Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001882-TA|BGIBMGA001882-PA|IPR013621|Ion transport
N-terminal, IPR005821|Ion transport, IPR000595|Cyclic
nucleotide-binding, IPR003938|EAG/ELK/ERG potassium channel,
IPR002373|cAMP-dependent protein kinase
(620 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 469 e-131
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 469 e-131
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 466 e-131
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 466 e-131
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 466 e-131
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 466 e-131
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 460 e-129
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 460 e-129
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 460 e-129
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 460 e-129
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 453 e-127
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 447 e-125
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 337 6e-92
AC005559-2|AAC33280.2| 528|Homo sapiens hyperpolarization activ... 263 1e-69
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 164 9e-40
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 164 9e-40
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 164 9e-40
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 164 9e-40
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 164 9e-40
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 164 9e-40
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 157 1e-37
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 157 1e-37
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 154 1e-36
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 154 1e-36
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 153 1e-36
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 130 1e-29
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 126 2e-28
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 125 4e-28
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 125 4e-28
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 125 4e-28
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 125 4e-28
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 120 2e-26
AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member... 116 2e-25
U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channe... 115 4e-25
DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated... 115 4e-25
DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium... 115 4e-25
AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b pr... 115 4e-25
AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related p... 115 4e-25
AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K... 115 4e-25
AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein. 115 4e-25
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 113 1e-24
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 113 2e-24
AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein. 109 4e-23
AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subun... 106 2e-22
AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor cGMP... 102 4e-21
BT007336-1|AAP36000.1| 772|Homo sapiens potassium voltage-gated... 96 3e-19
BC001914-1|AAH01914.2| 773|Homo sapiens KCNH2 protein protein. 96 3e-19
AJ609614-1|CAE82156.1| 548|Homo sapiens potassium voltage-gated... 96 3e-19
AB044806-1|BAB19682.1| 888|Homo sapiens HERG-USO protein. 96 3e-19
BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated... 95 9e-19
AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2... 95 9e-19
AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium... 95 9e-19
AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein. 93 2e-18
AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein. 93 2e-18
BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated... 93 4e-18
AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated... 93 4e-18
AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated... 93 4e-18
AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens ... 93 4e-18
AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium... 93 4e-18
AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium... 93 4e-18
AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like pota... 90 2e-17
AB022698-1|BAA83592.1| 1017|Homo sapiens BEC2 protein. 84 1e-15
AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens ... 81 9e-15
AF493798-1|AAM49574.1| 611|Homo sapiens potassium channel splic... 72 5e-12
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 67 2e-10
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 67 2e-10
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 67 2e-10
BC043409-1|AAH43409.1| 422|Homo sapiens KCNH5 protein protein. 66 3e-10
AK074484-1|BAC11016.1| 377|Homo sapiens for mitochondrial prod... 66 3e-10
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 66 5e-10
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 66 5e-10
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 66 5e-10
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 66 5e-10
BC035815-1|AAH35815.1| 732|Homo sapiens potassium voltage-gated... 66 5e-10
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 64 1e-09
BC127673-1|AAI27674.1| 393|Homo sapiens KCNH2 protein protein. 56 3e-07
BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein. 56 5e-07
AY380056-1|AAQ91601.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
AY380049-1|AAQ91594.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
AY380048-1|AAQ91593.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
AY380047-1|AAQ91592.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
AY380046-1|AAQ91591.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
AY380045-1|AAQ91590.1| 84|Homo sapiens potassium channel HERG ... 54 1e-06
BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein. 54 2e-06
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 52 5e-06
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 52 8e-06
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 51 1e-05
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 51 1e-05
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 51 1e-05
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 47 2e-04
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 47 2e-04
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 47 2e-04
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 47 2e-04
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 46 4e-04
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 46 4e-04
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 46 5e-04
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 45 7e-04
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 45 0.001
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 45 0.001
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 45 0.001
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 45 0.001
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 45 0.001
AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated... 42 0.006
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 38 0.14
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 35 0.98
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 35 0.98
BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein. 33 3.0
AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open read... 33 3.0
AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open read... 33 3.0
AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open read... 33 3.0
AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open read... 33 3.0
AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens ... 33 3.0
X65024-1|CAA46158.1| 823|Homo sapiens Xeroderma Pigmentosum Gro... 33 4.0
D21089-1|BAA04651.1| 940|Homo sapiens XP-C repair complementing... 33 4.0
BC016620-1|AAH16620.1| 940|Homo sapiens xeroderma pigmentosum, ... 33 4.0
AY131066-1|AAM77801.1| 940|Homo sapiens xeroderma pigmentosum, ... 33 4.0
AK222844-1|BAD96564.1| 872|Homo sapiens xeroderma pigmentosum, ... 33 4.0
AF261901-1|AAF87574.1| 940|Homo sapiens xeroderma pigmentosum g... 33 4.0
BC117328-1|AAI17329.1| 436|Homo sapiens cyclic nucleotide bindi... 32 6.9
BC117326-1|AAI17327.1| 436|Homo sapiens cyclic nucleotide bindi... 32 6.9
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 32 6.9
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 32 6.9
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 32 6.9
AK093121-1|BAC04062.1| 436|Homo sapiens protein ( Homo sapiens ... 32 6.9
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 32 6.9
AF450108-1|AAP46289.1| 519|Homo sapiens voltage-gated potassium... 31 9.2
AF348984-1|AAL83911.1| 519|Homo sapiens voltage-gated potassium... 31 9.2
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 469 bits (1156), Expect = e-131
Identities = 216/335 (64%), Positives = 265/335 (79%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RI NLI MMLL+ HW GCLQFLVPMLQ FP + WV+IN +
Sbjct: 399 HQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVN 458
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W +QYS+ALFKAMSHMLCIGYGR P ++D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 459 NSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQ 518
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI +Y+EHRYQGK FDEE ILGELSE LR
Sbjct: 519 SLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLR 578
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+NCR LVAS+P FANAD NFV+ ++TKLR+EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 579 EEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHG 638
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 639 VVS-VLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 697
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 698 MMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSG 732
Score = 105 bits (253), Expect = 4e-22
Identities = 51/124 (41%), Positives = 70/124 (56%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ +T WI FN +SDT FLID+V+NFRTGI+ +DN E +ILDP+ I YL++WF
Sbjct: 285 TFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTE-IILDPQRIKMKYLKSWFM 343
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D ISSIP+DYIFLI ++ Y+ QW
Sbjct: 344 VDFISSIPVDYIFLIVETRIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 401
Query: 137 EEVY 140
EE++
Sbjct: 402 EEIF 405
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 469 bits (1156), Expect = e-131
Identities = 216/335 (64%), Positives = 265/335 (79%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RI NLI MMLL+ HW GCLQFLVPMLQ FP + WV+IN +
Sbjct: 399 HQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVN 458
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W +QYS+ALFKAMSHMLCIGYGR P ++D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 459 NSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQ 518
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI +Y+EHRYQGK FDEE ILGELSE LR
Sbjct: 519 SLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLR 578
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+NCR LVAS+P FANAD NFV+ ++TKLR+EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 579 EEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHG 638
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 639 VVS-VLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 697
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 698 MMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSG 732
Score = 105 bits (253), Expect = 4e-22
Identities = 51/124 (41%), Positives = 70/124 (56%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ +T WI FN +SDT FLID+V+NFRTGI+ +DN E +ILDP+ I YL++WF
Sbjct: 285 TFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTE-IILDPQRIKMKYLKSWFM 343
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D ISSIP+DYIFLI ++ Y+ QW
Sbjct: 344 VDFISSIPVDYIFLIVETRIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 401
Query: 137 EEVY 140
EE++
Sbjct: 402 EEIF 405
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 466 bits (1150), Expect = e-131
Identities = 214/335 (63%), Positives = 264/335 (78%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS MRI NLI MMLL+ HW GCLQFLVPMLQ FP N WV+IN +
Sbjct: 348 HQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVN 407
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W E YS+ALFKAMSHMLCIGYGR P+S+TD+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 408 HSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQ 467
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQ+I +Y+EHRYQGK FDE+ ILGEL+ LR
Sbjct: 468 SLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLR 527
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E+++N+NCR LVAS+P FANAD NFV+ ++TKL++EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 528 EEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHG 587
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G LSDGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 588 VVS-VLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 646
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 647 MMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSG 681
Score = 108 bits (260), Expect = 5e-23
Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ + WI FN +SDT FL+D+V+NFRTGI+ +DN E +ILDP+ I K YLRTWF
Sbjct: 234 TFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTE-IILDPEKIKKKYLRTWFV 292
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D +SSIP+DYIFLI + ++ Y+ QW
Sbjct: 293 VDFVSSIPVDYIFLIVEKGIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 350
Query: 137 EEVY 140
EE++
Sbjct: 351 EEIF 354
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 466 bits (1150), Expect = e-131
Identities = 214/335 (63%), Positives = 264/335 (78%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS MRI NLI MMLL+ HW GCLQFLVPMLQ FP N WV+IN +
Sbjct: 348 HQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVN 407
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W E YS+ALFKAMSHMLCIGYGR P+S+TD+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 408 HSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQ 467
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQ+I +Y+EHRYQGK FDE+ ILGEL+ LR
Sbjct: 468 SLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLR 527
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E+++N+NCR LVAS+P FANAD NFV+ ++TKL++EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 528 EEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHG 587
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G LSDGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 588 VVS-VLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 646
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 647 MMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSG 681
Score = 108 bits (260), Expect = 5e-23
Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ + WI FN +SDT FL+D+V+NFRTGI+ +DN E +ILDP+ I K YLRTWF
Sbjct: 234 TFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTE-IILDPEKIKKKYLRTWFV 292
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D +SSIP+DYIFLI + ++ Y+ QW
Sbjct: 293 VDFVSSIPVDYIFLIVEKGIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 350
Query: 137 EEVY 140
EE++
Sbjct: 351 EEIF 354
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 466 bits (1150), Expect = e-131
Identities = 214/335 (63%), Positives = 264/335 (78%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS MRI NLI MMLL+ HW GCLQFLVPMLQ FP N WV+IN +
Sbjct: 348 HQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVN 407
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W E YS+ALFKAMSHMLCIGYGR P+S+TD+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 408 HSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQ 467
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQ+I +Y+EHRYQGK FDE+ ILGEL+ LR
Sbjct: 468 SLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLR 527
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E+++N+NCR LVAS+P FANAD NFV+ ++TKL++EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 528 EEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHG 587
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G LSDGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 588 VVS-VLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 646
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 647 MMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSG 681
Score = 108 bits (260), Expect = 5e-23
Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ + WI FN +SDT FL+D+V+NFRTGI+ +DN E +ILDP+ I K YLRTWF
Sbjct: 234 TFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTE-IILDPEKIKKKYLRTWFV 292
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D +SSIP+DYIFLI + ++ Y+ QW
Sbjct: 293 VDFVSSIPVDYIFLIVEKGIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 350
Query: 137 EEVY 140
EE++
Sbjct: 351 EEIF 354
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 466 bits (1150), Expect = e-131
Identities = 214/335 (63%), Positives = 264/335 (78%), Gaps = 1/335 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS MRI NLI MMLL+ HW GCLQFLVPMLQ FP N WV+IN +
Sbjct: 202 HQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVN 261
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W E YS+ALFKAMSHMLCIGYGR P+S+TD+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 262 HSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQ 321
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQ+I +Y+EHRYQGK FDE+ ILGEL+ LR
Sbjct: 322 SLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLR 381
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E+++N+NCR LVAS+P FANAD NFV+ ++TKL++EVFQPGD II+EGTIG KMYFIQ G
Sbjct: 382 EEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHG 441
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+V V+ G LSDGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 442 VVS-VLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 500
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEG 525
+MRR E+VA +RL++IGK +++ H+ + G
Sbjct: 501 MMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSG 535
Score = 105 bits (251), Expect = 6e-22
Identities = 50/124 (40%), Positives = 70/124 (56%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ + WI FN +SDT FL+D+V+NFRTGI+ +DN E +ILDP+ I K YLRTWF
Sbjct: 88 TFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTE-IILDPEKIKKKYLRTWFV 146
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+ +SSIP+DYIFLI + ++ Y+ QW
Sbjct: 147 VVFVSSIPVDYIFLIVEKGIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 204
Query: 137 EEVY 140
EE++
Sbjct: 205 EEIF 208
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 460 bits (1135), Expect = e-129
Identities = 214/337 (63%), Positives = 265/337 (78%), Gaps = 2/337 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVPMLQ FPP+ WV+IN +
Sbjct: 29 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVN 88
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W QYS ALFKAMSHMLCIGYG+ P + D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 89 HSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQ 148
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI EY+EHRYQGK FDEE ILGELSE LR
Sbjct: 149 SLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLR 208
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+ CR LVA +P FA+AD +FV+ V+TKLR+EVFQPGD++++EG++G KMYFIQ G
Sbjct: 209 EEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHG 268
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
++ V+A G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVDHFNAVL+++P
Sbjct: 269 LLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFP 327
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEGNT 527
+MRR E+VA +RL +IGK N + R+ S G++
Sbjct: 328 MMRRAFETVAMDRLLRIGKK-NSILQRKRSEPSPGSS 363
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 460 bits (1135), Expect = e-129
Identities = 214/337 (63%), Positives = 265/337 (78%), Gaps = 2/337 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVPMLQ FPP+ WV+IN +
Sbjct: 232 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVN 291
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W QYS ALFKAMSHMLCIGYG+ P + D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 292 HSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQ 351
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI EY+EHRYQGK FDEE ILGELSE LR
Sbjct: 352 SLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLR 411
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+ CR LVA +P FA+AD +FV+ V+TKLR+EVFQPGD++++EG++G KMYFIQ G
Sbjct: 412 EEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHG 471
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
++ V+A G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVDHFNAVL+++P
Sbjct: 472 LLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFP 530
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEGNT 527
+MRR E+VA +RL +IGK N + R+ S G++
Sbjct: 531 MMRRAFETVAMDRLLRIGKK-NSILQRKRSEPSPGSS 566
Score = 105 bits (251), Expect = 6e-22
Identities = 49/124 (39%), Positives = 71/124 (57%), Gaps = 1/124 (0%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF ++ S WI FN LSDT FL+D+V+NFRTGI+ ++ AE ++L P+ I YLRTWF
Sbjct: 116 TFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFL 174
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+DLISSIP+DYIFL+ + + ++ Y+ QW
Sbjct: 175 VDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 234
Query: 137 EEVY 140
EE++
Sbjct: 235 EEIF 238
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 460 bits (1135), Expect = e-129
Identities = 214/337 (63%), Positives = 265/337 (78%), Gaps = 2/337 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVPMLQ FPP+ WV+IN +
Sbjct: 232 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVN 291
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W QYS ALFKAMSHMLCIGYG+ P + D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 292 HSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQ 351
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI EY+EHRYQGK FDEE ILGELSE LR
Sbjct: 352 SLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLR 411
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+ CR LVA +P FA+AD +FV+ V+TKLR+EVFQPGD++++EG++G KMYFIQ G
Sbjct: 412 EEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHG 471
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
++ V+A G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVDHFNAVL+++P
Sbjct: 472 LLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFP 530
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEGNT 527
+MRR E+VA +RL +IGK N + R+ S G++
Sbjct: 531 MMRRAFETVAMDRLLRIGKK-NSILQRKRSEPSPGSS 566
Score = 105 bits (251), Expect = 6e-22
Identities = 49/124 (39%), Positives = 71/124 (57%), Gaps = 1/124 (0%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF ++ S WI FN LSDT FL+D+V+NFRTGI+ ++ AE ++L P+ I YLRTWF
Sbjct: 116 TFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFL 174
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+DLISSIP+DYIFL+ + + ++ Y+ QW
Sbjct: 175 VDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 234
Query: 137 EEVY 140
EE++
Sbjct: 235 EEIF 238
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 460 bits (1135), Expect = e-129
Identities = 214/337 (63%), Positives = 265/337 (78%), Gaps = 2/337 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVPMLQ FPP+ WV+IN +
Sbjct: 169 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVN 228
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W QYS ALFKAMSHMLCIGYG+ P + D+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 229 HSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQ 288
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQRI EY+EHRYQGK FDEE ILGELSE LR
Sbjct: 289 SLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLR 348
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E++IN+ CR LVA +P FA+AD +FV+ V+TKLR+EVFQPGD++++EG++G KMYFIQ G
Sbjct: 349 EEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHG 408
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
++ V+A G T L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVDHFNAVL+++P
Sbjct: 409 LLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFP 467
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEGNT 527
+MRR E+VA +RL +IGK N + R+ S G++
Sbjct: 468 MMRRAFETVAMDRLLRIGKK-NSILQRKRSEPSPGSS 503
Score = 105 bits (251), Expect = 6e-22
Identities = 49/124 (39%), Positives = 71/124 (57%), Gaps = 1/124 (0%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF ++ S WI FN LSDT FL+D+V+NFRTGI+ ++ AE ++L P+ I YLRTWF
Sbjct: 53 TFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAE-ILLAPRAIRTRYLRTWFL 111
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+DLISSIP+DYIFL+ + + ++ Y+ QW
Sbjct: 112 VDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 171
Query: 137 EEVY 140
EE++
Sbjct: 172 EEIF 175
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 453 bits (1117), Expect = e-127
Identities = 202/327 (61%), Positives = 263/327 (80%), Gaps = 1/327 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVP+LQ FPP+ WV++NE+
Sbjct: 158 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVN 217
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W +QYS+ALFKAMSHMLCIGYG P S++D+W+TMLSMI GATCYA+F+GHAT LIQ
Sbjct: 218 DSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQ 277
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP +MRQ+I +Y+EHRYQGK FDEE IL EL++ LR
Sbjct: 278 SLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLR 337
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
E+++N+NCR LVA++P FANAD NFV+ +++KLR+EVFQPGD II+EG +G KMYFIQ G
Sbjct: 338 EEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHG 397
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ ++ + + L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN VL++YP
Sbjct: 398 VAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYP 456
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHR 517
+MRR E+VA +RL++IGK +++ +
Sbjct: 457 MMRRAFETVAIDRLDRIGKKNSILLQK 483
Score = 104 bits (250), Expect = 8e-22
Identities = 47/124 (37%), Positives = 72/124 (58%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF + +T WI FN SDT+FL+D+++NFRTG + +D++E +ILDPK+I +YL++WF
Sbjct: 44 TFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSE-IILDPKVIKMNYLKSWFV 102
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D ISSIP+DYIFLI + ++ Y+ QW
Sbjct: 103 VDFISSIPVDYIFLIVEKGMDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 160
Query: 137 EEVY 140
EE++
Sbjct: 161 EEIF 164
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 447 bits (1102), Expect = e-125
Identities = 199/327 (60%), Positives = 261/327 (79%), Gaps = 1/327 (0%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS +RIFNLI MMLL+ HW GCLQFLVP+LQ FPP+ WV++NE+
Sbjct: 279 HQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVN 338
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W +QYS+ALFKAMSHMLCIGYG P S++D+W+TMLSMI GATCYA+F+GHAT LIQ
Sbjct: 339 DSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQ 398
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP +MRQ+I +Y+EHRYQGK FDEE IL EL++ LR
Sbjct: 399 SLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILNELNDPLR 458
Query: 371 EDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEG 430
+++N+NCR LVA++P FANAD NFV+ +++KLR+EVFQPGD I++EG +G KMYFIQ G
Sbjct: 459 GEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIVREGAVGKKMYFIQHG 518
Query: 431 IVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ ++ + + L+DGSYFGEICLLT RR ASVRA+TYC L+SLSVD+FN V ++YP
Sbjct: 519 VAGVITKSSK-EMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVPEEYP 577
Query: 491 LMRRTMESVAAERLNKIGKNPNLVAHR 517
+MRR E+VA +RL++IGK +++ +
Sbjct: 578 MMRRAFETVAIDRLDRIGKKNSILLQK 604
Score = 101 bits (242), Expect = 8e-21
Identities = 46/124 (37%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF + +T WI FN SDT+FL+D+++NFRTG + +D++E +ILDPK+I +YL++W
Sbjct: 165 TFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSE-IILDPKVIKMNYLKSWSV 223
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D ISSIP+DYIFLI + ++ Y+ QW
Sbjct: 224 VDFISSIPVDYIFLIVEKGMDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 281
Query: 137 EEVY 140
EE++
Sbjct: 282 EEIF 285
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 337 bits (829), Expect = 6e-92
Identities = 157/240 (65%), Positives = 197/240 (82%), Gaps = 2/240 (0%)
Query: 288 MLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYF 347
MLSMI GATCYA+F+GHAT LIQSLDSSRRQY+EK KQVE+YM++ KLP + RQRI EY+
Sbjct: 5 MLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYY 64
Query: 348 EHRYQGKFFDEEVILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEV 407
EHRYQGK FDEE ILGELSE LRE++IN+ CR LVA +P FA+AD +FV+ V+TKLR+EV
Sbjct: 65 EHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEV 124
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVR 467
FQPGD++++EG++G KMYFIQ G++ V+A G T L+DGSYFGEICLLT RR ASVR
Sbjct: 125 FQPGDLVVREGSVGRKMYFIQHGLLS-VLARGARDTRLTDGSYFGEICLLTRGRRTASVR 183
Query: 468 AETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERLNKIGKNPNLVAHREDDTTSEGNT 527
A+TYC L+SLSVDHFNAVL+++P+MRR E+VA +RL +IGK N + R+ S G++
Sbjct: 184 ADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKK-NSILQRKRSEPSPGSS 242
>AC005559-2|AAC33280.2| 528|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 2
protein.
Length = 528
Score = 263 bits (645), Expect = 1e-69
Identities = 121/181 (66%), Positives = 143/181 (79%)
Query: 191 HTKSNLIFKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQE 250
H + ++AS MRI NLI MMLL+ HW GCLQFLVPMLQ FP N WV+IN +
Sbjct: 348 HQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVN 407
Query: 251 AFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQ 310
W E YS+ALFKAMSHMLCIGYGR P+S+TD+WLTMLSMI GATCYA+F+GHAT LIQ
Sbjct: 408 HSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQ 467
Query: 311 SLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGKFFDEEVILGELSEKLR 370
SLDSSRRQY+EK KQVE+YM++ KLP + RQ+I +Y+EHRYQGK FDE+ ILGEL+ LR
Sbjct: 468 SLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLR 527
Query: 371 E 371
E
Sbjct: 528 E 528
Score = 108 bits (260), Expect = 5e-23
Identities = 51/124 (41%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
+FF D+ + WI FN +SDT FL+D+V+NFRTGI+ +DN E +ILDP+ I K YLRTWF
Sbjct: 234 TFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTE-IILDPEKIKKKYLRTWFV 292
Query: 77 LDLISSIPLDYIFLIFNQDFSENFQILHAGXXXXXXXXXXXXXXXXXXXXXXXXXYVSQW 136
+D +SSIP+DYIFLI + ++ Y+ QW
Sbjct: 293 VDFVSSIPVDYIFLIVEKGIDS--EVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQW 350
Query: 137 EEVY 140
EE++
Sbjct: 351 EEIF 354
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 296 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 354
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 355 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 413
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 414 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 473
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 474 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 532
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 533 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 592
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 593 EAKKALEEKGRQILMK 608
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 203 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 259
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 260 DLAYLKVGTNYPE 272
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 278 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 336
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 337 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 395
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 396 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 455
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 456 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 514
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 515 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 574
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 575 EAKKALEEKGRQILMK 590
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 185 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 241
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 242 DLAYLKVGTNYPE 254
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 296 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 354
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 355 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 413
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 414 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 473
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 474 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 532
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 533 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 592
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 593 EAKKALEEKGRQILMK 608
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 203 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 259
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 260 DLAYLKVGTNYPE 272
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 300 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 358
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 359 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 417
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 418 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 477
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 478 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 536
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 537 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 596
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 597 EAKKALEEKGRQILMK 612
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 207 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 263
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 264 DLAYLKVGTNYPE 276
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 296 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 354
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 355 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 413
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 414 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 473
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 474 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 532
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 533 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 592
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 593 EAKKALEEKGRQILMK 608
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 203 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 259
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 260 DLAYLKVGTNYPE 272
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 164 bits (398), Expect = 9e-40
Identities = 99/316 (31%), Positives = 175/316 (55%), Gaps = 14/316 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSW 259
N ++F RI NL+ +L+I HW+ C+ F + GF +SWV N + E L + Y +
Sbjct: 296 NYPNMF-RIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIY 354
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP + ++ + G +A +G+ ++I ++++SR ++
Sbjct: 355 SLYWSTLTLTTIGETP-PPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEF 413
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ +++YM +RK+ +++ R+ +F++ + K DE+ +L L +KL+ ++ IN +
Sbjct: 414 QAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVH 473
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR VF PGD I K+G IG +MY I EG + +V
Sbjct: 474 LDTL-KKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVAD 532
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L + RR A++R+ Y +LF LS D L +YP
Sbjct: 533 DGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYP 592
Query: 491 LMRRTMESVAAERLNK 506
++ +E + L K
Sbjct: 593 EAKKALEEKGRQILMK 608
Score = 42.3 bits (95), Expect = 0.005
Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 4/73 (5%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + +D ++++D++V RTG ++Q ++ D + +HY T F LD++S +P
Sbjct: 203 WLVLDYSADVLYVLDVLVRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPT 259
Query: 86 DYIFLIFNQDFSE 98
D +L ++ E
Sbjct: 260 DLAYLKVGTNYPE 272
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 157 bits (381), Expect = 1e-37
Identities = 93/318 (29%), Positives = 179/318 (56%), Gaps = 14/318 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVA--INELQEAFWLEQYSW 259
N ++F RI NL+ +++I HW+ C+ + + GF ++WV IN+ + +Y +
Sbjct: 289 NYPNIF-RISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVY 347
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP ++ ++ + G +A +G+ ++I +++++R ++
Sbjct: 348 SLYWSTLTLTTIGETP-PPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEF 406
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ ++ +++YM +R + ++M +R+ ++F++ + K DE+ +L L +KLR ++ IN +
Sbjct: 407 QARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVH 466
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V FA+ ++ + ++V KL+ +V+ PGD I K+G IG +MY I+EG + +V
Sbjct: 467 LDTL-KKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVAD 525
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L RR A++++ Y +LF LS D L +YP
Sbjct: 526 DGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYP 585
Query: 491 LMRRTMESVAAERLNKIG 508
+ +E + L K G
Sbjct: 586 DAKTMLEEKGKQILMKDG 603
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLD 86
W+ + +SD ++LID+ V RTG ++Q + L KLI K+ F LD++S IP D
Sbjct: 196 WLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEEL--KLINKYKSNLQFKLDVLSLIPTD 253
Query: 87 YIFLIFNQDFSE 98
++ ++ E
Sbjct: 254 LLYFKLGWNYPE 265
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 157 bits (381), Expect = 1e-37
Identities = 93/318 (29%), Positives = 179/318 (56%), Gaps = 14/318 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVA--INELQEAFWLEQYSW 259
N ++F RI NL+ +++I HW+ C+ + + GF ++WV IN+ + +Y +
Sbjct: 293 NYPNIF-RISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVY 351
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP ++ ++ + G +A +G+ ++I +++++R ++
Sbjct: 352 SLYWSTLTLTTIGETP-PPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEF 410
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ ++ +++YM +R + ++M +R+ ++F++ + K DE+ +L L +KLR ++ IN +
Sbjct: 411 QARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVH 470
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V FA+ ++ + ++V KL+ +V+ PGD I K+G IG +MY I+EG + +V
Sbjct: 471 LDTL-KKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVAD 529
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGSYFGEI +L RR A++++ Y +LF LS D L +YP
Sbjct: 530 DGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYP 589
Query: 491 LMRRTMESVAAERLNKIG 508
+ +E + L K G
Sbjct: 590 DAKTMLEEKGKQILMKDG 607
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLD 86
W+ + +SD ++LID+ V RTG ++Q + L KLI K+ F LD++S IP D
Sbjct: 200 WLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEEL--KLINKYKSNLQFKLDVLSLIPTD 257
Query: 87 YIFLIFNQDFSE 98
++ ++ E
Sbjct: 258 LLYFKLGWNYPE 269
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 154 bits (373), Expect = 1e-36
Identities = 95/318 (29%), Positives = 170/318 (53%), Gaps = 14/318 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVA--INELQEAFWLEQYSW 259
N ++F RI NL+ +L+I HW+ C+ + + GF ++WV I + + + +Y +
Sbjct: 268 NYPNIF-RISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIY 326
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
L+ + + IG PP + + + G +A +G+ ++I +++++R ++
Sbjct: 327 CLYWSTLTLTTIGETP-PPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEF 385
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ V+ YM +RK+ + M ++ +F++ + K DE IL L KLR ++ IN +
Sbjct: 386 QAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVH 445
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR +VF PGD I ++G IG +MY I+EG + +V
Sbjct: 446 LSTL-KKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVAD 504
Query: 438 NGEVATS-LSDGSYFGEICLLT------NARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G + LS GS FGEI +L RR A++R+ Y +LF LS D + +YP
Sbjct: 505 DGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYP 564
Query: 491 LMRRTMESVAAERLNKIG 508
++ +E E L K G
Sbjct: 565 DAKKVLEERGREILMKEG 582
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 4/64 (6%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRT-WFFLDLISSIPL 85
W+ + +SD +++ D+ + RTG ++Q ++ D K + +Y+ T F LD+ S IP
Sbjct: 175 WLVLDYVSDVVYIADLFIRLRTGFLEQG---LLVKDTKKLRDNYIHTLQFKLDVASIIPT 231
Query: 86 DYIF 89
D I+
Sbjct: 232 DLIY 235
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 154 bits (373), Expect = 1e-36
Identities = 95/318 (29%), Positives = 170/318 (53%), Gaps = 14/318 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVA--INELQEAFWLEQYSW 259
N ++F RI NL+ +L+I HW+ C+ + + GF ++WV I + + + +Y +
Sbjct: 268 NYPNIF-RISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIY 326
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
L+ + + IG PP + + + G +A +G+ ++I +++++R ++
Sbjct: 327 CLYWSTLTLTTIGETP-PPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEF 385
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ K+ V+ YM +RK+ + M ++ +F++ + K DE IL L KLR ++ IN +
Sbjct: 386 QAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVH 445
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V F + ++ + ++V KLR +VF PGD I ++G IG +MY I+EG + +V
Sbjct: 446 LSTL-KKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVAD 504
Query: 438 NGEVATS-LSDGSYFGEICLLT------NARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G + LS GS FGEI +L RR A++R+ Y +LF LS D + +YP
Sbjct: 505 DGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYP 564
Query: 491 LMRRTMESVAAERLNKIG 508
++ +E E L K G
Sbjct: 565 DAKKVLEERGREILMKEG 582
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 4/64 (6%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRT-WFFLDLISSIPL 85
W+ + +SD +++ D+ + RTG ++Q ++ D K + +Y+ T F LD+ S IP
Sbjct: 175 WLVLDYVSDVVYIADLFIRLRTGFLEQG---LLVKDTKKLRDNYIHTLQFKLDVASIIPT 231
Query: 86 DYIF 89
D I+
Sbjct: 232 DLIY 235
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 153 bits (372), Expect = 1e-36
Identities = 92/318 (28%), Positives = 178/318 (55%), Gaps = 14/318 (4%)
Query: 202 NMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVA--INELQEAFWLEQYSW 259
N ++F RI NL+ +++I HW+ C+ + + GF ++WV IN+ + +Y +
Sbjct: 293 NYPNIF-RISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVY 351
Query: 260 ALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQY 319
+L+ + + IG PP ++ ++ + G +A +G+ ++I +++++R ++
Sbjct: 352 SLYWSTLTLTTIGETP-PPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEF 410
Query: 320 REKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV-INYN 377
+ ++ +++YM +R + ++M +R+ ++F++ + K DE+ +L L +KLR ++ IN +
Sbjct: 411 QARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVH 470
Query: 378 CRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA 437
+L V FA+ ++ + ++V KL+ +V+ PGD I K+G IG +MY I+EG + +V
Sbjct: 471 LDTL-KKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVAD 529
Query: 438 NGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+G LSDGS FGEI +L RR A++++ Y +LF LS D L +YP
Sbjct: 530 DGVTQFVVLSDGSTFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYP 589
Query: 491 LMRRTMESVAAERLNKIG 508
+ +E + L K G
Sbjct: 590 DAKTMLEEKGKQILMKDG 607
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLD 86
W+ + +SD ++LID+ V RTG ++Q + L KLI K+ F LD++S IP D
Sbjct: 200 WLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEEL--KLINKYKSNLQFKLDVLSLIPTD 257
Query: 87 YIFLIFNQDFSE 98
++ ++ E
Sbjct: 258 LLYFKLGWNYPE 269
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 130 bits (315), Expect = 1e-29
Identities = 81/263 (30%), Positives = 146/263 (55%), Gaps = 13/263 (4%)
Query: 227 LQFLVPMLQGFPPNSWVAIN-ELQEAFWLEQ-YSWALFKAMSHMLCIGYGRFPPQSLTDM 284
+ F + GF +SWV N + E L + Y ++L+ + + IG PP +
Sbjct: 1 IYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIYSLYWSTLTLTTIGETP-PPVKDEEY 59
Query: 285 WLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPREMRQRIT 344
++ + G +A +G+ ++I ++++SR +++ K+ +++YM +RK+ +++ R+
Sbjct: 60 LFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVI 119
Query: 345 EYFEHRYQGK-FFDEEVILGELSEKLREDV-INYNCRSLVASVPFFANADSNFVSDVVTK 402
+F++ + K DE+ +L L +KL+ ++ IN + +L V F + ++ + ++V K
Sbjct: 120 RWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTL-KKVRIFQDCEAGLLVELVLK 178
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVA-TSLSDGSYFGEICLL---- 457
LR VF PGD I K+G IG +MY I EG + +V +G LSDGSYFGEI +L
Sbjct: 179 LRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKG 238
Query: 458 --TNARRVASVRAETYCNLFSLS 478
+ RR A++R+ Y +LF LS
Sbjct: 239 SKSGNRRTANIRSIGYSDLFCLS 261
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 126 bits (304), Expect = 2e-28
Identities = 75/254 (29%), Positives = 147/254 (57%), Gaps = 13/254 (5%)
Query: 236 GFPPNSWVA--INELQEAFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMIS 293
GF ++WV IN+ + +Y ++L+ + + IG PP ++ ++ +
Sbjct: 10 GFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETP-PPVRDSEYVFVVVDFLI 68
Query: 294 GATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQG 353
G +A +G+ ++I +++++R +++ ++ +++YM +R + ++M +R+ ++F++ +
Sbjct: 69 GVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTN 128
Query: 354 K-FFDEEVILGELSEKLREDV-INYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPG 411
K DE+ +L L +KLR ++ IN + +L V FA+ ++ + ++V KL+ +V+ PG
Sbjct: 129 KKTVDEKEVLKYLPDKLRAEIAINVHLDTL-KKVRIFADCEAGLLVELVLKLQPQVYSPG 187
Query: 412 DIIIKEGTIGNKMYFIQEGIVDIVMANGEVA-TSLSDGSYFGEICLL------TNARRVA 464
D I K+G IG +MY I+EG + +V +G LSDGSYFGEI +L RR A
Sbjct: 188 DYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTA 247
Query: 465 SVRAETYCNLFSLS 478
++++ Y +LF LS
Sbjct: 248 NIKSIGYSDLFCLS 261
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 125 bits (302), Expect = 4e-28
Identities = 86/318 (27%), Positives = 154/318 (48%), Gaps = 20/318 (6%)
Query: 201 LNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWA 260
L+ A V+ R+ +L H + CL + QG WV Y
Sbjct: 783 LSKAYVY-RVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGNS------YIRC 835
Query: 261 LFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYR 320
+ A+ ++ IG G P++L ++ +L+ +G +++ +G +++ + + + YR
Sbjct: 836 YYFAVKTLITIG-GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYR 894
Query: 321 EKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV---INY 376
+ +YM + K+P+ ++ R+ ++E+ + + DE ++ +L +K+R D+ +NY
Sbjct: 895 SCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNY 954
Query: 377 NCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM 436
N +V+ V F D + D++ +LR V+ P D + K+G IG +MY IQ G V ++
Sbjct: 955 N---IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG 1011
Query: 437 A-NGE-VATSLSDGSYFGEICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPL 491
+G+ V +L GS FGEI LL RR A+V A + NLF L N +L YP
Sbjct: 1012 GPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1071
Query: 492 MRRTMESVAAERLNKIGK 509
++ + A L K
Sbjct: 1072 SQKLLRKKARRMLRSNNK 1089
Score = 41.1 bits (92), Expect = 0.011
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF-LDLISSIPL 85
W+ + L D I+ +DI V F+T + Q +I D K + +YL++ F +DL+S +PL
Sbjct: 691 WLLMDYLCDLIYFLDITV-FQTRL-QFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPL 748
Query: 86 DYIFL 90
D+++L
Sbjct: 749 DFLYL 753
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 125 bits (302), Expect = 4e-28
Identities = 86/318 (27%), Positives = 154/318 (48%), Gaps = 20/318 (6%)
Query: 201 LNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWA 260
L+ A V+ R+ +L H + CL + QG WV Y
Sbjct: 155 LSKAYVY-RVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGNS------YIRC 207
Query: 261 LFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYR 320
+ A+ ++ IG G P++L ++ +L+ +G +++ +G +++ + + + YR
Sbjct: 208 YYFAVKTLITIG-GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYR 266
Query: 321 EKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV---INY 376
+ +YM + K+P+ ++ R+ ++E+ + + DE ++ +L +K+R D+ +NY
Sbjct: 267 SCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNY 326
Query: 377 NCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM 436
N +V+ V F D + D++ +LR V+ P D + K+G IG +MY IQ G V ++
Sbjct: 327 N---IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG 383
Query: 437 A-NGE-VATSLSDGSYFGEICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPL 491
+G+ V +L GS FGEI LL RR A+V A + NLF L N +L YP
Sbjct: 384 GPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPE 443
Query: 492 MRRTMESVAAERLNKIGK 509
++ + A L K
Sbjct: 444 SQKLLRKKARRMLRSNNK 461
Score = 41.1 bits (92), Expect = 0.011
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF-LDLISSIPL 85
W+ + L D I+ +DI V F+T + Q +I D K + +YL++ F +DL+S +PL
Sbjct: 63 WLLMDYLCDLIYFLDITV-FQTRL-QFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPL 120
Query: 86 DYIFL 90
D+++L
Sbjct: 121 DFLYL 125
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 125 bits (302), Expect = 4e-28
Identities = 86/318 (27%), Positives = 154/318 (48%), Gaps = 20/318 (6%)
Query: 201 LNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWA 260
L+ A V+ R+ +L H + CL + QG WV Y
Sbjct: 441 LSKAYVY-RVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGNS------YIRC 493
Query: 261 LFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYR 320
+ A+ ++ IG G P++L ++ +L+ +G +++ +G +++ + + + YR
Sbjct: 494 YYFAVKTLITIG-GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYR 552
Query: 321 EKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV---INY 376
+ +YM + K+P+ ++ R+ ++E+ + + DE ++ +L +K+R D+ +NY
Sbjct: 553 SCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNY 612
Query: 377 NCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM 436
N +V+ V F D + D++ +LR V+ P D + K+G IG +MY IQ G V ++
Sbjct: 613 N---IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG 669
Query: 437 A-NGE-VATSLSDGSYFGEICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPL 491
+G+ V +L GS FGEI LL RR A+V A + NLF L N +L YP
Sbjct: 670 GPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPE 729
Query: 492 MRRTMESVAAERLNKIGK 509
++ + A L K
Sbjct: 730 SQKLLRKKARRMLRSNNK 747
Score = 41.1 bits (92), Expect = 0.011
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF-LDLISSIPL 85
W+ + L D I+ +DI V F+T + Q +I D K + +YL++ F +DL+S +PL
Sbjct: 349 WLLMDYLCDLIYFLDITV-FQTRL-QFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPL 406
Query: 86 DYIFL 90
D+++L
Sbjct: 407 DFLYL 411
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 125 bits (302), Expect = 4e-28
Identities = 86/318 (27%), Positives = 154/318 (48%), Gaps = 20/318 (6%)
Query: 201 LNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWA 260
L+ A V+ R+ +L H + CL + QG WV Y
Sbjct: 777 LSKAYVY-RVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGNS------YIRC 829
Query: 261 LFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYR 320
+ A+ ++ IG G P++L ++ +L+ +G +++ +G +++ + + + YR
Sbjct: 830 YYFAVKTLITIG-GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYR 888
Query: 321 EKVKQVEEYMAYRKLPREMRQRITEYFEHRYQGK-FFDEEVILGELSEKLREDV---INY 376
+ +YM + K+P+ ++ R+ ++E+ + + DE ++ +L +K+R D+ +NY
Sbjct: 889 SCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNY 948
Query: 377 NCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM 436
N +V+ V F D + D++ +LR V+ P D + K+G IG +MY IQ G V ++
Sbjct: 949 N---IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLG 1005
Query: 437 A-NGE-VATSLSDGSYFGEICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPL 491
+G+ V +L GS FGEI LL RR A+V A + NLF L N +L YP
Sbjct: 1006 GPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPE 1065
Query: 492 MRRTMESVAAERLNKIGK 509
++ + A L K
Sbjct: 1066 SQKLLRKKARRMLRSNNK 1083
Score = 41.1 bits (92), Expect = 0.011
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF-LDLISSIPL 85
W+ + L D I+ +DI V F+T + Q +I D K + +YL++ F +DL+S +PL
Sbjct: 685 WLLMDYLCDLIYFLDITV-FQTRL-QFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPL 742
Query: 86 DYIFL 90
D+++L
Sbjct: 743 DFLYL 747
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 120 bits (288), Expect = 2e-26
Identities = 76/254 (29%), Positives = 137/254 (53%), Gaps = 13/254 (5%)
Query: 236 GFPPNSWVA--INELQEAFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMIS 293
GF ++WV I + + + +Y + L+ + + IG PP + + +
Sbjct: 10 GFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETP-PPVKDEEYLFVIFDFLI 68
Query: 294 GATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQG 353
G +A +G+ ++I +++++R +++ K+ V+ YM +RK+ + M ++ +F++ +
Sbjct: 69 GVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTN 128
Query: 354 K-FFDEEVILGELSEKLREDV-INYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPG 411
K DE IL L KLR ++ IN + +L V F + ++ + ++V KLR +VF PG
Sbjct: 129 KKTVDEREILKNLPAKLRAEIAINVHLSTL-KKVRIFHDCEAGLLVELVLKLRPQVFSPG 187
Query: 412 DIIIKEGTIGNKMYFIQEGIVDIVMANGEVATS-LSDGSYFGEICLLT------NARRVA 464
D I ++G IG +MY I+EG + +V +G + LS GS FGEI +L RR A
Sbjct: 188 DYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTA 247
Query: 465 SVRAETYCNLFSLS 478
++R+ Y +LF LS
Sbjct: 248 NIRSLGYSDLFCLS 261
>AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member 2
protein.
Length = 994
Score = 116 bits (280), Expect = 2e-25
Identities = 78/299 (26%), Positives = 140/299 (46%), Gaps = 19/299 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLV-----PMLQ---GFPPNSWVAINELQEAF-------WL 254
+F L+C LI HW C+ + + P L+ G+ + V + +
Sbjct: 401 LFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNGSDPASGPSVQ 460
Query: 255 EQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDS 314
++Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 461 DKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYS 520
Query: 315 SRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDV 373
+Y ++ +V+E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 521 GTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADI 580
Query: 374 INYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVD 433
+ R+L+ P F+ A + + K + PGD ++ G + + +YFI G ++
Sbjct: 581 CLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIE 640
Query: 434 IVMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
I + + V L FGE L + A VRA TYC+L + VLD YP
Sbjct: 641 I-LRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYP 698
Score = 55.6 bits (128), Expect = 5e-07
Identities = 25/69 (36%), Positives = 43/69 (62%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DIV+NFRT + + ++V+ P+ IA HY + WF +D++++IP D LIF
Sbjct: 308 DIMFVVDIVINFRTTYVNTN--DEVVSHPRRIAVHYFKGWFLIDMVAAIPFD--LLIFRT 363
Query: 95 DFSENFQIL 103
E ++
Sbjct: 364 GSDETTTLI 372
>U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channel
subunit protein.
Length = 1159
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 790 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated
channel subfamily H member 2 protein.
Length = 1159
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 790 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium
channel KV11.1 transcript variant 1 protein.
Length = 1159
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 790 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b
protein protein.
Length = 819
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 210 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 269
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 270 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 329
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 330 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 389
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 390 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 449
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 450 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 506
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 120 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 175
Query: 95 DFSENFQIL 103
E +L
Sbjct: 176 GSEELIGLL 184
>AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related
protein protein.
Length = 1133
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 524 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 583
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 584 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 643
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 644 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 703
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 704 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 763
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 764 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 820
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 434 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 489
Query: 95 DFSENFQIL 103
E +L
Sbjct: 490 GSEELIGLL 498
>AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K+
channel protein protein.
Length = 1159
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 790 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein.
Length = 1159
Score = 115 bits (277), Expect = 4e-25
Identities = 79/298 (26%), Positives = 137/298 (45%), Gaps = 18/298 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + VA L FGE L + VRA TYC+L + D VLD YP
Sbjct: 790 LRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 113 bits (273), Expect = 1e-24
Identities = 82/318 (25%), Positives = 150/318 (47%), Gaps = 15/318 (4%)
Query: 209 RIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWALFKAMSHM 268
R+ +L I H + C+ + +G WV E E +L Y WA+ +
Sbjct: 352 RVIRTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGNE--YLRCYYWAV----RTL 405
Query: 269 LCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEE 328
+ IG G PQ+L ++ +L+ SG ++ +G ++I + +++ +R +
Sbjct: 406 ITIG-GLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIA 464
Query: 329 YMAYRKLPREMRQRITEYFEHRYQG-KFFDEEVILGELSEKLREDV-INYNCRSLVASVP 386
YM +P+ +++R+ ++E+ + + DE +L L ++ + I+ N S+++ V
Sbjct: 465 YMNNYSIPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTTVQLALAIDVNF-SIISKVD 523
Query: 387 FFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA--NGEVATS 444
F D+ + D++ +L+ ++ PGD + K+G IG +MY I+ G V ++ +V +
Sbjct: 524 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLVT 583
Query: 445 LSDGSYFGEICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAA 501
L GS FGEI LL RR A+V A + NL +L +L YP R + A
Sbjct: 584 LKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILVHYPDSERILMKKAR 643
Query: 502 ERLNKIGKNPNLVAHRED 519
L + K R+D
Sbjct: 644 VLLKQKAKTAEATPPRKD 661
Score = 38.3 bits (85), Expect = 0.080
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + + D I+L D++ F +Q +I+D + KHY T F LD+ S IP
Sbjct: 253 WLIADIICDIIYLYDML--FIQPRLQFVRGGDIIVDSNELRKHYRTSTKFQLDVASIIPF 310
Query: 86 D--YIFLIFNQDFSEN 99
D Y+F FN F N
Sbjct: 311 DICYLFFGFNPMFRAN 326
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 113 bits (271), Expect = 2e-24
Identities = 66/254 (25%), Positives = 135/254 (53%), Gaps = 7/254 (2%)
Query: 209 RIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAF--WLEQYSWALFKAMS 266
RI L+ + ++ HW+ CL F + GF ++WV + Q F QY ++ + S
Sbjct: 186 RIAKLMLYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQPGFERLRRQYLYSFY--FS 243
Query: 267 HMLCIGYGRFPPQSLTDMWLTMLS-MISGATCYALFLGHATNLIQSLDSSRRQYREKVKQ 325
++ G PP + + +L M+ + +A +G +++I +++++ +
Sbjct: 244 TLILTTVGDTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHAL 303
Query: 326 VEEYMAYRKLPREMRQRITEYFEH-RYQGKFFDEEVILGELSEKLREDVINYNCRSLVAS 384
V++YM + + R++ +R+ ++++H + K +E IL L E+LR +V S ++
Sbjct: 304 VKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLSTLSR 363
Query: 385 VPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATS 444
V F N +++ + ++V KL+ + + PG+ + ++G IG +MY I+EG + +V +G +
Sbjct: 364 VQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGITQYA 423
Query: 445 -LSDGSYFGEICLL 457
L G YFGEI ++
Sbjct: 424 VLGAGLYFGEISII 437
Score = 55.6 bits (128), Expect = 5e-07
Identities = 25/65 (38%), Positives = 42/65 (64%), Gaps = 4/65 (6%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTW-FFLDLISSIPL 85
W+ + SD ++L+D+VV F TG ++Q +++D I+ Y+RTW FFLDL S +P
Sbjct: 87 WLVLDYTSDLLYLLDMVVRFHTGFLEQG---ILVVDKGRISSRYVRTWSFFLDLASLMPT 143
Query: 86 DYIFL 90
D +++
Sbjct: 144 DVVYV 148
>AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein.
Length = 940
Score = 109 bits (261), Expect = 4e-23
Identities = 63/239 (26%), Positives = 119/239 (49%), Gaps = 4/239 (1%)
Query: 255 EQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDS 314
++Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 509 DKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYS 568
Query: 315 SRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRY-QGKFFDEEVILGELSEKLREDV 373
+Y ++ +V+E++ + ++P +RQR+ EYF+H + D ++L E L+ D+
Sbjct: 569 GTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADI 628
Query: 374 INYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVD 433
+ ++L+ + F A + + K + PGD ++ G + +YF+ G ++
Sbjct: 629 CLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIE 688
Query: 434 IVMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
I + + V L FGE+ L + A VRA TYC+L + + VLD YP
Sbjct: 689 I-LKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYP 746
Score = 60.5 bits (140), Expect = 2e-08
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F+IDI++NFRT + Q+ E+V+ DP IA HY + WF +D++++IP D LIF
Sbjct: 356 DIMFIIDILINFRTTYVNQN--EEVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFGS 411
Query: 95 DFSENFQIL 103
E ++
Sbjct: 412 GSDETTTLI 420
>AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens
cDNA FLJ34558 fis, clone KIDNE2001636, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 905
Score = 107 bits (256), Expect = 2e-22
Identities = 62/223 (27%), Positives = 110/223 (49%), Gaps = 4/223 (1%)
Query: 271 IGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYM 330
+G+G P + ++ ++ M+ G+ YA G+ + +IQ L S +Y ++ +V+E++
Sbjct: 424 VGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFI 483
Query: 331 AYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVINYNCRSLVASVPFFA 389
+ ++P +RQR+ EYF+H + D +L E L+ D+ + R+L+ P F+
Sbjct: 484 RFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFS 543
Query: 390 NADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGS 449
A + + K + PGD ++ G + + +YFI G ++I + + V L
Sbjct: 544 GAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEI-LRDDVVVAILGKND 602
Query: 450 YFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
FGE L + A VRA TYC+L + VLD YP
Sbjct: 603 IFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYP 645
Score = 55.6 bits (128), Expect = 5e-07
Identities = 25/69 (36%), Positives = 43/69 (62%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DIV+NFRT + + ++V+ P+ IA HY + WF +D++++IP D LIF
Sbjct: 308 DIMFVVDIVINFRTTYVNTN--DEVVSHPRRIAVHYFKGWFLIDMVAAIPFD--LLIFRT 363
Query: 95 DFSENFQIL 103
E ++
Sbjct: 364 GSDETTTLI 372
>AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subunit
protein.
Length = 1196
Score = 106 bits (255), Expect = 2e-22
Identities = 63/239 (26%), Positives = 117/239 (48%), Gaps = 4/239 (1%)
Query: 255 EQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDS 314
++Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 612 DKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYS 671
Query: 315 SRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRY-QGKFFDEEVILGELSEKLREDV 373
+Y ++ +V+E++ + ++P +RQR+ EYF+H + D ++L E L+ D+
Sbjct: 672 GTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADI 731
Query: 374 INYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVD 433
+ ++L+ + F A + + K + GD ++ G + +YF+ G ++
Sbjct: 732 CLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHALQGDTLVHCGDVLTALYFLSRGSIE 791
Query: 434 IVMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
I N V L FGE+ L + A VRA TYC+L + + VLD YP
Sbjct: 792 I-SKNDMVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYP 849
Score = 60.5 bits (140), Expect = 2e-08
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F+IDI++NFRT + Q+ E+V+ DP IA HY + WF +D++++IP D LIF
Sbjct: 459 DIMFIIDILINFRTTYVNQN--EEVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFGS 514
Query: 95 DFSENFQIL 103
E ++
Sbjct: 515 GSDETTTLI 523
>AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor
cGMP-gated cation channel beta-subunit protein.
Length = 610
Score = 102 bits (244), Expect = 4e-21
Identities = 76/315 (24%), Positives = 144/315 (45%), Gaps = 14/315 (4%)
Query: 209 RIFNLICMMLLIGHWSGCLQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWALFKAMSHM 268
R+ +L I H + C+ + +G WV E E +L Y WA+ +
Sbjct: 158 RVIRTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGNE--YLRCYYWAV----RTL 211
Query: 269 LCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEE 328
+ IG G PQ+L ++ +L+ SG ++ +G ++I + +++ +R +
Sbjct: 212 ITIG-GLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIA 270
Query: 329 YMAYRKLPREMRQRITEYFEHRYQG-KFFDEEVILGELSEKLREDV-INYNCRSLVASVP 386
YM +P+ +++R+ ++E+ + + DE +L L ++ + I+ N S+++ V
Sbjct: 271 YMNNYSIPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTTVQLALAIDVNF-SIISKVD 329
Query: 387 FFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLS 446
F D+ + D++ +L+ ++ PGD + K+G IG +MY I+ G V ++ G T +
Sbjct: 330 LFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVL--GGPDGTKVL 387
Query: 447 DGSYFGEICLLTNA--RRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERL 504
G + L RR A+V A + NL +L +L YP R + A L
Sbjct: 388 VTLKAGSVLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILVHYPDSERILMKKARVLL 447
Query: 505 NKIGKNPNLVAHRED 519
+ K R+D
Sbjct: 448 KQKAKTAEATPPRKD 462
Score = 38.3 bits (85), Expect = 0.080
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 27 WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPL 85
W+ + + D I+L D++ F +Q +I+D + KHY T F LD+ S IP
Sbjct: 59 WLIADIICDIIYLYDML--FIQPRLQFVRGGDIIVDSNELRKHYRTSTKFQLDVASIIPF 116
Query: 86 D--YIFLIFNQDFSEN 99
D Y+F FN F N
Sbjct: 117 DICYLFFGFNPMFRAN 132
>BT007336-1|AAP36000.1| 772|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 2 protein.
Length = 772
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/248 (24%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 434 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 493
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 494 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 553
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 554 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 613
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 614 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 673
Query: 435 VMANGEVA 442
+ + VA
Sbjct: 674 LRGDVVVA 681
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 344 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 399
Query: 95 DFSENFQIL 103
E +L
Sbjct: 400 GSEELIGLL 408
>BC001914-1|AAH01914.2| 773|Homo sapiens KCNH2 protein protein.
Length = 773
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/248 (24%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 435 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 494
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 495 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 554
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 555 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 614
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 615 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 674
Query: 435 VMANGEVA 442
+ + VA
Sbjct: 675 LRGDVVVA 682
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 345 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 400
Query: 95 DFSENFQIL 103
E +L
Sbjct: 401 GSEELIGLL 409
>AJ609614-1|CAE82156.1| 548|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 2 protein.
Length = 548
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/248 (24%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 210 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 269
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 270 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 329
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 330 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 389
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 390 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 449
Query: 435 VMANGEVA 442
+ + VA
Sbjct: 450 LRGDVVVA 457
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 120 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 175
Query: 95 DFSENFQIL 103
E +L
Sbjct: 176 GSEELIGLL 184
>AB044806-1|BAB19682.1| 888|Homo sapiens HERG-USO protein.
Length = 888
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/248 (24%), Positives = 116/248 (46%), Gaps = 15/248 (6%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 550 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 609
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 610 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 669
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVI 374
+Y ++ +V E++ + ++P +RQR+ EYF+H + D +L E L+ D+
Sbjct: 670 TARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADIC 729
Query: 375 NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDI 434
+ RSL+ F A + + K + PGD ++ G + +YFI G ++I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 435 VMANGEVA 442
+ + VA
Sbjct: 790 LRGDVVVA 797
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 460 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 515
Query: 95 DFSENFQIL 103
E +L
Sbjct: 516 GSEELIGLL 524
>BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 5 protein.
Length = 988
Score = 94.7 bits (225), Expect = 9e-19
Identities = 58/236 (24%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + IG+G P + + ++ M+ G+ YA G+ T + Q + ++
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANT 478
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + K D E +L + +R D+
Sbjct: 479 NRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICV 538
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 539 HLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVI 598
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG+I T A A+VRA TYC+L + + VLD Y
Sbjct: 599 Q-DDEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFY 653
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 237 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 294
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 295 IDLLSCLPYDIINAFENVD 313
>AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2
protein.
Length = 988
Score = 94.7 bits (225), Expect = 9e-19
Identities = 58/236 (24%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + IG+G P + + ++ M+ G+ YA G+ T + Q + ++
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANT 478
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + K D E +L + +R D+
Sbjct: 479 NRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICV 538
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 539 HLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVI 598
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG+I T A A+VRA TYC+L + + VLD Y
Sbjct: 599 Q-DDEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFY 653
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 237 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 294
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 295 IDLLSCLPYDIINAFENVD 313
>AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium
channel EAG2 protein.
Length = 988
Score = 94.7 bits (225), Expect = 9e-19
Identities = 58/236 (24%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + IG+G P + + ++ M+ G+ YA G+ T + Q + ++
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANT 478
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + K D E +L + +R D+
Sbjct: 479 NRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICV 538
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 539 HLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVI 598
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG+I T A A+VRA TYC+L + + VLD Y
Sbjct: 599 Q-DDEVVAILGKGDVFGDIFWKETTLAHACANVRALTYCDLHIIKREALLKVLDFY 653
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 237 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 294
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 295 IDLLSCLPYDIINAFENVD 313
>AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein.
Length = 1117
Score = 93.5 bits (222), Expect = 2e-18
Identities = 63/239 (26%), Positives = 113/239 (47%), Gaps = 9/239 (3%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ A+S + +G+G + T+ ++ +M+ GA +A+ G+ T +IQ + + R
Sbjct: 486 YITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYARR 545
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
Y + + + +Y+ ++P+ ++QR+ EYF+ + D +L L ++LR D I
Sbjct: 546 FLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELRAD-IA 604
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ V +P F A + + LR PG+ +I +G +YF+ G ++ V
Sbjct: 605 MHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSME-V 663
Query: 436 MANGEVATSLSDGSYFGEICLLTNARRV----ASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ G V L G G C L +V A V+ TYC L L + + L YP
Sbjct: 664 LKGGTVLAILGKGDLIG--CELPRREQVVKANADVKGLTYCVLQCLQLAGLHDSLALYP 720
Score = 56.4 bits (130), Expect = 3e-07
Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYI 88
+ +F++DIV+NFRT + + QV+ PK I HY+ TWF LD+I+++P D +
Sbjct: 303 EVLFILDIVLNFRTTFVSKSG--QVVFAPKSICLHYVTTWFLLDVIAALPFDLL 354
>AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein.
Length = 1083
Score = 93.5 bits (222), Expect = 2e-18
Identities = 63/239 (26%), Positives = 113/239 (47%), Gaps = 9/239 (3%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ A+S + +G+G + T+ ++ +M+ GA +A+ G+ T +IQ + + R
Sbjct: 452 YITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQRMYARR 511
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
Y + + + +Y+ ++P+ ++QR+ EYF+ + D +L L ++LR D I
Sbjct: 512 FLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELRAD-IA 570
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ V +P F A + + LR PG+ +I +G +YF+ G ++ V
Sbjct: 571 MHLHKEVLQLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSME-V 629
Query: 436 MANGEVATSLSDGSYFGEICLLTNARRV----ASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ G V L G G C L +V A V+ TYC L L + + L YP
Sbjct: 630 LKGGTVLAILGKGDLIG--CELPRREQVVKANADVKGLTYCVLQCLQLAGLHDSLALYP 686
Score = 56.4 bits (130), Expect = 3e-07
Identities = 23/54 (42%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYI 88
+ +F++DIV+NFRT + + QV+ PK I HY+ TWF LD+I+++P D +
Sbjct: 269 EVLFILDIVLNFRTTFVSKSG--QVVFAPKSICLHYVTTWFLLDVIAALPFDLL 320
>BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 482
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 483 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 542
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 543 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 602
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 603 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 482
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 483 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 542
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 543 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 602
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 603 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 989
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 450 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 509
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 510 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 569
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 570 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 629
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 630 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 684
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens
potassium channel h-eag. ).
Length = 962
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 482
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 483 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 542
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 543 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 602
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 603 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium
channel eagB protein.
Length = 989
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 450 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 509
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 510 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 569
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 570 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 629
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 630 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 684
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium
channel eag protein.
Length = 962
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/236 (23%), Positives = 111/236 (47%), Gaps = 4/236 (1%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + +G+G P + + + M+ G+ YA G+ T + Q + ++
Sbjct: 423 YISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANT 482
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + + D E +L + +R D+
Sbjct: 483 NRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICV 542
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 543 HLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVI 602
Query: 436 MANGEVATSLSDGSYFGEICL--LTNARRVASVRAETYCNLFSLSVDHFNAVLDQY 489
+ EV L G FG++ T A+ A+VRA TYC+L + D VL+ Y
Sbjct: 603 Q-DDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
Score = 67.7 bits (158), Expect = 1e-10
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + A +VI DPKLI +YL+TWF
Sbjct: 240 SFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGP--AGEVISDPKLIRMNYLKTWFV 297
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 298 IDLLSCLPYDVINAFENVD 316
>AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like
potassium channel 1 protein.
Length = 1107
Score = 90.2 bits (214), Expect = 2e-17
Identities = 56/237 (23%), Positives = 113/237 (47%), Gaps = 5/237 (2%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y AL+ +S + +G+G + + ++ +M+ GA +AL G+ T +IQ + S
Sbjct: 421 YIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRW 480
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
Y + K +++++ LP++++QR+ EYF+ + D +L + ++LR D I
Sbjct: 481 SLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSD-IT 539
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ + + F A + + ++ PG+ ++++G +YF+ G ++ V
Sbjct: 540 MHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSME-V 598
Query: 436 MANGEVATSLSDGSYFGEICLLTN--ARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
+ + V L G G + + + A V+A TYC+L + + VLD YP
Sbjct: 599 LKDSMVLAILGKGDLIGANLSIKDQVIKTNADVKALTYCDLQCIILKGLFEVLDLYP 655
Score = 58.8 bits (136), Expect = 5e-08
Identities = 29/72 (40%), Positives = 48/72 (66%), Gaps = 4/72 (5%)
Query: 20 NDDLST-RWIAFNCLS-DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFL 77
NDDLST R + ++ + +F+IDI++NFRT + + QVI + + I HY+ TWF +
Sbjct: 248 NDDLSTTRSTTVSDIAVEILFIIDIILNFRTTYVSKSG--QVIFEARSICIHYVTTWFII 305
Query: 78 DLISSIPLDYIF 89
DLI+++P D ++
Sbjct: 306 DLIAALPFDLLY 317
>AB022698-1|BAA83592.1| 1017|Homo sapiens BEC2 protein.
Length = 1017
Score = 84.2 bits (199), Expect = 1e-15
Identities = 61/247 (24%), Positives = 115/247 (46%), Gaps = 15/247 (6%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y AL+ +S + +G+G + + ++ +M+ GA +A+ G+ T +IQ + S R
Sbjct: 426 YIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRR 485
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
Y ++K +++++ +LPR ++QR+ EYF+ + D +L + ++LR D+
Sbjct: 486 SLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDANELLRDFPDELRADIAM 545
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R ++ +P F A + + ++ PG+ +++ G Y++ G ++++
Sbjct: 546 HLNREIL-QLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRGDALQAHYYVCSGSLEVL 604
Query: 436 MANGEVATSLSDGSYFG--------EICLLTNARRV----ASVRAETYCNLFSLSVDHFN 483
N V L G G E L + V A V+A TYC L LS
Sbjct: 605 RDN-MVLAILGKGDLIGADIPEPGQEPGLGADPNFVLKTSADVKALTYCGLQQLSSRGLA 663
Query: 484 AVLDQYP 490
VL YP
Sbjct: 664 EVLRLYP 670
Score = 62.5 bits (145), Expect = 4e-09
Identities = 28/59 (47%), Positives = 42/59 (71%), Gaps = 3/59 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFN 93
+ +F++DI++NFRT + Q QVI P+ I HYL TWFF+DLI+++P D ++ IFN
Sbjct: 271 EMLFILDIILNFRTTYVSQSG--QVISAPRSIGLHYLATWFFIDLIAALPFDLLY-IFN 326
>AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens
cDNA FLJ33650 fis, clone BRAMY2024514, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 430
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/169 (28%), Positives = 82/169 (48%), Gaps = 4/169 (2%)
Query: 325 QVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVINYNCRSLVA 383
+V+E++ + ++P +RQR+ EYF+H + D +L E L+ D+ + R+L+
Sbjct: 3 RVKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQ 62
Query: 384 SVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVAT 443
P F+ A + + K + PGD ++ G + + +YFI G ++I + + V
Sbjct: 63 HCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEI-LRDDVVVA 121
Query: 444 SLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
L FGE L + A VRA TYC+L + VLD YP
Sbjct: 122 ILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYP 170
>AF493798-1|AAM49574.1| 611|Homo sapiens potassium channel splice
variant HEAG2b protein.
Length = 611
Score = 72.1 bits (169), Expect = 5e-12
Identities = 39/187 (20%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Query: 257 YSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 316
Y +L+ M+ + IG+G P + + ++ M+ G+ YA G+ T + Q + ++
Sbjct: 419 YVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSLLYATIFGNVTTIFQQMYANT 478
Query: 317 RQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRYQ-GKFFDEEVILGELSEKLREDVIN 375
+Y E + V +++ ++P+ + +R+ +Y + K D E +L + +R D+
Sbjct: 479 NRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRADICV 538
Query: 376 YNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIV 435
+ R + P F A + + + + PGD+I G + + F+ G ++++
Sbjct: 539 HLNRKVFNEHPAFRLASDGCLRALAVEFQTIHCAPGDLIYHAGESVDALCFVVSGSLEVI 598
Query: 436 MANGEVA 442
+ VA
Sbjct: 599 QDDEVVA 605
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 237 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 294
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 295 IDLLSCLPYDIINAFENVD 313
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 67.3 bits (157), Expect = 2e-10
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
FA+ D N SD+ + G+ +I++G G+ Y + +G VD+ + NGE T++S+
Sbjct: 137 FAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYV-NGEWVTNISE 195
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 196 GGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKM 244
Score = 40.7 bits (91), Expect = 0.015
Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Query: 399 VVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA---NGEVAT--SLSDGSYFGE 453
V +L F+ G+ I+ +G G+ Y I EG ++ N E L YFGE
Sbjct: 266 VADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGE 325
Query: 454 ICLLTNARRVASVRAETYCNLFSLSVDHFNAVL 486
I LL N R A+V A L F VL
Sbjct: 326 IALLLNRPRAATVVARGPLKCVKLDRPRFERVL 358
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 67.3 bits (157), Expect = 2e-10
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
FA+ D N SD+ + G+ +I++G G+ Y + +G VD+ + NGE T++S+
Sbjct: 138 FAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYV-NGEWVTNISE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 39.9 bits (89), Expect = 0.026
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMA---NGEVAT--SLSDGSYFGEICLLTNARR 462
F+ G+ I+ +G G+ Y I EG ++ N E L YFGEI LL N R
Sbjct: 276 FEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 67.3 bits (157), Expect = 2e-10
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
FA+ D N SD+ + G+ +I++G G+ Y + +G VD+ + NGE T++S+
Sbjct: 138 FAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQGEVDVYV-NGEWVTNISE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 39.9 bits (89), Expect = 0.026
Identities = 28/84 (33%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMA---NGEVAT--SLSDGSYFGEICLLTNARR 462
F+ G+ I+ +G G+ Y I EG ++ N E L YFGEI LL N R
Sbjct: 276 FEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>BC043409-1|AAH43409.1| 422|Homo sapiens KCNH5 protein protein.
Length = 422
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 179 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 236
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 237 IDLLSCLPYDIINAFENVD 255
>AK074484-1|BAC11016.1| 377|Homo sapiens for mitochondrial
product. protein.
Length = 377
Score = 66.5 bits (155), Expect = 3e-10
Identities = 33/79 (41%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 17 SFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFF 76
SF + W+ + + D IFL+DIV+NF T + +VI DPKLI +YL+TWF
Sbjct: 179 SFKTKQNNIAWLVLDSVVDVIFLVDIVLNFHTTFVGPGG--EVISDPKLIRMNYLKTWFV 236
Query: 77 LDLISSIPLDYIFLIFNQD 95
+DL+S +P D I N D
Sbjct: 237 IDLLSCLPYDIINAFENVD 255
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 65.7 bits (153), Expect = 5e-10
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
F++ D N SD+ + F G+ +I++G G+ Y I +G D+ + N E ATS+ +
Sbjct: 138 FSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYV-NNEWATSVGE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 37.9 bits (84), Expect = 0.11
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGE-----VATSLSDGSYFGEICLLTNARR 462
F+ G I+ +G G++ + I EG ++ E L YFGEI LL N R
Sbjct: 276 FEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 65.7 bits (153), Expect = 5e-10
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
F++ D N SD+ + F G+ +I++G G+ Y I +G D+ + N E ATS+ +
Sbjct: 138 FSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYV-NNEWATSVGE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 37.9 bits (84), Expect = 0.11
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGE-----VATSLSDGSYFGEICLLTNARR 462
F+ G I+ +G G++ + I EG ++ E L YFGEI LL N R
Sbjct: 276 FEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 65.7 bits (153), Expect = 5e-10
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
F++ D N SD+ + F G+ +I++G G+ Y I +G D+ + N E ATS+ +
Sbjct: 138 FSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYV-NNEWATSVGE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 37.9 bits (84), Expect = 0.11
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGE-----VATSLSDGSYFGEICLLTNARR 462
F+ G I+ +G G++ + I EG ++ E L YFGEI LL N R
Sbjct: 276 FEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 65.7 bits (153), Expect = 5e-10
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 1/109 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
F++ D N SD+ + F G+ +I++G G+ Y I +G D+ + N E ATS+ +
Sbjct: 138 FSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYV-NNEWATSVGE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTM 496
G FGE+ L+ R A+V+A+T L+ + D + +L L +R M
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKM 245
Score = 37.9 bits (84), Expect = 0.11
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 5/84 (5%)
Query: 408 FQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGE-----VATSLSDGSYFGEICLLTNARR 462
F+ G I+ +G G++ + I EG ++ E L YFGEI LL N R
Sbjct: 276 FEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPR 335
Query: 463 VASVRAETYCNLFSLSVDHFNAVL 486
A+V A L F VL
Sbjct: 336 AATVVARGPLKCVKLDRPRFERVL 359
>BC035815-1|AAH35815.1| 732|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 7 protein.
Length = 732
Score = 65.7 bits (153), Expect = 5e-10
Identities = 27/97 (27%), Positives = 57/97 (58%)
Query: 255 EQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDS 314
++Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 605 DKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYS 664
Query: 315 SRRQYREKVKQVEEYMAYRKLPREMRQRITEYFEHRY 351
+Y ++ +V+E++ + ++P +RQR+ EYF+H +
Sbjct: 665 GTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW 701
Score = 60.5 bits (140), Expect = 2e-08
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F+IDI++NFRT + Q+ E+V+ DP IA HY + WF +D++++IP D LIF
Sbjct: 452 DIMFIIDILINFRTTYVNQN--EEVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFGS 507
Query: 95 DFSENFQIL 103
E ++
Sbjct: 508 GSDETTTLI 516
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 64.5 bits (150), Expect = 1e-09
Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Query: 388 FANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSD 447
F++ D N SD+ + F G+ +I++G G+ Y I +G D+ + N E ATS+ +
Sbjct: 138 FSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYV-NNEWATSVGE 196
Query: 448 GSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQYP 490
G FGE+ L+ R A+V+A+T L+ + D + +L + P
Sbjct: 197 GGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMEDP 239
>BC127673-1|AAI27674.1| 393|Homo sapiens KCNH2 protein protein.
Length = 393
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/146 (23%), Positives = 70/146 (47%), Gaps = 14/146 (9%)
Query: 210 IFNLICMMLLIGHWSGCLQFLVPMLQ--------GFPPNSWVAINELQEAFWL------E 255
+F L+C LI HW C+ + + ++ G+ N I + + L +
Sbjct: 210 LFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKD 269
Query: 256 QYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSS 315
+Y AL+ S + +G+G P + ++ ++ M+ G+ YA G+ + +IQ L S
Sbjct: 270 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSG 329
Query: 316 RRQYREKVKQVEEYMAYRKLPREMRQ 341
+Y ++ +V E++ + ++P +RQ
Sbjct: 330 TARYHTQMLRVREFIRFHQIPNPLRQ 355
Score = 54.8 bits (126), Expect = 9e-07
Identities = 26/69 (37%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 120 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 175
Query: 95 DFSENFQIL 103
E +L
Sbjct: 176 GSEELIGLL 184
>BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein.
Length = 502
Score = 55.6 bits (128), Expect = 5e-07
Identities = 25/69 (36%), Positives = 43/69 (62%), Gaps = 4/69 (5%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DIV+NFRT + + ++V+ P+ IA HY + WF +D++++IP D LIF
Sbjct: 308 DIMFVVDIVINFRTTYVNTN--DEVVSHPRRIAVHYFKGWFLIDMVAAIPFD--LLIFRT 363
Query: 95 DFSENFQIL 103
E ++
Sbjct: 364 GSDETTTLI 372
>AY380056-1|AAQ91601.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>AY380049-1|AAQ91594.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>AY380048-1|AAQ91593.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>AY380047-1|AAQ91592.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>AY380046-1|AAQ91591.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>AY380045-1|AAQ91590.1| 84|Homo sapiens potassium channel HERG
protein.
Length = 84
Score = 54.4 bits (125), Expect = 1e-06
Identities = 25/64 (39%), Positives = 40/64 (62%), Gaps = 4/64 (6%)
Query: 35 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQ 94
D +F++DI++NFRT + + E+V+ P IA HY + WF +D++++IP D LIF
Sbjct: 25 DIMFIVDILINFRTTYVNAN--EEVVSHPGRIAVHYFKGWFLIDMVAAIPFD--LLIFGS 80
Query: 95 DFSE 98
E
Sbjct: 81 GSEE 84
>BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein.
Length = 444
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 3/132 (2%)
Query: 361 ILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTI 420
+L E L+ D+ + RSL+ F A + + K + PGD ++ G +
Sbjct: 1 VLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDL 60
Query: 421 GNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLL--TNARRVASVRAETYCNLFSLS 478
+YFI G ++I+ + VA L FGE L + VRA TYC+L +
Sbjct: 61 LTALYFISRGSIEILRGDVVVAI-LGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIH 119
Query: 479 VDHFNAVLDQYP 490
D VLD YP
Sbjct: 120 RDDLLEVLDMYP 131
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 52.4 bits (120), Expect = 5e-06
Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 11/146 (7%)
Query: 380 SLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA-- 437
S + S+PF + + + VV + +V+ G+ II +G + + ++ G V I M
Sbjct: 269 SFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRK 328
Query: 438 -------NGEVATS-LSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ- 488
NG V + S G YFGE+ L+TN R AS A ++ V F +L
Sbjct: 329 GKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPC 388
Query: 489 YPLMRRTMESVAAERLNKIGKNPNLV 514
+M+R + + + + G N ++V
Sbjct: 389 MEIMKRNIATYEEQLVALFGTNMDIV 414
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 51.6 bits (118), Expect = 8e-06
Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 11/146 (7%)
Query: 380 SLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA-- 437
S + S+PF + + + VV + +V+ G+ II +G + + ++ G V I M
Sbjct: 269 SFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRK 328
Query: 438 -------NGEVATS-LSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ- 488
NG V S G YFGE+ L+TN R AS A ++ V F +L
Sbjct: 329 GKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPC 388
Query: 489 YPLMRRTMESVAAERLNKIGKNPNLV 514
+M+R + + + + G N ++V
Sbjct: 389 MEIMKRNIATYEEQLVALFGTNMDIV 414
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 387 FFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLS 446
F D + D+V + +Q G IIK+G GN ++ + EG +++ ++ +S+
Sbjct: 168 FLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGE-KLLSSIP 226
Query: 447 DGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVL 486
+ FGE+ +L N R ASV+A T ++L + F ++
Sbjct: 227 MWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
Score = 49.2 bits (112), Expect = 4e-05
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 9/135 (6%)
Query: 379 RSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA- 437
R+ + SV N + ++ ++ L E + GD II+EG G+ + + +G V + +
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 438 ----NGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDH--FNAVLDQYPL 491
++ +L G YFGE L+++ R A++ AE ++ L +D FN + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEEN-DVACLVIDRETFNQTVGTFEE 396
Query: 492 MRRTMESVAAERLNK 506
+++ +E A LN+
Sbjct: 397 LQKYLEGYVA-NLNR 410
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 387 FFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLS 446
F D + D+V + +Q G IIK+G GN ++ + EG +++ ++ +S+
Sbjct: 168 FLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGE-KLLSSIP 226
Query: 447 DGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVL 486
+ FGE+ +L N R ASV+A T ++L + F ++
Sbjct: 227 MWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
Score = 49.2 bits (112), Expect = 4e-05
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 9/135 (6%)
Query: 379 RSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA- 437
R+ + SV N + ++ ++ L E + GD II+EG G+ + + +G V + +
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 438 ----NGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDH--FNAVLDQYPL 491
++ +L G YFGE L+++ R A++ AE ++ L +D FN + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEEN-DVACLVIDRETFNQTVGTFEE 396
Query: 492 MRRTMESVAAERLNK 506
+++ +E A LN+
Sbjct: 397 LQKYLEGYVA-NLNR 410
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 51.2 bits (117), Expect = 1e-05
Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 387 FFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLS 446
F D + D+V + +Q G IIK+G GN ++ + EG +++ ++ +S+
Sbjct: 168 FLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGE-KLLSSIP 226
Query: 447 DGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVL 486
+ FGE+ +L N R ASV+A T ++L + F ++
Sbjct: 227 MWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
Score = 49.2 bits (112), Expect = 4e-05
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 9/135 (6%)
Query: 379 RSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMA- 437
R+ + SV N + ++ ++ L E + GD II+EG G+ + + +G V + +
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 438 ----NGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDH--FNAVLDQYPL 491
++ +L G YFGE L+++ R A++ AE ++ L +D FN + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEEN-DVACLVIDRETFNQTVGTFEE 396
Query: 492 MRRTMESVAAERLNK 506
+++ +E A LN+
Sbjct: 397 LQKYLEGYVA-NLNR 410
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V+ V +L +G FG++ L+ +A R AS V E
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + + FN +L
Sbjct: 441 DNCHFLRVDKEDFNRIL 457
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V+ V +L +G FG++ L+ +A R AS V E
Sbjct: 237 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 296
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + + FN +L
Sbjct: 297 DNCHFLRVDKEDFNRIL 313
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V+ V +L +G FG++ L+ +A R AS V E
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + + FN +L
Sbjct: 441 DNCHFLRVDKEDFNRIL 457
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V+ V +L +G FG++ L+ +A R AS V E
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + + FN +L
Sbjct: 441 DNCHFLRVDKEDFNRIL 457
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 46.0 bits (104), Expect = 4e-04
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAET 470
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A++
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 471 Y-CNLFSLSVDHFNAVL 486
Y C+ + FN ++
Sbjct: 288 YNCHFLRVDKQDFNRII 304
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 46.0 bits (104), Expect = 4e-04
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAET 470
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A++
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 471 Y-CNLFSLSVDHFNAVL 486
Y C+ + FN ++
Sbjct: 288 YNCHFLRVDKQDFNRII 304
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 380 SLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM--- 436
S + SVP + + + +V + ++++ G+ II +G + Y I+ G V I++
Sbjct: 254 SFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSR 313
Query: 437 -------ANGEVATS-LSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
N EV + G YFGE+ L+TN R AS A + V F +L
Sbjct: 314 TKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGP 373
Query: 489 -YPLMRRTMESVAAERLNKIGKNPNL 513
+M+R + + + G + +L
Sbjct: 374 CMDIMKRNISHYEEQLVKMFGSSVDL 399
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 45.2 bits (102), Expect = 7e-04
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 413 IIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAETY 471
++ +G G Y I +G V++V+ V +L +G FG++ L+ +A R AS V E
Sbjct: 15 LVFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDN 74
Query: 472 CNLFSLSVDHFNAVL 486
C+ + + FN +L
Sbjct: 75 CHFLRVDKEDFNRIL 89
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A+ + E
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + FN ++
Sbjct: 288 DNCHFLRVDKQDFNRII 304
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A+ + E
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + FN ++
Sbjct: 288 DNCHFLRVDKQDFNRII 304
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A+ + E
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + FN ++
Sbjct: 288 DNCHFLRVDKQDFNRII 304
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A+ + E
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + FN ++
Sbjct: 288 DNCHFLRVDKQDFNRII 304
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 411 GDIIIKEGTIGNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNARRVAS-VRAE 469
G ++ +G G Y I +G V++V + T+L +G FG++ L+ +A R A+ + E
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILRE 287
Query: 470 TYCNLFSLSVDHFNAVL 486
C+ + FN ++
Sbjct: 288 DNCHFLRVDKQDFNRII 304
>AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated
channel, subfamily H, member 8 variant protein.
Length = 583
Score = 41.9 bits (94), Expect = 0.006
Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 4/132 (3%)
Query: 361 ILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTI 420
+L + ++LR D I + + + F A + + ++ PG+ ++++G
Sbjct: 2 LLKDFPDELRSD-ITMHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDA 60
Query: 421 GNKMYFIQEGIVDIVMANGEVATSLSDGSYFGEICLLTNA--RRVASVRAETYCNLFSLS 478
+YF+ G ++ V+ + V L G G + + + A V+A TYC+L +
Sbjct: 61 LQAIYFVCSGSME-VLKDSMVLAILGKGDLIGANLSIKDQVIKTNADVKALTYCDLQCII 119
Query: 479 VDHFNAVLDQYP 490
+ VLD YP
Sbjct: 120 LKGLFEVLDLYP 131
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 37.5 bits (83), Expect = 0.14
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 435 VMANGEVATS-LSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ-YPLM 492
V NG V + S G YFGE+ L+TN R AS A ++ V F +L +M
Sbjct: 27 VEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIM 86
Query: 493 RRTMESVAAERLNKIGKNPNLV 514
+R + + + + G N ++V
Sbjct: 87 KRNIATYEEQLVALFGTNMDIV 108
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 34.7 bits (76), Expect = 0.98
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 12/135 (8%)
Query: 380 SLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANG 439
S + SVP + + + +V + ++++ G+ II + T NK QE V+I +
Sbjct: 254 SFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ-TKSNKDGGNQE--VEIARCH- 309
Query: 440 EVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ-YPLMRRTMES 498
G YFGE+ L+TN R AS A + V F +L +M+R +
Sbjct: 310 -------KGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISH 362
Query: 499 VAAERLNKIGKNPNL 513
+ + G + +L
Sbjct: 363 YEEQLVKMFGSSVDL 377
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 34.7 bits (76), Expect = 0.98
Identities = 34/135 (25%), Positives = 59/135 (43%), Gaps = 12/135 (8%)
Query: 380 SLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVMANG 439
S + SVP + + + +V + ++++ G+ II + T NK QE V+I +
Sbjct: 254 SFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ-TKSNKDGGNQE--VEIARCH- 309
Query: 440 EVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNAVLDQ-YPLMRRTMES 498
G YFGE+ L+TN R AS A + V F +L +M+R +
Sbjct: 310 -------KGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISH 362
Query: 499 VAAERLNKIGKNPNL 513
+ + G + +L
Sbjct: 363 YEEQLVKMFGSSVDL 377
>BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein.
Length = 423
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ32892 fis, clone TESTI2004982, weakly similar to
CGMP-DEPENDENT PROTEIN KINASE 1, ALPHA ISOZYME (EC
2.7.1.37). ).
Length = 572
Score = 33.1 bits (72), Expect = 3.0
Identities = 34/94 (36%), Positives = 42/94 (44%), Gaps = 8/94 (8%)
Query: 403 LRYEVFQPGDIIIKEGTIGNKMYFIQEGIVDIVM-ANGEVA------TSLSDGSYFGEIC 455
+R+E F +IIK+G GN YFI G V I +G A L GS FGE+
Sbjct: 132 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMD 191
Query: 456 LL-TNARRVASVRAETYCNLFSLSVDHFNAVLDQ 488
+L + RR V E L D F LDQ
Sbjct: 192 VLHASVRRSTIVCMEETEFLVVDREDFFANKLDQ 225
>X65024-1|CAA46158.1| 823|Homo sapiens Xeroderma Pigmentosum Group
C Complementing factor protein.
Length = 823
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 214 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 257
>D21089-1|BAA04651.1| 940|Homo sapiens XP-C repair complementing
protein (p125) protein.
Length = 940
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 331 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 374
>BC016620-1|AAH16620.1| 940|Homo sapiens xeroderma pigmentosum,
complementation group C protein.
Length = 940
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 331 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 374
>AY131066-1|AAM77801.1| 940|Homo sapiens xeroderma pigmentosum,
complementation group C protein.
Length = 940
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 331 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 374
>AK222844-1|BAD96564.1| 872|Homo sapiens xeroderma pigmentosum,
complementation group C variant protein.
Length = 872
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 263 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 306
>AF261901-1|AAF87574.1| 940|Homo sapiens xeroderma pigmentosum
group C protein protein.
Length = 940
Score = 32.7 bits (71), Expect = 4.0
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 144 GPQPRDEPADADGSGSRDLFSQILQNLQKKRTERRGRLSSDFAK 187
G +P E AD GS + SQ+L+N K +T + + FAK
Sbjct: 331 GKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK 374
>BC117328-1|AAI17329.1| 436|Homo sapiens cyclic nucleotide binding
domain containing 1 protein.
Length = 436
Score = 31.9 bits (69), Expect = 6.9
Identities = 16/70 (22%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 368 KLREDVI---NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKM 424
K++E+ I N L+ P++ + + +++ L+++ F PG +I++ G I + +
Sbjct: 300 KIKEEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFV 359
Query: 425 YFIQEGIVDI 434
+I G +I
Sbjct: 360 GYINSGCCNI 369
>BC117326-1|AAI17327.1| 436|Homo sapiens cyclic nucleotide binding
domain containing 1 protein.
Length = 436
Score = 31.9 bits (69), Expect = 6.9
Identities = 16/70 (22%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 368 KLREDVI---NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKM 424
K++E+ I N L+ P++ + + +++ L+++ F PG +I++ G I + +
Sbjct: 300 KIKEEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFV 359
Query: 425 YFIQEGIVDI 434
+I G +I
Sbjct: 360 GYINSGCCNI 369
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 31.9 bits (69), Expect = 6.9
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 404 RYEVFQ---PGDIIIKEGTIGNKMYFIQEGIVDIVMANG--------EVATSLSDGSYFG 452
R+ VFQ GD + + G +Y +Q+G++++ + EV S S
Sbjct: 161 RHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLS 220
Query: 453 EICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERLNKI 507
+ ++T + +R S RA + L V+ F+AV +YP + + RL ++
Sbjct: 221 ILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRV 278
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 31.9 bits (69), Expect = 6.9
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 404 RYEVFQ---PGDIIIKEGTIGNKMYFIQEGIVDIVMANG--------EVATSLSDGSYFG 452
R+ VFQ GD + + G +Y +Q+G++++ + EV S S
Sbjct: 161 RHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLS 220
Query: 453 EICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERLNKI 507
+ ++T + +R S RA + L V+ F+AV +YP + + RL ++
Sbjct: 221 ILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRV 278
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 31.9 bits (69), Expect = 6.9
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 404 RYEVFQ---PGDIIIKEGTIGNKMYFIQEGIVDIVMANG--------EVATSLSDGSYFG 452
R+ VFQ GD + + G +Y +Q+G++++ + EV S S
Sbjct: 167 RHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLS 226
Query: 453 EICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERLNKI 507
+ ++T + +R S RA + L V+ F+AV +YP + + RL ++
Sbjct: 227 ILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRV 284
>AK093121-1|BAC04062.1| 436|Homo sapiens protein ( Homo sapiens
cDNA FLJ35802 fis, clone TESTI2005948. ).
Length = 436
Score = 31.9 bits (69), Expect = 6.9
Identities = 16/70 (22%), Positives = 37/70 (52%), Gaps = 3/70 (4%)
Query: 368 KLREDVI---NYNCRSLVASVPFFANADSNFVSDVVTKLRYEVFQPGDIIIKEGTIGNKM 424
K++E+ I N L+ P++ + + +++ L+++ F PG +I++ G I + +
Sbjct: 300 KIKEEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFV 359
Query: 425 YFIQEGIVDI 434
+I G +I
Sbjct: 360 GYINSGCCNI 369
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 31.9 bits (69), Expect = 6.9
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 404 RYEVFQ---PGDIIIKEGTIGNKMYFIQEGIVDIVMANG--------EVATSLSDGSYFG 452
R+ VFQ GD + + G +Y +Q+G++++ + EV S S
Sbjct: 161 RHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSLLS 220
Query: 453 EICLLT---NARRVASVRAETYCNLFSLSVDHFNAVLDQYPLMRRTMESVAAERLNKI 507
+ ++T + +R S RA + L V+ F+AV +YP + + RL ++
Sbjct: 221 ILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQRV 278
>AF450108-1|AAP46289.1| 519|Homo sapiens voltage-gated potassium
channel subunit Kv6.3 protein.
Length = 519
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 227 LQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWL 286
L FL + F P +VA E + + A+ M +GYG P+S+ +
Sbjct: 375 LLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMV 434
Query: 287 TMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVE 327
+ S++SG A AT++ + S + +++ +Q++
Sbjct: 435 ALSSILSGILIMAF---PATSIFHTFSHSYLELKKEQEQLQ 472
>AF348984-1|AAL83911.1| 519|Homo sapiens voltage-gated potassium
channel Kv6.3 protein.
Length = 519
Score = 31.5 bits (68), Expect = 9.2
Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 227 LQFLVPMLQGFPPNSWVAINELQEAFWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWL 286
L FL + F P +VA E + + A+ M +GYG P+S+ +
Sbjct: 375 LLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMV 434
Query: 287 TMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVE 327
+ S++SG A AT++ + S + +++ +Q++
Sbjct: 435 ALSSILSGILIMAF---PATSIFHTFSHSYLELKKEQEQLQ 472
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.136 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,642,406
Number of Sequences: 224733
Number of extensions: 2964810
Number of successful extensions: 7219
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 6774
Number of HSP's gapped (non-prelim): 249
length of query: 620
length of database: 73,234,838
effective HSP length: 94
effective length of query: 526
effective length of database: 52,109,936
effective search space: 27409826336
effective search space used: 27409826336
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 68 (31.5 bits)
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