Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001865-TA|BGIBMGA001865-PA|IPR008089|Nucleotide sugar
epimerase, IPR005886|UDP-glucose 4-epimerase, IPR001509|NAD-dependent
epimerase/dehydratase
(234 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q14376 Cluster: UDP-glucose 4-epimerase; n=150; cellula... 282 6e-75
UniRef50_Q9T0A7 Cluster: Probable UDP-glucose 4-epimerase At4g23... 271 9e-72
UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular o... 252 6e-66
UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20; Viridipl... 252 7e-66
UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellula... 244 1e-63
UniRef50_Q8H931 Cluster: Putative UDP-glucose 4-epimerase; n=5; ... 241 8e-63
UniRef50_UPI0000DAE763 Cluster: hypothetical protein Rgryl_01001... 236 4e-61
UniRef50_Q0IDK5 Cluster: UDP-glucose 4-epimerase; n=3; Cyanobact... 226 4e-58
UniRef50_P04397 Cluster: Bifunctional protein GAL10 [Includes: U... 224 1e-57
UniRef50_A5GHV3 Cluster: UDP-glucose-4-epimerase; n=11; Cyanobac... 223 3e-57
UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco... 223 4e-57
UniRef50_Q7VAY9 Cluster: UDP-glucose 4-epimerase; n=2; Prochloro... 219 4e-56
UniRef50_Q7MX67 Cluster: UDP-glucose 4-epimerase; n=12; Bacteroi... 218 9e-56
UniRef50_A6RJ24 Cluster: Putative uncharacterized protein; n=2; ... 215 6e-55
UniRef50_A1ZWK4 Cluster: UDP-glucose 4-epimerase; n=16; Bacteroi... 213 3e-54
UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases... 212 6e-54
UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1; ... 203 3e-51
UniRef50_A3PE72 Cluster: UDP-glucose 4-epimerase; n=2; Prochloro... 202 5e-51
UniRef50_A0VUL2 Cluster: UDP-glucose 4-epimerase; n=2; Rhodobact... 201 1e-50
UniRef50_Q0U254 Cluster: Putative uncharacterized protein; n=1; ... 196 4e-49
UniRef50_A2R0Z8 Cluster: Catalytic activity: UDPglucose = UDPgal... 196 4e-49
UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5; Bacteria|... 195 9e-49
UniRef50_Q5K809 Cluster: Galactose metabolism-related protein, p... 194 1e-48
UniRef50_Q5QPP4 Cluster: UDP-galactose-4-epimerase; n=6; cellula... 194 2e-48
UniRef50_Q5QXD9 Cluster: UDP-glucose 4-epimerase; n=1; Idiomarin... 190 3e-47
UniRef50_A5AK58 Cluster: Putative uncharacterized protein; n=1; ... 187 2e-46
UniRef50_Q2UPV8 Cluster: UDP-glucose 4-epimerase; n=7; Trichocom... 187 2e-46
UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15; Bacteria... 186 6e-46
UniRef50_Q4WQU9 Cluster: UDP-glucose 4-epimerase; n=3; Pezizomyc... 185 1e-45
UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobact... 182 7e-45
UniRef50_UPI00006CC433 Cluster: UDP-glucose 4-epimerase family p... 180 4e-44
UniRef50_A2BSF0 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 179 5e-44
UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1; Synechoco... 175 6e-43
UniRef50_Q8YN57 Cluster: UDP-glucose 4-epimerase; n=43; Bacteria... 175 1e-42
UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:... 174 1e-42
UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomy... 174 2e-42
UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellula... 173 2e-42
UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17; Bacteria... 171 2e-41
UniRef50_P96995 Cluster: UDP-glucose 4-epimerase; n=51; Bacteria... 171 2e-41
UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3; Alphaprot... 170 2e-41
UniRef50_Q9SA77 Cluster: UDP-arabinose 4-epimerase 1; n=31; Viri... 169 7e-41
UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria... 166 5e-40
UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 165 6e-40
UniRef50_A6LLZ0 Cluster: UDP-glucose 4-epimerase; n=2; Bacteria|... 165 8e-40
UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|R... 161 2e-38
UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3; Bacteria|... 158 1e-37
UniRef50_Q011T8 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 155 7e-37
UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4; Bacteria|... 154 2e-36
UniRef50_A0LVI8 Cluster: UDP-glucose 4-epimerase; n=6; Actinomyc... 151 2e-35
UniRef50_Q604T5 Cluster: UDP-glucose 4-epimerase; n=26; Proteoba... 147 2e-34
UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivall... 146 3e-34
UniRef50_A2BZ28 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 146 3e-34
UniRef50_A0CJT6 Cluster: Chromosome undetermined scaffold_2, who... 146 4e-34
UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomona... 145 1e-33
UniRef50_A0Z893 Cluster: UDP-glucose 4-epimerase; n=1; marine ga... 145 1e-33
UniRef50_UPI0000383ECD Cluster: COG1087: UDP-glucose 4-epimerase... 144 2e-33
UniRef50_Q1QJ29 Cluster: UDP-glucose 4-epimerase; n=1; Nitrobact... 143 3e-33
UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococc... 141 2e-32
UniRef50_Q8KGE4 Cluster: UDP-glucose 4-epimerase; n=14; Bacteria... 140 4e-32
UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2; Rhodospir... 140 4e-32
UniRef50_UPI000023E28B Cluster: hypothetical protein FG07983.1; ... 139 5e-32
UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2; Fusobacte... 139 6e-32
UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1; ... 139 6e-32
UniRef50_A6QU99 Cluster: UDP-glucose 4-epimerase; n=1; Ajellomyc... 139 6e-32
UniRef50_A1SPC3 Cluster: UDP-glucose 4-epimerase precursor; n=2;... 138 1e-31
UniRef50_UPI00015BC7D2 Cluster: UPI00015BC7D2 related cluster; n... 135 8e-31
UniRef50_Q8G3T3 Cluster: UDP-glucose 4-epimerase; n=5; Actinobac... 132 1e-29
UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1; Leptospir... 132 1e-29
UniRef50_Q9L047 Cluster: UDP-glucose 4-epimerase; n=7; Actinomyc... 128 9e-29
UniRef50_Q6KI97 Cluster: Udp-glucose 4-epimerase; n=1; Mycoplasm... 128 1e-28
UniRef50_A3VS38 Cluster: UDP-glucose 4-epimerase; n=2; Alphaprot... 128 2e-28
UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20; Bacteria... 125 1e-27
UniRef50_A4AI37 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 124 2e-27
UniRef50_Q6MS04 Cluster: UDP-glucose 4-epimerase; n=3; Mycoplasm... 124 3e-27
UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6; Actinobac... 122 6e-27
UniRef50_Q7VJ63 Cluster: UDP-glucose 4-epimerase; n=30; Epsilonp... 121 1e-26
UniRef50_A0LJ03 Cluster: UDP-glucose 4-epimerase; n=1; Syntropho... 119 7e-26
UniRef50_Q4Q3V7 Cluster: Udp-glc 4'-epimerase, putative; n=7; Tr... 119 7e-26
UniRef50_Q07GF0 Cluster: UDP-glucose 4-epimerase; n=1; Roseobact... 117 2e-25
UniRef50_Q2MFK2 Cluster: Putative apramycin biosynthetic oxidore... 106 4e-22
UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;... 105 1e-21
UniRef50_A4VWA8 Cluster: UDP-glucose 4-epimerase; n=1; Streptoco... 99 8e-20
UniRef50_Q6FB43 Cluster: Putative UDP-galactose 4-epimerase; n=2... 94 3e-18
UniRef50_P47364 Cluster: UDP-glucose 4-epimerase; n=4; Mycoplasm... 93 4e-18
UniRef50_Q2JEQ1 Cluster: NAD-dependent epimerase/dehydratase; n=... 89 7e-17
UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=... 85 2e-15
UniRef50_Q2RMP3 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 6e-15
UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 6e-15
UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcul... 83 6e-15
UniRef50_A4WHT4 Cluster: NAD-dependent epimerase/dehydratase; n=... 83 6e-15
UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3; ... 81 2e-14
UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1; ... 80 5e-14
UniRef50_A0RWB8 Cluster: Nucleoside-diphosphate-sugar epimerase;... 79 1e-13
UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=... 78 2e-13
UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase... 77 3e-13
UniRef50_Q20YR4 Cluster: NAD-dependent epimerase/dehydratase; n=... 77 5e-13
UniRef50_Q6I4D4 Cluster: UDP-glucose 4-epimerase, C-terminus; n=... 76 9e-13
UniRef50_Q1V1Y0 Cluster: UDPglucose 4-epimerase; n=2; Candidatus... 76 9e-13
UniRef50_A0FWU5 Cluster: NAD-dependent epimerase/dehydratase; n=... 76 9e-13
UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=... 75 2e-12
UniRef50_Q97NY4 Cluster: NAD-dependent epimerase/dehydratase fam... 75 2e-12
UniRef50_Q2LWN6 Cluster: NAD dependent epimerase/dehydratase fam... 75 2e-12
UniRef50_A7D7X9 Cluster: NAD-dependent epimerase/dehydratase; n=... 75 2e-12
UniRef50_UPI00015BAE89 Cluster: NAD-dependent epimerase/dehydrat... 73 6e-12
UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5; Halobacte... 73 6e-12
UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11
UniRef50_A1IA72 Cluster: Putative UDP-glucose-4-epimerase precur... 72 1e-11
UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=... 71 2e-11
UniRef50_Q8KWC8 Cluster: RB114; n=5; Proteobacteria|Rep: RB114 -... 71 3e-11
UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=... 71 3e-11
UniRef50_A4F9Y4 Cluster: UDP-glucose 4-epimerase; n=1; Saccharop... 70 4e-11
UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=... 69 8e-11
UniRef50_Q9UXJ4 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Sulf... 69 1e-10
UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;... 68 2e-10
UniRef50_A5GEM5 Cluster: NAD-dependent epimerase/dehydratase; n=... 68 2e-10
UniRef50_Q41C61 Cluster: NAD-dependent epimerase/dehydratase pre... 67 4e-10
UniRef50_Q07KU6 Cluster: NAD-dependent epimerase/dehydratase pre... 67 4e-10
UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2; Lactobaci... 66 5e-10
UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase fam... 66 5e-10
UniRef50_Q7V972 Cluster: Possible UDP-glucose-4-epimerase; n=1; ... 66 5e-10
UniRef50_Q0YI68 Cluster: NAD-dependent epimerase/dehydratase:Sho... 66 5e-10
UniRef50_A1BC39 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 7e-10
UniRef50_Q8YRD9 Cluster: Nucleotide sugar epimerase; n=6; Cyanob... 66 9e-10
UniRef50_Q04TJ8 Cluster: Glucose galactose epimerase; n=4; Lepto... 66 9e-10
UniRef50_A0L3Z4 Cluster: NAD-dependent epimerase/dehydratase; n=... 66 9e-10
UniRef50_Q1AWT4 Cluster: NAD-dependent epimerase/dehydratase; n=... 65 1e-09
UniRef50_Q0FS47 Cluster: UDP-glucose 4-epimerase; n=1; Roseovari... 65 1e-09
UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase pre... 65 1e-09
UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=... 65 1e-09
UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=... 65 2e-09
UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2; Halobac... 65 2e-09
UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=... 65 2e-09
UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase fam... 64 2e-09
UniRef50_O67354 Cluster: Nucleotide sugar epimerase; n=4; Bacter... 64 2e-09
UniRef50_Q01U23 Cluster: NAD-dependent epimerase/dehydratase; n=... 64 3e-09
UniRef50_Q5L1Q6 Cluster: NDP-sugar epimerase; n=6; Bacillaceae|R... 64 4e-09
UniRef50_A3PV39 Cluster: NAD-dependent epimerase/dehydratase pre... 64 4e-09
UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucl... 64 4e-09
UniRef50_Q8U032 Cluster: NDP-sugar dehydratase or epimerase; n=5... 64 4e-09
UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;... 63 7e-09
UniRef50_Q3E561 Cluster: NAD-dependent epimerase/dehydratase:Sho... 62 9e-09
UniRef50_A4MIF2 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 9e-09
UniRef50_A0A003 Cluster: MoeE5; n=1; Streptomyces ghanaensis|Rep... 62 9e-09
UniRef50_Q1AYI6 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 1e-08
UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1; Geobac... 62 2e-08
UniRef50_Q4E8F1 Cluster: NAD-dependent epimerase/dehydratase fam... 62 2e-08
UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytopha... 62 2e-08
UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=... 62 2e-08
UniRef50_Q58455 Cluster: Uncharacterized protein MJ1055; n=4; ce... 61 2e-08
UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=... 61 3e-08
UniRef50_A7HFB5 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 4e-08
UniRef50_A0GDZ4 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 4e-08
UniRef50_A0FYZ6 Cluster: NAD-dependent epimerase/dehydratase; n=... 60 4e-08
UniRef50_UPI0000384B58 Cluster: COG0451: Nucleoside-diphosphate-... 60 5e-08
UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1; Symbiobac... 60 5e-08
UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 60 5e-08
UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=... 59 8e-08
UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1; Cyanop... 59 8e-08
UniRef50_Q1VKN8 Cluster: UDP-glucose 4-epimerase; n=1; Psychrofl... 59 1e-07
UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or 4-6-... 59 1e-07
UniRef50_Q316B8 Cluster: NAD-dependent epimerase/dehydratase fam... 58 1e-07
UniRef50_A1FN39 Cluster: NAD-dependent epimerase/dehydratase; n=... 58 1e-07
UniRef50_Q04973 Cluster: Vi polysaccharide biosynthesis protein ... 58 2e-07
UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1; Mesorhizo... 58 2e-07
UniRef50_Q2S4X1 Cluster: UDP-glucuronate 5'-epimerase; n=3; Bact... 58 2e-07
UniRef50_A4A6D1 Cluster: UDP-glucose 4-epimerase; n=1; Congregib... 58 2e-07
UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular... 57 3e-07
UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 57 3e-07
UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3; Meth... 57 3e-07
UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2; Euryarcha... 57 3e-07
UniRef50_Q2RPP2 Cluster: NAD-dependent epimerase/dehydratase; n=... 57 4e-07
UniRef50_Q7P6D7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 57 4e-07
UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=... 57 4e-07
UniRef50_Q7UTP9 Cluster: UDP-glucose 4-epimerase homolog; n=2; P... 56 6e-07
UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=... 56 8e-07
UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;... 56 1e-06
UniRef50_Q9S1L1 Cluster: SpcI; n=1; Streptomyces netropsis|Rep: ... 56 1e-06
UniRef50_A5D3C1 Cluster: Nucleoside-diphosphate-sugar epimerases... 56 1e-06
UniRef50_A3ZYG1 Cluster: Nucleotide sugar epimerase; n=1; Blasto... 56 1e-06
UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=... 56 1e-06
UniRef50_Q3JAZ5 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 1e-06
UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 55 1e-06
UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=... 55 2e-06
UniRef50_A3I4Y7 Cluster: Nucleoside-diphosphate-sugar epimerase ... 54 2e-06
UniRef50_A2BD24 Cluster: Fcd; n=1; Geobacillus tepidamans|Rep: F... 54 2e-06
UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40; Vi... 54 2e-06
UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 3e-06
UniRef50_Q9HL87 Cluster: Nucleotide sugar epimerase related prot... 54 3e-06
UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;... 54 4e-06
UniRef50_Q67G37 Cluster: Probable dTDP-4-keto-6-deoxyhexose redu... 54 4e-06
UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 54 4e-06
UniRef50_Q67RC7 Cluster: UDP-glucose 4-epimerase; n=1; Symbiobac... 53 5e-06
UniRef50_Q02BA7 Cluster: NAD-dependent epimerase/dehydratase pre... 53 5e-06
UniRef50_Q0YTU0 Cluster: NAD-dependent epimerase/dehydratase:3-b... 53 7e-06
UniRef50_A0JYE3 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 9e-06
UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellula... 52 1e-05
UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase fam... 52 1e-05
UniRef50_Q112T2 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 1e-05
UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 1e-05
UniRef50_UPI0000384B3D Cluster: COG0451: Nucleoside-diphosphate-... 52 2e-05
UniRef50_Q47GM1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 52 2e-05
UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase fam... 52 2e-05
UniRef50_Q3VNH5 Cluster: NAD-dependent epimerase/dehydratase pre... 52 2e-05
UniRef50_Q11EL9 Cluster: NAD-dependent epimerase/dehydratase; n=... 52 2e-05
UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3; c... 52 2e-05
UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-b... 51 2e-05
UniRef50_A3H793 Cluster: NAD-dependent epimerase/dehydratase; n=... 51 2e-05
UniRef50_Q8A826 Cluster: CDP-abequose synthase; n=1; Bacteroides... 51 3e-05
UniRef50_Q1AWM7 Cluster: NAD-dependent epimerase/dehydratase pre... 51 3e-05
UniRef50_Q0C421 Cluster: Putative GDP-6-deoxy-D-lyxo-4-hexulose ... 51 3e-05
UniRef50_Q8GJ79 Cluster: DTDP glucose-4,6-dehydrogenase; n=11; B... 50 4e-05
UniRef50_A6UU12 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 50 4e-05
UniRef50_Q3ANB2 Cluster: Putative sugar nucleotide epimerase/deh... 50 5e-05
UniRef50_Q012L1 Cluster: DTDP-glucose 4-6-dehydratase-like prote... 50 5e-05
UniRef50_Q5UXR1 Cluster: UDP-glucose 4-epimerase; n=2; Halobacte... 50 7e-05
UniRef50_P39630 Cluster: Spore coat polysaccharide biosynthesis ... 50 7e-05
UniRef50_Q31EZ4 Cluster: NAD-dependent epimerase/dehydratase fam... 49 9e-05
UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05
UniRef50_A5UZF7 Cluster: NAD-dependent epimerase/dehydratase; n=... 49 9e-05
UniRef50_Q2ITF6 Cluster: DTDP-glucose 4,6-dehydratase; n=6; Bact... 49 1e-04
UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus ... 49 1e-04
UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=... 49 1e-04
UniRef50_UPI0001597DB3 Cluster: SpsJ; n=1; Bacillus amyloliquefa... 48 2e-04
UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar ep... 48 2e-04
UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillu... 48 2e-04
UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 48 2e-04
UniRef50_A1RUM8 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 2e-04
UniRef50_Q11EM0 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 2e-04
UniRef50_A5UZ84 Cluster: NAD-dependent epimerase/dehydratase; n=... 48 2e-04
UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|R... 48 3e-04
UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A7TUR9 Cluster: Putative nucleoside-diphosphate-sugar e... 48 3e-04
UniRef50_Q97A85 Cluster: NDP-sugar epimerase; n=3; Thermoplasmat... 48 3e-04
UniRef50_Q9SYM5 Cluster: Probable rhamnose biosynthetic enzyme 1... 48 3e-04
UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63... 47 4e-04
UniRef50_Q84CM4 Cluster: Nucleotide sugar epimerase; n=4; Proteo... 47 4e-04
UniRef50_A4EVQ8 Cluster: NAD-dependent epimerase/dehydratase fam... 47 4e-04
UniRef50_A7D6Z2 Cluster: NAD-dependent epimerase/dehydratase; n=... 47 4e-04
UniRef50_P95780 Cluster: dTDP-glucose 4,6-dehydratase; n=123; Ba... 47 4e-04
UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 47 5e-04
UniRef50_Q2SJW4 Cluster: Nucleoside-diphosphate-sugar epimerase;... 47 5e-04
UniRef50_Q1VUM7 Cluster: UDP-glucose 4-epimerase; n=1; Psychrofl... 47 5e-04
UniRef50_Q97H47 Cluster: Nucleoside-diphosphate-sugar epimerase;... 46 6e-04
UniRef50_Q0EXU3 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 46 6e-04
UniRef50_A3S1P1 Cluster: Putative LPS biosynthesis related DNTP-... 46 6e-04
UniRef50_Q980W1 Cluster: UDP-glucose 4-epimerase; n=4; Sulfoloba... 46 6e-04
UniRef50_Q474T2 Cluster: NAD-dependent epimerase/dehydratase:3-b... 46 8e-04
UniRef50_Q0S8T5 Cluster: UDP-glucose 4-epimerase; n=25; Actinoba... 46 8e-04
UniRef50_A7UH60 Cluster: Putative epimerase/dehydratase; n=1; De... 46 8e-04
UniRef50_A6FPS1 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 8e-04
UniRef50_UPI0001597850 Cluster: hypothetical protein RBAM_031220... 46 0.001
UniRef50_Q93N67 Cluster: DTDP-glucose-4,6 dehydratase; n=9; Bact... 46 0.001
UniRef50_Q661H6 Cluster: Nucleotide sugar epimerase; n=3; Borrel... 46 0.001
UniRef50_Q319Q1 Cluster: UDP-glucose 4-epimerase; n=1; Prochloro... 46 0.001
UniRef50_Q21Z09 Cluster: NAD-dependent epimerase/dehydratase; n=... 46 0.001
UniRef50_A5UUD9 Cluster: NAD-dependent epimerase/dehydratase; n=... 45 0.001
UniRef50_A4CBV8 Cluster: NAD dependent epimerase/dehydratase fam... 45 0.001
UniRef50_Q67G46 Cluster: Diphospho-4-keto-2,3,6-trideoxyhexulose... 45 0.002
UniRef50_A6GE58 Cluster: NAD-dependent epimerase/dehydratase fam... 45 0.002
UniRef50_A6EMI0 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 45 0.002
UniRef50_Q3M7S7 Cluster: 3-beta hydroxysteroid dehydrogenase/iso... 44 0.002
UniRef50_Q1WTH1 Cluster: UDP-glucose 4-epimerase; n=1; Lactobaci... 44 0.002
UniRef50_A0LBM1 Cluster: NAD-dependent epimerase/dehydratase; n=... 44 0.002
UniRef50_UPI0000E87F7E Cluster: probable nucleoside-diphosphate-... 44 0.003
UniRef50_Q1GN57 Cluster: NAD-dependent epimerase/dehydratase; n=... 44 0.003
UniRef50_A7D6W0 Cluster: NAD-dependent epimerase/dehydratase; n=... 44 0.003
UniRef50_Q30V12 Cluster: UDP-glucose 4-epimerase precursor; n=1;... 44 0.004
UniRef50_Q1NXD3 Cluster: NAD-dependent epimerase/dehydratase:dTD... 43 0.006
UniRef50_Q1IKI6 Cluster: NAD-dependent epimerase/dehydratase; n=... 43 0.006
UniRef50_A6BHD4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_Q9LZI2 Cluster: DTDP-glucose 4-6-dehydratase homolog D1... 43 0.006
UniRef50_Q00TT7 Cluster: Nucleotide-sugar epimerase; n=2; Ostreo... 43 0.006
UniRef50_Q9YCT1 Cluster: DTDP-glucose 4,6-dehydratase; n=2; Ther... 43 0.006
UniRef50_Q7VFZ2 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 43 0.008
UniRef50_Q6E7F2 Cluster: Fcf1; n=1; Escherichia coli|Rep: Fcf1 -... 43 0.008
UniRef50_Q09SL2 Cluster: WbmG; n=3; Bordetella|Rep: WbmG - Borde... 43 0.008
UniRef50_Q07RG8 Cluster: DTDP-glucose 4,6-dehydratase precursor;... 43 0.008
UniRef50_A4QBQ2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.008
UniRef50_A4BEM6 Cluster: Probable nucleotide sugar dehydratase; ... 43 0.008
UniRef50_A0CMY0 Cluster: Chromosome undetermined scaffold_22, wh... 43 0.008
UniRef50_A7HIS5 Cluster: dTDP-glucose 4,6-dehydratase; n=5; cell... 42 0.010
UniRef50_Q9UXL5 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Sulf... 42 0.010
UniRef50_Q00329 Cluster: CDP-abequose synthase; n=1; Salmonella ... 42 0.010
UniRef50_Q7NIH7 Cluster: Gll2206 protein; n=14; Bacteria|Rep: Gl... 42 0.013
UniRef50_Q07IP9 Cluster: NAD-dependent epimerase/dehydratase pre... 42 0.013
UniRef50_Q5V4R9 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte... 42 0.013
UniRef50_Q5V3C6 Cluster: DTDP-glucose dehydratase; n=23; cellula... 42 0.013
UniRef50_Q18EM2 Cluster: Nucleoside-diphosphate-sugar epimerase;... 42 0.013
UniRef50_A6UU00 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.013
UniRef50_Q124Z2 Cluster: NAD-dependent epimerase/dehydratase; n=... 42 0.018
UniRef50_Q9RCC9 Cluster: CDP-paratose synthetase; n=10; Yersinia... 41 0.023
UniRef50_Q7WR33 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 41 0.023
UniRef50_Q6MDS0 Cluster: Putative dTDP-glucose 4,6-dehydratase, ... 41 0.023
UniRef50_Q2L330 Cluster: Putative sugar epimerase/dehydratase; n... 41 0.023
UniRef50_Q1IMR1 Cluster: NAD-dependent epimerase/dehydratase; n=... 41 0.023
UniRef50_A0LKC0 Cluster: NAD-dependent epimerase/dehydratase; n=... 41 0.023
UniRef50_Q9WZ98 Cluster: Nucleotide sugar epimerase, putative; n... 41 0.031
UniRef50_Q1MNV8 Cluster: Nucleoside-diphosphate-sugar epimerases... 41 0.031
UniRef50_A5V0L7 Cluster: NAD-dependent epimerase/dehydratase; n=... 41 0.031
UniRef50_Q5UXR0 Cluster: UDP-glucose 4-epimerase; n=3; Halobacte... 41 0.031
UniRef50_P29782 Cluster: dTDP-glucose 4,6-dehydratase; n=65; Bac... 41 0.031
UniRef50_O54067 Cluster: UDP-glucuronate 5'-epimerase; n=163; ce... 41 0.031
UniRef50_Q8YBQ8 Cluster: UDP-GLUCOSE 4-EPIMERASE; n=15; Bacteria... 40 0.041
UniRef50_Q0EYJ2 Cluster: NAD dependent epimerase/dehydratase fam... 40 0.041
UniRef50_Q8ZW82 Cluster: UDP-glucose 4-epimerase; n=6; Thermopro... 40 0.041
UniRef50_Q0W7F9 Cluster: Putative UDP-glucose 4-epimerase; n=1; ... 40 0.041
UniRef50_Q28JF0 Cluster: NAD-dependent epimerase/dehydratase; n=... 40 0.054
UniRef50_Q0LQ90 Cluster: NAD-dependent epimerase/dehydratase; n=... 40 0.054
UniRef50_A7FQ16 Cluster: NAD-dependent epimerase/dehydratase fam... 40 0.054
UniRef50_Q97XJ9 Cluster: DTDP-Glucose 4,6-dehydratase; n=2; Sulf... 40 0.054
UniRef50_Q7VZF5 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 40 0.054
UniRef50_Q81AP5 Cluster: CDP-abequose synthase; n=2; Bacillus ce... 40 0.071
UniRef50_Q84I27 Cluster: Truncated nucleotide-sugar epimerase; n... 40 0.071
UniRef50_Q0K7P9 Cluster: NAD dependent sugar epimerase; n=3; Pro... 40 0.071
UniRef50_Q09SL1 Cluster: WbmF; n=3; Bordetella|Rep: WbmF - Borde... 40 0.071
UniRef50_A7HYG9 Cluster: NAD-dependent epimerase/dehydratase pre... 40 0.071
UniRef50_A3BNC3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.071
UniRef50_Q9RZB3 Cluster: Thymidine diphosphoglucose 4,6-dehydrat... 39 0.094
UniRef50_Q8F9G0 Cluster: DTDP-glucose 4,6-dehydratase; n=4; Lept... 39 0.094
UniRef50_Q2JDH1 Cluster: NAD-dependent epimerase/dehydratase; n=... 39 0.094
UniRef50_Q7WT21 Cluster: NDP-4-keto-6-deoxyhexose reductase; n=1... 39 0.094
UniRef50_Q4R0L7 Cluster: ChaS4 protein; n=1; Streptomyces chartr... 39 0.094
UniRef50_Q2MFI4 Cluster: Putative apramycin biosynthetic oxidore... 39 0.094
UniRef50_Q1VK02 Cluster: Sugar epimerase BlmG; n=1; Psychroflexu... 39 0.094
UniRef50_Q0FE84 Cluster: UDP-glucose 4-epimerase; n=1; alpha pro... 39 0.094
UniRef50_A5GIA6 Cluster: NAD dependent epimerase/dehydratase; n=... 39 0.094
UniRef50_A4J5R3 Cluster: NAD-dependent epimerase/dehydratase; n=... 39 0.094
UniRef50_A3SGX4 Cluster: Putative epimerase/dehydratase; n=1; Su... 39 0.094
UniRef50_A1IA75 Cluster: CDP-tyvelose-2-epimerase; n=4; Bacteria... 39 0.094
UniRef50_Q9L4S7 Cluster: NDP-hexose 4-ketoreductase UrdZ3; n=3; ... 39 0.12
UniRef50_Q1ILI4 Cluster: NAD-dependent epimerase/dehydratase pre... 39 0.12
UniRef50_A6GG02 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_A5V019 Cluster: NAD-dependent epimerase/dehydratase; n=... 39 0.12
UniRef50_A1ZEA9 Cluster: NAD-dependent epimerase/dehydratase; n=... 39 0.12
UniRef50_Q64W39 Cluster: Putative dTDP-glucose 4,6-dehydratase; ... 38 0.16
UniRef50_Q3A2B7 Cluster: Nucleoside-diphosphate-sugar epimerases... 38 0.16
UniRef50_Q2RKH0 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.16
UniRef50_A5ZJJ7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.16
UniRef50_P14168 Cluster: Paratose synthase; n=7; Salmonella|Rep:... 38 0.16
UniRef50_O49213 Cluster: GDP-L-fucose synthase 1; n=181; root|Re... 38 0.16
UniRef50_Q89HI4 Cluster: GalE protein; n=4; Bacteria|Rep: GalE p... 38 0.22
UniRef50_Q3B1R9 Cluster: GDP-L-fucose synthetase; n=3; Bacteria|... 38 0.22
UniRef50_Q6T1X6 Cluster: GDP-6-deoxy-D-lyxo-4-hexulose reductase... 38 0.22
UniRef50_Q124Z8 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.22
UniRef50_A6TTQ2 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.22
UniRef50_A4LY98 Cluster: NAD-dependent epimerase/dehydratase pre... 38 0.22
UniRef50_A3ERK1 Cluster: Nucleoside-diphosphate-sugar epimerase;... 38 0.22
UniRef50_UPI0000382708 Cluster: COG0451: Nucleoside-diphosphate-... 38 0.29
UniRef50_Q893U9 Cluster: NDP-sugar dehydratase or epimerase; n=1... 38 0.29
UniRef50_Q6MHK5 Cluster: ADP-L-glycero-D-mannoheptose-6-epimeras... 38 0.29
UniRef50_Q6AGL6 Cluster: UDP-glucose 4-epimerase; n=1; Leifsonia... 38 0.29
UniRef50_Q2JGH9 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.29
UniRef50_Q0LHP2 Cluster: NAD-dependent epimerase/dehydratase; n=... 38 0.29
UniRef50_O54256 Cluster: SnogG; n=4; Streptomyces|Rep: SnogG - S... 38 0.29
UniRef50_A0NNU7 Cluster: Nucleoside-diphosphate-sugar epimerase;... 38 0.29
UniRef50_Q97CP3 Cluster: NDP-sugar epimerase; n=4; Thermoplasmat... 38 0.29
UniRef50_Q93VR3 Cluster: GDP-mannose 3,5-epimerase; n=21; cellul... 38 0.29
UniRef50_UPI000023CA7E Cluster: hypothetical protein FG02355.1; ... 37 0.38
UniRef50_A5C3L4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.38
UniRef50_Q18EM3 Cluster: Nucleoside-diphosphate-sugar epimerase;... 37 0.38
UniRef50_Q8X7P7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=... 37 0.38
UniRef50_Q8DJM2 Cluster: Nucleotide sugar epimerase; n=61; cellu... 37 0.50
UniRef50_Q7V0Q5 Cluster: Putative CDP-tyvelose-2-epimerase; n=1;... 37 0.50
UniRef50_Q5M6T3 Cluster: Nucleotidyl-sugar dehydratase; n=2; Cam... 37 0.50
UniRef50_Q1IJY8 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 37 0.50
UniRef50_Q0LJD8 Cluster: DTDP-glucose 4,6-dehydratase; n=1; Herp... 37 0.50
UniRef50_Q018E1 Cluster: GDP-mannose 4,6 dehydratase; n=1; Ostre... 37 0.50
UniRef50_Q01T66 Cluster: DTDP-glucose 4,6-dehydratase precursor;... 36 0.66
UniRef50_A6QAJ4 Cluster: dTDP-glucose 4,6-dehydratase; n=1; Sulf... 36 0.66
UniRef50_A6PTN5 Cluster: NAD-dependent epimerase/dehydratase pre... 36 0.66
UniRef50_A3PTJ5 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 0.66
UniRef50_Q8UJL3 Cluster: UDP-glucose 4-epimerase; n=3; Rhizobiac... 36 0.87
UniRef50_Q2S4X2 Cluster: Sugar epimerase BlmG; n=2; Bacteroidete... 36 0.87
UniRef50_A6G7N0 Cluster: Oxidoreductase, short chain dehydrogena... 36 0.87
UniRef50_A1SL10 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 0.87
UniRef50_Q9HRD1 Cluster: UDP-glucose 4-epimerase; n=6; Euryarcha... 36 0.87
UniRef50_Q57103 Cluster: CDP-3, 6-dideoxy-D-glycero-L-glycero-4-... 36 1.2
UniRef50_Q3VUK6 Cluster: TPR repeat; n=1; Prosthecochloris aestu... 36 1.2
UniRef50_Q2IZX2 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.2
UniRef50_O66157 Cluster: Deduced dNDP-hexose 4,6-dehydratase; n=... 36 1.2
UniRef50_A5FSS2 Cluster: NAD-dependent epimerase/dehydratase; n=... 36 1.2
UniRef50_A0QWJ7 Cluster: Major facilitator family protein transp... 36 1.2
UniRef50_Q55549 Cluster: Slr0168 protein; n=1; Synechocystis sp.... 35 1.5
UniRef50_Q2LWP6 Cluster: CDP-4-dehydro-6-deoxy-D-gulose 4-reduct... 35 1.5
UniRef50_Q4AJ59 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 1.5
UniRef50_Q1QSK3 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 1.5
UniRef50_A7CZR0 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 35 1.5
UniRef50_A2BSE2 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5
UniRef50_Q94JQ5 Cluster: AT5g59290/mnc17_180; n=179; cellular or... 35 1.5
UniRef50_UPI00004DB9FC Cluster: UPI00004DB9FC related cluster; n... 35 2.0
UniRef50_Q8YRM2 Cluster: GDP-mannose 4,6-dehydratase; n=2; Nosto... 35 2.0
UniRef50_Q6MMG6 Cluster: CDP-D-glucose-4,6-dehydratase; n=1; Bde... 35 2.0
UniRef50_Q2IHK2 Cluster: NAD-dependent epimerase/dehydratase pre... 35 2.0
UniRef50_A7HFB6 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 2.0
UniRef50_A4XRB8 Cluster: NAD-dependent epimerase/dehydratase pre... 35 2.0
UniRef50_A3ZNV0 Cluster: Nucleoside-diphosphate-sugar epimerase;... 35 2.0
UniRef50_A0TAK5 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 2.0
UniRef50_A2GEF2 Cluster: NAD dependent epimerase/dehydratase fam... 35 2.0
UniRef50_Q0UY12 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_Q8PRA9 Cluster: Degenerated UDP-glucose epimerase; n=1;... 34 2.7
UniRef50_Q0C425 Cluster: DTDP-glucose 4,6-dehydratase; n=4; Prot... 34 2.7
UniRef50_A4WZQ1 Cluster: Putative uncharacterized protein precur... 34 2.7
UniRef50_A0UW76 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 2.7
UniRef50_Q8NBZ7 Cluster: UDP-glucuronic acid decarboxylase 1; n=... 34 2.7
UniRef50_Q1VUQ5 Cluster: Sugar epimerase BlmG; n=2; Bacteria|Rep... 34 3.5
UniRef50_A6G1I8 Cluster: GalE2; n=1; Plesiocystis pacifica SIR-1... 34 3.5
UniRef50_A4WAA3 Cluster: NAD-dependent epimerase/dehydratase; n=... 34 3.5
UniRef50_A0ZLV6 Cluster: Probable CDP-tyvelose epimerase; n=3; B... 34 3.5
UniRef50_A2Y3J1 Cluster: Putative uncharacterized protein; n=1; ... 34 3.5
UniRef50_Q72ET7 Cluster: ADP-L-glycero-D-manno-heptose-6-epimera... 34 3.5
UniRef50_Q54366 Cluster: LmbM protein; n=1; Streptomyces lincoln... 33 4.7
UniRef50_Q1GGJ8 Cluster: NAD-dependent epimerase/dehydratase; n=... 33 4.7
UniRef50_Q111Y7 Cluster: Protein splicing site; n=2; cellular or... 33 4.7
UniRef50_A7GLV8 Cluster: CDP-glucose 4,6-dehydratase; n=5; Bacil... 33 4.7
UniRef50_A6WFW4 Cluster: NAD-dependent epimerase/dehydratase pre... 33 4.7
UniRef50_A3ZSY1 Cluster: CDP-abequose synthase; n=1; Blastopirel... 33 4.7
UniRef50_A2BW10 Cluster: Possible nucleoside-diphosphate-sugar e... 33 4.7
UniRef50_Q19003 Cluster: Squashed vulva protein 1; n=4; cellular... 33 4.7
UniRef50_A7DQT2 Cluster: NAD-dependent epimerase/dehydratase; n=... 33 4.7
UniRef50_Q8KBD7 Cluster: Partitioning protein, ParB family; n=10... 33 6.2
UniRef50_Q47PG2 Cluster: UDP-glucose 4-epimerase; n=1; Thermobif... 33 6.2
UniRef50_Q9FB21 Cluster: Sugar epimerase BlmG; n=1; Streptomyces... 33 6.2
UniRef50_Q1QD53 Cluster: NAD-dependent epimerase/dehydratase; n=... 33 6.2
UniRef50_Q0LJ11 Cluster: NAD-dependent epimerase/dehydratase; n=... 33 6.2
UniRef50_A3VAM5 Cluster: Probable UDPglucose 4-epimerase; n=1; R... 33 6.2
UniRef50_Q012R4 Cluster: Putative nucleotide sugar epimerase; n=... 33 6.2
UniRef50_Q7R737 Cluster: NAD dependent epimerase/dehydratase fam... 33 6.2
UniRef50_Q9PYZ5 Cluster: ORF48; n=1; Xestia c-nigrum granuloviru... 33 8.1
UniRef50_Q64WT2 Cluster: Sensor protein; n=3; Bacteroides|Rep: S... 33 8.1
UniRef50_Q4HQ86 Cluster: UDP-glucose 4-epimerase, putative; n=2;... 33 8.1
UniRef50_Q08Z97 Cluster: Putative mRNA-binding protein; n=1; Sti... 33 8.1
UniRef50_A5G621 Cluster: Ricin B lectin; n=1; Geobacter uraniumr... 33 8.1
UniRef50_A3ZRJ8 Cluster: Oxidoreductase; n=1; Blastopirellula ma... 33 8.1
>UniRef50_Q14376 Cluster: UDP-glucose 4-epimerase; n=150; cellular
organisms|Rep: UDP-glucose 4-epimerase - Homo sapiens
(Human)
Length = 348
Score = 282 bits (691), Expect = 6e-75
Identities = 123/219 (56%), Positives = 160/219 (73%), Gaps = 1/219 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG P++LP+ E HPTG TN YG++K+FIEEM++DL AD WN + LRYF
Sbjct: 127 LVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYF 186
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP GAH SG IGEDP NLMP+++QVA+G++ L VFG DY+T DGTG+RDYIHV+D
Sbjct: 187 NPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVD 246
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA GH+AAL L + ++YNLGTG G SV ++V E+ + K+P K V RR GD++
Sbjct: 247 LAKGHIAALRKLKE-QCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVA 305
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
A +A+ SLA+EELGW+ L ++ MC D WRWQ NP G+
Sbjct: 306 ACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGF 344
>UniRef50_Q9T0A7 Cluster: Probable UDP-glucose 4-epimerase
At4g23920; n=58; cellular organisms|Rep: Probable
UDP-glucose 4-epimerase At4g23920 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 350
Score = 271 bits (665), Expect = 9e-72
Identities = 127/219 (57%), Positives = 152/219 (69%), Gaps = 1/219 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG P+ +P TE P S TN YGRTK FIEE+ +D+ +D +W II LRYF
Sbjct: 124 LVFSSSATVYGWPKEVPCTEESPI-SATNPYGRTKLFIEEICRDVHRSDSEWKIILLRYF 182
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAHPSG IGEDP NLMP++ QVA+G++P LTVFGTDY T DGTG+RDYIHVMD
Sbjct: 183 NPVGAHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTGVRDYIHVMD 242
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA GH+AAL L I +VYNLGTG G SV E+V FE+ + K+PL RR GD
Sbjct: 243 LADGHIAALRKLDDLKISCEVYNLGTGNGTSVLEMVAAFEKASGKKIPLVMAGRRPGDAE 302
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
++A T A+ EL W + IEEMC D W W + NP GY
Sbjct: 303 VVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYGY 341
>UniRef50_O54385 Cluster: UDP-glucose epimerase; n=11; cellular
organisms|Rep: UDP-glucose epimerase - Brucella abortus
Length = 335
Score = 252 bits (617), Expect = 6e-66
Identities = 118/219 (53%), Positives = 151/219 (68%), Gaps = 3/219 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG+P+ LPITE P S TN YGRTK IE+ML+DL +D+ W I LRYF
Sbjct: 119 LVFSSSATVYGDPDKLPITEDQPL-SATNPYGRTKLVIEDMLRDLYNSDNSWAIAILRYF 177
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAH SGLIGEDP NLMP +AQVA G++ L ++G DY TPDGTG+RDYIHV D
Sbjct: 178 NPVGAHESGLIGEDPKGIPNNLMPIIAQVATGRREKLNIWGNDYPTPDGTGVRDYIHVND 237
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA+GH+ AL L + + NLGTG+G SV +++ FE V+ ++ + RR GD++
Sbjct: 238 LAAGHLKALKKLDKP--KCFAVNLGTGQGYSVLDVIKAFEHVSNREIKYEIAPRRPGDVA 295
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
+AD AK+ LGWS + + EMC D W WQ+ NP+GY
Sbjct: 296 ECYADPGFAKKFLGWSAEKNLREMCQDMWNWQSKNPNGY 334
>UniRef50_Q42605 Cluster: UDP-glucose 4-epimerase; n=20;
Viridiplantae|Rep: UDP-glucose 4-epimerase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 351
Score = 252 bits (616), Expect = 7e-66
Identities = 118/223 (52%), Positives = 152/223 (68%), Gaps = 2/223 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
MVFSSS TVYG+PE +P E ++ N YGRTK F+EE+ +D+ A+ +W II LRYF
Sbjct: 129 MVFSSSATVYGQPEKIPCMEDFELKAM-NPYGRTKLFLEEIARDIQKAEPEWRIILLRYF 187
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAH SG IGEDP NLMP++ QVA+G+ P L V+G DY T DG+ +RDYIHVMD
Sbjct: 188 NPVGAHESGSIGEDPKGIPNNLMPYIQQVAVGRLPELNVYGHDYPTEDGSAVRDYIHVMD 247
Query: 121 LASGHVAAL-NLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
LA GH+AAL L + I YNLGTG+G SV E+V FE+ + K+P+K RR GD
Sbjct: 248 LADGHIAALRKLFADPKIGCTAYNLGTGQGTSVLEMVAAFEKASGKKIPIKLCPRRSGDA 307
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKK 222
+A++A T A++ELGW + ++EMC D W+W NP GY K
Sbjct: 308 TAVYASTEKAEKELGWKAKYGVDEMCRDQWKWANNNPWGYQNK 350
>UniRef50_P18645 Cluster: UDP-glucose 4-epimerase; n=353; cellular
organisms|Rep: UDP-glucose 4-epimerase - Rattus
norvegicus (Rat)
Length = 347
Score = 244 bits (598), Expect = 1e-63
Identities = 115/219 (52%), Positives = 150/219 (68%), Gaps = 4/219 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTG-SITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+VFSSS TVYG+P +P + P T YG++K+FIEEM++DL AD WN + LRY
Sbjct: 127 LVFSSSATVYGKP--VPASGRGPPHRGCTKPYGKSKFFIEEMIQDLCRADTAWNAVLLRY 184
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
F P+GAH S IGEDP NLMP+++QVA+G++ L VFG DY T DGTG+RDYIHV+
Sbjct: 185 FIPIGAHRSARIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATEDGTGVRDYIHVV 244
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA GH+AAL L + ++YNLGTG G SV ++V E+ + K+P K V RR GD+
Sbjct: 245 DLAKGHIAALKKLKE-QCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDV 303
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDG 218
+A +A+ SLA EELGW+ L ++ MC D WRWQ NP G
Sbjct: 304 AACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSG 342
>UniRef50_Q8H931 Cluster: Putative UDP-glucose 4-epimerase; n=5;
Oryza sativa|Rep: Putative UDP-glucose 4-epimerase -
Oryza sativa subsp. japonica (Rice)
Length = 408
Score = 241 bits (591), Expect = 8e-63
Identities = 112/220 (50%), Positives = 148/220 (67%), Gaps = 2/220 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS VYG P++ P TE P + N YG+TK +E++ +D+ D +W II LRYF
Sbjct: 133 LVFSSSAAVYGSPKNSPWTEEFPL-TPNNPYGKTKLVVEDICRDIYRTDPEWKIILLRYF 191
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAHPSG +GEDP NLMP++ QVA+G++P LT+ G DY T DGTG+RDYIHV+D
Sbjct: 192 NPVGAHPSGYLGEDPCGIPNNLMPYVQQVAVGRRPALTILGNDYATRDGTGVRDYIHVVD 251
Query: 121 LASGHVAAL-NLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
LA GH+AAL L + I + YNLGTGKG SV E+V FE+ + K+PL RR GD
Sbjct: 252 LADGHIAALQKLFESSSIGCEAYNLGTGKGTSVLEIVKAFEKASGKKIPLIIGPRRPGDA 311
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
+++ + A++EL W + I+EMC D W W + NP GY
Sbjct: 312 EILFSLPAKAEKELNWKAKFGIDEMCRDQWNWASKNPYGY 351
>UniRef50_UPI0000DAE763 Cluster: hypothetical protein
Rgryl_01001156; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001156 - Rickettsiella
grylli
Length = 341
Score = 236 bits (577), Expect = 4e-61
Identities = 109/219 (49%), Positives = 144/219 (65%), Gaps = 1/219 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSS VYGEP+ +PI E P I N Y R+K +E +L DL A+ W+I+ LRYF
Sbjct: 121 LIFSSSAAVYGEPKCVPIRENFPLSPI-NPYARSKLMVENILTDLHHAEPDWHIVCLRYF 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAH SGLIGEDP K NLMP+L QVA+G+ +FG +Y T DGT IRDYIHVMD
Sbjct: 180 NPVGAHESGLIGEDPKKFTHNLMPYLTQVAIGRSKQFNIFGGNYPTVDGTAIRDYIHVMD 239
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA GHVAAL+ + + NL TGKG+SV E++ F + K+ + +DRR GD++
Sbjct: 240 LAEGHVAALSNYTNWKRGVLTVNLSTGKGLSVLEVLRAFTEFNQCKIAYRILDRRPGDVA 299
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
WAD + A+ L W + ++ ++C D WRWQ NP+GY
Sbjct: 300 ECWADPTNAQRILNWKARRSLAQICKDSWRWQKANPNGY 338
>UniRef50_Q0IDK5 Cluster: UDP-glucose 4-epimerase; n=3;
Cyanobacteria|Rep: UDP-glucose 4-epimerase -
Synechococcus sp. (strain CC9311)
Length = 370
Score = 226 bits (552), Expect = 4e-58
Identities = 112/233 (48%), Positives = 145/233 (62%), Gaps = 11/233 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDK--------- 51
+VFSSS T+YG P+ +PI ET P I N YG +K E + D++ K
Sbjct: 139 LVFSSSATLYGYPDQVPIPETAPIQPI-NPYGASKQAAEALFADIAGCSGKPEPIQASQG 197
Query: 52 -WNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGT 110
W I LRYFNPVGAHPSG IGEDP NL PF+ QVA+G++P LTVFG D+ TPDGT
Sbjct: 198 GWRIARLRYFNPVGAHPSGRIGEDPNGIPNNLFPFITQVAIGRRPELTVFGDDWPTPDGT 257
Query: 111 GIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLK 170
G+RDYIHVMDLA GH AL+ L T +L NLG+G+G SV ++V E ++ +P +
Sbjct: 258 GVRDYIHVMDLAEGHREALHSLLNTDPQLLTLNLGSGQGASVLDVVKAMEAASQRAIPYR 317
Query: 171 YVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKKT 223
RR GD + A+ +LA + L W TQ ++ E+C D W WQ NP GY ++T
Sbjct: 318 IAPRRPGDAALTVANPTLAAQHLHWRTQRSLAEICRDGWAWQQANPQGYIRQT 370
>UniRef50_P04397 Cluster: Bifunctional protein GAL10 [Includes:
UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase);
Aldose 1-epimerase (EC 5.1.3.3) (Mutarotase)]; n=187;
cellular organisms|Rep: Bifunctional protein GAL10
[Includes: UDP-glucose 4-epimerase (EC 5.1.3.2)
(Galactowaldenase); Aldose 1-epimerase (EC 5.1.3.3)
(Mutarotase)] - Saccharomyces cerevisiae (Baker's yeast)
Length = 699
Score = 224 bits (548), Expect = 1e-57
Identities = 113/226 (50%), Positives = 146/226 (64%), Gaps = 9/226 (3%)
Query: 2 VFSSSCTVYGE----PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDK-WNIIS 56
VFSSS TVYG+ P +PI E P G TN YG TKY IE +L DL +D K W
Sbjct: 131 VFSSSATVYGDATRFPNMIPIPEECPLGP-TNPYGHTKYAIENILNDLYNSDKKSWKFAI 189
Query: 57 LRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYI 116
LRYFNP+GAHPSGLIGEDP NL+P++AQVA+G++ L +FG DY++ DGT IRDYI
Sbjct: 190 LRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDYI 249
Query: 117 HVMDLASGHVAALNLL---SQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVD 173
HV+DLA GH+AAL L ++ + +NLG+GKG +V E+ + F + + +P K
Sbjct: 250 HVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTG 309
Query: 174 RRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
RR GD+ + A AK EL W T+L +E+ C D W+W T NP GY
Sbjct: 310 RRAGDVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTENPFGY 355
>UniRef50_A5GHV3 Cluster: UDP-glucose-4-epimerase; n=11;
Cyanobacteria|Rep: UDP-glucose-4-epimerase -
Synechococcus sp. (strain WH7803)
Length = 351
Score = 223 bits (545), Expect = 3e-57
Identities = 109/219 (49%), Positives = 140/219 (63%), Gaps = 1/219 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSSCTVYG + I E I N YGRTK +E+ML D +D +W I LRYF
Sbjct: 126 LVFSSSCTVYGTSKQKKINEASTIAPI-NPYGRTKAAVEQMLLDQFNSDPQWRICCLRYF 184
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NPVGAHPSG IGEDP NL PFL QVA ++ L +FG D+ T DGT IRDYIH++D
Sbjct: 185 NPVGAHPSGHIGEDPKGTPGNLFPFLMQVAKKQRKKLNIFGNDWPTADGTCIRDYIHILD 244
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
L GH+AAL L + + NLGTG GVSV E V+ FE+ T VP ++V+RR GD +
Sbjct: 245 LVDGHLAALRFLCEEAPQWLAVNLGTGIGVSVLEFVSAFEQATGLVVPYEFVERRAGDAA 304
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
AD S+A ++L W ++ ++C D W+WQ NP+G+
Sbjct: 305 VAVADPSVALKKLKWKPVRSLRDICIDGWKWQNANPNGF 343
>UniRef50_A5M424 Cluster: UDP-glucose 4-epimerase; n=1;
Streptococcus pneumoniae SP11-BS70|Rep: UDP-glucose
4-epimerase - Streptococcus pneumoniae SP11-BS70
Length = 342
Score = 223 bits (544), Expect = 4e-57
Identities = 109/219 (49%), Positives = 142/219 (64%), Gaps = 2/219 (0%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSSS TVY +P ET+P + +N YGRTK +IE +L DL ++ W I+ LRYFN
Sbjct: 123 VFSSSATVYESTPIMPFYETNPLKA-SNPYGRTKQYIEVLLNDLFISNSNWKIVCLRYFN 181
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
P+GAH SG +GEDP NL+P++ QVA+GK P L +FG DY+TPDGT IRDY+HV DL
Sbjct: 182 PLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLNIFGVDYSTPDGTCIRDYVHVNDL 241
Query: 122 ASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
A GH AL + T L +V NLG+G G SV E+++ E V + +P K RR GD+
Sbjct: 242 AYGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEILHSLESVIGSYIPYKITSRRAGDMD 301
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
AD S A+E LGW + I +MC D W+WQ +P+GY
Sbjct: 302 VSIADISKAEELLGWKPRYDIMKMCQDTWKWQQKHPNGY 340
>UniRef50_Q7VAY9 Cluster: UDP-glucose 4-epimerase; n=2;
Prochlorococcus marinus|Rep: UDP-glucose 4-epimerase -
Prochlorococcus marinus
Length = 347
Score = 219 bits (536), Expect = 4e-56
Identities = 108/223 (48%), Positives = 141/223 (63%), Gaps = 2/223 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLS-AADDKWNIISLRY 59
+VFSSS T+YG + +PI E I N YG +K +E++L DLS +A W I LRY
Sbjct: 126 IVFSSSATIYGNTDKVPIKEDSLISPI-NPYGESKATVEKILSDLSLSAPFDWRIACLRY 184
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FNPVGAHPSG IGEDP NL P++ VA G+ + VFG D+ T DGTG+RDY+HV+
Sbjct: 185 FNPVGAHPSGRIGEDPLGIPNNLFPYITNVAGGQIKQVEVFGNDWPTQDGTGVRDYVHVL 244
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA H +AL L +L + NLG G G+SV E++N F RV +VP + RR GDI
Sbjct: 245 DLAEAHKSALECLFAEPAQLLILNLGNGFGLSVLEIINTFSRVNNCEVPYVFAARRPGDI 304
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKK 222
+ +AD +L+K L W + +IE+MC D WRW+ NP GY K
Sbjct: 305 AISYADIALSKARLNWYPKRSIEDMCRDTWRWKLNNPIGYRSK 347
>UniRef50_Q7MX67 Cluster: UDP-glucose 4-epimerase; n=12;
Bacteroidetes|Rep: UDP-glucose 4-epimerase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 342
Score = 218 bits (533), Expect = 9e-56
Identities = 107/215 (49%), Positives = 139/215 (64%), Gaps = 3/215 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSSCTVYG+PE LP+TE P + YG TK EE+++D A + I LRYF
Sbjct: 122 IVFSSSCTVYGQPEVLPVTEEAPIQEALSPYGNTKQINEEIIRDAIHAGAGYKAILLRYF 181
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP+GAHP+ IGE P NL+P+L Q A G + L+VFG DY+TPDG+ IRDYI+V+D
Sbjct: 182 NPIGAHPTAHIGELPNGVPQNLIPYLTQTAAGIRAELSVFGDDYDTPDGSCIRDYIYVVD 241
Query: 121 LASGHVAALNLL---SQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
LA HVAA+ + + L+V+N+GTG+GVSV EL+ FERVT VP + V RR G
Sbjct: 242 LAKAHVAAIERMLNEEKASDSLEVFNIGTGRGVSVLELIRTFERVTGVAVPHRIVGRREG 301
Query: 178 DISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
DI +WA+ A E LGW ++E+ WRWQ
Sbjct: 302 DIEQVWAEPKKANEVLGWKALESLEDTLLSAWRWQ 336
>UniRef50_A6RJ24 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 436
Score = 215 bits (526), Expect = 6e-55
Identities = 107/217 (49%), Positives = 142/217 (65%), Gaps = 8/217 (3%)
Query: 1 MVFSSSCTVYGEPEH--LPITETHPTGS----ITNVYGRTKYFIEEMLKDLSAADDKWNI 54
MVFSSS TVYG +P+ E + GS +TN YGRTK+ E +L DL+ +D W I
Sbjct: 210 MVFSSSATVYGTVADTGVPLREEYVVGSGCSGLTNPYGRTKWMCEAILSDLANSDPDWEI 269
Query: 55 ISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRD 114
+LRYFNP+G SGL+GEDP TNLMP + +V G P L V+G+DY+T DGT +RD
Sbjct: 270 TALRYFNPIGCDESGLLGEDPRAAATNLMPVVLRVLTGALPALNVYGSDYDTHDGTAVRD 329
Query: 115 YIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDR 174
YIHV DLA GH+AAL+ ++ KVYNLGTG+G SV ++VN E+ T+ K+P V R
Sbjct: 330 YIHVTDLARGHLAALS--NRPSGGFKVYNLGTGQGYSVLDVVNAMEKATQTKIPTNIVGR 387
Query: 175 RLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
R GD+ A + A+EEL W T+ ++E+ C D WR+
Sbjct: 388 RGGDVGKCVALANKAEEELMWKTEKSLEDCCNDLWRF 424
>UniRef50_A1ZWK4 Cluster: UDP-glucose 4-epimerase; n=16;
Bacteroidetes|Rep: UDP-glucose 4-epimerase - Microscilla
marina ATCC 23134
Length = 351
Score = 213 bits (520), Expect = 3e-54
Identities = 109/221 (49%), Positives = 137/221 (61%), Gaps = 9/221 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAAD------DKWNI 54
+VFSSSCTVYG+P LP+TET + YG TK EE++KD A++ N
Sbjct: 120 LVFSSSCTVYGQPATLPVTETAAVVPAASPYGNTKQVCEEIIKDTVASNVLNPEQSAMNA 179
Query: 55 ISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRD 114
+ LRYFNP+GAHPSG IGE P NL+PF+ Q A G +P LTVFG DYNTPDGT IRD
Sbjct: 180 VLLRYFNPIGAHPSGQIGELPLGVPGNLVPFITQTAAGIRPQLTVFGNDYNTPDGTCIRD 239
Query: 115 YIHVMDLASGHVAALNLLSQTHIR---LKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY 171
YIHV+DLA HV AL + + + +N+GTGKG SV ELV FE+V+ +
Sbjct: 240 YIHVLDLADAHVKALRFAANVADKKGLCEAFNIGTGKGHSVMELVKTFEQVSGLSLNYLL 299
Query: 172 VDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
+RR GDI ++A A+++LGW Q IEE D W WQ
Sbjct: 300 GERRSGDIEQIYASVDKAQQQLGWVAQRDIEEGLRDAWNWQ 340
>UniRef50_Q1MP11 Cluster: Nucleoside-diphosphate-sugar epimerases;
n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
Nucleoside-diphosphate-sugar epimerases - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 339
Score = 212 bits (518), Expect = 6e-54
Identities = 103/212 (48%), Positives = 136/212 (64%), Gaps = 2/212 (0%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSSS TVYG P++LP+TE HP +I N YG+TK IE+++ D++ A +N LRYFN
Sbjct: 120 IFSSSATVYGIPQYLPLTEEHPLAAI-NPYGKTKLHIEQIIFDVANAYPMFNAFILRYFN 178
Query: 62 PVGAHPSGLI-GEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
PVG G I GE TN+MP + QVA G + + +FG DY T DGTG+RDYIHV D
Sbjct: 179 PVGGGGKGFILGEHSKNAPTNVMPIICQVAAGIQKEIYIFGDDYETIDGTGVRDYIHVTD 238
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
L +GH+AAL + +YNLGTGKG+SV EL++ FE+V VP V RR GD++
Sbjct: 239 LIAGHMAALKKAEENKTGCHIYNLGTGKGISVLELIHTFEKVNNISVPYCVVARRSGDVA 298
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
+ +AD + A EL W Q +E+M D W WQ
Sbjct: 299 SCYADPTKAFRELNWKAQKGLEDMVYDSWLWQ 330
>UniRef50_A4QBQ0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 335
Score = 203 bits (495), Expect = 3e-51
Identities = 100/211 (47%), Positives = 132/211 (62%), Gaps = 3/211 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSSC+V+GE H P+ E PT N Y TK E+ML L AD+ W+ ISLRYF
Sbjct: 124 IVFSSSCSVHGETTHSPLNEDSPTQP-ANPYAFTKLTGEKMLSQLVEADESWSAISLRYF 182
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP+GAHPSG +GE N+MP+L VA G+K L VFG D+ TPDGT IRDY+HV+D
Sbjct: 183 NPIGAHPSGKLGESGLGRPRNIMPWLLDVAAGRKQSLEVFGDDWPTPDGTCIRDYLHVVD 242
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A HV AL + +V+N+GTG G SV EL+N E T ++P + RR GD+S
Sbjct: 243 VARVHVRALEHFKTG--QAEVFNIGTGVGTSVLELINTMEEATGREIPYEISARRSGDVS 300
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A+ AD + GW + ++ +MC D WR+
Sbjct: 301 ALVADAQRVATQWGWVPEFSVFQMCADAWRF 331
>UniRef50_A3PE72 Cluster: UDP-glucose 4-epimerase; n=2;
Prochlorococcus marinus|Rep: UDP-glucose 4-epimerase -
Prochlorococcus marinus (strain MIT 9301)
Length = 352
Score = 202 bits (494), Expect = 5e-51
Identities = 100/221 (45%), Positives = 136/221 (61%), Gaps = 3/221 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAAD-DKWNIISLRY 59
++FSS+ +YG+ E ET I N YG TK IE++L DL ++ + W I +LRY
Sbjct: 133 IIFSSTAALYGKSESKVFKETSIKSPI-NPYGETKLAIEKLLNDLYKSNPNSWKIANLRY 191
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FNP+G H SG IGE P + TN+ P + + A + +++FG D+ T DGTGIRDYIHVM
Sbjct: 192 FNPIGCHNSGQIGESPLNKPTNIFPLIIKAASKEIKKISIFGNDWPTHDGTGIRDYIHVM 251
Query: 120 DLASGHVAALN-LLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
DLA GH+ A+ L+S+ L NLG G GVSV EL+N F +V + ++ +RR GD
Sbjct: 252 DLAEGHIKAIEFLMSKNKGNLINLNLGRGVGVSVLELINTFTKVNNVNIEYEFAERREGD 311
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
+ AD LAK L W + IEEMC D W+W+ +NP GY
Sbjct: 312 VPISIADNCLAKTLLNWCPKRDIEEMCIDGWKWKLLNPKGY 352
>UniRef50_A0VUL2 Cluster: UDP-glucose 4-epimerase; n=2;
Rhodobacterales|Rep: UDP-glucose 4-epimerase -
Dinoroseobacter shibae DFL 12
Length = 359
Score = 201 bits (491), Expect = 1e-50
Identities = 103/211 (48%), Positives = 131/211 (62%), Gaps = 2/211 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG P+ P ET P + N YG TK E +L L+ +D KW +LRYF
Sbjct: 121 LVFSSSATVYGIPDVTPTPETAPHRHM-NPYGLTKITGELILDALATSDPKWAFGTLRYF 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP GAH S LIGEDP+ NLMP++AQVA+G++P L VFG DY TPDGTG+RDYIHV D
Sbjct: 180 NPAGAHGSALIGEDPSDIPNNLMPYIAQVAMGQRPHLQVFGDDYPTPDGTGVRDYIHVED 239
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA GHV +L L +T + NLGTG+G SV E+V + +P + VDRR GD+
Sbjct: 240 LAEGHVLSLKSLLETG-ESHLVNLGTGRGYSVLEMVAAYSAACGRALPYRIVDRRPGDVP 298
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A A+ LG+ + + +MC W W
Sbjct: 299 IYCATVERARALLGFEAKRDLAQMCASSWAW 329
>UniRef50_Q0U254 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 477
Score = 196 bits (478), Expect = 4e-49
Identities = 103/245 (42%), Positives = 153/245 (62%), Gaps = 25/245 (10%)
Query: 1 MVFSSSCTVYGEPEH--LPITET----HPT------GS----------ITNVYGRTKYFI 38
+VFSSS TVYGE + +P+ E HP GS +T+ YGR+K+
Sbjct: 227 LVFSSSATVYGEGANCGVPLREELCVHHPESFVDSDGSERQVIPGVMGLTSPYGRSKFMC 286
Query: 39 EEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLT 98
E +L D++ +D W+I +LRYFNPVG H SG++GEDP ++ +NL+P +A V G +PVL
Sbjct: 287 ESILADVARSDPSWSITALRYFNPVGCHESGILGEDPRQKPSNLIPVIATVLTGTRPVLD 346
Query: 99 VFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIR--LKVYNLGTGKGVSVKELV 156
+FGTD+NTPDGT +RD+IHV+DLA GH+AAL + I+ + YNLGTG+G +V+E++
Sbjct: 347 IFGTDWNTPDGTAVRDFIHVVDLARGHIAALAASAAGRIKTAFRTYNLGTGRGHTVREVL 406
Query: 157 NVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW-QTMN 215
+ E+ ++ +P + V RR GD+ A+ A+EEL W T+++ D W + +
Sbjct: 407 SSLEQASRRTIPAREVGRRAGDVGFCVAEVRRAEEELQWRATRTLDDCSGDVWNFTKARC 466
Query: 216 PDGYP 220
DG P
Sbjct: 467 ADGTP 471
>UniRef50_A2R0Z8 Cluster: Catalytic activity: UDPglucose =
UDPgalactose; n=1; Aspergillus niger|Rep: Catalytic
activity: UDPglucose = UDPgalactose - Aspergillus niger
Length = 407
Score = 196 bits (478), Expect = 4e-49
Identities = 92/195 (47%), Positives = 123/195 (63%), Gaps = 2/195 (1%)
Query: 17 PITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPT 76
PIT ITN YGRTK+ E +L D++A+D W II LRYFNP+G PSGL+GEDP
Sbjct: 200 PITSEQGCTGITNPYGRTKWIGEAILSDVAASDPSWTIIGLRYFNPIGCDPSGLLGEDPR 259
Query: 77 KEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAAL--NLLSQ 134
+NL+P + QV G+ P L+V+GTD+ TPDGT IRD+IHV D+A GH AAL L Q
Sbjct: 260 GTPSNLVPVVVQVLTGQLPALSVYGTDWETPDGTAIRDFIHVSDVARGHTAALAAALAGQ 319
Query: 135 THIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELG 194
+ +NLGTG+G SV E+V+ E V+ +P + +RR GD+ A A ELG
Sbjct: 320 VKTNFRTFNLGTGRGHSVAEVVSAMEGVSHQSIPRRLAERRPGDVQECVAVPERAACELG 379
Query: 195 WSTQLTIEEMCTDFW 209
W + ++++ C D W
Sbjct: 380 WEAEKSLQDACEDLW 394
>UniRef50_Q5KUQ5 Cluster: UDP-glucose 4-epimerase; n=5;
Bacteria|Rep: UDP-glucose 4-epimerase - Geobacillus
kaustophilus
Length = 323
Score = 195 bits (475), Expect = 9e-49
Identities = 100/214 (46%), Positives = 133/214 (62%), Gaps = 3/214 (1%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ YG P ITE PT I N YGR+K IE++L D ++A N + LRYFN
Sbjct: 111 IFSSTAATYGIPNVELITEDCPTNPI-NPYGRSKLMIEQILADFASAYGL-NYVVLRYFN 168
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GAH SG IGED E T+L+P + Q LG++ ++VFGTDY+TPDGT IRDYIHV DL
Sbjct: 169 AAGAHESGEIGEDHNPE-THLIPLVLQHLLGQRDKISVFGTDYDTPDGTCIRDYIHVTDL 227
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A H+ AL L + VYNLG G G SVKE++ E+VT K ++Y DRR GD +
Sbjct: 228 AKAHILALEALLSGKKKTAVYNLGNGLGYSVKEVIETCEKVTGRKAVIEYTDRRPGDPAR 287
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
+ A + EELGW + ++E++ W+W + N
Sbjct: 288 LVASSQKIYEELGWKAEYSLEQIIESAWKWHSRN 321
>UniRef50_Q5K809 Cluster: Galactose metabolism-related protein,
putative; n=7; Basidiomycota|Rep: Galactose
metabolism-related protein, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 390
Score = 194 bits (474), Expect = 1e-48
Identities = 106/243 (43%), Positives = 152/243 (62%), Gaps = 25/243 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDL-----SAADDKW-NI 54
+VFSSS TVYG P +PI ET +VYGRTK EE+++D+ + AD++
Sbjct: 147 LVFSSSATVYGTPAVIPIPETSEIIP-ESVYGRTKAITEEVIRDVCRAGAATADNQGLKA 205
Query: 55 ISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGK-KPVLTVFGTDYNTPDGTGIR 113
IS+RYFNP GAHPSG +GE+P NL+P LAQ+A+G+ L VFG DY T DGT +R
Sbjct: 206 ISVRYFNPAGAHPSGKLGEEPKGRPGNLLPILAQIAVGRLSSDLKVFGNDYPTRDGTCLR 265
Query: 114 DYIHVMDLASGHVAALNLLSQTHIR-----------------LKVYNLGTGKGVSVKELV 156
DY+H+MDLA GH+ AL+ L+++ I+ + +NLG GKG++V E++
Sbjct: 266 DYLHIMDLAEGHLLALDALAKSEIKTQSSGIFQSIDTKKEGYFRAFNLGRGKGITVLEMI 325
Query: 157 NVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNP 216
N + T + + V+RR GD+ + AD LA+EELG+ + ++EMC D WR+Q+ N
Sbjct: 326 NEMKIATGYEYQFEIVERRSGDVPDLTADPRLAQEELGFIARRGLQEMCQDLWRFQSSNV 385
Query: 217 DGY 219
+GY
Sbjct: 386 NGY 388
>UniRef50_Q5QPP4 Cluster: UDP-galactose-4-epimerase; n=6; cellular
organisms|Rep: UDP-galactose-4-epimerase - Homo sapiens
(Human)
Length = 239
Score = 194 bits (473), Expect = 2e-48
Identities = 98/204 (48%), Positives = 134/204 (65%), Gaps = 27/204 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG P++LP+ E HPTG TN YG++K+FIEEM++DL AD WN + LRYF
Sbjct: 63 LVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNAVLLRYF 122
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP GAH SG IGEDP NLMP+++QVA+G++ L VFG DY+T DGTG+RDYIHV+D
Sbjct: 123 NPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRDYIHVVD 182
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
L++ HI ++++L + ++P K V RR GD++
Sbjct: 183 -----------LAKGHI------------AALRKL----KEQCGCRIPYKVVARREGDVA 215
Query: 181 AMWADTSLAKEELGWSTQLTIEEM 204
A +A+ SLA+EELGW+ L ++ M
Sbjct: 216 ACYANPSLAQEELGWTAALGLDRM 239
>UniRef50_Q5QXD9 Cluster: UDP-glucose 4-epimerase; n=1; Idiomarina
loihiensis|Rep: UDP-glucose 4-epimerase - Idiomarina
loihiensis
Length = 335
Score = 190 bits (462), Expect = 3e-47
Identities = 90/215 (41%), Positives = 131/215 (60%), Gaps = 1/215 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSS VYG P +P+ E+ P G+ TN YG KY E L + + ++ ISLRYF
Sbjct: 121 LIFSSSAVVYGNPSCVPVAESAPAGATTNPYGENKYRSECDLAEFCEKNLAFSAISLRYF 180
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP GAHPSG+IGE P K NL+P + V K + V+G DY+T DGT IRDYIHV D
Sbjct: 181 NPAGAHPSGVIGEQPIKPAANLIPAIGNVITRKVDSVQVYGGDYSTCDGTAIRDYIHVCD 240
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A GHVAAL ++NLGTGKG SV +++ FE+ + +P+ + +RR GD++
Sbjct: 241 VAKGHVAALE-AGFARTGHHIFNLGTGKGESVLGVIHAFEQASGQIIPVNFSERRQGDVA 299
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
+ +A A +EL W + ++ + D+ W +++
Sbjct: 300 SCYAQADKALQELNWRAEHDLQTIARDYCHWLSLS 334
>UniRef50_A5AK58 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 477
Score = 187 bits (456), Expect = 2e-46
Identities = 106/223 (47%), Positives = 133/223 (59%), Gaps = 29/223 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRT-------------------KYFIEEM 41
MVFSSS TVYG+P+ +P E ++ N YGRT KY +
Sbjct: 66 MVFSSSATVYGQPDKIPCVEDFNLMAM-NPYGRTKSGQTPLRQCQCSLIPCLPKYSLIPW 124
Query: 42 LK--------DLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGK 93
LK D+ A+ W II LRYFNPVGAH SG +GEDP NLMP++ QVA+G+
Sbjct: 125 LKLFLEEIARDIQKAEPDWKIILLRYFNPVGAHESGKLGEDPKGIPNNLMPYIQQVAVGR 184
Query: 94 KPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAAL-NLLSQTHIRLKVYNLGTGKGVSV 152
P L V+G DY T DG+ IRDYIHVMDLA GH+AAL L + I YNLGTG+G SV
Sbjct: 185 LPELNVYGHDYPTRDGSAIRDYIHVMDLADGHIAALRKLFTSEDIGCTAYNLGTGQGTSV 244
Query: 153 KELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGW 195
E+V FE+ + K+P+K RR GD +A++A T A +ELGW
Sbjct: 245 LEMVAAFEKASGKKIPIKLCPRRAGDATAVYASTEKAAKELGW 287
>UniRef50_Q2UPV8 Cluster: UDP-glucose 4-epimerase; n=7;
Trichocomaceae|Rep: UDP-glucose 4-epimerase -
Aspergillus oryzae
Length = 428
Score = 187 bits (456), Expect = 2e-46
Identities = 86/181 (47%), Positives = 124/181 (68%), Gaps = 2/181 (1%)
Query: 27 ITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFL 86
ITN YGRTK+ E +L DL+A+D +W I++LRYFNPVG SGL+GEDP + TNL+P +
Sbjct: 234 ITNPYGRTKWICEAILADLAASDPEWTIVALRYFNPVGCDESGLLGEDPKQIPTNLLPVV 293
Query: 87 AQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIR--LKVYNL 144
+V G+ L +FGTD++T DGT +RD+IHV DLA GH+AAL+ ++ ++ + +NL
Sbjct: 294 VKVMTGQYKELQMFGTDWDTEDGTAVRDFIHVTDLARGHIAALSAANEGKLKENFRTFNL 353
Query: 145 GTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEM 204
GTG G SV E+VN E V+ +P + DRR GD+ + A + ++EEL W T+ T+ +
Sbjct: 354 GTGTGHSVMEVVNTMESVSSKAIPRRAADRRAGDVGSCVAVATRSQEELQWKTEKTLTDA 413
Query: 205 C 205
C
Sbjct: 414 C 414
>UniRef50_Q8R8R8 Cluster: UDP-glucose 4-epimerase; n=15;
Bacteria|Rep: UDP-glucose 4-epimerase -
Thermoanaerobacter tengcongensis
Length = 329
Score = 186 bits (452), Expect = 6e-46
Identities = 99/222 (44%), Positives = 139/222 (62%), Gaps = 5/222 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ VYGEPE +PI E T TN YG TK IE+MLK AA ++LRYF
Sbjct: 111 IVFSSTAAVYGEPERIPIEEEDRTEP-TNPYGETKLAIEKMLKWADAAYGI-KYVALRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA +G IGED + E T+L+P + QVALGK+ + ++G DY T DGT IRDYIHVMD
Sbjct: 169 NVAGALETGEIGEDHSPE-THLIPIILQVALGKRDKVMIYGDDYPTKDGTPIRDYIHVMD 227
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
L H+ AL L + + + +VYNLG G+G +VKE++ V +VT +P + RR GD +
Sbjct: 228 LVDAHILALEKLRKEN-KSEVYNLGNGEGFTVKEVIEVARKVTGHPIPAEVTGRRPGDPA 286
Query: 181 AMWADTSLAKEELGWSTQ-LTIEEMCTDFWRWQTMNPDGYPK 221
+ A + A ++LGW + ++EE+ W W +P+G+ +
Sbjct: 287 VLVASSEKAMKDLGWRPKYASLEEIIKSAWMWHKNHPNGFKR 328
>UniRef50_Q4WQU9 Cluster: UDP-glucose 4-epimerase; n=3;
Pezizomycotina|Rep: UDP-glucose 4-epimerase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 415
Score = 185 bits (450), Expect = 1e-45
Identities = 88/192 (45%), Positives = 119/192 (61%), Gaps = 3/192 (1%)
Query: 20 ETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEF 79
E H ITN YGRTK F E +L DL+ A+ W I++LRYFNP+G SGL+GEDP
Sbjct: 220 EIH-NSQITNPYGRTKLFGEAILADLARANPAWTIVALRYFNPIGCDASGLLGEDPKVHP 278
Query: 80 TNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIR- 138
+NL+P L ++ G++ L ++G+D+ TPDGT +RD+IHV D+A GH AAL +R
Sbjct: 279 SNLVPALVEILTGRRTELLIYGSDWETPDGTPVRDFIHVTDVARGHTAALAAARDGRVRD 338
Query: 139 -LKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWST 197
+ +NLGTG+G SV ELV E V+ +P + V RR GDI + A A ELGW+T
Sbjct: 339 GFRTFNLGTGRGHSVLELVQTLETVSGRTIPRRVVGRRAGDIGSCVASAERAAAELGWTT 398
Query: 198 QLTIEEMCTDFW 209
++ C D W
Sbjct: 399 AKSLTNACEDLW 410
>UniRef50_Q9ABX8 Cluster: UDP-glucose 4-epimerase; n=1; Caulobacter
vibrioides|Rep: UDP-glucose 4-epimerase - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 327
Score = 182 bits (443), Expect = 7e-45
Identities = 92/211 (43%), Positives = 129/211 (61%), Gaps = 4/211 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+C +G+P LP+ ETHP + N YGR+K +E+ L D + + +RYF
Sbjct: 112 VVFSSTCATFGDPVDLPMKETHPQAPL-NPYGRSKLMVEQALADYDRYVGLKSAV-MRYF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P G IGE E T+ +P QVALG++P T+FG DY+T DGT +RDY+HV+D
Sbjct: 170 NAAGADPQGRIGEWHEPE-THAVPLAIQVALGQRPRFTIFGDDYDTRDGTAVRDYVHVLD 228
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA HVAAL L + YNLGTG G +V+ELV+ +V A +P++ RR GD
Sbjct: 229 LADAHVAALKRL-LVGGSSETYNLGTGTGTTVRELVDGVGKVAGAPLPVEIASRRPGDAP 287
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ D + A+ ELGW +++E+ + WRW
Sbjct: 288 VLVGDHAKARAELGWKASRSLDEILSTAWRW 318
>UniRef50_UPI00006CC433 Cluster: UDP-glucose 4-epimerase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
UDP-glucose 4-epimerase family protein - Tetrahymena
thermophila SB210
Length = 369
Score = 180 bits (437), Expect = 4e-44
Identities = 88/219 (40%), Positives = 134/219 (61%), Gaps = 5/219 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ TVYGE ++ E + + + Y +TK E ++K + AA ++ LRYFN
Sbjct: 152 IFSSTATVYGETDNCD--EDNLLNPLQS-YAQTKTCCEFLMKAMCAAHPSVRMVCLRYFN 208
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
P GAH SGLIG+ P+ NL PFL QV +GK+ L +FG DYNT DGTG+RD+IHV+DL
Sbjct: 209 PAGAHSSGLIGDSPSVYPNNLFPFLEQVVIGKREKLYIFGNDYNTYDGTGVRDFIHVVDL 268
Query: 122 ASGHVAALNLLSQTH--IRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
A H++A++ LS+ + + N+GTG G+SV + V + +V ++P ++ RR GD+
Sbjct: 269 ACAHISAIDYLSKLNDTKNFEAINIGTGSGISVLDTVTTYSKVIGRQIPYEFTKRRDGDV 328
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDG 218
+ A A + L W T+E++C D + + NP+G
Sbjct: 329 GQLVAKAEKASKILNWKAVKTLEDICRDSYNFIQKNPNG 367
>UniRef50_A2BSF0 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. AS9601|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain AS9601)
Length = 355
Score = 179 bits (436), Expect = 5e-44
Identities = 88/219 (40%), Positives = 133/219 (60%), Gaps = 2/219 (0%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDK-WNIISLRY 59
++FSSS TVY ++ I+E + N YG TK E++++D+ +DDK W I +LRY
Sbjct: 132 LIFSSSATVYKIDKNEKISENGILSPL-NPYGNTKLSNEKIIEDVFKSDDKRWKIANLRY 190
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FNP GAH SG+IGE+P +N+ P + +V + L ++G+D+ T DGT IRDYIHVM
Sbjct: 191 FNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDGTCIRDYIHVM 250
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA H+AAL L + N+GTG G+SV EL+ F V ++P + ++R GD
Sbjct: 251 DLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPYYFTEKRKGDA 310
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDG 218
+ + A+ SL + L W + ++++C D WRW + +G
Sbjct: 311 AFVVANNSLVIQTLKWEPKRNLKDICKDSWRWFIKSKEG 349
>UniRef50_Q8DGV6 Cluster: UDP-glucose 4-epimerase; n=1;
Synechococcus elongatus|Rep: UDP-glucose 4-epimerase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 308
Score = 175 bits (427), Expect = 6e-43
Identities = 89/211 (42%), Positives = 131/211 (62%), Gaps = 5/211 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ VYG P +PI+ET P I N YGR+K+ +E+M+ D+ A ++I RYFN
Sbjct: 89 IFSSTAAVYGVPPEIPISETCPCAPI-NPYGRSKWMVEQMVADMGTAYGLKSVI-FRYFN 146
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA P +GED E T+L+P + Q A+G++P + ++GTDY TPDGT IRDYIHV+DL
Sbjct: 147 AAGADPHSRLGEDHRPE-THLIPLVLQAAMGRRPHIAIYGTDYPTPDGTCIRDYIHVVDL 205
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A HV L L +++NLG +G SV++++ +RVT +P+ DRR GD +
Sbjct: 206 AQAHVRGLKYLLSGG-NSQIFNLGNAQGFSVRQIIETAQRVTGCSIPVIEGDRRAGDPAI 264
Query: 182 MWADTSLAKEELGWSTQL-TIEEMCTDFWRW 211
+ A++ A+ LGW Q IE++ W+W
Sbjct: 265 LVANSDRARCLLGWQPQYPDIEQIIHHAWQW 295
>UniRef50_Q8YN57 Cluster: UDP-glucose 4-epimerase; n=43;
Bacteria|Rep: UDP-glucose 4-epimerase - Anabaena sp.
(strain PCC 7120)
Length = 332
Score = 175 bits (425), Expect = 1e-42
Identities = 92/211 (43%), Positives = 129/211 (61%), Gaps = 5/211 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSS+C YG P+ +PI E HP I N YG TK +E +L D A ++ RYFN
Sbjct: 120 VFSSTCATYGVPKTVPIPEDHPQNPI-NPYGATKLMVERILADFDVAYGLKSV-RFRYFN 177
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA+P GL+GED E T+L+P + ALGK+ +++FGTDY TPDGT IRDYIHV DL
Sbjct: 178 AAGANPDGLLGEDHNPE-THLIPLVLLTALGKRKFISIFGTDYPTPDGTCIRDYIHVNDL 236
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A HV L L + +V+NLG G+G SV+E++ E+VT + ++ DRR GD +
Sbjct: 237 ADAHVLGLKYLLKGG-DSEVFNLGNGQGFSVREVIAAGEQVTGLPITVEECDRRPGDPPS 295
Query: 182 MWADTSLAKEELGWSTQL-TIEEMCTDFWRW 211
+ A++ LGW Q +I+++ + W+W
Sbjct: 296 LIGSGEKARKILGWQPQYSSIKDIVSHAWQW 326
>UniRef50_Q9SGX0 Cluster: F1N19.2; n=1; Arabidopsis thaliana|Rep:
F1N19.2 - Arabidopsis thaliana (Mouse-ear cress)
Length = 447
Score = 174 bits (424), Expect = 1e-42
Identities = 106/262 (40%), Positives = 138/262 (52%), Gaps = 37/262 (14%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS TVYG P+ +P TE P ++ YGRTK FIE++ +D+ D +W II LRYF
Sbjct: 187 LVFSSSATVYGWPKEVPCTEESPLSGMSP-YGRTKLFIEDICRDVQRGDPEWRIIMLRYF 245
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIR---DYIH 117
NPVGAHPSG IGEDP NLMP++ QV +G+ P L ++GTDY T DGTG+R Y
Sbjct: 246 NPVGAHPSGRIGEDPCGTPNNLMPYVQQVVVGRLPNLKIYGTDYTTKDGTGVRLSHPYTT 305
Query: 118 VMDL--------ASGHVAALNLLSQTHIR--LKVYNLGTGKGVSVKEL------------ 155
+ +L L+L H+R + V +L G ++++L
Sbjct: 306 IRNLNCPLNPCITLTQTCFLSLFHMNHVRDYIHVVDLADGHICALQKLDDTEIGCEVYNL 365
Query: 156 -----VNVFERV---TKA---KVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEM 204
V E V KA K+PL V RR GD ++A T A+ EL W IEEM
Sbjct: 366 GTGKGTTVLEMVDAFEKASGMKIPLVKVGRRPGDAETVYASTEKAERELNWKANFGIEEM 425
Query: 205 CTDFWRWQTMNPDGYPKKTKKT 226
C D W W + NP GY T
Sbjct: 426 CRDQWNWASNNPFGYGSSPNST 447
>UniRef50_A6C8E4 Cluster: UDP-glucose 4-epimerase; n=1; Planctomyces
maris DSM 8797|Rep: UDP-glucose 4-epimerase -
Planctomyces maris DSM 8797
Length = 345
Score = 174 bits (423), Expect = 2e-42
Identities = 93/220 (42%), Positives = 128/220 (58%), Gaps = 5/220 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+C YG PE +P+TE I N YG +K FIE++L D +++ + I LRYF
Sbjct: 112 IVFSSTCATYGIPEQIPVTEESAQTPI-NPYGWSKLFIEQILTDCASSYPNFGFIGLRYF 170
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +G +GED + E T+L+P LGK+ +T+ G DY T DGT IRDYIHV D
Sbjct: 171 NVAGCAMNGSLGEDHSPE-THLIPNCLNTVLGKQSHVTILGNDYPTADGTCIRDYIHVED 229
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ H+ ALN L+ R YN+G G G SV ++V E+VT ++P++Y RR GD
Sbjct: 230 ICRAHLLALNALTPQANRF--YNVGLGSGFSVLDVVKTTEQVTGREIPVEYQARRPGDPP 287
Query: 181 AMWADTSLAKEELGWSTQLT-IEEMCTDFWRWQTMNPDGY 219
+ A ELGWS + T + E+ W W +PDGY
Sbjct: 288 MLSASHEKITRELGWSPRHTSLTEIIESAWNWFQKHPDGY 327
>UniRef50_Q9KDV3 Cluster: UDP-glucose 4-epimerase; n=124; cellular
organisms|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 334
Score = 173 bits (422), Expect = 2e-42
Identities = 96/225 (42%), Positives = 132/225 (58%), Gaps = 5/225 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ YGEP +PI E+ PT TN YG TK IE+M A + LRYF
Sbjct: 111 IVFSSTAATYGEPVQIPIQESDPTIP-TNPYGETKLAIEKMFHWCQEAYGL-QYVCLRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P+G IGED + E ++L+P + QVALG++ + +FG DY T DG+ IRDYIHVMD
Sbjct: 169 NAAGADPNGRIGEDHSPE-SHLIPIVLQVALGQRERVAIFGDDYQTEDGSCIRDYIHVMD 227
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA+ H A L + + +NLG GKG SVKE++ V +VT +P + RR GD +
Sbjct: 228 LANAHYLACEHLRKDG-QSGSFNLGNGKGFSVKEVIEVCRQVTGHPIPAEIAPRRSGDPA 286
Query: 181 AMWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPDGYPKKTK 224
++ A + A+ LGW + ++E M W W +P GY + K
Sbjct: 287 SLIASSEKAQTILGWEPKYPSLETMVEHAWNWHKEHPHGYSTENK 331
>UniRef50_Q1GKR7 Cluster: UDP-glucose 4-epimerase; n=17;
Bacteria|Rep: UDP-glucose 4-epimerase - Silicibacter sp.
(strain TM1040)
Length = 327
Score = 171 bits (415), Expect = 2e-41
Identities = 91/211 (43%), Positives = 127/211 (60%), Gaps = 5/211 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSS+C YGE +++ + E P + N YG +K +E++LKD AA ++I RYFN
Sbjct: 113 VFSSTCATYGEHDNVVLDENTPQQPL-NAYGASKRAVEDILKDFEAAHGLRSVI-FRYFN 170
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA P +GE E T+L+P + Q G++ LTVFGTDY+TPDGT IRDY+HV DL
Sbjct: 171 VAGADPEAEVGEFHQPE-THLVPLMIQAIKGERAALTVFGTDYDTPDGTCIRDYVHVCDL 229
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
H+ L L +V+NLGTG G SVKE+++ VT +VP RR GD +
Sbjct: 230 VDAHILGLKWLEDGK-GSRVFNLGTGTGFSVKEVLSHSHAVTNTEVPHVIGPRRAGDCTK 288
Query: 182 MWADTSLAKEELGWS-TQLTIEEMCTDFWRW 211
+ + + A EELGW + T+++M +D WRW
Sbjct: 289 LVSGSVRAGEELGWEPKRSTMDQMISDAWRW 319
>UniRef50_P96995 Cluster: UDP-glucose 4-epimerase; n=51;
Bacteria|Rep: UDP-glucose 4-epimerase - Streptococcus
mutans
Length = 333
Score = 171 bits (415), Expect = 2e-41
Identities = 91/220 (41%), Positives = 125/220 (56%), Gaps = 5/220 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ YG P+ +PI ET P I N YG +K +E ++K A + LRYF
Sbjct: 114 IVFSSTAATYGIPDEIPIKETTPQRPI-NPYGESKLMMETIMKWSDRAYGI-KFVPLRYF 171
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P G IGED + E T+L+P + QVA G + + +FG DYNTPDGT +RDY+H D
Sbjct: 172 NVAGAKPDGSIGEDHSPE-THLLPIILQVAQGVREKIMIFGDDYNTPDGTNVRDYVHPFD 230
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA H+ ALN L Q + +NLG+ G S +++ +VT K+P + RR GD
Sbjct: 231 LADAHLLALNYLRQGN-PSTAFNLGSSTGFSNLQILEAARKVTGQKIPAEKAARRSGDPD 289
Query: 181 AMWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPDGY 219
+ A + A+E LGW Q IE++ W W + P GY
Sbjct: 290 TLIASSEKAREVLGWKPQFDDIEKIIASAWAWHSSYPKGY 329
>UniRef50_Q1YMT2 Cluster: UDP-glucose 4-epimerase; n=3;
Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
Aurantimonas sp. SI85-9A1
Length = 341
Score = 170 bits (414), Expect = 2e-41
Identities = 92/213 (43%), Positives = 121/213 (56%), Gaps = 4/213 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+C YG P+ P+TE H I+ YG +K +E +L+DLS D + LRYF
Sbjct: 119 IVFSSTCATYGIPQFTPLTEDHVQAPISP-YGWSKLLVEHILRDLSGLD-RIRCAILRYF 176
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P IGE T E T+ +P + + ALG++ T+FG DY+T DGT IRDY+HV+D
Sbjct: 177 NAAGADPEARIGEWHTPE-THAVPLVIETALGQRDCFTIFGDDYDTADGTCIRDYVHVID 235
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA HV A+ L + + NLGTG G SV ELV V+ V + DRR GD S
Sbjct: 236 LADAHVRAVEYLLNDGASVAL-NLGTGTGTSVAELVETVALVSGRPVKTRRADRRPGDPS 294
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQT 213
+ AD A++ LGW Q + WRW T
Sbjct: 295 ILLADNRRARDVLGWQPQHDLASSIESAWRWHT 327
>UniRef50_Q9SA77 Cluster: UDP-arabinose 4-epimerase 1; n=31;
Viridiplantae|Rep: UDP-arabinose 4-epimerase 1 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 419
Score = 169 bits (410), Expect = 7e-41
Identities = 88/232 (37%), Positives = 131/232 (56%), Gaps = 8/232 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+++SS+C YGEP+ +PITE P I N YG+ K E+++ D S D ++ LRYF
Sbjct: 191 LIYSSTCATYGEPDIMPITEETPQVPI-NPYGKAKKMAEDIILDFSKNSDM-AVMILRYF 248
Query: 61 NPVGAHPSGLIGEDPT---KEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
N +G+ P G +GE P +E + A G P L + GTDY T DGT +RDYI
Sbjct: 249 NVIGSDPEGRLGEAPRPELREHGRISGACFDAARGIMPGLQIKGTDYKTADGTCVRDYID 308
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V DL HV AL ++ +YN+GTGKG SVKE V ++ T ++ + Y+ RR G
Sbjct: 309 VTDLVDAHVKALQKAKPR--KVGIYNVGTGKGSSVKEFVEACKKATGVEIKIDYLPRRAG 366
Query: 178 DISAMWADTSLAKEELGWSTQLT-IEEMCTDFWRWQTMNPDGYPKKTKKTEI 228
D + +++D S ++EL W+ + T ++E WRWQ ++ +GY T +
Sbjct: 367 DYAEVYSDPSKIRKELNWTAKHTNLKESLETAWRWQKLHRNGYGLTTSSVSV 418
>UniRef50_Q59083 Cluster: UDP-glucose 4-epimerase; n=14;
Bacteria|Rep: UDP-glucose 4-epimerase - Azospirillum
brasilense
Length = 348
Score = 166 bits (403), Expect = 5e-40
Identities = 92/195 (47%), Positives = 119/195 (61%), Gaps = 4/195 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ VYG PE +PI E PT I N YG +K E+ML+D AA ++I LRYF
Sbjct: 120 VVFSSTAAVYGAPESVPIREDAPTVPI-NPYGASKLMTEQMLRDAGAAHGLRSVI-LRYF 177
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P+G G+ T T+L+ Q LG++P L +FGTDY+TPDGT IRDYIHV D
Sbjct: 178 NVAGADPAGRTGQ-ATPVATHLIKVACQALLGRRPPLAIFGTDYDTPDGTCIRDYIHVSD 236
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA HV AL L + L + N G G+G SV+E+V E V+ +VP + DRR GD
Sbjct: 237 LADAHVLALLHLRRGGGSL-LMNCGYGRGASVREVVRTLEEVSGEQVPATFADRRPGDPP 295
Query: 181 AMWADTSLAKEELGW 195
+ A +E+LGW
Sbjct: 296 QLVAGADRIREQLGW 310
>UniRef50_A3PE63 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9301|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain MIT 9301)
Length = 330
Score = 165 bits (402), Expect = 6e-40
Identities = 92/214 (42%), Positives = 134/214 (62%), Gaps = 9/214 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD-KWNIISLRY 59
+VFSSSC+VYGE +++PI E+ P ++ YG TK F E++LK S A +W +SLRY
Sbjct: 113 IVFSSSCSVYGEAKNVPINESEPLNPLSP-YGETKLFCEKILKWCSNAYGLRW--VSLRY 169
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKK-PVLTVFGTDYNTPDGTGIRDYIHV 118
FN GA IGE E T+++P LA ALG L +FG DY+T DGT +RD+IHV
Sbjct: 170 FNAAGADEDLEIGEKHDPE-THIIP-LAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHV 227
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
MDLAS H+ A+ L++ + ++NLG+G G S+K ++N E ++ +V LKY +RR D
Sbjct: 228 MDLASAHLKAIEYLAEGGMS-NIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREED 286
Query: 179 ISAMWADTSLAKEELGWSTQLT-IEEMCTDFWRW 211
S ++AD S AK L W + + ++ + W+W
Sbjct: 287 PSCLFADISKAKSILNWQPEFSNLDNILRSAWKW 320
>UniRef50_A6LLZ0 Cluster: UDP-glucose 4-epimerase; n=2;
Bacteria|Rep: UDP-glucose 4-epimerase - Thermosipho
melanesiensis BI429
Length = 321
Score = 165 bits (401), Expect = 8e-40
Identities = 85/210 (40%), Positives = 126/210 (60%), Gaps = 4/210 (1%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ VYG PE +PI E I N YG++K+ +E+ML+D A +I RYFN
Sbjct: 112 IFSSTAAVYGMPEKVPIKEDDKKDPI-NPYGKSKWMVEQMLEDYDKAYGLKSI-RFRYFN 169
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA G IGE E T+L+P + A+G++ + +FGT+Y+T DGT IRD++HV DL
Sbjct: 170 AAGADEEGEIGEAHKPE-THLIPLILDAAIGRRDSIKIFGTNYDTKDGTCIRDFVHVNDL 228
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A H+ L L + +NLG+G+G SV E++ +RVTK + DRR GD +
Sbjct: 229 ADAHIKGLEYLLDGG-KTDYFNLGSGEGYSVYEVIEAVKRVTKKNFKVVETDRRPGDPAY 287
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ AD++ AKE+LGW + +++E+ W W
Sbjct: 288 LIADSTKAKEKLGWEVKYSLDEIILTAWNW 317
>UniRef50_Q7CS52 Cluster: AGR_L_3011p; n=3; Alphaproteobacteria|Rep:
AGR_L_3011p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 356
Score = 161 bits (390), Expect = 2e-38
Identities = 91/196 (46%), Positives = 118/196 (60%), Gaps = 4/196 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSSC YG P+ LPI E + N YGRTK E L+D +AA ++LRYF
Sbjct: 142 LVFSSSCATYGVPQQLPIREETAQMPV-NPYGRTKLIFEMALEDYAAAYGL-RFVALRYF 199
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P G + E E T+L+P A + P L VFG DY+T DGT IRDYIHV D
Sbjct: 200 NAAGADPDGELYERHEPE-THLIPRALMAAAARLPQLDVFGADYDTSDGTCIRDYIHVSD 258
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA H+AA+N LS L+V NLG+G G SV +++ RVT +VP+ + RR GD
Sbjct: 259 LADAHLAAVNYLSDGGETLRV-NLGSGHGTSVGDIIRAIHRVTGQEVPVHFGARRAGDPP 317
Query: 181 AMWADTSLAKEELGWS 196
A++AD A+E LG++
Sbjct: 318 ALFADIRRAEETLGFT 333
>UniRef50_Q5FQW6 Cluster: UDP-glucose 4-epimerase; n=3;
Bacteria|Rep: UDP-glucose 4-epimerase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 328
Score = 158 bits (383), Expect = 1e-37
Identities = 93/223 (41%), Positives = 129/223 (57%), Gaps = 12/223 (5%)
Query: 1 MVFSSSCTVYGEPEHL-PITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIIS--L 57
+VFSS+ ++G PE L PI ET P + YG +K+ IE +L AD + + S L
Sbjct: 112 IVFSSTAALFGGPERLDPIPETAPVQP-GSPYGESKFMIERVLH---WADAIYGLRSACL 167
Query: 58 RYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
RYFN GA P G GED E T+L+P ALG++P L +FGTDY T DG+ +RDYIH
Sbjct: 168 RYFNAAGADPQGRAGEDHRPE-THLIPLTIDAALGRRPALKLFGTDYPTRDGSCVRDYIH 226
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V DLA HV A L Q R YN+G G+G S E++ ERV+ KVP + RR G
Sbjct: 227 VTDLADAHVRA---LGQIDHRSVTYNIGNGQGYSNLEVIQSVERVSGRKVPWEAAPRREG 283
Query: 178 DISAMWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPDGY 219
D + + AD++ + + GW+ + I+ + RW+ +P+GY
Sbjct: 284 DPALLVADSTTLRNDTGWTPRFGNIDSIVETALRWRESHPNGY 326
>UniRef50_Q011T8 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Ostreococcus tauri|Rep: Putative UDP-glucose 4-epimerase
- Ostreococcus tauri
Length = 430
Score = 155 bits (377), Expect = 7e-37
Identities = 83/217 (38%), Positives = 127/217 (58%), Gaps = 7/217 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
M++SS+C YG E LPITE+ PT I N YG++K + E ++KD + A+ K+ LRYF
Sbjct: 207 MIYSSTCATYGNVEKLPITESTPTKPI-NPYGKSKLYAENVIKDYALANPKFKTAILRYF 265
Query: 61 NPVGAHPSGLIGEDP---TKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
N G+ P G++GE P +E + A+GK LTV GT + T DGT IRD++H
Sbjct: 266 NVFGSDPDGVLGELPRAELREHGRISGACFDAAMGKVDKLTVMGTKHPTRDGTTIRDFVH 325
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDR-RL 176
V+DL H+A ++ +YN+GTG GVS++E V+ + VT ++ + Y + R
Sbjct: 326 VIDLVDAHIAVAE-KNKWDNPPSLYNVGTGSGVSMREFVDACKNVTGKQIEVYYREEPRP 384
Query: 177 GDISAMWADTSLAKEELGWSTQLT-IEEMCTDFWRWQ 212
GD + ++A+ K ELGWS + T + E W+++
Sbjct: 385 GDYAEVYANVDKIKHELGWSAKYTDLSESLAHAWKFR 421
>UniRef50_A0L5P6 Cluster: UDP-glucose 4-epimerase; n=4;
Bacteria|Rep: UDP-glucose 4-epimerase - Magnetococcus
sp. (strain MC-1)
Length = 337
Score = 154 bits (373), Expect = 2e-36
Identities = 88/218 (40%), Positives = 120/218 (55%), Gaps = 7/218 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSSC YGE +PITE I N YGR+K E ML+D ++LRYF
Sbjct: 112 IIFSSSCATYGEHRQMPITEAMSQHPI-NPYGRSKLMFEWMLQDYQVYG--LQSVALRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA G IGE E +++P L + A P T++GTDY + DGT +RDYIHV D
Sbjct: 169 NASGADLEGEIGEQHQPE-PHIIPRLLEAARKGSP-FTIYGTDYESEDGTCVRDYIHVSD 226
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA H+ AL L + + +NLG G+G S+++L+ V E VT + ++ RR GD +
Sbjct: 227 LAQAHLLALQWLWRGG-ESRAFNLGNGQGFSIRQLIKVAETVTGKSIAVQLGARRPGDPA 285
Query: 181 AMWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPD 217
+ A+EELGW Q T+E + T WRW D
Sbjct: 286 VLVGSAEKAREELGWQPQYGTLEIILTSAWRWMQRRQD 323
>UniRef50_A0LVI8 Cluster: UDP-glucose 4-epimerase; n=6;
Actinomycetales|Rep: UDP-glucose 4-epimerase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 329
Score = 151 bits (365), Expect = 2e-35
Identities = 91/220 (41%), Positives = 124/220 (56%), Gaps = 9/220 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSS+ VYGE I E P T+ YG +K ++ M+ D A +SLRYF
Sbjct: 109 LIFSSTAAVYGEGGPDGIGEDTPPRP-TSPYGTSKLAVDLMISDECRAYPL-GAVSLRYF 166
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA+ G GE E T+L+P VA G++P L ++G D+ TPDGT +RDYIHV+D
Sbjct: 167 NVAGAY--GPCGERHRTE-THLIPITLDVAAGRRPHLEIYGNDWPTPDGTCMRDYIHVLD 223
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA HV AL H +YNLG G+G SV+E+V ERVT +VP+ RR GD +
Sbjct: 224 LARAHVVALQHARPGH--HAIYNLGNGRGFSVREVVAAVERVTGRRVPVTVAPRRPGDPA 281
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW--QTMNPDG 218
+ AD S A+ EL W Q ++ + D W + Q + DG
Sbjct: 282 WLVADDSRARAELNWQPQADLDTIIADAWAFHQQRRHTDG 321
>UniRef50_Q604T5 Cluster: UDP-glucose 4-epimerase; n=26;
Proteobacteria|Rep: UDP-glucose 4-epimerase -
Methylococcus capsulatus
Length = 341
Score = 147 bits (356), Expect = 2e-34
Identities = 86/195 (44%), Positives = 111/195 (56%), Gaps = 4/195 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ VYG PE ET P I N YG +K E ML+DLS A +++ LRYFN
Sbjct: 115 IFSSTAAVYGIPEGEFALETSPLAPI-NPYGSSKLMSEIMLRDLSTASPLRHVV-LRYFN 172
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G+ P G IG+ K T L+ A+VA GK+ L +FGTDY TPDGTGIRDYIHV DL
Sbjct: 173 VAGSDPEGRIGQSTAKA-TLLIKVAAEVATGKRDRLCIFGTDYPTPDGTGIRDYIHVSDL 231
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A HVAAL L + + N G G G SV+E+++ RV + ++ RR GD
Sbjct: 232 ADAHVAALAYL-RAGGESRTLNCGYGHGYSVREIIDTMNRVNGTPIAVEERPRRPGDPPR 290
Query: 182 MWADTSLAKEELGWS 196
+ A +E L W+
Sbjct: 291 LVAGVERIREILEWT 305
>UniRef50_A6PV21 Cluster: UDP-glucose 4-epimerase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: UDP-glucose 4-epimerase -
Victivallis vadensis ATCC BAA-548
Length = 307
Score = 147 bits (355), Expect = 3e-34
Identities = 86/219 (39%), Positives = 122/219 (55%), Gaps = 11/219 (5%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSS+ +G+PE +PI E I N YG +K E++LK N +LRYFN
Sbjct: 97 VFSSTAATFGQPESIPIKEFDRQIPI-NPYGESKLCFEKILKWYHEIYGI-NYAALRYFN 154
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA + GED E T+L+P + Q GK+ L ++G DY+T DGT +RDYIH++DL
Sbjct: 155 AAGATEN--FGEDHRPE-THLIPLILQTVRGKRDKLMLYGDDYDTADGTCVRDYIHILDL 211
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A H AL+ H YNLGTG G+SV+E+++ E VT KV + RR GD +
Sbjct: 212 AQAHELALSAPESGH-----YNLGTGNGLSVREIIDAAEDVTGLKVNYEVAPRRPGDPAK 266
Query: 182 MWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPDGY 219
+ A + A+ L W + + ++ W+WQ +PDGY
Sbjct: 267 LIACSERARRMLKWEPKYESAHKIIESAWKWQLKHPDGY 305
>UniRef50_A2BZ28 Cluster: UDP-glucose 4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9515|Rep: UDP-glucose
4-epimerase - Prochlorococcus marinus (strain MIT 9515)
Length = 348
Score = 147 bits (355), Expect = 3e-34
Identities = 87/214 (40%), Positives = 119/214 (55%), Gaps = 7/214 (3%)
Query: 1 MVFSSSCTVYGEP--EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLR 58
+VFSSSC YG P +PI E P I N YGR+K +E++L D A + + LR
Sbjct: 128 IVFSSSCATYGIPLEAEIPIIERTPQNPI-NPYGRSKLMMEKILIDYHKAYEL-PVSILR 185
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
YFN GA +G IGED E T+L+P + + K+ L V G DY T DGT IRDY+HV
Sbjct: 186 YFNAAGADINGDIGEDHNPE-THLIPLVLEALSDKEGFLKVNGIDYPTFDGTCIRDYVHV 244
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
DLA HV ALN + L +YNLG GKG S+ E+++ ++VT ++ + RR GD
Sbjct: 245 SDLAKAHVLALNKIMNDK-SLSIYNLGNGKGYSIMEVIDASKKVTGKEIRILQSKRRQGD 303
Query: 179 ISAMWADTSLAKEELGWSTQL-TIEEMCTDFWRW 211
+ + AK+EL W + +E + W W
Sbjct: 304 PPVLISSPEKAKKELLWKPEFQDLESIIRTAWNW 337
>UniRef50_A0CJT6 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_2,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 314
Score = 146 bits (354), Expect = 4e-34
Identities = 85/187 (45%), Positives = 115/187 (61%), Gaps = 16/187 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSSS TVY E + E P +N YG TK IE +++ LS ++ + LRYFN
Sbjct: 128 LFSSSATVYAPGEF--VDEEAPFKP-SNPYGETKVVIEYLIRSLSKKGGRY--LCLRYFN 182
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
PVGA G +GE P K NL P++ QVA+G L VFG DYNT DGTGIRDYIH++DL
Sbjct: 183 PVGATKDGKLGEMPNKP-NNLFPYIEQVAIGNLQQLYVFGNDYNTHDGTGIRDYIHILDL 241
Query: 122 ASGHVAALNLLSQTHIRLKVY----NLGTGKGVSVKELVNVFERVTKAKVPLKY--VDRR 175
A HV AL L + + + Y N+GTGKG SV ++VN + ++ VP+KY D+R
Sbjct: 242 AEAHVVALQELIKKDEKKENYYDYFNIGTGKGFSVLDIVNEYSKL----VPIKYQITDKR 297
Query: 176 LGDISAM 182
+GD++ +
Sbjct: 298 VGDVAIL 304
>UniRef50_Q0C2X5 Cluster: UDP-glucose 4-epimerase; n=1; Hyphomonas
neptunium ATCC 15444|Rep: UDP-glucose 4-epimerase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 335
Score = 145 bits (351), Expect = 1e-33
Identities = 83/212 (39%), Positives = 117/212 (55%), Gaps = 5/212 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSS+C ++G + + E HP I N YG +K +E+ML A + LRYF
Sbjct: 113 IIFSSTCAIFGHAQTEFLAEDHPKNPI-NPYGMSKLMVEQMLAGFDHAHGIRSAC-LRYF 170
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA L GE E T+L+P + A T+ GTD++TPDGT +RDYIHV D
Sbjct: 171 NAAGADRQALTGERHACE-THLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVED 229
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA H+ ALN L Q +NLGTG+G SV E+V+ ER T ++P K RR GD +
Sbjct: 230 LAEAHLLALNALEQ-GAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAA 288
Query: 181 AMWADTSLAKEELGWSTQLT-IEEMCTDFWRW 211
+ A AK+ LGW+ + + ++ + T W
Sbjct: 289 RLIAAPGRAKDVLGWTAKRSDVDNIITSALAW 320
>UniRef50_A0Z893 Cluster: UDP-glucose 4-epimerase; n=1; marine gamma
proteobacterium HTCC2080|Rep: UDP-glucose 4-epimerase -
marine gamma proteobacterium HTCC2080
Length = 329
Score = 145 bits (351), Expect = 1e-33
Identities = 82/211 (38%), Positives = 114/211 (54%), Gaps = 4/211 (1%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSS+ VYG P+ I E HP + NVYG TK +E+ML + + LRYFN
Sbjct: 114 VFSSTAAVYGSPQARVIAEEHPLNPV-NVYGETKLAMEQMLSAVHK-QGAMQAVCLRYFN 171
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA P GE E T+L+P + + A G+ LT+FG DY+TPDGT IRDYIHV+DL
Sbjct: 172 AAGAAPDAHRGEWHEPE-THLIPNILRKAAGEDRALTIFGDDYDTPDGTCIRDYIHVLDL 230
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A H+ A+ +L + NLG+ G SV+E++ E + + RR GD +
Sbjct: 231 AQAHLKAMTMLHREG-GFHTLNLGSEAGYSVREILEACETTVGRPITHEIGPRRRGDPAR 289
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
+ AD S A + L W ++ E+ W W+
Sbjct: 290 LVADASRAGQILDWRATRSLGEIVESAWLWE 320
>UniRef50_UPI0000383ECD Cluster: COG1087: UDP-glucose 4-epimerase;
n=1; Magnetospirillum magnetotacticum MS-1|Rep: COG1087:
UDP-glucose 4-epimerase - Magnetospirillum
magnetotacticum MS-1
Length = 326
Score = 144 bits (348), Expect = 2e-33
Identities = 81/212 (38%), Positives = 114/212 (53%), Gaps = 8/212 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+C YG P +PI E+ P I N YG TK E L+ ++I LRYF
Sbjct: 114 IVFSSTCATYGTPSSVPIAESEPQIPI-NPYGETKLVFERALEWYERCHGIRHVI-LRYF 171
Query: 61 NPVGA-HPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N GA + G G + ++P A+G++P + +FGTDY T DGT +RDY+HV
Sbjct: 172 NAAGAAYGVGSYGNHDVR----MIPAAVLAAMGRRPPVKIFGTDYETSDGTCVRDYVHVA 227
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA GH AL L + + NLG+G+G SV ++ R+ VP + RRL D
Sbjct: 228 DLAEGHCLALEHLREDGASTAL-NLGSGRGSSVLNILEAVHRIGGRPVPNEKSPRRLCDP 286
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ ADT LA+ LGW T++++ + W W
Sbjct: 287 PTLIADTRLAQRILGWHPAYTLDDIISSVWHW 318
>UniRef50_Q1QJ29 Cluster: UDP-glucose 4-epimerase; n=1; Nitrobacter
hamburgensis X14|Rep: UDP-glucose 4-epimerase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 349
Score = 143 bits (347), Expect = 3e-33
Identities = 89/214 (41%), Positives = 120/214 (56%), Gaps = 10/214 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ VYG +E+ P + N YG++K IEE+L D A D N + RYF
Sbjct: 115 LVFSSTGAVYGNAG----SESAPRFPV-NPYGKSKLMIEEILSDYRQAYDL-NSVCFRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA G IGE E T+L+P G+ P +FG DY+TPDGT +RDYIHV D
Sbjct: 169 NASGADACGAIGECRDPE-THLIPRAMMALQGEIPDFGIFGDDYDTPDGTAVRDYIHVTD 227
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
L S HV A+N+L +R VYNLGTG G SV E+++ +K+P Y RR GD S
Sbjct: 228 LVSAHVQAVNML-MGGMR-GVYNLGTGVGYSVSEVLSAIFAEAGSKMPRVYYPRRPGDPS 285
Query: 181 AMWADTSLAKEELGWS-TQLTIEEMCTDFWRWQT 213
+ AD+S+A+ LG++ + + W W T
Sbjct: 286 VLIADSSVARMHLGFNPIHSNLGTIIRTAWNWHT 319
>UniRef50_Q9RSC3 Cluster: UDP-glucose 4-epimerase; n=1; Deinococcus
radiodurans|Rep: UDP-glucose 4-epimerase - Deinococcus
radiodurans
Length = 394
Score = 141 bits (341), Expect = 2e-32
Identities = 83/226 (36%), Positives = 117/226 (51%), Gaps = 6/226 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSS+ VYG + +PI E +VYG TK E+M+ A + LRYF
Sbjct: 112 LVFSSTAAVYGTTDAVPIPEDAAMQP-ESVYGETKRMSEQMIHAFHVAHGLPYTV-LRYF 169
Query: 61 NPVGAHPSGLIGE-DPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N GA P G IGE P K T+L+ ALG++ + +FG DY TPDGT IRDY+HV
Sbjct: 170 NVCGAAPGGDIGEAHPNK--THLIELACLTALGQREKMMIFGDDYPTPDGTCIRDYVHVQ 227
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA HV A+ L YN+G G G SV+E+++ + V + + RR GD
Sbjct: 228 DLADAHVLAVEALHAGKTDAATYNVGLGHGFSVREVLDAVDAVVGTPLQRELAPRRAGDP 287
Query: 180 SAMWADTSLAKEELGWSTQLT-IEEMCTDFWRWQTMNPDGYPKKTK 224
+ AD S ++LG++ + T + ++ W W +P G K
Sbjct: 288 PRLVADASRIVDQLGFAPKFTDLRDIVQTAWDWHRTHPQGLGSNNK 333
>UniRef50_Q8KGE4 Cluster: UDP-glucose 4-epimerase; n=14;
Bacteria|Rep: UDP-glucose 4-epimerase - Chlorobium
tepidum
Length = 329
Score = 140 bits (338), Expect = 4e-32
Identities = 80/210 (38%), Positives = 120/210 (57%), Gaps = 5/210 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSS ++G P +LPI E HP N YG TK IE +L+ ++RYF
Sbjct: 111 LLFSSSAAIFGSPAYLPIDENHPKKP-ENYYGFTKLEIERILEWYDRLKGL-KFAAVRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G G I + NL+P + +VA G +P+L+VFGTDY T DGT IRDY+HV D
Sbjct: 169 NAAGYDVRGRI-RGLERNPANLLPVIMEVASGVRPMLSVFGTDYPTRDGTCIRDYVHVND 227
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA+ HV A + ++ L V NLG+ GV+V E++ R+T ++ ++ RR GD +
Sbjct: 228 LATAHVLAFEQVIESGESLSV-NLGSETGVTVLEMLEAARRLTGKEIMAEFAPRRAGDPA 286
Query: 181 AMWADTSLAKEELGWSTQLT-IEEMCTDFW 209
+ A +++A+E LGW Q + ++ + W
Sbjct: 287 NLVATSAMARELLGWVPQYSDLDTLVESTW 316
>UniRef50_Q0BRM8 Cluster: UDP-glucose 4-epimerase; n=2;
Rhodospirillales|Rep: UDP-glucose 4-epimerase -
Granulobacter bethesdensis (strain ATCC BAA-1260 /
CGDNIH1)
Length = 342
Score = 140 bits (338), Expect = 4e-32
Identities = 85/221 (38%), Positives = 119/221 (53%), Gaps = 11/221 (4%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLRY 59
+ SS+ ++G + PI E + YG +K IE + LS AD + LRY
Sbjct: 127 LLSSTAALFGHHDDTPIDENAAIQP-GSPYGESKLMIE---RALSWADRIHGLRYACLRY 182
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN GA P G GED E T+L+P + ALG +P + VFG DY T DGT IRDYIHV
Sbjct: 183 FNAAGADPQGRSGEDHDPE-THLIPLVIDAALGLRPEIKVFGHDYPTRDGTCIRDYIHVS 241
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA H+AAL + Q VYNLG G G SV E+++ ERV+ VP++ RR GD
Sbjct: 242 DLAQAHLAALTRIDQGS---TVYNLGNGAGYSVMEVIHSVERVSGLTVPMRIEARRPGDP 298
Query: 180 SAMWADTSLAKEELGWSTQL-TIEEMCTDFWRWQTMNPDGY 219
+ + A + E GW+ + ++++ W+ +P G+
Sbjct: 299 AVLVASAEKIRRETGWTPRFPALDDIVATALAWRRAHPQGF 339
>UniRef50_UPI000023E28B Cluster: hypothetical protein FG07983.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07983.1 - Gibberella zeae PH-1
Length = 885
Score = 139 bits (337), Expect = 5e-32
Identities = 76/185 (41%), Positives = 103/185 (55%), Gaps = 21/185 (11%)
Query: 27 ITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFL 86
+T+ Y +KYF E +L D++ D W+II+LRYFNP+G PSG +GEDP TNL P +
Sbjct: 220 LTSPYRCSKYFCEAVLADIAYTDPSWHIIALRYFNPIGCDPSGPLGEDPKGIPTNLFPVI 279
Query: 87 AQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGT 146
AQV T IRD+IHV DLA GHVAAL+ S + +NLGT
Sbjct: 280 AQVL-------------------TAIRDFIHVTDLARGHVAALS--SDIESPFRTFNLGT 318
Query: 147 GKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCT 206
G G +V E V E + + + V RR+GD+ A AK+ELGW+ + TI++
Sbjct: 319 GNGTTVAEAVKSLEGASLKNIAVNLVPRRIGDVGFCVAANDRAKKELGWTAKETIQQFAK 378
Query: 207 DFWRW 211
D W +
Sbjct: 379 DLWNY 383
>UniRef50_Q8RGC6 Cluster: UDP-glucose 4-epimerase; n=2;
Fusobacterium nucleatum|Rep: UDP-glucose 4-epimerase -
Fusobacterium nucleatum subsp. nucleatum
Length = 324
Score = 139 bits (336), Expect = 6e-32
Identities = 85/213 (39%), Positives = 114/213 (53%), Gaps = 7/213 (3%)
Query: 1 MVFSSSCTVYGE-PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
++FSS+ VYGE E PI E H T I N YG +K E +++D + A N RY
Sbjct: 113 IIFSSTAAVYGEITEDNPIDEKHSTIPI-NPYGASKLMSERIIRDCAKAYGL-NYSIFRY 170
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN GAH IG+ T+L+ Q A +L VFG D+ T DGTGIRDYIHV+
Sbjct: 171 FNVAGAHEKYPIGQKGAG-VTSLITLTLQAAKDSNRILEVFGDDFPTKDGTGIRDYIHVV 229
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DL HV +L LL + ++NLG G G SV E V +VT ++ K RR GD
Sbjct: 230 DLVKAHVLSLKLLFKN--ESNIFNLGNGNGFSVLETVEAARKVTNKEIICKIAARRKGDP 287
Query: 180 SAMWADTSLAKEELGWSTQLT-IEEMCTDFWRW 211
+ + A + AK+ LGW Q T +E++ W +
Sbjct: 288 ACVIASSEKAKKILGWKAQYTNVEKIIETGWHF 320
>UniRef50_Q65D61 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 331
Score = 139 bits (336), Expect = 6e-32
Identities = 83/228 (36%), Positives = 129/228 (56%), Gaps = 12/228 (5%)
Query: 1 MVFSSSCTVYGEPEHLPITE-THPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+VF+SS VYG PE LP+TE T P + +G+ K+ +E+ML + A +I LR
Sbjct: 111 IVFASSAAVYGSPEDLPVTEETEPEP--VHAHGKVKWMMEKMLMEAEKAYGLKYVI-LRS 167
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN GAHPS +IGED E T+L+ + + ALG P + + ++ DGTG+RDY+HV
Sbjct: 168 FNACGAHPSAIIGEDRGSE-THLISNVLRTALGHLPFVHIDQSE----DGTGVRDYVHVQ 222
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAK-VPLKYVDRRLGD 178
DLA HV A+N L + ++YNL G+ S ++++ + VT + K + +
Sbjct: 223 DLAEAHVLAINHLRKGK-DSRIYNLSYGESYSAEQIILAAQYVTGIPLIAAKLTETDIDS 281
Query: 179 ISAMWADTSLAKEELGWSTQ-LTIEEMCTDFWRWQTMNPDGYPKKTKK 225
+ A +S A++ELGW+ Q ++ + D W W + NP+GY + K
Sbjct: 282 QATFAASSSRARKELGWTPQHNSLIAIIRDAWNWHSANPNGYASEKVK 329
>UniRef50_A6QU99 Cluster: UDP-glucose 4-epimerase; n=1; Ajellomyces
capsulatus NAm1|Rep: UDP-glucose 4-epimerase -
Ajellomyces capsulatus NAm1
Length = 286
Score = 139 bits (336), Expect = 6e-32
Identities = 62/133 (46%), Positives = 82/133 (61%)
Query: 87 AQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGT 146
A VA GK+ L V+G DY + DGT IRDYIH++DLA+GH+ ALN L + H ++ +NLGT
Sbjct: 138 ATVATGKREKLLVYGDDYASHDGTAIRDYIHILDLAAGHLQALNYLRENHPGVRAWNLGT 197
Query: 147 GKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCT 206
GKG +V ++ F +P + V RR GD+ + + S A ELGW T+EE C
Sbjct: 198 GKGSTVFHMIKAFSAAVGRDLPYEVVGRRAGDVLDLTGNPSRANRELGWKATRTLEEACE 257
Query: 207 DFWRWQTMNPDGY 219
D WRW NP GY
Sbjct: 258 DLWRWTKNNPAGY 270
>UniRef50_A1SPC3 Cluster: UDP-glucose 4-epimerase precursor; n=2;
Propionibacterineae|Rep: UDP-glucose 4-epimerase
precursor - Nocardioides sp. (strain BAA-499 / JS614)
Length = 334
Score = 138 bits (334), Expect = 1e-31
Identities = 81/218 (37%), Positives = 123/218 (56%), Gaps = 13/218 (5%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSS ++Y + ++E + Y RTK +EE+L+D+SAA D II LRYF
Sbjct: 112 VLFSSSASIYALKDDFEVSEGDRLEP-ASPYARTKRMMEEVLQDMSAATDLRAII-LRYF 169
Query: 61 NPVGAHP---SGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
NP+G+ P SG+ ++P+ +++ L A G+K T+ GTD+ T DGTGIRDYIH
Sbjct: 170 NPIGSDPDLESGIYAKEPS----HVLGQLVMAARGQKDAFTITGTDHPTRDGTGIRDYIH 225
Query: 118 VMDLASGHVAAL----NLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVD 173
V DLA HV A+ ++ + N+GTG GV+V+ELV F+ V +VP++
Sbjct: 226 VWDLARAHVRAVERFDEVIDAAGEPSVIINVGTGSGVTVRELVTAFQNVFGQEVPVREAP 285
Query: 174 RRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
R GD +A+ + L W T+L++E+ W
Sbjct: 286 PRPGDAVGAFANVDRSGRLLDWRTELSLEDAIASALAW 323
>UniRef50_UPI00015BC7D2 Cluster: UPI00015BC7D2 related cluster; n=1;
unknown|Rep: UPI00015BC7D2 UniRef100 entry - unknown
Length = 323
Score = 135 bits (327), Expect = 8e-31
Identities = 78/212 (36%), Positives = 115/212 (54%), Gaps = 5/212 (2%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+FSS+ VYG P+ ET IT YG+ K E++L+D+S D +++RYFN
Sbjct: 112 IFSSTAAVYGIKSDKPVKETDSIEPITP-YGQAKANFEKVLEDVSRVSDL-KYVAIRYFN 169
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA P G +G+ +K+ T+L+ + A G+ ++GTDYNT DGT IRDYIHV DL
Sbjct: 170 VAGADPEGELGQI-SKKPTHLILRALKAAKGEIKDFGIYGTDYNTKDGTCIRDYIHVSDL 228
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
H A+ L + + V+N G G+G+SVKE+V++ + VT P+ DRR GD
Sbjct: 229 VDAHFEAMRYLEEGG-KSDVFNCGYGRGLSVKEVVDIVKEVTGVDFPVYNYDRRPGDPPV 287
Query: 182 MWADTSLAKEELGWSTQLTIEE-MCTDFWRWQ 212
+ A+ K GW + + W W+
Sbjct: 288 LIANVDKIKNTFGWKPKYDDPYFIVKTAWEWE 319
>UniRef50_Q8G3T3 Cluster: UDP-glucose 4-epimerase; n=5;
Actinobacteridae|Rep: UDP-glucose 4-epimerase -
Bifidobacterium longum
Length = 337
Score = 132 bits (318), Expect = 1e-29
Identities = 84/221 (38%), Positives = 116/221 (52%), Gaps = 14/221 (6%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLR 58
+VFSSS YG P + E N YG+TK F E M + A + + I +LR
Sbjct: 115 LVFSSSAATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMAR---ACEQPFGIRFCALR 171
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLA-QVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
YFN G P L EDP NL+P L ++ GK P +FG DY TPDGT +RDYIH
Sbjct: 172 YFNVAGCGPVEL--EDPA--ILNLIPMLFNRLKQGKAPA--IFGDDYPTPDGTCVRDYIH 225
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V DLA H+AAL L + + +N+GTG+G SV+++V+ ++VT + RR G
Sbjct: 226 VSDLADAHIAALKYLDRDKRKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAG 285
Query: 178 DISAMWADTSLAKEELGWSTQLTIEEMCTDFW-RWQTMNPD 217
D + EE+GW + +E++ W WQ NP+
Sbjct: 286 DPPHLIGSPKRINEEMGWHAKYDVEDIVKSAWDAWQA-NPE 325
>UniRef50_A3ERM8 Cluster: UDP-glucose 4-epimerase; n=1;
Leptospirillum sp. Group II UBA|Rep: UDP-glucose
4-epimerase - Leptospirillum sp. Group II UBA
Length = 323
Score = 132 bits (318), Expect = 1e-29
Identities = 80/209 (38%), Positives = 115/209 (55%), Gaps = 7/209 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ SS+ VY PITE N YG TK E +++ A ++I RYF
Sbjct: 112 LILSSTAAVYSPKSDGPITEEDRIDP-QNPYGETKAAAERLVEACRHAFGVSSVI-FRYF 169
Query: 61 NPVGAHPS-GLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N PS GL+ + ++L+P + G+ P L VFG DY TPDGTG+RDYIHVM
Sbjct: 170 NAAALEPSYGLVSHAIPR--SHLIPAVLDAISGRIPALRVFGNDYPTPDGTGVRDYIHVM 227
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DLA H+ AL L + I +NLGTG+G SV +++ E+VT KVP + RR GD+
Sbjct: 228 DLAEAHLVALKRLLKGEIS-GTFNLGTGQGHSVLDVIRTAEKVTGKKVPYRIEARRPGDV 286
Query: 180 SAMWADTSLAKEELGW-STQLTIEEMCTD 207
S + A + A++ L W ++ ++E + D
Sbjct: 287 SMLVASGTRARQTLPWFPSRSSLERIMED 315
>UniRef50_Q9L047 Cluster: UDP-glucose 4-epimerase; n=7;
Actinomycetales|Rep: UDP-glucose 4-epimerase -
Streptomyces coelicolor
Length = 326
Score = 128 bits (310), Expect = 9e-29
Identities = 81/217 (37%), Positives = 111/217 (51%), Gaps = 8/217 (3%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSSS VYG P+ +TE P ++ YG TK E +++ A SLRYFN
Sbjct: 113 VFSSSAAVYGMPDVDLVTEETPCVPMSP-YGETKLAGEWLVRATGRATGLATA-SLRYFN 170
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA L+ NL+P + + L + +FG DY TPDGT +RDYIHV+DL
Sbjct: 171 VAGAASPDLVDTG----VYNLVPMVFE-KLTESAAPRIFGDDYATPDGTCVRDYIHVVDL 225
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A HVAA L + N+G G+GVSV+E+++ VT P RR GD +
Sbjct: 226 AEAHVAAARALQSSPGTALTLNIGRGEGVSVREMIDRINAVTGCDQPPTVTPRRPGDPAR 285
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWR-WQTMNPD 217
+ A A ELGW + +E+M T W W ++P+
Sbjct: 286 VVASADRAAVELGWKAKYDVEDMITSAWAGWVRLHPE 322
>UniRef50_Q6KI97 Cluster: Udp-glucose 4-epimerase; n=1; Mycoplasma
mobile|Rep: Udp-glucose 4-epimerase - Mycoplasma mobile
Length = 330
Score = 128 bits (309), Expect = 1e-28
Identities = 73/214 (34%), Positives = 117/214 (54%), Gaps = 5/214 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSS+ VYG+ +LPI E I N YG +K E++++D + +D + LRYF
Sbjct: 113 LIFSSTAAVYGQKSNLPIREDEDLNPI-NPYGSSKQMSEKIIQDYAHVND-FKFAILRYF 170
Query: 61 NPVGAHPSGLIGEDPTK--EFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N GAH + IG P K + ++L+P ++ + L +FG +Y+T DGT IRDYIHV
Sbjct: 171 NVAGAHQNNSIGLVPKKGHKVSHLIPSISSFVFNELDSLKIFGNNYDTKDGTCIRDYIHV 230
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
DLA H A + + L + N+G+ KG SV E+V FE+ K+ + +R GD
Sbjct: 231 QDLAHAHFLAAKYIFENKTNL-IVNVGSEKGFSVLEVVKTFEKQLNKKLNYEINPKRDGD 289
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
+ + A T+ + L + + ++EE+ W+
Sbjct: 290 PAFLVASTTKIAKILNFKPKFSLEEIVKTELAWR 323
>UniRef50_A3VS38 Cluster: UDP-glucose 4-epimerase; n=2;
Alphaproteobacteria|Rep: UDP-glucose 4-epimerase -
Parvularcula bermudensis HTCC2503
Length = 328
Score = 128 bits (308), Expect = 2e-28
Identities = 77/195 (39%), Positives = 106/195 (54%), Gaps = 6/195 (3%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSS+ +VYG P+ +PI E P I+ +G E ++ D+ I LRYFN
Sbjct: 113 VFSSTASVYGVPQRMPIREETPLSPISP-FGAAMGMAERIVADVCRPACIGTAI-LRYFN 170
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGK-KPVLTVFGTDYNTPDGTGIRDYIHVMD 120
GA P+ GE T +L+ AQ+A G L ++G DYNTPDGT IRDYIHV D
Sbjct: 171 VAGADPNARAGE--TGHPRHLIKAAAQIATGVLNEPLKIYGNDYNTPDGTCIRDYIHVSD 228
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A H AL+ L + + N G G+G+SV E++ +RVT +P +Y RR GD
Sbjct: 229 MAEAHATALDHLMAGGGSVTL-NCGYGRGISVHEVIAAVQRVTGKTLPTQYAARRQGDAP 287
Query: 181 AMWADTSLAKEELGW 195
+ ADT+ + L W
Sbjct: 288 LLIADTAAIRTALSW 302
>UniRef50_P72903 Cluster: UDP-glucose-4-epimerase; n=20;
Bacteria|Rep: UDP-glucose-4-epimerase - Synechocystis
sp. (strain PCC 6803)
Length = 340
Score = 125 bits (301), Expect = 1e-27
Identities = 72/196 (36%), Positives = 112/196 (57%), Gaps = 4/196 (2%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSS+ VYG PI+E I N YGR+K E +++D + + +I LRYF
Sbjct: 117 LIFSSTAAVYGNSSSNPISEAEIPCPI-NPYGRSKLASEWIIQDYAKSSALQYVI-LRYF 174
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA P G +G+ +K T+L+ + L KP L +FGTD+ T DGT +RDYIHV D
Sbjct: 175 NVAGADPEGRLGQ-MSKTTTHLVRSVCDAILNLKPSLDIFGTDFPTRDGTAVRDYIHVED 233
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA H+ AL L + ++ N G G+G SV+E+V+ + ++ ++ +RRLGD +
Sbjct: 234 LAKAHLDALRYL-ENGGESQILNCGYGQGYSVREVVDRAKAISGVDFLVRETERRLGDPA 292
Query: 181 AMWADTSLAKEELGWS 196
++ A ++ L W+
Sbjct: 293 SVIACADSIRQVLNWT 308
>UniRef50_A4AI37 Cluster: Putative UDP-glucose 4-epimerase; n=1;
marine actinobacterium PHSC20C1|Rep: Putative
UDP-glucose 4-epimerase - marine actinobacterium
PHSC20C1
Length = 322
Score = 124 bits (299), Expect = 2e-27
Identities = 79/212 (37%), Positives = 117/212 (55%), Gaps = 13/212 (6%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLR 58
+VFSSS VYGE I E T I N YG TK E+++ SA+ W + SLR
Sbjct: 110 LVFSSSAAVYGEASGA-IAEDATTNPI-NPYGATKLVGEQLI---SASSLAWPLRAASLR 164
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
YFN VG S +G+ + NL+P + KP L +FG DY+TPDGT +RDY+HV
Sbjct: 165 YFN-VGGAGSPELGDT---QALNLIPICFEQIAANKPPL-IFGEDYDTPDGTCVRDYVHV 219
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+A H+A L+ L V N+GTG G +V+++V +V+ +++ +DRR GD
Sbjct: 220 SDVAEAHLAVLDAL-PAQPGNTVLNIGTGVGTTVRQMVEAILQVSGSELTATVLDRRTGD 278
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWR 210
+A+ +E GWS + T++++ W+
Sbjct: 279 PAAVVGIVDNIRELTGWSARFTVDDIVESAWQ 310
>UniRef50_Q6MS04 Cluster: UDP-glucose 4-epimerase; n=3; Mycoplasma
mycoides subsp. mycoides SC|Rep: UDP-glucose 4-epimerase
- Mycoplasma mycoides subsp. mycoides SC
Length = 334
Score = 124 bits (298), Expect = 3e-27
Identities = 74/207 (35%), Positives = 112/207 (54%), Gaps = 6/207 (2%)
Query: 2 VFSSSCTVYGE-PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
VFSSS VYG H + YGRTKYF EE++KD + A+ ++ LRYF
Sbjct: 114 VFSSSAAVYGNNSRHNGYFYEDDPKEPCSPYGRTKYFGEEIIKDFAIANPNFHYTFLRYF 173
Query: 61 NPVGAHPSGLIG---EDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
N GA S IG +D K T+L+P ++ A G ++FG+DYNT DGT IRDY++
Sbjct: 174 NVAGASKSKRIGYLTKDNNKP-THLIPAISYFAFGLTDQFSIFGSDYNTKDGTCIRDYVY 232
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V +LA H+ + + + L YN+G+GKG S E++ FE+ K+ + +R G
Sbjct: 233 VCELAELHLLTAQKMVKENCNL-YYNIGSGKGFSNLEIIKKFEKQLGYKLNIDIAPKRSG 291
Query: 178 DISAMWADTSLAKEELGWSTQLTIEEM 204
D + A + +EL + + I+++
Sbjct: 292 DPDVLVASNTKLCQELNYKIKTNIKDI 318
>UniRef50_A3Q712 Cluster: UDP-glucose 4-epimerase; n=6;
Actinobacteria (class)|Rep: UDP-glucose 4-epimerase -
Mycobacterium sp. (strain JLS)
Length = 329
Score = 122 bits (295), Expect = 6e-27
Identities = 77/220 (35%), Positives = 113/220 (51%), Gaps = 7/220 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSS +G P+ + E+ PT + YG TK E +L+D A + SLRYF
Sbjct: 112 IVFSSSAATFGTPDVDQVDESTPTAP-ESPYGETKLIGEWLLRDAGRASGLRHT-SLRYF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N VG+ + L P NL P + + L + + G DY TPDGT +RDY+ V D
Sbjct: 170 NVVGSGSTALFDTSPH----NLFPLVFDM-LYRGDTPRINGDDYPTPDGTCVRDYVDVGD 224
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A HVAA L+++ VYNLG+G G SV+E++ VT + + RR GD +
Sbjct: 225 VALAHVAAARRLTRSEPVEPVYNLGSGAGTSVREIMTAIRTVTGVDFEPQIMPRRPGDPA 284
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYP 220
+ A+ LA +L W + ++E+M W + YP
Sbjct: 285 RIVANGDLAARDLDWKMRHSLEDMVASAWAARQAAGAAYP 324
>UniRef50_Q7VJ63 Cluster: UDP-glucose 4-epimerase; n=30;
Epsilonproteobacteria|Rep: UDP-glucose 4-epimerase -
Helicobacter hepaticus
Length = 345
Score = 121 bits (292), Expect = 1e-26
Identities = 75/187 (40%), Positives = 103/187 (55%), Gaps = 12/187 (6%)
Query: 2 VFSSSCTVYGEPEH--LPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+FSS+ VYGEP +PI E P I N YG +K E +L D S A +N ++LRY
Sbjct: 122 IFSSTAAVYGEPHTSLIPIDENAPLLPI-NPYGSSKMMSERILYDTSLAFKNFNYVALRY 180
Query: 60 FNPVGAH----PSGLIGE----DPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTG 111
FN GA P L +K T+L+ + A GK+ +++FGTDY T DGT
Sbjct: 181 FNVAGASMDNTPQILSNHKGLGQRSKNATHLIKVACECACGKRESMSIFGTDYPTKDGTC 240
Query: 112 IRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY 171
IRDYIH+ DLAS H+ AL L T ++N+G KG SVKE+++V + ++ +
Sbjct: 241 IRDYIHIDDLASAHLEALTFLQHTQTS-NIFNVGYCKGYSVKEVIDVVKEISGMDFKVIE 299
Query: 172 VDRRLGD 178
RR GD
Sbjct: 300 SARREGD 306
>UniRef50_A0LJ03 Cluster: UDP-glucose 4-epimerase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: UDP-glucose
4-epimerase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 318
Score = 119 bits (286), Expect = 7e-26
Identities = 71/190 (37%), Positives = 108/190 (56%), Gaps = 6/190 (3%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VFSSSC YG I E HP TN YG +K E+++ ++ +LRYF
Sbjct: 111 LVFSSSCATYGNARTPTIKENHPQEP-TNPYGLSKLMCEQVISTVAPVAGI-RFAALRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N +G P G + E E T+++P L + L +++GT++ TPDGT +RDY++VMD
Sbjct: 169 NVIGGDPEGEVYERHEPE-THVLPNLMKAGLSGAE-FSLYGTNHPTPDGTAVRDYVYVMD 226
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
LA+ HV AL++L + RL + N+G G+G SV+EL+ + R KA++ + R GD
Sbjct: 227 LAAAHVKALDVL-RARDRL-ISNVGRGRGTSVRELLEIVRRNVKAELNVVEKPIRPGDPP 284
Query: 181 AMWADTSLAK 190
+ AD + K
Sbjct: 285 ELVADNTYLK 294
>UniRef50_Q4Q3V7 Cluster: Udp-glc 4'-epimerase, putative; n=7;
Trypanosomatidae|Rep: Udp-glc 4'-epimerase, putative -
Leishmania major
Length = 391
Score = 119 bits (286), Expect = 7e-26
Identities = 80/211 (37%), Positives = 113/211 (53%), Gaps = 24/211 (11%)
Query: 31 YGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVA 90
YG TK E MLKD +AA ++ LRYFN GA G IGE E ++L+P + +V
Sbjct: 180 YGTTKLVGEYMLKDCAAAYGIKSVC-LRYFNACGADAEGDIGETHEPE-SHLIPLILRVP 237
Query: 91 LGKK----------------PVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQ 134
L K +++FGTDY TPDGT IRDY+HV DL+S HV AL+ L++
Sbjct: 238 LADKINAYNAVHHPERQKVNGYVSIFGTDYPTPDGTCIRDYVHVKDLSSAHVRALDYLAK 297
Query: 135 THIRLK-----VYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLA 189
K +NLGT KG SV+E++ RVT +P + RR GD + A A
Sbjct: 298 LTPDDKDRFFSTFNLGTSKGYSVREVIEAARRVTGHPIPEREEKRRDGDPPVLVASGEEA 357
Query: 190 KEELGWSTQL-TIEEMCTDFWRWQTMNPDGY 219
LGW+ + +I+++ W++ + +P GY
Sbjct: 358 AAALGWTLEYESIDKIIESAWKFHSKHPVGY 388
>UniRef50_Q07GF0 Cluster: UDP-glucose 4-epimerase; n=1; Roseobacter
denitrificans OCh 114|Rep: UDP-glucose 4-epimerase -
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 342
Score = 117 bits (282), Expect = 2e-25
Identities = 66/161 (40%), Positives = 94/161 (58%), Gaps = 7/161 (4%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSS+C YG E ++E P + Y RTK +E M++D + A LRYF
Sbjct: 111 LLFSSTCATYGMAEADTMSEATPLDPFSP-YARTKLAVEWMIRDFAHAYGM-GFTLLRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N GA G GED T E ++L+P + QV LG++ + VFG DY TPDGT IRDY+H D
Sbjct: 169 NASGADADGRHGEDHTPE-SHLIPLVLQVPLGQRDKIMVFGDDYPTPDGTCIRDYVHTRD 227
Query: 121 LASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFE 160
LAS H+ A + T + +++N+GTG G SV +++ E
Sbjct: 228 LASAHLLA---IEATEVGTDEIFNIGTGNGQSVMQIIEACE 265
>UniRef50_Q2MFK2 Cluster: Putative apramycin biosynthetic
oxidoreductase 1; n=2; Actinomycetales|Rep: Putative
apramycin biosynthetic oxidoreductase 1 - Streptomyces
sp. DSM 40477
Length = 312
Score = 106 bits (255), Expect = 4e-22
Identities = 76/211 (36%), Positives = 112/211 (53%), Gaps = 17/211 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF SS VYG H P+ E+HPT T+VYG TK E+ + AA + +SLR F
Sbjct: 112 VVFLSSGAVYGPTGHAPVPESHPTAP-TSVYGATKLAAEQAV-GWYAATGAVSAVSLRLF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G+ G+ +D T L+ VA G+ P L V G DGT +RD++HV D
Sbjct: 170 NAAGSVRPGVGPDDST-----LVARALAVASGRSPALPVNG------DGTTVRDFVHVAD 218
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A A+ ++ R V+NLG SV+E+V E+VT +VP+++ D
Sbjct: 219 VADAVARAVATPARRPAR--VFNLGAVPA-SVREVVAAVEQVTGRRVPVEHGPPNPADQP 275
Query: 181 AMWADTSLAKEELGWSTQ-LTIEEMCTDFWR 210
+ ADT+ A+ +LGW+ + ++E M D WR
Sbjct: 276 WLAADTTAARRDLGWTPERSSLERMIEDQWR 306
>UniRef50_Q8TXF0 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=1; Methanopyrus kandleri|Rep:
Nucleoside-diphosphate-sugar epimerase - Methanopyrus
kandleri
Length = 309
Score = 105 bits (251), Expect = 1e-21
Identities = 74/208 (35%), Positives = 107/208 (51%), Gaps = 22/208 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS VYGEPE+LP+ E HPT I+N YG +K E ++ + A D + + LRY N
Sbjct: 118 SSGGAVYGEPEYLPVDEEHPTRPISN-YGVSKLAGEYYVR-VYAERDGFEYVILRYANVY 175
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G +DP E + FL + A G+ LT+FG DG RD++ V D+A
Sbjct: 176 GPR------QDPRGEAGVIPIFLLRAARGEP--LTIFG------DGEQTRDFVFVEDVAR 221
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
A+ VYN+GTG+ SV ++VN + VT V + Y D R G++ ++
Sbjct: 222 VTAEAVERGDG------VYNIGTGRETSVNDIVNAVKAVTGVDVEVVYEDPRPGEVRRIY 275
Query: 184 ADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D S A+EELG+ ++ +EE W W
Sbjct: 276 LDPSRAREELGFEPRVDLEEGIERTWEW 303
>UniRef50_A4VWA8 Cluster: UDP-glucose 4-epimerase; n=1;
Streptococcus suis 05ZYH33|Rep: UDP-glucose 4-epimerase
- Streptococcus suis (strain 05ZYH33)
Length = 107
Score = 99.1 bits (236), Expect = 8e-20
Identities = 46/100 (46%), Positives = 65/100 (65%), Gaps = 1/100 (1%)
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D A G++ AL+ +S T + YNLG+ +G SV ELV FE+V V K VDRR GD+
Sbjct: 7 DCALGYIKALDTISTT-TGVYTYNLGSAQGTSVLELVKAFEKVNGVTVHYKLVDRRPGDV 65
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
+ +A+ A +EL W+T +T+E+MC D W WQ+ NP+GY
Sbjct: 66 ATCYANADKAWKELNWNTVITMEDMCQDTWYWQSKNPNGY 105
>UniRef50_Q6FB43 Cluster: Putative UDP-galactose 4-epimerase; n=2;
Acinetobacter|Rep: Putative UDP-galactose 4-epimerase -
Acinetobacter sp. (strain ADP1)
Length = 334
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/212 (27%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSI-TNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+V SS VYG+ +TE P ++ N Y +++ IEE+++D D +W I LR
Sbjct: 118 LVHLSSLMVYGKSSS-KLTEDEPFDTVYPNPYIKSQQMIEEIIRDTFKTDHEWKIAILRL 176
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N GA G++GE T+ N++P QVA ++ L + +T D T R ++HV+
Sbjct: 177 SNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLEL-QRQADTTDQTVERSFLHVL 235
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ A+L L+Q + +N+ + S+++L+ V +VT+ ++ ++
Sbjct: 236 DVCEAVFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEEL 295
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ + A+ AK+ L W + T+++M W++
Sbjct: 296 AQVGANIDKAKQVLNWQPKRTLQQMIEHQWQF 327
>UniRef50_P47364 Cluster: UDP-glucose 4-epimerase; n=4;
Mycoplasma|Rep: UDP-glucose 4-epimerase - Mycoplasma
genitalium
Length = 340
Score = 93.5 bits (222), Expect = 4e-18
Identities = 66/216 (30%), Positives = 116/216 (53%), Gaps = 19/216 (8%)
Query: 1 MVFSSSCTVYGEP------EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI 54
+ F+SS VYG+ E + ITET T N YG +K F++E++ + A + + +
Sbjct: 122 LFFASSAAVYGQTTNSYISEEIVITETQAT----NPYGLSK-FLDELILNAVAKNSQLQV 176
Query: 55 ISLRYFNPVGAH-PSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIR 113
+ LR+FN GA P G + T L+P L + L + P ++G DY T DG+ IR
Sbjct: 177 VCLRFFNVAGAILPFGNFNGNTTL----LIPNLVKAFLKQTPFF-LYGNDYATKDGSCIR 231
Query: 114 DYIHVMDLASGHVAALNLLS-QTHIRLKVYNLGTGKGVSVKELVNVFERV-TKAKVPLKY 171
DYIHV D+ + H L+ I+ + +NLG+G G S E++++ ++V +++ L+
Sbjct: 232 DYIHVYDICNAHFLLWKWLNDHRQIKFETFNLGSGIGTSNLEVIDIAKKVFYPSRLNLEI 291
Query: 172 VDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTD 207
+R D + + A+ + AK+ + +++M +D
Sbjct: 292 RPKRSWDPAILVANVAKAKQTFQFKITRNLKDMISD 327
>UniRef50_Q2JEQ1 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Frankia|Rep: NAD-dependent epimerase/dehydratase -
Frankia sp. (strain CcI3)
Length = 334
Score = 89.4 bits (212), Expect = 7e-17
Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 19/212 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VF S+C VYG + I ET P N YG +K+ E +L A + LR FN
Sbjct: 117 VFGSTCAVYGNVDLARIPETCPPDP-ANPYGTSKFAAERLLSH-QAGTGLLGAVILRSFN 174
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
GA +G I D ++ ++P VA G + V V G DG +R+Y+HV+D+
Sbjct: 175 VAGA-VAGHIDRDGSR----IIPAAIAVASGCRDVFRVNG------DGLALREYVHVVDM 223
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVD-RRLGDIS 180
A+ ++ AL H V+N+G+G GVSV +++ RV A P++ V + +
Sbjct: 224 ATAYLTALVAARPGH--CAVFNVGSGVGVSVTDVLAAVGRV--AGRPVRRVHCPPVSEPR 279
Query: 181 AMWADTSLAKEELGWSTQL-TIEEMCTDFWRW 211
+ D++ + +LGWS+ +I+ + D WRW
Sbjct: 280 TLIGDSTRIRADLGWSSPASSIDRIVADAWRW 311
>UniRef50_A7DQX9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
NAD-dependent epimerase/dehydratase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 308
Score = 84.6 bits (200), Expect = 2e-15
Identities = 66/202 (32%), Positives = 100/202 (49%), Gaps = 19/202 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+ +SS VYG P+ +P+TE ++ YG K +E L+ A N I+LR+FN
Sbjct: 114 IAASSAAVYGNPKQIPVTEFTIPNPVSP-YGADKIALEFYLRAFCNAYGI-NGIALRFFN 171
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G S TK FL Q+ K L +FG DG RD+IH+ DL
Sbjct: 172 VYGLGQSNAYAGVITK-------FLNQIHQTKP--LRIFG------DGKNTRDFIHIDDL 216
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
G +++ +S R VYNL +GK VSVKEL + ++ K+ +KY R GD+
Sbjct: 217 VMGIEQSISNISGK--RGSVYNLASGKSVSVKELAKLMLEISDKKLEIKYESPRKGDLLY 274
Query: 182 MWADTSLAKEELGWSTQLTIEE 203
A LAK +L + ++++++
Sbjct: 275 SSASIDLAKNDLSFVPKISLKD 296
>UniRef50_Q2RMP3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: NAD-dependent
epimerase/dehydratase - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 319
Score = 83.0 bits (196), Expect = 6e-15
Identities = 66/205 (32%), Positives = 97/205 (47%), Gaps = 18/205 (8%)
Query: 1 MVFSSSC-TVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
++F+SS TVYG + +P E H IT YG +K +E L A + R
Sbjct: 109 LIFASSGGTVYGRLKRIPAEEHHSLAPIT-AYGASKACVELYL-GFYRAHHGMDCRVARI 166
Query: 60 FNPVGAHPSGLIGEDPT-KEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
NP GA G+D K+ FL + G++ +T++G DG+ IRDYIH+
Sbjct: 167 SNPFGA------GQDARRKQQGAASAFLFKALAGEE--ITIWG------DGSVIRDYIHI 212
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
DL G +A + H L +YNLG+G G+S+ E+V + Y+ R D
Sbjct: 213 ADLTRGLIALSDASLADHHDLPIYNLGSGVGISLNEIVETLRNRLGLTATVNYLPSRNFD 272
Query: 179 ISAMWADTSLAKEELGWSTQLTIEE 203
I A D +K+ L WS Q++ E
Sbjct: 273 IPASILDIRKSKDLLEWSPQMSFAE 297
>UniRef50_Q4AGU6 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Chlorobium phaeobacteroides BS1
Length = 304
Score = 83.0 bits (196), Expect = 6e-15
Identities = 66/210 (31%), Positives = 103/210 (49%), Gaps = 24/210 (11%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS TVYG P +P+ E +PT + YG TK IE+ L L N + +R NP
Sbjct: 113 SSGGTVYGIPTEIPVHENNPTNPECS-YGITKLVIEKYLA-LFKHLYGLNYVIVRPSNPY 170
Query: 64 GA--HPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G +P+ + G P FL +VA G+ + ++G DG +RDYI + DL
Sbjct: 171 GERQNPNSIQGAIPV--------FLNKVAKGES--IDIWG------DGEVVRDYIFIDDL 214
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
G A + +Q+ I +NLG+ G S+ +V + ++T +V +KY +R DI
Sbjct: 215 VDGIYKAATVKAQSCI----FNLGSSTGYSLNYIVKIIRQITGRQVEIKYKAKRTFDIPE 270
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
++ D S A +EL W+ ++E W +
Sbjct: 271 IYLDISRAGKELSWAPVTSLESGIEKTWEF 300
>UniRef50_Q5V6W4 Cluster: UDP-glucose 4-epimerase; n=1; Haloarcula
marismortui|Rep: UDP-glucose 4-epimerase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 309
Score = 83.0 bits (196), Expect = 6e-15
Identities = 67/204 (32%), Positives = 99/204 (48%), Gaps = 22/204 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG P+ +PI E PT + YG KY E+ + + + LRYF
Sbjct: 116 VVFASSAAVYGVPDDVPIGEDAPTEP-NSPYGFEKYLGEQYAR-FYTEEYGLPTVPLRYF 173
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G P GL GE + ++ + A +P LTV G DGT RD++HV D
Sbjct: 174 NVYG--PRGLDGE-----YAGVIGTFVRQAQAGEP-LTVEG------DGTQTRDFVHVDD 219
Query: 121 LASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
V NLL+ T + + +N+GTG+ +S+ EL V + +++V R DI
Sbjct: 220 -----VVRANLLAATTDAIGRPFNVGTGRSISINELAETVRDVVGTDIAVEHVPGRANDI 274
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
AD A+E LG+ L + +
Sbjct: 275 QQSEADLGDARELLGYEPSLPLRK 298
>UniRef50_A4WHT4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Pyrobaculum arsenaticum DSM 13514|Rep: NAD-dependent
epimerase/dehydratase - Pyrobaculum arsenaticum (strain
DSM 13514 / JCM 11321)
Length = 299
Score = 83.0 bits (196), Expect = 6e-15
Identities = 69/209 (33%), Positives = 100/209 (47%), Gaps = 24/209 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V+ SS VYG P + PI E HPT T+ YG +K EE L L +A K+ + R F
Sbjct: 106 LVYLSSAAVYGNPVYTPIDEEHPTRP-TSPYGLSKLAGEEALALLQSAGLKYAV--ARLF 162
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +G TK F+ + G PV +FG+ G RD+IHV+D
Sbjct: 163 NVYGPGQTGPYAGVITK-------FIERARAGLPPV--IFGS------GEQTRDFIHVLD 207
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A + +Q V+N+GTG+ VS+KEL + ++ Y R GDI+
Sbjct: 208 VARFVETLVEKGAQ-----GVFNVGTGRAVSIKELAHAVMKLAGIGGEPIYASPRPGDIA 262
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFW 209
A+ A+ LGW ++T+EE W
Sbjct: 263 HSVANIKKAR-GLGWEPKITLEEGLAQLW 290
>UniRef50_Q57664 Cluster: Putative UDP-glucose 4-epimerase; n=3;
cellular organisms|Rep: Putative UDP-glucose 4-epimerase
- Methanococcus jannaschii
Length = 305
Score = 81.4 bits (192), Expect = 2e-14
Identities = 65/216 (30%), Positives = 104/216 (48%), Gaps = 24/216 (11%)
Query: 1 MVFSSSC-TVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+VF+SS VYGEP +LP+ E HP + + YG +KY EE +K + I LRY
Sbjct: 110 IVFASSGGAVYGEPNYLPVDENHPINPL-SPYGLSKYVGEEYIKLYNRLYGIEYAI-LRY 167
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP E + F+ ++ + P+ +FG DG RD+++V
Sbjct: 168 SNVYGER------QDPKGEAGVISIFIDKMLKNQSPI--IFG------DGNQTRDFVYVG 213
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+A ++ ALN ++ + N+GTGK SV EL ++ + + Y R G++
Sbjct: 214 DVAKANLMALNWKNE------IVNIGTGKETSVNELFDIIKHEIGFRGEAIYDKPREGEV 267
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
++ D A E LGW ++ ++E W N
Sbjct: 268 YRIYLDIKKA-ESLGWKPEIDLKEGIKRVVNWMKNN 302
>UniRef50_A6GLY7 Cluster: Putative uncharacterized protein; n=1;
Limnobacter sp. MED105|Rep: Putative uncharacterized
protein - Limnobacter sp. MED105
Length = 294
Score = 79.8 bits (188), Expect = 5e-14
Identities = 59/214 (27%), Positives = 102/214 (47%), Gaps = 20/214 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG P++ET G + YG K E+ +L A N + +R+F
Sbjct: 99 IVFASSAAVYGNRHSYPVSETM-AGQPISPYGLHKLMCEQHA-ELFANLYNVNSVGMRFF 156
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP+ ++ ++ F+ ++ G P T++G DG+ RD+++V
Sbjct: 157 NVYGPR------QDPSSPYSGVISIFIDRLRRGLAP--TIYG------DGSQTRDFVYVG 202
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ + A+N Q YN+G G+ V++ L + V +P K R G+I
Sbjct: 203 DVVQALIKAMNSKKQG---FAAYNVGRGESVTINMLWQILCDVVGTNLPAKLGPAREGEI 259
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQT 213
A+ S + ELG+ ++T++E + W T
Sbjct: 260 HTSLANISKIEAELGYKAEITLQEGLIKTYEWAT 293
>UniRef50_A0RWB8 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=1; Cenarchaeum symbiosum|Rep:
Nucleoside-diphosphate-sugar epimerase - Cenarchaeum
symbiosum
Length = 299
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/202 (32%), Positives = 102/202 (50%), Gaps = 22/202 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V++SS ++YG+ LPI E +T YG TK E+L D A+ I+SLRYFN
Sbjct: 107 VWASSSSIYGDATSLPIGEDSVRDPVTP-YGETKAQ-GEVLADKYASMGA-RIVSLRYFN 163
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G S T F ++ GK PV +FG DG+ RDY+HV D+
Sbjct: 164 VYGRGQSAAYAGVITG-------FYNRIESGKPPV--IFG------DGSHTRDYVHVEDV 208
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A ++ A+ + + N+GTG SV EL + +++ A + ++ D +++
Sbjct: 209 ARANLMAMESPADSCS----INIGTGIETSVLELARMMIKLSGADLEPEFADPPGDEVAF 264
Query: 182 MWADTSLAKEELGWSTQLTIEE 203
ADT+LA++ +GWS + +EE
Sbjct: 265 SRADTALARQLIGWSHSIELEE 286
>UniRef50_A1VG42 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep:
NAD-dependent epimerase/dehydratase - Desulfovibrio
vulgaris subsp. vulgaris (strain DP4)
Length = 316
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/210 (30%), Positives = 102/210 (48%), Gaps = 24/210 (11%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLRYFN 61
SS +YG+ I+E+HPT + + YG K +E K L+ + + I +LR N
Sbjct: 120 SSGGAIYGKHLMPRISESHPTDPLCS-YGIVKLAVE---KYLALYHELYGIDYAALRISN 175
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
P G P G + + FL ++ L +P L V+G DG+ +RDYI+V D+
Sbjct: 176 PFG--PLQRAGAEQGV----IGVFLGRI-LRNEP-LHVWG------DGSVVRDYIYVEDV 221
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A V A + ++ H V+N+G+G G+S+ E++ + VT V +KY R D+
Sbjct: 222 ARALVLAARMKTEHH----VFNIGSGAGLSLNEIIGMMRSVTGRDVVVKYDQNRAFDVPY 277
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D S A +EL W + +E W W
Sbjct: 278 SVLDVSRALDELDWKASIAFDEGLRRTWEW 307
>UniRef50_Q1Q482 Cluster: Similar to dTDP-glucose 4,6-dehydratase;
n=2; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
dTDP-glucose 4,6-dehydratase - Candidatus Kuenenia
stuttgartiensis
Length = 319
Score = 77.4 bits (182), Expect = 3e-13
Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 20/200 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
S+ VYGEP+ LP E+ P +++ YG +K+ +E L D N+ LRY N
Sbjct: 116 STGGAVYGEPKQLPANESTPPEPLSH-YGVSKHTVEHYLHVFHKLYDL-NVTILRYPNVY 173
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G S P E + F + K+P T+FG DG+ RDY++V D+
Sbjct: 174 GPRQS------PHGEAGVVAIFSELMLQNKQP--TIFG------DGSKTRDYVYVDDIVK 219
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
++A L + I YNLG GK +S E+ R + + +R G++ +
Sbjct: 220 ANIAVLGDIGNGEI----YNLGWGKEISDMEVFLAVRRALRKDIEPILGQKRHGEVDHIS 275
Query: 184 ADTSLAKEELGWSTQLTIEE 203
D S A+ E+ WS ++T EE
Sbjct: 276 LDHSKARREIKWSPEVTFEE 295
>UniRef50_Q20YR4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodopseudomonas palustris BisB18|Rep: NAD-dependent
epimerase/dehydratase - Rhodopseudomonas palustris
(strain BisB18)
Length = 345
Score = 76.6 bits (180), Expect = 5e-13
Identities = 61/203 (30%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIE---EMLKDLSAADDKWNIISLRYF 60
SS TVYG + +P+ ETH IT YG +K E + +DL D + R
Sbjct: 142 SSGGTVYGRLQCVPVPETHALAPIT-AYGASKAAAELYFNVYRDLHGIDAR----IARIA 196
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP G G++P + + + AL + V ++G DG+ +RD+IH+ D
Sbjct: 197 NPFGP------GQNPRRP-QGVASTITYRALAGEAV-EIWG------DGSVVRDFIHISD 242
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
SG +A + + L YN+G+GKG SV+E+V + ER + ++ R D+
Sbjct: 243 AVSGLLAVADAKPTSPHILPTYNIGSGKGASVREIVAMVERHLGRPIAIEKKPERAFDVP 302
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
D S A ELGW + +++
Sbjct: 303 TSVLDISRATTELGWRPAVELDQ 325
>UniRef50_Q6I4D4 Cluster: UDP-glucose 4-epimerase, C-terminus; n=10;
Bacillus cereus group|Rep: UDP-glucose 4-epimerase,
C-terminus - Bacillus anthracis
Length = 257
Score = 75.8 bits (178), Expect = 9e-13
Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 22/198 (11%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLRYFN 61
SS TVYGEPE+LPI E HP ++ YG TK +E L K+ I + RY N
Sbjct: 59 SSGGTVYGEPEYLPIDEDHPLKPLSP-YGITKVSLENYLYFYKK---KYGIDYVVCRYSN 114
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
P G + ++P K+ + FL Q ++ + ++G IRDYI++ DL
Sbjct: 115 PYGKY------QNPLKKVGAINCFLYQHLSNER--INIYGNPQEI-----IRDYIYIDDL 161
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+ L ++ VYN+G+GKG+S+K ++ E++T+ KV ++ ++
Sbjct: 162 VE---ITIQLSQLNRLKSCVYNIGSGKGLSLKRIIVELEKLTERKVDFICYKQKQENVQK 218
Query: 182 MWADTSLAKEELGWSTQL 199
+ + + E W ++
Sbjct: 219 IILNIDRVRRECNWEPKV 236
>UniRef50_Q1V1Y0 Cluster: UDPglucose 4-epimerase; n=2; Candidatus
Pelagibacter ubique|Rep: UDPglucose 4-epimerase -
Candidatus Pelagibacter ubique HTCC1002
Length = 318
Score = 75.8 bits (178), Expect = 9e-13
Identities = 59/199 (29%), Positives = 103/199 (51%), Gaps = 14/199 (7%)
Query: 2 VFSSSCTVYGEPEHL-PITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+FSSS VYGE + P+ E + ++ YG +K E +++ +N I LRYF
Sbjct: 113 IFSSSAAVYGEVKTFKPLAENFIL-TPSSPYGISKMKGEMLIRKKKY----FNSIILRYF 167
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGK-KPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G ++ K + +L+ L ++ + K + + G +Y+T DGT +RD++HV
Sbjct: 168 NVAGPTFDNKFRQN-FKSYKHLLKKLNEINFSRNKNIFKINGKNYDTIDGTCVRDFVHVQ 226
Query: 120 DLASGHVAALNLLSQTHIRLKVY----NLGTGKGVSVKELVNVFERVTKAKVPLKYVDRR 175
D+A ++ +L+S I Y N G+GK SV ++V F+ ++K + + R
Sbjct: 227 DIA--NINYRSLISIKKILKNDYSLTLNCGSGKENSVLQIVKKFKIISKKNFKIIFTKPR 284
Query: 176 LGDISAMWADTSLAKEELG 194
+GD + +D L K++LG
Sbjct: 285 IGDPPFLLSDNRLFKKKLG 303
>UniRef50_A0FWU5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Betaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase - Burkholderia phymatum STM815
Length = 310
Score = 75.8 bits (178), Expect = 9e-13
Identities = 65/200 (32%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD-KWNIISLRYFNP 62
SS TVYG+P +LPI E HPT + YG TK IE+ L K NI LR NP
Sbjct: 116 SSGGTVYGDPVYLPIDEKHPTNPKVS-YGITKLAIEKYLLLYQYQHGIKANI--LRVANP 172
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G + F + AL K+P ++G DGT RDY+++ D+A
Sbjct: 173 YGERQRVETAQGAIAVFLDK-------ALRKQP-FEIWG------DGTVTRDYLYIGDVA 218
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
A+ Q V+N+ +G G S+ E++ E + V Y R D+ A
Sbjct: 219 EAFARAV----QYDGNESVFNISSGYGTSLNEIIGKIETILGHPVERTYRPGRPFDVPAS 274
Query: 183 WADTSLAKEELGWSTQLTIE 202
D +LAK ELGW ++ ++
Sbjct: 275 VLDNTLAKRELGWEPKVALD 294
>UniRef50_A0B5G2 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Methanomicrobia|Rep: NAD-dependent epimerase/dehydratase
- Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 310
Score = 74.9 bits (176), Expect = 2e-12
Identities = 64/204 (31%), Positives = 100/204 (49%), Gaps = 20/204 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG+ LP E+ ++ Y TK E + +SLRYF
Sbjct: 115 VVFASSSAVYGDSPELPKRESLIPRPMSP-YAVTKLVGEHYCRVFYEIYGI-ECVSLRYF 172
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G G+DP E+ ++P F+ V G +PV V+G DG RD+++V
Sbjct: 173 NVFGP------GQDPASEYAAVIPKFIDAVLSGSQPV--VYG------DGEQTRDFVYVD 218
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ ++ A LS L + N+GTG S+ L++ RV K + Y + R GD+
Sbjct: 219 DVVRANILAC--LSPGAPGLAI-NIGTGYATSLNRLLDAIGRVLKRYIHPIYTEPRPGDV 275
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
AD +LA+E LG++ + +E+
Sbjct: 276 RDSVADITLAREVLGYAPEYGLED 299
>UniRef50_Q97NY4 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=12; Streptococcus pneumoniae|Rep:
NAD-dependent epimerase/dehydratase family protein -
Streptococcus pneumoniae
Length = 233
Score = 74.5 bits (175), Expect = 2e-12
Identities = 46/123 (37%), Positives = 68/123 (55%), Gaps = 4/123 (3%)
Query: 1 MVFSSSCTVYGEP-EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
++FSS+ ++YG P+TE + N Y TK E M+ ++ D W + RY
Sbjct: 114 IMFSSTASLYGNNCIDKPVTEDTLLDPV-NPYAETKLMGERMIYWMANRYD-WKYVIFRY 171
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN GA G K T+++P + + ALG+ L +FG DY+T DG+ IRDYI+V+
Sbjct: 172 FNVAGAEMDASNGLR-VKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVL 230
Query: 120 DLA 122
DLA
Sbjct: 231 DLA 233
>UniRef50_Q2LWN6 Cluster: NAD dependent epimerase/dehydratase
family; n=1; Syntrophus aciditrophicus SB|Rep: NAD
dependent epimerase/dehydratase family - Syntrophus
aciditrophicus (strain SB)
Length = 318
Score = 74.5 bits (175), Expect = 2e-12
Identities = 62/218 (28%), Positives = 104/218 (47%), Gaps = 23/218 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ SS +YG + PI E HPT I+ YG TK +E+ + D ++ +R
Sbjct: 118 VLISSGGVIYGHSLNTPINEEHPTNPISP-YGITKLAVEKYARMFHLTHDL-PVVCVRPG 175
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G IG+ + +A + G + LT++G GT +RDYIHV D
Sbjct: 176 NAYGETQKPFIGQG------FIAAAIASILCGLE--LTLYGES-----GT-VRDYIHVED 221
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKA---KVPLKYVDRRLG 177
+A G VAAL L +YN+G+G+G + +++++ + + +A +V LK + R
Sbjct: 222 IAEGIVAAL-LKGPPG---SIYNIGSGEGRNNRDILDALQPLAQAEGLEVKLKTLPLRKF 277
Query: 178 DISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
D+ D+S + GW+ ++ E+ W W N
Sbjct: 278 DVPVNVLDSSRLSWDTGWTMRIPFEDGIIRTWNWYRDN 315
>UniRef50_A7D7X9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: NAD-dependent
epimerase/dehydratase - Halorubrum lacusprofundi ATCC
49239
Length = 315
Score = 74.5 bits (175), Expect = 2e-12
Identities = 63/203 (31%), Positives = 98/203 (48%), Gaps = 24/203 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG+P +PI ET YG +K + +++ + D + ++LR F
Sbjct: 124 VVFASSAAVYGDPSSVPIGETDAKDP-REPYGVSKLAGDHLVRGYADWKDL-DTVALRLF 181
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +G G P+ FL QV G+ L V G DGT RD++HV D
Sbjct: 182 NVYGPGQTG--GVVPS--------FLEQVQRGEP--LVVHG------DGTQTRDFVHVDD 223
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ VAA ++T + +N+GTG S+ EL V V + + D R D+
Sbjct: 224 VVRAMVAA----ARTDATGESFNVGTGDVTSIHELATVVRDAAPVTVDVVHDDPRPADVP 279
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
ADT+ A+ +L + + T+E+
Sbjct: 280 ESQADTTKARRDLEFEARTTVED 302
>UniRef50_UPI00015BAE89 Cluster: NAD-dependent
epimerase/dehydratase; n=1; Ignicoccus hospitalis
KIN4/I|Rep: NAD-dependent epimerase/dehydratase -
Ignicoccus hospitalis KIN4/I
Length = 293
Score = 72.9 bits (171), Expect = 6e-12
Identities = 61/206 (29%), Positives = 99/206 (48%), Gaps = 31/206 (15%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD--KWNIISLR 58
+VF+S+ VYGE + +P+ E HP + NVYG TK E ++ A W +
Sbjct: 102 VVFASTAAVYGEAKVVPVPEEHPLEPV-NVYGATKVAGEALVNSYRKAFGLRAWTLRLFN 160
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
+ P + G++GE FL + G+ L ++G DG +RD++ V
Sbjct: 161 VYGPSASPSRGVVGE-----------FLRRALKGEP--LRIYG------DGRQVRDFVFV 201
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+ V A L+ + I YN+G+G+GVS+ L +T +K + ++ R GD
Sbjct: 202 DDV----VKAFKLVRE--IPEGTYNVGSGRGVSIITLAKKIIELTGSKSEMVFLPERPGD 255
Query: 179 ISAMWAD-TSLAKEELGWSTQLTIEE 203
+ AD T LA GW ++++EE
Sbjct: 256 VRVSVADVTKLA--AFGWRPRVSLEE 279
>UniRef50_Q5UYL1 Cluster: UDP-glucose 4-epimerase; n=5;
Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 334
Score = 72.9 bits (171), Expect = 6e-12
Identities = 63/218 (28%), Positives = 95/218 (43%), Gaps = 22/218 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V +SS +VYG+P++LP E HPT ++ YG +K E S D + ++LRYF
Sbjct: 132 VMASSSSVYGKPQYLPYDEQHPTTPVSP-YGASKLAAERYACAYSEVYDL-STVALRYFT 189
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G P +N F+++ G+ PV ++G DGT RD+ ++ D+
Sbjct: 190 VYGPRMR------PNMAISN---FVSRCHNGEPPV--IYG------DGTQTRDFTYIEDV 232
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
A + LL + K N+G+ + +K L + L Y +R D
Sbjct: 233 ID---ANMTLLHEDAADGKAVNIGSTDNIEIKTLATEIRDQIDPDLDLVYEERHDADAEH 289
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
A T A+E LG+ TI E F W N D Y
Sbjct: 290 THAATDRAEELLGYDPDHTIREGVAKFIDWYRDNRDWY 327
>UniRef50_Q65E95 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 309
Score = 72.1 bits (169), Expect = 1e-11
Identities = 64/203 (31%), Positives = 95/203 (46%), Gaps = 21/203 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG P++LP+ H T + YG TK +E LK L+ LRY
Sbjct: 113 IVFASSAAVYGNPDYLPVDTRHQTNP-GSPYGLTKLTVENYLK-LAYDLYGTEYCILRYS 170
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +D E + F + GK PV +FG DG RD+I+V D
Sbjct: 171 NVYGPR------QDAKGEGGVVSIFSDLLTSGKAPV--IFG------DGEQSRDFIYVGD 216
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A +V AL +Q+++ L V N G ++V EL ++ T +++ Y D R GDI
Sbjct: 217 VACANVKALK--AQSNVCLNVSN---GFSITVNELFTEMKKATNSELSPIYQDERPGDIR 271
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
K+ L W ++ + E
Sbjct: 272 HSTLCNEETKKILNWEPKMPLAE 294
>UniRef50_A1IA72 Cluster: Putative UDP-glucose-4-epimerase
precursor; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: Putative UDP-glucose-4-epimerase precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 305
Score = 71.7 bits (168), Expect = 1e-11
Identities = 55/212 (25%), Positives = 100/212 (47%), Gaps = 21/212 (9%)
Query: 1 MVF-SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
M+F SS T+YG PE +P+ E+ P ++ +G K IE L A D ++ LR
Sbjct: 110 MIFVSSGGTLYGNPETVPVNESQPLCPLS-YHGAGKIAIEAFLHAF-AHDSGKHVTILRP 167
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G G+ ++ F + L + + + ++G DG+ +RD++++
Sbjct: 168 ANVYGP------GQPLSQGFGFIRTVLEHARMDTE--VKIWG------DGSTVRDFLYIE 213
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ G + +N T YN+G+G+G S+ ++ E+V + ++Y R D+
Sbjct: 214 DMIKGIESVMNADPHTD----TYNIGSGEGHSLNNVIKTVEKVCGRPLKVQYSTARQVDV 269
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ D S E+ GW + ++EE W+W
Sbjct: 270 RKIVLDCSKIMEKTGWKPETSLEEGVRLTWQW 301
>UniRef50_A0K2B4 Cluster: NAD-dependent epimerase/dehydratase; n=10;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Arthrobacter sp. (strain FB24)
Length = 331
Score = 71.3 bits (167), Expect = 2e-11
Identities = 61/216 (28%), Positives = 104/216 (48%), Gaps = 26/216 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +SS +VYG E P +E H + YG K F E M + A + + LRYF
Sbjct: 121 LVAASSASVYGMAEEFPTSERHHHHNNDTFYGAAKSFNEGMARSFRAMTG-LDYVLLRYF 179
Query: 61 NPVGAHPS--GLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N G GL E L+ ++ ++A G+ P+ +FG DG D+IH
Sbjct: 180 NVYGPRMDVHGLYTE-------VLVRWMERIADGQPPL--IFG------DGRQTMDFIHT 224
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY-VDRRLG 177
D+A ++ L + + R VYN+ +G+ S+ +L R +++ +++ DR +
Sbjct: 225 RDVARANI----LAAGSGAREGVYNVASGEETSLLQLAEALLRAMDSELHVEHGPDRAIN 280
Query: 178 DISAMWADTSLAKEELGWSTQLTIEE---MCTDFWR 210
+ ADTS A+ +LG++ + +E+ D+WR
Sbjct: 281 GVVRRLADTSAARLDLGFAAETGLEDGLRELVDWWR 316
>UniRef50_Q8KWC8 Cluster: RB114; n=5; Proteobacteria|Rep: RB114 -
Ruegeria sp. PR1b
Length = 382
Score = 70.9 bits (166), Expect = 3e-11
Identities = 68/221 (30%), Positives = 103/221 (46%), Gaps = 36/221 (16%)
Query: 1 MVF-SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
MV+ SS TVYG P+ ++E HP I++ YG K +E+ L + + LR
Sbjct: 177 MVYLSSGGTVYGVPQQDLVSEDHPLNPISS-YGIVKVAVEKYLF-MEHQLHGLEYVVLRA 234
Query: 60 FNPVGAHPS-----GLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRD 114
NP G GLIG T+L L ++ + V+G DG+ +RD
Sbjct: 235 SNPYGPRQGHRGIQGLIG-------THLW------RLSRQEEIEVWG------DGSIVRD 275
Query: 115 YIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAK----VPLK 170
++HV DLA L LL+ T + ++N G G+G SV E+V A V
Sbjct: 276 FLHVRDLAQ-----LCLLAMTSGKSGIFNAGRGQGASVAEVVEQICATVAASGGRSVAPI 330
Query: 171 YVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
Y R D+ + DT+ A+ ELGW ++T+++ + W W
Sbjct: 331 YKPGRNFDVPRVVLDTTRARAELGWQAEITLQDGIAETWDW 371
>UniRef50_Q1K169 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: NAD-dependent
epimerase/dehydratase - Desulfuromonas acetoxidans DSM
684
Length = 310
Score = 70.9 bits (166), Expect = 3e-11
Identities = 57/215 (26%), Positives = 92/215 (42%), Gaps = 18/215 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VF+SS +YG + LP+ E P +T Y K E + D K + R+FN
Sbjct: 114 VFASSAAIYGNNQQLPLKEDTPPAPLTP-YAVDKLGSEYYI-DFYCRQFKLKTTTFRFFN 171
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G +DP+ ++ ++ L A K+P TVFG DG RD+I V DL
Sbjct: 172 VYGPR------QDPSSPYSGVISILMDRAQNKRP-FTVFG------DGLQSRDFIFVKDL 218
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+Q NLG G ++ EL++ E ++ K+ + + R GDI
Sbjct: 219 VE---ILCKAATQQAPSGNTINLGNGIQTTLLELLSTVESLSNHKLDTSFEEPRPGDIKH 275
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNP 216
AD + ++ ++ + I E W ++ + P
Sbjct: 276 SCADNTRLRQLFSYTPKTNIAEGLKQIWDYEELTP 310
>UniRef50_A4F9Y4 Cluster: UDP-glucose 4-epimerase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: UDP-glucose
4-epimerase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 279
Score = 70.1 bits (164), Expect = 4e-11
Identities = 61/212 (28%), Positives = 99/212 (46%), Gaps = 24/212 (11%)
Query: 2 VFSSSCTVYGEPEHLPITET---HPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLR 58
V +S+ VYG P+ PI E HP Y TK E++L D +A ++R
Sbjct: 84 VLASTGAVYGTPKKQPIGEDAMPHPQSP----YAATKLAAEQLL-DAAAKTGGIAAATVR 138
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
FN G+ +G + T ++P A G P L V+G DG+ +RDY+HV
Sbjct: 139 IFNAAGS-----VGGHADADDTRIIPRALAAAAGHIPHLEVYG------DGSAVRDYVHV 187
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+A+ V L + R +V+N+G SV ++++ E VT +VP+ +
Sbjct: 188 ADIATAIVTVLTRSREG--RHEVFNVG-ATPASVADIIDAAEAVTGRRVPVVRKPANPAE 244
Query: 179 ISAMWADTSLAKEELGWSTQLT-IEEMCTDFW 209
+ ADT+ + LGW + + + ++ D W
Sbjct: 245 SPELRADTTKLR-GLGWEPRRSALRQLIADQW 275
>UniRef50_A1HMB7 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Thermosinus carboxydivorans Nor1|Rep: NAD-dependent
epimerase/dehydratase - Thermosinus carboxydivorans Nor1
Length = 307
Score = 69.3 bits (162), Expect = 8e-11
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 20/211 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +SS VYG+ +P+ E +VYG +K E L + ++ LRY
Sbjct: 111 VVLASSAAVYGDGVAVPVREDAKMAP-ASVYGLSKLTAETYLSMYTRLFGLEGVV-LRYA 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G G GE F +++A G+ LTV+G Y T RD+++ D
Sbjct: 169 NVYGER-QGDGGEGGVVSI-----FTSRMARGE--ALTVYGDGYQT------RDFVYAGD 214
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A+ + AL + + V+N+GT SV +L+ + V V ++Y R GDI
Sbjct: 215 VANANWLAL-ITPDVN---GVFNVGTASETSVNDLIQLLTDVAGRTVDIQYCTPRHGDIY 270
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D LA+E+L W Q+ + E W W
Sbjct: 271 RSALDNRLAREKLCWQPQIPLREGLARTWDW 301
>UniRef50_Q9UXJ4 Cluster: DTDP-glucose 4,6-dehydratase; n=2;
Sulfolobaceae|Rep: DTDP-glucose 4,6-dehydratase -
Sulfolobus solfataricus
Length = 310
Score = 68.9 bits (161), Expect = 1e-10
Identities = 59/207 (28%), Positives = 101/207 (48%), Gaps = 23/207 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETH-----PTGSITNVYGRTKYFIEEMLKDLSAADDKWNIIS 56
+++SS VYG +P ET+ P G I + Y +K F E ++ A + +
Sbjct: 108 IYTSSSEVYGSASIIPTPETYWGYVNPIG-IRSCYDESKRFSEALIM----AYHRQYKLD 162
Query: 57 LRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYI 116
R P + GL ED T + F+ Q G+ +TVFG DG R ++
Sbjct: 163 TRIQRPFNVYGPGL-REDGTYGRV-VSRFIYQALKGED--VTVFG------DGNQTRAFL 212
Query: 117 HVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL 176
++ D A + L+ + + +V+N+G+ K + + EL N+ ++T +K +KY+ R
Sbjct: 213 YISDWVD---ATIKLIYKDGLEGEVFNIGSDKEIKIIELANMIIKLTGSKSRIKYLPPRP 269
Query: 177 GDISAMWADTSLAKEELGWSTQLTIEE 203
D AD + AKE+LGW ++++EE
Sbjct: 270 DDPPRRAADITKAKEKLGWYPKISLEE 296
>UniRef50_Q9WYX9 Cluster: UDP-glucose 4-epimerase, putative; n=5;
Thermotogaceae|Rep: UDP-glucose 4-epimerase, putative -
Thermotoga maritima
Length = 309
Score = 68.1 bits (159), Expect = 2e-10
Identities = 62/204 (30%), Positives = 97/204 (47%), Gaps = 23/204 (11%)
Query: 2 VFSSSC-TVYGEPEHL-PITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+FSS+ +YGE + P ET I+ YG KY E M + A + LRY
Sbjct: 113 IFSSTGGAIYGENVKVFPTPETEIPHPISP-YGIAKYSTE-MYLEFFAREYGLKYTVLRY 170
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP E + F ++ G++ + +FG DG +RDY++V
Sbjct: 171 ANVYGPR------QDPYGEAGVVAIFTERMLRGEE--VHIFG------DGEYVRDYVYVD 216
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D V NLL+ +V+N+GTG+G +V +L + + +T Y R GD+
Sbjct: 217 D-----VVRANLLAMEKGDNEVFNIGTGRGTTVNQLFKLLKEITGYDKEPVYKPPRKGDV 271
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
D + AKE+LGW ++++EE
Sbjct: 272 RKSILDYTKAKEKLGWEPKVSLEE 295
>UniRef50_A5GEM5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Geobacter uraniumreducens Rf4|Rep: NAD-dependent
epimerase/dehydratase - Geobacter uraniumreducens Rf4
Length = 309
Score = 68.1 bits (159), Expect = 2e-10
Identities = 54/211 (25%), Positives = 95/211 (45%), Gaps = 20/211 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V SSS ++GE + LPI E HP + YG TK +E+ + D + LRYF
Sbjct: 112 IVASSSAGIFGELKTLPIKEDHPVEP-DSPYGSTKLCMEKECLSYAKLYDL-EAVCLRYF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G + + N++P A L +P LT+FG DG RD++ V D
Sbjct: 170 NVYGLNQR-------FDAYGNVIPIFAYKMLRGEP-LTIFG------DGEQTRDFLDVRD 215
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ ++ A L + +N+ +G +++ LV + + +++ R GD+
Sbjct: 216 VVQANIKAAMTLGVSG----AFNIASGSRITINRLVELLSAASAINPLVQHGPPRPGDVM 271
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
AD A E ++ ++ +E+ ++ W
Sbjct: 272 HSLADIRAAHEAFDFTPEINLEDGLREYMVW 302
>UniRef50_Q41C61 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Exiguobacterium sibiricum 255-15|Rep:
NAD-dependent epimerase/dehydratase precursor -
Exiguobacterium sibiricum 255-15
Length = 306
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/209 (27%), Positives = 94/209 (44%), Gaps = 28/209 (13%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
F+SS +VYGE + E TG++ + Y KY E + D N+ R+F
Sbjct: 121 FASSSSVYGEQTGA-LLEQQATGNVMSPYAAAKYSAETFCRTYHNLYDM-NVTIFRFFTV 178
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G PSG + L F+ Q AL +P LTVFG +RD+ ++ D+
Sbjct: 179 YG--PSG-------RPDMALFRFIEQ-ALDGQP-LTVFGDP--------VRDFTYIDDIT 219
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
G AL + ++NLG + SV++L + + VP++ R+GD+S
Sbjct: 220 RGMEQALEAKATG-----IFNLGANRPESVRDLAAMLSE--RFNVPVRSAPARIGDVSMT 272
Query: 183 WADTSLAKEELGWSTQLTIEEMCTDFWRW 211
W++T A++ G+ T+ + RW
Sbjct: 273 WSNTDAARQTFGYVPSFTLADGIEQMIRW 301
>UniRef50_Q07KU6 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=2; Alphaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase precursor - Rhodopseudomonas
palustris (strain BisA53)
Length = 317
Score = 66.9 bits (156), Expect = 4e-10
Identities = 62/212 (29%), Positives = 97/212 (45%), Gaps = 23/212 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VF+SS VY P+ P +ET T++YG +K E ++ ++ A + + +R FN
Sbjct: 112 VFASSGAVYA-PDASPHSETEAATVPTDIYGLSKLQGEHYVRYIARARG-FPAVIVRLFN 169
Query: 62 PVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
VG P + +L+P +AQ+ G + + G + RDYIHV D
Sbjct: 170 VVG----------PGETNPHLLPEIIAQLKAGNRSIR--LGNLWPK------RDYIHVRD 211
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG--D 178
A G AA + + NLGT K SV E+V R++ + L R+ D
Sbjct: 212 AARGFAAAALEGAVANGDAVAVNLGTSKAYSVSEVVERLRRISGCQFELLEDSSRVRAVD 271
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWR 210
+ AD + GWS +L+I++ +D WR
Sbjct: 272 RPVLAADVGRIRRMFGWSARLSIDDALSDLWR 303
>UniRef50_Q88XK0 Cluster: UDP-glucose 4-epimerase; n=2;
Lactobacillus plantarum|Rep: UDP-glucose 4-epimerase -
Lactobacillus plantarum
Length = 315
Score = 66.5 bits (155), Expect = 5e-10
Identities = 50/208 (24%), Positives = 99/208 (47%), Gaps = 20/208 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+F+SS VYG LP E ++ Y KY E + D + +R+FN
Sbjct: 117 LFTSSAAVYGNLPELPKKEDSRVDPLSP-YAIDKYATERFVLAYGELYDL-PTVCVRFFN 174
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G G++P+ ++ ++ L KKP T++G DG+ RD+++V D+
Sbjct: 175 VYGP------GQNPSSPYSGVLSILTDCLNNKKP-FTLYG------DGSQTRDFVYVEDV 221
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+ AL L++++ +V+N+ G S+ ++ +E+V + + +K R G++
Sbjct: 222 ----IQALWLITKSDTEHEVFNIANGNEASLNAIIETYEKVAETSLQIKKAPGREGEVKR 277
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFW 209
A+ +LG++T+ ++E + +W
Sbjct: 278 SVANIG-KLIKLGYTTKWSLEAGLSKYW 304
>UniRef50_Q832Q5 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=6; Lactobacillales|Rep: NAD-dependent
epimerase/dehydratase family protein - Enterococcus
faecalis (Streptococcus faecalis)
Length = 324
Score = 66.5 bits (155), Expect = 5e-10
Identities = 56/203 (27%), Positives = 98/203 (48%), Gaps = 16/203 (7%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG+ LP E +T Y K+ E+ + + D ++R+F
Sbjct: 119 LVFASSAAVYGDEPTLPKQEESVIRPLTP-YAVDKFASEKYVLNYCHLYDV-PTSAVRFF 176
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G P+ + + +M ++ ++ +FG DG RD++ V D
Sbjct: 177 NVYG--PNQNPNSPYSGVISIVMDSYKRLLANQEVTFNIFG------DGKQSRDFVFVED 228
Query: 121 LASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
+ V ALNL++ + L +VYN+GTGK + EL++ + K +P++Y + R GDI
Sbjct: 229 V----VQALNLVAHSDQSLGEVYNVGTGKATDLNELISSLNDIMKVTLPVEYKEARAGDI 284
Query: 180 SAMWADTSLAKEELGWSTQLTIE 202
AD S + +G+ + +I+
Sbjct: 285 KDSLADISKLR-AIGYEPKYSIQ 306
>UniRef50_Q7V972 Cluster: Possible UDP-glucose-4-epimerase; n=1;
Prochlorococcus marinus str. MIT 9313|Rep: Possible
UDP-glucose-4-epimerase - Prochlorococcus marinus
(strain MIT 9313)
Length = 308
Score = 66.5 bits (155), Expect = 5e-10
Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 20/196 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS TVYG P+ +PI E HPT I + YG TK IE+ + L N +R NP
Sbjct: 117 SSGGTVYGIPKQVPIAENHPTDPICS-YGITKLAIEKYVS-LYRHLYGLNSTVVRLANPY 174
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G ++P AL +P L ++G DG+ IRD++++ D+
Sbjct: 175 GERQR-------LDSCQGVVPVFLNRALRSEP-LEIWG------DGSTIRDFLYITDV-- 218
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
V AL +S ++N+G+G G+S+ ELV + E + + Y R D+
Sbjct: 219 --VQALLAISHYKGPENLFNVGSGIGLSLCELVKLIENELGRPLQVSYQQSRTFDVPTNV 276
Query: 184 ADTSLAKEELGWSTQL 199
A+ LGWS ++
Sbjct: 277 LSIKRARNCLGWSPKV 292
>UniRef50_Q0YI68 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase; n=3; cellular
organisms|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase - Geobacter sp.
FRC-32
Length = 328
Score = 66.5 bits (155), Expect = 5e-10
Identities = 55/210 (26%), Positives = 90/210 (42%), Gaps = 18/210 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+F+SS +VYG +P E P + + Y TK E + D NI LR+F
Sbjct: 128 LFASSSSVYGNNPKVPFAEADPVDNPISPYAATKKAGELICHTYHHLYDI-NIACLRFFT 186
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P + + + Q KP+ +G DG+ RDY ++ D+
Sbjct: 187 VYGPR------QRPDLAISKFVRLIEQ----GKPI-PFYG------DGSTSRDYTYIGDI 229
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+G AL ++ R ++NLG V++ LV + E K L+ + + GD+
Sbjct: 230 VAGIEKALQWVNTGEKRYDIFNLGGSSPVALNRLVKIIEHQLGKKAVLECLPMQAGDVER 289
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+A+ + LG+ IEE +F RW
Sbjct: 290 TFANIEKSSSVLGYKPVTPIEEGIANFVRW 319
>UniRef50_A1BC39 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Paracoccus denitrificans PD1222|Rep: NAD-dependent
epimerase/dehydratase - Paracoccus denitrificans (strain
Pd 1222)
Length = 316
Score = 66.1 bits (154), Expect = 7e-10
Identities = 59/210 (28%), Positives = 90/210 (42%), Gaps = 17/210 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS VYG+ ET I+ YG K E + + A K + LR+F
Sbjct: 114 VVYASSAAVYGDRSGSTCCETSLPAPISP-YGVDKLGCEHQARAM-AEIHKLRSVGLRFF 171
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +DP + ++ L P TVFG DG RD+I+V D
Sbjct: 172 NVYGPR------QDPASPYAGVISKFCANRLADSPH-TVFG------DGLQSRDFIYVAD 218
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVT-KAKVPLKYVDRRLGDI 179
+ G V A +Q V+NL TG ++ L + + + + P+ + D R GDI
Sbjct: 219 IVEGLVRA-RAYAQGQEGAAVFNLCTGAETTLVGLASEIDGIADRGPTPIIHADPRSGDI 277
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFW 209
D SLA +LG++ + I + W
Sbjct: 278 RMSLGDPSLAARDLGFTARTDIRSGLSRLW 307
>UniRef50_Q8YRD9 Cluster: Nucleotide sugar epimerase; n=6;
Cyanobacteria|Rep: Nucleotide sugar epimerase - Anabaena
sp. (strain PCC 7120)
Length = 316
Score = 65.7 bits (153), Expect = 9e-10
Identities = 53/211 (25%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+S+ +VYG+ E LP E P + + YG TK E L L + ++LRYF
Sbjct: 122 LVFASTSSVYGDAETLPTHEGIPPQPV-SPYGITK-LAAERLCGLYHKNFGVPFVALRYF 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G + P F + Q + V+G DG RD+ V D
Sbjct: 180 TVYGPR------QRPDMAFHKFFKSVLQ-----DEAIPVYG------DGQQTRDFTFVSD 222
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ ++AA ++ + +++N+G G V + E+++ E++ + ++++ +GD
Sbjct: 223 AVAANLAAASVPAAVG---EIFNIGGGSRVVLAEVLDTMEQIVGQPIKRNHIEKAMGDAR 279
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
AD S A++ LG+ ++++ E + W+W
Sbjct: 280 HTAADVSKARKILGYEPKVSLREGLSLEWQW 310
>UniRef50_Q04TJ8 Cluster: Glucose galactose epimerase; n=4;
Leptospira|Rep: Glucose galactose epimerase - Leptospira
borgpetersenii serovar Hardjo-bovis (strain JB197)
Length = 281
Score = 65.7 bits (153), Expect = 9e-10
Identities = 57/191 (29%), Positives = 94/191 (49%), Gaps = 25/191 (13%)
Query: 6 SCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGA 65
S +YG+PE LPI+ETH N Y +K+ E++ + S + NII LR FN G
Sbjct: 98 SAYLYGKPEKLPISETHRIAP-NNPYALSKHLAEQVCEFYSKFKNM-NIIVLRLFNVYGP 155
Query: 66 HPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGH 125
G +F L+P + + KK + + D + RDYI++ D+ +
Sbjct: 156 GQRG--------DF--LIPTILKQVKTKKEIRVL--------DLSPKRDYIYLEDILNSI 197
Query: 126 VAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVP-LKYVDRRLGDISAMWA 184
+AL ++ H +N+G+G SV+E++++ + + +P L R +I + A
Sbjct: 198 SSALFPITGFH----TFNIGSGVSYSVEEVISIAQEIAHTSLPVLSECKERKEEIFDVVA 253
Query: 185 DTSLAKEELGW 195
+ S AKE LGW
Sbjct: 254 NISKAKEVLGW 264
>UniRef50_A0L3Z4 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
- Magnetococcus sp. (strain MC-1)
Length = 310
Score = 65.7 bits (153), Expect = 9e-10
Identities = 52/204 (25%), Positives = 100/204 (49%), Gaps = 20/204 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS YG + LPI E P +T YG K E+ +++ R+F
Sbjct: 114 VVYASSAATYGACQTLPIHEDAPRNPLT-AYGADKLG-SELHAVVASGVHGVPTCGFRFF 171
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP+ ++ ++ F ++ +G+ +T+FG DG RD+++V
Sbjct: 172 NVYGPR------QDPSSPYSGVISIFTNRMRVGQD--VTIFG------DGGQTRDFVYVA 217
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ + +A ++ + KVYN+ TG+ +++ +L + + +K+ + + + R GDI
Sbjct: 218 DVVAHLLAGMDRATG---EAKVYNVCTGREITLLQLALMIRSLLDSKIAIHHGEPRAGDI 274
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
D A ELG ++T+E+
Sbjct: 275 RESLGDPRRATAELGVRAEITLED 298
>UniRef50_Q1AWT4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: NAD-dependent
epimerase/dehydratase - Rubrobacter xylanophilus (strain
DSM 9941 / NBRC 16129)
Length = 317
Score = 65.3 bits (152), Expect = 1e-09
Identities = 62/202 (30%), Positives = 91/202 (45%), Gaps = 24/202 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V +SS +VYG P+ E HP + YG +K EE+++ L A + LRYF
Sbjct: 122 VLASSSSVYGPDGGRPVAEDHPLRP-ASPYGLSKLSAEELVR-LYARERGVRGTVLRYFT 179
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P + F+A G+ PV VFG DG +RD +V D
Sbjct: 180 VYGPR------QRPEMALSR---FIAAAHAGR-PV-EVFG------DGGQVRDMTYVSDA 222
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
VAAL + YN+G G VSV+ ++ VT V Y + GD+ +
Sbjct: 223 VEATVAALERGAGG-----AYNVGGGVRVSVRGMLEAVREVTGRPVEAVYGEAAAGDVRS 277
Query: 182 MWADTSLAKEELGWSTQLTIEE 203
WAD+ A+ ELG+ ++ + E
Sbjct: 278 TWADSRRAERELGYRPRVGLLE 299
>UniRef50_Q0FS47 Cluster: UDP-glucose 4-epimerase; n=1; Roseovarius
sp. HTCC2601|Rep: UDP-glucose 4-epimerase - Roseovarius
sp. HTCC2601
Length = 301
Score = 65.3 bits (152), Expect = 1e-09
Identities = 60/203 (29%), Positives = 95/203 (46%), Gaps = 20/203 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
MV+ SS VYG+ + LPI E P + Y K +E+ L L A + + LR
Sbjct: 108 MVYVSSAGVYGDTDALPIPEDAPLNP-KSFYALQKMAVEQALVML-ANRYGFRLTILRLA 165
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G+ +G P ++ L +A G+ +FGT G +RDY+HV D
Sbjct: 166 NAYGSPLAG-----PGYGVVTIL--LDALATGRP--FKLFGT------GESLRDYVHVSD 210
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ A + + R+ N+GTG+G S+ +LV + ++VT + L+ ++
Sbjct: 211 FCAA--VARSCTADLPERVTTLNIGTGQGTSLADLVTLVQQVTGRALTLERAPLE-SELK 267
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
+ D S A+ LGW+ L IEE
Sbjct: 268 SSVLDISRAQRLLGWTPALGIEE 290
>UniRef50_Q2FN70 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Methanospirillum hungatei JF-1|Rep:
NAD-dependent epimerase/dehydratase precursor -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 313
Score = 65.3 bits (152), Expect = 1e-09
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 28/215 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAA--DDKWNI--IS 56
+V +SS +YG P ET + ++ Y + + L +L AA D + + +
Sbjct: 117 IVLASSAALYGNDYLPPHKETFASVPLS------PYAVGKCLSELYAAVYTDLYGVHSVC 170
Query: 57 LRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYI 116
LR+FN G +DP+ ++ ++ A+ + T+FG DG RD++
Sbjct: 171 LRFFNVYGPK------QDPSSPYSGVISKFMD-AISRDDGFTIFG------DGEQTRDFV 217
Query: 117 HVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL 176
+V+D+ V AL +LS V+N+GTG VS+ L V+ KV ++Y+D R
Sbjct: 218 YVLDV----VQAL-ILSMEKSVSGVFNVGTGASVSINHLARTIMEVSGKKVGIRYLDARD 272
Query: 177 GDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
G++ AD S + +G+ ++ E ++ + W
Sbjct: 273 GEVRHSCADISKISDGMGYKPGYSLIEGLSETYSW 307
>UniRef50_A3HAA1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Caldivirga maquilingensis IC-167|Rep: NAD-dependent
epimerase/dehydratase - Caldivirga maquilingensis IC-167
Length = 301
Score = 65.3 bits (152), Expect = 1e-09
Identities = 59/203 (29%), Positives = 95/203 (46%), Gaps = 22/203 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
MVF SS VYG P LPI E HP I + YG +K EE+++ ++ + LR F
Sbjct: 113 MVFISSAAVYGNPVRLPIPEDHPLRPI-SPYGLSKVLSEEVVRFFGGLGLRF--VILRPF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G G++ +M F+ +V G PV ++G DG RD+IHV+D
Sbjct: 170 NVYGP------GQNSAYAGV-IMRFIERVKRGLPPV--IYG------DGNQARDFIHVLD 214
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A + + + +N+GTG + +L + + + R GDI
Sbjct: 215 VA----RVIERVITGDYWGETFNVGTGVPTRIIDLARLVMGLFGMDGEPLFDKPRPGDIR 270
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
+AD S A+ LG++ +++E+
Sbjct: 271 DSYADISKARSILGFTPSISLED 293
>UniRef50_A6PTX1 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Victivallis vadensis ATCC BAA-548|Rep: NAD-dependent
epimerase/dehydratase - Victivallis vadensis ATCC
BAA-548
Length = 305
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 20/179 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+ FS+S +YG+ +P ET + Y TK E K + K LRYF
Sbjct: 110 LCFSTSAAIYGDNPVVPKVETM-FPEPKSPYAITKLDGEYYCKMFNDTG-KLKTACLRYF 167
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +DP + +P A+ +P LT+FG DG RD+I+V D
Sbjct: 168 NVFGPR------QDPKSAYAAAVPIFTAKAVANEP-LTIFG------DGEQTRDFIYVKD 214
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
+ A N+ TH VYN+ G +++ +L R+T +K ++Y+ R+GD+
Sbjct: 215 -----IVAANVFMATHDFSGVYNVAYGGKITINDLAKEIIRLTGSKSEIQYLPERIGDV 268
>UniRef50_Q9HSU9 Cluster: GDP-D-mannose dehydratase; n=2;
Halobacterium salinarum|Rep: GDP-D-mannose dehydratase -
Halobacterium salinarium (Halobacterium halobium)
Length = 309
Score = 64.9 bits (151), Expect = 2e-09
Identities = 54/204 (26%), Positives = 98/204 (48%), Gaps = 21/204 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +SS +YG E P E+ T + Y +K++ E++ S D + +LRYF
Sbjct: 116 VVVASSAAIYGSTETFPKVESM-TEQPESPYALSKHYTEKLALQASELYDI-DTAALRYF 173
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP ++ ++P F++ + G++PV ++G DG RD+ +
Sbjct: 174 NIYGPR------QDPNGDYAAVIPKFISLMLDGERPV--IYG------DGEQSRDFTFID 219
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
+ ++ A ++ + + +N+G G V+V ELV+V + + Y D R GD+
Sbjct: 220 NAIQANIRA----AEGDVTGEAFNVGCGGRVTVNELVDVLNDLLDTDIDPIYDDPRPGDV 275
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
AD S A+E L + ++ E
Sbjct: 276 RHSHADISKARELLSYEPEVGFSE 299
>UniRef50_A2SRX5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Methanocorpusculum labreanum Z|Rep: NAD-dependent
epimerase/dehydratase - Methanocorpusculum labreanum
(strain ATCC 43576 / DSM 4855 / Z)
Length = 307
Score = 64.9 bits (151), Expect = 2e-09
Identities = 60/206 (29%), Positives = 96/206 (46%), Gaps = 26/206 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLR 58
+V S+S YG+ P E ++ Y +K E ++ + D + + +LR
Sbjct: 112 VVLSASAAAYGDNPVFPKREDMLPEPLSP-YAVSKITAEMYCRNFA---DLFGVETTALR 167
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
YFN G +DP E+ ++P F ++ KKPV +FG DG RD++
Sbjct: 168 YFNVFGPR------QDPNAEYAAVIPKFTERIVHDKKPV--IFG------DGNQTRDFVF 213
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V D+ ++ A+N S T +N+GTG S+ +L + R + Y R G
Sbjct: 214 VKDVVLANMLAMN--SHT---CGTFNIGTGIQTSLNDLAGMIMRAAGISCDIIYEAPRPG 268
Query: 178 DISAMWADTSLAKEELGWSTQLTIEE 203
DI AD S AK ELG++ + +IE+
Sbjct: 269 DIRYSVADISKAKPELGYAPKYSIED 294
>UniRef50_Q83DA9 Cluster: NAD dependent epimerase/dehydratase family
protein; n=9; Bacteria|Rep: NAD dependent
epimerase/dehydratase family protein - Coxiella burnetii
Length = 330
Score = 64.5 bits (150), Expect = 2e-09
Identities = 55/214 (25%), Positives = 100/214 (46%), Gaps = 23/214 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLR 58
+VFSSS +VYG+ P+TE HP S T YG TK E M +A ++ + + LR
Sbjct: 122 LVFSSSASVYGDALEEPMTEAHPFNSRT-FYGATKIAGEAM---ATAYHHRYGLPFVGLR 177
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
Y N G +D + ++ + AL K +T++G DG+ D+++V
Sbjct: 178 YMNVYGPR------QDYRGAYIAVIMKMLD-ALDKGQPMTLYG------DGSQAYDFVYV 224
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D A+ ++ A+ + + YN+GTGK S+ EL +++T ++++ +
Sbjct: 225 EDCAAANICAMKADTVD----EYYNVGTGKRTSILELAKEIQKITGTSDNIQFLPQGTTF 280
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
+ A E++G+ ++ + E W+
Sbjct: 281 VKNRIGCPKKAAEQIGFKAEVGLTEGLQRLIEWR 314
>UniRef50_O67354 Cluster: Nucleotide sugar epimerase; n=4;
Bacteria|Rep: Nucleotide sugar epimerase - Aquifex
aeolicus
Length = 321
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/110 (33%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
DG+ RD+ +V D+A V ALNL ++ N+G K ++KEL+ + E+ T +V
Sbjct: 210 DGSQKRDFTYVDDVAEATVKALNLKGY-----EIINVGNNKPRALKELIELIEKYTGKEV 264
Query: 168 PLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPD 217
++Y D D+ WAD + AK LGW + ++EE W N D
Sbjct: 265 KVEYGDFHKADMRDTWADITKAKRLLGWEPKTSLEEGVKKTVEWFLENWD 314
>UniRef50_Q01U23 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Solibacter usitatus Ellin6076|Rep: NAD-dependent
epimerase/dehydratase - Solibacter usitatus (strain
Ellin6076)
Length = 317
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 18/203 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V+++S + YG+ E LP E T + Y K + E ++ ++LRYF
Sbjct: 115 VVYAASSSAYGDTEVLPKVEDM-TPRPKSPYALQK-LLGEYYCNVFTGVYGLETVALRYF 172
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +DP ++ ++ + AL + T+FG DG RD+ +V D
Sbjct: 173 NVYGPR------QDPGSPYSGVLSLFMKAALNRTAP-TIFG------DGEQSRDFTYVED 219
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A ++ A + KVYN G G +++ + + +++ ++P Y R GD+
Sbjct: 220 VAELNLKAARAKG---VAGKVYNGGNGGRITLNQAWALLQKLEGIEIPSVYGPPRAGDVR 276
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
ADT+LA ELG + + + EE
Sbjct: 277 DSQADTTLAVRELGHAPRYSFEE 299
>UniRef50_Q5L1Q6 Cluster: NDP-sugar epimerase; n=6; Bacillaceae|Rep:
NDP-sugar epimerase - Geobacillus kaustophilus
Length = 318
Score = 63.7 bits (148), Expect = 4e-09
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 23/201 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+++S+ +VYGE P++ET ++ YG TK E + + + + I+ LRYF
Sbjct: 122 IYASTSSVYGERSG-PLSETLEPAPLSP-YGITKLTGEHLCR-VYFREFAVPIVILRYFT 178
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P F F+ Q+ G+ LTVFG DGT RD+ ++ D
Sbjct: 179 VYGPR------QRPDMSFHR---FIRQLLAGQP--LTVFG------DGTQSRDFTYISDC 221
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
G +AAL + + + N+G + SV E++ + E +T + ++Y G+
Sbjct: 222 VDGTIAALE---RDGVIGETINIGGKERASVNEVIRLLETLTGKQAIIQYTPSARGEPKQ 278
Query: 182 MWADTSLAKEELGWSTQLTIE 202
WAD + A+ LG+ +T+E
Sbjct: 279 TWADLAKAERLLGYKPVVTLE 299
>UniRef50_A3PV39 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Mycobacterium sp. JLS|Rep: NAD-dependent
epimerase/dehydratase precursor - Mycobacterium sp.
(strain JLS)
Length = 324
Score = 63.7 bits (148), Expect = 4e-09
Identities = 55/202 (27%), Positives = 89/202 (44%), Gaps = 21/202 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V++SS +VYG+ E P ET T + YG TK E ++ L A + +SLRYF
Sbjct: 124 VYASSSSVYGDAERYPTLETD-TPQPRSPYGVTKLAAEHLM-GLYAQNFGVPTLSLRYFT 181
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P FT F+A+ G+ + +FG+ G IRD+ V D+
Sbjct: 182 VFGPR------QRPDMAFTR---FIARTLAGRP--IEIFGS------GEQIRDFTFVDDV 224
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
S ++AA + VYN+ G V+V E++ E + + + GD+
Sbjct: 225 VSANLAAATAAGV--LPGTVYNISGGASVTVNEILATLEEILDGPILTHRAETVAGDVFR 282
Query: 182 MWADTSLAKEELGWSTQLTIEE 203
A+ +GW +++ E
Sbjct: 283 TGGSNEAARRGIGWEPTVSLHE 304
>UniRef50_A1Y020 Cluster: UDP-glucose 4-epimerase; n=1; Spironucleus
barkhanus|Rep: UDP-glucose 4-epimerase - Spironucleus
barkhanus
Length = 306
Score = 63.7 bits (148), Expect = 4e-09
Identities = 60/221 (27%), Positives = 101/221 (45%), Gaps = 27/221 (12%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEM-LKDLSAADDKWNIISLRYFNP 62
+SS VYG+ ITE + G I+ Y + KY +E + D SA I R+FN
Sbjct: 110 ASSAAVYGDCGTDAITEAYRYGGISP-YAQAKYDMEGIPAGDTSAT----RFIFCRFFNV 164
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G +DP+ +T +M AL P+ T+FG DG RD+++V DL
Sbjct: 165 FGPR------QDPSSPYTGVMSIFIDRALRGIPI-TIFG------DGEQTRDFVYVKDLV 211
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
G A L+ + V+N+GTG+ +V+ L + + +++ + + R GDI
Sbjct: 212 CGAFALLDGGAS-----GVFNIGTGRSTAVQRLAEICADLGGSEI--VHAEPRDGDIKYS 264
Query: 183 WADTSLAKEELGWSTQLTIEEMCTDFWRW-QTMNPDGYPKK 222
+ E +GW + + W+W + + DG+ ++
Sbjct: 265 LSCPEKIFETVGWRAETEFLDGLKATWQWAKDGDSDGFTQR 305
>UniRef50_Q8U032 Cluster: NDP-sugar dehydratase or epimerase; n=5;
Euryarchaeota|Rep: NDP-sugar dehydratase or epimerase -
Pyrococcus furiosus
Length = 307
Score = 63.7 bits (148), Expect = 4e-09
Identities = 58/211 (27%), Positives = 96/211 (45%), Gaps = 21/211 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F+SS VYGE ++LP+ E + I+ YG +K E ++ +I LRYF
Sbjct: 111 IIFASSAAVYGENKNLPLKEDYLPKPISP-YGVSKLAGEHYVRVFYELYGVPGVI-LRYF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G S + ++ + AL +P L +FG DG RD+I+V D
Sbjct: 169 NVYGPRQSSA--------YAGVISIFMKNALKNEP-LVIFG------DGKQTRDFIYVKD 213
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ A L + + K++N+ TGK S+ EL +T + + + R GDI
Sbjct: 214 VVQ---ANLLVAEKERANGKIFNVATGKETSILELALKIIDLTSSSSQILFAPERPGDIK 270
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
AD + + +LG+ ++EE + W
Sbjct: 271 RSVADINEIR-KLGFEPSYSLEEGLKETLEW 300
>UniRef50_A3ERU6 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=2; Bacteria|Rep: Nucleoside-diphosphate-sugar
epimerase - Leptospirillum sp. Group II UBA
Length = 316
Score = 62.9 bits (146), Expect = 7e-09
Identities = 53/211 (25%), Positives = 98/211 (46%), Gaps = 18/211 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V + S +VYG+ +P ET ++ Y +K +E+ + + + ++LRYF
Sbjct: 113 VVIAGSSSVYGDTPGMPRVETLLPSPLSP-YALSK-LSQELFGKIFSKTFGLDTVTLRYF 170
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G +DP E+ ++P + L KK +T+ GT G RD+ + +
Sbjct: 171 NIFGPR------QDPRSEYAAVIPRFVRAIL-KKDAVTINGT------GEQSRDFTFIDN 217
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ ++ A+ T + +N+G G S+ ELV+ + + ++++ R GD
Sbjct: 218 VVQANLLAMET---TRGIGEAFNIGCGSSFSILELVDHLSDILGVRPEVRHLPPRAGDPM 274
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A AD S A++ LG+S ++ E RW
Sbjct: 275 ASQADISKARDLLGYSPKVYFREGLERTARW 305
>UniRef50_Q3E561 Cluster: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:NmrA-like:Nucleotide sugar epimerase; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: NAD-dependent
epimerase/dehydratase:Short-chain
dehydrogenase/reductase SDR:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:NmrA-like:Nucleotide sugar epimerase -
Chloroflexus aurantiacus J-10-fl
Length = 337
Score = 62.5 bits (145), Expect = 9e-09
Identities = 60/213 (28%), Positives = 97/213 (45%), Gaps = 23/213 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V+ SS VYG +P+TE HPT +T VYG K E ++ + +R FN
Sbjct: 117 VYVSSSEVYGTARWVPMTEEHPTYPMT-VYGGGK-LAGECYTRAFWESYRYPTVVVRPFN 174
Query: 62 PVG--AHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
G +H G GE ++P A+ P + +FG DGT RD+ +V
Sbjct: 175 SFGPRSHHEGDSGE--------VIPKFMLRAMAGLP-MVIFG------DGTQTRDFTYVS 219
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVT-KAKVPLKYVDRRLGD 178
D A G + A + + +NLG G+ +S+ EL V + + Y R GD
Sbjct: 220 DTARGIMLAGMVDAAIG---GTFNLGQGREISINELARTVATVVGRPDAAIVYDIPRPGD 276
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ ++AD++ A+ LG++ ++++E W
Sbjct: 277 VLRLYADSTRAQHVLGFTPTVSLQEGLQRLQEW 309
>UniRef50_A4MIF2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Geobacter bemidjiensis Bem|Rep: NAD-dependent
epimerase/dehydratase - Geobacter bemidjiensis Bem
Length = 288
Score = 62.5 bits (145), Expect = 9e-09
Identities = 59/199 (29%), Positives = 91/199 (45%), Gaps = 25/199 (12%)
Query: 6 SCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGA 65
S VYG P LPI E+HP T Y +K+ EE+ + A + + LR FN G
Sbjct: 107 SAYVYGVPHTLPIAESHPVAPNTP-YNHSKWLAEELCR-FYADHFEVPVTVLRPFNIFGP 164
Query: 66 HPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGH 125
GED L+P + + A G D RDY+HV DLA
Sbjct: 165 GQ----GED------FLIPTILKQAKS--------GGTITVKDAAPRRDYLHVDDLAEAL 206
Query: 126 VAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYV-DRRLGDISAMWA 184
+ AL+L R ++N+G+G+ +SV EL+++ R + + + + R+ ++ A
Sbjct: 207 LLALDL----EPRFSLFNVGSGRSISVGELLDMAVRYSPRPLCWQATGEIRVNEVPDTVA 262
Query: 185 DTSLAKEELGWSTQLTIEE 203
D S LGW + T+E+
Sbjct: 263 DISAITRALGWLPRRTLEQ 281
>UniRef50_A0A003 Cluster: MoeE5; n=1; Streptomyces ghanaensis|Rep:
MoeE5 - Streptomyces ghanaensis
Length = 340
Score = 62.5 bits (145), Expect = 9e-09
Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 25/225 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD-KWNIISLRY 59
+V +SS +VYG + + + P + YG TK E + +A D + ++ +LR+
Sbjct: 126 VVVASSSSVYGGADGVMSEDDLPRP--LSPYGVTKLAAERLALAFAARGDAELSVGALRF 183
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
F G G+ P + L+ + L +PV ++G DGT +RD+ HV
Sbjct: 184 FTVYGP------GQRPDMFISRLI----RATLRGEPV-EIYG------DGTQLRDFTHVS 226
Query: 120 DLASGHVAALNLLSQTHIR-LKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+ V AL L + R V N+GTG VSV E+V++ +T + Y R+GD
Sbjct: 227 DV----VRALMLTASVRDRGSAVLNIGTGSAVSVNEVVSMTAELTGLRPCTAYGSARIGD 282
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKKT 223
+ + AD A+ LG++ + + E W + G + T
Sbjct: 283 VRSTTADVRQAQSVLGFTARTGLREGLATQIEWTRRSLSGAEQDT 327
>UniRef50_Q1AYI6 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: NAD-dependent
epimerase/dehydratase - Rubrobacter xylanophilus (strain
DSM 9941 / NBRC 16129)
Length = 315
Score = 62.1 bits (144), Expect = 1e-08
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 18/168 (10%)
Query: 46 SAADDKWNIISLRYFNPVGAHP---SGLIGEDPTKEFTNLMPFLAQVALGKK-PVLTVFG 101
++AD ++ SL V A P SG G+ P L+ ++ GK+ PV+ +
Sbjct: 142 ASADLLGHVYSLEGLRVVRARPFNHSGP-GQSPAFVLPTLVEQFVEIEAGKREPVIRLGN 200
Query: 102 TDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFER 161
D +RD+ V D+ G+ AL L ++ + YNLG+G+G SV+EL +
Sbjct: 201 LD-------SVRDFSDVRDIVRGYRLAL-LKGRSG---EPYNLGSGRGTSVRELFEMVRE 249
Query: 162 VTKAKVPLKYVDRR--LGDISAMWADTSLAKEELGWSTQLTIEEMCTD 207
+ +V L+ R + DI + ADTS A+EELGW ++++E+ D
Sbjct: 250 KAEQEVELQVEPSRTRIIDIPYLVADTSKAREELGWEPEVSLEQTLHD 297
>UniRef50_Q5KWG9 Cluster: Nucleotide sugar epimerase; n=1;
Geobacillus kaustophilus|Rep: Nucleotide sugar epimerase
- Geobacillus kaustophilus
Length = 314
Score = 61.7 bits (143), Expect = 2e-08
Identities = 54/205 (26%), Positives = 96/205 (46%), Gaps = 27/205 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F+SS +VYG+ ++P+ E G + + Y KY E + + + RYF
Sbjct: 121 VLFASSSSVYGDRGNVPLREEMADGRVVSPYAAAKYGAESFCHAYAHLYG-YQMTIFRYF 179
Query: 61 NPVG--AHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
G P IG FL ++ G++ + V+G GT RDY ++
Sbjct: 180 TVYGPWGRPDMAIG-----------TFLRRLLAGEE--IVVYG------KGTA-RDYTYI 219
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+ G +AAL+ ++ R +V+NLG G V++++L+ R + + + R GD
Sbjct: 220 DDIVEGMIAALH---RSGGRSEVFNLGAGAPVTMEQLLAEL-RKHFPDLKIVHAPERKGD 275
Query: 179 ISAMWADTSLAKEELGWSTQLTIEE 203
+ A WAD + A+ G+ ++ E
Sbjct: 276 VKATWADITKAERAFGYKPKVAFAE 300
>UniRef50_Q4E8F1 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=3; Wolbachia|Rep: NAD-dependent
epimerase/dehydratase family protein - Wolbachia
endosymbiont of Drosophila simulans
Length = 319
Score = 61.7 bits (143), Expect = 2e-08
Identities = 55/219 (25%), Positives = 99/219 (45%), Gaps = 20/219 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+++SS VYGE + LP+ E+ I N Y + K FIEE + +L ++ +N+ LR+ N
Sbjct: 100 IYASSREVYGEQKELPVAESASINPINN-YAKGKAFIEEQVINLKGSN--FNVAILRFSN 156
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G GL+ + ++P L AL P+ + G + + D+ ++ D+
Sbjct: 157 VYG----GLLDHS-----SRVIPALCINALKGDPI-RIEGKEC-------VFDFTYLDDV 199
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
G + L L +L T +++ L +VT++ + + R D++
Sbjct: 200 IEGIYLTVKYLQNEKSSLPAIHLTTNSPCTLENLAKTILKVTESDSRIDFYPPRNFDVTK 259
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYP 220
D + AKE LGWS + +++ F + N YP
Sbjct: 260 FHGDFTRAKELLGWSPKHSLKVGLGKFIKSLQNNTQEYP 298
>UniRef50_Q11WU7 Cluster: UDP-galactose-4-epimerase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: UDP-galactose-4-epimerase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 319
Score = 61.7 bits (143), Expect = 2e-08
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 18/216 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS +VYG+ P E G++ + Y +K IE K S + I++RYF
Sbjct: 118 VVYASSSSVYGDDPGSPKEEDR-LGNVLSPYAASKRSIELYAKAFSNVYP-FRFIAMRYF 175
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G ++ + ++P F+ + G++ T+FG DG+ RD+ +
Sbjct: 176 NVFGPR------QNAQGAYAAVIPQFITALLNGQQA--TIFG------DGSQTRDFTFID 221
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
++ ++ AL+ + + YN+ G S+ + + + + Y D R GDI
Sbjct: 222 NVLQMNIKALSTDNADAFN-RYYNVACGSTTSLNRVYAILAGCAGSDIKPHYTDPRQGDI 280
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
A+ SLA++ +G+ ++ IEE + W N
Sbjct: 281 KDSLANISLAQKHIGYKPEIQIEEGLIKTFDWFKKN 316
>UniRef50_A0LGE9 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: NAD-dependent
epimerase/dehydratase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 315
Score = 61.7 bits (143), Expect = 2e-08
Identities = 54/209 (25%), Positives = 94/209 (44%), Gaps = 20/209 (9%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
FSS VYG PE LP+ E I+ YG K +E+ L S II +R NP
Sbjct: 117 FSSGGAVYGNPESLPVFEEARAKPISP-YGVAKLMMEKYLYMFSYLYGLEYII-VRPSNP 174
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G + +GE ++P + L + + +++G DG G +DY++V DLA
Sbjct: 175 FGPRQN-YMGEQ------GVIPIFFRKILDDETI-SIWG------DGKGTKDYLYVEDLA 220
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
V+ L ++ +YN+ +G G S+ +++ + + +++V +R D+S +
Sbjct: 221 GAVVS----LIESGFDKSIYNISSGIGRSLLSIIDNISNICGKRPNIEFVAKRTHDVSNI 276
Query: 183 WADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ GW T E+ ++W
Sbjct: 277 TLSFDKIRNRTGWVPTTTFEDGLIQTFKW 305
>UniRef50_Q58455 Cluster: Uncharacterized protein MJ1055; n=4;
cellular organisms|Rep: Uncharacterized protein MJ1055 -
Methanococcus jannaschii
Length = 326
Score = 61.3 bits (142), Expect = 2e-08
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 22/217 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS +VYG +P +E ++Y TK E++ + +I LR+F
Sbjct: 127 VVYASSSSVYGGNRKIPFSEDDRVDKPISLYASTKRS-NELMAHVYHHLYGIKMIGLRFF 185
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G + G F F + LGK+ + YN G RD+ ++ D
Sbjct: 186 TVYGEY-----GRPDMAYFK----FAKNILLGKEIEV------YNY--GNMERDFTYISD 228
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ G + A+ + +++NLG K V + + + E+ K K++ + GD+
Sbjct: 229 VVDGILRAI----KKDFDYEIFNLGNSKPVKLMYFIELIEKYLNKKAKKKFLPMQDGDVL 284
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPD 217
+AD S +++ LG+ ++TIEE F W N D
Sbjct: 285 RTYADLSKSEKLLGYKPKVTIEEGLKRFCNWFLENKD 321
>UniRef50_Q1IM02 Cluster: NAD-dependent epimerase/dehydratase; n=6;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Acidobacteria bacterium (strain Ellin345)
Length = 322
Score = 60.9 bits (141), Expect = 3e-08
Identities = 48/196 (24%), Positives = 93/196 (47%), Gaps = 18/196 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++++ S + YG+ LP E I+ Y +K E L+ + A +++RYF
Sbjct: 113 VIYAGSSSAYGDTPTLPKNEEMLANPISP-YAVSKLTGEYYLRSMYAVHGM-ETVTIRYF 170
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G + +DP +++ ++ F+ Q+ G+ P T+ G DG RD+ ++
Sbjct: 171 NVFGPY------QDPGSQYSGVLAKFIPQMLRGETP--TIHG------DGEQSRDFTYIE 216
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
++ ++A N ++ + +V+N+ TG +S+ E V + +T + + R GD+
Sbjct: 217 NVVKANIALANAPAE-RVAGEVFNVATGTRISLNETVALLREMTGYTGAVHHGPERKGDV 275
Query: 180 SAMWADTSLAKEELGW 195
AD S AK G+
Sbjct: 276 KHSLADISKAKRAFGF 291
>UniRef50_A7HFB5 Cluster: NAD-dependent epimerase/dehydratase; n=2;
cellular organisms|Rep: NAD-dependent
epimerase/dehydratase - Anaeromyxobacter sp. Fw109-5
Length = 373
Score = 60.5 bits (140), Expect = 4e-08
Identities = 55/204 (26%), Positives = 93/204 (45%), Gaps = 21/204 (10%)
Query: 11 GEP-EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSG 69
GEP +P ET ++ +VY TKY E + + A +LR+FN G +
Sbjct: 164 GEPLSPVPTPETKAP-ALPSVYALTKYDQERLCLTVGRAYGI-PTTALRFFNVYGTRQA- 220
Query: 70 LIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAAL 129
+ +T ++ A L ++P L DG RD++HV D+A + AL
Sbjct: 221 -----LSNPYTGVLAIFAARLLNRRPPLV-------NEDGLQRRDFVHVQDVARACLLAL 268
Query: 130 NLLSQTHIRLKVYNLGTGKGVSVKELVN-VFERVTKAKVPLKYVDR-RLGDISAMWADTS 187
+ L N+G+G+ +V+E+ + + + ++ + R R GDI +AD S
Sbjct: 269 EAPEAAGLAL---NVGSGRSFTVREIAERLATALGEERIVPEITGRYRAGDIRHCFADVS 325
Query: 188 LAKEELGWSTQLTIEEMCTDFWRW 211
LA+ LG+ Q+ +E T+ W
Sbjct: 326 LARRVLGYEPQVAFDEGLTELCGW 349
>UniRef50_A0GDZ4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Burkholderia phytofirmans PsJN|Rep: NAD-dependent
epimerase/dehydratase - Burkholderia phytofirmans PsJN
Length = 314
Score = 60.5 bits (140), Expect = 4e-08
Identities = 50/197 (25%), Positives = 86/197 (43%), Gaps = 17/197 (8%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS VYG P +PI E H + YG K E L D+ + + +R NP
Sbjct: 112 SSGGAVYGTPTRIPIDEDHSRSPL-GAYGAAKLAAETYL-DVYRRQWQVDARIMRLSNPY 169
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G G++ F A+ K+ + ++G +G +RDY+++ D
Sbjct: 170 GP------GQNINGNQGAATIFAARAV--KQQTIDIWG------EGDIVRDYLYIDDAID 215
Query: 124 GHVAALNLLSQTHIR-LKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
+N + + V N+G+GKG+S+ E++ ER+ K K+ ++Y R D+
Sbjct: 216 AFSRFMNTDAAVFENAMPVLNVGSGKGISLNEIILTIERILKRKIKVQYSPSRGFDVDVN 275
Query: 183 WADTSLAKEELGWSTQL 199
D + A +GW ++
Sbjct: 276 VLDVTHAYHLIGWRPKI 292
>UniRef50_A0FYZ6 Cluster: NAD-dependent epimerase/dehydratase; n=4;
Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
- Burkholderia phymatum STM815
Length = 379
Score = 60.5 bits (140), Expect = 4e-08
Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 21/223 (9%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
F C GE T+ + ++VYG TKY E+M+ + + +LRY N
Sbjct: 161 FDFMCPRTGEKMECLPTDEDSRINPSSVYGITKYNQEQMVMTVCRSLGIAGC-ALRYQNV 219
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G G+ + +T ++ + + P+ VF DG RD++++ D+
Sbjct: 220 YGP------GQSLSNPYTGILSIFSTRIKNENPI-NVF------EDGKESRDFVYIDDVC 266
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDR-RLGDISA 181
+AAL LS T +++ +G+G+ V + + ++VP+ RLGDI
Sbjct: 267 DATMAAL--LSPTADN-EIFGIGSGERTEVLGVATKLRDLYGSRVPINVTGAFRLGDIRH 323
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW---QTMNPDGYPK 221
+AD + A+E LG+ +++ +E F W Q + PD Y K
Sbjct: 324 NYADLTRARERLGFQPKVSFDEGIARFAAWVERQDVAPDTYDK 366
>UniRef50_UPI0000384B58 Cluster: COG0451:
Nucleoside-diphosphate-sugar epimerases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0451:
Nucleoside-diphosphate-sugar epimerases -
Magnetospirillum magnetotacticum MS-1
Length = 299
Score = 60.1 bits (139), Expect = 5e-08
Identities = 65/203 (32%), Positives = 92/203 (45%), Gaps = 34/203 (16%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ +SS VYG P E HP + N YG TK+ EE S + S R F
Sbjct: 118 VINASSAAVYGIAA-APTAEDHPINPV-NPYGLTKWMAEEACAHWSKVFGVATL-SFRIF 174
Query: 61 NPVG--AHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N G A SG IG FL + A G+ LTV G DGT RD+IHV
Sbjct: 175 NCYGPRATASGPIGF-----------FLKKAAAGE--ALTVTG------DGTQERDFIHV 215
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+ + +A + + YNLG+G+ +V L E V A + Y+ R G+
Sbjct: 216 SDVVAAFLAG----AASEKSSAAYNLGSGRPETVNRLA---ELVGGA---ITYIPARPGE 265
Query: 179 ISAMWADTSLAKEELGWSTQLTI 201
+ ADT+ + ELGW ++++
Sbjct: 266 PKVILADTTRIRAELGWEPKVSL 288
>UniRef50_Q67KU6 Cluster: UDP-glucose 4-epimerase; n=1;
Symbiobacterium thermophilum|Rep: UDP-glucose
4-epimerase - Symbiobacterium thermophilum
Length = 321
Score = 60.1 bits (139), Expect = 5e-08
Identities = 59/204 (28%), Positives = 90/204 (44%), Gaps = 19/204 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VFSSS VYG P LP+TE P + + YG K E ++ ++ +RY N
Sbjct: 117 VFSSSAAVYGIPSSLPVTEDAPFSPL-SPYGIAKVAAEGYIRAYCFLHGLKAVV-MRYSN 174
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G G+ + F+ + G PV FG DG RD+I+V D+
Sbjct: 175 VFGPRQKA-AGDGGV-----VANFVEAILRGHPPVF--FG------DGGQTRDFIYVKDV 220
Query: 122 ASGHVAALNLLSQTHI-RLKVYNLGTGKGVSVKELVNVF-ERVTKAKVPLKYVDRRLGDI 179
A + A++ L ++ V N+ +G S++ L + E V +A P+ R GDI
Sbjct: 221 ADATLKAIDYLDKSGTSEYLVVNISSGVETSLRTLYTLLCELVKQAPEPI-LTPPREGDI 279
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
D A+E LGW ++E+
Sbjct: 280 RHSCLDNRKAREYLGWLPGYSLEQ 303
>UniRef50_A6BZU3 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 324
Score = 60.1 bits (139), Expect = 5e-08
Identities = 54/224 (24%), Positives = 97/224 (43%), Gaps = 20/224 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++ S + YG E +P E T + + Y K E + + + D + +RYF
Sbjct: 114 VVYAGSSSAYGNQEQMPKHEGQ-TPEVLSPYAAAKLAGELYCQAFANSYDL-ETVRIRYF 171
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVAL-GKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP ++ ++P L G++P+ +FG DG RD+ V
Sbjct: 172 NVFGPR------QDPNSPYSAVIPLFTSALLEGRRPM--IFG------DGLQSRDFTFVD 217
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVN-VFERVTKAKVPLKYVDRRLGD 178
++ ++ A + + VYN G +++ +L+ + ++ K P + R GD
Sbjct: 218 NVVQANILASQAPADK-VSGNVYNAACGSSLNLIDLLKFICNQLDKPYDP-DFQPARTGD 275
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKK 222
+ WAD S A+ +LG+ + IEE W + KK
Sbjct: 276 VKHSWADISAAQRDLGYEPVVEIEEGLRKTIDWYAGSTSSESKK 319
>UniRef50_Q868I5 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=2;
Giardia intestinalis|Rep: UDP-N-acetylglucosamine
4-epimerase - Giardia lamblia (Giardia intestinalis)
Length = 385
Score = 60.1 bits (139), Expect = 5e-08
Identities = 60/235 (25%), Positives = 100/235 (42%), Gaps = 45/235 (19%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
+S+ YG+ ITE P G I+ Y +K +E + + + I R+FN
Sbjct: 126 ASTAAYYGDCGKSAITEAFPYGGISP-YAESKMEMERLGAEFQKTS-RCRFIFCRFFNVY 183
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G +DP+ +T +M +KP+ T+FGT T RD++ + DL
Sbjct: 184 GPR------QDPSSPYTGVMSIFMDRCAARKPI-TIFGTGEQT------RDFVFIKDLI- 229
Query: 124 GHVAALNLLSQ----------------THIRLKVY----------NLGTGKGVSVKELVN 157
VAA+NLL Q ++ Y N+G+G +SV EL
Sbjct: 230 --VAAINLLGQLDKFPIGADAVQQNDPEEVQRSAYTGEGVYPTVFNIGSGISISVNELAE 287
Query: 158 VFERVT-KAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ + V+ + +V + + + R GDI +D + + GWS T+ ++ W W
Sbjct: 288 LAKIVSGRHEVEIVHGEPRSGDILHSLSDCTRIRNATGWSASTTLRVGMSETWGW 342
>UniRef50_A0UVI4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Clostridium cellulolyticum H10|Rep: NAD-dependent
epimerase/dehydratase - Clostridium cellulolyticum H10
Length = 309
Score = 59.3 bits (137), Expect = 8e-08
Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 22/215 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS YG P +PITE I + YG +K E K + A + + LRY
Sbjct: 111 IVFASSMAAYGWPRQIPITEDCDLAPI-SPYGFSKARCELYCK-IFAKRFGISYVILRYC 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G + + ++ AL +P+ TV G DG I+D+++V D
Sbjct: 169 NIYGI-------KQTLSPYVGVLTTFINQALSSQPI-TVNG------DGEQIKDFVNVED 214
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A NLL+ + + ++N+G+G SV +L ++ K + Y+ G++
Sbjct: 215 IAHA-----NLLAMEYEKNDIFNIGSGIKTSVNQLADMVLSNFKDGKKI-YMPLPEGEVD 268
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
++ AD S A+ LG+ + +E++ W N
Sbjct: 269 SICADISKAQNLLGYKAEGDLEKLLPQIIEWWKNN 303
>UniRef50_Q58M85 Cluster: Nucleotide-sugar epimerase; n=1;
Cyanophage P-SSM2|Rep: Nucleotide-sugar epimerase -
Cyanophage P-SSM2
Length = 301
Score = 59.3 bits (137), Expect = 8e-08
Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 25/201 (12%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V+SS+ + YG P ET P + N Y TK E++ K + ++ LRYFN
Sbjct: 115 VYSSTSSGYGN-NPFPNVETQPDDCL-NPYSATKVAGEKLCKMYTNLYGLETVV-LRYFN 171
Query: 62 PVGAHPSGLIGEDPTK-EFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G PTK ++ ++ + K+P LT+ G DG+ RD++HV D
Sbjct: 172 VFGQR-------SPTKGQYAPVIGIFRRQLDSKEP-LTIVG------DGSQRRDFVHVND 217
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A + A L Q H +V+N+G+GK SV+E+ +V ++ +V Y+ +R G++
Sbjct: 218 VARANYLASILPLQGH-EGEVFNVGSGKNYSVQEIADV---ISDNQV---YLPKREGEMD 270
Query: 181 AMWADTSLAKEELGWSTQLTI 201
A+ +GW ++ +
Sbjct: 271 TTLANIDKIGSIIGWKPEVDV 291
>UniRef50_Q1VKN8 Cluster: UDP-glucose 4-epimerase; n=1;
Psychroflexus torquis ATCC 700755|Rep: UDP-glucose
4-epimerase - Psychroflexus torquis ATCC 700755
Length = 70
Score = 58.8 bits (136), Expect = 1e-07
Identities = 24/64 (37%), Positives = 38/64 (59%)
Query: 146 TGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMC 205
TG+ SV ELV++F + + +VDRR GD++ +++ + A EL W +L +E MC
Sbjct: 2 TGQSTSVVELVSIFNKTNGFNIITNFVDRRKGDVAICYSNPNKAHNELNWIAKLNLERMC 61
Query: 206 TDFW 209
D W
Sbjct: 62 KDAW 65
>UniRef50_Q8U170 Cluster: UDP-or dTTP-glucose 4-epimerase or
4-6-dehydratase; n=5; Euryarchaeota|Rep: UDP-or
dTTP-glucose 4-epimerase or 4-6-dehydratase - Pyrococcus
furiosus
Length = 336
Score = 58.8 bits (136), Expect = 1e-07
Identities = 56/215 (26%), Positives = 99/215 (46%), Gaps = 23/215 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETH-----PTGSITNVYGRTKYFIEEMLKDLSAADDKWNIIS 56
+F+S+ +YG PE +P ET+ P G I + Y +K + E L ++
Sbjct: 135 IFASTSEIYGHPEVVPTPETYWGYVNPIG-IRSCYDESKR-LGEALTMAYYRQFNVDVRI 192
Query: 57 LRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYI 116
+R FN G + D + ++P AL ++P+ TVFG DG+ R +
Sbjct: 193 VRIFNTYGPR----MRADGV--YGRVVPRFISQALNEEPI-TVFG------DGSQTRSFC 239
Query: 117 HVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL 176
+V DL +G L + + R +V NLG + +S+ EL + +++T + P+++
Sbjct: 240 YVTDLITG---VLKFAAVENGRGEVVNLGNPREISILELAYLIKKLTNSDSPIEFHPLPP 296
Query: 177 GDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D D S A++ L W ++ +EE +W
Sbjct: 297 DDPPRRCPDISKAQKLLNWKPKVELEEGLKKTIKW 331
>UniRef50_Q316B8 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=1; Desulfovibrio desulfuricans G20|Rep:
NAD-dependent epimerase/dehydratase family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 58.4 bits (135), Expect = 1e-07
Identities = 62/210 (29%), Positives = 96/210 (45%), Gaps = 27/210 (12%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
F SS VYG PE LP++E P ++ YG K E+++ + ++ LR F+
Sbjct: 111 FPSSAAVYGNPERLPVSEDAPLCPVSP-YGCHKVLSEKLISQYHSLYGIEYVV-LRVFS- 167
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
GE +K+ L + G+ + + GT T RD+IHV DLA
Sbjct: 168 -------CYGEGLSKQL--LWDAAVKACAGR---VELSGTGEET------RDFIHVHDLA 209
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVD-RRLGDISA 181
+A L +L + N +G+ VSVKEL + R +A VP+ + +R GD
Sbjct: 210 --RLAELLMLRD--VSCVTLNAASGRQVSVKELAGLLMRGLEADVPVLFSGAQRQGDPLR 265
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
AD + + LG+ +++EE F RW
Sbjct: 266 WQADVA-RMQSLGFEPHISLEEGVRRFARW 294
>UniRef50_A1FN39 Cluster: NAD-dependent epimerase/dehydratase; n=23;
cellular organisms|Rep: NAD-dependent
epimerase/dehydratase - Pseudomonas putida W619
Length = 355
Score = 58.4 bits (135), Expect = 1e-07
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 19/186 (10%)
Query: 1 MVFSSSCTVYGEP-EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+VF+SS VYG E I E P +T Y K E+ L D + R+
Sbjct: 161 VVFASSAAVYGNNGEGQSIAEDTPKAPLTP-YAVDKLASEQYL-DFYRRQHGLEPVVFRF 218
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN G +DP+ ++ ++ ++ A P+ TVFG DG RD+++V
Sbjct: 219 FNIFGPR------QDPSSPYSGVISIFSERATQGLPI-TVFG------DGEQTRDFLYVG 265
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
DL V AL Q + N+G + S+ +L+ E V + P+ Y + R GDI
Sbjct: 266 DLVQVMVQALE---QPQVEEGAVNIGLNQATSLNQLLKALETVVGSLPPVSYGEARSGDI 322
Query: 180 SAMWAD 185
AD
Sbjct: 323 RHSRAD 328
>UniRef50_Q04973 Cluster: Vi polysaccharide biosynthesis protein
vipB/tviC; n=54; Bacteria|Rep: Vi polysaccharide
biosynthesis protein vipB/tviC - Salmonella typhi
Length = 348
Score = 58.0 bits (134), Expect = 2e-07
Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 24/216 (11%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
+++S + YG+ LP E G + Y TKY + E+ D+ A ++N I LRYFN
Sbjct: 138 YAASSSTYGDHPDLPKIEER-IGRPLSPYAVTKY-VNELYADVFARSYEFNAIGLRYFNV 195
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G ++P ++ ++P L +P+ Y DG+ RD+ ++ ++
Sbjct: 196 FGRR------QNPNGAYSAVIPRWILSLLKDEPI-------YINGDGSTSRDFCYIENVI 242
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKEL-------VNVFERVTKAKVPLKYVDRR 175
++ + + + KVYN+ G S+ EL +N++ P+ Y D R
Sbjct: 243 QANLLSATT-NDLASKNKVYNVAVGDRTSLNELYYLIRDGLNLWRNEQSRAEPI-YKDFR 300
Query: 176 LGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
GD+ AD + K L + + I+E +W
Sbjct: 301 DGDVKHSQADITKIKTFLSYEPEFDIKEGLKQTLKW 336
>UniRef50_Q982P5 Cluster: UDP-glucose 4-epimerase; n=1;
Mesorhizobium loti|Rep: UDP-glucose 4-epimerase -
Rhizobium loti (Mesorhizobium loti)
Length = 310
Score = 57.6 bits (133), Expect = 2e-07
Identities = 56/211 (26%), Positives = 91/211 (43%), Gaps = 21/211 (9%)
Query: 3 FSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
FSS TVYGE + +PI E PT + YG +K IE ++ L N +R NP
Sbjct: 113 FSSGGTVYGEVDEIPIREDSPTNPV-GAYGVSKLMIEHYVR-LYERKYGLNSFIVRLANP 170
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G P + + L+ F + + V TV+G DG+ RDY++V D+A
Sbjct: 171 FG--PWQVEAHNQ-----GLVAFAGHLIQSDRQV-TVYG------DGSARRDYVYVEDVA 216
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTG-KGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+ +N + +N+G G G S+ ++++ E + +K R D+ +
Sbjct: 217 NFVARLINYNGAK----RTFNVGGGGNGQSILDVIHAIETSLGKRAMIKREPSRPFDVPS 272
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQ 212
A++ELGW + + WQ
Sbjct: 273 NVLSIERAEKELGWRPATSFPDGIDYTLSWQ 303
>UniRef50_Q2S4X1 Cluster: UDP-glucuronate 5'-epimerase; n=3;
Bacteria|Rep: UDP-glucuronate 5'-epimerase -
Salinibacter ruber (strain DSM 13855)
Length = 327
Score = 57.6 bits (133), Expect = 2e-07
Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 19/211 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+F SS +VYG E +P +E P + Y TK E + D + LR+F
Sbjct: 122 LFGSSSSVYGNNEKVPFSEEDPVRHPISPYAATKRSGELLAHTFHHLYDM-TVHCLRFFT 180
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G P + + A+ L +P+ T++G DGT RDY +V D+
Sbjct: 181 VYG----------PRQRPDLAIHKFARQLLTDQPI-TMYG------DGTSSRDYTYVDDI 223
Query: 122 ASGHVAALNLLSQTHI-RLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
G + +L+ ++ NLG + +K+L++ +K + + GD+
Sbjct: 224 VDGVMRSLHRAKSLEAPEYEIINLGGSETTQLKDLISGIADAMGITPEIKQLPEQPGDVE 283
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+AD S A+E LG+ I+ F W
Sbjct: 284 RTYADISKAEELLGYEPDTPIQVGLQKFVSW 314
>UniRef50_A4A6D1 Cluster: UDP-glucose 4-epimerase; n=1;
Congregibacter litoralis KT71|Rep: UDP-glucose
4-epimerase - Congregibacter litoralis KT71
Length = 312
Score = 57.6 bits (133), Expect = 2e-07
Identities = 54/211 (25%), Positives = 96/211 (45%), Gaps = 20/211 (9%)
Query: 4 SSSCTVYGEPEHLPITETHPT--GSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
SS VYG+PE LP T + + + YG +K E +L S+ + LR N
Sbjct: 112 SSGGAVYGQPEQLPHTAISESLLPAPLSYYGASKVAAESLLHAFSSRTGT-PVTVLRPSN 170
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G G+ P K F ++P L L + V + G +++ RDY++V D
Sbjct: 171 IYGP------GQLPKKGFA-VIPTLL-TTLRENRVFEIVGNMHSS------RDYLYVDDF 216
Query: 122 ASGHVAALNLLSQTHIR-LKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
H+ ++ + +R + YN+ +G ++ EL+ E+V+ K L+ +D R D +
Sbjct: 217 C--HLLSMCIQKSGTMRGHETYNVCSGHSTTLAELIGHSEKVSGNKAKLRQIDARKEDPN 274
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ + A + WS++ ++ E W+W
Sbjct: 275 IVELSGAKADDHFSWSSETSLTEGLESTWQW 305
>UniRef50_Q9K7I2 Cluster: UDP-glucose 4-epimerase; n=17; cellular
organisms|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 308
Score = 57.2 bits (132), Expect = 3e-07
Identities = 55/203 (27%), Positives = 90/203 (44%), Gaps = 23/203 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDL-SAADDKWNIISLRY 59
++++SSC VYG+ ITE P I + YG +K E ++ K+ I RY
Sbjct: 114 VIYASSCAVYGDTGDSSITEDFPIQPI-SFYGISKSVPEMYIRQFHDLYGLKYTI--FRY 170
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G + GE + F + ++P+ ++G +G RD+I+V
Sbjct: 171 ANVYGPRQTSK-GEGGV-----ISIFTTKALKREQPI--IYG------NGEQTRDFIYVE 216
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+A + AL++ +++N+GT + S+ EL N V KY R GDI
Sbjct: 217 DIAKANALALDIGDN-----EIFNIGTNQKTSINELYNKVNVVRPFAPSAKYTSPREGDI 271
Query: 180 SAMWADTSLAKEELGWSTQLTIE 202
AK+ LGW +++E
Sbjct: 272 LHSRLSYVKAKKILGWKPSVSLE 294
>UniRef50_Q9K6S7 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus
halodurans|Rep: UDP-glucose 4-epimerase - Bacillus
halodurans
Length = 311
Score = 57.2 bits (132), Expect = 3e-07
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 17/202 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VF+SS +YG LPI E P + + YG +KY E +K N+ LR+ N
Sbjct: 114 VFASSAAIYGPSHTLPIREEFPALPL-SPYGTSKYAAEAYVKTYGRLYG-LNVHVLRFAN 171
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + E + F+ ++ ++P+ +FG DG RD+I V+D+
Sbjct: 172 VYGPR------QTAETEAGVISIFIEKLLKNEQPI--IFG------DGKQTRDFIFVLDV 217
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
+ + L + + VYN+ TG SV++L+ + R GDI
Sbjct: 218 VNAIRSCLETETNQEVD-PVYNVSTGLQTSVEDLLKELCAQLNVTYAPAFEQERSGDIKH 276
Query: 182 MWADTSLAKEELGWSTQLTIEE 203
D ++ L W+ ++ + E
Sbjct: 277 SCLDQQKLQKHLTWNPRIALNE 298
>UniRef50_Q8THP9 Cluster: DTDP-glucose 4,6-dehydratase; n=3;
Methanosarcina|Rep: DTDP-glucose 4,6-dehydratase -
Methanosarcina acetivorans
Length = 298
Score = 57.2 bits (132), Expect = 3e-07
Identities = 56/188 (29%), Positives = 84/188 (44%), Gaps = 24/188 (12%)
Query: 2 VFSSSCTVYGEPEHLPITET-HPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
V +SS VYG LP E +P + + Y +K E L + + LRYF
Sbjct: 113 VTASSAAVYGNNPELPKRENMYPEPA--SPYAISK-LDGEYLARMFYEEHGLRTTCLRYF 169
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G +DP + ++P FL + GK L ++G DG RD++HV
Sbjct: 170 NVYGPR------QDPKSPYAAVIPIFLERAKAGKD--LVIYG------DGLQSRDFVHVK 215
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ +VAAL H +V+N+ GK V+V EL +T + + + + R GD+
Sbjct: 216 DVVMANVAALE-----HGDGQVFNVAMGKSVTVLELAENIIELTGSSSQIIHAESRAGDV 270
Query: 180 SAMWADTS 187
AD S
Sbjct: 271 RDSRADVS 278
>UniRef50_A5UK04 Cluster: UDP-glucose 4-epimerase; n=2;
Euryarchaeota|Rep: UDP-glucose 4-epimerase -
Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
861)
Length = 309
Score = 57.2 bits (132), Expect = 3e-07
Identities = 53/194 (27%), Positives = 95/194 (48%), Gaps = 26/194 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI--ISLR 58
++FSSS VYG ++P+ E+ T+ Y +K E L+ A ++ + + I+LR
Sbjct: 115 VIFSSSSAVYGNNANMPLKESELMMP-TSPYAASKANCELYLQ---AFEESYGLKSIALR 170
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
YFN G +D ++ ++P F+ + + P+ ++G DG RD+I
Sbjct: 171 YFNVFGPK------QDKNSQYAAVIPNFIDAILNNEHPI--IYG------DGQQTRDFIF 216
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V D+A ++AA ++++ V N+ TG+ ++V L + ++ + YVD+R G
Sbjct: 217 VKDVAKANIAA----AESNYTGPV-NIATGEKLTVNRLYEIIADSMESDLEPVYVDKRKG 271
Query: 178 DISAMWADTSLAKE 191
DI AD E
Sbjct: 272 DIEHSIADIDKMSE 285
>UniRef50_Q2RPP2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Rhodospirillum rubrum ATCC 11170|Rep: NAD-dependent
epimerase/dehydratase - Rhodospirillum rubrum (strain
ATCC 11170 / NCIB 8255)
Length = 328
Score = 56.8 bits (131), Expect = 4e-07
Identities = 50/179 (27%), Positives = 82/179 (45%), Gaps = 18/179 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS V+G+P LP+T PT I + YG K E + ++ LR+F
Sbjct: 126 LVYASSSAVFGDPVALPLTMASPTRPI-SPYGVDKLACEAHAR-VAGGLYGLKSFGLRFF 183
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G G+ ++ ++ + +P+ TVFG DG+ RD+++V D
Sbjct: 184 NVYGE------GQSDDSPYSGVIALFNRKLRDGQPI-TVFG------DGSQSRDFVYVGD 230
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
+ G +AA N + +R V +GTG +V +L V VP+ + R DI
Sbjct: 231 VIEGLLAAWN---EASVRGPVETVGTGCPTTVMDLARTIMEVHGRSVPVVHAPPREADI 286
>UniRef50_Q7P6D7 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
Fusobacterium nucleatum subsp. vincentii ATCC 49256|Rep:
UDP-N-acetylglucosamine 4-epimerase - Fusobacterium
nucleatum subsp. vincentii ATCC 49256
Length = 345
Score = 56.8 bits (131), Expect = 4e-07
Identities = 25/104 (24%), Positives = 51/104 (49%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
DG RDY ++ D+ G + L+ ++ NLG+ + +++ ++V + E K
Sbjct: 236 DGNTSRDYTYIKDIIDGIFKSFEYLNNHQNVYEIINLGSSRKINLLDMVKIIENKLNKKA 295
Query: 168 PLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
LK++D++ GD+ +A A++ L + E+ +F W
Sbjct: 296 KLKFIDKQAGDVDKTFACIDKAEKILNYKVSTKFEDGIENFVNW 339
>UniRef50_A7HBK8 Cluster: NAD-dependent epimerase/dehydratase; n=4;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Anaeromyxobacter sp. Fw109-5
Length = 312
Score = 56.8 bits (131), Expect = 4e-07
Identities = 55/208 (26%), Positives = 87/208 (41%), Gaps = 21/208 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS YG+ + +P E HP +++ YG K E+ ++ A+ +LRY N
Sbjct: 118 SSGGATYGDTDRVPTPEDHPQLPVSH-YGAAKA-ASELYLNVYRANYGIPFTALRYSNVY 175
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G +DP E + F ++ G+ T+FG DG+ RDY+ +
Sbjct: 176 GPR------QDPHGEAGVVAIFCGRLLEGRP--CTIFG------DGSQTRDYVF-----A 216
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
G VA NLL+ N+GTG V EL R + P ++ RLG+
Sbjct: 217 GDVARANLLAAEKRYDGPLNVGTGVETDVNELYAHLARAAGSDRPAEHAPARLGEQKRSC 276
Query: 184 ADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D S A +GW ++ + + + W
Sbjct: 277 IDPSRAGAAVGWRPEVRLADGLRRTFEW 304
>UniRef50_Q7UTP9 Cluster: UDP-glucose 4-epimerase homolog; n=2;
Planctomycetaceae|Rep: UDP-glucose 4-epimerase homolog -
Rhodopirellula baltica
Length = 371
Score = 56.4 bits (130), Expect = 6e-07
Identities = 47/203 (23%), Positives = 93/203 (45%), Gaps = 20/203 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V SS+ VYG ++ E ++ Y K E + + + + LRYFN
Sbjct: 172 VLSSTSAVYGNSPYVAKREDDMPAPLSP-YAAAKLSSENYCQ-VFQREFPIETVVLRYFN 229
Query: 62 PVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G +DP E++ ++P F++ + G++PV ++G DG RD++ V D
Sbjct: 230 VFGPR------QDPKSEYSAVIPRFVSMILSGERPV--IYG------DGQQSRDFVFVRD 275
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A+ ++ A + ++N+G G+ ++ EL++ + + + + R GD+
Sbjct: 276 VANANMLAATVADAAG---GIFNVGRGQRTTLLELLDTLRELLEGDIQPIHEPPRAGDVR 332
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
ADT+ + LG+ + + E
Sbjct: 333 DSLADTNQIRSRLGFEPTVDMTE 355
>UniRef50_Q12UG3 Cluster: NAD-dependent epimerase/dehydratase; n=2;
Euryarchaeota|Rep: NAD-dependent epimerase/dehydratase -
Methanococcoides burtonii (strain DSM 6242)
Length = 299
Score = 56.0 bits (129), Expect = 8e-07
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 21/203 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V+ SS YG P +PI ETHP ++ YG +K E+ + A +R FN
Sbjct: 109 VYFSSAATYGNPLKVPIGETHPQEPLSP-YGASKLAGEKYCIMYNKAYGL-PTTCIRPFN 166
Query: 62 PVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
+DP+ ++ ++ F+ +V+ G P T+FG DG RD+I+V D
Sbjct: 167 IYSPR------QDPSNPYSGVISKFIDKVSGGASP--TIFG------DGEQTRDFIYVRD 212
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ + L + +T I + +N TG+ ++ EL + + ++ Y D GDI
Sbjct: 213 IVD--LVDLMISKRTAIG-ESFNAATGRSTTINELAEIIIDLFGKELKADYKDPLEGDIK 269
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
AD S A E+LG+ ++ + +
Sbjct: 270 HSVADISKA-EKLGFVPKVDLRK 291
>UniRef50_Q6MF46 Cluster: Probable UDP-glucuronat epimerase; n=2;
cellular organisms|Rep: Probable UDP-glucuronat
epimerase - Protochlamydia amoebophila (strain UWE25)
Length = 327
Score = 55.6 bits (128), Expect = 1e-06
Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 22/211 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++++SS +VYG +P + T ++YG TK E M K + I LR+F
Sbjct: 132 LIYASSSSVYGLNTKVPFSLEDRTDQQASLYGVTKKTNELMAKTYHHLFGI-SSIGLRFF 190
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G P G P + + + Q KP+ +F +G RD+ +V D
Sbjct: 191 TVYG--PWGR----PDMAYFSFANAIVQ----GKPI-EIFN------EGKMQRDFTYVDD 233
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ G + A++ T I L V+NLG + V + V + E+ + ++ + GD+
Sbjct: 234 IVEGTIGAID----TEISLGVFNLGNHRPVELLYFVLLLEKELGIEAHKIWLPMQSGDVV 289
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A +AD + ++LG+ +++IEE F +W
Sbjct: 290 ATFADIQESTKQLGFQPKISIEEGLCRFVKW 320
>UniRef50_Q9S1L1 Cluster: SpcI; n=1; Streptomyces netropsis|Rep:
SpcI - Streptoverticillium netropsis
(Streptoverticillium flavopersicus)
Length = 312
Score = 55.6 bits (128), Expect = 1e-06
Identities = 61/201 (30%), Positives = 96/201 (47%), Gaps = 21/201 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNI-ISLRYFNP 62
SS TVY P ET PT ++ YG K E + L+AAD W + + LR+ N
Sbjct: 113 SSGGTVYAPDAPQPFHETAPTRP-SSAYGAAKLAQE---RALTAAD--WTVPVILRFSNL 166
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
GA G+ P + + + + V G+ PV T+ G+ ++ D I D + +
Sbjct: 167 YGA------GQRPRRGYGVIAHWAKAVHEGR-PV-TLIGS--SSRDYLHIDDAVEALLAV 216
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAM 182
HVA+L ++T I L N+G+G VS+ EL FE +P++ R D + +
Sbjct: 217 HRHVASLRA-ARTPITL---NIGSGIPVSLDELHRSFEVAAGHSIPVERRPARSFDRTDV 272
Query: 183 WADTSLAKEELGWSTQLTIEE 203
D + A E LGW+ ++ + E
Sbjct: 273 CLDVTAAAELLGWAPRVPLRE 293
>UniRef50_A5D3C1 Cluster: Nucleoside-diphosphate-sugar epimerases;
n=1; Pelotomaculum thermopropionicum SI|Rep:
Nucleoside-diphosphate-sugar epimerases - Pelotomaculum
thermopropionicum SI
Length = 312
Score = 55.6 bits (128), Expect = 1e-06
Identities = 60/219 (27%), Positives = 97/219 (44%), Gaps = 23/219 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V+ SS VYG +++P+ E HP + ++G K E + + AA + ++ LR
Sbjct: 116 LVYVSSIAVYGNDKYIPMDENHPLEPVL-IHGAVKLAGENFCRTM-AASNGLRMVILRVA 173
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
+ G S + P K FL Q G+ +TV+G DG+ R Y V D
Sbjct: 174 DIYGPRNSRV--SVPIK-------FLLQAMKGEP--ITVYG------DGSDRRTYTFVSD 216
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
V L+LL + V+N+G + VS++EL ++ +K P+ + D
Sbjct: 217 FCEAVV--LSLLRPEAVG-GVFNIGGDECVSMRELALKVKKAAGSKSPVIFQDAPAAG-R 272
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGY 219
+ D+ AK+ LG+ + E RW NPD Y
Sbjct: 273 TLCIDSRKAKKLLGFRPAFDLAEGLALTHRWIRDNPDYY 311
>UniRef50_A3ZYG1 Cluster: Nucleotide sugar epimerase; n=1;
Blastopirellula marina DSM 3645|Rep: Nucleotide sugar
epimerase - Blastopirellula marina DSM 3645
Length = 318
Score = 55.6 bits (128), Expect = 1e-06
Identities = 55/211 (26%), Positives = 92/211 (43%), Gaps = 23/211 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAAD-DKWNIISLRYF 60
+ +SS TVYG +P E P G + YG TK E L L+ A+ + ++ LR F
Sbjct: 124 LLASSSTVYGRGAAIPFAEDAPHGVPASPYGATKRAAE--LLGLTYAELHQTPVVCLRPF 181
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
+ G + L F + G + +FG DGT RD+ HV D
Sbjct: 182 SVYGPR---------LRPDLALTIFAKAIHTGA--TIPLFG------DGTIRRDFTHVSD 224
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ G +AA L+ ++ + NLG + + ++ L+ + E K ++ + R D+
Sbjct: 225 ICDGLIAA---LTAENVIGETINLGHSEPIEMRGLIALLENAFGKKANIERLPERPEDLP 281
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+A+ A+ L + Q+ IE D+ W
Sbjct: 282 VTFANLQKAQRLLNYEPQVPIEVGIRDYVAW 312
>UniRef50_A1RW61 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Thermofilum pendens Hrk 5|Rep: NAD-dependent
epimerase/dehydratase - Thermofilum pendens (strain Hrk
5)
Length = 308
Score = 55.6 bits (128), Expect = 1e-06
Identities = 61/204 (29%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS VYG+ L E + YG TK EE+ + S ++LR F
Sbjct: 113 VVFASSAAVYGDLGGLTAGE-EVDARPKSFYGLTKRVGEELCRFFSGRGVV--CVALRIF 169
Query: 61 NPVGAHPS-GLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G + G+I E A+ L PV V+G DG RD+++V
Sbjct: 170 NVYGEYSRRGVIYE------------FARRVLSGLPV-KVYG------DGNQTRDFVYVG 210
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+A A ++++ +V+N+ +G+ VSV ELV +FE+VT +V + R +I
Sbjct: 211 DVARAFEA---VIAEWSGGFEVFNVASGRCVSVNELVRLFEQVTGKRVGVLREPARPEEI 267
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
A T A LG+ ++EE
Sbjct: 268 RRSCASTEKAARMLGFRASTSLEE 291
>UniRef50_Q3JAZ5 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Nitrosococcus oceani ATCC 19707|Rep: NAD-dependent
epimerase/dehydratase - Nitrosococcus oceani (strain
ATCC 19707 / NCIMB 11848)
Length = 320
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/105 (30%), Positives = 54/105 (51%), Gaps = 4/105 (3%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVT-KAK 166
DG+ RDYIHV DL SG AAL + + + ++L +G+ +V EL ++ +V K
Sbjct: 203 DGSASRDYIHVEDLGSGIAAALEVPVEGS---ETFHLASGRETTVLELADILRQVAGKPH 259
Query: 167 VPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
P+ + R G++S +A A+ G+ + +E+ W W
Sbjct: 260 HPIHFKAARRGEVSRNFATYEKARCAFGFKPKWRLEDGLAATWEW 304
>UniRef50_Q8PXQ4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=3;
Methanomicrobia|Rep: UDP-N-acetylglucosamine 4-epimerase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 334
Score = 55.2 bits (127), Expect = 1e-06
Identities = 56/211 (26%), Positives = 88/211 (41%), Gaps = 22/211 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ +SS +VYG+ ++LP E HPT ++ YG +K E + SLRYF
Sbjct: 122 VINASSSSVYGKVKYLPFDEQHPTEPVSP-YGVSKLAAEHYCRVFYEVYGL-PTTSLRYF 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G + + FT M L +P+ TVFG DG RD+ ++ D
Sbjct: 180 TVYGPR---MRPDLAISIFTRKM-------LANEPI-TVFG------DGEQTRDFTYIED 222
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ A LL KV N+G G +SV L+ +T + + D++ GD
Sbjct: 223 VVE---ANKRLLYNRATDGKVLNIGGGNRISVNNLIENLRFITGSTSEIINADKQKGDTE 279
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A+ L +G++ I + F W
Sbjct: 280 DTLANVDLGNNMIGYTPLFNINKGLNKFVDW 310
>UniRef50_A7HI28 Cluster: NAD-dependent epimerase/dehydratase; n=9;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Anaeromyxobacter sp. Fw109-5
Length = 373
Score = 54.8 bits (126), Expect = 2e-06
Identities = 54/213 (25%), Positives = 89/213 (41%), Gaps = 20/213 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS +VYG E +P +E P + Y TK E M S + + LR+F
Sbjct: 164 LVYASSSSVYGSNEKVPFSEEDPVDHPISFYAATKKANEIMAHAYSHLN-RLPTTGLRFF 222
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G P G ++ P L A+ + +T+F G +RD+ +V D
Sbjct: 223 TVYG--PWGR---------PDMAPILFGRAILRGEPITLFN------HGRMLRDFTYVDD 265
Query: 121 LASGHVAALNLLSQTH--IRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
+ A + + +V N+G + V+++E V + ER KY + GD
Sbjct: 266 VVEVVTALVPRPPEPEDAAPYRVLNVGNDRPVALEEFVAILERHLGRPALRKYAPMQPGD 325
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ A WAD + +G+ + IEE W
Sbjct: 326 VPATWADVRRLQATVGFVPRTPIEEGLRRMTEW 358
>UniRef50_A3I4Y7 Cluster: Nucleoside-diphosphate-sugar epimerase and
GAF domain fusion protein; n=1; Bacillus sp. B14905|Rep:
Nucleoside-diphosphate-sugar epimerase and GAF domain
fusion protein - Bacillus sp. B14905
Length = 308
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/203 (25%), Positives = 94/203 (46%), Gaps = 24/203 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
VF+SS VYG + P+ ET I ++YG K I E + D + I+ R+ N
Sbjct: 112 VFASSAAVYGNSHYPPLEETDVCEPI-SMYGLNK-SIGETYCEKWQKDYRLPILIYRFAN 169
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + GE ++P + + ++ KP T++G DG RD+I+V D+
Sbjct: 170 VFGPRQQ-MQGE------AAVIPSMLKSSMEGKP-FTIYG------DGEQTRDFIYVDDI 215
Query: 122 ASGHVAALNLLSQTHIRLK-VYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
A A + H RL+ +YN+ T + S+ +++ + + + + ++Y R GDI
Sbjct: 216 ADAIYAGV------HARLQGIYNVSTNEAWSLHQVILLLQHLNH-PLEIQYAPAREGDIE 268
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
+ + +GW +++ E
Sbjct: 269 HSFLNNDKLANAIGWRPKISFAE 291
>UniRef50_A2BD24 Cluster: Fcd; n=1; Geobacillus tepidamans|Rep: Fcd
- Geobacillus tepidamans
Length = 308
Score = 54.4 bits (125), Expect = 2e-06
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS+ TVYG I+E I+ +YG K F E++++ + + + R NP
Sbjct: 113 SSAGTVYGNVNKNYISENEILNPIS-IYGLQKAFFEQLIRIKNNEASHFRYLIFRISNPY 171
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
G G+ P K ++P L A+ +P NT IRDYI++ DL+
Sbjct: 172 G----GI--NIPNKN-QGIIPTLVYKAVNNEPF--ELWASINT-----IRDYIYIDDLSE 217
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
+ L I + NLG+GKG S+K+L+++ E + K+ + ++
Sbjct: 218 LIYKTIYL----DIYNETLNLGSGKGTSIKQLISLVEEILGKKITILEKPPIKTNVLKNI 273
Query: 184 ADTSLAKEELGWSTQLTIEE 203
D S +G+ +++IEE
Sbjct: 274 LDISKLVNTVGYEPKISIEE 293
>UniRef50_Q9LIS3 Cluster: UDP-glucuronate 4-epimerase 6; n=40;
Viridiplantae|Rep: UDP-glucuronate 4-epimerase 6 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 460
Score = 54.4 bits (125), Expect = 2e-06
Identities = 65/238 (27%), Positives = 102/238 (42%), Gaps = 29/238 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS +VYG P +E H T ++Y TK EE+ + ++ LR+F
Sbjct: 233 IVWASSSSVYGLNTENPFSEEHRTDQPASLYAATKKAGEEIAHTYNHIYGL-SLTGLRFF 291
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGI-RDYIHVM 119
G P G D F F + GK + Y T D + RD+ ++
Sbjct: 292 TVYG--PWGR--PDMAYFF-----FTKDILHGKSIDI------YRTQDNQEVARDFTYID 336
Query: 120 DLASGHVAALNLLSQT---------HIRLKVYNLGTGKGVSVKELVNVFERV--TKAKVP 168
D+ G V AL+ ++ +L+VYNLG V V LV++ E + TKAK
Sbjct: 337 DIVKGCVGALDTAEKSTGSGGKKRGQAQLRVYNLGNTSPVPVGRLVSILEGLLGTKAKKH 396
Query: 169 LKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDGYPKKTKKT 226
L + R GD+ A+ SLA ++ G+ + F +W P+ K+T
Sbjct: 397 LIKMPRN-GDVPYTHANVSLAYKDFGYKPTTDLAAGLRKFVKWYVGYYGIQPRVKKET 453
>UniRef50_A4FLF3 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: NAD-dependent
epimerase/dehydratase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 324
Score = 54.0 bits (124), Expect = 3e-06
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 25/209 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V +S+ V G+ I+E+ P +T YG TK E +L + A +LR+ N
Sbjct: 127 VLASTNAVVGDIGRGTISESLPLRPLTP-YGATKAACEMLLSGYAGAYGLATC-ALRFTN 184
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G G+ +D + +P L + AL V V+G DG+ RD++HV D+
Sbjct: 185 IYGP---GMGHKD------SFIPRLMRAALAGAGV-EVYG------DGSQSRDFVHVDDV 228
Query: 122 ASGHVAALNL-LSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
G +AA + S T I +G G+ +SV EL+ T +P+ +V + G++
Sbjct: 229 VRGVLAAWDKQYSGTAI------IGAGRSISVTELIEAVRTATGRPLPVTHVPAKNGEMP 282
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFW 209
A+ D + A ELG++ + + + W
Sbjct: 283 AVIVDVAKAGRELGYTPSVELTDGLRTVW 311
>UniRef50_Q9HL87 Cluster: Nucleotide sugar epimerase related
protein; n=4; Euryarchaeota|Rep: Nucleotide sugar
epimerase related protein - Thermoplasma acidophilum
Length = 307
Score = 54.0 bits (124), Expect = 3e-06
Identities = 53/206 (25%), Positives = 100/206 (48%), Gaps = 24/206 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++S+ ++Y + + P +T+ Y +Y E + +L + NI ++R+F
Sbjct: 112 VVYASTSSIYNGVKPPHREDVIPF--VTDFYTEARYATER-ISELYSKLYGINISAMRFF 168
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
+ G + E K+F NL+ F+ + GK+PV ++G DG RD++ V
Sbjct: 169 SVYGYN------ERSKKKFANLVSQFIWDMHDGKQPV--IYG------DGEQKRDFVFVD 214
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD- 178
D+ V AL + + VYN+GTGK S+ ELV + KYV+ +
Sbjct: 215 DV----VDALINAAVYNTGFNVYNVGTGKNYSLNELVQKLNDHMHTDIKAKYVENPMAKT 270
Query: 179 -ISAMWADTSLAKEELGWSTQLTIEE 203
+ ADT ++E++ + +++++E
Sbjct: 271 YVHETLADTKKSEEKIKFKAKISLDE 296
>UniRef50_Q2WB63 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=2; Alphaproteobacteria|Rep:
Nucleoside-diphosphate-sugar epimerase -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 333
Score = 53.6 bits (123), Expect = 4e-06
Identities = 60/220 (27%), Positives = 95/220 (43%), Gaps = 23/220 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V+ SS VYG + E VYG K E K ++ +R FN
Sbjct: 117 VYCSSSEVYGNGRDSLLNEDRTVCEPVTVYGAAKLAGELYAKAYHRTYGLPTVV-VRPFN 175
Query: 62 PVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G E + ++P FL +V G P T+FG DG+ RD+ +V +
Sbjct: 176 SYGPR------EHYKGQRAEVIPRFLIRVLNGLPP--TIFG------DGSAGRDFTYVTE 221
Query: 121 LASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFERVT-KAKVPLKYVDRRLGD 178
A G L + +Q + + N+ G+ V+VKE+ R+ + + Y R GD
Sbjct: 222 TARG----LAMAAQCDALVGREINIAYGRMVTVKEVAESITRLCQRPDIAPSYGPGRPGD 277
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTM-NPD 217
+ A+ ADT+LA+ LG+ ++ E+ + W T +PD
Sbjct: 278 VKALHADTALARSLLGFKAEIGFEQGLETYIDWFTRHHPD 317
>UniRef50_Q67G37 Cluster: Probable dTDP-4-keto-6-deoxyhexose
reductase; n=1; Streptomyces griseoruber|Rep: Probable
dTDP-4-keto-6-deoxyhexose reductase - Streptomyces
griseoruber
Length = 325
Score = 53.6 bits (123), Expect = 4e-06
Identities = 60/222 (27%), Positives = 90/222 (40%), Gaps = 24/222 (10%)
Query: 1 MVFSSSCTVYGEPEH-LPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+V S YGE H + E +P T Y R+K + D + A + LR
Sbjct: 121 LVHLGSILEYGETPHGTRVDERYPPRP-TTAYTRSKLAGSTAVLDAARAGTV-DATVLRL 178
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G HPS P L+ LA+ P++ V T+ RD++ V
Sbjct: 179 TNVCGPHPS------PQSLPGKLVELLAEAVRSGGPMI-VGVTEAR-------RDFVDVR 224
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG-D 178
D+A + A + + N+G+G+ V ++ELV +F V + + +RR
Sbjct: 225 DVAEAVLRAAGPGATG----RAVNIGSGRAVGIRELVRLFVTVAGSDPGILREERRPNTS 280
Query: 179 ISAMW--ADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPDG 218
+ W AD LA E LGW + + D WR PDG
Sbjct: 281 LGGTWTCADIRLAGELLGWRPRTGLAASLRDMWRTAARTPDG 322
>UniRef50_Q2NIA3 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Putative
UDP-glucose 4-epimerase - Methanosphaera stadtmanae
(strain DSM 3091)
Length = 315
Score = 53.6 bits (123), Expect = 4e-06
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 24/200 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ +SS VYGE E LP ET P ++ Y +K +E + LRYF
Sbjct: 117 VISASSAAVYGETEVLPNVETLPLQPLSP-YAVSKALLE-LYSYTFTQTYHLPTACLRYF 174
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G + P ++ ++P F++ + + PV ++G DG RD+I+V
Sbjct: 175 NVFGPRQKA---DSP---YSGVIPKFISALLNNETPV--IYG------DGEQTRDFIYVK 220
Query: 120 DLA-SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
++A + + A+N ++ V+N+ GK ++ EL+ + + KY+ ++ GD
Sbjct: 221 NIAKANYEVAINDVTG------VFNIAHGKTTTINELLEIICEIMGYDCNPKYLPQKDGD 274
Query: 179 ISAMWADTSLAKEELGWSTQ 198
I AD S A+E G+ ++
Sbjct: 275 IRDSVADISKAEETFGFKSE 294
>UniRef50_Q67RC7 Cluster: UDP-glucose 4-epimerase; n=1;
Symbiobacterium thermophilum|Rep: UDP-glucose
4-epimerase - Symbiobacterium thermophilum
Length = 292
Score = 53.2 bits (122), Expect = 5e-06
Identities = 56/211 (26%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V +S+ +VYGE +P E P ++ YG TK E++ DL ++LRYF
Sbjct: 101 VLASTSSVYGEVP-MPAREDGPAMPVSP-YGLTKLAAEKLC-DLYGRTAGIPWVALRYFT 157
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P F+ AL +P+ ++G DG+ +RD+ +V D
Sbjct: 158 VYGPR------QRPDMAFSRWF----NAALDGEPI-QIYG------DGSQLRDFTYVADA 200
Query: 122 ASG-HVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ AALN + I N+G G V+V+E + + +T + ++ + GD+
Sbjct: 201 VTATQRAALNPVVGVPI-----NVGGGSAVTVREAIRLIAAITGRPIRIRQLPPAPGDMR 255
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
ADT E+G+ +EE +RW
Sbjct: 256 ETRADTERLWREVGFRPSTPLEEGLWQQYRW 286
>UniRef50_Q02BA7 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
NAD-dependent epimerase/dehydratase precursor -
Solibacter usitatus (strain Ellin6076)
Length = 651
Score = 53.2 bits (122), Expect = 5e-06
Identities = 40/130 (30%), Positives = 60/130 (46%), Gaps = 9/130 (6%)
Query: 95 PVLTVFGTDYNTP---DGTGIRDYIHVMDLASGHV-AALNLLSQTHIRLKVYNLGTGKGV 150
P L V G + P D RD+I++ D V ALNL + + +N+GTG
Sbjct: 189 PSLIVKGLNGEYPPLVDPAVSRDFIYIDDACEAFVDCALNLTPTWYG--ESFNIGTGTST 246
Query: 151 SVKELVNVFERVTKAKV--PLKYVDRRLGDISAMW-ADTSLAKEELGWSTQLTIEEMCTD 207
++ EL + + + P + +RL D +++W AD S A + LGWS + TI E
Sbjct: 247 TIGELAEIARDLLHIDISPPFSTMPKRLWDTTSVWCADASRATQHLGWSPRTTIREGLQR 306
Query: 208 FWRWQTMNPD 217
W PD
Sbjct: 307 TIEWYRSLPD 316
>UniRef50_Q0YTU0 Cluster: NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid dehydrogenase/isomerase; n=1; Chlorobium
ferrooxidans DSM 13031|Rep: NAD-dependent
epimerase/dehydratase:3-beta hydroxysteroid
dehydrogenase/isomerase - Chlorobium ferrooxidans DSM
13031
Length = 325
Score = 52.8 bits (121), Expect = 7e-06
Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 25/211 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F+S+ T+YG LP++ET +T VY K F E+ L + ++ +SLR
Sbjct: 116 VIFTSTVTLYGLTTCLPVSETQTPNPVT-VYDIHKLFAEQQLTQATRL-GLFDSVSLRLA 173
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G PS + P + N + A G+ ++++G DG IRDY+ + D
Sbjct: 174 NVYG--PSSSVSSSPDRGILNRVALRA--LQGQN--ISLYG------DGNYIRDYVFLDD 221
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKE----LVNVFERVTKAKVPLKYVDRRL 176
+ A L + + I+ +V+N+G+G G +++ +V+ E+VT +V L+ +
Sbjct: 222 VVR---AILLAGAVSGIQGEVFNIGSGVGTTLRRAFELVVDQAEQVTGKRVALESIMWPS 278
Query: 177 G----DISAMWADTSLAKEELGWSTQLTIEE 203
G + A + GW ++IE+
Sbjct: 279 GTDPIEFRNFIAQNEKFSKAAGWEPLVSIED 309
>UniRef50_A0JYE3 Cluster: NAD-dependent epimerase/dehydratase; n=16;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Arthrobacter sp. (strain FB24)
Length = 364
Score = 52.4 bits (120), Expect = 9e-06
Identities = 51/208 (24%), Positives = 87/208 (41%), Gaps = 19/208 (9%)
Query: 13 PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIG 72
P + +ET P +VYG TK E +L+ + + +I LR N G G
Sbjct: 175 PVAMKASETFPAP--VSVYGATKLAQENVLQAWAKSYGVETVI-LRLQNVYGP------G 225
Query: 73 EDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLL 132
+ +T +M ++A+G K + DG RD+I + D+AS VA
Sbjct: 226 QSLINPYTGIMSLFCRMAMGGKSIPLY-------EDGEVRRDFILIDDVASAIVAGA--- 275
Query: 133 SQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEE 192
T ++ + ++G+G+ ++ + KA R GD+ WAD + A++
Sbjct: 276 VSTTVQAEPMDIGSGEFQTIGTAAKLIAEHYKAPASHVTGQYRQGDVRHAWADITAAEKV 335
Query: 193 LGWSTQLTIEEMCTDFWRWQTMNPDGYP 220
LGW+ + + + W PD P
Sbjct: 336 LGWTPKYNLAQGIERLATWIDAQPDVKP 363
>UniRef50_Q93N66 Cluster: Dehydratase-like protein; n=14; cellular
organisms|Rep: Dehydratase-like protein - Coxiella
burnetii
Length = 344
Score = 52.0 bits (119), Expect = 1e-05
Identities = 54/203 (26%), Positives = 86/203 (42%), Gaps = 26/203 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V+++S + YG + +P E HP Y +KY EE + S+R F
Sbjct: 118 LVYAASSSCYGLAD-VPTREDHPIAP-QYPYALSKYLGEEAAFHWFQVYGL-PVNSIRIF 174
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G T + + + L KP TV G DGT RD+++V D
Sbjct: 175 NAYGTRVR------TTGVYGAVFGVFFKQKLADKP-FTVVG------DGTQRRDFLYVTD 221
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A + A ++T + +NLG G S+ LV + ++Y+ +R G+
Sbjct: 222 VARAFLKA----AETRKVGETWNLGAGNPQSINRLVELIGG------EVEYIPKRPGEPD 271
Query: 181 AMWADTSLAKEELGWSTQLTIEE 203
WAD S K +LGW +T +
Sbjct: 272 CTWADISKIKRDLGWEPTITFAD 294
>UniRef50_Q7D561 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=20; Bacteria|Rep: NAD-dependent
epimerase/dehydratase family protein - Mycobacterium
tuberculosis
Length = 322
Score = 52.0 bits (119), Expect = 1e-05
Identities = 56/200 (28%), Positives = 83/200 (41%), Gaps = 20/200 (10%)
Query: 4 SSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPV 63
SS ++YG P P ET PT + Y K E L ++ L +
Sbjct: 128 SSGGSIYGTPPEYPTPETAPTDP-ASPYAAGKVAGEIYLNTFR------HLYGLDCSHIA 180
Query: 64 GAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
A+ G +DP E ++ AQ L KP VFG DGT RDY+ V D+
Sbjct: 181 PANVYGP-RQDPHGE-AGVVAIFAQALLSGKPT-RVFG------DGTNTRDYVFVDDVVD 231
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMW 183
V + + L+ +N+GTGK S ++L + ++ RLGD+
Sbjct: 232 AFV---RVSADVGGGLR-FNIGTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSC 287
Query: 184 ADTSLAKEELGWSTQLTIEE 203
D LA+ LGW Q+ + +
Sbjct: 288 LDIGLAERVLGWRPQIELAD 307
>UniRef50_Q112T2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Trichodesmium erythraeum IMS101|Rep: NAD-dependent
epimerase/dehydratase - Trichodesmium erythraeum (strain
IMS101)
Length = 301
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 113 RDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY- 171
RD+IHV D+ ++ L S+ + Y +GTGK S+++L+ + + + + + LK+
Sbjct: 196 RDFIHVEDVVLAYLLLLEKESKPSQYYQEYEVGTGKATSLRQLLEMLKELMQVQTELKFG 255
Query: 172 -VDRRLGDISAMWADTSLAKEELGWSTQLTIEE 203
+ +R G+I ADT EE+GW +++E
Sbjct: 256 ALPQRRGEIMFSQADTKTI-EEIGWYPAKSLKE 287
>UniRef50_A7CY79 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Opitutaceae bacterium TAV2|Rep: NAD-dependent
epimerase/dehydratase - Opitutaceae bacterium TAV2
Length = 349
Score = 52.0 bits (119), Expect = 1e-05
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 19/215 (8%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+ +SS +VYG P ET P + Y +K E++ + + + LR F
Sbjct: 142 ILASSSSVYGANPKTPFAETDPIQRTLSPYAASKLAAEQLCSNYAHLHGL-RCLCLRLFT 200
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + P F A + G+ + ++G DGT RDY +V D+
Sbjct: 201 VYGPR------QRPDLAIAR---FTAAIRDGRP--IDLYG------DGTTARDYTYVDDI 243
Query: 122 ASGHVAA-LNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
G +AA + +++NLG ++ ELV + E ++ + GD+
Sbjct: 244 IQGLLAAGRRTATLPPATFEIFNLGESATTTLNELVTLIENALGRPALIRRQPEQPGDVP 303
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
+AD S A+ LG++ + + RW N
Sbjct: 304 RTYADISKARRLLGYAPATLPADGIRKYIRWLETN 338
>UniRef50_UPI0000384B3D Cluster: COG0451:
Nucleoside-diphosphate-sugar epimerases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0451:
Nucleoside-diphosphate-sugar epimerases -
Magnetospirillum magnetotacticum MS-1
Length = 315
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/146 (29%), Positives = 64/146 (43%), Gaps = 15/146 (10%)
Query: 75 PTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNL-LS 133
P + T L+P + AL KP+ T +G RDY++ DL + L L +
Sbjct: 176 PWERITRLIPQIIFSALDGKPI--------RTTEGRQTRDYLYADDL----IDLLELAVD 223
Query: 134 QTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY--VDRRLGDISAMWADTSLAKE 191
+ + YN G G+GV V+ +V+ + V + + R +I M AD S AK
Sbjct: 224 KPRDGWRAYNAGAGEGVPVRTIVSTVLELMGNPVEGLFGAIPTRPDEIMEMTADISRAKA 283
Query: 192 ELGWSTQLTIEEMCTDFWRWQTMNPD 217
E GW ++ E T W T N D
Sbjct: 284 EFGWQPTTSLREGLTRTVGWFTTNAD 309
>UniRef50_Q47GM1 Cluster: NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid dehydrogenase/isomerase; n=2;
Betaproteobacteria|Rep: NAD-dependent
epimerase/dehydratase:3-beta hydroxysteroid
dehydrogenase/isomerase - Dechloromonas aromatica
(strain RCB)
Length = 325
Score = 51.6 bits (118), Expect = 2e-05
Identities = 56/202 (27%), Positives = 96/202 (47%), Gaps = 20/202 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS +VYG E LP+ ET T I++ +G K IE+ L+ L + R
Sbjct: 119 IVFTSSSSVYGVHEQLPVPETASTDPISS-HGIHKLAIEKYLR-LYQYHHGLDCKIARLS 176
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
NP G P I D + F + + + G+ + V G DG IRD+ ++ D
Sbjct: 177 NPYG--PGQSI--DGRQGFVAIA--IGHILRGQP--IPVRG------DGEIIRDFAYIDD 222
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ V AL +L+ + R ++N+G+G G S+ E++ + V + + R DI
Sbjct: 223 V----VEALMVLASSESREALFNIGSGIGYSLNEVIARLRTLCAIPVEASHTESRYVDIP 278
Query: 181 AMWADTSLAKEELGWSTQLTIE 202
D S + L ++++++E
Sbjct: 279 KSVLDVSRERYVLRKTSKISLE 300
>UniRef50_Q2FKD1 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=13; Staphylococcus aureus|Rep: NAD-dependent
epimerase/dehydratase family protein - Staphylococcus
aureus (strain USA300)
Length = 326
Score = 51.6 bits (118), Expect = 2e-05
Identities = 51/215 (23%), Positives = 99/215 (46%), Gaps = 21/215 (9%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+F+SS VYG+ LP ++ ++ Y KY+ E + + + + +++FN
Sbjct: 120 IFASSAAVYGDLPDLPKSDQSLILPLSP-YAIDKYYGERTTLNYCSLYNIPTAV-VKFFN 177
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G +DP +++ ++ + KP T FG DG RD+++V D+
Sbjct: 178 VFGPR------QDPKSQYSGVISKMFDSFEHNKP-FTFFG------DGLQTRDFVYVYDV 224
Query: 122 ASGHVAALNLLSQTHIRL-KVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
V ++ L+ + + YN+GTG ++ E+ + + V ++ + R GDI
Sbjct: 225 ----VQSVRLIMEHKDAIGHGYNIGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIK 280
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
+AD S K LG+ + T+E D++ ++ N
Sbjct: 281 HSYADISNLK-ALGFVPKYTVETGLKDYFNFEVDN 314
>UniRef50_Q3VNH5 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Pelodictyon phaeoclathratiforme
BU-1|Rep: NAD-dependent epimerase/dehydratase precursor
- Pelodictyon phaeoclathratiforme BU-1
Length = 309
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/96 (32%), Positives = 54/96 (56%), Gaps = 10/96 (10%)
Query: 112 IRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY 171
IRDY+HV D+A V AL + ++N+G+GK SV E++ + ++ + +P++
Sbjct: 206 IRDYVHVSDVAQALVLAL----KNPAPFDIFNIGSGKKTSVMEILALIRTISGSDLPIQS 261
Query: 172 VD----RRLGDISAMWADTSLAKEELGWSTQLTIEE 203
+ + L D + D S A+++LGW QL +EE
Sbjct: 262 EELPENQTLPDCCLL--DISKAEQKLGWRAQLHLEE 295
>UniRef50_Q11EL9 Cluster: NAD-dependent epimerase/dehydratase; n=18;
Bacteria|Rep: NAD-dependent epimerase/dehydratase -
Mesorhizobium sp. (strain BNC1)
Length = 369
Score = 51.6 bits (118), Expect = 2e-05
Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 19/195 (9%)
Query: 19 TETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKE 78
T+ + ++Y TKY E + A ++LR FN G G+ +
Sbjct: 168 TDEEKPVELASIYALTKYAQERAVLIFGEAYPV-EAVALRLFNVFGP------GQALSNP 220
Query: 79 FTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIR 138
+T ++ A +P L +F DG RD++HV D+A AL S+T
Sbjct: 221 YTGVLANFASRLANNQPPL-IF------EDGRQKRDFVHVRDVARAFRLALE--SKTAAG 271
Query: 139 LKVYNLGTGKGVSVKELVNVF-ERVTKAKVPLKYVDR-RLGDISAMWADTSLAKEELGWS 196
+V N+G+G +++++ + + + A++ + +++ R GDI +AD S A + LG+
Sbjct: 272 -QVINVGSGNAYTIQQVAEILADAMGLAEIKPEIMNKMRSGDIRHCFADISKAHDLLGFE 330
Query: 197 TQLTIEEMCTDFWRW 211
Q +E+ +F W
Sbjct: 331 PQHRLEDTVAEFAEW 345
>UniRef50_O26480 Cluster: UDP-glucose 4-epimerase homolog; n=3;
cellular organisms|Rep: UDP-glucose 4-epimerase homolog
- Methanobacterium thermoautotrophicum
Length = 316
Score = 51.6 bits (118), Expect = 2e-05
Identities = 52/204 (25%), Positives = 89/204 (43%), Gaps = 24/204 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +S+ VYG +P+ E ++ Y +K E + D +SLRYF
Sbjct: 116 VVNASTSAVYGNNPEIPLREDARPMPLSP-YAVSKVTGEYYCQVFE--DQGLETVSLRYF 172
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
N G + P ++ ++P F+ + G+ P ++G DG RD+I+V
Sbjct: 173 NVYGPR------QRPDSQYAAVIPRFIDALLSGRSP--EIYG------DGEQSRDFIYV- 217
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
G V N+ VYN+ G V+V L ++ + ++ +Y+D R GD+
Sbjct: 218 ----GDVVRANIFLAESRGSGVYNVAGGSSVTVNRLFDIISGILESDAEPEYLDERPGDV 273
Query: 180 SAMWADTSLAKEELGWSTQLTIEE 203
ADTS G+ ++ +EE
Sbjct: 274 RHSLADTS-RLAAAGFRPEVGLEE 296
>UniRef50_Q2AZL1 Cluster: NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid dehydrogenase/isomerase:Polysaccharide
biosynthesis protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase; n=3; Bacillus
cereus group|Rep: NAD-dependent
epimerase/dehydratase:3-beta hydroxysteroid
dehydrogenase/isomerase:Polysaccharide biosynthesis
protein CapD:dTDP- 4-dehydrorhamnose
reductase:Nucleotide sugar epimerase - Bacillus
weihenstephanensis KBAB4
Length = 307
Score = 51.2 bits (117), Expect = 2e-05
Identities = 45/178 (25%), Positives = 84/178 (47%), Gaps = 25/178 (14%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++FSSS VYG+ +P E + + YG+ K E+ LK+ A++ + + +RYF
Sbjct: 104 LLFSSSSEVYGDGVSVPFKE-NDVKIPKSAYGKAKLMSEDFLKEY--ANNSFKVRVVRYF 160
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N + G + F + FL Q G+ +T++G DG IR + ++ D
Sbjct: 161 N--------VYGSQQNENFV-ISKFLKQAHNGEN--MTIYG------DGQQIRCFSYISD 203
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
+ +G + A + +N+G K +S++EL + K +++++ LGD
Sbjct: 204 IVNGTILAFEYERE---NFADFNIGNNKPISMEELAGKINELMGNKSEIEFLN--LGD 256
>UniRef50_A3H793 Cluster: NAD-dependent epimerase/dehydratase; n=3;
Archaea|Rep: NAD-dependent epimerase/dehydratase -
Caldivirga maquilingensis IC-167
Length = 325
Score = 51.2 bits (117), Expect = 2e-05
Identities = 62/222 (27%), Positives = 96/222 (43%), Gaps = 35/222 (15%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS TVYG+ + LP E HP I +VYG TK E++ D + +++LRY
Sbjct: 122 IVFASSSTVYGDAKVLPTPEDHPIIPI-SVYGATK-AAGEIILDTYSRLYGIRVVNLRYA 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N VG P + F ++ + L V G DG+ + Y++V D
Sbjct: 180 NIVG----------PRSRHGVIYDFYIKLTRNPRE-LEVLG------DGSQRKSYLYVDD 222
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVN-VFER--------VTKAKVPLKY 171
+ N L ++ + +N+G V+V ++ V E VT+A P
Sbjct: 223 AVDASLFLFNKLINGSLQEQAFNVGNKDWVTVMDIARIVIEELGLRNVNIVTRAMTP--- 279
Query: 172 VDRR--LGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
D R LGD+ M D +LGWS + + + RW
Sbjct: 280 -DGRGWLGDVKYMLLDVD-KLSKLGWSPRYSSADAVRLTIRW 319
>UniRef50_Q8A826 Cluster: CDP-abequose synthase; n=1; Bacteroides
thetaiotaomicron|Rep: CDP-abequose synthase -
Bacteroides thetaiotaomicron
Length = 296
Score = 50.8 bits (116), Expect = 3e-05
Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 105 NTPDGTGIRDYIHVMDLASGH---VAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFER 161
N G I D+IH+ D++ ++ LNLL T + ++Y LGTGKG S++EL + E
Sbjct: 187 NFTKGEQINDFIHINDVSDFFYVLLSNLNLLEDT-MYTQLY-LGTGKGTSIRELSYIIET 244
Query: 162 VTKAKVPLKY--VDRRLGDISAMWADTSLAKEELGWSTQLTIEE 203
V K KV + + R DI A S + L W T++++EE
Sbjct: 245 VYKQKVNANWGGLSYRPYDIMYAVAPISRNLDLLKWKTKISLEE 288
>UniRef50_Q1AWM7 Cluster: NAD-dependent epimerase/dehydratase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
NAD-dependent epimerase/dehydratase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 331
Score = 50.8 bits (116), Expect = 3e-05
Identities = 41/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)
Query: 85 FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTH-IRLKVYN 143
F+ + A G+ VL ++G DGT RD+I++ DL V AL L + + +V+
Sbjct: 203 FIRRAARGE--VLEIYG------DGTQTRDFIYIDDL----VRALRLAATAGGVGGEVFQ 250
Query: 144 LGTGKGVSVKELVNVFERVTKAK----VPLKYVDRRLGDISAMWADTSLAKEELGWSTQL 199
+ TG SV E+V + V A V ++ R GD++ +ADTS A+ LGW ++
Sbjct: 251 IATGSETSVGEVVELLLPVLAAAGIKGVRVERASPRPGDVARNYADTSKARRLLGWRAEV 310
Query: 200 TIEE 203
+EE
Sbjct: 311 GLEE 314
>UniRef50_Q0C421 Cluster: Putative GDP-6-deoxy-D-lyxo-4-hexulose
reductase; n=1; Hyphomonas neptunium ATCC 15444|Rep:
Putative GDP-6-deoxy-D-lyxo-4-hexulose reductase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 324
Score = 50.8 bits (116), Expect = 3e-05
Identities = 40/162 (24%), Positives = 68/162 (41%), Gaps = 17/162 (10%)
Query: 49 DDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKP-VLTVFGTDYNTP 107
+D N + R FN G G+ P + +AQ+ G P V+ V D
Sbjct: 164 NDGLNAVRFRAFNHTGP------GQSPDYVVASFAAQIAQIIAGDHPPVIRVGNLD---- 213
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
+RD++ V D+ G+ AL + V+NL +G S++ ++N + +
Sbjct: 214 ---AMRDFVDVRDVVRGYRLALET-ELDPVSEGVFNLASGTPRSIRSILNTLIDIAGVDI 269
Query: 168 PLKYVDRRL--GDISAMWADTSLAKEELGWSTQLTIEEMCTD 207
++ +L D+ W D + A+ ELGW L E+ D
Sbjct: 270 AIETDPAKLRKNDVPRTWGDANRARTELGWVPYLAFEQTLVD 311
>UniRef50_Q8GJ79 Cluster: DTDP glucose-4,6-dehydrogenase; n=11;
Bacteria|Rep: DTDP glucose-4,6-dehydrogenase -
Mycobacterium smegmatis
Length = 377
Score = 50.4 bits (115), Expect = 4e-05
Identities = 46/176 (26%), Positives = 77/176 (43%), Gaps = 17/176 (9%)
Query: 28 TNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLA 87
TNVY TK E +L +AA D + LR N G G+ T +T ++ A
Sbjct: 203 TNVYAATKLAQEHVLTAWTAAHDT-KLSVLRLQNVYGP------GQSLTNSYTGIVALFA 255
Query: 88 QVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTG 147
++A ++ L V+ DG +RD++ + D+ AA+ + + ++G+G
Sbjct: 256 RLAR-EQQTLEVY------EDGNILRDFVFIEDVVEALYAAIRRPADQR---RCLDIGSG 305
Query: 148 KGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEE 203
G S+ L + A P R GD+ A D A+ EL W + T+++
Sbjct: 306 VGSSIHALAQKVAGICGAPTPKVVGKFRDGDVRAASCDIEPARMELDWRPKWTLDD 361
>UniRef50_A6UU12 Cluster: ADP-L-glycero-D-manno-heptose-6-epimerase;
n=2; cellular organisms|Rep:
ADP-L-glycero-D-manno-heptose-6-epimerase -
Methanococcus aeolicus Nankai-3
Length = 305
Score = 50.4 bits (115), Expect = 4e-05
Identities = 51/216 (23%), Positives = 87/216 (40%), Gaps = 22/216 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+++SS YG+ E P E + G N+YG +K+ + M K +I+ LRYFN
Sbjct: 107 IYASSAATYGDAES-PQKEEY-AGRPNNIYGFSKWICDCMAKKYMEKYPDSHIVGLRYFN 164
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G + K + + Q+ GK P + +G RD ++V
Sbjct: 165 VFGPRE-----QYKGKMASMVWQLAKQMVEGKNPRIFKWGEQK--------RDQVYVK-- 209
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI-- 179
++ +NLL+ + N G+G VS ++ V V +Y+D +
Sbjct: 210 ---NIVQINLLALDAKESCIVNAGSGNAVSFNHIIEVLNDVLGFDYEPEYIDNPYEEFYQ 266
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
AD + AK+ L + + E+ D+ W N
Sbjct: 267 DFTQADLTNAKKYLDYEPKWNFEDGVKDYVEWLKEN 302
>UniRef50_Q3ANB2 Cluster: Putative sugar nucleotide
epimerase/dehydratase; n=1; Synechococcus sp.
CC9605|Rep: Putative sugar nucleotide
epimerase/dehydratase - Synechococcus sp. (strain
CC9605)
Length = 287
Score = 50.0 bits (114), Expect = 5e-05
Identities = 53/180 (29%), Positives = 87/180 (48%), Gaps = 28/180 (15%)
Query: 29 NVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMP-FLA 87
+VY TK E +LK+L + D WNI LR+ N G G+ +T ++ F +
Sbjct: 119 SVYASTKLMQELLLKNLCSNMD-WNI--LRFQNVYGP------GQSLNNPYTGVLSIFCS 169
Query: 88 QVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTG 147
Q+ GK L ++ DG RD+I++ D+ VAA+N S ++ N+G+G
Sbjct: 170 QIKDGK--TLEIY------EDGEIFRDFIYIDDVVRSLVAAINASSG-----EIINIGSG 216
Query: 148 KGVSVKELVNVFERVTKAK---VPLKYVDR-RLGDISAMWADTSLAKEEL-GWSTQLTIE 202
S+ ++VN+ R+ + K K + R GDI AD + A + L W ++ +E
Sbjct: 217 ISTSIIDIVNILCRLAEEKGFHPEYKITGKFRDGDIRFAQADITKAFQSLNSWEPKIPLE 276
>UniRef50_Q012L1 Cluster: DTDP-glucose 4-6-dehydratase-like protein;
n=1; Ostreococcus tauri|Rep: DTDP-glucose
4-6-dehydratase-like protein - Ostreococcus tauri
Length = 430
Score = 50.0 bits (114), Expect = 5e-05
Identities = 53/206 (25%), Positives = 90/206 (43%), Gaps = 23/206 (11%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAAD----DKWNIISL 57
+ +S+ VYG+P P E++ G++ + R Y + + A D +I
Sbjct: 220 LLTSTSEVYGDPLEHPQKESY-WGNVNPIGERACYDEGKRCAETLAFDYHREHGLDIRVA 278
Query: 58 RYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIH 117
R FN G + D + +N F+AQ G K LTV+G DG+ R + +
Sbjct: 279 RIFNTYGPR----MAMDDGRVVSN---FVAQALRGDK--LTVYG------DGSQTRSFQY 323
Query: 118 VMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLG 177
V DL +G +A L+ + NLG ++ EL + ++Y +
Sbjct: 324 VSDLVAGLIA---LMDNEDGFIGPVNLGNPGEFTMNELAEKVREIVNPAAEIEYCENTAD 380
Query: 178 DISAMWADTSLAKEELGWSTQLTIEE 203
D S D S+A+E+L W ++T++E
Sbjct: 381 DPSRRKPDISVAREKLRWEPKVTLDE 406
>UniRef50_Q5UXR1 Cluster: UDP-glucose 4-epimerase; n=2;
Halobacteriaceae|Rep: UDP-glucose 4-epimerase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 331
Score = 49.6 bits (113), Expect = 7e-05
Identities = 54/214 (25%), Positives = 94/214 (43%), Gaps = 26/214 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F S V G+P+ PIT HP + N YGRTK E ++ + AD +
Sbjct: 120 LIFPFSMAVIGDPQEFPITVDHPRDPL-NWYGRTKLLNERDVE--TYADGAFPAHQFMIS 176
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G+H + G+ +K ++ F AL + LTV+ GT R++IHV D
Sbjct: 177 NLYGSHE--IDGQTVSK--GTVINFFVNRALAGE-TLTVY------EPGTQSRNFIHVKD 225
Query: 121 LASGHVAA----LNLLSQTHIRLKVYNLGTGKGVSV----KELVNVFERVTKAKVPLKYV 172
+A +V + L L + ++ Y + + + SV K + ++ + ++ V
Sbjct: 226 VARAYVDSCERLLEQLDRGETGVEKYEIASDEDPSVHTVAKLVRDIAADIADIDADVELV 285
Query: 173 DRRLGD----ISAMWADTSLAKEELGWSTQLTIE 202
+ GD + + DT LGW+ + +E
Sbjct: 286 ENPRGDDETLVDSFTVDTGRTTAALGWTPEHDVE 319
>UniRef50_P39630 Cluster: Spore coat polysaccharide biosynthesis
protein spsJ; n=26; cellular organisms|Rep: Spore coat
polysaccharide biosynthesis protein spsJ - Bacillus
subtilis
Length = 315
Score = 49.6 bits (113), Expect = 7e-05
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
DG IRD++ D H A+ L+ + +VYN+G G + KEL +V + +
Sbjct: 210 DGLQIRDWLFAED----HCRAIKLILEKGTDGEVYNIGGGNERTNKELASVILKHLGCEE 265
Query: 168 PLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
+V+ R G + S K ELGW ++T EE +W T N
Sbjct: 266 LFAHVEDRKGHDRRYAINASKLKNELGWRQEVTFEEGIARTIQWYTDN 313
>UniRef50_Q31EZ4 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=1; Thiomicrospira crunogena XCL-2|Rep:
NAD-dependent epimerase/dehydratase family protein -
Thiomicrospira crunogena (strain XCL-2)
Length = 309
Score = 49.2 bits (112), Expect = 9e-05
Identities = 49/189 (25%), Positives = 83/189 (43%), Gaps = 25/189 (13%)
Query: 17 PITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPT 76
P+ E P N Y +TK E +LK S D + + R F+P G
Sbjct: 129 PVDENAPIVPF-NFYAKTKLAFETVLKTHS---DTMMVNTFRLFSPYGE----------- 173
Query: 77 KEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALN-LLSQT 135
K+ L+P + Q AL G +G D I+V D+ SG++ A+ +LS T
Sbjct: 174 KDNQKLVPMIIQKALK--------GEAIELSEGLQKIDLIYVEDIVSGYMKAVERILSDT 225
Query: 136 -HIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISAMWADTSLAKEELG 194
+V+NLG+G +S++++V++ E+ + + + DI +AD + L
Sbjct: 226 FQPEYEVFNLGSGVALSIRDVVSIVEQKIGKPLKKTWGEASEVDIPIAYADITKLARILH 285
Query: 195 WSTQLTIEE 203
W + T +
Sbjct: 286 WKPEYTASQ 294
>UniRef50_Q70PA0 Cluster: Putative uncharacterized protein; n=1;
Melittangium lichenicola|Rep: Putative uncharacterized
protein - Melittangium lichenicola
Length = 320
Score = 49.2 bits (112), Expect = 9e-05
Identities = 52/211 (24%), Positives = 86/211 (40%), Gaps = 18/211 (8%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF+SS +VYG +P +E ++Y TK EM+ + I LR F
Sbjct: 122 LVFASSSSVYGAGSDMPFSEDSAADRPLSLYAATKR-ANEMMAHAYSHQYAMPITGLRLF 180
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
+ G P G P M FL + G+ L + G +G RD+ ++ D
Sbjct: 181 SVYG--PWGRPDMAP-------MMFLRAMLEGRS--LELHG------EGKAQRDFTYIDD 223
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ V L+ +V N+G G VS+ LV++ E ++ R ++
Sbjct: 224 VVEALVRVLDAAPTGLPLYRVLNVGRGTPVSMSRLVDLLEEHLGTTAWVEMRSSRSEEMD 283
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
A AD + + E G+ +T+E+ W
Sbjct: 284 ATCADVTALERETGFRPSVTLEQGLARLVAW 314
>UniRef50_A5UZF7 Cluster: NAD-dependent epimerase/dehydratase; n=5;
Chloroflexi (class)|Rep: NAD-dependent
epimerase/dehydratase - Roseiflexus sp. RS-1
Length = 321
Score = 49.2 bits (112), Expect = 9e-05
Identities = 52/204 (25%), Positives = 89/204 (43%), Gaps = 25/204 (12%)
Query: 13 PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLS-AADDKWNIISLRYFNPVGAHPSGLI 71
PE PI ETHPT + + YG +K + L L AA+ +++ R FN VG H
Sbjct: 130 PEETPIRETHPTRPL-SPYGVSK--VAAGLSGLQYAANYGLHVVVTRSFNHVGPHQGDRC 186
Query: 72 GEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNL 131
+ F M + ++PV+ V + RD+ H D+A AL L
Sbjct: 187 A---IQTFCRQMALIEHDR--QEPVIYVGNLEAR-------RDFTHTRDVAH----ALWL 230
Query: 132 LSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL--GDISAMWADTSLA 189
L + ++YNL +G + ++V + +R + ++ RL D + D +
Sbjct: 231 LLDHSVSGEIYNLCSGVATRIGDIVALVQRSGRVATEVRIDPSRLRPSDEPLLVGDNTKL 290
Query: 190 KEELGWSTQLTIEEMCTD---FWR 210
++ GW+ Q+ + M + +WR
Sbjct: 291 RQATGWAPQIDVPMMVEELMAYWR 314
>UniRef50_Q2ITF6 Cluster: DTDP-glucose 4,6-dehydratase; n=6;
Bacteria|Rep: DTDP-glucose 4,6-dehydratase -
Rhodopseudomonas palustris (strain HaA2)
Length = 345
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 10/107 (9%)
Query: 109 GTGIRDYIHVMDLASG--HVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAK 166
GT R +I D+A +AA L T Y++ T + V+++ELV + K
Sbjct: 226 GTSERSFIAASDVADATRRIAAAGTLGDT------YHIATDRIVTIRELVELICATMGVK 279
Query: 167 VP--LKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
++ V RLG SA D+ + ELGWS ++T+E+ D RW
Sbjct: 280 FEDHVEIVGERLGKDSAYRLDSGKIRRELGWSDRVTLEQGIDDTIRW 326
>UniRef50_A6CLM3 Cluster: UDP-glucose 4-epimerase; n=1; Bacillus sp.
SG-1|Rep: UDP-glucose 4-epimerase - Bacillus sp. SG-1
Length = 306
Score = 48.8 bits (111), Expect = 1e-04
Identities = 57/205 (27%), Positives = 91/205 (44%), Gaps = 25/205 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD-KWNIISLRY 59
+V+SS+ VYGE I+E I+ YG +KY E L+ K+ I LRY
Sbjct: 110 VVYSSTSAVYGENVASEISENEKIMPIS-FYGISKYTPELYLEAFFKIHGLKYTI--LRY 166
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N G G+ GE ++P F+ ++ + PV +FG DG RD+I+
Sbjct: 167 SNVYGER-QGIKGEG------GVIPIFIHELMEDRSPV--IFG------DGKQTRDFIYA 211
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+A +V+ALN ++V N+ +G +++ +L + V + R GD
Sbjct: 212 GDVAEANVSALNAAD-----MEVLNISSGISITILQLFEQIRDLMGKAVTPNFRGGRSGD 266
Query: 179 ISAMWADTSLAKEELGWSTQLTIEE 203
I S A L W ++ + E
Sbjct: 267 ILHSRLANSKAIMMLSWEPKVNLPE 291
>UniRef50_Q12VP0 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Methanococcoides burtonii DSM 6242|Rep: NAD-dependent
epimerase/dehydratase - Methanococcoides burtonii
(strain DSM 6242)
Length = 303
Score = 48.8 bits (111), Expect = 1e-04
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 33/205 (16%)
Query: 5 SSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVG 64
+S VYG P++ P+ E HPT N Y ++K I E L + D ++ISLR FN G
Sbjct: 109 ASTFVYGNPQYTPVDEKHPT-LPNNPYSQSK-LIGEELCNAYCRDYGIDVISLRLFNVYG 166
Query: 65 AHPSGLIGEDPTKEFTNLMP-FLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLAS 123
H G L+P + Q+ GK + D RD++++ D+
Sbjct: 167 PHQKG----------DYLIPHIIRQLESGK----------VSLKDPLPKRDFVYIDDVID 206
Query: 124 GHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNV------FERVTKAKVPLKYVDRRLG 177
AL+ V+N+ GK SV+E+ ++ FE+ +A + ++R
Sbjct: 207 SFECALD---SGLGGCNVFNIANGKSNSVREIADMLAETYFFEKGQRADIDYT-CEKRQS 262
Query: 178 DISAMWADTSLAKEELGWSTQLTIE 202
++S A+ AK + W + I+
Sbjct: 263 EVSDTIANIEKAKNIIKWEPKTDIK 287
>UniRef50_UPI0001597DB3 Cluster: SpsJ; n=1; Bacillus
amyloliquefaciens FZB42|Rep: SpsJ - Bacillus
amyloliquefaciens FZB42
Length = 315
Score = 48.4 bits (110), Expect = 2e-04
Identities = 57/219 (26%), Positives = 89/219 (40%), Gaps = 25/219 (11%)
Query: 1 MVFSSSCTVYGE--PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLR 58
++ S+ VYG+ P+ TET P S N Y +K ++L K I R
Sbjct: 120 LIHISTDEVYGDLAPDDPAFTETTPL-SPNNPYSASKAS-SDLLVMSYVRTHKLPAIITR 177
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N G P + ++P + + A+ PV ++G DG IRD++
Sbjct: 178 CSNNYG----------PYQHHEKMIPTIIRHAVNGTPV-PLYG------DGMQIRDWLFA 220
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D H A+ L+ + +YN+G G + KEL + + + +V+ R G
Sbjct: 221 ED----HCRAIKLVLEKGTLGDIYNIGGGNERTNKELASFIMKELGVEERFAHVEDRKGH 276
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPD 217
+ S K ELGW +T EE RW T + D
Sbjct: 277 DRRYAINASKLKNELGWRQDVTFEEGMRRTIRWYTDSQD 315
>UniRef50_Q97L35 Cluster: FUSION: Nucleoside-diphosphate-sugar
epimerase and GAF domain; n=1; Clostridium
acetobutylicum|Rep: FUSION: Nucleoside-diphosphate-sugar
epimerase and GAF domain - Clostridium acetobutylicum
Length = 725
Score = 48.4 bits (110), Expect = 2e-04
Identities = 62/214 (28%), Positives = 85/214 (39%), Gaps = 23/214 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+F+SS +VYG +L I E ++ Y KY + E ISLR N
Sbjct: 111 IFASSASVYGN-NNLTIKEEAEINPLSP-YAVNKY-VGEFYTQKWFEIYGLKTISLRISN 167
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G S + GE N++ AL K + FG DGT RD+I+V D+
Sbjct: 168 VFGPRQS-IKGEG------NVVALFINKAL-KSSEIDRFG------DGTQTRDFIYVEDV 213
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDISA 181
AL T V N+ T S+ EL++ E + + Y R GDI
Sbjct: 214 VDAIYKALES-DYTG----VLNISTNTEHSLNELIDTLEEFHPIR-KVNYRLNRSGDIKK 267
Query: 182 MWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMN 215
D S AK ELGW T+ + + W N
Sbjct: 268 SKLDNSKAKTELGWDTKYSFRAALEKTYDWYKKN 301
>UniRef50_O06485 Cluster: YfnG; n=3; Bacteria|Rep: YfnG - Bacillus
subtilis
Length = 301
Score = 48.4 bits (110), Expect = 2e-04
Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 20/214 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ +SS YG+ E+LP E P + G+ Y + + DL + + Y
Sbjct: 102 VIVASSDKAYGDQENLPYDENMP------LQGKHPYDVSKSCADLIS-----HTYFHTYG 150
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVAL-GKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
PV G + F ++P Q+ L G+ P + DGT +RDY ++
Sbjct: 151 LPVCITRCGNLYGGGDLNFNRIIPQTIQLVLNGEAPEIR--------SDGTFVRDYFYIE 202
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D ++ + + ++ + +N ++V ELV + + + K +++ +I
Sbjct: 203 DAVQAYLLLAEKMEENNLAGEAFNFSNEIQLTVLELVEKILKKMNSNLKPKVLNQGSNEI 262
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQT 213
+ A++ L W+ TI+E W T
Sbjct: 263 KHQYLSAEKARKLLNWTPAYTIDEGLEKTIEWYT 296
>UniRef50_Q93KX6 Cluster: Putative UDP-glucose 4-epimerase; n=1;
Streptomyces viridochromogenes|Rep: Putative UDP-glucose
4-epimerase - Streptomyces viridochromogenes
Length = 322
Score = 48.4 bits (110), Expect = 2e-04
Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 24/213 (11%)
Query: 1 MVFSSSC-TVYGEPEHLPITE-THPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLR 58
+VF+S+ +YGE +P E T P YG KY E+ + + + + LR
Sbjct: 121 VVFASTGGALYGEGVPVPTNEDTLPRPGAP--YGTAKYCAEKYIGLFNRLHGTEHSV-LR 177
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
N G S P E + + + G P TVFG DG+ RDY++V
Sbjct: 178 LGNVYGPRQS------PGGEAGVIAIYCGLASEGGVP--TVFG------DGSQTRDYVYV 223
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+A+ VA + TGKG +V E+++ + +P ++ RR G+
Sbjct: 224 GDVAAAFVAPYGTVGPAS-----GTSDTGKGSTVLEVLDHIAAASGRDLPPRFAPRRPGE 278
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
I D + +LGW+ + +E+ + W
Sbjct: 279 IQHSTLDVTRVAADLGWTASVPLEKGIAATYAW 311
>UniRef50_A1RUM8 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Pyrobaculum islandicum DSM 4184|Rep: NAD-dependent
epimerase/dehydratase - Pyrobaculum islandicum (strain
DSM 4184 / JCM 9189)
Length = 322
Score = 48.4 bits (110), Expect = 2e-04
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 26/209 (12%)
Query: 1 MVFSSSCTVYGEPEHLPITETH-----PTGSITNVYGRTKYFIEEMLKDLSAADDKWNII 55
+VF SS VYG+PE +P E++ P G + + Y +K F E + + ++
Sbjct: 121 VVFLSSSEVYGDPEVVPTPESYWGRVNPVG-VRSPYDESKRFGEALCMAF-RREYGVDVR 178
Query: 56 SLRYFNPVGAHPSGLIGEDPTKEFTNLM-PFLAQVALGKKPVLTVFGTDYNTPDGTGIRD 114
R FN G DP + ++ FL Q AL +P+ TV G DG R
Sbjct: 179 VARIFNTYGPR------LDPDSSYARVVTKFLVQ-ALRGEPI-TVHG------DGLQTRS 224
Query: 115 YIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDR 174
+ +V D+ +G + + +VYN+G+ + V++ EL + + V + P+ +
Sbjct: 225 FAYVSDVVNG---LITIAHCERCAGEVYNVGSDEEVTILELAKLVKEVAGSASPIVHTPP 281
Query: 175 RLGDISAMWADTSLAKEELGWSTQLTIEE 203
R D D S + LGW + ++E
Sbjct: 282 RPDDPRRRRPDLSKLR-ALGWEPVVKLKE 309
>UniRef50_Q11EM0 Cluster: NAD-dependent epimerase/dehydratase; n=16;
Proteobacteria|Rep: NAD-dependent epimerase/dehydratase
- Mesorhizobium sp. (strain BNC1)
Length = 367
Score = 48.0 bits (109), Expect = 2e-04
Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTG--KGVSVKELVNVFERVTKA 165
+G +RD +HV D + + L+ + R +NLG G VS++ ++ R+T
Sbjct: 246 NGKQVRDVLHVSDAVAAYRRVLDNIDAVSGR--TFNLGGGVRNAVSLRLVLQEIRRITGT 303
Query: 166 KVPLKYVDRRLGDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ + + D R GD ADT+ + ELGWS + E D W
Sbjct: 304 EPVVGWGDWRAGDQYYFVADTTRLQSELGWSATIGWREGLKDLADW 349
>UniRef50_A5UZ84 Cluster: NAD-dependent epimerase/dehydratase; n=5;
Chloroflexi (class)|Rep: NAD-dependent
epimerase/dehydratase - Roseiflexus sp. RS-1
Length = 317
Score = 48.0 bits (109), Expect = 2e-04
Identities = 54/212 (25%), Positives = 90/212 (42%), Gaps = 24/212 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +S+ +VYG P +E PT + Y TK E+L + I +R+F
Sbjct: 122 LVLASTSSVYGLSP-TPWSEESPTDRPLSFYAATKK-AAEVLAYTAHRRHGIPIRIVRFF 179
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGI-RDYIHVM 119
G P G D T F+ + GK +T+F G G+ RD+ ++
Sbjct: 180 TVYG--PRGR--PDMTPHL-----FVDAMVAGK--AITLFN------GGIGVYRDWTYIA 222
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDI 179
D+ +G +AAL++ +++NLG V + + V E VT + + D
Sbjct: 223 DIVAGVIAALDM----DAAFEIFNLGHSSPVQLIDFVRTLEEVTGLRAGIVAQPLPAADP 278
Query: 180 SAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+A A + LG+ + ++EE FW W
Sbjct: 279 PVTFARIDKATQMLGFQPRTSLEEGLARFWEW 310
>UniRef50_Q5SKQ2 Cluster: UDP-glucose 4-epimerase; n=4; Thermus|Rep:
UDP-glucose 4-epimerase - Thermus thermophilus (strain
HB8 / ATCC 27634 / DSM 579)
Length = 311
Score = 47.6 bits (108), Expect = 3e-04
Identities = 56/170 (32%), Positives = 80/170 (47%), Gaps = 24/170 (14%)
Query: 1 MVFSSSC-TVYGE-PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADD-KWNIISL 57
+VF+S+ +YGE PE ET P + Y +K E L + KW +SL
Sbjct: 112 LVFASTGGAIYGEVPEGERAEETWPPRP-KSPYAASKAAFEHYLSVYGQSYGLKW--VSL 168
Query: 58 RYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTG-IRDYI 116
RY N G +DP E ++ A+ L PV T++ TP G +RDY+
Sbjct: 169 RYGNVYGPR------QDPHGE-AGVVAIFAERVLKGLPV-TLYAR--KTPGDEGCVRDYV 218
Query: 117 HVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKE-LVNVFERVTKA 165
+V D+A H AL L +YN+GTG+G + +E L+ V E KA
Sbjct: 219 YVGDVAEAHALALFSLE------GIYNVGTGEGHTTREVLMAVAEAAGKA 262
>UniRef50_Q1VGF9 Cluster: Putative uncharacterized protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Putative
uncharacterized protein - Psychroflexus torquis ATCC
700755
Length = 268
Score = 47.6 bits (108), Expect = 3e-04
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 17/161 (10%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
V +SS VYG + P+ E+ G+ + Y +K+ E+ + L A + ++LR+FN
Sbjct: 65 VLASSAAVYGTNDAFPLDESD-AGAFHSPYADSKWQNEQQV--LKAKEAGMEAVALRFFN 121
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDL 121
G G+ + ++P ++A+G + T+FG DG RD++HV D+
Sbjct: 122 VYGT------GQRADGAYAAVIPKFIELAVGGRAP-TIFG------DGLQTRDFVHVDDV 168
Query: 122 ASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERV 162
A + L T VYN+ T +S+ +L++ +
Sbjct: 169 AQA-LLLLATEPWTDEFEHVYNVCTQTEISLLDLLSTIHNI 208
>UniRef50_A7TUR9 Cluster: Putative nucleoside-diphosphate-sugar
epimerases; n=1; Streptomyces lividans|Rep: Putative
nucleoside-diphosphate-sugar epimerases - Streptomyces
lividans
Length = 332
Score = 47.6 bits (108), Expect = 3e-04
Identities = 50/201 (24%), Positives = 89/201 (44%), Gaps = 22/201 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V +SS +VYG + ET + Y TK E++ + +++LRYF
Sbjct: 132 LVVASSSSVYGPTDGDASRETDRPNP-ASPYAVTKLAEEQLCLAYAERPVGPGVVALRYF 190
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G + FT+ + AL +P L ++G DG RD+ ++ D
Sbjct: 191 TVYGPRQRADM-------FTHRALY---AALAGQP-LRLYG------DGHQRRDFTYIDD 233
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ + +AA ++ H + N+G G S+ +++N+ +T ++ L R GD+
Sbjct: 234 VVAATIAA-GVVPNAHGTI---NVGGGSNASLLDVINIANSLTGREIQLHQDHVRNGDVL 289
Query: 181 AMWADTSLAKEELGWSTQLTI 201
AD AKE LGW ++ +
Sbjct: 290 LTRADPGRAKEVLGWQPRVDL 310
>UniRef50_Q97A85 Cluster: NDP-sugar epimerase; n=3;
Thermoplasmatales|Rep: NDP-sugar epimerase -
Thermoplasma volcanium
Length = 256
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/83 (30%), Positives = 50/83 (60%), Gaps = 4/83 (4%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
DG+ IRD+++V D+ + +L++ + R Y +G+GKG SV +L+++ E+VT K+
Sbjct: 157 DGSHIRDFLYVGDVP---ITIERILNEKY-RTGEYEVGSGKGTSVNDLISLIEKVTGKKI 212
Query: 168 PLKYVDRRLGDISAMWADTSLAK 190
++ D + + S + A ++ K
Sbjct: 213 RTRHEDYIVPEASELVAKNTIVK 235
>UniRef50_Q9SYM5 Cluster: Probable rhamnose biosynthetic enzyme 1;
n=30; root|Rep: Probable rhamnose biosynthetic enzyme 1
- Arabidopsis thaliana (Mouse-ear cress)
Length = 669
Score = 47.6 bits (108), Expect = 3e-04
Identities = 61/219 (27%), Positives = 92/219 (42%), Gaps = 31/219 (14%)
Query: 5 SSCTVYGEPEHLPITETHPTGSI--TNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
S+ VYGE + + H + TN Y TK E ML +I+ R N
Sbjct: 131 STDEVYGETDEDALVGNHEASQLLPTNPYSATKAGAE-MLVMAYGRSYGLPVITTRGNNV 189
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G + + P K L+P +A+ + VL + G DG+ +R Y++ D+A
Sbjct: 190 YGPN------QFPEK----LIPKFILLAM-RGQVLPIHG------DGSNVRSYLYCEDVA 232
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSV----KELVNVFERVTKAKVPLKYVDRRLGD 178
L+ H VYN+GT K V K++ +F +A + K+VD R +
Sbjct: 233 EAFEVVLHKGEVGH----VYNIGTKKERRVNDVAKDICKLFNMDPEANI--KFVDNRPFN 286
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQTMNPD 217
+ D K+ LGWS + T EE W T NP+
Sbjct: 287 DQRYFLDDQKLKK-LGWSERTTWEEGLKKTMDWYTQNPE 324
>UniRef50_Q9RWF7 Cluster: UDP-glucose 4-epimerase, putative; n=63;
cellular organisms|Rep: UDP-glucose 4-epimerase,
putative - Deinococcus radiodurans
Length = 344
Score = 47.2 bits (107), Expect = 4e-04
Identities = 53/217 (24%), Positives = 91/217 (41%), Gaps = 25/217 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++ +S+ VYG +PI E+HP + Y TK +++ + + +++LR F
Sbjct: 134 VIHTSTSEVYGTARSVPIHESHPLQG-QSPYSATKIGADKLAESYFLSFGL-PVVTLRPF 191
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G S PT ++Q+A G+ T+ D RD+ +V D
Sbjct: 192 NTYGPRQSAR-AVIPT--------IISQLAAGR--------TEIKLGDLRPTRDFNYVAD 234
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL---- 176
A A + + + N G+G+ +SV + V + +V V +K D RL
Sbjct: 235 TARAFRAVGE--AGPEVLGRTLNAGSGREISVGDTVKLIAQVMGKDVEVKQEDERLRPEG 292
Query: 177 GDISAMWADTSLAKEELGWSTQLTIEEMCTDFWRWQT 213
++ + AD + GW Q+T+EE W T
Sbjct: 293 SEVMRLLADHRELQTLTGWQPQVTLEEGLKRTAEWFT 329
>UniRef50_Q84CM4 Cluster: Nucleotide sugar epimerase; n=4;
Proteobacteria|Rep: Nucleotide sugar epimerase -
Zymomonas mobilis
Length = 337
Score = 47.2 bits (107), Expect = 4e-04
Identities = 53/204 (25%), Positives = 88/204 (43%), Gaps = 27/204 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
MV++SS +VYG LP ++Y TK EML + A + + LR+F
Sbjct: 124 MVYASSSSVYGNRSTLPFKVDSQPDYPASLYAATKR-AGEMLSESYAYLYRIPLTGLRFF 182
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G I P M + L K+P++ +N +G RD+ ++ D
Sbjct: 183 TVYG------IWGPPDM----AMWIFTKKILQKQPIML-----FN--NGEMQRDFTYIDD 225
Query: 121 LASGHVAALNLLSQTHIRLK---------VYNLGTGKGVSVKELVNVFERVTKAKVPLKY 171
SG +AAL+ Q + ++K +YN+G ++K LV + E +
Sbjct: 226 AVSGLIAALDNPPQDNNKIKSGGSLNPHNLYNIGNHHPENLKYLVELLEEACGCHAIKEL 285
Query: 172 VDRRLGDISAMWADTSLAKEELGW 195
+ GD+S +AD +K +LG+
Sbjct: 286 RPMQAGDVSTTYADIETSKRDLGF 309
>UniRef50_A4EVQ8 Cluster: NAD-dependent epimerase/dehydratase family
protein; n=1; Roseobacter sp. SK209-2-6|Rep:
NAD-dependent epimerase/dehydratase family protein -
Roseobacter sp. SK209-2-6
Length = 342
Score = 47.2 bits (107), Expect = 4e-04
Identities = 50/202 (24%), Positives = 84/202 (41%), Gaps = 21/202 (10%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F SS VYG+ LP+TE P + N Y R+K E+ ++ +D + LR+
Sbjct: 121 LIFGSSREVYGQSNLLPVTENTPLRPM-NDYARSKVAAEKAVQ--RVGEDGFRTAVLRFS 177
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G+ + ++P + AL P L V G I D HV D
Sbjct: 178 TVYGS---------ASDHRDRVIPAFCRAALSNHP-LRVEG-------AANILDITHVSD 220
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+A + + LS L +L TG+G S+ +L + R++++ + R D+
Sbjct: 221 VADNIMNVVRSLSAGK-SLDPMHLTTGQGTSLMDLAHSVVRLSQSDSEIVTATSRDFDVK 279
Query: 181 AMWADTSLAKEELGWSTQLTIE 202
D LA+ W ++E
Sbjct: 280 QFVGDPKLAETLTDWCPGFSLE 301
>UniRef50_A7D6Z2 Cluster: NAD-dependent epimerase/dehydratase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: NAD-dependent
epimerase/dehydratase - Halorubrum lacusprofundi ATCC
49239
Length = 345
Score = 47.2 bits (107), Expect = 4e-04
Identities = 53/214 (24%), Positives = 91/214 (42%), Gaps = 25/214 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+ F S V G+P+ PIT P + N YGRTK E ++ + AD +
Sbjct: 134 LAFPFSMAVLGDPQSFPITADQPRDPL-NWYGRTKLLGERAIE--TFADGAFPAHLFLKS 190
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G H + + T ++ F AL + LTV+ GT R+++HV D
Sbjct: 191 NLYGEH----VVDGTTVSKPTVINFFVNRALAGE-TLTVY------EPGTQARNFVHVKD 239
Query: 121 LASGHVAA----LNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVT----KAKVPLKYV 172
+A +V + L L+ + + + + + +SV E+ + V + V ++ V
Sbjct: 240 VARVYVRSAERLLEQLASGETGTETFEIASEEDMSVMEVAEIVREVAHEEREIDVDVELV 299
Query: 173 DR-RLGD--ISAMWADTSLAKEELGWSTQLTIEE 203
+ R + + D S A E LGW+ ++ E
Sbjct: 300 ENPRSAETMVEEFGVDISAAGERLGWAPSESVNE 333
>UniRef50_P95780 Cluster: dTDP-glucose 4,6-dehydratase; n=123;
Bacteria|Rep: dTDP-glucose 4,6-dehydratase -
Streptococcus mutans
Length = 348
Score = 47.2 bits (107), Expect = 4e-04
Identities = 34/122 (27%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVN-VFERVTKAK 166
+G +RD+IH D ++G A +L++ I + Y +G + KE++ + E++++ K
Sbjct: 220 EGKNVRDWIHTNDHSTGVWA---ILTKGRIG-ETYLIGADGEKNNKEVLELILEKMSQPK 275
Query: 167 VPLKYVDRRLGDISAMWADTSLAKEELGWSTQLT-IEEMCTDFWRWQTMNPDGYPKKTKK 225
+V R G D++ +EELGW Q T EE D +W T + D + + +
Sbjct: 276 NAYDHVTDRAGHDLRYAIDSTKLREELGWKPQFTNFEEGLEDTIKWYTEHEDWWKAEKEA 335
Query: 226 TE 227
E
Sbjct: 336 VE 337
>UniRef50_Q5FRS4 Cluster: UDP-N-acetylglucosamine 4-epimerase; n=1;
Gluconobacter oxydans|Rep: UDP-N-acetylglucosamine
4-epimerase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 322
Score = 46.8 bits (106), Expect = 5e-04
Identities = 50/211 (23%), Positives = 88/211 (41%), Gaps = 19/211 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+V++SS +VYG + +P ET ++VY TK E++ + A LR+F
Sbjct: 124 VVYASSSSVYGRNQSVPFRETDRVERPSSVYAVTKR-AAELMSESYAYLHGIPQTGLRFF 182
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
G P G P + F ++ G+ PV G + RD+ ++ D
Sbjct: 183 TVYG--PWGR----PDMAYYG---FAKAISEGR-PVTLYEGKHLS-------RDFTYIDD 225
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGDIS 180
+ G L + + +V NLG K V ++ + E+ K ++ R + D+
Sbjct: 226 IVRGVQQVLGRPPEAGMS-RVLNLGGDKPERVTRMIELLEQNLGKKAFVERRPRPVADME 284
Query: 181 AMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
+ WA +E GW ++ E+ +F W
Sbjct: 285 STWASLENVREFCGWKPAVSFEDGMKEFCLW 315
>UniRef50_Q2SJW4 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=1; Hahella chejuensis KCTC 2396|Rep:
Nucleoside-diphosphate-sugar epimerase - Hahella
chejuensis (strain KCTC 2396)
Length = 318
Score = 46.8 bits (106), Expect = 5e-04
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 21/157 (13%)
Query: 4 SSSCTVYGEP-EHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNP 62
SS TVYG PI E+ T I+ +YG +K IE + L I R N
Sbjct: 119 SSGGTVYGNQLSRQPIAESSSTKPIS-LYGTSKLIIEN-IGFLYNVQKNLPFIVARPGNA 176
Query: 63 VGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLA 122
G G+ P + + A G+ VL +FG DG+ +RDYIH DLA
Sbjct: 177 YGP------GQKPFRGQGFVATAFASALKGE--VLNIFG------DGSVVRDYIHARDLA 222
Query: 123 SGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVF 159
VA L + YN+GT GV++ L+N +
Sbjct: 223 DALVAILRFGKLG----EAYNIGTSNGVALHTLLNEY 255
>UniRef50_Q1VUM7 Cluster: UDP-glucose 4-epimerase; n=1;
Psychroflexus torquis ATCC 700755|Rep: UDP-glucose
4-epimerase - Psychroflexus torquis ATCC 700755
Length = 306
Score = 46.8 bits (106), Expect = 5e-04
Identities = 49/201 (24%), Positives = 87/201 (43%), Gaps = 25/201 (12%)
Query: 2 VFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFN 61
+++SS +VYG+ E+LP+TE T ++Y K E L S +D K ++SLR FN
Sbjct: 111 IYASSMSVYGDHENLPVTEESVT-MPKSLYAVGKLASEHYLNIYSNSDLK--VVSLRLFN 167
Query: 62 PVGAHPSGLIGEDPTKEFTNLMPFLAQVALG---KKPVLTVFGTDYNTPDGTGIRDYIHV 118
G P + NL + + L K + V G+ RD +++
Sbjct: 168 VYG----------PGQNLANLKQGMLSIYLAQALKDGQIKVKGSLER------FRDLVYI 211
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRLGD 178
D+ V +L + + VYN+ V VKE++ + V + +K ++ GD
Sbjct: 212 DDVV--EVVSLLVTTDLSNPYSVYNVANAYPVKVKEMITSIKAVL-GNISVKEIEGTQGD 268
Query: 179 ISAMWADTSLAKEELGWSTQL 199
++ ++ GW ++
Sbjct: 269 QFGIFGSNYSLMKDFGWKPKI 289
>UniRef50_Q97H47 Cluster: Nucleoside-diphosphate-sugar epimerase;
n=6; Clostridium|Rep: Nucleoside-diphosphate-sugar
epimerase - Clostridium acetobutylicum
Length = 332
Score = 46.4 bits (105), Expect = 6e-04
Identities = 52/213 (24%), Positives = 89/213 (41%), Gaps = 24/213 (11%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
+VF S+C VY I E H ++ YG +K E M+ A K + +R F
Sbjct: 136 VVFMSTCMVYDISGETGIDEQHSVKPVSP-YGGSKIAAENMVLSYFNAY-KLPAVVIRPF 193
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G GE ++ + + KP+ ++G+ T RD + V D
Sbjct: 194 NTYGPFQKSN-GEG------GVVSIFLKNFIDNKPI-NIYGSGKQT------RDLLFVKD 239
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVD--RRLGD 178
A +N ++ + ++ N GTG +++ EL N+ + KV + +V+ +
Sbjct: 240 CAD---FVVNAGYKSEVDGEIINAGTGNDITINELANL---IAGKKVSVNHVEHIHPQSE 293
Query: 179 ISAMWADTSLAKEELGWSTQLTIEEMCTDFWRW 211
I + + S AK +GW T+EE + W
Sbjct: 294 IMKLKCNYSKAKNLMGWEPHYTLEEGIAETKSW 326
>UniRef50_Q0EXU3 Cluster: ADP-L-glycero-D-manno-heptose-6-epimerase;
n=1; Mariprofundus ferrooxydans PV-1|Rep:
ADP-L-glycero-D-manno-heptose-6-epimerase -
Mariprofundus ferrooxydans PV-1
Length = 319
Score = 46.4 bits (105), Expect = 6e-04
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 19/204 (9%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSIT-NVYGRTKYFIEEMLKDLSAADDKWNIISLRY 59
+V++SS YG P +G N+YG +K ++ + +I LRY
Sbjct: 112 VVYASSAGTYGNS---PAPNKVGSGEEPENIYGFSKLAMDRIAYRWYDRHPA-PLIGLRY 167
Query: 60 FNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVM 119
FN G + D K + ++ Q+ G+ P L +G +RD++++
Sbjct: 168 FNVFGPGETHKNERDGNKTASMILQLYEQMKSGRNPRLFKYGEQ--------MRDFVYIR 219
Query: 120 DLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDR-RLGD 178
D+ + ++AALN R V N+G+G+ + ++V++ ++Y+D
Sbjct: 220 DVINANLAALNA-----PRSGVCNVGSGQARTFNDIVHITAETLGIDAKIEYMDNPHTFY 274
Query: 179 ISAMWADTSLAKEELGWSTQLTIE 202
+ AD S + LGW + ++E
Sbjct: 275 QNHTEADVSDSHALLGWQPEWSLE 298
>UniRef50_A3S1P1 Cluster: Putative LPS biosynthesis related
DNTP-hexose dehydratase-epimerase; n=1; Prochlorococcus
marinus str. MIT 9211|Rep: Putative LPS biosynthesis
related DNTP-hexose dehydratase-epimerase -
Prochlorococcus marinus str. MIT 9211
Length = 307
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 12/134 (8%)
Query: 83 MPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVY 142
+PF+ + + KK ++ +G +RDY +V D S A N + ++
Sbjct: 184 LPFIIKECINKK--------EFKVTEGYQLRDYCYVKDFTS---AIRNCIENKSAYGEII 232
Query: 143 NLGTGKGVSVKELVNVFERVTKAKVPL-KYVDRRLGDISAMWADTSLAKEELGWSTQLTI 201
N+G+GK +S++E+ N + PL V R + A++ + AK L WS +
Sbjct: 233 NIGSGKPISIREVTNKVVNIIGYGKPLYGEVAYRDSESMALYPNLEKAKSILNWSANYEM 292
Query: 202 EEMCTDFWRWQTMN 215
E+ W N
Sbjct: 293 EDSLYSVINWYKNN 306
>UniRef50_Q980W1 Cluster: UDP-glucose 4-epimerase; n=4;
Sulfolobaceae|Rep: UDP-glucose 4-epimerase - Sulfolobus
solfataricus
Length = 311
Score = 46.4 bits (105), Expect = 6e-04
Identities = 54/210 (25%), Positives = 89/210 (42%), Gaps = 28/210 (13%)
Query: 1 MVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYF 60
++F+SS TVYGE +P E+ I+N YG K E ++K A IS R
Sbjct: 108 VIFTSSSTVYGETSKIPTPESEELKPISN-YGLFKLLCENIVK-YYAEQYGIKSISTRLA 165
Query: 61 NPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMD 120
N G S + D K+ + P L ++ LG +G + Y+++ D
Sbjct: 166 NITGGRVSHGVVIDFIKKLKD-NPNLLEI-LG---------------NGKQRKSYLYIDD 208
Query: 121 LASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKY----VDRR- 175
L V +++ + V+N+G ++V E+ + K + Y D R
Sbjct: 209 LIEAFVMLEKKVNRIY---DVFNIGNNDSITVDEIAKIVIDEMKLSPRITYKNPTADGRG 265
Query: 176 -LGDISAMWADTSLAKEELGWSTQLTIEEM 204
GD+ M D S E+GWS +++ E+
Sbjct: 266 WPGDVRLMLLDISKISREVGWSPKMSSREV 295
>UniRef50_Q474T2 Cluster: NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid
dehydrogenase/isomerase:dTDP-4-dehydrorhamnose
reductase; n=1; Ralstonia eutropha JMP134|Rep:
NAD-dependent epimerase/dehydratase:3-beta
hydroxysteroid
dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 322
Score = 46.0 bits (104), Expect = 8e-04
Identities = 57/218 (26%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 1 MVFSSSCTVYGE--PEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLR 58
+V + S YGE + +PI E+HP + + YG +K EML ++ + R
Sbjct: 114 VVVACSSAQYGEVQADAIPIKESHPLRPM-HPYGVSKV-ATEMLAMQYWVNNGIRSVCAR 171
Query: 59 YFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHV 118
FN G +G D +FT + + Q + PVL V + + R V
Sbjct: 172 IFNTTGPRKTG----DVCADFTYRVARIEQGLI--PPVLRVGNLETH-------RAITDV 218
Query: 119 MDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYVDRRL-- 176
DLA AL LL++ VYN+ + ++E+V++ + + L+ D+ L
Sbjct: 219 RDLAR----ALELLAERGAPGGVYNVSGSRAYQIREIVDLIQAASTISFTLE-TDQALLR 273
Query: 177 -GDISAMWADTSLAKEELGWSTQLTIEEMCTD---FWR 210
D ++ D+S E GW+ ++TI + D +WR
Sbjct: 274 PSDEKVIFGDSSSLVEATGWAQEVTIAKTIGDMLAYWR 311
>UniRef50_Q0S8T5 Cluster: UDP-glucose 4-epimerase; n=25;
Actinobacteria (class)|Rep: UDP-glucose 4-epimerase -
Rhodococcus sp. (strain RHA1)
Length = 355
Score = 46.0 bits (104), Expect = 8e-04
Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 108 DGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKV 167
DG RD++HV D+A+ +VAA+ +N+ +G +++ E+ R
Sbjct: 242 DGRQTRDFVHVHDVAAANVAAVEAALPG---FAAFNVCSGHPITIGEVAATLARSHGGPE 298
Query: 168 PLKYVDRRLGDISAMWADTSLAKEELGWSTQL 199
P+ + R GD+ + AD LA+E LG+ Q+
Sbjct: 299 PVVTGEYRPGDVRHIVADPWLARERLGFRAQI 330
>UniRef50_A7UH60 Cluster: Putative epimerase/dehydratase; n=1;
Desulfotignum phosphitoxidans|Rep: Putative
epimerase/dehydratase - Desulfotignum phosphitoxidans
Length = 322
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 14/152 (9%)
Query: 55 ISLRYFNPVGAHPSGLIGEDPTK--EFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGI 112
I L N GA ++ + + E M AL +P+ VFG DG
Sbjct: 163 IGLNIQNCYGARERAILNPNTYRPGEGRKFMASAIIAALKNEPI-PVFG------DGEQS 215
Query: 113 RDYIHVMDLASGHVAALNLLSQTHIRLKVYNLGTGKGVSVKELVNVFERVTKAKVPLKYV 172
D++H+ D+ V AL L +V + G G+ +++ ++ + +TK+K ++++
Sbjct: 216 SDWVHIDDI----VEALVLAPCDAAVGQVMDFGVGESITINKIAQIVIEMTKSKSKIEHL 271
Query: 173 DRRLGDISA-MWADTSLAKEELGWSTQLTIEE 203
R G+ AD + AKE LGW ++ + E
Sbjct: 272 PMRTGEAKVHTKADNAPAKEYLGWEPKIDLRE 303
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.134 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 282,148,019
Number of Sequences: 1657284
Number of extensions: 11851220
Number of successful extensions: 26200
Number of sequences better than 10.0: 434
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 25526
Number of HSP's gapped (non-prelim): 493
length of query: 234
length of database: 575,637,011
effective HSP length: 98
effective length of query: 136
effective length of database: 413,223,179
effective search space: 56198352344
effective search space used: 56198352344
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 71 (32.7 bits)
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