 51.2 bits (117), Expect = 1e-05
Identities = 112/536 (20%), Positives = 214/536 (39%), Gaps = 34/536 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K + D ++ + + +L+ ++ + K ++ L E E + + K + +++
Sbjct: 781 DLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQ 840
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
+ +E + AN K DL ++ LK + E N + S
Sbjct: 841 ELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEAS 900
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
+ +EL L+ ++E++ L+ L ++ S TQL ++ +N F+ +LK+
Sbjct: 901 SASQ-FEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQ 959
Query: 271 LEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLT 330
Y++ S ++ L ++E EKE++ L SL+DA+ ++ + +
Sbjct: 960 QNYQQAS------SFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1013
Query: 331 -SRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESAL--GXXX 387
+EAL + L + KV +S E Q + A V + ++ S L G
Sbjct: 1014 WEAMEALASTEKMLQD-KVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWL 1072
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR----LQKRLL 443
+EEV L+++ +A L + +S++ LQK
Sbjct: 1073 HGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR 1132
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
V +E + ++ ++D E T+ S L R++ K ++ R H
Sbjct: 1133 SVEQEENKWKVKVD--ESHKTIKQMQSSFTSSEQELE-RLRSENKDIENLR-REREHLEM 1188
Query: 504 AHSKALESLRNEVTRWREEAEGARRDVTKLRTQR--------DLLTA--SLERIGPQTKV 553
KA VT RE +TKLRT++ DL A SLE I Q+K+
Sbjct: 1189 ELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELI--QSKI 1246
Query: 554 LHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSR 609
+ + +S E E++++E + V+L + Q + LQ + QQL +
Sbjct: 1247 VKAAGDTTVIENSDVSPETESSEKE--TMSVSLNQTVTQLQ-QLLQAVNQQLTKEK 1299
Score = 36.7 bits (81), Expect = 0.24
Identities = 59/278 (21%), Positives = 127/278 (45%), Gaps = 26/278 (9%)
Query: 103 KAQITKLESRVNHQ----HTIRKEMQILF-EEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
KA++ KL++ N Q H + K Q ++ +++K L+E+ + E + + ME+
Sbjct: 648 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEIS-NKMEEFKILNDQ 706
Query: 158 XXXXXKD--EFNTAAKE--HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMK 213
+ + T E +KD+ +K + +++ +++ LLE + Q++ +
Sbjct: 707 NKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE-LLETGLI---QVATKE 762
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
++++ + EV+ LK + Q S A +LK + +++ + + V +L E E
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV-EELLEAEL 821
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
+ + K+ KT Q L +++++ L+ E + K +LEE+ L +
Sbjct: 822 LKVANKE-----KTVQ--LSITSKVQELQNLLKGKEEQMNTM---KAVLEEKEKDLANTG 871
Query: 334 EALQPVQLELHEAKVKLSSV-ESQLESWMSAARAHGVE 370
+ LQ +Q E K + V + L+ SA++ +E
Sbjct: 872 KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 909
Score = 32.3 bits (70), Expect = 5.3
Identities = 75/357 (21%), Positives = 135/357 (37%), Gaps = 33/357 (9%)
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE--RSLRDAICNKL 320
++T+ + +L+ E+D + A K C E + R+N ++D I L
Sbjct: 326 ELTTLIHQLQ-EKDKLLAAVKEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRI-GTL 383
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALE 380
E V Q V + Q+++ K V Q+E A AH + G LRDA+
Sbjct: 384 EKEHNVFQNKIHVSYQETQQMQM-----KFQQVREQME----AEIAHLKQENGILRDAVS 434
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ L ++ A L E + TGKL +KN E +L+
Sbjct: 435 NTTNQLESKQSAELNK------LRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 488
Query: 441 RLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA-- 498
+L +E + +++ Y ++ T E A L S V + E +Q +
Sbjct: 489 QL----QEAERRWEEVQSYIRKRT----AEHEAAQQDLQSKFVAK-ENEVQSLHSKLTDT 539
Query: 499 -AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLT 557
+ ++ + +E R +E E + V + Q + L A +++ Q
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKE-ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSA 598
Query: 558 NNPAAEAQKQIS-KELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ A E K I+ K+ + Q E R + + +++Q M L+ KL+
Sbjct: 599 SVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ 655
>BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3
(Drosophila) protein.
Length = 718
Score = 52.4 bits (120), Expect = 5e-06
Identities = 49/257 (19%), Positives = 117/257 (45%), Gaps = 4/257 (1%)
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL +Q+ ++L EA +S K++I++ ++D + AL+ +S + + L+++ ++++
Sbjct: 173 DLDRQLKKTTEELNEA-LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD 231
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSKTAQKRLCNMAELEKEVTR 304
+ +++ + Q +L+E + ++ KD ++ + + +K + + + E+T
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM--S 362
L +SL+D I ++V +L +VE+ + +L + + ++ +E + +M +
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNT 351
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
+ + A A R LE+ L E LK + D + +
Sbjct: 352 VSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKD 411
Query: 423 DLTTVRKNQESLIHRLQ 439
L T R + + I L+
Sbjct: 412 RLRTERDSLKETIEELR 428
Score = 43.6 bits (98), Expect = 0.002
Identities = 62/292 (21%), Positives = 113/292 (38%), Gaps = 25/292 (8%)
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK-- 319
Q++ SK + D+Y D Q K + L N A KE R +E ++ A +
Sbjct: 155 QELMSKESPVSAGNDAYVDLDRQLKKTTEEL-NEALSAKEEIAQRCHELDMQVAALQEEK 213
Query: 320 --LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA-RAHGVESAGALR 376
LL E QV L R+ ++ A + +++QLE R + +R
Sbjct: 214 SSLLAENQV--LMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIR 271
Query: 377 -DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
+ LE + L +E+ L++ DK + + + +K E L
Sbjct: 272 CEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDL- 330
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
L++++ L+ + Y Q E+EL + +V +L+ L
Sbjct: 331 GDLRRQVKLLEEKNTMYMQNTVSLEEELRKA---NAARSQLETYKRQVVELQNRLS---- 383
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
SK + L E R +E+ + +++ +LRT+RD L ++E +
Sbjct: 384 --------EESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEEL 427
Score = 41.9 bits (94), Expect = 0.006
Identities = 78/390 (20%), Positives = 154/390 (39%), Gaps = 27/390 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
KE +L+ D E T L + LKD++ + + D++S+++ ++ + LE
Sbjct: 277 KEISELRQQND-ELTTLADEAQSLKDEI-DVLRHSSDKVSKLEGQVESYKKKLEDLGDLR 334
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV-TSKLKELEYERDSYKDWQTQSKT-- 287
+K K T + L+ +L K N Q+ T K + +E + ++ + K
Sbjct: 335 RQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDF 394
Query: 288 AQKRLCNMAE-LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR-------VEALQPV 339
KRL + L+KE RLR SL++ I ++ Q QLT++ E+ +
Sbjct: 395 EYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSL 454
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGV--ESAGALRDALESALGXXXXXXXXXXXXX 397
E+ +++ + Q E+ M G E L+ L+ A
Sbjct: 455 AAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVN 514
Query: 398 XXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ +V L+ K D ++K E + +L + E R ++
Sbjct: 515 QRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHE----ANNELQKKRAIIE 570
Query: 458 CYEKEL-TVTLCGEEGAGSVALLSARVQQLE----KSLQGYRDLIAAHDPHAHSKA---L 509
E +L EE ++ ++Q+E K L+ + +I DP + A +
Sbjct: 571 DLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEI 630
Query: 510 ESLRNEVTRWREEAEGARRDVTKLRTQRDL 539
++L+N++ ++ K ++QR++
Sbjct: 631 QALKNQLQERDRLFHSLEKEYEKTKSQREM 660
>BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein.
Length = 597
Score = 52.4 bits (120), Expect = 5e-06
Identities = 49/257 (19%), Positives = 117/257 (45%), Gaps = 4/257 (1%)
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL +Q+ ++L EA +S K++I++ ++D + AL+ +S + + L+++ ++++
Sbjct: 173 DLDRQLKKTTEELNEA-LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD 231
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSKTAQKRLCNMAELEKEVTR 304
+ +++ + Q +L+E + ++ KD ++ + + +K + + + E+T
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM--S 362
L +SL+D I ++V +L +VE+ + +L + + ++ +E + +M +
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNT 351
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
+ + A A R LE+ L E LK + D + +
Sbjct: 352 VSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKD 411
Query: 423 DLTTVRKNQESLIHRLQ 439
L T R + + I L+
Sbjct: 412 RLRTERDSLKETIEELR 428
Score = 43.6 bits (98), Expect = 0.002
Identities = 62/292 (21%), Positives = 113/292 (38%), Gaps = 25/292 (8%)
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK-- 319
Q++ SK + D+Y D Q K + L N A KE R +E ++ A +
Sbjct: 155 QELMSKESPVSAGNDAYVDLDRQLKKTTEEL-NEALSAKEEIAQRCHELDMQVAALQEEK 213
Query: 320 --LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA-RAHGVESAGALR 376
LL E QV L R+ ++ A + +++QLE R + +R
Sbjct: 214 SSLLAENQV--LMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIR 271
Query: 377 -DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
+ LE + L +E+ L++ DK + + + +K E L
Sbjct: 272 CEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDL- 330
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
L++++ L+ + Y Q E+EL + +V +L+ L
Sbjct: 331 GDLRRQVKLLEEKNTMYMQNTVSLEEELRKA---NAARSQLETYKRQVVELQNRLS---- 383
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
SK + L E R +E+ + +++ +LRT+RD L ++E +
Sbjct: 384 --------EESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEEL 427
Score = 40.3 bits (90), Expect = 0.020
Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 6/166 (3%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
KE +L+ D E T L + LKD++ + + D++S+++ ++ + LE
Sbjct: 277 KEISELRQQND-ELTTLADEAQSLKDEI-DVLRHSSDKVSKLEGQVESYKKKLEDLGDLR 334
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV-TSKLKELEYERDSYKDWQTQSKT-- 287
+K K T + L+ +L K N Q+ T K + +E + ++ + K
Sbjct: 335 RQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDF 394
Query: 288 AQKRLCNMAE-LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
KRL + L+KE RLR SL++ I ++ Q QLT++
Sbjct: 395 EYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQ 440
Score = 39.9 bits (89), Expect = 0.026
Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 7/99 (7%)
Query: 172 EHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
E+K LK N +E +D +++IA L+ L +AN+ + +E + LL+ QS+VE
Sbjct: 473 ENKMLKLN--QEGSD-NEKIALLQSLLDDANLRKNELETENRLVNQRLLEV----QSQVE 525
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
L+K L Q S+AE LK +LE+ + + ++L++
Sbjct: 526 ELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQK 564
>AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated
microtubule-binding protein HOOK3 protein.
Length = 718
Score = 52.4 bits (120), Expect = 5e-06
Identities = 49/257 (19%), Positives = 117/257 (45%), Gaps = 4/257 (1%)
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL +Q+ ++L EA +S K++I++ ++D + AL+ +S + + L+++ ++++
Sbjct: 173 DLDRQLKKTTEELNEA-LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD 231
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSKTAQKRLCNMAELEKEVTR 304
+ +++ + Q +L+E + ++ KD ++ + + +K + + + E+T
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM--S 362
L +SL+D I ++V +L +VE+ + +L + + ++ +E + +M +
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNT 351
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
+ + A A R LE+ L E LK + D + +
Sbjct: 352 VSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKD 411
Query: 423 DLTTVRKNQESLIHRLQ 439
L T R + + I L+
Sbjct: 412 RLRTERDSLKETIEELR 428
Score = 43.6 bits (98), Expect = 0.002
Identities = 62/292 (21%), Positives = 113/292 (38%), Gaps = 25/292 (8%)
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK-- 319
Q++ SK + D+Y D Q K + L N A KE R +E ++ A +
Sbjct: 155 QELMSKESPVSAGNDAYVDLDRQLKKTTEEL-NEALSAKEEIAQRCHELDMQVAALQEEK 213
Query: 320 --LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA-RAHGVESAGALR 376
LL E QV L R+ ++ A + +++QLE R + +R
Sbjct: 214 SSLLAENQV--LMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIR 271
Query: 377 -DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
+ LE + L +E+ L++ DK + + + +K E L
Sbjct: 272 CEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDL- 330
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
L++++ L+ + Y Q E+EL + +V +L+ L
Sbjct: 331 GDLRRQVKLLEEKNTMYMQNTVSLEEELRKA---NAARSQLETYKRQVVELQNRLS---- 383
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERI 547
SK + L E R +E+ + +++ +LRT+RD L ++E +
Sbjct: 384 --------EESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEEL 427
Score = 41.9 bits (94), Expect = 0.006
Identities = 78/390 (20%), Positives = 154/390 (39%), Gaps = 27/390 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
KE +L+ D E T L + LKD++ + + D++S+++ ++ + LE
Sbjct: 277 KEISELRQQND-ELTTLADEAQSLKDEI-DVLRHSSDKVSKLEGQVESYKKKLEDLGDLR 334
Query: 231 EMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV-TSKLKELEYERDSYKDWQTQSKT-- 287
+K K T + L+ +L K N Q+ T K + +E + ++ + K
Sbjct: 335 RQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDF 394
Query: 288 AQKRLCNMAE-LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR-------VEALQPV 339
KRL + L+KE RLR SL++ I ++ Q QLT++ E+ +
Sbjct: 395 EYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSL 454
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGV--ESAGALRDALESALGXXXXXXXXXXXXX 397
E+ +++ + Q E+ M G E L+ L+ A
Sbjct: 455 AAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVN 514
Query: 398 XXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
+ +V L+ K D ++K E + +L + E R ++
Sbjct: 515 QRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHE----ANNELQKKRAIIE 570
Query: 458 CYEKEL-TVTLCGEEGAGSVALLSARVQQLE----KSLQGYRDLIAAHDPHAHSKA---L 509
E +L EE ++ ++Q+E K L+ + +I DP + A +
Sbjct: 571 DLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEI 630
Query: 510 ESLRNEVTRWREEAEGARRDVTKLRTQRDL 539
++L+N++ ++ K ++QR++
Sbjct: 631 QALKNQLQERDRLFHSLEKEYEKTKSQREM 660
>Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.
Length = 1356
Score = 52.0 bits (119), Expect = 6e-06
Identities = 96/513 (18%), Positives = 220/513 (42%), Gaps = 45/513 (8%)
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIAD 193
++ + +R ++ M+D +++ + + +E + ++ + + + + +IA
Sbjct: 361 MMTEKERSNVVMTRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 420
Query: 194 LKDK--LLEANVSN------KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
LK + +L VSN Q +E+ K + + + + L++E V++ + +
Sbjct: 421 LKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ 480
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRL 305
TQLK QL++ +++V S +++ E ++ + QSK K E EV L
Sbjct: 481 AATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQ-DLQSKFVAK--------ENEVQSL 531
Query: 306 RANERSLRDAICNKLLLEEQVHQL----TSRVEALQPVQLELHEAKVKLSSVESQLESWM 361
+ L D + +K LE+++ QL RV + +Q+++ + + ++++Q++ +
Sbjct: 532 HS---KLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH 588
Query: 362 SAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLT---EEVATLKYERDKA 417
S A SA L + L + LT EE+ ++
Sbjct: 589 SQIAAQ--TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLL 646
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGA---G 474
++ L + Q + H L+K V + D R + + E++ + EE
Sbjct: 647 KAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKM--EEFKILND 704
Query: 475 SVALLSARVQQLEK--SLQGYRDLIAAHDPHAHSK--ALESLRNEVTRWREEAEGARRDV 530
L + VQ+L+ S Q +D++ + K L+++ + + ++
Sbjct: 705 QNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEEL 764
Query: 531 TKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK---ELEAAQE--EIKKLKVA 585
+RT+ LT ++ + + + E +K I + ++++ +E E + LKVA
Sbjct: 765 NAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVA 824
Query: 586 LREGGAQADPEELQQMRQQLENSRI-KLKRYSI 617
+E Q +E++ +++++ N ++ K ++ SI
Sbjct: 825 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSI 857
Score = 50.4 bits (115), Expect = 2e-05
Identities = 101/555 (18%), Positives = 226/555 (40%), Gaps = 48/555 (8%)
Query: 101 AAKAQITKLESRVNHQHT--IRKEMQILFEE--EKASLIEQHKRDE--RAVSDMEDXXXX 154
A K+++ KL++ V+ Q + ++M+ +E EK +E+ + + E+
Sbjct: 708 ALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 767
Query: 155 XXXXXXXXKDEFNTAAKEHKDLK-ANWDKE-KTDLHKQIADLK--DKLLEANVSNKDQIS 210
K+ + AK++ + A+ +E K +H++ +K ++LLEA +
Sbjct: 768 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 827
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-----------EQCTQLKNQLEKQNF 259
+ +D+ + ++AL+ V++ K + + TS+ EQ +K LE++
Sbjct: 828 KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEK 887
Query: 260 EFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ L++L+ E +S K Q ++ K + ++ E+ L+ L+
Sbjct: 888 DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKGNELKRL--- 944
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG--VESAGALR 376
+ +L+E+ L+S+ + LQ VQ E K ++ ++ Q S+ H ++
Sbjct: 945 EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISERE 1004
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEE----VATLKYERDKATGKLNDLTTVRKNQE 432
+ L E+ + L K+N + R+ Q
Sbjct: 1005 KEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQV 1064
Query: 433 SLIHRLQKRLL------LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ- 485
+ K +L + SY + L +EK+ + G G+ V +L ++++
Sbjct: 1065 EAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEA 1124
Query: 486 ------LEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDL 539
L+ + Y+ ++A + K S+ E +W+ + + + + + ++++
Sbjct: 1125 DEMHTLLQLECEKYKSVLAETE-GILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTS 1183
Query: 540 LTASLERIGPQTKVLHLTNNPAAEAQKQISK-ELEAAQ--EEIKKLKVALREGGAQADPE 596
LER+ + K + + ++ K E+E + E+++LK L E + D
Sbjct: 1184 SEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS 1243
Query: 597 ELQQMRQQLENSRIK 611
+ +RQ E + +K
Sbjct: 1244 YSEAVRQNEELNLLK 1258
Score = 31.5 bits (68), Expect = 9.2
Identities = 28/190 (14%), Positives = 75/190 (39%), Gaps = 3/190 (1%)
Query: 180 WDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
W + + HK I ++ + +++ KD++ L + E + E+E + E
Sbjct: 1163 WKVKVDESHKTIKQMQSSFTSSE-QELERLRSENKDIENLRREREHLEMELEKAEMERST 1221
Query: 240 QTSRAEQCTQLKNQLEKQ-NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-E 297
+ + L +L+K+ + + + + +EL + + T+ +T Q +A +
Sbjct: 1222 YVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGD 1281
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
L K L + + A + ++E + + + + L++ +L + +
Sbjct: 1282 LHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAV 1341
Query: 358 ESWMSAARAH 367
++ + H
Sbjct: 1342 NQQLTKEKEH 1351
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 52.0 bits (119), Expect = 6e-06
Identities = 114/531 (21%), Positives = 213/531 (40%), Gaps = 53/531 (9%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTA 169
E+ + + K+++ L E+EKA+ +E ++ + ++ D K E +
Sbjct: 593 EASLRERDAALKQLEAL-EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRK 651
Query: 170 AKEHKDLKANWDKEKTDLHKQIADLKDKLL--EANVSNKDQISEMKKDMDELLQAL-EGA 226
+E + +E+ + Q+A+L+ +L + + K+++++ K + E LQAL E
Sbjct: 652 VEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESL 711
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDW---- 281
+ L++E + E+ + ++L+ + +Q + KELE ER K
Sbjct: 712 KVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARL 771
Query: 282 -------QTQSKTAQKRLCN-MAE---LEKEVTRLRANERSLRDAICNKLLLEEQV---- 326
Q +++ ++ L MA E E +L + RD + E Q
Sbjct: 772 LQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMF 831
Query: 327 -HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGX 385
QL + E + + EL EAK K++ +ES E +S + E L AL+
Sbjct: 832 QEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNKLAELHANLARALQQV--- 888
Query: 386 XXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGK--LNDLTTVRKNQESLIHRLQKRLL 443
L ++++TL+ E+ AT K T VRK E R L
Sbjct: 889 --------QEKEVRAQKLADDLSTLQ-EKMAATSKEVARLETLVRKAGEQ--QETASREL 937
Query: 444 LVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPH 503
+ R RQ + E++ C + A + + +Q+ L+ R +
Sbjct: 938 VKEPARAGDRQP-EWLEEQQGRQFCSTQAA--LQAMEREAEQMGNELERLRAALMESQGQ 994
Query: 504 AHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAE 563
+ + R EV R +E A+ D+ + R L L+ + +V T E
Sbjct: 995 QQEERGQQER-EVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFAT---LQE 1050
Query: 564 AQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
A E E +E+ KL+ G A +EL+++RQ ++ + +L +
Sbjct: 1051 ALAHALTEKEGKDQELAKLR-----GLEAAQIKELEELRQTVKQLKEQLAK 1096
Score = 50.4 bits (115), Expect = 2e-05
Identities = 102/499 (20%), Positives = 198/499 (39%), Gaps = 55/499 (11%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
K ES H K+ Q L + EK+ + + + D+ +D N
Sbjct: 284 KNESLTMRLHETLKQCQDL-KTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALN 342
Query: 168 TAAKEHKDLKANWDKEKTDLHKQI-ADLKDK--LLEANVSNKDQISEMKKDMDELLQALE 224
+EH W +++ L K++ A L+DK L E N + ++S++++ + +L
Sbjct: 343 ELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQD--N 400
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
Q + E+L L +T + E T N + Q ++++ LE ER Q +
Sbjct: 401 PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQ--------ARVEMLETERG-----QQE 447
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+K +R E+E +L + L+ +I N +E++ Q + A Q+
Sbjct: 448 AKLLAER----GHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQV--- 500
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
+S+ S+L + + + E AG + A E +
Sbjct: 501 ------ASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE 554
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
+ ++LK + + R++ + + RERD+ +QL+ EK
Sbjct: 555 QLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK--- 611
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALESLRNEVTRWREE 522
E A + +L ++Q ++ + + A + S+ +E L+ V R+E
Sbjct: 612 ------EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A+ V +L Q L + ++ + +V A+ + Q+ ++L+A +E +K
Sbjct: 666 QHEAQAQVAELELQ---LRSEQQKATEKERV--------AQEKDQLQEQLQALKESLKVT 714
Query: 583 KVALREGGAQ-ADPEELQQ 600
K +L E + AD E QQ
Sbjct: 715 KGSLEEEKRRAADALEEQQ 733
Score = 43.2 bits (97), Expect = 0.003
Identities = 40/184 (21%), Positives = 82/184 (44%), Gaps = 3/184 (1%)
Query: 177 KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKE 236
+ + +E+ L Q+ +L KL +++ ++K Q ++K + ++ + AQ L E
Sbjct: 1523 RQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRFQAQL-NE 1581
Query: 237 LVKQTSRAEQCTQ-LKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM 295
L Q S+ EQ + K Q+EK + + +EL+ + S + Q ++K + +
Sbjct: 1582 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERL 1641
Query: 296 A-ELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE 354
EL++ + + E++ R LE QV ++ L Q+ K + +
Sbjct: 1642 GHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1701
Query: 355 SQLE 358
QL+
Sbjct: 1702 PQLD 1705
Score = 42.3 bits (95), Expect = 0.005
Identities = 97/483 (20%), Positives = 187/483 (38%), Gaps = 30/483 (6%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
F +A+L + E+ +++E ++E +E L + + D
Sbjct: 960 FCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQAD 1019
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L + A + LE + N ++E + + L +AL A +E E +EL K R +
Sbjct: 1020 LALEKAARAE--LEMRLQNA--LNEQRVEFATLQEALAHALTEKEGKDQELAKL--RGLE 1073
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRL 305
Q+K +LE+ +Q+ +L + E E S Q+++ + E L EV++L
Sbjct: 1074 AAQIK-ELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKL 1132
Query: 306 RAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS-- 362
++ A + LE + R AL+ +Q +L E +L +S L S
Sbjct: 1133 EQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQREL 1192
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
AA V+ D ++ + L EEV+ L + + G+
Sbjct: 1193 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISS---LEEEVSILNRQVLEKEGESK 1249
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
+L + + +L++ + RQ E + LCG A
Sbjct: 1250 ELKRLVMAESEKSQKLEESCACCRQ-----RQPATVPELQNAALLCGRR-------CRAS 1297
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTA 542
++ EK +L + + ++ E L E+ W+E+ + ++ L+ + A
Sbjct: 1298 GREAEKQRVASENL--RQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQA 1355
Query: 543 SLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMR 602
+ + P + A A+K+ +ELE +++ L+ L AQ + EL +R
Sbjct: 1356 LVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLR--AQRELGELIPLR 1413
Query: 603 QQL 605
Q++
Sbjct: 1414 QKV 1416
Score = 41.1 bits (92), Expect = 0.011
Identities = 53/262 (20%), Positives = 109/262 (41%), Gaps = 28/262 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ L++ L + + + T+ E + +++++Q L E K + + RA +E+
Sbjct: 672 QVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEE 731
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
K E + ++HK + ++E+ L+ +LL+ +++ +
Sbjct: 732 QQRCISEL----KAETRSLVEQHKRERKELEEERAGRK----GLEARLLQLGEAHQAETE 783
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELV--------KQTSRA-------EQCTQLKNQLE 255
+++++ E + A A+SE E L KE+ Q A EQ LK + E
Sbjct: 784 VLRRELAEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECE 843
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
K E Q+ K+ +E + Q Q+K A+ N+A ++V + L D
Sbjct: 844 KARQELQEAKEKVAGIESHSELQISRQ-QNKLAELH-ANLARALQQVQEKEVRAQKLADD 901
Query: 316 ICNKLLLEEQVHQLTSRVEALQ 337
+ L+E++ + V L+
Sbjct: 902 LST---LQEKMAATSKEVARLE 920
Score = 37.1 bits (82), Expect = 0.18
Identities = 107/568 (18%), Positives = 220/568 (38%), Gaps = 55/568 (9%)
Query: 72 KRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
K+ + +SG+G + + T+ L A +A+++KLE + Q ++ E E+
Sbjct: 1096 KKEKEHASGSGAQSEAAG-RTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAER 1154
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKT 185
AS E+ E +E+ F T ++H + W K +
Sbjct: 1155 ASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEW-KAQV 1213
Query: 186 DLHKQIADLKDKLL-----EANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV-- 238
+Q A+ K+ L+ E ++ N+ Q+ E + + EL + + + + L++
Sbjct: 1214 ARGRQEAERKNSLISSLEEEVSILNR-QVLEKEGESKELKRLVMAESEKSQKLEESCACC 1272
Query: 239 KQTSRA-------------EQCTQLKNQLEKQNFEF----QQVTSKLKELEYERDSYKDW 281
+Q A +C + EKQ Q++TS+ + E K W
Sbjct: 1273 RQRQPATVPELQNAALLCGRRCRASGREAEKQRVASENLRQELTSQAERAEELGQELKAW 1332
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQL 341
Q + ++ L + +LE T+ +E +C +L E+ + R E L+ +
Sbjct: 1333 QEKFFQKEQALSTL-QLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHR-EELEQSKQ 1390
Query: 342 ELHEAKVKLSSVESQLESWMSAAR--AHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ +L + +L + + A +A LR S
Sbjct: 1391 AAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEE 1450
Query: 400 XXHLTEEV----ATLKYERDKATGK-LNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQ 454
L E L+ E D+A K + +L VR + E+ + +Q+ RE +
Sbjct: 1451 NRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTA 1510
Query: 455 QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
+ + ++ V + L+A+V++L K L + + L++++
Sbjct: 1511 KYE--GAKVKVLEERQRFQEERQKLTAQVEELSKKLAD-----SDQASKVQQQKLKAVQA 1563
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+ ++EA+ + + +L+ Q + E+ K+ +A+KQ ++EL+
Sbjct: 1564 QGGESQQEAQRFQAQLNELQAQ----LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE 1619
Query: 575 AQEEIKKLKVALREGGAQAD--PEELQQ 600
+++L+ +E A+A+ ELQQ
Sbjct: 1620 QLRSLEQLQKENKELRAEAERLGHELQQ 1647
Score = 35.9 bits (79), Expect = 0.43
Identities = 86/467 (18%), Positives = 176/467 (37%), Gaps = 25/467 (5%)
Query: 164 DEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKL---LEANVSNKDQISEMKKDMDELL 220
D + + + +A D L Q+ + +L A S + +++ + + +
Sbjct: 1144 DSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHS 1203
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
+A + +++V ++E ++ S + + L +Q E + + +LK L +S K
Sbjct: 1204 KAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMA-ESEKS 1262
Query: 281 WQTQSKTA---QKRLCNMAELEKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
+ + A Q++ + EL+ R S R+A ++ E +LTS+ E
Sbjct: 1263 QKLEESCACCRQRQPATVPELQNAALLCGRRCRASGREAEKQRVASENLRQELTSQAERA 1322
Query: 337 QPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+ + EL + K E L S + L A
Sbjct: 1323 EELGQELKAWQEKFFQKEQAL-STLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRH 1381
Query: 397 XXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQL 456
+ L+ E +A +L +L +R+ + ++ + E+ SY +QL
Sbjct: 1382 REELEQSKQAAGGLRAELLRAQRELGELIPLRQK----VAEQERTAQQLRAEKASYAEQL 1437
Query: 457 DCYEKELTVTLCGEEGAGSVALLSARVQQLE--KSLQGYRDLIAAHDPHAHSKALESLRN 514
+K + G G A L + ++E ++ + Y +AA A ++ E R
Sbjct: 1438 SMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQRE 1497
Query: 515 EVTRWRE------EAEGARRDVTKLRT----QRDLLTASLERIGPQTKVLHLTNNPAAEA 564
+ RE + EGA+ V + R +R LTA +E + + + +
Sbjct: 1498 AQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQK 1557
Query: 565 QKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIK 611
K + + +Q+E ++ + L E AQ +E +L+ + K
Sbjct: 1558 LKAVQAQGGESQQEAQRFQAQLNELQAQLSQKEQAAEHYKLQMEKAK 1604
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 52.0 bits (119), Expect = 6e-06
Identities = 95/463 (20%), Positives = 191/463 (41%), Gaps = 59/463 (12%)
Query: 173 HKDLKANWD---KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDEL---LQALEGA 226
+K L+A+ + K D+ K + +L+ ++ + + Q+ EM+ ++EL LQA E A
Sbjct: 1 NKQLRADMEDLMSSKDDVGKNVHELE----KSKRALEQQVEEMRTQLEELEDELQATEDA 56
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +E+ + + Q R Q +N+ EK+ +QV ELE ER K
Sbjct: 57 KLRLEVNMQAMKAQFERDLQTRDEQNE-EKKRLLIKQVRELEAELEDER---KQRALAVA 112
Query: 287 TAQKRLCNMAELEKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+ +K ++ +LE ++ +A + ++ + +++ +L + + + E
Sbjct: 113 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE 172
Query: 346 AKVKLSSVES---QLESWMSA---ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
++ KL S+E+ QL+ +++ AR H + L D + ++
Sbjct: 173 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 232
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCY 459
L EE+ E LND Q ++ ++ D+ RQQL+
Sbjct: 233 IAQLEEELE----EEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 288
Query: 460 EKELTVTLCGEEGA------GSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLR 513
KEL L EGA +++ L A++ QLE+ L+ A + A +K +
Sbjct: 289 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ-----EAKERAAANKLVRRTE 343
Query: 514 NEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
++ + E RR + + Q + A + KQ+ ++LE
Sbjct: 344 KKLKEIFMQVEDERRHADQYKEQMEKANARM---------------------KQLKRQLE 382
Query: 574 AAQEEIKKLKVALREGGAQAD--PEELQQMRQQLENSRIKLKR 614
A+EE + + R+ + D E + + +++ + +L+R
Sbjct: 383 EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 425
Score = 47.6 bits (108), Expect = 1e-04
Identities = 51/225 (22%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQALEGAQSE 229
K+ ++L+A + E+ + +A K +E ++ + + QI K DE+++ L Q++
Sbjct: 91 KQVRELEAELEDERKQ--RALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 148
Query: 230 VEMLKKELVK-QTSRAE---QCTQLKNQLEKQNFEFQQVTSKL-------KELEYERDSY 278
++ ++EL + + SR E Q + + +L+ E Q+ +L + E ERD
Sbjct: 149 MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 208
Query: 279 KDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP 338
D T S + + L + E + R+ E L + N LL ++ + T +V+ L
Sbjct: 209 ADEITNSASGKSALLD--EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNA 266
Query: 339 VQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESAL 383
A K + QLE +A E GA++ ++ +
Sbjct: 267 ELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATI 311
Score = 46.4 bits (105), Expect = 3e-04
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 24/279 (8%)
Query: 93 KRLKIDLIAAKAQI---TKLESRVNHQ----HTIRKEMQILFEEEKAS---LIEQHKRDE 142
K+++IDL +AQI K V Q K+ Q EE +AS + Q K E
Sbjct: 115 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 174
Query: 143 RAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN 202
+ + +E + A++ +D A+ + D K +L EA
Sbjct: 175 KKLKSLE-AEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EAR 232
Query: 203 VSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
++ ++++ E + +M+ L +V+ L EL + S A++ + QLE+QN
Sbjct: 233 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN--- 289
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL- 320
+++ +KL+ELE S K T S K + +LE+++ + A ER+ + + +
Sbjct: 290 KELKAKLQELEGAVKS-KFKATISALEAK----IGQLEEQLEQ-EAKERAAANKLVRRTE 343
Query: 321 -LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
L+E Q+ + ++ +A ++ ++ QLE
Sbjct: 344 KKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE 382
Score = 44.0 bits (99), Expect = 0.002
Identities = 84/426 (19%), Positives = 173/426 (40%), Gaps = 32/426 (7%)
Query: 117 HTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN----TAAKE 172
H + K + L E++ + Q + E + ED K +F T ++
Sbjct: 23 HELEKSKRAL-EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 81
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV-E 231
+++ K K+ +L ++ D + + A S K ++K D++ ++A A+ EV +
Sbjct: 82 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK-DLEAQIEAANKARDEVIK 140
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKR 291
L+K + + + + ++ + ++ KLK LE E ++ S+ A++
Sbjct: 141 QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRH 200
Query: 292 L-CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKL 350
EL E+T + + +L D K LE ++ QL +E Q L++ K
Sbjct: 201 AEQERDELADEITNSASGKSALLD---EKRRLEARIAQLEEELEEEQSNMELLNDRFRKT 257
Query: 351 SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATL 410
+ L + ++A R+ +S A R LE T ++ L
Sbjct: 258 TLQVDTLNAELAAERSAAQKSDNA-RQQLERQNKELKAKLQELEGAVKSKFKAT--ISAL 314
Query: 411 KYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGE 470
+ + + +L R L+ R +K+L + + + R+ D Y++++
Sbjct: 315 EAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM------- 367
Query: 471 EGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV 530
E A +AR++QL++ L+ A + + + L+ E+ E EG R+V
Sbjct: 368 EKA------NARMKQLKRQLEE-----AEEEATRANASRRKLQRELDDATEANEGLSREV 416
Query: 531 TKLRTQ 536
+ L+ +
Sbjct: 417 STLKNR 422
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 52.0 bits (119), Expect = 6e-06
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 262 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 321
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 322 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 372
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 373 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 430
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 431 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI-- 488
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 489 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 534
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 535 -----EELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 589
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL---EKSLQGYRDLIAAHDP 502
E +Y+ +L+ EKE L + L R Q L E+ L ++ +
Sbjct: 590 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIE-- 647
Query: 503 HAHSKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHL 556
H +E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L
Sbjct: 648 --HRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 705
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
+ ++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 706 QQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 31.9 bits (69), Expect = 6.9
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA-VSDMEDXXXXXXXXXXXX-KDEFN 167
ES+ +R ++ EEE + L E + + R + ++D ++E +
Sbjct: 616 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMS 675
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
+ + K N ++ L +I+ LKD L ++ V++K + EM ++EL Q
Sbjct: 676 QKIETMQFEKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------Q 725
Query: 228 SEVEMLK-KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQT 283
E+E+L+ +E K T E Q QLK + LEKQ E + + K +LE E KD +
Sbjct: 726 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EK 784
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
++ ++ E+ + L + + +D++ K +L+EE
Sbjct: 785 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 828
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 52.0 bits (119), Expect = 6e-06
Identities = 97/518 (18%), Positives = 214/518 (41%), Gaps = 39/518 (7%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
F + K SL++ E ++E + + + KDL+ + K++
Sbjct: 145 FTDAKRSLLQT----ESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 200
Query: 187 LHK--QIADLKDKLLEANVSNKDQISE-MKKDMDELLQALEGAQSEVEMLKK-ELVKQTS 242
L + +I KD + K++++E ++K ++ A +++LK+ E++ Q
Sbjct: 201 LKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAK 260
Query: 243 RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE--K 300
RAE +LK+Q+ Q E + +L + E + Q+K + + E E +
Sbjct: 261 RAE-LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTE 319
Query: 301 EVTRLRANERSLRDAICNK----LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ +R + L + K + + E+ QLT + ++ + L ++S +++
Sbjct: 320 KCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTE 379
Query: 357 LESWMSAARA--HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYER 414
L++ + + H ++ D S L ++++ + E
Sbjct: 380 LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKG-EIEW 438
Query: 415 DKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT----VTLCGE 470
K + + R ES LQ + +++E++ +++ D +EK+L V E
Sbjct: 439 QKQLLERDKREIERMTAES--RALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAE 496
Query: 471 EGA----GSVALLSARVQQLEKSL-QGYRDLIAAHDP--------HAHSKALESLRNEVT 517
E + ++ L V++L++ L Q RD ++ H+ +A+ SL+ E+
Sbjct: 497 ENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELA 556
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE 577
++ A++D+ +D+L + R+ + ++ ++L+ Q
Sbjct: 557 NVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQN 616
Query: 578 EIK--KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
EI+ KLK+ +E Q +E + +LE S++ LK
Sbjct: 617 EIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLK 654
Score = 48.0 bits (109), Expect = 1e-04
Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 23/197 (11%)
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
H D+ A ++ + + + L+++L ANV +D ++ K+D+ + + SE
Sbjct: 531 HNDISA-MQQQLQEKREAVNSLQEEL--ANV--QDHLNLAKQDLLHTTKHQDVLLSEQTR 585
Query: 233 LKKELVKQTSRAEQCTQ-----------LKNQLEKQNFEFQQVTSKLKELEYERDSYKDW 281
L+K++ + +R E C + L+N++E+ + Q + L+ ER+S +
Sbjct: 586 LQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESK 645
Query: 282 QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL-EEQVHQLTSRVEALQPVQ 340
SK K +LEKE+T +++S D + +K+L EE+V L + ++
Sbjct: 646 LETSKVTLKE--QQHQLEKELT----DQKSKLDQVLSKVLAAEERVRTLQEEERWCESLE 699
Query: 341 LELHEAKVKLSSVESQL 357
L + K +LS E QL
Sbjct: 700 KTLSQTKRQLSEREQQL 716
Score = 40.3 bits (90), Expect = 0.020
Identities = 61/268 (22%), Positives = 119/268 (44%), Gaps = 24/268 (8%)
Query: 105 QITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
Q +KL+ ++ + ++ L EEE+ SL + + +R +S+ E
Sbjct: 667 QKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 726
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+ E ++ + L+ + E+ KQ+A LK+ L K Q S+++K++ L Q
Sbjct: 727 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEAL-------KIQRSQLEKNL--LEQK 777
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
E + + EM ELV Q + E+ +L +L + +E+ T K++ ++D + Q
Sbjct: 778 QENSCIQKEMATIELVAQDNH-ERARRLMKELNQMQYEY---TELKKQMANQKDLERR-Q 832
Query: 283 TQSKTAQKRLCNMAELEKEV-TRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ---P 338
+ A + L +E++ E+ T L+ + L + + + E+ L +E+L+ P
Sbjct: 833 MEISDAMRTL--KSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLP 890
Query: 339 VQLE--LHEAKVKLSSVESQLESWMSAA 364
+ E K+ S V E W A
Sbjct: 891 FTMNEGPFEEKLNFSQVHIMDEHWRGEA 918
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 52.0 bits (119), Expect = 6e-06
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 262 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 321
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 322 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 372
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 373 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 430
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 431 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI-- 488
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 489 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 534
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 535 -----EELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 589
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL---EKSLQGYRDLIAAHDP 502
E +Y+ +L+ EKE L + L R Q L E+ L ++ +
Sbjct: 590 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIE-- 647
Query: 503 HAHSKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHL 556
H +E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L
Sbjct: 648 --HRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 705
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
+ ++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 706 QQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 45.6 bits (103), Expect = 5e-04
Identities = 67/321 (20%), Positives = 125/321 (38%), Gaps = 14/321 (4%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+KE T+L +Q+ +++L N + +++ E L+ + E ++ K ++ K
Sbjct: 2203 EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2262
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
++ + Q Q+ F + ++E E E D + T+ + K + +E+
Sbjct: 2263 GLAIKESDAMSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEE 2320
Query: 301 EVTRLRANERSLR----DAICNKLLLEEQVHQLTSRVEALQPVQLEL-HEAKVKLSSVES 355
+ +R E + D C K EE++ QL +E LQ + + + S+
Sbjct: 2321 KNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE 2380
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ +S E AL +E+A LT+E+ +LK ER+
Sbjct: 2381 EADSLKHQLDVVIAEKL-ALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERE 2439
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ K+ + N K L V D+ L E + E G GS
Sbjct: 2440 -SVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDA----LKSLENQTYFKSFEENGKGS 2494
Query: 476 VALLSARVQQLEKSLQGYRDL 496
+ L R+ QLE ++ +DL
Sbjct: 2495 IINLETRLLQLESTVSA-KDL 2514
Score = 42.7 bits (96), Expect = 0.004
Identities = 31/110 (28%), Positives = 63/110 (57%), Gaps = 7/110 (6%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS--EMKKDMDELLQALEGAQSEVEML 233
+K N ++E L++ I L+ +L AN+ K ++ + ++ D L L+ +E L
Sbjct: 2342 VKRNREEEIEQLNEVIEKLQQEL--ANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLAL 2399
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
++++ +T+ E+ T +KN L++ NF+ Q+T +L L+ ER+S + Q+
Sbjct: 2400 EQQV--ETAN-EEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQS 2446
Score = 42.3 bits (95), Expect = 0.005
Identities = 59/288 (20%), Positives = 130/288 (45%), Gaps = 27/288 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
++++L + K + T+L+ +++ + + E++ + K L K + + ++E
Sbjct: 3137 MQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLE 3196
Query: 155 XXXXXXXX---KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVS---NKDQ 208
D + K+ ++L+ +KEK L + K++L + S K +
Sbjct: 3197 VKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQR 3256
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSK 267
++ +++ Q L +Q ++E + Q S + + +L+ LE + ++++S
Sbjct: 3257 NLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSST 3316
Query: 268 LKELEYERDSYKDWQTQSKTAQKR--LCN---MAELEKE--------VTRLRANERSLRD 314
L + ER+ + Q+ T Q R L + + EL+K+ V L E+ D
Sbjct: 3317 L---DRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLD 3373
Query: 315 AICNKLLLEE--QVHQLTSRVE--ALQPVQLELHEAKVKLSSVESQLE 358
++ + +E+ QVH+ T + E A Q ++HE + K+ ++ QLE
Sbjct: 3374 SLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLE 3421
Score = 41.9 bits (94), Expect = 0.006
Identities = 84/424 (19%), Positives = 187/424 (44%), Gaps = 37/424 (8%)
Query: 210 SEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF-EFQQVTSK 267
+E+ + +EL+ + Q+ VE L + + + +S+ E + +L +++F + Q+ T
Sbjct: 1834 TEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATES 1893
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL-----L 322
LK E R+ + +S+ ++ +++ E + A+E++L + + L
Sbjct: 1894 LKCQEELRERLHE---ESRAREQLAVELSKAEGVIDGY-ADEKTLFERQIQEKTDIIDRL 1949
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGV-ESAGALRDALES 381
E+++ ++R++ L+ Q ++ E + LS + +++ + E+ +++ LE
Sbjct: 1950 EQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV 2009
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ E+V+ ++ E++K T +L DL + E + +++K
Sbjct: 2010 QCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT-ELMDLRQQNQALEKQLEKMRK 2068
Query: 441 RL--LLVTRE--RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
L + RE RD ++Q++ E++L V R Q + + +
Sbjct: 2069 FLDEQAIDREHERDVFQQEIQKLEQQLKVV--------------PRFQPISEHQTREVEQ 2114
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASLERIGPQTKVLH 555
+A H K E L ++ R+ E ++ KL + R+L A L KV
Sbjct: 2115 LANHLKEKTDKCSELLLSKEQLQRDIQE-RNEEIEKLEFRVRELEQALLVSADTFQKVED 2173
Query: 556 LTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRY 615
+ A EA+ ++S E++ E + + +E E+L+Q R++LEN ++++
Sbjct: 2174 RKHFGAVEAKPELSLEVQLQAE---RDAIDRKEKEITNLEEQLEQFREELENKNEEVQQL 2230
Query: 616 SIVL 619
+ L
Sbjct: 2231 HMQL 2234
Score = 41.9 bits (94), Expect = 0.006
Identities = 67/278 (24%), Positives = 122/278 (43%), Gaps = 32/278 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + ++++ ++ L + + +E+Q E+EKA L +RD+ + D++
Sbjct: 3189 ELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK- 3247
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHK-----QIADLKDKLLEANV-- 203
+ N ++ K L N ++K + + Q+++ + + LE V
Sbjct: 3248 ---FSLESQKQRNLQLNLLLEQQKQL-LNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 3303
Query: 204 -SNKDQISEMKKDMD---EL---LQALEG-AQSE----VEMLKKELVKQ-TSRAEQCTQL 250
S K +I EM +D EL LQ+ +G QS E L KEL KQ + + +L
Sbjct: 3304 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVEL 3363
Query: 251 KNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
N+ EK + Q ++ K+ + R + + Q + QK+ M EL+ +V L+
Sbjct: 3364 LNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK---MHELQSKVEDLQRQL 3420
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
R + KL LE Q +L ++ Q +LE E +
Sbjct: 3421 EEKRQQV-YKLDLEGQ--RLQGIMQEFQKQELEREEKR 3455
Score = 40.7 bits (91), Expect = 0.015
Identities = 80/372 (21%), Positives = 148/372 (39%), Gaps = 42/372 (11%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ----TSRAEQCTQLKN 252
+L+ + K + +E K +EL + L E L EL K A++ T +
Sbjct: 1878 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1937
Query: 253 QLEKQ-------NFEFQQVTSKLKELEYERDSYKDWQ---TQSKTA---------QKRLC 293
Q++++ E +++L+ELE E+ ++ + ++ K A Q+ L
Sbjct: 1938 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 1997
Query: 294 NMAELEKEVTRLRANERSLRDAICNKL-LLEEQVHQLTSR-VEALQPVQLELHEAKVKLS 351
+L KE ++ +RD + ++ LE V + SR +E Q EL + + +
Sbjct: 1998 ETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQ 2057
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++E QLE ++ RD + + H T EV L
Sbjct: 2058 ALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLA 2116
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV---TLC 468
+ T K ++L ++E L +Q+R E + ++ E+ L V T
Sbjct: 2117 NHLKEKTDKCSELLL---SKEQLQRDIQER----NEEIEKLEFRVRELEQALLVSADTFQ 2169
Query: 469 GEEGAGSVALLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGAR 527
E + A+ + LE LQ RD I + K + +L ++ ++REE E
Sbjct: 2170 KVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKE-----KEITNLEEQLEQFREELENKN 2224
Query: 528 RDVTKLRTQRDL 539
+V +L Q ++
Sbjct: 2225 EEVQQLHMQLEI 2236
Score = 35.9 bits (79), Expect = 0.43
Identities = 38/181 (20%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+ E+T++ + + L++ L +++S +ISE++ + E+ +L + +VE+ +K +++
Sbjct: 2581 EPERTNI-QNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLE 2639
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ + + +L EK+ E ++ S +++E + + + + + ++ E
Sbjct: 2640 KEKKLLELQKLLEGNEKKQREKEKKRSP-QDVEVLKTTTELFHSNEESGFFNELEALRAE 2698
Query: 300 KEVTRLR-ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
T+ A+ + + + +LL++E +TS + L V+ L EAK KLS +E + E
Sbjct: 2699 SVATKAELASYKEKAEKLQEELLVKET--NMTSLQKDLSQVRDHLAEAKEKLSILEKEDE 2756
Query: 359 S 359
+
Sbjct: 2757 T 2757
Score = 35.5 bits (78), Expect = 0.56
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN-- 252
KDK S D+IS D L E ++E +++ELV+Q +Q T+L
Sbjct: 1556 KDKTFIVRQSIHDEISVSSMDASRQLMLNE---EQLEDMRQELVRQYQEHQQATELLRQA 1612
Query: 253 ---QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q+E+Q + +Q+ ++K L + ++ +++ + ELE
Sbjct: 1613 HMPQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELE 1662
Score = 34.3 bits (75), Expect = 1.3
Identities = 37/176 (21%), Positives = 83/176 (47%), Gaps = 9/176 (5%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE-----VEMLKKEL 237
E + +Q+ +KL++ + + Q +++ D+ + ++ALE E +E+ +++
Sbjct: 1987 EAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKN 2046
Query: 238 VKQTSRAEQCTQLKNQLEK-QNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+ +Q L+ QLEK + F +Q + E + + + + Q K +
Sbjct: 2047 TELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISE 2106
Query: 297 ELEKEVTRLRANERSLRDAICNKLLL-EEQVHQ-LTSRVEALQPVQLELHEAKVKL 350
+EV +L AN + C++LLL +EQ+ + + R E ++ ++ + E + L
Sbjct: 2107 HQTREVEQL-ANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQAL 2161
Score = 33.1 bits (72), Expect = 3.0
Identities = 56/285 (19%), Positives = 123/285 (43%), Gaps = 28/285 (9%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXX 160
A + Q+ K+ ++ Q R+ + +F++E L +Q K R E
Sbjct: 2058 ALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN 2117
Query: 161 XXKDEFNTAAK---EHKDLKANWDKEKTDLHK---QIADLKDKLLEA-----NVSNKDQI 209
K++ + ++ + L+ + + ++ K ++ +L+ LL + V ++
Sbjct: 2118 HLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHF 2177
Query: 210 SEMKKDMDELLQA-LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV---- 264
++ + L+ L+ + ++ +KE+ T+ EQ Q + +LE +N E QQ+
Sbjct: 2178 GAVEAKPELSLEVQLQAERDAIDRKEKEI---TNLEEQLEQFREELENKNEEVQQLHMQL 2234
Query: 265 -------TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAIC 317
T++L+ELE E +KD + A K M+ ++ V + +++
Sbjct: 2235 EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVL-FGKFAQIIQEKEV 2293
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
L EQV +L +++ ++ + E + +E+Q+E MS
Sbjct: 2294 EIDQLNEQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMS 2337
Score = 32.3 bits (70), Expect = 5.3
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 13/252 (5%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
D+ A +I++LES+V HT ++ E+E+ + E++ E+ +E
Sbjct: 2601 DISALTLRISELESQVVEMHT-----SLILEKEQVEIAEKNVL-EKEKKLLELQKLLEGN 2654
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+ E + ++ + LK + ++ + + L +V+ K +++ K+ +
Sbjct: 2655 EKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAE 2714
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+L + L ++ + L+K+L + + + + LEK+ + +V K +E
Sbjct: 2715 KLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKE--DETEVQESKKACMFEPLP 2772
Query: 278 YK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
K S+T + + ++ A + + C+ + E + Q T ++E +
Sbjct: 2773 IKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKM 2832
Query: 337 QPVQLELHEAKV 348
Q ELH A++
Sbjct: 2833 Q----ELHAAEI 2840
Score = 31.9 bits (69), Expect = 6.9
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA-VSDMEDXXXXXXXXXXXX-KDEFN 167
ES+ +R ++ EEE + L E + + R + ++D ++E +
Sbjct: 616 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMS 675
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
+ + K N ++ L +I+ LKD L ++ V++K + EM ++EL Q
Sbjct: 676 QKIETMQFEKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------Q 725
Query: 228 SEVEMLK-KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQT 283
E+E+L+ +E K T E Q QLK + LEKQ E + + K +LE E KD +
Sbjct: 726 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EK 784
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
++ ++ E+ + L + + +D++ K +L+EE
Sbjct: 785 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 828
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 52.0 bits (119), Expect = 6e-06
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 274 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 333
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 334 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 384
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 385 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 442
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 443 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI-- 500
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 501 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 546
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 547 -----EELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 601
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL---EKSLQGYRDLIAAHDP 502
E +Y+ +L+ EKE L + L R Q L E+ L ++ +
Sbjct: 602 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIE-- 659
Query: 503 HAHSKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHL 556
H +E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L
Sbjct: 660 --HRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 717
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
+ ++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 718 QQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 768
Score = 45.6 bits (103), Expect = 5e-04
Identities = 67/321 (20%), Positives = 125/321 (38%), Gaps = 14/321 (4%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+KE T+L +Q+ +++L N + +++ E L+ + E ++ K ++ K
Sbjct: 2214 EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2273
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
++ + Q Q+ F + ++E E E D + T+ + K + +E+
Sbjct: 2274 GLAIKESDAMSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEE 2331
Query: 301 EVTRLRANERSLR----DAICNKLLLEEQVHQLTSRVEALQPVQLEL-HEAKVKLSSVES 355
+ +R E + D C K EE++ QL +E LQ + + + S+
Sbjct: 2332 KNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE 2391
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ +S E AL +E+A LT+E+ +LK ER+
Sbjct: 2392 EADSLKHQLDVVIAEKL-ALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERE 2450
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
+ K+ + N K L V D+ L E + E G GS
Sbjct: 2451 -SVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDA----LKSLENQTYFKSFEENGKGS 2505
Query: 476 VALLSARVQQLEKSLQGYRDL 496
+ L R+ QLE ++ +DL
Sbjct: 2506 IINLETRLLQLESTVSA-KDL 2525
Score = 42.7 bits (96), Expect = 0.004
Identities = 31/110 (28%), Positives = 63/110 (57%), Gaps = 7/110 (6%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS--EMKKDMDELLQALEGAQSEVEML 233
+K N ++E L++ I L+ +L AN+ K ++ + ++ D L L+ +E L
Sbjct: 2353 VKRNREEEIEQLNEVIEKLQQEL--ANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLAL 2410
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
++++ +T+ E+ T +KN L++ NF+ Q+T +L L+ ER+S + Q+
Sbjct: 2411 EQQV--ETAN-EEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQS 2457
Score = 42.3 bits (95), Expect = 0.005
Identities = 59/288 (20%), Positives = 130/288 (45%), Gaps = 27/288 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
++++L + K + T+L+ +++ + + E++ + K L K + + ++E
Sbjct: 3140 MQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLE 3199
Query: 155 XXXXXXXX---KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVS---NKDQ 208
D + K+ ++L+ +KEK L + K++L + S K +
Sbjct: 3200 VKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQR 3259
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSK 267
++ +++ Q L +Q ++E + Q S + + +L+ LE + ++++S
Sbjct: 3260 NLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSST 3319
Query: 268 LKELEYERDSYKDWQTQSKTAQKR--LCN---MAELEKE--------VTRLRANERSLRD 314
L + ER+ + Q+ T Q R L + + EL+K+ V L E+ D
Sbjct: 3320 L---DRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLD 3376
Query: 315 AICNKLLLEE--QVHQLTSRVE--ALQPVQLELHEAKVKLSSVESQLE 358
++ + +E+ QVH+ T + E A Q ++HE + K+ ++ QLE
Sbjct: 3377 SLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLE 3424
Score = 41.9 bits (94), Expect = 0.006
Identities = 84/424 (19%), Positives = 187/424 (44%), Gaps = 37/424 (8%)
Query: 210 SEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF-EFQQVTSK 267
+E+ + +EL+ + Q+ VE L + + + +S+ E + +L +++F + Q+ T
Sbjct: 1845 TEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATES 1904
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL-----L 322
LK E R+ + +S+ ++ +++ E + A+E++L + + L
Sbjct: 1905 LKCQEELRERLHE---ESRAREQLAVELSKAEGVIDGY-ADEKTLFERQIQEKTDIIDRL 1960
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGV-ESAGALRDALES 381
E+++ ++R++ L+ Q ++ E + LS + +++ + E+ +++ LE
Sbjct: 1961 EQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV 2020
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ E+V+ ++ E++K T +L DL + E + +++K
Sbjct: 2021 QCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT-ELMDLRQQNQALEKQLEKMRK 2079
Query: 441 RL--LLVTRE--RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
L + RE RD ++Q++ E++L V R Q + + +
Sbjct: 2080 FLDEQAIDREHERDVFQQEIQKLEQQLKVV--------------PRFQPISEHQTREVEQ 2125
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQ-RDLLTASLERIGPQTKVLH 555
+A H K E L ++ R+ E ++ KL + R+L A L KV
Sbjct: 2126 LANHLKEKTDKCSELLLSKEQLQRDIQE-RNEEIEKLEFRVRELEQALLVSADTFQKVED 2184
Query: 556 LTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRY 615
+ A EA+ ++S E++ E + + +E E+L+Q R++LEN ++++
Sbjct: 2185 RKHFGAVEAKPELSLEVQLQAE---RDAIDRKEKEITNLEEQLEQFREELENKNEEVQQL 2241
Query: 616 SIVL 619
+ L
Sbjct: 2242 HMQL 2245
Score = 41.9 bits (94), Expect = 0.006
Identities = 67/278 (24%), Positives = 122/278 (43%), Gaps = 32/278 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + ++++ ++ L + + +E+Q E+EKA L +RD+ + D++
Sbjct: 3192 ELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK- 3250
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHK-----QIADLKDKLLEANV-- 203
+ N ++ K L N ++K + + Q+++ + + LE V
Sbjct: 3251 ---FSLESQKQRNLQLNLLLEQQKQL-LNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 3306
Query: 204 -SNKDQISEMKKDMD---EL---LQALEG-AQSE----VEMLKKELVKQ-TSRAEQCTQL 250
S K +I EM +D EL LQ+ +G QS E L KEL KQ + + +L
Sbjct: 3307 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVEL 3366
Query: 251 KNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
N+ EK + Q ++ K+ + R + + Q + QK+ M EL+ +V L+
Sbjct: 3367 LNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK---MHELQSKVEDLQRQL 3423
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
R + KL LE Q +L ++ Q +LE E +
Sbjct: 3424 EEKRQQV-YKLDLEGQ--RLQGIMQEFQKQELEREEKR 3458
Score = 40.7 bits (91), Expect = 0.015
Identities = 80/372 (21%), Positives = 148/372 (39%), Gaps = 42/372 (11%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ----TSRAEQCTQLKN 252
+L+ + K + +E K +EL + L E L EL K A++ T +
Sbjct: 1889 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1948
Query: 253 QLEKQ-------NFEFQQVTSKLKELEYERDSYKDWQ---TQSKTA---------QKRLC 293
Q++++ E +++L+ELE E+ ++ + ++ K A Q+ L
Sbjct: 1949 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 2008
Query: 294 NMAELEKEVTRLRANERSLRDAICNKL-LLEEQVHQLTSR-VEALQPVQLELHEAKVKLS 351
+L KE ++ +RD + ++ LE V + SR +E Q EL + + +
Sbjct: 2009 ETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQ 2068
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++E QLE ++ RD + + H T EV L
Sbjct: 2069 ALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLA 2127
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV---TLC 468
+ T K ++L ++E L +Q+R E + ++ E+ L V T
Sbjct: 2128 NHLKEKTDKCSELLL---SKEQLQRDIQER----NEEIEKLEFRVRELEQALLVSADTFQ 2180
Query: 469 GEEGAGSVALLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGAR 527
E + A+ + LE LQ RD I + K + +L ++ ++REE E
Sbjct: 2181 KVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKE-----KEITNLEEQLEQFREELENKN 2235
Query: 528 RDVTKLRTQRDL 539
+V +L Q ++
Sbjct: 2236 EEVQQLHMQLEI 2247
Score = 35.9 bits (79), Expect = 0.43
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL---- 250
KDK S D+IS D L E ++E +++ELV+Q +Q T+L
Sbjct: 1567 KDKTFIVRQSIHDEISVSSMDASRQLMLNE---EQLEDMRQELVRQYQEHQQATELLRQA 1623
Query: 251 -KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q+E+Q + +Q+ ++K L + ++ +++ + ELE
Sbjct: 1624 HMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELE 1673
Score = 35.9 bits (79), Expect = 0.43
Identities = 38/181 (20%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+ E+T++ + + L++ L +++S +ISE++ + E+ +L + +VE+ +K +++
Sbjct: 2592 EPERTNI-QNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLE 2650
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ + + +L EK+ E ++ S +++E + + + + + ++ E
Sbjct: 2651 KEKKLLELQKLLEGNEKKQREKEKKRSP-QDVEVLKTTTELFHSNEESGFFNELEALRAE 2709
Query: 300 KEVTRLR-ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
T+ A+ + + + +LL++E +TS + L V+ L EAK KLS +E + E
Sbjct: 2710 SVATKAELASYKEKAEKLQEELLVKET--NMTSLQKDLSQVRDHLAEAKEKLSILEKEDE 2767
Query: 359 S 359
+
Sbjct: 2768 T 2768
Score = 34.3 bits (75), Expect = 1.3
Identities = 37/176 (21%), Positives = 83/176 (47%), Gaps = 9/176 (5%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE-----VEMLKKEL 237
E + +Q+ +KL++ + + Q +++ D+ + ++ALE E +E+ +++
Sbjct: 1998 EAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKN 2057
Query: 238 VKQTSRAEQCTQLKNQLEK-QNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+ +Q L+ QLEK + F +Q + E + + + + Q K +
Sbjct: 2058 TELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISE 2117
Query: 297 ELEKEVTRLRANERSLRDAICNKLLL-EEQVHQ-LTSRVEALQPVQLELHEAKVKL 350
+EV +L AN + C++LLL +EQ+ + + R E ++ ++ + E + L
Sbjct: 2118 HQTREVEQL-ANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQAL 2172
Score = 33.1 bits (72), Expect = 3.0
Identities = 56/285 (19%), Positives = 123/285 (43%), Gaps = 28/285 (9%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXX 160
A + Q+ K+ ++ Q R+ + +F++E L +Q K R E
Sbjct: 2069 ALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN 2128
Query: 161 XXKDEFNTAAK---EHKDLKANWDKEKTDLHK---QIADLKDKLLEA-----NVSNKDQI 209
K++ + ++ + L+ + + ++ K ++ +L+ LL + V ++
Sbjct: 2129 HLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHF 2188
Query: 210 SEMKKDMDELLQA-LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV---- 264
++ + L+ L+ + ++ +KE+ T+ EQ Q + +LE +N E QQ+
Sbjct: 2189 GAVEAKPELSLEVQLQAERDAIDRKEKEI---TNLEEQLEQFREELENKNEEVQQLHMQL 2245
Query: 265 -------TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAIC 317
T++L+ELE E +KD + A K M+ ++ V + +++
Sbjct: 2246 EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVL-FGKFAQIIQEKEV 2304
Query: 318 NKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMS 362
L EQV +L +++ ++ + E + +E+Q+E MS
Sbjct: 2305 EIDQLNEQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMS 2348
Score = 32.3 bits (70), Expect = 5.3
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 13/252 (5%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
D+ A +I++LES+V HT ++ E+E+ + E++ E+ +E
Sbjct: 2612 DISALTLRISELESQVVEMHT-----SLILEKEQVEIAEKNVL-EKEKKLLELQKLLEGN 2665
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+ E + ++ + LK + ++ + + L +V+ K +++ K+ +
Sbjct: 2666 EKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAE 2725
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+L + L ++ + L+K+L + + + + LEK+ + +V K +E
Sbjct: 2726 KLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKE--DETEVQESKKACMFEPLP 2783
Query: 278 YK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
K S+T + + ++ A + + C+ + E + Q T ++E +
Sbjct: 2784 IKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKM 2843
Query: 337 QPVQLELHEAKV 348
Q ELH A++
Sbjct: 2844 Q----ELHAAEI 2851
Score = 31.9 bits (69), Expect = 6.9
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA-VSDMEDXXXXXXXXXXXX-KDEFN 167
ES+ +R ++ EEE + L E + + R + ++D ++E +
Sbjct: 628 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMS 687
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
+ + K N ++ L +I+ LKD L ++ V++K + EM ++EL Q
Sbjct: 688 QKIETMQFEKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------Q 737
Query: 228 SEVEMLK-KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQT 283
E+E+L+ +E K T E Q QLK + LEKQ E + + K +LE E KD +
Sbjct: 738 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EK 796
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
++ ++ E+ + L + + +D++ K +L+EE
Sbjct: 797 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 840
>AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein.
Length = 2073
Score = 52.0 bits (119), Expect = 6e-06
Identities = 100/458 (21%), Positives = 186/458 (40%), Gaps = 33/458 (7%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQISEMKKDMDELL--Q 221
K A K +L KQI++LK K L + N N++++ E+ + + E+L +
Sbjct: 1545 KQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQK 1604
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
E S +E ++E E+C Q + E +V + ++ E KD
Sbjct: 1605 EKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKD 1664
Query: 281 WQTQSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
+ + R ++++ +++++ L NE+ L++ K L E+++ ++ +
Sbjct: 1665 -ELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSEELNSCVDKLAKSSLL 1719
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ + K + S E Q S S A E L D +++
Sbjct: 1720 EHRIATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQE 1778
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER-DSYRQQLDC 458
L +EV +L + A GK S +H QKRL + + QQL
Sbjct: 1779 KEALKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLW 1836
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAAHDPHAHSKALESLRN 514
E E + T+ +E + +V+QLE +L Q + + +P K SL+
Sbjct: 1837 QENERSQTMV-QEHQSRLTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKL--SLKR 1893
Query: 515 EVTRWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
E ++++E A R V+++ + +++L T LE G + K + L + E Q S
Sbjct: 1894 ECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL-DEQLMEMQHLRSTATP 1952
Query: 574 AAQEEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
+ L++ ++ E+ LQ RQ L+ RI
Sbjct: 1953 SPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 1990
Score = 42.3 bits (95), Expect = 0.005
Identities = 55/255 (21%), Positives = 110/255 (43%), Gaps = 25/255 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1698 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1756
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANV------- 203
K + +E + LK +E LHKQ+ + K +
Sbjct: 1757 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1812
Query: 204 -SNKDQISEMKKD--MDELLQAL--EGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQN 258
+ + ++S K D M+E Q L E +S+ M+++ + T E+ QL++ L ++
Sbjct: 1813 HNQQKRLSWDKLDHLMNEEQQLLWQENERSQT-MVQEHQSRLTHSREKVRQLESNLLPKH 1871
Query: 259 FEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
+ + + E E+ S K +Q + A +++ M LE+E+ + L+
Sbjct: 1872 QKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKK 1931
Query: 315 AICNKLLLEEQVHQL 329
++ L+EQ+ ++
Sbjct: 1932 ---KQVKLDEQLMEM 1943
Score = 39.5 bits (88), Expect = 0.035
Identities = 38/172 (22%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 632 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 687
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 688 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 747
Query: 287 TAQKRLCNMAE---LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
Q++L ++ E LEKE R E+ R+ + +E + ++ TS++EA
Sbjct: 748 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEA 799
Score = 36.3 bits (80), Expect = 0.32
Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 42/296 (14%)
Query: 119 IRKEMQILFEEEKASLIEQH--KRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKE---- 172
+ +E++ +E+ SL+E+H +++E +E + E N +
Sbjct: 741 LTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQ 800
Query: 173 -HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
D + ++ ++ L + +L + +++ S+ + + DEL Q AQ E
Sbjct: 801 FQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQ---E 857
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEF--------QQVTSKLKEL----EYERDSYK 279
+LK+ L ++ + + TQ + LEK E QQ+ L++L E ++
Sbjct: 858 LLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSMLS 917
Query: 280 DWQTQSKTAQKR--------LCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVH 327
D + K++ KR LC E+ + RL R + +KLL E +H
Sbjct: 918 DQILELKSSHKRELREREEVLCQAGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 977
Query: 328 QLT----SRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
+ T R A ++ ++K+K +S S L++ VE GAL
Sbjct: 978 KATCETADRERAEMSTEISRLQSKIKEMQQATSPLSMLQNGCQVIGEEEVEGDGAL 1033
Score = 33.5 bits (73), Expect = 2.3
Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 24/173 (13%)
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTSRAEQCTQLKNQ--LE 255
A S K +I + + +D++++ E +S++ E LK + + + +N+ L
Sbjct: 361 ALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLR 420
Query: 256 KQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
K + E+++ + LK EL ER+ Q + ++RL ELE+E+ + + E +RD
Sbjct: 421 KLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELEQEIEKAKTEENYIRD 471
Query: 315 AICNKL---------LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ L LLE + L + L P E + +L+ + ++ E
Sbjct: 472 RLALSLKENSRLENELLENAENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYE 524
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 52.0 bits (119), Expect = 6e-06
Identities = 91/391 (23%), Positives = 151/391 (38%), Gaps = 34/391 (8%)
Query: 2 AKESDMSLYSDVLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSS 61
AK S + P R T PK AST + + S+ G S + G+ SS
Sbjct: 109 AKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSL----GPSGSASAGELSSS 164
Query: 62 IGSVDDVTPDKR--LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTI 119
S TP + + PP P +K + +AQ+ LE ++
Sbjct: 165 EPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEE----GLRAQVRDLEEKLETLRLK 220
Query: 120 RKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKAN 179
R E ++ K +E+HK V + + E AKE + K
Sbjct: 221 RAE-----DKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER 275
Query: 180 WDKEKTDLHKQI--ADLKDKLLEANVSNKDQ-ISEMKKDMDELLQALEGAQSEVEMLKKE 236
+ +E D I A L ++ E + Q + +K+ +DEL LE ++E+E
Sbjct: 276 YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE---- 331
Query: 237 LVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL-EYERDSYKDWQTQSKTAQKRL--- 292
K + A QLK QLE+QN + ++++L E+ + Q + + L
Sbjct: 332 --KGSDGAASSYQLK-QLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVV 388
Query: 293 -CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
L++E+++ + L++ + L EE V LT R L+ EL E L
Sbjct: 389 RQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLE 448
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESA 382
++ + AR +E LR+ L+ A
Sbjct: 449 AMNEMNDELQENARETELE----LREQLDMA 475
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 52.0 bits (119), Expect = 6e-06
Identities = 91/391 (23%), Positives = 151/391 (38%), Gaps = 34/391 (8%)
Query: 2 AKESDMSLYSDVLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSS 61
AK S + P R T PK AST + + S+ G S + G+ SS
Sbjct: 126 AKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGASSSL----GPSGSASAGELSSS 181
Query: 62 IGSVDDVTPDKR--LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTI 119
S TP + + PP P +K + +AQ+ LE ++
Sbjct: 182 EPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEE----GLRAQVRDLEEKLETLRLK 237
Query: 120 RKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKAN 179
R E ++ K +E+HK V + + E AKE + K
Sbjct: 238 RAE-----DKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKER 292
Query: 180 WDKEKTDLHKQI--ADLKDKLLEANVSNKDQ-ISEMKKDMDELLQALEGAQSEVEMLKKE 236
+ +E D I A L ++ E + Q + +K+ +DEL LE ++E+E
Sbjct: 293 YMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE---- 348
Query: 237 LVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL-EYERDSYKDWQTQSKTAQKRL--- 292
K + A QLK QLE+QN + ++++L E+ + Q + + L
Sbjct: 349 --KGSDGAASSYQLK-QLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVV 405
Query: 293 -CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
L++E+++ + L++ + L EE V LT R L+ EL E L
Sbjct: 406 RQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLE 465
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESA 382
++ + AR +E LR+ L+ A
Sbjct: 466 AMNEMNDELQENARETELE----LREQLDMA 492
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 52.0 bits (119), Expect = 6e-06
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 274 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 333
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 334 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 384
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 385 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 442
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 443 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI-- 500
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 501 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 546
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 547 -----EELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 601
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL---EKSLQGYRDLIAAHDP 502
E +Y+ +L+ EKE L + L R Q L E+ L ++ +
Sbjct: 602 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIE-- 659
Query: 503 HAHSKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHL 556
H +E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L
Sbjct: 660 --HRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 717
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
+ ++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 718 QQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 768
Score = 31.9 bits (69), Expect = 6.9
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA-VSDMEDXXXXXXXXXXXX-KDEFN 167
ES+ +R ++ EEE + L E + + R + ++D ++E +
Sbjct: 628 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMS 687
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
+ + K N ++ L +I+ LKD L ++ V++K + EM ++EL Q
Sbjct: 688 QKIETMQFEKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------Q 737
Query: 228 SEVEMLK-KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQT 283
E+E+L+ +E K T E Q QLK + LEKQ E + + K +LE E KD +
Sbjct: 738 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EK 796
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
++ ++ E+ + L + + +D++ K +L+EE
Sbjct: 797 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 840
Score = 31.9 bits (69), Expect = 6.9
Identities = 22/74 (29%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
KDK S D+IS D L E ++E +++ELV+Q +Q T+L Q
Sbjct: 1567 KDKTFIVRQSIHDEISVSSMDASRQLMLNE---EQLEDMRQELVRQYQEHQQATELLRQA 1623
Query: 255 EKQNFEFQQVTSKL 268
E Q+ +L
Sbjct: 1624 HMPQMERQREDQEL 1637
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 52.0 bits (119), Expect = 6e-06
Identities = 105/531 (19%), Positives = 217/531 (40%), Gaps = 58/531 (10%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 243 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 302
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 303 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 353
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 354 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 411
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 412 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI-- 469
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 470 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 515
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 516 -----EELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 570
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL---EKSLQGYRDLIAAHDP 502
E +Y+ +L+ EKE L + L R Q L E+ L ++ +
Sbjct: 571 EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIE-- 628
Query: 503 HAHSKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHL 556
H +E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L
Sbjct: 629 --HRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDL 686
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
+ ++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 687 QQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 737
Score = 33.5 bits (73), Expect = 2.3
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL---- 250
KDK S D+IS D L E ++E +++ELV+Q +Q T+L
Sbjct: 1536 KDKTFIVRQSIHDEISVSSMDASRQLMLNE---EQLEDMRQELVRQYQEHQQATELLRQA 1592
Query: 251 -KNQLEKQNFEFQQVTSKLKEL 271
Q+E+Q + +Q+ ++K L
Sbjct: 1593 HMRQMERQREDQEQLQEEIKRL 1614
Score = 31.9 bits (69), Expect = 6.9
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 20/224 (8%)
Query: 110 ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERA-VSDMEDXXXXXXXXXXXX-KDEFN 167
ES+ +R ++ EEE + L E + + R + ++D ++E +
Sbjct: 597 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMS 656
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQ 227
+ + K N ++ L +I+ LKD L ++ V++K + EM ++EL Q
Sbjct: 657 QKIETMQFEKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------Q 706
Query: 228 SEVEMLK-KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQT 283
E+E+L+ +E K T E Q QLK + LEKQ E + + K +LE E KD +
Sbjct: 707 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EK 765
Query: 284 QSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
++ ++ E+ + L + + +D++ K +L+EE
Sbjct: 766 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 809
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 51.6 bits (118), Expect = 8e-06
Identities = 117/547 (21%), Positives = 221/547 (40%), Gaps = 69/547 (12%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAV----S 146
+ K++++DL AK KLE + + +E + E +K L E+ K+ E + S
Sbjct: 1042 QEKKVRMDLERAKR---KLEGDLK----LTQESIMDLENDKLQLEEKLKKKEFDINQQNS 1094
Query: 147 DMEDXXXXXXXXXXXXKD------EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE 200
+ED K+ E + + +A +K ++DL +++ ++ ++L E
Sbjct: 1095 KIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1154
Query: 201 ANVSNKDQISEMKK---DMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
A + QI KK + ++ + LE A + E L K+ A+ +L Q++
Sbjct: 1155 AGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK--HADSVAELGEQIDNL 1212
Query: 258 NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRAN----ERSL 312
Q++ + E + E D Q A+ L ++ LE + R +RSL
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
Query: 313 RDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV----KLSSVESQLESWMSA--ARA 366
D + L+ + +L ++E + + +L K+ ++ ++ QLE A A A
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 367 HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTT 426
H ++SA D L + T KYE D A + +L
Sbjct: 1333 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT-KYETD-AIQRTEELEE 1390
Query: 427 VRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQL 486
+K + ++ + V + S + + E+ + E + + A L
Sbjct: 1391 AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA------L 1444
Query: 487 EKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLER 546
+K + + ++A + E ++E+ ++EA ++ KL+ + SLE
Sbjct: 1445 DKKQRNFDKILAEW-----KQKYEESQSELESSQKEARSLSTELFKLKNAYE---ESLE- 1495
Query: 547 IGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLE 606
HL E K+ +K L QEEI L L EGG EL+++R+QLE
Sbjct: 1496 --------HL------ETFKRENKNL---QEEISDLTEQLGEGGKNV--HELEKVRKQLE 1536
Query: 607 NSRIKLK 613
+++L+
Sbjct: 1537 VEKLELQ 1543
Score = 45.6 bits (103), Expect = 5e-04
Identities = 105/575 (18%), Positives = 228/575 (39%), Gaps = 67/575 (11%)
Query: 89 PWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDM 148
PW KI + A+ K T+++E + E + S + + +E+ VS +
Sbjct: 830 PWMKLYFKIKPLLKSAETEK------EMATMKEEFGRIKETLEKSEARRKELEEKMVSLL 883
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDL---KANWDKEKTDLHKQIADLKDKLLEANVSN 205
++ +D N A + L K + + ++++++ D ++ E
Sbjct: 884 QEKNDLQLQVQAE-QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKK 942
Query: 206 K---DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQ 262
+ D+ SE+KKD+D+L L + E + ++ T ++ +L K+ Q
Sbjct: 943 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQ 1002
Query: 263 QVTSK-LKELEYERDSYKDWQTQSKTAQKRLCNM---AELEKEVTR------------LR 306
+ + L +L+ E D ++++ ++ E EK+V L+
Sbjct: 1003 EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 307 ANERSLRDAICNKLLLEEQ-------VHQLTSRVEALQPVQLELH----EAKVKLSSVES 355
+ S+ D +KL LEE+ ++Q S++E Q + L+L E + ++ +E
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEE 1122
Query: 356 QLESWMSA-ARAHGVES-----AGALRDALESALGXXXXXXXXXXXXXXXXXHLTE--EV 407
+LE+ +A A+ + S + + LE A G + E
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Query: 408 ATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTL 467
ATL++E A + +V + E I LQ+ + +E+ ++ +LD + +
Sbjct: 1183 ATLQHEATAAALRKKHADSVAELGEQ-IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1241
Query: 468 CGEEGAGSVAL--------LSARVQQLEKSLQGYRDLIAAHDPHAHSKA-----LESLRN 514
+ V+ ++++ ++SL + A A E+L +
Sbjct: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIS 1301
Query: 515 EVTR----WREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISK 570
++TR + ++ E +R + + ++ L +L+ +L EA+ ++ +
Sbjct: 1302 QLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1361
Query: 571 ELEAAQEEIKKLKVALREGGAQADPEELQQMRQQL 605
L A E+ + + Q EEL++ +++L
Sbjct: 1362 VLSKANSEVAQWRTKYETDAIQR-TEELEEAKKKL 1395
Score = 41.9 bits (94), Expect = 0.006
Identities = 90/470 (19%), Positives = 193/470 (41%), Gaps = 36/470 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L K E + H T ++E + L +EE + L EQ + V ++E
Sbjct: 1475 EARSLSTELFKLK---NAYEESLEHLETFKRENKNL-QEEISDLTEQLGEGGKNVHELEK 1530
Query: 151 XXXXXXXXXXXXKD--EFNTAAKEHKD---LKAN--WDKEKTDLHKQIADLKDKLLEANV 203
+ E A+ EH++ L+A +++ K ++ +++A+ +++ +A
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Query: 204 SNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQ 262
+++ + ++ +D A +++EV +KK++ + E Q + + + +
Sbjct: 1591 NHQRVVDSLQTSLD----AETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1646
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI----CN 318
+ S LK+ + + D K N+A +E+ L+A LR + +
Sbjct: 1647 SLQSLLKDTQIQLDDAVRANDDLKE------NIAIVERRNNLLQAELEELRAVVEQTERS 1700
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA----RAHGVESAGA 374
+ L E+++ + + RV+ L L K K+ S +QL+S + A R ++ A
Sbjct: 1701 RKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKA 1760
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG-KLNDLTTVRKNQES 433
+ DA A ++ + + L++ D+A L + E+
Sbjct: 1761 ITDAAMMA-EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1819
Query: 434 LIHRLQKRL-LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQG 492
+ L+ L R +S + + +T EE ++ L V +L+ ++
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
Query: 493 YRDLIAAHDPHAHS--KALESLRNEVTRWREEAEGARRDVTKLRTQ-RDL 539
Y+ + A++ +++E+ E A+ A V KLR + RD+
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDI 1929
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/436 (18%), Positives = 174/436 (39%), Gaps = 26/436 (5%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
K LE ++ + + + ++ L+ +E + E K+ + LK+QLE
Sbjct: 482 KELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLE 541
Query: 256 ---KQNFEFQQVTSKLKELEYERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERS 311
K+N Q T K+ +L+ + D +T+S TA + AE K++ +L +N R
Sbjct: 542 DLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRD 601
Query: 312 LRDAIC----NKLLLEEQVHQLTSRVEALQPVQLE----LHEAKVKLSSVESQLESWMSA 363
L+D C KL LE++ L S +E+ + + +++ + ++ +E L++
Sbjct: 602 LQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKIL 661
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
+E + L +E A K + + K
Sbjct: 662 LAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKI 721
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD--CYEKELTVTLCGEEGAGSVALLSA 481
++ + + + ++K+LL E + +Q+++ E E +L + S ++
Sbjct: 722 YESIEEAKSEAMKEMEKKLL----EERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINE 777
Query: 482 RVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLT 541
++Q + + R+L + + L +N++ ++ + +L+ + + L
Sbjct: 778 LLKQKDVLNEDVRNLTLKIEQETQKRCL--TQNDLKMQTQQVNTLKMSEKQLKQENNHLM 835
Query: 542 ASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADP-----E 596
+ Q L A K++ +LEA Q K +RE + + +
Sbjct: 836 EMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGK 895
Query: 597 ELQQMRQQLENSRIKL 612
ELQQ +Q+L++ R L
Sbjct: 896 ELQQKKQELQDERDSL 911
Score = 42.3 bits (95), Expect = 0.005
Identities = 74/377 (19%), Positives = 166/377 (44%), Gaps = 31/377 (8%)
Query: 102 AKAQITK-LESRVNHQHTIRKEMQ-ILFEEEK-ASLIE-QHKRDERAVSDM--EDXXXXX 155
AK++ K +E ++ + T++++++ +L E EK SL++ K+ ++ ++++ +
Sbjct: 728 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNE 787
Query: 156 XXXXXXXKDEFNTAAK--EHKDLKANWDKEKT--DLHKQIADLKDKLLEANVSNKDQISE 211
K E T + DLK + T KQ+ + L+E ++ + Q +E
Sbjct: 788 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 847
Query: 212 MKKDMDELLQALEGAQSEVE-MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
++K+ Q +G E++ L+ E T Q +LK + E++ +++ K +E
Sbjct: 848 LRKER----QDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 903
Query: 271 LEYERDSYKDWQ--TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL--EEQV 326
L+ ERDS T +K ++L + E++ + L E+ +++ +++ ++++
Sbjct: 904 LQDERDSLAAQLEITLTKADSEQLAR-SIAEEQYSDLE-KEKIMKELEIKEMMARHKQEL 961
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXX 386
+ + + +L+ L L++ + +L + + + E L+D SA
Sbjct: 962 TEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ----EQLSRLKDEEISAAAIK 1017
Query: 387 XXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
++A + R + + ND RK +E+ +K + +
Sbjct: 1018 AQFEKQLLTERTLKTQAVNKLAEI-MNRKEPVKRGNDTDVRRKEKEN-----RKLHMELK 1071
Query: 447 RERDSYRQQLDCYEKEL 463
ER+ QQ+ Y+KEL
Sbjct: 1072 SEREKLTQQMIKYQKEL 1088
Score = 40.3 bits (90), Expect = 0.020
Identities = 36/195 (18%), Positives = 81/195 (41%), Gaps = 7/195 (3%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E+ A D K N + + L Q+ DLK + + +S ++++++++ +DE L
Sbjct: 514 EYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST-EKVNQLQRQLDETNALLR 572
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
L+K + + + +Q L+ +N + KL++ S + + +
Sbjct: 573 TESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERR 632
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+T + N +L+ + L E L++ +E + QL R L+ + +
Sbjct: 633 DRTHGSEIIN--DLQGRICGL---EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNME 687
Query: 345 -EAKVKLSSVESQLE 358
+ +L ++ LE
Sbjct: 688 IDMTYQLKVIQQSLE 702
Score = 36.7 bits (81), Expect = 0.24
Identities = 52/224 (23%), Positives = 100/224 (44%), Gaps = 33/224 (14%)
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+ +E+ +++ ++E ++ K++ L++ L SN+ Q E EL Q + +
Sbjct: 427 SCRENDSIQSRKNEESQEIQKKLYTLEEHL-----SNEMQAKE------ELEQKCKSVNT 475
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQ-------NFEFQQ----VTSKLKELEYE--- 274
+E KEL ++ + + QLE++ N E+Q+ K + LE +
Sbjct: 476 RLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNS 535
Query: 275 -RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD--AICNKLLLE--EQVHQL 329
+D +D + +++ +Q + +L++++ A R+ D A K E +Q+ QL
Sbjct: 536 LKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQL 595
Query: 330 TSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA---RAHGVE 370
S LQ L AK+KL L+S + + R HG E
Sbjct: 596 ESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSE 639
Score = 31.5 bits (68), Expect = 9.2
Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
LL + S ++ S + +E + + + E L E+ + ++C + +LEK
Sbjct: 421 LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT 480
Query: 258 NFEFQQ-------VTSKLKELEYERD--SYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN 308
E ++ V S L++LE E+ +K+ + Q K A LE +V L+
Sbjct: 481 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRK-ADHEADKKRNLENDVNSLKDQ 539
Query: 309 ERSLRDAICNKLLLEEQVHQLTSRVE 334
L+ N + E+V+QL +++
Sbjct: 540 LEDLKKRNQNSQISTEKVNQLQRQLD 565
>BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein
protein.
Length = 971
Score = 51.6 bits (118), Expect = 8e-06
Identities = 102/500 (20%), Positives = 218/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 185 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 243
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 244 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 298
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 299 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 348
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 349 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 408
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L++A +A+L+ +++
Sbjct: 409 QLQQELENLKEV-----LEDKLDTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 463
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 464 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 511
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 512 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 571
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E+ ++ +L+E
Sbjct: 572 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 631
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 632 VLAFQTMEEEKEKEQRALEN 651
Score = 46.4 bits (105), Expect = 3e-04
Identities = 56/289 (19%), Positives = 127/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 504 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 563
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 564 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 623
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 624 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGLRIEMEQEL 683
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 684 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 739
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ R+ L LHE +S++ +LE
Sbjct: 740 RQSKEHICRITDLQEELRHREHRISELDKEVQHLHE---NISALTKELE 785
Score = 38.7 bits (86), Expect = 0.060
Identities = 112/532 (21%), Positives = 209/532 (39%), Gaps = 63/532 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 316 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 375
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
K + + + +KD K N +++K L +++ +LK+ L + + +I
Sbjct: 376 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLDTANQEIGH 434
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKEL 271
++ + + Q L A+ + L+ Q + K+ L++ V EL
Sbjct: 435 LQDMVRKSEQGLGSAEGLIASLQD---SQERLQNELDLTKDSLKETKDALLNVEG---EL 488
Query: 272 EYERDSYKDWQTQSKTAQK-RLCNMA-ELEKEVTRLRANERSLRDAICNKLLLEEQV-HQ 328
E ER +++ K +K ++ MA +LE + T +LR C+KL E ++ H+
Sbjct: 489 EQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWT------ENLRQE-CSKLREELRLQHE 541
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG-XXX 387
+ Q +QL+ E S + ++E ++ L+ LE L
Sbjct: 542 EDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLN--------QISLLKQNLEIQLSQSQT 593
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTV---------RKNQESLIHRL 438
LT+E+ L+ + + L + + K Q +L + L
Sbjct: 594 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 653
Query: 439 -QKRLLLVTRERDSYRQQLDC----YEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
QK + +D++R+ ++ E+EL E G L S R +L
Sbjct: 654 QQKHSAELQSLKDAHRESMEGLRIEMEQELQTLRFELEDEGKAMLASLR-SELNHQHAAA 712
Query: 494 RDLIAAHDPHAHSKALESLRNEVTRWRE-EAEGARRDVTKLRTQRDLLTASLERIGPQTK 552
DL+ H H + L + + E+ R + ++ + ++ ++ L RI K
Sbjct: 713 IDLLR----HNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHRISELDK 768
Query: 553 -VLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQ 603
V HL N +A ++KELE +EI +++ + + EE MR+
Sbjct: 769 EVQHLHENISA-----LTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRE 815
Score = 35.1 bits (77), Expect = 0.75
Identities = 87/474 (18%), Positives = 186/474 (39%), Gaps = 28/474 (5%)
Query: 122 EMQILFEEEKASLIEQ----HKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLK 177
++Q+ FE++K +E H+R+ + + + +E + E + L
Sbjct: 54 QLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRM--EVESLN 111
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
++ + + K I D + KL +A + ++ +K+ ++L+ ++ + L+KE
Sbjct: 112 KMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEF 171
Query: 238 VKQTSRAEQCT-QLKNQLEKQNFEFQQVTSKLKELE----YERDSYKDWQTQSKTAQKRL 292
Q + + +LK +L+ E + K ++L+ ++ + Q Q A++
Sbjct: 172 QGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGE 231
Query: 293 CNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQL-ELHEAKVKLS 351
+ KEV A R + L+L+ + + Q V + +L K +++
Sbjct: 232 MALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVN 291
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
SQLE + R+ +L + + + + E+ L+
Sbjct: 292 ERLSQLEEERAFLRS----KTQSLDEEQKQQI--LELEKKVNEAKRTQQEYYERELKNLQ 345
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
++ +LN+ + + + H + + RD + Q+D E+ L EE
Sbjct: 346 SRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE 405
Query: 472 GAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
L ++ L++ L+ D A+ H + + + E + +D
Sbjct: 406 DKNQ---LQQELENLKEVLEDKLD--TANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ 460
Query: 532 -KLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
+L+ + DL SL+ +TK L E ++Q +E AA +E +KLKV
Sbjct: 461 ERLQNELDLTKDSLK----ETKDALLNVEGELEQERQQHEETIAAMKEEEKLKV 510
Score = 31.9 bits (69), Expect = 6.9
Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 9/92 (9%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + +ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 748 RITDLQEELRH----REHRISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 803
Query: 250 LKNQLEK-----QNFEFQQVTSKLKELEYERD 276
L+ EK E Q+ ++LK + ERD
Sbjct: 804 LEEMEEKYLMRESKPEDIQMITELKAMLTERD 835
>BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein.
Length = 1377
Score = 51.6 bits (118), Expect = 8e-06
Identities = 113/534 (21%), Positives = 209/534 (39%), Gaps = 35/534 (6%)
Query: 100 IAAKAQITKLESRVNHQHTIRKEMQI-LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
+ K + K E R ++E+Q +E EK R+E + ED
Sbjct: 773 LVEKHTLEKEELRKELLEKHQRELQEGRYESEKLQQENSILRNEITTLNEEDSISNLKLG 832
Query: 159 XXX-XKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDK----------LLEANVSNKD 207
++E + K A K +L KQI++LK K L + N N++
Sbjct: 833 TLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQE 892
Query: 208 QISEMKKDMDELL--QALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQV 264
++ E+ + + E+L + E S +E ++E E+C Q + E +V
Sbjct: 893 KLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEV 952
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLE 323
+ ++ E KD + + R ++++ +++++ L NE+ L++ K L
Sbjct: 953 KIQTHIVQQENHLLKD-ELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALS 1007
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESAL 383
E+++ ++ ++ + K + S E Q S S A E L D +++
Sbjct: 1008 EELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVN 1066
Query: 384 GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLL 443
L +EV +L + A GK S +H QKRL
Sbjct: 1067 LQMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLS 1124
Query: 444 LVTRER-DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIA 498
+ + QQL E E T+ + + +V+QLE +L Q + +
Sbjct: 1125 WDKLDHLMNEEQQLLWQENERLQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSG 1183
Query: 499 AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLT 557
+P K SL+ E ++++E A R V+++ + +++L T LE G + K + L
Sbjct: 1184 TMNPTEQEKL--SLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL- 1240
Query: 558 NNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
+ E Q S + L++ ++ E+ LQ RQ L+ RI
Sbjct: 1241 DEQLMEMQHLRSTATPSPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 1294
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 29/257 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1002 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1060
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1061 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1116
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E Q+ V+ K EL T E+ QL++ L
Sbjct: 1117 HNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAEL---THSREKVRQLESNLLP 1173
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1174 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1233
Query: 313 RDAICNKLLLEEQVHQL 329
+ ++ L+EQ+ ++
Sbjct: 1234 KK---KQVKLDEQLMEM 1247
Score = 34.3 bits (75), Expect = 1.3
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 18/201 (8%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 649 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 704
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 705 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 764
Query: 287 TAQKRLCNMAE---LEKEVTR---LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
Q++L ++ E LEKE R L ++R L++ L+++ L + + L
Sbjct: 765 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGRYESEKLQQENSILRNEITTLNE-- 822
Query: 341 LELHEAKVKLSSVE-SQLESW 360
E + +KL ++ SQ E W
Sbjct: 823 -EDSISNLKLGTLNGSQEEMW 842
Score = 32.3 bits (70), Expect = 5.3
Identities = 32/141 (22%), Positives = 71/141 (50%), Gaps = 16/141 (11%)
Query: 187 LHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTS 242
L ++ K+ + +A +++ K +I + + +D++++ E +S++ E LK + +
Sbjct: 346 LENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVD 405
Query: 243 RAEQCTQLKNQ--LEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ +N+ L K + E+++ + LK EL ER+ Q + ++RL ELE
Sbjct: 406 DHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELE 456
Query: 300 KEVTRLRANERSLRDAICNKL 320
+E+ + + E +RD + L
Sbjct: 457 QEIEKAKTEENYIRDRLALSL 477
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 51.6 bits (118), Expect = 8e-06
Identities = 88/377 (23%), Positives = 147/377 (38%), Gaps = 34/377 (9%)
Query: 16 PFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKR-- 73
P R T PK AST + + S+ G S + G+ SS S TP
Sbjct: 6 PTARKTTTRRPKPTRPASTGVAGASSSL----GPSGSASAGELSSSEPSTPAQTPLAAPI 61
Query: 74 LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS 133
+ + PP P +K + +AQ+ LE ++ R E ++ K
Sbjct: 62 IPTPVLTSPGAVPPLPSPSKEEE----GLRAQVRDLEEKLETLRLKRAE-----DKAKLK 112
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI-- 191
+E+HK V + + E AKE + K + +E D I
Sbjct: 113 ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEM 172
Query: 192 ADLKDKLLEANVSNKDQ-ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL 250
A L ++ E + Q + +K+ +DEL LE ++E+E K + A QL
Sbjct: 173 ATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE------KGSDGAASSYQL 226
Query: 251 KNQLEKQNFEFQQVTSKLKEL-EYERDSYKDWQTQSKTAQKRL----CNMAELEKEVTRL 305
K QLE+QN + ++++L E+ + Q + + L L++E+++
Sbjct: 227 K-QLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQA 285
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
+ L++ + L EE V LT R L+ EL E L ++ + AR
Sbjct: 286 ESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENAR 345
Query: 366 AHGVESAGALRDALESA 382
+E LR+ L+ A
Sbjct: 346 ETELE----LREQLDMA 358
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 51.6 bits (118), Expect = 8e-06
Identities = 72/349 (20%), Positives = 149/349 (42%), Gaps = 29/349 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
+EKA L E+++ + + ++D A+ E +D+K ++ +L+
Sbjct: 592 KEKAFLFEKYQEAQEEIMKLKDTLKSQMT---------QEASDEAEDMKEAMNRMIDELN 642
Query: 189 KQIADLKDKLLEANV---------SNKDQISEM--KKDMDELLQALEGAQSEVEMLKKEL 237
KQ+++L EA S +D +E K + ++L+Q ++++ E E+
Sbjct: 643 KQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEM 702
Query: 238 VKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM- 295
Q S+ + TQLK ++ Q +T L+ + R + K+ + + ++ L +
Sbjct: 703 KSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 762
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
E+ K +L + ++ DA+ + E+ L S V L E + K K+ S
Sbjct: 763 VEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVV 822
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
Q+ S +S + E+ L + E + +E + L+ ++D
Sbjct: 823 QIRSEVSQVKRE-KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKD 881
Query: 416 KATGKLNDLT-TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
K K+N+++ V K +E+L Q + +R S QQL+ ++++
Sbjct: 882 K---KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQS--QQLEALQQQV 925
Score = 46.4 bits (105), Expect = 3e-04
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI----------SEMKKDMD 217
TAAKE ++ +N + ++A L+ +LLE + D + S ++ ++
Sbjct: 742 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 801
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ----LEKQNFEFQQVTSKLKELEY 273
L L+ + E E + E+V+ S Q + K L+ + E ++ K ++ +
Sbjct: 802 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQE 861
Query: 274 ERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E K + ++ SK + + + E+ KEVT+L+ SL + + Q QL +
Sbjct: 862 ELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 921
Query: 333 VEALQPVQLELHEAKVKLSSVES 355
+ ++ +Q +L E K + V S
Sbjct: 922 QQQVKQLQNQLAECKKQHQEVIS 944
Score = 41.9 bits (94), Expect = 0.006
Identities = 86/456 (18%), Positives = 182/456 (39%), Gaps = 37/456 (8%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
+DL+ + + + + +L+ + E N +ISE D L Q L+ QS+ E
Sbjct: 439 QDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD---LSQKLKETQSKYEEA 495
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC 293
KE++ + + ++ + F ++ +E+ + ++ +S+ ++++
Sbjct: 496 MKEVLSVQKQMKLGLVSPESMDNYS-HFHELRVTEEEINVLKQDLQNALEESERNKEKVR 554
Query: 294 NMAE--LEKE---VTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
+ E +E+E V + E ++ + C+ ++E + E Q Q E+ + K
Sbjct: 555 ELEEKLVEREKGTVIKPPVEEYEEMKSSYCS--VIENMNKEKAFLFEKYQEAQEEIMKLK 612
Query: 348 VKLSSVESQLESWMSAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLTEE 406
+++SQ+ S E+ + D L + + E
Sbjct: 613 ---DTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLE 669
Query: 407 VATLKYERDKATGKLNDLTTV-RKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
T +Y KL LT V R E + ++ + V E +Q +D +KE +V
Sbjct: 670 DVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDA-QKENSV 728
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
++ E + L +++E+ + ++ H SK +E + E E+A
Sbjct: 729 SI--TEHLQVITTLRTAAKEMEEKISNLKE-------HLASKEVEVAKLEKQLLEEKA-- 777
Query: 526 ARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK-- 583
A D R+ + L +SLE + VL + + ++++ E+ + E+ ++K
Sbjct: 778 AMTDAMVPRSSYEKLQSSLE---SEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKRE 834
Query: 584 ---VALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
+ + + EL Q QQ + ++KRYS
Sbjct: 835 KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYS 870
Score = 32.7 bits (71), Expect = 4.0
Identities = 52/284 (18%), Positives = 113/284 (39%), Gaps = 19/284 (6%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEE-EKASLIEQHKRDERAVSDMEDXXXXXXXXX 159
A I +L +V+ + KE Q E+ K +E + ++ E
Sbjct: 633 AMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSR 692
Query: 160 XXXKDEFNTAAKEHKDL--KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+D + ++ + + K+ D K+ + + L+ + + EM++ +
Sbjct: 693 AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 752
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
L + L + EV L+K+L+++ + ++ EK + S L E
Sbjct: 753 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKE--- 809
Query: 278 YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ 337
K +K + ++ EV++++ + +++ + +K E++V++L ++ Q
Sbjct: 810 ------SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSK---EQEVNEL---LQKFQ 857
Query: 338 PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALES 381
Q EL E K + S S+LE + L++AL S
Sbjct: 858 QAQEELAEMK-RYSESSSKLEEDKDKKINEMSKEVTKLKEALNS 900
Score = 31.5 bits (68), Expect = 9.2
Identities = 36/182 (19%), Positives = 74/182 (40%), Gaps = 7/182 (3%)
Query: 91 ETKRLKIDLIAAKAQITKL----ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS 146
E +L+ L+ KA +T S Q ++ E+ +L + K S+ E+ K V
Sbjct: 764 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 823
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH--KQIADLKDKLLEANVS 204
+ + + +E +L + + + +L K+ ++ KL E
Sbjct: 824 -IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDK 882
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+++S+ + E L +L K++ + + +Q QL+NQL + + Q+V
Sbjct: 883 KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEV 942
Query: 265 TS 266
S
Sbjct: 943 IS 944
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/369 (22%), Positives = 158/369 (42%), Gaps = 37/369 (10%)
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR 304
E+C ++ K++ + +++ ++++L+ E YKD + K +K N +L KE
Sbjct: 358 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLK--EKEHKNQDDLLKEKET 415
Query: 305 LRANERSLRDAICNK-LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
L + L++ + K + L+ Q+ + AL + + K K+ +E+ LE+
Sbjct: 416 L---IQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILET-QKV 471
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
R+H SA +D LE HL + V K K +
Sbjct: 472 ERSH---SAKLEQDILEK----ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEE 524
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARV 483
+T + N + + H LQ L E ++ RQ+ + ++EL+ + + L A +
Sbjct: 525 ITQLTNNLQDMKHLLQ----LKEEEEETNRQETEKLKEELSASSARTQN------LKADL 574
Query: 484 QQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Q+ E + Y DL K ++ ++ EV+ R+E + R + +L +++ +
Sbjct: 575 QRKE---EDYADL--KEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQE 629
Query: 544 L---ERIGPQTKVLHLTNNPAAEAQKQIS---KELEAAQEEIKKLKVALREGGAQADPEE 597
L +R Q K L N EA +Q K+L ++ I+ +++ L E Q E+
Sbjct: 630 LDMKQRTIQQLKE-QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEE-QEQTQVEQ 687
Query: 598 LQQMRQQLE 606
Q + +LE
Sbjct: 688 DQVLEAKLE 696
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/273 (17%), Positives = 115/273 (42%), Gaps = 13/273 (4%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
++ K +++L V KE++ + E +K K E+ + + E
Sbjct: 438 VVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKL-EQDILEKESIILKLERN 496
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLL---EANVSNKDQISEM 212
++ + K KDL K K T L + D+K L E +N+ + ++
Sbjct: 497 LKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKL 556
Query: 213 KKDMDELLQALEGAQSEVEMLKKELV----KQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
K+++ + +++++ +++ K T +Q Q++ ++ E + + K+
Sbjct: 557 KEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 616
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
ELE +++ + ++L +K ++ ER+ +D + ++E+
Sbjct: 617 NELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMT 676
Query: 329 LTSRVEALQPVQLELHEAKV-KLSSVESQLESW 360
L + E Q Q ++ EAK+ ++ + ++LE W
Sbjct: 677 LEEQ-EQTQVEQDQVLEAKLEEVERLATELEKW 708
Score = 41.9 bits (94), Expect = 0.006
Identities = 33/164 (20%), Positives = 77/164 (46%), Gaps = 7/164 (4%)
Query: 113 VNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKE 172
+N + I ++M++ EE++ + +EQ + E + ++E K++ N +
Sbjct: 663 LNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVE----RLATELEKWKEKCNDLETK 718
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+ + TD+ ++ +L+D+L E S + ++ KK ++E + + A+ +
Sbjct: 719 NNQRSNKEHENNTDVLGKLTNLQDELQE---SEQKYNADRKKWLEEKMMLITQAKEAENI 775
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
KE+ K E+ + +N++E + + S L++ ERD
Sbjct: 776 RNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERD 819
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 51.6 bits (118), Expect = 8e-06
Identities = 81/369 (21%), Positives = 158/369 (42%), Gaps = 37/369 (10%)
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR 304
E+C ++ K++ + +++ ++++L+ E YKD + K + + N +L KE
Sbjct: 273 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEREHK--NQDDLLKEKET 330
Query: 305 LRANERSLRDAICNK-LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
L + L++ + K + L+ Q+ + AL + + K K+ +E+ LE+
Sbjct: 331 L---IQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILET-QKV 386
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
R+H SA +D LE HL + V K K +
Sbjct: 387 ERSH---SAKLEQDILEK----ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEE 439
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARV 483
+T + N + + H LQ L E ++ RQ+ + ++EL+ + + L A +
Sbjct: 440 ITQLTNNLQDMKHLLQ----LKEEEEETNRQETEKLKEELSASSARTQN------LKADL 489
Query: 484 QQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Q+ E + Y DL K ++ ++ EV+ R+E + R + +L +++ +
Sbjct: 490 QRKE---EDYADL--KEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQE 544
Query: 544 L---ERIGPQTKVLHLTNNPAAEAQKQIS---KELEAAQEEIKKLKVALREGGAQADPEE 597
L +R Q K L N EA +Q K+L ++ I+ +++ L E Q E+
Sbjct: 545 LDMKQRTIQQLKE-QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEE-QEQTQVEQ 602
Query: 598 LQQMRQQLE 606
Q + +LE
Sbjct: 603 DQVLEAKLE 611
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/273 (17%), Positives = 115/273 (42%), Gaps = 13/273 (4%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
++ K +++L V KE++ + E +K K E+ + + E
Sbjct: 353 VVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKL-EQDILEKESIILKLERN 411
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLL---EANVSNKDQISEM 212
++ + K KDL K K T L + D+K L E +N+ + ++
Sbjct: 412 LKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKL 471
Query: 213 KKDMDELLQALEGAQSEVEMLKKELV----KQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
K+++ + +++++ +++ K T +Q Q++ ++ E + + K+
Sbjct: 472 KEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 531
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
ELE +++ + ++L +K ++ ER+ +D + ++E+
Sbjct: 532 NELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMT 591
Query: 329 LTSRVEALQPVQLELHEAKV-KLSSVESQLESW 360
L + E Q Q ++ EAK+ ++ + ++LE W
Sbjct: 592 LEEQ-EQTQVEQDQVLEAKLEEVERLATELEKW 623
Score = 33.9 bits (74), Expect = 1.7
Identities = 44/241 (18%), Positives = 98/241 (40%), Gaps = 16/241 (6%)
Query: 72 KRLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
++L+ + S + + +R + D K ++T + ++ ++KE+ ++ +E+K
Sbjct: 469 EKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQ---VQKEVSVMRDEDK 525
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI 191
I+ ++ +++ + K++ N E + +++ DL+
Sbjct: 526 LLRIKINELEKKK-NQCSQELDMKQRTIQQLKEQLNNQKVE--EAIQQYERACKDLN--- 579
Query: 192 ADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLK 251
+K+K++E + + E ++ E Q LE EVE L EL K +
Sbjct: 580 --VKEKIIE---DMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKN 634
Query: 252 NQLEKQNFEFQ-QVTSKLKELEYE-RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
NQ + E V KL L+ E ++S + + K + + KE +R +
Sbjct: 635 NQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRKKK 694
Query: 310 R 310
+
Sbjct: 695 K 695
>AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein.
Length = 2090
Score = 51.6 bits (118), Expect = 8e-06
Identities = 108/515 (20%), Positives = 206/515 (40%), Gaps = 35/515 (6%)
Query: 119 IRKEMQIL-FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXX-XKDEFNTAAKEHKDL 176
+++++++L +E EK R+E + ED ++E + K
Sbjct: 1505 MQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETVKQE 1564
Query: 177 KANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQISEMKKDMDELL--QALE 224
A K +L KQI++LK K L + N N++++ E+ + + E+L + E
Sbjct: 1565 NAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKE 1624
Query: 225 GAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
S +E ++E E+C Q + E +V + ++ E KD +
Sbjct: 1625 PGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKD-EL 1683
Query: 284 QSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ R ++++ +++++ L NE+ L++ K L E+++ ++ ++
Sbjct: 1684 EKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSEELNSCVDKLAKSSLLEHR 1739
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
+ K + S E Q S S A E L D +++
Sbjct: 1740 IATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEA 1798
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER-DSYRQQLDCYEK 461
L +EV +L + A GK S +H QKRL + + QQL E
Sbjct: 1799 LKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLWQEN 1856
Query: 462 ELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAAHDPHAHSKALESLRNEVT 517
E T+ + + +V+QLE +L Q + + +P K SL+ E
Sbjct: 1857 ERLQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKL--SLKRECD 1913
Query: 518 RWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
++++E A R V+++ + +++L T LE G + K + L + E Q S +
Sbjct: 1914 QFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL-DEQLMEMQHLRSTATPSPS 1972
Query: 577 EEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
L++ ++ E+ LQ RQ L+ RI
Sbjct: 1973 PHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 2007
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 29/257 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1715 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1773
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1774 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1829
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E Q+ V+ K EL T E+ QL++ L
Sbjct: 1830 HNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAEL---THSREKVRQLESNLLP 1886
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1887 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1946
Query: 313 RDAICNKLLLEEQVHQL 329
+ ++ L+EQ+ ++
Sbjct: 1947 KK---KQVKLDEQLMEM 1960
Score = 38.3 bits (85), Expect = 0.080
Identities = 37/172 (21%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 649 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 704
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 705 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 764
Query: 287 TAQKRLCNMAE---LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
Q++L ++ E LEKE R E+ R+ + +E + ++ T+++EA
Sbjct: 765 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTTQIEA 816
Score = 35.9 bits (79), Expect = 0.43
Identities = 45/221 (20%), Positives = 90/221 (40%), Gaps = 19/221 (8%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQA 222
+ E ++ ++ K+ W+ EK +L ++ A+ ++ LL+ + + S + E+L+
Sbjct: 841 RQELKDLQEQQREEKSQWEFEKDELTQECAEAQE-LLKETLKREKTTSLVLTQEREMLE- 898
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
++ E L +V++ + L+N E Q +LK ++
Sbjct: 899 ----KTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSLLSDQILELKSSHIRELREREEV 954
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLT----SRVEALQP 338
A ++L + + + RL R + +KLL E +H+ T R A
Sbjct: 955 LCQAGASEQLAS-----QRLERLEMEHAQERQEMMSKLLAMENIHKATCETADRERAEMS 1009
Query: 339 VQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
++ ++K+K +S S L+S VE GAL
Sbjct: 1010 TEISRLQSKIKEMQQATSPLSMLQSGCQVIGEEEVEGDGAL 1050
Score = 33.1 bits (72), Expect = 3.0
Identities = 31/141 (21%), Positives = 71/141 (50%), Gaps = 16/141 (11%)
Query: 187 LHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTS 242
L ++ K+ + +A +++ K ++ + + +D++++ E +S++ E LK + +
Sbjct: 346 LENELLVTKNSIHQAALASFKAEVRHLLERVDQVVREKEKLRSDLDKAEKLKSSMASEVD 405
Query: 243 RAEQCTQLKNQ--LEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ +N+ L K + E+++ + LK EL ER+ Q + ++RL ELE
Sbjct: 406 DHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELE 456
Query: 300 KEVTRLRANERSLRDAICNKL 320
+E+ + + E +RD + L
Sbjct: 457 QEIEKAKTEENYIRDRLALSL 477
>AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein.
Length = 2096
Score = 51.6 bits (118), Expect = 8e-06
Identities = 108/515 (20%), Positives = 206/515 (40%), Gaps = 35/515 (6%)
Query: 119 IRKEMQIL-FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXX-XKDEFNTAAKEHKDL 176
+++++++L +E EK R+E + ED ++E + K
Sbjct: 1511 MQQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETVKQE 1570
Query: 177 KANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQISEMKKDMDELL--QALE 224
A K +L KQI++LK K L + N N++++ E+ + + E+L + E
Sbjct: 1571 NAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKE 1630
Query: 225 GAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
S +E ++E E+C Q + E +V + ++ E KD +
Sbjct: 1631 PGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKD-EL 1689
Query: 284 QSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLE 342
+ R ++++ +++++ L NE+ L++ K L E+++ ++ ++
Sbjct: 1690 EKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSEELNSCVDKLAKSSLLEHR 1745
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
+ K + S E Q S S A E L D +++
Sbjct: 1746 IATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEA 1804
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER-DSYRQQLDCYEK 461
L +EV +L + A GK S +H QKRL + + QQL E
Sbjct: 1805 LKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLWQEN 1862
Query: 462 ELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAAHDPHAHSKALESLRNEVT 517
E T+ + + +V+QLE +L Q + + +P K SL+ E
Sbjct: 1863 ERLQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKL--SLKRECD 1919
Query: 518 RWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQ 576
++++E A R V+++ + +++L T LE G + K + L + E Q S +
Sbjct: 1920 QFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL-DEQLMEMQHLRSTATPSPS 1978
Query: 577 EEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
L++ ++ E+ LQ RQ L+ RI
Sbjct: 1979 PHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 2013
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 29/257 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1721 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1779
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1780 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1835
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E Q+ V+ K EL T E+ QL++ L
Sbjct: 1836 HNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAEL---THSREKVRQLESNLLP 1892
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1893 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1952
Query: 313 RDAICNKLLLEEQVHQL 329
+ ++ L+EQ+ ++
Sbjct: 1953 KK---KQVKLDEQLMEM 1966
Score = 37.9 bits (84), Expect = 0.11
Identities = 38/172 (22%), Positives = 82/172 (47%), Gaps = 11/172 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 655 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 710
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 711 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 770
Query: 287 TAQKRLCNMAE---LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
Q++L ++ E LEKE R E+ R+ + +E + + TS++EA
Sbjct: 771 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNIRTSQIEA 822
Score = 32.3 bits (70), Expect = 5.3
Identities = 32/141 (22%), Positives = 71/141 (50%), Gaps = 16/141 (11%)
Query: 187 LHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTS 242
L ++ K+ + +A +++ K +I + + +D++++ E +S++ E LK + +
Sbjct: 352 LENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVD 411
Query: 243 RAEQCTQLKNQ--LEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ +N+ L K + E+++ + LK EL ER+ Q + ++RL ELE
Sbjct: 412 DHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELE 462
Query: 300 KEVTRLRANERSLRDAICNKL 320
+E+ + + E +RD + L
Sbjct: 463 QEIEKAKTEENYIRDRLALSL 483
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 51.6 bits (118), Expect = 8e-06
Identities = 88/377 (23%), Positives = 147/377 (38%), Gaps = 34/377 (9%)
Query: 16 PFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKR-- 73
P R T PK AST + + S+ G S + G+ SS S TP
Sbjct: 6 PTARKTTTRRPKPTRPASTGVAGASSSL----GPSGSASAGELSSSEPSTPAQTPLAAPI 61
Query: 74 LRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS 133
+ + PP P +K + +AQ+ LE ++ R E ++ K
Sbjct: 62 IPTPVLTSPGAVPPLPSPSKEEE----GLRAQVRDLEEKLETLRLKRAE-----DKAKLK 112
Query: 134 LIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI-- 191
+E+HK V + + E AKE + K + +E D I
Sbjct: 113 ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEM 172
Query: 192 ADLKDKLLEANVSNKDQ-ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL 250
A L ++ E + Q + +K+ +DEL LE ++E+E K + A QL
Sbjct: 173 ATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE------KGSDGAASSYQL 226
Query: 251 KNQLEKQNFEFQQVTSKLKEL-EYERDSYKDWQTQSKTAQKRL----CNMAELEKEVTRL 305
K QLE+QN + ++++L E+ + Q + + L L++E+++
Sbjct: 227 K-QLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQA 285
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAAR 365
+ L++ + L EE V LT R L+ EL E L ++ + AR
Sbjct: 286 ESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENAR 345
Query: 366 AHGVESAGALRDALESA 382
+E LR+ L+ A
Sbjct: 346 ETELE----LREQLDMA 358
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/436 (18%), Positives = 174/436 (39%), Gaps = 26/436 (5%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
K LE ++ + + + ++ L+ +E + E K+ + LK+QLE
Sbjct: 431 KELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLE 490
Query: 256 ---KQNFEFQQVTSKLKELEYERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERS 311
K+N Q T K+ +L+ + D +T+S TA + AE K++ +L +N R
Sbjct: 491 DLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRD 550
Query: 312 LRDAIC----NKLLLEEQVHQLTSRVEALQPVQLE----LHEAKVKLSSVESQLESWMSA 363
L+D C KL LE++ L S +E+ + + +++ + ++ +E L++
Sbjct: 551 LQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKIL 610
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
+E + L +E A K + + K
Sbjct: 611 LAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKI 670
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD--CYEKELTVTLCGEEGAGSVALLSA 481
++ + + + ++K+LL E + +Q+++ E E +L + S ++
Sbjct: 671 YESIEEAKSEAMKEMEKKLL----EERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINE 726
Query: 482 RVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLT 541
++Q + + R+L + + L +N++ ++ + +L+ + + L
Sbjct: 727 LLKQKDVLNEDVRNLTLKIEQETQKRCL--TQNDLKMQTQQVNTLKMSEKQLKQENNHLM 784
Query: 542 ASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADP-----E 596
+ Q L A K++ +LEA Q K +RE + + +
Sbjct: 785 EMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGK 844
Query: 597 ELQQMRQQLENSRIKL 612
ELQQ +Q+L++ R L
Sbjct: 845 ELQQKKQELQDERDSL 860
Score = 42.3 bits (95), Expect = 0.005
Identities = 74/377 (19%), Positives = 166/377 (44%), Gaps = 31/377 (8%)
Query: 102 AKAQITK-LESRVNHQHTIRKEMQ-ILFEEEK-ASLIE-QHKRDERAVSDM--EDXXXXX 155
AK++ K +E ++ + T++++++ +L E EK SL++ K+ ++ ++++ +
Sbjct: 677 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNE 736
Query: 156 XXXXXXXKDEFNTAAK--EHKDLKANWDKEKT--DLHKQIADLKDKLLEANVSNKDQISE 211
K E T + DLK + T KQ+ + L+E ++ + Q +E
Sbjct: 737 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 796
Query: 212 MKKDMDELLQALEGAQSEVE-MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
++K+ Q +G E++ L+ E T Q +LK + E++ +++ K +E
Sbjct: 797 LRKER----QDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 852
Query: 271 LEYERDSYKDWQ--TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL--EEQV 326
L+ ERDS T +K ++L + E++ + L E+ +++ +++ ++++
Sbjct: 853 LQDERDSLAAQLEITLTKADSEQLAR-SIAEEQYSDLE-KEKIMKELEIKEMMARHKQEL 910
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXX 386
+ + + +L+ L L++ + +L + + + E L+D SA
Sbjct: 911 TEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ----EQLSRLKDEEISAAAIK 966
Query: 387 XXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
++A + R + + ND RK +E+ +K + +
Sbjct: 967 AQFEKQLLTERTLKTQAVNKLAEI-MNRKEPVKRGNDTDVRRKEKEN-----RKLHMELK 1020
Query: 447 RERDSYRQQLDCYEKEL 463
ER+ QQ+ Y+KEL
Sbjct: 1021 SEREKLTQQMIKYQKEL 1037
Score = 40.3 bits (90), Expect = 0.020
Identities = 36/195 (18%), Positives = 81/195 (41%), Gaps = 7/195 (3%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E+ A D K N + + L Q+ DLK + + +S ++++++++ +DE L
Sbjct: 463 EYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST-EKVNQLQRQLDETNALLR 521
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
L+K + + + +Q L+ +N + KL++ S + + +
Sbjct: 522 TESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERR 581
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+T + N +L+ + L E L++ +E + QL R L+ + +
Sbjct: 582 DRTHGSEIIN--DLQGRICGL---EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNME 636
Query: 345 -EAKVKLSSVESQLE 358
+ +L ++ LE
Sbjct: 637 IDMTYQLKVIQQSLE 651
Score = 35.9 bits (79), Expect = 0.43
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 30/213 (14%)
Query: 182 KEKTDLHKQIADLKDKL--LEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+E + + +++ KL LE ++SN+ Q E EL Q + + +E KEL +
Sbjct: 382 RETDSIQSRKNEIQKKLYTLEEHLSNEMQAKE------ELEQKCKSVNTRLEKTAKELEE 435
Query: 240 QTSRAEQCTQLKNQLEKQ-------NFEFQQ----VTSKLKELEYE----RDSYKDWQTQ 284
+ + + QLE++ N E+Q+ K + LE + +D +D + +
Sbjct: 436 EITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKR 495
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRD--AICNKLLLE--EQVHQLTSRVEALQPVQ 340
++ +Q + +L++++ A R+ D A K E +Q+ QL S LQ
Sbjct: 496 NQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN 555
Query: 341 LELHEAKVKLSSVESQLESWMSAA---RAHGVE 370
L AK+KL L+S + + R HG E
Sbjct: 556 CLLETAKLKLEKEFINLQSALESERRDRTHGSE 588
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 51.6 bits (118), Expect = 8e-06
Identities = 72/349 (20%), Positives = 149/349 (42%), Gaps = 29/349 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
+EKA L E+++ + + ++D A+ E +D+K ++ +L+
Sbjct: 601 KEKAFLFEKYQEAQEEIMKLKDTLKSQMT---------QEASDEAEDMKEAMNRMIDELN 651
Query: 189 KQIADLKDKLLEANV---------SNKDQISEM--KKDMDELLQALEGAQSEVEMLKKEL 237
KQ+++L EA S +D +E K + ++L+Q ++++ E E+
Sbjct: 652 KQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEM 711
Query: 238 VKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM- 295
Q S+ + TQLK ++ Q +T L+ + R + K+ + + ++ L +
Sbjct: 712 KSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 771
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
E+ K +L + ++ DA+ + E+ L S V L E + K K+ S
Sbjct: 772 VEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVV 831
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
Q+ S +S + E+ L + E + +E + L+ ++D
Sbjct: 832 QIRSEVSQVKRE-KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKD 890
Query: 416 KATGKLNDLT-TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
K K+N+++ V K +E+L Q + +R S QQL+ ++++
Sbjct: 891 K---KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQS--QQLEALQQQV 934
Score = 46.4 bits (105), Expect = 3e-04
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI----------SEMKKDMD 217
TAAKE ++ +N + ++A L+ +LLE + D + S ++ ++
Sbjct: 751 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 810
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ----LEKQNFEFQQVTSKLKELEY 273
L L+ + E E + E+V+ S Q + K L+ + E ++ K ++ +
Sbjct: 811 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQE 870
Query: 274 ERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E K + ++ SK + + + E+ KEVT+L+ SL + + Q QL +
Sbjct: 871 ELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 930
Query: 333 VEALQPVQLELHEAKVKLSSVES 355
+ ++ +Q +L E K + V S
Sbjct: 931 QQQVKQLQNQLAECKKQHQEVIS 953
Score = 41.9 bits (94), Expect = 0.006
Identities = 86/456 (18%), Positives = 182/456 (39%), Gaps = 37/456 (8%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
+DL+ + + + + +L+ + E N +ISE D L Q L+ QS+ E
Sbjct: 448 QDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD---LSQKLKETQSKYEEA 504
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC 293
KE++ + + ++ + F ++ +E+ + ++ +S+ ++++
Sbjct: 505 MKEVLSVQKQMKLGLVSPESMDNYS-HFHELRVTEEEINVLKQDLQNALEESERNKEKVR 563
Query: 294 NMAE--LEKE---VTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
+ E +E+E V + E ++ + C+ ++E + E Q Q E+ + K
Sbjct: 564 ELEEKLVEREKGTVIKPPVEEYEEMKSSYCS--VIENMNKEKAFLFEKYQEAQEEIMKLK 621
Query: 348 VKLSSVESQLESWMSAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLTEE 406
+++SQ+ S E+ + D L + + E
Sbjct: 622 ---DTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLE 678
Query: 407 VATLKYERDKATGKLNDLTTV-RKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
T +Y KL LT V R E + ++ + V E +Q +D +KE +V
Sbjct: 679 DVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDA-QKENSV 737
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
++ E + L +++E+ + ++ H SK +E + E E+A
Sbjct: 738 SI--TEHLQVITTLRTAAKEMEEKISNLKE-------HLASKEVEVAKLEKQLLEEKA-- 786
Query: 526 ARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK-- 583
A D R+ + L +SLE + VL + + ++++ E+ + E+ ++K
Sbjct: 787 AMTDAMVPRSSYEKLQSSLE---SEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKRE 843
Query: 584 ---VALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
+ + + EL Q QQ + ++KRYS
Sbjct: 844 KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYS 879
Score = 32.7 bits (71), Expect = 4.0
Identities = 52/284 (18%), Positives = 113/284 (39%), Gaps = 19/284 (6%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEE-EKASLIEQHKRDERAVSDMEDXXXXXXXXX 159
A I +L +V+ + KE Q E+ K +E + ++ E
Sbjct: 642 AMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSR 701
Query: 160 XXXKDEFNTAAKEHKDL--KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+D + ++ + + K+ D K+ + + L+ + + EM++ +
Sbjct: 702 AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 761
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
L + L + EV L+K+L+++ + ++ EK + S L E
Sbjct: 762 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKE--- 818
Query: 278 YKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQ 337
K +K + ++ EV++++ + +++ + +K E++V++L ++ Q
Sbjct: 819 ------SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSK---EQEVNEL---LQKFQ 866
Query: 338 PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALES 381
Q EL E K + S S+LE + L++AL S
Sbjct: 867 QAQEELAEMK-RYSESSSKLEEDKDKKINEMSKEVTKLKEALNS 909
Score = 31.5 bits (68), Expect = 9.2
Identities = 36/182 (19%), Positives = 74/182 (40%), Gaps = 7/182 (3%)
Query: 91 ETKRLKIDLIAAKAQITKL----ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS 146
E +L+ L+ KA +T S Q ++ E+ +L + K S+ E+ K V
Sbjct: 773 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 832
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH--KQIADLKDKLLEANVS 204
+ + + +E +L + + + +L K+ ++ KL E
Sbjct: 833 -IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDK 891
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+++S+ + E L +L K++ + + +Q QL+NQL + + Q+V
Sbjct: 892 KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEV 951
Query: 265 TS 266
S
Sbjct: 952 IS 953
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/369 (22%), Positives = 158/369 (42%), Gaps = 37/369 (10%)
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR 304
E+C ++ K++ + +++ ++++L+ E YKD + K +K N +L KE
Sbjct: 1062 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLK--EKEHKNQDDLLKEKET 1119
Query: 305 LRANERSLRDAICNK-LLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
L + L++ + K + L+ Q+ + AL + + K K+ +E+ LE+
Sbjct: 1120 L---IQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILET-QKV 1175
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
R+H SA +D LE HL + V K K +
Sbjct: 1176 ERSH---SAKLEQDILEK----ESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEE 1228
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARV 483
+T + N + + H LQ L E ++ RQ+ + ++EL+ + + L A +
Sbjct: 1229 ITQLTNNLQDMKHLLQ----LKEEEEETNRQETEKLKEELSASSARTQN------LKADL 1278
Query: 484 QQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS 543
Q+ E + Y DL K ++ ++ EV+ R+E + R + +L +++ +
Sbjct: 1279 QRKE---EDYADL--KEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQE 1333
Query: 544 L---ERIGPQTKVLHLTNNPAAEAQKQIS---KELEAAQEEIKKLKVALREGGAQADPEE 597
L +R Q K L N EA +Q K+L ++ I+ +++ L E Q E+
Sbjct: 1334 LDMKQRTIQQLKE-QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEE-QEQTQVEQ 1391
Query: 598 LQQMRQQLE 606
Q + +LE
Sbjct: 1392 DQVLEAKLE 1400
Score = 45.6 bits (103), Expect = 5e-04
Identities = 49/273 (17%), Positives = 115/273 (42%), Gaps = 13/273 (4%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
++ K +++L V KE++ + E +K K E+ + + E
Sbjct: 1142 VVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKL-EQDILEKESIILKLERN 1200
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLL---EANVSNKDQISEM 212
++ + K KDL K K T L + D+K L E +N+ + ++
Sbjct: 1201 LKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKL 1260
Query: 213 KKDMDELLQALEGAQSEVEMLKKELV----KQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
K+++ + +++++ +++ K T +Q Q++ ++ E + + K+
Sbjct: 1261 KEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 1320
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
ELE +++ + ++L +K ++ ER+ +D + ++E+
Sbjct: 1321 NELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMT 1380
Query: 329 LTSRVEALQPVQLELHEAKV-KLSSVESQLESW 360
L + E Q Q ++ EAK+ ++ + ++LE W
Sbjct: 1381 LEEQ-EQTQVEQDQVLEAKLEEVERLATELEKW 1412
Score = 41.9 bits (94), Expect = 0.006
Identities = 33/164 (20%), Positives = 77/164 (46%), Gaps = 7/164 (4%)
Query: 113 VNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKE 172
+N + I ++M++ EE++ + +EQ + E + ++E K++ N +
Sbjct: 1367 LNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVE----RLATELEKWKEKCNDLETK 1422
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+ + TD+ ++ +L+D+L E S + ++ KK ++E + + A+ +
Sbjct: 1423 NNQRSNKEHENNTDVLGKLTNLQDELQE---SEQKYNADRKKWLEEKMMLITQAKEAENI 1479
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERD 276
KE+ K E+ + +N++E + + S L++ ERD
Sbjct: 1480 RNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERD 1523
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 51.6 bits (118), Expect = 8e-06
Identities = 82/436 (18%), Positives = 174/436 (39%), Gaps = 26/436 (5%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEM-LKKELVKQTSRAEQCTQLKNQLE 255
K LE ++ + + + ++ L+ +E + E K+ + LK+QLE
Sbjct: 522 KELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLE 581
Query: 256 ---KQNFEFQQVTSKLKELEYERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERS 311
K+N Q T K+ +L+ + D +T+S TA + AE K++ +L +N R
Sbjct: 582 DLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRD 641
Query: 312 LRDAIC----NKLLLEEQVHQLTSRVEALQPVQLE----LHEAKVKLSSVESQLESWMSA 363
L+D C KL LE++ L S +E+ + + +++ + ++ +E L++
Sbjct: 642 LQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLKNGKIL 701
Query: 364 ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLND 423
+E + L +E A K + + K
Sbjct: 702 LAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKI 761
Query: 424 LTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD--CYEKELTVTLCGEEGAGSVALLSA 481
++ + + + ++K+LL E + +Q+++ E E +L + S ++
Sbjct: 762 YESIEEAKSEAMKEMEKKLL----EERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINE 817
Query: 482 RVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLT 541
++Q + + R+L + + L +N++ ++ + +L+ + + L
Sbjct: 818 LLKQKDVLNEDVRNLTLKIEQETQKRCL--TQNDLKMQTQQVNTLKMSEKQLKQENNHLM 875
Query: 542 ASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADP-----E 596
+ Q L A K++ +LEA Q K +RE + + +
Sbjct: 876 EMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGK 935
Query: 597 ELQQMRQQLENSRIKL 612
ELQQ +Q+L++ R L
Sbjct: 936 ELQQKKQELQDERDSL 951
Score = 42.3 bits (95), Expect = 0.005
Identities = 74/377 (19%), Positives = 166/377 (44%), Gaps = 31/377 (8%)
Query: 102 AKAQITK-LESRVNHQHTIRKEMQ-ILFEEEK-ASLIE-QHKRDERAVSDM--EDXXXXX 155
AK++ K +E ++ + T++++++ +L E EK SL++ K+ ++ ++++ +
Sbjct: 768 AKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNE 827
Query: 156 XXXXXXXKDEFNTAAK--EHKDLKANWDKEKT--DLHKQIADLKDKLLEANVSNKDQISE 211
K E T + DLK + T KQ+ + L+E ++ + Q +E
Sbjct: 828 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 887
Query: 212 MKKDMDELLQALEGAQSEVE-MLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE 270
++K+ Q +G E++ L+ E T Q +LK + E++ +++ K +E
Sbjct: 888 LRKER----QDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQE 943
Query: 271 LEYERDSYKDWQ--TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLL--EEQV 326
L+ ERDS T +K ++L + E++ + L E+ +++ +++ ++++
Sbjct: 944 LQDERDSLAAQLEITLTKADSEQLAR-SIAEEQYSDLE-KEKIMKELEIKEMMARHKQEL 1001
Query: 327 HQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXX 386
+ + + +L+ L L++ + +L + + + E L+D SA
Sbjct: 1002 TEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ----EQLSRLKDEEISAAAIK 1057
Query: 387 XXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVT 446
++A + R + + ND RK +E+ +K + +
Sbjct: 1058 AQFEKQLLTERTLKTQAVNKLAEI-MNRKEPVKRGNDTDVRRKEKEN-----RKLHMELK 1111
Query: 447 RERDSYRQQLDCYEKEL 463
ER+ QQ+ Y+KEL
Sbjct: 1112 SEREKLTQQMIKYQKEL 1128
Score = 40.3 bits (90), Expect = 0.020
Identities = 36/195 (18%), Positives = 81/195 (41%), Gaps = 7/195 (3%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E+ A D K N + + L Q+ DLK + + +S ++++++++ +DE L
Sbjct: 554 EYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST-EKVNQLQRQLDETNALLR 612
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
L+K + + + +Q L+ +N + KL++ S + + +
Sbjct: 613 TESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERR 672
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
+T + N +L+ + L E L++ +E + QL R L+ + +
Sbjct: 673 DRTHGSEIIN--DLQGRICGL---EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNME 727
Query: 345 -EAKVKLSSVESQLE 358
+ +L ++ LE
Sbjct: 728 IDMTYQLKVIQQSLE 742
Score = 36.7 bits (81), Expect = 0.24
Identities = 52/224 (23%), Positives = 100/224 (44%), Gaps = 33/224 (14%)
Query: 169 AAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQS 228
+ +E+ +++ ++E ++ K++ L++ L SN+ Q E EL Q + +
Sbjct: 467 SCRENDSIQSRKNEESQEIQKKLYTLEEHL-----SNEMQAKE------ELEQKCKSVNT 515
Query: 229 EVEMLKKELVKQTSRAEQCTQLKNQLEKQ-------NFEFQQ----VTSKLKELEYE--- 274
+E KEL ++ + + QLE++ N E+Q+ K + LE +
Sbjct: 516 RLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNS 575
Query: 275 -RDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD--AICNKLLLE--EQVHQL 329
+D +D + +++ +Q + +L++++ A R+ D A K E +Q+ QL
Sbjct: 576 LKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQL 635
Query: 330 TSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA---RAHGVE 370
S LQ L AK+KL L+S + + R HG E
Sbjct: 636 ESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSE 679
Score = 31.5 bits (68), Expect = 9.2
Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
LL + S ++ S + +E + + + E L E+ + ++C + +LEK
Sbjct: 461 LLSDSPSCRENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKT 520
Query: 258 NFEFQQ-------VTSKLKELEYERD--SYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN 308
E ++ V S L++LE E+ +K+ + Q K A LE +V L+
Sbjct: 521 AKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRK-ADHEADKKRNLENDVNSLKDQ 579
Query: 309 ERSLRDAICNKLLLEEQVHQLTSRVE 334
L+ N + E+V+QL +++
Sbjct: 580 LEDLKKRNQNSQISTEKVNQLQRQLD 605
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa
protein.
Length = 976
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/455 (18%), Positives = 183/455 (40%), Gaps = 37/455 (8%)
Query: 173 HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQAL---EGAQSE 229
H +L+ + + ++H ++ + +K+ K +I++ +K + LL + E +
Sbjct: 225 HGELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKD 284
Query: 230 VEMLKKELVKQTSRAEQCTQL-----KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+ L +E + ++ E+ T+L K +EKQ+ +++ L+ + K +
Sbjct: 285 LTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEED 344
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LE 342
+ A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE
Sbjct: 345 LQIATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 343 LHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXH 402
+E ++K+ ++E Q +S + + L+ LG
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET-------------- 445
Query: 403 LTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
L E + ++ G +L + + +E +H L+ +L +T Y +++ K+
Sbjct: 446 LLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KD 501
Query: 463 LTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREE 522
L L E+ + LE + + + + + + R ++
Sbjct: 502 LKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQ 561
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEE 578
E + T+LR + + + L++ + K L + +KQ+ +K +E Q+E
Sbjct: 562 IENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQE 621
Query: 579 IKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
K LK Q + E++ + +LE K K
Sbjct: 622 NKALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 51.2 bits (117), Expect = 1e-05
Identities = 97/449 (21%), Positives = 188/449 (41%), Gaps = 30/449 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKL-----LEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+N DKE L+++I LK+K+ LE + + + + ++D + L+ LE V
Sbjct: 481 SNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ 540
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL 292
K+EL KQ A + +LK+Q ++ QQ L+E + + + Q + ++L
Sbjct: 541 EKEELHKQLVEASE--RLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQL 598
Query: 293 CNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E+E ++ A + +R A + LE Q+ + EA + +L H
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVA--EASKERKLREHSENF-CK 655
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALG--XXXXXXXXXXXXXXXXXHLTEEVAT 409
+ES+LE+ G + + + H+ E
Sbjct: 656 QMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNV 715
Query: 410 LKYERDKATGKL---NDLTTVR-KNQESLIHRLQKRLLLVTRERDSY-RQQLDCYEKELT 464
K D + +L ++ ++ K ++S R + V +D Y R++ +++
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
+T E+ V L+A+ +QLE LQ DL A + AH +A + E+ +W + +
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQ---DLAAKKESVAHWEAQIA---EIIQWVSDEK 829
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
AR + L ++ +T LE + + + T +P + ++ ++ A E L+
Sbjct: 830 DARGYLQALASK---MTEELEAL-RSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 585 ALREGGAQADPEELQQMRQQLENSRIKLK 613
+R Q EEL++++ KLK
Sbjct: 886 EIR--AKQLVQEELRKVKDANLTLESKLK 912
Score = 41.9 bits (94), Expect = 0.006
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
++++N KD+ ++++D++ LQ +E + + L++E ++ + + ++ TQ L
Sbjct: 418 IMQSNTLTKDE--DVQRDLEHSLQ-MEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGS 474
Query: 258 NFEFQQVT--SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE----VTRLRANERS 311
+ ++K+L E + K+ S +++L + L +E RLR E+
Sbjct: 475 SRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQ 534
Query: 312 LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE-SQLESWMSAARAHGVE 370
R K L +Q+ + + R+++ + H+ + KL+ E S+L M+ RA +
Sbjct: 535 HRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQR-KLALQEFSELNERMAELRAQKQK 593
Query: 371 SAGALRDALE 380
+ LRD E
Sbjct: 594 VSRQLRDKEE 603
Score = 41.5 bits (93), Expect = 0.009
Identities = 56/277 (20%), Positives = 118/277 (42%), Gaps = 27/277 (9%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
++ A ++ + + +RKE++ ++ A ++ K E + + +
Sbjct: 604 EMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEA 663
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
A EH+ K K++L K++ +++L+ S+ ++ +KK++
Sbjct: 664 LKVKQGGRGAGATLEHQQ---EISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVH 720
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ Q E+ MLK +L K++ E+ N E ++ +K+ +YER+
Sbjct: 721 DSESHQLALQKEILMLKDKLE------------KSKRERHN-EMEEAVGTIKD-KYERER 766
Query: 278 YKDWQTQSK-TAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-HQLTSRVE 334
+ K TA+ ++LC+ V +L A R L D + + +E V H E
Sbjct: 767 AMLFDENKKLTAENEKLCSF------VDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAE 820
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+Q V E +A+ L ++ S++ + A R+ + S
Sbjct: 821 IIQWVSDE-KDARGYLQALASKMTEELEALRSSSLGS 856
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 42.3 bits (95), Expect = 0.005
Identities = 88/453 (19%), Positives = 183/453 (40%), Gaps = 36/453 (7%)
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N+ + H LK +++K + + ++ DK + ++ QI+E + M +L LE +
Sbjct: 234 NSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL-LIQITEKENKMKDLTFLLEES 292
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +V L+++ Q+ LK +EKQ+ +++ L+ + K + +
Sbjct: 293 RDKVNQLEEKTKLQSEN------LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LELH 344
A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE +
Sbjct: 347 IATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKN 401
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E ++K+ ++E Q +S + + L+ LG L
Sbjct: 402 EDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET--------------LL 447
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E + ++ G +L + + +E +H L+ +L +T Y +++ K+L
Sbjct: 448 YENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KDLK 503
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + LE + + + + + + R ++ E
Sbjct: 504 TELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE 563
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEEIK 580
+ T+LR + + + L++ + K L + +KQ+ +K +E Q+E K
Sbjct: 564 NLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENK 623
Query: 581 KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
LK Q + E++ + +LE K K
Sbjct: 624 ALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein.
Length = 634
Score = 51.2 bits (117), Expect = 1e-05
Identities = 74/376 (19%), Positives = 150/376 (39%), Gaps = 15/376 (3%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIR----KEMQIL---FEEEKASLIEQHKRDERAV 145
K L+ ++ KA+ E++V + I+ EMQ E EK S + +R E+ +
Sbjct: 217 KGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKEL 276
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSN 205
+ + E NT + + K+LK + E TD+ + A K +L
Sbjct: 277 QSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKI 336
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-EQCTQLKNQLEKQNFEFQQV 264
+ ++ ++ D + L A+E + + +EL+++ A E+ Q L+ + E +
Sbjct: 337 QSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENR 396
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE--LEKEVTRLRANERSLRDAICNKLLL 322
+ L++++ E D ++ + + R MAE KE+ +R + I N
Sbjct: 397 LADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKE 456
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESA 382
+ + L ++ +LQ L +++ L + L+ + + + R E A
Sbjct: 457 KNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMVERLK----QECRNFRSQAEKA 512
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYER-DKATGKLNDLTTVRKNQESLIHRLQKR 441
H E T + E+ ++A KL +K ++SL KR
Sbjct: 513 QLEAEKTLEEKQIQWLEEKHKLHECITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKR 572
Query: 442 LLLVTRERDSYRQQLD 457
L ++ +++L+
Sbjct: 573 LQEKVEVLEAKKEELE 588
Score = 47.6 bits (108), Expect = 1e-04
Identities = 100/536 (18%), Positives = 228/536 (42%), Gaps = 64/536 (11%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHK-RDERAVSDMED------XXXXXXXXXX 160
+L+ N + T ++++Q+L EE + L+E+ K +E + +
Sbjct: 61 ELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELET 120
Query: 161 XXKDEFNTAAKEHKDLKANWDK---EKTDLHKQIADLKDK----LLEANVSNKDQISEMK 213
++ F +E + +A ++K E T L + K++ L E + + +I+ ++
Sbjct: 121 PMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLE 180
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLK----NQLEKQNFEFQQVTSKLK 269
+D +EL ++L +L K + R EQ + K +L+ E ++ ++ +
Sbjct: 181 EDKEELRN---------QLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKE 231
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN--ERSLRDA------ICNKL- 320
E + ++ + Q + + E EK+ LRA E+ L+ + + NKL
Sbjct: 232 NSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLH 291
Query: 321 LLEEQVHQLTSRVEALQ-PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDAL 379
E +++ L+S+V+ L+ +LE+ + K++ + +S+LE + ++ ++ + + L
Sbjct: 292 KAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSE-LDGLQSDNEIL 350
Query: 380 ESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQ 439
++A+ E + ++ +++ KL L + E+ + L+
Sbjct: 351 KAAVEHHKVLLVEKD---------RELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLE 401
Query: 440 KRLLLVTRERDSYRQ-QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIA 498
K + E D +RQ + D YE++L + EE + +Q + LQ + ++
Sbjct: 402 KMKV----EHDVWRQSEKDQYEEKLRASQMAEE------ITRKELQSVRLKLQ--QQIVT 449
Query: 499 AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTN 558
+ L+ +++ + + + L +L +ER+ + +
Sbjct: 450 IENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMVERLKQECRNF---R 506
Query: 559 NPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
+ A +AQ + K LE Q + + K L E + E+ Q +++L+ + I K+
Sbjct: 507 SQAEKAQLEAEKTLEEKQIQWLEEKHKLHECITDRE-EKYNQAKEKLQRAAIAQKK 561
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 51.2 bits (117), Expect = 1e-05
Identities = 97/449 (21%), Positives = 188/449 (41%), Gaps = 30/449 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKL-----LEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+N DKE L+++I LK+K+ LE + + + + ++D + L+ LE V
Sbjct: 481 SNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ 540
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL 292
K+EL KQ A + +LK+Q ++ QQ L+E + + + Q + ++L
Sbjct: 541 EKEELHKQLVEASE--RLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQL 598
Query: 293 CNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E+E ++ A + +R A + LE Q+ + EA + +L H
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVA--EASKERKLREHSENF-CK 655
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALG--XXXXXXXXXXXXXXXXXHLTEEVAT 409
+ES+LE+ G + + + H+ E
Sbjct: 656 QMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNV 715
Query: 410 LKYERDKATGKL---NDLTTVR-KNQESLIHRLQKRLLLVTRERDSY-RQQLDCYEKELT 464
K D + +L ++ ++ K ++S R + V +D Y R++ +++
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
+T E+ V L+A+ +QLE LQ DL A + AH +A + E+ +W + +
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQ---DLAAKKESVAHWEAQIA---EIIQWVSDEK 829
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
AR + L ++ +T LE + + + T +P + ++ ++ A E L+
Sbjct: 830 DARGYLQALASK---MTEELEAL-RSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 585 ALREGGAQADPEELQQMRQQLENSRIKLK 613
+R Q EEL++++ KLK
Sbjct: 886 EIR--AKQLVQEELRKVKDANLTLESKLK 912
Score = 41.9 bits (94), Expect = 0.006
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
++++N KD+ ++++D++ LQ +E + + L++E ++ + + ++ TQ L
Sbjct: 418 IMQSNTLTKDE--DVQRDLEHSLQ-MEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGS 474
Query: 258 NFEFQQVT--SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE----VTRLRANERS 311
+ ++K+L E + K+ S +++L + L +E RLR E+
Sbjct: 475 SRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQ 534
Query: 312 LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE-SQLESWMSAARAHGVE 370
R K L +Q+ + + R+++ + H+ + KL+ E S+L M+ RA +
Sbjct: 535 HRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQR-KLALQEFSELNERMAELRAQKQK 593
Query: 371 SAGALRDALE 380
+ LRD E
Sbjct: 594 VSRQLRDKEE 603
Score = 41.5 bits (93), Expect = 0.009
Identities = 56/277 (20%), Positives = 118/277 (42%), Gaps = 27/277 (9%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
++ A ++ + + +RKE++ ++ A ++ K E + + +
Sbjct: 604 EMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEA 663
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
A EH+ K K++L K++ +++L+ S+ ++ +KK++
Sbjct: 664 LKVKQGGRGAGATLEHQQ---EISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVH 720
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ Q E+ MLK +L K++ E+ N E ++ +K+ +YER+
Sbjct: 721 DSESHQLALQKEILMLKDKLE------------KSKRERHN-EMEEAVGTIKD-KYERER 766
Query: 278 YKDWQTQSK-TAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-HQLTSRVE 334
+ K TA+ ++LC+ V +L A R L D + + +E V H E
Sbjct: 767 AMLFDENKKLTAENEKLCSF------VDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAE 820
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+Q V E +A+ L ++ S++ + A R+ + S
Sbjct: 821 IIQWVSDE-KDARGYLQALASKMTEELEALRSSSLGS 856
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 51.2 bits (117), Expect = 1e-05
Identities = 72/349 (20%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
+EKA L E++ + + +++D A+ E +D+K ++ +L+
Sbjct: 584 KEKAFLFEKYPEAQEGIMELKDTLKSQMT---------QEASDEAEDMKEAMNRMIDELN 634
Query: 189 KQIADLKDKLLEANV---------SNKDQISEM--KKDMDELLQALEGAQSEVEMLKKEL 237
KQ+++L EA S +D +E K + ++L+Q ++++ E E+
Sbjct: 635 KQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEM 694
Query: 238 VKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM- 295
Q S+ + TQLK ++ Q +T L+ + R + K+ + + ++ L +
Sbjct: 695 KSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 754
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
E+ K +L + ++ DA+ + E+ L S V L E + K K+ S
Sbjct: 755 VEVLKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVV 814
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
Q+ S +S + E+ L + E + E + L+ ++D
Sbjct: 815 QIRSEVSQVKRE-KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKD 873
Query: 416 KATGKLNDLT-TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
K K+N+++ V K +E+L Q + +R S QQL+ ++++
Sbjct: 874 K---KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQS--QQLEALQQQV 917
Score = 45.2 bits (102), Expect = 7e-04
Identities = 66/343 (19%), Positives = 144/343 (41%), Gaps = 24/343 (6%)
Query: 27 KDKLSASTNLNFSDSTQSIKEGLSNLLT-FGKRKSSIGSV----DDVTPDKRLRRDSSGN 81
KD L + SD + +KE ++ ++ K+ S + + D R R+
Sbjct: 604 KDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDV 663
Query: 82 GTTAPPSPWETKRLKIDLIA-AKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKR 140
K +++ ++ AKA+ E + + + + Q+ L++ K
Sbjct: 664 TAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL------KQLVDAQKE 717
Query: 141 DERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE 200
+ ++++ +++ + KEH A+ + E L KQ+ + K + +
Sbjct: 718 NSVSITEHLQVITTLRTAAKEMEEKISNL-KEHL---ASKEVEVLKLEKQLLEEKAAMTD 773
Query: 201 ANV--SNKDQI-SEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ---- 253
A V S+ +++ S ++ ++ L L+ + E E + E+V+ S Q + K
Sbjct: 774 AMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTL 833
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
L+ + E ++ K ++ + E K + ++ SK + + + E+ KEVT+L+ SL
Sbjct: 834 LKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL 893
Query: 313 RDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
+ + Q QL + + ++ +Q +L E K + V S
Sbjct: 894 SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVIS 936
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 51.2 bits (117), Expect = 1e-05
Identities = 72/349 (20%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
+EKA L E+++ + + ++D A+ E +D+K ++ +L+
Sbjct: 595 KEKAFLFEKYQEAQEEIMKLKDTLKSQMT---------QEASDEAEDMKEAMNRMIDELN 645
Query: 189 KQIADLKDKLLEANV---------SNKDQISEM--KKDMDELLQALEGAQSEVEMLKKEL 237
KQ+++L EA S +D +E K + ++L+Q ++++ E E+
Sbjct: 646 KQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEM 705
Query: 238 VKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM- 295
Q S+ + TQLK ++ Q +T L+ + R + K+ + + ++ L +
Sbjct: 706 KSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 765
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
E+ K +L + ++ DA+ + E+ L S V L E + K K+ S
Sbjct: 766 VEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVV 825
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
Q+ S +S + E+ L + E + E + L+ ++D
Sbjct: 826 QIRSEVSQVKRE-KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKD 884
Query: 416 KATGKLNDLT-TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
K K+N+++ V K +E+L Q + +R S QQL+ ++++
Sbjct: 885 K---KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQS--QQLEALQQQV 928
Score = 46.4 bits (105), Expect = 3e-04
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI----------SEMKKDMD 217
TAAKE ++ +N + ++A L+ +LLE + D + S ++ ++
Sbjct: 745 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 804
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ----LEKQNFEFQQVTSKLKELEY 273
L L+ + E E + E+V+ S Q + K L+ + E ++ K ++ +
Sbjct: 805 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQE 864
Query: 274 ERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E K + ++ SK + + + E+ KEVT+L+ SL + + Q QL +
Sbjct: 865 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 924
Query: 333 VEALQPVQLELHEAKVKLSSVES 355
+ ++ +Q +L E K + V S
Sbjct: 925 QQQVKQLQNQLAECKKQHQEVIS 947
Score = 40.7 bits (91), Expect = 0.015
Identities = 85/456 (18%), Positives = 182/456 (39%), Gaps = 37/456 (8%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
+DL+ + + + + +L+ + E N +ISE D L Q L+ QS+ E
Sbjct: 442 QDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD---LSQKLKETQSKYEEA 498
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC 293
KE++ + + ++ + F ++ +E+ + ++ +S+ ++++
Sbjct: 499 MKEVLSVQKQMKLGLVSPESMDNYS-HFHELRVTEEEINVLKQDLQNALEESERNKEKVR 557
Query: 294 NMAE--LEKE---VTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
+ E +E+E V + E ++ + C+ ++E + E Q Q E+ + K
Sbjct: 558 ELEEKLVEREKGTVIKPPVEEYEEMKSSYCS--VIENMNKEKAFLFEKYQEAQEEIMKLK 615
Query: 348 VKLSSVESQLESWMSAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLTEE 406
+++SQ+ S E+ + D L + + E
Sbjct: 616 ---DTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLE 672
Query: 407 VATLKYERDKATGKLNDLTTV-RKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
T +Y KL LT V R E + ++ + V E +Q +D +KE +V
Sbjct: 673 DVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDA-QKENSV 731
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
++ E + L +++E+ + ++ H SK +E + E E+A
Sbjct: 732 SI--TEHLQVITTLRTAAKEMEEKISNLKE-------HLASKEVEVAKLEKQLLEEKA-- 780
Query: 526 ARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK-- 583
A D R+ + L +SLE + VL + + ++++ E+ + E+ ++K
Sbjct: 781 AMTDAMVPRSSYEKLQSSLE---SEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKRE 837
Query: 584 ---VALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
+ + + EL Q QQ + ++KRY+
Sbjct: 838 KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYA 873
Score = 32.7 bits (71), Expect = 4.0
Identities = 37/182 (20%), Positives = 74/182 (40%), Gaps = 7/182 (3%)
Query: 91 ETKRLKIDLIAAKAQITKL----ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS 146
E +L+ L+ KA +T S Q ++ E+ +L + K S+ E+ K V
Sbjct: 767 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 826
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH--KQIADLKDKLLEANVS 204
+ + + +E +L + + + +L K+ A+ KL E
Sbjct: 827 -IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDK 885
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+++S+ + E L +L K++ + + +Q QL+NQL + + Q+V
Sbjct: 886 KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEV 945
Query: 265 TS 266
S
Sbjct: 946 IS 947
Score = 31.9 bits (69), Expect = 6.9
Identities = 46/261 (17%), Positives = 104/261 (39%), Gaps = 10/261 (3%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEE-EKASLIEQHKRDERAVSDMEDXXXXXXXXX 159
A I +L +V+ + KE Q E+ K +E + ++ E
Sbjct: 636 AMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSR 695
Query: 160 XXXKDEFNTAAKEHKDL--KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+D + ++ + + K+ D K+ + + L+ + + EM++ +
Sbjct: 696 AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 755
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEY 273
L + L + EV L+K+L+++ + ++ EK E + SKLKE
Sbjct: 756 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 815
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
E++ Q ++ ++ E E T L++ E+ + + + +E++ ++
Sbjct: 816 EKEKVHSEVVQIRSEVSQV--KREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYA 873
Query: 334 EALQPVQLELHEAKVKLSSVE 354
E+ ++ E + K+ S E
Sbjct: 874 ESSSKLE-EDKDKKINEMSKE 893
>AY237537-1|AAP04414.1| 1335|Homo sapiens KIF27B protein.
Length = 1335
Score = 51.2 bits (117), Expect = 1e-05
Identities = 99/462 (21%), Positives = 194/462 (41%), Gaps = 44/462 (9%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIR-KEMQILFEEEKASLIEQHKR-DERAVSDMEDX 151
++K DLI + V+ Q++++ +++ E+ K LIE K+ E D+ D
Sbjct: 734 KMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDV 793
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE------ANVSN 205
K + + A ++++ +E+ L + DL L+ ++ +
Sbjct: 794 AMKVKLQKEFRK-KMDAAKLRVQEIQLKTGQEE-GLKPKAEDLDACNLKRRKGSFGSIDH 851
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ---TSRAEQCTQLKNQLEKQ----- 257
++ E KK +DE ++ + + E+E L+ +L K+ S+ E Q K+ LE +
Sbjct: 852 LQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSS 911
Query: 258 ---NFEFQQVTSKLKELEYERDSYKDWQTQSKTAQK--RLCNMAE-LEKEVTRLRANERS 311
N + +++++L LE E S K+ Q Q+ TA++ ++ E L+KE +L+ +
Sbjct: 912 QALNTDSLKISTRLNLLEQEL-SEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHN 970
Query: 312 LRDAICN-KLLLEEQVH---QLTSRVEALQ-PVQLELHEAKVKLSSVESQLESWMSAARA 366
+ + + N ++L E+ H QL +EAL+ ++ + + S+ + + +S A
Sbjct: 971 VDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHN-LSRGEA 1029
Query: 367 HGVESAGALRDA-LESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLT 425
+ +E L + + L EE+ ERD +L
Sbjct: 1030 NVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESAL 1089
Query: 426 TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQ 485
K Q +RL L +E + Q L + KE GE + ++QQ
Sbjct: 1090 DHLKLQ------CDRRLTLQQKEHEQKMQLLLHHFKEQD----GEGIMETFKTYEDKIQQ 1139
Query: 486 LEKSLQGYRDLIAAHDPHAHSKALESLRNEV--TRWREEAEG 525
LEK L Y+ H E++R ++ + ++E +G
Sbjct: 1140 LEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDG 1181
Score = 35.1 bits (77), Expect = 0.75
Identities = 49/207 (23%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS---EMKKDM-DE 218
+DE + E++DLK + +E +L+ Q +++L +++ +MK+D+ E
Sbjct: 683 QDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKE 742
Query: 219 LLQALEGAQSEVEMLKKELVKQTSRAEQC----TQLKNQL-EKQNFEFQQVTSKL---KE 270
L++ A+S + ++ K AEQ + + QL E +N + V K+ KE
Sbjct: 743 LIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKE 802
Query: 271 LEYERDSYK--DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
+ D+ K + Q KT Q+ + + L+ + S +I + L+EQ
Sbjct: 803 FRKKMDAAKLRVQEIQLKTGQEEGLKPKAEDLDACNLKRRKGSF-GSIDHLQKLDEQKKW 861
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVES 355
L VE + + EL E + L E+
Sbjct: 862 LDEEVEKVLNQRQELEELEADLKKREA 888
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 42.3 bits (95), Expect = 0.005
Identities = 88/453 (19%), Positives = 183/453 (40%), Gaps = 36/453 (7%)
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N+ + H LK +++K + + ++ DK + ++ QI+E + M +L LE +
Sbjct: 234 NSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL-LIQITEKENKMKDLTFLLEES 292
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +V L+++ Q+ LK +EKQ+ +++ L+ + K + +
Sbjct: 293 RDKVNQLEEKTKLQSEN------LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LELH 344
A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE +
Sbjct: 347 IATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKN 401
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E ++K+ ++E Q +S + + L+ LG L
Sbjct: 402 EDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET--------------LL 447
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E + ++ G +L + + +E +H L+ +L +T Y +++ K+L
Sbjct: 448 YENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KDLK 503
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + LE + + + + + + R ++ E
Sbjct: 504 TELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE 563
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEEIK 580
+ T+LR + + + L++ + K L + +KQ+ +K +E Q+E K
Sbjct: 564 NLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENK 623
Query: 581 KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
LK Q + E++ + +LE K K
Sbjct: 624 ALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 42.3 bits (95), Expect = 0.005
Identities = 88/453 (19%), Positives = 183/453 (40%), Gaps = 36/453 (7%)
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N+ + H LK +++K + + ++ DK + ++ QI+E + M +L LE +
Sbjct: 234 NSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL-LIQITEKENKMKDLTFLLEES 292
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +V L+++ Q+ LK +EKQ+ +++ L+ + K + +
Sbjct: 293 RDKVNQLEEKTKLQSEN------LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LELH 344
A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE +
Sbjct: 347 IATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKN 401
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E ++K+ ++E Q +S + + L+ LG L
Sbjct: 402 EDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET--------------LL 447
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E + ++ G +L + + +E +H L+ +L +T Y +++ K+L
Sbjct: 448 YENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KDLK 503
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + LE + + + + + + R ++ E
Sbjct: 504 TELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE 563
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEEIK 580
+ T+LR + + + L++ + K L + +KQ+ +K +E Q+E K
Sbjct: 564 NLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENK 623
Query: 581 KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
LK Q + E++ + +LE K K
Sbjct: 624 ALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 42.3 bits (95), Expect = 0.005
Identities = 88/453 (19%), Positives = 183/453 (40%), Gaps = 36/453 (7%)
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N+ + H LK +++K + + ++ DK + ++ QI+E + M +L LE +
Sbjct: 234 NSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL-LIQITEKENKMKDLTFLLEES 292
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +V L+++ Q+ LK +EKQ+ +++ L+ + K + +
Sbjct: 293 RDKVNQLEEKTKLQSEN------LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LELH 344
A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE +
Sbjct: 347 IATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKN 401
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E ++K+ ++E Q +S + + L+ LG L
Sbjct: 402 EDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET--------------LL 447
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E + ++ G +L + + +E +H L+ +L +T Y +++ K+L
Sbjct: 448 YENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KDLK 503
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + LE + + + + + + R ++ E
Sbjct: 504 TELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE 563
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEEIK 580
+ T+LR + + + L++ + K L + +KQ+ +K +E Q+E K
Sbjct: 564 NLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENK 623
Query: 581 KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
LK Q + E++ + +LE K K
Sbjct: 624 ALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 51.2 bits (117), Expect = 1e-05
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Query: 221 QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
Q LE + ++++L EL K++S E+ T+L N E + E ++V + + L YE ++
Sbjct: 396 QRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEK 455
Query: 281 WQTQSKTAQKRLCNMAEL-EKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVE--ALQ 337
+ K ++ L + + EKEV L E L ++ ++V L + +E L+
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDL---EIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 338 PVQLELHEAKVKLSSVE-SQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXX 396
+L H K+ L + E +Q S M+ + E + E L
Sbjct: 513 NTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQL 572
Query: 397 XXXXXHLTEEVAT----LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSY 452
++ EE+ +K + DK+ N+L +N+ I LQ+ + ++ +
Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAE 632
Query: 453 RQQLDCYE 460
+QL+ YE
Sbjct: 633 SKQLNVYE 640
Score = 42.3 bits (95), Expect = 0.005
Identities = 88/453 (19%), Positives = 183/453 (40%), Gaps = 36/453 (7%)
Query: 167 NTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
N+ + H LK +++K + + ++ DK + ++ QI+E + M +L LE +
Sbjct: 234 NSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL-LIQITEKENKMKDLTFLLEES 292
Query: 227 QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSK 286
+ +V L+++ Q+ LK +EKQ+ +++ L+ + K + +
Sbjct: 293 RDKVNQLEEKTKLQSEN------LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 287 TAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ--LELH 344
A K +C + E EKE T++ E S + + ++ E + S E L+ Q LE +
Sbjct: 347 IATKTICQLTE-EKE-TQM---EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKN 401
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E ++K+ ++E Q +S + + L+ LG L
Sbjct: 402 EDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET--------------LL 447
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
E + ++ G +L + + +E +H L+ +L +T Y +++ K+L
Sbjct: 448 YENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEV----KDLK 503
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + LE + + + + + + R ++ E
Sbjct: 504 TELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE 563
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQI---SKELEAAQEEIK 580
+ T+LR + + + L++ + K L + +KQ+ +K +E Q+E K
Sbjct: 564 NLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENK 623
Query: 581 KLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
LK Q + E++ + +LE K K
Sbjct: 624 ALKKKGTAESKQLNVYEIKVNKLELELESAKQK 656
Score = 40.3 bits (90), Expect = 0.020
Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%)
Query: 127 FEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTD 186
FE SL E + +++ + ED E K L N + E +
Sbjct: 380 FETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTK----LTNNKEVELEE 435
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--- 243
L K + + K+ LL N + E+K EL+ L+ + EV L+ +L T+
Sbjct: 436 LKKVLGE-KETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQY 494
Query: 244 -AEQCTQLKNQLEKQNFEFQQVTSKLKELEYER----DSYKDWQTQSKTAQKRLCNMAEL 298
+++ LK +LE + + ++TS +L E D + K Q+ + N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQ 554
Query: 299 E----KEVTRLRANERSLRDAI 316
E K++ L+ E LR+ +
Sbjct: 555 EERMLKQIENLQETETQLRNEL 576
Score = 39.5 bits (88), Expect = 0.035
Identities = 52/283 (18%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
+ K L ++L +++ ++ N++ +E++ + E K +L+ ++K+ E+ +++
Sbjct: 404 QLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGE-KETLLYENKQFEKIAEELKG 462
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKAN---WDKEKTDLHKQIADLKDKLLE-ANVSNK 206
+ E + + + + + KE DL ++ + K K E + NK
Sbjct: 463 TEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNK 522
Query: 207 DQIS--EMKKDMDELLQALEGAQSEVEMLKKE---LVKQTSRAEQC-TQLKNQLEKQNFE 260
+ E+ ++ ++ L+ Q ++ KK+ ++KQ ++ TQL+N+LE E
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 261 FQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR---LRANERSLRDAI 316
+Q ++K +L+ ++ + + Q + K + + + K + + + + ++ +
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 317 CNKLLLE-EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
NKL LE E Q E Q E+ + K+ ++ ++E
Sbjct: 643 VNKLELELESAKQKFG--EITDTYQKEIEDKKISEENLLEEVE 683
Score = 35.9 bits (79), Expect = 0.43
Identities = 57/280 (20%), Positives = 112/280 (40%), Gaps = 21/280 (7%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKE-------MQILFEEEKASLIEQHKRDER 143
E K LK +L K + T+L S N KE M + + ++ + K++ER
Sbjct: 498 EVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 144 AVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEK---TDLHKQIADLKDKLLE 200
+ +E+ + ++ ++K DK + +L KQ+ + + E
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL-KNQLEKQNF 259
NK +KK + L + +V L+ EL + + T + ++E +
Sbjct: 618 LQQENK----ALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKI 673
Query: 260 EFQQVTSKLKELEYERDSYKDWQTQ-SKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
+ + ++++ + D Q + K Q ++ M L ++ RD+
Sbjct: 674 SEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDS--- 730
Query: 319 KLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+L L + Q S + A +++EL K +L SV+ QLE
Sbjct: 731 ELGLYKSKEQEQSSLRA--SLEIELSNLKAELLSVKKQLE 768
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 51.2 bits (117), Expect = 1e-05
Identities = 72/349 (20%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 129 EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH 188
+EKA L E+++ + + ++D A+ E +D+K ++ +L+
Sbjct: 592 KEKAFLFEKYQEAQEEIMKLKDTLKSQMT---------QEASDEAEDMKEAMNRMIDELN 642
Query: 189 KQIADLKDKLLEANV---------SNKDQISEM--KKDMDELLQALEGAQSEVEMLKKEL 237
KQ+++L EA S +D +E K + ++L+Q ++++ E E+
Sbjct: 643 KQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEM 702
Query: 238 VKQTSRA-EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM- 295
Q S+ + TQLK ++ Q +T L+ + R + K+ + + ++ L +
Sbjct: 703 KSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKE 762
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVES 355
E+ K +L + ++ DA+ + E+ L S V L E + K K+ S
Sbjct: 763 VEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVV 822
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
Q+ S +S + E+ L + E + E + L+ ++D
Sbjct: 823 QIRSEVSQVKRE-KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKD 881
Query: 416 KATGKLNDLT-TVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL 463
K K+N+++ V K +E+L Q + +R S QQL+ ++++
Sbjct: 882 K---KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQS--QQLEALQQQV 925
Score = 46.4 bits (105), Expect = 3e-04
Identities = 46/203 (22%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI----------SEMKKDMD 217
TAAKE ++ +N + ++A L+ +LLE + D + S ++ ++
Sbjct: 742 TAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 801
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ----LEKQNFEFQQVTSKLKELEY 273
L L+ + E E + E+V+ S Q + K L+ + E ++ K ++ +
Sbjct: 802 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQE 861
Query: 274 ERDSYKDW-QTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E K + ++ SK + + + E+ KEVT+L+ SL + + Q QL +
Sbjct: 862 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 921
Query: 333 VEALQPVQLELHEAKVKLSSVES 355
+ ++ +Q +L E K + V S
Sbjct: 922 QQQVKQLQNQLAECKKQHQEVIS 944
Score = 40.7 bits (91), Expect = 0.015
Identities = 85/456 (18%), Positives = 182/456 (39%), Gaps = 37/456 (8%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEML 233
+DL+ + + + + +L+ + E N +ISE D L Q L+ QS+ E
Sbjct: 439 QDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD---LSQKLKETQSKYEEA 495
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLC 293
KE++ + + ++ + F ++ +E+ + ++ +S+ ++++
Sbjct: 496 MKEVLSVQKQMKLGLVSPESMDNYS-HFHELRVTEEEINVLKQDLQNALEESERNKEKVR 554
Query: 294 NMAE--LEKE---VTRLRANE-RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
+ E +E+E V + E ++ + C+ ++E + E Q Q E+ + K
Sbjct: 555 ELEEKLVEREKGTVIKPPVEEYEEMKSSYCS--VIENMNKEKAFLFEKYQEAQEEIMKLK 612
Query: 348 VKLSSVESQLESWMSAARAHGVESAGALRDALESALG-XXXXXXXXXXXXXXXXXHLTEE 406
+++SQ+ S E+ + D L + + E
Sbjct: 613 ---DTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLE 669
Query: 407 VATLKYERDKATGKLNDLTTV-RKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTV 465
T +Y KL LT V R E + ++ + V E +Q +D +KE +V
Sbjct: 670 DVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDA-QKENSV 728
Query: 466 TLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEG 525
++ E + L +++E+ + ++ H SK +E + E E+A
Sbjct: 729 SI--TEHLQVITTLRTAAKEMEEKISNLKE-------HLASKEVEVAKLEKQLLEEKA-- 777
Query: 526 ARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK-- 583
A D R+ + L +SLE + VL + + ++++ E+ + E+ ++K
Sbjct: 778 AMTDAMVPRSSYEKLQSSLE---SEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKRE 834
Query: 584 ---VALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
+ + + EL Q QQ + ++KRY+
Sbjct: 835 KENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYA 870
Score = 32.7 bits (71), Expect = 4.0
Identities = 37/182 (20%), Positives = 74/182 (40%), Gaps = 7/182 (3%)
Query: 91 ETKRLKIDLIAAKAQITKL----ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS 146
E +L+ L+ KA +T S Q ++ E+ +L + K S+ E+ K V
Sbjct: 764 EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ 823
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLH--KQIADLKDKLLEANVS 204
+ + + +E +L + + + +L K+ A+ KL E
Sbjct: 824 -IRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDK 882
Query: 205 NKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+++S+ + E L +L K++ + + +Q QL+NQL + + Q+V
Sbjct: 883 KINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEV 942
Query: 265 TS 266
S
Sbjct: 943 IS 944
Score = 31.9 bits (69), Expect = 6.9
Identities = 46/261 (17%), Positives = 104/261 (39%), Gaps = 10/261 (3%)
Query: 101 AAKAQITKLESRVNHQHTIRKEMQILFEE-EKASLIEQHKRDERAVSDMEDXXXXXXXXX 159
A I +L +V+ + KE Q E+ K +E + ++ E
Sbjct: 633 AMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSR 692
Query: 160 XXXKDEFNTAAKEHKDL--KANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+D + ++ + + K+ D K+ + + L+ + + EM++ +
Sbjct: 693 AKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKIS 752
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK----QNFEFQQVTSKLKELEY 273
L + L + EV L+K+L+++ + ++ EK E + SKLKE
Sbjct: 753 NLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVK 812
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRV 333
E++ Q ++ ++ E E T L++ E+ + + + +E++ ++
Sbjct: 813 EKEKVHSEVVQIRSEVSQV--KREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYA 870
Query: 334 EALQPVQLELHEAKVKLSSVE 354
E+ ++ E + K+ S E
Sbjct: 871 ESSSKLE-EDKDKKINEMSKE 890
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 51.2 bits (117), Expect = 1e-05
Identities = 97/449 (21%), Positives = 188/449 (41%), Gaps = 30/449 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKL-----LEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+N DKE L+++I LK+K+ LE + + + + ++D + L+ LE V
Sbjct: 481 SNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ 540
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL 292
K+EL KQ A + +LK+Q ++ QQ L+E + + + Q + ++L
Sbjct: 541 EKEELHKQLVEASE--RLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQL 598
Query: 293 CNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E+E ++ A + +R A + LE Q+ + EA + +L H
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVA--EASKERKLREHSENF-CK 655
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALG--XXXXXXXXXXXXXXXXXHLTEEVAT 409
+ES+LE+ G + + + H+ E
Sbjct: 656 QMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNV 715
Query: 410 LKYERDKATGKL---NDLTTVR-KNQESLIHRLQKRLLLVTRERDSY-RQQLDCYEKELT 464
K D + +L ++ ++ K ++S R + V +D Y R++ +++
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
+T E+ V L+A+ +QLE LQ DL A + AH +A + E+ +W + +
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQ---DLAAKKESVAHWEAQIA---EIIQWVSDEK 829
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
AR + L ++ +T LE + + + T +P + ++ ++ A E L+
Sbjct: 830 DARGYLQALASK---MTEELEAL-RSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEA 885
Query: 585 ALREGGAQADPEELQQMRQQLENSRIKLK 613
+R Q EEL++++ KLK
Sbjct: 886 EIR--AKQLVQEELRKVKDANLTLESKLK 912
Score = 41.9 bits (94), Expect = 0.006
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
++++N KD+ ++++D++ LQ +E + + L++E ++ + + ++ TQ L
Sbjct: 418 IMQSNTLTKDE--DVQRDLEHSLQ-MEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGS 474
Query: 258 NFEFQQVT--SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE----VTRLRANERS 311
+ ++K+L E + K+ S +++L + L +E RLR E+
Sbjct: 475 SRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQ 534
Query: 312 LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE-SQLESWMSAARAHGVE 370
R K L +Q+ + + R+++ + H+ + KL+ E S+L M+ RA +
Sbjct: 535 HRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQR-KLALQEFSELNERMAELRAQKQK 593
Query: 371 SAGALRDALE 380
+ LRD E
Sbjct: 594 VSRQLRDKEE 603
Score = 41.5 bits (93), Expect = 0.009
Identities = 56/277 (20%), Positives = 118/277 (42%), Gaps = 27/277 (9%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
++ A ++ + + +RKE++ ++ A ++ K E + + +
Sbjct: 604 EMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEA 663
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
A EH+ K K++L K++ +++L+ S+ ++ +KK++
Sbjct: 664 LKVKQGGRGAGATLEHQQ---EISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVH 720
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ Q E+ MLK +L K++ E+ N E ++ +K+ +YER+
Sbjct: 721 DSESHQLALQKEILMLKDKLE------------KSKRERHN-EMEEAVGTIKD-KYERER 766
Query: 278 YKDWQTQSK-TAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-HQLTSRVE 334
+ K TA+ ++LC+ V +L A R L D + + +E V H E
Sbjct: 767 AMLFDENKKLTAENEKLCSF------VDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAE 820
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+Q V E +A+ L ++ S++ + A R+ + S
Sbjct: 821 IIQWVSDE-KDARGYLQALASKMTEELEALRSSSLGS 856
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 20/252 (7%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA-EQCT 248
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K++ + + +Q
Sbjct: 704 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 763
Query: 249 QLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEKEVTR 304
++ N K+ E ++ L+E D+ D Q Q +K R+ + E +E +
Sbjct: 764 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 823
Query: 305 LRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL---ESW 360
+ A E L + E+QV +L + A++ V+ EL K KLSS + L E+
Sbjct: 824 ITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAEKETH 880
Query: 361 MSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDK 416
++ RA H E ++AL +A+ EEVA LK E+D+
Sbjct: 881 LTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKREKDR 939
Query: 417 ATGKLNDLTTVR 428
+L T R
Sbjct: 940 LVQQLKQQTQNR 951
Score = 44.4 bits (100), Expect = 0.001
Identities = 111/537 (20%), Positives = 225/537 (41%), Gaps = 43/537 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFE-----EEKASLIEQHKRDERA- 144
E R +L+A + TKLE+ N ++ +++L E E++A++++ R
Sbjct: 446 ELSRKDTELLALQ---TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 145 VSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD-KEK--TDLHKQIADLKDKLL-- 199
+ + E +E T A E DLK D KE+ L K+I +L+++L
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 200 EANVSN-KDQISEMKKDM---DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
E +S+ K+++ ++ D D L LE A +E E + L +Q R E+ + + +++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER--EKQEEID 620
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
+ + + K+ L+ + + K L + + L+K+ +RL+ E +L
Sbjct: 621 NYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS-SGLKKD-SRLKTLEIALEQK 678
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGAL 375
L +E QL EA + E ++ +E ++ + + E L
Sbjct: 679 KEECLKMES---QLKKAHEAALEARAS-PEMSDRIQHLEREITRYKDESSKAQAE-VDRL 733
Query: 376 RDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLI 435
+ L+ ++VA LK++ K + + +E +
Sbjct: 734 LEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNL 793
Query: 436 HRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRD 495
+ ++L R++D ++L+ +E +V + E SAR EK ++ +
Sbjct: 794 NDSSQQLQDSLRKKDDRIEELEEALRE-SVQITAEREMVLAQEESART-NAEKQVE---E 848
Query: 496 LIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLH 555
L+ A + + LES++ +++ ++ +T LR +R + + + +
Sbjct: 849 LLMAME--KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAA 906
Query: 556 LTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
++ A A ++S + QEE+ LK RE +QQ++QQ +N R+KL
Sbjct: 907 ISEKDANIALLELSSSKKKTQEEVAALK---RE-----KDRLVQQLKQQTQN-RMKL 954
Score = 41.1 bits (92), Expect = 0.011
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 13 VLEPFRRVINTEPPKDKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
+LE + V N + KDK A D + + L + K+KS+ + +
Sbjct: 733 LLEILKEVENEKNDKDKKIAELERQVKDQNKKVAN-LKHKEQVEKKKSA-----QMLEEA 786
Query: 73 RLRRDSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKA 132
R R D+ + + ++L+ L +I +LE + I E +++ +E++
Sbjct: 787 RRREDNLNDSS---------QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEES 837
Query: 133 SLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIA 192
+ K+ E + ME + A++ L N E+ +++
Sbjct: 838 ARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVL 896
Query: 193 DLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKN 252
++K + L A +S KD + EL + + Q EV LK+E + + +Q TQ +
Sbjct: 897 EMKQEALLAAISEKDANIALL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 952
Query: 253 QLEKQNFE 260
+L N+E
Sbjct: 953 KLMADNYE 960
Score = 37.1 bits (82), Expect = 0.18
Identities = 97/523 (18%), Positives = 210/523 (40%), Gaps = 45/523 (8%)
Query: 109 LESRVNHQHTIRKEMQILFE------EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
LE + +R+EM FE + KA +D + +S ME
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK-ISSMERGLRDLEEEIQML 408
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQ 221
K + +E ++ + ++ H + K ++ +S KD ++ ++ ++ L
Sbjct: 409 KSNGALSTEEREEEMKQMEVYRS--HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 466
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKD 280
++ +E+LK+ L T++ ++ L+ +++ ++ + L K+ + +D ++
Sbjct: 467 QFSDSKQHIEVLKESL---TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 523
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
TQ+ + E++V L+ +L++ + +K E+Q+ L RV++LQ
Sbjct: 524 KGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK---EKQMSSLKERVKSLQA-- 578
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ L+++E L A + +E RD E
Sbjct: 579 -DTTNTDTALTTLEEAL-----AEKERTIERLKEQRDRDERE------KQEEIDNYKKDL 626
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR-LQKRLLLVTRERDSYRQQLDCY 459
L E+V+ L+ + + L DL +++ SL L+K L T E +++ +C
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDL---KEHASSLASSGLKKDSRLKTLEIALEQKKEECL 683
Query: 460 EKELTVTLCGEEGAGSVAL--LSARVQQLEKSLQGYRDLIAAHDPHAHS-----KALESL 512
+ E + E + A +S R+Q LE+ + Y+D + K +E+
Sbjct: 684 KMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENE 743
Query: 513 RNEVTRWREEAEGARRDVT-KLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKE 571
+N+ + E E +D K+ + ++ + + ++ +Q+
Sbjct: 744 KNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDS 803
Query: 572 LEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKR 614
L + I++L+ ALRE Q E + Q+ E++R ++
Sbjct: 804 LRKKDDRIEELEEALRE-SVQITAEREMVLAQE-ESARTNAEK 844
>AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein.
Length = 720
Score = 51.2 bits (117), Expect = 1e-05
Identities = 67/256 (26%), Positives = 114/256 (44%), Gaps = 24/256 (9%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKK---ELVKQTSRA-- 244
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K EL TSR
Sbjct: 432 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVK 491
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEK 300
+Q ++ N K+ E ++ L+E D+ D Q Q +K R+ + E +
Sbjct: 492 DQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 551
Query: 301 EVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL-- 357
E ++ A E L + E+QV +L + A++ V+ EL K KLSS + L
Sbjct: 552 ESVQITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAE 608
Query: 358 -ESWMSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY 412
E+ ++ RA H E ++AL +A+ EEVA LK
Sbjct: 609 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKR 667
Query: 413 ERDKATGKLNDLTTVR 428
E+D+ +L T R
Sbjct: 668 EKDRLVQQLKQQTQNR 683
Score = 44.8 bits (101), Expect = 0.001
Identities = 82/387 (21%), Positives = 156/387 (40%), Gaps = 35/387 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRD----ERAV 145
K L+ D +T LE + + TI KE + E EK I+ +K+D + V
Sbjct: 302 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 361
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEH-------KDLKANWDKEKTDLHKQIADLK--- 195
S ++ K+ ++ A K L+ +++K + K + LK
Sbjct: 362 SLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 421
Query: 196 DKLLEANVSNK--DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
+ LEA S + D+I +++++ AQ+EV+ L E++K+ KN
Sbjct: 422 EAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL-EILKEVENE------KND 474
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRANERSL 312
+K+ E + +TS+ +++ + + + + + +K+ M E + L + + L
Sbjct: 475 KDKKIAELESLTSR--QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 532
Query: 313 RDAICNKL-LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA--HGV 369
+D++ K +EE L V+ ++ L + + ++ E Q+E + A +
Sbjct: 533 QDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQEL 592
Query: 370 ESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK 429
ES A + + +L HL EEV +K E A D
Sbjct: 593 ESMKAKLSSTQQSLAEKETHLTNLRAERRK--HL-EEVLEMKQEALLAAISEKDANIALL 649
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 650 ELSSSKKKTQEEVAALKREKDRLVQQL 676
Score = 39.5 bits (88), Expect = 0.035
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 5/169 (2%)
Query: 92 TKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDX 151
+++L+ L +I +LE + I E +++ +E+++ K+ E + ME
Sbjct: 529 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 588
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
+ A++ L N E+ +++ ++K + L A +S KD
Sbjct: 589 KQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVLEMKQEALLAAISEKDANIA 647
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+ EL + + Q EV LK+E + + +Q TQ + +L N+E
Sbjct: 648 LL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 692
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 51.2 bits (117), Expect = 1e-05
Identities = 67/256 (26%), Positives = 114/256 (44%), Gaps = 24/256 (9%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKK---ELVKQTSRA-- 244
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K EL TSR
Sbjct: 704 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVK 763
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEK 300
+Q ++ N K+ E ++ L+E D+ D Q Q +K R+ + E +
Sbjct: 764 DQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 823
Query: 301 EVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL-- 357
E ++ A E L + E+QV +L + A++ V+ EL K KLSS + L
Sbjct: 824 ESVQITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAE 880
Query: 358 -ESWMSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY 412
E+ ++ RA H E ++AL +A+ EEVA LK
Sbjct: 881 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKR 939
Query: 413 ERDKATGKLNDLTTVR 428
E+D+ +L T R
Sbjct: 940 EKDRLVQQLKQQTQNR 955
Score = 48.8 bits (111), Expect = 6e-05
Identities = 121/542 (22%), Positives = 225/542 (41%), Gaps = 66/542 (12%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFE-----EEKASLIEQHKRDERA- 144
E R +L+A + TKLE+ N ++ +++L E E++A++++ R
Sbjct: 446 ELSRKDTELLALQ---TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 145 VSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD-KEK--TDLHKQIADLKDKLL-- 199
+ + E +E T A E DLK D KE+ L K+I +L+++L
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 200 EANVSN-KDQISEMKKDM---DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
E +S+ K+++ ++ D D L LE A +E E + L +Q R E+ E
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER--------E 614
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
KQ +E++ + KD + + Q +++E E + L+ + SL +
Sbjct: 615 KQ-----------EEIDNYKKDLKDLKEKVSLLQG---DLSEKEASLLDLKEHASSLASS 660
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA-RAHGVESAGA 374
K SR++ L ++ L + K + +ESQL+ AA A
Sbjct: 661 GLKK----------DSRLKTL---EIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 707
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR-KNQES 433
LE + + +EV K ++DK +L LT+ + K+Q
Sbjct: 708 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNK 767
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ + + ++ S + + +E + ++ S+ R+++LE++L+
Sbjct: 768 KVANLKHKEQV--EKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRES 825
Query: 494 RDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTK 552
+ A + + ES R + EE A V +L + + L+++ + + K
Sbjct: 826 VQITAEREMVLAQE--ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EK 881
Query: 553 VLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
HLT N AE +K + + LE QE L A+ E A EL +++ + L
Sbjct: 882 ETHLT-NLRAERRKHLEEVLEMKQE---ALLAAISEKDANIALLELSSSKKKTQEEVAAL 937
Query: 613 KR 614
KR
Sbjct: 938 KR 939
Score = 44.8 bits (101), Expect = 0.001
Identities = 82/387 (21%), Positives = 156/387 (40%), Gaps = 35/387 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRD----ERAV 145
K L+ D +T LE + + TI KE + E EK I+ +K+D + V
Sbjct: 574 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 633
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEH-------KDLKANWDKEKTDLHKQIADLK--- 195
S ++ K+ ++ A K L+ +++K + K + LK
Sbjct: 634 SLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 693
Query: 196 DKLLEANVSNK--DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
+ LEA S + D+I +++++ AQ+EV+ L E++K+ KN
Sbjct: 694 EAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL-EILKEVENE------KND 746
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRANERSL 312
+K+ E + +TS+ +++ + + + + + +K+ M E + L + + L
Sbjct: 747 KDKKIAELESLTSR--QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 804
Query: 313 RDAICNKL-LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA--HGV 369
+D++ K +EE L V+ ++ L + + ++ E Q+E + A +
Sbjct: 805 QDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQEL 864
Query: 370 ESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK 429
ES A + + +L HL EEV +K E A D
Sbjct: 865 ESMKAKLSSTQQSLAEKETHLTNLRAERRK--HL-EEVLEMKQEALLAAISEKDANIALL 921
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 922 ELSSSKKKTQEEVAALKREKDRLVQQL 948
Score = 39.5 bits (88), Expect = 0.035
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 5/169 (2%)
Query: 92 TKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDX 151
+++L+ L +I +LE + I E +++ +E+++ K+ E + ME
Sbjct: 801 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 860
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
+ A++ L N E+ +++ ++K + L A +S KD
Sbjct: 861 KQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVLEMKQEALLAAISEKDANIA 919
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+ EL + + Q EV LK+E + + +Q TQ + +L N+E
Sbjct: 920 LL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 964
Score = 37.5 bits (83), Expect = 0.14
Identities = 98/513 (19%), Positives = 209/513 (40%), Gaps = 50/513 (9%)
Query: 109 LESRVNHQHTIRKEMQILFE------EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
LE + +R+EM FE + KA +D + +S ME
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK-ISSMERGLRDLEEEIQML 408
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQ 221
K + +E ++ + ++ H + K ++ +S KD ++ ++ ++ L
Sbjct: 409 KSNGALSTEEREEEMKQMEVYRS--HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 466
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKD 280
++ +E+LK+ L T++ ++ L+ +++ ++ + L K+ + +D ++
Sbjct: 467 QFSDSKQHIEVLKESL---TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 523
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
TQ+ + E++V L+ +L++ + +K E+Q+ L RV++LQ
Sbjct: 524 KGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK---EKQMSSLKERVKSLQA-- 578
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ L+++E L A + +E RD E
Sbjct: 579 -DTTNTDTALTTLEEAL-----AEKERTIERLKEQRDRDERE------KQEEIDNYKKDL 626
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR-LQKRLLLVTRERDSYRQQLDCY 459
L E+V+ L+ + + L DL +++ SL L+K L T E +++ +C
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDL---KEHASSLASSGLKKDSRLKTLEIALEQKKEECL 683
Query: 460 EKELTVTLCGEEGAGSVAL--LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+ E + E + A +S R+Q LE+ + Y+D SKA + + +
Sbjct: 684 KMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD--------ESSKAQAEV-DRLL 734
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK--QISKELEAA 575
+E E + D K + + LT S + KV +L + E +K Q+ +E
Sbjct: 735 EILKEVENEKNDKDKKIAELESLT-SRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 793
Query: 576 QEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
++ + L++ + D + ++++ + L S
Sbjct: 794 EDNLNDSSQQLQDSLRKKD-DRIEELEEALRES 825
>AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein.
Length = 1313
Score = 51.2 bits (117), Expect = 1e-05
Identities = 101/478 (21%), Positives = 187/478 (39%), Gaps = 32/478 (6%)
Query: 100 IAAKAQITKLESRVNHQHTIRKEMQI-LFEEEKASLIEQHKRDERAVSDMEDXXXXXXXX 158
+ K + K E R ++E+Q +E EK R+E + ED
Sbjct: 811 LVEKHTLEKEELRKELLEKHQRELQEGRYESEKLQQENSILRNEITTLNEEDSISNLKLG 870
Query: 159 XXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQ 208
E + K A K +L KQI++LK K L + N N+++
Sbjct: 871 TLNGSQEEMQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEK 930
Query: 209 ISEMKKDMDELL--QALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVT 265
+ E+ + + E+L + E S +E ++E E+C Q + E +V
Sbjct: 931 LQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVK 990
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEE 324
+ ++ E KD + + R ++++ +++++ L NE+ L++ K L E
Sbjct: 991 IQTHIVQQENHLLKD-ELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSE 1045
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
+++ ++ ++ + K + S E Q S S A E L D +++
Sbjct: 1046 ELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNL 1104
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
L +EV +L + A GK S +H QKRL
Sbjct: 1105 QMSRMKSDLRVTQQEKEALKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSW 1162
Query: 445 VTRER-DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAA 499
+ + QQL E E T+ + + +V+QLE +L Q + +
Sbjct: 1163 DKLDHLMNEEQQLLWQENERLQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSGT 1221
Query: 500 HDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHL 556
+P K SL+ E ++++E A R V+++ + +++L T LE G + K + L
Sbjct: 1222 MNPTEQEKL--SLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL 1277
Score = 43.2 bits (97), Expect = 0.003
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 29/254 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1039 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1097
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1098 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1153
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E Q+ V+ K EL T E+ QL++ L
Sbjct: 1154 HNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAEL---THSREKVRQLESNLLP 1210
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1211 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1270
Query: 313 RDAICNKLLLEEQV 326
+ ++ L+EQ+
Sbjct: 1271 KK---KQVKLDEQL 1281
Score = 32.7 bits (71), Expect = 4.0
Identities = 37/176 (21%), Positives = 82/176 (46%), Gaps = 14/176 (7%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 687 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 742
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 743 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 802
Query: 287 TAQKRLCNMAE---LEKEVTR---LRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
Q++L ++ E LEKE R L ++R L++ L+++ L + + L
Sbjct: 803 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGRYESEKLQQENSILRNEITTL 858
Score = 32.3 bits (70), Expect = 5.3
Identities = 32/141 (22%), Positives = 71/141 (50%), Gaps = 16/141 (11%)
Query: 187 LHKQIADLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTS 242
L ++ K+ + +A +++ K +I + + +D++++ E +S++ E LK + +
Sbjct: 384 LENELLVTKNSIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVD 443
Query: 243 RAEQCTQLKNQ--LEKQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ +N+ L K + E+++ + LK EL ER+ Q + ++RL ELE
Sbjct: 444 DHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELE 494
Query: 300 KEVTRLRANERSLRDAICNKL 320
+E+ + + E +RD + L
Sbjct: 495 QEIEKAKTEENYIRDRLALSL 515
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 51.2 bits (117), Expect = 1e-05
Identities = 97/449 (21%), Positives = 188/449 (41%), Gaps = 30/449 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKL-----LEANVSNKDQISEMKKDMDELLQALEGAQSEVEM 232
+N DKE L+++I LK+K+ LE + + + + ++D + L+ LE V
Sbjct: 530 SNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ 589
Query: 233 LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL 292
K+EL KQ A + +LK+Q ++ QQ L+E + + + Q + ++L
Sbjct: 590 EKEELHKQLVEASE--RLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQL 647
Query: 293 CNM-AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLS 351
+ E+E ++ A + +R A + LE Q+ + EA + +L H
Sbjct: 648 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVA--EASKERKLREHSENF-CK 704
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALG--XXXXXXXXXXXXXXXXXHLTEEVAT 409
+ES+LE+ G + + + H+ E
Sbjct: 705 QMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNV 764
Query: 410 LKYERDKATGKL---NDLTTVR-KNQESLIHRLQKRLLLVTRERDSY-RQQLDCYEKELT 464
K D + +L ++ ++ K ++S R + V +D Y R++ +++
Sbjct: 765 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 824
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
+T E+ V L+A+ +QLE LQ DL A + AH +A + E+ +W + +
Sbjct: 825 LTAENEKLCSFVDKLTAQNRQLEDELQ---DLAAKKESVAHWEAQIA---EIIQWVSDEK 878
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
AR + L ++ +T LE + + + T +P + ++ ++ A E L+
Sbjct: 879 DARGYLQALASK---MTEELEAL-RSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEA 934
Query: 585 ALREGGAQADPEELQQMRQQLENSRIKLK 613
+R Q EEL++++ KLK
Sbjct: 935 EIR--AKQLVQEELRKVKDANLTLESKLK 961
Score = 41.9 bits (94), Expect = 0.006
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 198 LLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQ 257
++++N KD+ ++++D++ LQ +E + + L++E ++ + + ++ TQ L
Sbjct: 467 IMQSNTLTKDE--DVQRDLEHSLQ-MEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGS 523
Query: 258 NFEFQQVT--SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKE----VTRLRANERS 311
+ ++K+L E + K+ S +++L + L +E RLR E+
Sbjct: 524 SRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQ 583
Query: 312 LRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVE-SQLESWMSAARAHGVE 370
R K L +Q+ + + R+++ + H+ + KL+ E S+L M+ RA +
Sbjct: 584 HRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQR-KLALQEFSELNERMAELRAQKQK 642
Query: 371 SAGALRDALE 380
+ LRD E
Sbjct: 643 VSRQLRDKEE 652
Score = 41.5 bits (93), Expect = 0.009
Identities = 56/277 (20%), Positives = 118/277 (42%), Gaps = 27/277 (9%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
++ A ++ + + +RKE++ ++ A ++ K E + + +
Sbjct: 653 EMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEA 712
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
A EH+ K K++L K++ +++L+ S+ ++ +KK++
Sbjct: 713 LKVKQGGRGAGATLEHQQ---EISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVH 769
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+ Q E+ MLK +L K++ E+ N E ++ +K+ +YER+
Sbjct: 770 DSESHQLALQKEILMLKDKLE------------KSKRERHN-EMEEAVGTIKD-KYERER 815
Query: 278 YKDWQTQSK-TAQ-KRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQV-HQLTSRVE 334
+ K TA+ ++LC+ V +L A R L D + + +E V H E
Sbjct: 816 AMLFDENKKLTAENEKLCSF------VDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAE 869
Query: 335 ALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVES 371
+Q V E +A+ L ++ S++ + A R+ + S
Sbjct: 870 IIQWVSDE-KDARGYLQALASKMTEELEALRSSSLGS 905
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 51.2 bits (117), Expect = 1e-05
Identities = 67/256 (26%), Positives = 114/256 (44%), Gaps = 24/256 (9%)
Query: 193 DLKDKL--LEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKK---ELVKQTSRA-- 244
++ D++ LE ++ KD+ S+ + ++D LL+ L+ ++E K EL TSR
Sbjct: 715 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVK 774
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD--WQTQSKTAQK--RLCNMAELEK 300
+Q ++ N K+ E ++ L+E D+ D Q Q +K R+ + E +
Sbjct: 775 DQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 834
Query: 301 EVTRLRAN-ERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL-- 357
E ++ A E L + E+QV +L + A++ V+ EL K KLSS + L
Sbjct: 835 ESVQITAEREMVLAQEESARTNAEKQVEEL---LMAMEKVKQELESMKAKLSSTQQSLAE 891
Query: 358 -ESWMSAARA----HGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKY 412
E+ ++ RA H E ++AL +A+ EEVA LK
Sbjct: 892 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK-TQEEVAALKR 950
Query: 413 ERDKATGKLNDLTTVR 428
E+D+ +L T R
Sbjct: 951 EKDRLVQQLKQQTQNR 966
Score = 48.8 bits (111), Expect = 6e-05
Identities = 121/542 (22%), Positives = 225/542 (41%), Gaps = 66/542 (12%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFE-----EEKASLIEQHKRDERA- 144
E R +L+A + TKLE+ N ++ +++L E E++A++++ R
Sbjct: 457 ELSRKDTELLALQ---TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 513
Query: 145 VSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWD-KEK--TDLHKQIADLKDKLL-- 199
+ + E +E T A E DLK D KE+ L K+I +L+++L
Sbjct: 514 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 573
Query: 200 EANVSN-KDQISEMKKDM---DELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLE 255
E +S+ K+++ ++ D D L LE A +E E + L +Q R E+ E
Sbjct: 574 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER--------E 625
Query: 256 KQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDA 315
KQ +E++ + KD + + Q +++E E + L+ + SL +
Sbjct: 626 KQ-----------EEIDNYKKDLKDLKEKVSLLQG---DLSEKEASLLDLKEHASSLASS 671
Query: 316 ICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAA-RAHGVESAGA 374
K SR++ L ++ L + K + +ESQL+ AA A
Sbjct: 672 GLKK----------DSRLKTL---EIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 718
Query: 375 LRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR-KNQES 433
LE + + +EV K ++DK +L LT+ + K+Q
Sbjct: 719 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNK 778
Query: 434 LIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGY 493
+ L+ + + ++ S + + +E + ++ S+ R+++LE++L+
Sbjct: 779 KVANLKHKEQV--EKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRES 836
Query: 494 RDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDV-TKLRTQRDLLTASLERIGPQTK 552
+ A + + ES R + EE A V +L + + L+++ + + K
Sbjct: 837 VQITAEREMVLAQE--ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EK 892
Query: 553 VLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKL 612
HLT N AE +K + + LE QE L A+ E A EL +++ + L
Sbjct: 893 ETHLT-NLRAERRKHLEEVLEMKQE---ALLAAISEKDANIALLELSSSKKKTQEEVAAL 948
Query: 613 KR 614
KR
Sbjct: 949 KR 950
Score = 44.8 bits (101), Expect = 0.001
Identities = 82/387 (21%), Positives = 156/387 (40%), Gaps = 35/387 (9%)
Query: 93 KRLKIDLIAAKAQITKLESRV-NHQHTIR--KEMQILFEEEKASLIEQHKRD----ERAV 145
K L+ D +T LE + + TI KE + E EK I+ +K+D + V
Sbjct: 585 KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 644
Query: 146 SDMEDXXXXXXXXXXXXKDEFNTAAKEH-------KDLKANWDKEKTDLHKQIADLK--- 195
S ++ K+ ++ A K L+ +++K + K + LK
Sbjct: 645 SLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 704
Query: 196 DKLLEANVSNK--DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ 253
+ LEA S + D+I +++++ AQ+EV+ L E++K+ KN
Sbjct: 705 EAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL-EILKEVENE------KND 757
Query: 254 LEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRANERSL 312
+K+ E + +TS+ +++ + + + + + +K+ M E + L + + L
Sbjct: 758 KDKKIAELESLTSR--QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 815
Query: 313 RDAICNKL-LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARA--HGV 369
+D++ K +EE L V+ ++ L + + ++ E Q+E + A +
Sbjct: 816 QDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQEL 875
Query: 370 ESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRK 429
ES A + + +L HL EEV +K E A D
Sbjct: 876 ESMKAKLSSTQQSLAEKETHLTNLRAERRK--HL-EEVLEMKQEALLAAISEKDANIALL 932
Query: 430 NQESLIHRLQKRLLLVTRERDSYRQQL 456
S + Q+ + + RE+D QQL
Sbjct: 933 ELSSSKKKTQEEVAALKREKDRLVQQL 959
Score = 39.5 bits (88), Expect = 0.035
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 5/169 (2%)
Query: 92 TKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDX 151
+++L+ L +I +LE + I E +++ +E+++ K+ E + ME
Sbjct: 812 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 871
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISE 211
+ A++ L N E+ +++ ++K + L A +S KD
Sbjct: 872 KQELESMKAKLSSTQQSLAEKETHL-TNLRAERRKHLEEVLEMKQEALLAAISEKDANIA 930
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFE 260
+ EL + + Q EV LK+E + + +Q TQ + +L N+E
Sbjct: 931 LL----ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 975
Score = 37.5 bits (83), Expect = 0.14
Identities = 98/513 (19%), Positives = 209/513 (40%), Gaps = 50/513 (9%)
Query: 109 LESRVNHQHTIRKEMQILFE------EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXX 162
LE + +R+EM FE + KA +D + +S ME
Sbjct: 361 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSK-ISSMERGLRDLEEEIQML 419
Query: 163 KDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQ 221
K + +E ++ + ++ H + K ++ +S KD ++ ++ ++ L
Sbjct: 420 KSNGALSTEEREEEMKQMEVYRS--HSKFMKNKIGQVKQELSRKDTELLALQTKLETLTN 477
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL-KELEYERDSYKD 280
++ +E+LK+ L T++ ++ L+ +++ ++ + L K+ + +D ++
Sbjct: 478 QFSDSKQHIEVLKESL---TAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 534
Query: 281 WQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQ 340
TQ+ + E++V L+ +L++ + +K E+Q+ L RV++LQ
Sbjct: 535 KGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK---EKQMSSLKERVKSLQA-- 589
Query: 341 LELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXX 400
+ L+++E L A + +E RD E
Sbjct: 590 -DTTNTDTALTTLEEAL-----AEKERTIERLKEQRDRDERE------KQEEIDNYKKDL 637
Query: 401 XHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR-LQKRLLLVTRERDSYRQQLDCY 459
L E+V+ L+ + + L DL +++ SL L+K L T E +++ +C
Sbjct: 638 KDLKEKVSLLQGDLSEKEASLLDL---KEHASSLASSGLKKDSRLKTLEIALEQKKEECL 694
Query: 460 EKELTVTLCGEEGAGSVAL--LSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVT 517
+ E + E + A +S R+Q LE+ + Y+D SKA + + +
Sbjct: 695 KMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD--------ESSKAQAEV-DRLL 745
Query: 518 RWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQK--QISKELEAA 575
+E E + D K + + LT S + KV +L + E +K Q+ +E
Sbjct: 746 EILKEVENEKNDKDKKIAELESLT-SRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 804
Query: 576 QEEIKKLKVALREGGAQADPEELQQMRQQLENS 608
++ + L++ + D + ++++ + L S
Sbjct: 805 EDNLNDSSQQLQDSLRKKD-DRIEELEEALRES 836
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 51.2 bits (117), Expect = 1e-05
Identities = 104/528 (19%), Positives = 214/528 (40%), Gaps = 52/528 (9%)
Query: 98 DLIAAKAQITKLESRVNHQ-HTI-----RKE---MQILFEEEKASLIEQHKRDERAVSDM 148
DL+ AK QI + ++ Q H + +KE MQI F +EK + E + + S+
Sbjct: 262 DLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNK 321
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQ 208
E+ +E NT E + + T K + +L++++++ N +
Sbjct: 322 EEIQEKETII-----EELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN----QE 372
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
I MK ++ Q + E++ L + + R + +Q + + Q E Q+ KL
Sbjct: 373 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIV-QRME-QETQRKL 430
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
++L E D Q + +MA++E+ TR + + + N + E+Q+
Sbjct: 431 EQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENALRSYSNITVNEDQI-- 488
Query: 329 LTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXX 388
+ + + ++E +KL SQ E + +E AL+ LE +
Sbjct: 489 --------KLMNVAINELNIKLQDTNSQKEK-LKEELGLILEEKCALQRQLEDLV----- 534
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR- 447
+ T+ + K L+TV + ++ + R L +
Sbjct: 535 -----EELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKH 589
Query: 448 --ERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAH 505
E +Y+ +L+ EKE L A L QL S + + H
Sbjct: 590 EAEVTNYKIKLEMLEKEKNAVL-DRMAESQEAELERLSTQLLFSHEEELSKLKEDLEIEH 648
Query: 506 SKALESLRNEV-TRWREEAEGARRDVT-KLRTQR----DLLTASLERIGPQTKVLHLTNN 559
++E L++ + ++++ +G + +++ K+ T + +L+T + I +K+ L +
Sbjct: 649 RISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS 708
Query: 560 PAAEAQKQISKELEAAQEEIKKLKVALREGGA-QADPEELQQMRQQLE 606
++++ ++ Q+EI+ L+ +E G + + +ELQ + LE
Sbjct: 709 LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLE 756
Score = 46.8 bits (106), Expect = 2e-04
Identities = 67/321 (20%), Positives = 125/321 (38%), Gaps = 14/321 (4%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+KE T+L +Q+ +++L N + +++ E L+ + E ++ K ++ K
Sbjct: 2194 EKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKL 2253
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
++ + Q Q+ F + ++E E E D + T+ + K + +E+
Sbjct: 2254 GLAIKESDAMSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEE 2311
Query: 301 EVTRLRANERSLR----DAICNKLLLEEQVHQLTSRVEALQPVQLEL-HEAKVKLSSVES 355
+ +R E + D C K EE++ QL +E LQ + + + S+
Sbjct: 2312 KNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE 2371
Query: 356 QLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERD 415
+ +S E AL +E+A LT+E+ +LK ER+
Sbjct: 2372 EADSLKHQLDVVIAEKL-ALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERE 2430
Query: 416 KATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGS 475
K+ + N K L V D+ L E + E G GS
Sbjct: 2431 SVE-KIQSIPENSVNVAIDHLSKDKPELEVVLTEDA----LKSLENQTYFKSFEENGKGS 2485
Query: 476 VALLSARVQQLEKSLQGYRDL 496
+ L R++QLE ++ +DL
Sbjct: 2486 IINLETRLRQLESTVSA-KDL 2505
Score = 46.4 bits (105), Expect = 3e-04
Identities = 79/368 (21%), Positives = 150/368 (40%), Gaps = 42/368 (11%)
Query: 197 KLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ----TSRAEQCTQLKN 252
+L+ + K + +E K +EL + L E L EL K A++ T +
Sbjct: 1877 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1936
Query: 253 QLEKQ-------NFEFQQVTSKLKELEYERDSYKDWQ---TQSKTA---------QKRLC 293
Q++++ E +++L+ELE E+ ++ + ++ K A Q+ L
Sbjct: 1937 QIQEKTDVIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 1996
Query: 294 NMAELEKEVTRLRANERSLRDAICNKL-LLEEQVHQLTSR-VEALQPVQLELHEAKVKLS 351
+L KE ++ +RD + ++ LE V + SR +E Q EL + + +
Sbjct: 1997 ETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQ 2056
Query: 352 SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLK 411
++E QLE ++ RD + + H T EV L
Sbjct: 2057 ALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLA 2115
Query: 412 YERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEE 471
+ T K ++L ++ +LQ+ + +ER+ ++L+ +EL L E+
Sbjct: 2116 NHLKEKTDKCSELLLSKE-------QLQRDI----QERNEEIEKLEFRVRELVQALLVED 2164
Query: 472 GAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVT 531
A+ + LE LQ RD I + K + +L ++ ++REE E +V
Sbjct: 2165 RKHFGAVEAKPELSLEVQLQAERDAIDRKE-----KEITNLEEQLEQFREELENKNEEVQ 2219
Query: 532 KLRTQRDL 539
+L Q ++
Sbjct: 2220 QLHMQLEI 2227
Score = 45.2 bits (102), Expect = 7e-04
Identities = 62/288 (21%), Positives = 130/288 (45%), Gaps = 27/288 (9%)
Query: 95 LKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXX 154
++++L + K + T+L+ +++ + + E++ + K L K + + ++E
Sbjct: 3128 MQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLE 3187
Query: 155 XXXXXXXXKDEFNTAAKEHKDLKA-NW--DKEKTDLHKQIADLKDKLLEANVS---NKDQ 208
+T A EHK + W +KEK L + K++L + S K +
Sbjct: 3188 VKDKTDEVHLLNDTLASEHKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQR 3247
Query: 209 ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE-QCTQLKNQLEKQNFEFQQVTSK 267
++ +++ Q L +Q ++E + Q S + + +L+ L+ Q ++++S
Sbjct: 3248 NLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLQSQKVRIREMSST 3307
Query: 268 LKELEYERDSYKDWQTQSKTAQKR--LCN---MAELEKE--------VTRLRANERSLRD 314
L + ER+ + Q+ T Q R L + + EL+K+ V L E+ D
Sbjct: 3308 L---DRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLD 3364
Query: 315 AICNKLLLEE--QVHQLTSRVE--ALQPVQLELHEAKVKLSSVESQLE 358
++ + +E+ QVH+ T + E A Q ++HE + K+ ++ QLE
Sbjct: 3365 SLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLE 3412
Score = 45.2 bits (102), Expect = 7e-04
Identities = 68/278 (24%), Positives = 123/278 (44%), Gaps = 32/278 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + ++++ ++ L + +H +E+Q E+EKA L +RD+ + D++
Sbjct: 3180 ELEAFRLEVKDKTDEVHLLNDTLASEHKKSRELQWALEKEKAKLGRSEERDKEELEDLK- 3238
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHK-----QIADLKDKLLEANV-- 203
+ N ++ K L N ++K + + Q+++ + + LE V
Sbjct: 3239 ---FSLESQKQRNLQLNLLLEQQKQL-LNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 3294
Query: 204 -SNKDQISEMKKDMD---EL---LQALEG-AQSE----VEMLKKELVKQ-TSRAEQCTQL 250
S K +I EM +D EL LQ+ +G QS E L KEL KQ + + +L
Sbjct: 3295 QSQKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVEL 3354
Query: 251 KNQLEKQNFEFQQVTSKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
N+ EK + Q ++ K+ + R + + Q + QK+ M EL+ +V L+
Sbjct: 3355 LNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK---MHELQSKVEDLQRQL 3411
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAK 347
R + KL LE Q +L ++ Q +LE E +
Sbjct: 3412 EEKRQQV-YKLDLEGQ--RLQGIMQEFQKQELEREEKR 3446
Score = 42.7 bits (96), Expect = 0.004
Identities = 31/110 (28%), Positives = 63/110 (57%), Gaps = 7/110 (6%)
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS--EMKKDMDELLQALEGAQSEVEML 233
+K N ++E L++ I L+ +L AN+ K ++ + ++ D L L+ +E L
Sbjct: 2333 VKRNREEEIEQLNEVIEKLQQEL--ANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLAL 2390
Query: 234 KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQT 283
++++ +T+ E+ T +KN L++ NF+ Q+T +L L+ ER+S + Q+
Sbjct: 2391 EQQV--ETAN-EEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQS 2437
Score = 35.9 bits (79), Expect = 0.43
Identities = 80/438 (18%), Positives = 173/438 (39%), Gaps = 28/438 (6%)
Query: 182 KEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE-VEMLKKELVKQ 240
K++ H+Q + +D LLE K+ + + E ++ E Q + VE KE +++
Sbjct: 267 KQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQE 326
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+ +L + E ++ T +LK+ D + Q + QK + ++
Sbjct: 327 KET------IIEELNTKIIEEEKKTLELKDKLTTADKLLG-ELQEQIVQKNQ-EIKNMKL 378
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQP--VQLELHEAKVKLSSVESQLE 358
E+T + ER + I + E++ + + + VQ E + KL + ++L+
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELD 438
Query: 359 SWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKAT 418
+G + ++ + + + + +
Sbjct: 439 EM------YGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENALRSYSNITVNEDQIKLMN 492
Query: 419 GKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCG-EEGAGSVA 477
+N+L ++ S +L++ L L+ E+ + ++QL+ +EL+ + + ++A
Sbjct: 493 VAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRGQIQRARQTIA 552
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN--EVTRWREEAEGARRDVTK-LR 534
+++ + KSL DL A + S+ L++ EVT ++ + E ++ L
Sbjct: 553 EQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLD 612
Query: 535 TQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQE-EIKKLKVALREGGAQA 593
+ A LER+ Q H E ++ ++LE I+KLK L Q
Sbjct: 613 RMAESQEAELERLSTQLLFSH------EEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQ 666
Query: 594 DPEELQQMRQQLENSRIK 611
+M Q++E + +
Sbjct: 667 IDGLQNEMSQKIETMQFE 684
Score = 35.9 bits (79), Expect = 0.43
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 8/110 (7%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQL---- 250
KDK S D+IS D L E ++E +++ELV+Q +Q T+L
Sbjct: 1555 KDKTFIVRQSIHDEISVSSMDASRQLMLNE---EQLEDMRQELVRQYQEHQQATELLRQA 1611
Query: 251 -KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
Q+E+Q + +Q+ ++K L + ++ +++ + ELE
Sbjct: 1612 HMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELE 1661
Score = 35.9 bits (79), Expect = 0.43
Identities = 79/423 (18%), Positives = 184/423 (43%), Gaps = 43/423 (10%)
Query: 210 SEMKKDMDELLQALEGA-QSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNF-EFQQVTSK 267
+E+ + +EL+ + Q+ VE L + + + +S+ E + +L +++F + Q+ T
Sbjct: 1833 TEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATES 1892
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL-----L 322
LK E R+ + +S+ ++ +++ E + A+E++L + + L
Sbjct: 1893 LKCQEELRERLHE---ESRAREQLAVELSKAEGVIDGY-ADEKTLFERQIQEKTDVIDRL 1948
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGV-ESAGALRDALES 381
E+++ ++R++ L+ Q ++ E + LS + +++ + E+ +++ LE
Sbjct: 1949 EQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEV 2008
Query: 382 ALGXXXXXXXXXXXXXXXXXHLTEEVAT-LKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ E+V+ ++ E++K T +L DL + E + +++K
Sbjct: 2009 QCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT-ELMDLRQQNQALEKQLEKMRK 2067
Query: 441 RL--LLVTRE--RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
L + RE RD ++Q++ E++L V R Q + + +
Sbjct: 2068 FLDEQAIDREHERDVFQQEIQKLEQQLKVV--------------PRFQPISEHQTREVEQ 2113
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHL 556
+A H K E L ++ E +RD+ + + + L + + V
Sbjct: 2114 LANHLKEKTDKCSELLLSK--------EQLQRDIQERNEEIEKLEFRVRELVQALLVEDR 2165
Query: 557 TNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLKRYS 616
+ A EA+ ++S E++ E + + +E E+L+Q R++LEN ++++
Sbjct: 2166 KHFGAVEAKPELSLEVQLQAE---RDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLH 2222
Query: 617 IVL 619
+ L
Sbjct: 2223 MQL 2225
Score = 35.9 bits (79), Expect = 0.43
Identities = 70/309 (22%), Positives = 130/309 (42%), Gaps = 39/309 (12%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQ-HTIRKEMQIL---FEEEKASLIEQ--HKRDERA 144
+ K L+ID+ ++ +LE N + +R++ Q L E+ + L EQ + ER
Sbjct: 2022 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERD 2081
Query: 145 VSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVS 204
V E + + AN KEKTD ++ K++L
Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQE 2141
Query: 205 NKDQISEMKKDMDELLQALE-------GA-------------QSEVEMLKKELVKQTSRA 244
++I +++ + EL+QAL GA Q+E + + ++ + T+
Sbjct: 2142 RNEEIEKLEFRVRELVQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLE 2201
Query: 245 EQCTQLKNQLEKQNFEFQQV-----------TSKLKELEYERDSYKDWQTQSKTAQKRLC 293
EQ Q + +LE +N E QQ+ T++L+ELE E +KD + A K
Sbjct: 2202 EQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESD 2261
Query: 294 NMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
M+ ++ V + +++ L EQV +L +++ ++ + E + +
Sbjct: 2262 AMSTQDQHVL-FGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKV-IEEKNELIRDL 2319
Query: 354 ESQLESWMS 362
E+Q+E MS
Sbjct: 2320 ETQIECLMS 2328
Score = 35.9 bits (79), Expect = 0.43
Identities = 38/181 (20%), Positives = 93/181 (51%), Gaps = 6/181 (3%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD-QISEMKKDMDELLQALEGAQSEVEMLKKELVK 239
+ E+T++ + + L++ L +++S +ISE++ + E+ +L + +VE+ +K +++
Sbjct: 2572 EPERTNI-QNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLE 2630
Query: 240 QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELE 299
+ + + +L EK+ E ++ S +++E + + + + + ++ E
Sbjct: 2631 KEKKLLELQKLLEGNEKKQREKEKKRSP-QDVEVLKTTTELFHSNEESGFFNELEALRAE 2689
Query: 300 KEVTRLR-ANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
T+ A+ + + + +LL++E +TS + L V+ L EAK KLS +E + E
Sbjct: 2690 SVATKAELASYKEKAEKLQEELLVKET--NMTSLQKDLSQVRDHLAEAKEKLSILEKEDE 2747
Query: 359 S 359
+
Sbjct: 2748 T 2748
Score = 33.9 bits (74), Expect = 1.7
Identities = 36/171 (21%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSE-----VEMLKKEL 237
E + +Q+ +KL++ + + Q +++ D+ + ++ALE E +E+ +++
Sbjct: 1986 EAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKN 2045
Query: 238 VKQTSRAEQCTQLKNQLEK-QNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+ +Q L+ QLEK + F +Q + E + + + + Q K +
Sbjct: 2046 TELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISE 2105
Query: 297 ELEKEVTRLRANERSLRDAICNKLLL-EEQVHQ-LTSRVEALQPVQLELHE 345
+EV +L AN + C++LLL +EQ+ + + R E ++ ++ + E
Sbjct: 2106 HQTREVEQL-ANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRE 2155
Score = 32.3 bits (70), Expect = 5.3
Identities = 46/252 (18%), Positives = 107/252 (42%), Gaps = 13/252 (5%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXX 157
D+ A +I++LES+V HT ++ E+E+ + E++ E+ +E
Sbjct: 2592 DISALTLRISELESQVVEMHT-----SLILEKEQVEIAEKNVL-EKEKKLLELQKLLEGN 2645
Query: 158 XXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMD 217
+ E + ++ + LK + ++ + + L +V+ K +++ K+ +
Sbjct: 2646 EKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAE 2705
Query: 218 ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
+L + L ++ + L+K+L + + + + LEK+ + +V K +E
Sbjct: 2706 KLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKE--DETEVQESKKACMFEPLP 2763
Query: 278 YK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEAL 336
K S+T + + ++ A + + C+ + E + Q T ++E +
Sbjct: 2764 IKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKM 2823
Query: 337 QPVQLELHEAKV 348
Q ELH A++
Sbjct: 2824 Q----ELHAAEI 2831
Score = 31.9 bits (69), Expect = 6.9
Identities = 56/216 (25%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 120 RKEMQILF--EEEKASLIEQHKRDER-AVSDMEDXXXXXXXXXXXX-KDEFNTAAKEHKD 175
R Q+LF EEE + L E + + R ++ ++D ++E + + +
Sbjct: 624 RLSTQLLFSHEEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQF 683
Query: 176 LKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLK- 234
K N ++ L +I+ LKD L ++ V++K + EM ++EL Q E+E+L+
Sbjct: 684 EKDNLITKQNQLILEISKLKD-LQQSLVNSKSE--EMTLQINEL-------QKEIEILRQ 733
Query: 235 KELVKQTSRAE-QCTQLKNQ-LEKQNFEFQ-QVTSKLKELEYERDSYKDWQTQSKTAQKR 291
+E K T E Q QLK + LEKQ E + + K +LE E KD + ++ +
Sbjct: 734 EEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKD-EKKTLEDMLK 792
Query: 292 LCNMAELEKEVTRLRANERSLRDAICNK---LLLEE 324
+ E+ + L + + +D++ K +L+EE
Sbjct: 793 IHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE 828
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 50.8 bits (116), Expect = 1e-05
Identities = 96/406 (23%), Positives = 184/406 (45%), Gaps = 44/406 (10%)
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEY 273
K ++ L Q ++ ++ ++ K+ + S EQCT L + EK+ + +Q+ +L+ELE
Sbjct: 134 KTLETLQQRVKRQENLLKRCKETI---QSHKEQCTLLTS--EKEALQ-EQLDERLQELEK 187
Query: 274 ERDSYKDWQTQSKTAQKRLCNMAE-LEKEVTRLRAN-ERSLRDAICNKLLLEEQVHQLTS 331
+D + +T+ T + N+ E LE++ + A +R + + + K EE++ QL S
Sbjct: 188 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK---EEEIAQLRS 244
Query: 332 RVEALQPVQLELHEAKVKLS-SVESQLESWMSAARAHGVESAGALRDALESALGXXXXXX 390
R++ + EL E K K + +LE +S A+ E+ L+ ++ +
Sbjct: 245 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ-KTEEARRKLKAEMDEQIKTIEKTS 303
Query: 391 XXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK-RLLLVTRER 449
EE +L+ E + ++ D+ ++K+ E I +LQK + R+
Sbjct: 304 -------------EEERISLQQELSRVKQEVVDV--MKKSSEEQIAKLQKLHEKELARKE 348
Query: 450 DSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYRDLIAAHDPHAHSKA 508
++L E+E + VAL ++ + L+ S + ++ +A + KA
Sbjct: 349 QELTKKLQTREREFQEQM-------KVALEKSQSEYLKISQEKEQQESLALEELELQKKA 401
Query: 509 -LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQ 567
L N++ ++EAE R + +L + L SL+ Q+K L + AE K
Sbjct: 402 ILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENENQSK--DLAVHLEAEKNKH 456
Query: 568 ISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+KE+ E+ K +L+ EELQ ++QQ + KL+
Sbjct: 457 -NKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLR 501
Score = 46.4 bits (105), Expect = 3e-04
Identities = 54/253 (21%), Positives = 111/253 (43%), Gaps = 16/253 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTI-RKEMQILFEE-EKASLIEQHKRDERAVSDM 148
+ K L ++ K I +L+S + Q + R EM+ L + EK ++Q + +
Sbjct: 1698 QEKELTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELL 1755
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSN 205
E+ + +H DL+ A ++EK L K+I L+ L +
Sbjct: 1756 EENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 1815
Query: 206 KDQISEMKKDMD-ELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQV 264
+ ++ +KK+ D E + ++ Q ++E+ +KQ R E TQL + ++ ++
Sbjct: 1816 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR-EFNTQLAQKEQELEMTIKET 1874
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
+K +E+E E ++ + + L +AE + ++ R + DA + +
Sbjct: 1875 INKAQEVEAEL-----LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA--REEEMTA 1927
Query: 325 QVHQLTSRVEALQ 337
+V L +++E LQ
Sbjct: 1928 KVRDLQTQLEELQ 1940
Score = 45.2 bits (102), Expect = 7e-04
Identities = 89/447 (19%), Positives = 177/447 (39%), Gaps = 38/447 (8%)
Query: 185 TDLHKQIADLKDKLLEANVSNKD---QISEMKKDMDELLQALEGAQSEVEMLKKELVKQ- 240
++L Q+ L ++ N+S + Q+ E + + + +E +E E L+KE Q
Sbjct: 1127 SELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQ 1186
Query: 241 --TSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAE 297
S E C TQLK +L + + +LKE + E S T + +++E
Sbjct: 1187 QAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1246
Query: 298 LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E ++ LR + + C L +QV L+ +V+ L ++ E ++ ++
Sbjct: 1247 KEAAISSLR---KQYDEEKCELL---DQVQDLSFKVDTLSKEKISALE---QVDDWSNKF 1297
Query: 358 ESWMSAARAHGVESAGALRD---ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYE- 413
W A++ + +++ LE + LK E
Sbjct: 1298 SEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEM 1357
Query: 414 ---RDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS-------YRQQLDCYEKEL 463
+ K K ++L T K+Q + I L+ + T E +S Y QQ D KEL
Sbjct: 1358 EDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKEL 1417
Query: 464 TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLR-NEVTRWREE 522
L + G RV++ E+ + + + + +K E N + +EE
Sbjct: 1418 VQKLQHFQELGEEK--DNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1475
Query: 523 AEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKL 582
A D +L ++ A L+R Q K+ + ++ +++ + + + + +L
Sbjct: 1476 ELKALED--RLESESAAKLAELKRKAEQ-KIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1532
Query: 583 KVALREGGAQADPEELQQMRQQLENSR 609
L+E + + L++ + +E+S+
Sbjct: 1533 NTKLQE--REREVHILEEKLKSVESSQ 1557
Score = 42.7 bits (96), Expect = 0.004
Identities = 94/530 (17%), Positives = 209/530 (39%), Gaps = 50/530 (9%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
+L+ +L K Q K++ + + +K +++ S+I++H E ++ E
Sbjct: 557 KLEEELSVLKDQTDKMKQELEAKMDEQKNHH---QQQVDSIIKEH---EVSIQRTEKALK 610
Query: 154 XXXXXXXXXKDEFNTAAKEHK----DLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
E + KEH+ +L+A+ + + +L + A L D + +Q
Sbjct: 611 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQT 669
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKELVK-QTSRAEQCTQLK----------NQLEKQN 258
++ + +L Q L ++E +L K++ + + + + CT+L QLEKQN
Sbjct: 670 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 729
Query: 259 FEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN 318
E +Q L ++ YE + Q +T Q + E E + ++R ++ + +
Sbjct: 730 SEMEQKVKSLTQV-YESKLEDGNKEQEQTKQ----ILVEKENMILQMREGQKKEIEILTQ 784
Query: 319 KL-LLEEQVHQLTSRVEA-LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALR 376
KL E+ +H L E + + ++ + K K ++ L+ + A +
Sbjct: 785 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELE--N 842
Query: 377 DALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIH 436
ALE + +++ V+ L+ + + ++ LT V + + + +
Sbjct: 843 TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE---QIESLTEVHRRELNDVI 899
Query: 437 RLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDL 496
+ ++ L E ++ EKE V E + L +++ K + ++
Sbjct: 900 SIWEKKLNQQAEELQEIHEIQLQEKEQEVA----ELKQKILLFGCEKEEMNKEITWLKEE 955
Query: 497 IAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL-----ERIGPQT 551
D L L+ ++ + +D TKL+ + L L E Q
Sbjct: 956 GVKQD-----TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQE 1010
Query: 552 KVLHLTNNPAAEAQK--QISKELEAAQEEIKKLKVALREGGAQADPEELQ 599
+++ L + +K +++ +L+ EE + LK + + + + L+
Sbjct: 1011 QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1060
Score = 42.3 bits (95), Expect = 0.005
Identities = 56/251 (22%), Positives = 114/251 (45%), Gaps = 19/251 (7%)
Query: 128 EEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHK--DLKAN---WDK 182
+E+ SL E H+R+ V + + E KE + +LK +
Sbjct: 881 KEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 940
Query: 183 EKTDLHKQIADLKDKLLEANVSN---KDQISEMKKDMDELLQALEGAQSEVEMLK----K 235
EK +++K+I LK++ ++ + + ++Q+ + ++ L Q ++ +E L+ K
Sbjct: 941 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1000
Query: 236 ELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS-KTAQKRLCN 294
L + T EQ +LK E+ + ++TSKLK + E S K +S K+ + +
Sbjct: 1001 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1060
Query: 295 MAELEKEVT-RLR---ANERSLRDAICNKL--LLEEQVHQLTSRVEALQPVQLELHEAKV 348
+L +E+ +L +L +A N+L + + + + SR+ Q ++ EA +
Sbjct: 1061 FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1120
Query: 349 KLSSVESQLES 359
+ S+LE+
Sbjct: 1121 IKTCTVSELEA 1131
Score = 39.1 bits (87), Expect = 0.046
Identities = 49/257 (19%), Positives = 106/257 (41%), Gaps = 20/257 (7%)
Query: 93 KRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXX 152
K L+I L + + + ++N + F+ K + + + E+ S++E
Sbjct: 1316 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETEL 1375
Query: 153 XXXXXXXXXXKDEFNTAAKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+D E + L N++++K HK++ E +++
Sbjct: 1376 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRV 1435
Query: 210 SEMKKDMDELLQALEGAQSEVEMLKKEL----VKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
E ++ + L + ++E+E KKEL + S+ E+ L+++LE ++
Sbjct: 1436 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES------A 1489
Query: 266 SKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ 325
+KL EL+ + + + +K+L + E EKE + E L + E +
Sbjct: 1490 AKLAELKRKAEQ------KIAAIKKQLLSQME-EKEEQYKKGTESHLSELNTKLQERERE 1542
Query: 326 VHQLTSRVEALQPVQLE 342
VH L ++++++ Q E
Sbjct: 1543 VHILEEKLKSVESSQSE 1559
Score = 38.3 bits (85), Expect = 0.080
Identities = 55/264 (20%), Positives = 118/264 (44%), Gaps = 18/264 (6%)
Query: 107 TKLESRVNHQHTI-RKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
T+LES + Q + +E+Q+L ++ + E K E+ + E +E
Sbjct: 469 TELESLKHQQDALWAEELQVLKQQYQT---EMEKLREKCEQEKETLLKDKEIIFQAHIEE 525
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
N E D+ + + ++ + KL E KDQ +MK++++ + +
Sbjct: 526 MNEKTLEKLDVNQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKN 585
Query: 226 -AQSEVEMLKKE---LVKQTSRA--EQCTQLKNQLEKQNFEFQQVTSKLKELE--YERDS 277
Q +V+ + KE +++T +A +Q QL+ L++++ ++ + ++ LE +R
Sbjct: 586 HHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSE 645
Query: 278 YKDWQTQSKTAQKRLCNMAELEKEVT---RLRANERSLRDAICNKLLLEEQVHQLTSRVE 334
+ Q +K + A E+ +L ++ L D ++LL +QV ++ ++
Sbjct: 646 GELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQ-- 703
Query: 335 ALQPVQLELHEAKVKLSSVESQLE 358
+ V EL K+++ + QLE
Sbjct: 704 -KKDVCTELDAHKIQVQDLMQQLE 726
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/287 (19%), Positives = 134/287 (46%), Gaps = 15/287 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDM 148
+ KR K L A+ + L++ + I + L E E A+ ++ K E + D+
Sbjct: 1670 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1729
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN-----V 203
+++ + +E +++ ++++ D+++ + K + +A+ +
Sbjct: 1730 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1789
Query: 204 SN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT--SRAE-QCTQLKNQLEKQNF 259
++ + Q+ E K+ EL + L+ QS+VE L++ +V ++ SR E + +L+ +LE +
Sbjct: 1790 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1849
Query: 260 E---FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
+ + + S+LKE + +D + ++ +K + + T+ E + ++A
Sbjct: 1850 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1909
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
++ E ++ L S A Q +Q +L A ++ +++ +E M +
Sbjct: 1910 ASRKKHELEM-DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMES 1955
Score = 44.0 bits (99), Expect = 0.002
Identities = 93/436 (21%), Positives = 169/436 (38%), Gaps = 38/436 (8%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXX 157
L K Q+ LE++V Q E ++ + ++EQ K R E + M
Sbjct: 1550 LAKVKKQLRDLEAKVKDQ-----EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEME 1604
Query: 158 XXXXXKDEFNTAA-KEHKDLKANWDKEKTDLHKQIAD---LKDKL--LEANVSNKDQISE 211
+E + K+ K ++ ++E D K + + L+ KL L V+ +D SE
Sbjct: 1605 SRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE 1664
Query: 212 --MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++KD+ L AQ ++ LK + + QLKNQLE+ F K
Sbjct: 1665 KRLRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESEFTCAAAVKARK 1720
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ- 325
+E E + D ++KTA + + + EK + R E D N+L+ + +
Sbjct: 1721 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL-EEDQED--MNELMKKHKA 1777
Query: 326 -VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
V Q + + + +Q +L EA + ++ +L++ S + +E + + +
Sbjct: 1778 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS--QVEFLEQSMVDKSLVSRQEA 1835
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
L + LK +K T + + ++ RLQ++L
Sbjct: 1836 KIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL-- 1893
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYR---DLIAAH 500
RD+ + + KE + E + L A Q L+ L+ ++ DL AA
Sbjct: 1894 ----RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAI 1949
Query: 501 DPHAHSKALESLRNEV 516
+ S E L N +
Sbjct: 1950 EDEMESDENEDLINSL 1965
Score = 37.5 bits (83), Expect = 0.14
Identities = 67/365 (18%), Positives = 159/365 (43%), Gaps = 22/365 (6%)
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANE 309
+ Q+ ++ E QQ+ SKL++ E ER+ + + S + R+ + +EL E +
Sbjct: 1266 EEQIRNKDEEIQQLRSKLEKAEKERN---ELRLNSDRLESRISELTSELTDERNTGESAS 1322
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG- 368
+ L +L E+++ +L ++ +AL+ Q+E+ E +V +E++L + AA +G
Sbjct: 1323 QLLDAETAERLRAEKEMKELQTQYDALKK-QMEVMEMEV----MEARL---IRAAEINGE 1374
Query: 369 VESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
V+ A E L +++ + + + +L DL
Sbjct: 1375 VDDDDA---GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADS 1431
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYE---KELTVTLCGEEGAGSVALLSARVQQ 485
+ + + +L+K+ +T E + L+ + EL + S A A+ ++
Sbjct: 1432 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1491
Query: 486 LEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
L++ LQ +D++ A + + + LE ++ + ++ ++ + +Q ASL
Sbjct: 1492 LQREKLQREKDMLLA-EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL 1550
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
++ Q + L E + + ++ ++ +L++ + E Q +E++ ++
Sbjct: 1551 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM-ERMRQTHSKEMESRDEE 1609
Query: 605 LENSR 609
+E +R
Sbjct: 1610 VEEAR 1614
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/199 (19%), Positives = 101/199 (50%), Gaps = 4/199 (2%)
Query: 186 DLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAE 245
DL +Q+ ++L EA +S K++I++ ++D + AL+ +S + + L+++ ++++
Sbjct: 173 DLDRQLKKTTEELNEA-LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD 231
Query: 246 QCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSKTAQKRLCNMAELEKEVTR 304
+ +++ + Q +L+E + ++ KD ++ + + +K + + + E+T
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 305 LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWM--S 362
L +SL+D I ++V +L +VE+ + +L + + ++ +E + +M +
Sbjct: 292 LADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNT 351
Query: 363 AARAHGVESAGALRDALES 381
+ + A A R LE+
Sbjct: 352 VSLEEELRKANAARSQLET 370
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 50.8 bits (116), Expect = 1e-05
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 29/402 (7%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ +++ DMD ++ Q V+ K+EL K + ++ L + K+ +FQ +K
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L++ E E+ S Q + QK L + E+EV ++R + L NK + EQ+H
Sbjct: 284 LQQ-ENEQHSLVCEQLSQENQQKAL-ELKAKEEEVHQMRLDIGKL-----NK--IREQIH 334
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
+ E Q ++E H+ +K V LE + A++ + A R A++ L
Sbjct: 335 KKLHHTED-QKAEVEQHKETLKNQIV--GLEREVEASK----KQAELDRKAMDELLRERD 387
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
T+ V + + G++ + + Q +I L+K
Sbjct: 388 ILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEK------- 440
Query: 448 ERDSY-RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHA 504
ERD Y Q D +K L + + ++ + E L+ ++L A D +
Sbjct: 441 ERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNL 500
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG-PQTKVLHLTNNPAAE 563
+SK L ++E+T + + + V +L+ ++L ++ Q ++ AE
Sbjct: 501 YSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAE 560
Query: 564 AQKQISKELEAAQ--EEIKKLKVALREGGAQADPEELQQMRQ 603
QK + LE E+ + + L A+AD E L+Q ++
Sbjct: 561 LQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKE 602
Score = 38.7 bits (86), Expect = 0.060
Identities = 66/356 (18%), Positives = 146/356 (41%), Gaps = 39/356 (10%)
Query: 187 LHKQIADLKDKLLEANVSNKDQ---ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
L ++I +L + + + + DQ I ++ + +E+ + + SEV L++ L + T +
Sbjct: 123 LKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQ 182
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVT 303
++ + K + E +FQQ + Q + A + +LEKE+
Sbjct: 183 QQETERSKEEAEHAISQFQQ----------------EIQQRQNEASREFRKKEKLEKELK 226
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW-MS 362
+++A+ S + I L++ V + E LQ ++ +L E K+ +LE + M
Sbjct: 227 QIQADMDSRQTEI---KALQQYVQK---SKEELQKLEQQLKEQKILNERAAKELEQFQMR 280
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A+ +L E + ++ L R++ KL+
Sbjct: 281 NAKLQQENEQHSL--VCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH 338
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
+ E L+ +++ + RE ++ ++Q + K + L + +L+
Sbjct: 339 HTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD------ILNKN 392
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
+ + + Q DL+ H+ +A +L E+ +++EA+ R+ + L +RD
Sbjct: 393 MLKAVNATQKQTDLVKLHE-----QAKRNLEGEIQNYKDEAQKQRKIIFHLEKERD 443
Score = 34.7 bits (76), Expect = 0.98
Identities = 53/283 (18%), Positives = 123/283 (43%), Gaps = 27/283 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K+++ D+ + + +I L+ V ++E+Q L ++ K EQ +ERA ++E
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKS---KEELQKLEQQLK----EQKILNERAAKELEQ 276
Query: 151 XXXXXXXXXXXXKDEF---NTAAKEHKDLKANWDKEKTDLHKQIADL------KDKLLEA 201
+ ++E++ ++ ++H+ D+ ++++ +
Sbjct: 277 FQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKK 336
Query: 202 NVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
+DQ +E+++ + L + G + EVE KK+ ++ + ++ L K +
Sbjct: 337 LHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKA 396
Query: 262 QQVTSKLKEL-----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
T K +L + +R+ + Q AQK+ + LEKE R N+ S +
Sbjct: 397 VNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRY-INQAS---DL 452
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
K+L+ + + R + + ++ E+++KL ++ E+
Sbjct: 453 TQKVLM--NMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEA 493
>BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1107
Score = 50.8 bits (116), Expect = 1e-05
Identities = 102/500 (20%), Positives = 217/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 272 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 330
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 331 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 385
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 386 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 435
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 436 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 495
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L +A +A+L+ +++
Sbjct: 496 QLQQELENLKEV-----LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 550
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 551 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 598
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 599 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 658
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E+ ++ +L+E
Sbjct: 659 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 718
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 719 VLAFQTMEEEKEKEQRALEN 738
Score = 44.4 bits (100), Expect = 0.001
Identities = 55/289 (19%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 591 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 650
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 651 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 710
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 711 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 770
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 771 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 826
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ + L LHE +S++ +LE
Sbjct: 827 RQSKEHICRITDLQEELRHREHHISELDKEVQHLHE---NISALTKELE 872
Score = 39.9 bits (89), Expect = 0.026
Identities = 61/287 (21%), Positives = 125/287 (43%), Gaps = 34/287 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 403 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 462
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKD--Q 208
K + + + +KD K N +++K L +++ +LK+ L + N +N++
Sbjct: 463 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGH 521
Query: 209 ISEMKKDMDELLQALEG----AQSEVEMLKKEL-VKQTSRAEQCTQLKN---QLEKQNFE 260
+ +M + ++ L + EG Q E L+ EL + + S E L N +LE++ +
Sbjct: 522 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ 581
Query: 261 FQQVTSKLKELE------YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL-- 312
++ + +KE E D W + +L L+ E + A + L
Sbjct: 582 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQL 641
Query: 313 --RDAICNKLLLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQ 356
R+ + +++V L +++ L Q ++++L +++ L +++Q
Sbjct: 642 KDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQ 688
Score = 31.9 bits (69), Expect = 6.9
Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 835 RITDLQEELRH----REHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 890
Query: 250 LKNQ-LEKQ-NFEFQQVTS-KLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
L Q L K+ E +T+ L+E R + K L ++ E+E++
Sbjct: 891 LHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMR 950
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
+ ++ K +L E+ + +E + QLEL + + V
Sbjct: 951 ESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKV 998
>BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein.
Length = 622
Score = 50.8 bits (116), Expect = 1e-05
Identities = 83/377 (22%), Positives = 162/377 (42%), Gaps = 28/377 (7%)
Query: 223 LEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQ 282
L A++++ L++EL ++T EQ K +LE+ E +++ + L + S + ++
Sbjct: 253 LADAKAKIRRLRQELEEKT---EQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR 309
Query: 283 TQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE--QVHQLTSRVEALQPVQ 340
+ ++++ + +LE EV+R + ER L D K +EE + +Q+ + + Q
Sbjct: 310 DELDALREKVVRVDKLESEVSRYK--ER-LHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Query: 341 LELHEAKV-KLSSVESQLESWMSAARAHGVESAGAL-RDALESALGXXXXXXXXXXXXXX 398
LE A+ KL +E E+ A+ H +E + R +E +
Sbjct: 367 LEGTRARSDKLHELEK--ENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 399 XXXHLTEEVATLKYERDKATGKLNDL-TTVRKNQESLIHRLQKRLLLVTRERDSYRQQLD 457
HL E+ + + + L V + S + +L+ +T+ + R +D
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 458 CYE----KELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI--AAHDPHAHSKALES 511
E K L + + + V +L + Q ++SLQ ++L + K +E+
Sbjct: 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544
Query: 512 LRNEVTR----WREEAEGARRDVTKLRTQRDL-LTASLERIGPQTKVLHLTNNPAAEAQK 566
LR R +E E + V+ LR + + A ++ I + K+LH E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH---ESIKETSS 601
Query: 567 QISKELEAAQEEIKKLK 583
++SK +E + +IKK K
Sbjct: 602 KLSK-IEFEKRQIKKKK 617
Score = 33.9 bits (74), Expect = 1.7
Identities = 40/178 (22%), Positives = 78/178 (43%), Gaps = 9/178 (5%)
Query: 187 LHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ 246
L +++ K++L + K ++ E+K+D LL+ + ++E + K ++
Sbjct: 325 LESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Query: 247 CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
QLK +L E K++EL E + + Q QS L + ++ +
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Query: 306 RANERSL----RDAICNKLL-LEEQVHQLTSRVEALQPV--QLELHEAKVKLSSVESQ 356
A ++SL + ++LL LE + LT VE L+ +E + +K+ E+Q
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQ 501
Score = 33.5 bits (73), Expect = 2.3
Identities = 31/169 (18%), Positives = 81/169 (47%), Gaps = 15/169 (8%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQ 240
+ E L K + +L+ + ++ N +I +M+K+ L +VE+L+ E+V++
Sbjct: 466 EMENQSLTKTVEELRTTV-DSVEGNASKILKMEKENQRL-------SKKVEILENEIVQE 517
Query: 241 TSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEK 300
+ C L L K+ + ++ L+E ER K + +++ + + ++ +
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRE-NSER-QIKILEQENEHLNQTVSSL----R 571
Query: 301 EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVK 349
+ +++ A R ++D +L E + + +S++ ++ + ++ + K K
Sbjct: 572 QRSQISAEAR-VKDIEKENKILHESIKETSSKLSKIEFEKRQIKKKKKK 619
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/287 (19%), Positives = 134/287 (46%), Gaps = 15/287 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDM 148
+ KR K L A+ + L++ + I + L E E A+ ++ K E + D+
Sbjct: 1620 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1679
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN-----V 203
+++ + +E +++ ++++ D+++ + K + +A+ +
Sbjct: 1680 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1739
Query: 204 SN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT--SRAE-QCTQLKNQLEKQNF 259
++ + Q+ E K+ EL + L+ QS+VE L++ +V ++ SR E + +L+ +LE +
Sbjct: 1740 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1799
Query: 260 E---FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
+ + + S+LKE + +D + ++ +K + + T+ E + ++A
Sbjct: 1800 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1859
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
++ E ++ L S A Q +Q +L A ++ +++ +E M +
Sbjct: 1860 ASRKKHELEM-DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMES 1905
Score = 44.0 bits (99), Expect = 0.002
Identities = 81/399 (20%), Positives = 153/399 (38%), Gaps = 30/399 (7%)
Query: 128 EEEKASLIEQHKRD-ERAVSDMEDXXXXXXXXXXXXKD--EFNTAAKEHKDLKANWDKEK 184
+E + +++ RD E V D E+ + + +E + K +EK
Sbjct: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREK 1592
Query: 185 TDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA 244
+L ++A L D++ N + + ++KD+ L AQ ++ LK +
Sbjct: 1593 RELEGKLATLSDQV---NRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSK---- 1645
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK---DWQTQSKTAQKRLCNMAELEKE 301
+ QLKNQLE+ F K +E E + D ++KTA + + + EK
Sbjct: 1646 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1705
Query: 302 VTRLRANERSLRDAICNKLLLEEQ--VHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
+ R E D N+L+ + + V Q + + + +Q +L EA + ++ +L++
Sbjct: 1706 EIQNRL-EEDQED--MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQA 1762
Query: 360 WMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATG 419
S + +E + + + L + LK +K T
Sbjct: 1763 LQS--QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTE 1820
Query: 420 KLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALL 479
+ + ++ RLQ++L RD+ + + KE + E + L
Sbjct: 1821 ERDQRIAAENREKEQNKRLQRQL------RDTKEEMGELARKEAEASRKKHELEMDLESL 1874
Query: 480 SARVQQLEKSLQ-GYR---DLIAAHDPHAHSKALESLRN 514
A Q L+ L+ ++ DL AA + S E L N
Sbjct: 1875 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLIN 1913
Score = 38.3 bits (85), Expect = 0.080
Identities = 69/362 (19%), Positives = 160/362 (44%), Gaps = 24/362 (6%)
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANE 309
+ Q+ ++ E QQ+ SKL++ E ER+ + + S + R+ + +EL E +
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERN---ELRLNSDRLESRISELTSELTDERNTGESAS 1309
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG- 368
+ L +L E+++ +L ++ +AL+ Q+E+ E +V +E++L + AA +G
Sbjct: 1310 QLLDAETAERLRAEKEMKELQTQYDALKK-QMEVMEMEV----MEARL---IRAAEINGE 1361
Query: 369 VESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
V+ A E L +++ + + + +L DL
Sbjct: 1362 VDDDDA---GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADS 1418
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYE---KELTVTLCGEEGAGSVALLSARVQQ 485
+ + + +L+K+ +T E + L+ + EL + S A A+ ++
Sbjct: 1419 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1478
Query: 486 LEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
L++ LQ +D++ A + + + LE ++ + ++ ++ + +Q ASL
Sbjct: 1479 LQREKLQREKDMLLA-EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL 1537
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
++ Q + L E + + ++ E++K+++V L E D +++ + +++
Sbjct: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGTIQML-EQLKQMEVQLEE--EYEDKQKVLREKRE 1594
Query: 605 LE 606
LE
Sbjct: 1595 LE 1596
Score = 35.5 bits (78), Expect = 0.56
Identities = 96/505 (19%), Positives = 202/505 (40%), Gaps = 48/505 (9%)
Query: 96 KIDLIAAKAQITKL--ESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXX 153
K + A+ Q TKL E + H + K+ Q F+ E + E+ +R++ ++
Sbjct: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKK-QRRFDSELSQAHEEAQREKLQREKLQREKD 1489
Query: 154 XXXXXXXXXKDEFNTAAKEHKDLK-ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEM 212
K + E KD+ A + ++ L ++ D+ + + S ++++
Sbjct: 1490 MLLAEAFSLKQQL-----EEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS----LAKV 1540
Query: 213 KKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL---K 269
KK + +L ++ + E++ E EQ Q++ QLE+ E++ L +
Sbjct: 1541 KKQLRDLEAKVKDQEEELD----EQAGTIQMLEQLKQMEVQLEE---EYEDKQKVLREKR 1593
Query: 270 ELE------YERDSYKDWQTQS---KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
ELE ++ + +D++++ K ++ +A+ + + L+ + S R+ K
Sbjct: 1594 ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1653
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV---ESQLESWMSAARAHGVESAGALRD 377
LEE + V+A + +++E+ + +++ + ++ LE +S + E L +
Sbjct: 1654 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1713
Query: 378 ALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR 437
E + + A L+ E +K +L + ++Q + +
Sbjct: 1714 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE-EANKEKQELQEKLQALQSQVEFLEQ 1772
Query: 438 LQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLI 497
LV+R+ R+ E E T E +L S + +EK + I
Sbjct: 1773 SMVDKSLVSRQEAKIRELETRLEFERTQVKRLE------SLASRLKENMEKLTEERDQRI 1826
Query: 498 AAHDPHAHSKALESLRNEVTRWREE-AEGARRDVTKLRTQRDLL--TASLERIGPQTKV- 553
AA + + L+ ++ +EE E AR++ R + +L SLE +
Sbjct: 1827 AAENREKEQN--KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1884
Query: 554 LHLTNNPAAEAQKQISKELEAAQEE 578
L L + Q I E+E+ + E
Sbjct: 1885 LKLAFKRIGDLQAAIEDEMESDENE 1909
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 50.8 bits (116), Expect = 1e-05
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 29/402 (7%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ +++ DMD ++ Q V+ K+EL K + ++ L + K+ +FQ +K
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L++ E E+ S Q + QK L + E+EV ++R + L NK + EQ+H
Sbjct: 284 LQQ-ENEQHSLVCEQLSQENQQKAL-ELKAKEEEVHQMRLDIGKL-----NK--IREQIH 334
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
+ E Q ++E H+ +K V LE + A++ + A R A++ L
Sbjct: 335 KKLHHTED-QKAEVEQHKETLKNQIV--GLEREVEASK----KQAELDRKAMDELLRERD 387
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
T+ V + + G++ + + Q +I L+K
Sbjct: 388 ILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEK------- 440
Query: 448 ERDSY-RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHA 504
ERD Y Q D +K L + + ++ + E L+ ++L A D +
Sbjct: 441 ERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNL 500
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG-PQTKVLHLTNNPAAE 563
+SK L ++E+T + + + V +L+ ++L ++ Q ++ AE
Sbjct: 501 YSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAE 560
Query: 564 AQKQISKELEAAQ--EEIKKLKVALREGGAQADPEELQQMRQ 603
QK + LE E+ + + L A+AD E L+Q ++
Sbjct: 561 LQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKE 602
Score = 38.7 bits (86), Expect = 0.060
Identities = 66/356 (18%), Positives = 146/356 (41%), Gaps = 39/356 (10%)
Query: 187 LHKQIADLKDKLLEANVSNKDQ---ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
L ++I +L + + + + DQ I ++ + +E+ + + SEV L++ L + T +
Sbjct: 123 LKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQ 182
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVT 303
++ + K + E +FQQ + Q + A + +LEKE+
Sbjct: 183 QQETERSKEEAEHAISQFQQ----------------EIQQRQNEASREFRKKEKLEKELK 226
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW-MS 362
+++A+ S + I L++ V + E LQ ++ +L E K+ +LE + M
Sbjct: 227 QIQADMDSRQTEI---KALQQYVQK---SKEELQKLEQQLKEQKILNERAAKELEQFQMR 280
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A+ +L E + ++ L R++ KL+
Sbjct: 281 NAKLQQENEQHSL--VCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH 338
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
+ E L+ +++ + RE ++ ++Q + K + L + +L+
Sbjct: 339 HTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD------ILNKN 392
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
+ + + Q DL+ H+ +A +L E+ +++EA+ R+ + L +RD
Sbjct: 393 MLKAVNATQKQTDLVKLHE-----QAKRNLEGEIQNYKDEAQKQRKIIFHLEKERD 443
Score = 34.7 bits (76), Expect = 0.98
Identities = 53/283 (18%), Positives = 123/283 (43%), Gaps = 27/283 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K+++ D+ + + +I L+ V ++E+Q L ++ K EQ +ERA ++E
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKS---KEELQKLEQQLK----EQKILNERAAKELEQ 276
Query: 151 XXXXXXXXXXXXKDEF---NTAAKEHKDLKANWDKEKTDLHKQIADL------KDKLLEA 201
+ ++E++ ++ ++H+ D+ ++++ +
Sbjct: 277 FQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKK 336
Query: 202 NVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
+DQ +E+++ + L + G + EVE KK+ ++ + ++ L K +
Sbjct: 337 LHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKA 396
Query: 262 QQVTSKLKEL-----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
T K +L + +R+ + Q AQK+ + LEKE R N+ S +
Sbjct: 397 VNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRY-INQAS---DL 452
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
K+L+ + + R + + ++ E+++KL ++ E+
Sbjct: 453 TQKVLM--NMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEA 493
>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
Length = 1006
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/296 (23%), Positives = 132/296 (44%), Gaps = 21/296 (7%)
Query: 91 ETKRLKIDLIAAKAQIT-KLESRVNHQHTIRKEMQILFEEEKASL-IEQHKRDE--RAVS 146
+T R++++L KA++ KL + +R+ Q E +ASL E R+E R
Sbjct: 629 KTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKK 688
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
ME + A + ++A +E+ ++ L +L E + +
Sbjct: 689 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEE-QRLAAELHEQAQALE 747
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRA----EQCTQLKNQLEKQNFEFQ 262
+ S + +++EL ALE + + ++EL++ T R Q T L NQ +K +
Sbjct: 748 RRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLA 807
Query: 263 QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA-ELEKEVTRLRANERSLRDAICNKLL 321
Q++ +++E ER ++ + ++K A MA EL+KE ER K
Sbjct: 808 QLSGEVEEAAQER---REAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-------KKT 857
Query: 322 LEEQVHQLTSRVEALQPVQLELHEAKV-KLSSVESQLESWMSAARAHGVESAGALR 376
LE+ V +L +R+E + L + +V KL + +LE+ + A + E+ +R
Sbjct: 858 LEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVR 913
Score = 50.0 bits (114), Expect = 2e-05
Identities = 109/485 (22%), Positives = 191/485 (39%), Gaps = 34/485 (7%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDEL 219
+DE K+ DL+ A +KEK ++ +L +++ + S E K +
Sbjct: 16 EDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAH 75
Query: 220 LQALEGAQSE---VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYER 275
QAL Q+E V L K ++ + E Q +K + ++ KL+ +L+ +
Sbjct: 76 QQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQ 135
Query: 276 DSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLL--LEEQVHQLTSRV 333
+S D Q K + + E LR + L A K + L+ + +L +
Sbjct: 136 ESVAD-AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEEL 194
Query: 334 EALQP----VQLELHEAKVKLSSVESQLE--SWMSAARAHGVE----SAGALRDAL-ESA 382
EA + V+ + EA +L + +LE SA + G G LR L E+A
Sbjct: 195 EAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAA 254
Query: 383 LGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRL 442
L L E+V +L+ R K + ++L + + + L +
Sbjct: 255 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 314
Query: 443 LLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSV---ALLSARVQQLEKSLQGYRDLIA- 498
+ +Y QL E ++ V + A + L +L + L+ LI+
Sbjct: 315 ASAEKLCRTYEDQLS--EAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 372
Query: 499 -AHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTAS-LERIGPQTKVLHL 556
+ +++LE LR ++ + V LR DLL E Q ++ L
Sbjct: 373 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 432
Query: 557 TNNPAAEAQKQISK-ELEAAQ--EEIK--KLKVALREGGAQADPEELQQMRQQLENSRIK 611
+ AE + SK E +A Q EE++ K K+ALR A+ E LE ++++
Sbjct: 433 LSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLR 492
Query: 612 LKRYS 616
L+ S
Sbjct: 493 LQTES 497
Score = 50.0 bits (114), Expect = 2e-05
Identities = 85/469 (18%), Positives = 182/469 (38%), Gaps = 31/469 (6%)
Query: 108 KLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFN 167
+++ ++ +E++ E E+A+ K+ A ++E+ +
Sbjct: 175 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 234
Query: 168 TAAKEHKDL-KANWDKEKTDLHKQ--IADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
K +L + + E+ L + +A L+ K E +Q+ +++ +L +
Sbjct: 235 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 294
Query: 225 GAQSEVEMLK---KELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
+ EV+ L + L + + AE+ C ++QL + + +++ +L + +R +
Sbjct: 295 ELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQT 354
Query: 281 WQTQ-SKTAQKRLCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
+ S+ +++ C +++L + L R L + K L V L +
Sbjct: 355 ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDL 414
Query: 336 LQPVQLELHEAKVKL----SSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXX 391
L+ E EA+ +L S +++ W S A ++ L +A +
Sbjct: 415 LREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEE 474
Query: 392 XXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDS 451
L + L+ E + T +L T+ + L++ L R+ +
Sbjct: 475 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 534
Query: 452 YRQQLDCYEKE---LTVTLCG-----EEGAGSVALLSARVQQLEKSLQGYRDLIAA---- 499
+++L+ ++E L L EE ++ L + L++ + D ++
Sbjct: 535 MQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKS 594
Query: 500 -HDPHAHSKALESLRNEVTRWREEAEGA-RRDVTK-LRTQRDLLTASLE 545
+ KALE ++E+ EEAEGA + TK LR Q +L E
Sbjct: 595 IQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 643
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/287 (19%), Positives = 134/287 (46%), Gaps = 15/287 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDM 148
+ KR K L A+ + L++ + I + L E E A+ ++ K E + D+
Sbjct: 1199 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1258
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN-----V 203
+++ + +E +++ ++++ D+++ + K + +A+ +
Sbjct: 1259 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1318
Query: 204 SN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT--SRAE-QCTQLKNQLEKQNF 259
++ + Q+ E K+ EL + L+ QS+VE L++ +V ++ SR E + +L+ +LE +
Sbjct: 1319 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1378
Query: 260 E---FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
+ + + S+LKE + +D + ++ +K + + T+ E + ++A
Sbjct: 1379 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1438
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
++ E ++ L S A Q +Q +L A ++ +++ +E M +
Sbjct: 1439 ASRKKHELEM-DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMES 1484
Score = 43.6 bits (98), Expect = 0.002
Identities = 93/434 (21%), Positives = 168/434 (38%), Gaps = 38/434 (8%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXX 157
L K Q+ LE++V Q E ++ + ++EQ K R E + M
Sbjct: 1079 LAKVKKQLRDLEAKVKDQ-----EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEME 1133
Query: 158 XXXXXKDEFNTAA-KEHKDLKANWDKEKTDLHKQIAD---LKDKL--LEANVSNKDQISE 211
+E + K+ K ++ ++E D K + + L+ KL L V+ +D SE
Sbjct: 1134 SRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE 1193
Query: 212 --MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++KD+ L AQ ++ LK + + QLKNQLE+ F K
Sbjct: 1194 KRLRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESEFTCAAAVKARK 1249
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ- 325
+E E + D ++KTA + + + EK + R E D N+L+ + +
Sbjct: 1250 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL-EEDQED--MNELMKKHKA 1306
Query: 326 -VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
V Q + + + +Q +L EA + ++ +L++ S + +E + + +
Sbjct: 1307 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS--QVEFLEQSMVDKSLVSRQEA 1364
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
L + LK +K T + + ++ RLQ++L
Sbjct: 1365 KIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL-- 1422
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYR---DLIAAH 500
RD+ + + KE + E + L A Q L+ L+ ++ DL AA
Sbjct: 1423 ----RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAI 1478
Query: 501 DPHAHSKALESLRN 514
+ S E L N
Sbjct: 1479 EDEMESDENEDLIN 1492
Score = 37.5 bits (83), Expect = 0.14
Identities = 67/365 (18%), Positives = 159/365 (43%), Gaps = 22/365 (6%)
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANE 309
+ Q+ ++ E QQ+ SKL++ E ER+ + + S + R+ + +EL E +
Sbjct: 795 EEQIRNKDEEIQQLRSKLEKAEKERN---ELRLNSDRLESRISELTSELTDERNTGESAS 851
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG- 368
+ L +L E+++ +L ++ +AL+ Q+E+ E +V +E++L + AA +G
Sbjct: 852 QLLDAETAERLRAEKEMKELQTQYDALKK-QMEVMEMEV----MEARL---IRAAEINGE 903
Query: 369 VESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
V+ A E L +++ + + + +L DL
Sbjct: 904 VDDDDA---GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADS 960
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYE---KELTVTLCGEEGAGSVALLSARVQQ 485
+ + + +L+K+ +T E + L+ + EL + S A A+ ++
Sbjct: 961 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1020
Query: 486 LEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
L++ LQ +D++ A + + + LE ++ + ++ ++ + +Q ASL
Sbjct: 1021 LQREKLQREKDMLLA-EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL 1079
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
++ Q + L E + + ++ ++ +L++ + E Q +E++ ++
Sbjct: 1080 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM-ERMRQTHSKEMESRDEE 1138
Query: 605 LENSR 609
+E +R
Sbjct: 1139 VEEAR 1143
>AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 102/500 (20%), Positives = 217/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 305 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 363
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 364 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 418
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 419 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 468
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 528
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L +A +A+L+ +++
Sbjct: 529 QLQQELENLKEV-----LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 583
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 584 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 631
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 632 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 691
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E+ ++ +L+E
Sbjct: 692 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 751
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 752 VLAFQTMEEEKEKEQRALEN 771
Score = 44.4 bits (100), Expect = 0.001
Identities = 55/289 (19%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 624 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 683
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 684 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 743
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 744 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 804 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 859
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ + L LHE +S++ +LE
Sbjct: 860 RQSKEHICRITDLQEELRHREHHISELDKEVQHLHE---NISALTKELE 905
Score = 39.9 bits (89), Expect = 0.026
Identities = 61/287 (21%), Positives = 125/287 (43%), Gaps = 34/287 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 436 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 495
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKD--Q 208
K + + + +KD K N +++K L +++ +LK+ L + N +N++
Sbjct: 496 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGH 554
Query: 209 ISEMKKDMDELLQALEG----AQSEVEMLKKEL-VKQTSRAEQCTQLKN---QLEKQNFE 260
+ +M + ++ L + EG Q E L+ EL + + S E L N +LE++ +
Sbjct: 555 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ 614
Query: 261 FQQVTSKLKELE------YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL-- 312
++ + +KE E D W + +L L+ E + A + L
Sbjct: 615 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQL 674
Query: 313 --RDAICNKLLLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQ 356
R+ + +++V L +++ L Q ++++L +++ L +++Q
Sbjct: 675 KDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQ 721
Score = 31.9 bits (69), Expect = 6.9
Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 868 RITDLQEELRH----REHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 923
Query: 250 LKNQ-LEKQ-NFEFQQVTS-KLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
L Q L K+ E +T+ L+E R + K L ++ E+E++
Sbjct: 924 LHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMR 983
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
+ ++ K +L E+ + +E + QLEL + + V
Sbjct: 984 ESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKV 1031
>AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 50.8 bits (116), Expect = 1e-05
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 29/402 (7%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ +++ DMD ++ Q V+ K+EL K + ++ L + K+ +FQ +K
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L++ E E+ S Q + QK L + E+EV ++R + L NK + EQ+H
Sbjct: 284 LQQ-ENEQHSLVCEQLSQENQQKAL-ELKAKEEEVHQMRLDIGKL-----NK--IREQIH 334
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
+ E Q ++E H+ +K V LE + A++ + A R A++ L
Sbjct: 335 KKLHHTED-QKAEVEQHKETLKNQIV--GLEREVEASK----KQAELDRKAMDELLRERD 387
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
T+ V + + G++ + + Q +I L+K
Sbjct: 388 ILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEK------- 440
Query: 448 ERDSY-RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHA 504
ERD Y Q D +K L + + ++ + E L+ ++L A D +
Sbjct: 441 ERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNL 500
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG-PQTKVLHLTNNPAAE 563
+SK L ++E+T + + + V +L+ ++L ++ Q ++ AE
Sbjct: 501 YSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAE 560
Query: 564 AQKQISKELEAAQ--EEIKKLKVALREGGAQADPEELQQMRQ 603
QK + LE E+ + + L A+AD E L+Q ++
Sbjct: 561 LQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKE 602
Score = 38.7 bits (86), Expect = 0.060
Identities = 66/356 (18%), Positives = 146/356 (41%), Gaps = 39/356 (10%)
Query: 187 LHKQIADLKDKLLEANVSNKDQ---ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
L ++I +L + + + + DQ I ++ + +E+ + + SEV L++ L + T +
Sbjct: 123 LKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQ 182
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVT 303
++ + K + E +FQQ + Q + A + +LEKE+
Sbjct: 183 QQETERSKEEAEHAISQFQQ----------------EIQQRQNEASREFRKKEKLEKELK 226
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW-MS 362
+++A+ S + I L++ V + E LQ ++ +L E K+ +LE + M
Sbjct: 227 QIQADMDSRQTEI---KALQQYVQK---SKEELQKLEQQLKEQKILNERAAKELEQFQMR 280
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A+ +L E + ++ L R++ KL+
Sbjct: 281 NAKLQQENEQHSL--VCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH 338
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
+ E L+ +++ + RE ++ ++Q + K + L + +L+
Sbjct: 339 HTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD------ILNKN 392
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
+ + + Q DL+ H+ +A +L E+ +++EA+ R+ + L +RD
Sbjct: 393 MLKAVNATQKQTDLVKLHE-----QAKRNLEGEIQNYKDEAQKQRKIIFHLEKERD 443
Score = 34.7 bits (76), Expect = 0.98
Identities = 53/283 (18%), Positives = 123/283 (43%), Gaps = 27/283 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K+++ D+ + + +I L+ V ++E+Q L ++ K EQ +ERA ++E
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKS---KEELQKLEQQLK----EQKILNERAAKELEQ 276
Query: 151 XXXXXXXXXXXXKDEF---NTAAKEHKDLKANWDKEKTDLHKQIADL------KDKLLEA 201
+ ++E++ ++ ++H+ D+ ++++ +
Sbjct: 277 FQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKK 336
Query: 202 NVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
+DQ +E+++ + L + G + EVE KK+ ++ + ++ L K +
Sbjct: 337 LHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKA 396
Query: 262 QQVTSKLKEL-----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
T K +L + +R+ + Q AQK+ + LEKE R N+ S +
Sbjct: 397 VNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRY-INQAS---DL 452
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
K+L+ + + R + + ++ E+++KL ++ E+
Sbjct: 453 TQKVLM--NMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEA 493
>AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 50.8 bits (116), Expect = 1e-05
Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 29/402 (7%)
Query: 208 QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSK 267
++ +++ DMD ++ Q V+ K+EL K + ++ L + K+ +FQ +K
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAK 283
Query: 268 LKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVH 327
L++ E E+ S Q + QK L + E+EV ++R + L NK + EQ+H
Sbjct: 284 LQQ-ENEQHSLVCEQLSQENQQKAL-ELKAKEEEVHQMRLDIGKL-----NK--IREQIH 334
Query: 328 QLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXX 387
+ E Q ++E H+ +K V LE + A++ + A R A++ L
Sbjct: 335 KKLHHTED-QKAEVEQHKETLKNQIV--GLEREVEASK----KQAELDRKAMDELLRERD 387
Query: 388 XXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTR 447
T+ V + + G++ + + Q +I L+K
Sbjct: 388 ILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEK------- 440
Query: 448 ERDSY-RQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAA--HDPHA 504
ERD Y Q D +K L + + ++ + E L+ ++L A D +
Sbjct: 441 ERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNL 500
Query: 505 HSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIG-PQTKVLHLTNNPAAE 563
+SK L ++E+T + + + V +L+ ++L ++ Q ++ AE
Sbjct: 501 YSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAE 560
Query: 564 AQKQISKELEAAQ--EEIKKLKVALREGGAQADPEELQQMRQ 603
QK + LE E+ + + L A+AD E L+Q ++
Sbjct: 561 LQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKE 602
Score = 38.7 bits (86), Expect = 0.060
Identities = 66/356 (18%), Positives = 146/356 (41%), Gaps = 39/356 (10%)
Query: 187 LHKQIADLKDKLLEANVSNKDQ---ISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR 243
L ++I +L + + + + DQ I ++ + +E+ + + SEV L++ L + T +
Sbjct: 123 LKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQ 182
Query: 244 AEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVT 303
++ + K + E +FQQ + Q + A + +LEKE+
Sbjct: 183 QQETERSKEEAEHAISQFQQ----------------EIQQRQNEASREFRKKEKLEKELK 226
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESW-MS 362
+++A+ S + I L++ V + E LQ ++ +L E K+ +LE + M
Sbjct: 227 QIQADMDSRQTEI---KALQQYVQK---SKEELQKLEQQLKEQKILNERAAKELEQFQMR 280
Query: 363 AARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLN 422
A+ +L E + ++ L R++ KL+
Sbjct: 281 NAKLQQENEQHSL--VCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH 338
Query: 423 DLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSAR 482
+ E L+ +++ + RE ++ ++Q + K + L + +L+
Sbjct: 339 HTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD------ILNKN 392
Query: 483 VQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRD 538
+ + + Q DL+ H+ +A +L E+ +++EA+ R+ + L +RD
Sbjct: 393 MLKAVNATQKQTDLVKLHE-----QAKRNLEGEIQNYKDEAQKQRKIIFHLEKERD 443
Score = 34.7 bits (76), Expect = 0.98
Identities = 53/283 (18%), Positives = 123/283 (43%), Gaps = 27/283 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K+++ D+ + + +I L+ V ++E+Q L ++ K EQ +ERA ++E
Sbjct: 224 ELKQIQADMDSRQTEIKALQQYVQKS---KEELQKLEQQLK----EQKILNERAAKELEQ 276
Query: 151 XXXXXXXXXXXXKDEF---NTAAKEHKDLKANWDKEKTDLHKQIADL------KDKLLEA 201
+ ++E++ ++ ++H+ D+ ++++ +
Sbjct: 277 FQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKK 336
Query: 202 NVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEF 261
+DQ +E+++ + L + G + EVE KK+ ++ + ++ L K +
Sbjct: 337 LHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKA 396
Query: 262 QQVTSKLKEL-----EYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
T K +L + +R+ + Q AQK+ + LEKE R N+ S +
Sbjct: 397 VNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRY-INQAS---DL 452
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
K+L+ + + R + + ++ E+++KL ++ E+
Sbjct: 453 TQKVLM--NMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEA 493
>AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 102/500 (20%), Positives = 217/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 305 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 363
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 364 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 418
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 419 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 468
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 528
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L +A +A+L+ +++
Sbjct: 529 QLQQELENLKEV-----LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 583
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 584 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 631
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 632 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 691
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E+ ++ +L+E
Sbjct: 692 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 751
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 752 VLAFQTMEEEKEKEQRALEN 771
Score = 44.4 bits (100), Expect = 0.001
Identities = 55/289 (19%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 624 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 683
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 684 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 743
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 744 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 804 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 859
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ + L LHE +S++ +LE
Sbjct: 860 RQSKEHICRITDLQEELRHREHHISELDKEVQHLHE---NISALTKELE 905
Score = 39.9 bits (89), Expect = 0.026
Identities = 61/287 (21%), Positives = 125/287 (43%), Gaps = 34/287 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 436 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 495
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKD--Q 208
K + + + +KD K N +++K L +++ +LK+ L + N +N++
Sbjct: 496 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGH 554
Query: 209 ISEMKKDMDELLQALEG----AQSEVEMLKKEL-VKQTSRAEQCTQLKN---QLEKQNFE 260
+ +M + ++ L + EG Q E L+ EL + + S E L N +LE++ +
Sbjct: 555 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ 614
Query: 261 FQQVTSKLKELE------YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL-- 312
++ + +KE E D W + +L L+ E + A + L
Sbjct: 615 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQL 674
Query: 313 --RDAICNKLLLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQ 356
R+ + +++V L +++ L Q ++++L +++ L +++Q
Sbjct: 675 KDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQ 721
Score = 31.9 bits (69), Expect = 6.9
Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 868 RITDLQEELRH----REHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 923
Query: 250 LKNQ-LEKQ-NFEFQQVTS-KLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
L Q L K+ E +T+ L+E R + K L ++ E+E++
Sbjct: 924 LHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMR 983
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
+ ++ K +L E+ + +E + QLEL + + V
Sbjct: 984 ESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKV 1031
>AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 102/500 (20%), Positives = 217/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 305 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 363
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 364 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 418
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 419 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 468
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 528
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L +A +A+L+ +++
Sbjct: 529 QLQQELENLKEV-----LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 583
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 584 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 631
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 632 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 691
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E+ ++ +L+E
Sbjct: 692 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAH 751
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 752 VLAFQTMEEEKEKEQRALEN 771
Score = 44.4 bits (100), Expect = 0.001
Identities = 55/289 (19%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 624 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 683
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 684 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 743
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 744 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 804 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 859
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ + L LHE +S++ +LE
Sbjct: 860 RQSKEHICRITDLQEELRHREHHISELDKEVQHLHE---NISALTKELE 905
Score = 39.9 bits (89), Expect = 0.026
Identities = 61/287 (21%), Positives = 125/287 (43%), Gaps = 34/287 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 436 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 495
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKD--Q 208
K + + + +KD K N +++K L +++ +LK+ L + N +N++
Sbjct: 496 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGH 554
Query: 209 ISEMKKDMDELLQALEG----AQSEVEMLKKEL-VKQTSRAEQCTQLKN---QLEKQNFE 260
+ +M + ++ L + EG Q E L+ EL + + S E L N +LE++ +
Sbjct: 555 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ 614
Query: 261 FQQVTSKLKELE------YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL-- 312
++ + +KE E D W + +L L+ E + A + L
Sbjct: 615 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQL 674
Query: 313 --RDAICNKLLLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQ 356
R+ + +++V L +++ L Q ++++L +++ L +++Q
Sbjct: 675 KDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQ 721
Score = 31.9 bits (69), Expect = 6.9
Identities = 37/168 (22%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 868 RITDLQEELRH----REHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 923
Query: 250 LKNQ-LEKQ-NFEFQQVTS-KLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRL 305
L Q L K+ E +T+ L+E R + K L ++ E+E++
Sbjct: 924 LHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMR 983
Query: 306 RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
+ ++ K +L E+ + +E + QLEL + + V
Sbjct: 984 ESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKV 1031
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/287 (19%), Positives = 134/287 (46%), Gaps = 15/287 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDM 148
+ KR K L A+ + L++ + I + L E E A+ ++ K E + D+
Sbjct: 1333 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1392
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN-----V 203
+++ + +E +++ ++++ D+++ + K + +A+ +
Sbjct: 1393 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1452
Query: 204 SN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT--SRAE-QCTQLKNQLEKQNF 259
++ + Q+ E K+ EL + L+ QS+VE L++ +V ++ SR E + +L+ +LE +
Sbjct: 1453 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1512
Query: 260 E---FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
+ + + S+LKE + +D + ++ +K + + T+ E + ++A
Sbjct: 1513 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1572
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
++ E ++ L S A Q +Q +L A ++ +++ +E M +
Sbjct: 1573 ASRKKHELEM-DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMES 1618
Score = 43.6 bits (98), Expect = 0.002
Identities = 93/434 (21%), Positives = 168/434 (38%), Gaps = 38/434 (8%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXX 157
L K Q+ LE++V Q E ++ + ++EQ K R E + M
Sbjct: 1213 LAKVKKQLRDLEAKVKDQ-----EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEME 1267
Query: 158 XXXXXKDEFNTAA-KEHKDLKANWDKEKTDLHKQIAD---LKDKL--LEANVSNKDQISE 211
+E + K+ K ++ ++E D K + + L+ KL L V+ +D SE
Sbjct: 1268 SRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE 1327
Query: 212 --MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++KD+ L AQ ++ LK + + QLKNQLE+ F K
Sbjct: 1328 KRLRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESEFTCAAAVKARK 1383
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ- 325
+E E + D ++KTA + + + EK + R E D N+L+ + +
Sbjct: 1384 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL-EEDQED--MNELMKKHKA 1440
Query: 326 -VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
V Q + + + +Q +L EA + ++ +L++ S + +E + + +
Sbjct: 1441 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS--QVEFLEQSMVDKSLVSRQEA 1498
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
L + LK +K T + + ++ RLQ++L
Sbjct: 1499 KIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL-- 1556
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYR---DLIAAH 500
RD+ + + KE + E + L A Q L+ L+ ++ DL AA
Sbjct: 1557 ----RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAI 1612
Query: 501 DPHAHSKALESLRN 514
+ S E L N
Sbjct: 1613 EDEMESDENEDLIN 1626
Score = 37.5 bits (83), Expect = 0.14
Identities = 67/365 (18%), Positives = 159/365 (43%), Gaps = 22/365 (6%)
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANE 309
+ Q+ ++ E QQ+ SKL++ E ER+ + + S + R+ + +EL E +
Sbjct: 929 EEQIRNKDEEIQQLRSKLEKAEKERN---ELRLNSDRLESRISELTSELTDERNTGESAS 985
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG- 368
+ L +L E+++ +L ++ +AL+ Q+E+ E +V +E++L + AA +G
Sbjct: 986 QLLDAETAERLRAEKEMKELQTQYDALKK-QMEVMEMEV----MEARL---IRAAEINGE 1037
Query: 369 VESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
V+ A E L +++ + + + +L DL
Sbjct: 1038 VDDDDA---GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADS 1094
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYE---KELTVTLCGEEGAGSVALLSARVQQ 485
+ + + +L+K+ +T E + L+ + EL + S A A+ ++
Sbjct: 1095 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1154
Query: 486 LEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
L++ LQ +D++ A + + + LE ++ + ++ ++ + +Q ASL
Sbjct: 1155 LQREKLQREKDMLLA-EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL 1213
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
++ Q + L E + + ++ ++ +L++ + E Q +E++ ++
Sbjct: 1214 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM-ERMRQTHSKEMESRDEE 1272
Query: 605 LENSR 609
+E +R
Sbjct: 1273 VEEAR 1277
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/287 (19%), Positives = 134/287 (46%), Gaps = 15/287 (5%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK--ASLIEQHKRDERAVSDM 148
+ KR K L A+ + L++ + I + L E E A+ ++ K E + D+
Sbjct: 1649 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1708
Query: 149 EDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEAN-----V 203
+++ + +E +++ ++++ D+++ + K + +A+ +
Sbjct: 1709 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1768
Query: 204 SN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQT--SRAE-QCTQLKNQLEKQNF 259
++ + Q+ E K+ EL + L+ QS+VE L++ +V ++ SR E + +L+ +LE +
Sbjct: 1769 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT 1828
Query: 260 E---FQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAI 316
+ + + S+LKE + +D + ++ +K + + T+ E + ++A
Sbjct: 1829 QVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1888
Query: 317 CNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSA 363
++ E ++ L S A Q +Q +L A ++ +++ +E M +
Sbjct: 1889 ASRKKHELEM-DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMES 1934
Score = 44.0 bits (99), Expect = 0.002
Identities = 93/436 (21%), Positives = 169/436 (38%), Gaps = 38/436 (8%)
Query: 99 LIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHK-RDERAVSDMEDXXXXXXX 157
L K Q+ LE++V Q E ++ + ++EQ K R E + M
Sbjct: 1529 LAKVKKQLRDLEAKVKDQ-----EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEME 1583
Query: 158 XXXXXKDEFNTAA-KEHKDLKANWDKEKTDLHKQIAD---LKDKL--LEANVSNKDQISE 211
+E + K+ K ++ ++E D K + + L+ KL L V+ +D SE
Sbjct: 1584 SRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE 1643
Query: 212 --MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
++KD+ L AQ ++ LK + + QLKNQLE+ F K
Sbjct: 1644 KRLRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESEFTCAAAVKARK 1699
Query: 270 ELEYERDSYK---DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQ- 325
+E E + D ++KTA + + + EK + R E D N+L+ + +
Sbjct: 1700 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL-EEDQED--MNELMKKHKA 1756
Query: 326 -VHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALG 384
V Q + + + +Q +L EA + ++ +L++ S + +E + + +
Sbjct: 1757 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS--QVEFLEQSMVDKSLVSRQEA 1814
Query: 385 XXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLL 444
L + LK +K T + + ++ RLQ++L
Sbjct: 1815 KIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQL-- 1872
Query: 445 VTRERDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQ-GYR---DLIAAH 500
RD+ + + KE + E + L A Q L+ L+ ++ DL AA
Sbjct: 1873 ----RDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAI 1928
Query: 501 DPHAHSKALESLRNEV 516
+ S E L N +
Sbjct: 1929 EDEMESDENEDLINSL 1944
Score = 37.5 bits (83), Expect = 0.14
Identities = 67/365 (18%), Positives = 159/365 (43%), Gaps = 22/365 (6%)
Query: 251 KNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNM-AELEKEVTRLRANE 309
+ Q+ ++ E QQ+ SKL++ E ER+ + + S + R+ + +EL E +
Sbjct: 1245 EEQIRNKDEEIQQLRSKLEKAEKERN---ELRLNSDRLESRISELTSELTDERNTGESAS 1301
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHG- 368
+ L +L E+++ +L ++ +AL+ Q+E+ E +V +E++L + AA +G
Sbjct: 1302 QLLDAETAERLRAEKEMKELQTQYDALKK-QMEVMEMEV----MEARL---IRAAEINGE 1353
Query: 369 VESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVR 428
V+ A E L +++ + + + +L DL
Sbjct: 1354 VDDDDA---GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADS 1410
Query: 429 KNQESLIHRLQKRLLLVTRERDSYRQQLDCYE---KELTVTLCGEEGAGSVALLSARVQQ 485
+ + + +L+K+ +T E + L+ + EL + S A A+ ++
Sbjct: 1411 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1470
Query: 486 LEK-SLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASL 544
L++ LQ +D++ A + + + LE ++ + ++ ++ + +Q ASL
Sbjct: 1471 LQREKLQREKDMLLA-EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL 1529
Query: 545 ERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQ 604
++ Q + L E + + ++ ++ +L++ + E Q +E++ ++
Sbjct: 1530 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM-ERMRQTHSKEMESRDEE 1588
Query: 605 LENSR 609
+E +R
Sbjct: 1589 VEEAR 1593
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/355 (19%), Positives = 145/355 (40%), Gaps = 22/355 (6%)
Query: 18 RRVINTEPPKD-KLSASTNLNFSDSTQS----IKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
RR +++ P D + S++ + + +S Q ++E L N + ++ DK
Sbjct: 403 RRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK 462
Query: 73 RLRR-DSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
++ D GN S +++ + + + +I + + + ++ R+ + E +
Sbjct: 463 IMKELDEEGNQRRNLEST--VSQIEKEKMLLQHRINEYQRKAEQENEKRRNV-----ENE 515
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI 191
S ++ D + VS +E N + D K T++ K I
Sbjct: 516 VSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSI 575
Query: 192 ADLKD---KLLEANVSNKDQISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRA 244
+ L+ +L E N ++ S+ KD +L LE + + EM+ + TS
Sbjct: 576 SQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 635
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVT 303
E+ LK+ LEK E ++ L E E+++ + D + K+ Q+RL E +VT
Sbjct: 636 EEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRL-EQEVNEHKVT 694
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ R ++ + + E +L EA + + + + + + S ++ L+
Sbjct: 695 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLK 749
Score = 48.4 bits (110), Expect = 7e-05
Identities = 92/453 (20%), Positives = 192/453 (42%), Gaps = 55/453 (12%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIAD---LKDKLLEANVSNKDQISEMKKDMDELLQALE 224
T++ K L+ + K L +Q+ + LKD++ + ++ ++ ++ K++DE
Sbjct: 416 TSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 475
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+S V ++KE + R + + + E++N + + V +++ L+ + + K
Sbjct: 476 NLESTVSQIEKEKMLLQHR---INEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQN 532
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
S+ A ++L ++L+K++ AN+ LR + L + +++ + L+ + EL
Sbjct: 533 SQLANEKL---SQLQKQLE--EAND-LLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E L + +SQ + + L+ LE+ L
Sbjct: 587 ERNRILENSKSQTD-----------KDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 635
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
EEV LK+ +K G+ RK + +++ +K E+++ L+ K L
Sbjct: 636 EEVKHLKHNLEKVEGE-------RKEAQDMLNHSEK-------EKNNLEIDLNYKLKSLQ 681
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + AR+ +S++ A S A+ + ++ RE E
Sbjct: 682 QRL--EQEVNEHKVTKARLTDKHQSIE-----------EAKSVAMCEMEKKLKEEREARE 728
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
A V ++ Q +L L++ Q K+ HLT N + + L+ QE K+L +
Sbjct: 729 KAENRVVQIEKQCSMLDVDLKQ--SQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786
Query: 585 --ALREGGAQADP-EELQQMRQQLENSRIKLKR 614
L+ +AD + L++ +Q N+ ++ KR
Sbjct: 787 QNELKTQAFEADNLKGLEKQMKQEINTLLEAKR 819
Score = 38.3 bits (85), Expect = 0.080
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKL-LEANVSN--KDQISEMKKDM 216
K E NT + + L+ A K+ Q+ +L+D+L E S K Q+ E+K+++
Sbjct: 808 KQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEI 867
Query: 217 DEL----LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+E L+ ++ Q+E E L +L ++AE + LE+Q FE Q + K
Sbjct: 868 EEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRN 927
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN-----KLLLEEQVH 327
+ + KD T S+ + + L K++ LR L + + KL EE++
Sbjct: 928 RQEITDKD-HTVSRLEEAN----SMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEIS 982
Query: 328 QLTSRVE 334
L + E
Sbjct: 983 NLKAAFE 989
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/355 (19%), Positives = 145/355 (40%), Gaps = 22/355 (6%)
Query: 18 RRVINTEPPKD-KLSASTNLNFSDSTQS----IKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
RR +++ P D + S++ + + +S Q ++E L N + ++ DK
Sbjct: 403 RRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK 462
Query: 73 RLRR-DSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
++ D GN S +++ + + + +I + + + ++ R+ + E +
Sbjct: 463 IMKELDEEGNQRRNLEST--VSQIEKEKMLLQHRINEYQRKAEQENEKRRNV-----ENE 515
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI 191
S ++ D + VS +E N + D K T++ K I
Sbjct: 516 VSTLKNQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSI 575
Query: 192 ADLKD---KLLEANVSNKDQISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRA 244
+ L+ +L E N ++ S+ KD +L LE + + EM+ + TS
Sbjct: 576 SQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 635
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVT 303
E+ LK+ LEK E ++ L E E+++ + D + K+ Q+RL E +VT
Sbjct: 636 EEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRL-EQEVNEHKVT 694
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ R ++ + + E +L EA + + + + + + S ++ L+
Sbjct: 695 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLK 749
Score = 48.8 bits (111), Expect = 6e-05
Identities = 92/453 (20%), Positives = 192/453 (42%), Gaps = 55/453 (12%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIAD---LKDKLLEANVSNKDQISEMKKDMDELLQALE 224
T++ K L+ + K L +Q+ + LKD++ + ++ ++ ++ K++DE
Sbjct: 416 TSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 475
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+S V ++KE + R + + + E++N + + V +++ L+ + + K
Sbjct: 476 NLESTVSQIEKEKMLLQHR---INEYQRKAEQENEKRRNVENEVSTLKNQLEDLKKVSQN 532
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
S+ A ++L ++L+K++ AN+ LR + L + +++ + L+ + EL
Sbjct: 533 SQLANEKL---SQLQKQLE--EAND-LLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E L + +SQ + + L+ LE+ L
Sbjct: 587 ERNRILENSKSQTD-----------KDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 635
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
EEV LK+ +K G+ RK + +++ +K E+++ L+ K L
Sbjct: 636 EEVKHLKHNLEKVEGE-------RKEAQDMLNHSEK-------EKNNLEIDLNYKLKSLQ 681
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + AR+ +S++ A S A+ + ++ RE E
Sbjct: 682 QRL--EQEVNEHKVTKARLTDKHQSIE-----------EAKSVAMCEMEKKLKEEREARE 728
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
A V ++ Q +L L++ Q K+ HLT N + + L+ QE K+L +
Sbjct: 729 KAENRVVQIEKQCSMLDVDLKQ--SQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786
Query: 585 --ALREGGAQADP-EELQQMRQQLENSRIKLKR 614
L+ +AD + L++ +Q N+ ++ KR
Sbjct: 787 QNELKTQAFEADNLKGLEKQMKQEINTLLEAKR 819
Score = 38.3 bits (85), Expect = 0.080
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKL-LEANVSN--KDQISEMKKDM 216
K E NT + + L+ A K+ Q+ +L+D+L E S K Q+ E+K+++
Sbjct: 808 KQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEI 867
Query: 217 DEL----LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+E L+ ++ Q+E E L +L ++AE + LE+Q FE Q + K
Sbjct: 868 EEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRN 927
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN-----KLLLEEQVH 327
+ + KD T S+ + + L K++ LR L + + KL EE++
Sbjct: 928 RQEITDKD-HTVSRLEEAN----SMLTKDIEILRRENEELTERMKKAEEEYKLEKEEEIS 982
Query: 328 QLTSRVE 334
L + E
Sbjct: 983 NLKAAFE 989
>BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein.
Length = 954
Score = 50.4 bits (115), Expect = 2e-05
Identities = 96/557 (17%), Positives = 229/557 (41%), Gaps = 44/557 (7%)
Query: 94 RLKIDLIAAKAQITKLESRVNHQHTIRK--EMQILFEEEKASLIEQHKRDERAVSDMEDX 151
R + + I ++ +I + ++R + +R+ +++ + ++ L E + E ++E
Sbjct: 132 RSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKTEELEKQ 191
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLK------DKLLEANVSN 205
+ E + ++E +L K DLHK+ +L +L + + N
Sbjct: 192 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGN 251
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQ-LEKQN---FEF 261
I +++++D ++ ++ ++ LK E Q R Q KN+ LEK + +
Sbjct: 252 SITIDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQL 311
Query: 262 QQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKL 320
+ L+++ E + K ++ +T ++ E E+ + A LR + KL
Sbjct: 312 ESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLRSRVDLKL 371
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSS-------VESQLESWMSAARAHGVESAG 373
+++ L + + L+ VQ E K++++ + Q+E+ HG +AG
Sbjct: 372 ---QELQHLKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHG-RTAG 427
Query: 374 AL---RDALESALG----XXXXXXXXXXXXXXXXXHLTEEVATLKYERDK----ATGKLN 422
A+ + LE + L V+ L+ E+ K + +L
Sbjct: 428 AMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 487
Query: 423 DLTTVRKNQESLIHRL---QKRLLLVTRERDSYRQQL--DCYEKELTVTLCGEEGAGSVA 477
+ +++ ++ L++ + + L ++ E + ++ E E+T + + +
Sbjct: 488 AVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQS 547
Query: 478 LLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRDVTKLRTQR 537
L + + KS++G D A K + + R ++ + + + +T ++
Sbjct: 548 ELE-QTRNTLKSMEG-SDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEK 605
Query: 538 DLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREGGAQ-ADPE 596
L ++ + + N A + + + +E++ ++VAL + Q A+ +
Sbjct: 606 HFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVALDKASLQFAECQ 665
Query: 597 ELQQMRQQLENSRIKLK 613
++ Q RQ+ E+ R+KL+
Sbjct: 666 DIIQ-RQEQESVRLKLQ 681
Score = 45.6 bits (103), Expect = 5e-04
Identities = 60/261 (22%), Positives = 114/261 (43%), Gaps = 27/261 (10%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E K LKI A+I +LE+RV+ E EK L+ RAV D++
Sbjct: 446 ELKELKILKDKKDAKIRELEARVSD-----------LELEKVKLVNAGSERLRAVKDIKQ 494
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
+ E N ++E++ LK N+ + ++ LK +L A S
Sbjct: 495 ERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQ-------S 547
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQ-TSRAEQCTQLKNQLEKQNFEFQQVTSKLK 269
E+++ + L+++EG+ + + KQ T++ Q L+++++ F + +T+ K
Sbjct: 548 ELEQTRN-TLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQ---FLEEAMTNANK 603
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN-KLLLEEQVHQ 328
E + ++ + T MA E EV LR+ ER L++ + N ++ L++ Q
Sbjct: 604 EKHFLKEEKSKLSQELSTVATEKNKMAG-ELEV--LRSQERRLKEKVTNMEVALDKASLQ 660
Query: 329 LTSRVEALQPVQLELHEAKVK 349
+ +Q + E K++
Sbjct: 661 FAECQDIIQRQEQESVRLKLQ 681
Score = 43.6 bits (98), Expect = 0.002
Identities = 88/475 (18%), Positives = 192/475 (40%), Gaps = 41/475 (8%)
Query: 134 LIEQHK-RDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIA 192
L++QH+ R E+ +S+ E + + N+ + + ++ + + +Q++
Sbjct: 102 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLS 161
Query: 193 DLKDKLLEANVSN-KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLK 251
D LE+ VS + ++ E K+ ++ + LE ++ + EL + + +Q +Q
Sbjct: 162 D-----LESTVSQLRSELREAKRMYEDKTEELE---KQLVLANSELTEARTERDQFSQES 213
Query: 252 NQLEKQNFE-FQQVTSKLKELEYERDSYKD-WQT---QSKTAQKRLCNMAELEKEVTRLR 306
L+ Q + + + KEL E++ K W S T + EV RL
Sbjct: 214 GNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLE 273
Query: 307 ANERSLRD-----------AICNKLLLEEQVHQLTSRVEA----LQPVQLELHEAKVKLS 351
A ++L+ AI K E+V LT+++E+ L+ V EL K+ L
Sbjct: 274 ALLKALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE 333
Query: 352 SVESQLESWMSA--ARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVAT 409
S E + ++ + +E+ A L S + ++ E
Sbjct: 334 SSERTISDLTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA 393
Query: 410 LKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKEL-TVTLC 468
LK + + + L +N L+ + + + E+ ++++ EL + +
Sbjct: 394 LKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKIL 453
Query: 469 GEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARR 528
++ + L ARV LE L+ + + A + +A++ ++ E + E + +R
Sbjct: 454 KDKKDAKIRELEARVSDLE--LEKVKLVNAGSE---RLRAVKDIKQERDQLLNEVKTSRS 508
Query: 529 DVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLK 583
++ L + ++L + +++ + +T N K ELE + +K ++
Sbjct: 509 ELNNLSEEYEVLKRNFRN---KSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSME 560
>BC047438-1|AAH47438.1| 354|Homo sapiens homer homolog 1
(Drosophila) protein.
Length = 354
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 2/145 (1%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALE 224
E K+ K A + +E LHK++ +L+ +AN + + +E+ + + EL +AL+
Sbjct: 203 ESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAVHTHK-TELNQTIQELEEALK 261
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+ E+E LK+E+ EQ L +L++ + + +L +LE + ++ Q
Sbjct: 262 LREEEIERLKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRLEKSQNEQEA 321
Query: 285 SKTAQKRLCNMAELE-KEVTRLRAN 308
+ K L + + + E+T LR N
Sbjct: 322 FRNNLKTLLEILDGKIFELTELRDN 346
Score = 33.1 bits (72), Expect = 3.0
Identities = 23/105 (21%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQI 568
LES N V +W+++ + + +L + LE + Q +H + +++
Sbjct: 202 LESTAN-VKQWKQQLAAYQEEAERLHKR----VTELECVSSQANAVHTHKTELNQTIQEL 256
Query: 569 SKELEAAQEEIKKLKVALREGGAQADPEELQQMRQQLENSRIKLK 613
+ L+ +EEI++LK + A+ E+ + Q+L+ I+ K
Sbjct: 257 EEALKLREEEIERLKQEI--DNARELQEQRDSLTQKLQEVEIRNK 299
>AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein.
Length = 2069
Score = 50.4 bits (115), Expect = 2e-05
Identities = 99/458 (21%), Positives = 185/458 (40%), Gaps = 33/458 (7%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQISEMKKDMDELL--Q 221
K A K +L KQI++LK K L + N N++++ E+ + + E+L +
Sbjct: 1545 KQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQK 1604
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
E S +E ++E E+C Q + E +V + ++ E KD
Sbjct: 1605 EKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKD 1664
Query: 281 WQTQSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
+ + R ++++ +++++ L NE+ L++ K L E+++ ++ +
Sbjct: 1665 -ELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSEELNSCVDKLAKSSLL 1719
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ + K + S E Q S S A E L D +++
Sbjct: 1720 EHRIATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQE 1778
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER-DSYRQQLDC 458
L +EV +L + A GK S +H QKRL + + QQL
Sbjct: 1779 KEALKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLW 1836
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAAHDPHAHSKALESLRN 514
E E + T+ + + +V+QLE +L Q + + +P K SL+
Sbjct: 1837 QENERSQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKL--SLKR 1893
Query: 515 EVTRWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
E ++++E A R V+++ + +++L T LE G + K + L + E Q S
Sbjct: 1894 ECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL-DEQLMEMQHLRSTATP 1952
Query: 574 AAQEEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
+ L++ ++ E+ LQ RQ L+ RI
Sbjct: 1953 SPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 1990
Score = 44.8 bits (101), Expect = 0.001
Identities = 55/257 (21%), Positives = 108/257 (42%), Gaps = 29/257 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1698 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1756
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1757 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1812
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E +Q+ V+ K EL T E+ QL++ L
Sbjct: 1813 HNQQKRLSWDKLDHLMNEEQQLLWQENERSQTMVQNTKAEL---THSREKVRQLESNLLP 1869
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1870 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1929
Query: 313 RDAICNKLLLEEQVHQL 329
+ ++ L+EQ+ ++
Sbjct: 1930 KK---KQVKLDEQLMEM 1943
Score = 39.5 bits (88), Expect = 0.035
Identities = 38/172 (22%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 632 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 687
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 688 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 747
Query: 287 TAQKRLCNMAE---LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
Q++L ++ E LEKE R E+ R+ + +E + ++ TS++EA
Sbjct: 748 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEA 799
Score = 36.3 bits (80), Expect = 0.32
Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 42/296 (14%)
Query: 119 IRKEMQILFEEEKASLIEQH--KRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKE---- 172
+ +E++ +E+ SL+E+H +++E +E + E N +
Sbjct: 741 LTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQ 800
Query: 173 -HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
D + ++ ++ L + +L + +++ S+ + + DEL Q AQ E
Sbjct: 801 FQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQ---E 857
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEF--------QQVTSKLKEL----EYERDSYK 279
+LK+ L ++ + + TQ + LEK E QQ+ L++L E ++
Sbjct: 858 LLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSMLS 917
Query: 280 DWQTQSKTAQKR--------LCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVH 327
D + K++ KR LC E+ + RL R + +KLL E +H
Sbjct: 918 DQILELKSSHKRELREREEVLCQAGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 977
Query: 328 QLT----SRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
+ T R A ++ ++K+K +S S L++ VE GAL
Sbjct: 978 KATCETADRERAEMSTEISRLQSKIKEMQQATSPLSMLQNGCQVIGEEEVEGDGAL 1033
Score = 33.5 bits (73), Expect = 2.3
Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 24/173 (13%)
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTSRAEQCTQLKNQ--LE 255
A S K +I + + +D++++ E +S++ E LK + + + +N+ L
Sbjct: 361 ALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLR 420
Query: 256 KQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
K + E+++ + LK EL ER+ Q + ++RL ELE+E+ + + E +RD
Sbjct: 421 KLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELEQEIEKAKTEENYIRD 471
Query: 315 AICNKL---------LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ L LLE + L + L P E + +L+ + ++ E
Sbjct: 472 RLALSLKENSRLENELLENAENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYE 524
>AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein.
Length = 2029
Score = 50.4 bits (115), Expect = 2e-05
Identities = 99/458 (21%), Positives = 185/458 (40%), Gaps = 33/458 (7%)
Query: 174 KDLKANWDKEKTDLHKQIADLKDK----------LLEANVSNKDQISEMKKDMDELL--Q 221
K A K +L KQI++LK K L + N N++++ E+ + + E+L +
Sbjct: 1545 KQENAAVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQK 1604
Query: 222 ALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD 280
E S +E ++E E+C Q + E +V + ++ E KD
Sbjct: 1605 EKEPGNSALEEREQEKFNLKEELERCKVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKD 1664
Query: 281 WQTQSKTAQKRLCNMAELEKEVTR-LRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV 339
+ + R ++++ +++++ L NE+ L++ K L E+++ ++ +
Sbjct: 1665 -ELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE----KEALSEELNSCVDKLAKSSLL 1719
Query: 340 QLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXX 399
+ + K + S E Q S S A E L D +++
Sbjct: 1720 EHRIATMKQEQKSWEHQSASLKSQLVA-SQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQE 1778
Query: 400 XXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRER-DSYRQQLDC 458
L +EV +L + A GK S +H QKRL + + QQL
Sbjct: 1779 KEALKQEVMSLHKQLQNAGGK--SWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQQLLW 1836
Query: 459 YEKELTVTLCGEEGAGSVALLSARVQQLEKSL----QGYRDLIAAHDPHAHSKALESLRN 514
E E + T+ + + +V+QLE +L Q + + +P K SL+
Sbjct: 1837 QENERSQTMV-QNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKL--SLKR 1893
Query: 515 EVTRWREEAEGARRDVTKLRT-QRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELE 573
E ++++E A R V+++ + +++L T LE G + K + L + E Q S
Sbjct: 1894 ECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGLKKKQVKL-DEQLMEMQHLRSTATP 1952
Query: 574 AAQEEIKKLKVALREGGAQADPEE-LQQMRQQLENSRI 610
+ L++ ++ E+ LQ RQ L+ RI
Sbjct: 1953 SPSPHAWDLQLLQQQACPMVPREQFLQLQRQLLQAERI 1990
Score = 44.8 bits (101), Expect = 0.001
Identities = 55/257 (21%), Positives = 108/257 (42%), Gaps = 29/257 (11%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +L + ++ K S + H+ K+ Q +E + ASL Q + V ++ED
Sbjct: 1698 EKEALSEELNSCVDKLAK-SSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLED 1756
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK---- 206
K + +E + LK +E LHKQ+ + K ++
Sbjct: 1757 TVQNVNLQMSRMKSDLRVTQQEKEALK----QEVMSLHKQLQNAGGKSWAPEIATHPSGL 1812
Query: 207 ---------DQISEMKKDMDELL-QALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEK 256
D++ + + +LL Q E +Q+ V+ K EL T E+ QL++ L
Sbjct: 1813 HNQQKRLSWDKLDHLMNEEQQLLWQENERSQTMVQNTKAEL---THSREKVRQLESNLLP 1869
Query: 257 QNFEFQQVTSKLKELEYERDSYK----DWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
++ + + + E E+ S K +Q + A +++ M LE+E+ + L
Sbjct: 1870 KHQKHLNPSGTMNPTEQEKLSLKRECDQFQKEQSPANRKVSQMNSLEQELETIHLENEGL 1929
Query: 313 RDAICNKLLLEEQVHQL 329
+ ++ L+EQ+ ++
Sbjct: 1930 KK---KQVKLDEQLMEM 1943
Score = 39.5 bits (88), Expect = 0.035
Identities = 38/172 (22%), Positives = 83/172 (48%), Gaps = 11/172 (6%)
Query: 171 KEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV 230
K +++K + E L KQI+DLK+++ E + Q + +K+ E E + ++
Sbjct: 632 KAQENMKQRHENETHTLEKQISDLKNEIAEL----QGQAAVLKEAHHEATCRHEEEKKQL 687
Query: 231 EML---KKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKD-WQTQSK 286
++ +K +++ R + +LK +L + F++ L+ + + + Q +
Sbjct: 688 QVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQ 747
Query: 287 TAQKRLCNMAE---LEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
Q++L ++ E LEKE R E+ R+ + +E + ++ TS++EA
Sbjct: 748 FHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEA 799
Score = 36.3 bits (80), Expect = 0.32
Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 42/296 (14%)
Query: 119 IRKEMQILFEEEKASLIEQH--KRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKE---- 172
+ +E++ +E+ SL+E+H +++E +E + E N +
Sbjct: 741 LTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQ 800
Query: 173 -HKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVE 231
D + ++ ++ L + +L + +++ S+ + + DEL Q AQ E
Sbjct: 801 FQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQECAEAQ---E 857
Query: 232 MLKKELVKQTSRAEQCTQLKNQLEKQNFEF--------QQVTSKLKEL----EYERDSYK 279
+LK+ L ++ + + TQ + LEK E QQ+ L++L E ++
Sbjct: 858 LLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSETQQSMLS 917
Query: 280 DWQTQSKTAQKR--------LCNMAELEK----EVTRLRANERSLRDAICNKLLLEEQVH 327
D + K++ KR LC E+ + RL R + +KLL E +H
Sbjct: 918 DQILELKSSHKRELREREEVLCQAGASEQLASQRLERLEMEHDQERQEMMSKLLAMENIH 977
Query: 328 QLT----SRVEALQPVQLELHEAKVK----LSSVESQLESWMSAARAHGVESAGAL 375
+ T R A ++ ++K+K +S S L++ VE GAL
Sbjct: 978 KATCETADRERAEMSTEISRLQSKIKEMQQATSPLSMLQNGCQVIGEEEVEGDGAL 1033
Score = 33.5 bits (73), Expect = 2.3
Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 24/173 (13%)
Query: 201 ANVSNKDQISEMKKDMDELLQALEGAQSEV---EMLKKELVKQTSRAEQCTQLKNQ--LE 255
A S K +I + + +D++++ E +S++ E LK + + + +N+ L
Sbjct: 361 ALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLR 420
Query: 256 KQNFEFQQVTSKLK-ELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
K + E+++ + LK EL ER+ Q + ++RL ELE+E+ + + E +RD
Sbjct: 421 KLDEEYKERIAALKNELRKERE-----QILQQAGKQRL----ELEQEIEKAKTEENYIRD 471
Query: 315 AICNKL---------LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ L LLE + L + L P E + +L+ + ++ E
Sbjct: 472 RLALSLKENSRLENELLENAENVLAEKFGDLDPSSAEFFLQEERLTQMRNEYE 524
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/355 (19%), Positives = 145/355 (40%), Gaps = 22/355 (6%)
Query: 18 RRVINTEPPKD-KLSASTNLNFSDSTQS----IKEGLSNLLTFGKRKSSIGSVDDVTPDK 72
RR +++ P D + S++ + + +S Q ++E L N + ++ DK
Sbjct: 81 RRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK 140
Query: 73 RLRR-DSSGNGTTAPPSPWETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEK 131
++ D GN S +++ + + + +I + + + ++ R+ + E +
Sbjct: 141 IMKELDEEGNQRRNLEST--VSQIEKEKMLLQHRINEYQRKAEQENEKRRNV-----ENE 193
Query: 132 ASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQI 191
S ++ D + VS +E N + D K T++ K I
Sbjct: 194 VSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSI 253
Query: 192 ADLKD---KLLEANVSNKDQISEMKKDMDELLQALEGAQSE----VEMLKKELVKQTSRA 244
+ L+ +L E N ++ S+ KD +L LE + + EM+ + TS
Sbjct: 254 SQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 313
Query: 245 EQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNMAELEKEVT 303
E+ LK+ LEK E ++ L E E+++ + D + K+ Q+RL E +VT
Sbjct: 314 EEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRL-EQEVNEHKVT 372
Query: 304 RLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ R ++ + + E +L EA + + + + + + S ++ L+
Sbjct: 373 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLK 427
Score = 48.4 bits (110), Expect = 7e-05
Identities = 92/453 (20%), Positives = 192/453 (42%), Gaps = 55/453 (12%)
Query: 168 TAAKEHKDLKANWDKEKTDLHKQIAD---LKDKLLEANVSNKDQISEMKKDMDELLQALE 224
T++ K L+ + K L +Q+ + LKD++ + ++ ++ ++ K++DE
Sbjct: 94 TSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 153
Query: 225 GAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQ 284
+S V ++KE + R + + + E++N + + V +++ L+ + + K
Sbjct: 154 NLESTVSQIEKEKMLLQHR---INEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQN 210
Query: 285 SKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELH 344
S+ A ++L ++L+K++ AN+ LR + L + +++ + L+ + EL
Sbjct: 211 SQLANEKL---SQLQKQLE--EAND-LLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 264
Query: 345 EAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLT 404
E L + +SQ + + L+ LE+ L
Sbjct: 265 ERNRILENSKSQTD-----------KDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQ 313
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELT 464
EEV LK+ +K G+ RK + +++ +K E+++ L+ K L
Sbjct: 314 EEVKHLKHNLEKVEGE-------RKEAQDMLNHSEK-------EKNNLEIDLNYKLKSLQ 359
Query: 465 VTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAE 524
L E+ + AR+ +S++ A S A+ + ++ RE E
Sbjct: 360 QRL--EQEVNEHKVTKARLTDKHQSIE-----------EAKSVAMCEMEKKLKEEREARE 406
Query: 525 GARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKV 584
A V ++ Q +L L++ Q K+ HLT N + + L+ QE K+L +
Sbjct: 407 KAENRVVQIEKQCSMLDVDLKQ--SQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 464
Query: 585 --ALREGGAQADP-EELQQMRQQLENSRIKLKR 614
L+ +AD + L++ +Q N+ ++ KR
Sbjct: 465 QNELKTQAFEADNLKGLEKQMKQEINTLLEAKR 497
Score = 38.3 bits (85), Expect = 0.080
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 163 KDEFNTAAKEHKDLK---ANWDKEKTDLHKQIADLKDKL-LEANVSN--KDQISEMKKDM 216
K E NT + + L+ A K+ Q+ +L+D+L E S K Q+ E+K+++
Sbjct: 486 KQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEI 545
Query: 217 DEL----LQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELE 272
+E L+ ++ Q+E E L +L ++AE + LE+Q FE Q + K
Sbjct: 546 EEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRN 605
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICN-----KLLLEEQVH 327
+ + KD T S+ + + L K++ LR L + + KL EE++
Sbjct: 606 RQEITDKD-HTVSRLEEAN----SMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEIS 660
Query: 328 QLTSRVE 334
L + E
Sbjct: 661 NLKAAFE 667
>U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1b
protein.
Length = 1202
Score = 50.0 bits (114), Expect = 2e-05
Identities = 57/265 (21%), Positives = 113/265 (42%), Gaps = 10/265 (3%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS-DME 149
E ++K L + + +T+LE ++ T RK++ + EE + +++ R+ A DME
Sbjct: 265 EQSQMKERLASLSSHVTELEEDLD---TARKDL--IKSEEMNTKLQRDVREAMAQKEDME 319
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ + E T+ + D N K +H+Q D K++ L+ + +Q
Sbjct: 320 ERITTLEKRYLAAQREA-TSVHDLNDKLENEIANKDSMHRQTED-KNRQLQERLELAEQK 377
Query: 210 SEMKKDMDELLQALEGAQSE-VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
+ E L +E ++ V L K + + E+ Q++ QLE++N E Q+ +
Sbjct: 378 LQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQRE 437
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
K E D + + + L++ + L LR+ K LEE H
Sbjct: 438 KMNEEHNKRLSDTVDKLLSESNERLQL-HLKERMAALEDKNSLLREVESAKKQLEETQHD 496
Query: 329 LTSRVEALQPVQLELHEAKVKLSSV 353
V ++ ++ EL +++ +S+
Sbjct: 497 KDQLVLNIEALRAELDHMRLRGASL 521
Score = 33.5 bits (73), Expect = 2.3
Identities = 31/164 (18%), Positives = 73/164 (44%), Gaps = 5/164 (3%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
+ ++ E S ++E+++D+D + L ++ L++++ + ++ E + L
Sbjct: 266 QSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTL 325
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
EK+ Q+ + + +L + ++ + +K + R + + RL E+ L+
Sbjct: 326 EKRYLAAQREATSVHDLNDKLEN----EIANKDSMHRQTEDKNRQLQ-ERLELAEQKLQQ 380
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ L E +L RV AL + + +L +E+QLE
Sbjct: 381 TLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLE 424
>U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1a
protein.
Length = 1185
Score = 50.0 bits (114), Expect = 2e-05
Identities = 57/265 (21%), Positives = 113/265 (42%), Gaps = 10/265 (3%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS-DME 149
E ++K L + + +T+LE ++ T RK++ + EE + +++ R+ A DME
Sbjct: 265 EQSQMKERLASLSSHVTELEEDLD---TARKDL--IKSEEMNTKLQRDVREAMAQKEDME 319
Query: 150 DXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQI 209
+ + E T+ + D N K +H+Q D K++ L+ + +Q
Sbjct: 320 ERITTLEKRYLAAQREA-TSVHDLNDKLENEIANKDSMHRQTED-KNRQLQERLELAEQK 377
Query: 210 SEMKKDMDELLQALEGAQSE-VEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKL 268
+ E L +E ++ V L K + + E+ Q++ QLE++N E Q+ +
Sbjct: 378 LQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQRE 437
Query: 269 KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQ 328
K E D + + + L++ + L LR+ K LEE H
Sbjct: 438 KMNEEHNKRLSDTVDKLLSESNERLQL-HLKERMAALEDKNSLLREVESAKKQLEETQHD 496
Query: 329 LTSRVEALQPVQLELHEAKVKLSSV 353
V ++ ++ EL +++ +S+
Sbjct: 497 KDQLVLNIEALRAELDHMRLRGASL 521
Score = 33.5 bits (73), Expect = 2.3
Identities = 31/164 (18%), Positives = 73/164 (44%), Gaps = 5/164 (3%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQL 254
+ ++ E S ++E+++D+D + L ++ L++++ + ++ E + L
Sbjct: 266 QSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTL 325
Query: 255 EKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRD 314
EK+ Q+ + + +L + ++ + +K + R + + RL E+ L+
Sbjct: 326 EKRYLAAQREATSVHDLNDKLEN----EIANKDSMHRQTEDKNRQLQ-ERLELAEQKLQQ 380
Query: 315 AICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
+ L E +L RV AL + + +L +E+QLE
Sbjct: 381 TLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLE 424
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/406 (19%), Positives = 169/406 (41%), Gaps = 35/406 (8%)
Query: 223 LEGAQSEVEM--LKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLK-ELEYERDSYK 279
L+ A++E EM +K+E K + + +LE++ + + L+ +++ E DS
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQ- 337
D + + + K + KEVT E + + K LE++ +L ++ L+
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 338 ---PVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXX 394
V+ + H + K+ ++ ++ + A + AL++ + L
Sbjct: 963 TLAKVEKQKHATENKVKNLTEEMAG-LDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 395 XXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQ 454
L ++V L+ ++ DL ++ E + Q+ + + ++ +
Sbjct: 1022 ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDE 1081
Query: 455 QLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
+L+ E E++ + E +V + QL+K + ++L A +E L
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEI------QLQKKI---KELQAR---------IEELGE 1123
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKV-LHLTNNPAAEAQKQISKELE 573
E+ R A + + L + + ++ LE G T + L AE QK + ++LE
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQK-LRRDLE 1182
Query: 574 AAQEEIKKLKVALREGGAQADPE------ELQQMRQQLENSRIKLK 613
A + + + ALR+ A + E LQ+++Q+LE + +LK
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Score = 48.4 bits (110), Expect = 7e-05
Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 163 KDEFNTAAKEHKDLKANWD---KEKTDLHKQIADLKDKLLEAN------VSNKDQISEMK 213
KDE + + K+L+ KEK DL Q+ D L +A + NK Q+
Sbjct: 863 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922
Query: 214 KDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ-CTQLKNQLEKQNFEFQQVTSKLKELE 272
K++ E + E +E+ K++L + S ++ L+ L K + +K+K L
Sbjct: 923 KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLT 982
Query: 273 YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSR 332
E +T +K ++++ ++ + L+A E + K LE+QV L
Sbjct: 983 EEMAGLD--ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGS 1040
Query: 333 VEALQPVQLELHEAKVKL 350
+E + ++++L AK KL
Sbjct: 1041 LEQEKKLRMDLERAKRKL 1058
Score = 45.6 bits (103), Expect = 5e-04
Identities = 100/523 (19%), Positives = 212/523 (40%), Gaps = 45/523 (8%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E + L +D+ + A L+ + + + E + +EE +A L E +++ R++S
Sbjct: 1427 EVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL-EASQKESRSLST--- 1482
Query: 151 XXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQIS 210
D+ T + HK+L+ +E +DL +QIA+ ++ E K
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRAHKNLQ----QEISDLTEQIAEGGKQIHELEKIKK---- 1534
Query: 211 EMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQC-TQLKNQLEKQNFEFQQVTSKLK 269
+++++ E+ ALE A++ +E + ++++ Q +++ ++ +++ E Q+
Sbjct: 1535 QVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
Query: 270 ELEYERDSYKDWQTQSKTAQKRLCNMAE---LEKEVTRLRANE---RSLRDAICNKLLLE 323
+ S D + +S+ R+ E E E+ AN SLR+ + +L+
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1654
Query: 324 EQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES-WMSAARAHGVESAGA--LRDALE 380
E L + + ++ +L + + + +++++E W + + L DA E
Sbjct: 1655 ETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASE 1714
Query: 381 SAL---GXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHR 437
L EV + E A K T + +
Sbjct: 1715 RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKK 1774
Query: 438 LQKRLLLVTRERDSYRQQLDCYEKELTVT--LCGEEGAGSVALLSARVQQLEKSLQGYRD 495
Q + R + + Q + + L L + G + L ARV++LE ++
Sbjct: 1775 EQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE---- 1830
Query: 496 LIAAHDPHAHSKALESLRNEVTRWRE---EAEGARRDVTKLRTQRDLLTASLERIGPQTK 552
++ +++A++ LR R +E + E R++V +L+ D L A ++ Q +
Sbjct: 1831 ----NEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 553 VLHLTNNPAAEAQKQISKELEAAQE-------EIKKLKVALRE 588
+N +++ ELE A+E ++ KL+V RE
Sbjct: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSRE 1929
Score = 44.8 bits (101), Expect = 0.001
Identities = 80/429 (18%), Positives = 166/429 (38%), Gaps = 28/429 (6%)
Query: 165 EFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDEL---LQ 221
+ A +H+ + A K+ D ++ + D L + + SE+K + D+L +
Sbjct: 1180 DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAE 1239
Query: 222 ALEGAQSEVEMLKKELVKQTS----RAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDS 277
A+ A+ +E + + L Q S + E+ +L N L Q Q + E+D+
Sbjct: 1240 AISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDA 1299
Query: 278 YKDWQTQSKTAQKRLCN--MAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEA 335
++SK A + +LE+E A +L+ + + LL EQ + E
Sbjct: 1300 LVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE---EQEG 1356
Query: 336 LQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXX 395
+Q L +A +++ ++ E+ E+ L L+ A
Sbjct: 1357 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCAS 1416
Query: 396 XXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQ 455
L EV L + +++ L ++N + ++ +++ E ++ +++
Sbjct: 1417 LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKE 1476
Query: 456 LDCYEKEL-TVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRN 514
EL V EE + L + L++ + + IA H LE ++
Sbjct: 1477 SRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHE--LEKIKK 1534
Query: 515 EVTRWREEAEGARRDVTKLRTQRDLLTASLERIGPQTKVLHLTNNPAAEAQKQISKELEA 574
+V + + E + A + ASLE + K+L + + + ++ +++
Sbjct: 1535 QVEQEKCEIQAALEEA----------EASLEH--EEGKILRI-QLELNQVKSEVDRKIAE 1581
Query: 575 AQEEIKKLK 583
EEI +LK
Sbjct: 1582 KDEEIDQLK 1590
Score = 43.2 bits (97), Expect = 0.003
Identities = 64/298 (21%), Positives = 117/298 (39%), Gaps = 18/298 (6%)
Query: 178 ANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKEL 237
A +KE + ++ KD+L ++ K E+++ M LL+ Q +V+ L
Sbjct: 846 AETEKEMATMKEEFQKTKDELAKSEAKRK----ELEEKMVTLLKEKNDLQLQVQSEADSL 901
Query: 238 VKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK-DWQTQSKTAQKRLCNM- 295
R EQ + K QLE + E + + +E+ E + K + + +K + ++
Sbjct: 902 ADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE 961
Query: 296 AELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPV------QLELHEAKVK 349
L K + A E +++ L+E + +L+ +ALQ L+ E KV
Sbjct: 962 LTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 350 -LSSVESQLESWMSAARAHGVESAGALRDALESAL----GXXXXXXXXXXXXXXXXXHLT 404
L+ +++LE + +E LR LE A G L
Sbjct: 1022 ILTKAKTKLEQQVDDLEG-SLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 405 EEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKE 462
E++ ++E K+ D V + I LQ R+ + E ++ R EK+
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 311 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 369
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 370 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 429
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 430 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 486
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 487 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 546
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 547 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 606
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 607 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 659
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 660 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 718
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 719 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 760
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 396 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 455
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 456 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 515
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 516 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 572
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 573 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 632
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 633 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 669
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 320 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 379
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 380 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 430
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 431 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 484
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 485 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 537
Query: 346 AKV 348
KV
Sbjct: 538 GKV 540
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 129 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 185
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 186 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 243
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 244 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 288
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 212 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 270
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 271 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 330
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 331 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 387
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 388 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 447
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 448 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 507
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 508 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 560
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 561 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 619
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 620 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 661
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 297 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 356
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 357 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 416
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 417 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 473
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 474 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 533
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 534 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 570
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 221 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 280
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 281 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 331
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 332 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 385
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 386 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 438
Query: 346 AKV 348
KV
Sbjct: 439 GKV 441
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 30 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 86
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 87 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 144
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 145 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 189
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 311 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 369
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 370 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 429
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 430 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 486
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 487 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 546
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 547 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 606
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 607 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 659
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 660 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 718
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 719 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 760
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 396 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 455
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 456 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 515
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 516 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 572
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 573 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 632
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 633 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 669
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 320 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 379
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 380 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 430
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 431 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 484
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 485 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 537
Query: 346 AKV 348
KV
Sbjct: 538 GKV 540
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 129 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 185
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 186 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 243
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 244 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 288
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 212 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 270
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 271 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 330
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 331 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 387
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 388 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 447
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 448 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 507
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 508 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 560
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 561 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 619
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 620 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 661
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 297 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 356
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 357 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 416
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 417 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 473
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 474 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 533
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 534 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 570
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 221 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 280
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 281 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 331
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 332 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 385
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 386 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 438
Query: 346 AKV 348
KV
Sbjct: 439 GKV 441
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 30 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 86
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 87 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 144
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 145 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 189
>AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens
cDNA FLJ34363 fis, clone FEBRA2015042. ).
Length = 936
Score = 50.0 bits (114), Expect = 2e-05
Identities = 102/500 (20%), Positives = 216/500 (43%), Gaps = 44/500 (8%)
Query: 119 IRKEMQILFEEEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKA 178
++ E+Q++ ++E SL+++ ++ + A++ E+ K+ +HK++++
Sbjct: 185 LKTELQMV-QDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 243
Query: 179 NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+ L +Q +DL +L+A+ Q ++M +++ ++ LE +S V +L
Sbjct: 244 ELAAARERLQQQASDL---VLKASHIGMLQATQMTQEV--TIKDLESEKSRVNERLSQLE 298
Query: 239 KQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAEL 298
++ + TQ ++ +KQ + ++ K+ E + + Y ++ + K Q R L
Sbjct: 299 EERAFLRSKTQSLDEEQKQ--QILELEKKVNEAKRTQQEY--YERELKNLQSR------L 348
Query: 299 EKEVTRL-RANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQL 357
E+EVT+L A+ ++L + + E VH R + + LE K KL+ E +
Sbjct: 349 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKN 408
Query: 358 ESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKA 417
+ V L D L +A +A+L+ +++
Sbjct: 409 QLQQELENLKEV-----LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERL 463
Query: 418 TGKLNDLTTVRKNQESLIHRLQKRLLLVTRERDSYRQQLDCYEKELTVTLCGEEGAGSVA 477
+L DLT ++SL + LL V E + RQQ E T+ EE V
Sbjct: 464 QNEL-DLT-----KDSL-KETKDALLNVEGELEQERQQ-----HEETIAAMKEEEKLKVD 511
Query: 478 LLSARVQ-QLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD-----VT 531
++ ++ + ++L+ + H + +S +++ + ++ + A RD V
Sbjct: 512 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 571
Query: 532 KLRTQRDLLTASLE-RIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVALREG- 589
L Q LL +LE ++ L + ++++++ELE +E ++ +L+E
Sbjct: 572 DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEERHQQRHKSLKEAH 631
Query: 590 --GAQADPEELQQMRQQLEN 607
Q EE ++ ++ LEN
Sbjct: 632 VLAFQTMEEEKEKEQRALEN 651
Score = 44.8 bits (101), Expect = 0.001
Identities = 55/289 (19%), Positives = 126/289 (43%), Gaps = 28/289 (9%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKAS----LIEQHKRDERAVS 146
E ++LK+D +A +I E+ +R+E+++ EE+K S L++ R++ A
Sbjct: 504 EEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR 563
Query: 147 D-----MEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEA 201
D +ED + + + + + L+A + +E+ L +++ +L+++ +
Sbjct: 564 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEERHQQR 623
Query: 202 NVSNKD----QISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ---CTQLKNQL 254
+ S K+ M+++ ++ +ALE + + + +K R +++ +L
Sbjct: 624 HKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 683
Query: 255 EKQNFEFQ-----QVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANE 309
+ FE + + S EL ++ + D + + M ELE+ + +
Sbjct: 684 QTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKM-ELERSID---ISR 739
Query: 310 RSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLE 358
R ++ IC L+E++ + L LHE +S++ +LE
Sbjct: 740 RQSKEHICRITDLQEELRHREHHISELDKEVQHLHE---NISALTKELE 785
Score = 39.9 bits (89), Expect = 0.026
Identities = 61/287 (21%), Positives = 125/287 (43%), Gaps = 34/287 (11%)
Query: 103 KAQITKLESRVNHQHTIRKE--------MQILFEEEKASLIEQHKRDERAVS---DMEDX 151
K QI +LE +VN ++E +Q EEE L E H + ++ M
Sbjct: 316 KQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIE 375
Query: 152 XXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLE-ANVSNKD--Q 208
K + + + +KD K N +++K L +++ +LK+ L + N +N++
Sbjct: 376 AVHSNAIRDKKKLQMDLEEQHNKD-KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGH 434
Query: 209 ISEMKKDMDELLQALEG----AQSEVEMLKKEL-VKQTSRAEQCTQLKN---QLEKQNFE 260
+ +M + ++ L + EG Q E L+ EL + + S E L N +LE++ +
Sbjct: 435 LQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQ 494
Query: 261 FQQVTSKLKELE------YERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL-- 312
++ + +KE E D W + +L L+ E + A + L
Sbjct: 495 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQL 554
Query: 313 --RDAICNKLLLEEQVHQLTSRVEAL-QPVQLELHEAKVKLSSVESQ 356
R+ + +++V L +++ L Q ++++L +++ L +++Q
Sbjct: 555 KDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQ 601
Score = 32.3 bits (70), Expect = 5.3
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query: 190 QIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQ 249
+I DL+++L + ISE+ K++ L + + E+E KE+++ S + Q +
Sbjct: 748 RITDLQEELRH----REHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIR 803
Query: 250 LKNQLEK-----QNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCN 294
L+ EK E Q+ ++LK + ERD Q K K N
Sbjct: 804 LEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIQKKKNDKSPTN 853
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 50.0 bits (114), Expect = 2e-05
Identities = 94/450 (20%), Positives = 194/450 (43%), Gaps = 42/450 (9%)
Query: 183 EKTDLHKQIADLKDKLLEANVSNK-------DQISEMKKDMDELLQALEGAQSEVEMLKK 235
E DL Q++++ D+L A S +++ + K+D+ +LL A EG + + ++
Sbjct: 9 EIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRER 68
Query: 236 ELVK-QTSRAEQCTQLKNQLEKQNFEFQQVTSKLKE-LEYERDSYKDWQTQSKTAQKRLC 293
EL + + E+ + +++K ++ L+E +E + + ++S T+++
Sbjct: 69 ELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQ--- 125
Query: 294 NMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKVKLSSV 353
+ A E V L+ L+ LE +V QL ++E L+ + + E K
Sbjct: 126 DQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGE 182
Query: 354 ESQLESWMSAARAHGVESAGALRDALESALGXXXXXXXXXXXXXXXXXHLTEEVATLKYE 413
QLE + R E+ A R ALE+ L L+E++ +
Sbjct: 183 IRQLEEALVHVRKEEKEAVSA-RRALENEL---EAAQGNLSQTTQEQKQLSEKLKEESEQ 238
Query: 414 RDKATGKLNDLTTVRKNQESLIHRLQKRLL-LVTRERDS---YRQQLDCYEKELTVTLCG 469
+++ N++ R + I +LQK + +V R S + QLD Y+
Sbjct: 239 KEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK--------- 289
Query: 470 EEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKALESLRNEVTRWREEAEGARRD 529
E+ +A + +++ EK+L+ + + A + +E + R ++EA R+
Sbjct: 290 EKNRRELAEMQRQLK--EKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQL 347
Query: 530 VTKLRTQRDL---LTASLERIGPQTKVLHLTNNPAAEAQKQISKELEAAQEEIKKLKVAL 586
+ +T +DL L A +++++ + ++ + ++ +E + +++ +
Sbjct: 348 LE--QTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERISRS- 404
Query: 587 REGGAQADPEELQQ--MRQQLENSRIKLKR 614
RE Q E LQ+ RQ LE +I L+R
Sbjct: 405 REQMEQLRNELLQERAARQDLECDKISLER 434
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/189 (25%), Positives = 92/189 (48%), Gaps = 14/189 (7%)
Query: 181 DKEKTDLHKQIADLKDKLLEANVSNKD--QISEMKKDMDELLQALEGAQSEVEMLKKELV 238
+K + +L + LK+K LEA S ++ + + M+E L+ + AQ E + K++L+
Sbjct: 290 EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEA-LTKRQLL 348
Query: 239 KQTSR-AEQCTQLKNQLEKQNFEF-QQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMA 296
+QT + E + K+ L+ +Q+ K+ +LE E + ++ S +R+
Sbjct: 349 EQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERN---NSDLLTERISRSR 405
Query: 297 ELEKEVTRLRANERSLR-DAICNKLLLEEQVHQLTSRVEALQPVQLELHEAKV-----KL 350
E +++ ER+ R D C+K+ LE Q L SR+ L+ E V ++
Sbjct: 406 EQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARI 465
Query: 351 SSVESQLES 359
+ +E +LES
Sbjct: 466 AELEDRLES 474
Score = 38.7 bits (86), Expect = 0.060
Identities = 64/314 (20%), Positives = 133/314 (42%), Gaps = 21/314 (6%)
Query: 28 DKLSASTNLNFSDSTQSIKEGLSNLLTFGKRKSSIGSVDDVTPDKRLRRDSSGNGTTAPP 87
DKL + +S++E N+ R S+ D + R++ N
Sbjct: 89 DKLKEQYDAELQALRESVEEATKNVEVLASR-SNTSEQDQAGTEMRVKLLQEENEKLQGR 147
Query: 88 SPWETKRLKIDLIAAKAQITKLES-RVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVS 146
S E +R L + QI L+ + T++K + + E+A L+ K ++ AVS
Sbjct: 148 SE-ELERRVAQL---QRQIEDLKGDEAKAKETLKKYEGEIRQLEEA-LVHVRKEEKEAVS 202
Query: 147 DMEDXXXXXXXXXXXXKDEFNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNK 206
+ + +E K L KE+++ +Q+ LK+++
Sbjct: 203 ----ARRALENELEAAQGNLSQTTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLG 257
Query: 207 DQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSR--AEQCTQLKN---QLEKQNFEF 261
I +++K+M ++++A + E++ E ++ R AE QLK + EK
Sbjct: 258 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 317
Query: 262 QQVTSKLKELEYERDSYKDWQTQSKTAQKRL-CNMAELEKEVTRLRANERSLRDAICNKL 320
++ ++ +E E Y+ Q ++ T ++ L + +LE E+ +++ + R + +
Sbjct: 318 MKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYEL-EAKSHLKDDRSRLVKQ- 375
Query: 321 LLEEQVHQLTSRVE 334
+E++V QL +E
Sbjct: 376 -MEDKVSQLEMELE 388
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 311 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 369
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 370 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 429
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 430 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 486
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 487 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 546
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 547 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 606
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 607 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 659
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 660 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 718
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 719 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 760
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 396 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 455
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 456 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 515
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 516 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 572
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 573 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 632
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 633 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 669
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 320 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 379
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 380 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 430
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 431 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 484
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 485 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 537
Query: 346 AKV 348
KV
Sbjct: 538 GKV 540
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 129 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 185
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 186 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 243
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 244 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 288
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 50.0 bits (114), Expect = 2e-05
Identities = 86/462 (18%), Positives = 192/462 (41%), Gaps = 36/462 (7%)
Query: 170 AKEHKDLKA---NWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEGA 226
++EH+++ A N + L ++ L ++ E +NK+ + + ++++ EL +
Sbjct: 238 SQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN-LQKAEEELQELRDKIAKG 296
Query: 227 Q-------SEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYK 279
+ +EVE L+K +++ + E+ T+ ++Q + + Q+ KEL E + +
Sbjct: 297 ECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 356
Query: 280 DWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL-LLEEQVHQLTSRVEA 335
++ + ++ ++ + E T+L N E++L + N+L +++ +V +L
Sbjct: 357 KRMSELEKLEEA---FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 413
Query: 336 LQPVQLELHEAKVKLSSVESQL----ESWMSAARAHGVESAGALRD-ALE--SALGXXXX 388
L+ +L L + KL S L ++ M + + G ++ +E +
Sbjct: 414 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 473
Query: 389 XXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQKRLLLVTRE 448
+ E+V L ERD+ GKL + L+KRL +
Sbjct: 474 LIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV 533
Query: 449 RDSYRQQLDCYEKELTVTLCGEEGAGSVALLSARVQQLEKSLQGYRDLIAAHDPHAHSKA 508
+ ELT C E+ + L+ +++L+K LQ + D
Sbjct: 534 EREITRGRSRKGSELT---CPED--NKIKELTLEIERLKKRLQQLE--VVEGDLMKTEDE 586
Query: 509 LESLRNEVTRWREEAEGARRDVTKLRTQ--RDLLTASLERIGPQTKVLHLTNNPAAEAQK 566
+ L + +++A + + +++ Q ++ E + + ++ H A++ +
Sbjct: 587 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKS-R 645
Query: 567 QISKELEAAQEEIKKLKVALRE-GGAQADPEELQQMRQQLEN 607
+ E++A +E+I +L + Q D LQQ + EN
Sbjct: 646 DLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEEN 687
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/277 (18%), Positives = 131/277 (47%), Gaps = 18/277 (6%)
Query: 98 DLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDE---RAVSDMEDXXXX 154
++ ++Q +L ++ + KE+++ E+ + + E K +E ++ S+
Sbjct: 323 EITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 382
Query: 155 XXXXXXXXKDEFN------TAAKEHKDLKANWDKEKTDLHKQIADLKD---KLLEANVSN 205
KD N + KE + ++ +K + L + LK L++ +
Sbjct: 383 LEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNM 442
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVT 265
++I + ++ +D L + + Q +V + ++L++++ + +LK+++E++ + +
Sbjct: 443 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKL---LKLKSEMEEKVYNLTRER 499
Query: 266 SKL-KELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERS-LRDAICNKLL-L 322
+L +L+ E + + +KRL + E+E+E+TR R+ + S L NK+ L
Sbjct: 500 DELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 559
Query: 323 EEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLES 359
++ +L R++ L+ V+ +L + + + +E + +
Sbjct: 560 TLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 596
Score = 39.9 bits (89), Expect = 0.026
Identities = 55/243 (22%), Positives = 101/243 (41%), Gaps = 24/243 (9%)
Query: 108 KLESRVNHQHTIRKEMQILFE--EEKASLIEQHKRDERAVSDMEDXXXXXXXXXXXXKDE 165
KL ++ +H +R ++ L + EE + ++ E + ++ D E
Sbjct: 247 KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAE 306
Query: 166 FNTAAKEHKDLKANWDKEKTDLHKQIADLKDKLLEANVSNKDQISEMKKDMDELLQALEG 225
K +++ D+E T Q +L+ KL E +K+ E++K L+
Sbjct: 307 VENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEK--------LQK 357
Query: 226 AQSEVEMLKKELVKQTSRAEQCTQLKNQLEKQNFEFQQVTSKLKELEYERDSYKDWQTQS 285
SE+E L++ K S +CTQL LEK E L ELE + K+ +
Sbjct: 358 RMSELEKLEEAFSKSKS---ECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELECSE 411
Query: 286 KTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEEQVHQLTSRVEALQPVQLELHE 345
+K L+ ++T+L++ L D N + E++ Q +V+ L ++ +
Sbjct: 412 SRLEKA---ELSLKDDLTKLKSFTVMLVDERKNMM---EKIKQEERKVDGLNK-NFKVEQ 464
Query: 346 AKV 348
KV
Sbjct: 465 GKV 467
Score = 35.9 bits (79), Expect = 0.43
Identities = 43/166 (25%), Positives = 72/166 (43%), Gaps = 10/166 (6%)
Query: 195 KDKLLEANVSNKDQISEMKKDMDELLQALEGAQSEV--EMLKKELVKQTSRAEQCTQLKN 252
+D +L S + + E K + EL LE Q E ML++ L+ + +L+N
Sbjct: 56 RDAILAQEKSIGEDVYE--KPISEL-DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEN 112
Query: 253 QLEKQNFEFQQVTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSL 312
+ K + LE ER+ K Q K Q R E K + +LR L
Sbjct: 113 EKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR--KEKENAKRLNKLRDELVKL 170
Query: 313 RDAICNKLLLEEQVH--QLTSRVEALQPVQLELHEAKVKLSSVESQ 356
+ + L+ E Q+H QL + + +Q + +L E + KL ++ S+
Sbjct: 171 K-SFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK 215
>AB014555-1|BAA31630.1| 1083|Homo sapiens KIAA0655 protein protein.
Length = 1083
Score = 50.0 bits (114), Expect = 2e-05
Identities = 59/296 (19%), Positives = 135/296 (45%), Gaps = 20/296 (6%)
Query: 91 ETKRLKIDLIAAKAQITKLESRVNHQHTIRKEMQILFEEEKASLIEQHKRDERAVSDMED 150
E+ + +++++ ++ + KLE++ + ++ ++ L + L EQ K+ ++A+ D E
Sbjct: 372 ESLKREVEMLRSELEKIKLEAQ-RYIAQLKSQVNAL----EGELEEQRKQKQKALVDNEQ 426
Query: 151 XXXXXXXXXXXXKD-EFNTAAKEHKDLKANWDKEK----TDLHKQIADLKDKLLEANVSN 205
+ E + +E + KA+ + + + H ++ + +LL N
Sbjct: 427 LRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADT 486
Query: 206 KDQISEMKKDMDELLQALEGAQSEVEMLKKEL-VKQTSRAEQCTQLKNQLEKQNFEFQQV 264
Q++ ++ +E+ + E +VE +K+E +K +++Q +LK +LE + E +
Sbjct: 487 AKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARA 546
Query: 265 TSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRANERSLRDAICNKLLLEE 324
L E + + + +A+K + A ++E L A + +R+ L E
Sbjct: 547 QEALSHTEQSKSELSS-RLDTLSAEKDALSGAVRQREADLLAA-QSLVRET--EAALSRE 602
Query: 325 QVHQLTSRVEALQPVQLELHEAKVKLSSVESQ-LESWMSAARAHGVESAGALRDAL 379
Q Q +S+ + +Q L E + + + + L+ + R E+AG L+DA+
Sbjct: 603 Q--QRSSQEQG--ELQGRLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAV 654
Score = 36.3 bits (80), Expect = 0.32
Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 16/242 (6%)
Query: 212 MKKDMDELLQALEGAQSEVEMLKKELVKQTSRAEQ-CTQLKNQ-------LEKQNFEFQQ 263
+K D D LQ +E + EVEML+ EL K A++ QLK+Q LE+Q + Q+
Sbjct: 363 VKDDRD--LQ-IESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQK 419
Query: 264 VTSKLKELEYERDSYKDWQTQSKTAQKRLCNMAELEKEVTRLRAN---ERSLRDAICNKL 320
++L +E + Q + + +Q L AE + T R N E+ +
Sbjct: 420 ALVDNEQLRHELAQLRAAQLEGERSQ-GLREEAERKASATEARYNKLKEKHSELVHVHAE 478
Query: 321 LLEEQVHQLTSRVEALQPVQLELHEAKVKLSSVESQLESWMSAARAHGVESAGALRDALE 380
LL + ++ Q Q E+ K +L+ Q++ + L+ LE
Sbjct: 479 LLRKNA-DTAKQLTVTQQSQEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELE 537
Query: 381 SALGXXXXXXXXXXXXXXXXXHLTEEVATLKYERDKATGKLNDLTTVRKNQESLIHRLQK 440
+ G L+ + TL E+D +G + +SL+ +
Sbjct: 538 AKAGELARAQEALSHTEQSKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEA 597
Query: 441 RL 442
L
Sbjct: 598 AL 599
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.310 0.125 0.333
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 71,371,374
Number of Sequences: 224733
Number of extensions: 2680641
Number of successful extensions: 23535
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 1782
Number of HSP's that attempted gapping in prelim test: 15460
Number of HSP's gapped (non-prelim): 7483
length of query: 621
length of database: 73,234,838
effective HSP length: 94
effective length of query: 527
effective length of database: 52,109,936
effective search space: 27461936272
effective search space used: 27461936272
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 68 (31.5 bits)
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