Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001869-TA|BGIBMGA001869-PA|IPR013602|Dynein heavy chain,
N-terminal region 2, IPR011704|ATPase associated with various cellular
activities, AAA-5, IPR004273|Dynein heavy chain
(3796 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy ch... 1940 0.0
AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein. 1940 0.0
AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dy... 1839 0.0
AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein. 1684 0.0
AK128592-1|BAC87517.1| 1093|Homo sapiens protein ( Homo sapiens ... 1322 0.0
AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein. 1260 0.0
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 1249 0.0
AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein. 1097 0.0
BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein. 1048 0.0
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 1041 0.0
AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein. 1032 0.0
AL096732-1|CAB46377.1| 965|Homo sapiens hypothetical protein pr... 1014 0.0
AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy... 1002 0.0
AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy c... 999 0.0
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c... 997 0.0
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch... 997 0.0
AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1 ... 993 0.0
AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein. 993 0.0
AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy cha... 964 0.0
AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein. 939 0.0
AK023766-1|BAB14671.1| 892|Homo sapiens protein ( Homo sapiens ... 834 0.0
AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein. 725 0.0
AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy... 690 0.0
AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy... 690 0.0
AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy... 690 0.0
AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy... 690 0.0
AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens ... 650 0.0
AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy c... 619 e-176
AC002394-2|AAC05809.1| 573|Homo sapiens Gene product with simil... 609 e-173
BC029567-1|AAH29567.1| 507|Homo sapiens DNAH7 protein protein. 582 e-165
AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein. 576 e-163
BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein pr... 568 e-160
AL117428-1|CAB55917.1| 591|Homo sapiens hypothetical protein pr... 560 e-158
AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, he... 548 e-154
AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein. 548 e-154
AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein, ax... 530 e-149
AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein. 520 e-146
AK097746-1|BAC05158.1| 679|Homo sapiens protein ( Homo sapiens ... 471 e-131
AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens ... 449 e-124
BC128421-1|AAI28422.1| 798|Homo sapiens DNAH9 protein protein. 435 e-120
BC128261-1|AAI28262.1| 798|Homo sapiens DNAH9 protein protein. 435 e-120
X99947-1|CAA68207.1| 798|Homo sapiens dynein-related protein pr... 433 e-120
AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens ... 432 e-119
AK128065-1|BAC87257.1| 821|Homo sapiens protein ( Homo sapiens ... 426 e-118
AK126059-1|BAC86419.1| 933|Homo sapiens protein ( Homo sapiens ... 421 e-116
BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein. 390 e-107
AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens ... 386 e-106
AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein, ax... 303 6e-81
AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain prot... 294 3e-78
AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein. 286 1e-75
AK095579-1|BAC04578.1| 806|Homo sapiens protein ( Homo sapiens ... 264 4e-69
U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heav... 264 6e-69
U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy ... 263 7e-69
AC013274-1|AAY14776.1| 213|Homo sapiens unknown protein. 256 1e-66
U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heav... 254 3e-66
AF015265-1|AAC27542.1| 377|Homo sapiens axonemal dynein protein. 248 4e-64
AK027182-1|BAB15685.1| 366|Homo sapiens protein ( Homo sapiens ... 228 3e-58
AK054657-1|BAB70785.1| 333|Homo sapiens protein ( Homo sapiens ... 224 4e-57
AK026756-1|BAB15543.1| 394|Homo sapiens protein ( Homo sapiens ... 217 6e-55
AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy ... 180 7e-44
AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy ... 178 3e-43
AK021818-1|BAB13905.1| 553|Homo sapiens protein ( Homo sapiens ... 176 1e-42
BC037496-1|AAH37496.1| 504|Homo sapiens DYNC2H1 protein protein. 173 1e-41
Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy cha... 171 6e-41
Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy cha... 167 7e-40
BC021297-1|AAH21297.1| 832|Homo sapiens DYNC1H1 protein protein. 159 2e-37
AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy ... 158 4e-37
Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy cha... 154 5e-36
BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein. 148 3e-34
AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein. 148 3e-34
U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein. 132 3e-29
AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy... 123 1e-26
AK126276-1|BAC86512.1| 457|Homo sapiens protein ( Homo sapiens ... 120 1e-25
U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy cha... 114 7e-24
U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isoty... 108 3e-22
U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy cha... 104 5e-21
U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein. 104 5e-21
AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein. 103 2e-20
U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein. 101 5e-20
Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy ... 96 2e-18
U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein. 91 5e-17
AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens ... 91 5e-17
AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy ... 89 3e-16
U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein. 86 2e-15
AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy ... 82 3e-14
L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein. 81 6e-14
AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy ... 80 1e-13
BC117303-1|AAI17304.1| 1021|Homo sapiens dynein heavy chain doma... 78 7e-13
BC117301-1|AAI17302.1| 1021|Homo sapiens dynein heavy chain doma... 78 7e-13
AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy... 78 7e-13
AK057314-1|BAB71423.1| 1021|Homo sapiens protein ( Homo sapiens ... 78 7e-13
Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy cha... 75 5e-12
U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein. 71 6e-11
U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein. 71 1e-10
U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy cha... 70 2e-10
AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein. 70 2e-10
AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy ... 69 2e-10
Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy cha... 69 4e-10
AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy ... 66 2e-09
Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy cha... 64 9e-09
Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy cha... 62 3e-08
AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein. 57 1e-06
AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy ... 54 1e-05
AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy ... 53 2e-05
AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein pr... 52 5e-05
AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy ... 50 2e-04
U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy cha... 49 3e-04
AK094515-1|BAC04372.1| 501|Homo sapiens protein ( Homo sapiens ... 49 3e-04
U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy cha... 48 9e-04
AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein pr... 46 0.002
AK056509-1|BAE46616.1| 753|Homo sapiens protein ( Homo sapiens ... 46 0.003
D86956-1|BAA13192.2| 949|Homo sapiens KIAA0201 protein. 42 0.057
BC037553-1|AAH37553.1| 858|Homo sapiens heat shock 105kDa/110kD... 42 0.057
AL137142-5|CAI12430.1| 858|Homo sapiens heat shock 105kDa/110kD... 42 0.057
AL137142-4|CAI12428.1| 814|Homo sapiens heat shock 105kDa/110kD... 42 0.057
AL137142-3|CAI12429.1| 817|Homo sapiens heat shock 105kDa/110kD... 42 0.057
AF039695-1|AAC18044.1| 872|Homo sapiens antigen NY-CO-25 protein. 42 0.057
AB003334-1|BAA34780.1| 858|Homo sapiens HSP105 alpha protein. 42 0.057
AB003333-1|BAA34779.1| 814|Homo sapiens HSP105 beta protein. 42 0.057
BC064521-1|AAH64521.1| 197|Homo sapiens DYNC1H1 protein protein. 41 0.10
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 39 0.40
AY028079-1|AAK21976.1| 282|Homo sapiens putative protein protein. 39 0.40
AY027807-1|AAK14796.1| 282|Homo sapiens unknown protein. 39 0.40
AL161645-3|CAH70048.1| 282|Homo sapiens novel protein protein. 39 0.40
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 37 1.6
BC034821-1|AAH34821.1| 315|Homo sapiens SYCE1 protein protein. 36 2.2
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 36 2.2
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 36 2.2
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 36 2.2
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 36 2.2
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 36 2.2
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 36 2.2
X68985-1|CAA48777.1| 295|Homo sapiens hepatic leukemia factor p... 36 3.8
M95585-1|AAA52675.1| 295|Homo sapiens hepatic leukemia factor p... 36 3.8
CR541672-1|CAG46473.1| 295|Homo sapiens HLF protein. 36 3.8
BC036093-1|AAH36093.1| 295|Homo sapiens hepatic leukemia factor... 36 3.8
BC130373-1|AAI30374.1| 633|Homo sapiens ClpX caseinolytic pepti... 35 6.6
AJ276980-1|CAC01291.1| 633|Homo sapiens ClpX protein protein. 35 6.6
AJ006267-1|CAA06933.2| 633|Homo sapiens ClpX-like protein protein. 35 6.6
AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor... 34 8.7
AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor... 34 8.7
AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited g... 34 8.7
>AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy chain 7
protein.
Length = 4024
Score = 1940 bits (4811), Expect = 0.0
Identities = 920/1876 (49%), Positives = 1256/1876 (66%), Gaps = 8/1876 (0%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ T +Y +A +NL PTPAKSHY+FNLRDFSRVIQG L R E+ + + ++W+HE+
Sbjct: 2153 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEV 2212
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQ-DEKGEVNQENIKKMMFGC 2043
+RV+YDRL+D+ DR+W +++ R++M + F + D G V ++++ +MF C
Sbjct: 2213 LRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMF-C 2271
Query: 2044 YLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRIL 2103
E + Y EI + I L EYN++ K M +VLF +A+EH+S+I RIL
Sbjct: 2272 DFHDPKRE-DTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRIL 2330
Query: 2104 SMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGL 2163
P +ALLVGVGGSGRQS+TRLA+ + VFQ EI+K Y +WH+D+K++LR+
Sbjct: 2331 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 2390
Query: 2164 NKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLA--AQGGNRNL 2221
FLFT++QIKEES+++++ +LLN+GE+PNL+ LDEKQEI + +R + +
Sbjct: 2391 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 2450
Query: 2222 DISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALE 2281
D SP+ + F+ C+++LH+VL SPIG +FR RLR +P+LVNCCTIDW+ SWPEDAL+
Sbjct: 2451 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 2510
Query: 2282 MVAHHYMVKVNVPDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSF 2341
VA ++ ++ + + ++ + CK FH +S FF R Y+T SYL+LI +F
Sbjct: 2511 AVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTF 2570
Query: 2342 TTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEI 2401
L +K+ E+ K RY GL++L A+ VA MQ +L AL PQL V +++ +MM I
Sbjct: 2571 KLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMI 2630
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
E E+ K V+ D+ +K +C+ADLA ALPILE A+AAL+TL D
Sbjct: 2631 EKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQD 2690
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLD 2521
IT+VKSMK+PP VKLVM A+C+ + DFWGP+KR+LGDM FL
Sbjct: 2691 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQ 2750
Query: 2522 SLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXX 2581
SL +DKDNIP A M IRK Y+ N DF P + AS AAEGLCKW+IAMD YD
Sbjct: 2751 SLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIV 2810
Query: 2582 XXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCI 2641
M L +K+A + KK LE++V LC
Sbjct: 2811 APKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCS 2870
Query: 2642 DKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII 2701
KL RAE+LIGGLGGEK RW+ A L LY NL GDIL+S G++AYL +T R
Sbjct: 2871 KKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQT 2930
Query: 2702 DKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLL 2761
+W L ++P S+ LG + I+ W IAGLP D FSIDN II N+ RW L+
Sbjct: 2931 KEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLM 2990
Query: 2762 IDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPV 2821
IDPQ QANKWIK MEK N L V+K ++ +Y++ +E C+++G P L++ V E+++ L+P+
Sbjct: 2991 IDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPL 3050
Query: 2822 LLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGL 2881
LLK T+ QGG I LGD+ IEY P+FR Y+TTKLRNPHYLPE KVTL+NF +T +G+
Sbjct: 3051 LLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGM 3110
Query: 2882 EDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIE 2941
+DQ LGIVVA+ERPDL+E+++ LI+QGA N+ LK++ED IL L ++G+ILEDE+AI+
Sbjct: 3111 QDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIK 3170
Query: 2942 VLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYS 3001
+L SSK LA +I +KQE + ETE I+ R+GYRPIA HS++L++ + +L N++PMYQYS
Sbjct: 3171 ILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYS 3230
Query: 3002 LTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKM 3061
LTWFINL+I+SIEN+ KS+ L KRL+ LKD FTY+LY NVCRSLF+KDKL+FSF + +
Sbjct: 3231 LTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINL 3290
Query: 3062 MLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKT 3121
+L +N E++FL+TGGI ++N P WLP K+WDEICRL+DL AF+ R +F++
Sbjct: 3291 LLHERAINKAEWRFLLTGGIGLDNPYANPCTWLPQKSWDEICRLDDLPAFKTIRREFMRL 3350
Query: 3122 IIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYT 3181
W++VYD +EP ++ P W+++ +FQ++L++R LRPDK+ + +F+ +GR +
Sbjct: 3351 KDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFI 3410
Query: 3182 TPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF-SHRFNSISLGQGQGPI 3240
PPPFD++K+FGDSNC APLIF+LSPG+DPM AL+K+ + G+ + +S+SLGQGQGPI
Sbjct: 3411 EPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPI 3470
Query: 3241 ARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQ 3300
A M+EKA EG WV LQNCHLA SW+P LEK+ E +T FR+WLTSYPS FP
Sbjct: 3471 AMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPV 3530
Query: 3301 SVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVV 3360
SVLQ GVKMTNE P GL+ N+ RSY+ +P+ +PEF+ C K + F KLLYG+ FFHA+V
Sbjct: 3531 SVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCK-KPEEFKKLLYGLCFFHALV 3589
Query: 3361 QERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDD 3420
QER+KFGPLGWNI Y FN++D +ISV QL MFLNQYEE+ Y A++Y+TGECNYGGRVTDD
Sbjct: 3590 QERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDD 3649
Query: 3421 WDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVF 3480
WDRR + +IL+ + N +V + +Y F G Y +P +++ Y+++ +++P+ P PE+F
Sbjct: 3650 WDRRTLRSILNKFFNPELVENSDYKFDSSG-IYFVPPSGDHKSYIEYTKTLPLTPAPEIF 3708
Query: 3481 GLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEI 3540
G++ NA IT+D S + L +++L ++ +AS+IL KLP FD+E
Sbjct: 3709 GMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEA 3768
Query: 3541 AQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAML 3600
A ++YP Y +SMNTVL+QEM RFNKLL I+ S ++QKA+KGL VMS L+ +++L
Sbjct: 3769 AMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSIL 3828
Query: 3601 LGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGS 3660
KIPE W SYPSLKPL SYV DF+ RL L+ WY+ G PP FWL GFFFTQAFLTG+
Sbjct: 3829 NVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGA 3888
Query: 3661 VQNYARAKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPK 3720
QNYAR TIPIDLL FD+E+ PP+ GVF+ GLF+DG WNR+ +AE PK
Sbjct: 3889 QQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPK 3948
Query: 3721 VLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPS 3780
+L D +PV+WL P + + + Y PLYKT ER+GVL+TTGHS+NFV+A LPSD+P
Sbjct: 3949 ILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPK 4008
Query: 3781 AHWIKRSVALLLQLDN 3796
HWI R VALL QL++
Sbjct: 4009 EHWIGRGVALLCQLNS 4024
Score = 764 bits (1889), Expect = 0.0
Identities = 455/1315 (34%), Positives = 712/1315 (54%), Gaps = 101/1315 (7%)
Query: 101 PMLKSWERKIRNLIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTVIRDV--PGVPR 158
PM SW + +L+P +L+ F + L +E ++++ ++ V V++D G +
Sbjct: 179 PMEDSWLEHVLDLVPQHLKV-FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDK 237
Query: 159 KRYEEPHFK--FKGVTSNYGK-LLKYRRKLQDGSLLLHPFIRLILESSEKTFP-LHIIDL 214
K E P + + + + K L ++D ++P + +L+ F L ++D+
Sbjct: 238 KTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDI 297
Query: 215 AKYR-AKGPMSLDEFRLKVLDEIKRADYLVSSTWY----GILVQWLKNPRCLKGMKPRKV 269
++ + + L F+ ++ + A + W+ I Q K + G K+
Sbjct: 298 KEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKL 357
Query: 270 NDFVKCATKMISMQIQELMRQSINAIIDFL-KDPEAI-----PVLNVCLDFDGEFI-YDP 322
F CA ++++Q+Q+L S+ D + + P+++ P + L D + I ++P
Sbjct: 358 ESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEP 417
Query: 323 TLETIYEVFHNIADAISHISQRLMPIEQYLKIPYNYDALPVVYNEWLHKDGHERLQQQLN 382
L ++F N+ D + + +E L + + P + + + ++++
Sbjct: 418 ELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIK 477
Query: 383 -IVFKPLNQYVEKLR--QEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDSNI- 438
++ K E LR +Y+ L A+ ++ F+ E ++E++ ++I YQ + I
Sbjct: 478 EVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQ 537
Query: 439 -TAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAAK 497
T++ + C+ ++ L RA ++A + + H N +C EFE IA K
Sbjct: 538 YTSIKTIRLGMFEMHCE-ELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEK 596
Query: 498 ALKEPENATELIEQGVYILHAKTVLVEALKERILVQINIISNLLEMTSLSSDHVKSNTRT 557
AL P N EL+E YI + + L++R++ N ++ L+E + S ++ N
Sbjct: 597 ALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSV 656
Query: 558 VNWLKDIKPIFEKNAAAYETFKADMEESLLGKIAYLNKEVTDMTPYLELLDNMDDVNHTL 617
W + IFE++ + +E L + +E+ E + D+
Sbjct: 657 FQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQ 716
Query: 618 EYLEYLRKLVHRLHDCDKLVTWINNEETTFKFPVTNYPELEELKEFIIPFYSLVYLVHRW 677
YL+ + L +L + N EE F + + YP+ +++++ + P+ L +
Sbjct: 717 RYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEF 776
Query: 678 KRSYYTWMDGPFEYLDHNQIEQDHDFYYKEFLKISKNYRNKIKQQIAEGVEKRFQGLVDD 737
+Y W +GP+ ++ +Q+E D Y++ K+ K + +
Sbjct: 777 SSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDS------------------- 817
Query: 738 PDVNNLPAPMKLCAQAVAEIKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDLTPTAGT 797
P + + + ++++D++ ++ + ++CNP L RHW+ MS I G+ L P+ +
Sbjct: 818 ------PYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS 871
Query: 798 SLRKIINFNLWGDLDQYEIISVAATKELALITNLNKMMAEW------------------- 838
++ ++ NL +D++E IS AA+KE +L + KM+ EW
Sbjct: 872 TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILA 931
Query: 839 ----IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLL 894
IQ +LDDHI+KT MRGS F+KP+E Q+R W K++ + +DEW KVQ+ WLYL
Sbjct: 932 SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 991
Query: 895 PIFSSKDIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLE 954
PIFSS DI++QMPEEG F V+ +R M SV +D HVL + +LE + + LE
Sbjct: 992 PIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1051
Query: 955 KINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGE 1014
I G+N YLEKKRL+FPRFFFLSNDE+LEILSETK+P +VQPHLKKCFEGI ++ F
Sbjct: 1052 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1111
Query: 1015 FNISAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGR 1074
+I+ M S EGE VE +++IS A ARG VEKWLV++E M+ ++ T + + Y R
Sbjct: 1112 LDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYER 1171
Query: 1075 VEWVLSWEGMVVLAISQIYWAVDVHESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLT 1134
+ WV W G VL +SQI+W +V ++ + L+ + +Q+++ V ++ R L+
Sbjct: 1172 INWVRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLV-RGKLS 1229
Query: 1135 KLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEERVYVKIINAVVH 1194
+ +T+ AL+V+DVHA+DV+S L+KK +++ +DF+WL+QLRYYW+E + K+INA +
Sbjct: 1230 MQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLR 1289
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y YEYLGNS RLVITPLTDRCYRTL GA +LHL GAPEGPAGTGKTETTKDLAKA+A QC
Sbjct: 1290 YGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 1349
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAWA---------------VRQHLETFD-------- 1291
VVFNCSDGLDY A+GKFFKGL SCGAWA V Q + T
Sbjct: 1350 VVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD 1409
Query: 1292 ---FEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQL 1343
FEGT LKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMVPDYAMI ++
Sbjct: 1410 ILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEI 1464
Score = 578 bits (1428), Expect = e-163
Identities = 289/596 (48%), Positives = 391/596 (65%), Gaps = 18/596 (3%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
EQLSSQ+HYDYGMRAVK+VL+AAGNLK +PNE+E +LLLRSI DVNLPKFLS D+PLFE
Sbjct: 1490 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 1549
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
GI SDLFPG+ LPKPDY + L A D C + NLQ F K++Q YEMMIVRHGFM+VG
Sbjct: 1550 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 1609
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
PF GK+ +VL+ AL+ I E+ + + VLNPK+VTMGQLYG FD +S+EW+DG
Sbjct: 1610 EPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDG 1669
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
++A FR FAS TP RKW++FDGPVDAVWIENMNTVLDDNKKLCL SGE++ MS M++
Sbjct: 1670 VLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNL 1729
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
IFE MDL ASPATVSRCGMIYME LG+ P SW+N L +E+I + D +
Sbjct: 1730 IFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRM 1789
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIE----GEEDTKYTRTWFLASL 1696
V ++RK +L + NLV S + L++ MD+ + E + + T +
Sbjct: 1790 VPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIF 1849
Query: 1697 MTAIVWGLGGILNTDSREKFDDLVKEY------------FKGEKGI-PSKIERIDVSIPA 1743
+ +++W +G D R KF+ +++E FK + G + + + V P
Sbjct: 1850 LFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPE 1909
Query: 1744 EGMLIDHFYMYKGKGCWKTWPDAVK-AVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
+G + D+ ++ +G G W+ W +K A + + + + ++PTL+T ++ L+ L + +
Sbjct: 1910 KGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQ 1969
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
KP + +GPTGTGKS Y+ NFL+N L+ E Y P I +A QTQ++V+SKL KRRK
Sbjct: 1970 KPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKG 2029
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFIYD 1918
+GP GK ++F+DD+NMPA+EVYGAQP IELLR + D +WYDLK + + D
Sbjct: 2030 VFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVD 2085
>AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein.
Length = 4031
Score = 1940 bits (4811), Expect = 0.0
Identities = 920/1876 (49%), Positives = 1256/1876 (66%), Gaps = 8/1876 (0%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ T +Y +A +NL PTPAKSHY+FNLRDFSRVIQG L R E+ + + ++W+HE+
Sbjct: 2160 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEV 2219
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQ-DEKGEVNQENIKKMMFGC 2043
+RV+YDRL+D+ DR+W +++ R++M + F + D G V ++++ +MF C
Sbjct: 2220 LRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMF-C 2278
Query: 2044 YLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRIL 2103
E + Y EI + I L EYN++ K M +VLF +A+EH+S+I RIL
Sbjct: 2279 DFHDPKRE-DTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRIL 2337
Query: 2104 SMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGL 2163
P +ALLVGVGGSGRQS+TRLA+ + VFQ EI+K Y +WH+D+K++LR+
Sbjct: 2338 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 2397
Query: 2164 NKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLA--AQGGNRNL 2221
FLFT++QIKEES+++++ +LLN+GE+PNL+ LDEKQEI + +R + +
Sbjct: 2398 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 2457
Query: 2222 DISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALE 2281
D SP+ + F+ C+++LH+VL SPIG +FR RLR +P+LVNCCTIDW+ SWPEDAL+
Sbjct: 2458 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 2517
Query: 2282 MVAHHYMVKVNVPDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSF 2341
VA ++ ++ + + ++ + CK FH +S FF R Y+T SYL+LI +F
Sbjct: 2518 AVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTF 2577
Query: 2342 TTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEI 2401
L +K+ E+ K RY GL++L A+ VA MQ +L AL PQL V +++ +MM I
Sbjct: 2578 KLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMI 2637
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
E E+ K V+ D+ +K +C+ADLA ALPILE A+AAL+TL D
Sbjct: 2638 EKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQD 2697
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLD 2521
IT+VKSMK+PP VKLVM A+C+ + DFWGP+KR+LGDM FL
Sbjct: 2698 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQ 2757
Query: 2522 SLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXX 2581
SL +DKDNIP A M IRK Y+ N DF P + AS AAEGLCKW+IAMD YD
Sbjct: 2758 SLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIV 2817
Query: 2582 XXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCI 2641
M L +K+A + KK LE++V LC
Sbjct: 2818 APKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCS 2877
Query: 2642 DKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII 2701
KL RAE+LIGGLGGEK RW+ A L LY NL GDIL+S G++AYL +T R
Sbjct: 2878 KKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQT 2937
Query: 2702 DKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLL 2761
+W L ++P S+ LG + I+ W IAGLP D FSIDN II N+ RW L+
Sbjct: 2938 KEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLM 2997
Query: 2762 IDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPV 2821
IDPQ QANKWIK MEK N L V+K ++ +Y++ +E C+++G P L++ V E+++ L+P+
Sbjct: 2998 IDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPL 3057
Query: 2822 LLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGL 2881
LLK T+ QGG I LGD+ IEY P+FR Y+TTKLRNPHYLPE KVTL+NF +T +G+
Sbjct: 3058 LLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGM 3117
Query: 2882 EDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIE 2941
+DQ LGIVVA+ERPDL+E+++ LI+QGA N+ LK++ED IL L ++G+ILEDE+AI+
Sbjct: 3118 QDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIK 3177
Query: 2942 VLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYS 3001
+L SSK LA +I +KQE + ETE I+ R+GYRPIA HS++L++ + +L N++PMYQYS
Sbjct: 3178 ILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYS 3237
Query: 3002 LTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKM 3061
LTWFINL+I+SIEN+ KS+ L KRL+ LKD FTY+LY NVCRSLF+KDKL+FSF + +
Sbjct: 3238 LTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINL 3297
Query: 3062 MLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKT 3121
+L +N E++FL+TGGI ++N P WLP K+WDEICRL+DL AF+ R +F++
Sbjct: 3298 LLHERAINKAEWRFLLTGGIGLDNPYANPCTWLPQKSWDEICRLDDLPAFKTIRREFMRL 3357
Query: 3122 IIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYT 3181
W++VYD +EP ++ P W+++ +FQ++L++R LRPDK+ + +F+ +GR +
Sbjct: 3358 KDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFI 3417
Query: 3182 TPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF-SHRFNSISLGQGQGPI 3240
PPPFD++K+FGDSNC APLIF+LSPG+DPM AL+K+ + G+ + +S+SLGQGQGPI
Sbjct: 3418 EPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPI 3477
Query: 3241 ARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQ 3300
A M+EKA EG WV LQNCHLA SW+P LEK+ E +T FR+WLTSYPS FP
Sbjct: 3478 AMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPV 3537
Query: 3301 SVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVV 3360
SVLQ GVKMTNE P GL+ N+ RSY+ +P+ +PEF+ C K + F KLLYG+ FFHA+V
Sbjct: 3538 SVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCK-KPEEFKKLLYGLCFFHALV 3596
Query: 3361 QERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDD 3420
QER+KFGPLGWNI Y FN++D +ISV QL MFLNQYEE+ Y A++Y+TGECNYGGRVTDD
Sbjct: 3597 QERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDD 3656
Query: 3421 WDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVF 3480
WDRR + +IL+ + N +V + +Y F G Y +P +++ Y+++ +++P+ P PE+F
Sbjct: 3657 WDRRTLRSILNKFFNPELVENSDYKFDSSG-IYFVPPSGDHKSYIEYTKTLPLTPAPEIF 3715
Query: 3481 GLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEI 3540
G++ NA IT+D S + L +++L ++ +AS+IL KLP FD+E
Sbjct: 3716 GMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEA 3775
Query: 3541 AQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAML 3600
A ++YP Y +SMNTVL+QEM RFNKLL I+ S ++QKA+KGL VMS L+ +++L
Sbjct: 3776 AMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSIL 3835
Query: 3601 LGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGS 3660
KIPE W SYPSLKPL SYV DF+ RL L+ WY+ G PP FWL GFFFTQAFLTG+
Sbjct: 3836 NVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGA 3895
Query: 3661 VQNYARAKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPK 3720
QNYAR TIPIDLL FD+E+ PP+ GVF+ GLF+DG WNR+ +AE PK
Sbjct: 3896 QQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPK 3955
Query: 3721 VLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPS 3780
+L D +PV+WL P + + + Y PLYKT ER+GVL+TTGHS+NFV+A LPSD+P
Sbjct: 3956 ILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPK 4015
Query: 3781 AHWIKRSVALLLQLDN 3796
HWI R VALL QL++
Sbjct: 4016 EHWIGRGVALLCQLNS 4031
Score = 762 bits (1884), Expect = 0.0
Identities = 455/1315 (34%), Positives = 712/1315 (54%), Gaps = 101/1315 (7%)
Query: 101 PMLKSWERKIRNLIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTVIRDV--PGVPR 158
PM SW + +L+P +L+ F + L +E ++++ ++ V V++D G +
Sbjct: 186 PMEDSWLEHVLDLVPQHLKV-FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDK 244
Query: 159 KRYEEPHFK--FKGVTSNYGK-LLKYRRKLQDGSLLLHPFIRLILESSEKTFP-LHIIDL 214
K E P + + + + K L ++D ++P + +L+ F L ++D+
Sbjct: 245 KTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDI 304
Query: 215 AKYR-AKGPMSLDEFRLKVLDEIKRADYLVSSTWY----GILVQWLKNPRCLKGMKPRKV 269
++ + + L F+ ++ + A + W+ I Q K + G K+
Sbjct: 305 KEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKL 364
Query: 270 NDFVKCATKMISMQIQELMRQSINAIIDFL-KDPEAI-----PVLNVCLDFDGEFI-YDP 322
F CA ++++Q+Q+L S+ D + + P+++ P + L D + I ++P
Sbjct: 365 ESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEP 424
Query: 323 TLETIYEVFHNIADAISHISQRLMPIEQYLKIPYNYDALPVVYNEWLHKDGHERLQQQLN 382
L ++F N+ D + + +E L + + P + + + ++++
Sbjct: 425 ELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIK 484
Query: 383 -IVFKPLNQYVEKLR--QEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDSNI- 438
++ K E LR +Y+ L A+ ++ F+ E ++E++ ++I YQ + I
Sbjct: 485 EVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQ 544
Query: 439 -TAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAAK 497
T++ + C+ ++ L RA ++A + + H N +C EFE IA K
Sbjct: 545 YTSIKTICLGMFEMHCE-ELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEK 603
Query: 498 ALKEPENATELIEQGVYILHAKTVLVEALKERILVQINIISNLLEMTSLSSDHVKSNTRT 557
AL P N EL+E YI + + L++R++ N ++ L+E + S ++ N
Sbjct: 604 ALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSV 663
Query: 558 VNWLKDIKPIFEKNAAAYETFKADMEESLLGKIAYLNKEVTDMTPYLELLDNMDDVNHTL 617
W + IFE++ + +E L + +E+ E + D+
Sbjct: 664 FQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQ 723
Query: 618 EYLEYLRKLVHRLHDCDKLVTWINNEETTFKFPVTNYPELEELKEFIIPFYSLVYLVHRW 677
YL+ + L +L + N EE F + + YP+ +++++ + P+ L +
Sbjct: 724 RYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEF 783
Query: 678 KRSYYTWMDGPFEYLDHNQIEQDHDFYYKEFLKISKNYRNKIKQQIAEGVEKRFQGLVDD 737
+Y W +GP+ ++ +Q+E D Y++ K+ K + +
Sbjct: 784 SSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDS------------------- 824
Query: 738 PDVNNLPAPMKLCAQAVAEIKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDLTPTAGT 797
P + + + ++++D++ ++ + ++CNP L RHW+ MS I G+ L P+ +
Sbjct: 825 ------PYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS 878
Query: 798 SLRKIINFNLWGDLDQYEIISVAATKELALITNLNKMMAEW------------------- 838
++ ++ NL +D++E IS AA+KE +L + KM+ EW
Sbjct: 879 TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILA 938
Query: 839 ----IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLL 894
IQ +LDDHI+KT MRGS F+KP+E Q+R W K++ + +DEW KVQ+ WLYL
Sbjct: 939 SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 998
Query: 895 PIFSSKDIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLE 954
PIFSS DI++QMPEEG F V+ +R M SV +D HVL + +LE + + LE
Sbjct: 999 PIFSSPDIMSQMPEEGRRFTAVDKTWRDTMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1058
Query: 955 KINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGE 1014
I G+N YLEKKRL+FPRFFFLSNDE+LEILSETK+P +VQPHLKKCFEGI ++ F
Sbjct: 1059 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1118
Query: 1015 FNISAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGR 1074
+I+ M S EGE VE +++IS A ARG VEKWLV++E M+ ++ T + + Y R
Sbjct: 1119 LDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYER 1178
Query: 1075 VEWVLSWEGMVVLAISQIYWAVDVHESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLT 1134
+ WV W G VL +SQI+W +V ++ + L+ + +Q+++ V ++ R L+
Sbjct: 1179 INWVRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLV-RGKLS 1236
Query: 1135 KLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEERVYVKIINAVVH 1194
+ +T+ AL+V+DVHA+DV+S L+KK +++ +DF+WL+QLRYYW+E + K+INA +
Sbjct: 1237 MQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQENHLETKMINAGLR 1296
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y YEYLGNS RLVITPLTDRCYRTL GA +LHL GAPEGPAGTGKTETTKDLAKA+A QC
Sbjct: 1297 YGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 1356
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAWA---------------VRQHLETFD-------- 1291
VVFNCSDGLDY A+GKFFKGL SCGAWA V Q + T
Sbjct: 1357 VVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD 1416
Query: 1292 ---FEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQL 1343
FEGT LKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMVPDYAMI ++
Sbjct: 1417 ILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEI 1471
Score = 578 bits (1428), Expect = e-163
Identities = 289/596 (48%), Positives = 391/596 (65%), Gaps = 18/596 (3%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
EQLSSQ+HYDYGMRAVK+VL+AAGNLK +PNE+E +LLLRSI DVNLPKFLS D+PLFE
Sbjct: 1497 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 1556
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
GI SDLFPG+ LPKPDY + L A D C + NLQ F K++Q YEMMIVRHGFM+VG
Sbjct: 1557 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 1616
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
PF GK+ +VL+ AL+ I E+ + + VLNPK+VTMGQLYG FD +S+EW+DG
Sbjct: 1617 EPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDG 1676
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
++A FR FAS TP RKW++FDGPVDAVWIENMNTVLDDNKKLCL SGE++ MS M++
Sbjct: 1677 VLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNL 1736
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
IFE MDL ASPATVSRCGMIYME LG+ P SW+N L +E+I + D +
Sbjct: 1737 IFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRM 1796
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIE----GEEDTKYTRTWFLASL 1696
V ++RK +L + NLV S + L++ MD+ + E + + T +
Sbjct: 1797 VPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIF 1856
Query: 1697 MTAIVWGLGGILNTDSREKFDDLVKEY------------FKGEKGI-PSKIERIDVSIPA 1743
+ +++W +G D R KF+ +++E FK + G + + + V P
Sbjct: 1857 LFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPE 1916
Query: 1744 EGMLIDHFYMYKGKGCWKTWPDAVK-AVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
+G + D+ ++ +G G W+ W +K A + + + + ++PTL+T ++ L+ L + +
Sbjct: 1917 KGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQ 1976
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
KP + +GPTGTGKS Y+ NFL+N L+ E Y P I +A QTQ++V+SKL KRRK
Sbjct: 1977 KPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKG 2036
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFIYD 1918
+GP GK ++F+DD+NMPA+EVYGAQP IELLR + D +WYDLK + + D
Sbjct: 2037 VFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVD 2092
>AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dynein
type 3 protein.
Length = 4116
Score = 1839 bits (4560), Expect = 0.0
Identities = 878/1909 (45%), Positives = 1258/1909 (65%), Gaps = 19/1909 (0%)
Query: 1895 LLRLYFDQKHWYDLKTTDKLFIYDTIFYGA--IAATTDIYDQARENLRPTPAKSHYIFNL 1952
L +++ W+ K D +F+ YG + AT IY A EN PTP+KSHY+FNL
Sbjct: 2220 LTKIFSSIVDWHFGKGFDVMFLR----YGKMLVQATKTIYRDAVENFLPTPSKSHYVFNL 2275
Query: 1953 RDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYDRLVDDQDRAWFFGVLKKSTRDF 2012
RDFSRVIQG L + + I++WIHE+ RVFYDRL+D +DR FF ++K++T +
Sbjct: 2276 RDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNC 2335
Query: 2013 MKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSAEGERRYEEIPSKEVFLNIAVSM 2072
K T E L + G++ +NI+ + FG Y +S ++ Y+EI + +
Sbjct: 2336 FKQTIEKVL-IHLSPTGKIVDDNIRSLFFGDYFKPES--DQKIYDEITDLKQLTVVMEHY 2392
Query: 2073 LSEYNSMHKAKMTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGRQSLTRLASTILG 2132
L E+N++ KA M++V+F +A+EH+S+ICR+L G+ LLVG+GGSGRQS +L++ +
Sbjct: 2393 LEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNA 2452
Query: 2133 QQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSG 2192
+++Q EITK+Y+ DW +D+K ++ + G K T FLF ++QIK+ES++++++ LLN+G
Sbjct: 2453 YELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTG 2512
Query: 2193 EVPNLYGLDEKQEILELVRLAAQGGNRNLDISPLQILAFFVGRCKAKLHIVLCFSPIGSS 2252
+VPN++ DEK +I+E ++ AA+ ++++PL + FF+ R K+ L SPIG +
Sbjct: 2513 DVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDA 2572
Query: 2253 FRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSSAVIACKQFHVDA 2312
FR RLR++PSL+NCCTIDW+ SWP DALE+VA+ ++ V + D ++ V CK F
Sbjct: 2573 FRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVELDDNIRVEVVSMCKYFQESV 2632
Query: 2313 RIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADA 2372
+ +S+D++N R Y+T SYL+LI +F TL N K++E+ + RY GL +L AA
Sbjct: 2633 KKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQ 2692
Query: 2373 VAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXEL 2432
VA+MQR+L AL+PQLI+ +E++AKMM +IE ET AD V+ D+K +
Sbjct: 2693 VAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGI 2752
Query: 2433 KKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXX 2492
K +CE DLA A+P LE A+AAL+TL PADI++VKSM+NPP VKLVM ++C+
Sbjct: 2753 KNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPER 2812
Query: 2493 XXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPH 2552
+ D+WG SK+ILGD+ FL+SLK +DKDNIP TM++IR+ ++++ +F+P
Sbjct: 2813 KPDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPA 2872
Query: 2553 IVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXX 2612
++ S+A EGLCKW+ AM++YD M L +K+A +
Sbjct: 2873 VIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLV 2932
Query: 2613 XXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLY 2672
N KKK LE+ +++C KL RAEKLI GLGGEK RWT AA L Y
Sbjct: 2933 VDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRY 2992
Query: 2673 DNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQ 2732
NL GD+L+S G +AYL +T+ R++ ++W +P F LG IKI+
Sbjct: 2993 TNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIR 3052
Query: 2733 NWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYM 2792
W IAGLP D FSIDN II NS RW+L+IDP GQANKWIK MEK N L V+KF+D NYM
Sbjct: 3053 AWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYM 3112
Query: 2793 KVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYM 2852
+++E L+ G P LI+ + E+++A ++P+LLK T+ Q G E++ LG+N+IEY +F+LY+
Sbjct: 3113 RMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYI 3172
Query: 2853 TTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANR 2912
TT+LRNPHYLPE+ KV L+NF +T GL+DQ LGIV AKE+P+L+EK+ +LIV+ A N+
Sbjct: 3173 TTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNK 3232
Query: 2913 AALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRL 2972
LK++ED IL L +KG+ILEDE+AI+VL SSK L+ +I +KQ+ + TET I++ R+
Sbjct: 3233 KHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRM 3292
Query: 2973 GYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDT 3032
GY+P+A HSA +++C+++L N++PMYQYSLTWFINLY+ S+ ++ KS++L R+K++ D
Sbjct: 3293 GYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDH 3352
Query: 3033 FTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHLKKPV- 3091
FT ++Y+NVCRSLF+KDKL+FS ++ +M +++ + + FL+TGGIA++N P
Sbjct: 3353 FTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAP 3412
Query: 3092 EWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQ-F 3150
+WL +KAW EI R + L + + + +W+ +YD P + LPG W + +Q
Sbjct: 3413 QWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSW--KFSQGL 3470
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSD 3210
+K++++R LRPDK+ AV +F+ + MG+ Y P FD+ S+ DS+C APLIF+LSP +D
Sbjct: 3471 EKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSAD 3530
Query: 3211 PMGALIKYCERMGF-SHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPV 3269
PM L+K+ + +G R +ISLGQGQGPIA MI A +G WV LQNCHLA SW+P
Sbjct: 3531 PMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPT 3590
Query: 3270 LEKIVEGFDL-TNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISE 3328
LEKI E + +T+ FRLWLTSYPS+KFP S+LQ G+KMTNEPP GL+ NL RSY+++
Sbjct: 3591 LEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLND 3650
Query: 3329 PLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQ 3388
P+ +P F++ C K + K+L+G+ FFHAVVQER+ FGPLGWNI Y FN+SD +IS+ Q
Sbjct: 3651 PISDPVFFQSC-AKAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQ 3709
Query: 3389 LQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCE 3448
+QMFLN Y+E+ + A+ YLTGECNYGGRVTDD DRRL++++L + + D Y
Sbjct: 3710 IQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEED--YYSLA 3767
Query: 3449 LGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXX 3508
G Y +P YQ Y+ ++ ++PI PEVFGLH NA IT+D + +L ++L
Sbjct: 3768 PGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPR 3827
Query: 3509 XXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLL 3568
++ +A +ILSKLP FD+E K YPV Y ESMNTVL QE+ RFN+L
Sbjct: 3828 QSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLT 3887
Query: 3569 NEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIE 3628
++ SL +L +A+KG ++MS L+ N+ML+GK+P W SYPSLKPL YVAD +
Sbjct: 3888 KVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLA 3947
Query: 3629 RLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVD-YE 3687
RL+ ++W G P FW+ GF+FTQ+FLTG QNYAR TIPID + F+FE+ +
Sbjct: 3948 RLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVM 4007
Query: 3688 TTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKC 3747
P+ G +++GLF++G RW+R+T I E LPK+L D +P+IWL P F Y C
Sbjct: 4008 ENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVC 4067
Query: 3748 PLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQLDN 3796
P+YKT R+G L+TTGHS+N+VL+ LP+D P HWI R VA L QLDN
Sbjct: 4068 PVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLDN 4116
Score = 1178 bits (2917), Expect = 0.0
Identities = 672/1625 (41%), Positives = 942/1625 (57%), Gaps = 142/1625 (8%)
Query: 397 QEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDSNITAVLENEYFNCAVVC--Q 454
++Y L A++ + F+ E ++ KI + + I ++ N A+ C
Sbjct: 611 KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASM--NITVPLAMFCLDA 668
Query: 455 LRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAAKALKEPENATELIEQGVY 514
+ L RA + +I V + N SIC+++ IA K + P N EL+ +
Sbjct: 669 TALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEF 728
Query: 515 ILHAKTVLVEALKERILVQINIISNLLEMTSL--SSDHVKSNTRTVNWLKDIKPIFEKNA 572
+ + V V L+ ++ + L++ L + + N+R N L + +++
Sbjct: 729 LKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYQIEDIFDNSR--NLL-----LHKRDQ 781
Query: 573 AAYETFKADMEESLLGKIAYLNKEVTDMTPYLELLDNMDDVNHTLEYLEYLRKLVHRLHD 632
A + K E L ++ ++E+ E++ +++ H +E L L K ++R
Sbjct: 782 AEMDLIKRCSEFEL--RLEGYHRELESFRKR-EVMTT-EEMKHNVEKLNELSKNLNRAFA 837
Query: 633 CDKLVTWINNEETTFKFPVTNYPELEELKEFIIPFYSLVYLVHRWKRSYYTWMDGPFEYL 692
+L IN EE + + YP L+ + + +P+ L + + WM+GP L
Sbjct: 838 EFEL---INKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLL 894
Query: 693 DHNQIEQDHDFYYKEFLKISKNYRNKIKQQIAEGVEKRFQGLVDDPDVNNLPAPMKLCAQ 752
+ QI ++ ++ K+ K ++++PAP +L
Sbjct: 895 NAEQIAEEIGNMWRTTYKLIKT-------------------------LSDVPAPRRLAEN 929
Query: 753 AVAEIKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLD 812
+I ++ + + I CNP + RHW ++S I G+++ PT T L ++ F ++
Sbjct: 930 VKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVE 989
Query: 813 QYEIISVAATKELALITNLNKMMAEW-----------------------IQSVLDDHIVK 849
+ E I AA+KE +L NL++M +W IQ +LDDH++K
Sbjct: 990 KLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIK 1049
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
T M GS F+KP EA+ R W EK++R+ +D W K Q+ WLYL PIFSS+DI+AQMPEE
Sbjct: 1050 TQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIFSSEDIIAQMPEE 1109
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRL 969
G F V++ ++ M KD +L A + E + A LE I G+N+YLEKKRL
Sbjct: 1110 GRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRL 1169
Query: 970 YFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEFNISAMISMEGEQVE 1029
+FPRFFFLSNDE+LEILSETK+PL+VQPHLKKCFEGI +L F I MIS E E V
Sbjct: 1170 FFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEIVGMISSEKETVP 1229
Query: 1030 FLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGRVEWVLSWEGMVVLAI 1089
F+ I A A+G VEKWL QVE+ ML +++ + Y + R WVL W G VV+ +
Sbjct: 1230 FIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICV 1289
Query: 1090 SQIYWAVDVHESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDV 1149
S I+W +V ++L + L + F + Q+ + V ++R L+ + +T+ AL VIDV
Sbjct: 1290 SSIFWTQEVSQALAENTLLD---FLKKSNDQIAQIVQLVRGK-LSSGARLTLGALTVIDV 1345
Query: 1150 HAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEERVYVKIINAVVHYAYEYLGNSDRLVIT 1209
HA+DV++ L + +V+++ DFQW++QLRYYW + V V+II Y YEYLGNS RLVIT
Sbjct: 1346 HARDVVAKLSEDRVSDLNDFQWISQLRYYWVAKDVQVQIITTEALYGYEYLGNSPRLVIT 1405
Query: 1210 PLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMG 1269
PLTDRCYRTL+GA L+L GAPEGPAGTGKTETTKDLAKALA QCVVFNCSDGLDYKAMG
Sbjct: 1406 PLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMG 1465
Query: 1270 KFFKGLASCGAWA--------------------------VRQHLETFDFEGTTLKLNPAC 1303
KFFKGLA GAWA + + L+TF FEGT L LNP C
Sbjct: 1466 KFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTC 1525
Query: 1304 YVCITMNPGYAGRSELPDNLKVLF--------------------------RTVAM-MVPD 1336
V ITMNPGYAGR+ELPDNLK LF R++A +V
Sbjct: 1526 AVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVAT 1585
Query: 1337 YAMI-EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFD 1395
Y + EQLSSQ+HYDYGMRAVK+VL+AAGNLK +P E+ESVLLLR++ DVNL KFL+ D
Sbjct: 1586 YRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQD 1645
Query: 1396 VPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHG 1455
VPLF+GIISDLFPG+ LPKPDYE FL +D + LQP+ F+ K+IQ YEMM+VRHG
Sbjct: 1646 VPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHG 1705
Query: 1456 FMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISY 1515
+M+VG+P GK+ KVL+ AL +H NQ + YK++NPKA+TMGQLYG FD +S+
Sbjct: 1706 YMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSH 1765
Query: 1516 EWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMS 1575
EW DG++A FRE AS + RKWI+FDGPVDA+WIENMNTVLDDNKKLCL SGE++ M+
Sbjct: 1766 EWMDGVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMN 1825
Query: 1576 NVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYD 1635
+ MS+IFE DL QASPATVSRCGMIYME LG+ P S+++TL +E++E + D
Sbjct: 1826 SKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVND 1885
Query: 1636 MCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMD--NAIEGEE-------DTK 1686
M WL P + + R C +V ++L S +RL L+D A+E EE ++
Sbjct: 1886 MFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQ 1945
Query: 1687 YTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKG---EKGIPSKIERIDVSI-P 1742
W + ++VW + G +N DSR+KFD + G P ++ +I P
Sbjct: 1946 QIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFP 2005
Query: 1743 AEGMLIDHFYMYKGKGCWKTWPDAV--KAVQVKEQINLLQTVIPTLETEKFMYLLNLHSK 1800
G + D +++ + G W+TW + + +V + + +IPT+ET + + L +
Sbjct: 2006 ERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKTYLD 2065
Query: 1801 YLKPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRR 1860
+ P+L +GPTGTGKS NFL+ +L Y P I SANQTQD+++SKL +RR
Sbjct: 2066 HEIPMLFVGPTGTGKSAITNNFLL-HLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRR 2124
Query: 1861 KNNYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFIYDTI 1920
K +GP GK A++F+DD+NMPAKEVYGAQP IELLR + D +W+D K T +L I D +
Sbjct: 2125 KGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDML 2184
Query: 1921 FYGAI 1925
A+
Sbjct: 2185 LVTAM 2189
>AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein.
Length = 2536
Score = 1684 bits (4175), Expect = 0.0
Identities = 798/1663 (47%), Positives = 1106/1663 (66%), Gaps = 8/1663 (0%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ T +Y +A +NL PTPAKSHY+FNLRDFSRVIQG L R E+ + + ++W+HE+
Sbjct: 878 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEV 937
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQ-DEKGEVNQENIKKMMFGC 2043
+RV+YDRL+D+ DR+W +++ R++M + F + D G V ++++ +MF C
Sbjct: 938 LRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMF-C 996
Query: 2044 YLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRIL 2103
E + Y EI + I L EYN++ K M +VLF +A+EH+S+I RIL
Sbjct: 997 DFHDPKRE-DTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRIL 1055
Query: 2104 SMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGL 2163
P +ALLVGVGGSGRQS+TRLA+ + VFQ EI+K Y +WH+D+K++LR+
Sbjct: 1056 KQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEG 1115
Query: 2164 NKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLA--AQGGNRNL 2221
FLFT++QIKEES+++++ +LLN+GE+PNL+ LDEKQEI + +R + +
Sbjct: 1116 EMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQT 1175
Query: 2222 DISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALE 2281
D SP+ + F+ C+++LH+VL SPIG +FR RLR +P+LVNCCTIDW+ SWPEDAL+
Sbjct: 1176 DGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQ 1235
Query: 2282 MVAHHYMVKVNVPDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSF 2341
VA ++ ++ + + ++ + CK FH +S FF R Y+T SYL+LI +F
Sbjct: 1236 AVASRFLEEIEMSEEIRDGCIDMCKSFHTSTIDLSKSFFVELQRYNYVTPTSYLELISTF 1295
Query: 2342 TTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEI 2401
L +K+ E+ K RY GL++L A+ VA MQ +L AL PQL V +++ +MM I
Sbjct: 1296 KLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMI 1355
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
E E+ K V+ D+ +K +C+ADLA ALPILE A+AAL+TL D
Sbjct: 1356 EKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQD 1415
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLD 2521
IT+VKSMK+PP VKLVM A+C+ + DFWGP+KR+LGDM FL
Sbjct: 1416 ITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQ 1475
Query: 2522 SLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXX 2581
SL +DKDNIP A M IRK Y+ N DF P + AS AAEGLCKW+IAMD YD
Sbjct: 1476 SLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIV 1535
Query: 2582 XXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCI 2641
M L +K+A + KK LE++V LC
Sbjct: 1536 APKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCS 1595
Query: 2642 DKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII 2701
KL RAE+LIGGLGGEK RW+ A L LY NL GDIL+S G++AYL +T R
Sbjct: 1596 KKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQT 1655
Query: 2702 DKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLL 2761
+W L ++P S+ LG + I+ W IAGLP D FSIDN II N+ RW L+
Sbjct: 1656 KEWTTLCKGRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLM 1715
Query: 2762 IDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPV 2821
IDPQ QANKWIK MEK N L V+K ++ +Y++ +E C+++G P L++ V E+++ L+P+
Sbjct: 1716 IDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPL 1775
Query: 2822 LLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGL 2881
LLK T+ QGG I LGD+ IEY P+FR Y+TTKLRNPHYLPE KVTL+NF +T +G+
Sbjct: 1776 LLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGM 1835
Query: 2882 EDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIE 2941
+DQ LGIVVA+ERPDL+E+++ LI+QGA N+ LK++ED IL L ++G+ILEDE+AI+
Sbjct: 1836 QDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIK 1895
Query: 2942 VLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYS 3001
+L SSK LA +I +KQE + ETE I+ R+GYRPIA HS++L++ + +L N++PMYQYS
Sbjct: 1896 ILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYS 1955
Query: 3002 LTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKM 3061
LTWFINL+I+SIEN+ KS+ L KRL+ LKD FTY+LY NVCRSLF+KDKL+FSF + +
Sbjct: 1956 LTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINL 2015
Query: 3062 MLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKT 3121
+L +N E++FL+TGGI ++N WLP K+WDEICRL+DL AF+ R +F++
Sbjct: 2016 LLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRL 2075
Query: 3122 IIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYT 3181
W++VYD +EP ++ P W+++ +FQ++L++R LRPDK+ + +F+ +GR +
Sbjct: 2076 KDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFI 2135
Query: 3182 TPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF-SHRFNSISLGQGQGPI 3240
PPPFD++K+FGDSNC APLIF+LSPG+DPM AL+K+ + G+ + +S+SLGQGQGPI
Sbjct: 2136 EPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQGQGPI 2195
Query: 3241 ARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQ 3300
A M+EKA EG WV LQNCHLA SW+P LEK+ E +T FR+WLTSYPS FP
Sbjct: 2196 AMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPV 2255
Query: 3301 SVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVV 3360
SVLQ GVKMTNE P GL+ N+ RSY+ +P+ +PEF+ C K + F KLLYG+ FFHA+V
Sbjct: 2256 SVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCK-KPEEFKKLLYGLCFFHALV 2314
Query: 3361 QERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDD 3420
QER+KFGPLGWNI Y FN++D +ISV QL MFLNQYEE+ Y A++Y+TGECNYGGRVTDD
Sbjct: 2315 QERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGECNYGGRVTDD 2374
Query: 3421 WDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVF 3480
WDRR + +IL+ + N +V + +Y F G Y +P +++ Y+++ +++P+ P PE+F
Sbjct: 2375 WDRRTLRSILNKFFNPELVENSDYKFDSSG-IYFVPPSGDHKSYIEYTKTLPLTPAPEIF 2433
Query: 3481 GLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEI 3540
G++ NA IT+D S + L +++L ++ +AS+IL KLP FD+E
Sbjct: 2434 GMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDILGKLPNNFDIEA 2493
Query: 3541 AQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVK 3583
A ++YP Y +SMNTVL+QEM RFNKLL I+ S ++QKA+K
Sbjct: 2494 AMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIK 2536
Score = 578 bits (1428), Expect = e-163
Identities = 289/596 (48%), Positives = 391/596 (65%), Gaps = 18/596 (3%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
EQLSSQ+HYDYGMRAVK+VL+AAGNLK +PNE+E +LLLRSI DVNLPKFLS D+PLFE
Sbjct: 215 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFE 274
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
GI SDLFPG+ LPKPDY + L A D C + NLQ F K++Q YEMMIVRHGFM+VG
Sbjct: 275 GITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVG 334
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
PF GK+ +VL+ AL+ I E+ + + VLNPK+VTMGQLYG FD +S+EW+DG
Sbjct: 335 EPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDG 394
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
++A FR FAS TP RKW++FDGPVDAVWIENMNTVLDDNKKLCL SGE++ MS M++
Sbjct: 395 VLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNL 454
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
IFE MDL ASPATVSRCGMIYME LG+ P SW+N L +E+I + D +
Sbjct: 455 IFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRM 514
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIE----GEEDTKYTRTWFLASL 1696
V ++RK +L + NLV S + L++ MD+ + E + + T +
Sbjct: 515 VPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEGIF 574
Query: 1697 MTAIVWGLGGILNTDSREKFDDLVKEY------------FKGEKGI-PSKIERIDVSIPA 1743
+ +++W +G D R KF+ +++E FK + G + + + V P
Sbjct: 575 LFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPE 634
Query: 1744 EGMLIDHFYMYKGKGCWKTWPDAVK-AVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
+G + D+ ++ +G G W+ W +K A + + + + ++PTL+T ++ L+ L + +
Sbjct: 635 KGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQ 694
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
KP + +GPTGTGKS Y+ NFL+N L+ E Y P I +A QTQ++V+SKL KRRK
Sbjct: 695 KPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKG 754
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFIYD 1918
+GP GK ++F+DD+NMPA+EVYGAQP IELLR + D +WYDLK + + D
Sbjct: 755 VFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVD 810
Score = 248 bits (607), Expect = 3e-64
Identities = 128/189 (67%), Positives = 138/189 (73%), Gaps = 26/189 (13%)
Query: 1181 EERVYVKIINAVVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKT 1240
E + K+INA + Y YEYLGNS RLVITPLTDRCYRTL GA +LHL GAPEGPAGTGKT
Sbjct: 1 ENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKT 60
Query: 1241 ETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWA---------------VRQ 1285
ETTKDLAKA+A QCVVFNCSDGLDY A+GKFFKGL SCGAWA V Q
Sbjct: 61 ETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQ 120
Query: 1286 HLETFD-----------FEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMV 1334
+ T FEGT LKL+P C V ITMNPGYAGRSELPDNLK LFRTVAMMV
Sbjct: 121 QILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMV 180
Query: 1335 PDYAMIEQL 1343
PDYAMI ++
Sbjct: 181 PDYAMIAEI 189
>AK128592-1|BAC87517.1| 1093|Homo sapiens protein ( Homo sapiens cDNA
FLJ46751 fis, clone TRACH3022960, weakly similar to
Dynein beta chain, ciliary. ).
Length = 1093
Score = 1322 bits (3275), Expect = 0.0
Identities = 595/1090 (54%), Positives = 813/1090 (74%), Gaps = 4/1090 (0%)
Query: 2710 KLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQAN 2769
K +P SE+F+ LG +KI+ W IAGLP D FSIDN +I +N RW L+IDPQGQAN
Sbjct: 5 KKKIPCSEEFLLSKTLGDPVKIRAWNIAGLPTDTFSIDNGVIVNNCRRWPLMIDPQGQAN 64
Query: 2770 KWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQ 2829
KWIK E+ N L V+K +D +YM+ +E C+++G P L++ V E+++ L+P+LL+ T+ Q
Sbjct: 65 KWIKNSERENQLSVIKLSDSDYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLRQTFKQ 124
Query: 2830 GGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIV 2889
GG + I LG+ +IEY +F+ Y+TTKLRNPHY+PE+ KV+L+NF +T +GLEDQ LGIV
Sbjct: 125 GGIDCIRLGEVIIEYSFDFKFYITTKLRNPHYMPELATKVSLLNFMITPEGLEDQLLGIV 184
Query: 2890 VAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNL 2949
VAKERP+L+E+R LI+Q AAN+ LK +E IL TL ++G+ILEDESAI+VLDS+K +
Sbjct: 185 VAKERPELEEERNALILQSAANKKQLKDIEKKILETLSSSEGNILEDESAIKVLDSAKMM 244
Query: 2950 AIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLY 3009
+ +I KKQ+ + +TE I + R GYRPIA HS+VL++ + +L N+DPMYQYSLTWF+NLY
Sbjct: 245 SNEITKKQQIAEKTELKIAESREGYRPIAKHSSVLFFSIADLANIDPMYQYSLTWFVNLY 304
Query: 3010 IISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMN 3069
I SI ++NKSK LEKRL++L D FTYNLY N+CRSLF+KDKL+FSF++C+ ++L+ +++
Sbjct: 305 INSIHDSNKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIE 364
Query: 3070 VDEYKFLITGGIAVENHLKKP-VEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEV 3128
E FL+TGG+++++ K P WL DK+W+EICR ++ AFR R F + I +W+E+
Sbjct: 365 YQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREI 424
Query: 3129 YDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDI 3188
YD EP N P D+ L + QK++++R LRPDK+T A++ ++ ++G+K+ PPPFD+
Sbjct: 425 YDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDL 484
Query: 3189 SKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFS-HRFNSISLGQGQGPIARAMIEK 3247
+KS+ DSNC PLIF+LSPG+DPM +L+K+ S ++F +ISLGQGQGPIA MI+
Sbjct: 485 TKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKA 544
Query: 3248 AQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGV 3307
A EG WVCLQNCHLAVSW+P+LEKI E F + SFRLWLTSYPS KFP ++LQ GV
Sbjct: 545 AIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGV 604
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
KMTNEPPTGL+ NL +SY+++P+ +PEF++GC GK+ + KLL+G+ FFHA+VQERKKFG
Sbjct: 605 KMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFG 664
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
PLGWNI YGFN+SD +IS+ QLQ+F+N+Y+ I + AI YLTGECNYGGRVTDDWDRRL++
Sbjct: 665 PLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLL 724
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
T+L ++ N +V +P+Y F G Y P + Y+DY++ I+ +P PE+FGLH N
Sbjct: 725 TMLADFYNLYIVENPHYKFSPSG-NYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVD 783
Query: 3488 ITRDYSISMELTSSLVLV-XXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYP 3546
I++D + L SL+L IL+ + +IL+KLP FD+E+A +KYP
Sbjct: 784 ISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYP 843
Query: 3547 VDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPE 3606
V Y ESMNTVL+QEMERFN L+ I+++L+DL+KA+KG++VM AL+ S ++L+GK+PE
Sbjct: 844 VRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPE 903
Query: 3607 NWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYAR 3666
W K SYPSLKPL SY+ DF+ RL+ L+DWY +GKP FWL GFFFTQAFLTG++QNYAR
Sbjct: 904 IWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYAR 963
Query: 3667 AKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNM 3726
T PIDLL ++FE+ D T P+ GV++ GL++DG RW+RE+ +AEQ PK+L D M
Sbjct: 964 KYTTPIDLLGYEFEVIPSDTSDTSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLM 1023
Query: 3727 PVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKR 3786
P+IW+ P K+ + Y CPLYKT ERKG L+TTGHS+NFV+A L +D+P+ HWIKR
Sbjct: 1024 PIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKR 1083
Query: 3787 SVALLLQLDN 3796
VALL QLD+
Sbjct: 1084 GVALLCQLDD 1093
>AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein.
Length = 2182
Score = 1260 bits (3121), Expect = 0.0
Identities = 683/1930 (35%), Positives = 1093/1930 (56%), Gaps = 103/1930 (5%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ A+ +IY++ +L PTPAKSHY+FNLRD S+ +QG + + +++ HE
Sbjct: 294 VEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHEC 353
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
RVF+DRL++++D+ +F +L + + LE + + K ++FG +
Sbjct: 354 QRVFHDRLINNEDKHYFHVILTEMANKHFGIAID--LEYFLN----------KPIIFGDF 401
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
+ + + +R Y+++P E N+ L +YN + ++ +V F A+EH+S+I R++
Sbjct: 402 IKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIR 461
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
GNALLVGVGG+G+QSLTRLA+ I G + Q E+++ Y+ +H+D++ + + +G +
Sbjct: 462 QERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVED 521
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQG-----GNR 2219
K+ FLFT++QI E ++++++++LNSGEVPNL+ DE +++L R A+ GNR
Sbjct: 522 KNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNR 581
Query: 2220 NLDISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDA 2279
+ ++ +F+ + + KLHIVLC SP+G +FR+R R++PSLVNCCTIDW+ WP +A
Sbjct: 582 D------EVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREA 635
Query: 2280 LEMVAHHYMVKVNVP-DPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLI 2338
L V+ + +V+ + +K + C H+ ++ ++N R Y T SYL+LI
Sbjct: 636 LLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELI 695
Query: 2339 KSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMM 2398
+ ++ + K++++ +A+ R NGL +L + V M+ DL+AL+P L+ +E +M
Sbjct: 696 NLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALM 755
Query: 2399 QEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLK 2458
+++ V+ AD+ V+ED+ + D + DL ALP L+ A AL++L
Sbjct: 756 EKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLD 815
Query: 2459 PADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMG 2518
ADI+ ++ PP V VM A+ + W +K++LGD
Sbjct: 816 KADISEIRVFTKPPDLVMTVMEAISILLNAKPD---------------WPSAKQLLGDSN 860
Query: 2519 FLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXX 2578
FL L +DK+NI + K++K Y++N DF P V K S A + +C W+ AMD+Y
Sbjct: 861 FLKRLLEYDKENIKPQILAKLQK-YINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVV 919
Query: 2579 XXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQ 2638
TMA L EK+A++ +K++L +
Sbjct: 920 KVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMA 979
Query: 2639 LCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRI 2698
L +L RA KL L E+VRW + + + N+ G++ ++ +AY +T R
Sbjct: 980 LTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQ 1039
Query: 2699 EIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRW 2758
+I+ W L +P F ++LG +I+ W GLPRDL S +N I+ RW
Sbjct: 1040 SLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRW 1099
Query: 2759 SLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPL 2818
L+IDPQ QAN+WI+ E + L+++K TD N+++++E + G P L++ + E ++ L
Sbjct: 1100 PLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPAL 1159
Query: 2819 DPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTK 2878
+P+LLK ++ GG+ I LGD+ I+Y NFR YMTTK+ NPHYLPE+ KVT+INF +TK
Sbjct: 1160 EPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTK 1219
Query: 2879 DGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDES 2938
GLEDQ L VV E+P L+E+R KLIV+ ++ LK +E+ ILR L ++G+IL++E
Sbjct: 1220 SGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEE 1279
Query: 2939 AIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMY 2998
I+ L SK + I + E + TE +I R YRP+A+ +V+Y+ + L +DPMY
Sbjct: 1280 LIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMY 1339
Query: 2999 QYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMC 3058
QYSL +F L+ +IE + K+++L++RL L + Y NV R LF++ KL++SF++C
Sbjct: 1340 QYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLC 1399
Query: 3059 SKMMLSTEKMNVDEYKFLITG--GIAVENHLKKPVEWLPDKAWDEICRLND-LKAFRAFR 3115
+MM ++ E+ F + G G+ E K WLP W C L + F
Sbjct: 1400 VEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLT 1459
Query: 3116 DDFV-----------KTII---KWQEVYDDIEPQNKTL--------PGGWDERLTQFQKL 3153
+ + +T I KW E Y ++ ++K + W L+ F KL
Sbjct: 1460 QNILSHPISIRLGSFETYINPQKW-EGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKL 1518
Query: 3154 LVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMG 3213
++++ + +K+ A++ F+ + +G+++ PP D+ + D +C PL+FILS GSDPMG
Sbjct: 1519 ILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMG 1578
Query: 3214 ALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKI 3273
A ++ G+S R SISLGQGQGPIA M++ A G WV LQNCHLAVSW+ +E++
Sbjct: 1579 AFQRFARESGYSERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEEL 1638
Query: 3274 VEGFDLTNTDL--SFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLK 3331
++ F ++ + +FRL+L+S PS+ FP +VLQ VK+TNEPP GL+ N+ R++
Sbjct: 1639 IKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRANIRRAFTE---M 1695
Query: 3332 EPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQM 3391
P F+E K + ++++GI FFHA++QERKKFGPLGWNI Y FNDSD + +++ L++
Sbjct: 1696 TPSFFEE-NILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKL 1754
Query: 3392 FLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQ 3451
+ + +I + A+ Y+TGE YGGRVTD WD+R + TIL + + + + +Y + E G
Sbjct: 1755 YCKE-GKIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEE-DYKYSESG- 1811
Query: 3452 QYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVX-XXXX 3510
Y P Q++ +IE++P+ PE+FG+H NA + Y + L ++++ V
Sbjct: 1812 IYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSST 1871
Query: 3511 XXXXXXXXXILVLMASEILSKLPPKFDVEIAQKK-YPVDYN---ESMNTVLIQEMERFNK 3566
I+ + + + +++P K ++E A + + D S+ TVL QE++RFN
Sbjct: 1872 GGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNN 1931
Query: 3567 LLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADF 3626
LL I +SL+ L KA+ G +VMS ++ N+ L ++P W +YPSLKPL S+V D
Sbjct: 1932 LLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDL 1991
Query: 3627 IERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEI----R 3682
I R S ++ W + G+P ++W+ GFFF Q FLTG++QN+AR +PID L F + + R
Sbjct: 1992 ILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYR 2051
Query: 3683 N------------------VDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLND 3724
+ +D E P+ GV V G+FMD RW+ + I + LP +N
Sbjct: 2052 DQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNP 2111
Query: 3725 NMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWI 3784
+PV+ P+ +N T Y CPLYKT R G L+TTGHS+NFV+ LPS + +WI
Sbjct: 2112 VLPVVHFEPQ-QNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWI 2170
Query: 3785 KRSVALLLQL 3794
+ ALL QL
Sbjct: 2171 AKGSALLCQL 2180
Score = 103 bits (246), Expect = 2e-20
Identities = 64/225 (28%), Positives = 102/225 (45%), Gaps = 11/225 (4%)
Query: 1683 EDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIP 1742
E TK T + + +W LGG L + + FD ++ F + D +P
Sbjct: 5 EQTKLN-TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD---------DNPDARLP 54
Query: 1743 AEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
G L + K W + + + + ++PT +T ++ YL+
Sbjct: 55 NSGDLWSIHMDFDTKRL-DPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVK 113
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
+L G TG GKS + L + Y P ++ S+ +TQ+++ SKL ++RKN
Sbjct: 114 HSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKN 173
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
G K +IF+DD+NMP + YG+QP IELLR Y D +YD
Sbjct: 174 ILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYD 218
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 1249 bits (3094), Expect = 0.0
Identities = 676/1883 (35%), Positives = 1030/1883 (54%), Gaps = 59/1883 (3%)
Query: 1927 ATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMR 1986
AT D+Y+ + PTP K HY+FNLRD S+V QG K+ D K + ++WIHE R
Sbjct: 2628 ATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFR 2687
Query: 1987 VFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLD 2046
VF DRLVD D F G++ F TF + + +FG +L
Sbjct: 2688 VFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPP------------IFGDFLK 2735
Query: 2047 TDSAEGERRYEEIPSKEVFLNIAVSMLSEYN-SMHKAKMTIVLFDYALEHLSKICRILSM 2105
YE++ V + + L+EYN S M +VLF A+EH+++I R++
Sbjct: 2736 EPKV-----YEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQ 2790
Query: 2106 PSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNK 2165
P GN LLVG+GGSGRQSL RLAS+I FQ E+TK Y +++ DDIK + R++G K
Sbjct: 2791 PRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELK 2850
Query: 2166 DTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDISP 2225
T+F+F ++QI +ES++++++++L+SGEVPNLY DE +EI + Q + S
Sbjct: 2851 TTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQS--HIIDQARVEQVPESS 2908
Query: 2226 LQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAH 2285
+ A+ + R + LHIVLC SP+G FR +R YP+LVNC TI+W+ WP++AL VA
Sbjct: 2909 DSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAE 2968
Query: 2286 HYMVKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTT 2343
++ V++ + + H S R Y+T YL+L+ +
Sbjct: 2969 KCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKK 3028
Query: 2344 LTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEV 2403
L K++EL A + GL ++ + + V +M +L K ++ ++ + + I
Sbjct: 3029 LLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQ 3088
Query: 2404 ETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADIT 2463
+ AD+ V + + L + + DL ALP LE+A+ AL +L DI
Sbjct: 3089 QKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIG 3148
Query: 2464 IVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSL 2523
+KS PP V++VM AV + W +KR LG+ F+ SL
Sbjct: 3149 EIKSYGRPPAQVEIVMQAVMILRGNEPT---------------WAEAKRQLGEQNFIKSL 3193
Query: 2524 KNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXX 2583
NFDKDNI ++KI Y + DF+P I+ + S AA+ LC W+ AM++Y
Sbjct: 3194 INFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEP 3252
Query: 2584 XXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDK 2643
+ A L E + + +K+ L + + K
Sbjct: 3253 KRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELK 3312
Query: 2644 LFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK 2703
L RA L+ GL GEK RW + L+ L GD L++ ++Y+ P+ R EI+++
Sbjct: 3313 LERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQ 3372
Query: 2704 -WRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLI 2762
W + +L +P S F + L K+++W I GLP D FS +N II RW+L+I
Sbjct: 3373 IWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMI 3432
Query: 2763 DPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVL 2822
DPQ QA KWIK ME L+++ +Y++++E + +G P L+ V E ++ L+P+L
Sbjct: 3433 DPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPML 3492
Query: 2823 LKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLE 2882
K GG+ + +GD +EY+ NFR Y+TTKL NPHY PE K T++NFA+ + GLE
Sbjct: 3493 NKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLE 3552
Query: 2883 DQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEV 2942
Q LGIVV KERP+L+E+++ L++ AA + LK++ED+ILR L E G +L+D +
Sbjct: 3553 AQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNT 3612
Query: 2943 LDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSL 3002
L +SK A ++ ++ E S TE + R YRP A +++L++ + ++ +DPMYQ+SL
Sbjct: 3613 LHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSL 3672
Query: 3003 TWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMM 3062
+I+L+I+SI+ +++S LE R+ +L D TY +Y CR+LF++ KL+FSF MC+K++
Sbjct: 3673 DAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKIL 3732
Query: 3063 LSTEKMNVDEYKFLITGGIAV--ENHLKKPV-EWLPDKAWDEICRLNDLKAFRAFRDDFV 3119
++ K+N+DEY F + GG+ + E + P WL D WD I L+ L F + F
Sbjct: 3733 ETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFE 3792
Query: 3120 KTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRK 3179
+ W Y + P+ LPG W+ + Q++L+VR LR D++ V+ F+ +G +
Sbjct: 3793 QYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSR 3852
Query: 3180 YTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGP 3239
+ PP ++ DS +PL+FILSPG DP AL++ E MG + RF+++SLGQGQ P
Sbjct: 3853 FIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAP 3912
Query: 3240 IARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFP 3299
IA ++ + ++G WV L NCHL++SW+P L+K+VE + + SFRLWL+S P FP
Sbjct: 3913 IAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFP 3972
Query: 3300 QSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
S+LQV +KMT EPP GL+ N+ R Y + + EP+F C K + KLL+ + FFH+V
Sbjct: 3973 ISILQVSIKMTTEPPKGLKANMTRLY--QLMSEPQF-SRC-SKPAKYKKLLFSLCFFHSV 4028
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTD 3419
+ ERKKF LGWNI YGFNDSDF++S L ++L++YEE + A+KYL NYGG VTD
Sbjct: 4029 LLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTD 4088
Query: 3420 DWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEV 3479
DWDRRL+ T +++Y ++ P + L + Y +P+ Y ++I +P PPE
Sbjct: 4089 DWDRRLLTTYINDYFCDQSLSTPFHRLSAL-ETYFIPKDGSLASYKEYISLLPGMDPPEA 4147
Query: 3480 FGLHMNAGITRDYSISMELTSSLVLV--XXXXXXXXXXXXXXILVLMASEILSKLPPKFD 3537
FG H NA + + + L +L+ + ++ +A+++ K+P D
Sbjct: 4148 FGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMID 4207
Query: 3538 VEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSN 3597
E QK +D +N VL+QE++R+N L+ I SL DL+K ++GLIVMS +L+ N
Sbjct: 4208 YEGTQKLLALD-PSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFN 4266
Query: 3598 AMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPT-FWLPGFFFTQAF 3656
+L +P W K +YPS KPL ++ D R+ E W +PP FWL GF F F
Sbjct: 4267 CILDAHVPPLWGK-AYPSQKPLAAWTQDLAMRVEQFELWASRARPPVIFWLSGFTFPTGF 4325
Query: 3657 LTGSVQNYARAKTIPIDLLVFDFEIRNVDYETT--PPKWGVFVQGLFMDGGRWNRETHAI 3714
LT +Q+ AR + +D L ++F + VD PPK GV+V+GL+++G W+R+ +
Sbjct: 4326 LTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCL 4385
Query: 3715 AEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYL 3774
E P L MP I P + + Y CP Y R G + ++FV+ L
Sbjct: 4386 VEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAG----SSDRASFVIGIDL 4441
Query: 3775 PSDKPSA-HWIKRSVALLLQLDN 3796
S + HWIKR ALL+ LD+
Sbjct: 4442 RSGAMTPDHWIKRGTALLMSLDS 4464
Score = 402 bits (989), Expect = e-110
Identities = 244/655 (37%), Positives = 351/655 (53%), Gaps = 72/655 (10%)
Query: 755 AEIKDWRPNVQMAHIMCNPALVQRHWDEM--STIAGFDLTPTAGTSLRKIINFNLWGDLD 812
++I+ ++ + + + NPAL +RHWD++ FD + T L +I+ + ++
Sbjct: 1328 SKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFT-LEQIVELGMDQHVE 1386
Query: 813 QYEIISVAATKELALITNLNKMMAEW-----------------------IQSVLDDHIVK 849
+ IS +ATKELA+ L + W + L+D+ V
Sbjct: 1387 KIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVA 1446
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
M+ S FVK FE V W + + I+ VQ QW+YL IF +DI Q+P E
Sbjct: 1447 LSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNE 1506
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRL 969
+F +VN+ ++ M ++KD + L G+L+ LE I ++ YLE KR
Sbjct: 1507 STLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRH 1566
Query: 970 YFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFD------GEFNISAMISM 1023
FPRF+FLSND++LEIL +++NP VQPHLKKCF+ I L ++ M S
Sbjct: 1567 IFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSG 1626
Query: 1024 EGEQVEFLDMISVAAARGSVEKWLVQVEEQM---LKAVKSETEISYYDYPNMGRVEWVLS 1080
+GE ++FL + + G VE WL VE+ M L+ + ++ + N R +WV
Sbjct: 1627 DGEYIDFLHSVFL---EGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNK-RDKWVKE 1682
Query: 1081 WEGMVVLAISQIYWAVDVHESLNTHKLSE----LQAFHSELTKQLNETVAVIRRTDLTKL 1136
W G VV+ SQI W DV + L T K L+ LN+ IR +LTK+
Sbjct: 1683 WAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRG-NLTKI 1741
Query: 1137 SSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEER--VYVKIINAVVH 1194
+ + AL+ I++HA+DV+ L K + +V F WL+QLR+YWE++ ++ N
Sbjct: 1742 MRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQ 1801
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y YEYLGNS RLVITPLTDRCY TL A +LH G+P+GPAGTGKTET KDL KAL +
Sbjct: 1802 YNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYV 1861
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLE 1288
+V NCS+GLDYK+MG+ + GLA GAW A+ L
Sbjct: 1862 IVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLT 1921
Query: 1289 TFDFEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQL 1343
F F+G + L +C + ITMNPGYAGR+ELP+NLK +FR +AM+VPD +I ++
Sbjct: 1922 HFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEI 1976
Score = 363 bits (893), Expect = 7e-99
Identities = 201/590 (34%), Positives = 334/590 (56%), Gaps = 28/590 (4%)
Query: 1322 NLKVLFRTVAMMVPDYAM-IEQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLL 1380
N K+L + V + Y++ ++QLS Q+HYD+G+RA+ ++L AG +R P+ ++ +LL
Sbjct: 1985 NCKILAKKVYTL---YSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLL 2041
Query: 1381 RSITDVNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFL 1440
S+ D+N+ K S D PLF I+ DLFP I LP DY + LQ L
Sbjct: 2042 LSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTL 2101
Query: 1441 IKVIQTYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKA 1500
KV Q YE RH M+VG SGK+ + ++L +LS + P+ LNPKA
Sbjct: 2102 TKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKA 2161
Query: 1501 VTMGQLYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDD 1560
+++G+LYG +D + EWTDGI++++ R +++ P KWI+FDGPVD +WIENMN+V+DD
Sbjct: 2162 LSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDD 2221
Query: 1561 NKKLCLTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNT 1620
NK L L +GE +AM +S++FEV DL+ ASPATVSRCGM+Y + LG+ P+ +SWL
Sbjct: 2222 NKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEK 2281
Query: 1621 LNPIWLEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLM--DNA 1678
P + E + M + L + ++ + + C +LV E + + S +L L +N
Sbjct: 2282 -RP---KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENG 2337
Query: 1679 IEGEEDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERID 1738
+ + Y T + + +++W + ++ + R++ D ++E I+
Sbjct: 2338 VNPADGENYV-TMVEMTFVFSMIWSVCASVDEEGRKRIDSYLRE--------------IE 2382
Query: 1739 VSIPAEGMLIDHFYMYKGKGCWKTWPDAV-KAVQVKEQINLLQTVIPTLETEKFMYLLNL 1797
S P + + ++F K + W ++ D + K+ + + ++PT++T ++ YL++
Sbjct: 2383 GSFPNKDTVYEYFVDPKIRS-WTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSS 2441
Query: 1798 HSKYLKPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLV 1857
P+LL+GP GTGK+ Q+ ++ +L +++ + ++N Q ++ S++
Sbjct: 2442 LVANQNPILLVGPVGTGKTSIAQS-VLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVE 2500
Query: 1858 KRRKNNYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
KR K Y P GK I F+DD+NMPAK+++G+QP +EL+RL+ D WYD
Sbjct: 2501 KRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYD 2550
>AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein.
Length = 4355
Score = 1097 bits (2717), Expect = 0.0
Identities = 527/1150 (45%), Positives = 747/1150 (64%), Gaps = 9/1150 (0%)
Query: 2649 KLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLV 2708
+LI GL EKVRW ENLQ + +N++GD+LV+ G +AYL P+T R + D W +
Sbjct: 3211 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 3270
Query: 2709 IKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQA 2768
N+PH+ + LG +KI++W IAGLP D S++N +I S RW+ IDPQ QA
Sbjct: 3271 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 3330
Query: 2769 NKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYL 2828
NKWIK MEK N L V K +D ++++ +E + +GKP L++ V E+++ L+PVLLK TY
Sbjct: 3331 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 3390
Query: 2829 QGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGI 2888
Q G + LGD VI YH +FR+Y+TTKL NPHY PEI K+TLINF L+ GLEDQ LG
Sbjct: 3391 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 3450
Query: 2889 VVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKN 2948
VVA+ERPDL+E + +LI+ A R LK +ED IL L ++G+ ++D I+VL++SK
Sbjct: 3451 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 3510
Query: 2949 LAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINL 3008
A +I K + +TE I+ R+ Y P+A + +L++CV++L NVDPMYQYSL WF+N+
Sbjct: 3511 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 3570
Query: 3009 YIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKM 3068
++ I N+ ++ +L+KR+ + TY+LYSNVCRSLF+K KLMF+F++C ++M++ K+
Sbjct: 3571 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 3630
Query: 3069 NVDEYKFLITGG-IAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQE 3127
N E+++L++GG I++ P +WL D+AW +I L++L F +F DFVK + +++
Sbjct: 3631 NQSEWRYLLSGGSISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRV 3689
Query: 3128 VYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFD 3187
++D +EP + LPG WD+ L QFQKLLV+R LR DK+T A+ F+ + ++ P +
Sbjct: 3690 IFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTAN 3749
Query: 3188 ISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEK 3247
+S F DSN PLIF+LSPG+DP L K+ E M FS + ++ISLGQGQGP A AM+
Sbjct: 3750 LSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRS 3809
Query: 3248 AQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGV 3307
+ G WV QNCHLA SW+P LE+++E + FRLWLTS PS+KFP S+LQ G
Sbjct: 3810 SIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGS 3869
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
KMT EPP G++ NL +SY S L E +F C K F LL + FH ER+KFG
Sbjct: 3870 KMTIEPPRGVRANLLKSYSS--LGE-DFLNSC-HKVMEFKSLLLSLCLFHGNALERRKFG 3925
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
PLG+NI Y F D D +I + QL+MFL++Y++I Y +KY GE NYGGRVTDDWDRR I+
Sbjct: 3926 PLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIM 3985
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
IL+++ N V++ P + + G + +P + YL +I+S+P+N PE+FGLH NA
Sbjct: 3986 NILEDFYNPDVLS-PEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 4044
Query: 3488 ITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPV 3547
IT + + L +++ + I+ + IL K+P +++ KYPV
Sbjct: 4045 ITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPV 4104
Query: 3548 DYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPEN 3607
Y ESMNTVL+QE+ R+N+LL I +LQDL KA+KGL+VMS L+L + ++ +PE
Sbjct: 4105 LYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPEL 4164
Query: 3608 WRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARA 3667
W +YPSLKPL S+V D ++RL L+ W Q+G P FW+ GFFF QAFLTG++QN+AR
Sbjct: 4165 WSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARK 4224
Query: 3668 KTIPIDLLVFDFEIR-NVDYETTP-PKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDN 3725
I ID + FDF++ E T P+ G ++ GLF++G RW+ E +AE PK L
Sbjct: 4225 FVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTE 4284
Query: 3726 MPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIK 3785
M VIWL P + + Y CP+YKTL R G L+TTGHS+N+V+A +P+ +P HWIK
Sbjct: 4285 MAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIK 4344
Query: 3786 RSVALLLQLD 3795
R VAL+ LD
Sbjct: 4345 RGVALICALD 4354
Score = 581 bits (1435), Expect = e-164
Identities = 378/1105 (34%), Positives = 568/1105 (51%), Gaps = 113/1105 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHNIADAISHISQRLMPIEQYLKIPYNYDALPVVYN 366
++++ LD G Y LE N+ D + + +E+ + P++ +
Sbjct: 685 IMDLVLDSSGVH-YSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLES 743
Query: 367 EWLHKDGHERLQQQL-NIVFK---PLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
LH+ E L+ + + V K PL Y ++ R+ Y L L+ + + +
Sbjct: 744 VGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRK-YLELNNNDIASFLKTYQTQGLLAQ 802
Query: 423 ELRNKIKYY----QDIDSNITA--VLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGI 476
E+R + + + +DS++ + ++ Y N V Q L + ++ +
Sbjct: 803 EVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQ-----SLSKKRKALATSVLDIL 857
Query: 477 VKGHMAENESICSEFEIIAAKALKEPENATELIEQGVYILHAKTVLVEALKERILVQINI 536
K E +SIC EF I+ K ++P + EL E ++ LV L+ERI+ ++
Sbjct: 858 AKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLV-GLEERIVKVMDD 916
Query: 537 ISNLLE-MTSLSSDHVKSNTRTVNW----LKDIKPIFEKNAAAYETFKADM---EESLLG 588
+ E + +LSSD NW L I+ + +++ E F+ + +
Sbjct: 917 YQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQE 976
Query: 589 KIAYLNKEVTDMTPYLELLDNMDDVNHTLEYLEYLRKLVHRLHDCDKLVTWINNEETTFK 648
K+ L V + ++E ++ E +R++ +L DC +L NN E F
Sbjct: 977 KLEGLQLVVAGFSIHVE-------ISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFS 1029
Query: 649 FPVTNYPELEELKEFIIPFYSLVYLVHRWKRSYYTWMDGPFEYLDHNQIEQDHDFYYKEF 708
P+TNY +L + + P+ L W R +WM+ P +D Q+E++ +K
Sbjct: 1030 LPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTM 1089
Query: 709 LKISKNYRNKIKQQIAEGVEKRFQGLVDDPDVNNLPAPMKLCAQAVAEIKDWRPNVQMAH 768
K K +++ +PA ++ A I++++P + +
Sbjct: 1090 HKCVKQFKD-------------------------MPACQEVALDIRARIEEFKPYIPLIQ 1124
Query: 769 IMCNPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLDQYEIISVAATKELALI 828
+ NP + RHW+ +S ++ P A + + + NL ++ ++ A KE A+
Sbjct: 1125 GLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIE 1184
Query: 829 TNLNKMMAEW-----------------------IQSVLDDHIVKTVGMRGSAFVKPFEAQ 865
L+KM EW +LDDHIV T M S + KPFE +
Sbjct: 1185 QALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQR 1244
Query: 866 VRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEEGVMFVEVNNIYRRYMG 925
+ +W K+ ++EW Q WLYL PIFSS+DI Q+P E + + I+++ M
Sbjct: 1245 INSWENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMK 1304
Query: 926 SVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEI 985
+ ++ V+ + +L++ R L+ + G++ YLE KR FPRF+FLS+DE+LEI
Sbjct: 1305 NAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEI 1364
Query: 986 LSETKNPLKVQPHLKKCFEGINRLVFDGEFNISAMISMEGEQVEFLDMISVAAARGSVEK 1045
LS+TK+P VQPHL+KCFE I RL+F + I+ M S EGE+V+ I ++ +VE
Sbjct: 1365 LSQTKDPTAVQPHLRKCFENIARLLFQEDLEITHMYSAEGEEVQLCFSIYPSS---NVED 1421
Query: 1046 WLVQVEEQMLKAVKSETEISYYDYPNMGRVEWVLSWEGMVVLAISQIYWAVDVHESLNTH 1105
WL +VE M +V E + YP M R +WVL+W G V +A Q YW ++V E+L
Sbjct: 1422 WLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEALEAG 1481
Query: 1106 KLSELQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAKDVISDLIKKKVTE 1165
L Q F +L +QL++ VA++R L+++ + ALIVI+VHAKDV+S LI++ V
Sbjct: 1482 NLRS-QLF-PQLCQQLSDLVALVRGK-LSRMQRAVLSALIVIEVHAKDVVSKLIQENVVS 1538
Query: 1166 VTDFQWLAQLRYYWEEERVYVKIINAVVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYL 1225
V DFQW++QLRYYW +Y++ +NA Y YEYLGNS RLVITPLTDRCY TL GA +L
Sbjct: 1539 VNDFQWISQLRYYWTNNDLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHL 1598
Query: 1226 HLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAV-- 1283
GAP GPAGTGKTETTKDL KALA+Q VVFNCSD LD+ AMGKFFKGLAS GAWA
Sbjct: 1599 KFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFD 1658
Query: 1284 ------------------------RQHLETFDFEGTTLKLNPACYVCITMNPGYAGRSEL 1319
+Q +E F FEG + L P+C V ITMNPGYAGR+EL
Sbjct: 1659 EFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTEL 1718
Query: 1320 PDNLKVLFRTVAMMVPDYAMIEQLS 1344
PDNLK LFR VAMMVPDYAMI ++S
Sbjct: 1719 PDNLKALFRPVAMMVPDYAMITEIS 1743
Score = 471 bits (1160), Expect = e-131
Identities = 255/591 (43%), Positives = 352/591 (59%), Gaps = 29/591 (4%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
EQLSSQ+HYD+GMRAVKTV+SAAGNLKR P+ +E ++ LR+I DVN+PKFL D+ LF
Sbjct: 1768 EQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFS 1827
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
GI+SDLFP I DY A + C N+NL+ +E FL K IQ YE +VRHG MLVG
Sbjct: 1828 GIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVG 1887
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGC---ECTYKVLNPKAVTMGQLYGAFDPISYEW 1517
SGKS +VL+ A++ + + G Y VLNPK++TMGQLYG FD +++EW
Sbjct: 1888 PTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEW 1947
Query: 1518 TDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNV 1577
TDGI ++ R A +KW +FDGPVDA+WIENMNTVLDDNKKLCL+SGE++ ++
Sbjct: 1948 TDGIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEA 2007
Query: 1578 MSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMC 1637
M+M+FEV DL+ ASPATVSRCGM+Y+E + LG MPF + WL L P+ L+ EE+ +
Sbjct: 2008 MTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLPPL-LKPYEEHFKALF 2066
Query: 1638 DWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVE-----MLMDNAIEGEEDTKYTR--- 1689
+ + +VR +++ + NL +S L+L++ L ++ K +R
Sbjct: 2067 VSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVE 2126
Query: 1690 ---TWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKG--------EKGIPSKIERID 1738
WF+ SL +W +G ++ R F ++ + E+G+ D
Sbjct: 2127 LIEPWFIFSL----IWSVGATGDSSGRTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLED 2182
Query: 1739 VSIPAEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLH 1798
I D YK + W W D+ + N ++PT++T + +LL++
Sbjct: 2183 AGISGTNDSEDEEEEYK-QVAWVKWMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDML 2241
Query: 1799 SKYLKPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVK 1858
KP+L IGPTGTGK+ + + L+ NL ++ Y F+ SANQTQD + SKL K
Sbjct: 2242 LTNKKPVLCIGPTGTGKTLTISDKLLKNLALD-YISHFLTFSARTSANQTQDFIDSKLDK 2300
Query: 1859 RRKNNYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLK 1909
RRK +GP G++ I FIDD+NMPA E YGAQP IELLR + D WYD K
Sbjct: 2301 RRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWYDRK 2351
Score = 456 bits (1123), Expect = e-127
Identities = 253/730 (34%), Positives = 399/730 (54%), Gaps = 24/730 (3%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ AT +Y L PTPAKSHY FNLRD S+V QG + +++ +++W HE
Sbjct: 2438 VEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHEN 2497
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
RVF DRLV+++DR+WF +LK+ + + TF + +++G +
Sbjct: 2498 CRVFRDRLVNEEDRSWFDQLLKRCMEQW-EVTFNKVCP-------------FQPILYGDF 2543
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
+ S + YE I S+ + + + +YN ++ AK+ +VLF A+ H+ +I R L
Sbjct: 2544 MSPGS--DVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR 2601
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
GNALL+GVGGSGR SLTRLAS + + FQ E++K+Y + +W DD+K VL ++G N
Sbjct: 2602 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN 2661
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
TFLF+++QIK ES++++++++LNSG++PNLY DE+ +I+ +R Q + L +
Sbjct: 2662 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQ--EQGLQPT 2719
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
++A + GR ++ +H+VLC SPIG FR RLR +PSLVNCCTIDW++ WP +AL+ VA
Sbjct: 2720 KANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVA 2779
Query: 2285 HHYMVKVNVPDPVK---SSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSF 2341
++ ++ + + + C H I++ R Y+T SYL+L+ F
Sbjct: 2780 TVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIF 2839
Query: 2342 TTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEI 2401
+ L +K+ EL+ AK R +GLD+L + ++ VA MQ DL ++ P L A+ + M++I
Sbjct: 2840 SILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQI 2899
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
+V+TAIA++ V+ ++ + D + DL ALP L+ A+A+L L D
Sbjct: 2900 KVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKND 2959
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMG-FL 2520
+T V++M+ PP VKLV+ AVC+ + D+W P K +L D G FL
Sbjct: 2960 VTEVRAMQRPPPGVKLVIEAVCI-MKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFL 3018
Query: 2521 DSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXX 2580
+SL FDKDNI ++ I + Y+ N++F+P +AK S A +C+W+ AM Y
Sbjct: 3019 ESLFKFDKDNIGDVVIKAI-QPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKA 3077
Query: 2581 XXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLC 2640
T IL+E K + KK+ LE + + C
Sbjct: 3078 VEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQC 3137
Query: 2641 IDKLFRAEKL 2650
+L RA K+
Sbjct: 3138 EQRLGRAGKV 3147
>BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein.
Length = 1581
Score = 1048 bits (2595), Expect = 0.0
Identities = 572/1603 (35%), Positives = 896/1603 (55%), Gaps = 80/1603 (4%)
Query: 2247 SPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVP-DPVKSSAVIAC 2305
SP+G +FR+R R++PSLVNCCTIDW+ WP +AL V+ + +V+ + +K + C
Sbjct: 2 SPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMC 61
Query: 2306 KQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQ 2365
H+ ++ ++N R Y T SYL+LI + ++ + K++++ +A+ R NGL +
Sbjct: 62 VNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTK 121
Query: 2366 LGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXX 2425
L + V M+ DL+AL+P L+ +E +M+++ V+ AD+ V+ED+
Sbjct: 122 LLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVK 181
Query: 2426 XXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVX 2485
+ D + DL ALP L+ A AL++L ADI+ ++ PP V VM A+ +
Sbjct: 182 AEETQAIADDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISIL 241
Query: 2486 XXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLS 2545
W +K++LGD FL L +DK+NI + K++K Y++
Sbjct: 242 LNAKPD---------------WPSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQK-YIN 285
Query: 2546 NKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEK 2605
N DF P V K S A + +C W+ AMD+Y TMA L EK
Sbjct: 286 NPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREK 345
Query: 2606 KAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAA 2665
+A++ +K++L + L +L RA KL L E+VRW +
Sbjct: 346 QALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESI 405
Query: 2666 ENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVL 2725
+ + N+ G++ ++ +AY +T R +I+ W L +P F ++L
Sbjct: 406 QKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINIL 465
Query: 2726 GTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLK 2785
G +I+ W GLPRDL S +N I+ RW L+IDPQ QAN+WI+ E + L+++K
Sbjct: 466 GDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIK 525
Query: 2786 FTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYH 2845
TD N+++++E + G P L++ + E ++ L+P+LLK ++ GG+ I LGD+ I+Y
Sbjct: 526 LTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYD 585
Query: 2846 PNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLI 2905
NFR YMTTK+ NPHYLPE+ KVT+INF +TK GLEDQ L VV E+P L+E+R KLI
Sbjct: 586 KNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLI 645
Query: 2906 VQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETET 2965
V+ ++ LK +E+ ILR L ++G+IL++E I+ L SK + I + E + TE
Sbjct: 646 VRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQ 705
Query: 2966 IIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKR 3025
+I R YRP+A+ +V+Y+ + L +DPMYQYSL +F L+ +IE + K+++L++R
Sbjct: 706 MINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQR 765
Query: 3026 LKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITG--GIAV 3083
L L + Y NV R LF++ KL++SF++C +MM ++ E+ F + G G+
Sbjct: 766 LDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEK 825
Query: 3084 ENHLKKPVEWLPDKAWDEICRLND-LKAFRAFRDDFV-----------KTII---KWQEV 3128
E K WLP W C L + F + + +T I KW E
Sbjct: 826 ERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKW-EG 884
Query: 3129 YDDIEPQNKTL--------PGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKY 3180
Y ++ ++K + W L+ F KL++++ + +K+ A++ F+ + +G+++
Sbjct: 885 YSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQF 944
Query: 3181 TTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPI 3240
PP D+ + D +C PL+FILS GSDPMGA ++ G+S R SISLGQGQGPI
Sbjct: 945 IETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPI 1004
Query: 3241 ARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDL--SFRLWLTSYPSDKF 3298
A M++ A G WV LQNCHLAVSW+ +E++++ F ++ + +FRL+L+S PS+ F
Sbjct: 1005 AEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTF 1064
Query: 3299 PQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHA 3358
P +VLQ VK+TNEPP GL+ N+ R++ P F+E K + ++++GI FFHA
Sbjct: 1065 PVTVLQNSVKVTNEPPKGLRANIRRAFTE---MTPSFFEE-NILGKKWRQIIFGICFFHA 1120
Query: 3359 VVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVT 3418
++QERKKFGPLGWNI Y FNDSD + +++ L+++ + +I + A+ Y+TGE YGGRVT
Sbjct: 1121 IIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKE-GKIPWDALIYITGEITYGGRVT 1179
Query: 3419 DDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPE 3478
D WD+R + TIL + + + + +Y + E G Y P Q++ +IE++P+ PE
Sbjct: 1180 DSWDQRCLRTILKRFFSPETLEE-DYKYSESG-IYFAPMADSLQEFKDYIENLPLIDDPE 1237
Query: 3479 VFGLHMNAGITRDYSISMELTSSLVLVX-XXXXXXXXXXXXXILVLMASEILSKLPPKFD 3537
+FG+H NA + Y + L ++++ V I+ + + + +++P K +
Sbjct: 1238 IFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLE 1297
Query: 3538 VEIAQKK-YPVDYN---ESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALD 3593
+E A + + D S+ TVL QE++RFN LL I +SL+ L KA+ G +VMS ++
Sbjct: 1298 MEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEME 1357
Query: 3594 LQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFT 3653
N+ L ++P W +YPSLKPL S+V D I R S ++ W + G+P ++W+ GFFF
Sbjct: 1358 KVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFP 1417
Query: 3654 QAFLTGSVQNYARAKTIPIDLLVFDFEI----RN------------------VDYETTPP 3691
Q FLTG++QN+AR +PID L F + + R+ +D E P
Sbjct: 1418 QGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSP 1477
Query: 3692 KWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYK 3751
+ GV V G+FMD RW+ + I + LP +N +PV+ P+ +N T Y CPLYK
Sbjct: 1478 EDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQ-QNYKPSPTLYHCPLYK 1536
Query: 3752 TLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
T R G L+TTGHS+NFV+ LPS + +WI + ALL QL
Sbjct: 1537 TGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQL 1579
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy chain
DNAH5 protein.
Length = 4624
Score = 1041 bits (2577), Expect = 0.0
Identities = 610/1896 (32%), Positives = 982/1896 (51%), Gaps = 71/1896 (3%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ T ++ + + PTPAK HY+FNLRD SRV QG E +K+W HE
Sbjct: 2767 VPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHEC 2826
Query: 1985 MRVFYDRLVDDQDRAWF-----------FGVLKKSTRDFMKDT-FESALETYQDEKGEVN 2032
RV DR D WF FG KK D DT F L + GE +
Sbjct: 2827 KRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETS 2886
Query: 2033 QENIKKMMFGCYLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYN-SMHKAKMTIVLFDY 2091
+E AE + YE I S L YN S+ A M +V F
Sbjct: 2887 EE-------------ADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFAD 2933
Query: 2092 ALEHLSKICRILSMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHD 2151
A+ HL KI R++ P GNALLVGVGGSG+QSLTRLAS I G FQ +T+SY+ + +
Sbjct: 2934 AMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLME 2993
Query: 2152 DIKLVLRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEI-LELV 2210
D+K++ R +G K TF+FT+++IK+ES+++ ++++L+SGEV NL+ DE EI +L
Sbjct: 2994 DLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLA 3053
Query: 2211 RLAAQGGNRNLDISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTID 2270
+ + R L + + +F+ R + LHIVLCFSP+G FR R +P+L++ CTID
Sbjct: 3054 SVMKKEFPRCLPTNE-NLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTID 3112
Query: 2271 WYDSWPEDALEMVAHHYMVKVNVPD--PVKSSAVIACKQFHVDARIVSIDFFNHFGRETY 2328
W+ WP+DAL V+ H++ ++ +K V F +D+F F R T+
Sbjct: 3113 WFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTH 3172
Query: 2329 ITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLI 2388
+T SYL I+ + + K E+R R GL++L +A+++VA + ++L A + +L
Sbjct: 3173 VTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQ 3232
Query: 2389 VMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILE 2448
V +K+ +++E+ ++ A+K A+V++ + + K E L A P LE
Sbjct: 3233 VANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALE 3292
Query: 2449 DAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWG 2508
+A AAL T++P+DI V+++ PP+ + +M V + M W
Sbjct: 3293 EAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTM-PSWQ 3351
Query: 2509 PSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWI 2568
S +++ FL +L+ F KD I ++ + Y D+ + GLC W
Sbjct: 3352 ESLKLMTAGNFLQNLQQFPKDTINEEVIEFL-SPYFEMPDYNIETAKRVCGNVAGLCSWT 3410
Query: 2569 IAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNI 2628
AM + M L++ +A +
Sbjct: 3411 KAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMT 3470
Query: 2629 KKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAY 2688
+K+ L ++ + C K+ A LI GL GEK RWT ++ L GD+L++ ++Y
Sbjct: 3471 EKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSY 3530
Query: 2689 LAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDN 2748
P+ R +++ WR + +P + ++L I W + GLP D SI N
Sbjct: 3531 SGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQN 3590
Query: 2749 AIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALID 2808
II + R+ LLIDPQ Q WIK E N+LQ+ + +E L G+P LI+
Sbjct: 3591 GIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIE 3650
Query: 2809 CVLEDVEAPLDPVLLKLTYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFN 2867
V E+++ LD V L+ +++ G F + +GD ++ FRLY+TTKL NP Y PEI
Sbjct: 3651 DVGEELDPALDNV-LERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISA 3709
Query: 2868 KVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQ 2927
+ ++I+F +T GLEDQ LG V+ E+ +L+++R L+ AN+ +K++ED++L L
Sbjct: 3710 RTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLT 3769
Query: 2928 ETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYC 2987
T+G ++EDES I VL ++K A ++ +K E S ETE I R YRP+A+ ++LY+
Sbjct: 3770 STQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFL 3829
Query: 2988 VTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFD 3047
+TE+ V+ MYQ SL F+ L+ +S+ + KS KR+ + + TY +Y R L++
Sbjct: 3830 ITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYE 3889
Query: 3048 KDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRL 3105
+ K +F+ ++ K+ + ++ +E+ LI GG +++ KP +W+ D W + L
Sbjct: 3890 EHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVEL 3949
Query: 3106 NDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLT 3165
+ L+ F D + W+ +D P+ + LP +D+ L F++LL++R PD+
Sbjct: 3950 SKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTI 4009
Query: 3166 IAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFS 3225
+++ MG KY D+ K++ +S+ PLI +LS GSDP ++I +R+
Sbjct: 4010 AQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIE 4069
Query: 3226 HRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLS 3285
R+ +S+GQGQ AR ++++ + GGW LQNCHL + ++ L I+ +L + +
Sbjct: 4070 TRY--VSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHD--A 4125
Query: 3286 FRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKD 3343
FRLW+T+ +FP ++LQ+ +K N+PP GL+ L R+Y +S+ L +
Sbjct: 4126 FRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLD-------VSSG 4178
Query: 3344 KTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQ 3400
+ +LY ++F H+ VQER+KFG LGWNI Y FN +DF +V +Q L+ + +
Sbjct: 4179 SQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVS 4238
Query: 3401 YVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCE 3460
+ I+Y+ GE YGGRVTDD+D+RL+ T + + + P++ F Q Y +P+
Sbjct: 4239 WTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFG-PDFSFY---QGYNIPKCST 4294
Query: 3461 YQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLV-LVXXXXXXXXXXXXXX 3519
+YL++I+S+P PEVFGLH NA IT ++ ++ +++ +
Sbjct: 4295 VDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREA 4354
Query: 3520 ILVLMASEILSKLPPKF-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDL 3578
++ +A ++L KLPP + E+ ++ + + MN L QE++R ++L+ ++S+L +L
Sbjct: 4355 VVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTEL 4414
Query: 3579 QKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQ 3638
+ A+ G I+MS L + M +IP W+K S+ S L + + IER S W
Sbjct: 4415 KLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWIS-STLGFWFTELIERNSQFTSWVF 4473
Query: 3639 NGKPPTFWLPGFFFTQAFLTGSVQNYARA-KTIPIDLLVFDFEIRN--VDYETTPPKWGV 3695
NG+P FW+ GFF Q FLT Q RA K +D +V E+ D + PP GV
Sbjct: 4474 NGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGV 4533
Query: 3696 FVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLER 3755
+V GL+++G W++ + E PKVL + MPVI +Y + N + Y CP+YK R
Sbjct: 4534 YVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAE-NNTLRDPRFYSCPIYKKPVR 4592
Query: 3756 KGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALL 3791
+ N++ A L + + HW+ R VALL
Sbjct: 4593 TDL--------NYIAAVDLRTAQTPEHWVLRGVALL 4620
Score = 530 bits (1307), Expect = e-149
Identities = 380/1261 (30%), Positives = 599/1261 (47%), Gaps = 119/1261 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDL-TPTAGTSLRKIINFNLWGDLDQYE 815
I D+ + M + A+++RHW+ ++T+ G L LR I+ L ++ E
Sbjct: 1473 IDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIE 1532
Query: 816 IISVAATKELALITNLNKMMAEWIQSVLDDHIVKTVG---MRGSA--------------- 857
I ++A KE + L +++ EW KT G +RG +
Sbjct: 1533 DICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLL 1592
Query: 858 -------FVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEEG 910
+ PF+AQ++ W + + I+ W VQ+ W+YL +F DI Q+P+E
Sbjct: 1593 GSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEA 1652
Query: 911 VMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKRL 969
F ++ + + M + P V++ G L + LE + YLEKKRL
Sbjct: 1653 KRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRL 1712
Query: 970 YFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEFNISAMISMEGEQVE 1029
FPRFFF+S+ +LEIL + + +Q HL F+ I + F + ++S+ ++ E
Sbjct: 1713 CFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKI-YDRILSISSQEGE 1771
Query: 1030 FLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGMVVL 1087
+++ A G+VE WL + E+ ++ + + G E++ S+ V L
Sbjct: 1772 TIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGL 1831
Query: 1088 AISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALI 1145
Q+ W D E+L K + +Q + + LN + V R DL+ + + LI
Sbjct: 1832 LGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTR-DLSSTERVKYETLI 1890
Query: 1146 VIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYLGNS 1203
I VH +D+ DL + DF+WL Q R+Y+ E+ ++ + I + Y E+LG +
Sbjct: 1891 TIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCT 1950
Query: 1204 DRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGL 1263
DRLVITPLTDRCY TL A + + GAP GPAGTGKTETTKD+ + L VVFNCSD +
Sbjct: 1951 DRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 2010
Query: 1264 DYKAMGKFFKGLASCGAWAV--------------------------RQHLETFDF-EGTT 1296
D++ +G+ FKGLA G+W ++H ++F F +G
Sbjct: 2011 DFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDN 2070
Query: 1297 LKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMI--EQLSSQNHYDYGMR 1354
+ +NP + +TMNPGYAGR ELP+NLK+ FR+VAMMVPD +I +L+S D +
Sbjct: 2071 VTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVL 2130
Query: 1355 A-----------------------VKTVLSAAGNL---KRSFPNESESVLLLRSITDVNL 1388
A ++ +LS L KR+ P ++ES +++R + D+NL
Sbjct: 2131 ARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL 2190
Query: 1389 PKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYE 1448
K + D PLF +I DLFP I L K Y A E L + +KVIQ +E
Sbjct: 2191 SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFE 2250
Query: 1449 MMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYG 1508
VRHG M +G +GK+ + L A++ + +P +NPKA+T Q++G
Sbjct: 2251 TQRVRHGMMTLGPSGAGKTTCIHTLMRAMT---DCGKPH----REMRMNPKAITAPQMFG 2303
Query: 1509 AFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTS 1568
D + +WTDGI +T++R+ WI+ DGPVDA+WIEN+N+VLDDNK L L +
Sbjct: 2304 RLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLAN 2363
Query: 1569 GEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEE 1628
G+ + M+ +IFE ++ ASPATVSR GM++M S+ L + P + +L +P +
Sbjct: 2364 GDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSP----Q 2419
Query: 1629 NEEYIYDMCDWLFDPLVYYVRKFCGQ-LVTAGEVNLVISTLRLVEMLMDNAIEGEEDTKY 1687
E + + F P +Y +FC Q L EV + + ML E+ +
Sbjct: 2420 EAEILRQLYTESF-PDLY---RFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEV 2475
Query: 1688 TRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGML 1747
++ + A++W G L D R + + ++ G +P D +
Sbjct: 2476 SQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFD----- 2530
Query: 1748 IDHFYMYKGKGCWKTWPDAVKAVQVKEQI--NLLQTVIPTLETEKFMYLLNLHSKYLKPL 1805
Y G W W + ++P ++ + +L+ +K K +
Sbjct: 2531 ----YYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAV 2586
Query: 1806 LLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYG 1865
LLIG GT K+ ++ F M+ D E + + + Q + S + KR YG
Sbjct: 2587 LLIGEQGTAKTVIIKGF-MSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYG 2645
Query: 1866 PTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIFYGA 1924
P GK +FIDD+NMP +G Q E++R +Q +Y+L K + I D F A
Sbjct: 2646 PPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAA 2705
Query: 1925 I 1925
+
Sbjct: 2706 M 2706
>AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein.
Length = 3051
Score = 1032 bits (2554), Expect = 0.0
Identities = 614/1890 (32%), Positives = 990/1890 (52%), Gaps = 72/1890 (3%)
Query: 1928 TTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRV 1987
T +Y ++L PTP+K HYIFNLRD SRV G L E +++W +E +RV
Sbjct: 1212 TLALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRV 1271
Query: 1988 FYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDT 2047
F+DRL+ + D+ ++++ + + F+ +E + ++FG +
Sbjct: 1272 FHDRLISETDKQ----LVQQHIGSLVVEHFKDDVEVVMRDP----------ILFGDF-QM 1316
Query: 2048 DSAEGERR-YEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILSMP 2106
EGE R YE+I E + +L EYN + KM +VLFD ALEHL+++ RI+ M
Sbjct: 1317 ALHEGEPRIYEDIQDYEAAKALFQEILEEYNESN-TKMNLVLFDDALEHLTRVHRIIRMD 1375
Query: 2107 SGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKD 2166
G+ALLVGVGGSG+QSL+RLA+ +VF+ +++ YS + +D+K + + G NK
Sbjct: 1376 RGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKA 1435
Query: 2167 TTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDISPL 2226
FLFT++ + EE +++ ++++L SG VP L+ +EK+ IL ++ + + + +
Sbjct: 1436 MIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILS--QIGQEALKQGMGPAKE 1493
Query: 2227 QILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHH 2286
+ +FV + LHIVL SP+G + RT R +P +VN IDW+ WP AL VA
Sbjct: 1494 SVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKS 1553
Query: 2287 YM-VKVNVPDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLT 2345
++ +P + V H S F R Y+T +YLD I +++ L
Sbjct: 1554 FLGYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLL 1613
Query: 2346 NRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNA-LKPQLIVMAEKSAK---MMQEI 2401
+ K + A R GLD+L +A I +LN L Q IV+AEKSA +++EI
Sbjct: 1614 DEKTQCNIAQCKRLDGGLDKLKEAT----IQLDELNQKLAEQKIVLAEKSAACEALLEEI 1669
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
V TA+A++ E K + E LA +PILE A L L +D
Sbjct: 1670 AVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSD 1729
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLD 2521
+T ++S PP V+ V + + W +K ++ D FL
Sbjct: 1730 VTEIRSFAKPPKQVQTVCECILIMKGYKELN--------------WKTAKGVMSDPNFLR 1775
Query: 2522 SLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXX 2581
SL D D+I + ++ I K L + + S A G+ K++ A+ Y
Sbjct: 1776 SLMEIDFDSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREI 1834
Query: 2582 XXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCI 2641
T LE + + ++K+ L++E ++
Sbjct: 1835 KPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIME 1894
Query: 2642 DKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII 2701
+L A+KLI GLG E +RW + L L GD L+ ++Y +T R E++
Sbjct: 1895 RRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMV 1954
Query: 2702 DK-WRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSL 2760
++ W++ +++ +P S+ F + +L D++I W GLP D S+ N I+ + R+ L
Sbjct: 1955 NRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPL 2014
Query: 2761 LIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDP 2820
IDPQ QA WIK E+ N+L+V F D +++K +E ++YG P L V E ++ +D
Sbjct: 2015 CIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDN 2074
Query: 2821 VLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDG 2880
VL K + G++FI LGD ++Y NFRLY+ TKL NP Y P +F K +IN+ +T G
Sbjct: 2075 VLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKG 2134
Query: 2881 LEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAI 2940
LEDQ L ++VA ER +L+E+RE LI + + N+ LK +ED +LR L + G++L++ +
Sbjct: 2135 LEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLV 2194
Query: 2941 EVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQY 3000
L+ +K+ A ++ +K + + +T I++ R GYRP A A+L++ ++E+ V+ MYQY
Sbjct: 2195 HTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQY 2254
Query: 3001 SLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSK 3060
SL F+ ++ +S++ + L KRL+ + DT T+++Y++ C LF++ KL+FSF M K
Sbjct: 2255 SLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIK 2314
Query: 3061 MMLSTEKMNVDEYKFLITGGIAVE-NHLKKPVEWLPDKAWDEICRLNDLKA--FRAFRDD 3117
+ + ++ +E F + G I++E + KKP WL D+ W++I L+++ + F DD
Sbjct: 2315 IEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDD 2374
Query: 3118 FVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMG 3177
WQE YD + +P G+D +T FQKLL++R R D++ AV+ ++ MG
Sbjct: 2375 VENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMG 2434
Query: 3178 RKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF-SHRFNSISLGQG 3236
KY PP F S +P++FILSPGSDP L+K ER GF +R +++GQG
Sbjct: 2435 EKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQG 2494
Query: 3237 QGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSD 3296
Q +A ++E A + G W+ LQNCHL V WL LEK +E +T FRLWLT+ P+
Sbjct: 2495 QEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLE--RITKPHPDFRLWLTTDPTK 2552
Query: 3297 KFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFF 3356
FP +LQ +K+ EPP GL+ N+ +Y E + CP F L+Y ++FF
Sbjct: 2553 GFPIGILQKSLKVVTEPPNGLKLNMRATYFK---ISHEMLDQCP--HPAFKPLVYVLAFF 2607
Query: 3357 HAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQ-YEE----IQYVAIKYLTGEC 3411
HAVVQER+KFG +GWN+ Y FN+SDFQ+ + L +L + +++ I + ++KYL GE
Sbjct: 2608 HAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEV 2667
Query: 3412 NYGGRVTDDWDRRLIVTILDNYVNSGVVN--DPNYLFCELGQQYGLPRRCEYQDYLKHIE 3469
YGGR D +DRR++ +D Y+ + + P + F Y +P E + +++ IE
Sbjct: 2668 MYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIE 2727
Query: 3470 SVPINPPPEVFGLHMNAGITRDYSISMELTSSLV-LVXXXXXXXXXXXXXXILVLMASEI 3528
++P+ PEVFGLH NA I + ++ + L+ L + +A EI
Sbjct: 2728 ALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEI 2787
Query: 3529 LSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVM 3588
+K+P FD++ +K+ + + + VL+QE+ERFNKL+ + SL +LQ+A+ G + M
Sbjct: 2788 ENKMPKVFDLDQVRKRLGTGLSPT-SVVLLQELERFNKLVVRMTKSLAELQRALAGEVGM 2846
Query: 3589 SPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLP 3648
S LD + ++ +G IP WR+ + +LK L +++ F+ R S W +P WL
Sbjct: 2847 SNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLS 2906
Query: 3649 GFFFTQAFLTGSVQNYARAKTIPID---LLVFDFEIRNVDYETTPPKWGVFVQGLFMDGG 3705
G +++LT VQ R P+D L + ++ D G FV GL+++G
Sbjct: 2907 GLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGA 2966
Query: 3706 RWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHS 3765
W+ E + + PKVL ++P++ + P + ++ P+Y T R+ +
Sbjct: 2967 DWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGV---- 3022
Query: 3766 SNFVLAFYLPSDKPSAHWIKRSVALLLQLD 3795
V L + + +HW+ + V L L D
Sbjct: 3023 -GLVFEADLFTTRHISHWVLQGVCLTLNSD 3051
Score = 686 bits (1696), Expect = 0.0
Identities = 414/1143 (36%), Positives = 626/1143 (54%), Gaps = 94/1143 (8%)
Query: 837 EWIQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPI 896
E IQS LDD+ + GS FV PF V W + + + I+ W VQ +W+YL I
Sbjct: 12 EIIQS-LDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESI 70
Query: 897 FSSKDIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLEKI 956
F DI +Q+PEE F ++ +++R MG KDP + L + + LEK
Sbjct: 71 FIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKC 130
Query: 957 NDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFD---- 1012
+N+YL+ KR FPRFFF+S+DE+L IL + +PL VQ H+ K ++ I L F+
Sbjct: 131 QKSLNDYLDSKRNAFPRFFFISDDELLSILGSS-DPLCVQEHMIKMYDNIASLRFNDGDS 189
Query: 1013 GEFNISAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDY-PN 1071
GE +SAMIS EGE +EF ++ A G VE W+ V +M + + T+ + + Y +
Sbjct: 190 GEKLVSAMISAEGEVMEFRKIVR---AEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCED 246
Query: 1072 MGRVEWVLSWEGMVVLAISQIYWAVDVHESLNTHKLSELQAFHS---ELTKQLNETVAVI 1128
RV+W+L ++GMVVLA SQ++W +V + + + E QA + ++ +Q++E V I
Sbjct: 247 RSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRI 306
Query: 1129 RRTDLTKLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYV 1186
L+K +++IDVHA+D++ I+ + E +F W +QLR+YW+ E + +
Sbjct: 307 TMP-LSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNI 365
Query: 1187 KIINAVVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDL 1246
+ Y YEY+G + RLVITPLTDR Y TL A ++L GAP GPAGTGKTETTKDL
Sbjct: 366 RQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDL 425
Query: 1247 AKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW------------------------- 1281
AKAL + CVV NC +G+DY+A+GK F GLA CGAW
Sbjct: 426 AKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIR 485
Query: 1282 -AVRQHLETFDFEGTTLKLNPACYVCITMNPGYAGRSEL---------------PDNLKV 1325
A+ L TF FEG + L+ + ITMNPGYAGR+EL PD ++
Sbjct: 486 NALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQI 545
Query: 1326 ----LF-------RTVAM-MVPDYAMI-EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPN 1372
LF +T+A M Y + EQLS Q HYD+G+RA+K+VL AG LKR +
Sbjct: 546 CEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSD 605
Query: 1373 ESESVLLLRSITDVNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNN 1432
E V+L+R++ D+NLPKF+ DVPLF G+ISDLFPG+ P+ Y +F +A V E N
Sbjct: 606 LREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENG 665
Query: 1433 LQPMECFLIKVIQTYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECT 1492
+ + KV+Q +E M+ RH M+VG GKS+ + L +A + + G
Sbjct: 666 YAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTKL-------GLTTK 718
Query: 1493 YKVLNPKAVTMGQLYGAFDPISYEWTDGIVATMFREF-ASEDTPVRKWIVFDGPVDAVWI 1551
+LNPKAV++ +LYG DP + +WTDG+++ +FRE D RK+I+FDG VDA+W+
Sbjct: 719 LYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWV 778
Query: 1552 ENMNTVLDDNKKLCLTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFM 1611
ENMN+V+DDN+ L L +GE + + +++FEV DL ASPATVSRCGM+Y++ +L +
Sbjct: 779 ENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYR 838
Query: 1612 PFYKSWLNTLNPIWLEEN------EEYIYDMCDWLFDPLV-YYVRKFCGQLVTAGEVNLV 1664
P++K W+N + P +E+ E+Y+ + D + + +V + +V ++N+V
Sbjct: 839 PYWKKWVNQI-PNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMV 897
Query: 1665 ISTLRLVEMLMDNAIEGEEDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYF 1724
++++ L++ I ED +FL +L + LG L D R KFD+ +K
Sbjct: 898 TQLAKMLDALLEGEI---EDLDLLECYFLEALYCS----LGASLLEDGRMKFDEYIKRLA 950
Query: 1725 KGEKGIPSKIERIDVSIPAEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIP 1784
+ +P + + F+ + W W V + + ++
Sbjct: 951 SLSTVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVH 1010
Query: 1785 TLETEKFMYLLNLHSKYLKPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXS 1844
T++T + ++L K +P++ +G +GT K+ QNFL NL E + +
Sbjct: 1011 TVDTTRTTWILEQMVKIKQPVIFVGESGTSKTATTQNFL-KNLSEETNIVLMVNFSSRTT 1069
Query: 1845 ANQTQDLVISKLVKRRKNNYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKH 1904
+ Q + + + KR K+ YGP GK ++F+DDMNMP + YG Q I LL+L ++ +
Sbjct: 1070 SMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGY 1129
Query: 1905 WYD 1907
YD
Sbjct: 1130 LYD 1132
>AL096732-1|CAB46377.1| 965|Homo sapiens hypothetical protein
protein.
Length = 965
Score = 1014 bits (2511), Expect = 0.0
Identities = 476/969 (49%), Positives = 669/969 (69%), Gaps = 10/969 (1%)
Query: 2833 EFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAK 2892
E++ LG+N+IEY +F+LY+TT+LRNPHYLPE+ KV L+NF +T GL+DQ LGIV AK
Sbjct: 2 EYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAK 61
Query: 2893 ERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAID 2952
E+P+L+EK+ +LIV+ A N+ LK++ED IL L +KG+ILEDE+AI+VL SSK L+ +
Sbjct: 62 EKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEE 121
Query: 2953 IMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIIS 3012
I +KQ+ + TET I++ R+GY+P+A HSA +++C+++L N++PMYQYSLTWFINLY+ S
Sbjct: 122 ISEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHS 181
Query: 3013 IENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDE 3072
+ ++ KS++L R+K++ D FT ++Y+NVCRSLF+KDKL+FS ++ +M +++ +
Sbjct: 182 LTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEV 241
Query: 3073 YKFLITGGIAVENHLKKPV-EWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDD 3131
+ FL+TGGIA++N P +WL +KAW EI R + L + + + +W+ +YD
Sbjct: 242 WYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDS 301
Query: 3132 IEPQNKTLPGGWDERLTQ-FQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISK 3190
P + LPG W + +Q +K++++R LRPDK+ AV +F+ + MG+ Y P FD+
Sbjct: 302 AWPHEEQLPGSW--KFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQG 359
Query: 3191 SFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF-SHRFNSISLGQGQGPIARAMIEKAQ 3249
S+ DS+C APLIF+LSP +DPM L+K+ + +G R +ISLGQGQGPIA MI A
Sbjct: 360 SYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAI 419
Query: 3250 SEGGWVCLQNCHLAVSWLPVLEKIVEGFDL-TNTDLSFRLWLTSYPSDKFPQSVLQVGVK 3308
+G WV LQNCHLA SW+P LEKI E + +T+ FRLWLTSYPS+KFP S+LQ G+K
Sbjct: 420 KDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIK 479
Query: 3309 MTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGP 3368
MTNEPP GL+ NL RSY+++P+ +P F++ C K + K+L+G+ FFHAVVQER+ FGP
Sbjct: 480 MTNEPPKGLRANLLRSYLNDPISDPVFFQSC-AKAVMWQKMLFGLCFFHAVVQERRNFGP 538
Query: 3369 LGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVT 3428
LGWNI Y FN+SD +IS+ Q+QMFLN Y+E+ + A+ YLTGECNYGGRVTDD DRRL+++
Sbjct: 539 LGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLLLS 598
Query: 3429 ILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGI 3488
+L + + D Y G Y +P YQ Y+ ++ ++PI PEVFGLH NA I
Sbjct: 599 LLSMFYCKEIEED--YYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADI 656
Query: 3489 TRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPVD 3548
T+D + +L ++L ++ +A +ILSKLP FD+E K YPV
Sbjct: 657 TKDNQETNQLFEGVLLTLPRMSGGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVV 716
Query: 3549 YNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENW 3608
Y ESMNTVL QE+ RFN+L ++ SL +L +A+KG ++MS L+ N+ML+GK+P W
Sbjct: 717 YEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMW 776
Query: 3609 RKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAK 3668
SYPSLKPL YVAD + RL+ ++W G P FW+ GF+FTQ+FLTG QNYAR
Sbjct: 777 AAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKY 836
Query: 3669 TIPIDLLVFDFEIRNVD-YETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMP 3727
TIPID + F+FE+ + P+ G +++GLF++G RW+R+T I E LPK+L D +P
Sbjct: 837 TIPIDHIGFEFEVTPQETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLP 896
Query: 3728 VIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRS 3787
+IWL P F Y CP+YKT R+G L+TTGHS+N+VL+ LP+D P HWI R
Sbjct: 897 IIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRG 956
Query: 3788 VALLLQLDN 3796
VA L QLDN
Sbjct: 957 VASLCQLDN 965
>AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 4155 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4211
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4212 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4264
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4265 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4324
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4325 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4380
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4381 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4440
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4441 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4500
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4501 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4559
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4560 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4619
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4620 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4671
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4672 VYLRTVLSPDHWILRGVALLCDI 4694
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 4155 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4211
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4212 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4264
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4265 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4324
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4325 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4380
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4381 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4440
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4441 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4500
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4501 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4559
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4560 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4619
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4620 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4671
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4672 VYLRTVLSPDHWILRGVALLCDI 4694
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2639 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2698
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2699 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2755
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2756 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 2815
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 2816 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 2875
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 2876 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 2934
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 2935 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 2994
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 2995 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3054
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3055 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3114
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3115 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3174
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3175 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3233
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3234 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3292
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3293 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3352
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3353 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3412
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3413 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3472
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3473 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3531
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3532 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3591
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3592 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3651
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3652 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3711
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3712 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3771
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3772 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 3831
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 3832 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 3892 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 3949
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 3950 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4006
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4059
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4060 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4119
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4120 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4175
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4176 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4235
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4236 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4295
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4296 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4354
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4355 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4414
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4415 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4466
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4467 VYLRTVLSPDHWILRGVALLCDI 4489
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1397
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1398 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1457
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1458 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1517
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1637
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1638 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1694
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1695 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1753
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1754 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 1813
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 1814 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 1873
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 1874 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 1933
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 1934 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 1993
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 1994 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2053
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2054 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2113
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2114 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2166
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2226
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2227 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2283
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2284 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2342
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2343 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2390
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2391 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2449
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2450 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2508
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2509 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2568
Query: 1922 YGAI 1925
A+
Sbjct: 2569 IAAM 2572
>AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 4155 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4211
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4212 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4264
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4265 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4324
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4325 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4380
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4381 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4440
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4441 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4500
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4501 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4559
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4560 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4619
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4620 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4671
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4672 VYLRTVLSPDHWILRGVALLCDI 4694
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2639 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2698
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2699 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2755
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2756 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 2815
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 2816 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 2875
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 2876 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 2934
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 2935 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 2994
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 2995 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3054
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3055 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3114
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3115 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3174
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3175 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3233
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3234 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3292
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3293 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3352
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3353 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3412
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3413 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3472
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3473 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3531
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3532 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3591
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3592 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3651
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3652 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3711
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3712 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3771
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3772 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 3831
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 3832 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 3892 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 3949
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 3950 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4006
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4059
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4060 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4119
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4120 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4175
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4176 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4235
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4236 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4295
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4296 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4354
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4355 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4414
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4415 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4466
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4467 VYLRTVLSPDHWILRGVALLCDI 4489
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1397
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1398 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1457
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1458 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1517
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1637
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1638 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1694
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1695 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1753
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1754 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 1813
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 1814 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 1873
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 1874 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 1933
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 1934 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 1993
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 1994 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2053
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2054 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2113
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2114 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2166
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2226
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2227 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2283
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2284 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2342
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2343 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2390
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2391 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2449
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2450 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2508
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2509 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2568
Query: 1922 YGAI 1925
A+
Sbjct: 2569 IAAM 2572
>AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 4155 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4211
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4212 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4264
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4265 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4324
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4325 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4380
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4381 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4440
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4441 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4500
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4501 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4559
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4560 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4619
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4620 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4671
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4672 VYLRTVLSPDHWILRGVALLCDI 4694
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2639 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2698
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2699 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2755
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2756 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 2815
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 2816 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 2875
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 2876 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 2934
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 2935 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 2994
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 2995 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3054
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3055 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3114
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3115 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3174
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3175 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3233
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3234 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3292
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3293 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3352
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3353 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3412
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3413 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3472
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3473 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3531
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3532 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3591
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3592 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3651
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3652 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3711
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3712 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3771
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3772 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 3831
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 3832 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 3892 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 3949
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 3950 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4006
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4059
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4060 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4119
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4120 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4175
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4176 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4235
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4236 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4295
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4296 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4354
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4355 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4414
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4415 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4466
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4467 VYLRTVLSPDHWILRGVALLCDI 4489
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1397
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1398 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1457
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1458 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1517
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1637
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1638 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1694
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1695 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1753
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1754 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 1813
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 1814 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 1873
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 1874 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 1933
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 1934 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 1993
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 1994 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2053
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2054 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2113
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2114 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2166
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2226
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2227 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2283
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2284 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2342
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2343 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2390
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2391 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2449
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2450 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2508
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2509 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2568
Query: 1922 YGAI 1925
A+
Sbjct: 2569 IAAM 2572
>AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 4155 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4211
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4212 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4264
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4265 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4324
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4325 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4380
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4381 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4440
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4441 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4500
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4501 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4559
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4560 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4619
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4620 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4671
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4672 VYLRTVLSPDHWILRGVALLCDI 4694
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 1002 bits (2480), Expect = 0.0
Identities = 600/1883 (31%), Positives = 966/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2639 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2698
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2699 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2755
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2756 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 2815
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 2816 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 2875
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 2876 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 2934
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 2935 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 2994
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 2995 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3054
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3055 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3114
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3115 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3174
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3175 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3233
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3234 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3292
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3293 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3352
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3353 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3412
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3413 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3472
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3473 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3531
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3532 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3591
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3592 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3651
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3652 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3711
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3712 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3771
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3772 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 3831
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 3832 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 3892 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 3949
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 3950 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4006
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4059
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YGGR
Sbjct: 4060 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGR 4119
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4120 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4175
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4176 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4235
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4236 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD 4295
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4296 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4354
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4355 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4414
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4415 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4466
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4467 VYLRTVLSPDHWILRGVALLCDI 4489
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1397
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1398 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1457
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1458 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1517
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1637
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1638 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1694
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1695 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1753
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1754 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 1813
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 1814 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 1873
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 1874 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 1933
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 1934 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 1993
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 1994 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2053
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2054 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2113
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2114 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2166
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2226
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2227 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2283
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2284 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2342
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2343 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2390
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2391 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2449
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2450 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2508
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2509 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2568
Query: 1922 YGAI 1925
A+
Sbjct: 2569 IAAM 2572
>AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy chain
8 protein.
Length = 4490
Score = 999 bits (2473), Expect = 0.0
Identities = 599/1883 (31%), Positives = 965/1883 (51%), Gaps = 51/1883 (2%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2639 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2698
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2699 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2755
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2756 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 2815
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 2816 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 2875
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 2876 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 2934
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 2935 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 2994
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 2995 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3054
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3055 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3114
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3115 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3174
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3175 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3233
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3234 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3292
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3293 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3352
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3353 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3412
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3413 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3472
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3473 TQGKTWIKSKEKENDLQVTSLNRKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3531
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3532 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3591
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3592 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3651
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3652 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3711
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3712 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3771
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3772 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 3831
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 3832 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 3891
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 3892 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 3949
Query: 3243 AMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTN-TDLSFRLWLTSYPSDKFPQS 3301
+I+ + +GGWV LQNCHL L +E+++E T +D SFR+W+T+ P D+FP +
Sbjct: 3950 KLIQMSMQQGGWVLLQNCHLG---LEFMEELLETLITTEASDDSFRVWITTEPHDRFPIT 4006
Query: 3302 VLQVGVKMTNEPPTGLQHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAV 3359
+LQ +K TNEPP G++ L R++ I++ L + P + +LY ++F H+
Sbjct: 4007 LLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLD---ISNLP----MWKPMLYTVAFLHST 4059
Query: 3360 VQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGR 3416
VQER+KFGPLGWNI Y FN +DF SV +Q L++ + + + ++Y+ GE YG R
Sbjct: 4060 VQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGDR 4119
Query: 3417 VTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPP 3476
VTDD+D+RL+ + + + +P++ F Y +P Y ++I+S+P
Sbjct: 4120 VTDDFDKRLLNCFARVWFSEKMF-EPSFCFY---TGYKIPLCKTLDQYFEYIQSLPSLDN 4175
Query: 3477 PEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE-ILSKLPPK 3535
PEVFGLH NA IT + + + ++ + +V SE +LSKLPP
Sbjct: 4176 PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD 4235
Query: 3536 F-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDL 3594
+ E+ + + + SMN L QE++R ++++ ++SSL DL+ A++G I+MS L
Sbjct: 4236 YIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISVLRSSLSDLKLAIEGTIIMSENLRD 4295
Query: 3595 QSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQ 3654
+ M +IP+ W++ S+ S L + + +ER + W G+P FW+ GFF Q
Sbjct: 4296 ALDNMYDARIPQLWKRVSWDS-STLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQ 4354
Query: 3655 AFLTGSVQNYARA-KTIPIDLLVFDFEIRNVDYE--TTPPKWGVFVQGLFMDGGRWNRET 3711
FLT Q RA K +D + E+ E T+PP GV++ GL+MDG W+R
Sbjct: 4355 GFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRN 4414
Query: 3712 HAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLA 3771
+ E PKVL +PV+ ++ + Y CP+YK R + F+
Sbjct: 4415 GKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKKPRRTDL--------TFITV 4466
Query: 3772 FYLPSDKPSAHWIKRSVALLLQL 3794
YL + HWI R VALL +
Sbjct: 4467 VYLRTVLSPDHWILRGVALLCDI 4489
Score = 578 bits (1426), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1339 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1397
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1398 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1457
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1458 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1517
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1518 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1577
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1578 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHTKDYDRIMAVISREGE 1637
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1638 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1694
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1695 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1753
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1754 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 1813
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 1814 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 1873
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 1874 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 1933
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 1934 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 1993
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 1994 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2053
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2054 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2113
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2114 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2166
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2167 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2226
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2227 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2283
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2284 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2342
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2343 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2390
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2391 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2449
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2450 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2508
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2509 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2568
Query: 1922 YGAI 1925
A+
Sbjct: 2569 IAAM 2572
>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy chain
9 protein.
Length = 4486
Score = 997 bits (2467), Expect = 0.0
Identities = 604/1873 (32%), Positives = 958/1873 (51%), Gaps = 73/1873 (3%)
Query: 1941 PTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYDRLVDDQDRAW 2000
PT K HYIFNLRDF+ + QG E + I++++HE RV+ D++V+++D
Sbjct: 2668 PTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKD--- 2724
Query: 2001 FFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSAEGERRYEEIP 2060
F + K + +K TF+ +D + N+ Y + GE +Y +
Sbjct: 2725 -FDLFDKIQTEVLKKTFDDI----EDPVEQTQSPNL-------YCHFANGIGEPKYMPVQ 2772
Query: 2061 SKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGR 2120
S E+ V L +N ++ M +VLF+ A+ H+ I RIL P GNALLVGVGGSG+
Sbjct: 2773 SWELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 2831
Query: 2121 QSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEES 2180
QSLTRLA+ I VFQ + K Y ++D+ D+ + ++G N +T FL T++Q+ +E
Sbjct: 2832 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 2891
Query: 2181 YIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDISPLQILAFFVGRCKAKL 2240
++ ++ LL SGE+P+LY DE + I+ VR + ++ L + FF+ R + +L
Sbjct: 2892 FLVLINDLLASGEIPDLYSDDEVENIISNVRNEVK--SQGLVDNRENCWKFFIDRIRRQL 2949
Query: 2241 HIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSS 2300
+ LCFSP+G+ R R R +P++VNC I W+ WP+ ALE V+ ++ +P
Sbjct: 2950 KVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQ 3009
Query: 2301 AVIACKQF-HVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRY 2359
++ F H S + ++ R Y T S+L+ I+ + +L +R ++EL+ R
Sbjct: 3010 SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERL 3069
Query: 2360 TNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQ 2419
NGL +L + V ++ L A + +L E + K++Q + VET + A E++
Sbjct: 3070 ENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEE 3129
Query: 2420 KXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVM 2479
+ + +KDCE DLA A P L A AALNTL ++T +KS +PP V V
Sbjct: 3130 QKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVS 3189
Query: 2480 AAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDM-GFLDSLKNFDKDNIPVATMQK 2538
AAV V W +K + + GFLDSL NF+K+NI ++
Sbjct: 3190 AAVMVLMAPRGRVPKDRS---------WKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
Query: 2539 IRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQT 2598
IR YL + +F P VA S AA GLC W+I + +
Sbjct: 3241 IRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA 3299
Query: 2599 MAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEK 2658
L KA + K + E ++ + A +L+GGL E
Sbjct: 3300 QEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASEN 3359
Query: 2659 VRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WRDLV--IKLNMPH 2715
VRW A +N + L GDIL+ I+YL +T R ++D+ WR + +K +P
Sbjct: 3360 VRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPV 3419
Query: 2716 SEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTM 2775
+ +L D + W GLP D S++NA I N RW L++DPQ Q KWIK
Sbjct: 3420 TPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN- 3478
Query: 2776 EKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFI 2835
+ DL+V + Y+++IE LE G LI+ + E ++ L P+L + +G FI
Sbjct: 3479 KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFI 3536
Query: 2836 ALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERP 2895
+GD EY+P FRL + TKL NPHY PE+ + TLINF +T+DGLEDQ L VV+ ERP
Sbjct: 3537 KIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERP 3596
Query: 2896 DLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMK 2955
DL++ + L Q + LK +ED +L L G+ L + +E L+ +K A ++ K
Sbjct: 3597 DLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEK 3656
Query: 2956 KQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIEN 3015
K + + TE I + R YRP A+ +++LY+ + +L + PMYQ+SL F ++ ++E
Sbjct: 3657 KVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVER 3716
Query: 3016 ANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKF 3075
A + L +R+ L D+ T+++Y R LF+ DKL + + +++L ++N E F
Sbjct: 3717 AAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDF 3776
Query: 3076 LITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQ 3135
L+ V+ PVE+L +AW + L+ ++ F D + W++ + P+
Sbjct: 3777 LLRS--PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPE 3834
Query: 3136 NKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDS 3195
+ LP W + T Q+L ++R +RPD++T A+ F+E+++G KY D + SF +S
Sbjct: 3835 KEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEES 3893
Query: 3196 NCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQGQGPIARAMIEKAQSEG 3252
P+ FILSPG DP+ + ++G+ + F+++SLGQGQ +A A ++ A +G
Sbjct: 3894 GPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKG 3953
Query: 3253 GWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDK-----FPQSVLQVGV 3307
WV LQN HL WL LEK +E N+ FR+++++ P+ PQ +L+ +
Sbjct: 3954 HWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAEPAPSPEGHIIPQGILENSI 4012
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
K+TNEPPTG+ NL+++ + + E C ++ F +L+ + +FHAVV ER+KFG
Sbjct: 4013 KITNEPPTGMHANLHKALDN---FTQDTLEMC-SRETEFKSILFALCYFHAVVAERRKFG 4068
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
P GWN Y FN D ISV L FL ++ Y ++YL GE YGG +TDDWDRRL
Sbjct: 4069 PQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCR 4128
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
T L ++ ++ L + LP +Y Y ++I++ P ++GLH NA
Sbjct: 4129 TYLGEFIRPEMLEGE----LSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAE 4184
Query: 3488 ITRDYSISMELTSSLVLV---XXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKK 3544
I S +L +++ + + + EIL ++ +F++ K
Sbjct: 4185 IGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAK 4244
Query: 3545 YPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKI 3604
V+ V QE R N L EI+ SL++L+ +KG + M+ ++ NA+ +
Sbjct: 4245 --VEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMV 4302
Query: 3605 PENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQN-GKPPTFWLPGFFFTQAFLTGSVQN 3663
PE+W + +YPS L ++ D + R+ LE W + P T WL GFF Q+FLT +Q+
Sbjct: 4303 PESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4362
Query: 3664 YARAKTIPIDLLVF--DFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKV 3721
AR P+D + D +N + +PP+ G ++ GLFM+G W+ + I E K
Sbjct: 4363 TARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKD 4422
Query: 3722 LNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSA 3781
L MPV+++ ++ + + Y CP+YKT +R +V F L + + +
Sbjct: 4423 LTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR---------GPTYVWTFNLKTKENPS 4473
Query: 3782 HWIKRSVALLLQL 3794
W+ VALLLQ+
Sbjct: 4474 KWVLAGVALLLQI 4486
Score = 345 bits (847), Expect = 2e-93
Identities = 212/627 (33%), Positives = 319/627 (50%), Gaps = 59/627 (9%)
Query: 772 NPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLDQYEIISVAATKELALITNL 831
NPA+ +RHW ++ G T T+L ++ L D+ I A KE+ + L
Sbjct: 1378 NPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTL 1437
Query: 832 NKMMAEW-----------------------IQSVLDDHIVKTVGMRGSAFVKPFEAQVRT 868
++ W + VL+D+ V+ + S +V F +V
Sbjct: 1438 KELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSG 1497
Query: 869 WYEKIVRVNATIDEWGKVQSQWLYLLPIFS-SKDIVAQMPEEGVMFVEVNNIYRRYMGSV 927
W +K+ V+A I W +VQ W +L IF+ S+DI AQ+P++ F ++ ++
Sbjct: 1498 WQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDA 1557
Query: 928 DKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILS 987
K P+V++ G+ E L + YL+ KRL FPRF+FLS+ ++L+ILS
Sbjct: 1558 QKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILS 1617
Query: 988 ETKNPLKVQPHLKKCFEGINRLVFDGEFN---ISAMISMEGEQVEFLDMISVAAARGSVE 1044
P +VQ HL K F+ + ++ F + + + M ++ E++ G VE
Sbjct: 1618 NGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVE 1677
Query: 1045 KWLVQVEEQMLKAVKSETEISYYDYPNMGRVEWVLSWEGMVVLAISQIYWAVDVHES--- 1101
WL V M V+ E Y R +W+ V L +QI+W +V +
Sbjct: 1678 IWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFAR 1737
Query: 1102 LNTHKLSELQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAKDVISDLIKK 1161
L S ++ ++ + QL +T+ + L+K + + IDVHA+DV++ +I +
Sbjct: 1738 LEEGYESAMKDYYKKQVAQL-KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQ 1796
Query: 1162 KVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYLGNSDRLVITPLTDRCYRTL 1219
KV F WL+QLR+ W++E + I +A Y+YEYLGN+ RLVITPLTDRCY TL
Sbjct: 1797 KVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITL 1856
Query: 1220 IGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCG 1279
+ +L ++GAP GPAGTGKTETTKDL +AL + VFNCS+ +DYK+ G +KGLA G
Sbjct: 1857 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTG 1916
Query: 1280 AW--------------------------AVRQHLETFDFEGTTLKLNPACYVCITMNPGY 1313
AW A+R + F F G + LNP+ + ITMNPGY
Sbjct: 1917 AWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGY 1976
Query: 1314 AGRSELPDNLKVLFRTVAMMVPDYAMI 1340
AGR+ELP+NLK LFR AM+VPD+ +I
Sbjct: 1977 AGRTELPENLKSLFRPCAMVVPDFELI 2003
Score = 302 bits (741), Expect = 2e-80
Identities = 180/568 (31%), Positives = 292/568 (51%), Gaps = 25/568 (4%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
E LS Q+HYD+G+RA+K+VL AG+LKR P+ E +L+RS+ D N+PK ++ D+P+F
Sbjct: 2032 ELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFM 2091
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
G+I DLFP + +P+ NF + LQ + F++KV+Q E++ VRH +VG
Sbjct: 2092 GLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVG 2151
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
+GKS L+ L + ++ R + LNPKAVT +L+G +P + EW DG
Sbjct: 2152 GAGTGKSQVLRSLHKTYQIMKRRP-------VWTDLNPKAVTNDELFGIINPATGEWKDG 2204
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
+ +++ RE A+ KWI+ DG +D +WIE++NTV+DDNK L L S E + ++ M +
Sbjct: 2205 LFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKL 2264
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
+FE+ L A+PATVSR G++Y+ LG+ P SW+ ++ + + D
Sbjct: 2265 LFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKRE---IQTERANLTILFDKY 2321
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNA-IEGEEDTKYTRTWFLASLMTA 1699
+ +R +++ E ++V L+E L+ I + + +F + A
Sbjct: 2322 LPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYF----VFA 2377
Query: 1700 IVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDHFYMYKGKGC 1759
+W GG + D + D E+ K E V P++G + D++ + K
Sbjct: 2378 AIWAFGGAMVQD---QLVDYRAEFSKW-----WLTEFKTVKFPSQGTIFDYYIDPETKK- 2428
Query: 1760 WKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGPTGTGKSFYV 1819
++ W V + ++ L ++ T ET + Y + +P++L+G GTGKS V
Sbjct: 2429 FEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLV 2488
Query: 1820 QNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYGPTRGKHAIIFIDDM 1879
+ +LD E Y + ++ Q ++ L K+ NYGP K I FIDDM
Sbjct: 2489 -GAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDM 2547
Query: 1880 NMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
NMP + YG ++R + D HWYD
Sbjct: 2548 NMPEVDAYGTVQPHTIIRQHLDYGHWYD 2575
>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain 9
protein.
Length = 4486
Score = 997 bits (2467), Expect = 0.0
Identities = 604/1873 (32%), Positives = 958/1873 (51%), Gaps = 73/1873 (3%)
Query: 1941 PTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYDRLVDDQDRAW 2000
PT K HYIFNLRDF+ + QG E + I++++HE RV+ D++V+++D
Sbjct: 2668 PTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKD--- 2724
Query: 2001 FFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSAEGERRYEEIP 2060
F + K + +K TF+ +D + N+ Y + GE +Y +
Sbjct: 2725 -FDLFDKIQTEVLKKTFDDI----EDPVEQTQSPNL-------YCHFANGIGEPKYMPVQ 2772
Query: 2061 SKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGR 2120
S E+ V L +N ++ M +VLF+ A+ H+ I RIL P GNALLVGVGGSG+
Sbjct: 2773 SWELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 2831
Query: 2121 QSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEES 2180
QSLTRLA+ I VFQ + K Y ++D+ D+ + ++G N +T FL T++Q+ +E
Sbjct: 2832 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 2891
Query: 2181 YIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDISPLQILAFFVGRCKAKL 2240
++ ++ LL SGE+P+LY DE + I+ VR + ++ L + FF+ R + +L
Sbjct: 2892 FLVLINDLLASGEIPDLYSDDEVENIISNVRNEVK--SQGLVDNRENCWKFFIDRIRRQL 2949
Query: 2241 HIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSS 2300
+ LCFSP+G+ R R R +P++VNC I W+ WP+ ALE V+ ++ +P
Sbjct: 2950 KVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQ 3009
Query: 2301 AVIACKQF-HVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRY 2359
++ F H S + ++ R Y T S+L+ I+ + +L +R ++EL+ R
Sbjct: 3010 SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERL 3069
Query: 2360 TNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQ 2419
NGL +L + V ++ L A + +L E + K++Q + VET + A E++
Sbjct: 3070 ENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEE 3129
Query: 2420 KXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVM 2479
+ + +KDCE DLA A P L A AALNTL ++T +KS +PP V V
Sbjct: 3130 QKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVS 3189
Query: 2480 AAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDM-GFLDSLKNFDKDNIPVATMQK 2538
AAV V W +K + + GFLDSL NF+K+NI ++
Sbjct: 3190 AAVMVLMAPRGRVPKDRS---------WKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
Query: 2539 IRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQT 2598
IR YL + +F P VA S AA GLC W+I + +
Sbjct: 3241 IRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA 3299
Query: 2599 MAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEK 2658
L KA + K + E ++ + A +L+GGL E
Sbjct: 3300 QEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASEN 3359
Query: 2659 VRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WRDLV--IKLNMPH 2715
VRW A +N + L GDIL+ I+YL +T R ++D+ WR + +K +P
Sbjct: 3360 VRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPV 3419
Query: 2716 SEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTM 2775
+ +L D + W GLP D S++NA I N RW L++DPQ Q KWIK
Sbjct: 3420 TPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN- 3478
Query: 2776 EKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFI 2835
+ DL+V + Y+++IE LE G LI+ + E ++ L P+L + +G FI
Sbjct: 3479 KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFI 3536
Query: 2836 ALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERP 2895
+GD EY+P FRL + TKL NPHY PE+ + TLINF +T+DGLEDQ L VV+ ERP
Sbjct: 3537 KIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERP 3596
Query: 2896 DLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMK 2955
DL++ + L Q + LK +ED +L L G+ L + +E L+ +K A ++ K
Sbjct: 3597 DLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEK 3656
Query: 2956 KQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIEN 3015
K + + TE I + R YRP A+ +++LY+ + +L + PMYQ+SL F ++ ++E
Sbjct: 3657 KVQEAKVTEVKINEAREHYRPTAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVER 3716
Query: 3016 ANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKF 3075
A + L +R+ L D+ T+++Y R LF+ DKL + + +++L ++N E F
Sbjct: 3717 AAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDF 3776
Query: 3076 LITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQ 3135
L+ V+ PVE+L +AW + L+ ++ F D + W++ + P+
Sbjct: 3777 LLRS--PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPE 3834
Query: 3136 NKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDS 3195
+ LP W + T Q+L ++R +RPD++T A+ F+E+++G KY D + SF +S
Sbjct: 3835 KEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEES 3893
Query: 3196 NCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQGQGPIARAMIEKAQSEG 3252
P+ FILSPG DP+ + ++G+ + F+++SLGQGQ +A A ++ A +G
Sbjct: 3894 GPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKG 3953
Query: 3253 GWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDK-----FPQSVLQVGV 3307
WV LQN HL WL LEK +E N+ FR+++++ P+ PQ +L+ +
Sbjct: 3954 HWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAEPAPSPEGHIIPQGILENSI 4012
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
K+TNEPPTG+ NL+++ + + E C ++ F +L+ + +FHAVV ER+KFG
Sbjct: 4013 KITNEPPTGMHANLHKALDN---FTQDTLEMC-SRETEFKSILFALCYFHAVVAERRKFG 4068
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
P GWN Y FN D ISV L FL ++ Y ++YL GE YGG +TDDWDRRL
Sbjct: 4069 PQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCR 4128
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
T L ++ ++ L + LP +Y Y ++I++ P ++GLH NA
Sbjct: 4129 TYLGEFIRPEMLEGE----LSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAE 4184
Query: 3488 ITRDYSISMELTSSLVLV---XXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKK 3544
I S +L +++ + + + EIL ++ +F++ K
Sbjct: 4185 IGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAK 4244
Query: 3545 YPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKI 3604
V+ V QE R N L EI+ SL++L+ +KG + M+ ++ NA+ +
Sbjct: 4245 --VEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMV 4302
Query: 3605 PENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQN-GKPPTFWLPGFFFTQAFLTGSVQN 3663
PE+W + +YPS L ++ D + R+ LE W + P T WL GFF Q+FLT +Q+
Sbjct: 4303 PESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4362
Query: 3664 YARAKTIPIDLLVF--DFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKV 3721
AR P+D + D +N + +PP+ G ++ GLFM+G W+ + I E K
Sbjct: 4363 TARKNEWPLDQIALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKD 4422
Query: 3722 LNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSA 3781
L MPV+++ ++ + + Y CP+YKT +R +V F L + + +
Sbjct: 4423 LTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR---------GPTYVWTFNLKTKENPS 4473
Query: 3782 HWIKRSVALLLQL 3794
W+ VALLLQ+
Sbjct: 4474 KWVLAGVALLLQI 4486
Score = 345 bits (847), Expect = 2e-93
Identities = 212/627 (33%), Positives = 319/627 (50%), Gaps = 59/627 (9%)
Query: 772 NPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLDQYEIISVAATKELALITNL 831
NPA+ +RHW ++ G T T+L ++ L D+ I A KE+ + L
Sbjct: 1378 NPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTL 1437
Query: 832 NKMMAEW-----------------------IQSVLDDHIVKTVGMRGSAFVKPFEAQVRT 868
++ W + VL+D+ V+ + S +V F +V
Sbjct: 1438 KELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSG 1497
Query: 869 WYEKIVRVNATIDEWGKVQSQWLYLLPIFS-SKDIVAQMPEEGVMFVEVNNIYRRYMGSV 927
W +K+ V+A I W +VQ W +L IF+ S+DI AQ+P++ F ++ ++
Sbjct: 1498 WQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDA 1557
Query: 928 DKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILS 987
K P+V++ G+ E L + YL+ KRL FPRF+FLS+ ++L+ILS
Sbjct: 1558 QKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILS 1617
Query: 988 ETKNPLKVQPHLKKCFEGINRLVFDGEFN---ISAMISMEGEQVEFLDMISVAAARGSVE 1044
P +VQ HL K F+ + ++ F + + + M ++ E++ G VE
Sbjct: 1618 NGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVE 1677
Query: 1045 KWLVQVEEQMLKAVKSETEISYYDYPNMGRVEWVLSWEGMVVLAISQIYWAVDVHES--- 1101
WL V M V+ E Y R +W+ V L +QI+W +V +
Sbjct: 1678 IWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFAR 1737
Query: 1102 LNTHKLSELQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAKDVISDLIKK 1161
L S ++ ++ + QL +T+ + L+K + + IDVHA+DV++ +I +
Sbjct: 1738 LEEGYESAMKDYYKKQVAQL-KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQ 1796
Query: 1162 KVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYLGNSDRLVITPLTDRCYRTL 1219
KV F WL+QLR+ W++E + I +A Y+YEYLGN+ RLVITPLTDRCY TL
Sbjct: 1797 KVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITL 1856
Query: 1220 IGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCG 1279
+ +L ++GAP GPAGTGKTETTKDL +AL + VFNCS+ +DYK+ G +KGLA G
Sbjct: 1857 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTG 1916
Query: 1280 AW--------------------------AVRQHLETFDFEGTTLKLNPACYVCITMNPGY 1313
AW A+R + F F G + LNP+ + ITMNPGY
Sbjct: 1917 AWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGY 1976
Query: 1314 AGRSELPDNLKVLFRTVAMMVPDYAMI 1340
AGR+ELP+NLK LFR AM+VPD+ +I
Sbjct: 1977 AGRTELPENLKSLFRPCAMVVPDFELI 2003
Score = 301 bits (740), Expect = 2e-80
Identities = 180/568 (31%), Positives = 292/568 (51%), Gaps = 25/568 (4%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
E LS Q+HYD+G+RA+K+VL AG+LKR P+ E +L+RS+ D N+PK ++ D+P+F
Sbjct: 2032 ELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFM 2091
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
G+I DLFP + +P+ NF + LQ + F++KV+Q E++ VRH +VG
Sbjct: 2092 GLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVG 2151
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
+GKS L+ L + ++ R + LNPKAVT +L+G +P + EW DG
Sbjct: 2152 GAGTGKSQVLRSLHKTYQIMKRRP-------VWTDLNPKAVTNDELFGIINPATGEWKDG 2204
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
+ +++ RE A+ KWI+ DG +D +WIE++NTV+DDNK L L S E + ++ M +
Sbjct: 2205 LFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKL 2264
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
+FE+ L A+PATVSR G++Y+ LG+ P SW+ ++ + + D
Sbjct: 2265 LFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKRE---IQTERANLTILFDKY 2321
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNA-IEGEEDTKYTRTWFLASLMTA 1699
+ +R +++ E ++V L+E L+ I + + +F + A
Sbjct: 2322 LPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYF----VFA 2377
Query: 1700 IVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDHFYMYKGKGC 1759
+W GG + D + D E+ K E V P++G + D++ + K
Sbjct: 2378 AIWAFGGAMVQD---QLVDYRAEFSKW-----WLTEFKTVKFPSQGTIFDYYIDPETKK- 2428
Query: 1760 WKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGPTGTGKSFYV 1819
++ W V + ++ L ++ T ET + Y + +P++L+G GTGKS V
Sbjct: 2429 FEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLV 2488
Query: 1820 QNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYGPTRGKHAIIFIDDM 1879
+ +LD E Y + ++ Q ++ L K+ NYGP K I FIDDM
Sbjct: 2489 -GAKLASLDPEAYLVKNLPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDM 2547
Query: 1880 NMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
NMP + YG ++R + D HWYD
Sbjct: 2548 NMPEVDAYGTVQPHTIIRQHLDYGHWYD 2575
>AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1
protein.
Length = 1964
Score = 993 bits (2457), Expect = 0.0
Identities = 475/1034 (45%), Positives = 677/1034 (65%), Gaps = 7/1034 (0%)
Query: 2649 KLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLV 2708
+LI GL EKVRW ENLQ + +N++GD+LV+ G +AYL P+T R + D W +
Sbjct: 889 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 948
Query: 2709 IKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQA 2768
N+PH+ + LG +KI++W IAGLP D S++N +I S RW+ IDPQ QA
Sbjct: 949 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 1008
Query: 2769 NKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYL 2828
NKWIK MEK N L V K +D ++++ +E + +GKP L++ V E+++ L+PVLLK TY
Sbjct: 1009 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 1068
Query: 2829 QGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGI 2888
Q G + LGD VI YH +FR+Y+TTKL NPHY PEI K+TLINF L+ GLEDQ LG
Sbjct: 1069 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 1128
Query: 2889 VVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKN 2948
VVA+ERPDL+E + +LI+ A R LK +ED IL L ++G+ ++D I+VL++SK
Sbjct: 1129 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 1188
Query: 2949 LAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINL 3008
A +I K + +TE I+ R+ Y P+A + +L++CV++L NVDPMYQYSL WF+N+
Sbjct: 1189 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 1248
Query: 3009 YIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKM 3068
++ I N+ ++ +L+KR+ + TY+LYSNVCRSLF+K KLMF+F++C ++M++ K+
Sbjct: 1249 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 1308
Query: 3069 NVDEYKFLITGG-IAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQE 3127
N E+++L++GG I++ P +WL D+AW +I L++L F +F DFVK + +++
Sbjct: 1309 NQSEWRYLLSGGSISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRV 1367
Query: 3128 VYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFD 3187
++D +EP + LPG WD+ L QFQKLLV+R LR DK+T A+ F+ + ++ P +
Sbjct: 1368 IFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTAN 1427
Query: 3188 ISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEK 3247
+S F DSN PLIF+LSPG+DP L K+ E M FS + ++ISLGQGQGP A AM+
Sbjct: 1428 LSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRS 1487
Query: 3248 AQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGV 3307
+ G WV QNCHLA SW+P LE+++E + FRLWLTS PS+KFP S+LQ G
Sbjct: 1488 SIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGS 1547
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
KMT EPP G++ NL +SY S L E +F C K F LL + FH ER+KFG
Sbjct: 1548 KMTIEPPRGVRANLLKSYSS--LGE-DFLNSC-HKVMEFKSLLLSLCLFHGNALERRKFG 1603
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
PLG+NI Y F D D +I + QL+MFL++Y++I Y +KY GE NYGGRVTDDWDRR I+
Sbjct: 1604 PLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIM 1663
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
IL+++ N V++ P + + G + +P + YL +I+S+P+N PE+FGLH NA
Sbjct: 1664 NILEDFYNPDVLS-PEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 1722
Query: 3488 ITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPV 3547
IT + + L +++ + I+ + IL K+P +++ KYPV
Sbjct: 1723 ITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPV 1782
Query: 3548 DYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPEN 3607
Y ESMNTVL+QE+ R+N+LL I +LQDL KA+KGL+VMS L+L + ++ +PE
Sbjct: 1783 LYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPEL 1842
Query: 3608 WRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARA 3667
W +YPSLKPL S+V D ++RL L+ W Q+G P FW+ GFFF QAFLTG++QN+AR
Sbjct: 1843 WSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARK 1902
Query: 3668 KTIPIDLLVFDFEI 3681
I ID + FDF++
Sbjct: 1903 FVISIDTISFDFKV 1916
Score = 456 bits (1123), Expect = e-127
Identities = 253/730 (34%), Positives = 399/730 (54%), Gaps = 24/730 (3%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
+ AT +Y L PTPAKSHY FNLRD S+V QG + +++ +++W HE
Sbjct: 116 VEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHEN 175
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
RVF DRLV+++DR+WF +LK+ + + TF + +++G +
Sbjct: 176 CRVFRDRLVNEEDRSWFDQLLKRCMEQW-EVTFNKVCP-------------FQPILYGDF 221
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
+ S + YE I S+ + + + +YN ++ AK+ +VLF A+ H+ +I R L
Sbjct: 222 MSPGS--DVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLR 279
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
GNALL+GVGGSGR SLTRLAS + + FQ E++K+Y + +W DD+K VL ++G N
Sbjct: 280 QALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQN 339
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
TFLF+++QIK ES++++++++LNSG++PNLY DE+ +I+ +R Q + L +
Sbjct: 340 LPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQ--EQGLQPT 397
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
++A + GR ++ +H+VLC SPIG FR RLR +PSLVNCCTIDW++ WP +AL+ VA
Sbjct: 398 KANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVA 457
Query: 2285 HHYMVKVNVPDPVK---SSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSF 2341
++ ++ + + + C H I++ R Y+T SYL+L+ F
Sbjct: 458 TVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIF 517
Query: 2342 TTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEI 2401
+ L +K+ EL+ AK R +GLD+L + ++ VA MQ DL ++ P L A+ + M++I
Sbjct: 518 SILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQI 577
Query: 2402 EVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPAD 2461
+V+TAIA++ V+ ++ + D + DL ALP L+ A+A+L L D
Sbjct: 578 KVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKND 637
Query: 2462 ITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMG-FL 2520
+T V++M+ PP VKLV+ AVC+ + D+W P K +L D G FL
Sbjct: 638 VTEVRAMQRPPPGVKLVIEAVCI-MKGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFL 696
Query: 2521 DSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXX 2580
+SL FDKDNI ++ I + Y+ N++F+P +AK S A +C+W+ AM Y
Sbjct: 697 ESLFKFDKDNIGDVVIKAI-QPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKA 755
Query: 2581 XXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLC 2640
T IL+E K + KK+ LE + + C
Sbjct: 756 VEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQC 815
Query: 2641 IDKLFRAEKL 2650
+L RA K+
Sbjct: 816 EQRLGRAGKV 825
Score = 43.6 bits (98), Expect = 0.014
Identities = 19/29 (65%), Positives = 20/29 (68%)
Query: 1881 MPAKEVYGAQPAIELLRLYFDQKHWYDLK 1909
MPA E YGAQP IELLR + D WYD K
Sbjct: 1 MPALETYGAQPPIELLRQWMDHGGWYDRK 29
>AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein.
Length = 1457
Score = 993 bits (2457), Expect = 0.0
Identities = 475/1034 (45%), Positives = 677/1034 (65%), Gaps = 7/1034 (0%)
Query: 2649 KLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLV 2708
+LI GL EKVRW ENLQ + +N++GD+LV+ G +AYL P+T R + D W +
Sbjct: 382 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYDSWVKQL 441
Query: 2709 IKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQA 2768
N+PH+ + LG +KI++W IAGLP D S++N +I S RW+ IDPQ QA
Sbjct: 442 RSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQA 501
Query: 2769 NKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYL 2828
NKWIK MEK N L V K +D ++++ +E + +GKP L++ V E+++ L+PVLLK TY
Sbjct: 502 NKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYK 561
Query: 2829 QGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGI 2888
Q G + LGD VI YH +FR+Y+TTKL NPHY PEI K+TLINF L+ GLEDQ LG
Sbjct: 562 QQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQ 621
Query: 2889 VVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKN 2948
VVA+ERPDL+E + +LI+ A R LK +ED IL L ++G+ ++D I+VL++SK
Sbjct: 622 VVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKM 681
Query: 2949 LAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINL 3008
A +I K + +TE I+ R+ Y P+A + +L++CV++L NVDPMYQYSL WF+N+
Sbjct: 682 KAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNI 741
Query: 3009 YIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKM 3068
++ I N+ ++ +L+KR+ + TY+LYSNVCRSLF+K KLMF+F++C ++M++ K+
Sbjct: 742 FLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKI 801
Query: 3069 NVDEYKFLITGG-IAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQE 3127
N E+++L++GG I++ P +WL D+AW +I L++L F +F DFVK + +++
Sbjct: 802 NQSEWRYLLSGGSISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRV 860
Query: 3128 VYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFD 3187
++D +EP + LPG WD+ L QFQKLLV+R LR DK+T A+ F+ + ++ P +
Sbjct: 861 IFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTAN 920
Query: 3188 ISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEK 3247
+S F DSN PLIF+LSPG+DP L K+ E M FS + ++ISLGQGQGP A AM+
Sbjct: 921 LSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRS 980
Query: 3248 AQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGV 3307
+ G WV QNCHLA SW+P LE+++E + FRLWLTS PS+KFP S+LQ G
Sbjct: 981 SIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGS 1040
Query: 3308 KMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFG 3367
KMT EPP G++ NL +SY S L E +F C K F LL + FH ER+KFG
Sbjct: 1041 KMTIEPPRGVRANLLKSYSS--LGE-DFLNSC-HKVMEFKSLLLSLCLFHGNALERRKFG 1096
Query: 3368 PLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIV 3427
PLG+NI Y F D D +I + QL+MFL++Y++I Y +KY GE NYGGRVTDDWDRR I+
Sbjct: 1097 PLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIM 1156
Query: 3428 TILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAG 3487
IL+++ N V++ P + + G + +P + YL +I+S+P+N PE+FGLH NA
Sbjct: 1157 NILEDFYNPDVLS-PEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNAN 1215
Query: 3488 ITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPV 3547
IT + + L +++ + I+ + IL K+P +++ KYPV
Sbjct: 1216 ITFAQNETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPV 1275
Query: 3548 DYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPEN 3607
Y ESMNTVL+QE+ R+N+LL I +LQDL KA+KGL+VMS L+L + ++ +PE
Sbjct: 1276 LYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPEL 1335
Query: 3608 WRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARA 3667
W +YPSLKPL S+V D ++RL L+ W Q+G P FW+ GFFF QAFLTG++QN+AR
Sbjct: 1336 WSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARK 1395
Query: 3668 KTIPIDLLVFDFEI 3681
I ID + FDF++
Sbjct: 1396 FVISIDTISFDFKV 1409
Score = 163 bits (396), Expect = 1e-38
Identities = 102/319 (31%), Positives = 159/319 (49%), Gaps = 3/319 (0%)
Query: 2333 SYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAE 2392
SYL+L+ F+ L +K+ EL+ AK R +GLD+L + ++ VA MQ DL ++ P L A+
Sbjct: 2 SYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAAK 61
Query: 2393 KSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIA 2452
+ M++I+V+TAIA++ V+ ++ + D + DL ALP L+ A+A
Sbjct: 62 DTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALA 121
Query: 2453 ALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKR 2512
+L L D+T V++M+ PP VKLV+ AVC+ + D+W P K
Sbjct: 122 SLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCI-MKGIKPKKVPGEKPGTKVDDYWEPGKG 180
Query: 2513 ILGDMG-FLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAM 2571
+L D G FL+SL FDKDNI ++ I + Y+ N++F+P +AK S A +C+W+ AM
Sbjct: 181 LLQDPGHFLESLFKFDKDNIGDVVIKAI-QPYIDNEEFQPATIAKVSKACTSICQWVRAM 239
Query: 2572 DMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKK 2631
Y T IL+E K + KK+
Sbjct: 240 HKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKE 299
Query: 2632 ALEDEVQLCIDKLFRAEKL 2650
LE + + C +L RA K+
Sbjct: 300 ELELKCEQCEQRLGRAGKV 318
>AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy chain
dynein type 11 protein.
Length = 4523
Score = 964 bits (2387), Expect = 0.0
Identities = 594/1889 (31%), Positives = 969/1889 (51%), Gaps = 76/1889 (4%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
I AT + N PT K HYIFNLRD S V QG E I +W+HE
Sbjct: 2690 IQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHES 2749
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
RV+ D+L+D KK F + E+A + ++ G + +++ + C+
Sbjct: 2750 ARVYGDKLID-----------KKDCDLFQRRMLETAYKYFE---GIDSHMLLQQPLIYCH 2795
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
D + + Y + EV I L YN ++ A M +VLF+ A++H+ +I RIL
Sbjct: 2796 F-ADRGK-DPHYMPVKDWEVLKTILTETLDNYNELNAA-MHLVLFEDAMQHVCRISRILR 2852
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
P G ALLVGVGGSG+QSL+RLA+ + G +VFQ +T+ Y +++ D+ + +G N
Sbjct: 2853 TPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKN 2912
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
T FL T++Q+ +ES++ ++ LL SGE+P+L+ ++ +I+ + + S
Sbjct: 2913 MPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHA--LGMVDS 2970
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
FF+ R + +L I+LCFSP+G + R R R +P++VNC IDW+ +WP++AL V+
Sbjct: 2971 RENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVS 3030
Query: 2285 HHYMVKVNVPDPV-KSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTT 2343
++ + +PV K S + H +S ++ + R Y T S+L+ I F
Sbjct: 3031 RRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKN 3090
Query: 2344 LTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEV 2403
L +KQ E+ K R NG+ +L A V ++ L + + +L + + ++ +I +
Sbjct: 3091 LLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGL 3150
Query: 2404 ETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADIT 2463
+T + +++ + +++CEADL A P L A AALNTL +++
Sbjct: 3151 QTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLS 3210
Query: 2464 IVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMG-FLDS 2522
+K+ NPP V V AAV V W +K +G + FL +
Sbjct: 3211 ELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRS---------WKAAKVFMGKVDDFLQA 3261
Query: 2523 LKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWII-AMDMYDXXXXXX 2581
L N+DK++IP ++ + + YL + +F P+++ S AA GLC W+I + Y+
Sbjct: 3262 LINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVE 3321
Query: 2582 XXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCI 2641
T + +K +V +K ++EV
Sbjct: 3322 PKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKAT-AEKVRCQEEVNQTN 3380
Query: 2642 DKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII 2701
+ A +L+ L +K+RW + ++ + L GD+L++ ++Y+ P+T R E++
Sbjct: 3381 KTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELV 3440
Query: 2702 D-KWRD-LVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWS 2759
KW L K+++P +E +L D I W GLP D S +NA I + RW
Sbjct: 3441 HCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWP 3500
Query: 2760 LLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLD 2819
L+IDPQ Q KWIK + DL+V ++ IET L +G LI+ + E ++ LD
Sbjct: 3501 LVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLD 3559
Query: 2820 PVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKD 2879
P+L + T +G ++I +GD E++ NFRL + TKL NPHY PE+ + TL+NF +T+D
Sbjct: 3560 PLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTED 3617
Query: 2880 GLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESA 2939
GLE Q L VV+ ERPDL++ + L + LK +EDD+L L +G L+D
Sbjct: 3618 GLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKL 3677
Query: 2940 IEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQ 2999
+E L+++K +I K + E E I + R YRP+A+ +++LY+ + +L ++P+YQ
Sbjct: 3678 VERLEATKTTVAEIEHKVIEAKENERKINEARECYRPLAARASLLYFVINDLQKINPLYQ 3737
Query: 3000 YSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCS 3059
+SL F L+ +IE A+K +D++ R+ L ++ T+ ++ ++LF+KDKL F M
Sbjct: 3738 FSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAF 3797
Query: 3060 KMMLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFV 3119
+++L ++++ E FL+ VE+ PV++L ++W I + ++ FR D
Sbjct: 3798 QILLRKKEIDPLELDFLLR--FTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVE 3855
Query: 3120 KTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRK 3179
+ +W++ + P+ + LP W ++ + QKL+++R +RPD++T A+ F+E+++G K
Sbjct: 3856 GSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALRNFVEEKLGAK 3914
Query: 3180 YTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQG 3236
Y D+ K+F +S+ P+ FILSPG D + L +R+GF S +F+++SLGQG
Sbjct: 3915 YVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQG 3974
Query: 3237 QGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLT--SYP 3294
Q +A +EKA G WV LQN HL WL LEK++E F + +R++++ S P
Sbjct: 3975 QETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFS-QGSHRDYRVFMSAESAP 4033
Query: 3295 SDK---FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLY 3351
+ PQ +L+ +K+TNEPPTG+ NL+ + + + + E C K++ F +L+
Sbjct: 4034 TPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---FDQDTLEIC-SKEQEFKSILF 4089
Query: 3352 GISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGEC 3411
+ +FHA V R +FGP GW+ Y FN D I L +L ++ + ++YL GE
Sbjct: 4090 SLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEI 4149
Query: 3412 NYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESV 3471
YGG +TDDWDR+L L+ +VN + D L + P +Y Y ++IE +
Sbjct: 4150 MYGGHITDDWDRKLCRVYLEEFVNPSLTEDE----LMLAPGFAAPPYLDYAGYHQYIEEM 4205
Query: 3472 PINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXXXXXILVLMASEI 3528
P ++GLH NA I S L +L+ + + + +I
Sbjct: 4206 LPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDI 4265
Query: 3529 LSKLPPKFDV-EIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIV 3587
L KLP +F++ EI QK V QE ER N L+ EI+ SL+ L ++KG +
Sbjct: 4266 LEKLPEEFNMAEIMQKN---SNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELA 4322
Query: 3588 MSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQN-GKPPTFW 3646
+SPA++ Q A+ +P+ W K +YPS L + D + R L+ W Q+ P W
Sbjct: 4323 LSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVW 4382
Query: 3647 LPGFFFTQAFLTGSVQNYARAKTIPID--LLVFDFEIRNVDYETTPPKWGVFVQGLFMDG 3704
L GFF Q+FLT +Q AR P+D L D + + PP+ G ++ GLFM+G
Sbjct: 4383 LSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEG 4442
Query: 3705 GRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGH 3764
RW+ + I E K L MPVI+ + Y+CP+Y+T R
Sbjct: 4443 ARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR--------- 4493
Query: 3765 SSNFVLAFYLPSDKPSAHWIKRSVALLLQ 3793
+++ F L S++ +A W+ VALLL+
Sbjct: 4494 GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
Score = 548 bits (1353), Expect = e-154
Identities = 385/1248 (30%), Positives = 605/1248 (48%), Gaps = 123/1248 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLDQYEI 816
+KD +++ + +PAL RHW ++ G T+L ++ L D
Sbjct: 1392 VKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRR 1451
Query: 817 ISVAATKELA---LITNLNKMMA--------------------EWIQSVLDDHIVKTVGM 853
I A KEL +IT +++ A E + L+ + V+ +
Sbjct: 1452 IVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTL 1511
Query: 854 RGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIF-SSKDIVAQMPEEGVM 912
S +V+ F QV +W K+ + I W +VQ W +L IF S+DI Q+ ++
Sbjct: 1512 LQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARR 1571
Query: 913 FVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFP 972
F V+ ++ M K +VLE + E + + L + YLE KR+ FP
Sbjct: 1572 FDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFP 1631
Query: 973 RFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEFNISA--MISMEGEQVEF 1030
RF+F+S+ ++L+ILS+ P +V HL K F+ I L F+ ++SA + M ++ E+
Sbjct: 1632 RFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEY 1691
Query: 1031 LDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGRVEWVLSWEGMVVLAIS 1090
+ + G VE WL+Q+E+ M + V+ + Y R W+ + V L S
Sbjct: 1692 VPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSS 1751
Query: 1091 QIYWAVDV---HESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVI 1147
QI+W DV L + L+ FH + QLN T+ + +L + + I
Sbjct: 1752 QIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLN-TLITLLLGELPPGDRQKIMTICTI 1810
Query: 1148 DVHAKDVISDLIKKKVTEVTD--FQWLAQLRYYWEE--ERVYVKIINAVVHYAYEYLGNS 1203
DVHA+DV++ LI +K V+ F WL+QLR+ WE+ + +V I +A Y YEYLGNS
Sbjct: 1811 DVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNS 1870
Query: 1204 DRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGL 1263
RLVITPLTDRCY TL + +L ++GAP GPAGTGKTETTKDL +AL + VFNCS+ +
Sbjct: 1871 PRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQM 1930
Query: 1264 DYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDFEGTTL 1297
DYK++G +KGL GAW A+R + F F G +
Sbjct: 1931 DYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAI 1990
Query: 1298 KLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQ--LSSQNHYDYGMRA 1355
L P+ + ITMNPGYAGR+ELP+NLK LFR AM+ PD +I + L ++ D A
Sbjct: 1991 TLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALA 2050
Query: 1356 VK--TVLSAAGNLKRSFPNESESVLLLRSIT---------DVNLPK-------FLSFDVP 1397
K T+ + L + + ++S+ D N P+ F++P
Sbjct: 2051 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMP 2110
Query: 1398 --------LFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEM 1449
+F G++ DLFP + +P+ +F LQP E F++KV+Q E+
Sbjct: 2111 KIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEEL 2170
Query: 1450 MIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGA 1509
+ VRH +VGN +GKS L+ L+ + ++ + +P + LNPKAVT +L+G
Sbjct: 2171 LAVRHSVFVVGNAGTGKSKILRTLNR--TYVNMKQKP-----VWNDLNPKAVTTDELFGF 2223
Query: 1510 FDPISYEWTD---------GIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDD 1560
+ EW D G+ +++ RE A+ KWIV DG +D +WIE++NTV+DD
Sbjct: 2224 IHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDD 2283
Query: 1561 NKKLCLTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNT 1620
NK L L S E +A++ M ++FE+ L A+PATVSR G++Y+ LG+ P+ SW++
Sbjct: 2284 NKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDR 2343
Query: 1621 LNPIWLEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVE-MLMDNAI 1679
+ N ++D + +R + + E +LV + L+E +L +
Sbjct: 2344 RRHQSEKANLTILFDK---YVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENV 2400
Query: 1680 EGEEDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDV 1739
+ + +F + A +W GG L D + +++ E V
Sbjct: 2401 PSDSPKEVYEVYF----VFACIWAFGGTLLQDQISDYQADFSRWWQKEMKA--------V 2448
Query: 1740 SIPAEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHS 1799
P++G + D++ +K K W D + + + L ++ T ET + Y + L
Sbjct: 2449 KFPSQGTIFDYYVDHKTKKL-LPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLL 2507
Query: 1800 KYLKPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKR 1859
+ KPL+L+G G GK+ +V + L + E Y + ++ Q ++ L K+
Sbjct: 2508 EKGKPLMLVGNAGVGKTVFVGDTLASL--SEDYIVSRVPFNYYTTSTALQKILEKPLEKK 2565
Query: 1860 RKNNYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
+NYGP K I FIDDMNMP ++YG L+R + D HWYD
Sbjct: 2566 AGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYD 2613
>AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein.
Length = 1659
Score = 939 bits (2325), Expect = 0.0
Identities = 532/1684 (31%), Positives = 888/1684 (52%), Gaps = 45/1684 (2%)
Query: 2124 TRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEESYIQ 2183
TRLAS I G FQ +T+SY+ + +D+K++ R +G K TF+FT+++IK+ES+++
Sbjct: 1 TRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLE 60
Query: 2184 NLDSLLNSGEVPNLYGLDEKQEI-LELVRLAAQGGNRNLDISPLQILAFFVGRCKAKLHI 2242
++++L+SGEV NL+ DE EI +L + + R L + + +F+ R + LHI
Sbjct: 61 YMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNE-NLHDYFMSRVRQNLHI 119
Query: 2243 VLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVK-SSA 2301
VLCFSP+G FR R +P+L++ CTIDW+ WP+DAL V+ H++ ++ ++
Sbjct: 120 VLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKE 179
Query: 2302 VIACK-QFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYT 2360
V+ C F +D+F F R T++T SYL I+ + + K E+R R
Sbjct: 180 VVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMN 239
Query: 2361 NGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQK 2420
GL++L +A+++VA + ++L A + +L V +K+ +++E+ ++ A+K A+V++ +
Sbjct: 240 TGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKD 299
Query: 2421 XXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMA 2480
+ K E L A P LE+A AAL T++P+DI V+++ PP+ + +M
Sbjct: 300 RAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMD 359
Query: 2481 AVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIR 2540
V + M W S +++ FL +L+ F KD I ++ +
Sbjct: 360 CVLLLFQRKVSAVKIDLEKSCTM-PSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFL- 417
Query: 2541 KEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMA 2600
Y D+ + GLC W AM + M
Sbjct: 418 SPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQ 477
Query: 2601 ILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVR 2660
L++ +A + +K+ L ++ + C K+ A LI GL GEK R
Sbjct: 478 DLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKER 537
Query: 2661 WTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFV 2720
WT ++ L GD+L++ ++Y P+ R +++ WR + +P +
Sbjct: 538 WTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLN 597
Query: 2721 FKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTND 2780
++L I W + GLP D SI N II + R+ LLIDPQ Q WIK E N+
Sbjct: 598 LSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNE 657
Query: 2781 LQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEF-IALGD 2839
LQ+ + +E L G+P LI+ V E+++ LD VL + +++ G F + +GD
Sbjct: 658 LQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLER-NFIKTGSTFKVKVGD 716
Query: 2840 NVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQE 2899
++ FRLY+TTKL NP Y PEI + ++I+F +T GLEDQ LG V+ E+ +L++
Sbjct: 717 KEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEK 776
Query: 2900 KREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEA 2959
+R L+ AN+ +K++ED++L L T+G ++EDES I VL ++K A ++ +K E
Sbjct: 777 ERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEI 836
Query: 2960 SLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKS 3019
S ETE I R YRP+A+ ++LY+ +TE+ V+ MYQ SL F+ L+ +S+ + KS
Sbjct: 837 SAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKS 896
Query: 3020 KDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITG 3079
KR+ + + TY +Y R L+++ K +F+ ++ K+ + ++ +E+ LI G
Sbjct: 897 PITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKG 956
Query: 3080 GIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNK 3137
G +++ KP +W+ D W + L+ L+ F D + W+ +D P+ +
Sbjct: 957 GASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEE 1016
Query: 3138 TLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNC 3197
LP +D+ L F++LL++R PD+ +++ MG KY D+ K++ +S+
Sbjct: 1017 PLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDP 1076
Query: 3198 LAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCL 3257
PLI +LS GSDP ++I +R+ R+ +S+GQGQ AR ++++ + GGW L
Sbjct: 1077 RTPLICLLSMGSDPTDSIIALGKRLKIETRY--VSMGQGQEVHARKLLQQTMANGGWALL 1134
Query: 3258 QNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGL 3317
QNCHL + ++ L I+ +L + +FRLW+T+ +FP ++LQ+ +K N+PP GL
Sbjct: 1135 QNCHLGLDFMDELMDIIIETELVHD--AFRLWMTTEVHKQFPITLLQMSIKFANDPPQGL 1192
Query: 3318 QHNLNRSY--ISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQY 3375
+ L R+Y +S+ L + + +LY ++F H+ VQER+KFG LGWNI Y
Sbjct: 1193 RAGLKRTYSGVSQDLLD-------VSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPY 1245
Query: 3376 GFNDSDFQISVMQLQMFLNQYE---EIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDN 3432
FN +DF +V +Q L+ + + + I+Y+ GE YGGRVTDD+D+RL+ T
Sbjct: 1246 EFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKV 1305
Query: 3433 YVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDY 3492
+ + + P++ F Q Y +P+ +YL++I+S+P PEVFGLH NA IT
Sbjct: 1306 WFSENMFG-PDFSFY---QGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQS 1361
Query: 3493 SISMELTSSLV-LVXXXXXXXXXXXXXXILVLMASEILSKLPPKF-DVEIAQKKYPVDYN 3550
++ ++ +++ + ++ +A ++L KLPP + E+ ++ +
Sbjct: 1362 KLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPF 1421
Query: 3551 ESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRK 3610
+ MN L QE++R ++L+ ++S+L +L+ A+ G I+MS L + M +IP W+K
Sbjct: 1422 QPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKK 1481
Query: 3611 FSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARA-KT 3669
S+ S L + + IER S W NG+P FW+ GFF Q FLT Q RA K
Sbjct: 1482 ASWVS-STLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKG 1540
Query: 3670 IPIDLLVFDFEIRN--VDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMP 3727
+D +V E+ D + PP GV+V GL+++G W++ + E PKVL + MP
Sbjct: 1541 WALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMP 1600
Query: 3728 VIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRS 3787
VI +Y + N + Y CP+YK R + N++ A L + + HW+ R
Sbjct: 1601 VIRIYAE-NNTLRDPRFYSCPIYKKPVRTDL--------NYIAAVDLRTAQTPEHWVLRG 1651
Query: 3788 VALL 3791
VALL
Sbjct: 1652 VALL 1655
>AK023766-1|BAB14671.1| 892|Homo sapiens protein ( Homo sapiens cDNA
FLJ13704 fis, clone PLACE2000274, weakly similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 892
Score = 834 bits (2063), Expect = 0.0
Identities = 404/883 (45%), Positives = 578/883 (65%), Gaps = 7/883 (0%)
Query: 2775 MEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEF 2834
MEK N L V K D ++++ +E + +GKP L++ V E+++ L+PVLLK TY Q G
Sbjct: 1 MEKDNGLDVFKLGDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGSTV 60
Query: 2835 IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKER 2894
+ LGD VI YH +FR+Y+TTKL NPHY PEI K+TLINF L+ GLEDQ LG VVA+ER
Sbjct: 61 LKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEER 120
Query: 2895 PDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIM 2954
PDL+E + +LI+ A R LK +ED IL L ++G+ ++D I+VL++SK A +I
Sbjct: 121 PDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQ 180
Query: 2955 KKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIE 3014
K + +TE I+ R+ Y P+A + +L++CV++L NVDPMYQYSL WF+N+++ I
Sbjct: 181 AKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIV 240
Query: 3015 NANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYK 3074
N+ ++ +L+KR+ + TY+LYSNVCRSLF+K KLMF+F++C ++M++ K+N E++
Sbjct: 241 NSVRADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWR 300
Query: 3075 FLITGG-IAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIE 3133
+L++GG I++ P +WL D+AW +I L++L F +F DFVK + +++ ++D +E
Sbjct: 301 YLLSGGSISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLE 359
Query: 3134 PQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFG 3193
P + LPG WD+ L QFQKLLV+R LR DK+T A+ F+ + ++ P ++S F
Sbjct: 360 PHRELLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFK 419
Query: 3194 DSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGG 3253
DSN PLIF+LSPG+DP L K+ E M FS + ++ISLGQGQGP A AM+ + G
Sbjct: 420 DSNSTTPLIFVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGK 479
Query: 3254 WVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEP 3313
WV QNCHLA SW+P LE+++E + FRLWLTS PS+KFP S+LQ G KMT EP
Sbjct: 480 WVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEP 539
Query: 3314 PTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNI 3373
P G++ NL +SY S L E +F C K F LL + FH ER+KFGPLG+NI
Sbjct: 540 PRGVRANLLKSYSS--LGE-DFLNSC-HKVMEFKSLLLSLCLFHGNALERRKFGPLGFNI 595
Query: 3374 QYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNY 3433
Y F D D +I + QL+MFL++Y++I Y +KY GE NYGGRVTDDWDRR I+ IL+++
Sbjct: 596 PYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDF 655
Query: 3434 VNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYS 3493
N V++ P + + G + +P + YL +I+S+P+N PE+FGLH NA IT +
Sbjct: 656 YNPDVLS-PEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQN 714
Query: 3494 ISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESM 3553
+ L +++ + I+ + IL K+P +++ KYPV Y ESM
Sbjct: 715 ETFALLGTIIQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESM 774
Query: 3554 NTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSY 3613
NTVL+QE+ R+N+LL I +LQDL KA+KGL+VMS L+L + ++ +PE W +Y
Sbjct: 775 NTVLVQEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAY 834
Query: 3614 PSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAF 3656
PSLKPL S+V D ++RL L+ W Q+G P FW+ GFFF QAF
Sbjct: 835 PSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAF 877
>AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein.
Length = 2992
Score = 725 bits (1793), Expect = 0.0
Identities = 433/1327 (32%), Positives = 684/1327 (51%), Gaps = 42/1327 (3%)
Query: 1941 PTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYDRLVDDQDRAW 2000
PT K HYIFNLRDF+ + QG E + I++++HE RV+ D++V+++D
Sbjct: 1250 PTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKD--- 1306
Query: 2001 FFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSAEGERRYEEIP 2060
F + K + +K TF+ +D + N+ Y + GE +Y +
Sbjct: 1307 -FDLFDKIQTEVLKKTFDDI----EDPVEQTQSPNL-------YCHFANGIGEPKYMPVQ 1354
Query: 2061 SKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGR 2120
S E+ V L +N ++ M +VLF+ A+ H+ I RIL P GNALLVGVGGSG+
Sbjct: 1355 SWELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 1413
Query: 2121 QSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEES 2180
QSLTRLA+ I VFQ + K Y ++D+ D+ + ++G N +T FL T++Q+ +E
Sbjct: 1414 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 1473
Query: 2181 YIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDISPLQILAFFVGRCKAKL 2240
++ ++ LL SGE+P+LY DE + I+ VR + ++ L + FF+ R + +L
Sbjct: 1474 FLVLINDLLASGEIPDLYSDDEVENIISNVRNEVK--SQGLVDNRENCWKFFIDRIRRQL 1531
Query: 2241 HIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSS 2300
+ LCFSP+G+ R R R +P++VNC I W+ WP+ ALE V+ ++ +P
Sbjct: 1532 KVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQ 1591
Query: 2301 AVIACKQF-HVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRY 2359
++ F H S + ++ R Y T S+L+ I+ + +L +R ++EL+ R
Sbjct: 1592 SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERL 1651
Query: 2360 TNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQ 2419
NGL +L + V ++ L A + +L E + K++Q + VET + A E++
Sbjct: 1652 ENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEE 1711
Query: 2420 KXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVM 2479
+ + +KDCE DLA A P L A AALNTL ++T +KS +PP V V
Sbjct: 1712 QKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVS 1771
Query: 2480 AAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDM-GFLDSLKNFDKDNIPVATMQK 2538
AAV V W +K + + GFLDSL NF+K+NI ++
Sbjct: 1772 AAVMVLMAPRGRVPKDRS---------WKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 1822
Query: 2539 IRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQT 2598
IR YL + +F P VA S AA GLC W+I + +
Sbjct: 1823 IRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA 1881
Query: 2599 MAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEK 2658
L KA + K + E ++ + A +L+GGL E
Sbjct: 1882 QEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASEN 1941
Query: 2659 VRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WRDLV--IKLNMPH 2715
VRW A +N + L GDIL+ I+YL +T R ++D+ WR + +K +P
Sbjct: 1942 VRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPV 2001
Query: 2716 SEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTM 2775
+ +L D + W GLP D S++NA I N RW L++DPQ Q KWIK
Sbjct: 2002 TPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN- 2060
Query: 2776 EKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFI 2835
+ DL+V + Y+++IE LE G LI+ + E ++ L P+L + +G FI
Sbjct: 2061 KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFI 2118
Query: 2836 ALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERP 2895
+GD EY+P FRL + TKL NPHY PE+ + TLINF +T+DGLEDQ L VV+ ERP
Sbjct: 2119 KIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERP 2178
Query: 2896 DLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMK 2955
DL++ + L Q + LK +ED +L L G+ L + +E L+ +K A ++ K
Sbjct: 2179 DLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEK 2238
Query: 2956 KQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIEN 3015
K + + TE I + R YRP A+ +++LY+ + +L + PMYQ+SL F ++ ++E
Sbjct: 2239 KVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVER 2298
Query: 3016 ANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKF 3075
A + L +R+ L D+ T+++Y R LF+ DKL + + +++L ++N E F
Sbjct: 2299 AAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDF 2358
Query: 3076 LITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQ 3135
L+ V+ PVE+L +AW + L+ ++ F D + W++ + P+
Sbjct: 2359 LLRS--PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPE 2416
Query: 3136 NKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDS 3195
+ LP W + T Q+L ++R +RPD++T A+ F+E+++G KY D + SF +S
Sbjct: 2417 KEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEES 2475
Query: 3196 NCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQGQGPIARAMIEKAQSEG 3252
P+ FILSPG DP+ + ++G+ + F+++SLGQGQ +A A ++ A +G
Sbjct: 2476 GPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKG 2535
Query: 3253 GWVCLQN 3259
WV LQN
Sbjct: 2536 HWVILQN 2542
Score = 333 bits (819), Expect = 6e-90
Identities = 194/534 (36%), Positives = 288/534 (53%), Gaps = 36/534 (6%)
Query: 842 VLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFS-SK 900
VL+D+ V+ + S +V F +V W +K+ V+A I W +VQ W +L IF+ S+
Sbjct: 53 VLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSE 112
Query: 901 DIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGV 960
DI AQ+P++ F ++ ++ K P+V++ G+ E L +
Sbjct: 113 DIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKAL 172
Query: 961 NNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEFN---I 1017
YL+ KRL FPRF+FLS+ ++L+ILS P +VQ HL K F+ + ++ F + +
Sbjct: 173 AEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPT 232
Query: 1018 SAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGRVEW 1077
+ M ++ E++ G VE WL V M V+ E Y R +W
Sbjct: 233 KTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQW 292
Query: 1078 VLSWEGMVVLAISQIYWAVDVHES---LNTHKLSELQAFHSELTKQLNETVAVIRRTDLT 1134
+ V L +QI+W +V + L S ++ ++ + QL +T+ + L+
Sbjct: 293 LFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL-KTLITMLIGQLS 351
Query: 1135 KLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAV 1192
K + + IDVHA+DV++ +I +KV F WL+QLR+ W++E + I +A
Sbjct: 352 KGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQ 411
Query: 1193 VHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAV 1252
Y+YEYLGN+ RLVITPLTDRCY TL + +L ++GAP GPAGTGKTETTKDL +AL +
Sbjct: 412 FLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGI 471
Query: 1253 QCVVFNCSDGLDYKAMGKFFKGLASCGAW--------------------------AVRQH 1286
VFNCS+ +DYK+ G +KGLA GAW A+R
Sbjct: 472 LVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDK 531
Query: 1287 LETFDFEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMI 1340
+ F F G + LNP+ + ITMNPGYAGR+ELP+NLK LFR AM+VPD+ +I
Sbjct: 532 KQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELI 585
Score = 303 bits (743), Expect = 1e-80
Identities = 180/568 (31%), Positives = 292/568 (51%), Gaps = 25/568 (4%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
E LS Q+HYD+G+RA+K+VL AG+LKR P+ E +L+RS+ D N+PK ++ D+P+F
Sbjct: 614 ELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFM 673
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
G+I DLFP + +P+ NF + LQ + F++KV+Q E++ VRH +VG
Sbjct: 674 GLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVG 733
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
+GKS L+ L + ++ R + LNPKAVT +L+G +P + EW DG
Sbjct: 734 GAGTGKSQVLRSLHKTYQIMKRRP-------VWTDLNPKAVTNDELFGIINPATGEWKDG 786
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
+ +++ RE A+ KWI+ DG +D +WIE++NTV+DDNK L L S E + ++ M +
Sbjct: 787 LFSSIMRELANTTHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKL 846
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEEYIYDMCDWL 1640
+FE+ L A+PATVSR G++Y+ LG+ P SW+ ++ + + D
Sbjct: 847 LFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKRE---IQTERANLTILFDKY 903
Query: 1641 FDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNA-IEGEEDTKYTRTWFLASLMTA 1699
+ +R +++ E ++V L+E L+ I + + +F + A
Sbjct: 904 LPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYF----VFA 959
Query: 1700 IVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDHFYMYKGKGC 1759
+W GG + D + D E+ K E V P++G + D++ + K
Sbjct: 960 AIWAFGGAMVQD---QLVDYRAEFSKW-----WLTEFKTVKFPSQGTIFDYYIDPETKK- 1010
Query: 1760 WKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGPTGTGKSFYV 1819
++ W V + ++ L ++ T ET + Y + +P++L+G GTGKS V
Sbjct: 1011 FEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLV 1070
Query: 1820 QNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYGPTRGKHAIIFIDDM 1879
+ +LD E Y + ++ Q ++ L K+ NYGP K I FIDDM
Sbjct: 1071 -GAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDM 1129
Query: 1880 NMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
NMP + YG ++R + D HWYD
Sbjct: 1130 NMPEVDAYGTVQPHTIIRQHLDYGHWYD 1157
Score = 238 bits (583), Expect = 2e-61
Identities = 144/459 (31%), Positives = 229/459 (49%), Gaps = 21/459 (4%)
Query: 3342 KDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQY 3401
++ F +L+ + +FHAVV ER+KFGP GWN Y FN D ISV L FL ++ Y
Sbjct: 2549 RETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPY 2608
Query: 3402 VAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEY 3461
++YL GE YGG +TDDWDRRL T L ++ ++ L + LP +Y
Sbjct: 2609 DDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGE----LSLAPGFPLPGNMDY 2664
Query: 3462 QDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXXXX 3518
Y ++I++ P ++GLH NA I S +L +++ +
Sbjct: 2665 NGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATRE 2724
Query: 3519 XILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDL 3578
+ + EIL ++ +F++ K V+ V QE R N L EI+ SL++L
Sbjct: 2725 EKVKALLEEILERVTDEFNIPELMAK--VEERTPYIVVAFQECGRMNILTREIQRSLREL 2782
Query: 3579 QKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQ 3638
+ +KG + M+ ++ NA+ +PE+W + +YPS L ++ D + R+ LE W
Sbjct: 2783 ELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTG 2842
Query: 3639 N-GKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIRNVDYETTPPKWGV 3695
+ P T WL GFF Q+FLT +Q+ AR P+D + D +N + +PP+ G
Sbjct: 2843 DFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGA 2902
Query: 3696 FVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLER 3755
++ GLFM+G W+ + I E K L MPV+++ ++ + + Y CP+YKT +R
Sbjct: 2903 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 2962
Query: 3756 KGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
+V F L + + + W+ VALLLQ+
Sbjct: 2963 ---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 2992
>AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 690 bits (1706), Expect = 0.0
Identities = 411/1329 (30%), Positives = 672/1329 (50%), Gaps = 17/1329 (1%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSE 3251
+I+ + +
Sbjct: 4155 KLIQMSMQQ 4163
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 690 bits (1706), Expect = 0.0
Identities = 411/1329 (30%), Positives = 672/1329 (50%), Gaps = 17/1329 (1%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSE 3251
+I+ + +
Sbjct: 4155 KLIQMSMQQ 4163
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 690 bits (1706), Expect = 0.0
Identities = 411/1329 (30%), Positives = 672/1329 (50%), Gaps = 17/1329 (1%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSE 3251
+I+ + +
Sbjct: 4155 KLIQMSMQQ 4163
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 690 bits (1706), Expect = 0.0
Identities = 411/1329 (30%), Positives = 672/1329 (50%), Gaps = 17/1329 (1%)
Query: 1931 IYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEIMRVFYD 1990
++ + + PTP+K HYIFNLRD SR+ QG ++ E + T + ++ HE RV D
Sbjct: 2844 LWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIAD 2903
Query: 1991 RLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCYLDTDSA 2050
R + +D WF L TR ++ A E V+ G +
Sbjct: 2904 RFITPEDEQWFNAHL---TRAVEENIGSDAASCILPEPYFVDFLREMPEPTGDEPEDSVF 2960
Query: 2051 EGERRYEEIPSKEVFLNIAVSMLSEYNSMHKA-KMTIVLFDYALEHLSKICRILSMPSGN 2109
E + YE +PS + ++N + + + +V F A+ HL KI RI+ GN
Sbjct: 2961 EVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGN 3020
Query: 2110 ALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLNKDTTF 2169
ALLVGVGGSG+QSL+RLAS I G Q+FQ +T+SY+V + DD+K + + +G K TF
Sbjct: 3021 ALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITF 3080
Query: 2170 LFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILE-LVRLAAQGGNRNLDISPLQI 2228
+FT+S+IK+E++++ L++LL+SGE+ NL+ DE EI + L+ + + R+ +
Sbjct: 3081 IFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFD-NL 3139
Query: 2229 LAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM 2288
+F+ R + LH+VLCFSP+G FR R +P L++ CT+DW+ WP +AL VA +++
Sbjct: 3140 YEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFL 3199
Query: 2289 VKVNV--PDPVKSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTN 2346
N+ +K V FH +F + R ++T SYL I + +
Sbjct: 3200 SDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYA 3259
Query: 2347 RKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETA 2406
K + + R GLD+L +A+++VA + +DL + +L V + K+ +++ E+ V
Sbjct: 3260 EKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQ 3319
Query: 2407 IADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVK 2466
+ K +V+E + K E+ L A P LE+A AALNT+KP DI V+
Sbjct: 3320 ASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVR 3379
Query: 2467 SMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNF 2526
+ PP+ + +M V + WG S +++ GFL SL+ F
Sbjct: 3380 KLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCK-PSWGESLKLMSATGFLWSLQQF 3438
Query: 2527 DKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXX 2586
KD I T++ ++ Y + D+ K GL W +AM ++
Sbjct: 3439 PKDTINEETVELLQP-YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKA 3497
Query: 2587 XXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFR 2646
A L + +A++ +K L ++ C K+
Sbjct: 3498 NLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQA 3557
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEII-DKWR 2705
A LI GL GEK+RWT ++ + + L GDIL+ G ++YL P+ R ++ D+W
Sbjct: 3558 ASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWE 3617
Query: 2706 DLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQ 2765
+ +P +E +L I W + GLP D SI N II + R+ LLIDPQ
Sbjct: 3618 MELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQ 3677
Query: 2766 GQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKL 2825
Q WIK+ EK NDLQV + +E L G+P LI+ + E+++ LD VL K
Sbjct: 3678 TQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEK- 3736
Query: 2826 TYLQGGKEF-IALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQ 2884
+++ G F + +GD + F+LY+TTKL NP + PEI K ++I+F +T GLE+Q
Sbjct: 3737 NFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQ 3796
Query: 2885 SLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLD 2944
L V+ E+ +L+ +R KL+ N+ +K++ED++L L TKG +++DES I VL
Sbjct: 3797 LLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLR 3856
Query: 2945 SSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTW 3004
++K A ++ +K + ETE I + +RP A+ ++LY+ +TE+ V+ MYQ SL
Sbjct: 3857 TTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQ 3916
Query: 3005 FINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLS 3064
F+ L+ S+ + KS +KR+ + + TY +++ R L++ K +F +M K+ L
Sbjct: 3917 FLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQ 3976
Query: 3065 TEKMNVDEYKFLITGGIAVENHL--KKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTI 3122
+ E++ LI GG A++ KP W+ D W + L+ L F + +
Sbjct: 3977 RGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNE 4036
Query: 3123 IKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT 3182
W+ +D P+ + +P G+++ L KLL++R PD+ +++ + KYT
Sbjct: 4037 KGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTE 4096
Query: 3183 PPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIAR 3242
P ++ K++ +S+ PLI LS GSDP + +++ R +IS+GQGQ AR
Sbjct: 4097 PVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKLECR--TISMGQGQEVHAR 4154
Query: 3243 AMIEKAQSE 3251
+I+ + +
Sbjct: 4155 KLIQMSMQQ 4163
Score = 578 bits (1428), Expect = e-163
Identities = 389/1264 (30%), Positives = 632/1264 (50%), Gaps = 125/1264 (9%)
Query: 757 IKDWRPNVQMAHIMCNPALVQRHWDEMSTIAG--FDLTPTAGTSLRKIINFNLWGDLDQY 814
I D+ + + +M N A+ QRHWD +S + G FD+ + LR I+ L D
Sbjct: 1544 IDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS-FCLRNIMEAPLLKHKDDI 1602
Query: 815 EIISVAATKELALITNLNKMMAEW-------------------------IQSVLDDHIVK 849
E I ++A KE + L +++ W I ++++D ++
Sbjct: 1603 EDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMV 1662
Query: 850 TVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLLPIFSSKDIVAQMPEE 909
+ + + PF+ ++ W K+ + I+EW VQ+ W+YL +F DI Q+P+E
Sbjct: 1663 LGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQE 1722
Query: 910 GVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGIL-EAFRAATAFLEKINDGVNNYLEKKR 968
F ++ + + M ++P+V+ G + + LE + YLEKKR
Sbjct: 1723 AKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKR 1782
Query: 969 LYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGEF--NISAMISMEGE 1026
L FPRFFF+S+ +LEIL + + +QPHL + IN + F + I A+IS EGE
Sbjct: 1783 LLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHAKDYDRIMAVISREGE 1842
Query: 1027 QVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMG--RVEWVLSWEGM 1084
++ LD + A+G VE WL+ + + + ++ + ++Y + G + ++ +
Sbjct: 1843 KI-VLD--NSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQ 1899
Query: 1085 VVLAISQIYWAVDVHESLNTHKLSE--LQAFHSELTKQLNETVAVIRRTDLTKLSSITVK 1142
V L Q+ W D E+L K +Q + + LN ++ DL+K + +
Sbjct: 1900 VGLLGIQMLWTHDSEEALRNAKDDRKIMQVTNQKFLDILNTLISQTTH-DLSKFDRVKFE 1958
Query: 1143 ALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYL 1200
LI I VH +D+ DL+K + TDF+WL Q R+Y++E+ + V I + Y E+L
Sbjct: 1959 TLITIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFL 2018
Query: 1201 GNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCS 1260
G +DRLVITPLTDRCY TL A +++ GAP GPAGTGKTETTKD+ + L VVFNCS
Sbjct: 2019 GCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCS 2078
Query: 1261 DGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLETFDF-E 1293
D +D++ +G+ FKGLA G+W A ++ + F F +
Sbjct: 2079 DQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD 2138
Query: 1294 GTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLS--------- 1344
G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD +I ++
Sbjct: 2139 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLEN 2198
Query: 1345 ---SQNHY----------------DYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITD 1385
+Q Y D+G+R + +VL G+ KR+ P +SE +++R + D
Sbjct: 2199 VILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRD 2258
Query: 1386 VNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQ 1445
+NL K + D PLF +I+DLFPG+ L Y NA + L + +K++Q
Sbjct: 2259 MNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQ 2318
Query: 1446 TYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQ 1505
YE +VRHG M +G SGK+ + +L +A + E +P +NPKA+T Q
Sbjct: 2319 LYETSLVRHGLMTLGPSGSGKTTVITILMKAQT---ECGRPH----REMRMNPKAITAPQ 2371
Query: 1506 LYGAFDPISYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLC 1565
++G D + +WTDGI +T++R+ +++ DGPVDA+WIEN+N+VLDDNK L
Sbjct: 2372 MFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLT 2431
Query: 1566 LTSGEVMAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIW 1625
L +G+ + M+ ++FEV ++ ASPATVSR GM+Y+ S++L + P ++WL
Sbjct: 2432 LANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRT--- 2488
Query: 1626 LEENEEYIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVEMLMDNAIEGEED- 1684
+ + + +F+ Y++ + E N ++ +L L+E L+ + EG
Sbjct: 2489 -AQEAAVFLTLYEKVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSC 2547
Query: 1685 TKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAE 1744
++ F+ LM W LG +L +SREK + ++++ SK++ ++
Sbjct: 2548 VEHLHKLFVFGLM----WSLGALLELESREKLEAFLRQH-------ESKLDLPEIP-KGS 2595
Query: 1745 GMLIDHFYMYKGKGCWKTWPDAVKAVQV-KEQINLLQTV-IPTLETEKFMYLLNLHSKYL 1802
+ FY+ G W+ W ++ + I ++ +P ++ + +L++ +K
Sbjct: 2596 NQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQH 2654
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
K +LL G GT K+ V+ +L D E + Q + S + KR +
Sbjct: 2655 KAVLLTGEQGTAKTVMVKAYL-KKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGS 2713
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDL-KTTDKLFIYDTIF 1921
YGP G+ +FIDD+NMP +G Q E++R + + Y L K D I D
Sbjct: 2714 TYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQL 2773
Query: 1922 YGAI 1925
A+
Sbjct: 2774 IAAM 2777
>AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens cDNA
FLJ46675 fis, clone TRACH3009701, weakly similar to Homo
sapiens dynein, axonemal, heavy polypeptide 9 (DNAH9). ).
Length = 901
Score = 650 bits (1607), Expect = 0.0
Identities = 332/902 (36%), Positives = 508/902 (56%), Gaps = 23/902 (2%)
Query: 2431 ELKKDCEADLALALPILEDAIA---ALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXX 2487
E +K CE L + + +A AL +L DI +KS PP V++VM AV +
Sbjct: 14 EFQKQCEEYLVIIVQQKREADEQQKALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRG 73
Query: 2488 XXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNK 2547
W +KR LG+ F+ SL NFDKDNI ++KI Y +
Sbjct: 74 NEPT---------------WAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGA-YCAQP 117
Query: 2548 DFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKA 2607
DF+P I+ + S AA+ LC W+ AM++Y + A L E +
Sbjct: 118 DFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQE 177
Query: 2608 MVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAEN 2667
+ +K+ L + + KL RA L+ GL GEK RW +
Sbjct: 178 KLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQG 237
Query: 2668 LQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WRDLVIKLNMPHSEQFVFKDVLG 2726
L+ L GD L++ ++Y+ P+ R EI+++ W + +L +P S F + L
Sbjct: 238 LEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLC 297
Query: 2727 TDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKF 2786
K+++W I GLP D FS +N II RW+L+IDPQ QA KWIK ME L+++
Sbjct: 298 NPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDL 357
Query: 2787 TDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHP 2846
+Y++++E + +G P L+ V E ++ L+P+L K GG+ + +GD +EY+
Sbjct: 358 QMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNT 417
Query: 2847 NFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIV 2906
NFR Y+TTKL NPHY PE K T++NFA+ + GLE Q LGIVV KERP+L+E+++ L++
Sbjct: 418 NFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVI 477
Query: 2907 QGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETI 2966
AA + LK++ED+ILR L E G +L+D + L +SK A ++ ++ E S TE
Sbjct: 478 NIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEIN 537
Query: 2967 IEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRL 3026
+ R YRP A +++L++ + ++ +DPMYQ+SL +I+L+I+SI+ +++S LE R+
Sbjct: 538 TDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRI 597
Query: 3027 KFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAV--E 3084
+L D TY +Y CR+LF++ KL+FSF MC+K++ ++ K+N+DEY F + GG+ + E
Sbjct: 598 DYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDRE 657
Query: 3085 NHLKKPV-EWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGW 3143
+ P WL D WD I L+ L F + F + W Y + P+ LPG W
Sbjct: 658 GQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEW 717
Query: 3144 DERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIF 3203
+ + Q++L+VR LR D++ V+ F+ +G ++ PP ++ DS +PL+F
Sbjct: 718 ENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVF 777
Query: 3204 ILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLA 3263
ILSPG DP AL++ E MG + RF+++SLGQGQ PIA ++ + ++G WV L NCHL+
Sbjct: 778 ILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLS 837
Query: 3264 VSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNR 3323
+SW+P L+K+VE + + SFRLWL+S P FP S+LQV +KMT EPP GL+ N+ R
Sbjct: 838 LSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTR 897
Query: 3324 SY 3325
Y
Sbjct: 898 LY 899
>AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 1179
Score = 619 bits (1530), Expect = e-176
Identities = 372/1165 (31%), Positives = 617/1165 (52%), Gaps = 43/1165 (3%)
Query: 2647 AEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WR 2705
A +L+GGL E +RW + EN ++ L GD+L+ ++Y+ +T R E+++K W
Sbjct: 41 ANRLVGGLASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWI 100
Query: 2706 DLV--IKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLID 2763
+ +K+ +P + +L D + W GLP D S +NA I N+ RW L++D
Sbjct: 101 PYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVD 160
Query: 2764 PQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLL 2823
Q Q KWIK ++ +L+ ++ +Y+ VIE G LI+ + E V+ LDP+L
Sbjct: 161 AQLQGIKWIKNKYRS-ELKAIRLGQKSYLDVIEQATSEGDTLLIENIGETVDPALDPLLG 219
Query: 2824 KLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLED 2883
+ T +G ++I +GD + P T ++ P V LINF +T+DGLED
Sbjct: 220 RNTIKKG--KYIKIGDKEVGVPPQVPPDPTHQVLQPTLQARDAGSVHLINFLVTRDGLED 277
Query: 2884 QSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVL 2943
Q L VVAKERPDL++ + L + LK++ED +L L G+ L D + +E L
Sbjct: 278 QLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTTLVENL 337
Query: 2944 DSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLT 3003
+++K+ A +I +K + TE I + R YRP A +++LY+ + +L ++P+YQ+SL
Sbjct: 338 ETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLK 397
Query: 3004 WFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMML 3063
F ++ +I+ + ++++R+ L D TY++Y R LF++DKL+F + +++
Sbjct: 398 AFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLS 457
Query: 3064 STEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTII 3123
+++N E FL+ + + PV++L + W I L+++ F+ D +
Sbjct: 458 MKKELNPVELDFLLR--FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAK 515
Query: 3124 KWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTP 3183
+W+++ + P+ + P W + T QKL +VR LRPD++T A+ F+E++MG K+
Sbjct: 516 RWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEG 574
Query: 3184 PPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQGQGPI 3240
+ SKS+ +S+ + FILSPG DP+ + +++GF + + +++SLGQGQ +
Sbjct: 575 RSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVV 634
Query: 3241 ARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDK--- 3297
A ++ A +G WV LQN HL WL L+K +E + T +R+++ + P+
Sbjct: 635 AENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYS-TGRHEDYRVFIRAEPAPSPET 693
Query: 3298 --FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISF 3355
PQ +L+ +K+TNEPPTG+ NL Y + L + E C K+ F +L+ + +
Sbjct: 694 HIIPQGILENAIKITNEPPTGMYANL---YKALDLFTQDTLEMCT-KEMEFKCMLFALCY 749
Query: 3356 FHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGG 3415
FHAVV ER+KFG GWN Y FN+ D IS+ L +L ++ + ++YL GE YGG
Sbjct: 750 FHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGG 809
Query: 3416 RVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINP 3475
+TDDWDRRL T L Y+ + ++ + + L L + +P +Y+ Y ++I+
Sbjct: 810 HITDDWDRRLCRTYLAEYIRTEML-EGDVL---LAPGFQIPPNLDYKGYHEYIDENLPPE 865
Query: 3476 PPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXXXXXILVLMASEILSKL 3532
P ++GLH NA I S +L +++ + + + +IL K+
Sbjct: 866 SPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKI 925
Query: 3533 PPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPAL 3592
P F+ +A+ V QE ER N L NE++ SL++L +KG + ++ +
Sbjct: 926 PETFN--MAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDV 983
Query: 3593 DLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQN-GKPPTFWLPGFF 3651
+ S A+ +P+ W +YPS+ L ++ AD + R+ LE W + P T WL GFF
Sbjct: 984 EDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFF 1043
Query: 3652 FTQAFLTGSVQNYARAKTIPIDLLVFDFEI--RNVDYETTPPKWGVFVQGLFMDGGRWNR 3709
Q+ LT +Q+ AR P+D + E+ +N + T PP+ G +V GLFM+G RW+
Sbjct: 1044 NPQSLLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDT 1103
Query: 3710 ETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFV 3769
+T IAE K L MPVI++ Y+CP+YKT R +V
Sbjct: 1104 QTGVIAEARLKELTPAMPVIFIKAIPVARMETKNIYECPVYKTRIR---------GPTYV 1154
Query: 3770 LAFYLPSDKPSAHWIKRSVALLLQL 3794
F L + + +A WI +VALLLQ+
Sbjct: 1155 WTFNLKTKEKAAKWILAAVALLLQV 1179
>AC002394-2|AAC05809.1| 573|Homo sapiens Gene product with similarity
to dynein beta subunit protein.
Length = 573
Score = 609 bits (1503), Expect = e-173
Identities = 290/572 (50%), Positives = 384/572 (67%), Gaps = 5/572 (0%)
Query: 3227 RFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLT-NTDLS 3285
R +ISLGQGQGPIA MI A +G WV LQNCHLA SW+P LEKI E + +T+
Sbjct: 5 RTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNAR 64
Query: 3286 FRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKT 3345
FRLWLTSYPS+KFP S+LQ G+KMTNEPP GL+ NL RSY+++P+ +P F++ C K
Sbjct: 65 FRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSC-AKAVM 123
Query: 3346 FSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIK 3405
+ K+L+G+ FFHAVVQER+ FGPLGWNI Y FN+SD +IS+ Q+QMFLN Y+E+ + A+
Sbjct: 124 WQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALT 183
Query: 3406 YLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYL 3465
YLTGECNYGGRVTDD DRRL++++L + + D Y G Y +P YQ Y+
Sbjct: 184 YLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEED--YYSLAPGDTYYIPPHGSYQSYI 241
Query: 3466 KHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMA 3525
++ ++PI PEVFGLH NA IT+D + +L ++L ++ +A
Sbjct: 242 DYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQSGGSGKSPQEVVEELA 301
Query: 3526 SEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGL 3585
+ILSKLP FD+E K YPV Y ESMNTVL QE+ RFN+L ++ SL +L +A+KG
Sbjct: 302 QDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQ 361
Query: 3586 IVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTF 3645
++MS L+ N+ML+GK+P W SYPSLKPL YVAD + RL+ ++W G P F
Sbjct: 362 VLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDKGPPVVF 421
Query: 3646 WLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVD-YETTPPKWGVFVQGLFMDG 3704
W+ GF+FTQ+FLTG QNYAR TIPID + F+FE+ + P+ G +++GLF++G
Sbjct: 422 WISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETVMENNPEDGAYIKGLFLEG 481
Query: 3705 GRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGH 3764
RW+R+T I E LPK+L D +P+IWL P F Y CP+YKT R+G L+TTGH
Sbjct: 482 ARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGH 541
Query: 3765 SSNFVLAFYLPSDKPSAHWIKRSVALLLQLDN 3796
S+N+VL+ LP+D P HWI R VA L QLDN
Sbjct: 542 STNYVLSIELPTDMPQKHWINRGVASLCQLDN 573
>BC029567-1|AAH29567.1| 507|Homo sapiens DNAH7 protein protein.
Length = 507
Score = 582 bits (1437), Expect = e-165
Identities = 272/509 (53%), Positives = 358/509 (70%), Gaps = 2/509 (0%)
Query: 3288 LWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFS 3347
+WLTSYPS FP SVLQ GVKMTNE P GL+ N+ RSY+ +P+ + EF+ C K + F
Sbjct: 1 MWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDLEFFGSCK-KPEEFK 59
Query: 3348 KLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYL 3407
KLLYG+ FFHA+VQER+KFGPLGWNI Y FN++D +ISV QL MFLNQYEE+ Y A++Y+
Sbjct: 60 KLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYM 119
Query: 3408 TGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKH 3467
TGECNYGGRVTDDWDRR + +IL+ + N +V + +Y F G Y +P +++ Y+++
Sbjct: 120 TGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGI-YFVPPSGDHKSYIEY 178
Query: 3468 IESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASE 3527
+++P+ P PE+FG++ NA IT+D S + L +++L ++ +AS+
Sbjct: 179 TKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASD 238
Query: 3528 ILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIV 3587
IL KLP FD+E A ++YP Y +SMNTVL+QEM RFNKLL I+ S ++QKA+KGL V
Sbjct: 239 ILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLAV 298
Query: 3588 MSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPPTFWL 3647
MS L+ +++L KIPE W SYPSLKPL SYV DF+ RL L+ WY+ G PP FWL
Sbjct: 299 MSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWL 358
Query: 3648 PGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRW 3707
GFFFTQAFLTG+ QNYAR TIPIDLL FD+E+ PP+ GVF+ GLF+DG W
Sbjct: 359 SGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLDGASW 418
Query: 3708 NRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSN 3767
NR+ +AE PK+L D +PV+WL P + + + Y PLYKT ER+GVL+TTGHS+N
Sbjct: 419 NRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGHSTN 478
Query: 3768 FVLAFYLPSDKPSAHWIKRSVALLLQLDN 3796
FV+A LPSD+P HWI R VALL QL++
Sbjct: 479 FVIAMTLPSDQPKEHWIGRGVALLCQLNS 507
>AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein.
Length = 1685
Score = 576 bits (1423), Expect = e-163
Identities = 435/1704 (25%), Positives = 784/1704 (46%), Gaps = 75/1704 (4%)
Query: 2084 MTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKS 2143
+ I+LF LE++S+I R+LS P G+ LL G G GR+++T L S + G +F P+I++
Sbjct: 3 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 62
Query: 2144 YSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEK 2203
Y +K + +D+K VL+ +G + L + Q ++++ ++SLL+SGEVP LY L+E
Sbjct: 63 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 122
Query: 2204 QEIL-ELVRLAAQGGNRNLDISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPS 2262
+ +L L A+Q G P + +F R + LHIVL S+F P+
Sbjct: 123 EPLLLPLKDQASQDGF----FGP--VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPA 176
Query: 2263 LVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSSAVIACKQFH-VDARIVSIDFFN 2321
L C + W + W +++ + + + K+ + VD +
Sbjct: 177 LHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLI 236
Query: 2322 HFGRETY-ITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDL 2380
H + Y T + Y+ + ++ +++ K++EL + G+ +L +A V + R
Sbjct: 237 HESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKA 296
Query: 2381 NALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADL 2440
L +++ +Q I V A + ++ + E K + +L
Sbjct: 297 GEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDEL 356
Query: 2441 ALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXX 2500
P++ +A A+ +KP ++ ++S++ PP ++ ++ V
Sbjct: 357 KEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVL---------------RL 401
Query: 2501 XXMFDF-WGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNK-DFKPHIVAKAS 2558
+FD W K L G + + FD NI + + + NK F P +AS
Sbjct: 402 MGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRAS 461
Query: 2559 AAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXX 2618
AA L W+ A Y +T + + ++
Sbjct: 462 TAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSE 521
Query: 2619 XXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGD 2678
+ LE EV + + AE LI L E RW + L
Sbjct: 522 LKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKR 581
Query: 2679 ILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAG 2738
++ I YL+ +R +++W E+F + L T+ + W G
Sbjct: 582 AQLAAAFITYLSAAPESLRKTCLEEWT------KSAGLEKFDLRRFLCTESEQLIWKSEG 635
Query: 2739 LPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETC 2798
LP D SI+NA++ S LIDP QA +W+KT K + L+V+ D N++ +E
Sbjct: 636 LPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELA 695
Query: 2799 LEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRN 2858
+ +GK +I ++ VE L P+L + QG + + +GD +I+Y+ FRL+++T+ N
Sbjct: 696 VRFGKTLIIQ-EMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPN 754
Query: 2859 PHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQV 2918
P P+ + VT +NF T+ GL Q L + + E+PDL+E++ KL+ Q + L ++
Sbjct: 755 PFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKL 814
Query: 2919 EDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIA 2978
E+ +L TL ++G+ILE++ IE L+ +K + I + + S + + +++ R Y P+A
Sbjct: 815 EESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLA 874
Query: 2979 SHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLY 3038
++ +Y+ +++L ++ MY++SL F+ L+ +++N S++ E+R++ L + + +Y
Sbjct: 875 ESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVY 934
Query: 3039 SNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNV-DEYKFLITGGIAVENHLKKPV-EWLPD 3096
+CR LF D+LMF+ M + N D + ++ G + + ++ + + LP
Sbjct: 935 EYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLP- 993
Query: 3097 KAWDEICRLNDLKAFRAFRDDFVKTII-----KWQEVYDDIEPQNKTLPGGWDERLTQFQ 3151
+W + R + + +T+ W+ Y++ + + P ++++ FQ
Sbjct: 994 -SWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQE-FPSILAKKVSLFQ 1051
Query: 3152 KLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDP 3211
++LVV+VLRPD+L A++ F K +G K +P P ++ + + ++ + P++ I+SPG+DP
Sbjct: 1052 QILVVQVLRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADP 1111
Query: 3212 MGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLE 3271
L + ++ +++GQGQ +A M+++ G W+CL+N HL VSWLPVLE
Sbjct: 1112 SQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLE 1171
Query: 3272 KIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLK 3331
K + +T FRLWLT+ F +LQ +K+T E P GL+ NL R+Y
Sbjct: 1172 KELNTLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY------ 1222
Query: 3332 EPEFYEGCPGKDKTF-SKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQ 3390
E E KD T + L+ +++FHA QER+ + P GW Y F+ SD + +
Sbjct: 1223 ESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIID 1282
Query: 3391 MFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELG 3450
+ +++Q+ + L YGGR+ + +D R++ + L + NS V++ N +
Sbjct: 1283 RLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSI 1342
Query: 3451 QQY--GLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXX 3508
Y LP+ C DY IE +P + P FGL N + IS ++ S L +
Sbjct: 1343 FPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQL-RILGR 1401
Query: 3509 XXXXXXXXXXXILVLMASEILS---KLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFN 3565
I S +L+ KL ++ I QK P + + + +E+FN
Sbjct: 1402 SITAGSKFDREIWSNELSPVLNLWKKLNQNSNL-IHQKVPPPNDRQGSPILSFIILEQFN 1460
Query: 3566 --KLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWR-KFSYPSLKPLPSY 3622
+L+ + SL L K ++G ++S + ++A+L K P W+ K+ P PL Y
Sbjct: 1461 AIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPE-DPL-QY 1518
Query: 3623 VADFIERLSMLEDWYQNGK-----PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF 3677
+ + R +++W + T L F FL Q ARA +D L F
Sbjct: 1519 LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF 1578
Query: 3678 --DFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKL 3735
++ R + + G+ ++G DG + + E + + VL M W+
Sbjct: 1579 VASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS-ENQLDSPSVSSVLPCFMG--WIPQDA 1635
Query: 3736 KNEFNEGTRYKCPLYKTLERKGVL 3759
++ P+Y + ER V+
Sbjct: 1636 CGPYSPDECISLPVYTSAERDRVV 1659
>BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein
protein.
Length = 1732
Score = 568 bits (1402), Expect = e-160
Identities = 437/1713 (25%), Positives = 788/1713 (46%), Gaps = 86/1713 (5%)
Query: 2084 MTIVLFDYALEHLSKICRILSMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKS 2143
+ I+LF LE++S+I R+LS P G+ LL G G GR+++T L S + G +F P+I++
Sbjct: 43 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 102
Query: 2144 YSVKDWHDDIKLVLRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEK 2203
Y +K + +D+K VL+ +G + L + Q ++++ ++SLL+SGEVP LY L+E
Sbjct: 103 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 162
Query: 2204 QEIL-ELVRLAAQGGNRNLDISPLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPS 2262
+ +L L A+Q G P + +F R + LHIVL S+F P+
Sbjct: 163 EPLLLPLKDQASQDGF----FGP--VFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPA 216
Query: 2263 LVNCCTIDWYDSWPEDALEMVAHHYMVKVNVPDPVKSSAVIACKQFH-VDARIVSIDFFN 2321
L C + W + W +++ + + + K+ + VD +
Sbjct: 217 LHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLI 276
Query: 2322 HFGRETY-ITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDL 2380
H + Y T + Y+ + ++ +++ K++EL + G+ +L +A V + R
Sbjct: 277 HESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKA 336
Query: 2381 NALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADL 2440
L +++ +Q I V A + ++ + E K + +L
Sbjct: 337 GEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDEL 396
Query: 2441 ALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXX 2500
P++ +A A+ +KP ++ ++S++ PP ++ ++ V
Sbjct: 397 KEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVL---------------RL 441
Query: 2501 XXMFDF-WGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNK-DFKPHIVAKAS 2558
+FD W K L G + + FD NI + + + NK F P +AS
Sbjct: 442 MGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRAS 501
Query: 2559 AAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXX 2618
AA L W+ Y +T + + ++
Sbjct: 502 TAAAPLAAWVKVNIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSE 561
Query: 2619 XXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGD 2678
+ LE EV + + AE LI L E RW + L
Sbjct: 562 LKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKR 621
Query: 2679 ILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAG 2738
++ I YL+ +R +++W E+F + L T+ + W G
Sbjct: 622 AQLAAAFITYLSAAPESLRKTCLEEWT------KSAGLEKFDLRRFLCTESEQLIWKSEG 675
Query: 2739 LPRDLFSIDNA--IIQDNSMR-WS----LLIDPQGQANKWIKTMEKTNDLQVLKFTDGNY 2791
LP D SI+NA I+Q ++ WS LIDP QA +W+KT K + L+V+ D N+
Sbjct: 676 LPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNF 735
Query: 2792 MKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLY 2851
+ +E + +GK +I ++ VE L P+L + QG + + +GD +I+Y+ FRL+
Sbjct: 736 ITALELAVRFGKTLIIQ-EMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLF 794
Query: 2852 MTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAAN 2911
++T+ NP P+ + VT +NF T+ GL Q L + + E+PDL+E++ KL+ Q
Sbjct: 795 LSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDK 854
Query: 2912 RAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFR 2971
+ L ++E+ +L TL ++G+ILE++ IE L+ +K + I + + S + + +++ R
Sbjct: 855 KIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQER 914
Query: 2972 LGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKD 3031
Y P+A ++ +Y+ +++L ++ MY++SL F+ L+ +++N S++ E+R++ L
Sbjct: 915 DAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLIS 974
Query: 3032 TFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNV-DEYKFLITGGIAVENHLKKP 3090
+ + +Y +CR LF D+LMF+ M + N D + ++ G + + ++
Sbjct: 975 SLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQK 1034
Query: 3091 V-EWLPDKAWDEICRLNDLKAFRAFRDDFVKTII-----KWQEVYDD--IEPQNKTLPGG 3142
+ + LP +W + R + + +T+ W+ Y++ E + ++P
Sbjct: 1035 IRDQLP--SWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQEFPSIPA- 1091
Query: 3143 WDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLI 3202
++++ FQ++LVV+ LRPD+L A++ F K +G K +P P ++ + + ++ + P++
Sbjct: 1092 --KKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPIL 1149
Query: 3203 FILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHL 3262
I+SPG+DP L + ++ +++GQGQ +A M+++ G W+CL+N HL
Sbjct: 1150 IIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHL 1209
Query: 3263 AVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLN 3322
VSWLPVLEK + +T FRLWLT+ F +LQ +K+T E P GL+ NL
Sbjct: 1210 VVSWLPVLEKELNTLQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLM 1266
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTF-SKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSD 3381
R+Y E E KD T + L+ +++FHA QER+ + P GW Y F+ SD
Sbjct: 1267 RTY------ESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSD 1320
Query: 3382 FQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVND 3441
+ + + +++Q+ + L YGGR+ + +D R++ + L + NS V++
Sbjct: 1321 LRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDV 1380
Query: 3442 PNYLFCELGQQY--GLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELT 3499
N + Y LP+ C DY IE +P + P FGL N + IS ++
Sbjct: 1381 FNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVI 1440
Query: 3500 SSLVLVXXXXXXXXXXXXXXILVLMASEILS---KLPPKFDVEIAQKKYPVDYNESMNTV 3556
S L + I S +L+ KL ++ I QK P + + +
Sbjct: 1441 SQL-RILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNL-IHQKVPPPNDRQGSPIL 1498
Query: 3557 LIQEMERFN--KLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWR-KFSY 3613
+E+FN +L+ + SL L K ++G ++S + ++A+L K P W+ K+
Sbjct: 1499 SFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEG 1558
Query: 3614 PSLKPLPSYVADFIERLSMLEDWYQNGK-----PPTFWLPGFFFTQAFLTGSVQNYARAK 3668
P PL Y+ + R +++W + T L F FL Q ARA
Sbjct: 1559 PE-DPL-QYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAV 1616
Query: 3669 TIPIDLLVF--DFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNM 3726
+D L F ++ R + + G+ ++G DG + + E + + VL M
Sbjct: 1617 GRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS-ENQLDSPSVSSVLPCFM 1675
Query: 3727 PVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVL 3759
W+ ++ P+Y + ER V+
Sbjct: 1676 G--WIPQDACGPYSPDECISLPVYTSAERDRVV 1706
>AL117428-1|CAB55917.1| 591|Homo sapiens hypothetical protein
protein.
Length = 591
Score = 560 bits (1383), Expect = e-158
Identities = 275/595 (46%), Positives = 376/595 (63%), Gaps = 7/595 (1%)
Query: 3203 FILSPGSDPMGALIKYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHL 3262
F+LSPG+DP L K+ E M FS + ++ISLGQGQGP A AM+ + G WV QNCHL
Sbjct: 1 FVLSPGTDPAADLYKFAEEMKFSKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHL 60
Query: 3263 AVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLN 3322
A SW+P LE+++E + FRLWLTS PS+KFP S+LQ G KMT EPP G++ NL
Sbjct: 61 APSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANLL 120
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDF 3382
+SY S L E +F C K F LL + FH ER+KFGPLG+NI Y F D D
Sbjct: 121 KSYSS--LGE-DFLNSCH-KVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDL 176
Query: 3383 QISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDP 3442
+I + QL+MFL++Y++I Y +KY GE NYGGRVTDDWDRR I+ IL+++ N V++ P
Sbjct: 177 RICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLS-P 235
Query: 3443 NYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSL 3502
+ + G + +P + YL +I+S+P+N PE+FGLH NA IT + + L ++
Sbjct: 236 EHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTI 295
Query: 3503 VLVXXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEME 3562
+ + I+ + IL K+P +++ KYPV Y ESMNTVL+QE+
Sbjct: 296 IQLQPKSSSAGSQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVI 355
Query: 3563 RFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSY 3622
R+N+LL I +LQDL KA+KGL+VMS L+L + ++ +PE W +YPSLKPL S+
Sbjct: 356 RYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSW 415
Query: 3623 VADFIERLSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIR 3682
V D ++RL L+ W Q+G P FW+ GFFF QAFLTG++QN+AR I ID + FDF++
Sbjct: 416 VMDLLQRLDFLQAWIQDGIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVM 475
Query: 3683 -NVDYETTP-PKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFN 3740
E T P+ G ++ GLF++G RW+ E +AE PK L M VIWL P +
Sbjct: 476 FEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQ 535
Query: 3741 EGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQLD 3795
+ Y CP+YKTL R G L+TTGHS+N+V+A +P+ +P HWIKR VAL+ LD
Sbjct: 536 DQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALICALD 590
>AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, heavy
polypeptide 1 protein.
Length = 4646
Score = 548 bits (1353), Expect = e-154
Identities = 409/1611 (25%), Positives = 737/1611 (45%), Gaps = 104/1611 (6%)
Query: 1926 AATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGC-ALLRKESADNKKTFIKIWIHEI 1984
AA + Y ++E + HYI++ R+ +R ++G LR + I+IW HE
Sbjct: 2771 AAMVEFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEA 2829
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
+R+F DRLV+D++R W D DT AL+ + + E + +++ +
Sbjct: 2830 LRLFQDRLVEDEERRW---------TDENIDTV--ALKHFPNIDREKAMS--RPILYSNW 2876
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
L D Y + +E+ + + Y + + +VLF+ L+H+ +I RI
Sbjct: 2877 LSKD-------YIPVDQEELRDYVKARLKVFYEE--ELDVPLVLFNEVLDHVLRIDRIFR 2927
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
P G+ LL+GV G+G+ +L+R + + G V+Q ++ + Y+ +D+ +D++ VLR SG N
Sbjct: 2928 QPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKN 2987
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
+ F+ ES + + +++ +++LL +GEVP L+ DE ++ + AQ LD S
Sbjct: 2988 EKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLD-S 3046
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
++ +F + LH+V +P + R P+L N C ++W+ W +AL V
Sbjct: 3047 HEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVG 3106
Query: 2285 HHYMVKVN-------VPD--PV-----------KSSAVIACKQFHVDARIVSIDFFNHFG 2324
+ K++ VPD PV + + V +C H + G
Sbjct: 3107 KEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGG 3166
Query: 2325 RETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALK 2384
R IT YLD I + L + K+ EL ++ GL ++ + D V ++RDL
Sbjct: 3167 RTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKS 3226
Query: 2385 PQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALAL 2444
+L V + ++++ + A+K +E Q+ + + + DL
Sbjct: 3227 QELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVE 3286
Query: 2445 PILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMF 2504
P + +A A+ ++K + V+SM NPP VKL + ++C+
Sbjct: 3287 PAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD------------ 3334
Query: 2505 DFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGL 2564
W + I+ F+ ++ NF + I A +K++K Y+SN + IV +AS A +
Sbjct: 3335 --WKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPM 3392
Query: 2565 CKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXX 2624
KW IA Y E + M+
Sbjct: 3393 VKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYA 3452
Query: 2625 XXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCG 2684
+ +A++ ++ K+ R+ L+ L E+ RW +E + +AGD L+S
Sbjct: 3453 VLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAA 3512
Query: 2685 IIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLF 2744
IAY + +R + W + + N+ + L + W + LP D
Sbjct: 3513 FIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDL 3572
Query: 2745 SIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKP 2804
+NAI+ R+ L+IDP GQA ++I K + F D + K +E+ L +G P
Sbjct: 3573 CTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNP 3632
Query: 2805 ALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPE 2864
L+ V E + L+PVL + GG+ I LGD I+ P+F ++++T+ + P+
Sbjct: 3633 LLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPD 3691
Query: 2865 IFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILR 2924
+ ++VT +NF +T+ L+ Q L V+ ERPD+ EKR L+ + L+Q+E +L+
Sbjct: 3692 LCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQ 3751
Query: 2925 TLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVL 2984
L E KG IL+D++ I L++ K A ++ +K E + +E Y P+++ + +
Sbjct: 3752 ALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSI 3811
Query: 2985 YYCVTELPNVDPMYQYSLTWFINLY-IISIENANKS--KDLEKRLKFL-KDTFTYNLYSN 3040
Y+ + L + +YQYSL +F+++Y + EN N D +RL + KD F ++
Sbjct: 3812 YFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQV-AFNR 3870
Query: 3041 VCRSLFDKDKLMFSFIMCSKMMLST--EKMNVDEYKFLITGGIAVENHLKKP-VEWLPDK 3097
V R + +D + F+ ++ + T E E++ + G V + P ++ L +
Sbjct: 3871 VARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVE 3930
Query: 3098 AWDEICRLNDLKAFRAFRDDFVKTIIKWQ-EVYDDIEPQNKTLPGGWDERL------TQF 3150
+ + RL+ L AF+D K Q ++ D +T+P W E
Sbjct: 3931 QAEAVVRLSCLP---AFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAI 3987
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT--PPPFDISKSFG-DSNCLAPLIFILSP 3207
+LL+++ RPD+L F+ +G + + P D++ G + P++ P
Sbjct: 3988 HRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVP 4047
Query: 3208 GSDPMGALIKYCERMGFSHRFNSISLGQGQG-PIARAMIEKAQSEGGWVCLQNCHLAVSW 3266
G D G + + + SI++G +G A I A G WV L+N HLA W
Sbjct: 4048 GYDASGHVEDLAAEQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGW 4105
Query: 3267 LPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYI 3326
L LEK + FRL+LT + K P ++L+ G EPP G++ N+ R++
Sbjct: 4106 LMQLEKKLHSL---QPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFS 4162
Query: 3327 SEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISV 3386
S P+ C ++ ++L + +++FHA++QER ++ PLGW+ +Y F +SD + +
Sbjct: 4163 SIPVSRI-----CKSPNER-ARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSAC 4216
Query: 3387 MQLQMFLNQY---------EEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSG 3437
+ +L+ ++I + A+K L + YGGRV +++D+RL+ T L+ +
Sbjct: 4217 DTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTR 4276
Query: 3438 VVNDPNYLFCELG--QQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNA 3486
+ L C++ + +P +++++ +E +P P GL NA
Sbjct: 4277 SFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNA 4327
Score = 266 bits (651), Expect = 1e-69
Identities = 162/493 (32%), Positives = 265/493 (53%), Gaps = 29/493 (5%)
Query: 815 EIISVAATKELALITNLNK--MMAEW--IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWY 870
+I V T EL L+ NK ++ W + + + +HI M+ S + K FE +W
Sbjct: 1465 QIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWE 1524
Query: 871 EKIVRVNATIDEWGKVQSQWLYLLPIFS-SKDIVAQMPEEGVMFVEVNNIYRRYMGSVDK 929
+K+ R+ A D W VQ +W+YL IF+ S DI +P E F ++ + M V K
Sbjct: 1525 DKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 1584
Query: 930 DPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSET 989
P V+++ G+ + L KI + YLE++R FPRF+F+ ++++LEI+ +
Sbjct: 1585 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNS 1644
Query: 990 KNPLKVQPHLKKCFEGINRLVFDGEFNISAMISM-EGEQVEFLDMISVAAARGSVEKWLV 1048
KN K+Q H KK F G++ ++ + + ++ IS EGE+V F +S+ + +WL
Sbjct: 1645 KNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINEWLT 1703
Query: 1049 QVEEQMLKAV-----KSETEISYYDY-----PNMGRVEWVLSWEGMVVLAISQIYWAVDV 1098
VE++M + +S TE+ + PN + W+ ++ +V+ +QI W+ +V
Sbjct: 1704 LVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNT-YITWIDKYQAQLVVLSAQIAWSENV 1762
Query: 1099 HESLNTHKLS-ELQAFHSELTKQLNETVAVIRRTDLTK---LSSITVKALIVIDVHAKDV 1154
+L++ + HS L+ + T+ V+ + L + L ++ LI VH +DV
Sbjct: 1763 ETALSSMGGGGDAAPLHSVLSN-VEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDV 1821
Query: 1155 ISDLIKKKVTEVTDFQWLAQLRYYWEE------ERVYVKIINAVVHYAYEYLGNSDRLVI 1208
LIK K+ F+WL+Q+R+Y++ +++ +++ NA +Y +EYLG D+LV
Sbjct: 1822 TRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQ 1881
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY T+ A L G+P GPAGTGKTE+ K L L +VFNC + D++AM
Sbjct: 1882 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 1941
Query: 1269 GKFFKGLASCGAW 1281
G+ F GL GAW
Sbjct: 1942 GRIFVGLCQVGAW 1954
Score = 219 bits (534), Expect = 2e-55
Identities = 140/393 (35%), Positives = 212/393 (53%), Gaps = 64/393 (16%)
Query: 1297 LKLNPACYVCITMNPGYAGRSELPDNLKVLF-----------------------RTVAMM 1333
+K++P + ITMNPGYAGRS LPDNLK LF RT ++
Sbjct: 2006 VKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVL 2065
Query: 1334 ----VPDYAMI-EQLSSQNHYDYGMRAVKTVLSAAGNLKRS------------------- 1369
VP + + EQLSSQ+HYD+G+RA+K+VL +AGN+KR
Sbjct: 2066 ANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEG 2125
Query: 1370 --FPNESESVLLLRSITDVNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDV 1427
N E +L++S+ + +PK ++ D+PL ++SD+FPG+ + + V
Sbjct: 2126 EIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKV 2185
Query: 1428 CENNNLQPME------CFLIKVIQTYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIH 1481
C+ L + ++ KV+Q Y++ + HG M+VG SGKSM +VL +AL +
Sbjct: 2186 CQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERL- 2244
Query: 1482 ERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDGIVATMFREFASE---DTPVRK 1538
+G E +++PKA++ LYG DP + EWTDG+ + R+ + R+
Sbjct: 2245 -----EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQ 2299
Query: 1539 WIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSMIFEVMDLSQASPATVSRC 1598
WIVFDG VD W+EN+N+VLDDNK L L +GE +++ + ++FEV DL A+ ATVSRC
Sbjct: 2300 WIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRC 2359
Query: 1599 GMIYMESTSLGFMPFYKSWLNTLNPIWLEENEE 1631
GM++ L + ++L L I L+E E+
Sbjct: 2360 GMVWFSEDVLSTDMIFNNFLARLRSIPLDEGED 2392
Score = 66.9 bits (156), Expect = 1e-09
Identities = 68/241 (28%), Positives = 108/241 (44%), Gaps = 23/241 (9%)
Query: 1696 LMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDHFYMYK 1755
L+ AI+W L G DSR K + EY + +P +IP +ID+
Sbjct: 2494 LVYAILWSLSG----DSRLKMRAELGEYIRRITTVPLPTAP---NIP----IIDYEVSIS 2542
Query: 1756 GKGCWKTWPDAVKAVQVK-EQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGPTGTG 1814
G+ W W V ++V+ ++ V+PTL+T + LL KPL+L GP G+G
Sbjct: 2543 GE--WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSG 2600
Query: 1815 KSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNN--YGPTR-GKH 1871
K+ + + L DME F +T D +R N P + GK
Sbjct: 2601 KTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE--YRRTPNGVVLAPVQLGKW 2658
Query: 1872 AIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFI-YDTI-FYGAIAATT 1929
++F D++N+P + YG Q I +R + +Y +T+D+ ++ + I F GA T
Sbjct: 2659 LVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY--RTSDQTWVKLERIQFVGACNPPT 2716
Query: 1930 D 1930
D
Sbjct: 2717 D 2717
Score = 45.2 bits (102), Expect = 0.005
Identities = 44/212 (20%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 3559 QEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKP 3618
+E++ KLL +++ L D+ + +G + L N ++ G +P +W ++ P+
Sbjct: 4415 REVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMT 4474
Query: 3619 LPSYVADFIERLSMLED--------WYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTI 3670
+ +V+DF ER+ L++ + K L G F +A++T + Q A+A +
Sbjct: 4475 VIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSW 4534
Query: 3671 PIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIW 3730
++ L + + T V GL + G N +++ + L P+
Sbjct: 4535 SLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTAL----PLTQ 4589
Query: 3731 L-YPKLKNEFNEGTRYKCPLYKTLERKGVLAT 3761
L + K N + + P+Y R ++ T
Sbjct: 4590 LRWVKQTNTEKKASVVTLPVYLNFTRADLIFT 4621
>AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein.
Length = 4658
Score = 548 bits (1353), Expect = e-154
Identities = 409/1611 (25%), Positives = 737/1611 (45%), Gaps = 104/1611 (6%)
Query: 1926 AATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGC-ALLRKESADNKKTFIKIWIHEI 1984
AA + Y ++E + HYI++ R+ +R ++G LR + I+IW HE
Sbjct: 2783 AAMVEFYTMSQERFTQD-TQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEA 2841
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
+R+F DRLV+D++R W D DT AL+ + + E + +++ +
Sbjct: 2842 LRLFQDRLVEDEERRW---------TDENIDTV--ALKHFPNIDREKAMS--RPILYSNW 2888
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
L D Y + +E+ + + Y + + +VLF+ L+H+ +I RI
Sbjct: 2889 LSKD-------YIPVDQEELRDYVKARLKVFYEE--ELDVPLVLFNEVLDHVLRIDRIFR 2939
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
P G+ LL+GV G+G+ +L+R + + G V+Q ++ + Y+ +D+ +D++ VLR SG N
Sbjct: 2940 QPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKN 2999
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
+ F+ ES + + +++ +++LL +GEVP L+ DE ++ + AQ LD S
Sbjct: 3000 EKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLD-S 3058
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
++ +F + LH+V +P + R P+L N C ++W+ W +AL V
Sbjct: 3059 HEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVG 3118
Query: 2285 HHYMVKVN-------VPD--PV-----------KSSAVIACKQFHVDARIVSIDFFNHFG 2324
+ K++ VPD PV + + V +C H + G
Sbjct: 3119 KEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGG 3178
Query: 2325 RETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVAIMQRDLNALK 2384
R IT YLD I + L + K+ EL ++ GL ++ + D V ++RDL
Sbjct: 3179 RTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKS 3238
Query: 2385 PQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKKDCEADLALAL 2444
+L V + ++++ + A+K +E Q+ + + + DL
Sbjct: 3239 QELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVE 3298
Query: 2445 PILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXXXXXXXXXXMF 2504
P + +A A+ ++K + V+SM NPP VKL + ++C+
Sbjct: 3299 PAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTD------------ 3346
Query: 2505 DFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIVAKASAAAEGL 2564
W + I+ F+ ++ NF + I A +K++K Y+SN + IV +AS A +
Sbjct: 3347 --WKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPM 3404
Query: 2565 CKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXX 2624
KW IA Y E + M+
Sbjct: 3405 VKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYA 3464
Query: 2625 XXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCG 2684
+ +A++ ++ K+ R+ L+ L E+ RW +E + +AGD L+S
Sbjct: 3465 VLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAA 3524
Query: 2685 IIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLF 2744
IAY + +R + W + + N+ + L + W + LP D
Sbjct: 3525 FIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDL 3584
Query: 2745 SIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKP 2804
+NAI+ R+ L+IDP GQA ++I K + F D + K +E+ L +G P
Sbjct: 3585 CTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNP 3644
Query: 2805 ALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPE 2864
L+ V E + L+PVL + GG+ I LGD I+ P+F ++++T+ + P+
Sbjct: 3645 LLVQDV-ESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPD 3703
Query: 2865 IFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILR 2924
+ ++VT +NF +T+ L+ Q L V+ ERPD+ EKR L+ + L+Q+E +L+
Sbjct: 3704 LCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQ 3763
Query: 2925 TLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVL 2984
L E KG IL+D++ I L++ K A ++ +K E + +E Y P+++ + +
Sbjct: 3764 ALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSI 3823
Query: 2985 YYCVTELPNVDPMYQYSLTWFINLY-IISIENANKS--KDLEKRLKFL-KDTFTYNLYSN 3040
Y+ + L + +YQYSL +F+++Y + EN N D +RL + KD F ++
Sbjct: 3824 YFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQV-AFNR 3882
Query: 3041 VCRSLFDKDKLMFSFIMCSKMMLST--EKMNVDEYKFLITGGIAVENHLKKP-VEWLPDK 3097
V R + +D + F+ ++ + T E E++ + G V + P ++ L +
Sbjct: 3883 VARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVE 3942
Query: 3098 AWDEICRLNDLKAFRAFRDDFVKTIIKWQ-EVYDDIEPQNKTLPGGWDERL------TQF 3150
+ + RL+ L AF+D K Q ++ D +T+P W E
Sbjct: 3943 QAEAVVRLSCLP---AFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAI 3999
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTT--PPPFDISKSFG-DSNCLAPLIFILSP 3207
+LL+++ RPD+L F+ +G + + P D++ G + P++ P
Sbjct: 4000 HRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVP 4059
Query: 3208 GSDPMGALIKYCERMGFSHRFNSISLGQGQG-PIARAMIEKAQSEGGWVCLQNCHLAVSW 3266
G D G + + + SI++G +G A I A G WV L+N HLA W
Sbjct: 4060 GYDASGHVEDLAAEQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGW 4117
Query: 3267 LPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYI 3326
L LEK + FRL+LT + K P ++L+ G EPP G++ N+ R++
Sbjct: 4118 LMQLEKKLHSL---QPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFS 4174
Query: 3327 SEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISV 3386
S P+ C ++ ++L + +++FHA++QER ++ PLGW+ +Y F +SD + +
Sbjct: 4175 SIPVSRI-----CKSPNER-ARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSAC 4228
Query: 3387 MQLQMFLNQY---------EEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSG 3437
+ +L+ ++I + A+K L + YGGRV +++D+RL+ T L+ +
Sbjct: 4229 DTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTR 4288
Query: 3438 VVNDPNYLFCELG--QQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNA 3486
+ L C++ + +P +++++ +E +P P GL NA
Sbjct: 4289 SFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNA 4339
Score = 266 bits (651), Expect = 1e-69
Identities = 162/493 (32%), Positives = 265/493 (53%), Gaps = 29/493 (5%)
Query: 815 EIISVAATKELALITNLNK--MMAEW--IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWY 870
+I V T EL L+ NK ++ W + + + +HI M+ S + K FE +W
Sbjct: 1477 QIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWE 1536
Query: 871 EKIVRVNATIDEWGKVQSQWLYLLPIFS-SKDIVAQMPEEGVMFVEVNNIYRRYMGSVDK 929
+K+ R+ A D W VQ +W+YL IF+ S DI +P E F ++ + M V K
Sbjct: 1537 DKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 1596
Query: 930 DPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSET 989
P V+++ G+ + L KI + YLE++R FPRF+F+ ++++LEI+ +
Sbjct: 1597 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNS 1656
Query: 990 KNPLKVQPHLKKCFEGINRLVFDGEFNISAMISM-EGEQVEFLDMISVAAARGSVEKWLV 1048
KN K+Q H KK F G++ ++ + + ++ IS EGE+V F +S+ + +WL
Sbjct: 1657 KNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINEWLT 1715
Query: 1049 QVEEQMLKAV-----KSETEISYYDY-----PNMGRVEWVLSWEGMVVLAISQIYWAVDV 1098
VE++M + +S TE+ + PN + W+ ++ +V+ +QI W+ +V
Sbjct: 1716 LVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNT-YITWIDKYQAQLVVLSAQIAWSENV 1774
Query: 1099 HESLNTHKLS-ELQAFHSELTKQLNETVAVIRRTDLTK---LSSITVKALIVIDVHAKDV 1154
+L++ + HS L+ + T+ V+ + L + L ++ LI VH +DV
Sbjct: 1775 ETALSSMGGGGDAAPLHSVLSN-VEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDV 1833
Query: 1155 ISDLIKKKVTEVTDFQWLAQLRYYWEE------ERVYVKIINAVVHYAYEYLGNSDRLVI 1208
LIK K+ F+WL+Q+R+Y++ +++ +++ NA +Y +EYLG D+LV
Sbjct: 1834 TRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQ 1893
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY T+ A L G+P GPAGTGKTE+ K L L +VFNC + D++AM
Sbjct: 1894 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 1953
Query: 1269 GKFFKGLASCGAW 1281
G+ F GL GAW
Sbjct: 1954 GRIFVGLCQVGAW 1966
Score = 219 bits (534), Expect = 2e-55
Identities = 140/393 (35%), Positives = 212/393 (53%), Gaps = 64/393 (16%)
Query: 1297 LKLNPACYVCITMNPGYAGRSELPDNLKVLF-----------------------RTVAMM 1333
+K++P + ITMNPGYAGRS LPDNLK LF RT ++
Sbjct: 2018 VKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVL 2077
Query: 1334 ----VPDYAMI-EQLSSQNHYDYGMRAVKTVLSAAGNLKRS------------------- 1369
VP + + EQLSSQ+HYD+G+RA+K+VL +AGN+KR
Sbjct: 2078 ANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEG 2137
Query: 1370 --FPNESESVLLLRSITDVNLPKFLSFDVPLFEGIISDLFPGISLPKPDYENFLNACHDV 1427
N E +L++S+ + +PK ++ D+PL ++SD+FPG+ + + V
Sbjct: 2138 EIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKV 2197
Query: 1428 CENNNLQPME------CFLIKVIQTYEMMIVRHGFMLVGNPFSGKSMTLKVLSEALSLIH 1481
C+ L + ++ KV+Q Y++ + HG M+VG SGKSM +VL +AL +
Sbjct: 2198 CQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERL- 2256
Query: 1482 ERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDGIVATMFREFASE---DTPVRK 1538
+G E +++PKA++ LYG DP + EWTDG+ + R+ + R+
Sbjct: 2257 -----EGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQ 2311
Query: 1539 WIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSMIFEVMDLSQASPATVSRC 1598
WIVFDG VD W+EN+N+VLDDNK L L +GE +++ + ++FEV DL A+ ATVSRC
Sbjct: 2312 WIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRC 2371
Query: 1599 GMIYMESTSLGFMPFYKSWLNTLNPIWLEENEE 1631
GM++ L + ++L L I L+E E+
Sbjct: 2372 GMVWFSEDVLSTDMIFNNFLARLRSIPLDEGED 2404
Score = 66.9 bits (156), Expect = 1e-09
Identities = 68/241 (28%), Positives = 108/241 (44%), Gaps = 23/241 (9%)
Query: 1696 LMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDHFYMYK 1755
L+ AI+W L G DSR K + EY + +P +IP +ID+
Sbjct: 2506 LVYAILWSLSG----DSRLKMRAELGEYIRRITTVPLPTAP---NIP----IIDYEVSIS 2554
Query: 1756 GKGCWKTWPDAVKAVQVK-EQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGPTGTG 1814
G+ W W V ++V+ ++ V+PTL+T + LL KPL+L GP G+G
Sbjct: 2555 GE--WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSG 2612
Query: 1815 KSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNN--YGPTR-GKH 1871
K+ + + L DME F +T D +R N P + GK
Sbjct: 2613 KTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE--YRRTPNGVVLAPVQLGKW 2670
Query: 1872 AIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFI-YDTI-FYGAIAATT 1929
++F D++N+P + YG Q I +R + +Y +T+D+ ++ + I F GA T
Sbjct: 2671 LVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY--RTSDQTWVKLERIQFVGACNPPT 2728
Query: 1930 D 1930
D
Sbjct: 2729 D 2729
Score = 45.2 bits (102), Expect = 0.005
Identities = 44/212 (20%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 3559 QEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKP 3618
+E++ KLL +++ L D+ + +G + L N ++ G +P +W ++ P+
Sbjct: 4427 REVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMT 4486
Query: 3619 LPSYVADFIERLSMLED--------WYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTI 3670
+ +V+DF ER+ L++ + K L G F +A++T + Q A+A +
Sbjct: 4487 VIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSW 4546
Query: 3671 PIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIW 3730
++ L + + T V GL + G N +++ + L P+
Sbjct: 4547 SLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTAL----PLTQ 4601
Query: 3731 L-YPKLKNEFNEGTRYKCPLYKTLERKGVLAT 3761
L + K N + + P+Y R ++ T
Sbjct: 4602 LRWVKQTNTEKKASVVTLPVYLNFTRADLIFT 4633
>AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1031
Score = 530 bits (1308), Expect = e-149
Identities = 320/1037 (30%), Positives = 539/1037 (51%), Gaps = 29/1037 (2%)
Query: 2298 KSSAVIACKQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKL 2357
K S + H +S ++ + R Y T S+L+ I F L +KQ E+ K
Sbjct: 4 KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKE 63
Query: 2358 RYTNGLDQLGQAADAVAIMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVRE 2417
R NG+ +L A V ++ L + + +L + + ++ +I ++T +
Sbjct: 64 RLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADA 123
Query: 2418 DQKXXXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKL 2477
+++ + +++CEADL A P L A AALNTL +++ +K+ NPP V
Sbjct: 124 EERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTN 183
Query: 2478 VMAAVCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMG-FLDSLKNFDKDNIPVATM 2536
V AAV V W +K +G + FL +L N+DK++IP +
Sbjct: 184 VTAAVMVLLAPRGRVPKDRS---------WKAAKVFMGKVDDFLQALINYDKEHIPENCL 234
Query: 2537 QKIRKEYLSNKDFKPHIVAKASAAAEGLCKWII-AMDMYDXXXXXXXXXXXXXXXXXXXX 2595
+ + + YL + +F P+++ S AA GLC W+I + Y+
Sbjct: 235 KVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELA 294
Query: 2596 XQTMAILEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLG 2655
T + +K +V +K ++EV + A +L+ L
Sbjct: 295 AATEKLEAIRKKLVDLDRNLSRLTASFEKAT-AEKVRCQEEVNQTNKTIKLANRLVKELE 353
Query: 2656 GEKVRWTVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIID-KWRD-LVIKLNM 2713
+K+RW + ++ + L GD+L++ ++Y+ P+T R E++ KW L K+++
Sbjct: 354 AKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSI 413
Query: 2714 PHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIK 2773
P +E +L D I W GLP D S +NA I + RW L+IDPQ Q KWIK
Sbjct: 414 PLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIK 473
Query: 2774 TMEKTNDLQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKE 2833
+ DL+V ++ IET L +G LI+ + E ++ LDP+L + T +G +
Sbjct: 474 N-KYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKG--K 530
Query: 2834 FIALGDNVIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKE 2893
+I +GD E++ NFRL + TKL NPHY PE+ + TL+NF +T+DGLE Q L VV+ E
Sbjct: 531 YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIE 590
Query: 2894 RPDLQEKREKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDI 2953
RPDL++ + L + LK +EDD+L L +G L+D +E L+++K +I
Sbjct: 591 RPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEI 650
Query: 2954 MKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISI 3013
K + E E I + R YRP+A+ +++LY+ + +L ++P+YQ+SL F L+ +I
Sbjct: 651 EHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAI 710
Query: 3014 ENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEY 3073
E A+K +D++ R+ L ++ T+ ++ ++LF+KDKL F M +++L ++++ E
Sbjct: 711 EQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLEL 770
Query: 3074 KFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIE 3133
FL+ VE+ PV++L ++W I + ++ FR D + +W++ +
Sbjct: 771 DFLLR--FTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESEC 828
Query: 3134 PQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFG 3193
P+ + LP W ++ + QKL+++R +RPD++T A+ F+E+++G KY D+ K+F
Sbjct: 829 PEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFE 887
Query: 3194 DSNCLAPLIFILSPGSDPMGALIKYCERMGF---SHRFNSISLGQGQGPIARAMIEKAQS 3250
+S+ P+ FILSPG D + L +R+GF S +F+++SLGQGQ +A +EKA
Sbjct: 888 ESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASK 947
Query: 3251 EGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLT--SYPSDK---FPQSVLQV 3305
G WV LQN HL WL LEK++E F + +R++++ S P+ PQ +L+
Sbjct: 948 GGHWVILQNVHLVAKWLGTLEKLLERFS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLEN 1006
Query: 3306 GVKMTNEPPTGLQHNLN 3322
+K+TNEPPTG+ NL+
Sbjct: 1007 SIKITNEPPTGMLANLH 1023
>AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein.
Length = 1270
Score = 520 bits (1282), Expect = e-146
Identities = 327/1126 (29%), Positives = 574/1126 (50%), Gaps = 75/1126 (6%)
Query: 101 PMLKSWERKIRNLIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTVIRDV--PGVPR 158
PM SW + +L+P +L+ F + L +E ++++ ++ V V++D G +
Sbjct: 174 PMEDSWLEHVLDLVPQHLKV-FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDK 232
Query: 159 KRYEEPHFK--FKGVTSNYGK-LLKYRRKLQDGSLLLHPFIRLILESSEKTFP-LHIIDL 214
K E P + + + + K L ++D ++P + +L+ F L ++D+
Sbjct: 233 KTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDI 292
Query: 215 AKYR-AKGPMSLDEFRLKVLDEIKRADYLVSSTWY----GILVQWLKNPRCLKGMKPRKV 269
++ + + L F+ ++ + A + W+ I Q K + G K+
Sbjct: 293 KEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKL 352
Query: 270 NDFVKCATKMISMQIQELMRQSINAIIDFL-KDPEAI-----PVLNVCLDFDGEFI-YDP 322
F CA ++++Q+Q+L S+ D + + P+++ P + L D + I ++P
Sbjct: 353 ESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEP 412
Query: 323 TLETIYEVFHNIADAISHISQRLMPIEQYLKIPYNYDALPVVYNEWLHKDGHERLQQQLN 382
L ++F N+ D + + +E L + + P + + + ++++
Sbjct: 413 ELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSKWESKSKPTTLKPIILNEIVDAHKEKIK 472
Query: 383 -IVFKPLNQYVEKLR--QEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDSNI- 438
++ K E LR +Y+ L A+ ++ F+ E ++E++ ++I YQ + I
Sbjct: 473 EVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAENHSYEKIIDEICKYQKLIEEIQ 532
Query: 439 -TAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAAK 497
T++ + C+ ++ L RA ++A + + H N +C EFE IA K
Sbjct: 533 YTSIKTIRLGMFEMHCE-ELIRALVKRADIICGKLLAKMFRDHQEVNTRLCDEFERIAEK 591
Query: 498 ALKEPENATELIEQGVYILHAKTVLVEALKERILVQINIISNLLEMTSLSSDHVKSNTRT 557
AL P N EL+E YI + + L++R++ N ++ L+E + S ++ N
Sbjct: 592 ALSTPPNTAELMEMKAYIQKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSV 651
Query: 558 VNWLKDIKPIFEKNAAAYETFKADMEESLLGKIAYLNKEVTDMTPYLELLDNMDDVNHTL 617
W + IFE++ + +E L + +E+ E + D+
Sbjct: 652 FQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQ 711
Query: 618 EYLEYLRKLVHRLHDCDKLVTWINNEETTFKFPVTNYPELEELKEFIIPFYSLVYLVHRW 677
YL+ + L +L + N EE F + + YP+ +++++ + P+ L +
Sbjct: 712 RYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEF 771
Query: 678 KRSYYTWMDGPFEYLDHNQIEQDHDFYYKEFLKISKNYRNKIKQQIAEGVEKRFQGLVDD 737
+Y W +GP+ ++ +Q+E D Y++ K+ K + +
Sbjct: 772 SSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDS------------------- 812
Query: 738 PDVNNLPAPMKLCAQAVAEIKDWRPNVQMAHIMCNPALVQRHWDEMSTIAGFDLTPTAGT 797
P + + + ++++D++ ++ + ++CNP L RHW+ MS I G+ L P+ +
Sbjct: 813 ------PYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS 866
Query: 798 SLRKIINFNLWGDLDQYEIISVAATKELALITNLNKMMAEW------------------- 838
++ ++ NL +D++E IS AA+KE +L + KM+ EW
Sbjct: 867 TVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILA 926
Query: 839 ----IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQWLYLL 894
IQ +LDDHI+KT MRGS F+KP+E Q+R W K++ + +DEW KVQ+ WLYL
Sbjct: 927 SVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLE 986
Query: 895 PIFSSKDIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAATAFLE 954
PIFSS DI++QMPEEG F V+ +R M SV +D HVL + +LE + + LE
Sbjct: 987 PIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE 1046
Query: 955 KINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLVFDGE 1014
I G+N YLEKKRL+FPRFFFLSNDE+LEILSETK+P +VQPHLKKCFEGI ++ F
Sbjct: 1047 LILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTET 1106
Query: 1015 FNISAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSETEISYYDYPNMGR 1074
+I+ M S EGE VE +++IS A ARG VEKWLV++E M+ ++ T + + Y R
Sbjct: 1107 LDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYER 1166
Query: 1075 VEWVLSWEGMVVLAISQIYWAVDVHESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLT 1134
+ WV W G VL +SQI+W +V ++ + L+ + +Q+++ V ++ R L+
Sbjct: 1167 INWVRDWPGQTVLCVSQIFWTKEVQTAI-PMGIKALEQYLKTCNRQIDDIVTLV-RGKLS 1224
Query: 1135 KLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWE 1180
+ +T+ AL+V+DVHA+DV+S L+KK +++ +DF+WL+QLRYYW+
Sbjct: 1225 MQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYWQ 1270
>AK097746-1|BAC05158.1| 679|Homo sapiens protein ( Homo sapiens cDNA
FLJ40427 fis, clone TESTI2039113. ).
Length = 679
Score = 471 bits (1161), Expect = e-131
Identities = 215/407 (52%), Positives = 292/407 (71%), Gaps = 2/407 (0%)
Query: 3391 MFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELG 3450
+F+N+Y+ I + AI YLTGECNYGGRVTDDWDRRL++T+L ++ N +V +P+Y F G
Sbjct: 274 LFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNLYIVENPHYKFSPSG 333
Query: 3451 QQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXX 3510
Y P + Y+DY++ I+ +P PE+FGLH N I++D + L SL+L
Sbjct: 334 N-YFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSK 392
Query: 3511 XXXXXXXXX-ILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLN 3569
IL+ + +IL+KLP FD+E+A +KYPV Y ESMNTVL+QEMERFN L+
Sbjct: 393 QTGASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLII 452
Query: 3570 EIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIER 3629
I+++L+DL+KA+KG++VM AL+ S+++L+GK+PE W K SYPSLKPL SY+ DF+ R
Sbjct: 453 TIRNTLRDLEKAIKGVVVMDSALEALSSSLLVGKVPEIWAKRSYPSLKPLGSYITDFLAR 512
Query: 3630 LSMLEDWYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVDYETT 3689
L+ L+DWY +GKP FWL GFFFTQAFLTG++QNYAR T PIDLL ++FE+ D T
Sbjct: 513 LNFLQDWYNSGKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPIDLLGYEFEVIPSDTSDT 572
Query: 3690 PPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPL 3749
P+ GV++ GL++DG RW+RE+ +AEQ PK+L D MP+IW+ P K+ + Y CPL
Sbjct: 573 SPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPL 632
Query: 3750 YKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQLDN 3796
YKT ERKG L+TTGHS+NFV+A L +D+P+ HWIKR VALL QLD+
Sbjct: 633 YKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALLCQLDD 679
Score = 338 bits (830), Expect = 3e-91
Identities = 147/274 (53%), Positives = 203/274 (74%), Gaps = 2/274 (0%)
Query: 3075 FLITGGIAVENHLKKP-VEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIE 3133
FL+TGG+++++ K P WL DK+W+EICR ++ AFR R F + I +W+E+YD E
Sbjct: 2 FLLTGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKE 61
Query: 3134 PQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFG 3193
P N P D+ L + QK++++R LRPDK+T A++ ++ ++G+K+ PPPFD++KS+
Sbjct: 62 PHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYL 121
Query: 3194 DSNCLAPLIFILSPGSDPMGALIKYCERMGFS-HRFNSISLGQGQGPIARAMIEKAQSEG 3252
DSNC PLIF+LSPG+DPM +L+K+ S ++F +ISLGQGQGPIA MI+ A EG
Sbjct: 122 DSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAIEEG 181
Query: 3253 GWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNE 3312
WVCLQNCHLAVSW+P+LEKI E F + SFRLWLTSYPS KFP ++LQ GVKMTNE
Sbjct: 182 TWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKMTNE 241
Query: 3313 PPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTF 3346
PPTGL+ NL +SY+++P+ +PEF++GC GK+ F
Sbjct: 242 PPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELLF 275
>AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens cDNA
FLJ16607 fis, clone TESTI4010382, highly similar to
Rattus norvegicus dynein, cytoplasmic, heavy chain 2
(Dnch2). ).
Length = 1300
Score = 449 bits (1106), Expect = e-124
Identities = 334/1277 (26%), Positives = 591/1277 (46%), Gaps = 50/1277 (3%)
Query: 2507 WGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNK-DFKPHIVAKASAAAEGLC 2565
W K L G + + FD NI + + + NK F P +AS AA L
Sbjct: 24 WVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLA 83
Query: 2566 KWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXXXXXXXXXXXXX 2625
W+ A Y +T + + ++
Sbjct: 84 AWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQS 143
Query: 2626 XNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDNLAGDILVSCGI 2685
+ LE EV + + AE LI L E RW + L ++
Sbjct: 144 RTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAF 203
Query: 2686 IAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNWCIAGLPRDLFS 2745
I YL+ +R +++W E+F + L T+ + W GLP D S
Sbjct: 204 ITYLSAAPESLRKTCLEEWT------KSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLS 257
Query: 2746 IDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKVIETCLEYGKPA 2805
I+NA++ S LIDP QA +W+KT K + L+V+ D N++ +E + +GK
Sbjct: 258 IENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTL 317
Query: 2806 LIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYMTTKLRNPHYLPEI 2865
+I ++ VE L P+L + QG + + +GD +I+Y+ FRL+++T+ NP P+
Sbjct: 318 IIQ-EMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDA 376
Query: 2866 FNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRT 2925
+ VT +NF T+ GL Q L + + E+PDL+E++ KL+ Q + L ++E+ +L T
Sbjct: 377 ASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLET 436
Query: 2926 LQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLY 2985
L ++G+ILE++ IE L+ +K + I + + S + + +++ R Y P+A ++ +Y
Sbjct: 437 LATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMY 496
Query: 2986 YCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSL 3045
+ +++L ++ MY++SL F+ L+ +++N S++ E+R++ L + + +Y +CR L
Sbjct: 497 FIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCL 556
Query: 3046 FDKDKLMFSFIMCSKMMLSTEKMNV-DEYKFLITGGIAVENHLKKPV-EWLPDKAWDEIC 3103
F D+LMF+ M + N D + ++ G + + ++ + + LP +W +
Sbjct: 557 FKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLP--SWIDQE 614
Query: 3104 RLNDLKAFRAFRDDFVKTII-----KWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRV 3158
R + + +T+ W+ Y++ + + P ++++ FQ++LVV+
Sbjct: 615 RSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVVQA 673
Query: 3159 LRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKY 3218
LRPD+L A++ F K +G K +P P ++ + + ++ + P++ I+SPG+DP L +
Sbjct: 674 LRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQEL 733
Query: 3219 CERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFD 3278
++ +++GQGQ +A M+++ G W+CL+N HL VSWLPVLEK +
Sbjct: 734 ANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQ 793
Query: 3279 LTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEG 3338
+T FRLWLT+ F +LQ +K+T E P GL+ NL R+Y E E
Sbjct: 794 PKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY------ESWTPEQ 844
Query: 3339 CPGKDKTF-SKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYE 3397
KD T + L+ +++FHA QER+ + P GW Y F+ SD + + + +
Sbjct: 845 ISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAK 904
Query: 3398 EIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQY--GL 3455
++Q+ + L YGGR+ + +D R++ + L + NS V++ N + Y L
Sbjct: 905 DVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSL 964
Query: 3456 PRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXX 3515
P+ C DY IE +P + P FGL N + IS ++ S L +
Sbjct: 965 PQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQL-RILGRSITAGSK 1023
Query: 3516 XXXXILVLMASEILS---KLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFN--KLLNE 3570
I S +L+ KL ++ I QK P + + + +E+FN +L+
Sbjct: 1024 FDREIWSNELSPVLNLWKKLNQNSNL-IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQS 1082
Query: 3571 IKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWR-KFSYPSLKPLPSYVADFIER 3629
+ SL L K ++G ++S + ++A+L K P W+ K+ P PL Y+ + R
Sbjct: 1083 VHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPE-DPL-QYLRGLVAR 1140
Query: 3630 LSMLEDWYQNGK-----PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIR 3682
+++W + T L F FL Q ARA +D L F ++ R
Sbjct: 1141 ALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGR 1200
Query: 3683 NVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEG 3742
+ + G+ ++G DG + + E + + VL M W+ ++
Sbjct: 1201 LQEAKLQIKISGLLLEGCSFDGNQLS-ENQLDSPSVSSVLPCFMG--WIPQDACGPYSPD 1257
Query: 3743 TRYKCPLYKTLERKGVL 3759
P+Y + ER V+
Sbjct: 1258 ECISLPVYTSAERDRVV 1274
>BC128421-1|AAI28422.1| 798|Homo sapiens DNAH9 protein protein.
Length = 798
Score = 435 bits (1072), Expect = e-120
Identities = 257/821 (31%), Positives = 425/821 (51%), Gaps = 37/821 (4%)
Query: 2988 VTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFD 3047
+ +L + PMYQ+SL F ++ ++E A + L +R+ L D+ T+++Y R LF+
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3048 KDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLND 3107
DKL + + +++L ++N E FL+ V+ PVE+L +AW + L+
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRS--PVQTGTASPVEFLSHQAWGAVKVLSS 118
Query: 3108 LKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIA 3167
++ F D + W++ + P+ + LP W + T Q+L ++R +RPD++T A
Sbjct: 119 MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYA 177
Query: 3168 VSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFS-- 3225
+ F+E+++G KY D + SF +S P+ FILSPG DP+ + ++G++
Sbjct: 178 LRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFN 237
Query: 3226 -HRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDL 3284
F+++SLGQGQ +A A ++ A +G WV LQN HL WL LEK +E N+
Sbjct: 238 NQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHP 296
Query: 3285 SFRLWLTSYPSDK-----FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGC 3339
FR+++++ P+ PQ +L+ +K+TNEPPTG+ NL+++ + + E C
Sbjct: 297 EFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFT---QDTLEMC 353
Query: 3340 PGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEI 3399
++ F +L+ + +FHAVV ER+KFGP GWN Y FN D ISV L FL ++
Sbjct: 354 -SRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412
Query: 3400 QYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRC 3459
Y ++YL GE YGG +TDDWDRRL T L ++ ++ L + LP
Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGE----LSLAPGFPLPGNM 468
Query: 3460 EYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXX 3516
+Y Y ++I++ P ++GLH NA I S +L +++ +
Sbjct: 469 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGAT 528
Query: 3517 XXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQ 3576
+ + EIL ++ +F++ K V+ V QE R N L EI+ SL+
Sbjct: 529 REEKVKALLEEILERVTDEFNIPELMAK--VEERTPYIVVAFQECGRMNILTREIQRSLR 586
Query: 3577 DLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDW 3636
+L+ +KG + M+ ++ NA+ +PE+W + +YPS L ++ D + R+ LE W
Sbjct: 587 ELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAW 646
Query: 3637 YQN-GKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIRNVDYETTPPKW 3693
+ P T WL GFF Q+FLT +Q+ AR P+D + D +N + +PP+
Sbjct: 647 TGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPRE 706
Query: 3694 GVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTL 3753
G ++ GLFM+G W+ + I E K L MPV+++ ++ + + Y CP+YKT
Sbjct: 707 GAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTS 766
Query: 3754 ERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
+R +V F L + + + W+ VALLLQ+
Sbjct: 767 QR---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 798
>BC128261-1|AAI28262.1| 798|Homo sapiens DNAH9 protein protein.
Length = 798
Score = 435 bits (1072), Expect = e-120
Identities = 257/821 (31%), Positives = 425/821 (51%), Gaps = 37/821 (4%)
Query: 2988 VTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFD 3047
+ +L + PMYQ+SL F ++ ++E A + L +R+ L D+ T+++Y R LF+
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3048 KDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLND 3107
DKL + + +++L ++N E FL+ V+ PVE+L +AW + L+
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRS--PVQTGTASPVEFLSHQAWGAVKVLSS 118
Query: 3108 LKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIA 3167
++ F D + W++ + P+ + LP W + T Q+L ++R +RPD++T A
Sbjct: 119 MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYA 177
Query: 3168 VSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFS-- 3225
+ F+E+++G KY D + SF +S P+ FILSPG DP+ + ++G++
Sbjct: 178 LRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFN 237
Query: 3226 -HRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDL 3284
F+++SLGQGQ +A A ++ A +G WV LQN HL WL LEK +E N+
Sbjct: 238 NQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHP 296
Query: 3285 SFRLWLTSYPSDK-----FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGC 3339
FR+++++ P+ PQ +L+ +K+TNEPPTG+ NL+++ + + E C
Sbjct: 297 EFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFT---QDTLEMC 353
Query: 3340 PGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEI 3399
++ F +L+ + +FHAVV ER+KFGP GWN Y FN D ISV L FL ++
Sbjct: 354 -SRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412
Query: 3400 QYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRC 3459
Y ++YL GE YGG +TDDWDRRL T L ++ ++ L + LP
Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGE----LSLAPGFPLPGNM 468
Query: 3460 EYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXX 3516
+Y Y ++I++ P ++GLH NA I S +L +++ +
Sbjct: 469 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGAT 528
Query: 3517 XXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQ 3576
+ + EIL ++ +F++ K V+ V QE R N L EI+ SL+
Sbjct: 529 REEKVKALLEEILERVTDEFNIPELMAK--VEERTPYIVVAFQECGRMNILTREIQRSLR 586
Query: 3577 DLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDW 3636
+L+ +KG + M+ ++ NA+ +PE+W + +YPS L ++ D + R+ LE W
Sbjct: 587 ELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAW 646
Query: 3637 YQN-GKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIRNVDYETTPPKW 3693
+ P T WL GFF Q+FLT +Q+ AR P+D + D +N + +PP+
Sbjct: 647 TGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQIALQCDMTKKNREEFRSPPRE 706
Query: 3694 GVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTL 3753
G ++ GLFM+G W+ + I E K L MPV+++ ++ + + Y CP+YKT
Sbjct: 707 GAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTS 766
Query: 3754 ERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
+R +V F L + + + W+ VALLLQ+
Sbjct: 767 QR---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 798
>X99947-1|CAA68207.1| 798|Homo sapiens dynein-related protein
protein.
Length = 798
Score = 433 bits (1067), Expect = e-120
Identities = 257/821 (31%), Positives = 424/821 (51%), Gaps = 37/821 (4%)
Query: 2988 VTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFD 3047
+ +L + PMYQ+SL F ++ ++E A + L +R+ L D+ T+++Y R LF+
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3048 KDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLND 3107
DKL + + +++L ++N E FL+ V+ PVE+L +AW + L+
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRS--PVQTGTASPVEFLSHQAWGAVKVLSS 118
Query: 3108 LKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIA 3167
++ F D + W++ + P+ + LP W + T Q+L ++R +RPD++T A
Sbjct: 119 MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYA 177
Query: 3168 VSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGFS-- 3225
+ F+E+++G KY D + SF +S P+ FILSPG DP+ + ++G++
Sbjct: 178 LRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFN 237
Query: 3226 -HRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDL 3284
F+++SLGQGQ +A A ++ A +G WV LQN HL WL LEK +E N+
Sbjct: 238 NQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHP 296
Query: 3285 SFRLWLTSYPSDK-----FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGC 3339
FR+++++ P+ PQ +L+ +K+TNEPPTG+ NL+++ + + E C
Sbjct: 297 EFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFT---QDTLEMC 353
Query: 3340 PGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEI 3399
++ F +L+ + +FHAVV ER+KFGP GWN Y FN D ISV L FL ++
Sbjct: 354 -SRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKV 412
Query: 3400 QYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRC 3459
Y ++YL GE YGG +TDDWDRRL T L ++ ++ L + LP
Sbjct: 413 PYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGE----LSLAPGFPLPGNM 468
Query: 3460 EYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXX 3516
+Y Y ++I++ P ++GLH NA I S +L +++ +
Sbjct: 469 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGAT 528
Query: 3517 XXXILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQ 3576
+ + EIL ++ +F++ K V+ V QE R N L EI+ SL+
Sbjct: 529 REEKVKALLEEILERVTDEFNIPELMAK--VEERTPYIVVAFQECGRMNILTREIQRSLR 586
Query: 3577 DLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDW 3636
+L+ +KG + M+ ++ NA+ +PE+W + +YPS L + D + R+ LE W
Sbjct: 587 ELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAARFPDLLNRIKELEAW 646
Query: 3637 YQNGK-PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIRNVDYETTPPKW 3693
+ P T WL GFF Q+FLT +Q+ AR P+D + D +N + +PP+
Sbjct: 647 TGDFTIPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPRE 706
Query: 3694 GVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTL 3753
G ++ GLFM+G W+ + I E K L MPV+++ ++ + + Y CP+YKT
Sbjct: 707 GAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTS 766
Query: 3754 ERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
+R +V F L + + + W+ VALLLQ+
Sbjct: 767 QR---------GPTYVWTFNLKTKENPSKWVLAGVALLLQI 798
>AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens cDNA
FLJ38262 fis, clone FCBBF3001594, moderately similar to
Chlamydomonas reinhardtii dhc1 gene for 1-alpha dynein ).
Length = 828
Score = 432 bits (1064), Expect = e-119
Identities = 262/844 (31%), Positives = 427/844 (50%), Gaps = 25/844 (2%)
Query: 2247 SPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVAHHYM-VKVNVPDPVKSSAVIAC 2305
SP+G + RT R +P +VN IDW+ WP AL VA ++ +P + V
Sbjct: 2 SPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHV 61
Query: 2306 KQFHVDARIVSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQ 2365
H S F R Y+T +YLD I +++ L + K + A R GLD+
Sbjct: 62 VLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDK 121
Query: 2366 LGQAADAVAIMQRDLNA-LKPQLIVMAEKSAK---MMQEIEVETAIADKAAAQVREDQKX 2421
L +A I +LN L Q IV+AEKSA +++EI V TA+A++ E
Sbjct: 122 LKEAT----IQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAME 177
Query: 2422 XXXXXXXXXELKKDCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAA 2481
K + E LA +PILE A L L +D+T ++S PP V+ V
Sbjct: 178 IEEQNKVIAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCEC 237
Query: 2482 VCVXXXXXXXXXXXXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRK 2541
+ + W +K ++ D FL SL D D+I + ++ I K
Sbjct: 238 ILIMKGYKELN--------------WKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNI-K 282
Query: 2542 EYLSNKDFKPHIVAKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAI 2601
L + + S A G+ K++ A+ Y T
Sbjct: 283 GLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRE 342
Query: 2602 LEEKKAMVXXXXXXXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRW 2661
LE + + ++K+ L++E ++ +L A+KLI GLG E +RW
Sbjct: 343 LERIQNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRW 402
Query: 2662 TVAAENLQTLYDNLAGDILVSCGIIAYLAPYTLPIRIEIIDK-WRDLVIKLNMPHSEQFV 2720
+ L L GD L+ ++Y +T R E++++ W++ +++ +P S+ F
Sbjct: 403 LNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFR 462
Query: 2721 FKDVLGTDIKIQNWCIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTND 2780
+ +L D++I W GLP D S+ N I+ + R+ L IDPQ QA WIK E+ N+
Sbjct: 463 LESLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNN 522
Query: 2781 LQVLKFTDGNYMKVIETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDN 2840
L+V F D +++K +E ++YG P L V E ++ +D VL K + G++FI LGD
Sbjct: 523 LRVASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDK 582
Query: 2841 VIEYHPNFRLYMTTKLRNPHYLPEIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEK 2900
++Y NFRLY+ TKL NP Y P +F K +IN+ +T GLEDQ L ++VA ER +L+E+
Sbjct: 583 EVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQ 642
Query: 2901 REKLIVQGAANRAALKQVEDDILRTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEAS 2960
RE LI + + N+ LK +ED +LR L + G++L++ + L+ +K+ A ++ +K + +
Sbjct: 643 REHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLA 702
Query: 2961 LETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSK 3020
+T I++ R GYRP A A+L++ ++E+ V+ MYQYSL F+ ++ +S++ +
Sbjct: 703 EKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDS 762
Query: 3021 DLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGG 3080
L KRL+ + DT T+++Y++ C LF++ KL+FSF M K+ + ++ +E F + G
Sbjct: 763 ILMKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGN 822
Query: 3081 IAVE 3084
I++E
Sbjct: 823 ISLE 826
>AK128065-1|BAC87257.1| 821|Homo sapiens protein ( Homo sapiens cDNA
FLJ46185 fis, clone TESTI4004917, moderately similar to
Dynein beta chain, ciliary. ).
Length = 821
Score = 426 bits (1049), Expect = e-118
Identities = 248/790 (31%), Positives = 428/790 (54%), Gaps = 25/790 (3%)
Query: 2870 TLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDILRTLQET 2929
TLINF +T+DGLEDQ L VVAKERPDL++ L + LK++ED +L L
Sbjct: 6 TLINFLVTRDGLEDQLLAAVVAKERPDLEQLEANLTKSQNEFKIVLKELEDSLLARLSAA 65
Query: 2930 KGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVT 2989
G+ L D + +E L+++K+ A +I +K + TE I + R YRP A +++LY+ +
Sbjct: 66 SGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILN 125
Query: 2990 ELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCRSLFDKD 3049
+L ++P+YQ+SL F ++ +I+ + ++++R+ L D TY++Y R LF++D
Sbjct: 126 DLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERD 185
Query: 3050 KLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHLKKPVEWLPDKAWDEICRLNDLK 3109
KL+F + +++ +++N E FL+ + + PV++L + W I L+++
Sbjct: 186 KLIFLAQVTFQVLSMKKELNPVELDFLLR--FPFKAGVVSPVDFLQHQGWGGIKALSEMD 243
Query: 3110 AFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVS 3169
F+ D + +W+++ + P+ + P W + T QKL +VR LRPD++T A+
Sbjct: 244 EFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDRMTYAIK 302
Query: 3170 QFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKYCERMGF---SH 3226
F+E++MG K+ + SKS+ +S+ + FILSPG DP+ + +++GF +
Sbjct: 303 NFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNG 362
Query: 3227 RFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSF 3286
+ +++SLGQGQ +A ++ A +G WV LQN HL WL L+K +E + T + +
Sbjct: 363 KLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYS-TGSHEDY 421
Query: 3287 RLWLTSYPSDK-----FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPG 3341
R+++++ P+ PQ +L+ +K+TNEPPTG+ NL+++ L + E C
Sbjct: 422 RVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKAL---DLFTQDTLEMCT- 477
Query: 3342 KDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQY 3401
K+ F +L+ + +FHAVV ER+KFG GWN Y FN+ D IS+ L +L ++ +
Sbjct: 478 KEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYNYLEANPKVPW 537
Query: 3402 VAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEY 3461
++YL GE YGG +TDDWDRRL T L Y+ + ++ + + L L + +P +Y
Sbjct: 538 DDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEML-EGDVL---LAPGFQIPPNLDY 593
Query: 3462 QDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLV---XXXXXXXXXXXXX 3518
+ Y ++I+ P ++GLH NA I S +L +++ +
Sbjct: 594 KGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSRE 653
Query: 3519 XILVLMASEILSKLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQDL 3578
+ + +IL K+P + +A+ V QE ER N L NE++ SL++L
Sbjct: 654 EKVKAVLDDILEKIPE--TLNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKEL 711
Query: 3579 QKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQ 3638
+KG + ++ ++ S A+ +P+ W +YPS+ L ++ AD + R+ L +
Sbjct: 712 NLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRRLVCPCR 771
Query: 3639 NGKPPTFWLP 3648
N +P LP
Sbjct: 772 NSRPGRQTLP 781
>AK126059-1|BAC86419.1| 933|Homo sapiens protein ( Homo sapiens cDNA
FLJ44071 fis, clone TESTI4037727, moderately similar to
Dynein beta chain, ciliary. ).
Length = 933
Score = 421 bits (1037), Expect = e-116
Identities = 258/849 (30%), Positives = 446/849 (52%), Gaps = 44/849 (5%)
Query: 2962 ETETIIEKFRLGYRP--IASHSAVLYYCVTELPNVDPMYQYSLTWFINLYIISIENANKS 3019
+++T+ ++ + +RP +A L+ C +V +++ ++ +I+ +
Sbjct: 113 QSKTLSQRNKTNWRPPQVAGSGEGLHLCTPPWLSVADPQAFNV-----VFEKAIQRTTPA 167
Query: 3020 KDLEKRLKFLKDTFTYNLYSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITG 3079
++++R+ L D TY++Y R LF++DKL+F + +++ +++N E FL+
Sbjct: 168 NEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLR- 226
Query: 3080 GIAVENHLKKPVEWLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTL 3139
+ + PV++L + W I L+++ F+ D + +W+++ + P+ +
Sbjct: 227 -FPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIF 285
Query: 3140 PGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLA 3199
P W + T QKL +VR LRPD++T A+ F+E++MG K+ + SKS+ +S+
Sbjct: 286 PKEWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPST 344
Query: 3200 PLIFILSPGSDPMGALIKYCERMGFS---HRFNSISLGQGQGPIARAMIEKAQSEGGWVC 3256
+ FILSPG DP+ + +++GF+ + +++SLGQGQ +A ++ A +G WV
Sbjct: 345 SIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVI 404
Query: 3257 LQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDK-----FPQSVLQVGVKMTN 3311
LQN HL WL L+K +E + T + +R+++++ P+ PQ +L+ +K+TN
Sbjct: 405 LQNIHLVARWLGTLDKKLERYS-TGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITN 463
Query: 3312 EPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGW 3371
EPPTG+ NL+++ L + E C K+ F +L+ + +FHAVV ER+KFG GW
Sbjct: 464 EPPTGMHANLHKAL---DLFTQDTLEMCT-KEMEFKCMLFALCYFHAVVAERRKFGAQGW 519
Query: 3372 NIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILD 3431
N Y FN+ D IS+ L +L ++ + ++YL GE YGG +TDDWDRRL T L
Sbjct: 520 NRSYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLA 579
Query: 3432 NYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRD 3491
Y+ + ++ + + L L + +P +Y+ Y ++I+ P ++GLH NA I
Sbjct: 580 EYIRTEML-EGDVL---LAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFL 635
Query: 3492 YSISMELTSSLVLV---XXXXXXXXXXXXXXILVLMASEILSKLPPKFDVEIAQKKYPVD 3548
S +L +++ + + + +IL K+P F+ +A+
Sbjct: 636 TVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFN--MAEIMAKAA 693
Query: 3549 YNESMNTVLIQEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENW 3608
V QE ER N L NE++ SL++L +KG + ++ ++ S A+ +P+ W
Sbjct: 694 EKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTW 753
Query: 3609 RKFSYPSLKPLPSYVADFIERLSMLEDWYQN-GKPPTFWLPGFFFTQAFLTGSVQNYARA 3667
+YPS+ L ++ AD + R+ LE W + P T WL GFF Q+FLT +Q+ AR
Sbjct: 754 VARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARK 813
Query: 3668 KTIPIDLLVFDFEI--RNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDN 3725
P+D + E+ +N + T PP+ G +V GLFM+G RW+ +T IAE K L
Sbjct: 814 NEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPA 873
Query: 3726 MPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIK 3785
MPVI++ + Y+CP+YKT R +V F L + + +A WI
Sbjct: 874 MPVIFIKAIPVDRMETKNIYECPVYKTRIR---------GPTYVWTFNLKTKEKAAKWIL 924
Query: 3786 RSVALLLQL 3794
+VALLLQ+
Sbjct: 925 AAVALLLQV 933
>BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein.
Length = 314
Score = 390 bits (961), Expect = e-107
Identities = 182/291 (62%), Positives = 227/291 (78%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
EQLSSQ+HYDYGMRAVK+VL+AAGNLK +P E+ESVLLLR++ DVNL KFL+ DVPLF+
Sbjct: 18 EQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQ 77
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
GIISDLFPG+ LPKPDYE FL +D + LQP+ F+ K+IQ YEMM+VRHG+M+VG
Sbjct: 78 GIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVG 137
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
+P GK+ KVL+ AL +H NQ + YK++NPKA+TMGQLYG FD +S+EW DG
Sbjct: 138 DPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDG 197
Query: 1521 IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSM 1580
++A FRE AS + RKWI+FDGPVDA+WIENMNTVLDDNKKLCL SGE++ M++ MS+
Sbjct: 198 VLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSL 257
Query: 1581 IFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEE 1631
IFE DL QASPATVSRCGMIYME LG+ P S+++TL +E++E
Sbjct: 258 IFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKE 308
>AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens cDNA
FLJ43808 fis, clone TESTI4001148, weakly similar to
Dynein beta chain, ciliary. ).
Length = 617
Score = 386 bits (951), Expect = e-106
Identities = 239/617 (38%), Positives = 344/617 (55%), Gaps = 69/617 (11%)
Query: 924 MGSVDKDPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEML 983
MG KDP + L + + LEK +N+YL+ KR FPRFFF+S+DE+L
Sbjct: 1 MGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELL 60
Query: 984 EILSETKNPLKVQPHLKKCFEGINRLVFD----GEFNISAMISMEGEQVEFLDMISVAAA 1039
IL + +PL VQ H+ K ++ I L F+ GE +SAMIS EGE +EF ++ A
Sbjct: 61 SILGSS-DPLCVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKIVR---A 116
Query: 1040 RGSVEKWLVQVEEQMLKAVKSETEISYYDY-PNMGRVEWVLSWEGMVVLAISQIYWAVDV 1098
G VE W+ V +M + + T+ + + Y + RV+W+L ++GMVVLA SQ++W +V
Sbjct: 117 EGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEV 176
Query: 1099 HESLNTHKLSELQAFHS---ELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAKDVI 1155
+ + + E QA + ++ +Q++E V I L+K +++IDVHA+D++
Sbjct: 177 EDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMP-LSKNDRKKYNTVLIIDVHARDIV 235
Query: 1156 SDLIKKKVTEVTDFQWLAQLRYYWEEE--RVYVKIINAVVHYAYEYLGNSDRLVITPLTD 1213
I+ + E +F W +QLR+YW+ E + ++ Y YEY+G + RLVITPLTD
Sbjct: 236 DSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTD 295
Query: 1214 RCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFK 1273
R Y TL A ++L GAP GPAGTGKTETTKDLAKAL + CVV NC +G+DY+A+GK F
Sbjct: 296 RIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFS 355
Query: 1274 GLASCGAW--------------------------AVRQHLETFDFEGTTLKLNPACYVCI 1307
GLA CGAW A+ L TF FEG + L+ + I
Sbjct: 356 GLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFI 415
Query: 1308 TMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQ--LSSQNHYDYGMRAVK-TVL--SA 1362
TMNPGYAGR+ELP+++K LFR V ++VPD I + L S+ + A K TVL A
Sbjct: 416 TMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLA 475
Query: 1363 AGNLKRSFPNE-----SESVLLL------------------RSITDVNLPKFLSFDVPLF 1399
L + + + +SVL++ R++ D+NLPKF+ DVPLF
Sbjct: 476 REQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVLEDVPLF 535
Query: 1400 EGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLV 1459
G+ISDLFPG+ P+ Y +F +A V E N + + KV+Q +E M+ RH M+V
Sbjct: 536 LGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVV 595
Query: 1460 GNPFSGKSMTLKVLSEA 1476
G GKS+ + L +A
Sbjct: 596 GPTRGGKSVVINTLCQA 612
>AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1020
Score = 303 bits (745), Expect = 6e-81
Identities = 182/577 (31%), Positives = 297/577 (51%), Gaps = 35/577 (6%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
E LS Q+HYD+G+RA+K+VL AG+LKR N E +L+R++ D N+PK ++ D+P+F
Sbjct: 41 ELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFL 100
Query: 1401 GIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRHGFMLVG 1460
G++ DLFP + +P+ +F LQP E F++KV+Q E++ VRH +VG
Sbjct: 101 GLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVG 160
Query: 1461 NPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPISYEWTDG 1520
N +GKS L+ L+ + ++ + +P + LNPKAVT +L+G + EW DG
Sbjct: 161 NAGTGKSKILRTLNR--TYVNMKQKP-----VWNDLNPKAVTTDELFGFIHHATREWKDG 213
Query: 1521 ---------IVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEV 1571
+ +++ RE A+ KWIV DG +D +WIE++NTV+DDNK L L S E
Sbjct: 214 KIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNER 273
Query: 1572 MAMSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNPIWLEENEE 1631
+A++ M ++FE+ L A+PATVSR G++Y+ LG+ P+ SW++ + N
Sbjct: 274 IALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLT 333
Query: 1632 YIYDMCDWLFDPLVYYVRKFCGQLVTAGEVNLVISTLRLVE-MLMDNAIEGEEDTKYTRT 1690
++D + +R + + E +LV + L+E +L + + +
Sbjct: 334 ILFDK---YVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVYEV 390
Query: 1691 WFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIPAEGMLIDH 1750
+F + A +W GG L D + +++ E V P++G + D+
Sbjct: 391 YF----VFACIWAFGGTLLQDQISDYQADFSRWWQKEMKA--------VKFPSQGTIFDY 438
Query: 1751 FYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYLKPLLLIGP 1810
+ +K K W D + + + L ++ T ET + Y + L + KPL+L+G
Sbjct: 439 YVDHKTKKL-LPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGN 497
Query: 1811 TGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYGPTRGK 1870
G GK+ +V + L + E Y + ++ Q ++ L K+ +NYGP K
Sbjct: 498 AGVGKTVFVGDTLASL--SEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNK 555
Query: 1871 HAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
I FIDDMNMP ++YG L+R + D HWYD
Sbjct: 556 KLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYD 592
Score = 219 bits (536), Expect = 1e-55
Identities = 124/364 (34%), Positives = 198/364 (54%), Gaps = 19/364 (5%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQGCALLRKESADNKKTFIKIWIHEI 1984
I AT + N PT K HYIFNLRD S V QG E I +W+HE
Sbjct: 669 IQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHES 728
Query: 1985 MRVFYDRLVDDQDRAWFFGVLKKSTRDFMKDTFESALETYQDEKGEVNQENIKKMMFGCY 2044
RV+ D+L+D KK F + E+A + ++ G + +++ + C+
Sbjct: 729 ARVYGDKLID-----------KKDCDLFQRRMLETAYKYFE---GIDSHMLLQQPLIYCH 774
Query: 2045 LDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHLSKICRILS 2104
D + + Y + EV I L YN ++ A M +VLF+ A++H+ +I RIL
Sbjct: 775 F-ADRGK-DPHYMPVKDWEVLKTILTETLDNYNELNAA-MHLVLFEDAMQHVCRISRILR 831
Query: 2105 MPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLVLRESGGLN 2164
P G ALLVGVGGSG+QSL+RLA+ + G +VFQ +T+ Y +++ D+ + +G N
Sbjct: 832 TPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKN 891
Query: 2165 KDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQGGNRNLDIS 2224
T FL T++Q+ +ES++ ++ LL SGE+P+L+ ++ +I+ + + S
Sbjct: 892 MPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHA--LGMVDS 949
Query: 2225 PLQILAFFVGRCKAKLHIVLCFSPIGSSFRTRLRLYPSLVNCCTIDWYDSWPEDALEMVA 2284
FF+ R + +L I+LCFSP+G + R R R +P++VNC IDW+ +WP++AL V+
Sbjct: 950 RENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVS 1009
Query: 2285 HHYM 2288
++
Sbjct: 1010 RRFI 1013
>AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain protein.
Length = 514
Score = 294 bits (722), Expect = 3e-78
Identities = 180/470 (38%), Positives = 259/470 (55%), Gaps = 62/470 (13%)
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY TL A + + GAP GPAGTGKTETTKD+ + L VVFNCSD +D++ +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGL 60
Query: 1269 GKFFKGLASCGAWAV--------------------------RQHLETFDF-EGTTLKLNP 1301
G+ FKGLA GAW ++H ++F F +G + +NP
Sbjct: 61 GRIFKGLAQSGAWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNP 120
Query: 1302 ACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMI--EQLSSQNHYDYGMRA---- 1355
+ +TMNPGYAGR ELP+NLK+ FR+VAMMVPD +I +L+S D + A
Sbjct: 121 EFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFF 180
Query: 1356 -------------------VKTVLSAAGNL---KRSFPNESESVLLLRSITDVNLPKFLS 1393
++ +LS L KR+ P ++ES +++R + D+NL K +
Sbjct: 181 TLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLID 240
Query: 1394 FDVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVR 1453
D PLF +I +LFP I L K Y A + E L + +KVIQ + VR
Sbjct: 241 EDEPLFLSLIENLFPNILLDKAGYPELEAAINRQVEKAGLINHPPWKLKVIQQTKTQRVR 300
Query: 1454 HGFMLVGNPFSGKSMTLKVLSEALSLIHERNQPDGCECTYKVLNPKAVTMGQLYGAFDPI 1513
HG M +G +GK+ + L A++ + +P +NPKA+T Q++G D
Sbjct: 301 HGMMTLGPSGAGKTTCIHTLMRAMT---DCGKPH----REMRMNPKAITAPQMFGRLDVA 353
Query: 1514 SYEWTDGIVATMFREFASEDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMA 1573
+ +WTDGI +T++R+ WI+ DGPVDA+WIEN+N+VLDDNK L L +G+ +
Sbjct: 354 TNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIP 413
Query: 1574 MSNVMSMIFEVMDLSQASPATVSRCGMIYMESTSLGFMPFYKSWLNTLNP 1623
M+ +IFE ++ ASPATVSR GM++M S+ L + P + +L +P
Sbjct: 414 MAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSP 463
>AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein.
Length = 582
Score = 286 bits (701), Expect = 1e-75
Identities = 173/598 (28%), Positives = 280/598 (46%), Gaps = 20/598 (3%)
Query: 2258 RLYPSLVNCCTIDWYDSWPEDALEMVAHHYMV-KVNVP--DPVKSSAVIACKQFHVDARI 2314
R+YPS+++ CTIDWY+ WPE+AL +VA+ ++ KVN + +K C Q H +
Sbjct: 1 RVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKD 60
Query: 2315 VSIDFFNHFGRETYITSASYLDLIKSFTTLTNRKQRELRAAKLRYTNGLDQLGQAADAVA 2374
++ +F GR Y T SYL +++F + ++ E++ + R+ GL + +A V
Sbjct: 61 LNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVT 120
Query: 2375 IMQRDLNALKPQLIVMAEKSAKMMQEIEVETAIADKAAAQVREDQKXXXXXXXXXXELKK 2434
MQ +L L PQ+ +++ +M+++ ++ + +K V++D++ + +
Sbjct: 121 EMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQ 180
Query: 2435 DCEADLALALPILEDAIAALNTLKPADITIVKSMKNPPYTVKLVMAAVCVXXXXXXXXXX 2494
+L LP + AI ALN L AD+ ++ PP+ V VM AVC+
Sbjct: 181 KTANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQKKPN--- 237
Query: 2495 XXXXXXXXMFDFWGPSKRILGDMGFLDSLKNFDKDNIPVATMQKIRKEYLSNKDFKPHIV 2554
W +K +L + GFL L N DKD+IP K++K ++ DF PH +
Sbjct: 238 ------------WATAKLLLSETGFLKKLINLDKDSIPDKVFVKLKK-IVTLPDFNPHKI 284
Query: 2555 AKASAAAEGLCKWIIAMDMYDXXXXXXXXXXXXXXXXXXXXXQTMAILEEKKAMVXXXXX 2614
+ S A LC+W+IA++ Y L EK+ +
Sbjct: 285 SLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEE 344
Query: 2615 XXXXXXXXXXXXNIKKKALEDEVQLCIDKLFRAEKLIGGLGGEKVRWTVAAENLQTLYDN 2674
+K+ L + + + A L+ L EK RW + +
Sbjct: 345 HLLFLQAAYKDTVAEKQLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEG 404
Query: 2675 LAGDILVSCGIIAYLAPYTLPIRIEIIDKWRDLVIKLNMPHSEQFVFKDVLGTDIKIQNW 2734
+ GDIL+S I Y T R I++KW I+ + S +F V+ +I W
Sbjct: 405 ILGDILLSAACIVYSGILTPEFRQLIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRW 464
Query: 2735 CIAGLPRDLFSIDNAIIQDNSMRWSLLIDPQGQANKWIKTMEKTNDLQVLKFTDGNYMKV 2794
GLP +S++NAI+ N +W LLIDP QA+KWI+ ME + LQ L D NY K
Sbjct: 465 HNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQAHKWIRQMEGSR-LQKLSIEDSNYTKK 523
Query: 2795 IETCLEYGKPALIDCVLEDVEAPLDPVLLKLTYLQGGKEFIALGDNVIEYHPNFRLYM 2852
IE ++ G L+ +LE + L +L K Y + G FI +GD EY+ NFR+++
Sbjct: 524 IENAMKTGGSVLLQNLLETLAPGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRIHI 581
>AK095579-1|BAC04578.1| 806|Homo sapiens protein ( Homo sapiens cDNA
FLJ38260 fis, clone FCBBF3001377, highly similar to
Rattus norvegicus dnchc2 mRNA for cytoplasmic dynein
heavy ).
Length = 806
Score = 264 bits (647), Expect = 4e-69
Identities = 209/799 (26%), Positives = 377/799 (47%), Gaps = 42/799 (5%)
Query: 2984 LYYCVTELPNVDPMYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLYSNVCR 3043
+Y+ +++L ++ MY++SL F+ L+ +++N S++ E+R++ L + + +Y +CR
Sbjct: 1 MYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICR 60
Query: 3044 SLFDKDKLMFSFIMCSKMMLSTEKMNV-DEYKFLITGGIAVENHLKKPV-EWLPDKAWDE 3101
LF D+LMF+ M + N D + ++ G + + ++ + + LP +W +
Sbjct: 61 CLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLP--SWID 118
Query: 3102 ICRLNDLKAFRAFRDDFVKTII-----KWQEVYDDIEPQNKTLPGGWDERLTQFQKLLVV 3156
R + + +T+ W+ Y++ + + P ++++ FQ++LVV
Sbjct: 119 QERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQE-FPSILAKKVSLFQQILVV 177
Query: 3157 RVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALI 3216
+ LRPD+L A++ F K +G K +P P ++ + + ++ + P++ I+SPG+DP L
Sbjct: 178 QALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ 237
Query: 3217 KYCERMGFSHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEG 3276
+ ++ +++GQGQ +A M+++ G W+CL+N HL VSWLPVLEK +
Sbjct: 238 ELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNT 297
Query: 3277 FDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFY 3336
+T FRLWLT+ F +LQ +K+T E P GL+ NL R+Y E
Sbjct: 298 LQPKDT---FRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTY------ESWTP 348
Query: 3337 EGCPGKDKTF-SKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQ 3395
E KD T + L+ +++FHA QER+ + P GW Y F+ SD + + +
Sbjct: 349 EQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDG 408
Query: 3396 YEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQY-- 3453
+++Q+ + L YGGR+ + +D R++ + L + NS V++ N + Y
Sbjct: 409 AKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSV 468
Query: 3454 GLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXX 3513
LP+ C DY IE +P + P FGL N + IS ++ S L +
Sbjct: 469 SLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQL-RILGRSITAG 527
Query: 3514 XXXXXXILVLMASEILS---KLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFN--KLL 3568
I S +L+ KL ++ I QK P + + + +E+FN +L+
Sbjct: 528 SKFDREIWSNELSPVLNLWKKLNQNSNL-IHQKVPPPNDRQGSPILSFIILEQFNAIRLV 586
Query: 3569 NEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWR-KFSYPSLKPLPSYVADFI 3627
+ SL L K ++G ++S + ++A+L K P W+ K+ P PL Y+ +
Sbjct: 587 QSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPE-DPL-QYLRGLV 644
Query: 3628 ERLSMLEDWYQNGK-----PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFE 3680
R +++W + T L F FL Q ARA +D L F ++
Sbjct: 645 ARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWK 704
Query: 3681 IRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFN 3740
R + + G+ ++G DG + + E + + VL M W+ ++
Sbjct: 705 GRLQEAKLQIKISGLLLEGCSFDGNQLS-ENQLDSPSVSSVLPCFMG--WIPQDACGPYS 761
Query: 3741 EGTRYKCPLYKTLERKGVL 3759
P+Y + ER V+
Sbjct: 762 PDECISLPVYTSAERDRVV 780
>U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heavy
chain protein.
Length = 655
Score = 264 bits (646), Expect = 6e-69
Identities = 154/456 (33%), Positives = 248/456 (54%), Gaps = 15/456 (3%)
Query: 833 KMMAEW--IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWYEKIVRVNATIDEWGKVQSQW 890
K++ +W I + + D+ ++ S + K FE +V W K+ ++ + +Q +W
Sbjct: 200 KLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKW 259
Query: 891 LYLLPIFSSKDIVAQMPEEGVMFVEVNNIYRRYMGSVDKDPHVLEIAGGTGILEAFRAAT 950
+YL PIF +P+E F V+ +R M + KD V + GI +
Sbjct: 260 VYLEPIFGR----GALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTIL 315
Query: 951 AFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPHLKKCFEGINRLV 1010
L++ +N +LE+KR FPRF+F+ +D++LEIL ++ NP +Q HLKK F GIN +
Sbjct: 316 DQLQRCQRSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVC 375
Query: 1011 FDGEF-NISAMISMEGEQVEFLDMISVAAARGSVEKWLVQVEEQMLKAVKSET-EISYYD 1068
FD + +I+AM S+EGE V F + + ++ +VE WL + +M K ++ E
Sbjct: 376 FDEKSKHITAMKSLEGEVVPFKNKVPLS---NNVETWLNDLALEMKKTLEQLLKECVTTG 432
Query: 1069 YPNMGRVEWVLSWEGMVVLAISQIYWAVDVHESLNTHKLSELQA-FHSELTKQLN-ETVA 1126
+ G V+ L ++ LA QI + DV ++ H L +++ ++L + N +T +
Sbjct: 433 RSSQGAVDPSLFPSQILCLA-EQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSS 491
Query: 1127 VIRRTDLTKLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDFQWLAQLRYYWEEERVY- 1185
+ + + +KALI+ +H DV+ L + +V D+ W QLR+Y + +
Sbjct: 492 EDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMKSDHTCC 551
Query: 1186 VKIINAVVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKD 1245
V+++++ Y YEY GN+ +LV TPLTD+CY TL A + L G P GPAGTGKTE+ K
Sbjct: 552 VQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKA 611
Query: 1246 LAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
L L Q +VFNC +G+D K+MG+ F GL CGAW
Sbjct: 612 LGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAW 647
>U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy chain
1 (DHC1) protein.
Length = 897
Score = 263 bits (645), Expect = 7e-69
Identities = 159/492 (32%), Positives = 261/492 (53%), Gaps = 27/492 (5%)
Query: 815 EIISVAATKELALITNLNK--MMAEW--IQSVLDDHIVKTVGMRGSAFVKPFEAQVRTWY 870
+I V T EL L+ NK ++ W + + + +HI M+ S + K FE +W
Sbjct: 336 QIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWE 395
Query: 871 EKIVRVNATIDEWGKVQSQWLYLLPIFS-SKDIVAQMPEEGVMFVEVNNIYRRYMGSVDK 929
+K+ R+ A D W VQ +W+YL IF+ S DI +P E F ++ + M V K
Sbjct: 396 DKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSK 455
Query: 930 DPHVLEIAGGTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSET 989
P V+++ G+ + L KI + YLE++R FPRF+F+ ++++LEI+ +
Sbjct: 456 SPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNS 515
Query: 990 KNPLKVQPHLKKCFEGINRLVFDGEFNISAMISM-EGEQVEFLDMISVAAARGSVEKWLV 1048
KN K+Q H KK F G++ ++ + + ++ IS EGE+V F +S+ + +WL
Sbjct: 516 KNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITE-HPKINEWLT 574
Query: 1049 QVEEQMLKAV-----KSETEISYYDY-----PNMGRVEWVLSWEGMVVLAISQIYWAVDV 1098
VE++M + +S TE+ + PN + W+ ++ +V+ +QI W+ +V
Sbjct: 575 LVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNT-YITWIDKYQAQLVVLSAQIAWSENV 633
Query: 1099 HESLNTHKLSELQAFHSELTKQLNETVAVIRRTDLTK---LSSITVKALIVIDVHAKDVI 1155
+L++ A + + T+ V+ + L + L ++ LI VH +DV
Sbjct: 634 ETALSSMGGGGDAAPSDSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVT 693
Query: 1156 SDLIKKKVTEVTDFQWLAQLRYYWEE------ERVYVKIINAVVHYAYEYLGNSDRLVIT 1209
LIK K+ F+WL+Q+R+Y++ +++ +++ NA +Y +EYLG D+LV T
Sbjct: 694 RSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQT 753
Query: 1210 PLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMG 1269
PLTDRCY T+ A L G+P GPAGTGKTE+ K L L +VFNC + D++A G
Sbjct: 754 PLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQARG 813
Query: 1270 KFFKGLASCGAW 1281
+ F GL GAW
Sbjct: 814 RIFVGLCQVGAW 825
>AC013274-1|AAY14776.1| 213|Homo sapiens unknown protein.
Length = 213
Score = 256 bits (626), Expect = 1e-66
Identities = 121/213 (56%), Positives = 149/213 (69%)
Query: 3584 GLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDWYQNGKPP 3643
GL VMS L+ +++L KIPE W SYPSLKPL SYV DF+ RL L+ WY+ G PP
Sbjct: 1 GLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPP 60
Query: 3644 TFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMD 3703
FWL GFFFTQAFLTG+ QNYAR TIPIDLL FD+E+ PP+ GVF+ GLF+D
Sbjct: 61 VFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFLD 120
Query: 3704 GGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERKGVLATTG 3763
G WNR+ +AE PK+L D +PV+WL P + + + Y PLYKT ER+GVL+TTG
Sbjct: 121 GASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTG 180
Query: 3764 HSSNFVLAFYLPSDKPSAHWIKRSVALLLQLDN 3796
HS+NFV+A LPSD+P HWI R VALL QL++
Sbjct: 181 HSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS 213
>U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heavy
chain protein.
Length = 197
Score = 254 bits (623), Expect = 3e-66
Identities = 123/174 (70%), Positives = 141/174 (81%), Gaps = 2/174 (1%)
Query: 1110 LQAFHSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAKDVISDLIKKKVTEVTDF 1169
L+ ++ EL QLNE V ++R L+K + T+ AL+ IDV A+DV+ D+IK V+ TDF
Sbjct: 16 LKKYYKELQNQLNEIVELVRGK-LSKQTRTTLGALVTIDVRARDVVMDMIKMGVSHDTDF 74
Query: 1170 QWLAQLRYYWEEERVYVKIINA-VVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLN 1228
WLAQLRYYWE E V+II ++ YAYEYLGNS RLVITPLTDRCYRTLIGA+YL+L
Sbjct: 75 LWLAQLRYYWENENARVRIIQLPMLKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLG 134
Query: 1229 GAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWA 1282
GAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDY AMGKFFKGLAS GAWA
Sbjct: 135 GAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWA 188
>AF015265-1|AAC27542.1| 377|Homo sapiens axonemal dynein protein.
Length = 377
Score = 248 bits (606), Expect = 4e-64
Identities = 132/363 (36%), Positives = 203/363 (55%), Gaps = 18/363 (4%)
Query: 3134 PQNKTLPGGWDERLTQFQKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFG 3193
P+ + LP W + T Q+L ++R +RPD++T A+ F+E+++G KY D + SF
Sbjct: 4 PEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFE 62
Query: 3194 DSNCLAPLIFILSPGSDPMGALIKYCERMGFS---HRFNSISLGQGQGPIARAMIEKAQS 3250
+S P+ FILSPG DP+ + ++G++ F+++SLGQGQ +A A ++ A
Sbjct: 63 ESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAK 122
Query: 3251 EGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTSYPSDK-----FPQSVLQV 3305
+G WV LQN HL WL LEK +E N+ FR+++++ P+ PQ +L+
Sbjct: 123 KGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAEPAPSPEGHIIPQGILEN 181
Query: 3306 GVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKK 3365
+K+TNEPPTG+ NL+++ + + E C ++ F +L+ + +FHAVV ER+K
Sbjct: 182 SIKITNEPPTGMHANLHKALDNFT---QDTLEMC-SRETEFKSILFALCYFHAVVAERRK 237
Query: 3366 FGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRL 3425
FGP GWN Y FN D ISV L FL ++ Y ++YL GE YGG +TDDWDRRL
Sbjct: 238 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 297
Query: 3426 IVTILDNYVNSGVVNDPNYLFCELGQQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMN 3485
T L + ++ L + LP +Y Y ++I++ P ++GLH N
Sbjct: 298 CRTYLGEVIRPEMLEGE----LSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPN 353
Query: 3486 AGI 3488
A I
Sbjct: 354 AEI 356
>AK027182-1|BAB15685.1| 366|Homo sapiens protein ( Homo sapiens cDNA:
FLJ23529 fis, clone LNG06042. ).
Length = 366
Score = 228 bits (558), Expect = 3e-58
Identities = 130/360 (36%), Positives = 199/360 (55%), Gaps = 28/360 (7%)
Query: 3462 QDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXIL 3521
Q++ +IE++P+ PE+FG+H NA + Y + L ++++ V +
Sbjct: 6 QEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEI 65
Query: 3522 VL-MASEILSKLPPKFDVEIAQKKYPV-DYN---ESMNTVLIQEMERFNKLLNEIKSSLQ 3576
V + + + +++P K ++E A + V D S+ TVL QE++RFN LL I +SL+
Sbjct: 66 VQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLE 125
Query: 3577 DLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDW 3636
L KA+ G +VMS ++ N+ L ++P W +YPSLKPL S+V D I R S ++ W
Sbjct: 126 TLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVRDLILRTSFVDLW 185
Query: 3637 YQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEI----RN--------- 3683
+ G+P ++W+ GFFF Q FLTG++QN+AR +PID L F + + R+
Sbjct: 186 LKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAK 245
Query: 3684 ---------VDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPK 3734
+D E P+ GV V G+FMD RW+ + I + LP +N +PV+ P+
Sbjct: 246 TVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQ 305
Query: 3735 LKNEFNEGTRYKCPLYKTLERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALLLQL 3794
+N T Y CPLYKT R G L+TTGHS+NFV+ LPS + +WI + LL QL
Sbjct: 306 -QNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSVLLCQL 364
>AK054657-1|BAB70785.1| 333|Homo sapiens protein ( Homo sapiens cDNA
FLJ30095 fis, clone BNGH41000039, moderately similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 333
Score = 224 bits (548), Expect = 4e-57
Identities = 121/338 (35%), Positives = 189/338 (55%), Gaps = 17/338 (5%)
Query: 3159 LRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSDPMGALIKY 3218
+RPD++T A+ F+E+++G KY D+ K+F +S+ P+ FILSPG D + L
Sbjct: 1 MRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEIL 60
Query: 3219 CERMGF---SHRFNSISLGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVE 3275
+R+GF S +F+++SLGQGQ +A +EKA G WV LQN HL WL LEK++E
Sbjct: 61 GKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLE 120
Query: 3276 GFDLTNTDLSFRLWLT--SYPSDK---FPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPL 3330
F + +R++++ S P+ PQ +L+ +K+TNEPPTG+ NL+ + +
Sbjct: 121 RFS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNF-- 177
Query: 3331 KEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQ 3390
+ + E C K++ F + + + +FHA V R +FGP GW+ Y FN D I L
Sbjct: 178 -DQDTLEIC-SKEQEFKSIFFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLY 235
Query: 3391 MFLNQYEEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELG 3450
+L ++ + ++YL GE YGG +TDDWDR+L L+ +VN ++ D L
Sbjct: 236 NYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFVNPSLIEDE----LMLA 291
Query: 3451 QQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNAGI 3488
+ P +Y Y ++IE + P ++GLH NA I
Sbjct: 292 PGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEI 329
>AK026756-1|BAB15543.1| 394|Homo sapiens protein ( Homo sapiens cDNA:
FLJ23103 fis, clone LNG07621. ).
Length = 394
Score = 217 bits (530), Expect = 6e-55
Identities = 129/398 (32%), Positives = 209/398 (52%), Gaps = 19/398 (4%)
Query: 3399 IQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQYGLPRR 3458
+ + I+Y+ GE YGGRVTDD+D+RL+ T + + + P++ F Q Y +P+
Sbjct: 7 VSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFG-PDFSFY---QGYNIPKC 62
Query: 3459 CEYQDYLKHIESVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVX-XXXXXXXXXXX 3517
+YL++I+S+P PEVFGLH NA IT ++ ++ +++ +
Sbjct: 63 STVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETR 122
Query: 3518 XXILVLMASEILSKLPPKF-DVEIAQKKYPVDYNESMNTVLIQEMERFNKLLNEIKSSLQ 3576
++ +A ++L KLPP + E+ ++ + + MN L QE++R ++L+ ++S+L
Sbjct: 123 EAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLT 182
Query: 3577 DLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKPLPSYVADFIERLSMLEDW 3636
+L+ A+ G I+MS L + M +IP W+K S+ L + + IER S W
Sbjct: 183 ELKLAIDGTIIMSENLQDALDCMFDARIPAWWKKASWV-FSTLGFWFTELIERNSQFTSW 241
Query: 3637 YQNGKPPTFWLPGFFFTQAFLTGSVQNYARA-KTIPIDLLVFDFEIRN--VDYETTPPKW 3693
NG+P FW+ GFF Q FLT Q RA K +D +V E+ D +TPP
Sbjct: 242 VFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISTPPTE 301
Query: 3694 GVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTL 3753
GV+V GL+++G W++ + E PKVL + MPVI +Y + N + Y CP+YK
Sbjct: 302 GVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAE-NNTLRDPRFYSCPIYKKP 360
Query: 3754 ERKGVLATTGHSSNFVLAFYLPSDKPSAHWIKRSVALL 3791
R + N++ A L + + HW+ R VALL
Sbjct: 361 VRTDL--------NYIAAVDLRTAQTPEHWVLRGVALL 390
>AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 180 bits (439), Expect = 7e-44
Identities = 95/143 (66%), Positives = 101/143 (70%), Gaps = 26/143 (18%)
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y +EYLGNS RLVITPLTDRCYRTL+GA L+L GAPEGPAGTGKTETTKDLAKALA QC
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQC 60
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAW--------------------------AVRQHLE 1288
VVFNCSDGLDYKAMGKFFKGLA GAW A+ + L+
Sbjct: 61 VVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLK 120
Query: 1289 TFDFEGTTLKLNPACYVCITMNP 1311
TF FEGT L LNP C V ITMNP
Sbjct: 121 TFIFEGTELSLNPTCAVFITMNP 143
>AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 178 bits (434), Expect = 3e-43
Identities = 94/143 (65%), Positives = 100/143 (69%), Gaps = 26/143 (18%)
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y +EYLGNS RLVITPLTDRCYRTL GA +LHL GAPEGPAGTGKTETTKDLAKA+A QC
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 60
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAWA---------------VRQHLETFD-------- 1291
VVFNCSDGLDY A+GKFFKGL SCGAWA V Q + T
Sbjct: 61 VVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGAD 120
Query: 1292 ---FEGTTLKLNPACYVCITMNP 1311
FEGT LKL+P C V ITMNP
Sbjct: 121 ILMFEGTELKLDPTCAVFITMNP 143
>AK021818-1|BAB13905.1| 553|Homo sapiens protein ( Homo sapiens cDNA
FLJ11756 fis, clone HEMBA1005595, weakly similar to
DYNEIN HEAVY CHAIN, CYTOSOLIC. ).
Length = 553
Score = 176 bits (428), Expect = 1e-42
Identities = 150/543 (27%), Positives = 245/543 (45%), Gaps = 32/543 (5%)
Query: 3233 LGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTS 3292
+GQGQ +A M+++ G W+CL+N HL VSWLPVLEK + +T FRLWLT+
Sbjct: 1 MGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDT---FRLWLTA 57
Query: 3293 YPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTF-SKLLY 3351
F +LQ +K+T E P GL+ NL R+Y E E KD T + L+
Sbjct: 58 EVHPNFTPILLQSSLKITYESPPGLKKNLMRTY------ESWTPEQISKKDNTHRAHALF 111
Query: 3352 GISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGEC 3411
+++FHA QER+ + P GW Y F+ SD + + + +++Q+ + L
Sbjct: 112 SLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENA 171
Query: 3412 NYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQY--GLPRRCEYQDYLKHIE 3469
YGGR+ + +D R++ + L + NS V++ N + Y LP+ C DY IE
Sbjct: 172 IYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIE 231
Query: 3470 SVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEIL 3529
+P + P FGL N + IS ++ S L + I S +L
Sbjct: 232 KIPEDDKPSFFGLPANIARSSQRMISSQVISQL-RILGRSITAGSKFDREIWSNELSPVL 290
Query: 3530 S---KLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFN--KLLNEIKSSLQDLQKAVKG 3584
+ KL ++ I QK P + + + +E+FN +L+ + SL L K ++G
Sbjct: 291 NLWKKLNQNSNL-IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRG 349
Query: 3585 LIVMSPALDLQSNAMLLGKIPENWR-KFSYPSLKPLPSYVADFIERLSMLEDWYQNGK-- 3641
++S + ++A+L K P W+ K+ P PL Y+ + R +++W +
Sbjct: 350 TTLLSSEVQKLASALLNQKCPLAWQSKWEGPE-DPL-QYLRGLVARALAIQNWVDKAEKQ 407
Query: 3642 ---PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVF--DFEIRNVDYETTPPKWGVF 3696
T L F FL Q ARA +D L F ++ R + + G+
Sbjct: 408 ALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLL 467
Query: 3697 VQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIWLYPKLKNEFNEGTRYKCPLYKTLERK 3756
++G DG + + E + + VL M W+ + ++ P+Y + ER
Sbjct: 468 LEGCSFDGNQLS-ENQLDSPSVSSVLPCFMG--WIPQDARGPYSPDECISLPVYTSAERD 524
Query: 3757 GVL 3759
V+
Sbjct: 525 RVV 527
>BC037496-1|AAH37496.1| 504|Homo sapiens DYNC2H1 protein protein.
Length = 504
Score = 173 bits (420), Expect = 1e-41
Identities = 139/486 (28%), Positives = 222/486 (45%), Gaps = 30/486 (6%)
Query: 3233 LGQGQGPIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLEKIVEGFDLTNTDLSFRLWLTS 3292
+GQGQ +A M+++ G W+CL+N HL VSWLPVLEK + +T FRLWLT+
Sbjct: 1 MGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDT---FRLWLTA 57
Query: 3293 YPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLKEPEFYEGCPGKDKTF-SKLLY 3351
F +LQ +K+T E P GL+ NL R+Y E E KD T + L+
Sbjct: 58 EVHPNFTPILLQSSLKITYESPPGLKKNLMRTY------ESWTPEQISKKDNTHRAHALF 111
Query: 3352 GISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQMFLNQYEEIQYVAIKYLTGEC 3411
+++FHA QER+ + P GW Y F+ SD + + + +++Q+ + L
Sbjct: 112 SLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENA 171
Query: 3412 NYGGRVTDDWDRRLIVTILDNYVNSGVVNDPNYLFCELGQQY--GLPRRCEYQDYLKHIE 3469
YGGR+ + +D R++ + L + NS V++ N + Y LP+ C DY IE
Sbjct: 172 IYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIE 231
Query: 3470 SVPINPPPEVFGLHMNAGITRDYSISMELTSSLVLVXXXXXXXXXXXXXXILVLMASEIL 3529
+P + P FGL N + IS ++ S L + I S +L
Sbjct: 232 KIPEDDKPSFFGLPANIARSSQRMISSQVISQL-RILGRSITAGSKFDREIWSNELSPVL 290
Query: 3530 S---KLPPKFDVEIAQKKYPVDYNESMNTVLIQEMERFN--KLLNEIKSSLQDLQKAVKG 3584
+ KL ++ I QK P + + + +E+FN +L+ + SL L K ++G
Sbjct: 291 NLWKKLNQNSNL-IHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRG 349
Query: 3585 LIVMSPALDLQSNAMLLGKIPENWR-KFSYPSLKPLPSYVADFIERLSMLEDWYQNGK-- 3641
++S + ++A+L K P W+ K+ P PL Y+ + R +++W +
Sbjct: 350 TTLLSSEVQKLASALLNQKCPLAWQSKWEGPE-DPL-QYLRGLVARALAIQNWVDKAEKQ 407
Query: 3642 ---PPTFWLPGFFFTQAFLTGSVQNYARAKTIPIDLLVFDFEIRNVDYETTPPKWGVFVQ 3698
T L F FL Q ARA +D L F + + K + +
Sbjct: 408 ALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF---VASWKGRLQEAKLQIKIS 464
Query: 3699 GLFMDG 3704
GL ++G
Sbjct: 465 GLLLEG 470
>Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy chain
protein.
Length = 177
Score = 171 bits (415), Expect = 6e-41
Identities = 91/138 (65%), Positives = 98/138 (71%), Gaps = 26/138 (18%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW----------- 1281
GPAGTGKTETTK LAKALA QCVVFNCSDGLDYKAMGKFFKGLA GAW
Sbjct: 1 GPAGTGKTETTKVLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEV 60
Query: 1282 ---------------AVRQHLETFDFEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVL 1326
A+ + L+TF FEGT L LNP C V ITMNPGYAGR+ELPDNLK L
Sbjct: 61 EVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPDNLKAL 120
Query: 1327 FRTVAMMVPDYAMIEQLS 1344
FRTVAMMVPDYA+I ++S
Sbjct: 121 FRTVAMMVPDYALIGEIS 138
>Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 179
Score = 167 bits (406), Expect = 7e-40
Identities = 96/148 (64%), Positives = 103/148 (69%), Gaps = 31/148 (20%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW----------- 1281
GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDY AMGKFFKGLAS GAW
Sbjct: 1 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 60
Query: 1282 ---------------AVRQHLETFDF-EGTTLKLNPA-CYVCITMNPGYAGRSELPDNLK 1324
A++Q L F F EGT LKLNP +V ITMNPGYAG SELPDNLK
Sbjct: 61 EVLSVVAQQILCIQRAIQQKLVVFWFLEGTELKLNPGIVFVAITMNPGYAGHSELPDNLK 120
Query: 1325 VLFRTVAMMVPDYAMIEQLSSQNHYDYG 1352
VLFRTVAMMVP+YA+I ++S Y YG
Sbjct: 121 VLFRTVAMMVPNYALIAEISL---YSYG 145
>BC021297-1|AAH21297.1| 832|Homo sapiens DYNC1H1 protein protein.
Length = 832
Score = 159 bits (385), Expect = 2e-37
Identities = 133/526 (25%), Positives = 247/526 (46%), Gaps = 46/526 (8%)
Query: 2991 LPNVDPMYQYSLTWFINLYI-ISIENANKS--KDLEKRLKFL-KDTFTYNLYSNVCRSLF 3046
L + +YQYSL +F+++Y + EN N D +RL + KD F ++ V R +
Sbjct: 4 LKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQV-AFNRVARGML 62
Query: 3047 DKDKLMFSFIMCSKMMLST--EKMNVDEYKFLITGGIAVENHLKKP-VEWLPDKAWDEIC 3103
+D + F+ ++ + T E E++ + G V + P ++ L + + +
Sbjct: 63 HQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVV 122
Query: 3104 RLNDLKAFRAFRDDFVKTIIKWQE--VYDDIEPQNKTLPGGWDERLTQ------FQKLLV 3155
RL+ L AF+ D + + ++ ++ D +T+P W E +LL+
Sbjct: 123 RLSCLPAFK----DLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLL 178
Query: 3156 VRVLRPDKLTIAVSQFLEKEMGRKYTT--PPPFDISKSFG-DSNCLAPLIFILSPGSDPM 3212
++ RPD+L F+ +G + + P D++ G + P++ PG D
Sbjct: 179 IQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDAS 238
Query: 3213 GALIKYCERMGFSHRFNSISLGQGQG-PIARAMIEKAQSEGGWVCLQNCHLAVSWLPVLE 3271
G + + + SI++G +G A I A G WV L+N HLA WL LE
Sbjct: 239 GHVEDLAAEQ--NTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLE 296
Query: 3272 KIVEGFDLTNTDLSFRLWLTSYPSDKFPQSVLQVGVKMTNEPPTGLQHNLNRSYISEPLK 3331
K + FRL+LT + K P ++L+ G EPP G++ N+ R++ S P+
Sbjct: 297 KKLHSLQ---PHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVS 353
Query: 3332 EPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDFQISVMQLQM 3391
C ++ ++L + +++FHA++QER ++ PLGW+ +Y F +SD + + +
Sbjct: 354 RI-----CKSPNER-ARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDT 407
Query: 3392 FLNQY---------EEIQYVAIKYLTGECNYGGRVTDDWDRRLIVTILDNYVNSGVVNDP 3442
+L+ ++I + A+K L + YGGRV +++D+RL+ T L+ + +
Sbjct: 408 WLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSE 467
Query: 3443 NYLFCELG--QQYGLPRRCEYQDYLKHIESVPINPPPEVFGLHMNA 3486
L C++ + +P +++++ +E +P P GL NA
Sbjct: 468 FKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNA 513
Score = 45.2 bits (102), Expect = 0.005
Identities = 44/212 (20%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 3559 QEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKP 3618
+E++ KLL +++ L D+ + +G + L N ++ G +P +W ++ P+
Sbjct: 601 REVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMT 660
Query: 3619 LPSYVADFIERLSMLED--------WYQNGKPPTFWLPGFFFTQAFLTGSVQNYARAKTI 3670
+ +V+DF ER+ L++ + K L G F +A++T + Q A+A +
Sbjct: 661 VIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSW 720
Query: 3671 PIDLLVFDFEIRNVDYETTPPKWGVFVQGLFMDGGRWNRETHAIAEQLPKVLNDNMPVIW 3730
++ L + + T V GL + G N +++ + L P+
Sbjct: 721 SLEELCLEVNV-TTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTAL----PLTQ 775
Query: 3731 L-YPKLKNEFNEGTRYKCPLYKTLERKGVLAT 3761
L + K N + + P+Y R ++ T
Sbjct: 776 LRWVKQTNTEKKASVVTLPVYLNFTRADLIFT 807
>AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 158 bits (383), Expect = 4e-37
Identities = 85/143 (59%), Positives = 93/143 (65%), Gaps = 26/143 (18%)
Query: 1195 YAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQC 1254
Y +EYLGNS RLVITPLTDRCY TL GA +L GAP GPAGTGKTETTKDL KALA+Q
Sbjct: 1 YGFEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQT 60
Query: 1255 VVFNCSDGLDYKAMGKFFKGLASCGAWAV--------------------------RQHLE 1288
VVFNCSD LD+ AMGKFFKGLAS GAWA +Q +E
Sbjct: 61 VVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVE 120
Query: 1289 TFDFEGTTLKLNPACYVCITMNP 1311
F FEG + L P+C V ITMNP
Sbjct: 121 RFMFEGVEIPLVPSCAVFITMNP 143
>Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy chain
protein.
Length = 169
Score = 154 bits (374), Expect = 5e-36
Identities = 84/132 (63%), Positives = 91/132 (68%), Gaps = 26/132 (19%)
Query: 1238 GKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWA--------------- 1282
GKTETTKDLAKA+A QCVVF+C DGLDY A+GKFFKGL SCGAWA
Sbjct: 1 GKTETTKDLAKAVAKQCVVFDCPDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSV 60
Query: 1283 VRQHLETFD-----------FEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVA 1331
V Q + T FEGT LKL+P C V ITMNPGYAGRSELPDNLK LFRTVA
Sbjct: 61 VAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGRSELPDNLKALFRTVA 120
Query: 1332 MMVPDYAMIEQL 1343
MMVPDYAMI ++
Sbjct: 121 MMVPDYAMIAEI 132
>BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein.
Length = 551
Score = 148 bits (359), Expect = 3e-34
Identities = 67/179 (37%), Positives = 120/179 (67%)
Query: 2037 KKMMFGCYLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHL 2096
K ++FG ++ + + +R Y+++P E N+ L +YN + ++ +V F A+EH+
Sbjct: 342 KPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHV 401
Query: 2097 SKICRILSMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLV 2156
S+I R++ GNALLVGVGG+G+QSLTRLA+ I G + Q E+++ Y+ +H+D++ +
Sbjct: 402 SRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKL 461
Query: 2157 LRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQ 2215
+ +G +K+ FLFT++QI E ++++++++LNSGEVPNL+ DE +++L R A+
Sbjct: 462 YKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAK 520
Score = 103 bits (246), Expect = 2e-20
Identities = 64/225 (28%), Positives = 102/225 (45%), Gaps = 11/225 (4%)
Query: 1683 EDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIP 1742
E TK T + + +W LGG L + + FD ++ F + D +P
Sbjct: 2 EQTKLN-TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD---------DNPDARLP 51
Query: 1743 AEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
G L + K W + + + + ++PT +T ++ YL+
Sbjct: 52 NSGDLWSIHMDFDTKRL-DPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVK 110
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
+L G TG GKS + L + Y P ++ S+ +TQ+++ SKL ++RKN
Sbjct: 111 HSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKN 170
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
G K +IF+DD+NMP + YG+QP IELLR Y D +YD
Sbjct: 171 ILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYD 215
Score = 48.8 bits (111), Expect = 4e-04
Identities = 19/36 (52%), Positives = 28/36 (77%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQ 1960
+ A+ +IY++ +L PTPAKSHY+FNLRD S+ +Q
Sbjct: 291 VEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQ 326
>AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein.
Length = 224
Score = 148 bits (359), Expect = 3e-34
Identities = 67/179 (37%), Positives = 120/179 (67%)
Query: 2037 KKMMFGCYLDTDSAEGERRYEEIPSKEVFLNIAVSMLSEYNSMHKAKMTIVLFDYALEHL 2096
K ++FG ++ + + +R Y+++P E N+ L +YN + ++ +V F A+EH+
Sbjct: 15 KPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHV 74
Query: 2097 SKICRILSMPSGNALLVGVGGSGRQSLTRLASTILGQQVFQPEITKSYSVKDWHDDIKLV 2156
S+I R++ GNALLVGVGG+G+QSLTRLA+ I G + Q E+++ Y+ +H+D++ +
Sbjct: 75 SRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKL 134
Query: 2157 LRESGGLNKDTTFLFTESQIKEESYIQNLDSLLNSGEVPNLYGLDEKQEILELVRLAAQ 2215
+ +G +K+ FLFT++QI E ++++++++LNSGEVPNL+ DE +++L R A+
Sbjct: 135 YKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAK 193
>U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein.
Length = 80
Score = 132 bits (318), Expect = 3e-29
Identities = 59/73 (80%), Positives = 62/73 (84%)
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY L+GA L L GAP GPAGTGKTETTKDLAKALA+QCVVFNCSDGLDYK M
Sbjct: 1 TPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMM 60
Query: 1269 GKFFKGLASCGAW 1281
G+FF GLA GAW
Sbjct: 61 GRFFSGLAQSGAW 73
>AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 134
Score = 123 bits (296), Expect = 1e-26
Identities = 63/137 (45%), Positives = 88/137 (64%), Gaps = 9/137 (6%)
Query: 1282 AVRQHLETFDF-EGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMI 1340
A ++ + F F +G + LNP + +TMNPGYAGR ELP+NLK+ FRTVAMMVPD
Sbjct: 2 ARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPD---- 57
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
Q HYD+G+R + +VL G+ KR+ P +SE +++R + D+NL K + D PLF
Sbjct: 58 ----RQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFL 113
Query: 1401 GIISDLFPGISLPKPDY 1417
+I+DLFPG+ L Y
Sbjct: 114 SLINDLFPGLQLDSNTY 130
>AK126276-1|BAC86512.1| 457|Homo sapiens protein ( Homo sapiens
cDNA FLJ44290 fis, clone TRACH2019473. ).
Length = 457
Score = 120 bits (288), Expect = 1e-25
Identities = 98/434 (22%), Positives = 197/434 (45%), Gaps = 27/434 (6%)
Query: 17 RVPVMPPVPDIHMMDKLPFTPLPPYNRIKDKQAKFRKILEEKATK---RKVEIARPLLEL 73
++P + +P+ D + L Y R K++Q K +++ + A + R + PLL
Sbjct: 19 KLPPIVHLPENIGADTPTQSKLLKYRRSKEQQQKINQLVIDGAKRNLDRTLGKRTPLLPP 78
Query: 74 YERDRLVESQSKHIGV----LRECAEKIKAPPMLKSWERKIRNLIPANLRQSFPT--LVE 127
+ + + S+ K G +++C E P+ + W + LIP +L++ L+E
Sbjct: 79 PDYPQTMTSEMKKKGFNYIYMKQCVESSPLVPIQQEWLDHMLRLIPESLKEGKEREELLE 138
Query: 128 ELMNESKDEWDRNLHDLAVKTVIRDVPGVPRKRYEEPHFKFKGVTSNYGK-----LLKYR 182
L+NE +++ ++ V++V+ P V E V +Y ++ R
Sbjct: 139 SLINEVSSDFENSMKRYLVQSVLVKPP-VKSLEDEGGPLPESPVGLDYSNPWHSSYVQAR 197
Query: 183 RKLQDGSLLLHPFIRLILESSEKTFP-LHIIDLAKYRAKGPMSLDEFRLKVLDEIKRADY 241
++ ++HP ++++L+ TF ++D RAKGP+ + + + + + A+
Sbjct: 198 NQIFSNLHIIHPTMKMLLDLGYTTFADTVLLDFTGIRAKGPIDCESLKTDLSIQTRNAEE 257
Query: 242 LVSSTWYGILVQWLKNPRCLKGMKPRKVNDFVKCATKMISMQIQELMRQSINAIIDFL-- 299
+ +TWY ++ L+G+KP K++ F C + ++S Q+++L+R+++ +
Sbjct: 258 KIMNTWYPKVINLFTKKEALEGVKPEKLDAFYSCVSTLMSNQLKDLLRRTVEGFVKLFDP 317
Query: 300 KDPEAIPVLNVCLDFDGEFI-YDPTLETIYEVFHNIADAISHISQRLMPIEQYL---KIP 355
KD + +P+ + L FD + + + PT + + + ++ + I+ Q + I +L P
Sbjct: 318 KDQQRLPIFKIELTFDDDKMEFYPTFQDLEDNVLSLVERIAEALQNVQTIPSWLSGTSTP 377
Query: 356 YNYDA-LPVVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKF 414
N D LP W + + L K YVEK YN L A E +E F
Sbjct: 378 VNLDTELPEHVLHWAVDTLKAAVHRNLEGARKHYETYVEK----YNWLLDGTAVENIETF 433
Query: 415 INETEAFEELRNKI 428
E F+E ++
Sbjct: 434 QTEDHTFDEYTEEL 447
>U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy chain
isotype3 protein.
Length = 102
Score = 114 bits (274), Expect = 7e-24
Identities = 64/102 (62%), Positives = 67/102 (65%), Gaps = 26/102 (25%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW----------- 1281
GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDY AMGKFFKGLAS GAW
Sbjct: 1 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIEL 60
Query: 1282 ---------------AVRQHLETFDFEGTTLKLNPACYVCIT 1308
A++Q L F FEGT LKLNP C+V IT
Sbjct: 61 EVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAIT 102
>U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isotype 1B
protein.
Length = 161
Score = 108 bits (260), Expect = 3e-22
Identities = 65/158 (41%), Positives = 83/158 (52%), Gaps = 29/158 (18%)
Query: 1215 CYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKG 1274
CY TL A + L G P GPAGTGKTE+ K L L Q +VFNC +G+D K+MG+ F G
Sbjct: 1 CYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVG 60
Query: 1275 LASCGAW--------------------------AVRQHLETFDFEGTTLKLNPACYVCIT 1308
L CGAW A++ H + G +++N + IT
Sbjct: 61 LVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFIT 120
Query: 1309 MNP---GYAGRSELPDNLKVLFRTVAMMVPDYAMIEQL 1343
MNP GY GR +LPDNLK LFR VAM PD +I ++
Sbjct: 121 MNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEV 158
>U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy chain
isotype3b protein.
Length = 50
Score = 104 bits (250), Expect = 5e-21
Identities = 47/50 (94%), Positives = 47/50 (94%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWA 1282
GPAGTGKTETTKDLAKALA QCVVFNCSDGLDYKAMGKFFKGLA GAWA
Sbjct: 1 GPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWA 50
>U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein.
Length = 79
Score = 104 bits (250), Expect = 5e-21
Identities = 45/73 (61%), Positives = 54/73 (73%)
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY TL A + + GAP GPAGTGKTETTKD+ + L VVFNCSD +D++ +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKDVVVFNCSDQMDFRGL 60
Query: 1269 GKFFKGLASCGAW 1281
G+ FKGLA GAW
Sbjct: 61 GRIFKGLAQSGAW 73
>AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 103 bits (246), Expect = 2e-20
Identities = 64/225 (28%), Positives = 102/225 (45%), Gaps = 11/225 (4%)
Query: 1683 EDTKYTRTWFLASLMTAIVWGLGGILNTDSREKFDDLVKEYFKGEKGIPSKIERIDVSIP 1742
E TK T + + +W LGG L + + FD ++ F + D +P
Sbjct: 2 EQTKLN-TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQFD---------DNPDARLP 51
Query: 1743 AEGMLIDHFYMYKGKGCWKTWPDAVKAVQVKEQINLLQTVIPTLETEKFMYLLNLHSKYL 1802
G L + K W + + + + ++PT +T ++ YL+
Sbjct: 52 NSGDLWSIHMDFDTKRL-DPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVK 110
Query: 1803 KPLLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKN 1862
+L G TG GKS + L + Y P ++ S+ +TQ+++ SKL ++RKN
Sbjct: 111 HSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKN 170
Query: 1863 NYGPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLRLYFDQKHWYD 1907
G K +IF+DD+NMP + YG+QP IELLR Y D +YD
Sbjct: 171 ILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYD 215
Score = 48.8 bits (111), Expect = 4e-04
Identities = 19/36 (52%), Positives = 28/36 (77%)
Query: 1925 IAATTDIYDQARENLRPTPAKSHYIFNLRDFSRVIQ 1960
+ A+ +IY++ +L PTPAKSHY+FNLRD S+ +Q
Sbjct: 291 VEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQ 326
>U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 101 bits (242), Expect = 5e-20
Identities = 46/48 (95%), Positives = 46/48 (95%)
Query: 1234 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
PAGTGKTETTKDLAKALAVQCVVFNCSDGLDY AMGKFFKGLAS GAW
Sbjct: 1 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAW 48
>Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy chain
protein.
Length = 179
Score = 96.3 bits (229), Expect = 2e-18
Identities = 62/165 (37%), Positives = 82/165 (49%), Gaps = 29/165 (17%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW----------- 1281
GPAGTGKTE+ K L L Q +VFNC +G+D K+MG+ F GL CGAW
Sbjct: 1 GPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEE 60
Query: 1282 ---------------AVRQHLETFDFEGTTLKLNPACYVCITMNP---GYAGRSELPDNL 1323
A++ H + G +++N + ITMNP GY GR +LPDNL
Sbjct: 61 SVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSHSGIFITMNPAGKGYGGRQKLPDNL 120
Query: 1324 KVLFRTVAMMVPDYAMIEQLSSQNHYDYGMRAVKTVLSAAGNLKR 1368
K LFR VAM PD +I ++ + + + L A NL R
Sbjct: 121 KQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSR 165
>U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 91.5 bits (217), Expect = 5e-17
Identities = 41/48 (85%), Positives = 43/48 (89%)
Query: 1234 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
PAGTGKTETTKDL KALA+Q VVFNCSD LD+ AMGKFFKGLAS GAW
Sbjct: 1 PAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAW 48
>AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens cDNA
FLJ44002 fis, clone TESTI4022873. ).
Length = 1205
Score = 91.5 bits (217), Expect = 5e-17
Identities = 113/539 (20%), Positives = 222/539 (41%), Gaps = 58/539 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHNIADAISHISQRLMPIEQYLKIPYNYDALPVVYN 366
++++ LD G Y LE N+ D + + +E+ + P++ +
Sbjct: 660 IMDLVLDSSGVH-YSTPLEQFEASLLNLFDKGILATHAVPQLEKLVMEDIFISGDPLLES 718
Query: 367 EWLHKDGHERLQQQL-NIVFK---PLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
LH+ E L+ + + V K PL Y ++ R+ Y L L+ + + +
Sbjct: 719 VGLHEPLVEELRATIASAVSKAMIPLQAYAKEYRK-YLELNNNDIASFLKTYQTQGLLAQ 777
Query: 423 ELRNKIKYY----QDIDSNITA--VLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGI 476
E+R + + + +DS++ + ++ Y N V Q L + ++ +
Sbjct: 778 EVREVVLTHLREKEILDSSLPSSIIIGPFYINTDNVKQ-----SLSKKRKALATSVLDIL 832
Query: 477 VKGHMAENESICSEFEIIAAKALKEPENATELIEQGVYILHAKTVLVEALKERILVQINI 536
K E +SIC EF I+ K ++P + EL E ++ LV L+ERI+ ++
Sbjct: 833 AKNLHKEVDSICEEFRSISRKIYEKPNSIEELAELREWMKGIPERLV-GLEERIVKVMDD 891
Query: 537 ISNLLE-MTSLSSDHVKSNTRTVNW----LKDIKPIFEKNAAAYETFKADM---EESLLG 588
+ E + +LSSD NW L I+ + +++ E F+ + +
Sbjct: 892 YQVMDEFLYNLSSDDFNDKWIASNWPSKILGQIELVQQQHVEDEEKFRKIQIMDQNNFQE 951
Query: 589 KIAYLNKEVTDMTPYLELLDNMDDVNHTLEYLEYLRKLVHRLHDCDKLVTWINNEETTFK 648
K+ L V + ++E ++ E +R++ +L DC +L NN E F
Sbjct: 952 KLEGLQLVVAGFSIHVE-------ISRAHEIANEVRRVKKQLKDCQQLAMLYNNRERIFS 1004
Query: 649 FPVTNYPELEELKEFIIPFYSLVYLVHRWKRSYYTWMDGPFEYLDHNQIEQDHDFYYKEF 708
P+TNY +L + + P+ L W R +WM+ P +D Q+E++ +K
Sbjct: 1005 LPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAFKTM 1064
Query: 709 LKISKNYRNKIKQQIAEGVEKRFQGLVDDPDVNNLPAPMKLCAQAVAEIKDWRPNVQMAH 768
K K +++ +PA ++ A I++++P + +
Sbjct: 1065 HKCVKQFKD-------------------------MPACQEVALDIRARIEEFKPYIPLIQ 1099
Query: 769 IMCNPALVQRHWDEMSTIAGFDLTPTAGTSLRKIINFNLWGDLDQYEIISVAATKELAL 827
+ NP + RHW+ +S ++ P A + + + NL ++ ++ A KE A+
Sbjct: 1100 GLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAI 1158
>AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 89.0 bits (211), Expect = 3e-16
Identities = 40/57 (70%), Positives = 42/57 (73%)
Query: 1237 TGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
TGKTETTKDLAKALA+QCVVFNCSDGLD K MG+FF GLA GAW D E
Sbjct: 1 TGKTETTKDLAKALAIQCVVFNCSDGLDCKMMGRFFSGLAQSGAWCCFDEFNRIDIE 57
>U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein.
Length = 77
Score = 86.2 bits (204), Expect = 2e-15
Identities = 39/73 (53%), Positives = 47/73 (64%)
Query: 1209 TPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAM 1268
TPLTDRCY T+ A L G+P GPAGTGKTE+ K L L +VFNC + D++AM
Sbjct: 1 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 60
Query: 1269 GKFFKGLASCGAW 1281
G+ F GL GAW
Sbjct: 61 GRIFVGLCQVGAW 73
>AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 83
Score = 82.2 bits (194), Expect = 3e-14
Identities = 38/54 (70%), Positives = 40/54 (74%)
Query: 1240 TETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
TETTKDL KALA+Q VVFNCSD LD+ AMGKFFKGLAS GAWA D E
Sbjct: 1 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIE 54
>L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein.
Length = 141
Score = 81.4 bits (192), Expect = 6e-14
Identities = 37/71 (52%), Positives = 45/71 (63%)
Query: 1211 LTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGK 1270
LTDRCY T+ A L G+P GPAGTGKTE+ K L L +VFNC + D++AMG+
Sbjct: 1 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 60
Query: 1271 FFKGLASCGAW 1281
F GL GAW
Sbjct: 61 IFVGLCQVGAW 71
>AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 80.2 bits (189), Expect = 1e-13
Identities = 34/55 (61%), Positives = 39/55 (70%)
Query: 1237 TGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFD 1291
TGKTETTKDLAKAL + CVV NC +G+DY+A+GK F GLA CGAW D
Sbjct: 1 TGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRID 55
>BC117303-1|AAI17304.1| 1021|Homo sapiens dynein heavy chain domain 1
protein.
Length = 1021
Score = 77.8 bits (183), Expect = 7e-13
Identities = 94/426 (22%), Positives = 169/426 (39%), Gaps = 25/426 (5%)
Query: 2864 EIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDIL 2923
E+ + +++ L + LE+Q L ++ +E P+L+ + + L ++ A++ E+ +L
Sbjct: 8 ELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLL 67
Query: 2924 RTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLG-YRPIASHSA 2982
L + + + ++ + E LE + + E YRP+ H
Sbjct: 68 TMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCE-ELEGQKLQEMVLWAPYRPVVWHGM 126
Query: 2983 VLYYCVTELPNVDPMYQYSL-TWFI----NLYIISIENANKSKDLEKRLKFLKDTFTYNL 3037
+ +++L N+ P++ S W L + N +DL L L+ T L
Sbjct: 127 AMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQL 186
Query: 3038 YSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL-KKPVE---- 3092
+ +L + + ++ +T K + E L G A + + KPV
Sbjct: 187 LGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVAR 246
Query: 3093 --WLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQF 3150
WL KAW E L L F WQ PG E L+
Sbjct: 247 PAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLL 306
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSD 3210
QKL++ RVLRP+ L A++ F +GR + + F S P++ +L P
Sbjct: 307 QKLILWRVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGH 365
Query: 3211 PMGAL--IKYCERMGFSH-----RFNSISLG-QGQGPIARAM--IEKAQSEGGWVCLQNC 3260
P L + +++ + + I+LG + P++ + + +A EG W+ L NC
Sbjct: 366 PSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNC 425
Query: 3261 HLAVSW 3266
HL W
Sbjct: 426 HLMPHW 431
>BC117301-1|AAI17302.1| 1021|Homo sapiens dynein heavy chain domain 1
protein.
Length = 1021
Score = 77.8 bits (183), Expect = 7e-13
Identities = 94/426 (22%), Positives = 169/426 (39%), Gaps = 25/426 (5%)
Query: 2864 EIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDIL 2923
E+ + +++ L + LE+Q L ++ +E P+L+ + + L ++ A++ E+ +L
Sbjct: 8 ELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLL 67
Query: 2924 RTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLG-YRPIASHSA 2982
L + + + ++ + E LE + + E YRP+ H
Sbjct: 68 TMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCE-ELEGQKLQEMVLWAPYRPVVWHGM 126
Query: 2983 VLYYCVTELPNVDPMYQYSL-TWFI----NLYIISIENANKSKDLEKRLKFLKDTFTYNL 3037
+ +++L N+ P++ S W L + N +DL L L+ T L
Sbjct: 127 AMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQL 186
Query: 3038 YSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL-KKPVE---- 3092
+ +L + + ++ +T K + E L G A + + KPV
Sbjct: 187 LGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVAR 246
Query: 3093 --WLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQF 3150
WL KAW E L L F WQ PG E L+
Sbjct: 247 PAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLL 306
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSD 3210
QKL++ RVLRP+ L A++ F +GR + + F S P++ +L P
Sbjct: 307 QKLILWRVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGH 365
Query: 3211 PMGAL--IKYCERMGFSH-----RFNSISLG-QGQGPIARAM--IEKAQSEGGWVCLQNC 3260
P L + +++ + + I+LG + P++ + + +A EG W+ L NC
Sbjct: 366 PSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNC 425
Query: 3261 HLAVSW 3266
HL W
Sbjct: 426 HLMPHW 431
>AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy
chain 14 protein.
Length = 234
Score = 77.8 bits (183), Expect = 7e-13
Identities = 35/60 (58%), Positives = 39/60 (65%)
Query: 1234 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
PAGTGKTET KDLAK+L CVVFNC + LDYK + KFF GL GAW+ D E
Sbjct: 1 PAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLE 60
Score = 71.7 bits (168), Expect = 5e-11
Identities = 31/71 (43%), Positives = 49/71 (69%)
Query: 1341 EQLSSQNHYDYGMRAVKTVLSAAGNLKRSFPNESESVLLLRSITDVNLPKFLSFDVPLFE 1400
+QLS Q+HY++G+R++K VL AG KR E+++++ +I + +LPK DVPLFE
Sbjct: 164 KQLSQQDHYNFGLRSLKIVLIMAGTKKRDLSEADETLIVIEAIREASLPKCPPEDVPLFE 223
Query: 1401 GIISDLFPGIS 1411
II D+FP ++
Sbjct: 224 NIIGDIFPEVT 234
Score = 69.7 bits (163), Expect = 2e-10
Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 3/77 (3%)
Query: 1290 FDFEGTTLKLNPACYVCITMNPGYAGRSELPDNLKVLFRTVAMMVPDYAMIEQLSSQNHY 1349
F EG +++N +C V ITMNP Y G ELPDNLK LFR VAMMVP Y MI ++ +
Sbjct: 85 FVLEGKEIRINMSCAVFITMNPRYGGGVELPDNLKSLFRPVAMMVPHYQMIAEIIL---F 141
Query: 1350 DYGMRAVKTVLSAAGNL 1366
+G ++ ++ NL
Sbjct: 142 SFGFKSANSLSGKLTNL 158
>AK057314-1|BAB71423.1| 1021|Homo sapiens protein ( Homo sapiens cDNA
FLJ32752 fis, clone TESTI2001661, weakly similar to
DYNEIN BETA CHAIN, FLAGELLAR OUTER ARM. ).
Length = 1021
Score = 77.8 bits (183), Expect = 7e-13
Identities = 94/426 (22%), Positives = 169/426 (39%), Gaps = 25/426 (5%)
Query: 2864 EIFNKVTLINFALTKDGLEDQSLGIVVAKERPDLQEKREKLIVQGAANRAALKQVEDDIL 2923
E+ + +++ L + LE+Q L ++ +E P+L+ + + L ++ A++ E+ +L
Sbjct: 8 ELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLL 67
Query: 2924 RTLQETKGDILEDESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLG-YRPIASHSA 2982
L + + + ++ + E LE + + E YRP+ H
Sbjct: 68 TMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCE-ELEGQKLQEMVLWAPYRPVVWHGM 126
Query: 2983 VLYYCVTELPNVDPMYQYSL-TWFI----NLYIISIENANKSKDLEKRLKFLKDTFTYNL 3037
+ +++L N+ P++ S W L + N +DL L L+ T L
Sbjct: 127 AMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQL 186
Query: 3038 YSNVCRSLFDKDKLMFSFIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL-KKPVE---- 3092
+ +L + + ++ +T K + E L G A + + KPV
Sbjct: 187 LGSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVAR 246
Query: 3093 --WLPDKAWDEICRLNDLKAFRAFRDDFVKTIIKWQEVYDDIEPQNKTLPGGWDERLTQF 3150
WL KAW E L L F WQ PG E L+
Sbjct: 247 PAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLL 306
Query: 3151 QKLLVVRVLRPDKLTIAVSQFLEKEMGRKYTTPPPFDISKSFGDSNCLAPLIFILSPGSD 3210
QKL++ RVLRP+ L A++ F +GR + + F S P++ +L P
Sbjct: 307 QKLILWRVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGH 365
Query: 3211 PMGAL--IKYCERMGFSH-----RFNSISLG-QGQGPIARAM--IEKAQSEGGWVCLQNC 3260
P L + +++ + + I+LG + P++ + + +A EG W+ L NC
Sbjct: 366 PSATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNC 425
Query: 3261 HLAVSW 3266
HL W
Sbjct: 426 HLMPHW 431
>Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy chain
protein.
Length = 107
Score = 74.9 bits (176), Expect = 5e-12
Identities = 30/49 (61%), Positives = 38/49 (77%)
Query: 1233 GPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
GPAGTGKTETTKD+ + L VVFNCSD +D++ +G+ FKGLA G+W
Sbjct: 1 GPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSW 49
>U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein.
Length = 54
Score = 71.3 bits (167), Expect = 6e-11
Identities = 30/47 (63%), Positives = 36/47 (76%)
Query: 1235 AGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
AGTGKTETTKDL +AL + VFNCS+ +DYK+ G +KGLA GAW
Sbjct: 1 AGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAW 47
>U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 70.5 bits (165), Expect = 1e-10
Identities = 32/47 (68%), Positives = 35/47 (74%)
Query: 1234 PAGTGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGA 1280
PAGTGKTET KDLAK+L CVVFNC + LDYK + KFF GL GA
Sbjct: 1 PAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGA 47
>U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy chain
isotype1 protein.
Length = 89
Score = 69.7 bits (163), Expect = 2e-10
Identities = 32/48 (66%), Positives = 34/48 (70%)
Query: 1246 LAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
L KALA+Q VVFNCSD LD+ AMGKFFKGLAS GAWA D E
Sbjct: 1 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIE 48
>AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein.
Length = 207
Score = 69.7 bits (163), Expect = 2e-10
Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Query: 1823 LMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNYGPTRGKHAIIFIDDMNMP 1882
L+ N D + I +A +T+++++ KL++R K+ G + +IFIDDMNMP
Sbjct: 95 LLKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMP 154
Query: 1883 AKEVYGAQPAIELLRLYFDQKHWYDLKTTDKLFIYD-TIFYGAIAATTDI 1931
++YGAQP +EL+R D YD + I D +I + DI
Sbjct: 155 VSDMYGAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVNDI 204
>AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 69.3 bits (162), Expect = 2e-10
Identities = 41/101 (40%), Positives = 52/101 (51%), Gaps = 26/101 (25%)
Query: 1237 TGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW--------------- 1281
TGKTETTKDL +AL + VFNCS+ +DYK+ G +KGLA GAW
Sbjct: 1 TGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLS 60
Query: 1282 -----------AVRQHLETFDFEGTTLKLNPACYVCITMNP 1311
A+R + F F G + LNP+ + ITMNP
Sbjct: 61 VVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNP 101
>Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 68.5 bits (160), Expect = 4e-10
Identities = 44/91 (48%), Positives = 50/91 (54%), Gaps = 26/91 (28%)
Query: 1248 KALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAV------------------------ 1283
KALA+Q VVFNCSD LD+ AMGKFFKGLAS GAWA
Sbjct: 11 KALAIQTVVFNCSDLLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQK 70
Query: 1284 --RQHLETFDFEGTTLKLNPACYVCITMNPG 1312
+Q +E F FEG + L P+ V ITMNPG
Sbjct: 71 AQQQRVERFMFEGVEIPLVPSYAVFITMNPG 101
>AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 66.5 bits (155), Expect = 2e-09
Identities = 27/45 (60%), Positives = 34/45 (75%)
Query: 1237 TGKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
TGKTETTKDL +AL + VFNCS+ +DYK++G +KGL GAW
Sbjct: 1 TGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAW 45
>Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 64.1 bits (149), Expect = 9e-09
Identities = 37/101 (36%), Positives = 51/101 (50%), Gaps = 26/101 (25%)
Query: 1238 GKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW---------------- 1281
GKTE+TKDL +A+ + VFNCS+ +DY++ G +KGLA GAW
Sbjct: 1 GKTESTKDLGRAIGIMVYVFNCSEQMDYQSCGNIYKGLAQTGAWACFDEFNRITVEVLSV 60
Query: 1282 ----------AVRQHLETFDFEGTTLKLNPACYVCITMNPG 1312
A+R +TF+F G + P + ITMNPG
Sbjct: 61 VAVQVKSVQDAIRDKKDTFNFMGEIISCVPTVGIFITMNPG 101
>Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 62.5 bits (145), Expect = 3e-08
Identities = 39/101 (38%), Positives = 49/101 (48%), Gaps = 26/101 (25%)
Query: 1238 GKTETTKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW---------------- 1281
GKTETTKDL + L VFNCS+ +DYK+ G +KGLA GAW
Sbjct: 1 GKTETTKDLDRPLGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLYV 60
Query: 1282 ----------AVRQHLETFDFEGTTLKLNPACYVCITMNPG 1312
A+R + F+F G + L P + ITMNPG
Sbjct: 61 IAVQVKCVQDAIRAKKKKFNFLGEIISLVPTVGIFITMNPG 101
>AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein.
Length = 1007
Score = 56.8 bits (131), Expect = 1e-06
Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 32/213 (15%)
Query: 1094 WAVDVHESLNTHKLSELQAF-HSELTKQLNETVAVIRRTDLTKLSSITVKALIVIDVHAK 1152
W S++ KL L F ++ Q +++ +R+T L + AL+V+ V +
Sbjct: 219 WGTLAMVSMHMRKLEVLVNFMRAQRASQGGQSLPSVRQTSL-------LSALLVMAVTHR 271
Query: 1153 DVISDLIKKKVTEVTDFQWLAQLRYYWEEERV------------------------YVKI 1188
D+ L + +V+++TDF W+ QL+Y+ + ++ +
Sbjct: 272 DIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASSEPSLSPAACWIDV 331
Query: 1189 INAVVHYAYEYLGNSDRLVITPLTDRCYRTLIGAYYLHLNGAPEGPAGTGKTETTKDLAK 1248
+ Y YEYLG + + L +R L+ A G GP G GK LA+
Sbjct: 332 LGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVNSLAQ 391
Query: 1249 ALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
AL Q V+ CS ++ + + + G GAW
Sbjct: 392 ALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAW 424
Score = 46.4 bits (105), Expect = 0.002
Identities = 19/71 (26%), Positives = 38/71 (53%)
Query: 1532 EDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSMIFEVMDLSQAS 1591
E ++ WI+ DG + W++++ +L + +L L SG+ +A ++ EV D + S
Sbjct: 769 ESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGIS 828
Query: 1592 PATVSRCGMIY 1602
P V C +++
Sbjct: 829 PTVVGCCALVW 839
Score = 38.3 bits (85), Expect = 0.53
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 5/111 (4%)
Query: 939 GTGILEAFRAATAFLEKINDGVNNYLEKKRLYFPRFFFLSNDEMLEILSETKNPLKVQPH 998
G + + +A + LE I + + L +FPR FFLS+ E++ +L+ + Q
Sbjct: 13 GQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLW 72
Query: 999 LKKCFEGINRLVF----DGEFNISAMISMEGEQVEFLDMISVAAARGSVEK 1045
+++CF ++ + F GE N S Q + ++ ++V A G K
Sbjct: 73 VRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQ-VEALAVLGAGGEEVK 122
>AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 53.6 bits (123), Expect = 1e-05
Identities = 21/49 (42%), Positives = 29/49 (59%)
Query: 1243 TKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFD 1291
TKD+ + L VVFNCSD +D++ +G+ FKGLA G+W D
Sbjct: 1 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRID 49
>AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 53.2 bits (122), Expect = 2e-05
Identities = 20/39 (51%), Positives = 28/39 (71%)
Query: 1243 TKDLAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
TKD+ + L VVFNCSD +D++ +G+ FKGLA G+W
Sbjct: 1 TKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSW 39
>AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein
protein.
Length = 94
Score = 51.6 bits (118), Expect = 5e-05
Identities = 27/83 (32%), Positives = 44/83 (53%)
Query: 1395 DVPLFEGIISDLFPGISLPKPDYENFLNACHDVCENNNLQPMECFLIKVIQTYEMMIVRH 1454
D F+ +I D+FPGI L + +Y+ A V E N + + + K ++ YE + R
Sbjct: 4 DCTRFDALIKDVFPGIKLKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRM 63
Query: 1455 GFMLVGNPFSGKSMTLKVLSEAL 1477
G ++VG +GKS ++L AL
Sbjct: 64 GVVIVGPSGAGKSTLWRMLRAAL 86
>AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 67
Score = 50.0 bits (114), Expect = 2e-04
Identities = 21/33 (63%), Positives = 22/33 (66%)
Query: 1261 DGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
DGLDY A+GKFFKGL SCGAWA D E
Sbjct: 1 DGLDYLALGKFFKGLLSCGAWACFDEFNRIDLE 33
>U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy chain
isotype2 protein.
Length = 83
Score = 49.2 bits (112), Expect = 3e-04
Identities = 19/44 (43%), Positives = 26/44 (59%)
Query: 1250 LAVQCVVFNCSDGLDYKAMGKFFKGLASCGAWAVRQHLETFDFE 1293
L + +V NCS+GLDYK+MG+ + GLA GAW + E
Sbjct: 1 LGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIE 44
>AK094515-1|BAC04372.1| 501|Homo sapiens protein ( Homo sapiens
cDNA FLJ37196 fis, clone BRALZ2005888. ).
Length = 501
Score = 49.2 bits (112), Expect = 3e-04
Identities = 52/256 (20%), Positives = 114/256 (44%), Gaps = 19/256 (7%)
Query: 101 PMLKSWERKIRNLIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTVIRDV--PGVPR 158
PM SW + +L+P +L+ F + L +E ++++ ++ V V++D G +
Sbjct: 179 PMEDSWLEHVLDLVPQHLKV-FTDSIVTLSDEMREDYLLSVRKSIVDFVLKDPREKGDDK 237
Query: 159 KRYEEPHFK--FKGVTSNYGK-LLKYRRKLQDGSLLLHPFIRLILESSEKTFP-LHIIDL 214
K E P + + + + K L ++D ++P + +L+ F L ++D+
Sbjct: 238 KTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNPTMLAVLDLWHTNFKKLRLVDI 297
Query: 215 AKYR-AKGPMSLDEFRLKVLDEIKRADYLVSSTWY----GILVQWLKNPRCLKGMKPRKV 269
++ + + L F+ ++ + A + W+ I Q K + G K+
Sbjct: 298 KEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPEVQNIYYQGNKKKQLPTGDSSAKL 357
Query: 270 NDFVKCATKMISMQIQELMRQSINAIIDFL-KDPEAI-----PVLNVCLDFDGEFI-YDP 322
F CA ++++Q+Q+L S+ D + + P+++ P + L D + I ++P
Sbjct: 358 ESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPDSVRAFEHPGFIMRLILDNDTIKFEP 417
Query: 323 TLETIYEVFHNIADAI 338
L ++F N+ D +
Sbjct: 418 ELSDYIDIFLNVYDVV 433
>U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy chain
isotype 11 protein.
Length = 37
Score = 47.6 bits (108), Expect = 9e-04
Identities = 18/36 (50%), Positives = 25/36 (69%)
Query: 1246 LAKALAVQCVVFNCSDGLDYKAMGKFFKGLASCGAW 1281
L +AL + VFNCS+ +DYK++G +KGL GAW
Sbjct: 1 LGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAW 36
>AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein
protein.
Length = 617
Score = 46.4 bits (105), Expect = 0.002
Identities = 19/71 (26%), Positives = 38/71 (53%)
Query: 1532 EDTPVRKWIVFDGPVDAVWIENMNTVLDDNKKLCLTSGEVMAMSNVMSMIFEVMDLSQAS 1591
E ++ WI+ DG + W++++ +L + +L L SG+ +A ++ EV D + S
Sbjct: 379 ESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGIS 438
Query: 1592 PATVSRCGMIY 1602
P V C +++
Sbjct: 439 PTVVGCCALVW 449
>AK056509-1|BAE46616.1| 753|Homo sapiens protein ( Homo sapiens
cDNA FLJ31947 fis, clone NT2RP7006995, highly similar
to Homo sapiens dynein, axonemal, heavy polypeptide 3
(DNAH3). ).
Length = 753
Score = 46.0 bits (104), Expect = 0.003
Identities = 41/191 (21%), Positives = 83/191 (43%), Gaps = 6/191 (3%)
Query: 397 QEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDSNITAVLENEYFNCAVVC--Q 454
++Y L A++ + F+ E ++ KI + + I ++ N A+ C
Sbjct: 551 KKYVDLLDNTAEQNIAAFLKENHDIDDFVTKINAIKKRRNEIASM--NITVPLAMFCLDA 608
Query: 455 LRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAAKALKEPENATELIEQGVY 514
+ L RA + +I V + N SIC+++ IA K + P N EL+ +
Sbjct: 609 TALNHDLCERAQNLKDHLIQFQVDVNRDTNTSICNQYSHIADKVSEVPANTKELVSLIEF 668
Query: 515 ILHAKTVLVEALKERILVQINIISNLLEMTSLSSDHVKSNTRTVNWLKDIKPIFE--KNA 572
+ + V V L+ ++ + L++ L + +K N+ W I+ IF+ +N
Sbjct: 669 LKKSSAVTVFKLRRQLRDASERLEFLMDYADLPYEDIKLNSTLFLWPDQIEDIFDNSRNL 728
Query: 573 AAYETFKADME 583
++ +A+M+
Sbjct: 729 LLHKRDQAEMD 739
>D86956-1|BAA13192.2| 949|Homo sapiens KIAA0201 protein.
Length = 949
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 701 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 760
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 761 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 808
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 809 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 866
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 867 QDPVVRAQ-EI--KTKIKELNNTCE 888
>BC037553-1|AAH37553.1| 858|Homo sapiens heat shock 105kDa/110kDa
protein 1 protein.
Length = 858
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 610 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 669
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 670 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 717
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 718 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 775
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 776 QDPVVRAQ-EI--KTKIKELNNTCE 797
>AL137142-5|CAI12430.1| 858|Homo sapiens heat shock 105kDa/110kDa
protein 1 protein.
Length = 858
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 610 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 669
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 670 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 717
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 718 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 775
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 776 QDPVVRAQ-EI--KTKIKELNNTCE 797
>AL137142-4|CAI12428.1| 814|Homo sapiens heat shock 105kDa/110kDa
protein 1 protein.
Length = 814
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 566 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 625
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 626 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 673
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 674 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 731
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 732 QDPVVRAQ-EI--KTKIKELNNTCE 753
>AL137142-3|CAI12429.1| 817|Homo sapiens heat shock 105kDa/110kDa
protein 1 protein.
Length = 817
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 569 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 628
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 629 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 676
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 677 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 734
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 735 QDPVVRAQ-EI--KTKIKELNNTCE 756
>AF039695-1|AAC18044.1| 872|Homo sapiens antigen NY-CO-25 protein.
Length = 872
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 624 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 683
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 684 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 731
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 732 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 789
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 790 QDPVVRAQ-EI--KTKIKELNNTCE 811
>AB003334-1|BAA34780.1| 858|Homo sapiens HSP105 alpha protein.
Length = 858
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 610 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 669
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 670 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 717
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 718 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 775
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 776 QDPVVRAQ-EI--KTKIKELNNTCE 797
>AB003333-1|BAA34779.1| 814|Homo sapiens HSP105 beta protein.
Length = 814
Score = 41.5 bits (93), Expect = 0.057
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 21/205 (10%)
Query: 307 VLNVCLDFDGEFIYDPTLETIYEVFHN-IADAISHISQRLM-PIEQYL--KIPYNYDALP 362
+LN+ ++ +G+ I LE N + + + +L P E+++ + N+ L
Sbjct: 566 LLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 625
Query: 363 VVYNEWLHKDGHERLQQQLNIVFKPLNQYVEKLRQEYNMLYGTPAKEALEKFINETEAFE 422
+WL+++G ++ +Q YV+KL E M GTP K ++ + FE
Sbjct: 626 TETEDWLYEEGEDQAKQA----------YVDKL--EELMKIGTPVKVRFQEAEERPKMFE 673
Query: 423 ELRNKIKYYQDIDSNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMA 482
EL ++++Y I ++ ++E +N +++ V+ + +E++N+++ K +
Sbjct: 674 ELGQRLQHYAKIAADFRN--KDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD 731
Query: 483 ENESICSEFEIIAAKALKEPENATE 507
++ + ++ EI +KE N E
Sbjct: 732 QDPVVRAQ-EI--KTKIKELNNTCE 753
>BC064521-1|AAH64521.1| 197|Homo sapiens DYNC1H1 protein protein.
Length = 197
Score = 40.7 bits (91), Expect = 0.10
Identities = 19/77 (24%), Positives = 42/77 (54%)
Query: 3559 QEMERFNKLLNEIKSSLQDLQKAVKGLIVMSPALDLQSNAMLLGKIPENWRKFSYPSLKP 3618
+E++ KLL +++ L D+ + +G + L N ++ G +P +W ++ P+
Sbjct: 77 REVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMT 136
Query: 3619 LPSYVADFIERLSMLED 3635
+ +V+DF ER+ L++
Sbjct: 137 VIQWVSDFSERIKQLQN 153
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 38.7 bits (86), Expect = 0.40
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 8/215 (3%)
Query: 378 QQQLNIVFKPLNQYVEKL--RQEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDID 435
QQ+LN + L+Q KL +QE+ + KE EK+++ + EEL +IK +
Sbjct: 680 QQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADS 739
Query: 436 SNITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIA 495
+ A E + QL L++ L ++ IV + + E I
Sbjct: 740 LEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIK 799
Query: 496 AKALKEPENATELIEQGVYILHAKT-VLVEALKERILVQINIISNL-LEMTSLSSD--HV 551
K K+ E ++++Q L +T + E L RI + + + +E +L ++ V
Sbjct: 800 QKLTKQ-EEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV 858
Query: 552 KSN-TRTVNWLKDIKPIFEKNAAAYETFKADMEES 585
K ++ + LK+ K FEK + D+E++
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKT 893
>AY028079-1|AAK21976.1| 282|Homo sapiens putative protein protein.
Length = 282
Score = 38.7 bits (86), Expect = 0.40
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 6/97 (6%)
Query: 53 KILEEKATKRKVEIARPLLELYERDRLVESQSKHIGVLRECAEKIKAPPMLKSWERKIRN 112
K+ ++ +K E R +L L+ +++ E+ KH +L+EC E+I A + E+ +
Sbjct: 59 KVHLKEILSKKQETLR-ILRLHCQEKESEAHRKHT-MLQECKERISALNLQIEEEKNKQR 116
Query: 113 LIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTV 149
LR +F +E+LM + KD WD ++ + K +
Sbjct: 117 ----QLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEI 149
>AY027807-1|AAK14796.1| 282|Homo sapiens unknown protein.
Length = 282
Score = 38.7 bits (86), Expect = 0.40
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 6/97 (6%)
Query: 53 KILEEKATKRKVEIARPLLELYERDRLVESQSKHIGVLRECAEKIKAPPMLKSWERKIRN 112
K+ ++ +K E R +L L+ +++ E+ KH +L+EC E+I A + E+ +
Sbjct: 59 KVHLKEILSKKQETLR-ILRLHCQEKESEAHRKHT-MLQECKERISALNLQIEEEKNKQR 116
Query: 113 LIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTV 149
LR +F +E+LM + KD WD ++ + K +
Sbjct: 117 ----QLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEI 149
>AL161645-3|CAH70048.1| 282|Homo sapiens novel protein protein.
Length = 282
Score = 38.7 bits (86), Expect = 0.40
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 6/97 (6%)
Query: 53 KILEEKATKRKVEIARPLLELYERDRLVESQSKHIGVLRECAEKIKAPPMLKSWERKIRN 112
K+ ++ +K E R +L L+ +++ E+ KH +L+EC E+I A + E+ +
Sbjct: 59 KVHLKEILSKKQETLR-ILRLHCQEKESEAHRKHT-MLQECKERISALNLQIEEEKNKQR 116
Query: 113 LIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTV 149
LR +F +E+LM + KD WD ++ + K +
Sbjct: 117 ----QLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEI 149
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 36.7 bits (81), Expect = 1.6
Identities = 50/214 (23%), Positives = 92/214 (42%), Gaps = 8/214 (3%)
Query: 379 QQLNIVFKPLNQYVEKL--RQEYNMLYGTPAKEALEKFINETEAFEELRNKIKYYQDIDS 436
Q+LN + L+Q KL +QE+ + KE EK+++ + EEL +IK +
Sbjct: 681 QELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSL 740
Query: 437 NITAVLENEYFNCAVVCQLRMVDGLKSRALEFVNDIIAGIVKGHMAENESICSEFEIIAA 496
+ A E + QL L++ L ++ IV + + E I
Sbjct: 741 EVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ 800
Query: 497 KALKEPENATELIEQGVYILHAKT-VLVEALKERILVQINIISNL-LEMTSLSSD--HVK 552
K K+ E ++++Q L +T + E L RI + + + +E +L ++ VK
Sbjct: 801 KLTKQ-EEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVK 859
Query: 553 SN-TRTVNWLKDIKPIFEKNAAAYETFKADMEES 585
++ + LK+ K FEK + D+E++
Sbjct: 860 DKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKT 893
>BC034821-1|AAH34821.1| 315|Homo sapiens SYCE1 protein protein.
Length = 315
Score = 36.3 bits (80), Expect = 2.2
Identities = 25/97 (25%), Positives = 51/97 (52%), Gaps = 6/97 (6%)
Query: 53 KILEEKATKRKVEIARPLLELYERDRLVESQSKHIGVLRECAEKIKAPPMLKSWERKIRN 112
K+ ++ +K E R +L L+ +++ E+ KH +L++C E+I A + E+ +
Sbjct: 59 KVHLKEILSKKQETLR-ILRLHCQEKESEAHRKHT-MLQDCKERISALNLQIEEEKNKQR 116
Query: 113 LIPANLRQSFPTLVEELMNESKDEWDRNLHDLAVKTV 149
LR +F +E+LM + KD WD ++ + + +
Sbjct: 117 ----QLRLAFEEQLEDLMGQHKDLWDFHMPERLAREI 149
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 878 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 937
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 938 NQQRLLQTLETITNKLKRTLNK 959
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 3548
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 855 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 914
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 915 NQQRLLQTLETITNKLKRTLNK 936
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 3548
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 855 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 914
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 915 NQQRLLQTLETITNKLKRTLNK 936
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 3548
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 855 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 914
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 915 NQQRLLQTLETITNKLKRTLNK 936
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens
cDNA FLJ14964 fis, clone PLACE4000581, moderately
similar to FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 645 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 704
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 705 NQQRLLQTLETITNKLKRTLNK 726
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 36.3 bits (80), Expect = 2.2
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 317 EFIYDPTLETIYEVFHNIADAISHISQRLMPIEQY-LKIPYNYDA---LPVVYNEWLHKD 372
++ YD L+T+ E +I +A S +R P+ Y +K+ +N A LP N+ L +
Sbjct: 878 DYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWE 937
Query: 373 GHERLQQQLNIVFKPLNQYVEK 394
+RL Q L + L + + K
Sbjct: 938 NQQRLLQTLETITNKLKRTLNK 959
>X68985-1|CAA48777.1| 295|Homo sapiens hepatic leukemia factor
protein.
Length = 295
Score = 35.5 bits (78), Expect = 3.8
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDF 3382
RS + PLK P +E KDK K L S V Q GP W+ ++ F
Sbjct: 23 RSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAF-LGPTLWDKTLPYDGDTF 81
Query: 3383 QISVMQLQMFLNQ 3395
Q+ M L+ FL++
Sbjct: 82 QLEYMDLEEFLSE 94
>M95585-1|AAA52675.1| 295|Homo sapiens hepatic leukemia factor
protein.
Length = 295
Score = 35.5 bits (78), Expect = 3.8
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDF 3382
RS + PLK P +E KDK K L S V Q GP W+ ++ F
Sbjct: 23 RSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAF-LGPTLWDKTLPYDGDTF 81
Query: 3383 QISVMQLQMFLNQ 3395
Q+ M L+ FL++
Sbjct: 82 QLEYMDLEEFLSE 94
>CR541672-1|CAG46473.1| 295|Homo sapiens HLF protein.
Length = 295
Score = 35.5 bits (78), Expect = 3.8
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDF 3382
RS + PLK P +E KDK K L S V Q GP W+ ++ F
Sbjct: 23 RSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAF-LGPTLWDKTLPYDGDTF 81
Query: 3383 QISVMQLQMFLNQ 3395
Q+ M L+ FL++
Sbjct: 82 QLEYMDLEEFLSE 94
>BC036093-1|AAH36093.1| 295|Homo sapiens hepatic leukemia factor
protein.
Length = 295
Score = 35.5 bits (78), Expect = 3.8
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 3323 RSYISEPLKEPEFYEGCPGKDKTFSKLLYGISFFHAVVQERKKFGPLGWNIQYGFNDSDF 3382
RS + PLK P +E KDK K L S V Q GP W+ ++ F
Sbjct: 23 RSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAF-LGPTLWDKTLPYDGDTF 81
Query: 3383 QISVMQLQMFLNQ 3395
Q+ M L+ FL++
Sbjct: 82 QLEYMDLEEFLSE 94
>BC130373-1|AAI30374.1| 633|Homo sapiens ClpX caseinolytic peptidase
X homolog (E. coli) protein.
Length = 633
Score = 34.7 bits (76), Expect = 6.6
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 1805 LLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNY 1864
+LL+GPTG+GK+ Q L LD+ + + VI+KL+ + NY
Sbjct: 289 ILLLGPTGSGKTLLAQT-LAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLL--QDANY 345
Query: 1865 GPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLR 1897
+ + I+F+D++ + G+ P I LR
Sbjct: 346 NVEKAQQGIVFLDEV-----DKIGSVPGIHQLR 373
>AJ276980-1|CAC01291.1| 633|Homo sapiens ClpX protein protein.
Length = 633
Score = 34.7 bits (76), Expect = 6.6
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 1805 LLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNY 1864
+LL+GPTG+GK+ Q L LD+ + + VI+KL+ + NY
Sbjct: 289 ILLLGPTGSGKTLLAQT-LAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLL--QDANY 345
Query: 1865 GPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLR 1897
+ + I+F+D++ + G+ P I LR
Sbjct: 346 NVEKAQQGIVFLDEV-----DKIGSVPGIHQLR 373
>AJ006267-1|CAA06933.2| 633|Homo sapiens ClpX-like protein protein.
Length = 633
Score = 34.7 bits (76), Expect = 6.6
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 1805 LLLIGPTGTGKSFYVQNFLMNNLDMEKYTPGFIXXXXXXSANQTQDLVISKLVKRRKNNY 1864
+LL+GPTG+GK+ Q L LD+ + + VI+KL+ + NY
Sbjct: 289 ILLLGPTGSGKTLLAQT-LAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLL--QDANY 345
Query: 1865 GPTRGKHAIIFIDDMNMPAKEVYGAQPAIELLR 1897
+ + I+F+D++ + G+ P I LR
Sbjct: 346 NVEKAQQGIVFLDEV-----DKIGSVPGIHQLR 373
>AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 34.3 bits (75), Expect = 8.7
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 2937 ESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDP 2996
E I + +N+A + ++ +LE E + + + + SH+ + T L +V P
Sbjct: 834 ELTIATKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAV-SHAKAPFTSATHLDHVRP 892
Query: 2997 MYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLY--SNVCRSLFDKDKLMFS 3054
M++ T + Y I ++N + ++ L+ ++ + R + + FS
Sbjct: 893 MFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFS 952
Query: 3055 FIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL 3087
+ S + ++ N+D K LIT N+L
Sbjct: 953 LLTASSSITEMKQKNIDTIKTLITVAHTDGNYL 985
>AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 34.3 bits (75), Expect = 8.7
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 2937 ESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDP 2996
E I + +N+A + ++ +LE E + + + + SH+ + T L +V P
Sbjct: 834 ELTIATKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAV-SHAKAPFTSATHLDHVRP 892
Query: 2997 MYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLY--SNVCRSLFDKDKLMFS 3054
M++ T + Y I ++N + ++ L+ ++ + R + + FS
Sbjct: 893 MFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFS 952
Query: 3055 FIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL 3087
+ S + ++ N+D K LIT N+L
Sbjct: 953 LLTASSSITEMKQKNIDTIKTLITVAHTDGNYL 985
>AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 2 protein.
Length = 1785
Score = 34.3 bits (75), Expect = 8.7
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 2937 ESAIEVLDSSKNLAIDIMKKQEASLETETIIEKFRLGYRPIASHSAVLYYCVTELPNVDP 2996
E I + +N+A + ++ +LE E + + + + SH+ + T L +V P
Sbjct: 834 ELTIATKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAV-SHAKAPFTSATHLDHVRP 892
Query: 2997 MYQYSLTWFINLYIISIENANKSKDLEKRLKFLKDTFTYNLY--SNVCRSLFDKDKLMFS 3054
M++ T + Y I ++N + ++ L+ ++ + R + + FS
Sbjct: 893 MFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAIRIACIFGMQLERDAYVQALARFS 952
Query: 3055 FIMCSKMMLSTEKMNVDEYKFLITGGIAVENHL 3087
+ S + ++ N+D K LIT N+L
Sbjct: 953 LLTASSSITKMKQKNIDTIKTLITVAHTDGNYL 985
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 540,585,789
Number of Sequences: 224733
Number of extensions: 23026071
Number of successful extensions: 54231
Number of sequences better than 10.0: 150
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 52687
Number of HSP's gapped (non-prelim): 682
length of query: 3796
length of database: 73,234,838
effective HSP length: 105
effective length of query: 3691
effective length of database: 49,637,873
effective search space: 183213389243
effective search space used: 183213389243
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)
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